Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1Node2LinkStrengthCommIsNode1Hub?IsNode2Hub?Node1ConsNode2ConsNode1ShellNode2Shell
E1Lig16.87251NoYes4010
E2Lig35.28251YesYes3010
7x31Lig23.6250NoYes3010
E2x51Lig8.63751NoYes4010
E2x52Lig5.80251NoYes4010
6x62Lig5.99251NoYes3010
4x65Lig5.19251YesYes4010
6x51Lig14.31YesYes6010
7x34Lig6.7751NoYes5010
7x38Lig30.3651NoYes5010
2x60Lig18.581YesYes6010
7x39Lig7.94251YesYes5010
7x42Lig15.61251YesYes7010
3x32Lig4.2051NoYes6010
3x36Lig9.441NoYes7010
6x55Lig5.82251NoYes5010
6x58Lig9.97251NoYes4010
1x311x356.811NoNo3522
1x317x353.991NoNo3421
1x322x678.630NoNo5322
1x32E15.2850NoNo5421
1x357x355.7851NoNo5421
1x357x395.63251NoYes5521
1x397x3915.47250NoYes6521
2x577x4212.3350NoYes8721
2x602x636.07751YesNo6512
2x603x298.75751YesNo6512
2x647x394.39750NoYes5521
2x67E25.81751NoYes3321
E1x49E212.65250NoYes5321
3x22E26.1251NoYes3321
3x294x6522.8951NoYes5421
3x29E2x504.32751NoYes5922
3x366x483.991NoYes7912
4x64E212.6651NoYes4321
4x645x356.42251NoNo4222
4x65E2x505.22251YesYes4912
4x65E2x5210.1851YesNo4411
E2E241.1551YesYes3311
E2E2x519.3351YesNo3411
E2E2x529.93251YesNo3411
5x35E29.6751NoYes2321
5x36E26.77751NoYes4321
5x39E24.66250NoYes5321
5x366x6214.54251NoNo4321
6x516x525.06251YesNo6812
6x516x554.91751YesNo6511
6x517x387.8751YesNo6511
6x547x344.020NoNo5521
6x586x626.551NoNo4311
6x617x277.62751NoNo3311
7x397x425.4551YesYes5711
2x537x428.6250NoYes7721
2x607x393.5051YesYes6511
2x64E15.02250NoNo5421
3x363x374.19251NoYes7712
6x61Lig8.861NoYes3010
7x27Lig3.71251NoYes3010
7x35Lig6.691NoYes4010
1x28Lig16.9951NoYes0010
1x287x323.4151NoNo0212
2x563x323.08750NoNo6621
LigNT2.73251YesNo0001
7x247x272.660NoNo8321
6x617x302.551NoNo3512
1x251x281.350NoNo0021
3x21E21.310NoYes8321

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Consensus Members
Id Members
bk2_on 7F2O-BK2-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7F6I-BK2-Kallidin-Gq/&β;1/&γ;2
bk1_on 7EIB-BK1-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
Net Summary
Imin 3.44
Number of Linked Nodes 285
Number of Links 317
Number of Hubs 35
Number of Links mediated by Hubs 159
Number of Communities 5
Number of Nodes involved in Communities 51
Number of Links involved in Communities 74
Path Summary
Number Of Nodes in MetaPath 64
Number Of Links MetaPath 63
Number of Shortest Paths 46765
Length Of Smallest Path 3
Average Path Length 12.4184
Length of Longest Path 28
Minimum Path Strength 0.5525
Average Path Strength 7.00763
Maximum Path Strength 26.1042
Minimum Path Correlation 0.7
Average Path Correlation 0.925312
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 4.16667
Average % Of Corr. Nodes 50.2259
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 40.1115
Maximum Path Hubs % 100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
IdComponents
peptide_onopioid_on
angiotensin_on
bombesin_on
cck_on
endothelin_on
ghrelin_on
npy_on
nts_on
orexin_on
vasopressin-ot_on
tachykinin_on
sst_on
relaxin_on
trh_on
nmur_on
motilin_on
melanocortin_on
galanin_on
fpr-alx_on
compl-peptide_on
bradykinin_on
apelin_on



You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download bradykinin_on.zip



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