psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.33	5.733	No	No	0	7	4
2	G.HN.36	b.b5x2	3.482	No	Yes	0	4	7
3	G.HN.37	b.b5x2	3.99967	No	Yes	0	3	7
4	G.HN.40	b.b5x2	8.35133	No	Yes	0	7	7
5	G.HN.40	b.b5x3	4.85544	No	Yes	0	7	9
6	G.HN.43	b.b5x3	7.12478	No	Yes	0	9	9
7	G.HN.44	b.b5x3	9.706	No	Yes	0	6	9
8	G.HN.47	b.b4x2	3.68167	No	No	0	6	8
9	G.HN.50	b.b4x2	6.745	No	No	0	5	8
10	G.HN.51	b.l1x4	3.91133	No	No	0	5	6
11	4x36	G.HN.52	3.816	No	No	0	8	4
12	G.S1.01	G.S3.02	4.08778	No	No	0	6	4
13	G.S1.01	G.S3.04	10.2809	No	Yes	0	6	6
14	G.S1.02	G.S3.01	3.45667	Yes	Yes	6	5	4
15	G.S1.02	G.S3.03	5.61067	Yes	Yes	6	5	7
16	G.S1.02	G.h2s4.05	9.02044	Yes	No	0	5	7
17	G.H5.15	G.S1.02	3.06244	Yes	Yes	6	7	5
18	G.S1.03	G.S3.06	3.93556	No	Yes	0	9	5
19	G.S1.04	G.S3.03	4.65544	No	Yes	0	7	7
20	G.S1.04	G.S3.05	3.15644	No	Yes	0	7	7
21	G.S1.04	G.S4.03	4.70989	No	Yes	0	7	7
22	G.S1.05	G.S1.07	6.13489	No	No	0	9	9
23	G.S1.05	G.h2s4.01	16.0633	No	Yes	0	9	9
24	G.S1.05	G.S4.02	5.35944	No	Yes	0	9	8
25	G.H1.01	G.S1.06	5.93767	Yes	Yes	5	9	8
26	G.S1.06	G.S3.05	7.60267	Yes	Yes	0	8	7
27	G.S1.06	G.S3.07	4.11778	Yes	No	5	8	9
28	G.S1.06	G.S4.03	3.13622	Yes	Yes	5	8	7
29	G.H3.12	G.S1.07	4.08978	No	No	0	8	9
30	G.H1.01	G.s1h1.01	3.17589	Yes	No	0	9	9
31	G.H3.01	G.s1h1.04	8.18756	Yes	No	0	9	9
32	G.S5.07	G.s1h1.06	3.37644	Yes	No	0	9	9
33	G.H1.01	G.S3.07	8.97067	Yes	No	5	9	9
34	G.H1.01	G.S4.05	3.33711	Yes	Yes	5	9	7
35	G.H1.04	G.S4.05	3.26322	No	Yes	5	7	7
36	G.H1.04	G.S5.05	4.43744	No	Yes	5	7	9
37	G.H1.04	G.S5.07	4.84356	No	Yes	5	7	9
38	G.H1.07	G.s6h5.05	2.97367	No	No	5	9	9
39	G.H1.07	G.H5.03	3.00667	No	Yes	5	9	8
40	G.H1.08	G.S2.06	5.97056	No	No	0	8	9
41	G.H1.08	G.S3.05	3.38589	No	Yes	0	8	7
42	G.hfs2.06	b.l7x4	2.99022	No	Yes	0	7	9
43	G.hfs2.07	b.l7x4	4.45056	No	Yes	0	9	9
44	G.S2.01	b.l5x5	4.16256	No	Yes	1	9	9
45	G.S2.01	b.l7x2	3.61422	No	Yes	1	9	9
46	G.S2.03	G.S2.05	6.468	Yes	No	1	9	3
47	G.S2.03	G.S3.04	7.307	Yes	Yes	1	9	6
48	G.S2.03	G.S3.06	8.60233	Yes	Yes	1	9	5
49	G.S2.05	G.S3.04	9.54844	No	Yes	1	3	6
50	G.S2.06	G.S3.03	15.9204	No	Yes	0	9	7
51	G.S2.07	G.S3.02	7.45133	No	No	0	3	4
52	G.S2.08	G.s2s3.01	7.79333	Yes	No	6	5	4
53	G.H5.04	G.S2.08	5.54922	No	Yes	0	7	5
54	G.H5.05	G.S2.08	5.63878	No	Yes	6	5	5
55	G.H5.08	G.S2.08	8.596	Yes	Yes	6	8	5
56	G.H5.05	G.s2s3.01	7.51611	No	No	6	5	4
57	G.H5.08	G.s2s3.01	6.98222	Yes	No	6	8	4
58	G.S3.01	G.S3.03	6.13622	Yes	Yes	6	4	7
59	G.H5.08	G.S3.01	4.09578	Yes	Yes	6	8	4
60	G.S3.01	I2x51	6.38956	Yes	Yes	6	4	6
61	G.H5.08	G.S3.03	3.24122	Yes	Yes	6	8	7
62	G.H5.11	G.S3.03	4.41356	No	Yes	0	8	7
63	G.S3.04	G.S3.06	4.64989	Yes	Yes	1	6	5
64	G.S3.06	b.l5x5	16.9156	Yes	Yes	1	5	9
65	G.H2.07	G.S3.08	10.6522	Yes	No	0	9	9
66	G.H2.07	G.s3h2.03	5.04033	Yes	No	1	9	9
67	G.s3h2.03	b.l9x6	6.13633	No	Yes	1	9	8
68	G.H2.03	G.H2.05	7.53078	No	No	0	9	8
69	G.H2.03	b.l13x6	3.04667	No	Yes	0	9	9
70	G.H2.04	G.H2.07	7.04422	No	Yes	0	9	9
71	G.H2.04	G.H3.08	6.05589	No	No	0	9	9
72	G.H2.05	b.l17x6	7.51922	No	Yes	0	8	9
73	G.H2.06	b.l9x6	3.23611	Yes	Yes	1	9	8
74	G.H2.06	b.b14x1	9.536	Yes	No	1	9	8
75	G.H2.06	b.l15x1	3.987	Yes	Yes	1	9	7
76	G.H2.06	b.l17x6	9.25067	Yes	Yes	1	9	9
77	G.H2.06	b.b18x1	6.20333	Yes	No	1	9	9
78	G.H2.06	b.l19x1	4.85544	Yes	Yes	1	9	9
79	G.H2.07	G.h2s4.01	4.032	Yes	Yes	0	9	9
80	G.H2.07	b.l9x6	4.72722	Yes	Yes	1	9	8
81	G.H2.08	G.H3.18	5.11644	No	Yes	0	8	9
82	G.H2.09	G.H3.17	11.4341	No	Yes	1	8	5
83	G.H2.09	b.l27x1	3.65967	No	Yes	1	8	9
84	G.H2.10	b.b2x1	5.43556	Yes	Yes	1	7	8
85	G.H2.10	b.b6x1	3.168	Yes	Yes	1	7	9
86	G.h2s4.01	b.l5x5	13.83	Yes	Yes	0	9	9
87	G.H3.17	G.h2s4.02	4.41122	Yes	No	1	5	7
88	G.h2s4.02	b.l1x6	7.48155	No	Yes	1	7	9
89	G.h2s4.02	b.l27x1	5.74356	No	Yes	1	7	9
90	G.h2s4.04	G.h3s5.03	3.44933	No	No	0	9	7
91	G.H3.18	G.S4.02	5.63911	Yes	Yes	3	9	8
92	G.S4.02	G.h3s5.03	4.82533	Yes	No	3	8	7
93	G.S4.02	G.S5.02	4.15856	Yes	No	3	8	6
94	G.S4.03	G.S5.03	4.138	Yes	Yes	5	7	8
95	G.S4.03	G.S5.05	3.06811	Yes	Yes	5	7	9
96	G.H5.07	G.S4.03	4.00533	No	Yes	5	8	7
97	G.S4.04	G.S4.06	3.01344	Yes	No	0	9	7
98	G.H3.08	G.S4.04	5.47378	No	Yes	0	9	9
99	G.H3.09	G.S4.04	9.71689	Yes	Yes	3	9	9
100	G.S4.04	G.S5.04	3.15322	Yes	Yes	3	9	9
101	G.S4.05	G.S5.07	5.23711	Yes	Yes	5	7	9
102	G.H3.05	G.S4.06	4.17267	No	No	0	9	7
103	G.H4.15	G.S4.06	7.12111	Yes	No	0	8	7
104	G.S4.07	G.s4h3.03	4.75467	No	No	0	8	8
105	G.S4.07	G.s5hg.01	11.0967	No	No	0	8	9
106	G.S5.06	G.s4h3.01	5.80956	No	Yes	0	8	7
107	G.HG.04	G.s4h3.01	7.15544	No	Yes	0	9	7
108	G.H4.11	G.s4h3.01	4.00344	No	Yes	0	7	7
109	G.HG.03	G.s4h3.02	4.57	Yes	No	0	6	9
110	G.HG.07	G.s4h3.02	3.417	No	No	0	9	9
111	G.H3.01	G.s4h3.03	7.11389	Yes	No	0	9	8
112	G.s4h3.04	G.s4h3.05	5.50411	Yes	No	20	8	9
113	G.HG.04	G.s4h3.04	3.47744	No	Yes	0	9	8
114	G.HG.07	G.s4h3.04	5.17556	No	Yes	20	9	8
115	G.HG.13	G.s4h3.04	3.08011	No	Yes	0	7	8
116	G.HG.15	G.s4h3.04	5.66833	No	Yes	0	7	8
117	G.hgh4.01	G.s4h3.04	3.77067	No	Yes	0	6	8
118	G.HG.07	G.s4h3.05	5.19689	No	No	20	9	9
119	G.H3.01	G.s4h3.06	3.199	Yes	No	0	9	8
120	G.H3.03	G.s4h3.15	3.82167	No	No	0	4	9
121	G.H3.02	G.hgh4.02	4.50678	No	Yes	0	8	7
122	G.H3.06	G.hgh4.02	3.644	Yes	Yes	3	6	7
123	G.H3.06	G.H4.14	3.164	Yes	Yes	3	6	5
124	G.H3.06	G.H4.15	9.977	Yes	Yes	3	6	8
125	G.H3.06	G.h4s6.01	3.61767	Yes	No	0	6	4
126	G.H3.09	G.H3.13	4.59433	Yes	Yes	3	9	5
127	G.H3.09	G.S5.02	5.06722	Yes	No	3	9	6
128	G.H3.09	G.S5.04	5.25289	Yes	Yes	3	9	9
129	G.H3.09	G.H4.15	6.70322	Yes	Yes	3	9	8
130	G.H3.09	G.h4s6.01	5.60956	Yes	No	0	9	4
131	G.H3.09	G.S6.01	3.973	Yes	No	0	9	5
132	G.H3.10	G.H3.14	4.57511	No	Yes	0	5	8
133	G.H3.12	G.H3.18	3.01911	No	Yes	0	8	9
134	G.H3.13	G.S5.02	4.16667	Yes	No	3	5	6
135	G.H3.13	G.h4s6.02	7.47911	Yes	No	0	5	8
136	G.H3.14	G.h4s6.03	4.99	Yes	No	0	8	5
137	G.H3.15	G.H3.17	5.24822	No	Yes	0	8	5
138	G.H3.15	G.H3.18	8.53844	No	Yes	0	8	9
139	G.H3.16	G.H3.17	14.7902	No	Yes	0	4	5
140	G.H3.17	b.l25x6	11.174	Yes	Yes	1	5	8
141	G.H3.17	b.l27x1	4.37422	Yes	Yes	1	5	9
142	G.H3.18	G.h3s5.03	5.21511	Yes	No	3	9	7
143	G.h3s5.01	G.h4s6.04	3.06133	No	No	0	3	4
144	G.S5.01	G.S6.02	3.98667	No	Yes	11	7	7
145	G.H5.14	G.S5.01	7.07022	No	No	11	7	7
146	G.S5.03	G.S5.05	3.62978	Yes	Yes	5	8	9
147	G.H5.10	G.S5.03	6.46422	No	Yes	0	6	8
148	G.S5.04	G.S5.06	3.337	Yes	No	0	9	8
149	G.H4.15	G.S5.04	6.94244	Yes	Yes	3	8	9
150	G.S5.04	G.S6.03	3.48789	Yes	No	3	9	5
151	G.S5.05	G.S6.04	6.26178	Yes	No	0	9	9
152	G.S5.05	G.s6h5.01	6.01033	Yes	Yes	5	9	9
153	G.H5.03	G.S5.05	5.88144	Yes	Yes	5	8	9
154	G.H5.07	G.S5.05	3.82244	No	Yes	5	8	9
155	G.S5.06	G.S6.05	5.61444	No	Yes	0	8	4
156	G.S5.07	G.s5hg.01	3.40622	Yes	No	0	9	9
157	G.S5.07	G.s6h5.01	5.50867	Yes	Yes	5	9	9
158	G.HG.03	G.s5hg.01	4.44933	Yes	No	0	6	9
159	G.HG.01	G.S6.05	7.26378	No	Yes	3	5	4
160	G.HG.04	G.HG.08	3.17711	No	No	0	9	6
161	G.HG.15	G.hgh4.02	3.52778	No	Yes	0	7	7
162	G.HG.15	G.hgh4.05	9.27678	No	Yes	0	7	7
163	G.hgh4.01	G.hgh4.02	6.85011	No	Yes	0	6	7
164	G.H4.10	G.hgh4.02	6.39389	Yes	Yes	3	6	7
165	G.H4.14	G.hgh4.02	5.21622	Yes	Yes	3	5	7
166	G.H4.10	G.hgh4.05	15.0563	Yes	Yes	0	6	7
167	G.H4.05	G.hgh4.08	3.91711	No	Yes	0	4	3
168	G.H4.07	G.S6.05	10.2179	No	Yes	3	5	4
169	G.H4.10	G.H4.14	11.2154	Yes	Yes	3	6	5
170	G.H4.12	G.H4.16	6.95567	Yes	No	3	5	3
171	G.H4.12	G.S6.03	9.31867	Yes	No	3	5	5
172	G.H4.12	G.S6.05	4.06844	Yes	Yes	3	5	4
173	G.H4.14	G.H4.17	6.73056	Yes	No	0	5	4
174	G.H4.16	G.S6.03	4.76467	No	No	3	3	5
175	G.S6.01	G.h4s6.02	5.95711	No	No	0	5	8
176	G.H5.10	G.S6.02	9.81633	No	Yes	0	6	7
177	G.H5.13	G.S6.02	7.98144	Yes	Yes	11	8	7
178	G.H5.14	G.S6.02	6.39356	No	Yes	11	7	7
179	G.H5.17	G.S6.02	7.91211	Yes	Yes	11	5	7
180	G.H5.06	G.S6.04	19.4082	No	No	0	3	9
181	G.H5.03	G.s6h5.01	8.17222	Yes	Yes	5	8	9
182	G.H5.05	G.H5.09	6.08233	No	No	0	5	4
183	G.H5.08	G.H5.12	4.95644	Yes	No	0	8	6
184	G.H5.13	G.H5.17	6.47056	Yes	Yes	11	8	5
185	5x68	G.H5.13	10.1422	No	Yes	11	8	8
186	5x71	G.H5.13	3.60044	No	Yes	0	6	8
187	G.H5.15	G.H5.19	4.70111	Yes	No	6	7	8
188	G.H5.15	I2x51	3.26633	Yes	Yes	6	7	6
189	G.H5.15	I2x54	7.00622	Yes	No	0	7	7
190	G.H5.16	I2x50	5.36611	No	No	0	6	9
191	5x68	G.H5.16	8.41533	No	No	0	8	6
192	G.H5.17	G.H5.26	4.228	Yes	Yes	0	5	5
193	5x68	G.H5.17	7.336	No	Yes	11	8	5
194	3x53	G.H5.19	3.07678	No	No	6	8	8
195	G.H5.19	I2x53	7.67011	No	Yes	6	8	8
196	G.H5.20	G.H5.25	4.08956	Yes	Yes	0	9	7
197	G.H5.20	G.H5.26	7.04189	Yes	Yes	0	9	5
198	3x54	G.H5.20	4.34933	No	Yes	0	8	9
199	2x37	G.H5.22	3.08967	No	No	0	8	4
200	2x39	G.H5.23	3.32911	Yes	No	0	8	4
201	3x50	G.H5.23	10.8532	Yes	No	0	9	4
202	8x47	G.H5.24	3.08622	No	No	0	9	8
203	3x50	G.H5.25	3.30522	Yes	Yes	0	9	7
204	6x29	G.H5.26	8.08656	No	Yes	0	7	5
205	b.1x1	b.1x5	5.87111	Yes	No	0	4	3
206	b.1x2	b.1x5	3.51978	No	No	0	1	3
207	b.1x4	g.h1x4	4.15133	No	No	0	8	5
208	b.1x4	g.h1x5	3.54756	No	Yes	0	8	6
209	b.1x7	g.h1x8	6.05367	No	No	0	8	7
210	b.1x11	g.h1x11	5.36667	No	Yes	0	8	9
211	b.1x11	g.h1x12	3.27433	No	No	0	8	6
212	b.1x12	g.h1x11	3.36833	No	Yes	0	6	9
213	b.1x15	b.1x19	5.49822	Yes	No	0	7	6
214	b.1x18	g.l1x4	3.67289	No	Yes	0	4	8
215	b.1x19	b.b21x1	10.9471	No	Yes	0	6	7
216	b.1x19	b.b21x2	4.36156	No	No	0	6	6
217	b.1x22	g.l1x4	3.23522	No	Yes	0	3	8
218	b.b21x2	b.lh12x1	3.90889	No	No	0	6	3
219	b.lh12x2	g.h2x2	6.52633	No	No	0	8	9
220	b.h2x2	b.lh12x4	3.982	No	No	0	1	3
221	b.h2x3	b.lh12x4	7.39989	No	No	0	1	3
222	b.h2x1	b.h2x5	3.40844	Yes	No	0	5	5
223	b.b21x4	b.h2x1	3.82767	No	Yes	0	5	5
224	b.b21x5	b.h2x1	7.273	No	Yes	0	4	5
225	b.h2x1	g.h2x5	2.97922	Yes	No	0	5	6
226	b.b21x5	b.h2x2	3.27111	No	No	0	4	1
227	b.h2x4	g.h2x5	3.35356	No	No	0	3	6
228	b.h2x5	b.lhb1x3	3.20889	No	Yes	0	5	2
229	b.h2x5	b.l24x2	4.37478	No	Yes	0	5	6
230	b.l22x5	b.lhb1x3	3.77178	Yes	Yes	0	9	2
231	b.l24x3	b.lhb1x3	3.45756	Yes	Yes	0	5	2
232	b.lhb1x3	g.h2x9	4.06578	Yes	No	0	2	4
233	b.lhb1x4	b.lhb1x5	3.64933	No	No	0	1	1
234	b.l24x3	b.lhb1x5	3.94078	Yes	No	0	5	1
235	b.l22x5	b.lhb1x6	6.40922	Yes	Yes	12	9	3
236	b.b24x7	b.lhb1x6	7.75467	No	Yes	12	9	3
237	b.lhb1x10	b.lhb1x8	4.50444	No	No	0	4	2
238	b.lhb1x11	b.lhb1x9	3.20867	No	No	0	4	3
239	b.b23x1	b.lhb1x9	3.20222	No	No	0	5	3
240	b.b25x7	b.lhb1x11	5.38678	No	No	0	7	4
241	b.lhb1x11	g.ctx5	4.09722	No	No	0	4	9
242	b.b1x1	b.b1x3	4.00378	No	No	0	5	7
243	b.b1x2	b.b28x4	7.30689	No	Yes	10	3	6
244	b.b1x2	b.b28x6	9.06967	No	Yes	10	3	9
245	b.b1x3	b.b28x7	6.56222	No	No	0	7	9
246	b.b1x4	b.b5x1	3.13267	Yes	No	0	7	5
247	b.b1x4	b.b28x5	3.74611	Yes	No	14	7	5
248	b.b1x4	g.ctx16	5.35778	Yes	Yes	14	7	8
249	b.b1x5	b.l1x1	8.89644	No	No	0	3	7
250	b.b1x5	b.b28x4	9.876	No	Yes	0	3	6
251	b.b1x6	b.b4x6	20.3733	Yes	Yes	0	9	9
252	b.b1x6	b.b5x1	4.06044	Yes	No	0	9	5
253	b.b1x6	b.b28x3	5.50533	Yes	Yes	0	9	7
254	b.b1x6	b.b28x5	3.41078	Yes	No	0	9	5
255	b.b28x2	b.l1x1	6.02011	Yes	No	10	4	7
256	b.l1x3	b.l1x7	9.56044	Yes	No	0	9	9
257	b.b3x4	b.l1x3	6.61578	No	Yes	7	9	9
258	b.b3x6	b.l1x3	12.398	No	Yes	7	9	9
259	b.b4x4	b.l1x3	12.4348	No	Yes	7	8	9
260	b.b4x6	b.l1x3	4.22056	Yes	Yes	7	9	9
261	b.l1x4	b.l3x2	6.90722	No	Yes	0	6	9
262	b.l1x5	b.l3x2	3.48189	No	Yes	0	7	9
263	b.l1x6	b.l3x1	6.59822	Yes	Yes	1	9	9
264	b.l1x6	b.l27x1	21.8022	Yes	Yes	1	9	9
265	b.b28x3	b.l1x7	3.12167	Yes	No	0	7	9
266	b.b2x1	b.l3x1	11.923	Yes	Yes	1	8	9
267	b.b2x1	b.b6x1	3.87222	Yes	Yes	1	8	9
268	b.b2x3	b.b2x5	4.27689	No	Yes	7	6	7
269	b.b2x3	b.b3x2	3.79733	No	No	7	6	5
270	b.b26x2	b.b2x3	4.734	No	No	0	7	6
271	b.b10x4	b.b2x4	13.8168	No	No	0	6	6
272	b.b2x5	b.b3x2	12.4647	Yes	No	7	7	5
273	b.b2x5	b.l4x1	5.13244	Yes	No	0	7	5
274	b.b2x5	b.l26x1	12.7896	Yes	No	7	7	7
275	b.b27x2	b.b2x5	4.48222	No	Yes	0	5	7
276	b.b6x5	b.l2x1	4.54089	Yes	No	0	6	5
277	b.l26x2	b.l2x2	3.37378	No	No	0	1	1
278	b.l2x3	b.l2x5	3.38556	No	No	0	8	5
279	b.b3x1	b.l2x3	6.12289	No	No	0	5	8
280	b.l26x1	b.l2x4	7.35356	No	No	7	7	5
281	b.l26x3	b.l2x4	10.6026	No	No	7	7	5
282	b.b4x7	b.l2x5	15.0584	No	No	0	8	5
283	b.l2x5	b.l4x2	25.8269	No	No	0	5	4
284	b.b3x1	b.b6x5	4.662	No	Yes	0	5	6
285	b.b3x2	b.b4x6	5.32867	No	Yes	7	5	9
286	b.b3x3	b.b4x3	3.80778	Yes	Yes	9	8	7
287	b.b3x3	b.b4x5	3.51511	Yes	Yes	9	8	7
288	b.b3x3	b.b6x3	4.213	Yes	No	0	8	8
289	b.b3x3	b.b6x5	5.08967	Yes	Yes	9	8	6
290	b.b3x3	b.b7x2	3.58167	Yes	Yes	9	8	8
291	b.b3x4	b.b4x6	6.13589	No	Yes	7	9	9
292	b.b28x3	b.b3x4	4.70411	Yes	No	0	7	9
293	b.b3x5	b.l5x6	3.39089	No	No	0	9	9
294	b.b3x5	b.b6x3	3.45	No	No	0	9	8
295	b.b3x6	b.l3x2	9.04789	No	Yes	7	9	9
296	b.l3x1	b.l5x5	7.93444	Yes	Yes	1	9	9
297	b.b4x2	b.l3x2	6.19233	No	Yes	0	8	9
298	b.b4x1	b.l5x1	3.724	No	Yes	0	8	8
299	b.b4x3	b.b5x7	4.36144	Yes	Yes	0	7	7
300	b.b4x3	b.l5x1	5.01511	Yes	Yes	9	7	8
301	b.b4x3	b.b7x2	3.31111	Yes	Yes	9	7	8
302	b.b4x3	b.b7x4	3.91244	Yes	No	9	7	8
303	b.b4x4	b.b4x6	14.5099	No	Yes	7	8	9
304	b.b4x4	b.b5x3	3.92667	No	Yes	7	8	9
305	b.b4x5	b.b5x4	3.80589	Yes	No	9	7	5
306	b.b4x5	b.b5x5	7.11522	Yes	Yes	9	7	5
307	b.b4x5	b.l8x1	4.24822	Yes	Yes	9	7	5
308	b.b4x6	b.b5x3	11.1747	Yes	Yes	7	9	9
309	b.b4x7	b.l4x3	9.95656	No	No	0	8	6
310	b.l4x1	g.ctx16	5.82633	No	Yes	0	5	8
311	b.l4x2	g.ctx15	13.2761	No	Yes	14	4	9
312	b.l4x2	g.ctx16	6.55622	No	Yes	14	4	8
313	b.b5x2	b.l4x3	10.3181	Yes	No	0	7	6
314	b.b5x4	b.b5x5	5.67533	No	Yes	9	5	5
315	b.b5x5	b.l8x8	6.10522	Yes	No	0	5	4
316	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
317	b.b5x7	b.b8x4	7.65533	Yes	Yes	0	7	6
318	b.b5x7	b.l8x8	7.20244	Yes	No	0	7	4
319	b.l5x1	b.l5x6	4.15544	Yes	No	9	8	9
320	b.b7x4	b.l5x1	4.63656	No	Yes	9	8	8
321	b.b8x4	b.l5x1	5.093	Yes	Yes	0	6	8
322	b.l5x2	b.l8x10	3.648	No	No	21	6	4
323	b.b9x3	b.l5x2	7.74189	Yes	No	21	6	6
324	b.l5x3	b.l7x3	8.50545	No	No	0	8	9
325	b.l5x4	b.l5x5	6.727	No	Yes	0	8	9
326	b.l5x5	b.l7x2	5.40478	Yes	Yes	1	9	9
327	b.b7x4	b.l5x6	3.19078	No	No	9	8	9
328	b.b6x1	b.l7x1	4.32756	Yes	No	0	9	9
329	b.b10x2	b.b6x2	3.17344	No	No	0	6	8
330	b.b10x3	b.b6x2	4.732	No	No	0	8	8
331	b.b6x5	b.l6x4	4.60311	Yes	No	0	6	5
332	b.b6x5	b.l8x1	3.36156	Yes	Yes	9	6	5
333	b.b10x5	b.l6x1	7.02678	Yes	No	0	9	6
334	b.l6x3	b.l6x5	9.46978	No	Yes	19	6	4
335	b.l10x3	b.l6x3	8.07844	No	No	19	6	6
336	b.b7x1	b.l6x5	3.51511	Yes	Yes	19	4	4
337	b.l6x5	b.l8x2	6.233	Yes	No	0	4	4
338	b.l10x3	b.l6x5	6.85367	No	Yes	19	6	4
339	b.b7x1	b.b8x5	11.2169	Yes	No	0	4	4
340	b.b7x1	b.l10x3	7.78144	Yes	No	19	4	6
341	b.b7x2	b.l8x1	4.98322	Yes	Yes	9	8	5
342	b.b10x5	b.b7x3	3.63489	Yes	No	0	9	9
343	b.b7x5	b.l9x7	3.268	No	No	0	9	7
344	b.l7x3	b.l7x5	4.97756	No	No	0	9	6
345	b.b11x4	b.b8x1	3.30489	Yes	No	0	9	8
346	b.b8x2	b.b8x4	5.42822	No	Yes	0	8	6
347	b.b8x2	b.b9x3	3.12856	No	Yes	0	8	6
348	b.b8x3	b.b9x4	3.04322	Yes	Yes	0	6	9
349	b.b8x3	b.l12x1	5.06956	Yes	No	0	6	6
350	b.b8x4	b.l8x10	5.82	Yes	No	0	6	4
351	b.b8x5	b.l8x3	4.67911	No	No	0	4	3
352	b.l8x1	b.l8x8	3.37733	Yes	No	0	5	4
353	b.l8x3	b.l8x9	3.30656	No	No	0	3	3
354	b.l8x5	b.l8x7	2.993	No	No	0	3	3
355	b.b9x3	b.l8x10	3.01156	Yes	No	21	6	4
356	b.b13x1	b.b9x2	4.18433	No	No	0	4	5
357	b.b12x6	b.b9x4	18.828	Yes	Yes	0	8	9
358	b.l9x3	b.l9x7	5.48478	Yes	No	1	9	7
359	b.b11x4	b.l9x3	6.16478	Yes	Yes	1	9	9
360	b.b11x6	b.l9x3	14.227	No	Yes	1	9	9
361	b.l11x2	b.l9x3	9.89011	Yes	Yes	1	9	9
362	b.b12x6	b.l9x3	6.53478	Yes	Yes	1	8	9
363	b.l11x2	b.l9x4	7.13289	Yes	No	0	9	5
364	b.l11x1	b.l9x6	6.35778	No	Yes	1	9	8
365	b.l13x6	b.l9x6	8.53067	Yes	Yes	1	9	8
366	b.b14x1	b.l9x6	3.75089	No	Yes	1	8	8
367	b.b11x4	b.l9x7	3.37289	Yes	No	1	9	7
368	b.b10x1	b.b11x5	4.564	No	No	0	9	6
369	b.b10x2	b.b14x3	6.455	No	Yes	0	6	5
370	b.b10x4	b.b14x5	3.05056	No	No	0	6	5
371	b.b10x5	b.b11x2	10.5356	Yes	No	0	9	7
372	b.b11x1	b.l10x1	4.61133	No	Yes	0	5	3
373	b.b14x5	b.l10x1	6.13633	No	Yes	0	5	3
374	b.b11x1	b.l10x2	7.90367	No	No	0	5	5
375	b.b12x7	b.l10x4	8.13933	Yes	No	22	9	3
376	b.l10x4	b.l12x2	5.15567	No	No	22	3	6
377	b.b11x1	b.b12x5	6.43056	No	No	0	5	6
378	b.b11x2	b.l12x1	3.77767	No	No	0	7	6
379	b.b11x3	b.b14x3	4.15544	No	Yes	8	5	5
380	b.b11x3	b.b15x1	5.82489	No	Yes	8	5	9
381	b.b11x4	b.b12x6	8.98833	Yes	Yes	1	9	8
382	b.b11x5	b.l13x7	5.79856	No	Yes	0	6	9
383	b.b11x5	b.b14x3	5.52067	No	Yes	0	6	5
384	b.b11x6	b.l11x1	3.09333	No	No	1	9	9
385	b.b11x6	b.l11x2	9.53944	No	Yes	1	9	9
386	b.l11x1	b.l13x6	5.18044	No	Yes	1	9	9
387	b.b12x2	b.l11x2	10.312	No	Yes	0	7	9
388	b.b12x3	b.b13x7	4.22111	Yes	Yes	8	8	7
389	b.b12x3	b.l13x7	3.88922	Yes	Yes	8	8	9
390	b.b12x3	b.b15x1	3.77244	Yes	Yes	8	8	9
391	b.b12x3	b.b15x3	3.21067	Yes	Yes	8	8	9
392	b.b12x4	b.b12x6	4.16467	No	Yes	1	4	8
393	b.b12x4	b.b13x3	5.87711	No	No	1	4	4
394	b.b12x5	b.b13x4	3.30578	No	No	0	6	4
395	b.b12x5	b.b13x5	3.14344	No	No	0	6	4
396	b.b12x6	b.b13x3	14.4459	Yes	No	1	8	4
397	b.b12x7	b.l12x2	3.06222	Yes	No	22	9	6
398	b.b12x7	b.l12x3	9.47644	Yes	No	0	9	5
399	b.b13x2	b.l12x3	5.82356	No	No	0	4	5
400	b.b13x3	b.b13x6	5.59056	No	No	0	4	4
401	b.b13x5	b.b13x7	7.24989	No	Yes	0	4	7
402	b.b13x7	b.b15x1	12.0982	Yes	Yes	8	7	9
403	b.b13x7	b.b16x6	15.8231	Yes	Yes	8	7	8
404	b.b13x7	b.b17x1	3.81556	Yes	No	0	7	4
405	b.l13x3	b.l13x7	6.89056	Yes	Yes	8	9	9
406	b.b15x3	b.l13x3	5.91967	Yes	Yes	8	9	9
407	b.b15x5	b.l13x3	8.03267	No	Yes	8	8	9
408	b.l13x3	b.l15x2	7.449	Yes	Yes	8	9	9
409	b.b16x4	b.l13x3	13.7696	Yes	Yes	8	6	9
410	b.b16x6	b.l13x3	5.06589	Yes	Yes	8	8	9
411	b.l13x4	b.l15x2	6.84267	No	Yes	0	3	9
412	b.l13x5	b.l15x2	3.18556	No	Yes	0	5	9
413	b.l13x6	b.l15x1	3.82111	Yes	Yes	1	9	7
414	b.b15x3	b.l13x7	3.19422	Yes	Yes	8	9	9
415	b.b15x5	b.l13x7	3.22322	No	Yes	8	8	9
416	b.b14x1	b.l15x1	3.276	No	Yes	1	8	7
417	b.b14x2	b.b18x3	4.62367	No	Yes	0	7	8
418	b.b14x3	b.b15x1	4.357	Yes	Yes	8	5	9
419	b.b14x4	b.b18x5	5.69589	No	No	0	8	5
420	b.b18x5	b.l14x1	5.36333	No	No	0	5	4
421	b.l14x2	b.l18x4	3.72167	No	No	0	4	7
422	b.l14x3	b.l14x5	6.49989	No	No	0	5	5
423	b.l14x5	b.l16x2	7.55733	No	No	0	5	9
424	b.b16x5	b.l14x6	6.09167	Yes	No	0	5	3
425	b.b16x7	b.l14x6	3.08956	Yes	No	0	9	3
426	b.b15x1	b.b16x6	14.2986	Yes	Yes	8	9	8
427	b.b15x2	b.b16x5	2.98	Yes	Yes	0	6	5
428	b.b15x2	b.b18x3	5.80156	Yes	Yes	4	6	8
429	b.b15x2	b.b18x5	8.46255	Yes	No	0	6	5
430	b.b15x2	b.b19x2	10.617	Yes	Yes	4	6	6
431	b.b15x3	b.b16x6	6.17778	Yes	Yes	8	9	8
432	b.b15x4	b.l17x7	3.83956	No	No	0	6	7
433	b.b15x5	b.l15x2	3.72111	No	Yes	8	8	9
434	b.l15x1	b.l17x6	9.545	Yes	Yes	1	7	9
435	b.b16x2	b.l15x2	8.72044	No	Yes	0	5	9
436	b.b16x4	b.b16x6	9.44756	Yes	Yes	8	6	8
437	b.b16x4	b.b17x3	7.09611	Yes	No	8	6	5
438	b.b16x4	b.b17x6	13.3627	Yes	No	0	6	7
439	b.b16x5	b.l20x1	6.32033	Yes	No	0	5	6
440	b.b16x6	b.b17x3	5.80278	Yes	No	8	8	5
441	b.b16x7	b.l16x3	11.7092	Yes	No	23	9	3
442	b.b16x7	b.b17x4	9.02433	Yes	No	23	9	5
443	b.b17x2	b.l16x3	4.76733	No	No	0	3	3
444	b.b17x4	b.l16x3	4.93544	No	No	23	5	3
445	b.b17x3	g.h1x10	4.83189	No	No	0	5	9
446	b.b17x5	b.b17x7	7.23844	Yes	Yes	4	7	8
447	b.b17x5	b.b21x1	12.9509	Yes	Yes	4	7	7
448	b.b17x5	g.l1x2	3.26278	Yes	No	0	7	2
449	b.b17x6	g.h1x14	8.37533	No	No	0	7	9
450	b.b17x7	b.b19x2	12.0628	Yes	Yes	4	8	6
451	b.b17x7	b.b20x6	11.5278	Yes	Yes	4	8	6
452	b.b17x7	b.b21x1	3.74267	Yes	Yes	4	8	7
453	b.l17x3	b.l17x7	9.48689	Yes	No	4	9	7
454	b.b19x4	b.l17x3	9.14033	Yes	Yes	4	8	9
455	b.b19x6	b.l17x3	12.6313	No	Yes	4	9	9
456	b.b20x4	b.l17x3	18.8816	Yes	Yes	4	8	9
457	b.l17x4	b.l19x2	6.28089	No	Yes	0	3	9
458	b.l17x5	b.l19x2	4.66011	No	Yes	0	6	9
459	b.l17x6	b.l19x1	6.99211	Yes	Yes	1	9	9
460	b.b19x4	b.l17x7	3.81689	Yes	No	4	8	7
461	b.b18x1	b.l19x1	10.7401	No	Yes	1	9	9
462	b.b18x3	b.b19x2	5.20222	Yes	Yes	4	8	6
463	b.b18x3	b.b19x4	4.408	Yes	Yes	4	8	8
464	b.b18x4	b.b22x5	3.259	No	Yes	0	3	7
465	b.l18x1	b.l18x2	8.74833	Yes	Yes	13	6	7
466	b.l18x1	b.l18x3	4.27144	Yes	No	13	6	5
467	b.b22x5	b.l18x1	8.92044	Yes	Yes	13	7	6
468	b.l18x1	b.l22x4	4.31822	Yes	No	13	6	9
469	b.l18x1	g.h2x8	7.11844	Yes	No	0	6	7
470	b.l18x1	g.h2x11	5.43244	Yes	Yes	13	6	6
471	b.b22x5	b.l18x2	4.60578	Yes	Yes	13	7	7
472	b.l18x2	b.l22x4	4.06	Yes	No	13	7	9
473	b.l18x2	g.h2x11	4.89589	Yes	Yes	13	7	6
474	b.l18x3	b.l18x5	8.14311	No	No	0	5	2
475	b.l18x3	g.h2x11	16.0486	No	Yes	13	5	6
476	b.l18x5	b.l20x2	10.4987	No	Yes	0	2	9
477	b.b19x2	b.b20x6	11.5036	Yes	Yes	4	6	6
478	b.b19x3	b.b22x5	3.10978	No	Yes	13	4	7
479	b.b19x3	b.b23x2	3.16933	No	Yes	13	4	6
480	b.b19x4	b.b20x6	7.03522	Yes	Yes	4	8	6
481	b.b19x5	b.l21x9	4.56511	No	No	0	5	6
482	b.b20x2	b.l19x2	9.73267	Yes	Yes	4	6	9
483	b.b20x2	b.b20x4	9.01111	Yes	Yes	4	6	8
484	b.b20x2	b.b21x6	3.01789	Yes	No	4	6	1
485	b.b20x2	b.l21x1	3.71489	Yes	No	0	6	2
486	b.b20x3	b.b21x7	4.195	No	Yes	0	8	5
487	b.b20x3	b.l21x9	4.74622	No	No	0	8	6
488	b.b20x4	b.b20x6	4.087	Yes	Yes	4	8	6
489	b.b20x4	b.b21x3	14.9911	Yes	Yes	4	8	6
490	b.b20x4	b.b21x6	7.22889	Yes	No	4	8	1
491	b.b20x5	b.b21x4	5.04322	No	No	0	7	5
492	b.b20x5	b.b21x7	5.964	No	Yes	0	7	5
493	b.b20x6	b.b21x3	5.05122	Yes	Yes	4	6	6
494	b.b20x7	b.l20x3	4.52711	Yes	No	0	9	7
495	b.b20x7	b.b21x4	8.09856	Yes	No	0	9	5
496	b.b20x7	g.h2x4	4.58067	Yes	No	0	9	7
497	b.l20x2	g.l1x5	7.48889	Yes	No	0	9	4
498	b.l20x2	g.h2x7	7.585	Yes	No	0	9	5
499	b.b21x1	g.l1x4	11.8706	Yes	Yes	0	7	8
500	b.b21x2	g.h2x1	3.90033	No	No	0	6	8
501	b.b21x3	b.b21x6	4.67267	Yes	No	4	6	1
502	b.b21x5	b.b21x7	8.062	No	Yes	0	4	5
503	b.b21x7	b.b23x2	6.37156	Yes	Yes	0	5	6
504	b.b21x7	b.b24x6	11.1124	Yes	Yes	0	5	8
505	b.b21x7	b.b25x1	3.57278	Yes	No	0	5	2
506	b.l21x2	b.l21x4	8.29078	No	No	0	4	4
507	b.b23x6	b.l21x5	5.06411	Yes	No	0	7	4
508	b.l21x7	b.l23x1	3.82033	No	Yes	0	5	6
509	b.l21x7	b.l23x2	6.172	No	No	0	5	8
510	b.l21x8	b.l23x1	3.42622	No	Yes	0	4	6
511	b.b23x6	b.l21x9	9.49522	Yes	No	0	7	6
512	b.b22x1	b.b22x2	4.60444	No	No	0	8	8
513	b.b22x2	b.b26x3	6.17233	No	No	0	8	6
514	b.b22x4	b.b26x5	4.09578	No	No	0	5	7
515	b.b22x5	b.b23x2	9.40544	Yes	Yes	13	7	6
516	b.b23x1	b.l22x1	4.70511	No	No	0	5	9
517	b.l22x1	g.ctx3	8.16056	No	Yes	0	9	9
518	b.l22x1	g.ctx5	3.91956	No	No	0	9	9
519	b.l22x2	g.ctx3	3.48978	No	Yes	0	1	9
520	b.l22x3	g.ctx3	9.20867	No	Yes	12	9	9
521	b.l22x3	g.ctx6	3.001	No	Yes	12	9	6
522	b.b24x7	b.l22x5	13.0211	No	Yes	12	9	9
523	b.l22x5	b.l24x2	9.206	Yes	Yes	12	9	6
524	b.l22x5	g.h2x12	3.823	Yes	No	12	9	7
525	b.l22x5	g.ctx6	5.15478	Yes	Yes	12	9	6
526	b.b23x1	b.b24x5	5.08256	No	No	0	5	5
527	b.b23x3	b.b24x5	4.63556	No	No	0	7	5
528	b.b23x3	b.b27x1	4.56933	No	No	0	7	6
529	b.b23x4	b.b23x6	4.52178	No	Yes	0	6	7
530	b.b23x5	b.l25x7	3.20978	No	No	0	7	7
531	b.b23x6	b.l23x2	3.00278	Yes	No	0	7	8
532	b.b23x6	b.b24x4	14.2138	Yes	Yes	16	7	6
533	b.b23x6	b.b24x6	6.79489	Yes	Yes	16	7	8
534	b.l23x1	b.l25x6	13.6446	Yes	Yes	1	6	8
535	b.b24x2	b.l23x2	6.47878	No	No	0	5	8
536	b.b24x1	b.l25x5	2.98011	No	No	0	4	7
537	b.b24x2	b.b25x6	4.28356	No	Yes	16	5	3
538	b.b24x3	b.b25x7	6.80867	No	No	0	5	7
539	b.b24x4	b.b24x6	4.10567	Yes	Yes	16	6	8
540	b.b24x4	b.b25x3	9.58978	Yes	Yes	16	6	5
541	b.b24x4	b.b25x6	3.26856	Yes	Yes	16	6	3
542	b.b24x6	b.b25x3	6.54356	Yes	Yes	16	8	5
543	b.b24x7	b.l24x3	11.275	No	Yes	0	9	5
544	b.l24x2	g.h2x9	3.67367	Yes	No	0	6	4
545	b.l24x2	g.h2x12	5.52033	Yes	No	12	6	7
546	b.b25x2	b.l24x3	4.96267	No	Yes	0	2	5
547	b.b25x3	b.b25x6	3.09678	Yes	Yes	16	5	3
548	b.b25x7	b.b28x6	19.956	No	Yes	0	7	9
549	b.l25x3	b.l25x7	4.35178	Yes	No	0	9	7
550	b.b27x3	b.l25x3	7.075	No	Yes	0	8	9
551	b.b27x5	b.l25x3	13.7473	No	Yes	10	9	9
552	b.l25x3	b.l27x2	8.26489	Yes	Yes	10	9	9
553	b.b28x4	b.l25x3	8.93711	Yes	Yes	10	6	9
554	b.l25x4	b.l27x2	4.81778	No	Yes	0	5	9
555	I1x48	b.l25x4	4.50167	Yes	No	0	8	5
556	b.l25x5	b.l27x1	5.96389	No	Yes	0	7	9
557	b.l25x6	b.l27x1	22.3354	Yes	Yes	1	8	9
558	b.b26x1	b.b26x2	3.956	No	No	0	9	7
559	b.b26x1	b.l27x1	4.81956	No	Yes	0	9	9
560	b.b26x3	b.b27x3	3.96311	No	No	0	6	8
561	b.b26x5	b.b27x1	3.42311	No	No	0	7	6
562	b.l26x1	b.l26x3	6.87511	No	No	7	7	7
563	b.l26x3	b.l26x5	6.56	No	No	0	7	5
564	b.l26x5	g.ctx4	5.758	No	No	0	5	7
565	b.l26x5	g.ctx15	6.39089	No	Yes	0	5	9
566	b.l26x6	g.ctx16	4.77589	No	Yes	0	7	8
567	b.b27x1	b.b28x6	3.01222	No	Yes	0	6	9
568	b.b27x3	b.b28x6	7.762	No	Yes	0	8	9
569	b.b27x5	b.l27x2	9.73511	No	Yes	10	9	9
570	b.b28x2	b.l27x2	8.99811	Yes	Yes	10	4	9
571	b.b28x4	b.b28x6	5.15556	Yes	Yes	10	6	9
572	b.b28x5	g.ctx16	3.94989	No	Yes	14	5	8
573	b.b28x7	g.ctx14	9.30878	No	No	14	9	9
574	b.b28x7	g.ctx16	3.99944	No	Yes	14	9	8
575	g.h1x1	g.h1x5	3.95367	No	Yes	0	2	6
576	g.h2x11	g.h2x15	18.5004	Yes	No	0	6	6
577	g.ctx2	g.h2x15	6.60544	No	No	0	3	6
578	g.ctx3	g.ctx4	4.23967	Yes	No	0	9	7
579	g.ctx3	g.ctx6	5.89622	Yes	Yes	12	9	6
580	g.ctx13	g.ctx9	5.05389	No	No	0	5	6
581	g.ctx10	g.ctx13	10.2181	No	No	0	5	5
582	g.ctx14	g.ctx15	5.97667	No	Yes	14	9	9
583	g.ctx14	g.ctx16	5.74444	No	Yes	14	9	8
584	1x36	2x65	2.99478	No	No	0	7	6
585	1x39	2x61	4.11944	No	No	0	7	8
586	1x39	7x39	9.46522	No	Yes	0	7	8
587	1x43	2x57	5.19	No	No	0	8	9
588	1x46	1x50	2.98244	Yes	Yes	0	8	9
589	1x46	2x54	3.17533	Yes	No	0	8	8
590	1x46	2x57	3.74567	Yes	No	0	8	9
591	1x46	7x46	3.03278	Yes	No	0	8	9
592	1x46	7x47	3.72933	Yes	No	0	8	7
593	1x49	7x50	3.11267	No	No	0	9	9
594	1x50	2x47	3.61267	Yes	No	0	9	9
595	1x50	2x50	10.9641	Yes	Yes	0	9	9
596	1x50	2x51	3.66222	Yes	No	0	9	8
597	1x50	7x50	9.55678	Yes	No	0	9	9
598	1x53	2x47	3.39333	No	No	0	9	9
599	1x53	7x54	3.32489	No	No	0	9	8
600	1x57	2x44	6.29911	No	No	0	8	7
601	1x59	8x57	4.28389	No	No	0	7	8
602	1x60	I1x50	6.56078	Yes	Yes	15	8	9
603	1x60	8x53	3.80456	Yes	No	15	8	9
604	I1x48	I1x51	3.90089	Yes	No	0	8	8
605	8x49	I1x50	3.21478	No	Yes	0	7	9
606	8x50	I1x50	10.4351	Yes	Yes	15	9	9
607	8x53	I1x50	3.06889	No	Yes	15	9	9
608	2x37	2x40	6.58622	No	No	0	8	9
609	2x38	4x42	3.24333	Yes	No	0	7	7
610	2x39	3x49	4.57811	Yes	No	6	8	8
611	2x39	I2x53	5.25722	Yes	Yes	6	8	8
612	2x40	8x50	7.692	No	Yes	0	9	9
613	2x42	3x45	3.78944	Yes	No	0	8	7
614	2x42	3x46	3.18089	Yes	No	0	8	9
615	2x42	3x49	9.04133	Yes	No	0	8	8
616	2x42	4x45	4.42	Yes	No	0	8	8
617	2x42	4x46	4.29689	Yes	No	0	8	9
618	2x45	3x42	7.71489	No	No	0	9	8
619	2x45	4x46	6.48422	No	No	0	9	9
620	2x45	4x50	4.83422	No	No	0	9	9
621	2x46	2x50	4.07089	Yes	Yes	2	9	9
622	2x46	3x42	4.74511	Yes	No	0	9	8
623	2x46	3x43	4.92244	Yes	Yes	2	9	8
624	2x46	7x49	8.48222	Yes	Yes	2	9	9
625	2x46	7x53	3.16644	Yes	Yes	2	9	9
626	2x49	3x39	3.283	No	No	0	8	9
627	2x49	4x50	3.32711	No	No	0	8	9
628	2x50	3x39	4.64667	Yes	No	0	9	9
629	2x50	7x46	10.1436	Yes	No	0	9	9
630	2x50	7x49	7.65856	Yes	Yes	2	9	9
631	2x52	3x35	5.53533	No	No	0	7	7
632	2x53	3x35	3.91756	No	No	0	8	7
633	2x53	7x42	3.17822	No	Yes	0	8	8
634	2x55	2x551	3.36089	No	No	0	6	5
635	2x551	3x31	7.72067	No	No	0	5	6
636	2x56	3x28	3.02444	No	Yes	0	8	7
637	2x56	3x32	6.68378	No	No	2	8	8
638	2x56	7x42	3.80633	No	Yes	2	8	8
639	2x57	7x42	7.75644	No	Yes	0	9	8
640	2x59	3x24	6.058	No	No	0	6	6
641	2x59	3x28	7.31267	No	Yes	0	6	7
642	2x60	3x28	3.65367	Yes	Yes	0	8	7
643	2x60	7x39	6.06811	Yes	Yes	2	8	8
644	2x60	7x42	6.94511	Yes	Yes	2	8	8
645	2x62	2x66	4.56867	No	No	0	6	5
646	2x64	7x35	6.50944	Yes	No	0	7	6
647	2x64	7x39	5.13511	Yes	Yes	2	7	8
648	E1x49	E1x51	4.35533	No	No	0	4	4
649	E1x50	E1x52	9.30911	Yes	Yes	18	9	7
650	3x24	E1x50	3.66444	No	Yes	18	6	9
651	3x25	E1x50	6.03522	No	Yes	18	9	9
652	3x28	E1x50	5.53056	Yes	Yes	0	7	9
653	E1x50	E2x50	9.96922	Yes	No	18	9	9
654	3x24	E1x52	4.951	No	Yes	18	6	7
655	3x25	E2x50	7.23956	No	No	18	9	9
656	3x26	E2	5.75222	No	Yes	17	6	5
657	3x27	3x31	3.05956	No	No	0	6	6
658	3x29	4x61	3.14389	No	Yes	0	6	8
659	3x29	E2x52	3.54778	No	No	0	6	7
660	3x30	4x61	3.991	No	Yes	0	8	8
661	3x30	4x62	5.33756	No	No	0	8	7
662	3x32	7x42	8.807	No	Yes	2	8	8
663	3x32	Lig	15.008	No	Yes	2	8	0
664	3x33	4x57	4.67611	No	No	0	8	9
665	3x33	Lig	11.1441	No	Yes	0	8	0
666	3x34	4x53	2.98378	No	No	0	7	8
667	3x34	4x54	4.69822	No	No	0	7	6
668	3x34	4x57	3.679	No	No	0	7	9
669	3x36	6x48	4.26756	No	Yes	0	8	9
670	3x36	Lig	6.00422	No	Yes	0	8	0
671	3x37	4x53	4.192	No	No	0	8	8
672	3x37	4x56	3.40733	No	No	2	8	8
673	3x37	5x461	8.84511	No	No	2	8	8
674	3x38	4x50	6.21011	No	No	0	8	9
675	3x38	4x53	3.094	No	No	0	8	8
676	3x40	5x50	3.20111	No	Yes	0	9	9
677	3x40	6x44	3.351	No	Yes	2	9	9
678	3x40	6x48	12.7369	No	Yes	2	9	9
679	3x41	4x49	3.54533	No	No	0	8	9
680	3x41	4x52	5.21511	No	No	0	8	7
681	3x41	5x50	3.598	No	Yes	0	8	9
682	3x42	4x49	5.24267	No	No	0	8	9
683	3x43	6x44	3.62722	Yes	Yes	2	8	9
684	3x43	7x53	6.12122	Yes	Yes	2	8	9
685	3x44	5x50	3.81178	No	Yes	0	7	9
686	3x44	5x53	4.03889	No	No	0	7	8
687	3x46	3x50	5.37233	No	Yes	2	9	9
688	3x46	7x53	5.90856	No	Yes	2	9	9
689	3x47	5x54	7.49233	No	No	0	9	9
690	3x47	5x57	4.22433	No	No	0	9	7
691	3x47	5x58	10.5143	No	Yes	0	9	9
692	3x49	I2x53	8.44211	No	Yes	6	8	8
693	3x50	5x58	6.766	Yes	Yes	0	9	9
694	3x50	7x53	5.73644	Yes	Yes	2	9	9
695	3x51	3x55	10.7361	Yes	No	0	8	8
696	3x51	5x57	4.601	Yes	No	0	8	7
697	3x51	5x60	8.33	Yes	No	0	8	7
698	3x51	5x61	4.33056	Yes	No	0	8	9
699	3x52	I2x53	4.08844	No	Yes	0	6	8
700	3x52	4x41	5.43967	No	No	0	6	8
701	3x53	I2x53	8.42267	No	Yes	6	8	8
702	3x54	5x61	3.21378	No	No	0	8	9
703	3x54	5x64	3.56689	No	No	0	8	7
704	3x56	I2x52	5.33644	No	No	0	6	6
705	4x56	5x461	3.51767	No	No	2	8	8
706	4x59	4x60	3.09733	No	No	0	6	8
707	4x60	E2	3.13822	No	Yes	17	8	5
708	4x60	5x39	7.45344	No	Yes	17	8	8
709	4x61	5x39	4.44	Yes	Yes	17	8	8
710	5x36	E2	5.75678	No	Yes	17	7	5
711	E2	E2	17.2069	Yes	Yes	17	5	5
712	E2	E2x51	8.68145	Yes	No	0	5	5
713	E2x52	Lig	4.59844	No	Yes	0	7	0
714	5x36	5x39	4.08244	No	Yes	17	7	8
715	5x39	5x43	11.3743	Yes	No	0	8	9
716	5x40	6x55	7.28756	No	Yes	0	7	8
717	5x43	Lig	6.76822	No	Yes	0	9	0
718	5x44	6x52	5.66378	No	Yes	0	8	8
719	5x461	Lig	4.26989	No	Yes	2	8	0
720	5x47	5x48	8.46267	Yes	No	0	9	7
721	5x47	5x51	10.6916	Yes	No	2	9	7
722	5x47	6x44	5.16911	Yes	Yes	2	9	9
723	5x47	6x48	3.52022	Yes	Yes	2	9	9
724	5x47	6x49	4.48422	Yes	Yes	0	9	7
725	5x47	6x52	22.3854	Yes	Yes	2	9	8
726	5x48	6x56	5.07378	No	No	0	7	7
727	5x49	5x50	3.484	No	Yes	0	8	9
728	5x51	6x44	5.78856	No	Yes	2	7	9
729	5x55	6x41	3.26244	No	No	0	6	8
730	5x56	5x60	3.01644	No	No	0	5	7
731	5x58	6x37	5.16856	Yes	No	0	9	8
732	5x58	6x40	5.84889	Yes	No	0	9	9
733	5x58	6x41	4.92856	Yes	No	0	9	8
734	5x62	5x66	11.496	No	No	0	7	6
735	5x62	6x34	7.29356	No	No	0	7	8
736	5x66	5x70	5.03944	No	No	0	6	7
737	5x69	6x30	5.47356	No	No	0	6	9
738	6x36	7x56	5.55333	No	No	0	9	8
739	6x40	7x53	4.94667	No	Yes	0	9	9
740	6x44	6x48	5.83544	Yes	Yes	2	9	9
741	6x47	7x45	8.46744	No	No	0	9	9
742	6x48	6x52	6.20289	Yes	Yes	2	9	8
743	6x48	7x41	6.25367	Yes	No	0	9	8
744	6x48	7x45	11.2623	Yes	No	0	9	9
745	6x49	6x50	3.27378	Yes	No	0	7	9
746	6x49	6x53	3.28422	Yes	No	0	7	7
747	6x50	7x37	5.30144	No	No	0	9	5
748	6x51	7x34	3.18789	Yes	No	0	8	5
749	6x51	7x38	4.69889	Yes	No	2	8	8
750	6x51	Lig	14.2882	Yes	Yes	2	8	0
751	6x52	Lig	7.93622	Yes	Yes	2	8	0
752	6x54	7x37	6.50722	No	No	0	5	5
753	6x55	Lig	6.97822	Yes	Yes	2	8	0
754	6x58	E3	6.14533	No	Yes	0	5	4
755	6x58	7x34	4.91511	No	No	0	5	5
756	6x61	E3	7.85267	No	Yes	0	6	4
757	7x33	7x37	3.85211	No	No	0	6	5
758	7x38	7x42	4.63411	No	Yes	2	8	8
759	7x38	Lig	5.979	No	Yes	2	8	0
760	7x39	7x42	5.30744	Yes	Yes	2	8	8
761	7x42	Lig	8.90333	Yes	Yes	2	8	0
762	7x45	7x49	9.98933	No	Yes	0	9	9
763	7x51	7x55	3.01844	No	No	0	7	7
764	7x52	7x53	5.29311	No	Yes	0	8	9
765	7x54	8x50	9.46667	No	Yes	15	8	9
766	7x54	8x54	3.73611	No	Yes	15	8	9
767	8x47	8x50	5.84011	No	Yes	0	9	9
768	8x50	8x54	5.43089	Yes	Yes	15	9	9
769	G.H1.01	G.s1h1.05	3.043	Yes	No	5	9	9
770	G.S4.05	G.s1h1.05	3.26489	Yes	No	5	7	9
771	G.s3h2.03	b.l7x4	5.96933	No	Yes	0	9	9
772	G.H2.10	b.l7x2	3.70278	Yes	Yes	1	7	9
773	G.h2s4.01	G.h2s4.04	3.44967	Yes	No	0	9	9
774	G.HG.01	G.s4h3.01	3.34278	No	Yes	0	5	7
775	G.hgh4.01	G.s4h3.15	10.3332	No	No	0	6	9
776	G.H3.02	G.H4.11	3.39167	No	No	0	8	7
777	G.H3.13	G.H3.14	4.14056	Yes	Yes	0	5	8
778	G.H4.03	G.HG.05	7.79267	No	No	0	4	5
779	G.HG.16	G.hgh4.05	4.12744	No	Yes	0	4	7
780	6x33	G.H5.25	3.07044	No	Yes	0	9	7
781	b.lh12x2	g.l1x6	8.52689	No	No	0	8	4
782	b.b2x1	b.l1x6	3.22411	Yes	Yes	1	8	9
783	b.b2x1	b.l27x1	5.40122	Yes	Yes	1	8	9
784	b.b6x1	b.l7x2	3.159	Yes	Yes	1	9	9
785	b.b6x1	b.l9x6	6.211	Yes	Yes	1	9	8
786	b.b6x5	b.b7x2	4.23544	Yes	Yes	9	6	8
787	b.b7x1	b.b8x3	3.21322	Yes	Yes	0	4	6
788	b.l7x4	b.l9x5	4.39322	Yes	No	0	9	8
789	b.b9x3	b.l7x5	3.09744	Yes	No	0	6	6
790	b.b8x1	b.b9x4	4.708	No	Yes	0	8	9
791	b.b10x5	b.b8x3	3.73911	Yes	Yes	0	9	6
792	b.l8x5	b.l8x9	5.19422	No	No	0	3	3
793	b.b16x5	b.b17x5	4.83256	Yes	Yes	0	5	7
794	b.l17x3	b.l19x2	5.56	Yes	Yes	4	9	9
795	b.b19x6	b.l19x2	6.52722	No	Yes	4	9	9
796	b.b20x7	b.l20x2	3.88933	Yes	Yes	0	9	9
797	b.b22x1	b.l25x6	5.89356	No	Yes	0	8	8
798	b.b24x2	b.b24x4	3.83033	No	Yes	16	5	6
799	b.b24x3	b.l25x7	3.13022	No	No	0	5	7
800	b.b28x1	b.b28x2	3.02267	No	Yes	0	4	4
801	g.h1x10	g.h1x14	3.90744	No	No	0	9	9
802	g.l1x2	g.l1x4	4.82967	No	Yes	0	2	8
803	g.ctx15	g.ctx16	4.687	Yes	Yes	14	9	8
804	1x52	8x54	4.305	No	Yes	0	8	9
805	1x56	8x54	3.38456	No	Yes	0	9	9
806	2x39	2x40	3.01989	Yes	No	0	8	9
807	2x53	7x46	3.38733	No	No	0	8	9
808	E1x51	E1x52	5.29133	No	Yes	0	4	7
809	3x43	7x49	5.90411	Yes	Yes	2	8	9
810	4x61	E2	5.75711	Yes	Yes	17	8	5
811	4x63	E2	5.71167	No	Yes	0	6	5
812	5x40	6x59	5.09411	No	No	0	7	6
813	5x54	6x44	6.49322	No	Yes	0	9	9
814	6x51	6x52	9.15789	Yes	Yes	2	8	8
815	6x51	6x55	9.14067	Yes	Yes	2	8	8
816	7x30	7x33	3.87833	No	No	0	6	6
817	G.H2.10	b.l3x1	4.512	Yes	Yes	1	7	9
818	G.H3.10	G.h4s6.01	3.85178	No	No	0	5	4
819	G.HG.02	G.HG.03	3.92044	No	Yes	0	9	6
820	G.HG.02	G.s6h5.02	5.04822	No	No	0	9	7
821	G.H4.05	G.hgh4.05	10.6364	No	Yes	0	4	7
822	G.H5.02	G.H5.06	3.09089	No	No	0	4	3
823	5x72	G.H5.13	4.922	No	Yes	11	5	8
824	g.h1x12	g.h1x9	3.42	No	No	0	6	6
825	b.1x15	g.l1x4	2.97911	Yes	Yes	0	7	8
826	I1x48	b.b28x2	3.58622	Yes	Yes	10	8	4
827	2x60	2x64	4.51133	Yes	Yes	2	8	7
828	4x64	E2	3.27956	No	Yes	0	7	5
829	5x39	E2	5.31111	Yes	Yes	17	8	5
830	5x36	5x38	3.166	No	No	0	7	5
831	5x37	6x60	3.91244	No	No	0	4	6
832	5x44	6x55	3.82422	No	Yes	0	8	8
833	5x66	6x30	4.00556	No	No	0	6	9
834	b.1x2	b.1x6	3.62711	No	No	0	1	3
835	b.l1x3	b.l3x2	3.864	Yes	Yes	7	9	9
836	b.l8x4	b.l8x5	3.10133	No	No	0	3	3
837	b.b25x3	b.l21x2	5.69333	Yes	No	0	5	4
838	G.H3.17	b.l23x1	4.31778	Yes	Yes	1	5	6
839	5x72	G.H5.17	4.80644	No	Yes	11	5	5
840	1x60	I1x49	3.62822	Yes	No	15	8	7
841	G.H4.12	G.H4.13	5.94711	Yes	Yes	0	5	3
842	G.H5.03	G.s6h5.05	3.68044	Yes	No	5	8	9
843	G.S1.03	G.hns1.01	11.3642	No	No	0	9	3
844	G.S1.02	I2x51	3.858	Yes	Yes	6	5	6
845	G.H3.01	G.s1h1.03	3.89267	Yes	No	0	9	8
846	G.H2.01	G.H2.03	4.78244	No	No	0	9	9
847	G.H2.01	b.b12x1	3.68	No	No	0	9	6
848	G.H2.09	b.l25x6	3.14044	No	Yes	1	8	8
849	G.h2s4.03	b.l1x6	4.608	No	Yes	0	5	9
850	G.H3.01	G.H3.04	5.402	Yes	No	0	9	9
851	G.H3.03	G.H3.07	4.78133	No	No	0	4	5
852	G.H3.13	G.h4s6.13	16.3853	Yes	No	0	5	0
853	G.H3.14	G.h4s6.08	3.04622	Yes	No	0	8	3
854	G.h3s5.01	G.h4s6.12	4.548	No	No	0	3	4
855	G.H4.07	G.HG.01	5.66533	No	No	3	5	5
856	G.hgh4.04	G.hgh4.07	3.12733	No	No	0	6	7
857	G.H4.10	G.hgh4.08	9.12222	Yes	Yes	0	6	3
858	G.H4.13	G.hgh4.08	5.94911	Yes	Yes	0	3	3
859	G.H4.08	G.hgh4.14	5.27778	Yes	No	0	3	0
860	G.hgh4.17	G.hgh4.20	4.73533	No	Yes	3	0	0
861	G.H4.07	G.hgh4.20	5.28	No	Yes	3	5	0
862	G.H4.01	G.hgh4.21	4.75844	No	No	0	3	0
863	G.H4.02	G.hgh4.21	6.51133	No	No	0	5	0
864	G.H4.08	G.H4.12	4.84644	Yes	Yes	3	3	5
865	G.H4.08	G.S6.05	6.35022	Yes	Yes	3	3	4
866	G.h4s6.10	G.h4s6.12	5.34822	No	No	0	3	4
867	G.H5.17	G.h4s6.20	5.74911	Yes	No	11	5	0
868	G.H5.10	G.S6.04	6.35756	No	No	0	6	9
869	G.s6h5.01	G.s6h5.05	3.56556	Yes	No	5	9	9
870	G.H5.08	I2x51	3.65467	Yes	Yes	6	8	6
871	7x55	8x51	3.64933	No	No	0	7	9
872	5x72	G.h4s6.20	4.62089	No	No	11	5	0
873	I1x48	b.l1x1	4.88022	Yes	No	10	8	7
874	I1x49	I1x50	3.37044	No	Yes	15	7	9
875	I2x53	I2x57	4.842	Yes	No	0	8	0
876	G.h4s6.11	G.h4s6.20	2.96156	No	No	0	7	0
877	1x42	1x46	2.95978	No	Yes	0	7	8
878	6x43	7x48	2.94	No	No	0	7	7
879	2x38	4x39	2.93578	Yes	No	0	7	6
880	G.H1.05	G.S2.04	2.92667	No	No	0	6	6
881	1x43	2x58	2.89744	No	No	0	8	9
882	G.HN.46	G.HN.50	2.87267	No	No	0	4	5
883	5x77	G.hgh4.13	2.85822	No	No	0	0	0
884	5x37	E3	2.858	No	Yes	0	4	4
885	G.S4.01	G.S5.03	2.85156	No	Yes	0	8	8
886	2x62	E1x52	2.84389	No	Yes	0	6	7
887	G.H5.17	G.h4s6.12	2.835	Yes	No	0	5	4
888	b.l10x1	b.l16x1	2.831	Yes	No	0	3	4
889	b.b27x4	b.b28x3	2.831	No	Yes	0	5	7
890	G.HN.11	G.HN.33	2.80467	No	No	0	2	4
891	6x43	7x52	2.80011	No	No	0	7	8
892	G.H4.04	G.hgh4.16	2.79956	No	No	0	4	0
893	2x52	2x551	2.79656	No	No	0	7	5
894	G.H1.09	G.S2.04	2.78756	No	No	0	7	6
895	G.h4s6.09	G.h4s6.10	2.785	No	No	0	3	3
896	G.hgh4.08	G.hgh4.11	2.78	Yes	No	0	3	0
897	G.S2.04	G.S3.05	2.77911	No	Yes	0	6	7
898	b.1x1	g.h1x1	2.77422	Yes	No	0	4	2
899	b.b16x3	b.b19x2	2.77	No	Yes	0	6	6
900	5x76	G.h4s6.03	2.76	No	No	0	0	5
901	6x45	6x49	2.74689	No	Yes	0	7	7
902	6x39	7x52	2.74311	No	No	0	8	8
903	b.b10x3	b.b11x4	2.74156	No	Yes	0	8	9
904	3x22	E2	2.73878	No	Yes	0	3	5
905	1x48	1x52	2.71733	No	No	0	5	8
906	b.b19x1	g.h2x8	2.71433	No	No	0	6	7
907	b.b16x7	b.l16x2	2.71122	Yes	No	0	9	9
908	b.l10x1	b.l14x4	2.70222	Yes	No	0	3	1
909	b.1x12	b.1x9	2.7	No	No	0	6	4
910	b.l17x5	b.l19x1	2.68022	No	Yes	0	6	9
911	1x60	8x56	2.66133	Yes	No	0	8	7
912	b.b18x2	b.b22x3	2.65722	No	No	0	5	6
913	2x41	4x42	2.63856	No	No	0	7	7
914	b.b21x3	b.l17x2	2.63756	Yes	No	0	6	6
915	b.1x15	g.h1x15	2.63422	Yes	No	0	7	8
916	g.ctx4	g.ctx9	2.63022	No	No	0	7	6
917	G.H5.22	I2x55	2.62	No	No	0	4	0
918	G.HN.51	G.hns1.02	2.61356	No	No	0	5	4
919	g.h2x3	g.h2x7	2.61222	No	No	0	5	5
920	b.b26x4	b.b2x5	2.59222	No	Yes	0	5	7
921	b.b7x1	b.b9x1	2.58567	Yes	No	0	4	4
922	5x41	6x60	2.56867	No	No	0	7	6
923	2x38	4x38	2.55833	Yes	No	0	7	6
924	b.b5x3	b.l1x2	2.55822	Yes	No	0	9	9
925	b.b10x5	b.b6x4	2.55578	Yes	No	0	9	7
926	b.1x4	g.h1x8	2.54956	No	No	0	8	7
927	g.h2x14	g.h2x15	2.53578	No	No	0	4	6
928	b.b12x7	b.b13x4	2.52444	Yes	No	0	9	4
929	3x23	3x26	2.522	No	No	0	4	6
930	2x38	I2x53	2.51567	Yes	Yes	0	7	8
931	b.lhb1x1	b.lhb1x2	2.51311	No	No	0	1	1
932	b.b12x2	b.l13x1	2.512	No	No	0	7	2
933	6x36	G.H5.25	2.50333	No	Yes	0	9	7
934	G.HG.14	G.HG.16	2.50267	Yes	No	0	5	4
935	G.HN.43	b.b5x6	2.48822	No	No	0	9	6
936	b.l22x2	b.l26x4	2.47789	No	No	0	1	9
937	b.1x13	b.1x16	2.46556	Yes	No	0	1	4
938	G.HN.42	G.HN.45	2.43467	No	No	0	4	4
939	G.HG.09	G.hgh4.21	2.412	No	No	0	2	0
940	G.H4.03	G.HG.08	2.39778	No	No	0	4	6
941	3x55	3x56	2.36067	No	No	0	8	6
942	2x63	E1x50	2.33822	No	Yes	0	7	9
943	G.H2.04	G.H3.11	2.32867	No	No	0	9	7
944	1x55	8x57	2.30544	No	No	0	5	8
945	G.HG.14	G.HG.17	2.30378	Yes	No	0	5	3
946	G.H1.11	G.H5.04	2.27733	No	No	0	0	7
947	G.HN.39	b.b5x5	2.25633	No	Yes	0	5	5
948	5x59	5x63	2.24322	No	No	0	4	5
949	b.b22x3	b.b23x2	2.235	No	Yes	0	6	6
950	6x32	G.H5.26	2.224	No	Yes	0	9	5
951	4x56	5x46	2.22356	No	No	0	8	6
952	1x47	2x54	2.22111	No	No	0	7	8
953	b.b28x6	b.l25x2	2.21689	Yes	No	0	9	5
954	b.1x11	b.1x7	2.20922	No	No	0	8	8
955	g.ctx7	g.ctx8	2.19722	No	No	0	4	8
956	g.h1x11	g.h1x7	2.18356	Yes	No	0	9	2
957	G.HN.37	G.HN.41	2.17222	No	No	0	3	4
958	G.h3s5.01	G.h3s5.02	2.12733	No	No	0	3	4
959	3x30	4x58	2.12533	No	No	0	8	0
960	G.H4.01	G.HG.14	2.11833	No	Yes	0	3	5
961	5x65	G.H5.20	2.10722	No	Yes	0	8	9
962	3x48	4x45	2.10644	No	No	0	7	8
963	G.hgh4.10	G.hgh4.11	2.1	No	No	0	0	0
964	b.b25x4	b.lhb1x6	2.09278	No	Yes	0	4	3
965	2x48	2x52	2.091	No	No	0	7	7
966	b.b1x3	g.ctx17	2.08511	No	No	0	7	7
967	G.H4.17	G.hgh4.04	2.06778	No	No	0	4	6
968	G.H2.02	b.l13x6	2.06067	No	Yes	0	8	9
969	5x63	5x67	2.05233	No	No	0	5	6
970	b.lh12x2	b.lh12x3	2.02289	No	No	0	8	4
971	b.1x13	b.1x17	2.02	Yes	No	0	1	2
972	5x83	G.H4.17	2.00756	No	No	0	0	4
973	G.H4.06	G.HG.08	1.99356	No	No	0	7	6
974	6x57	E3	1.98933	No	Yes	0	7	4
975	b.b10x5	b.l6x2	1.98633	Yes	No	0	9	6
976	b.h2x4	g.h2x2	1.97789	No	No	0	3	9
977	b.b1x1	g.ctx18	1.977	No	No	0	5	6
978	b.ntx3	g.h1x5	1.95122	No	Yes	0	0	6
979	b.b17x2	g.h1x13	1.90889	No	No	0	3	1
980	b.b24x5	b.b25x5	1.90133	No	No	0	5	4
981	6x27	6x30	1.90111	No	No	0	5	9
982	5x79	G.h4s6.03	1.90067	No	No	0	0	5
983	5x62	6x37	1.885	No	No	0	7	8
984	G.H4.04	G.hgh4.20	1.88067	No	Yes	0	4	0
985	2x43	7x53	1.88	No	Yes	0	8	9
986	1x57	8x50	1.87767	No	Yes	0	8	9
987	b.l7x5	b.l9x1	1.87378	No	No	0	6	5
988	b.l14x1	b.l14x2	1.87	No	No	0	4	4
989	1x31	7x32	1.87	No	No	0	0	4
990	b.1x13	b.1x9	1.86956	Yes	No	0	1	4
991	g.ctx6	g.ctx7	1.86556	Yes	No	0	6	4
992	7x30	7x32	1.86333	No	No	0	6	4
993	b.b23x2	b.l24x1	1.85689	Yes	No	0	6	5
994	b.1x1	g.ntx4	1.83533	Yes	No	0	4	0
995	G.H4.12	G.hgh4.13	1.82711	Yes	No	0	5	0
996	G.hgh4.17	G.hgh4.18	1.81444	No	No	0	0	0
997	G.H1.03	G.s6h5.03	1.81333	No	No	0	9	9
998	b.b2x2	b.b6x3	1.80933	No	No	0	7	8
999	5x45	5x48	1.78689	No	No	0	6	7
1000	G.S2.02	G.S3.07	1.77867	No	No	0	5	9
1001	g.h1x6	g.h1x9	1.77	No	No	0	4	6
1002	b.l2x2	b.l6x2	1.75	No	No	0	1	6
1003	1x51	2x51	1.747	No	No	0	6	8
1004	G.HG.16	G.hgh4.06	1.74289	No	No	0	4	3
1005	7x55	7x56	1.739	No	No	0	7	8
1006	G.S5.07	G.s6h5.03	1.72178	Yes	No	0	9	9
1007	4x40	I2	1.71333	No	No	0	6	0
1008	G.H5.21	G.H5.26	1.70311	No	Yes	0	5	5
1009	G.HN.52	I2	1.69933	No	No	0	4	0
1010	b.b12x6	b.l9x2	1.67422	Yes	No	0	8	5
1011	g.ctx11	g.ctx17	1.674	No	No	0	4	7
1012	b.b13x1	b.b9x4	1.672	No	Yes	0	4	9
1013	g.ctx12	g.ctx13	1.662	No	No	0	6	5
1014	1x42	7x43	1.64156	No	No	0	7	6
1015	5x51	5x52	1.633	No	No	0	7	4
1016	7x30	7x31	1.62267	No	No	0	6	3
1017	5x75	G.H4.16	1.6	No	No	0	0	3
1018	b.1x8	g.h1x8	1.58644	No	No	0	5	7
1019	8x49	8x52	1.56967	No	No	0	7	6
1020	g.ctx6	g.h2x16	1.54489	Yes	No	0	6	4
1021	5x82	G.H4.13	1.54356	No	Yes	0	0	3
1022	1x45	7x47	1.519	No	No	0	5	7
1023	G.HG.12	G.HG.14	1.49978	No	Yes	0	1	5
1024	5x74	G.hgh4.13	1.48644	No	No	0	5	0
1025	6x50	7x40	1.47667	No	No	0	9	8
1026	6x35	6x39	1.46178	No	No	0	8	8
1027	b.b16x2	b.l17x1	1.45778	No	No	0	5	2
1028	2x41	4x43	1.45311	No	No	0	7	5
1029	G.hgh4.02	G.hgh4.03	1.45222	Yes	No	0	7	5
1030	I2x52	I2x56	1.44356	No	No	0	6	0
1031	b.b16x4	b.l13x2	1.43333	Yes	No	0	6	6
1032	b.l8x3	b.l8x6	1.41556	No	No	0	3	4
1033	G.s1h1.02	G.s1h1.05	1.406	No	No	0	7	9
1034	b.b25x5	b.lhb1x8	1.40067	No	No	0	4	2
1035	1x38	1x39	1.381	No	No	0	5	7
1036	b.1x3	b.1x7	1.35878	No	No	0	1	8
1037	1x35	2x64	1.35633	No	Yes	0	5	7
1038	G.H5.02	G.s6h5.04	1.351	No	No	0	4	8
1039	G.HN.29	G.HN.33	1.32356	Yes	No	0	0	4
1040	b.b25x6	b.l25x1	1.32222	Yes	No	0	3	3
1041	b.1x16	b.1x20	1.32067	No	No	0	4	2
1042	G.S2.02	G.s3h2.01	1.30556	No	No	0	5	9
1043	3x21	3x23	1.29533	No	No	0	8	4
1044	b.1x14	g.h1x15	1.28289	No	No	0	4	8
1045	1x59	1x60	1.262	No	Yes	0	7	8
1046	8x52	8x55	1.24	No	No	0	6	5
1047	G.HN.11	G.HN.34	1.222	No	No	0	2	3
1048	G.H4.08	G.hgh4.15	1.22178	Yes	No	0	3	0
1049	G.H5.14	G.H5.18	1.21144	No	No	0	7	4
1050	1x54	2x47	1.20667	No	No	0	7	9
1051	G.s4h3.08	G.s4h3.10	1.193	No	No	0	8	9
1052	b.1x15	g.h1x11	1.18922	Yes	Yes	0	7	9
1053	5x55	5x59	1.18589	No	No	0	6	4
1054	4x44	4x48	1.18578	No	No	0	3	4
1055	G.HN.53	G.hns1.03	1.15533	No	No	0	1	4
1056	4x51	4x55	1.13733	No	No	0	5	5
1057	b.b16x1	b.l17x3	1.13556	No	Yes	0	4	9
1058	4x34	4x37	1.119	No	No	0	7	8
1059	G.HN.45	G.HN.49	1.09711	No	No	0	4	4
1060	G.H1.01	G.H1.02	1.06133	Yes	No	0	9	9
1061	b.1x10	b.1x13	1.056	No	Yes	0	1	1
1062	b.b20x1	b.l21x5	1.04656	No	No	0	5	4
1063	b.lhb1x6	b.lhb1x7	1.04267	Yes	No	0	3	1
1064	G.HN.44	G.HN.48	1.03189	No	No	0	6	3
1065	4x36	G.HN.48	1.029	No	No	0	8	3
1066	8x48	8x52	1.01767	No	No	0	5	6
1067	6x27	6x31	1.01211	No	No	0	5	7
1068	b.lhb1x2	b.lhb1x3	1.00756	No	Yes	0	1	2
1069	1x30	NT	0.988222	No	No	0	0	0
1070	1x32	1x35	0.972	No	No	0	6	5
1071	G.HN.31	G.HN.32	0.964	No	No	0	1	5
1072	g.ctx1	g.ctx2	0.96	No	No	0	1	3
1073	G.HG.03	G.HG.06	0.959	Yes	No	0	6	5
1074	G.HN.30	G.HN.32	0.958	No	No	0	7	5
1075	G.HN.46	G.HN.49	0.952333	No	No	0	4	4
1076	G.HN.27	G.HN.29	0.952	No	Yes	0	0	0
1077	G.hfs2.03	G.hfs2.05	0.952	No	No	0	0	0
1078	4x40	4x44	0.939	No	No	0	6	3
1079	b.ntx2	g.h1x5	0.93	No	Yes	0	5	6
1080	5x78	G.H4.13	0.925333	No	Yes	0	0	3
1081	1x33	1x37	0.889333	No	No	0	7	6
1082	G.H1.06	G.H1.10	0.887333	No	No	0	9	8
1083	7x36	7x40	0.844222	No	No	0	6	8
1084	2x67	E1	0.844	No	No	0	5	0
1085	1x40	1x44	0.841333	No	No	0	4	5
1086	2x63	E1	0.828	No	No	0	7	0
1087	G.H1.12	G.S2.07	0.822	No	No	0	0	3
1088	G.s4h3.08	G.s4h3.11	0.815	No	No	0	8	8
1089	2x61	2x65	0.8	No	No	0	8	6
1090	1x34	1x35	0.793333	No	No	0	5	5
1091	b.lhb1x3	g.h2x13	0.790667	Yes	No	0	2	1
1092	1x32	NT	0.776667	No	No	0	6	0
1093	G.H5.01	G.s6h5.04	0.753	No	No	0	9	8
1094	G.hns1.03	I2x55	0.738222	No	No	0	4	0
1095	G.s3h2.02	b.l7x4	0.728	No	Yes	0	9	9
1096	G.H1.10	G.H1.11	0.726	No	No	0	8	0
1097	G.s4h3.07	G.s4h3.14	0.709333	No	No	0	5	6
1098	4x55	4x59	0.698444	No	No	0	5	6
1099	G.H3.04	G.s4h3.08	0.683	No	No	0	9	8
1100	6x41	6x42	0.671	No	No	0	8	7
1101	6x28	6x31	0.665	No	No	0	6	7
1102	G.s4h3.11	G.s4h3.13	0.65	No	No	0	8	4
1103	4x34	G.hns1.03	0.647	No	No	0	7	4
1104	g.ntx2	g.ntx4	0.64	No	No	0	4	0
1105	5x81	G.hgh4.09	0.639333	No	No	0	0	0
1106	G.s2s3.02	I2x55	0.605333	No	No	0	3	0
1107	b.l21x6	b.l21x7	0.601333	No	No	0	3	5
1108	G.HN.10	G.HN.11	0.59	No	No	0	0	2
1109	1x40	2x61	0.57	No	No	0	4	8
1110	b.l21x2	b.l21x3	0.546	No	No	0	4	3
1111	1x52	8x58	0.537667	No	No	0	8	8
1112	5x41	5x42	0.529333	No	No	0	7	7
1113	g.h1x1	g.ntx1	0.524222	No	No	0	2	3
1114	G.HN.34	G.HN.37	0.495333	No	No	0	3	3
1115	g.h1x2	g.h1x5	0.491778	No	Yes	0	2	6
1116	5x69	5x73	0.491667	No	No	0	6	5
1117	b.h2x4	g.h2x6	0.486	No	No	0	3	2
1118	I2x57	I2x58	0.485333	No	No	0	0	0
1119	G.HG.10	G.HG.12	0.464667	No	No	0	0	1
1120	G.s4h3.07	G.s4h3.12	0.428	No	No	0	5	4
1121	4x47	4x51	0.424667	No	No	0	5	5
1122	g.h1x12	g.l1x1	0.404444	No	No	0	6	1
1123	b.1x1	g.ntx3	0.383556	Yes	No	0	4	4
1124	5x77	5x81	0.376222	No	No	0	0	0
1125	1x37	1x41	0.368444	No	No	0	6	6
1126	g.h1x3	g.ntx3	0.368222	No	No	0	3	4
1127	1x37	1x38	0.368	No	No	0	6	5
1128	G.s4h3.13	G.s4h3.14	0.346556	No	No	0	4	6
1129	6x37	6x38	0.328	No	No	0	8	8
1130	G.hfs2.03	G.hfs2.06	0.324	No	No	0	0	7
1131	6x26	6x27	0.323111	No	No	0	0	5
1132	g.l1x2	g.l1x3	0.311111	No	No	0	2	1
1133	2x37	I1x52	0.272	No	No	0	8	0
1134	6x46	6x47	0.268444	No	No	0	5	9
1135	b.ntx1	b.ntx2	0.268	No	No	0	5	5
1136	G.HN.28	G.HN.29	0.261111	No	Yes	0	0	0
1137	8x55	CT	0.254222	No	No	0	5	0
1138	5x86	G.hgh4.04	0.226444	No	No	0	0	6
1139	8x60	8x61	0.179111	No	No	0	0	0
1140	G.S2.02	G.h1ha.01	0.174889	No	No	0	5	0
1141	b.b1x4	g.ctx19	0.165333	Yes	No	0	7	0
1142	5x80	5x84	0.164444	No	No	0	0	0
1143	G.HN.26	G.HN.29	0.157556	No	Yes	0	0	0
1144	G.HN.38	G.HN.42	0.15	No	No	0	3	4
1145	G.S2.03	G.h1ha.02	0.146	Yes	No	0	9	0
1146	1x57	1x58	0.136889	No	No	0	8	6
1147	8x58	8x59	0.114	No	No	0	8	0
1148	8x55	8x61	0.0848889	No	No	0	5	0
1149	G.HN.35	G.HN.38	0.0671111	No	No	0	4	3
1150	5x81	G.hgh4.12	0.0546667	No	No	0	0	0
1151	5x85	G.hgh4.09	0.0375556	No	No	0	0	0
1152	G.hgh4.17	G.hgh4.19	0.0364444	No	No	3	0	0
1153	G.hgh4.19	G.hgh4.20	0.0364444	No	Yes	3	0	0
1154	g.h2x10	g.h2x9	0.0357778	No	No	0	3	4
1155	5x76	5x80	0.0317778	No	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.S1.02	5.00164	5	6	5
2	G.S1.06	5.19858	4	5	8
3	G.H1.01	4.25428	6	5	9
4	G.S2.03	5.63083	4	1	9
5	G.S2.08	6.89433	4	6	5
6	G.S3.01	5.01956	4	6	4
7	G.S3.03	6.66293	6	6	7
8	G.S3.04	7.94656	4	1	6
9	G.S3.05	4.23103	4	0	7
10	G.S3.06	8.52583	4	1	5
11	G.H2.06	6.17809	6	1	9
12	G.H2.07	6.2992	5	1	9
13	G.H2.10	4.20458	4	1	7
14	G.h2s4.01	9.34375	4	0	9
15	G.S4.02	4.99561	4	3	8
16	G.S4.03	3.81151	5	5	7
17	G.S4.04	5.33933	4	3	9
18	G.S4.05	3.77558	4	5	7
19	G.s4h3.01	5.07781	4	0	7
20	G.s4h3.04	4.44604	6	20	8
21	G.H3.01	5.55902	5	0	9
22	G.H3.06	5.10067	4	3	6
23	G.H3.09	5.8453	7	3	9
24	G.H3.13	7.3532	5	3	5
25	G.H3.14	4.18797	4	0	8
26	G.H3.17	7.96425	7	1	5
27	G.H3.18	5.50564	5	3	9
28	G.S5.03	4.27089	4	5	8
29	G.S5.04	4.43469	5	3	9
30	G.S5.05	4.73019	7	5	9
31	G.S5.07	4.01563	6	5	9
32	G.HG.03	3.47469	4	0	6
33	G.HG.14	2.10614	4	0	5
34	G.hgh4.02	4.513	7	3	7
35	G.hgh4.05	9.77425	4	0	7
36	G.hgh4.08	5.44211	4	0	3
37	G.H4.08	4.42406	4	3	3
38	G.H4.10	10.447	4	3	6
39	G.H4.12	5.49391	6	3	5
40	G.H4.13	3.59128	4	0	3
41	G.H4.14	6.58156	4	3	5
42	G.H4.15	7.68594	4	3	8
43	G.S6.02	7.21802	5	11	7
44	G.S6.05	6.70296	5	3	4
45	G.s6h5.01	5.81419	4	5	9
46	G.H5.03	5.18519	4	5	8
47	G.H5.08	5.25439	6	6	8
48	G.H5.13	6.62333	5	11	8
49	G.H5.15	4.50903	4	6	7
50	G.H5.17	5.6196	7	11	5
51	G.H5.20	4.397	4	0	9
52	G.H5.25	3.24214	4	0	7
53	G.H5.26	4.65671	5	0	5
54	b.1x1	2.71606	4	0	4
55	b.1x13	1.85278	4	0	1
56	b.1x15	3.07519	4	0	7
57	b.h2x1	4.37208	4	0	5
58	b.lhb1x3	2.71704	6	0	2
59	b.lhb1x6	4.32483	4	12	3
60	b.b1x4	3.10047	4	14	7
61	b.b1x6	8.33747	4	0	9
62	b.l1x3	8.18226	6	7	9
63	b.l1x6	8.74282	5	1	9
64	b.b2x1	5.97122	5	1	8
65	b.b2x5	6.95633	6	7	7
66	b.b3x3	4.04144	5	9	8
67	b.l3x1	7.74192	4	1	9
68	b.l3x2	5.89867	5	7	9
69	b.b4x3	4.08158	5	9	7
70	b.b4x5	4.67111	4	9	7
71	b.b4x6	10.2905	6	7	9
72	b.b5x2	6.53778	4	0	7
73	b.b5x3	6.55763	6	7	9
74	b.b5x5	5.28803	4	9	5
75	b.b5x7	5.65231	4	0	7
76	b.l5x1	4.52482	5	9	8
77	b.l5x5	9.16239	6	1	9
78	b.b6x1	4.14756	5	1	9
79	b.b6x5	4.41544	6	9	6
80	b.l6x5	6.51789	4	19	4
81	b.b7x1	5.66247	5	19	4
82	b.b7x2	4.02786	4	9	8
83	b.l7x2	3.97019	4	1	9
84	b.l7x4	3.70627	5	0	9
85	b.b8x3	3.76628	4	0	6
86	b.b8x4	5.99914	4	0	6
87	b.l8x1	3.99258	4	9	5
88	b.b9x3	4.24486	4	21	6
89	b.b9x4	7.06281	4	0	9
90	b.l9x3	8.46029	5	1	9
91	b.l9x6	5.56429	7	1	8
92	b.b10x5	4.91307	6	0	9
93	b.l10x1	4.07022	4	0	3
94	b.b11x4	4.91449	5	1	9
95	b.l11x2	9.21861	4	1	9
96	b.b12x3	3.77336	4	8	8
97	b.b12x6	9.10598	6	1	8
98	b.b12x7	5.80061	4	22	9
99	b.b13x7	8.64158	5	8	7
100	b.l13x3	7.85456	6	8	9
101	b.l13x6	4.52791	5	1	9
102	b.l13x7	4.59916	5	8	9
103	b.b14x3	5.12203	4	8	5
104	b.b15x1	8.07022	5	8	9
105	b.b15x2	6.96528	4	4	6
106	b.b15x3	4.62558	4	8	9
107	b.l15x1	5.15728	4	1	7
108	b.l15x2	5.98376	5	8	9
109	b.b16x4	9.02184	5	8	6
110	b.b16x5	5.05614	4	0	5
111	b.b16x6	9.43594	6	8	8
112	b.b16x7	6.63358	4	23	9
113	b.b17x5	7.07117	4	4	7
114	b.b17x7	8.64292	4	4	8
115	b.l17x3	9.47261	6	4	9
116	b.l17x6	8.32675	4	1	9
117	b.b18x3	5.00886	4	4	8
118	b.l18x1	6.46822	6	13	6
119	b.l18x2	5.5775	4	13	7
120	b.b19x2	8.43111	5	4	6
121	b.b19x4	6.10011	4	4	8
122	b.l19x1	6.31697	4	1	9
123	b.l19x2	6.55218	5	4	9
124	b.b20x2	6.36914	4	4	6
125	b.b20x4	10.8399	5	4	8
126	b.b20x6	7.84096	5	4	6
127	b.b20x7	5.27392	4	0	9
128	b.l20x2	7.36547	4	0	9
129	b.b21x1	9.87781	4	4	7
130	b.b21x3	6.83814	4	4	6
131	b.b21x7	6.5463	6	0	5
132	b.b22x5	5.86009	5	13	7
133	b.l22x5	6.89765	6	12	9
134	b.b23x2	4.60764	5	13	6
135	b.b23x6	7.18209	6	16	7
136	b.l23x1	6.30222	4	1	6
137	b.b24x4	7.00162	5	16	6
138	b.b24x6	7.13914	4	16	8
139	b.l24x2	5.69369	4	12	6
140	b.l24x3	5.909	4	0	5
141	b.b25x3	6.23086	4	16	5
142	b.b25x6	2.99278	4	16	3
143	b.l25x3	8.47522	5	10	9
144	b.l25x6	11.2376	5	1	8
145	b.l27x1	9.26247	8	1	9
146	b.l27x2	7.95397	4	10	9
147	b.b28x2	5.40678	4	10	4
148	b.b28x3	4.04053	4	0	7
149	b.b28x4	7.81889	4	10	6
150	b.b28x6	7.86206	6	10	9
151	g.h1x5	2.17484	5	0	6
152	g.h1x11	3.02694	4	0	9
153	g.l1x4	5.31749	5	0	8
154	g.h2x11	11.2193	4	13	6
155	g.ctx3	6.19898	5	12	9
156	g.ctx6	3.49249	5	12	6
157	g.ctx15	7.58267	4	14	9
158	g.ctx16	5.11212	8	14	8
159	1x46	3.27089	6	0	8
160	1x50	6.15564	5	0	9
161	1x60	3.58338	5	15	8
162	I1x48	4.21725	4	10	8
163	I1x50	5.33	5	15	9
164	2x38	2.81328	4	0	7
165	2x39	4.04608	4	6	8
166	2x42	4.94571	5	0	8
167	2x46	5.07742	5	2	9
168	2x50	7.49676	5	2	9
169	2x60	5.29456	4	2	8
170	2x64	4.37806	4	2	7
171	E1x50	6.14113	6	18	9
172	E1x52	5.59883	4	18	7
173	3x28	4.88033	4	0	7
174	3x43	5.14375	4	2	8
175	3x50	6.40665	5	2	9
176	3x51	6.99942	4	0	8
177	I2x51	4.29214	4	6	6
178	I2x53	5.89117	7	6	8
179	4x61	4.333	4	17	8
180	E2	7.32188	11	17	5
181	5x39	6.53227	5	17	8
182	5x47	9.11887	6	2	9
183	5x50	3.52372	4	0	9
184	5x58	6.64527	5	0	9
185	6x44	5.04409	6	2	9
186	6x48	7.15414	7	2	9
187	6x49	3.44728	4	0	7
188	6x51	8.09471	5	2	8
189	6x52	10.2692	5	2	8
190	6x55	6.80767	4	2	8
191	E3	4.71133	4	0	4
192	7x39	6.49397	4	2	8
193	7x42	6.16725	8	2	8
194	7x49	8.00856	4	2	9
195	7x53	4.72178	7	2	9
196	8x50	6.79041	6	15	9
197	8x54	4.21414	4	15	9
198	Lig	8.35254	11	2	0
199	G.hgh4.20	2.98311	4	3	0
200	G.HN.29	0.673556	4	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b3x2	b.b4x6	11.5987	5.32867	No	Yes	7	5	9
2	b.b2x3	b.b3x2	11.7316	3.79733	No	No	7	6	5
3	b.b26x2	b.b2x3	42.4396	4.734	No	No	0	7	6
4	b.b26x1	b.b26x2	42.6437	3.956	No	No	0	9	7
5	b.b26x1	b.l27x1	42.8481	4.81956	No	Yes	0	9	9
6	G.H3.17	b.l27x1	42.3985	4.37422	Yes	Yes	1	5	9
7	G.H3.15	G.H3.17	72.0179	5.24822	No	Yes	0	8	5
8	G.H3.15	G.H3.18	72.1946	8.53844	No	Yes	0	8	9
9	G.H3.18	G.S4.02	72.7451	5.63911	Yes	Yes	3	9	8
10	G.S4.02	G.S5.02	77.6322	4.15856	Yes	No	3	8	6
11	G.H3.09	G.S5.02	77.6223	5.06722	Yes	No	3	9	6
12	G.H3.09	G.S5.04	15.8234	5.25289	Yes	Yes	3	9	9
13	G.S5.04	G.S5.06	33.8166	3.337	Yes	No	0	9	8
14	G.S5.06	G.s4h3.01	34.1224	5.80956	No	Yes	0	8	7
15	G.HG.04	G.s4h3.01	34.9321	7.15544	No	Yes	0	9	7
16	G.HG.04	G.s4h3.04	35.0262	3.47744	No	Yes	0	9	8
17	G.HG.07	G.s4h3.04	99.9838	5.17556	No	Yes	20	9	8
18	G.HG.07	G.s4h3.02	100	3.417	No	No	0	9	9
19	G.HG.03	G.s4h3.02	99.9808	4.57	Yes	No	0	6	9
20	G.HG.03	G.s5hg.01	99.9036	4.44933	Yes	No	0	6	9
21	G.S5.07	G.s5hg.01	99.6223	3.40622	Yes	No	0	9	9
22	G.H1.04	G.S5.07	49.1694	4.84356	No	Yes	5	7	9
23	G.H1.04	G.S5.05	49.1811	4.43744	No	Yes	5	7	9
24	G.S4.03	G.S5.05	11.2421	3.06811	Yes	Yes	5	7	9
25	G.S1.04	G.S4.03	11.1788	4.70989	No	Yes	0	7	7
26	G.S1.04	G.S3.03	11.1552	4.65544	No	Yes	0	7	7
27	G.H3.09	G.H4.15	31.9438	6.70322	Yes	Yes	3	9	8
28	G.H3.06	G.H4.15	33.0957	9.977	Yes	Yes	3	6	8
29	G.H3.06	G.hgh4.02	64.6074	3.644	Yes	Yes	3	6	7
30	G.HG.15	G.hgh4.02	32.6661	3.52778	No	Yes	0	7	7
31	G.HG.15	G.s4h3.04	32.9413	5.66833	No	Yes	0	7	8
32	G.H3.09	G.h4s6.01	31.947	5.60956	Yes	No	0	9	4
33	G.H3.06	G.h4s6.01	32.5827	3.61767	Yes	No	0	6	4
34	G.hgh4.01	G.hgh4.02	32.206	6.85011	No	Yes	0	6	7
35	G.hgh4.01	G.s4h3.04	32.1292	3.77067	No	Yes	0	6	8
36	G.S5.07	G.s6h5.01	49.4005	5.50867	Yes	Yes	5	9	9
37	G.S5.05	G.s6h5.01	49.1493	6.01033	Yes	Yes	5	9	9
38	G.H2.07	b.l9x6	19.4068	4.72722	Yes	Yes	1	9	8
39	G.H2.06	b.l9x6	18.2181	3.23611	Yes	Yes	1	9	8
40	G.H2.04	G.H2.07	20.2439	7.04422	No	Yes	0	9	9
41	G.H2.04	G.H3.08	20.2881	6.05589	No	No	0	9	9
42	G.H2.06	b.l19x1	17.9726	4.85544	Yes	Yes	1	9	9
43	G.S5.03	G.S5.05	43.3062	3.62978	Yes	Yes	5	8	9
44	G.H3.08	G.S4.04	20.3151	5.47378	No	Yes	0	9	9
45	G.H5.10	G.S5.03	43.2132	6.46422	No	Yes	0	6	8
46	G.H5.10	G.S6.02	86.1126	9.81633	No	Yes	0	6	7
47	G.H5.17	G.S6.02	83.831	7.91211	Yes	Yes	11	5	7
48	G.S5.05	G.S6.04	43.6631	6.26178	Yes	No	0	9	9
49	G.H5.10	G.S6.04	43.1226	6.35756	No	No	0	6	9
50	G.H5.17	G.H5.26	80.9701	4.228	Yes	Yes	0	5	5
51	G.H5.20	G.H5.26	80.0777	7.04189	Yes	Yes	0	9	5
52	G.H5.20	G.H5.25	77.1018	4.08956	Yes	Yes	0	9	7
53	3x50	G.H5.25	75.5579	3.30522	Yes	Yes	0	9	7
54	b.l17x5	b.l19x1	17.9869	2.68022	No	Yes	0	6	9
55	b.l17x5	b.l19x2	17.9358	4.66011	No	Yes	0	6	9
56	b.b20x4	b.b20x6	10.44	4.087	Yes	Yes	4	8	6
57	b.b17x7	b.b20x6	15.1486	11.5278	Yes	Yes	4	8	6
58	b.b17x7	b.b21x1	14.4709	3.74267	Yes	Yes	4	8	7
59	b.1x15	g.h1x11	12.0838	1.18922	Yes	Yes	0	7	9
60	b.l17x3	b.l19x2	12.1015	5.56	Yes	Yes	4	9	9
61	b.l2x5	b.l4x2	23.9428	25.8269	No	No	0	5	4
62	b.l4x2	g.ctx16	23.5619	6.55622	No	Yes	14	4	8
63	b.b2x5	b.l4x1	26.3288	5.13244	Yes	No	0	7	5
64	b.l4x1	g.ctx16	26.1267	5.82633	No	Yes	0	5	8
65	b.l2x3	b.l2x5	23.5304	3.38556	No	No	0	8	5
66	b.b3x1	b.l2x3	23.3208	6.12289	No	No	0	5	8
67	b.b3x1	b.b6x5	23.1111	4.662	No	Yes	0	5	6
68	G.H3.17	b.l23x1	22.3679	4.31778	Yes	Yes	1	5	6
69	b.l21x7	b.l23x1	23.1585	3.82033	No	Yes	0	5	6
70	b.l21x7	b.l23x2	22.713	6.172	No	No	0	5	8
71	b.b23x6	b.l23x2	19.8309	3.00278	Yes	No	0	7	8
72	b.b23x6	b.b24x6	17.1674	6.79489	Yes	Yes	16	7	8
73	b.b21x7	b.b24x6	16.1301	11.1124	Yes	Yes	0	5	8
74	2x53	7x42	14.0489	3.17822	No	Yes	0	8	8
75	2x53	7x46	15.9239	3.38733	No	No	0	8	9
76	2x50	7x46	18.5137	10.1436	Yes	No	0	9	9
77	2x46	2x50	23.2078	4.07089	Yes	Yes	2	9	9
78	2x46	7x53	25.2925	3.16644	Yes	Yes	2	9	9
79	3x50	7x53	69.896	5.73644	Yes	Yes	2	9	9
80	3x43	7x53	43.118	6.12122	Yes	Yes	2	8	9
81	6x44	6x48	23.0223	5.83544	Yes	Yes	2	9	9
82	3x43	6x44	42.0023	3.62722	Yes	Yes	2	8	9
83	6x52	Lig	17.9562	7.93622	Yes	Yes	2	8	0
84	6x48	6x52	13.442	6.20289	Yes	Yes	2	9	8
85	5x47	6x52	13.4594	22.3854	Yes	Yes	2	9	8
86	5x47	6x44	17.3868	5.16911	Yes	Yes	2	9	9
87	5x39	5x43	14.0982	11.3743	Yes	No	0	8	9
88	5x43	Lig	14.808	6.76822	No	Yes	0	9	0
89	G.S4.04	G.S5.04	18.7267	3.15322	Yes	Yes	3	9	9
90	b.b2x3	b.b2x5	30.5051	4.27689	No	Yes	7	6	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x53	7x42	3.17822	0	No	Yes	8	8	2	1
2x56	3x32	6.68378	2	No	No	8	8	2	1
2x56	7x42	3.80633	2	No	Yes	8	8	2	1
2x57	7x42	7.75644	0	No	Yes	9	8	2	1
2x60	7x39	6.06811	2	Yes	Yes	8	8	2	2
2x60	7x42	6.94511	2	Yes	Yes	8	8	2	1
3x29	E2x52	3.54778	0	No	No	6	7	2	1
3x32	7x42	8.807	2	No	Yes	8	8	1	1
3x32	Lig	15.008	2	No	Yes	8	0	1	0
3x33	4x57	4.67611	0	No	No	8	9	1	2
3x33	Lig	11.1441	0	No	Yes	8	0	1	0
3x36	6x48	4.26756	0	No	Yes	8	9	1	2
3x36	Lig	6.00422	0	No	Yes	8	0	1	0
3x37	4x56	3.40733	2	No	No	8	8	2	2
3x37	5x461	8.84511	2	No	No	8	8	2	1
4x56	5x461	3.51767	2	No	No	8	8	2	1
E2x52	Lig	4.59844	0	No	Yes	7	0	1	0
5x39	5x43	11.3743	17	Yes	No	8	9	2	1
5x40	6x55	7.28756	0	No	Yes	7	8	2	1
5x43	Lig	6.76822	0	No	Yes	9	0	1	0
5x44	6x52	5.66378	0	No	Yes	8	8	2	1
5x461	Lig	4.26989	2	No	Yes	8	0	1	0
5x47	6x48	3.52022	2	Yes	Yes	9	9	2	2
5x47	6x52	22.3854	2	Yes	Yes	9	8	2	1
6x48	6x52	6.20289	2	Yes	Yes	9	8	2	1
6x51	7x34	3.18789	2	Yes	No	8	5	1	2
6x51	7x38	4.69889	2	Yes	No	8	8	1	1
6x51	Lig	14.2882	2	Yes	Yes	8	0	1	0
6x52	Lig	7.93622	2	Yes	Yes	8	0	1	0
6x55	Lig	6.97822	2	Yes	Yes	8	0	1	0
7x38	7x42	4.63411	2	No	Yes	8	8	1	1
7x38	Lig	5.979	2	No	Yes	8	0	1	0
7x39	7x42	5.30744	2	Yes	Yes	8	8	2	1
7x42	Lig	8.90333	2	Yes	Yes	8	0	1	0
6x51	6x52	9.15789	2	Yes	Yes	8	8	1	1
6x51	6x55	9.14067	2	Yes	Yes	8	8	1	1
5x44	6x55	3.82422	0	No	Yes	8	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
100.00	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
100.00	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
100.00	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
100.00	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
100.00	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
100.00	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
100.00	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
100.00	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
100.00	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
100.00	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
100.00	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
100.00	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
100.00	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
91.67	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
91.67	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
91.67	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
91.67	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
91.67	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
91.67	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
91.67	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
91.67	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
91.67	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
91.67	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
91.67	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
91.67	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
91.67	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
91.67	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
91.67	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
91.67	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
91.67	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
91.67	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
91.67	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
91.67	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
91.67	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
90.91	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
90.91	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
90.91	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
90.91	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
90.91	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
90.91	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
90.91	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
90.91	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
90.91	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
90.91	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
90.91	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
90.91	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
90.91	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
90.91	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
90.91	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
90.91	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
90.91	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
90.91	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
90.91	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
90.91	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
90.91	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
90.91	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
90.91	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
84.62	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
84.62	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
84.62	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
84.62	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
84.62	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
84.62	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
84.62	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
84.62	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
84.62	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
84.62	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
84.62	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
84.62	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
84.62	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
84.62	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
84.62	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
84.62	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
84.62	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
84.62	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
83.33	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
83.33	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
83.33	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
83.33	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
83.33	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
83.33	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
83.33	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
83.33	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
83.33	Single	6PS1	Timolol	6PS1-β₂-Timolol
83.33	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
83.33	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
83.33	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
83.33	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
83.33	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
83.33	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
83.33	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
83.33	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
83.33	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
83.33	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
83.33	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
81.82	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
81.82	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
81.82	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
81.82	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
81.82	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
81.82	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
81.82	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
81.82	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
81.82	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
81.82	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
81.82	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
81.82	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
81.82	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
81.82	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
81.82	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
81.82	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
78.57	Single	3D4S	Timolol	3D4S-β₂-Timolol
78.57	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
78.57	Single	4LDE	BI167107	4LDE-β₂-BI167107
78.57	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
78.57	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
78.57	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
78.57	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
78.57	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
78.57	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
76.92	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
76.92	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
76.92	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
76.92	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
76.92	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-PubChem 129318963
76.92	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
76.92	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
76.92	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
76.92	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
76.92	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
76.92	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
76.92	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
76.92	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
76.92	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
76.92	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
76.92	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
76.92	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
76.92	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
76.92	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
75.00	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
75.00	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
75.00	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
75.00	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
75.00	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
75.00	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
75.00	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
75.00	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
75.00	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
75.00	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
75.00	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
75.00	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
75.00	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
75.00	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
75.00	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
75.00	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
75.00	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
75.00	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
75.00	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
75.00	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
75.00	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
73.33	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
73.33	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
73.33	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
73.33	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
73.33	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
73.33	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
73.33	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
72.73	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
72.73	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
72.73	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
72.73	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
72.73	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
72.73	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
72.73	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
72.73	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
71.43	Single	2YDV	NECA	2YDV-A_2A-NECA
71.43	Single	3P0G	BI167107	3P0G-β₂-BI167107
71.43	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
71.43	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
71.43	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
71.43	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
71.43	Single	5G53	NECA	5G53-A_2A-NECA-Gs
71.43	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
71.43	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
71.43	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
71.43	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
71.43	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
71.43	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
71.43	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
71.43	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
71.43	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
69.23	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
69.23	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
69.23	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
69.23	Single	4QKX	35V	4QKX-β₂-35V
69.23	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
69.23	Single	7BU7	BI167107	7BU7-β₁-BI167107
69.23	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
69.23	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
69.23	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
69.23	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
69.23	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
69.23	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
69.23	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
69.23	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
69.23	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
69.23	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
69.23	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
69.23	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
69.23	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
69.23	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
69.23	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
69.23	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
69.23	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
69.23	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
69.23	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
69.23	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
69.23	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
69.23	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
69.23	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
69.23	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
69.23	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
69.23	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
69.23	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
69.23	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
68.75	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
66.67	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
66.67	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
66.67	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
66.67	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
66.67	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
66.67	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
66.67	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
66.67	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
66.67	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
66.67	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
66.67	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
66.67	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
66.67	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
66.67	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
66.67	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
66.67	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
66.67	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
66.67	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
66.67	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
66.67	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
66.67	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
66.67	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
66.67	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
66.67	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
66.67	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
66.67	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
66.67	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
66.67	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
66.67	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
66.67	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
66.67	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
66.67	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
64.71	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
64.71	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
64.71	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
64.71	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
64.29	Single	5C1M	BU72	5C1M-μ-BU72
64.29	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
64.29	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
64.29	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
64.29	Single	6PS6	Timolol	6PS6-β₂-Timolol
64.29	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
64.29	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
64.29	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
64.29	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
64.29	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
63.64	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
63.64	Single	8GH1	Constrained Epinephrine	8GH1-β₂-Constrained Epinephrine
63.64	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
62.50	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
62.50	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
62.50	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
62.50	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
62.50	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
61.54	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
61.54	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
61.54	Single	6TPG	EMPA	6TPG-OX₂-EMPA
61.54	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
61.54	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
61.54	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
61.54	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
61.54	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
61.54	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
61.54	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
61.54	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
61.54	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
61.54	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
61.54	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
61.54	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
61.54	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8YH2	Adenosine	8YH2-A3A-Adenosine-Gi1/β1/γ2
61.54	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
61.54	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go1/β1/γ2
61.54	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
61.54	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
60.00	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
60.00	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
60.00	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
60.00	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
60.00	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
60.00	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
60.00	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
60.00	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
60.00	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
60.00	Single	8E0G	BU72	8E0G-μ-BU72
60.00	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
60.00	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go1/β1/γ2
60.00	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
60.00	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
60.00	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
60.00	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
58.82	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
58.82	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
58.82	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
58.33	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
58.33	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
58.33	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
58.33	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
58.33	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
58.33	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
58.33	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
58.33	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
58.33	Single	8UO4	Constrained Epinephrine	8UO4-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
58.33	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
58.33	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
58.33	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go1/β1/γ2
58.33	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
58.33	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
58.33	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
58.33	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
57.14	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
57.14	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
57.14	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
57.14	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
57.14	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
57.14	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
57.14	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
57.14	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
57.14	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
57.14	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
57.14	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
57.14	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
57.14	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
57.14	Single	8JXR	LSD	8JXR-D₁-LSD
57.14	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
57.14	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
57.14	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
57.14	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
57.14	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
57.14	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
57.14	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
57.14	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
57.14	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
57.14	Consensus	histamine_off	Orthosteric Ligand	h1_off
56.25	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
56.25	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
56.25	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
56.25	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
56.25	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
56.25	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
56.25	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
56.25	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
56.25	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
56.25	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
56.25	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
56.25	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
56.25	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
56.25	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
56.25	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
56.25	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
55.56	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
55.56	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
55.56	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
55.56	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
55.56	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
54.55	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
54.55	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
54.55	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
54.55	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
54.55	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
54.55	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
53.85	Single	6AKX	A4R	6AKX-CCR5-A4R
53.85	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
53.85	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
53.85	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
53.85	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.85	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
53.85	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
53.85	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
53.85	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
53.85	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
53.85	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
53.85	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
53.85	Consensus	5ht2_on_gp	Orthosteric Ligand	5ht2b_on_gp
53.85	Consensus	5ht2b_on_gp	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.85	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
53.85	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
53.33	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
53.33	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
53.33	Single	5WQC	EMPA	5WQC-OX₂-EMPA
53.33	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
53.33	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
53.33	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/β1/γ2
53.33	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
53.33	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.33	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
53.33	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
53.33	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.33	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
53.33	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go1/β1/γ2
53.33	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
53.33	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
53.33	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.33	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
52.94	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
52.94	Single	5X93	K-8794	5X93-ET_B-K-8794
52.94	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
52.94	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
52.94	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
52.94	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
52.94	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
52.94	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
52.94	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
52.94	Consensus	endothelin_off	Orthosteric Ligand	etb_off
52.94	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
52.63	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
50.00	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
50.00	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
50.00	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
50.00	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
50.00	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
50.00	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
50.00	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
50.00	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
50.00	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
50.00	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
50.00	Single	6FUF	All-trans-Retinal	6FUF-Rhodopsin-All-trans-Retinal-Go
50.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
50.00	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
50.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
50.00	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
50.00	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
50.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
50.00	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
50.00	Single	6VI4	JDTic	6VI4-κ-JDTic
50.00	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
50.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
50.00	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
50.00	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
50.00	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
50.00	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
50.00	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
50.00	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
50.00	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
50.00	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
50.00	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
50.00	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
50.00	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
50.00	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
50.00	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
50.00	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
50.00	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
50.00	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
50.00	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
50.00	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
50.00	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
50.00	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
50.00	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
50.00	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
50.00	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
50.00	Consensus	5ht2_on	Orthosteric Ligand	5ht2b_on
50.00	Consensus	5ht2b_on	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Consensus	a2_on	Orthosteric Ligand	a2b_on
50.00	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
50.00	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
50.00	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
50.00	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
50.00	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A3A-Namodenoson-Gi1/β1/γ2 8X16-A3A-Piclidenoson-Gi1/β1/γ2
50.00	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
50.00	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
50.00	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
50.00	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
50.00	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
50.00	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
50.00	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
47.37	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
47.37	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
47.06	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
47.06	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
47.06	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
47.06	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
46.67	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
46.67	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
46.67	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
46.67	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
46.67	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
46.67	Single	5DHG	C-35	5DHG-NOP-C-35
46.67	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
46.67	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
46.67	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
46.67	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
46.67	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
46.67	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
46.67	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
46.67	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
46.67	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
46.67	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
46.67	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
46.67	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
46.67	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
46.67	Single	8T1W	CVN424	8T1W-GPR6-CVN424
46.67	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
46.67	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/β1/γ2
46.67	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
46.67	Consensus	a3_on	Orthosteric Ligand	a3a_on
46.67	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
46.67	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
46.67	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
46.15	Single	6HLL	CP99994	6HLL-NK₁-CP99994
46.15	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
46.15	Single	8YH3	N-methyladenosine	8YH3-A3A-N-methyladenosine-Gi1/β1/γ2
46.15	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
46.15	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
45.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
45.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
44.44	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
44.44	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
44.44	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
44.44	Single	7EZC	UKA	7EZC-A_2A-UKA
44.44	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/β1/γ2
44.44	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
44.44	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
44.44	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
44.44	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
44.44	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
43.75	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
43.75	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
43.75	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
43.75	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
43.75	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
43.75	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
43.75	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
43.75	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
43.75	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
43.75	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
43.75	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
43.75	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
43.75	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
43.75	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
43.75	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
43.75	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
43.75	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
43.75	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go1/β1/γ2
43.75	Single	8YH0	NECA	8YH0-A3A-NECA-Gi1/β1/γ2
43.75	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
43.75	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
43.75	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
43.75	Consensus	a3a_on	Orthosteric Ligand	8X17-A3A-Namodenoson-Gi1/β1/γ2 8X16-A3A-Piclidenoson-Gi1/β1/γ2
43.75	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A3A-Namodenoson-Gi1/β1/γ2 8X16-A3A-Piclidenoson-Gi1/β1/γ2
42.86	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
42.86	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
42.86	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
42.86	Single	5WS3	EMPA	5WS3-OX₂-EMPA
42.86	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
42.86	Single	6B73	MP1104	6B73-κ-MP1104
42.86	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
42.86	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
42.86	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
42.86	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
42.86	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
42.86	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
42.86	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
42.86	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
42.86	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
42.86	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ
42.86	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
42.86	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
42.86	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
42.86	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
42.86	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
42.86	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
42.86	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
42.86	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
42.11	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
42.11	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
42.11	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
42.11	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
42.11	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
42.11	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
41.67	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
41.67	Single	7MTB	All-trans-Retinal	7MTB-Rhodopsin-All-trans-Retinal-GRK1
41.67	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
41.67	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
41.67	Consensus	sensory_on	Orthosteric Ligand	opsins_on
41.18	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
41.18	Single	4DJH	JDTic	4DJH-κ-JDTic
41.18	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
41.18	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
41.18	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
41.18	Single	6E59	L-760735	6E59-NK₁-L-760735
41.18	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
41.18	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
41.18	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
41.18	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
41.18	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
41.18	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
41.18	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
41.18	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
41.18	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
41.18	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
41.18	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
41.18	Single	8YH6	Namodenoson	8YH6-A3A-Namodenoson-Gi1/β1/γ2
41.18	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
41.18	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
41.18	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
41.18	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
41.18	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
40.91	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
40.91	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
40.91	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
40.00	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
40.00	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
40.00	Single	6IQL	L745870	6IQL-D₄-L745870
40.00	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
40.00	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
40.00	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
40.00	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
40.00	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
40.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
40.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
40.00	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
40.00	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
40.00	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
40.00	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
40.00	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
40.00	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
40.00	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
40.00	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
40.00	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
39.13	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
39.13	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
38.89	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
38.89	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
38.89	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
38.89	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
38.89	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
38.89	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
38.89	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
38.89	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
38.89	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
38.89	Single	8JWY	2-118	8JWY-A_2A-2-118
38.89	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
38.89	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
38.89	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
38.89	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
38.89	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
38.89	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
38.89	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
38.89	Consensus	orexin_on	Orthosteric Ligand	ox2_on
38.89	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
38.89	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
38.46	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
38.46	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
38.46	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
38.46	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
38.46	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
38.46	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
38.46	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
38.46	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
38.46	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
38.10	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
37.50	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
37.50	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
37.50	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
37.50	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
37.50	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
37.50	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
37.50	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
37.50	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
37.50	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
37.50	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
37.50	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
37.50	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
37.50	Single	8YH5	Riboprine	8YH5-A3A-Riboprine-Gi1/β1/γ2
37.50	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
37.50	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
37.50	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
37.50	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
36.84	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
36.84	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
36.84	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
36.84	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
36.84	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
36.84	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
36.84	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
36.84	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
36.84	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
36.84	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
36.84	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
36.84	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
36.84	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
36.84	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
36.36	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
36.36	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
36.36	Single	8GEJ	Constrained Epinephrine	8GEJ-β₂-Constrained Epinephrine-Gs/β1/γ2
36.36	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
36.36	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
36.36	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
36.36	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
36.36	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
36.36	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
36.00	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
36.00	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
35.71	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
35.71	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
35.71	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
35.71	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
35.71	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
35.71	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
35.71	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
35.71	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
35.71	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
35.71	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
35.71	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
35.71	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
35.71	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
35.71	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
35.71	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
35.71	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
35.71	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go1/β1/γ2
35.71	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
35.71	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
35.71	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
35.71	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
35.29	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
35.29	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
35.29	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
35.29	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
35.29	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
35.29	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
35.29	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
35.29	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
35.29	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
35.29	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
35.29	Single	7W41	PD176252	7W41-BB₂-PD176252
35.29	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
35.29	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
35.29	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
35.29	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
35.29	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
35.29	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
35.29	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
35.29	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
35.29	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
35.29	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
35.29	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
35.29	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
35.29	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
35.29	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
35.29	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
35.29	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
35.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
35.00	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
35.00	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
35.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
35.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
35.00	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
35.00	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
35.00	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
35.00	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
35.00	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
35.00	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
34.78	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
34.78	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
34.78	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
34.78	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
34.78	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
34.78	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
34.78	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
34.78	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
34.78	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
34.78	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
34.78	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
33.33	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
33.33	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
33.33	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
33.33	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
33.33	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
33.33	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
33.33	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
33.33	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
33.33	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
33.33	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
33.33	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
33.33	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
33.33	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
33.33	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
33.33	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
33.33	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
33.33	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
33.33	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
33.33	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
33.33	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
33.33	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
33.33	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
33.33	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
33.33	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
33.33	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
33.33	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
33.33	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
33.33	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
33.33	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
33.33	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
33.33	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
33.33	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
33.33	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
33.33	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
33.33	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
33.33	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
33.33	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
33.33	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
33.33	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
33.33	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
33.33	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
33.33	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
33.33	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/β1/γ2
33.33	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
33.33	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
33.33	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
33.33	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
33.33	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
33.33	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
33.33	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
33.33	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
33.33	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
33.33	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
33.33	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
33.33	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
33.33	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
33.33	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
33.33	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
33.33	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
33.33	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
33.33	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
33.33	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
33.33	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
33.33	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
33.33	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
33.33	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
32.00	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
32.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
32.00	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
32.00	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
31.82	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
31.82	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
31.82	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
31.82	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
31.82	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
31.82	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
31.82	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
31.82	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
31.82	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
31.82	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
31.58	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
31.58	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
31.58	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
31.58	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
31.58	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
31.58	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
31.58	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
31.58	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
31.58	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
31.58	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
31.58	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
31.58	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
31.58	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
31.58	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
31.58	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
31.58	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
31.58	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
31.58	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
31.58	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
31.58	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
31.58	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
31.58	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
31.58	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
31.58	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
31.25	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
31.25	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
31.25	Single	3REY	XAC	3REY-A_2A-XAC
31.25	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
31.25	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
31.25	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
31.25	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
31.25	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
31.25	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
31.25	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
31.25	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
31.25	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
31.25	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
31.25	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
31.25	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
31.25	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
31.25	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
31.25	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
31.25	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
31.25	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
31.25	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
31.25	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
31.25	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
31.25	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
31.25	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
31.25	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
31.25	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
31.25	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
31.25	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
31.25	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
31.25	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
31.25	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
31.25	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
31.25	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
31.25	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
31.25	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
31.25	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
31.25	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
31.25	Consensus	a2_off	Orthosteric Ligand	a2a_off
31.25	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
31.25	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
31.25	Consensus	hca_on	Orthosteric Ligand	hca2_on
31.25	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
31.25	Consensus	sensory_off	Orthosteric Ligand	opsins_off
30.77	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
30.77	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
30.77	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
30.77	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
30.77	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
30.77	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
30.77	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
30.77	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
30.43	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
30.43	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
30.43	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
30.43	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
30.43	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
30.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
30.00	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
30.00	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
30.00	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
30.00	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
30.00	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
30.00	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
30.00	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
30.00	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
30.00	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
30.00	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
30.00	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
30.00	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
30.00	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
30.00	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
30.00	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
29.63	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
29.63	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
29.63	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
29.63	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
29.63	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
29.63	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
29.41	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
29.41	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
29.41	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
29.41	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
29.41	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
29.41	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
29.41	Single	5UEN	DU172	5UEN-A₁-DU172
29.41	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
29.41	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
29.41	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
29.41	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
29.41	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
29.41	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
29.41	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
29.41	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
29.41	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
29.41	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
29.41	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
29.41	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
29.41	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
29.41	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
29.41	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
29.41	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
29.41	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
29.41	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
29.41	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
29.41	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
29.41	Consensus	blt_on	Orthosteric Ligand	blt1_on
29.41	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
29.41	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
29.41	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
29.41	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
29.41	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
29.41	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
29.41	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
29.41	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
29.41	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
29.41	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
29.17	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
29.17	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
29.17	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
29.17	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
29.17	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
29.17	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
29.17	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
29.17	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
28.57	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
28.57	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
28.57	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
28.57	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
28.57	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
28.57	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
28.57	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
28.57	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
28.57	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
28.57	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
28.57	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
28.57	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
28.57	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
28.57	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
28.57	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
28.57	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
28.57	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
28.57	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
28.57	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
28.57	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
28.57	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
28.57	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
28.57	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
28.57	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
28.57	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
28.57	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
28.57	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
28.57	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
28.00	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
28.00	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
28.00	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
28.00	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
27.78	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
27.78	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
27.78	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
27.78	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
27.78	Single	5N2S	PSB36	5N2S-A₁-PSB36
27.78	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
27.78	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
27.78	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
27.78	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
27.78	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
27.78	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
27.78	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
27.78	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
27.78	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
27.78	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
27.78	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
27.78	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
27.78	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
27.78	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
27.78	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
27.78	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
27.78	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
27.78	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
27.78	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
27.78	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
27.78	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
27.78	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
27.78	Consensus	dp_off	Orthosteric Ligand	dp2_off
27.78	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
27.78	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
27.27	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
27.27	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
27.27	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
27.27	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
27.27	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
27.27	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
27.27	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
27.27	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
27.27	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
26.92	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
26.92	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
26.92	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
26.92	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
26.92	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
26.67	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
26.67	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
26.67	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
26.67	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
26.67	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
26.67	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
26.67	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
26.67	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
26.67	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
26.67	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
26.67	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
26.67	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
26.67	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
26.32	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
26.32	Single	5XR8	AM841	5XR8-CB₁-AM841
26.32	Single	5XRA	AM11542	5XRA-CB₁-AM11542
26.32	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
26.32	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
26.32	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
26.32	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
26.32	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
26.32	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
26.32	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
26.32	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
26.32	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
26.32	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
26.32	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
26.32	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
26.32	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
26.32	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
26.32	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
26.32	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
26.32	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
26.32	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
26.09	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
26.09	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
26.09	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
26.09	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
26.09	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
26.09	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
26.09	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
26.09	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
25.93	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.93	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
25.93	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
25.93	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
25.93	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
25.93	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
25.00	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
25.00	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
25.00	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
25.00	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
25.00	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
25.00	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
25.00	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
25.00	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
25.00	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
25.00	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
25.00	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
25.00	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
25.00	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
25.00	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
25.00	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
25.00	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
25.00	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
25.00	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
25.00	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
25.00	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
25.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
25.00	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
25.00	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
25.00	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
25.00	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
25.00	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
25.00	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
25.00	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
25.00	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
25.00	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
25.00	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
25.00	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
25.00	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
25.00	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
25.00	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
25.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
25.00	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
25.00	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
25.00	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
25.00	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
25.00	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
25.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
25.00	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
25.00	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
25.00	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
25.00	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
25.00	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
25.00	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
25.00	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
25.00	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
25.00	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
25.00	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
25.00	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
25.00	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
25.00	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
25.00	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
25.00	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
25.00	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
25.00	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
24.14	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
24.14	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
24.14	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
24.14	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
24.14	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
24.14	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
24.14	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
24.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
24.00	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
24.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
24.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
24.00	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
24.00	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
24.00	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
24.00	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
24.00	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
24.00	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
23.81	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
23.81	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
23.81	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
23.81	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
23.81	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
23.81	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
23.81	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
23.81	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
23.81	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
23.81	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
23.81	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
23.81	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
23.81	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
23.81	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
23.81	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
23.81	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
23.81	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
23.53	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
23.53	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
23.53	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
23.53	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
23.53	Single	6TPK	Retosiban	6TPK-OT-Retosiban
23.53	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
23.53	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
23.53	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
23.53	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
23.53	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
23.53	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
23.53	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
23.53	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
23.53	Single	8K9L	Damgo	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
23.53	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
23.53	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
23.53	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
23.53	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
23.53	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
23.53	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
23.53	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
23.33	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
23.08	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
23.08	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
23.08	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
23.08	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
23.08	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
23.08	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
23.08	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
23.08	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
23.08	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
23.08	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
23.08	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
23.08	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
23.08	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
23.08	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
23.08	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
23.08	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
22.73	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
22.73	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
22.73	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
22.73	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
22.73	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
22.73	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
22.73	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
22.73	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
22.73	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
22.58	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
22.22	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
22.22	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
22.22	Single	6D27	CAY10471	6D27-DP₂-CAY10471
22.22	Single	6GPS	MK0812	6GPS-CCR2-MK0812
22.22	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
22.22	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
22.22	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
22.22	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
22.22	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
22.22	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
22.22	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
22.22	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
22.22	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
22.22	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
22.22	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
22.22	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
22.22	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
22.22	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
22.22	Consensus	cck_off	Orthosteric Ligand	ccka_off
22.22	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
22.22	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
22.22	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
22.22	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
21.88	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
21.74	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
21.74	Single	7QA8	Peptide	7QA8-STE2-Peptide
21.74	Single	7QA8	Peptide	7QA8-STE2-Peptide
21.74	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
21.74	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
21.74	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
21.74	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
21.74	Single	8WKY	PG-934	8WKY-MC₄-PG-934
21.74	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
21.74	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
21.74	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
21.74	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
21.74	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
21.74	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
21.74	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
21.43	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
21.43	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
21.43	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
21.43	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
21.43	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
21.43	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
21.43	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
21.43	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
21.43	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
21.43	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
21.05	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
21.05	Single	6GPX	MK0812	6GPX-CCR2-MK0812
21.05	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
21.05	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
21.05	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
21.05	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
21.05	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
21.05	Single	7C4S	S1P	7C4S-S1P₃-S1P
21.05	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
21.05	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
21.05	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
21.05	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
21.05	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
21.05	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
21.05	Single	8WGB	W9R	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
21.05	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
21.05	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
21.05	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
21.05	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
21.05	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
21.05	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
21.05	Consensus	blt_off	Orthosteric Ligand	blt1_off
21.05	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
21.05	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
21.05	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
21.05	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
21.05	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
21.05	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
21.05	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
20.83	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
20.83	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
20.83	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
20.83	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
20.83	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
20.83	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
20.83	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
20.83	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
20.83	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
20.83	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.83	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.83	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.69	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
20.69	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
20.69	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
20.69	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
20.69	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
20.00	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
20.00	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
20.00	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
20.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
20.00	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
20.00	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
20.00	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
20.00	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
20.00	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
20.00	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
20.00	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
20.00	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
20.00	Single	7P2L	4YI	7P2L-mGlu₅-4YI
20.00	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
20.00	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
20.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
20.00	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
20.00	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
20.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
20.00	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
20.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
20.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
20.00	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
20.00	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
20.00	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
20.00	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
20.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
20.00	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
20.00	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
20.00	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
20.00	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
20.00	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
20.00	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
20.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
20.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
20.00	Single	9GE2	ML184	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
20.00	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
20.00	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
20.00	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
20.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
20.00	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
20.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
20.00	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
20.00	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
20.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
20.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
20.00	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
20.00	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
20.00	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
20.00	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
19.35	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
19.35	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
19.35	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
19.35	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
19.35	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
19.23	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
19.23	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
19.23	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
19.23	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
19.23	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
19.23	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
19.23	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
19.23	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
19.23	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
19.23	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
19.23	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
19.05	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
19.05	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
19.05	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
19.05	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
19.05	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
19.05	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
19.05	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
19.05	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
19.05	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
19.05	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
19.05	Single	8XJN	Cloprosetnol	8XJN-TP-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
18.75	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
18.75	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
18.75	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
18.75	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
18.75	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
18.75	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
18.75	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.75	Single	9B9Y	7DY	9B9Y-CB₁-7DY
18.52	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
18.52	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
18.52	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
18.52	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
18.52	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
18.52	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
18.52	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
18.52	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
18.18	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
18.18	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
18.18	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
18.18	Consensus	tp_on	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
17.86	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
17.86	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
17.86	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
17.65	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
17.65	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
17.65	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
17.65	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
17.65	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
17.65	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
17.65	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
17.65	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
17.65	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
17.65	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
17.39	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
17.39	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
17.39	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
17.39	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
17.39	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
17.39	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
17.39	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
17.39	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
17.39	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
17.24	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
17.24	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
17.24	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
17.24	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
17.14	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
17.14	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.67	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
16.67	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
16.67	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
16.67	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
16.67	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
16.67	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
16.67	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
16.67	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
16.67	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
16.67	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
16.67	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
16.67	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
16.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
16.67	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
16.67	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
16.67	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
16.67	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
16.67	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
16.67	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
16.67	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
16.67	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
16.67	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
16.67	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
16.67	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
16.67	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.67	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
16.67	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
16.67	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
16.67	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070-Cholesterol
16.67	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100-Cholesterol
16.67	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
16.67	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
16.67	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
16.67	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
16.67	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
16.13	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
16.13	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
16.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
16.00	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
16.00	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
16.00	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
16.00	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
16.00	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
16.00	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
16.00	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
15.79	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
15.79	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
15.79	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
15.79	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
15.79	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
15.79	Single	6IIV	Daltroban	6IIV-TP-Daltroban
15.79	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
15.79	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
15.79	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
15.79	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
15.79	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
15.79	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
15.79	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
15.79	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
15.79	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
15.79	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
15.79	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
15.62	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
15.62	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
15.62	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
15.38	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
15.38	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
15.38	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
15.38	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
15.38	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
15.38	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
15.38	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
15.15	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
15.15	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
15.00	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
15.00	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
15.00	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
15.00	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
15.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
15.00	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
15.00	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
15.00	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
15.00	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
15.00	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
15.00	Consensus	ep_off	Orthosteric Ligand	ep4_off
15.00	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
14.81	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
14.81	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.81	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
14.81	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
14.81	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
14.81	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
14.81	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
14.81	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
14.81	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
14.81	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
14.81	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
14.81	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
14.71	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
14.71	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
14.63	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
14.29	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
14.29	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
14.29	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
14.29	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
14.29	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
14.29	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
14.29	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
14.29	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
14.29	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
14.29	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
14.29	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
14.29	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
14.29	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
14.29	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
14.29	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
14.29	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.79	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
13.79	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
13.79	Single	6FJ3	PTH	6FJ3-PTH1-PTH
13.79	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
13.79	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
13.79	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
13.79	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
13.79	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
13.79	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
13.79	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
13.79	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
13.79	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
13.64	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
13.64	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
13.64	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
13.64	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
13.64	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
13.64	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
13.64	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
13.64	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
13.64	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
13.64	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
13.64	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
13.64	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
13.64	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
13.64	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
13.33	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
13.33	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
13.33	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
13.33	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
13.33	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
13.33	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
13.33	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
13.33	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
13.33	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
13.16	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
13.04	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
13.04	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
13.04	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
13.04	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
13.04	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
13.04	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
13.04	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
13.04	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
12.90	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.90	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
12.90	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
12.90	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
12.90	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
12.90	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
12.90	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
12.82	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
12.50	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
12.50	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
12.50	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
12.50	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
12.50	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
12.50	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
12.50	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
12.50	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
12.50	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
12.50	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
12.50	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
12.50	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
12.50	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
12.50	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
12.12	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
12.00	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
12.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
12.00	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
12.00	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
12.00	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
11.76	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
11.76	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
11.76	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
11.76	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
11.76	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
11.76	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
11.76	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.54	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
11.54	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
11.54	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
11.54	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
11.54	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
11.54	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
11.54	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
11.43	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
11.43	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
11.43	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
11.11	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
11.11	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
11.11	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
11.11	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
11.11	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
11.11	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
11.11	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
11.11	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
11.11	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
11.11	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
11.11	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
11.11	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
10.71	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
10.71	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
10.71	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
10.53	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
10.53	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.53	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
10.53	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
10.53	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
10.53	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.34	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
10.34	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
10.34	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
10.34	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
10.34	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
10.34	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
10.34	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
10.00	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
10.00	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.00	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
10.00	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
10.00	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
10.00	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
10.00	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
10.00	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
10.00	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
9.68	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
9.52	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
9.52	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
9.52	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
9.52	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
9.52	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.52	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
9.52	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
9.52	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
9.38	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
9.38	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
9.09	Single	5TZR	MK8666	5TZR-FFA1-MK8666
9.09	Single	5V56	TC114	5V56-SMO-TC114
9.09	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
9.09	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
9.09	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
9.09	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
9.09	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
9.09	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.82	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
8.82	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
8.82	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
8.70	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
8.70	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
8.70	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
8.70	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
8.70	Single	6OS2	TRV026	6OS2-AT₁-TRV026
8.70	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
8.70	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
8.70	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.70	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
8.70	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.70	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.33	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
8.33	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
8.33	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
8.33	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
8.33	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
8.33	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
8.00	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
8.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
8.00	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
8.00	Single	8XQJ	JN241	8XQJ-Apelin-JN241
8.00	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
8.00	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
7.69	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
7.69	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
7.69	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
7.69	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
7.41	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
7.41	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
7.41	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
7.41	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
7.41	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/β1/γ2
7.14	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
7.14	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
6.67	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
6.67	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
6.67	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
6.67	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
6.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
6.45	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
6.25	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
6.25	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
6.25	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
6.25	Single	7Y14	Beta-Alanine	7Y14-MRGPRD-β-Alanine
5.88	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
5.88	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
5.88	Single	7Y12	Beta-Alanine	7Y12-MRGPRD-β-Alanine-Gi1/β1/γ2
5.88	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
5.56	Single	6LI0	C17	6LI0-GPR52-C17
5.56	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
5.56	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
5.56	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.56	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
5.56	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
5.56	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
5.56	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.41	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
5.26	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
5.26	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
5.26	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
5.26	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
5.26	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
5.26	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
5.26	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
5.26	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.00	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
5.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
5.00	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
5.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
5.00	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
5.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
5.00	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8IYX	YL-365	8IYX-GPR34-YL-365
5.00	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.76	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
4.76	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
4.76	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
4.76	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
4.76	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
4.76	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.76	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.55	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
4.55	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.55	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.55	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
4.55	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.55	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
4.35	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
4.35	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
4.35	Single	5V57	TC114	5V57-SMO-TC114
4.35	Single	6OS1	TRV026	6OS1-AT₁-TRV026
4.35	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.35	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
4.35	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
4.35	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.35	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.35	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.35	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
4.35	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
4.35	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
4.35	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
4.17	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
4.17	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
4.17	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
4.17	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.17	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
4.17	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
4.17	Single	8XQJ	JN241	8XQJ-Apelin-JN241
4.17	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.17	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116-Cholesterol
4.17	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
4.17	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
4.17	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
4.17	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
4.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.00	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
4.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
4.00	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
4.00	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
4.00	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
4.00	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.85	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
3.85	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
3.85	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
3.85	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
3.85	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.85	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
3.70	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
3.70	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.70	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
3.57	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

Consensus Members
	Id	Members
	d2_on_gp	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
	d1_on_gp	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
	d3_on_gp	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
	d4_on_gp	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
	d5_on_gp	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2

Net Summary
I_min	2.96989
Number of Linked Nodes	935
Number of Links	1155
Number of Hubs	200
Number of Links mediated by Hubs	740
Number of Communities	23
Number of Nodes involved in Communities	248
Number of Links involved in Communities	372

Path Summary
Number Of Nodes in MetaPath	91
Number Of Links MetaPath	90
Number of Shortest Paths	5427443
Length Of Smallest Path	3
Average Path Length	38.4823
Length of Longest Path	60
Minimum Path Strength	0.108556
Average Path Strength	5.69372
Maximum Path Strength	22.0688
Minimum Path Correlation	0.700111
Average Path Correlation	0.990139
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.78571
Average % Of Corr. Nodes	27.2938
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	60.7335
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following differences:
	Id	1^st Network	2^nd Network
	dopamine_off_on_gp	dopamine_on_gp	dopamine_off

This network is also present in following consensuses:
	Id	Components
	amine_on_gp	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download dopamine_on_gp.zip

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