psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D282	R:R:N2	17.5	No	No	0	2	6
2	R:R:G3	R:R:Y10	4.35	No	No	0	6	7
3	R:R:N15	R:R:T4	7.31	No	No	2	7	6
4	R:R:T4	R:R:V20	12.69	No	Yes	2	6	6
5	H:H:?1	R:R:T4	5.27	Yes	No	2	0	6
6	R:R:G6	R:R:P7	4.06	No	No	0	6	6
7	R:R:F9	R:R:G6	9.03	No	No	0	7	6
8	R:R:F9	R:R:S22	6.61	No	Yes	2	7	5
9	R:R:F9	R:R:P23	15.89	No	Yes	2	7	5
10	R:R:T193	R:R:Y10	8.74	Yes	No	0	5	7
11	R:R:P12	R:R:V11	3.53	Yes	Yes	2	8	8
12	R:R:V11	R:R:V20	4.81	Yes	Yes	2	8	6
13	R:R:P23	R:R:V11	3.53	Yes	Yes	2	5	8
14	R:R:Q28	R:R:V11	4.3	Yes	Yes	2	5	8
15	R:R:L31	R:R:V11	4.47	Yes	Yes	2	4	8
16	R:R:L31	R:R:P12	4.93	Yes	Yes	2	4	8
17	R:R:P12	R:R:Q184	4.74	Yes	Yes	2	8	3
18	R:R:P12	R:R:P285	5.84	Yes	Yes	2	8	3
19	R:R:F13	R:R:Y30	8.25	No	Yes	0	4	4
20	R:R:K16	R:R:S14	10.71	No	No	0	7	4
21	R:R:N15	R:R:V20	10.35	No	Yes	2	7	6
22	H:H:?1	R:R:N15	28.24	Yes	No	2	0	7
23	R:R:T17	R:R:V19	4.76	No	No	0	6	3
24	H:H:?1	R:R:G18	7.65	Yes	No	0	0	3
25	R:R:V19	R:R:Y30	3.79	No	Yes	0	3	4
26	R:R:V20	R:R:Y30	12.62	Yes	Yes	2	6	4
27	H:H:?1	R:R:V20	6.66	Yes	Yes	2	0	6
28	H:H:?2	R:R:R21	5.43	No	No	0	0	4
29	R:R:P23	R:R:S22	5.34	Yes	Yes	2	5	5
30	R:R:F24	R:R:S22	3.96	Yes	Yes	2	5	5
31	R:R:E25	R:R:S22	5.75	No	Yes	0	7	5
32	R:R:P23	R:R:Q28	4.74	Yes	Yes	2	5	5
33	R:R:P180	R:R:P23	5.84	Yes	Yes	2	3	5
34	R:R:P23	R:R:Q184	7.9	Yes	Yes	2	5	3
35	R:R:F103	R:R:F24	5.36	Yes	Yes	2	8	5
36	R:R:F24	R:R:G106	6.02	Yes	No	2	5	8
37	R:R:F24	R:R:P107	11.56	Yes	No	2	5	3
38	R:R:C110	R:R:F24	5.59	No	Yes	2	9	5
39	R:R:F24	R:R:P180	7.22	Yes	Yes	2	5	3
40	R:R:P27	R:R:Y29	8.34	No	Yes	0	8	4
41	R:R:P27	R:R:Y102	5.56	No	No	0	8	4
42	R:R:Q28	R:R:Y30	13.53	Yes	Yes	2	5	4
43	R:R:L31	R:R:Q28	9.32	Yes	Yes	2	4	5
44	R:R:Q184	R:R:Q28	5.12	Yes	Yes	2	3	5
45	R:R:P34	R:R:Y29	6.95	No	Yes	0	3	4
46	R:R:F37	R:R:Y29	5.16	Yes	Yes	0	5	4
47	R:R:G101	R:R:Y29	4.35	No	Yes	0	4	4
48	R:R:L31	R:R:Y30	3.52	Yes	Yes	2	4	4
49	R:R:L31	R:R:Q184	3.99	Yes	Yes	2	4	3
50	R:R:L31	R:R:P285	4.93	Yes	Yes	2	4	3
51	R:R:A32	R:R:Q36	4.55	No	No	0	3	2
52	R:R:A32	R:R:F37	4.16	No	Yes	0	3	5
53	R:R:E33	R:R:W35	6.54	No	No	6	3	3
54	R:R:E33	R:R:Q36	6.37	No	No	6	3	2
55	R:R:Q36	R:R:W35	14.24	No	No	6	2	3
56	R:R:F37	R:R:M183	9.95	Yes	No	0	5	2
57	R:R:C185	R:R:F37	4.19	No	Yes	0	5	5
58	R:R:L40	R:R:T94	4.42	No	No	0	5	7
59	R:R:L40	R:R:S98	7.51	No	No	0	5	5
60	R:R:L47	R:R:Y43	15.24	No	Yes	0	7	4
61	R:R:F293	R:R:Y43	11.35	No	Yes	4	5	4
62	R:R:T297	R:R:Y43	6.24	No	Yes	4	6	4
63	R:R:F91	R:R:M44	3.73	Yes	No	0	7	7
64	R:R:M44	R:R:T94	6.02	No	No	0	7	7
65	R:R:F45	R:R:M49	12.44	No	No	0	3	5
66	R:R:L46	R:R:L50	4.15	No	No	0	5	5
67	R:R:F91	R:R:L47	14.61	Yes	No	0	7	7
68	R:R:I48	R:R:V87	4.61	No	No	0	6	6
69	R:R:F52	R:R:P53	5.78	No	No	0	6	4
70	R:R:F52	R:R:F56	8.57	No	No	0	6	4
71	R:R:F52	R:R:F88	5.36	No	No	0	6	4
72	R:R:I54	R:R:N55	4.25	Yes	Yes	5	8	9
73	R:R:I54	R:R:P303	6.77	Yes	No	5	8	9
74	R:R:I54	R:R:M308	4.37	Yes	No	0	8	6
75	R:R:A80	R:R:N55	4.69	No	Yes	0	9	9
76	R:R:D83	R:R:N55	13.46	Yes	Yes	5	9	9
77	R:R:L84	R:R:N55	4.12	No	Yes	0	7	9
78	R:R:N55	R:R:P303	6.52	Yes	No	5	9	9
79	R:R:L57	R:R:M317	9.9	No	No	0	6	6
80	R:R:L321	R:R:L57	5.54	No	No	0	6	6
81	R:R:I307	R:R:T58	12.16	No	No	0	7	9
82	R:R:Q64	R:R:Y60	11.27	No	No	0	5	3
83	R:R:T320	R:R:V61	6.35	No	No	0	5	7
84	R:R:L68	R:R:T62	7.37	Yes	No	0	7	7
85	R:R:L77	R:R:T62	8.84	No	No	0	5	7
86	R:R:H65	R:R:Q64	3.71	Yes	No	0	5	5
87	R:R:H65	R:R:L68	3.86	Yes	Yes	7	5	7
88	R:R:C316	R:R:H65	17.69	No	Yes	7	5	5
89	R:R:H65	R:R:T319	4.11	Yes	No	0	5	4
90	R:R:H65	R:R:T320	5.48	Yes	No	0	5	5
91	R:R:K66	R:R:R69	7.43	No	No	0	6	6
92	R:R:K67	R:R:Q312	4.07	No	No	0	5	6
93	R:R:F313	R:R:L68	10.96	Yes	Yes	0	8	7
94	R:R:C316	R:R:L68	7.94	No	Yes	7	5	7
95	R:R:P71	R:R:T70	3.5	No	No	0	6	7
96	R:R:N73	R:R:T70	5.85	No	No	0	8	7
97	R:R:F313	R:R:N73	9.67	Yes	No	0	8	8
98	R:R:E150	R:R:Y74	5.61	No	No	0	2	5
99	R:R:A153	R:R:Y74	5.34	No	No	0	7	5
100	R:R:I75	R:R:S127	6.19	No	No	0	7	8
101	R:R:I75	R:R:V130	6.14	No	No	0	7	7
102	R:R:I75	R:R:L131	4.28	No	No	0	7	9
103	R:R:I123	R:R:N78	4.25	Yes	Yes	1	7	9
104	R:R:N78	R:R:S127	5.96	Yes	No	1	9	8
105	R:R:N78	R:R:V157	7.39	Yes	No	1	9	7
106	R:R:N78	R:R:T160	4.39	Yes	Yes	1	9	7
107	R:R:N78	R:R:W161	9.04	Yes	No	1	9	9
108	R:R:D83	R:R:L79	5.43	Yes	No	0	9	9
109	R:R:D83	R:R:P303	8.05	Yes	No	5	9	9
110	R:R:G121	R:R:M86	3.49	No	No	0	7	7
111	R:R:F88	R:R:V87	7.87	No	No	0	4	6
112	R:R:F91	R:R:V87	6.55	Yes	No	0	7	6
113	R:R:F88	R:R:T92	3.89	No	No	0	4	8
114	R:R:F91	R:R:K296	7.44	Yes	No	0	7	7
115	R:R:E113	R:R:T93	4.23	Yes	No	0	5	5
116	R:R:S186	R:R:T94	7.99	No	No	0	5	7
117	R:R:H100	R:R:Y96	13.07	No	No	0	4	4
118	R:R:F105	R:R:Y96	7.22	No	No	0	7	4
119	R:R:C185	R:R:S98	3.44	No	No	0	5	5
120	R:R:H100	R:R:V104	8.3	No	No	0	4	4
121	R:R:V104	R:R:Y102	8.83	No	No	0	4	4
122	R:R:E113	R:R:F103	5.83	Yes	Yes	2	5	8
123	R:R:C187	R:R:F103	9.78	Yes	Yes	2	9	8
124	R:R:F105	R:R:V104	7.87	No	No	0	7	4
125	R:R:G106	R:R:P107	4.06	No	No	2	8	3
126	R:R:G109	R:R:T108	3.64	Yes	No	0	5	1
127	R:R:G109	R:R:L112	5.13	Yes	No	0	5	4
128	R:R:C110	R:R:P180	3.77	No	Yes	2	9	3
129	R:R:C110	R:R:C187	7.28	No	Yes	2	9	9
130	R:R:L172	R:R:N111	4.12	Yes	No	1	5	7
131	R:R:N111	R:R:Y178	4.65	No	Yes	1	7	3
132	R:R:E113	R:R:G114	4.91	Yes	No	0	5	5
133	R:R:C187	R:R:E113	4.56	Yes	Yes	2	9	5
134	R:R:G114	R:R:Y178	5.79	No	Yes	0	5	3
135	R:R:F115	R:R:F116	9.65	No	No	0	6	4
136	R:R:F115	R:R:L172	7.31	No	Yes	1	6	5
137	R:R:F115	R:R:Y178	4.13	No	Yes	1	6	3
138	R:R:T118	R:R:Y178	8.74	No	Yes	0	4	3
139	R:R:I123	R:R:L119	7.14	Yes	No	0	7	5
140	R:R:C167	R:R:E122	10.64	No	No	1	5	6
141	R:R:E122	R:R:H211	6.15	No	Yes	1	6	6
142	R:R:I123	R:R:T160	6.08	Yes	Yes	1	7	7
143	R:R:A164	R:R:I123	4.87	No	Yes	0	8	7
144	R:R:L125	R:R:W126	5.69	No	Yes	0	7	5
145	R:R:L125	R:R:W265	18.22	No	No	0	7	8
146	R:R:V129	R:R:W126	6.13	No	Yes	1	7	5
147	R:R:T160	R:R:W126	3.64	Yes	Yes	1	7	5
148	R:R:M163	R:R:W126	19.78	No	Yes	0	4	5
149	R:R:H211	R:R:W126	8.46	Yes	Yes	1	6	5
150	R:R:P215	R:R:W126	8.11	No	Yes	1	9	5
151	R:R:S127	R:R:T160	6.4	No	Yes	1	8	7
152	R:R:L128	R:R:N302	4.12	No	No	0	8	9
153	R:R:L128	R:R:Y306	11.72	No	No	0	8	9
154	R:R:P215	R:R:V129	3.53	No	No	1	9	7
155	R:R:E134	R:R:V130	4.28	No	No	0	8	7
156	R:R:L131	R:R:R135	17.01	No	Yes	0	9	9
157	R:R:A132	R:R:Y223	8.01	No	Yes	0	9	9
158	R:R:E134	R:R:F148	10.49	No	Yes	0	8	7
159	R:R:R135	R:R:Y223	8.23	Yes	Yes	8	9	9
160	R:R:M257	R:R:R135	3.72	No	Yes	8	8	9
161	L:L:M76	R:R:R135	13.65	No	Yes	0	0	9
162	R:R:C140	R:R:Y136	6.72	No	Yes	0	7	7
163	R:R:P142	R:R:Y136	9.74	No	Yes	0	8	7
164	R:R:F221	R:R:Y136	4.13	No	Yes	9	4	7
165	R:R:C222	R:R:Y136	8.06	No	Yes	0	8	7
166	R:R:Q225	R:R:Y136	7.89	No	Yes	9	4	7
167	R:R:P142	R:R:V137	5.3	No	No	0	8	4
168	R:R:F146	R:R:V137	3.93	No	No	0	5	4
169	R:R:L226	R:R:V139	8.94	No	No	0	8	8
170	R:R:C140	R:R:T229	5.07	No	No	0	7	6
171	R:R:F146	R:R:M143	3.73	No	No	0	5	6
172	R:R:N145	R:R:S144	7.45	No	No	0	5	4
173	R:R:F146	R:R:H152	6.79	No	No	0	5	5
174	R:R:F148	R:R:H152	5.66	Yes	No	0	7	5
175	R:R:V157	R:R:W161	7.36	No	No	1	7	9
176	R:R:F159	R:R:M163	8.71	No	No	0	3	4
177	R:R:C167	R:R:M207	6.48	No	No	1	5	5
178	R:R:C167	R:R:H211	4.42	No	Yes	1	5	6
179	R:R:P170	R:R:P171	5.84	No	No	1	7	5
180	R:R:F203	R:R:P170	4.33	Yes	No	1	6	7
181	R:R:P171	R:R:Y178	9.74	No	Yes	1	5	3
182	R:R:F203	R:R:P171	5.78	Yes	No	1	6	5
183	R:R:L172	R:R:Y178	4.69	Yes	Yes	1	5	3
184	R:R:S202	R:R:W175	7.41	No	No	0	4	5
185	R:R:F203	R:R:W175	24.05	Yes	No	1	6	5
186	R:R:W175	R:R:Y206	9.65	No	Yes	1	5	4
187	R:R:N200	R:R:S176	4.47	Yes	No	0	4	5
188	R:R:F203	R:R:S176	11.89	Yes	No	0	6	5
189	R:R:I179	R:R:R177	10.02	No	Yes	3	1	5
190	R:R:D190	R:R:R177	15.48	Yes	Yes	3	4	5
191	R:R:R177	R:R:T193	3.88	Yes	Yes	3	5	5
192	R:R:H195	R:R:R177	24.83	Yes	Yes	3	4	5
193	R:R:I189	R:R:Y178	3.63	No	Yes	0	4	3
194	R:R:D190	R:R:I179	7	Yes	No	3	4	1
195	R:R:I179	R:R:Y192	6.04	No	Yes	3	1	5
196	R:R:P180	R:R:Q184	6.32	Yes	Yes	2	3	3
197	R:R:C187	R:R:P180	5.65	Yes	Yes	2	9	3
198	R:R:I286	R:R:M183	4.37	No	No	0	1	2
199	R:R:F203	R:R:I189	3.77	Yes	No	0	6	4
200	R:R:D190	R:R:Y192	4.6	Yes	Yes	3	4	5
201	R:R:D190	R:R:T193	7.23	Yes	Yes	3	4	5
202	R:R:D190	R:R:N200	8.08	Yes	Yes	3	4	4
203	R:R:Y191	R:R:Y192	7.94	Yes	Yes	3	6	5
204	R:R:Y191	R:R:Y268	5.96	Yes	Yes	0	6	6
205	R:R:V271	R:R:Y191	3.79	No	Yes	0	5	6
206	R:R:M288	R:R:Y191	3.59	Yes	Yes	3	4	6
207	R:R:M288	R:R:Y192	7.18	Yes	Yes	3	4	5
208	R:R:P194	R:R:Q279	12.63	No	No	0	1	1
209	R:R:E197	R:R:H195	20.92	No	Yes	0	3	4
210	R:R:H195	R:R:T198	9.58	Yes	No	3	4	1
211	R:R:H195	R:R:N200	6.38	Yes	Yes	3	4	4
212	R:R:N200	R:R:T198	5.85	Yes	No	3	4	1
213	R:R:E201	R:R:F276	8.16	No	No	0	3	4
214	R:R:F203	R:R:Y206	4.13	Yes	Yes	1	6	4
215	R:R:F203	R:R:M207	6.22	Yes	No	1	6	5
216	R:R:F276	R:R:I205	6.28	No	No	0	4	5
217	R:R:V210	R:R:Y206	6.31	No	Yes	1	4	4
218	R:R:H211	R:R:Y206	9.8	Yes	Yes	1	6	4
219	R:R:H211	R:R:M207	5.25	Yes	No	1	6	5
220	R:R:F208	R:R:F212	4.29	No	Yes	10	5	8
221	R:R:I213	R:R:V209	7.68	No	No	0	4	5
222	R:R:H211	R:R:V210	11.07	Yes	No	1	6	4
223	R:R:A269	R:R:F212	8.32	No	Yes	0	7	8
224	R:R:F220	R:R:L216	4.87	No	Yes	0	5	7
225	R:R:F261	R:R:L216	3.65	No	Yes	0	9	7
226	R:R:F261	R:R:I219	7.54	No	No	0	9	8
227	R:R:F220	R:R:V258	5.24	No	No	0	5	8
228	R:R:F221	R:R:Q225	12.88	No	No	9	4	4
229	R:R:V254	R:R:Y223	7.57	No	Yes	0	8	9
230	R:R:M257	R:R:Y223	13.17	No	Yes	8	8	9
231	R:R:V227	R:R:V254	4.81	No	No	0	5	8
232	R:R:E232	R:R:F228	7	No	No	0	4	3
233	R:R:V230	R:R:V250	4.81	No	No	0	8	8
234	R:R:E247	R:R:K231	12.15	Yes	No	11	7	5
235	R:R:K231	R:R:T251	9.01	No	No	11	5	6
236	R:R:A234	R:R:Q244	4.55	No	No	0	5	4
237	R:R:E239	R:R:Q237	5.1	No	No	0	2	5
238	R:R:Q237	R:R:S240	5.78	No	No	12	5	4
239	R:R:Q237	R:R:T243	7.09	No	No	12	5	5
240	R:R:S240	R:R:T243	6.4	No	No	12	4	5
241	R:R:E247	R:R:K248	5.4	Yes	No	0	7	4
242	R:R:E247	R:R:T251	5.64	Yes	No	11	7	6
243	R:R:E249	R:R:R252	5.82	No	No	0	7	7
244	L:L:L78	R:R:E249	6.63	No	No	0	0	7
245	R:R:I256	R:R:R252	6.26	No	No	0	5	7
246	R:R:M253	R:R:M309	4.33	No	No	0	8	7
247	R:R:I256	R:R:I305	4.42	No	No	0	5	8
248	R:R:M257	R:R:Y306	13.17	No	No	0	8	9
249	R:R:F261	R:R:W265	4.01	No	No	0	9	8
250	R:R:C264	R:R:W265	11.75	No	No	0	8	8
251	R:R:C264	R:R:S298	3.44	No	No	4	8	9
252	R:R:C264	R:R:Y301	4.03	No	Yes	4	8	5
253	R:R:F294	R:R:P267	5.78	No	No	0	7	9
254	R:R:P291	R:R:Y268	12.52	No	Yes	0	6	6
255	R:R:A292	R:R:Y268	4	No	Yes	0	5	6
256	R:R:F287	R:R:V271	5.24	No	No	0	4	5
257	R:R:P291	R:R:V271	5.3	No	No	0	6	5
258	R:R:H278	R:R:Y274	13.07	No	No	0	3	4
259	R:R:F283	R:R:Y274	4.13	Yes	No	0	4	4
260	R:R:F283	R:R:I275	18.84	Yes	No	0	4	4
261	R:R:H278	R:R:T277	10.95	No	No	0	3	5
262	R:R:F283	R:R:S281	10.57	Yes	No	0	4	4
263	R:R:F283	R:R:F287	8.57	Yes	No	3	4	4
264	R:R:F283	R:R:M288	3.73	Yes	Yes	3	4	4
265	R:R:G284	R:R:P285	4.06	No	Yes	0	4	3
266	R:R:F287	R:R:M288	3.73	No	Yes	3	4	4
267	R:R:F293	R:R:F294	13.93	No	No	0	5	7
268	R:R:F293	R:R:T297	3.89	No	No	4	5	6
269	R:R:T297	R:R:Y301	4.99	No	Yes	4	6	5
270	R:R:S298	R:R:Y301	6.36	No	Yes	4	9	5
271	R:R:N302	R:R:S298	7.45	No	No	4	9	9
272	R:R:N302	R:R:Y301	4.65	No	Yes	4	9	5
273	R:R:I305	R:R:Y306	6.04	No	No	0	8	9
274	R:R:F313	R:R:I307	3.77	Yes	No	0	8	7
275	R:R:F313	R:R:N310	8.46	Yes	No	0	8	8
276	L:L:G77	R:R:N310	6.79	No	No	0	0	8
277	R:R:K311	R:R:R314	3.71	No	No	0	4	8
278	H:H:?4	R:R:C323	8.3	No	No	0	0	9
279	L:L:D72	L:L:V75	11.69	No	No	0	0	0
280	H:H:?1	H:H:?2	37.64	Yes	No	0	0	0
281	H:H:?2	H:H:?3	29.54	No	No	0	0	0
282	H:H:?3	H:H:?5	36.93	No	No	0	0	0
283	R:R:A41	R:R:S98	3.42	No	No	0	5	5
284	R:R:I214	R:R:P215	3.39	No	No	0	5	9
285	R:R:I290	R:R:P291	3.39	No	No	0	5	6
286	R:R:C185	R:R:T97	3.38	No	No	0	5	5
287	R:R:E181	R:R:Y192	3.37	No	Yes	0	4	5
288	R:R:E181	R:R:Y268	3.37	No	Yes	0	4	6
289	R:R:A80	R:R:T58	3.36	No	No	0	9	9
290	R:R:A168	R:R:T118	3.36	No	No	0	7	4
291	R:R:N8	R:R:P107	3.26	No	No	0	4	3
292	R:R:A82	R:R:I123	3.25	No	Yes	0	8	7
293	R:R:F116	R:R:F85	3.22	No	No	0	4	6
294	R:R:V129	R:R:V218	3.21	No	No	0	7	6
295	R:R:A41	R:R:L99	3.15	No	No	0	5	4
296	R:R:A299	R:R:D83	3.09	No	Yes	0	9	9
297	R:R:I133	R:R:V218	3.07	No	No	0	6	6
298	R:R:M317	R:R:V61	3.04	No	No	0	6	7
299	R:R:K231	R:R:V227	3.04	No	No	0	5	5
300	R:R:I286	R:R:T289	3.04	No	No	0	1	4
301	R:R:A117	R:R:E113	3.02	No	Yes	0	5	5
302	R:R:A234	R:R:E247	3.02	No	Yes	0	5	7
303	R:R:L50	R:R:V300	2.98	No	No	0	5	7
304	R:R:L59	R:R:V81	2.98	No	No	0	7	6
305	R:R:N199	R:R:S202	2.98	No	No	0	3	4
306	R:R:I255	R:R:I259	2.94	No	No	0	5	5
307	R:R:I259	R:R:I263	2.94	No	No	0	5	5
308	R:R:A166	R:R:H211	2.93	No	Yes	0	4	6
309	L:L:I73	R:R:K141	2.91	No	No	0	0	6
310	R:R:E247	R:R:V230	2.85	Yes	No	0	7	8
311	R:R:L95	R:R:M44	2.83	No	No	0	6	7
312	R:R:A26	R:R:R21	2.77	No	No	0	2	4
313	R:R:L128	R:R:L79	2.77	No	No	0	8	9
314	R:R:A299	R:R:F91	2.77	No	Yes	0	9	7
315	R:R:A153	R:R:F148	2.77	No	Yes	0	7	7
316	R:R:L76	R:R:N73	2.75	No	No	0	8	8
317	R:R:E150	R:R:I154	2.73	No	No	0	2	3
318	R:R:A272	R:R:Y191	2.67	No	Yes	0	5	6
319	R:R:A295	R:R:Y268	2.67	No	Yes	0	8	6
320	R:R:L68	R:R:Q312	2.66	Yes	No	0	7	6
321	R:R:E150	R:R:N151	2.63	No	No	0	2	4
322	R:R:F85	R:R:V81	2.62	No	No	0	6	6
323	R:R:F148	R:R:V138	2.62	Yes	No	0	7	8
324	R:R:E196	R:R:E197	2.54	No	No	0	1	3
325	R:R:V204	R:R:Y191	2.52	No	Yes	0	4	6
326	R:R:F208	R:R:I213	2.51	No	No	10	5	4
327	R:R:F212	R:R:I213	2.51	Yes	No	10	8	4
328	R:R:F294	R:R:I263	2.51	No	No	0	7	5
329	R:R:F91	R:R:M86	2.49	Yes	No	0	7	7
330	R:R:F212	R:R:L216	2.44	Yes	Yes	0	8	7
331	R:R:L46	R:R:Y43	2.34	No	Yes	0	5	4
332	R:R:M39	R:R:W35	2.33	No	No	0	4	3
333	R:R:E5	R:R:Y10	2.24	No	No	0	6	7
334	R:R:F208	R:R:F273	2.14	No	No	0	5	6
335	R:R:G89	R:R:G90	2.11	No	No	0	4	6
336	R:R:G120	R:R:G121	2.11	No	No	0	8	7
337	R:R:G51	R:R:P53	2.03	No	No	0	8	4
338	R:R:G182	R:R:P285	2.03	No	Yes	0	3	3
339	R:R:A117	R:R:G90	1.95	No	No	0	5	6
340	R:R:A169	R:R:P170	1.87	No	No	0	3	7
341	R:R:G156	R:R:V130	1.84	No	No	0	6	7
342	R:R:G174	R:R:T198	1.82	No	No	0	5	1
343	R:R:A124	R:R:A82	1.79	No	No	0	9	8
344	R:R:G156	R:R:M155	1.75	No	No	0	6	2
345	R:R:P194	R:R:T193	1.75	No	Yes	0	1	5
346	R:R:G324	R:R:K325	1.74	No	No	0	3	3
347	R:R:A234	R:R:T243	1.68	No	No	0	5	5
348	R:R:K141	R:R:P142	1.67	No	No	0	6	8
349	R:R:E181	R:R:G188	1.64	No	No	0	4	5
350	R:R:L266	R:R:P267	1.64	No	No	0	6	9
351	R:R:A260	R:R:I305	1.62	No	No	0	7	8
352	R:R:A42	R:R:M39	1.61	No	No	0	5	4
353	R:R:V139	R:R:V230	1.6	No	No	0	8	8
354	R:R:S240	R:R:T242	1.6	No	No	0	4	4
355	R:R:G149	R:R:H152	1.59	No	No	0	6	5
356	R:R:I54	R:R:V304	1.54	Yes	No	0	8	7
357	R:R:I205	R:R:V209	1.54	No	No	0	5	5
358	R:R:F103	R:R:G109	1.51	Yes	Yes	0	8	5
359	R:R:F105	R:R:G109	1.51	No	Yes	0	7	5
360	R:R:K16	R:R:T17	1.5	No	No	0	7	6
361	R:R:G149	R:R:R147	1.5	No	No	0	6	4
362	R:R:L172	R:R:V173	1.49	Yes	No	0	5	4
363	R:R:L72	R:R:T70	1.47	No	No	0	8	7
364	R:R:I48	R:R:M49	1.46	No	No	0	6	5
365	R:R:I256	R:R:M253	1.46	No	No	0	5	8
366	R:R:Q64	R:R:V63	1.43	No	No	0	5	2
367	R:R:K311	R:R:N315	1.4	No	No	0	4	5
368	R:R:L119	R:R:L165	1.38	No	No	0	5	3
369	R:R:L216	R:R:L262	1.38	Yes	No	0	7	6
370	R:R:L262	R:R:L266	1.38	No	No	0	6	6
371	H:H:?4	R:R:C322	1.38	No	No	0	0	4
372	L:L:D74	L:L:L78	1.36	No	No	0	0	0
373	L:L:D72	L:L:D74	1.33	No	No	0	0	0
374	R:R:R314	R:R:V318	1.31	No	No	0	8	3
375	R:R:R69	R:R:T62	1.29	No	No	0	6	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:V11	4.128	5	2	8
2	R:R:P12	4.76	4	2	8
3	R:R:V20	9.426	5	2	6
4	R:R:S22	5.415	4	2	5
5	R:R:P23	7.20667	6	2	5
6	R:R:F24	6.61833	6	2	5
7	R:R:Q28	7.402	5	2	5
8	R:R:Y29	6.2	4	0	4
9	R:R:Y30	8.342	5	2	4
10	R:R:L31	5.19333	6	2	4
11	R:R:F37	5.865	4	0	5
12	R:R:Y43	8.7925	4	4	4
13	R:R:I54	4.2325	4	5	8
14	R:R:N55	6.608	5	5	9
15	R:R:H65	6.97	5	7	5
16	R:R:L68	6.558	5	7	7
17	R:R:N78	6.206	5	1	9
18	R:R:D83	7.5075	4	5	9
19	R:R:F91	6.265	6	0	7
20	R:R:F103	5.62	4	2	8
21	R:R:G109	2.9475	4	0	5
22	R:R:E113	4.51	5	2	5
23	R:R:I123	5.118	5	1	7
24	R:R:W126	8.635	6	1	5
25	R:R:R135	10.6525	4	8	9
26	R:R:Y136	7.308	5	9	7
27	R:R:F148	5.385	4	0	7
28	R:R:T160	5.1275	4	1	7
29	R:R:L172	4.4025	4	1	5
30	R:R:R177	13.5525	4	3	5
31	R:R:Y178	5.91	7	1	3
32	R:R:P180	5.76	5	2	3
33	R:R:Q184	5.614	5	2	3
34	R:R:C187	6.8175	4	2	9
35	R:R:D190	8.478	5	3	4
36	R:R:Y191	4.41167	6	3	6
37	R:R:Y192	5.826	5	3	5
38	R:R:T193	5.4	4	3	5
39	R:R:H195	15.4275	4	3	4
40	R:R:N200	6.195	4	3	4
41	R:R:F203	8.59571	7	1	6
42	R:R:Y206	7.4725	4	1	4
43	R:R:H211	6.86857	7	1	6
44	R:R:F212	4.39	4	10	8
45	R:R:L216	3.085	4	0	7
46	R:R:Y223	9.245	4	8	9
47	R:R:E247	5.812	5	11	7
48	R:R:Y268	5.704	5	0	6
49	R:R:F283	9.168	5	3	4
50	R:R:P285	4.215	4	2	3
51	R:R:M288	4.5575	4	3	4
52	R:R:Y301	5.0075	4	4	5
53	R:R:F313	8.215	4	0	8
54	H:H:?1	17.092	5	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D190	R:R:N200	27.8064	8.08	Yes	Yes	3	4	4
2	R:R:N200	R:R:S176	32.9696	4.47	Yes	No	0	4	5
3	R:R:F203	R:R:S176	33.6892	11.89	Yes	No	0	6	5
4	R:R:F203	R:R:P171	42.7732	5.78	Yes	No	1	6	5
5	R:R:P171	R:R:Y178	42.5176	9.74	No	Yes	1	5	3
6	R:R:G114	R:R:Y178	73.0474	5.79	No	Yes	0	5	3
7	R:R:E113	R:R:G114	71.9756	4.91	Yes	No	0	5	5
8	R:R:C187	R:R:E113	50.7909	4.56	Yes	Yes	2	9	5
9	R:R:C187	R:R:P180	52.7003	5.65	Yes	Yes	2	9	3
10	R:R:P180	R:R:P23	27.046	5.84	Yes	Yes	2	3	5
11	R:R:P23	R:R:V11	15.5543	3.53	Yes	Yes	2	5	8
12	R:R:V11	R:R:V20	14.2366	4.81	Yes	Yes	2	8	6
13	R:R:F203	R:R:I189	42.7754	3.77	Yes	No	0	6	4
14	R:R:I189	R:R:Y178	42.2964	3.63	No	Yes	0	4	3
15	H:H:?1	R:R:V20	10.057	6.66	Yes	Yes	2	0	6
16	R:R:E113	R:R:F103	16.2652	5.83	Yes	Yes	2	5	8
17	R:R:F103	R:R:F24	13.7362	5.36	Yes	Yes	2	8	5
18	R:R:P180	R:R:Q184	28.6805	6.32	Yes	Yes	2	3	3
19	R:R:L31	R:R:Q184	13.0951	3.99	Yes	Yes	2	4	3
20	R:R:Q28	R:R:Y30	16.3286	13.53	Yes	Yes	2	5	4
21	R:R:V19	R:R:Y30	16.1718	3.79	No	Yes	0	3	4
22	R:R:T17	R:R:V19	12.1318	4.76	No	No	0	6	3
23	R:R:F103	R:R:G109	19.7124	1.51	Yes	Yes	0	8	5
24	R:R:F105	R:R:G109	17.4347	1.51	No	Yes	0	7	5
25	R:R:F105	R:R:V104	15.6703	7.87	No	No	0	7	4
26	R:R:V104	R:R:Y102	14.7607	8.83	No	No	0	4	4
27	R:R:P27	R:R:Y102	14.3515	5.56	No	No	0	8	4
28	R:R:P27	R:R:Y29	14.039	8.34	No	Yes	0	8	4
29	R:R:F37	R:R:Y29	13.5397	5.16	Yes	Yes	0	5	4
30	R:R:C185	R:R:F37	12.7665	4.19	No	Yes	0	5	5
31	R:R:F203	R:R:Y206	49.9769	4.13	Yes	Yes	1	6	4
32	R:R:H211	R:R:Y206	50.5289	9.8	Yes	Yes	1	6	4
33	R:R:H211	R:R:W126	100	8.46	Yes	Yes	1	6	5
34	R:R:L125	R:R:W126	65.7481	5.69	No	Yes	0	7	5
35	R:R:L125	R:R:W265	65.3937	18.22	No	No	0	7	8
36	R:R:C264	R:R:W265	59.4207	11.75	No	No	0	8	8
37	R:R:C264	R:R:Y301	34.7072	4.03	No	Yes	4	8	5
38	R:R:T297	R:R:Y301	11.3725	4.99	No	Yes	4	6	5
39	R:R:F91	R:R:M44	13.2669	3.73	Yes	No	0	7	7
40	R:R:M44	R:R:T94	12.8696	6.02	No	No	0	7	7
41	R:R:L40	R:R:T94	12.5818	4.42	No	No	0	5	7
42	R:R:F203	R:R:M207	50.2443	6.22	Yes	No	1	6	5
43	R:R:H211	R:R:M207	49.717	5.25	Yes	No	1	6	5
44	R:R:C185	R:R:S98	12.6269	3.44	No	No	0	5	5
45	R:R:C264	R:R:S298	24.401	3.44	No	No	4	8	9
46	R:R:N302	R:R:S298	23.9758	7.45	No	No	4	9	9
47	R:R:L128	R:R:N302	47.9934	4.12	No	No	0	8	9
48	R:R:L128	R:R:L79	40.197	2.77	No	No	0	8	9
49	R:R:D83	R:R:L79	39.2562	5.43	Yes	No	0	9	9
50	R:R:D83	R:R:N55	37.7721	13.46	Yes	Yes	5	9	9
51	R:R:N302	R:R:Y301	24.9101	4.65	No	Yes	4	9	5
52	R:R:A80	R:R:N55	32.4016	4.69	No	Yes	0	9	9
53	R:R:A80	R:R:T58	31.3137	3.36	No	No	0	9	9
54	R:R:I307	R:R:T58	30.2237	12.16	No	No	0	7	9
55	R:R:F313	R:R:I307	29.1315	3.77	Yes	No	0	8	7
56	R:R:F313	R:R:L68	20.3342	10.96	Yes	Yes	0	8	7
57	R:R:H65	R:R:L68	11.3704	3.86	Yes	Yes	7	5	7
58	R:R:E134	R:R:F148	15.0431	10.49	No	Yes	0	8	7
59	R:R:E134	R:R:V130	15.7025	4.28	No	No	0	8	7
60	R:R:I75	R:R:V130	17.6677	6.14	No	No	0	7	7
61	R:R:I75	R:R:S127	32.4907	6.19	No	No	0	7	8
62	R:R:S127	R:R:T160	31.9162	6.4	No	Yes	1	8	7
63	R:R:T160	R:R:W126	37.5004	3.64	Yes	Yes	1	7	5
64	R:R:I75	R:R:L131	21.7077	4.28	No	No	0	7	9
65	R:R:L128	R:R:Y306	19.5717	11.72	No	No	0	8	9
66	R:R:L131	R:R:R135	21.3018	17.01	No	Yes	0	9	9
67	R:R:M257	R:R:R135	10.5285	3.72	No	Yes	8	8	9
68	R:R:M257	R:R:Y306	13.1681	13.17	No	No	0	8	9
69	R:R:R135	R:R:Y223	10.0377	8.23	Yes	Yes	8	9	9
70	R:R:F148	R:R:H152	10.3674	5.66	Yes	No	0	7	5
71	R:R:V254	R:R:Y223	11.7173	7.57	No	Yes	0	8	9
72	R:R:V227	R:R:V254	11.0439	4.81	No	No	0	5	8
73	R:R:K231	R:R:V227	10.3695	3.04	No	No	0	5	5
74	R:R:D190	R:R:Y192	21.1944	4.6	Yes	Yes	3	4	5
75	R:R:F261	R:R:L216	10.681	3.65	No	Yes	0	9	7
76	R:R:F261	R:R:W265	12.1329	4.01	No	No	0	9	8
77	R:R:I256	R:R:I305	14.3021	4.42	No	No	0	5	8
78	R:R:I305	R:R:Y306	17.4637	6.04	No	No	0	8	9
79	R:R:A299	R:R:D83	10.9527	3.09	No	Yes	0	9	9
80	R:R:A299	R:R:F91	10.8292	2.77	No	Yes	0	9	7
81	R:R:L40	R:R:S98	12.4432	7.51	No	No	0	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L131	R:R:R135	17.01	0	No	Yes	9	9	2	1
R:R:R135	R:R:Y223	8.23	8	Yes	Yes	9	9	1	2
R:R:M257	R:R:R135	3.72	8	No	Yes	8	9	2	1
L:L:M76	R:R:R135	13.65	0	No	Yes	0	9	0	1
R:R:M257	R:R:Y223	13.17	8	No	Yes	8	9	2	2
R:R:E249	R:R:R252	5.82	0	No	No	7	7	1	2
L:L:L78	R:R:E249	6.63	0	No	No	0	7	0	1
R:R:F313	R:R:N310	8.46	0	Yes	No	8	8	2	1
L:L:G77	R:R:N310	6.79	0	No	No	0	8	0	1
L:L:I73	R:R:K141	2.91	0	No	No	0	6	0	1
R:R:K141	R:R:P142	1.67	0	No	No	6	8	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
22.22	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
20.00	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
20.00	Single	6KK7	PF-06372222	6KK7-GLP-1-PF-06372222
18.18	Single	6KJV	PF-06372222	6KJV-GLP-1-PF-06372222
18.18	Single	6KK1	PF-06372222	6KK1-GLP-1-PF-06372222
16.67	Single	5X7D	Cmpd-15	5X7D-β₂-S-Carazolol-Cmpd-15
16.67	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
15.38	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
15.38	Single	8JPC	SBI-553; GDP; Mg	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
15.38	Single	8JPF	SBI-553	8JPF-NTS₁-Neurotensin-SBI-553
13.33	Single	8JPB	SBI-553; GDP; Mg	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
12.50	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
12.50	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
12.50	Single	8ZYU	SBI-553	8ZYU-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
12.50	Single	8ZYY	SBI-553	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
11.76	Single	6LN2	PF-06372222	6LN2-GLP-1-PF-06372222
10.53	Single	8ZYT	SBI-553	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
10.00	Single	8XQP	Aristolochic acid A	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.09	Single	5T1A	PubChem 12093170	5T1A-CCR2-BMS-681-PubChem 12093170
9.09	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
9.09	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
9.09	Single	9CM3	Compound 187	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.33	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
8.33	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
8.33	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/β1/γ2
8.33	Single	8XQN	Aristolochic acid A	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
8.33	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
7.69	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
7.69	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
7.69	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
7.69	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
7.69	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
7.14	Single	6QZH	Cmp2105; Na	6QZH-CCR7-Cmp2105; Na
7.14	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
6.67	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
6.67	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/β1/γ2
6.67	Single	8GW8	PCO371	8GW8-PTH1-PCO371-Gs/β1/γ2
6.25	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/β1/γ2
6.25	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
5.88	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8FN0	SBI-553	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
4.00	Single	3VG9	Antibody	3VG9-A_2A-ZM-241385-Antibody
3.57	Single	3VGA	Antibody	3VGA-A_2A-ZM-241385-Antibody

PDB Summary
PDB	4PXF
Class	A
SubFamily	Sensory
Type	Opsins
SubType	Rhodopsin
Species	Bos Taurus
Ligand	Octyl-Beta-D-Glucopyranoside
Other Ligand(s)	-
Protein Partners	Arrestin1 Finger Loop
PDB Resolution	2.75
Date	2014-09-17
D.O.I.	doi.org/10.1038/ncomms5801

Net Summary
I_min	3.44
Number of Linked Nodes	322
Number of Links	375
Number of Hubs	54
Number of Links mediated by Hubs	200
Number of Communities	12
Number of Nodes involved in Communities	89
Number of Links involved in Communities	128

Path Summary
Number Of Nodes in MetaPath	82
Number Of Links MetaPath	81
Number of Shortest Paths	144562
Length Of Smallest Path	3
Average Path Length	18.8383
Length of Longest Path	37
Minimum Path Strength	1.345
Average Path Strength	6.61443
Maximum Path Strength	34.7033
Minimum Path Correlation	0.7
Average Path Correlation	0.950511
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	51.9521
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.0918
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• response to light stimulus • response to stimulus • response to radiation • response to abiotic stimulus • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • biological regulation • cellular process • signal transduction • cell communication • negative adaptation of signaling pathway • import into cell • receptor internalization • negative regulation of signaling • transport • negative regulation of biological process • desensitization of G protein-coupled receptor signaling pathway • regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • vesicle-mediated transport • localization • negative regulation of cellular process • regulation of G protein-coupled receptor signaling pathway • G protein-coupled receptor internalization • regulation of signaling • negative regulation of response to stimulus • negative regulation of signal transduction • establishment of localization • regulation of response to stimulus • adaptation of signaling pathway • regulation of cell communication • G protein-coupled receptor signaling pathway • receptor-mediated endocytosis • endocytosis • cellular anatomical structure • membrane • photoreceptor inner segment • intracellular anatomical structure • cytoplasm • cytosol • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • photoreceptor inner segment • intracellular anatomical structure • cytoplasm • cytosol • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle • opsin binding • protein binding • binding • arrestin family protein binding • G protein-coupled photoreceptor activity • molecular transducer activity • photoreceptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • vitamin binding • retinal binding • isoprenoid binding • retinoid binding • lipid binding • 11-cis retinal binding • small molecule binding • G-protein alpha-subunit binding • GTPase regulator activity • enzyme regulator activity • guanyl-nucleotide exchange factor activity • nucleoside-triphosphatase regulator activity • molecular function regulator activity • cation binding • transition metal ion binding • zinc ion binding • ion binding • metal ion binding • identical protein binding • multicellular organismal process • rod bipolar cell differentiation • cellular developmental process • sensory organ development • retina development in camera-type eye • visual system development • neural retina development • neurogenesis • multicellular organism development • eye morphogenesis • neuron differentiation • cell differentiation • anatomical structure development • animal organ morphogenesis • sensory system development • system development • developmental process • camera-type eye morphogenesis • eye development • animal organ development • nervous system development • retinal bipolar neuron differentiation • glutamatergic neuron differentiation • generation of neurons • retina morphogenesis in camera-type eye • anatomical structure morphogenesis • sensory organ morphogenesis • camera-type eye development • cellular process • cellular response to stimulus • response to light stimulus • response to stimulus • cellular response to light stimulus • response to radiation • response to abiotic stimulus • cellular response to radiation • cellular response to abiotic stimulus • cellular response to environmental stimulus • regulation of cellular process • signaling • detection of abiotic stimulus • cell communication • signal transduction • detection of light stimulus • phototransduction • detection of external stimulus • regulation of biological process • biological regulation • detection of visible light • response to external stimulus • detection of stimulus • G protein-coupled receptor signaling pathway • G protein-coupled opsin signaling pathway • phototransduction, visible light • response to light intensity • podosome assembly • organelle assembly • protein-containing complex organization • membraneless organelle assembly • cellular component organization • cellular component biogenesis • organelle organization • cellular component assembly • protein-containing complex assembly • cellular component organization or biogenesis • biosynthetic process • metabolic process • macromolecule metabolic process • gene expression • macromolecule biosynthetic process • multicellular organismal-level homeostasis • homeostatic process • anatomical structure homeostasis • tissue homeostasis • retina homeostasis • photoreceptor cell maintenance • absorption of visible light • light absorption • microtubule cytoskeleton organization • microtubule-based process • cytoskeleton organization • sensory perception of light stimulus • system process • sensory perception • nervous system process • visual perception • thermoception • sensory perception of temperature stimulus • detection of temperature stimulus involved in sensory perception • response to temperature stimulus • detection of temperature stimulus involved in thermoception • detection of temperature stimulus • detection of stimulus involved in sensory perception • taxis • thermotaxis • locomotion • cell-cell junction • anchoring junction • cell junction • photoreceptor disc membrane • organelle membrane • cell periphery • protein-containing complex • plasma membrane protein complex • plasma membrane • plasma membrane signaling receptor complex • G protein-coupled receptor complex • membrane protein complex • receptor complex • sperm midpiece • 9+2 motile cilium • sperm flagellum • motile cilium • photoreceptor inner segment membrane • plasma membrane region • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • cell projection membrane • Golgi membrane • Golgi apparatus • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • outer membrane • sperm head • sperm head plasma membrane • sperm plasma membrane • rod photoreceptor outer segment
SCOP2	Domain Identifier	• G protein-coupled receptor-like
SCOP2	Family Identifier	• G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1 H:H:?2
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


Code	BMA
PDB Residues	H:H:?3
Environment Details	Open EMBL-EBI Page
Code	BMA
Name	beta-D-mannopyranose
Synonyms	beta-D-mannose; D-mannose; mannose
Identifier
Formula	C6 H12 O6
Molecular Weight	180.156
SMILES
PubChem	439680
Formal Charge	0
Total Atoms	24
Total Chiral Atoms	5
Total Bonds	24
Total Aromatic Bonds	0


Code	PLM
PDB Residues	H:H:?4
Environment Details	Open EMBL-EBI Page
Code	PLM
Name	Palmitic Acid
Synonyms	Palmitinsäure
Identifier
Formula	C16 H32 O2
Molecular Weight	256.424
SMILES
PubChem	985
Formal Charge	0
Total Atoms	50
Total Chiral Atoms	0
Total Bonds	49
Total Aromatic Bonds	0


Code	MAN
PDB Residues	H:H:?5
Environment Details	Open EMBL-EBI Page
Code	MAN
Name	alpha-D-mannopyranose
Synonyms	alpha-D-mannose; D-mannose; mannose
Identifier
Formula	C6 H12 O6
Molecular Weight	180.156
SMILES
PubChem	185698
Formal Charge	0
Total Atoms	24
Total Chiral Atoms	5
Total Bonds	24
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P02699
Sequence	>4PXF_Chain_R N G T E G P N F Y V P F S N K T G V V R S P F E A P Q Y Y L A E P W Q F S M L A A Y M F L L I M L G F P I N F L T L Y V T V Q H K K L R T P L N Y I L L N L A V A D L F M V F G G F T T T L Y T S L H G Y F V F G P T G C N L E G F F A T L G G E I A L W S L V V L A I E R Y V V V C K P M S N F R F G E N H A I M G V A F T W V M A L A C A A P P L V G W S R Y I P E G M Q C S C G I D Y Y T P H E E T N N E S F V I Y M F V V H F I I P L I V I F F C Y G Q L V F T V K E A A A Q Q Q E S A T T Q K A E K E V T R M V I I M V I A F L I C W L P Y A G V A F Y I F T H Q G S D F G P I F M T I P A F F A K T S A V Y N P V I Y I M M N K Q F R N C M V T T L C C G K N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8P13	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	5.2	2024-11-20	To be published
	8P13 (No Gprot)	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-		5.2	2024-11-20	To be published
	8P15	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	5.9	2024-11-20	To be published
	8P15 (No Gprot)	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-		5.9	2024-11-20	To be published
	6FKD	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 137349183	-	2.49	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FKC	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473039	-	2.46	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FKB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473038	-	3.03	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FKA	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473037	-	2.7	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FK9	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473036	-	2.63	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FK8	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473035	-	2.87	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FK7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473034	-	2.62	2018-04-04	doi.org/10.1073/pnas.1718084115
	6FK6	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473033	-	2.36	2018-04-04	doi.org/10.1073/pnas.1718084115
	6PH7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol	Gt(CT)	2.9	2020-07-01	To be published
	6PH7 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol		2.9	2020-07-01	To be published
	6PGS	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol	Gt(CT)	2.9	2020-07-01	To be published
	6PGS (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol		2.9	2020-07-01	To be published
	6PEL	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol	Gt(CT)	3.19	2020-06-24	To be published
	6PEL (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol		3.19	2020-06-24	To be published
	2G87	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.6	2006-09-02	doi.org/10.1002/anie.200600595
	4J4Q	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-	Gt(CT)	2.65	2013-10-30	doi.org/10.1002/anie.201302374
	4J4Q (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-		2.65	2013-10-30	doi.org/10.1002/anie.201302374
	3OAX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2011-01-19	doi.org/10.1016/j.bpj.2010.08.003
	5W0P	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.01	2017-08-09	doi.org/10.1016/j.cell.2017.07.002
	1U19	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.2	2004-10-12	doi.org/10.1016/j.jmb.2004.07.044
	1GZM	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2003-11-20	doi.org/10.1016/j.jmb.2004.08.090
	2J4Y	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2007-09-25	doi.org/10.1016/j.jmb.2007.03.007
	3AYM	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-Retinal	-	-	2.8	2011-08-17	doi.org/10.1016/j.jmb.2011.08.044
	3AYN	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	9-cis-Retinal	-	-	2.7	2011-08-17	doi.org/10.1016/j.jmb.2011.08.044
	6OY9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt/β1/γ1	3.9	2019-07-24	doi.org/10.1016/j.molcel.2019.06.007
	6OY9 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.9	2019-07-24	doi.org/10.1016/j.molcel.2019.06.007
	6OYA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt/β1/γ1	3.3	2019-07-24	doi.org/10.1016/j.molcel.2019.06.007
	6OYA (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.3	2019-07-24	doi.org/10.1016/j.molcel.2019.06.007
	4X1H	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-	Gt(CT)	2.29	2015-11-04	doi.org/10.1016/j.str.2015.09.015
	4X1H (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-		2.29	2015-11-04	doi.org/10.1016/j.str.2015.09.015
	1HZX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2001-07-04	doi.org/10.1021/bi0155091
	4BEZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.3	2013-04-24	doi.org/10.1038/embor.2013.44
	4BEY	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	2.9	2013-05-08	doi.org/10.1038/embor.2013.44
	4BEY (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		2.9	2013-05-08	doi.org/10.1038/embor.2013.44
	2Z73	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	2.5	2008-05-13	doi.org/10.1038/nature06925
	3CAP	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	doi.org/10.1038/nature07063
	3DQB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	3.2	2008-09-23	doi.org/10.1038/nature07330
	3DQB (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.2	2008-09-23	doi.org/10.1038/nature07330
	3PQR	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.85	2011-03-09	doi.org/10.1038/nature09789
	3PQR (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		2.85	2011-03-09	doi.org/10.1038/nature09789
	3PXO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	3	2011-03-09	doi.org/10.1038/nature09789
	2X72	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3	2011-03-16	doi.org/10.1038/nature09795
	2X72 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3	2011-03-16	doi.org/10.1038/nature09795
	4ZWJ	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.3	2015-07-29	doi.org/10.1038/nature14656
	4PXF	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Arrestin1 Finger Loop	2.75	2014-09-17	doi.org/10.1038/ncomms5801
	5WKT	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	3.2	2017-12-13	doi.org/10.1038/nprot.2017.135
	5WKT (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-		3.2	2017-12-13	doi.org/10.1038/nprot.2017.135
	8FCZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	doi.org/10.1038/s41467-023-40911-9
	8FD0	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	doi.org/10.1038/s41467-023-40911-9
	8FD1	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	doi.org/10.1038/s41467-023-40911-9
	9EPP	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-	chim(Gi1-CtGq)/β1/γ2	4.06	2024-10-23	doi.org/10.1038/s41467-024-53208-2
	9EPP (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-		4.06	2024-10-23	doi.org/10.1038/s41467-024-53208-2
	9EPQ	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-	chim(Gi1-CtGq)/β1/γ2	4.15	2024-10-23	doi.org/10.1038/s41467-024-53208-2
	9EPQ (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-		4.15	2024-10-23	doi.org/10.1038/s41467-024-53208-2
	6CMO	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Gi1/β1/γ2	4.5	2018-06-20	doi.org/10.1038/s41586-018-0215-y
	6CMO (No Gprot)	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-		4.5	2018-06-20	doi.org/10.1038/s41586-018-0215-y
	7MT8	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	5.8	2021-07-07	doi.org/10.1038/s41586-021-03721-x
	7MT9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	7	2021-07-07	doi.org/10.1038/s41586-021-03721-x
	7MTA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	4.1	2021-07-07	doi.org/10.1038/s41586-021-03721-x
	7MTB	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	4	2021-07-07	doi.org/10.1038/s41586-021-03721-x
	7ZBC	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	doi.org/10.1038/s41586-023-05863-6
	7ZBE	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	doi.org/10.1038/s41586-023-05863-6
	8A6C	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	doi.org/10.1038/s41586-023-05863-6
	8A6D	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	doi.org/10.1038/s41586-023-05863-6
	8A6E	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	doi.org/10.1038/s41586-023-05863-6
	5DGY	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	7.7	2016-03-23	doi.org/10.1038/sdata.2016.21
	2HPY	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.8	2006-08-22	doi.org/10.1073/pnas.0601765103
	2I35	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.8	2006-10-17	doi.org/10.1073/pnas.0608022103
	2I36	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.1	2006-10-17	doi.org/10.1073/pnas.0608022103
	2I37	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.15	2006-10-17	doi.org/10.1073/pnas.0608022103
	1L9H	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2002-05-15	doi.org/10.1073/pnas.082666399
	4A4M	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3.3	2012-01-25	doi.org/10.1073/pnas.1114089108
	4A4M (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.3	2012-01-25	doi.org/10.1073/pnas.1114089108
	5TE3	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	-	2.7	2017-03-15	doi.org/10.1073/pnas.1617446114
	5TE5	A	Sensory	Opsins	Rhodopsin	Bos taurus	20-Methanoretinal	-	-	4.01	2017-03-15	doi.org/10.1073/pnas.1617446114
	6I9K	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	9-cis-Retinal	-	-	2.15	2019-07-03	doi.org/10.1073/pnas.1902192116
	2ZIY	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	3.7	2008-05-06	doi.org/10.1074/jbc.C800040200
	6OFJ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	doi.org/10.1074/jbc.RA119.010089
	3C9L	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2008-08-05	doi.org/10.1107/S0907444908017162
	3C9M	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2008-08-05	doi.org/10.1107/S0907444908017162
	6FUF	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Go	3.12	2018-10-03	doi.org/10.1126/sciadv.aat7052
	6FUF (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.12	2018-10-03	doi.org/10.1126/sciadv.aat7052
	1F88	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2000-08-04	doi.org/10.1126/science.289.5480.739
	4WW3	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-Retinal	-	-	2.8	2015-06-17	doi.org/10.1371/journal.pone.0126970
	5DYS	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.3	2016-08-10	doi.org/10.15252/embr.201642671
	5EN0	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.81	2016-08-10	doi.org/10.15252/embr.201642671
	5EN0 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		2.81	2016-08-10	doi.org/10.15252/embr.201642671
	2PED	A	Sensory	Opsins	Rhodopsin	Bos taurus	9-cis-Retinal	-	-	2.95	2007-10-30	doi.org/10.1529/biophysj.107.108225
	6QNO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gi1/β1/γ1	4.38	2019-07-10	doi.org/10.7554/eLife.46041
	6QNO (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4.38	2019-07-10	doi.org/10.7554/eLife.46041
	9EPR	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	Retinal	-	Gi1/β1/γ2	4.9	2024-10-30	doi.org/10.1038/s41467-024-53208-2
	9EPR (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	Retinal	-		4.9	2024-10-30	doi.org/10.1038/s41467-024-53208-2
	6NWE	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	2.71	2020-02-12	To be published
	6NWE (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-		2.71	2020-02-12	To be published
	8P12	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	3.21	2024-11-20	To be published
	8P12 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.21	2024-11-20	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 4PXF.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.