psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E138	R:R:P137	12.58	No	No	0	2	3
2	R:R:L144	R:R:Q140	9.32	No	Yes	0	6	4
3	R:R:I382	R:R:Q140	4.12	No	Yes	0	4	4
4	R:R:F143	R:R:I147	3.77	No	No	0	4	6
5	R:R:F385	R:R:L144	7.31	No	No	0	6	6
6	R:R:T149	R:R:Y145	11.24	No	No	0	7	5
7	R:R:D198	R:R:Y145	10.34	No	No	0	7	5
8	R:R:Y148	R:R:Y152	14.89	No	Yes	4	7	7
9	R:R:V194	R:R:Y148	5.05	No	No	4	7	7
10	R:R:L388	R:R:Y148	5.86	No	No	0	7	7
11	R:R:G151	R:R:S392	3.71	No	No	4	8	9
12	R:R:F393	R:R:G151	9.03	No	No	4	7	8
13	R:R:R190	R:R:Y152	5.14	Yes	Yes	0	8	7
14	R:R:V194	R:R:Y152	16.4	No	Yes	4	7	7
15	R:R:S392	R:R:Y152	5.09	No	Yes	4	9	7
16	R:R:L154	R:R:L396	4.15	No	No	0	5	7
17	R:R:G395	R:R:S155	3.71	No	No	0	9	9
18	R:R:L396	R:R:S155	3	No	No	0	7	9
19	R:R:F156	R:R:V160	6.55	No	No	0	7	3
20	R:R:F156	R:R:L192	6.09	No	No	0	7	3
21	R:R:F156	R:R:F195	5.36	No	No	0	7	7
22	R:R:F184	R:R:L159	4.87	No	No	0	8	9
23	R:R:I188	R:R:L159	4.28	No	No	0	7	9
24	R:R:A399	R:R:L159	3.15	No	No	0	8	9
25	R:R:F404	R:R:I161	3.77	No	No	0	8	4
26	R:R:A162	R:R:C403	3.61	No	No	0	9	9
27	R:R:F169	R:R:I165	3.77	Yes	Yes	2	7	8
28	R:R:C403	R:R:I165	4.91	No	Yes	0	9	8
29	R:R:I165	R:R:V409	3.07	Yes	Yes	0	8	9
30	R:R:F413	R:R:I165	7.54	No	Yes	2	5	8
31	R:R:L166	R:R:N177	9.61	No	Yes	0	8	9
32	R:R:L166	R:R:L181	8.3	No	No	0	8	6
33	R:R:F184	R:R:L166	4.87	No	No	0	8	8
34	R:R:L167	R:R:L181	4.15	No	No	0	3	6
35	R:R:F169	R:R:L172	4.87	Yes	Yes	2	7	9
36	R:R:E412	R:R:F169	13.99	Yes	Yes	2	8	7
37	R:R:F169	R:R:F413	9.65	Yes	No	2	7	5
38	R:R:H173	R:R:R170	6.77	No	No	0	7	8
39	R:R:E412	R:R:H171	11.08	Yes	No	2	8	7
40	R:R:H171	R:R:K415	9.17	No	No	2	7	7
41	R:R:L172	R:R:N177	4.12	Yes	Yes	2	9	9
42	R:R:L172	R:R:V409	4.47	Yes	Yes	0	9	9
43	R:R:E412	R:R:L172	3.98	Yes	Yes	2	8	9
44	R:R:H173	R:R:Y178	8.71	No	No	0	7	6
45	R:R:C174	R:R:R176	4.18	No	Yes	2	8	9
46	R:R:C174	R:R:N177	4.72	No	Yes	2	8	9
47	R:R:T175	R:R:Y250	6.24	No	Yes	0	7	8
48	R:R:N177	R:R:R176	12.05	Yes	Yes	2	9	9
49	R:R:R176	R:R:Y250	5.14	Yes	Yes	0	9	8
50	R:R:L349	R:R:R176	6.07	No	Yes	0	9	9
51	R:R:N406	R:R:R176	3.62	Yes	Yes	0	9	9
52	R:R:E247	R:R:I179	5.47	Yes	No	0	9	8
53	R:R:I179	R:R:Y250	6.04	No	Yes	0	8	8
54	R:R:E247	R:R:H180	11.08	Yes	No	3	9	9
55	R:R:H180	R:R:Y402	17.42	No	Yes	3	9	8
56	R:R:N182	R:R:W243	19.21	No	Yes	5	9	9
57	R:R:N182	R:R:W274	7.91	No	Yes	5	9	9
58	R:R:F187	R:R:L183	4.87	Yes	No	5	8	9
59	R:R:L183	R:R:W243	3.42	No	Yes	5	9	9
60	R:R:L183	R:R:V398	2.98	No	No	5	9	9
61	R:R:N240	R:R:S186	7.45	No	No	0	9	9
62	R:R:F187	R:R:N240	22.96	Yes	No	0	8	9
63	R:R:F187	R:R:Q394	4.68	Yes	No	0	8	9
64	R:R:F187	R:R:G395	6.02	Yes	No	0	8	9
65	R:R:F187	R:R:V398	5.24	Yes	No	5	8	9
66	R:R:C236	R:R:R190	4.18	No	Yes	0	5	8
67	R:R:R190	R:R:V237	7.85	Yes	No	0	8	6
68	R:R:N240	R:R:R190	6.03	No	Yes	0	9	8
69	R:R:Q394	R:R:R190	5.84	No	Yes	0	9	8
70	R:R:A191	R:R:F195	4.16	No	No	0	7	7
71	R:R:C193	R:R:V229	3.42	No	No	0	6	7
72	R:R:C193	R:R:L232	4.76	No	No	0	6	5
73	R:R:?233	R:R:C193	9.11	Yes	No	0	6	6
74	R:R:F196	R:R:V229	6.55	No	No	0	5	7
75	R:R:K197	R:R:Y220	5.97	No	Yes	0	6	3
76	R:R:A200	R:R:Y220	5.34	No	Yes	0	4	3
77	R:R:L201	R:R:Y220	3.52	No	Yes	0	7	3
78	R:R:D222	R:R:S219	7.36	No	No	0	6	5
79	R:R:S223	R:R:Y220	3.82	No	Yes	0	4	3
80	R:R:C226	R:R:Y220	16.13	No	Yes	0	9	3
81	R:R:G295	R:R:Q221	3.29	No	Yes	0	4	4
82	R:R:C296	R:R:Q221	4.58	No	Yes	0	9	4
83	R:R:L224	R:R:L228	4.15	No	No	0	3	4
84	R:R:C226	R:R:C296	7.28	No	No	0	9	9
85	R:R:D293	R:R:R227	17.87	No	No	1	7	8
86	R:R:G295	R:R:R227	3	No	No	0	4	8
87	R:R:R227	R:R:W297	12	No	Yes	1	8	8
88	R:R:F230	R:R:Q234	7.03	No	Yes	1	5	7
89	R:R:F230	R:R:W284	5.01	No	Yes	1	5	8
90	R:R:F230	R:R:W297	4.01	No	Yes	1	5	8
91	R:R:L231	R:R:V281	2.98	No	No	0	5	6
92	R:R:?233	R:R:Q234	4.36	Yes	Yes	0	6	7
93	R:R:?233	R:R:C236	3.9	Yes	No	0	6	5
94	R:R:?233	R:R:V237	6.11	Yes	No	0	6	6
95	R:R:Q234	R:R:W284	3.29	Yes	Yes	1	7	8
96	R:R:I309	R:R:Q234	6.86	No	Yes	1	7	7
97	R:R:W274	R:R:Y235	6.75	Yes	No	0	9	9
98	R:R:L278	R:R:Y235	4.69	No	No	0	3	9
99	R:R:A238	R:R:P277	3.74	No	Yes	0	6	9
100	R:R:I313	R:R:Y241	8.46	No	No	7	7	8
101	R:R:E364	R:R:Y241	6.73	Yes	No	7	8	8
102	R:R:V276	R:R:Y242	8.83	No	Yes	6	3	6
103	R:R:P277	R:R:Y242	6.95	Yes	Yes	6	9	6
104	R:R:F280	R:R:Y242	5.16	No	Yes	0	5	6
105	R:R:A316	R:R:Y242	6.67	No	Yes	0	7	6
106	R:R:V246	R:R:W243	3.68	No	Yes	0	8	9
107	R:R:V270	R:R:W243	4.9	No	Yes	0	5	9
108	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
109	R:R:W243	R:R:W274	20.62	Yes	Yes	5	9	9
110	R:R:L244	R:R:N320	4.12	No	No	0	9	9
111	R:R:L245	R:R:V249	2.98	No	No	0	8	6
112	R:R:L245	R:R:V319	4.47	No	No	0	8	6
113	R:R:L245	R:R:N320	5.49	No	No	0	8	9
114	R:R:V246	R:R:Y269	10.09	No	No	0	8	7
115	R:R:I272	R:R:V246	3.07	No	No	0	6	8
116	R:R:E247	R:R:T353	4.23	Yes	Yes	3	9	9
117	R:R:E247	R:R:Y402	15.71	Yes	Yes	3	9	8
118	R:R:L254	R:R:Y250	5.86	No	Yes	0	8	8
119	R:R:L251	R:R:V327	5.96	Yes	No	0	9	9
120	R:R:L251	R:R:L349	4.15	Yes	No	0	9	9
121	R:R:A350	R:R:L251	3.15	No	Yes	0	8	9
122	R:R:L251	R:R:T353	4.42	Yes	Yes	0	9	9
123	R:R:R326	R:R:Y252	6.17	No	No	0	8	8
124	R:R:L255	R:R:V327	4.47	No	No	0	8	9
125	R:R:I330	R:R:L255	5.71	No	No	0	9	8
126	R:R:L255	R:R:V331	2.98	No	No	0	8	8
127	R:R:E262	R:R:W264	10.9	No	No	0	6	5
128	R:R:I265	R:R:W264	10.57	No	No	0	5	5
129	R:R:I265	R:R:Y269	6.04	No	No	0	5	7
130	R:R:F266	R:R:V270	3.93	No	No	0	6	5
131	R:R:I272	R:R:V276	3.07	No	No	0	6	3
132	R:R:P277	R:R:V276	3.53	Yes	No	6	9	3
133	R:R:F280	R:R:P312	21.67	No	No	0	5	8
134	R:R:P283	R:R:V282	5.3	No	No	0	5	3
135	R:R:G285	R:R:W284	5.63	No	Yes	0	5	8
136	R:R:K288	R:R:W284	11.6	Yes	Yes	1	8	8
137	R:R:W284	R:R:W297	3.75	Yes	Yes	1	8	8
138	R:R:I309	R:R:W284	15.27	No	Yes	1	7	8
139	R:R:V287	R:R:Y305	6.31	No	Yes	0	4	4
140	R:R:E292	R:R:K288	18.9	No	Yes	1	6	8
141	R:R:K288	R:R:W297	11.6	Yes	Yes	1	8	8
142	R:R:K288	R:R:N300	11.19	Yes	No	0	8	6
143	R:R:L290	R:R:Y289	3.52	No	No	0	3	3
144	R:R:W297	R:R:Y289	3.86	Yes	No	0	8	3
145	R:R:Y291	R:R:Y305	7.94	No	Yes	0	3	4
146	R:R:E292	R:R:N302	14.46	No	No	1	6	5
147	R:R:E292	R:R:Y305	6.73	No	Yes	1	6	4
148	R:R:D293	R:R:W297	6.7	No	Yes	1	7	8
149	R:R:E294	R:R:R299	8.14	No	No	0	4	4
150	R:R:M371	R:R:S301	3.07	No	No	0	7	3
151	R:R:M303	R:R:N302	7.01	No	No	1	5	5
152	R:R:N302	R:R:Y305	9.3	No	Yes	1	5	4
153	R:R:M303	R:R:Y305	7.18	No	Yes	1	5	4
154	R:R:L307	R:R:N304	5.49	No	No	0	7	3
155	R:R:L307	R:R:W306	12.53	No	No	0	7	6
156	R:R:L307	R:R:L311	5.54	No	No	0	7	4
157	R:R:E364	R:R:R310	5.82	Yes	No	0	8	6
158	R:R:E364	R:R:I313	5.47	Yes	No	7	8	7
159	R:R:I318	R:R:L314	7.14	No	No	0	4	4
160	R:R:A368	R:R:L314	3.15	No	No	0	6	4
161	R:R:F315	R:R:V319	3.93	No	No	0	4	6
162	R:R:C317	R:R:C361	7.28	No	No	0	7	9
163	R:R:C317	R:R:E364	3.04	No	Yes	0	7	8
164	R:R:C361	R:R:N320	3.15	No	No	0	9	9
165	R:R:F324	R:R:I328	7.54	Yes	No	0	9	7
166	R:R:F324	R:R:L354	7.31	Yes	No	0	9	8
167	R:R:F324	R:R:I357	5.02	Yes	No	3	9	8
168	R:R:F324	R:R:P358	10.11	Yes	No	3	9	9
169	R:R:I330	R:R:R326	5.01	No	No	0	9	8
170	R:R:L354	R:R:V327	5.96	No	No	0	8	9
171	R:R:L335	R:R:V331	2.98	No	No	0	8	8
172	R:R:K334	R:R:M340	5.76	No	No	0	9	5
173	R:R:F347	R:R:L335	4.87	Yes	No	0	7	8
174	R:R:A337	R:R:L339	3.15	No	No	0	7	7
175	R:R:F347	R:R:M340	3.73	Yes	No	0	7	5
176	R:R:F347	R:R:K342	13.65	Yes	No	0	7	5
177	R:R:E408	R:R:I345	4.1	No	No	0	9	5
178	R:R:F347	R:R:K351	11.17	Yes	No	8	7	8
179	R:R:F347	W:W:?1	3.32	Yes	Yes	8	7	0
180	R:R:N407	R:R:R348	15.67	No	Yes	0	6	8
181	R:R:E408	R:R:R348	10.47	No	Yes	0	9	8
182	R:R:R348	W:W:?1	8.27	Yes	Yes	0	8	0
183	R:R:K351	W:W:?1	25.91	No	Yes	8	8	0
184	R:R:L401	R:R:S352	6.01	No	No	0	8	9
185	R:R:S352	R:R:Y402	5.09	No	Yes	0	9	8
186	R:R:S352	W:W:?1	8.17	No	Yes	0	9	0
187	R:R:I357	R:R:T353	3.04	No	Yes	3	8	9
188	R:R:T353	R:R:Y402	6.24	Yes	Yes	3	9	8
189	R:R:L354	W:W:?1	4.71	No	Yes	0	8	0
190	R:R:T355	W:W:?1	19.06	No	Yes	0	8	0
191	R:R:L356	R:R:V398	2.98	Yes	No	0	9	9
192	R:R:L356	R:R:L401	4.15	Yes	No	0	9	8
193	R:R:L356	R:R:Y402	5.86	Yes	Yes	0	9	8
194	R:R:I357	R:R:P358	3.39	No	No	3	8	9
195	R:R:I366	R:R:T362	3.04	No	No	0	6	7
196	R:R:F367	R:R:H363	9.05	No	No	0	7	8
197	R:R:E387	R:R:H363	13.54	No	No	0	8	8
198	R:R:F367	R:R:I366	10.05	No	No	0	7	6
199	R:R:F367	R:R:V370	3.93	No	No	0	7	5
200	R:R:L384	R:R:R380	6.07	No	No	0	5	5
201	R:R:K383	R:R:T386	9.01	No	No	0	7	4
202	R:R:F390	R:R:S389	3.96	No	No	0	6	5
203	R:R:F393	R:R:S392	5.28	No	No	4	7	9
204	R:R:I400	R:R:L396	4.28	No	No	0	6	7
205	R:R:L401	R:R:M397	4.24	No	No	0	8	5
206	R:R:F404	R:R:I400	5.02	No	No	0	8	6
207	R:R:V405	W:W:?1	10.14	No	Yes	0	6	0
208	R:R:E408	R:R:N406	11.83	No	Yes	0	9	9
209	R:R:N406	R:R:V409	7.39	Yes	Yes	0	9	9
210	R:R:N406	W:W:?1	6.54	Yes	Yes	0	9	0
211	R:R:E412	R:R:K415	8.1	Yes	No	2	8	7
212	R:R:K415	R:R:R419	6.19	No	No	0	7	7
213	R:R:E418	R:R:W417	4.36	No	No	0	4	5
214	R:R:E418	R:R:L422	3.98	No	No	0	4	4
215	R:R:F321	R:R:P358	2.89	Yes	No	0	6	9
216	R:R:E139	R:R:S136	2.87	No	No	0	2	1
217	R:R:I188	R:R:L192	2.85	No	No	0	7	3
218	R:R:L359	R:R:M397	2.83	No	No	0	9	5
219	R:R:K334	R:R:L339	2.82	No	No	0	9	7
220	R:R:C361	R:R:F321	2.79	No	Yes	0	9	6
221	R:R:A158	R:R:F404	2.77	No	No	0	7	8
222	R:R:L189	R:R:L192	2.77	No	No	0	7	3
223	R:R:L244	R:R:L360	2.77	No	No	0	9	9
224	R:R:L356	R:R:L360	2.77	Yes	No	0	9	9
225	R:R:L359	R:R:L360	2.77	No	No	0	9	9
226	R:R:A368	R:R:F369	2.77	No	No	0	6	4
227	R:R:F280	R:R:V281	2.62	No	No	0	5	6
228	R:R:F321	R:R:V365	2.62	Yes	No	0	6	6
229	R:R:A185	R:R:W274	2.59	No	Yes	0	3	9
230	R:R:A239	R:R:W274	2.59	No	Yes	0	8	9
231	R:R:F321	R:R:T362	2.59	Yes	No	0	6	7
232	R:R:R348	R:R:T343	2.59	Yes	No	0	8	5
233	R:R:K383	R:R:R380	2.48	No	No	0	7	5
234	R:R:F369	R:R:L311	2.44	No	No	0	4	4
235	R:R:I308	R:R:W284	2.35	No	Yes	0	8	8
236	R:R:F143	R:R:Q140	2.34	No	Yes	0	4	4
237	R:R:L224	R:R:Y289	2.34	No	No	0	3	3
238	R:R:F381	R:R:F385	2.14	No	No	0	4	6
239	R:R:F266	R:R:Y178	2.06	No	No	0	6	6
240	R:R:G275	R:R:P277	2.03	No	Yes	0	6	9
241	R:R:R310	R:R:W306	2	No	No	0	6	6
242	R:R:G248	R:R:T353	1.82	No	Yes	0	8	9
243	R:R:P137	R:R:S136	1.78	No	No	0	3	1
244	R:R:G248	R:R:I323	1.76	No	No	0	8	8
245	R:R:G168	R:R:L167	1.71	No	No	0	1	3
246	R:R:I308	R:R:P283	1.69	No	No	0	8	5
247	R:R:C341	R:R:T343	1.69	No	No	0	4	5
248	R:R:A346	R:R:M340	1.61	No	No	0	6	5
249	R:R:C341	R:R:D344	1.56	No	No	0	4	7
250	R:R:I147	R:R:S389	1.55	No	No	0	6	5
251	R:R:I188	R:R:S163	1.55	No	No	0	7	6
252	R:R:I146	R:R:V150	1.54	No	No	0	4	5
253	R:R:I328	R:R:V332	1.54	No	No	0	7	6
254	R:R:Q221	R:R:S219	1.44	Yes	No	0	4	5
255	R:R:I272	R:R:L268	1.43	No	No	0	6	2
256	R:R:I286	R:R:L290	1.43	No	No	0	4	3
257	R:R:I318	R:R:L322	1.43	No	No	0	4	5
258	R:R:Q410	R:R:V409	1.43	No	Yes	0	7	9
259	R:R:Q221	R:R:T298	1.42	Yes	No	0	4	5
260	R:R:E387	R:R:T391	1.41	No	No	0	8	6
261	R:R:C329	R:R:R326	1.39	No	No	0	7	8
262	R:R:D372	R:R:M371	1.39	No	No	0	5	7
263	R:R:D198	R:R:L201	1.36	No	No	0	7	7
264	R:R:E387	R:R:L384	1.33	No	No	0	8	5
265	R:R:F169	R:R:S416	1.32	Yes	No	0	7	5
266	R:R:F393	R:R:V150	1.31	No	No	0	7	5
267	R:R:F324	R:R:V325	1.31	Yes	No	0	9	5
268	R:R:E139	R:R:Q140	1.27	No	Yes	0	2	4
269	R:R:T253	R:R:Y269	1.25	No	No	0	7	7
270	R:R:F385	R:R:L388	1.22	No	No	0	6	7
271	R:R:Q410	R:R:R414	1.17	No	No	0	7	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Q140	4.2625	4	0	4
2	R:R:Y152	10.38	4	4	7
3	R:R:I165	4.8225	4	2	8
4	R:R:F169	6.72	5	2	7
5	R:R:L172	4.36	4	2	9
6	R:R:R176	6.212	5	2	9
7	R:R:N177	7.625	4	2	9
8	R:R:F187	8.754	5	5	8
9	R:R:R190	5.808	5	0	8
10	R:R:Y220	6.956	5	0	3
11	R:R:Q221	2.6825	4	0	4
12	R:R:?233	5.87	4	0	6
13	R:R:Q234	5.385	4	1	7
14	R:R:Y242	6.9025	4	6	6
15	R:R:W243	10.045	6	5	9
16	R:R:E247	9.1225	4	3	9
17	R:R:Y250	5.82	4	0	8
18	R:R:L251	4.42	4	0	9
19	R:R:W274	8.092	5	5	9
20	R:R:P277	4.0625	4	6	9
21	R:R:W284	6.7	7	1	8
22	R:R:K288	13.3225	4	1	8
23	R:R:W297	6.98667	6	1	8
24	R:R:Y305	7.492	5	1	4
25	R:R:F321	2.7225	4	0	6
26	R:R:F324	6.258	5	3	9
27	R:R:F347	7.348	5	8	7
28	R:R:R348	9.25	4	0	8
29	R:R:T353	3.95	5	3	9
30	R:R:L356	3.94	4	0	9
31	R:R:E364	5.265	4	7	8
32	R:R:Y402	10.064	5	3	8
33	R:R:N406	7.345	4	0	9
34	R:R:V409	4.09	4	0	9
35	R:R:E412	9.2875	4	2	8
36	W:W:?1	10.765	8	8	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F385	R:R:L388	10.8566	1.22	No	No	0	6	7
2	R:R:L388	R:R:Y148	11.6751	5.86	No	No	0	7	7
3	R:R:Y148	R:R:Y152	12.4733	14.89	No	Yes	4	7	7
4	R:R:R190	R:R:Y152	18.137	5.14	Yes	Yes	0	8	7
5	R:R:C236	R:R:R190	46.4423	4.18	No	Yes	0	5	8
6	R:R:?233	R:R:C236	45.8377	3.9	Yes	No	0	6	5
7	R:R:?233	R:R:Q234	85.2887	4.36	Yes	Yes	0	6	7
8	R:R:F230	R:R:Q234	32.4826	7.03	No	Yes	1	5	7
9	R:R:F230	R:R:W297	31.136	4.01	No	Yes	1	5	8
10	R:R:R227	R:R:W297	43.6045	12	No	Yes	1	8	8
11	R:R:G295	R:R:R227	40.9686	3	No	No	0	4	8
12	R:R:G295	R:R:Q221	38.1941	3.29	No	Yes	0	4	4
13	R:R:C296	R:R:Q221	27.0722	4.58	No	Yes	0	9	4
14	R:R:C226	R:R:C296	24.2858	7.28	No	No	0	9	9
15	R:R:C226	R:R:Y220	21.4969	16.13	No	Yes	0	9	3
16	R:R:L201	R:R:Y220	10.7634	3.52	No	Yes	0	7	3
17	R:R:R190	R:R:V237	46.4423	7.85	Yes	No	0	8	6
18	R:R:?233	R:R:V237	45.8377	6.11	Yes	No	0	6	6
19	R:R:Q234	R:R:W284	50.2133	3.29	Yes	Yes	1	7	8
20	R:R:W284	R:R:W297	31.1443	3.75	Yes	Yes	1	8	8
21	R:R:N240	R:R:R190	52.2147	6.03	No	Yes	0	9	8
22	R:R:F187	R:R:N240	52.4847	22.96	Yes	No	0	8	9
23	R:R:Q394	R:R:R190	52.0223	5.84	No	Yes	0	9	8
24	R:R:F187	R:R:Q394	52.1573	4.68	Yes	No	0	8	9
25	R:R:F187	R:R:V398	91.3037	5.24	Yes	No	5	8	9
26	R:R:L356	R:R:V398	100	2.98	Yes	No	0	9	9
27	R:R:L356	R:R:L401	26.6229	4.15	Yes	No	0	9	8
28	R:R:L401	R:R:S352	25.9789	6.01	No	No	0	8	9
29	R:R:S352	W:W:?1	51.1238	8.17	No	Yes	0	9	0
30	R:R:N406	W:W:?1	35.183	6.54	Yes	Yes	0	9	0
31	R:R:N406	R:R:R176	17.8406	3.62	Yes	Yes	0	9	9
32	R:R:N177	R:R:R176	31.2674	12.05	Yes	Yes	2	9	9
33	R:R:L166	R:R:N177	29.4846	9.61	No	Yes	0	8	9
34	R:R:F184	R:R:L166	21.6702	4.87	No	No	0	8	8
35	R:R:F184	R:R:L159	19.7261	4.87	No	No	0	8	9
36	R:R:I188	R:R:L159	15.7998	4.28	No	No	0	7	9
37	R:R:I188	R:R:L192	11.8639	2.85	No	No	0	7	3
38	R:R:L356	R:R:Y402	59.1031	5.86	Yes	Yes	0	9	8
39	R:R:S352	R:R:Y402	26.1127	5.09	No	Yes	0	9	8
40	R:R:E247	R:R:Y402	10.4253	15.71	Yes	Yes	3	9	8
41	R:R:E247	R:R:I179	10.2054	5.47	Yes	No	0	9	8
42	R:R:T353	R:R:Y402	22.4242	6.24	Yes	Yes	3	9	8
43	R:R:L251	R:R:T353	13.612	4.42	Yes	Yes	0	9	9
44	R:R:N406	R:R:V409	15.1378	7.39	Yes	Yes	0	9	9
45	R:R:F187	R:R:L183	12.6883	4.87	Yes	No	5	8	9
46	R:R:L183	R:R:W243	20.9043	3.42	No	Yes	5	9	9
47	R:R:W297	R:R:Y289	13.7793	3.86	Yes	No	0	8	3
48	R:R:V246	R:R:W243	12.3586	3.68	No	Yes	0	8	9
49	R:R:L356	R:R:L360	17.2898	2.77	Yes	No	0	9	9
50	R:R:L244	R:R:L360	16.2885	2.77	No	No	0	9	9
51	R:R:L244	R:R:N320	15.6827	4.12	No	No	0	9	9
52	R:R:C361	R:R:N320	13.2093	3.15	No	No	0	9	9
53	R:R:K288	R:R:W284	12.5055	11.6	Yes	Yes	1	8	8
54	R:R:F321	R:R:T362	11.2557	2.59	Yes	No	0	6	7
55	R:R:I366	R:R:T362	10.2281	3.04	No	No	0	6	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:N406	R:R:R176	3.62	0	Yes	Yes	9	9	1	2
R:R:F324	R:R:L354	7.31	3	Yes	No	9	8	2	1
R:R:L354	R:R:V327	5.96	0	No	No	8	9	1	2
R:R:F347	R:R:L335	4.87	8	Yes	No	7	8	1	2
R:R:F347	R:R:M340	3.73	8	Yes	No	7	5	1	2
R:R:F347	R:R:K342	13.65	8	Yes	No	7	5	1	2
R:R:F347	R:R:K351	11.17	8	Yes	No	7	8	1	1
R:R:F347	W:W:?1	3.32	8	Yes	Yes	7	0	1	0
R:R:N407	R:R:R348	15.67	0	No	Yes	6	8	2	1
R:R:E408	R:R:R348	10.47	0	No	Yes	9	8	2	1
R:R:R348	W:W:?1	8.27	0	Yes	Yes	8	0	1	0
R:R:K351	W:W:?1	25.91	8	No	Yes	8	0	1	0
R:R:L401	R:R:S352	6.01	0	No	No	8	9	2	1
R:R:S352	R:R:Y402	5.09	0	No	Yes	9	8	1	2
R:R:S352	W:W:?1	8.17	0	No	Yes	9	0	1	0
R:R:L354	W:W:?1	4.71	0	No	Yes	8	0	1	0
R:R:T355	W:W:?1	19.06	0	No	Yes	8	0	1	0
R:R:V405	W:W:?1	10.14	0	No	Yes	6	0	1	0
R:R:E408	R:R:N406	11.83	0	No	Yes	9	9	2	1
R:R:N406	R:R:V409	7.39	0	Yes	Yes	9	9	1	2
R:R:N406	W:W:?1	6.54	0	Yes	Yes	9	0	1	0
R:R:R348	R:R:T343	2.59	0	Yes	No	8	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
77.78	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
70.00	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
66.67	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
63.64	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
58.33	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
50.00	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
36.36	Consensus	gi_gaba	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
29.41	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
27.27	Single	7EB2	rac-BHFF	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
27.27	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
27.27	Consensus	gabab_on	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
27.27	Consensus	gi_class-c	Other Ligand	gi_mglu gi_gaba
25.00	Single	7E14	PubChem 156022738	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
23.08	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
21.43	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
20.00	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
20.00	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
20.00	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
20.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
18.75	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
18.18	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
15.79	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
15.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
14.29	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
13.64	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
13.33	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
13.33	Consensus	nts1_on_allo	Other Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
12.50	Single	7DUR	PubChem 156022738	7DUR-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
11.11	Single	7EVM	PubChem 156022738	7EVM-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
11.11	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/&β;1/&γ;2
11.11	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
10.53	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
10.00	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
10.00	Consensus	ccr9_off_allo	Other Ligand	5LWE-CCR9-Vercirnon
9.09	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
8.33	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
6.25	Single	8HNN	SCH546738	8HNN-CXCR3-SCH546738
5.88	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/&β;1/&γ;2
5.56	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996

PDB Summary
PDB	5VEX
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GLP-1
Species	Homo sapiens
Ligand	-
Other Ligand(s)	NNC0640
Protein Partners	-
PDB Resolution	3
Date	2017-05-17
D.O.I.	10.1038/nature22378

Net Summary
I_min	2.98
Number of Linked Nodes	241
Number of Links	271
Number of Hubs	36
Number of Links mediated by Hubs	139
Number of Communities	8
Number of Nodes involved in Communities	50
Number of Links involved in Communities	63

Path Summary
Number Of Nodes in MetaPath	56
Number Of Links MetaPath	55
Number of Shortest Paths	112639
Length Of Smallest Path	3
Average Path Length	17.5537
Length of Longest Path	35
Minimum Path Strength	1.3
Average Path Strength	6.00045
Maximum Path Strength	22.485
Minimum Path Correlation	0.7
Average Path Correlation	0.932883
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	39.3965
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.7534
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	CSD
PDB Residues	R:R:?233
Environment Details	Open EMBL-EBI Page
Code	CSD
Name	3-sulfino-L-alanine
Synonyms	3-Sulphino-L-alanine
Identifier	(2R)-2-azanyl-3-[(S)-oxidanylsulfinyl]propanoic acid
Formula	C3 H7 N O4 S
Molecular Weight	153.157
SMILES	C([C@@H](C(=O)O)N)[S@@](=O)O
PubChem	1549098
Formal Charge	0
Total Atoms	16
Total Chiral Atoms	1
Total Bonds	15
Total Aromatic Bonds	0


Code	97V
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	97V
Name	4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide
Synonyms
Identifier	4-[[(4-cyclohexylphenyl)-[(3-methylsulfonylphenyl)carbamoyl]amino]methyl]-~{N}-(1~{H}-1,2,3,4-tetrazol-5-yl)benzamide
Formula	C29 H31 N7 O4 S
Molecular Weight	573.666
SMILES	CS(=O)(=O)c1cccc(c1)NC(=O)N(Cc2ccc(cc2)C(=O)Nc3[nH]nnn3)c4ccc(cc4)C5CCCCC5
PubChem	23549991
Formal Charge	0
Total Atoms	72
Total Chiral Atoms	0
Total Bonds	76
Total Aromatic Bonds	23


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>5VEX_Chain_R S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L C V F F K D A A L K W L S Y Q D S L A C R L V F L L ?Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S E Q W I F R L Y V A I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A C I V N F L I F V R V I C I V V S K L K A N L M C K T D I A F R L A K S T L T L I P L L C T H E V I F A F V M D R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/&β;1/&γ;2	4.1	2017-05-24	10.1038/nature22394
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/&β;1/&γ;2	3.3	2018-02-21	10.1038/nature25773
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/&β;1/&γ;2	3	2020-01-08	10.1038/s41586-019-1902-z
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/&β;1/&γ;2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2020-11-18	10.1073/pnas.2014879117
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/&β;1/&γ;2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/&β;1/&γ;2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/&β;1/&γ;2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/&β;1/&γ;2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/&β;1/&γ;2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/&β;1/&γ;2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/&β;1/&γ;2	3	2022-03-02	10.1038/s41467-022-28683-0
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/&β;1/&γ;2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/&β;1/&γ;2	3.09	2022-06-29	10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.46	2023-11-08	10.1073/pnas.2303696120
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.54	2024-03-06	10.1038/s41421-024-00649-0

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