psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E9	R:R:Y148	13.47	Yes	Yes	2	0	7
2	L:L:E9	R:R:V194	5.7	Yes	Yes	2	0	7
3	L:L:E9	R:R:K197	6.75	Yes	Yes	2	0	6
4	L:L:E9	R:R:L388	3.98	Yes	Yes	2	0	7
5	L:L:G10	R:R:W306	2.81	No	Yes	0	0	6
6	L:L:T11	R:R:D372	4.34	No	No	0	0	5
7	L:L:T11	R:R:L384	4.42	No	No	0	0	5
8	L:L:F12	L:L:V16	5.24	Yes	Yes	2	0	0
9	L:L:F12	R:R:L141	4.87	Yes	No	2	0	5
10	L:L:F12	R:R:L144	3.65	Yes	No	2	0	6
11	L:L:F12	R:R:Y148	8.25	Yes	Yes	2	0	7
12	L:L:F12	R:R:L388	7.31	Yes	Yes	2	0	7
13	L:L:T13	R:R:K197	10.51	No	Yes	2	0	6
14	L:L:T13	R:R:F230	3.89	No	Yes	2	0	5
15	L:L:S14	R:R:N300	8.94	No	No	0	0	6
16	L:L:D15	R:R:R380	10.72	No	Yes	0	0	5
17	L:L:L20	L:L:V16	2.98	No	Yes	2	0	0
18	L:L:V16	R:R:L141	4.47	Yes	No	2	0	5
19	L:L:V16	R:R:L201	2.98	Yes	No	2	0	7
20	L:L:V16	W:W:?1	3.21	Yes	Yes	2	0	0
21	L:L:S17	R:R:Y205	6.36	No	Yes	0	0	3
22	L:L:S17	R:R:T298	9.59	No	No	0	0	5
23	L:L:S17	R:R:R299	5.27	No	Yes	0	0	4
24	L:L:S18	R:R:T29	6.4	No	No	0	0	2
25	L:L:Q23	L:L:Y19	7.89	No	No	0	0	0
26	L:L:Y19	R:R:E138	7.86	No	No	0	0	2
27	L:L:Y19	W:W:?1	4.21	No	Yes	0	0	0
28	L:L:L20	R:R:Y205	10.55	No	Yes	0	0	3
29	L:L:L20	W:W:?1	9.94	No	Yes	2	0	0
30	L:L:E21	R:R:S31	5.75	Yes	No	0	0	4
31	L:L:E21	R:R:Y205	14.59	Yes	Yes	0	0	3
32	L:L:E21	R:R:Q221	5.1	Yes	Yes	0	0	4
33	L:L:E21	R:R:R299	12.79	Yes	Yes	0	0	4
34	L:L:K26	L:L:Q23	14.92	No	No	0	0	0
35	L:L:A24	R:R:L32	3.15	No	Yes	0	0	4
36	L:L:A24	R:R:Q210	3.03	No	No	0	0	4
37	L:L:A25	R:R:P90	3.74	No	Yes	0	0	4
38	L:L:E27	R:R:Q210	6.37	No	No	1	0	4
39	L:L:E27	R:R:W214	3.27	No	Yes	1	0	1
40	L:L:F28	L:L:W31	3.01	Yes	No	1	0	0
41	L:L:F28	L:L:L32	10.96	Yes	No	1	0	0
42	L:L:F28	R:R:V36	6.55	Yes	No	0	0	2
43	L:L:F28	R:R:W39	9.02	Yes	Yes	1	0	5
44	L:L:F28	R:R:W214	17.04	Yes	Yes	1	0	1
45	L:L:I29	R:R:L89	2.85	No	Yes	1	0	5
46	L:L:I29	R:R:P90	5.08	No	Yes	1	0	4
47	L:L:R36	L:L:W31	13	No	No	0	0	0
48	L:L:W31	R:R:W214	20.62	No	Yes	1	0	1
49	L:L:L32	R:R:W39	7.97	No	Yes	1	0	5
50	L:L:L32	R:R:Y88	3.52	No	Yes	1	0	5
51	L:L:V33	R:R:L123	4.47	No	Yes	0	0	5
52	L:L:R36	R:R:W39	9	No	Yes	0	0	5
53	L:L:R36	R:R:E68	20.93	No	No	0	0	4
54	R:R:L32	R:R:T35	4.42	Yes	No	0	4	5
55	R:R:L32	R:R:V36	2.98	Yes	No	0	4	2
56	R:R:L32	R:R:W214	6.83	Yes	Yes	0	4	1
57	R:R:Q37	R:R:W33	16.43	No	No	0	4	3
58	R:R:K38	R:R:W87	8.12	No	Yes	0	4	3
59	R:R:R43	R:R:W39	3	Yes	Yes	0	4	5
60	R:R:W39	R:R:Y88	5.79	Yes	Yes	1	5	5
61	R:R:G216	R:R:R40	4.5	No	No	0	2	2
62	R:R:E41	R:R:R44	6.98	No	No	0	4	3
63	R:R:Q45	R:R:Y42	3.38	No	Yes	1	5	6
64	R:R:F66	R:R:Y42	4.13	No	Yes	0	7	6
65	R:R:P86	R:R:Y42	5.56	No	Yes	1	8	6
66	R:R:W87	R:R:Y42	10.61	Yes	Yes	1	3	6
67	R:R:Y42	R:R:Y88	6.95	Yes	Yes	1	6	5
68	R:R:Q47	R:R:R43	8.18	No	Yes	0	3	4
69	R:R:F66	R:R:R43	3.21	No	Yes	0	7	4
70	R:R:Q45	R:R:R48	7.01	No	No	0	5	4
71	R:R:Q45	R:R:W87	7.67	No	Yes	1	5	3
72	R:R:C46	R:R:S49	3.44	No	No	9	8	2
73	R:R:C46	R:R:F66	15.36	No	No	0	8	7
74	R:R:C46	R:R:C71	7.28	No	No	9	8	9
75	R:R:E52	R:R:R48	12.79	No	No	0	2	4
76	R:R:C71	R:R:S49	3.44	No	No	9	9	2
77	R:R:L50	R:R:R64	10.93	No	Yes	0	4	4
78	R:R:D53	R:R:P54	6.44	No	No	0	3	2
79	R:R:D53	R:R:R64	10.72	No	Yes	8	3	4
80	R:R:D53	R:R:D74	3.99	No	Yes	8	3	3
81	R:R:P55	R:R:R64	12.97	No	Yes	8	1	4
82	R:R:D74	R:R:P55	4.83	Yes	No	8	3	1
83	R:R:F61	R:R:P56	5.78	Yes	No	0	3	1
84	R:R:D74	R:R:P56	9.66	Yes	No	0	3	1
85	R:R:F61	R:R:T58	19.46	Yes	No	0	3	1
86	R:R:E76	R:R:F61	15.16	No	Yes	10	1	3
87	R:R:F61	R:R:P77	2.89	Yes	No	10	3	4
88	R:R:C104	R:R:C62	5.46	No	Yes	1	9	9
89	R:R:C62	R:R:W110	15.67	Yes	Yes	1	9	9
90	R:R:D74	R:R:N63	4.04	Yes	No	0	3	4
91	R:R:D74	R:R:R64	14.29	Yes	Yes	8	3	4
92	R:R:T65	R:R:W72	3.64	No	Yes	1	5	9
93	R:R:R102	R:R:T65	10.35	Yes	No	1	8	5
94	R:R:T65	R:R:W110	10.92	No	Yes	1	5	9
95	R:R:D67	R:R:Y69	4.6	Yes	Yes	1	9	6
96	R:R:D67	R:R:W72	10.05	Yes	Yes	1	9	9
97	R:R:D67	R:R:R102	3.57	Yes	Yes	1	9	8
98	R:R:D67	R:R:R121	7.15	Yes	No	0	9	6
99	R:R:P86	R:R:Y69	6.95	No	Yes	1	8	6
100	R:R:Y69	R:R:Y88	3.97	Yes	Yes	1	6	5
101	R:R:V100	R:R:Y69	3.79	Yes	Yes	1	7	6
102	R:R:L123	R:R:Y69	7.03	Yes	Yes	0	5	6
103	R:R:A70	R:R:W72	3.89	No	Yes	0	5	9
104	R:R:V83	R:R:W72	6.13	No	Yes	0	5	9
105	R:R:V100	R:R:W72	4.9	Yes	Yes	1	7	9
106	R:R:R102	R:R:W72	26.99	Yes	Yes	1	8	9
107	R:R:P73	R:R:V81	3.53	No	No	0	5	6
108	R:R:E76	R:R:P77	6.29	No	No	10	1	4
109	R:R:E76	R:R:S79	8.62	No	No	0	1	5
110	R:R:F103	R:R:G78	4.52	Yes	No	0	4	7
111	R:R:F103	R:R:F80	35.37	Yes	No	1	4	4
112	R:R:F80	R:R:W120	5.01	No	Yes	1	4	5
113	R:R:H99	R:R:N82	5.1	No	No	0	4	4
114	R:R:N82	R:R:Y101	10.47	No	No	0	4	5
115	R:R:H99	R:R:S84	2.79	No	No	0	4	4
116	R:R:C126	R:R:C85	7.28	No	No	0	9	9
117	R:R:P86	R:R:V100	3.53	No	Yes	1	8	7
118	R:R:L89	R:R:P90	3.28	Yes	Yes	1	5	4
119	R:R:L89	R:R:W91	13.67	Yes	Yes	1	5	4
120	R:R:P90	R:R:W91	13.51	Yes	Yes	1	4	4
121	R:R:S94	R:R:W91	6.18	No	Yes	0	4	4
122	R:R:E128	R:R:W91	10.9	No	Yes	0	3	4
123	R:R:S94	R:R:V95	4.85	No	No	0	4	5
124	R:R:E125	R:R:V100	2.85	Yes	Yes	1	5	7
125	R:R:W120	R:R:Y101	2.89	Yes	No	0	5	5
126	R:R:E125	R:R:Y101	12.35	Yes	No	0	5	5
127	R:R:R102	R:R:W110	23.99	Yes	Yes	1	8	9
128	R:R:P119	R:R:R102	14.41	No	Yes	0	6	8
129	R:R:F103	R:R:L111	14.61	Yes	No	0	4	4
130	R:R:F103	R:R:W120	6.01	Yes	Yes	1	4	5
131	R:R:C104	R:R:W110	7.84	No	Yes	1	9	9
132	R:R:E107	R:R:T105	14.11	No	No	11	5	4
133	R:R:L109	R:R:T105	5.9	No	No	11	5	4
134	R:R:L111	R:R:T105	5.9	No	No	0	4	4
135	R:R:E107	R:R:L109	9.28	No	No	11	5	5
136	R:R:N115	R:R:Q112	3.96	No	No	0	4	3
137	R:R:D114	R:R:K113	16.59	No	No	0	4	4
138	R:R:K113	R:R:W120	4.64	No	Yes	0	4	5
139	R:R:L118	R:R:S116	3	No	No	0	4	5
140	R:R:L118	R:R:P119	3.28	No	No	0	4	6
141	R:R:D122	R:R:W120	4.47	No	Yes	1	7	5
142	R:R:L123	R:R:R121	8.5	Yes	No	0	5	6
143	R:R:D122	R:R:S124	7.36	No	No	1	7	5
144	R:R:D122	R:R:E125	5.2	No	Yes	1	7	5
145	R:R:E125	R:R:S124	2.87	Yes	No	1	5	5
146	R:R:C126	R:R:E125	3.04	No	Yes	0	9	5
147	R:R:E138	R:R:S136	7.19	No	No	0	2	1
148	R:R:F381	R:R:Q140	21.08	No	No	0	4	4
149	R:R:L141	W:W:?1	2.98	No	Yes	2	5	0
150	R:R:L142	W:W:?1	17.9	No	Yes	0	3	0
151	R:R:F143	R:R:I147	8.79	No	No	0	4	6
152	R:R:F143	R:R:F385	3.22	No	No	0	4	6
153	R:R:F381	R:R:L144	3.65	No	No	0	4	6
154	R:R:L144	R:R:L388	6.92	No	Yes	2	6	7
155	R:R:I146	R:R:Y145	3.63	No	Yes	2	4	5
156	R:R:Y145	R:R:Y148	4.96	Yes	Yes	2	5	7
157	R:R:T149	R:R:Y145	8.74	No	Yes	0	7	5
158	R:R:D198	R:R:Y145	6.9	Yes	Yes	2	7	5
159	R:R:Y145	W:W:?1	37.05	Yes	Yes	2	5	0
160	R:R:I146	W:W:?1	3.08	No	Yes	2	4	0
161	R:R:I147	R:R:S389	3.1	No	No	0	6	5
162	R:R:Y148	R:R:Y152	5.96	Yes	Yes	2	7	7
163	R:R:V194	R:R:Y148	3.79	Yes	Yes	2	7	7
164	R:R:K197	R:R:Y148	3.58	Yes	Yes	2	6	7
165	R:R:D198	R:R:Y148	9.2	Yes	Yes	2	7	7
166	R:R:L388	R:R:Y148	5.86	Yes	Yes	2	7	7
167	R:R:G151	R:R:V150	3.68	No	No	0	8	5
168	R:R:L154	R:R:V150	2.98	No	No	0	5	5
169	R:R:G151	R:R:S392	3.71	No	No	0	8	9
170	R:R:F393	R:R:G151	9.03	No	No	0	7	8
171	R:R:R190	R:R:Y152	11.32	Yes	Yes	0	8	7
172	R:R:V194	R:R:Y152	11.36	Yes	Yes	2	7	7
173	R:R:S392	R:R:Y152	7.63	No	Yes	0	9	7
174	R:R:L154	R:R:L396	2.77	No	No	0	5	7
175	R:R:G395	R:R:S155	3.71	No	No	0	9	9
176	R:R:F156	R:R:V160	3.93	Yes	No	12	7	3
177	R:R:F156	R:R:I188	3.77	Yes	No	12	7	7
178	R:R:A191	R:R:F156	2.77	No	Yes	0	7	7
179	R:R:F156	R:R:L192	8.53	Yes	No	0	7	3
180	R:R:F184	R:R:L159	7.31	Yes	Yes	0	8	9
181	R:R:F187	R:R:L159	3.65	Yes	Yes	0	8	9
182	R:R:I188	R:R:L159	2.85	No	Yes	0	7	9
183	R:R:A399	R:R:L159	3.15	No	Yes	0	8	9
184	R:R:I188	R:R:V160	3.07	No	No	12	7	3
185	R:R:F404	R:R:I161	3.77	No	No	0	8	4
186	R:R:A162	R:R:F184	2.77	No	Yes	4	9	8
187	R:R:A162	R:R:C403	3.61	No	Yes	4	9	9
188	R:R:A162	R:R:F404	2.77	No	No	0	9	8
189	R:R:L181	R:R:S163	3	No	No	0	6	6
190	R:R:F184	R:R:S163	3.96	Yes	No	0	8	6
191	R:R:C403	R:R:I165	3.27	Yes	No	0	9	8
192	R:R:F413	R:R:I165	7.54	No	No	0	5	8
193	R:R:L166	R:R:L172	2.77	Yes	Yes	4	8	9
194	R:R:L166	R:R:N177	5.49	Yes	Yes	4	8	9
195	R:R:L166	R:R:L181	6.92	Yes	No	0	8	6
196	R:R:F184	R:R:L166	3.65	Yes	Yes	4	8	8
197	R:R:C403	R:R:L166	6.35	Yes	Yes	4	9	8
198	R:R:L167	R:R:L181	2.77	No	No	0	3	6
199	R:R:F169	R:R:L172	4.87	Yes	Yes	4	7	9
200	R:R:E412	R:R:F169	4.66	Yes	Yes	4	8	7
201	R:R:F169	R:R:F413	12.86	Yes	No	0	7	5
202	R:R:E412	R:R:H171	13.54	Yes	No	0	8	7
203	R:R:E408	R:R:L172	6.63	No	Yes	0	9	9
204	R:R:E412	R:R:L172	6.63	Yes	Yes	4	8	9
205	R:R:H173	R:R:Y178	10.89	No	No	0	7	6
206	R:R:E262	R:R:T175	14.11	No	No	0	6	7
207	R:R:F266	R:R:T175	3.89	No	No	0	6	7
208	R:R:N177	R:R:R176	3.62	Yes	Yes	4	9	9
209	R:R:H180	R:R:R176	4.51	Yes	Yes	4	9	9
210	R:R:R176	R:R:Y250	3.09	Yes	Yes	0	9	8
211	R:R:H180	R:R:N177	3.83	Yes	Yes	4	9	9
212	R:R:F266	R:R:Y178	6.19	No	No	0	6	6
213	R:R:I179	R:R:W243	3.52	No	Yes	0	8	9
214	R:R:I179	R:R:Y250	8.46	No	Yes	0	8	8
215	R:R:E247	R:R:H180	6.15	No	Yes	0	9	9
216	R:R:H180	R:R:Y402	6.53	Yes	No	0	9	8
217	R:R:N182	R:R:W243	14.69	No	Yes	13	9	9
218	R:R:N182	R:R:W274	4.52	No	Yes	13	9	9
219	R:R:F187	R:R:L183	7.31	Yes	No	0	8	9
220	R:R:L183	R:R:L244	2.77	No	Yes	0	9	9
221	R:R:E247	R:R:L183	15.9	No	No	0	9	9
222	R:R:F184	R:R:V398	3.93	Yes	No	0	8	9
223	R:R:C403	R:R:F184	2.79	Yes	Yes	4	9	8
224	R:R:N240	R:R:S186	4.47	Yes	No	0	9	9
225	R:R:S186	R:R:W243	4.94	No	Yes	0	9	9
226	R:R:F187	R:R:N240	14.5	Yes	Yes	0	8	9
227	R:R:F187	R:R:Q394	3.51	Yes	Yes	0	8	9
228	R:R:F187	R:R:G395	6.02	Yes	No	0	8	9
229	R:R:R190	R:R:V237	5.23	Yes	No	0	8	6
230	R:R:N240	R:R:R190	10.85	Yes	Yes	0	9	8
231	R:R:R190	R:R:Y241	5.14	Yes	Yes	0	8	8
232	R:R:R190	R:R:T391	7.76	Yes	Yes	0	8	6
233	R:R:C236	R:R:S193	6.89	No	No	0	5	6
234	R:R:I196	R:R:V229	3.07	No	No	0	5	7
235	R:R:D198	R:R:K197	6.91	Yes	Yes	2	7	6
236	R:R:F230	R:R:K197	3.72	Yes	Yes	2	5	6
237	R:R:K197	R:R:M233	4.32	Yes	No	0	6	6
238	R:R:D198	W:W:?1	2.92	Yes	Yes	2	7	0
239	R:R:A200	R:R:Y220	4	No	Yes	0	4	3
240	R:R:L201	W:W:?1	2.98	No	Yes	2	7	0
241	R:R:K202	W:W:?1	28.36	No	Yes	0	4	0
242	R:R:W203	R:R:Y220	6.75	No	Yes	0	3	3
243	R:R:M204	R:R:Y205	8.38	No	Yes	0	3	3
244	R:R:C226	R:R:M204	3.24	No	No	2	9	3
245	R:R:C296	R:R:M204	6.48	Yes	No	2	9	3
246	R:R:Q211	R:R:T207	2.83	No	No	0	4	3
247	R:R:A209	R:R:S219	3.42	No	No	0	1	5
248	R:R:Q210	R:R:W214	19.71	No	Yes	1	4	1
249	R:R:Q211	R:R:W214	4.38	No	Yes	0	4	1
250	R:R:H212	R:R:L217	14.14	No	No	0	3	4
251	R:R:Q213	R:R:S219	5.78	No	No	0	4	5
252	R:R:Q213	R:R:Q221	15.36	No	Yes	0	4	4
253	R:R:D215	R:R:G216	5.03	No	No	0	3	2
254	R:R:D222	R:R:L218	9.5	No	No	0	6	3
255	R:R:S223	R:R:Y220	3.82	No	Yes	0	4	3
256	R:R:C226	R:R:Y220	6.72	No	Yes	0	9	3
257	R:R:G295	R:R:Q221	4.93	No	Yes	0	4	4
258	R:R:L224	R:R:R227	3.64	No	No	0	3	8
259	R:R:C226	R:R:C296	7.28	No	Yes	2	9	9
260	R:R:D293	R:R:R227	8.34	No	No	3	7	8
261	R:R:R227	R:R:W297	17.99	No	Yes	3	8	8
262	R:R:F230	R:R:V229	3.93	Yes	No	0	5	7
263	R:R:C296	R:R:F230	5.59	Yes	Yes	2	9	5
264	R:R:F230	R:R:T298	7.78	Yes	No	2	5	5
265	R:R:L231	R:R:V281	2.98	No	No	0	5	6
266	R:R:G285	R:R:L231	3.42	No	No	0	5	5
267	R:R:C236	R:R:L232	3.17	No	No	0	5	5
268	R:R:M233	R:R:Q234	6.8	No	Yes	0	6	7
269	R:R:Q234	R:R:W284	9.86	Yes	Yes	3	7	8
270	R:R:Q234	R:R:W306	6.57	Yes	Yes	3	7	6
271	R:R:I309	R:R:Q234	6.86	No	Yes	3	7	7
272	R:R:W274	R:R:Y235	4.82	Yes	No	0	9	9
273	R:R:P277	R:R:Y235	4.17	Yes	No	0	9	9
274	R:R:L278	R:R:Y235	4.69	No	No	0	3	9
275	R:R:A238	R:R:F280	2.77	No	Yes	0	6	5
276	R:R:L244	R:R:N240	4.12	Yes	Yes	0	9	9
277	R:R:I313	R:R:Y241	16.92	No	Yes	5	7	8
278	R:R:I317	R:R:Y241	4.84	Yes	Yes	5	7	8
279	R:R:E364	R:R:Y241	13.47	Yes	Yes	5	8	8
280	R:R:L245	R:R:Y242	3.52	Yes	Yes	7	8	6
281	R:R:V276	R:R:Y242	5.05	No	Yes	0	3	6
282	R:R:F280	R:R:Y242	7.22	Yes	Yes	7	5	6
283	R:R:P312	R:R:Y242	4.17	No	Yes	7	8	6
284	R:R:A316	R:R:Y242	8.01	No	Yes	7	7	6
285	R:R:V246	R:R:W243	8.58	No	Yes	0	8	9
286	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
287	R:R:W243	R:R:W274	18.74	Yes	Yes	13	9	9
288	R:R:L244	R:R:Q394	3.99	Yes	Yes	0	9	9
289	R:R:A316	R:R:L245	3.15	No	Yes	7	7	8
290	R:R:L245	R:R:V319	2.98	Yes	No	0	8	6
291	R:R:L245	R:R:N320	5.49	Yes	No	0	8	9
292	R:R:V246	R:R:Y269	5.05	No	Yes	0	8	7
293	R:R:E247	R:R:L359	9.28	No	No	0	9	9
294	R:R:G248	R:R:I323	3.53	No	No	0	8	8
295	R:R:G248	R:R:L360	3.42	No	Yes	0	8	9
296	R:R:V249	R:R:Y269	3.79	No	Yes	0	6	7
297	R:R:L254	R:R:Y250	15.24	No	Yes	0	8	8
298	R:R:Y250	R:R:Y269	3.97	Yes	Yes	0	8	7
299	R:R:L251	R:R:L255	2.77	No	No	6	9	8
300	R:R:L251	R:R:V327	4.47	No	Yes	6	9	9
301	R:R:A256	R:R:Y252	5.34	No	No	0	6	8
302	R:R:I323	R:R:Y252	3.63	No	No	0	8	8
303	R:R:R326	R:R:Y252	5.14	No	No	0	8	8
304	R:R:T253	R:R:Y269	3.75	No	Yes	0	7	7
305	R:R:L255	R:R:V327	2.98	No	Yes	6	8	9
306	R:R:I330	R:R:L255	5.71	No	No	0	9	8
307	R:R:A256	R:R:F257	4.16	No	No	0	6	5
308	R:R:I265	R:R:L260	7.14	No	No	0	5	7
309	R:R:Q263	R:R:R267	11.68	No	No	0	5	4
310	R:R:I265	R:R:Y269	4.84	No	Yes	0	5	7
311	R:R:F266	R:R:V270	5.24	No	No	0	6	5
312	R:R:I272	R:R:V276	4.61	No	No	0	6	3
313	R:R:P277	R:R:V276	3.53	Yes	No	0	9	3
314	R:R:F280	R:R:P277	2.89	Yes	Yes	0	5	9
315	R:R:F280	R:R:P312	15.89	Yes	No	7	5	8
316	R:R:P283	R:R:V282	3.53	No	No	0	5	3
317	R:R:G285	R:R:W284	2.81	No	Yes	0	5	8
318	R:R:K288	R:R:W284	9.28	Yes	Yes	3	8	8
319	R:R:I308	R:R:W284	4.7	No	Yes	0	8	8
320	R:R:I309	R:R:W284	16.44	No	Yes	3	7	8
321	R:R:G285	R:R:W297	2.81	No	Yes	0	5	8
322	R:R:V287	R:R:Y305	6.31	No	No	0	4	4
323	R:R:E292	R:R:K288	4.05	No	Yes	3	6	8
324	R:R:E294	R:R:K288	5.4	Yes	Yes	3	4	8
325	R:R:K288	R:R:W297	4.64	Yes	Yes	3	8	8
326	R:R:L290	R:R:Y289	3.52	No	No	0	3	3
327	R:R:W297	R:R:Y289	3.86	Yes	No	0	8	3
328	R:R:L290	R:R:Y291	3.52	No	No	0	3	3
329	R:R:Y291	R:R:Y305	8.94	No	No	0	3	4
330	R:R:E292	R:R:E294	12.69	No	Yes	3	6	4
331	R:R:E292	R:R:S301	7.19	No	No	3	6	3
332	R:R:D293	R:R:W297	4.47	No	Yes	3	7	8
333	R:R:E294	R:R:G295	3.27	Yes	No	0	4	4
334	R:R:E294	R:R:R299	10.47	Yes	Yes	0	4	4
335	R:R:E294	R:R:S301	4.31	Yes	No	3	4	3
336	R:R:C296	R:R:T298	3.38	Yes	No	2	9	5
337	R:R:N300	R:R:W306	13.56	No	Yes	0	6	6
338	R:R:N302	R:R:N304	5.45	No	No	0	5	3
339	R:R:N302	R:R:Y305	11.63	No	No	0	5	4
340	R:R:E373	R:R:M303	12.18	No	No	0	4	5
341	R:R:I309	R:R:W306	5.87	No	Yes	3	7	6
342	R:R:R310	R:R:W306	15.99	Yes	Yes	3	6	6
343	R:R:L307	R:R:R310	9.72	No	Yes	0	7	6
344	R:R:L307	R:R:L311	2.77	No	No	0	7	4
345	R:R:M371	R:R:R310	3.72	No	Yes	3	7	6
346	R:R:E373	R:R:R310	10.47	No	Yes	3	4	6
347	R:R:I313	R:R:I317	2.94	No	Yes	5	7	7
348	R:R:L314	R:R:M371	2.83	No	No	0	4	7
349	R:R:F315	R:R:V319	6.55	No	No	0	4	6
350	R:R:G318	R:R:I317	3.53	No	Yes	0	4	7
351	R:R:A368	R:R:I317	3.25	No	Yes	0	6	7
352	R:R:F321	R:R:V325	5.24	No	No	0	6	5
353	R:R:F321	R:R:V365	15.73	No	No	0	6	6
354	R:R:F324	R:R:I328	6.28	No	Yes	6	9	7
355	R:R:F324	R:R:L356	7.31	No	Yes	6	9	9
356	R:R:F324	R:R:T362	12.97	No	No	0	9	7
357	R:R:L356	R:R:V327	2.98	Yes	Yes	6	9	9
358	R:R:I328	R:R:T353	4.56	Yes	No	0	7	9
359	R:R:I328	R:R:L356	2.85	Yes	Yes	6	7	9
360	R:R:I330	R:R:K334	2.91	No	No	0	9	9
361	R:R:L335	R:R:V331	2.98	No	No	0	8	8
362	R:R:S352	R:R:V331	3.23	No	No	0	9	8
363	R:R:L349	R:R:V332	4.47	No	No	0	9	6
364	R:R:K334	R:R:S333	4.59	No	No	0	9	7
365	R:R:L335	R:R:R348	4.86	No	No	0	8	8
366	R:R:I345	R:R:K336	4.36	No	No	0	5	6
367	R:R:K351	R:R:R348	4.95	No	No	0	8	8
368	R:R:L401	R:R:T355	7.37	No	No	0	8	8
369	R:R:T355	R:R:Y402	3.75	No	No	0	8	8
370	R:R:L356	R:R:L360	4.15	Yes	Yes	0	9	9
371	R:R:I357	R:R:P358	3.39	No	No	0	8	9
372	R:R:M397	R:R:P358	3.35	No	No	0	5	9
373	R:R:L401	R:R:P358	4.93	No	No	0	8	9
374	R:R:L359	R:R:L360	5.54	No	Yes	0	9	9
375	R:R:L359	R:R:Y402	14.07	No	No	0	9	8
376	R:R:L360	R:R:T362	2.95	Yes	No	0	9	7
377	R:R:T362	R:R:V365	3.17	No	No	0	7	6
378	R:R:E364	R:R:H363	9.85	Yes	Yes	5	8	8
379	R:R:F390	R:R:H363	7.92	No	Yes	0	6	8
380	R:R:H363	R:R:T391	5.48	Yes	Yes	5	8	6
381	R:R:H363	R:R:Q394	6.18	Yes	Yes	5	8	9
382	R:R:E364	R:R:T391	5.64	Yes	Yes	5	8	6
383	R:R:F367	R:R:I366	8.79	Yes	No	0	7	6
384	R:R:F367	R:R:I382	3.77	Yes	No	0	7	4
385	R:R:F367	R:R:K383	4.96	Yes	No	0	7	7
386	R:R:F367	R:R:T386	9.08	Yes	No	0	7	4
387	R:R:L379	R:R:V370	2.98	No	No	0	3	5
388	R:R:E373	R:R:M371	4.06	No	No	3	4	7
389	R:R:D372	R:R:R380	10.72	No	Yes	0	5	5
390	R:R:A375	R:R:L379	3.15	No	No	0	4	3
391	R:R:R376	R:R:R380	7.46	No	Yes	0	5	5
392	R:R:K383	R:R:L384	2.82	No	No	0	7	5
393	R:R:E387	R:R:K383	10.8	No	No	0	8	7
394	R:R:Q394	R:R:T391	2.83	Yes	Yes	5	9	6
395	R:R:I400	R:R:L396	4.28	No	No	0	6	7
396	R:R:L411	R:R:N407	4.12	No	No	0	4	6
397	R:R:E412	R:R:K415	6.75	Yes	No	0	8	7
398	R:R:R421	R:R:W417	27.99	No	No	0	4	5
399	R:R:R421	R:R:W420	8	No	No	0	4	4
400	R:R:E423	R:R:W420	3.27	No	No	0	4	4
401	R:R:D59	R:R:L60	2.71	No	No	0	3	1
402	R:R:D215	R:R:L217	2.71	No	No	0	3	4
403	R:R:P73	R:R:W72	2.7	No	Yes	0	5	9
404	L:L:E21	R:R:L32	2.65	Yes	Yes	0	0	4
405	L:L:S18	R:R:R299	2.64	No	Yes	0	0	4
406	R:R:F390	R:R:S389	2.64	No	No	0	6	5
407	R:R:F393	R:R:S389	2.64	No	No	0	7	5
408	R:R:F413	R:R:V409	2.62	No	No	0	5	9
409	R:R:A239	R:R:W274	2.59	No	Yes	0	8	9
410	R:R:H173	R:R:L167	2.57	No	No	0	7	3
411	R:R:E364	R:R:E387	2.54	Yes	No	0	8	8
412	R:R:S261	R:R:W264	2.47	No	No	0	7	5
413	R:R:V36	R:R:W33	2.45	No	No	0	2	3
414	L:L:I29	R:R:Y88	2.42	No	Yes	1	0	5
415	R:R:N406	R:R:R176	2.41	No	Yes	0	9	9
416	R:R:I265	R:R:W264	2.35	No	No	0	5	5
417	R:R:L189	R:R:W274	2.28	No	Yes	0	7	9
418	R:R:L268	R:R:W264	2.28	No	No	0	2	5
419	R:R:H173	R:R:R170	2.26	No	No	0	7	8
420	R:R:E41	R:R:W87	2.18	No	Yes	0	4	3
421	R:R:E418	R:R:W417	2.18	No	No	0	4	5
422	R:R:R40	R:R:R43	2.13	No	Yes	0	2	4
423	R:R:F195	R:R:Y152	2.06	No	Yes	0	7	7
424	R:R:G275	R:R:P277	2.03	No	Yes	0	6	9
425	R:R:C62	R:R:G75	1.96	Yes	No	1	9	7
426	R:R:C62	R:R:G108	1.96	Yes	No	0	9	9
427	R:R:C104	R:R:G75	1.96	No	No	1	9	7
428	R:R:C85	R:R:G98	1.96	No	No	0	9	4
429	R:R:A158	R:R:A399	1.79	No	No	0	7	8
430	R:R:P137	R:R:S136	1.78	No	No	0	3	1
431	R:R:P90	R:R:V30	1.77	Yes	No	0	4	2
432	R:R:P96	R:R:V95	1.77	No	No	0	3	5
433	R:R:G108	R:R:L60	1.71	No	No	0	9	1
434	R:R:A208	R:R:S206	1.71	No	No	0	4	4
435	R:R:A209	R:R:S206	1.71	No	No	0	1	4
436	R:R:G361	R:R:L244	1.71	No	Yes	0	9	9
437	R:R:C329	R:R:V325	1.71	No	No	0	7	5
438	R:R:A350	R:R:T353	1.68	No	No	0	8	9
439	L:L:G35	R:R:E68	1.64	No	No	0	0	4
440	R:R:L60	R:R:P77	1.64	No	No	0	1	4
441	R:R:S223	R:R:S225	1.63	No	No	0	4	3
442	R:R:S129	R:R:V95	1.62	No	No	0	1	5
443	R:R:S193	R:R:V194	1.62	No	Yes	0	6	7
444	R:R:V327	R:R:V331	1.6	Yes	No	0	9	8
445	R:R:A92	R:R:L89	1.58	No	Yes	0	5	5
446	R:R:C174	R:R:N177	1.57	No	Yes	0	8	9
447	R:R:I286	R:R:V282	1.54	No	No	0	4	3
448	R:R:I328	R:R:V332	1.54	Yes	No	0	7	6
449	R:R:I400	R:R:V405	1.54	No	No	0	6	6
450	R:R:K336	R:R:V332	1.52	No	No	0	6	6
451	R:R:I382	R:R:T378	1.52	No	No	0	4	2
452	R:R:A106	R:R:E107	1.51	No	No	0	1	5
453	R:R:F369	R:R:G318	1.51	No	No	0	4	4
454	R:R:L278	R:R:V282	1.49	No	No	0	3	3
455	R:R:L354	R:R:T353	1.47	No	No	0	8	9
456	R:R:Q112	R:R:S116	1.44	No	No	0	3	5
457	R:R:E52	R:R:T51	1.41	No	No	0	2	4
458	R:R:D344	R:R:I345	1.4	No	No	0	7	5
459	R:R:A153	R:R:F195	1.39	No	No	0	6	7
460	R:R:L224	R:R:L228	1.38	No	No	0	3	4
461	R:R:A375	R:R:R380	1.38	No	Yes	0	4	5
462	R:R:E127	R:R:L123	1.33	No	Yes	0	2	5
463	R:R:F169	R:R:S416	1.32	Yes	No	0	7	5
464	R:R:R419	R:R:S416	1.32	No	No	0	7	5
465	R:R:D222	R:R:Q221	1.31	No	Yes	0	6	4
466	R:R:A185	R:R:W274	1.3	No	Yes	0	3	9
467	R:R:E138	R:R:E139	1.27	No	No	0	2	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:E9	7.475	4	2	0
2	L:L:F12	5.864	5	2	0
3	L:L:V16	3.776	5	2	0
4	L:L:E21	8.176	5	0	0
5	L:L:F28	9.316	5	1	0
6	R:R:L32	4.006	5	0	4
7	R:R:W39	6.956	5	1	5
8	R:R:Y42	6.126	5	1	6
9	R:R:R43	4.13	4	0	4
10	R:R:F61	10.8225	4	10	3
11	R:R:C62	6.2625	4	1	9
12	R:R:R64	12.2275	4	8	4
13	R:R:D67	6.3425	4	1	9
14	R:R:Y69	5.268	5	1	6
15	R:R:W72	8.32857	7	1	9
16	R:R:D74	7.362	5	8	3
17	R:R:W87	7.145	4	1	3
18	R:R:Y88	4.53	5	1	5
19	R:R:L89	5.345	4	1	5
20	R:R:P90	5.476	5	1	4
21	R:R:W91	11.065	4	1	4
22	R:R:V100	3.7675	4	1	7
23	R:R:R102	15.862	5	1	8
24	R:R:F103	15.1275	4	1	4
25	R:R:W110	14.605	4	1	9
26	R:R:W120	4.604	5	1	5
27	R:R:L123	5.3325	4	0	5
28	R:R:E125	5.262	5	1	5
29	R:R:Y145	12.256	5	2	5
30	R:R:Y148	6.88375	8	2	7
31	R:R:Y152	7.666	5	2	7
32	R:R:F156	4.75	4	12	7
33	R:R:L159	4.24	4	0	9
34	R:R:L166	5.036	5	4	8
35	R:R:F169	5.9275	4	4	7
36	R:R:L172	5.225	4	4	9
37	R:R:R176	3.4075	4	4	9
38	R:R:N177	3.6275	4	4	9
39	R:R:H180	5.255	4	4	9
40	R:R:F184	4.06833	6	4	8
41	R:R:F187	6.998	5	0	8
42	R:R:R190	8.06	5	0	8
43	R:R:V194	5.6175	4	2	7
44	R:R:K197	5.965	6	2	6
45	R:R:D198	6.4825	4	2	7
46	R:R:Y205	9.97	4	0	3
47	R:R:W214	11.975	6	1	1
48	R:R:Y220	5.3225	4	0	3
49	R:R:Q221	6.675	4	0	4
50	R:R:F230	4.982	5	2	5
51	R:R:Q234	7.5225	4	3	7
52	R:R:N240	8.485	4	0	9
53	R:R:Y241	10.0925	4	5	8
54	R:R:Y242	5.594	5	7	6
55	R:R:W243	9.81833	6	13	9
56	R:R:L244	3.1475	4	0	9
57	R:R:L245	3.785	4	7	8
58	R:R:Y250	7.69	4	0	8
59	R:R:Y269	4.28	5	0	7
60	R:R:W274	5.70833	6	13	9
61	R:R:P277	3.155	4	0	9
62	R:R:F280	7.1925	4	7	5
63	R:R:W284	8.618	5	3	8
64	R:R:K288	5.8425	4	3	8
65	R:R:E294	7.228	5	3	4
66	R:R:C296	5.6825	4	2	9
67	R:R:W297	6.754	5	3	8
68	R:R:R299	7.7925	4	0	4
69	R:R:W306	8.96	5	3	6
70	R:R:R310	9.975	4	3	6
71	R:R:I317	3.64	4	5	7
72	R:R:V327	3.0075	4	6	9
73	R:R:I328	3.8075	4	6	7
74	R:R:L356	4.3225	4	6	9
75	R:R:L360	4.015	4	0	9
76	R:R:H363	7.3575	4	5	8
77	R:R:E364	7.875	4	5	8
78	R:R:F367	6.65	4	0	7
79	R:R:R380	7.57	4	0	5
80	R:R:L388	6.0175	4	2	7
81	R:R:T391	5.4275	4	5	6
82	R:R:Q394	4.1275	4	5	9
83	R:R:C403	4.005	4	4	9
84	R:R:E412	7.895	4	4	8
85	W:W:?1	11.263	10	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:Y148	R:R:Y152	93.5539	5.96	Yes	Yes	2	7	7
2	R:R:R190	R:R:Y152	89.1891	11.32	Yes	Yes	0	8	7
3	R:R:E364	R:R:E387	12.7324	2.54	Yes	No	0	8	8
4	R:R:E387	R:R:K383	11.9399	10.8	No	No	0	8	7
5	L:L:F12	R:R:Y148	30.1923	8.25	Yes	Yes	2	0	7
6	L:L:F12	L:L:V16	30.5094	5.24	Yes	Yes	2	0	0
7	L:L:L20	L:L:V16	30.7247	2.98	No	Yes	2	0	0
8	R:R:Y145	R:R:Y148	30.5853	4.96	Yes	Yes	2	5	7
9	R:R:Y145	W:W:?1	30.5942	37.05	Yes	Yes	2	5	0
10	L:L:L20	W:W:?1	61.607	9.94	No	Yes	2	0	0
11	R:R:D198	R:R:Y148	30.426	9.2	Yes	Yes	2	7	7
12	R:R:D198	W:W:?1	30.9573	2.92	Yes	Yes	2	7	0
13	L:L:L20	R:R:Y205	92.2643	10.55	No	Yes	0	0	3
14	L:L:E21	R:R:Y205	94.6621	14.59	Yes	Yes	0	0	3
15	L:L:E21	R:R:L32	100	2.65	Yes	Yes	0	0	4
16	R:R:L32	R:R:W214	50.3675	6.83	Yes	Yes	0	4	1
17	L:L:I29	R:R:Y88	15.4449	2.42	No	Yes	1	0	5
18	L:L:L32	R:R:Y88	45.8848	3.52	No	Yes	1	0	5
19	L:L:F28	L:L:L32	46.278	10.96	Yes	No	1	0	0
20	L:L:F28	R:R:V36	48.6576	6.55	Yes	No	0	0	2
21	R:R:L32	R:R:V36	49.1239	2.98	Yes	No	0	4	2
22	R:R:W39	R:R:Y88	46.1155	5.79	Yes	Yes	1	5	5
23	L:L:F28	R:R:W39	50.8579	9.02	Yes	Yes	1	0	5
24	L:L:F28	R:R:W214	48.8052	17.04	Yes	Yes	1	0	1
25	R:R:Y69	R:R:Y88	68.1554	3.97	Yes	Yes	1	6	5
26	R:R:D67	R:R:Y69	30.4605	4.6	Yes	Yes	1	9	6
27	R:R:D67	R:R:R102	23.7731	3.57	Yes	Yes	1	9	8
28	R:R:R102	R:R:W110	18.0998	23.99	Yes	Yes	1	8	9
29	R:R:C62	R:R:W110	15.7248	15.67	Yes	Yes	1	9	9
30	R:R:C62	R:R:G108	13.988	1.96	Yes	No	0	9	9
31	R:R:G108	R:R:L60	13.117	1.71	No	No	0	9	1
32	R:R:L60	R:R:P77	11.3737	1.64	No	No	0	1	4
33	R:R:V100	R:R:Y69	32.8511	3.79	Yes	Yes	1	7	6
34	R:R:E125	R:R:V100	27.5184	2.85	Yes	Yes	1	5	7
35	R:R:E125	R:R:Y101	12.9139	12.35	Yes	No	0	5	5
36	R:R:F103	R:R:W120	12.065	6.01	Yes	Yes	1	4	5
37	R:R:D122	R:R:E125	10.3305	5.2	No	Yes	1	7	5
38	R:R:N240	R:R:R190	73.8482	10.85	Yes	Yes	0	9	8
39	R:R:F187	R:R:N240	37.44	14.5	Yes	Yes	0	8	9
40	R:R:F187	R:R:L159	17.3313	3.65	Yes	Yes	0	8	9
41	R:R:F184	R:R:L159	14.3641	7.31	Yes	Yes	0	8	9
42	R:R:F187	R:R:L183	20.324	7.31	Yes	No	0	8	9
43	R:R:E247	R:R:L183	39.7266	15.9	No	No	0	9	9
44	R:R:L244	R:R:N240	20.418	4.12	Yes	Yes	0	9	9
45	R:R:L183	R:R:L244	20.1744	2.77	No	Yes	0	9	9
46	R:R:N240	R:R:S186	17.4471	4.47	Yes	No	0	9	9
47	R:R:S186	R:R:W243	17.0617	4.94	No	Yes	0	9	9
48	R:R:E247	R:R:L359	31.68	9.28	No	No	0	9	9
49	R:R:W243	R:R:W274	11.5427	18.74	Yes	Yes	13	9	9
50	R:R:L359	R:R:L360	27.2378	5.54	No	Yes	0	9	9
51	R:R:L356	R:R:L360	17.1672	4.15	Yes	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E9	R:R:Y148	13.47	2	Yes	Yes	0	7	0	1
L:L:E9	R:R:V194	5.7	2	Yes	Yes	0	7	0	1
L:L:E9	R:R:K197	6.75	2	Yes	Yes	0	6	0	1
L:L:E9	R:R:L388	3.98	2	Yes	Yes	0	7	0	1
L:L:G10	R:R:W306	2.81	0	No	Yes	0	6	0	1
L:L:T11	R:R:D372	4.34	0	No	No	0	5	0	1
L:L:T11	R:R:L384	4.42	0	No	No	0	5	0	1
L:L:F12	R:R:L141	4.87	2	Yes	No	0	5	0	1
L:L:F12	R:R:L144	3.65	2	Yes	No	0	6	0	1
L:L:F12	R:R:Y148	8.25	2	Yes	Yes	0	7	0	1
L:L:F12	R:R:L388	7.31	2	Yes	Yes	0	7	0	1
L:L:T13	R:R:K197	10.51	2	No	Yes	0	6	0	1
L:L:T13	R:R:F230	3.89	2	No	Yes	0	5	0	1
L:L:S14	R:R:N300	8.94	0	No	No	0	6	0	1
L:L:D15	R:R:R380	10.72	0	No	Yes	0	5	0	1
L:L:V16	R:R:L141	4.47	2	Yes	No	0	5	0	1
L:L:V16	R:R:L201	2.98	2	Yes	No	0	7	0	1
L:L:V16	W:W:?1	3.21	2	Yes	Yes	0	0	0	1
L:L:S17	R:R:Y205	6.36	0	No	Yes	0	3	0	1
L:L:S17	R:R:T298	9.59	0	No	No	0	5	0	1
L:L:S17	R:R:R299	5.27	0	No	Yes	0	4	0	1
L:L:S18	R:R:T29	6.4	0	No	No	0	2	0	1
L:L:Y19	R:R:E138	7.86	0	No	No	0	2	0	1
L:L:Y19	W:W:?1	4.21	0	No	Yes	0	0	0	1
L:L:L20	R:R:Y205	10.55	2	No	Yes	0	3	0	1
L:L:L20	W:W:?1	9.94	2	No	Yes	0	0	0	1
L:L:E21	R:R:S31	5.75	0	Yes	No	0	4	0	1
L:L:E21	R:R:Y205	14.59	0	Yes	Yes	0	3	0	1
L:L:E21	R:R:Q221	5.1	0	Yes	Yes	0	4	0	1
L:L:E21	R:R:R299	12.79	0	Yes	Yes	0	4	0	1
L:L:A24	R:R:L32	3.15	0	No	Yes	0	4	0	1
L:L:A24	R:R:Q210	3.03	0	No	No	0	4	0	1
L:L:A25	R:R:P90	3.74	0	No	Yes	0	4	0	1
L:L:E27	R:R:Q210	6.37	1	No	No	0	4	0	1
L:L:E27	R:R:W214	3.27	1	No	Yes	0	1	0	1
L:L:F28	R:R:V36	6.55	1	Yes	No	0	2	0	1
L:L:F28	R:R:W39	9.02	1	Yes	Yes	0	5	0	1
L:L:F28	R:R:W214	17.04	1	Yes	Yes	0	1	0	1
L:L:I29	R:R:L89	2.85	1	No	Yes	0	5	0	1
L:L:I29	R:R:P90	5.08	1	No	Yes	0	4	0	1
L:L:W31	R:R:W214	20.62	1	No	Yes	0	1	0	1
L:L:L32	R:R:W39	7.97	1	No	Yes	0	5	0	1
L:L:L32	R:R:Y88	3.52	1	No	Yes	0	5	0	1
L:L:V33	R:R:L123	4.47	0	No	Yes	0	5	0	1
L:L:R36	R:R:W39	9	0	No	Yes	0	5	0	1
L:L:R36	R:R:E68	20.93	0	No	No	0	4	0	1
R:R:L32	R:R:T35	4.42	0	Yes	No	4	5	1	2
R:R:L32	R:R:V36	2.98	0	Yes	No	4	2	1	1
R:R:L32	R:R:W214	6.83	0	Yes	Yes	4	1	1	1
R:R:R43	R:R:W39	3	0	Yes	Yes	4	5	2	1
R:R:W39	R:R:Y88	5.79	1	Yes	Yes	5	5	1	1
R:R:Y42	R:R:Y88	6.95	1	Yes	Yes	6	5	2	1
R:R:Y69	R:R:Y88	3.97	1	Yes	Yes	6	5	2	1
R:R:L123	R:R:Y69	7.03	0	Yes	Yes	5	6	1	2
R:R:L89	R:R:P90	3.28	1	Yes	Yes	5	4	1	1
R:R:L89	R:R:W91	13.67	1	Yes	Yes	5	4	1	2
R:R:P90	R:R:W91	13.51	1	Yes	Yes	4	4	1	2
R:R:L123	R:R:R121	8.5	0	Yes	No	5	6	1	2
R:R:E138	R:R:S136	7.19	0	No	No	2	1	1	2
R:R:L141	W:W:?1	2.98	2	No	Yes	5	0	1	1
R:R:L142	W:W:?1	17.9	0	No	Yes	3	0	2	1
R:R:F381	R:R:L144	3.65	0	No	No	4	6	2	1
R:R:L144	R:R:L388	6.92	2	No	Yes	6	7	1	1
R:R:I146	R:R:Y145	3.63	2	No	Yes	4	5	2	2
R:R:Y145	R:R:Y148	4.96	2	Yes	Yes	5	7	2	1
R:R:D198	R:R:Y145	6.9	2	Yes	Yes	7	5	2	2
R:R:Y145	W:W:?1	37.05	2	Yes	Yes	5	0	2	1
R:R:I146	W:W:?1	3.08	2	No	Yes	4	0	2	1
R:R:Y148	R:R:Y152	5.96	2	Yes	Yes	7	7	1	2
R:R:V194	R:R:Y148	3.79	2	Yes	Yes	7	7	1	1
R:R:K197	R:R:Y148	3.58	2	Yes	Yes	6	7	1	1
R:R:D198	R:R:Y148	9.2	2	Yes	Yes	7	7	2	1
R:R:L388	R:R:Y148	5.86	2	Yes	Yes	7	7	1	1
R:R:V194	R:R:Y152	11.36	2	Yes	Yes	7	7	1	2
R:R:D198	R:R:K197	6.91	2	Yes	Yes	7	6	2	1
R:R:F230	R:R:K197	3.72	2	Yes	Yes	5	6	1	1
R:R:K197	R:R:M233	4.32	2	Yes	No	6	6	1	2
R:R:D198	W:W:?1	2.92	2	Yes	Yes	7	0	2	1
R:R:L201	W:W:?1	2.98	2	No	Yes	7	0	1	1
R:R:K202	W:W:?1	28.36	0	No	Yes	4	0	2	1
R:R:M204	R:R:Y205	8.38	2	No	Yes	3	3	2	1
R:R:C296	R:R:M204	6.48	2	Yes	No	9	3	2	2
R:R:Q210	R:R:W214	19.71	1	No	Yes	4	1	1	1
R:R:Q211	R:R:W214	4.38	0	No	Yes	4	1	2	1
R:R:Q213	R:R:Q221	15.36	0	No	Yes	4	4	2	1
R:R:G295	R:R:Q221	4.93	0	No	Yes	4	4	2	1
R:R:F230	R:R:V229	3.93	2	Yes	No	5	7	1	2
R:R:C296	R:R:F230	5.59	2	Yes	Yes	9	5	2	1
R:R:F230	R:R:T298	7.78	2	Yes	No	5	5	1	1
R:R:M233	R:R:Q234	6.8	0	No	Yes	6	7	2	2
R:R:Q234	R:R:W306	6.57	3	Yes	Yes	7	6	2	1
R:R:I309	R:R:Q234	6.86	3	No	Yes	7	7	2	2
R:R:E294	R:R:G295	3.27	3	Yes	No	4	4	2	2
R:R:E294	R:R:R299	10.47	3	Yes	Yes	4	4	2	1
R:R:C296	R:R:T298	3.38	2	Yes	No	9	5	2	1
R:R:N300	R:R:W306	13.56	0	No	Yes	6	6	1	1
R:R:I309	R:R:W306	5.87	3	No	Yes	7	6	2	1
R:R:R310	R:R:W306	15.99	3	Yes	Yes	6	6	2	1
R:R:D372	R:R:R380	10.72	0	No	Yes	5	5	1	1
R:R:R376	R:R:R380	7.46	0	No	Yes	5	5	2	1
R:R:K383	R:R:L384	2.82	0	No	No	7	5	2	1
L:L:E21	R:R:L32	2.65	0	Yes	Yes	0	4	0	1
L:L:S18	R:R:R299	2.64	0	No	Yes	0	4	0	1
R:R:V36	R:R:W33	2.45	0	No	No	2	3	1	2
L:L:I29	R:R:Y88	2.42	1	No	Yes	0	5	0	1
R:R:P90	R:R:V30	1.77	1	Yes	No	4	2	1	2
L:L:G35	R:R:E68	1.64	0	No	No	0	4	0	1
R:R:S193	R:R:V194	1.62	0	No	Yes	6	7	2	1
R:R:A92	R:R:L89	1.58	0	No	Yes	5	5	2	1
R:R:A375	R:R:R380	1.38	0	No	Yes	4	5	2	1
R:R:E127	R:R:L123	1.33	0	No	Yes	2	5	2	1
R:R:D222	R:R:Q221	1.31	0	No	Yes	6	4	2	1
R:R:E138	R:R:E139	1.27	0	No	No	2	2	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:F12	L:L:V16	5.24	2	Yes	Yes	0	0	2	1
L:L:F12	R:R:L141	4.87	2	Yes	No	0	5	2	1
L:L:F12	R:R:Y148	8.25	2	Yes	Yes	0	7	2	2
L:L:L20	L:L:V16	2.98	2	No	Yes	0	0	1	1
L:L:V16	R:R:L141	4.47	2	Yes	No	0	5	1	1
L:L:V16	R:R:L201	2.98	2	Yes	No	0	7	1	1
L:L:V16	W:W:?1	3.21	2	Yes	Yes	0	0	1	0
L:L:Q23	L:L:Y19	7.89	0	No	No	0	0	2	1
L:L:Y19	R:R:E138	7.86	0	No	No	0	2	1	2
L:L:Y19	W:W:?1	4.21	0	No	Yes	0	0	1	0
L:L:L20	R:R:Y205	10.55	2	No	Yes	0	3	1	2
L:L:L20	W:W:?1	9.94	2	No	Yes	0	0	1	0
R:R:L141	W:W:?1	2.98	2	No	Yes	5	0	1	0
R:R:L142	W:W:?1	17.9	0	No	Yes	3	0	1	0
R:R:I146	R:R:Y145	3.63	2	No	Yes	4	5	1	1
R:R:Y145	R:R:Y148	4.96	2	Yes	Yes	5	7	1	2
R:R:T149	R:R:Y145	8.74	0	No	Yes	7	5	2	1
R:R:D198	R:R:Y145	6.9	2	Yes	Yes	7	5	1	1
R:R:Y145	W:W:?1	37.05	2	Yes	Yes	5	0	1	0
R:R:I146	W:W:?1	3.08	2	No	Yes	4	0	1	0
R:R:K197	R:R:Y148	3.58	2	Yes	Yes	6	7	2	2
R:R:D198	R:R:Y148	9.2	2	Yes	Yes	7	7	1	2
R:R:D198	R:R:K197	6.91	2	Yes	Yes	7	6	1	2
R:R:D198	W:W:?1	2.92	2	Yes	Yes	7	0	1	0
R:R:L201	W:W:?1	2.98	2	No	Yes	7	0	1	0
R:R:K202	W:W:?1	28.36	0	No	Yes	4	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9IVM_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.77
Number of Linked Nodes	387
Number of Links	467
Number of Hubs	85
Number of Links mediated by Hubs	297
Number of Communities	13
Number of Nodes involved in Communities	115
Number of Links involved in Communities	161

Path Summary
Number Of Nodes in MetaPath	52
Number Of Links MetaPath	51
Number of Shortest Paths	554296
Length Of Smallest Path	3
Average Path Length	21.9569
Length of Longest Path	38
Minimum Path Strength	1.32
Average Path Strength	7.59696
Maximum Path Strength	32.705
Minimum Path Correlation	0.7
Average Path Correlation	0.954494
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	48.4821
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	67.7087
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • D2 dopamine receptor binding • adenylate cyclase inhibitor activity • molecular function inhibitor activity • cyclase inhibitor activity • enzyme inhibitor activity • magnesium ion binding • GDP binding • G protein-coupled serotonin receptor binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • cellular homeostasis • chemical homeostasis • homeostatic process • glucose homeostasis • carbohydrate homeostasis • intracellular chemical homeostasis • intracellular glucose homeostasis • system process • regulation of biological process • nervous system process • neuromuscular process • regulation of system process • biological regulation • skeletal muscle contraction • muscle contraction • muscle system process • regulation of muscle system process • striated muscle contraction • multicellular organismal movement • musculoskeletal movement • regulation of striated muscle contraction • regulation of muscle contraction • regulation of skeletal muscle contraction • regulation of multicellular organismal process • sensory perception of chemical stimulus • sensory perception • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • positive regulation of biological process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • positive regulation of cell communication • regulation of localization • establishment of protein localization • nitrogen compound transport • positive regulation of establishment of protein localization • localization • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • intracellular protein localization • regulation of peptide hormone secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular response to carbohydrate stimulus • response to glucose • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • peptide secretion • regulation of secretion by cell • secretion by cell • positive regulation of hormone secretion • response to monosaccharide • response to carbohydrate • positive regulation of secretion • signal release • cellular response to hexose stimulus • cellular response to monosaccharide stimulus • positive regulation of cellular process • positive regulation of peptide secretion • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • cellular response to glucose stimulus • regulation of protein transport • positive regulation of protein secretion • peptide transport • response to hexose • positive regulation of transport • regulation of cellular localization • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • regulation of insulin secretion involved in cellular response to glucose stimulus • hormone transport • regulation of cell communication • insulin secretion • positive regulation of signaling • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • cellular response to catecholamine stimulus • serotonin receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-activating serotonin receptor signaling pathway • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • adenylate cyclase-activating dopamine receptor signaling pathway • G protein-coupled dopamine receptor signaling pathway • cell surface receptor signaling pathway • bile acid signaling pathway • adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway • renal system process • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • cell division • leukocyte migration • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • relaxation of smooth muscle • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • negative regulation of transport • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • negative regulation of peptide hormone secretion • negative regulation of establishment of protein localization • negative regulation of protein secretion • negative regulation of signaling • negative regulation of cell communication • negative regulation of peptide secretion • negative regulation of cellular process • negative regulation of protein localization • negative regulation of insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • protein localization to cell cortex • cellular response to forskolin • response to forskolin • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cell projection • sperm principal piece • cilium • 9+2 motile cilium • sperm flagellum • motile cilium • plasma membrane bounded cell projection • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • ciliary basal body • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • glucagon receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • peptide hormone binding • hormone binding • glucagon-like peptide 1 receptor activity • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • heart process • regulation of heart contraction • regulation of system process • circulatory system process • regulation of blood circulation • regulation of multicellular organismal process • heart contraction • blood circulation • regulation of blood pressure • positive regulation of blood pressure • response to stress • response to psychosocial stress • cell surface receptor signaling pathway • behavior • learning or memory • cognition • transport • secretion • regulation of hormone levels • export from cell • hormone secretion • establishment of localization • localization • secretion by cell • signal release • hormone transport • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • establishment of protein localization • cellular localization • protein targeting • protein transmembrane transport • establishment of localization in cell • post-translational protein targeting to membrane, translocation • intracellular protein localization • establishment of protein localization to endoplasmic reticulum • establishment of protein localization to membrane • intracellular protein transmembrane transport • intracellular transport • post-translational protein targeting to endoplasmic reticulum membrane • localization within membrane • protein targeting to membrane • transmembrane transport • establishment of protein localization to organelle • protein transport • macromolecule localization • intracellular protein transport • protein targeting to ER • negative regulation of blood pressure
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like • FnI-like domain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like • FnI-like domain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_W_
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	_W_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>9IVM_nogp_Chain_R T V S L W E T V Q K W R E Y R R Q C Q R S L T E D P P P A T D L F C N R T F D E Y A C W P D G E P G S F V N V S C P W Y L P W A S S V P Q G H V Y R F C T A E G L W L Q K D N S S L P W R D L S E C E E S S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L S C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S V L S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F V R V I C I V V S K L K A N D I K C R L A K S T L T L I P L L G T H E V I F A F V M D E H A R G T L R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	doi.org/10.1038/nature22378
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	doi.org/10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	doi.org/10.1038/nature22394
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	doi.org/10.1038/nature22378
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	doi.org/10.1038/nature22800
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	doi.org/10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	doi.org/10.1038/nature25773
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.1	2019-11-13	doi.org/10.1107/S2052252519013496
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.2	2020-03-18	doi.org/10.1038/s41467-020-14934-5
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4-D-Ala	-		2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide (non-acylated)	-	Gs/β1/γ2	3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide (non-acylated)	-		3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	doi.org/10.1021/acs.jmedchem.1c01856
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	9EBN	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBN (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-	Gs/β1/γ2	3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-		3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	8YWF	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ2	2.74	2025-04-16	To be published
	8YWF (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.74	2025-04-16	To be published
	9BYO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-	Gs/β1/γ2	2.31	2025-06-11	To be published
	9BYO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-		2.31	2025-06-11	To be published
	9C0K	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	2.72	2025-06-11	To be published
	9C0K (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		2.72	2025-06-11	To be published
	9E2A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	3.3	2025-10-29	To be published
	9E2A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		3.3	2025-10-29	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9IVM_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.