psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E9	R:R:Y148	3.37	No	Yes	0	0	7
2	L:L:E9	R:R:K197	2.7	No	No	0	0	6
3	L:L:D15	L:L:T11	4.34	No	Yes	0	0	0
4	L:L:T11	R:R:L141	16.21	Yes	No	0	0	5
5	L:L:T11	R:R:Y145	3.75	Yes	Yes	0	0	5
6	L:L:F12	L:L:V16	3.93	Yes	No	7	0	0
7	L:L:F12	R:R:Y145	7.22	Yes	Yes	7	0	5
8	L:L:F12	R:R:D198	5.97	Yes	No	7	0	7
9	L:L:F12	R:R:L201	3.65	Yes	No	7	0	7
10	L:L:F12	R:R:K202	9.93	Yes	No	0	0	4
11	L:L:T13	R:R:S31	9.59	No	No	0	0	4
12	L:L:L20	L:L:V16	2.98	No	No	0	0	0
13	L:L:V16	R:R:L201	2.98	No	No	7	0	7
14	L:L:S17	R:R:L32	7.51	No	Yes	10	0	4
15	L:L:S17	R:R:T35	6.4	No	No	10	0	5
16	L:L:Y19	R:R:Y205	5.96	No	No	0	0	3
17	L:L:L20	R:R:L32	4.15	No	Yes	0	0	4
18	L:L:E21	R:R:L89	13.25	Yes	No	2	0	5
19	L:L:E21	R:R:P90	7.86	Yes	No	0	0	4
20	L:L:E21	R:R:W91	5.45	Yes	Yes	2	0	4
21	L:L:E27	L:L:Q23	3.82	No	No	11	0	0
22	L:L:Q23	R:R:Q211	6.4	No	No	11	0	4
23	L:L:Q23	R:R:W214	8.76	No	No	0	0	1
24	L:L:A25	R:R:Y69	2.67	No	Yes	0	0	6
25	L:L:E27	L:L:F28	3.5	No	No	0	0	0
26	L:L:E27	R:R:Q211	19.11	No	No	11	0	4
27	L:L:F28	R:R:E68	7	No	No	0	0	4
28	L:L:F28	R:R:W214	5.01	No	No	0	0	1
29	L:L:I29	R:R:L118	5.71	No	No	0	0	4
30	R:R:S31	R:R:W33	4.94	No	Yes	8	4	3
31	R:R:E34	R:R:S31	5.75	Yes	No	8	4	4
32	R:R:L32	R:R:T35	2.95	Yes	No	10	4	5
33	R:R:L32	R:R:V36	2.98	Yes	No	0	4	2
34	R:R:E34	R:R:W33	3.27	Yes	Yes	8	4	3
35	R:R:W33	R:R:Y220	12.54	Yes	No	0	3	3
36	R:R:T298	R:R:W33	12.13	No	Yes	8	5	3
37	R:R:E34	R:R:T298	8.47	Yes	No	8	4	5
38	R:R:E34	R:R:R299	4.65	Yes	No	0	4	4
39	R:R:P90	R:R:T35	8.74	No	No	0	4	5
40	R:R:R40	R:R:V36	2.62	No	No	0	2	2
41	R:R:V36	R:R:Y220	12.62	No	No	0	2	3
42	R:R:Q37	R:R:R40	5.84	No	No	0	4	2
43	R:R:Q37	R:R:Y220	4.51	No	No	0	4	3
44	R:R:E294	R:R:Q37	6.37	No	No	0	4	4
45	R:R:R43	R:R:W39	8	Yes	No	0	4	5
46	R:R:W39	R:R:Y88	10.61	No	Yes	0	5	5
47	R:R:E41	R:R:Q45	6.37	No	No	0	4	5
48	R:R:E41	R:R:W87	3.27	No	No	0	4	3
49	R:R:R43	R:R:Y42	10.29	Yes	Yes	2	4	6
50	R:R:C46	R:R:Y42	8.06	Yes	Yes	2	8	6
51	R:R:C71	R:R:Y42	2.69	Yes	Yes	2	9	6
52	R:R:W87	R:R:Y42	8.68	No	Yes	0	3	6
53	R:R:Y42	R:R:Y88	13.9	Yes	Yes	2	6	5
54	R:R:C46	R:R:R43	9.75	Yes	Yes	2	8	4
55	R:R:Q47	R:R:R43	9.35	No	Yes	2	3	4
56	R:R:F66	R:R:R43	18.17	No	Yes	2	7	4
57	R:R:C71	R:R:R43	5.57	Yes	Yes	2	9	4
58	R:R:Q45	R:R:R44	3.5	No	No	0	5	3
59	R:R:Q47	R:R:R44	3.5	No	No	0	3	3
60	R:R:Q45	R:R:R48	4.67	No	No	0	5	4
61	R:R:C46	R:R:S49	3.44	Yes	No	0	8	2
62	R:R:C46	R:R:C71	5.46	Yes	Yes	2	8	9
63	R:R:F66	R:R:Q47	15.23	No	No	2	7	3
64	R:R:E52	R:R:R48	16.28	No	No	0	2	4
65	R:R:E52	R:R:S49	2.87	No	No	0	2	2
66	R:R:L50	R:R:R64	9.72	No	No	0	4	4
67	R:R:C71	R:R:L50	3.17	Yes	No	0	9	4
68	R:R:D53	R:R:P54	4.83	No	No	0	3	2
69	R:R:D53	R:R:R64	3.57	No	No	0	3	4
70	R:R:P56	R:R:T58	3.5	No	No	0	1	1
71	R:R:D74	R:R:P56	4.83	Yes	No	0	3	1
72	R:R:F61	R:R:T58	6.49	No	No	0	3	1
73	R:R:D59	R:R:L60	16.29	No	No	0	3	1
74	R:R:D74	R:R:F61	14.33	Yes	No	0	3	3
75	R:R:C104	R:R:C62	7.28	No	No	0	9	9
76	R:R:C62	R:R:W110	6.53	No	No	0	9	9
77	R:R:P73	R:R:R64	4.32	No	No	0	5	4
78	R:R:T65	R:R:W72	4.85	No	Yes	0	5	9
79	R:R:D67	R:R:W72	4.47	No	Yes	0	9	9
80	R:R:P86	R:R:Y69	13.91	Yes	Yes	2	8	6
81	R:R:Y69	R:R:Y88	3.97	Yes	Yes	2	6	5
82	R:R:C126	R:R:Y69	2.69	Yes	Yes	2	9	6
83	R:R:E127	R:R:Y69	3.37	No	Yes	0	2	6
84	R:R:R102	R:R:W72	24.99	Yes	Yes	4	8	9
85	R:R:P119	R:R:W72	5.4	Yes	Yes	4	6	9
86	R:R:L123	R:R:W72	9.11	No	Yes	4	5	9
87	R:R:D74	R:R:G75	5.03	Yes	No	0	3	7
88	R:R:E76	R:R:S79	4.31	No	No	0	1	5
89	R:R:F103	R:R:F80	3.22	Yes	No	0	4	4
90	R:R:H99	R:R:N82	16.58	Yes	No	0	4	4
91	R:R:H99	R:R:S84	6.97	Yes	No	0	4	4
92	R:R:C126	R:R:C85	7.28	Yes	No	2	9	9
93	R:R:P86	R:R:Y88	6.95	Yes	Yes	2	8	5
94	R:R:C126	R:R:P86	3.77	Yes	Yes	2	9	8
95	R:R:L89	R:R:Y88	10.55	No	Yes	2	5	5
96	R:R:L89	R:R:W91	7.97	No	Yes	2	5	4
97	R:R:E127	R:R:W91	3.27	No	Yes	0	2	4
98	R:R:K130	R:R:W91	4.64	No	Yes	0	1	4
99	R:R:K130	R:R:S94	6.12	No	No	0	1	4
100	R:R:P96	R:R:V95	3.53	No	No	0	3	5
101	R:R:E128	R:R:V95	5.7	No	No	0	3	5
102	R:R:E125	R:R:V100	7.13	No	Yes	0	5	7
103	R:R:R102	R:R:W110	10	Yes	No	4	8	9
104	R:R:R102	R:R:W120	4	Yes	Yes	4	8	5
105	R:R:D122	R:R:R102	13.1	No	Yes	4	7	8
106	R:R:F103	R:R:W120	9.02	Yes	Yes	4	4	5
107	R:R:F103	R:R:R121	7.48	Yes	No	4	4	6
108	R:R:E107	R:R:T105	15.52	No	No	0	5	4
109	R:R:E107	R:R:L109	5.3	No	No	0	5	5
110	R:R:W110	R:R:W120	8.43	No	Yes	4	9	5
111	R:R:L111	R:R:W120	19.36	No	Yes	0	4	5
112	R:R:N115	R:R:Q112	3.96	No	No	0	4	3
113	R:R:K113	R:R:L118	2.82	No	No	0	4	4
114	R:R:L118	R:R:P119	8.21	No	Yes	0	4	6
115	R:R:P119	R:R:W120	2.7	Yes	Yes	4	6	5
116	R:R:L123	R:R:P119	3.28	No	Yes	4	5	6
117	R:R:R121	R:R:W120	8	No	Yes	4	6	5
118	R:R:D122	R:R:W120	5.58	No	Yes	4	7	5
119	R:R:D122	R:R:R121	11.91	No	No	4	7	6
120	R:R:P137	R:R:S136	3.56	No	No	0	3	1
121	R:R:E139	R:R:F143	5.83	No	No	0	2	4
122	R:R:Q140	R:R:R380	3.5	No	Yes	0	4	5
123	R:R:F143	R:R:I147	3.77	No	No	0	4	6
124	R:R:L144	R:R:L384	4.15	No	Yes	3	6	5
125	R:R:L144	R:R:L388	4.15	No	No	3	6	7
126	R:R:I146	R:R:Y145	3.63	No	Yes	0	4	5
127	R:R:T149	R:R:Y145	8.74	No	Yes	0	7	5
128	R:R:D198	R:R:Y145	4.6	No	Yes	7	7	5
129	R:R:I147	R:R:S389	3.1	No	No	0	6	5
130	R:R:Y148	R:R:Y152	15.89	Yes	Yes	3	7	7
131	R:R:V194	R:R:Y148	3.79	No	Yes	3	7	7
132	R:R:L388	R:R:Y148	7.03	No	Yes	3	7	7
133	R:R:S392	R:R:Y148	6.36	No	Yes	3	9	7
134	R:R:G151	R:R:S392	3.71	No	No	0	8	9
135	R:R:F393	R:R:G151	9.03	No	No	0	7	8
136	R:R:R190	R:R:Y152	4.12	Yes	Yes	0	8	7
137	R:R:A191	R:R:Y152	4	No	Yes	0	7	7
138	R:R:V194	R:R:Y152	5.05	No	Yes	3	7	7
139	R:R:F195	R:R:Y152	3.09	No	Yes	0	7	7
140	R:R:S392	R:R:Y152	8.9	No	Yes	3	9	7
141	R:R:A153	R:R:F195	2.77	No	No	0	6	7
142	R:R:L159	R:R:S155	3	Yes	No	1	9	9
143	R:R:G395	R:R:S155	3.71	No	No	1	9	9
144	R:R:F156	R:R:V160	3.93	Yes	No	1	7	3
145	R:R:F156	R:R:I188	6.28	Yes	No	1	7	7
146	R:R:A191	R:R:F156	2.77	No	Yes	0	7	7
147	R:R:F156	R:R:L192	3.65	Yes	No	0	7	3
148	R:R:F184	R:R:L159	4.87	Yes	Yes	1	8	9
149	R:R:F187	R:R:L159	3.65	Yes	Yes	1	8	9
150	R:R:I188	R:R:L159	4.28	No	Yes	1	7	9
151	R:R:G395	R:R:L159	5.13	No	Yes	1	9	9
152	R:R:A399	R:R:L159	3.15	No	Yes	0	8	9
153	R:R:I188	R:R:V160	3.07	No	No	1	7	3
154	R:R:I161	R:R:I165	2.94	No	No	0	4	8
155	R:R:F404	R:R:I161	3.77	No	No	0	8	4
156	R:R:A162	R:R:F184	4.16	No	Yes	1	9	8
157	R:R:A162	R:R:C403	3.61	No	Yes	1	9	9
158	R:R:L181	R:R:S163	3	No	No	0	6	6
159	R:R:F184	R:R:S163	3.96	Yes	No	0	8	6
160	R:R:C403	R:R:I165	3.27	Yes	No	0	9	8
161	R:R:F413	R:R:I165	7.54	No	No	0	5	8
162	R:R:L166	R:R:N177	4.12	Yes	Yes	1	8	9
163	R:R:L166	R:R:L181	6.92	Yes	No	0	8	6
164	R:R:F184	R:R:L166	4.87	Yes	Yes	1	8	8
165	R:R:C403	R:R:L166	4.76	Yes	Yes	1	9	8
166	R:R:L167	R:R:L181	5.54	No	No	0	3	6
167	R:R:F169	R:R:L172	3.65	Yes	Yes	1	7	9
168	R:R:E412	R:R:F169	8.16	Yes	Yes	1	8	7
169	R:R:F169	R:R:F413	7.5	Yes	No	0	7	5
170	R:R:E412	R:R:H171	13.54	Yes	No	0	8	7
171	R:R:L172	R:R:N177	2.75	Yes	Yes	1	9	9
172	R:R:L172	R:R:V409	4.47	Yes	No	0	9	9
173	R:R:E412	R:R:L172	3.98	Yes	Yes	1	8	9
174	R:R:H173	R:R:Y178	8.71	No	No	0	7	6
175	R:R:C174	R:R:R176	4.18	No	Yes	1	8	9
176	R:R:C174	R:R:N177	4.72	No	Yes	1	8	9
177	R:R:I179	R:R:T175	3.04	Yes	No	1	8	7
178	R:R:T175	R:R:Y250	4.99	No	Yes	1	7	8
179	R:R:N177	R:R:R176	3.62	Yes	Yes	1	9	9
180	R:R:H180	R:R:R176	5.64	No	Yes	0	9	9
181	R:R:R176	R:R:Y250	3.09	Yes	Yes	1	9	8
182	R:R:E408	R:R:R176	5.82	No	Yes	0	9	9
183	R:R:F266	R:R:Y178	6.19	No	No	0	6	6
184	R:R:I179	R:R:V246	3.07	Yes	Yes	0	8	8
185	R:R:E247	R:R:I179	6.83	Yes	Yes	0	9	8
186	R:R:I179	R:R:Y250	6.04	Yes	Yes	1	8	8
187	R:R:E247	R:R:H180	11.08	Yes	No	0	9	9
188	R:R:H180	R:R:Y402	5.44	No	Yes	0	9	8
189	R:R:N182	R:R:W243	15.82	No	Yes	9	9	9
190	R:R:N182	R:R:W274	5.65	No	Yes	9	9	9
191	R:R:F187	R:R:L183	6.09	Yes	No	0	8	9
192	R:R:L183	R:R:L244	4.15	No	No	0	9	9
193	R:R:E247	R:R:L183	3.98	Yes	No	0	9	9
194	R:R:F184	R:R:V398	3.93	Yes	No	0	8	9
195	R:R:C403	R:R:F184	2.79	Yes	Yes	1	9	8
196	R:R:N240	R:R:S186	5.96	No	No	0	9	9
197	R:R:S186	R:R:W243	7.41	No	Yes	9	9	9
198	R:R:S186	R:R:W274	4.94	No	Yes	9	9	9
199	R:R:F187	R:R:N240	16.92	Yes	No	0	8	9
200	R:R:F187	R:R:Q394	12.88	Yes	Yes	1	8	9
201	R:R:F187	R:R:G395	6.02	Yes	No	1	8	9
202	R:R:R190	R:R:V237	7.85	Yes	No	0	8	6
203	R:R:N240	R:R:R190	9.64	No	Yes	0	9	8
204	R:R:R190	R:R:Y241	8.23	Yes	Yes	0	8	8
205	R:R:M233	R:R:S193	7.67	No	No	0	6	6
206	R:R:C236	R:R:S193	5.16	No	No	0	5	6
207	R:R:K202	R:R:Y205	7.17	No	No	0	4	3
208	R:R:T207	R:R:W203	3.64	No	No	0	3	3
209	R:R:M204	R:R:T207	3.01	No	No	0	3	3
210	R:R:G216	R:R:M204	3.49	No	No	0	2	3
211	R:R:Q210	R:R:Q213	10.24	No	No	0	4	4
212	R:R:H212	R:R:Q213	6.18	No	No	0	3	4
213	R:R:S219	R:R:S225	6.52	No	No	0	5	3
214	R:R:Q221	R:R:S223	8.66	No	No	0	4	4
215	R:R:D222	R:R:R227	4.76	Yes	No	6	6	8
216	R:R:D222	R:R:D293	5.32	Yes	No	0	6	7
217	R:R:C296	R:R:D222	3.11	Yes	Yes	0	9	6
218	R:R:D222	R:R:W297	6.7	Yes	Yes	6	6	8
219	R:R:L224	R:R:S223	4.5	No	No	0	3	4
220	R:R:C226	R:R:C296	7.28	No	Yes	0	9	9
221	R:R:L228	R:R:R227	7.29	No	No	0	4	8
222	R:R:R227	R:R:W297	5	No	Yes	6	8	8
223	R:R:L228	R:R:V229	2.98	No	No	0	4	7
224	R:R:F230	R:R:Q234	7.03	No	No	0	5	7
225	R:R:F230	R:R:W284	5.01	No	Yes	0	5	8
226	R:R:L231	R:R:V281	2.98	No	No	0	5	6
227	R:R:G285	R:R:L231	3.42	No	No	0	5	5
228	R:R:M233	R:R:Q234	2.72	No	No	0	6	7
229	R:R:W274	R:R:Y235	6.75	Yes	No	0	9	9
230	R:R:P277	R:R:Y235	8.34	No	No	0	9	9
231	R:R:L278	R:R:Y235	7.03	No	No	0	3	9
232	R:R:A238	R:R:F280	2.77	No	Yes	0	6	5
233	R:R:I313	R:R:Y241	8.46	No	Yes	1	7	8
234	R:R:I317	R:R:Y241	4.84	Yes	Yes	1	7	8
235	R:R:E364	R:R:Y241	12.35	Yes	Yes	1	8	8
236	R:R:V276	R:R:Y242	7.57	No	No	0	3	6
237	R:R:F280	R:R:Y242	7.22	Yes	No	0	5	6
238	R:R:A316	R:R:Y242	9.34	No	No	0	7	6
239	R:R:V246	R:R:W243	8.58	Yes	Yes	0	8	9
240	R:R:G273	R:R:W243	7.04	No	Yes	0	9	9
241	R:R:W243	R:R:W274	24.37	Yes	Yes	9	9	9
242	R:R:L244	R:R:Q394	5.32	No	Yes	0	9	9
243	R:R:L245	R:R:V249	2.98	No	No	0	8	6
244	R:R:L245	R:R:V319	4.47	No	No	0	8	6
245	R:R:L245	R:R:N320	4.12	No	No	0	8	9
246	R:R:V246	R:R:Y269	3.79	Yes	Yes	0	8	7
247	R:R:I272	R:R:V246	3.07	Yes	Yes	0	6	8
248	R:R:E247	R:R:L359	9.28	Yes	Yes	0	9	9
249	R:R:V249	R:R:Y269	3.79	No	Yes	0	6	7
250	R:R:L254	R:R:Y250	15.24	No	Yes	0	8	8
251	R:R:Y250	R:R:Y269	9.93	Yes	Yes	0	8	7
252	R:R:L251	R:R:L255	5.54	No	No	5	9	8
253	R:R:L251	R:R:V327	4.47	No	Yes	5	9	9
254	R:R:A256	R:R:Y252	4	No	No	0	6	8
255	R:R:I323	R:R:Y252	4.84	No	No	0	8	8
256	R:R:R326	R:R:Y252	4.12	No	No	0	8	8
257	R:R:F257	R:R:T253	3.89	No	No	0	5	7
258	R:R:T253	R:R:Y269	4.99	No	Yes	0	7	7
259	R:R:L255	R:R:V327	4.47	No	Yes	5	8	9
260	R:R:I330	R:R:L255	4.28	No	No	0	9	8
261	R:R:I265	R:R:L260	4.28	No	No	0	5	7
262	R:R:Q263	R:R:S261	5.78	No	No	0	5	7
263	R:R:E262	R:R:Q263	15.29	No	No	0	6	5
264	R:R:I265	R:R:Y269	8.46	No	Yes	0	5	7
265	R:R:F266	R:R:V270	7.87	No	No	0	6	5
266	R:R:I272	R:R:V276	3.07	Yes	No	0	6	3
267	R:R:P277	R:R:V276	3.53	No	No	0	9	3
268	R:R:F280	R:R:V281	2.62	Yes	No	0	5	6
269	R:R:F280	R:R:P312	17.34	Yes	No	0	5	8
270	R:R:P283	R:R:V282	3.53	No	No	0	5	3
271	R:R:K288	R:R:W284	5.8	Yes	Yes	6	8	8
272	R:R:W284	R:R:W297	4.69	Yes	Yes	6	8	8
273	R:R:W284	R:R:W306	2.81	Yes	Yes	6	8	6
274	R:R:I308	R:R:W284	7.05	No	Yes	0	8	8
275	R:R:I309	R:R:W284	7.05	No	Yes	6	7	8
276	R:R:G285	R:R:W297	2.81	No	Yes	0	5	8
277	R:R:I286	R:R:V287	3.07	No	No	0	4	4
278	R:R:V287	R:R:Y305	5.05	No	No	0	4	4
279	R:R:E292	R:R:K288	8.1	No	Yes	0	6	8
280	R:R:K288	R:R:W297	16.24	Yes	Yes	6	8	8
281	R:R:K288	R:R:N300	4.2	Yes	No	0	8	6
282	R:R:L290	R:R:Y289	4.69	No	No	0	3	3
283	R:R:W297	R:R:Y289	3.86	Yes	No	0	8	3
284	R:R:Y291	R:R:Y305	8.94	No	No	0	3	4
285	R:R:E292	R:R:S301	8.62	No	No	0	6	3
286	R:R:C296	R:R:T298	3.38	Yes	No	0	9	5
287	R:R:N300	R:R:W306	5.65	No	Yes	0	6	6
288	R:R:N302	R:R:N304	5.45	No	No	0	5	3
289	R:R:N302	R:R:Y305	10.47	No	No	0	5	4
290	R:R:L307	R:R:N304	2.75	No	No	0	7	3
291	R:R:I309	R:R:W306	3.52	No	Yes	6	7	6
292	R:R:R310	R:R:W306	8	No	Yes	0	6	6
293	R:R:L307	R:R:L311	4.15	No	No	0	7	4
294	R:R:I313	R:R:I317	2.94	No	Yes	1	7	7
295	R:R:F315	R:R:V319	7.87	No	No	0	4	6
296	R:R:E364	R:R:I317	2.73	Yes	Yes	1	8	7
297	R:R:L360	R:R:N320	5.49	Yes	No	0	9	9
298	R:R:F321	R:R:V325	2.62	No	No	0	6	5
299	R:R:F321	R:R:V365	14.42	No	No	0	6	6
300	R:R:F324	R:R:T353	5.19	Yes	No	0	9	9
301	R:R:F324	R:R:L356	7.31	Yes	Yes	5	9	9
302	R:R:F324	R:R:I357	5.02	Yes	No	5	9	8
303	R:R:F324	R:R:L360	3.65	Yes	Yes	5	9	9
304	R:R:F324	R:R:T362	15.56	Yes	No	5	9	7
305	R:R:I330	R:R:R326	6.26	No	No	0	9	8
306	R:R:L356	R:R:V327	2.98	Yes	Yes	5	9	9
307	R:R:I328	R:R:T353	3.04	No	No	0	7	9
308	R:R:S352	R:R:V331	3.23	No	No	0	9	8
309	R:R:L349	R:R:V332	4.47	No	No	0	9	6
310	R:R:K342	R:R:T343	3	No	No	0	5	5
311	R:R:C347	R:R:T343	3.38	No	No	0	7	5
312	R:R:K351	R:R:R348	12.38	No	No	0	8	8
313	R:R:L356	R:R:L359	2.77	Yes	Yes	5	9	9
314	R:R:L356	R:R:L360	8.3	Yes	Yes	5	9	9
315	R:R:I357	R:R:P358	3.39	No	No	0	8	9
316	R:R:I357	R:R:T362	4.56	No	No	5	8	7
317	R:R:M397	R:R:P358	3.35	No	No	0	5	9
318	R:R:L401	R:R:P358	4.93	No	No	0	8	9
319	R:R:L359	R:R:L360	4.15	Yes	Yes	5	9	9
320	R:R:L359	R:R:Y402	19.93	Yes	Yes	0	9	8
321	R:R:G361	R:R:H363	3.18	No	No	1	9	8
322	R:R:G361	R:R:Q394	3.29	No	Yes	1	9	9
323	R:R:E364	R:R:H363	8.62	Yes	No	1	8	8
324	R:R:H363	R:R:Q394	8.65	No	Yes	1	8	9
325	R:R:E364	R:R:T391	2.82	Yes	No	0	8	6
326	R:R:F367	R:R:I366	5.02	Yes	No	0	7	6
327	R:R:F367	R:R:T386	5.19	Yes	No	0	7	4
328	R:R:E387	R:R:F367	17.49	No	Yes	0	8	7
329	R:R:F367	R:R:F390	5.36	Yes	No	0	7	6
330	R:R:A375	R:R:H374	7.32	No	No	3	4	3
331	R:R:H374	R:R:K383	10.48	No	Yes	3	3	7
332	R:R:A375	R:R:R380	4.15	No	Yes	0	4	5
333	R:R:A375	R:R:K383	4.82	No	Yes	3	4	7
334	R:R:G377	R:R:R376	4.5	No	No	0	4	5
335	R:R:R376	R:R:R380	4.26	No	Yes	0	5	5
336	R:R:L384	R:R:R380	8.5	Yes	Yes	0	5	5
337	R:R:F381	R:R:I382	3.77	No	No	0	4	4
338	R:R:I382	R:R:T386	3.04	No	No	0	4	4
339	R:R:K383	R:R:L384	2.82	Yes	Yes	3	7	5
340	R:R:E387	R:R:K383	4.05	No	Yes	0	8	7
341	R:R:L384	R:R:L388	2.77	Yes	No	3	5	7
342	R:R:F385	R:R:T386	3.89	No	No	0	6	4
343	R:R:F393	R:R:S389	2.64	No	No	0	7	5
344	R:R:I400	R:R:L396	5.71	No	No	0	6	7
345	R:R:F404	R:R:I400	3.77	No	No	0	8	6
346	R:R:L401	R:R:Y402	3.52	No	Yes	0	8	8
347	R:R:E408	R:R:N406	9.2	No	No	0	9	9
348	R:R:N406	R:R:V409	7.39	No	No	0	9	9
349	R:R:E412	R:R:K415	8.1	Yes	No	0	8	7
350	R:R:R414	R:R:W417	11	No	No	0	6	5
351	R:R:K415	R:R:R419	7.43	No	No	0	7	7
352	R:R:R421	R:R:W417	8	No	No	0	4	5
353	R:R:E423	R:R:W420	3.27	No	No	0	4	4
354	R:R:D215	R:R:Q213	2.61	No	No	0	3	4
355	R:R:F103	R:R:T105	2.59	Yes	No	0	4	4
356	R:R:A239	R:R:W274	2.59	No	Yes	0	8	9
357	R:R:F321	R:R:T362	2.59	No	No	0	6	7
358	R:R:F266	R:R:I179	2.51	No	Yes	0	6	8
359	R:R:T355	R:R:Y402	2.5	No	Yes	0	8	8
360	R:R:H99	R:R:Q97	2.47	Yes	No	0	4	4
361	R:R:S206	R:R:W203	2.47	No	No	0	4	3
362	R:R:S261	R:R:W264	2.47	No	No	0	7	5
363	R:R:L335	R:R:R348	2.43	No	No	0	8	8
364	R:R:F61	R:R:N63	2.42	No	No	0	3	4
365	R:R:L290	R:R:Y291	2.34	No	No	0	3	3
366	R:R:E68	R:R:F66	2.33	No	No	0	4	7
367	R:R:L189	R:R:W274	2.28	No	Yes	0	7	9
368	R:R:H173	R:R:R170	2.26	No	No	0	7	8
369	R:R:G275	R:R:P277	2.03	No	No	0	6	9
370	R:R:C85	R:R:G98	1.96	No	No	0	9	4
371	R:R:C296	R:R:G295	1.96	Yes	No	0	9	4
372	R:R:P54	R:R:P55	1.95	No	No	0	2	1
373	R:R:P55	R:R:P56	1.95	No	No	0	1	1
374	R:R:A70	R:R:P86	1.87	No	Yes	0	5	8
375	R:R:G78	R:R:S79	1.86	No	No	0	7	5
376	R:R:G216	R:R:S219	1.86	No	No	0	2	5
377	R:R:G151	R:R:V150	1.84	No	No	0	8	5
378	L:L:G10	L:L:T13	1.82	No	No	0	0	0
379	R:R:A158	R:R:A399	1.79	No	No	0	7	8
380	R:R:G248	R:R:I323	1.76	No	No	0	8	8
381	R:R:G318	R:R:I317	1.76	No	Yes	0	4	7
382	R:R:C85	R:R:V100	1.71	No	Yes	2	9	7
383	R:R:C126	R:R:V100	1.71	Yes	Yes	2	9	7
384	R:R:G168	R:R:L167	1.71	No	No	0	1	3
385	R:R:A92	R:R:V95	1.7	No	No	0	5	5
386	R:R:I308	R:R:P283	1.69	No	No	0	8	5
387	L:L:E21	L:L:G22	1.64	Yes	No	0	0	0
388	R:R:E107	R:R:G108	1.64	No	No	0	5	9
389	R:R:C341	R:R:I345	1.64	No	No	0	4	5
390	R:R:V100	R:R:V83	1.6	Yes	No	0	7	5
391	R:R:V327	R:R:V331	1.6	Yes	No	0	9	8
392	R:R:S352	R:R:T353	1.6	No	No	0	9	9
393	R:R:G98	R:R:H99	1.59	No	Yes	0	4	4
394	L:L:L20	R:R:A208	1.58	No	No	0	0	4
395	R:R:E76	R:R:P77	1.57	No	No	0	1	4
396	R:R:C62	R:R:D74	1.56	No	Yes	0	9	3
397	R:R:C347	R:R:D344	1.56	No	No	0	7	7
398	R:R:I272	R:R:S271	1.55	Yes	No	0	6	3
399	R:R:I400	R:R:V405	1.54	No	No	0	6	6
400	R:R:K336	R:R:V332	1.52	No	No	0	6	6
401	L:L:A24	R:R:E68	1.51	No	No	0	0	4
402	R:R:A368	R:R:E387	1.51	No	No	0	6	8
403	R:R:L349	R:R:S352	1.5	No	No	0	9	9
404	R:R:K351	R:R:T355	1.5	No	No	0	8	8
405	L:L:T11	R:R:L142	1.47	Yes	No	0	0	3
406	L:L:D15	L:L:S14	1.47	No	No	0	0	0
407	R:R:D114	R:R:S116	1.47	No	No	0	4	5
408	R:R:D59	R:R:T58	1.45	No	No	0	3	1
409	R:R:I330	R:R:K334	1.45	No	No	0	9	9
410	L:L:E21	L:L:S18	1.44	Yes	No	0	0	0
411	R:R:E127	R:R:S124	1.44	No	No	0	2	5
412	R:R:E138	R:R:S136	1.44	No	No	0	2	1
413	R:R:E139	R:R:S136	1.44	No	No	0	2	1
414	R:R:I196	R:R:L192	1.43	No	No	0	5	3
415	R:R:I272	R:R:L268	1.43	Yes	No	0	6	2
416	R:R:I317	R:R:L314	1.43	Yes	No	0	7	4
417	R:R:I345	R:R:L335	1.43	No	No	0	5	8
418	R:R:Q410	R:R:V405	1.43	No	No	0	7	6
419	R:R:L339	R:R:M340	1.41	No	No	0	7	5
420	R:R:K346	R:R:L349	1.41	No	No	0	6	9
421	R:R:L224	R:R:L228	1.38	No	No	0	3	4
422	R:R:L335	R:R:L339	1.38	No	No	0	8	7
423	R:R:L111	R:R:Q112	1.33	No	No	0	4	3
424	R:R:L218	R:R:Q221	1.33	No	No	0	3	4
425	R:R:F169	R:R:S416	1.32	Yes	No	0	7	5
426	R:R:N407	R:R:Q410	1.32	No	No	0	6	7
427	R:R:R102	R:R:V81	1.31	Yes	No	0	8	6
428	R:R:A185	R:R:W274	1.3	No	Yes	0	3	9
429	R:R:E125	R:R:E128	1.27	No	No	0	5	3
430	R:R:L217	R:R:R40	1.21	No	No	0	4	2
431	R:R:N82	R:R:Y101	1.16	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:T11	6.4425	4	0	0
2	L:L:F12	6.14	5	7	0
3	L:L:E21	5.928	5	2	0
4	R:R:L32	4.3975	4	10	4
5	R:R:W33	8.22	4	8	3
6	R:R:E34	5.535	4	8	4
7	R:R:Y42	8.724	5	2	6
8	R:R:R43	10.1883	6	2	4
9	R:R:C46	6.6775	4	2	8
10	R:R:Y69	5.322	5	2	6
11	R:R:C71	4.2225	4	2	9
12	R:R:W72	9.764	5	4	9
13	R:R:D74	6.4375	4	0	3
14	R:R:P86	6.625	4	2	8
15	R:R:Y88	9.196	5	2	5
16	R:R:W91	5.3325	4	2	4
17	R:R:H99	6.9025	4	0	4
18	R:R:V100	3.0375	4	2	7
19	R:R:R102	10.68	5	4	8
20	R:R:F103	5.5775	4	4	4
21	R:R:P119	4.8975	4	4	6
22	R:R:W120	8.15571	7	4	5
23	R:R:C126	3.8625	4	2	9
24	R:R:Y145	5.588	5	7	5
25	R:R:Y148	7.288	5	3	7
26	R:R:Y152	6.84167	6	3	7
27	R:R:F156	4.1575	4	1	7
28	R:R:L159	4.01333	6	1	9
29	R:R:L166	5.1675	4	1	8
30	R:R:F169	5.1575	4	1	7
31	R:R:L172	3.7125	4	1	9
32	R:R:R176	4.47	5	1	9
33	R:R:N177	3.8025	4	1	9
34	R:R:I179	4.298	5	1	8
35	R:R:F184	4.09667	6	1	8
36	R:R:F187	9.112	5	1	8
37	R:R:R190	7.46	4	0	8
38	R:R:D222	4.9725	4	6	6
39	R:R:Y241	8.47	4	1	8
40	R:R:W243	12.644	5	9	9
41	R:R:V246	4.6275	4	0	8
42	R:R:E247	7.7925	4	0	9
43	R:R:Y250	7.858	5	1	8
44	R:R:Y269	6.192	5	0	7
45	R:R:I272	2.28	4	0	6
46	R:R:W274	6.84	7	9	9
47	R:R:F280	7.4875	4	0	5
48	R:R:W284	5.40167	6	6	8
49	R:R:K288	8.585	4	6	8
50	R:R:C296	3.9325	4	0	9
51	R:R:W297	6.55	6	6	8
52	R:R:W306	4.995	4	6	6
53	R:R:I317	2.74	5	1	7
54	R:R:F324	7.346	5	5	9
55	R:R:V327	3.38	4	5	9
56	R:R:L356	5.34	4	5	9
57	R:R:L359	9.0325	4	5	9
58	R:R:L360	5.3975	4	5	9
59	R:R:E364	6.63	4	1	8
60	R:R:F367	8.265	4	0	7
61	R:R:R380	5.1025	4	0	5
62	R:R:K383	5.5425	4	3	7
63	R:R:L384	4.56	4	3	5
64	R:R:Q394	7.535	4	1	9
65	R:R:Y402	7.8475	4	0	8
66	R:R:C403	3.6075	4	1	9
67	R:R:E412	8.445	4	1	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:L20	L:L:V16	10.6732	2.98	No	No	0	0	0
2	L:L:L20	R:R:L32	12.0527	4.15	No	Yes	0	0	4
3	R:R:L32	R:R:V36	83.8787	2.98	Yes	No	0	4	2
4	R:R:V36	R:R:Y220	84.3969	12.62	No	No	0	2	3
5	R:R:W33	R:R:Y220	86.3436	12.54	Yes	No	0	3	3
6	R:R:T298	R:R:W33	87.0707	12.13	No	Yes	8	5	3
7	R:R:C296	R:R:T298	89.8811	3.38	Yes	No	0	9	5
8	R:R:C296	R:R:D222	90.6972	3.11	Yes	Yes	0	9	6
9	R:R:D222	R:R:W297	89.5769	6.7	Yes	Yes	6	6	8
10	R:R:G285	R:R:W297	98.6799	2.81	No	Yes	0	5	8
11	R:R:G285	R:R:L231	98.8539	3.42	No	No	0	5	5
12	R:R:L231	R:R:V281	99.0254	2.98	No	No	0	5	6
13	R:R:F280	R:R:V281	99.1943	2.62	Yes	No	0	5	6
14	R:R:F280	R:R:Y242	99.6854	7.22	Yes	No	0	5	6
15	R:R:V276	R:R:Y242	100	7.57	No	No	0	3	6
16	R:R:I272	R:R:V276	76.9119	3.07	Yes	No	0	6	3
17	R:R:I272	R:R:V246	77.0434	3.07	Yes	Yes	0	6	8
18	R:R:V246	R:R:W243	25.2282	8.58	Yes	Yes	0	8	9
19	R:R:S186	R:R:W243	23.2325	7.41	No	Yes	9	9	9
20	R:R:N240	R:R:S186	44.7427	5.96	No	No	0	9	9
21	R:R:N240	R:R:R190	39.7703	9.64	No	Yes	0	9	8
22	R:R:R190	R:R:Y152	33.5654	4.12	Yes	Yes	0	8	7
23	R:R:Y148	R:R:Y152	20.0727	15.89	Yes	Yes	3	7	7
24	R:R:P277	R:R:V276	23.957	3.53	No	No	0	9	3
25	R:R:P277	R:R:Y235	23.2841	8.34	No	No	0	9	9
26	R:R:W274	R:R:Y235	23.2557	6.75	Yes	No	0	9	9
27	R:R:S186	R:R:W274	22.0439	4.94	No	Yes	9	9	9
28	R:R:L32	R:R:T35	77.1813	2.95	Yes	No	10	4	5
29	L:L:E21	R:R:P90	76.6231	7.86	Yes	No	0	0	4
30	R:R:P90	R:R:T35	76.9944	8.74	No	No	0	4	5
31	L:L:E21	R:R:L89	63.2787	13.25	Yes	No	2	0	5
32	L:L:E21	R:R:W91	12.2138	5.45	Yes	Yes	2	0	4
33	R:R:E68	R:R:F66	10.3135	2.33	No	No	0	4	7
34	R:R:F66	R:R:R43	11.5099	18.17	No	Yes	2	7	4
35	R:R:L89	R:R:Y88	63.182	10.55	No	Yes	2	5	5
36	R:R:Y42	R:R:Y88	39.497	13.9	Yes	Yes	2	6	5
37	R:R:Y69	R:R:Y88	11.3475	3.97	Yes	Yes	2	6	5
38	R:R:E127	R:R:W91	10.6307	3.27	No	Yes	0	2	4
39	R:R:C71	R:R:Y42	26.9583	2.69	Yes	Yes	2	9	6
40	R:R:C71	R:R:L50	27.3979	3.17	Yes	No	0	9	4
41	R:R:L50	R:R:R64	26.8139	9.72	No	No	0	4	4
42	R:R:D53	R:R:R64	25.6382	3.57	No	No	0	3	4
43	R:R:D53	R:R:P54	25.0464	4.83	No	No	0	3	2
44	R:R:P54	R:R:P55	24.4521	1.95	No	No	0	2	1
45	R:R:P55	R:R:P56	23.8552	1.95	No	No	0	1	1
46	R:R:D74	R:R:P56	20.132	4.83	Yes	No	0	3	1
47	R:R:C62	R:R:D74	17.7792	1.56	No	Yes	0	9	3
48	R:R:C62	R:R:W110	16.5236	6.53	No	No	0	9	9
49	R:R:W110	R:R:W120	11.274	8.43	No	Yes	4	9	5
50	R:R:P86	R:R:Y88	11.2057	6.95	Yes	Yes	2	8	5
51	R:R:C126	R:R:Y69	18.3259	2.69	Yes	Yes	2	9	6
52	R:R:C126	R:R:C85	13.2013	7.28	Yes	No	2	9	9
53	R:R:C85	R:R:G98	11.3771	1.96	No	No	0	9	4
54	R:R:C126	R:R:V100	13.2013	1.71	Yes	Yes	2	9	7
55	R:R:L388	R:R:Y148	17.8411	7.03	No	Yes	3	7	7
56	R:R:L384	R:R:L388	16.0801	2.77	Yes	No	3	5	7
57	R:R:F187	R:R:N240	19.8561	16.92	Yes	No	0	8	9
58	R:R:F187	R:R:L159	16.8936	3.65	Yes	Yes	1	8	9
59	R:R:L166	R:R:N177	15.4007	4.12	Yes	Yes	1	8	9
60	R:R:I179	R:R:V246	43.2369	3.07	Yes	Yes	0	8	8
61	R:R:F187	R:R:L183	14.4518	6.09	Yes	No	0	8	9
62	R:R:E247	R:R:L183	16.9271	3.98	Yes	No	0	9	9
63	R:R:E247	R:R:I179	31.455	6.83	Yes	Yes	0	9	8
64	R:R:I179	R:R:Y250	11.9676	6.04	Yes	Yes	1	8	8
65	R:R:V246	R:R:Y269	15.1867	3.79	Yes	Yes	0	8	7
66	R:R:Y250	R:R:Y269	11.9998	9.93	Yes	Yes	0	8	7
67	R:R:E247	R:R:L359	27.0524	9.28	Yes	Yes	0	9	9
68	R:R:L356	R:R:L359	16.0053	2.77	Yes	Yes	5	9	9
69	R:R:K383	R:R:L384	10.8021	2.82	Yes	Yes	3	7	5
70	R:R:R176	R:R:Y250	21.6829	3.09	Yes	Yes	1	9	8
71	R:R:N177	R:R:R176	21.7383	3.62	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E9	R:R:Y148	3.37	0	No	Yes	0	7	0	1
L:L:E9	R:R:K197	2.7	0	No	No	0	6	0	1
L:L:T11	R:R:L141	16.21	0	Yes	No	0	5	0	1
L:L:T11	R:R:Y145	3.75	0	Yes	Yes	0	5	0	1
L:L:F12	R:R:Y145	7.22	7	Yes	Yes	0	5	0	1
L:L:F12	R:R:D198	5.97	7	Yes	No	0	7	0	1
L:L:F12	R:R:L201	3.65	7	Yes	No	0	7	0	1
L:L:F12	R:R:K202	9.93	7	Yes	No	0	4	0	1
L:L:T13	R:R:S31	9.59	0	No	No	0	4	0	1
L:L:V16	R:R:L201	2.98	7	No	No	0	7	0	1
L:L:S17	R:R:L32	7.51	10	No	Yes	0	4	0	1
L:L:S17	R:R:T35	6.4	10	No	No	0	5	0	1
L:L:Y19	R:R:Y205	5.96	0	No	No	0	3	0	1
L:L:L20	R:R:L32	4.15	0	No	Yes	0	4	0	1
L:L:E21	R:R:L89	13.25	2	Yes	No	0	5	0	1
L:L:E21	R:R:P90	7.86	2	Yes	No	0	4	0	1
L:L:E21	R:R:W91	5.45	2	Yes	Yes	0	4	0	1
L:L:Q23	R:R:Q211	6.4	11	No	No	0	4	0	1
L:L:Q23	R:R:W214	8.76	11	No	No	0	1	0	1
L:L:A25	R:R:Y69	2.67	0	No	Yes	0	6	0	1
L:L:E27	R:R:Q211	19.11	11	No	No	0	4	0	1
L:L:F28	R:R:E68	7	0	No	No	0	4	0	1
L:L:F28	R:R:W214	5.01	0	No	No	0	1	0	1
L:L:I29	R:R:L118	5.71	0	No	No	0	4	0	1
R:R:S31	R:R:W33	4.94	8	No	Yes	4	3	1	2
R:R:E34	R:R:S31	5.75	8	Yes	No	4	4	2	1
R:R:L32	R:R:T35	2.95	10	Yes	No	4	5	1	1
R:R:L32	R:R:V36	2.98	10	Yes	No	4	2	1	2
R:R:E34	R:R:W33	3.27	8	Yes	Yes	4	3	2	2
R:R:P90	R:R:T35	8.74	0	No	No	4	5	1	1
R:R:P86	R:R:Y69	13.91	2	Yes	Yes	8	6	2	1
R:R:Y69	R:R:Y88	3.97	2	Yes	Yes	6	5	1	2
R:R:C126	R:R:Y69	2.69	2	Yes	Yes	9	6	2	1
R:R:E127	R:R:Y69	3.37	0	No	Yes	2	6	2	1
R:R:P86	R:R:Y88	6.95	2	Yes	Yes	8	5	2	2
R:R:C126	R:R:P86	3.77	2	Yes	Yes	9	8	2	2
R:R:L89	R:R:Y88	10.55	2	No	Yes	5	5	1	2
R:R:L89	R:R:W91	7.97	2	No	Yes	5	4	1	1
R:R:E127	R:R:W91	3.27	0	No	Yes	2	4	2	1
R:R:K130	R:R:W91	4.64	0	No	Yes	1	4	2	1
R:R:K113	R:R:L118	2.82	0	No	No	4	4	2	1
R:R:L118	R:R:P119	8.21	0	No	Yes	4	6	1	2
R:R:I146	R:R:Y145	3.63	0	No	Yes	4	5	2	1
R:R:T149	R:R:Y145	8.74	0	No	Yes	7	5	2	1
R:R:D198	R:R:Y145	4.6	7	No	Yes	7	5	1	1
R:R:Y148	R:R:Y152	15.89	3	Yes	Yes	7	7	1	2
R:R:V194	R:R:Y148	3.79	3	No	Yes	7	7	2	1
R:R:L388	R:R:Y148	7.03	3	No	Yes	7	7	2	1
R:R:S392	R:R:Y148	6.36	3	No	Yes	9	7	2	1
R:R:V194	R:R:Y152	5.05	3	No	Yes	7	7	2	2
R:R:S392	R:R:Y152	8.9	3	No	Yes	9	7	2	2
R:R:K202	R:R:Y205	7.17	0	No	No	4	3	1	1
R:R:E68	R:R:F66	2.33	0	No	No	4	7	1	2
L:L:L20	R:R:A208	1.58	0	No	No	0	4	0	1
L:L:A24	R:R:E68	1.51	0	No	No	0	4	0	1
L:L:T11	R:R:L142	1.47	0	Yes	No	0	3	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9IVG_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.62
Number of Linked Nodes	372
Number of Links	431
Number of Hubs	67
Number of Links mediated by Hubs	238
Number of Communities	11
Number of Nodes involved in Communities	96
Number of Links involved in Communities	129

Path Summary
Number Of Nodes in MetaPath	72
Number Of Links MetaPath	71
Number of Shortest Paths	124116
Length Of Smallest Path	3
Average Path Length	23.0336
Length of Longest Path	51
Minimum Path Strength	1.375
Average Path Strength	5.99522
Maximum Path Strength	19.045
Minimum Path Correlation	0.7
Average Path Correlation	0.953723
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.22222
Average % Of Corr. Nodes	49.2944
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.1754
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• monosaccharide metabolic process • regulation of cellular process • positive regulation of biological process • gluconeogenesis • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • small molecule metabolic process • regulation of carbohydrate metabolic process • regulation of glucose metabolic process • positive regulation of cellular process • positive regulation of gluconeogenesis • regulation of biosynthetic process • carbohydrate metabolic process • regulation of biological process • small molecule biosynthetic process • carbohydrate biosynthetic process • biological regulation • hexose metabolic process • primary metabolic process • monosaccharide biosynthetic process • hexose biosynthetic process • positive regulation of glucose metabolic process • biosynthetic process • regulation of gluconeogenesis • metabolic process • cellular process • positive regulation of carbohydrate metabolic process • regulation of carbohydrate biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • glucose metabolic process • cellular response to stimulus • positive regulation of cell communication • positive regulation of signal transduction • response to stimulus • signaling • regulation of signal transduction • intracellular signal transduction • cell communication • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of biological process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • negative regulation of cellular process • apoptotic process • programmed cell death • cellular response to nitrogen compound • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular response to hormone stimulus • response to activity • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • protein kinase A signaling • negative regulation of execution phase of apoptosis • regulation of execution phase of apoptosis • execution phase of apoptosis • behavior • multicellular organismal process • feeding behavior • adenylate cyclase-activating G protein-coupled receptor signaling pathway • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of biological quality • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • positive regulation of establishment of protein localization • carbohydrate homeostasis • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • positive regulation of peptide hormone secretion • intracellular glucose homeostasis • cellular response to carbohydrate stimulus • chemical homeostasis • response to glucose • glucose homeostasis • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • homeostatic process • positive regulation of secretion by cell • positive regulation of protein transport • positive regulation of hormone secretion • response to monosaccharide • response to carbohydrate • positive regulation of secretion • cellular response to hexose stimulus • intracellular chemical homeostasis • cellular response to monosaccharide stimulus • positive regulation of peptide secretion • cellular response to glucose stimulus • positive regulation of protein secretion • response to hexose • cellular homeostasis • positive regulation of transport • regulation of insulin secretion involved in cellular response to glucose stimulus • regulation of calcium ion import • regulation of calcium ion transport • positive regulation of calcium ion transport • positive regulation of calcium ion import • regulation of monoatomic ion transport • calcium ion transport • metal ion transport • positive regulation of monoatomic ion transport • monoatomic ion transport • calcium ion import • monoatomic cation transport • regulation of metal ion transport • cell periphery • cellular anatomical structure • plasma membrane • membrane • membrane-bounded organelle • intracellular anatomical structure • membrane-enclosed lumen • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle lumen • endoplasmic reticulum lumen • intracellular organelle • organelle lumen • organelle
Gene Ontology	Cellular Component	• cell periphery • cellular anatomical structure • plasma membrane • membrane • membrane-bounded organelle • intracellular anatomical structure • membrane-enclosed lumen • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle lumen • endoplasmic reticulum lumen • intracellular organelle • organelle lumen • organelle • endoplasmic reticulum • cytoplasm • extracellular region • vesicle lumen • intracellular vesicle • cytoplasmic vesicle lumen • secretory granule lumen • cytoplasmic vesicle • secretory granule • secretory vesicle • vesicle • extracellular space • glucagon receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • amide binding • binding • peptide hormone binding • hormone binding • glucagon-like peptide 1 receptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • heart process • multicellular organismal process • system process • regulation of biological process • regulation of heart contraction • regulation of system process • circulatory system process • regulation of blood circulation • regulation of multicellular organismal process • heart contraction • blood circulation • regulation of blood pressure • positive regulation of blood pressure • cellular response to stimulus • regulation of cellular process • response to stimulus • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to stress • response to psychosocial stress • cell surface receptor signaling pathway • behavior • learning or memory • nervous system process • cognition • transport • secretion • regulation of hormone levels • cell-cell signaling • export from cell • hormone secretion • establishment of localization • localization • secretion by cell • signal release • hormone transport • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • protein localization • establishment of protein localization • cellular localization • nitrogen compound transport • protein targeting • protein transmembrane transport • cellular macromolecule localization • establishment of localization in cell • post-translational protein targeting to membrane, translocation • establishment of protein localization to endoplasmic reticulum • protein localization to endoplasmic reticulum • establishment of protein localization to membrane • intracellular protein transmembrane transport • intracellular transport • post-translational protein targeting to endoplasmic reticulum membrane • localization within membrane • protein localization to membrane • protein targeting to membrane • transmembrane transport • establishment of protein localization to organelle • protein transport • macromolecule localization • protein localization to organelle • intracellular protein transport • protein targeting to ER • negative regulation of blood pressure • D2 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • D1 dopamine receptor binding • molecular function activator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of cellular localization • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • developmental process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of chemical stimulus • sensory perception • sensory perception of smell • cellular response to nitrogen compound • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • developmental growth • growth • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • homeostatic process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • regulation of protein secretion • regulation of secretion • regulation of hormone secretion • regulation of peptide secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • amide transport • regulation of signaling • regulation of transport • regulation of peptide transport • regulation of establishment of protein localization • regulation of protein transport • peptide transport • regulation of insulin secretion • peptide hormone secretion • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • midbody • nucleus • intracellular membraneless organelle • nucleolus • membraneless organelle • nuclear lumen • cell cortex • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • Golgi apparatus subcompartment • organelle subcompartment • trans-Golgi network membrane • trans-Golgi network • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• FnI-like domain • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• FnI-like domain • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>9IVG_nogp_Chain_R S L W E T V Q K W R E Y R R Q C Q R S L T E D P P P A T D L F C N R T F D E Y A C W P D G E P G S F V N V S C P W Y L P W A S S V P Q G H V Y R F C T A E G L W L Q K D N S S L P W R D L S E C E E S K S S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L S C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S V L S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F V R V I C I V V S K L K A N L M C K T D I K C R L A K S T L T L I P L L G T H E V I F A H A R G T L R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	10.1038/s41421-024-00649-0
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	10.1073/pnas.2303696120
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	10.1073/pnas.2303696120
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	10.1016/j.apsb.2024.09.002
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	10.1021/jacs.4c12808
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	10.1073/pnas.2200155119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	10.1073/pnas.2200155119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	10.1073/pnas.2116506119
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	10.1073/pnas.2116506119
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	10.1038/s41467-022-28683-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	10.1038/s41467-021-27760-0
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	10.1038/s41589-021-00945-w
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	10.1038/s41467-021-24058-z
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	10.1038/s41467-021-24058-z
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	10.1016/j.str.2021.04.008
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	10.1073/pnas.2014879117
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	10.1038/s41422-020-0384-8
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	10.1038/s41589-020-0589-7
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	10.1038/s41586-019-1902-z
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	10.1038/nature25773
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	10.1038/nature22394
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378

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Download 9IVG_nogp.zip

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