psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D11	A:A:R13	9.53	No	No	0	2	4
2	A:A:E16	A:A:R20	19.77	No	No	0	4	3
3	A:A:K17	A:A:R20	4.95	No	No	0	4	3
4	A:A:Q19	B:B:D83	9.14	No	No	6	4	8
5	A:A:Q19	B:B:T86	5.67	No	No	6	4	6
6	A:A:Q19	B:B:N88	5.28	No	Yes	6	4	7
7	A:A:E21	A:A:K25	10.8	No	No	0	2	5
8	A:A:E27	A:A:N23	15.77	No	No	6	6	7
9	A:A:N23	B:B:N88	14.98	No	Yes	6	7	7
10	A:A:N23	B:B:K89	5.6	No	Yes	6	7	9
11	A:A:I26	B:B:K89	8.72	No	Yes	0	9	9
12	A:A:I26	B:B:A92	4.87	No	No	0	9	6
13	A:A:E27	B:B:K89	6.75	No	Yes	6	6	9
14	A:A:K32	A:A:Q29	4.07	No	No	0	4	4
15	A:A:L30	B:B:K78	5.64	No	No	0	5	8
16	A:A:K34	A:A:Q31	4.07	Yes	No	0	4	4
17	A:A:Q31	R:R:Q263	6.4	No	No	0	4	5
18	A:A:D33	B:B:K78	11.06	No	No	0	5	8
19	A:A:K34	A:A:R38	7.43	Yes	No	18	4	4
20	A:A:K34	B:B:L55	8.46	Yes	No	0	4	6
21	A:A:K34	R:R:E262	5.4	Yes	No	18	4	6
22	A:A:Q35	R:R:S261	4.33	No	No	0	3	7
23	A:A:Q35	R:R:Q263	6.4	No	No	0	3	5
24	A:A:R42	A:A:Y37	18.52	No	No	0	9	4
25	A:A:Y37	B:B:L55	5.86	No	No	0	4	6
26	A:A:Y37	B:B:A56	4	No	No	0	4	7
27	A:A:R38	R:R:E262	15.12	No	No	18	4	6
28	A:A:N218	A:A:T40	5.85	No	No	0	4	7
29	A:A:H220	A:A:T40	6.85	Yes	No	0	7	7
30	A:A:F219	A:A:H41	10.18	Yes	No	0	8	6
31	A:A:H41	A:A:T242	6.85	No	No	0	6	8
32	A:A:H41	A:A:I383	5.3	No	Yes	0	6	8
33	A:A:F222	A:A:R42	4.28	Yes	No	0	7	9
34	A:A:F219	A:A:L43	6.09	Yes	No	0	8	7
35	A:A:I245	A:A:L43	5.71	No	No	0	7	7
36	A:A:L44	A:A:L46	5.54	No	No	0	9	8
37	A:A:F238	A:A:L44	25.58	Yes	No	0	9	9
38	A:A:I244	A:A:L44	9.99	No	No	0	8	9
39	A:A:L45	A:A:M221	9.9	No	No	0	8	8
40	A:A:D223	A:A:L45	4.07	Yes	No	0	9	8
41	A:A:F246	A:A:L46	4.87	No	No	0	9	8
42	A:A:A48	A:A:R265	6.91	No	No	0	8	9
43	A:A:K53	A:A:S51	4.59	No	No	0	9	9
44	A:A:D223	A:A:K53	6.91	Yes	No	0	9	9
45	A:A:K53	A:A:V247	4.55	No	No	0	9	7
46	A:A:N54	A:A:T55	5.85	No	No	0	9	9
47	A:A:I56	A:A:Q59	4.12	No	Yes	0	7	9
48	A:A:I56	A:A:V247	4.61	No	No	7	7	7
49	A:A:I56	A:A:N292	4.25	No	Yes	7	7	9
50	A:A:R61	A:A:V57	7.85	No	No	0	8	7
51	A:A:D223	A:A:V57	5.84	Yes	No	0	9	7
52	A:A:M60	A:A:Q59	9.52	No	Yes	0	9	9
53	A:A:N371	A:A:Q59	7.92	Yes	Yes	0	9	9
54	A:A:F212	A:A:M60	6.22	No	No	0	9	9
55	A:A:M221	A:A:M60	8.66	No	No	0	8	9
56	A:A:R61	A:A:T210	11.64	No	No	0	8	7
57	A:A:I207	A:A:V224	6.14	No	No	0	9	9
58	A:A:I207	B:B:L117	7.14	No	No	0	9	9
59	A:A:F208	A:A:G225	4.52	No	No	0	5	9
60	A:A:E209	A:A:K211	14.85	No	No	15	9	4
61	A:A:E209	A:A:H220	7.39	No	Yes	15	9	7
62	A:A:E209	A:A:F222	7	No	Yes	15	9	7
63	A:A:M221	A:A:T210	7.53	No	No	0	8	7
64	A:A:H220	A:A:K211	19.65	Yes	No	15	7	4
65	A:A:F212	A:A:F219	13.93	No	Yes	0	9	8
66	A:A:F212	A:A:I372	7.54	No	No	0	9	8
67	A:A:N218	A:A:Q213	10.56	No	No	0	4	3
68	A:A:F376	A:A:V214	7.87	Yes	No	0	8	6
69	A:A:D215	A:A:F376	8.36	No	Yes	0	5	8
70	A:A:F219	A:A:V217	5.24	Yes	No	0	8	5
71	A:A:F219	A:A:F376	6.43	Yes	Yes	0	8	8
72	A:A:C379	A:A:F219	4.19	No	Yes	0	8	8
73	A:A:F222	A:A:H220	5.66	Yes	Yes	15	7	7
74	A:A:F222	B:B:W99	22.05	Yes	Yes	0	7	9
75	A:A:F238	A:A:V224	3.93	Yes	No	0	9	9
76	A:A:Q227	A:A:W234	7.67	No	No	3	9	9
77	A:A:Q227	B:B:N119	6.6	No	No	0	9	9
78	A:A:Q227	B:B:Y145	6.76	No	Yes	3	9	8
79	A:A:E230	A:A:R228	15.12	No	No	3	9	9
80	A:A:R228	B:B:T164	6.47	No	No	0	9	6
81	A:A:R228	B:B:D186	10.72	No	Yes	3	9	9
82	A:A:E230	B:B:D186	5.2	No	Yes	3	9	9
83	A:A:R231	A:A:W234	7	No	No	0	9	9
84	A:A:L272	A:A:R231	12.15	No	No	0	8	9
85	A:A:K233	A:A:R232	8.66	Yes	No	10	9	8
86	A:A:R232	B:B:C204	8.36	No	Yes	10	8	7
87	A:A:R232	B:B:D228	10.72	No	Yes	10	8	9
88	A:A:K233	B:B:M188	12.96	Yes	No	0	9	8
89	A:A:K233	B:B:C204	4.85	Yes	Yes	10	9	7
90	A:A:K233	B:B:D228	8.3	Yes	Yes	10	9	9
91	A:A:K233	B:B:N230	6.99	Yes	No	0	9	9
92	A:A:W234	B:B:Y145	5.79	No	Yes	3	9	8
93	A:A:I235	A:A:L282	4.28	No	Yes	0	9	9
94	A:A:Q236	A:A:W281	6.57	No	Yes	3	8	5
95	A:A:Q236	B:B:R314	5.84	No	Yes	3	8	8
96	A:A:C237	B:B:Y59	8.06	No	Yes	3	8	8
97	A:A:C237	B:B:M101	4.86	No	Yes	3	8	9
98	A:A:F238	A:A:V241	5.24	Yes	No	0	9	9
99	A:A:F238	B:B:W99	8.02	Yes	Yes	0	9	9
100	A:A:N239	B:B:K57	11.19	No	Yes	3	8	9
101	A:A:N239	B:B:W332	6.78	No	Yes	3	8	9
102	A:A:D240	B:B:K57	6.91	No	Yes	0	6	9
103	A:A:D240	B:B:W99	4.47	No	Yes	0	6	9
104	A:A:I245	A:A:V375	4.61	No	No	0	7	9
105	A:A:F246	A:A:L272	6.09	No	No	0	9	8
106	A:A:F246	A:A:F273	9.65	No	Yes	0	9	9
107	A:A:N292	A:A:V247	4.43	Yes	No	7	9	7
108	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
109	A:A:A249	A:A:K293	4.82	No	No	0	8	9
110	A:A:L297	A:A:S250	9.01	No	No	0	8	6
111	A:A:K293	A:A:S251	4.59	No	No	0	9	9
112	A:A:L296	A:A:S251	9.01	No	No	0	6	9
113	A:A:L297	A:A:S251	4.5	No	No	0	8	9
114	A:A:R265	A:A:S252	5.27	No	No	0	9	8
115	A:A:S306	A:A:Y253	5.09	No	No	0	7	8
116	A:A:Y253	A:A:Y311	9.93	No	No	0	8	6
117	A:A:L296	A:A:N254	4.12	No	No	0	6	9
118	A:A:K300	A:A:N254	8.39	No	No	0	9	9
119	A:A:N264	A:A:T263	4.39	No	No	0	9	6
120	A:A:N264	A:A:Q267	5.28	No	No	0	9	4
121	A:A:N264	A:A:Y311	6.98	No	No	0	9	6
122	A:A:A268	A:A:R265	4.15	No	No	0	9	9
123	A:A:I341	A:A:L266	4.28	No	No	0	8	8
124	A:A:L270	A:A:Q267	3.99	No	No	0	6	4
125	A:A:F345	A:A:L270	14.61	Yes	No	0	8	6
126	A:A:D274	A:A:K271	6.91	Yes	No	0	5	5
127	A:A:F273	A:A:W277	16.04	Yes	Yes	16	9	6
128	A:A:F273	A:A:V287	5.24	Yes	No	0	9	6
129	A:A:F273	A:A:F345	17.15	Yes	Yes	0	9	8
130	A:A:C359	A:A:F273	4.19	No	Yes	16	5	9
131	A:A:D274	A:A:N278	9.42	Yes	No	0	5	8
132	A:A:D274	A:A:I348	8.4	Yes	No	0	5	4
133	A:A:I276	A:A:L282	4.28	No	Yes	0	8	9
134	A:A:S349	A:A:W277	7.41	No	Yes	16	7	6
135	A:A:H357	A:A:W277	14.81	No	Yes	0	7	6
136	A:A:C359	A:A:W277	3.92	No	Yes	16	5	6
137	A:A:L282	A:A:N279	12.36	Yes	No	0	9	8
138	A:A:K280	A:A:W281	16.24	No	Yes	3	5	5
139	A:A:K280	B:B:D290	8.3	No	Yes	3	5	6
140	A:A:W281	B:B:D290	10.05	Yes	Yes	3	5	6
141	A:A:W281	B:B:R314	13.99	Yes	Yes	3	5	8
142	A:A:W281	B:B:W332	10.31	Yes	Yes	3	5	9
143	A:A:L282	A:A:T285	5.9	Yes	No	0	9	7
144	A:A:R283	A:A:R356	14.93	No	No	0	3	2
145	A:A:S286	A:A:Y360	5.09	No	Yes	8	8	8
146	A:A:I382	A:A:S286	7.74	No	No	8	6	8
147	A:A:L289	A:A:L291	8.3	No	No	0	9	8
148	A:A:F345	A:A:L289	4.87	Yes	No	0	8	9
149	A:A:L289	A:A:P361	4.93	No	No	0	9	5
150	A:A:F290	A:A:T364	7.78	Yes	Yes	7	9	9
151	A:A:F290	A:A:N371	6.04	Yes	Yes	7	9	9
152	A:A:F290	A:A:R374	4.28	Yes	Yes	7	9	4
153	A:A:F363	A:A:L291	4.87	Yes	No	0	5	8
154	A:A:N292	A:A:T364	7.31	Yes	Yes	7	9	9
155	A:A:D295	A:A:Q294	5.22	No	No	20	9	6
156	A:A:K338	A:A:Q294	5.42	Yes	No	0	5	6
157	A:A:C365	A:A:Q294	6.1	No	No	20	8	6
158	A:A:C365	A:A:D295	10.89	No	No	20	8	9
159	A:A:D295	A:A:V367	4.38	No	No	0	9	9
160	A:A:V301	A:A:V334	4.81	No	Yes	0	7	4
161	A:A:A337	A:A:V301	5.09	No	No	0	8	7
162	A:A:D331	A:A:L302	5.43	Yes	No	0	4	2
163	A:A:K305	A:A:S306	4.59	No	No	0	3	7
164	A:A:E309	A:A:K307	5.4	No	No	0	4	6
165	A:A:F315	A:A:I308	17.58	No	No	0	6	7
166	A:A:A316	A:A:E309	4.53	No	No	0	2	4
167	A:A:F312	A:A:F340	7.5	No	Yes	0	8	7
168	A:A:E314	A:A:R317	8.14	No	No	0	6	2
169	A:A:F315	A:A:R336	10.69	No	No	0	6	5
170	A:A:F315	A:A:F340	17.15	No	Yes	0	6	7
171	A:A:P321	A:A:Y318	8.34	Yes	No	0	5	6
172	A:A:F340	A:A:Y318	16.5	Yes	No	0	7	6
173	A:A:D343	A:A:Y318	9.2	No	No	0	3	6
174	A:A:D323	A:A:P321	6.44	No	Yes	0	4	5
175	A:A:P321	A:A:Y339	8.34	Yes	Yes	0	5	3
176	A:A:D323	A:A:R342	8.34	No	Yes	0	4	4
177	A:A:A324	A:A:Y339	5.34	No	Yes	0	3	3
178	A:A:E327	A:A:P328	4.72	No	No	0	4	1
179	A:A:E330	A:A:V334	11.41	Yes	Yes	0	3	4
180	A:A:E330	A:A:T335	4.23	Yes	No	0	3	4
181	A:A:E330	A:A:K338	6.75	Yes	Yes	0	3	5
182	A:A:D331	A:A:V334	5.84	Yes	Yes	0	4	4
183	A:A:T335	A:A:Y339	4.99	No	Yes	0	4	3
184	A:A:F363	A:A:K338	18.61	Yes	Yes	0	5	5
185	A:A:R342	A:A:Y339	9.26	Yes	Yes	12	4	3
186	A:A:F363	A:A:Y339	6.19	Yes	Yes	12	5	3
187	A:A:E344	A:A:F340	17.49	No	Yes	0	5	7
188	A:A:D343	A:A:R342	7.15	No	Yes	0	3	4
189	A:A:L346	A:A:R342	6.07	No	Yes	12	4	4
190	A:A:P361	A:A:R342	5.76	No	Yes	12	5	4
191	A:A:F363	A:A:R342	7.48	Yes	Yes	12	5	4
192	A:A:E344	A:A:R347	10.47	No	No	0	5	4
193	A:A:L346	A:A:P361	6.57	No	No	12	4	5
194	A:A:C359	A:A:S349	5.16	No	No	16	5	7
195	A:A:G353	A:A:H357	4.77	No	No	0	4	7
196	A:A:G355	A:A:Y358	4.35	No	No	0	2	4
197	A:A:Y358	A:A:Y360	8.94	No	Yes	8	4	8
198	A:A:R385	A:A:Y358	17.49	Yes	No	8	5	4
199	A:A:D378	A:A:Y360	14.94	No	Yes	0	7	8
200	A:A:D381	A:A:Y360	14.94	No	Yes	8	8	8
201	A:A:I382	A:A:Y360	7.25	No	Yes	8	6	8
202	A:A:R385	A:A:Y360	6.17	Yes	Yes	8	5	8
203	A:A:H362	A:A:R374	11.28	No	Yes	0	9	4
204	A:A:D378	A:A:H362	10.08	No	No	0	7	9
205	A:A:D368	A:A:T364	5.78	Yes	Yes	7	9	9
206	A:A:N371	A:A:T364	11.7	Yes	Yes	7	9	9
207	A:A:D368	A:A:E370	11.69	Yes	No	7	9	4
208	A:A:D368	A:A:N371	9.42	Yes	Yes	7	9	9
209	A:A:D368	A:A:R374	11.91	Yes	Yes	7	9	4
210	A:A:E370	A:A:R374	6.98	No	Yes	7	4	4
211	A:A:N371	A:A:R374	4.82	Yes	Yes	7	9	4
212	A:A:F376	A:A:R380	6.41	Yes	No	0	8	7
213	A:A:D381	A:A:R385	14.29	No	Yes	8	8	5
214	A:A:D381	R:R:K334	6.91	No	Yes	8	8	9
215	A:A:I383	A:A:M386	4.37	Yes	No	19	8	3
216	A:A:H387	A:A:I383	3.98	No	Yes	19	8	8
217	A:A:Q384	R:R:K334	5.42	No	Yes	0	6	9
218	A:A:R385	R:R:K334	16.09	Yes	Yes	8	5	9
219	A:A:R385	R:R:N338	9.64	Yes	No	0	5	6
220	A:A:H387	A:A:M386	3.94	No	No	19	8	3
221	A:A:M386	A:A:R389	6.2	No	No	0	3	4
222	A:A:H387	R:R:L254	23.14	No	No	0	8	8
223	A:A:L388	A:A:L394	4.15	No	No	0	8	8
224	A:A:L388	R:R:L255	6.92	No	No	0	8	8
225	A:A:L388	R:R:V331	4.47	No	No	0	8	8
226	A:A:Q390	R:R:R176	8.18	No	Yes	0	4	9
227	A:A:Y391	R:R:Y250	4.96	No	Yes	0	4	8
228	A:A:Y391	R:R:L251	10.55	No	No	0	4	9
229	A:A:E392	R:R:N406	9.2	No	No	21	6	9
230	A:A:E392	R:R:N407	9.2	No	No	0	6	6
231	A:A:E392	R:R:E408	7.61	No	No	21	6	9
232	A:A:L393	R:R:L356	6.92	No	No	0	8	9
233	A:A:L394	R:R:K334	4.23	No	Yes	0	8	9
234	B:B:E3	G:G:I9	5.47	No	No	0	5	2
235	B:B:L4	G:G:S8	6.01	No	No	0	4	4
236	B:B:E10	B:B:L7	3.98	Yes	No	2	8	8
237	B:B:L7	G:G:V16	8.94	No	Yes	2	8	7
238	B:B:E10	B:B:Q13	6.37	Yes	No	2	8	1
239	B:B:E10	B:B:L14	7.95	Yes	Yes	2	8	8
240	B:B:E10	G:G:V16	4.28	Yes	Yes	2	8	7
241	B:B:L14	B:B:Q13	3.99	Yes	No	2	8	1
242	B:B:L14	G:G:L19	4.15	Yes	No	0	8	9
243	B:B:D20	B:B:N16	6.73	No	No	0	2	1
244	B:B:I18	B:B:R22	6.26	Yes	Yes	2	7	6
245	B:B:I18	G:G:E22	5.47	Yes	No	2	7	9
246	B:B:I18	G:G:R27	8.77	Yes	Yes	2	7	8
247	B:B:D20	B:B:R19	10.72	No	No	0	2	4
248	B:B:K23	B:B:R19	12.38	No	No	0	2	4
249	B:B:A21	G:G:R27	4.15	No	Yes	0	4	8
250	B:B:D258	B:B:R22	17.87	Yes	Yes	2	7	6
251	B:B:Q259	B:B:R22	7.01	No	Yes	0	6	6
252	B:B:R22	G:G:R27	5.33	Yes	Yes	2	6	8
253	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
254	B:B:D27	G:G:K29	17.97	No	No	0	8	4
255	B:B:D27	G:G:V30	4.38	No	No	0	8	8
256	B:B:D27	G:G:S31	8.83	No	No	0	8	9
257	B:B:S31	B:B:T29	6.4	No	No	0	1	3
258	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
259	B:B:L30	B:B:T34	4.42	Yes	No	0	5	5
260	B:B:L261	B:B:L30	6.92	No	Yes	0	5	5
261	B:B:L30	B:B:M262	5.65	Yes	No	0	5	4
262	B:B:L30	G:G:A34	4.73	Yes	No	0	5	6
263	B:B:M262	B:B:S31	6.13	No	No	0	4	1
264	B:B:I37	B:B:T34	4.56	No	No	0	2	5
265	B:B:K301	B:B:T34	6.01	No	No	0	5	5
266	B:B:N35	B:B:N36	5.45	No	No	0	1	1
267	B:B:I37	B:B:N36	4.25	No	No	0	2	1
268	B:B:I43	B:B:V40	4.61	No	Yes	1	3	3
269	B:B:R283	B:B:V40	7.85	Yes	Yes	1	9	3
270	B:B:D298	B:B:V40	5.84	No	Yes	1	9	3
271	B:B:G306	B:B:R42	4.5	No	No	0	4	2
272	B:B:I43	B:B:L284	7.14	No	Yes	1	3	5
273	B:B:I43	B:B:V296	4.61	No	Yes	1	3	5
274	B:B:L308	B:B:M45	4.24	Yes	No	0	7	4
275	B:B:M45	B:B:V327	4.56	No	No	0	4	6
276	B:B:K337	B:B:T47	6.01	Yes	No	4	6	3
277	B:B:T47	B:B:W339	7.28	No	Yes	4	3	9
278	B:B:N340	B:B:R48	7.23	No	No	22	9	7
279	B:B:R48	G:G:N59	4.82	No	Yes	22	7	9
280	B:B:R52	B:B:T50	9.06	No	No	0	7	3
281	B:B:K337	B:B:T50	12.01	Yes	No	0	6	3
282	B:B:L51	B:B:W82	17.08	Yes	Yes	0	9	9
283	B:B:L336	B:B:L51	5.54	No	Yes	0	7	9
284	B:B:I338	B:B:L51	4.28	No	Yes	0	5	9
285	B:B:F335	B:B:R52	4.28	No	No	0	4	7
286	B:B:R52	R:R:R170	18.13	No	No	0	7	8
287	B:B:H54	B:B:I58	9.28	Yes	No	0	9	9
288	B:B:H54	B:B:S72	8.37	Yes	No	6	9	9
289	B:B:H54	B:B:S74	16.74	Yes	No	0	9	9
290	B:B:H54	B:B:I80	13.26	Yes	No	6	9	8
291	B:B:H54	B:B:W82	6.35	Yes	Yes	6	9	9
292	B:B:D76	B:B:L55	12.21	No	No	0	9	6
293	B:B:K57	B:B:Y59	7.17	Yes	Yes	3	9	8
294	B:B:K57	B:B:Q75	6.78	Yes	No	3	9	9
295	B:B:K57	B:B:W332	20.89	Yes	Yes	3	9	9
296	B:B:Q75	B:B:Y59	20.29	No	Yes	3	9	8
297	B:B:M101	B:B:Y59	5.99	Yes	Yes	3	9	8
298	B:B:W332	B:B:Y59	13.5	Yes	Yes	3	9	8
299	B:B:C317	B:B:M61	6.48	No	No	0	7	6
300	B:B:L336	B:B:M61	4.24	No	No	0	7	6
301	B:B:H62	B:B:R150	12.41	No	Yes	0	6	6
302	B:B:L70	B:B:W63	19.36	No	Yes	0	5	7
303	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
304	B:B:T321	B:B:W63	10.92	No	Yes	0	7	7
305	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
306	B:B:G64	B:B:Y105	5.79	No	Yes	0	5	6
307	B:B:D322	B:B:T65	5.78	No	No	0	1	1
308	B:B:D66	B:B:L69	9.5	No	No	0	8	5
309	B:B:S67	B:B:T321	7.99	No	No	24	5	7
310	B:B:D323	B:B:S67	8.83	No	No	24	7	5
311	B:B:D83	B:B:R68	13.1	No	No	0	8	5
312	B:B:R68	B:B:Y85	16.46	No	Yes	0	5	4
313	B:B:L69	B:B:Y105	7.03	No	Yes	0	5	6
314	B:B:L79	B:B:V71	4.47	Yes	Yes	11	7	8
315	B:B:C103	B:B:V71	6.83	No	Yes	0	8	8
316	B:B:V71	B:B:Y105	5.05	Yes	Yes	0	8	6
317	B:B:V112	B:B:V71	4.81	No	Yes	11	8	8
318	B:B:S72	B:B:W82	8.65	No	Yes	6	9	9
319	B:B:A73	B:B:V100	5.09	No	No	0	9	9
320	B:B:D76	B:B:S74	10.31	No	No	0	9	9
321	B:B:Q75	B:B:W99	6.57	No	Yes	0	9	9
322	B:B:D76	B:B:K78	8.3	No	No	0	9	8
323	B:B:I93	B:B:L79	4.28	Yes	Yes	0	7	7
324	B:B:L79	B:B:L95	8.3	Yes	Yes	11	7	8
325	B:B:L79	B:B:V112	4.47	Yes	No	11	7	8
326	B:B:C114	B:B:L79	6.35	No	Yes	11	8	7
327	B:B:I80	B:B:W82	16.44	No	Yes	6	8	9
328	B:B:I80	B:B:K89	5.82	No	Yes	6	8	9
329	B:B:H91	B:B:I81	6.63	No	No	0	5	7
330	B:B:I81	B:B:Y105	6.04	No	Yes	0	7	6
331	B:B:K89	B:B:W82	12.76	Yes	Yes	6	9	9
332	B:B:D83	B:B:T86	5.78	No	No	6	8	6
333	B:B:S84	B:B:Y85	5.09	No	Yes	23	5	4
334	B:B:S84	G:G:F61	6.61	No	Yes	23	5	8
335	B:B:Y85	G:G:P60	15.3	Yes	No	0	4	9
336	B:B:Y85	G:G:F61	9.28	Yes	Yes	23	4	8
337	B:B:N88	B:B:T86	7.31	Yes	No	6	7	6
338	B:B:H91	B:B:V90	5.54	No	No	0	5	5
339	B:B:H91	B:B:V133	9.69	No	No	0	5	4
340	B:B:I93	B:B:Y124	7.25	Yes	Yes	0	7	6
341	B:B:I93	B:B:V133	4.61	Yes	No	0	7	4
342	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
343	B:B:C114	B:B:L95	6.35	No	Yes	11	8	8
344	B:B:L95	B:B:Y124	7.03	Yes	Yes	11	8	6
345	B:B:D118	B:B:S97	8.83	No	No	0	9	8
346	B:B:L117	B:B:W99	9.11	No	Yes	0	9	9
347	B:B:M101	B:B:Y145	7.18	Yes	Yes	3	9	8
348	B:B:C149	B:B:T102	6.76	No	No	0	8	8
349	B:B:A106	B:B:F151	9.71	No	Yes	0	6	9
350	B:B:N110	B:B:S108	8.94	No	No	0	4	6
351	B:B:K127	B:B:N110	6.99	No	No	0	4	4
352	B:B:N125	B:B:Y111	9.3	No	No	0	4	4
353	B:B:L126	B:B:V112	7.45	No	No	0	5	8
354	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
355	B:B:C114	B:B:Y124	5.38	No	Yes	11	8	6
356	B:B:E138	B:B:I120	4.1	Yes	No	0	6	6
357	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
358	B:B:E138	B:B:S122	4.31	Yes	No	0	6	8
359	B:B:I123	B:B:S136	4.64	Yes	No	0	6	4
360	B:B:F151	B:B:I123	5.02	Yes	Yes	0	9	6
361	B:B:I123	B:B:I171	8.83	Yes	No	0	6	6
362	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
363	B:B:K127	B:B:L126	4.23	No	No	0	4	5
364	B:B:N132	B:B:T128	4.39	No	No	0	3	3
365	B:B:E130	B:B:R129	20.93	No	No	0	3	3
366	B:B:E130	B:B:N132	13.15	No	No	0	3	3
367	B:B:R134	B:B:V135	3.92	No	No	0	3	4
368	B:B:E138	B:B:V135	4.28	Yes	No	0	6	4
369	B:B:R137	B:B:S136	3.95	No	No	0	5	4
370	B:B:L139	B:B:W169	15.94	No	Yes	0	9	8
371	B:B:H142	B:B:L146	9	Yes	No	9	9	7
372	B:B:H142	B:B:T159	5.48	Yes	Yes	9	9	9
373	B:B:H142	B:B:S161	12.55	Yes	No	0	9	9
374	B:B:A167	B:B:H142	4.39	No	Yes	9	4	9
375	B:B:H142	B:B:W169	9.52	Yes	Yes	9	9	8
376	B:B:D163	B:B:T143	10.12	No	No	0	9	5
377	B:B:G162	B:B:Y145	8.69	No	Yes	3	9	8
378	B:B:D186	B:B:Y145	11.49	Yes	Yes	3	9	8
379	B:B:M188	B:B:Y145	5.99	No	Yes	0	8	8
380	B:B:L146	B:B:T159	4.42	No	Yes	9	7	9
381	B:B:M188	B:B:S147	7.67	No	No	0	8	9
382	B:B:C148	B:B:R150	5.57	No	Yes	0	6	6
383	B:B:C148	B:B:L190	4.76	No	No	0	6	5
384	B:B:L192	B:B:R150	4.86	No	Yes	0	5	6
385	B:B:F151	B:B:I157	6.28	Yes	No	0	9	7
386	B:B:D153	B:B:L152	4.07	No	Yes	25	5	3
387	B:B:L152	B:B:Q156	5.32	Yes	No	0	3	5
388	B:B:L152	B:B:T196	4.42	Yes	No	25	3	1
389	B:B:L152	B:B:R214	4.86	Yes	No	0	3	9
390	B:B:D153	B:B:D154	10.65	No	No	0	5	6
391	B:B:D153	B:B:T196	5.78	No	No	25	5	1
392	B:B:L168	B:B:Q156	9.32	Yes	No	0	6	5
393	B:B:D170	B:B:Q156	11.75	No	No	0	9	5
394	B:B:I157	B:B:T159	4.56	No	Yes	0	7	9
395	B:B:I157	B:B:I171	4.42	No	No	0	7	6
396	B:B:F199	B:B:V158	7.87	Yes	No	0	9	5
397	B:B:T159	B:B:W169	10.92	Yes	Yes	9	9	8
398	B:B:S160	B:B:V187	4.85	No	Yes	0	6	9
399	B:B:L190	B:B:S160	7.51	No	No	0	5	6
400	B:B:D186	B:B:G162	5.03	Yes	No	3	9	9
401	B:B:D163	B:B:T165	5.78	No	No	0	9	7
402	B:B:T165	B:B:T181	6.28	No	No	0	7	2
403	B:B:C166	B:B:F180	5.59	No	Yes	5	8	7
404	B:B:C166	B:B:V187	5.12	No	Yes	5	8	9
405	B:B:C166	B:B:F199	4.19	No	Yes	5	8	9
406	B:B:A167	B:B:W169	5.19	No	Yes	9	4	8
407	B:B:L168	B:B:T177	4.42	Yes	No	5	6	4
408	B:B:L168	B:B:T178	4.42	Yes	No	5	6	4
409	B:B:L168	B:B:V213	5.96	Yes	No	0	6	4
410	B:B:Q176	B:B:W169	19.71	No	Yes	0	4	8
411	B:B:D170	B:B:E172	11.69	No	No	0	9	6
412	B:B:D170	B:B:T173	8.67	No	No	0	9	5
413	B:B:Q176	B:B:T179	4.25	No	No	0	4	4
414	B:B:T177	B:B:T178	4.71	No	No	5	4	4
415	B:B:F180	B:B:T178	6.49	Yes	No	5	7	4
416	B:B:F180	B:B:F199	15	Yes	Yes	5	7	9
417	B:B:F180	B:B:W211	17.04	Yes	Yes	5	7	8
418	B:B:H183	B:B:V187	4.15	Yes	Yes	5	9	9
419	B:B:H183	B:B:S201	8.37	Yes	No	5	9	9
420	B:B:A203	B:B:H183	8.78	No	Yes	0	8	9
421	B:B:H183	B:B:K209	18.34	Yes	Yes	5	9	6
422	B:B:H183	B:B:W211	6.35	Yes	Yes	5	9	8
423	B:B:D205	B:B:T184	8.67	No	No	0	9	3
424	B:B:S201	B:B:V187	6.46	No	Yes	5	9	9
425	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
426	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
427	B:B:A193	B:B:F234	8.32	No	Yes	0	4	5
428	B:B:G238	B:B:P194	4.06	No	No	0	7	4
429	B:B:D195	B:B:R197	5.96	No	No	0	5	5
430	B:B:D212	B:B:L198	4.07	No	No	26	9	3
431	B:B:L198	B:B:R219	4.86	No	Yes	26	3	5
432	B:B:F199	B:B:W211	14.03	Yes	Yes	5	9	8
433	B:B:F199	B:B:V213	5.24	Yes	No	0	9	4
434	B:B:I232	B:B:V200	7.68	Yes	No	2	8	6
435	B:B:F234	B:B:V200	10.49	Yes	No	0	5	6
436	B:B:F241	B:B:V200	7.87	Yes	No	2	6	6
437	B:B:S201	B:B:W211	4.94	No	Yes	5	9	8
438	B:B:G202	B:B:I229	5.29	No	No	0	6	7
439	B:B:C204	B:B:D228	7.78	Yes	Yes	10	7	9
440	B:B:D205	B:B:S207	4.42	No	No	0	9	5
441	B:B:K209	B:B:W211	9.28	Yes	Yes	5	6	8
442	B:B:C218	B:B:K209	8.08	No	Yes	5	5	6
443	B:B:K209	B:B:T221	13.51	Yes	No	0	6	7
444	B:B:L210	B:B:Q220	5.32	No	Yes	0	5	7
445	B:B:L210	B:B:L255	13.84	No	No	0	5	6
446	B:B:C218	B:B:W211	5.22	No	Yes	5	5	8
447	B:B:D212	B:B:E215	5.2	No	No	0	9	3
448	B:B:D212	B:B:R219	13.1	No	Yes	26	9	5
449	B:B:R214	B:B:V213	5.23	No	No	0	9	4
450	B:B:E215	B:B:M217	9.47	No	No	0	3	3
451	B:B:M217	B:B:R219	4.96	No	Yes	0	3	5
452	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
453	B:B:F222	B:B:Q220	16.4	No	Yes	2	8	7
454	B:B:D258	B:B:Q220	11.75	Yes	Yes	2	7	7
455	B:B:Q220	G:G:E22	7.65	Yes	No	2	7	9
456	B:B:F222	B:B:F241	12.86	No	Yes	2	8	6
457	B:B:F222	B:B:F253	11.79	No	Yes	2	8	6
458	B:B:H225	B:B:I229	7.95	Yes	No	2	9	7
459	B:B:H225	B:B:T243	8.21	Yes	Yes	2	9	8
460	B:B:H225	B:B:S245	9.76	Yes	No	0	9	9
461	B:B:H225	B:B:R251	9.03	Yes	Yes	2	9	8
462	B:B:D247	B:B:E226	16.89	No	No	0	9	3
463	B:B:D228	B:B:S227	5.89	Yes	No	10	9	6
464	B:B:D246	B:B:S227	4.42	Yes	No	10	9	6
465	B:B:D228	B:B:D246	3.99	Yes	Yes	10	9	9
466	B:B:I229	B:B:T243	6.08	No	Yes	2	7	8
467	B:B:D246	B:B:N230	8.08	Yes	No	0	9	9
468	B:B:F241	B:B:I232	5.02	Yes	Yes	2	6	8
469	B:B:I232	B:B:T243	4.56	Yes	Yes	2	8	8
470	B:B:C233	B:B:F278	4.19	No	Yes	0	3	7
471	B:B:F235	B:B:P236	10.11	Yes	Yes	1	6	7
472	B:B:F235	B:B:N237	8.46	Yes	No	1	6	5
473	B:B:A240	B:B:F235	4.16	No	Yes	0	6	6
474	B:B:F235	B:B:F278	7.5	Yes	Yes	1	6	7
475	B:B:F235	B:B:G282	4.52	Yes	No	1	6	9
476	B:B:F235	G:G:L37	13.4	Yes	No	0	6	7
477	B:B:F235	G:G:Y40	6.19	Yes	Yes	1	6	6
478	B:B:F235	G:G:C41	4.19	Yes	No	1	6	7
479	B:B:F278	B:B:P236	7.22	Yes	Yes	1	7	7
480	B:B:G282	B:B:P236	4.06	No	Yes	1	9	7
481	B:B:P236	G:G:Y40	5.56	Yes	Yes	1	7	6
482	B:B:N237	B:B:N239	8.17	No	No	0	5	2
483	B:B:N237	G:G:Y40	8.14	No	Yes	1	5	6
484	B:B:N239	B:B:R256	15.67	No	No	0	2	9
485	B:B:F241	B:B:F253	11.79	Yes	Yes	2	6	6
486	B:B:F253	B:B:T243	7.78	Yes	Yes	2	6	8
487	B:B:D247	B:B:S245	4.42	No	No	0	9	9
488	B:B:D247	B:B:T249	5.78	No	No	0	9	6
489	B:B:R251	B:B:T249	12.94	Yes	No	0	8	6
490	B:B:S265	B:B:T249	4.8	No	No	0	2	6
491	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
492	B:B:C250	B:B:I273	4.91	No	No	0	8	6
493	B:B:F253	B:B:R251	4.28	Yes	Yes	2	6	8
494	B:B:E260	B:B:R251	20.93	No	Yes	2	6	8
495	B:B:R251	B:B:T263	5.17	Yes	No	0	8	1
496	B:B:L252	B:B:L261	8.3	No	No	0	7	5
497	B:B:L252	B:B:Y264	7.03	No	Yes	0	7	5
498	B:B:E260	B:B:F253	7	No	Yes	2	6	6
499	B:B:D254	B:B:R256	4.76	Yes	No	0	9	9
500	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
501	B:B:D254	B:B:L261	6.79	Yes	No	0	9	5
502	B:B:D254	G:G:A33	4.63	Yes	No	0	9	7
503	B:B:R256	G:G:I28	7.52	No	No	0	9	4
504	B:B:D258	G:G:E22	6.5	Yes	No	2	7	9
505	B:B:D258	G:G:R27	16.68	Yes	Yes	2	7	8
506	B:B:M262	B:B:Y264	7.18	No	Yes	0	4	5
507	B:B:L285	B:B:Y264	5.86	Yes	Yes	1	6	5
508	B:B:W297	B:B:Y264	6.75	Yes	Yes	1	8	5
509	B:B:H266	B:B:N268	17.86	No	No	0	4	4
510	B:B:H266	B:B:I269	3.98	No	Yes	0	4	4
511	B:B:I269	B:B:Y289	7.25	Yes	Yes	0	4	7
512	B:B:I269	B:B:R304	6.26	Yes	Yes	0	4	5
513	B:B:C271	B:B:D290	4.67	No	Yes	0	5	6
514	B:B:C271	B:B:D291	9.34	No	No	0	5	8
515	B:B:I273	B:B:Y289	10.88	No	Yes	0	6	7
516	B:B:S275	B:B:T274	4.8	No	No	0	8	8
517	B:B:R314	B:B:T274	11.64	Yes	No	0	8	8
518	B:B:L318	B:B:S275	4.5	No	No	0	6	8
519	B:B:L318	B:B:S277	6.01	No	No	0	6	5
520	B:B:F278	B:B:G282	6.02	Yes	No	1	7	9
521	B:B:F278	B:B:L285	6.09	Yes	Yes	1	7	6
522	B:B:L284	B:B:S279	4.5	Yes	No	0	5	9
523	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
524	B:B:K280	G:G:E47	9.45	No	No	0	1	3
525	B:B:S281	G:G:D48	5.89	No	Yes	0	9	9
526	B:B:D298	B:B:R283	7.15	No	Yes	1	9	9
527	B:B:L300	B:B:R283	8.5	No	Yes	1	6	9
528	B:B:R283	G:G:C41	4.18	Yes	No	1	9	7
529	B:B:R283	G:G:L51	6.07	Yes	Yes	0	9	6
530	B:B:L284	B:B:V296	5.96	Yes	Yes	1	5	5
531	B:B:L284	G:G:L51	4.15	Yes	Yes	0	5	6
532	B:B:L285	B:B:W297	4.56	Yes	Yes	1	6	8
533	B:B:L286	B:B:V296	4.47	No	Yes	0	7	5
534	B:B:L286	B:B:V327	4.47	No	No	0	7	6
535	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
536	B:B:C294	B:B:G288	3.92	No	No	0	5	7
537	B:B:D291	B:B:Y289	9.2	No	Yes	0	8	7
538	B:B:N295	B:B:Y289	13.96	Yes	Yes	1	6	7
539	B:B:W297	B:B:Y289	9.65	Yes	Yes	1	8	7
540	B:B:D290	B:B:R314	7.15	Yes	Yes	3	6	8
541	B:B:D291	B:B:N293	10.77	No	No	0	8	5
542	B:B:N293	B:B:N295	5.45	No	Yes	1	5	6
543	B:B:N293	B:B:V307	4.43	No	Yes	1	5	3
544	B:B:C294	B:B:L308	6.35	No	Yes	0	5	7
545	B:B:C294	B:B:V315	5.12	No	No	0	5	7
546	B:B:N295	B:B:W297	4.52	Yes	Yes	1	6	8
547	B:B:N295	B:B:R304	19.28	Yes	Yes	1	6	5
548	B:B:N295	B:B:V307	5.91	Yes	Yes	1	6	3
549	B:B:L308	B:B:V296	4.47	Yes	Yes	0	7	5
550	B:B:R304	B:B:W297	11	Yes	Yes	1	5	8
551	B:B:D298	B:B:K301	9.68	No	No	0	9	5
552	B:B:L300	G:G:C41	7.94	No	No	1	6	7
553	B:B:R304	B:B:V307	3.92	Yes	Yes	1	5	3
554	B:B:L308	B:B:W339	7.97	Yes	Yes	0	7	9
555	B:B:H311	B:B:V315	5.54	Yes	No	0	9	7
556	B:B:H311	B:B:T329	8.21	Yes	No	0	9	8
557	B:B:H311	B:B:S331	12.55	Yes	No	4	9	9
558	B:B:D333	B:B:H311	8.82	Yes	Yes	4	9	9
559	B:B:H311	B:B:K337	13.1	Yes	Yes	4	9	6
560	B:B:D312	B:B:D333	9.31	No	Yes	4	5	9
561	B:B:D312	R:R:H171	15.13	No	No	4	5	7
562	B:B:D312	R:R:K415	5.53	No	Yes	4	5	7
563	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
564	B:B:D333	B:B:N313	4.04	Yes	No	0	9	7
565	B:B:R314	B:B:W332	25.99	Yes	Yes	3	8	9
566	B:B:S316	B:B:W332	6.18	No	Yes	0	9	9
567	B:B:D323	B:B:T321	7.23	No	No	24	7	7
568	B:B:D323	B:B:M325	5.54	No	No	0	7	5
569	B:B:G324	G:G:P49	4.06	No	No	0	9	7
570	B:B:M325	G:G:P49	5.03	No	No	0	5	7
571	B:B:A326	G:G:F61	8.32	No	Yes	0	7	8
572	B:B:V327	G:G:L50	4.47	No	No	0	6	9
573	B:B:T329	B:B:W339	12.13	No	Yes	0	8	9
574	B:B:D333	B:B:S331	10.31	Yes	No	4	9	9
575	B:B:D333	B:B:F335	7.17	Yes	No	0	9	4
576	B:B:K337	B:B:W339	8.12	Yes	Yes	4	6	9
577	B:B:I338	G:G:F61	5.02	No	Yes	0	5	8
578	B:B:N340	G:G:N59	10.9	No	Yes	22	9	9
579	G:G:I9	G:G:R13	5.01	No	No	0	2	6
580	G:G:E17	G:G:Q18	10.19	No	No	0	6	9
581	G:G:I25	G:G:R27	7.52	No	Yes	0	2	8
582	G:G:I28	G:G:K32	4.36	No	No	0	4	5
583	G:G:D36	G:G:K32	5.53	No	No	0	5	5
584	G:G:H44	G:G:Y40	25.04	No	Yes	0	6	6
585	G:G:E47	G:G:H44	16	No	No	0	3	6
586	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
587	G:G:D48	G:G:L50	4.07	Yes	No	0	9	9
588	G:G:D48	G:G:L51	6.79	Yes	Yes	0	9	6
589	G:G:E58	G:G:V54	4.28	No	No	0	5	6
590	G:G:N59	G:G:V54	4.43	Yes	No	0	9	6
591	G:G:E58	G:G:P55	11	No	No	0	5	5
592	G:G:A56	G:G:R62	5.53	No	No	0	4	7
593	G:G:E58	G:G:S57	4.31	No	No	0	5	6
594	G:G:N59	G:G:P60	4.89	Yes	No	0	9	9
595	R:R:E139	R:R:S136	5.75	No	No	0	2	1
596	R:R:E138	R:R:E139	7.61	No	No	0	2	2
597	R:R:F381	R:R:Q140	28.11	No	No	0	4	4
598	R:R:Y145	R:R:Y148	9.93	No	Yes	13	5	7
599	R:R:D198	R:R:Y145	11.49	No	No	13	7	5
600	R:R:I146	R:R:I147	4.42	No	No	0	4	6
601	R:R:Y148	R:R:Y152	3.97	Yes	Yes	13	7	7
602	R:R:V194	R:R:Y148	5.05	No	Yes	13	7	7
603	R:R:D198	R:R:Y148	6.9	No	Yes	13	7	7
604	R:R:L388	R:R:Y148	14.07	No	Yes	0	7	7
605	R:R:F195	R:R:T149	7.78	No	No	0	7	7
606	R:R:F393	R:R:G151	9.03	No	No	0	7	8
607	R:R:R190	R:R:Y152	5.14	Yes	Yes	0	8	7
608	R:R:A191	R:R:Y152	4	No	Yes	0	7	7
609	R:R:V194	R:R:Y152	10.09	No	Yes	13	7	7
610	R:R:S392	R:R:Y152	5.09	No	Yes	0	9	7
611	R:R:F156	R:R:I188	7.54	No	No	0	7	7
612	R:R:F156	R:R:L192	8.53	No	No	0	7	3
613	R:R:F184	R:R:L159	10.96	Yes	No	0	8	9
614	R:R:I188	R:R:L159	9.99	No	No	0	7	9
615	R:R:A162	R:R:F184	4.16	No	Yes	0	9	8
616	R:R:F413	R:R:I165	6.28	No	No	0	5	8
617	R:R:L166	R:R:N177	5.49	Yes	No	0	8	9
618	R:R:L166	R:R:L181	6.92	Yes	No	0	8	6
619	R:R:F184	R:R:L166	4.87	Yes	Yes	27	8	8
620	R:R:C403	R:R:L166	6.35	No	Yes	27	9	8
621	R:R:L167	R:R:L181	5.54	No	No	0	3	6
622	R:R:F169	R:R:L172	7.31	Yes	No	4	7	9
623	R:R:E412	R:R:F169	23.32	Yes	Yes	4	8	7
624	R:R:F169	R:R:F413	9.65	Yes	No	0	7	5
625	R:R:F169	R:R:S416	7.93	Yes	No	4	7	5
626	R:R:E412	R:R:H171	11.08	Yes	No	4	8	7
627	R:R:H171	R:R:K415	7.86	No	Yes	4	7	7
628	R:R:L172	R:R:V409	4.47	No	No	0	9	9
629	R:R:E412	R:R:L172	10.6	Yes	No	4	8	9
630	R:R:H173	R:R:Y178	10.89	No	No	0	7	6
631	R:R:T175	R:R:Y250	7.49	No	Yes	0	7	8
632	R:R:E262	R:R:T175	9.88	No	No	0	6	7
633	R:R:F266	R:R:T175	3.89	Yes	No	0	6	7
634	R:R:N177	R:R:R176	8.44	No	Yes	0	9	9
635	R:R:R176	R:R:Y250	4.12	Yes	Yes	0	9	8
636	R:R:E408	R:R:R176	4.65	No	Yes	0	9	9
637	R:R:F266	R:R:Y178	8.25	Yes	No	0	6	6
638	R:R:I179	R:R:W243	4.7	No	Yes	0	8	9
639	R:R:E247	R:R:I179	5.47	Yes	No	0	9	8
640	R:R:F266	R:R:I179	5.02	Yes	No	0	6	8
641	R:R:E247	R:R:H180	12.31	Yes	No	0	9	9
642	R:R:H180	R:R:Y402	4.36	No	No	0	9	8
643	R:R:N182	R:R:W243	18.08	No	Yes	14	9	9
644	R:R:N182	R:R:V270	4.43	No	No	14	9	5
645	R:R:N182	R:R:W274	10.17	No	Yes	14	9	9
646	R:R:F187	R:R:L183	6.09	Yes	No	17	8	9
647	R:R:L183	R:R:L244	5.54	No	Yes	17	9	9
648	R:R:E247	R:R:L183	5.3	Yes	No	0	9	9
649	R:R:F184	R:R:V398	3.93	Yes	No	0	8	9
650	R:R:C403	R:R:F184	4.19	No	Yes	27	9	8
651	R:R:S186	R:R:W243	6.18	No	Yes	14	9	9
652	R:R:S186	R:R:W274	6.18	No	Yes	14	9	9
653	R:R:F187	R:R:N240	16.92	Yes	No	17	8	9
654	R:R:F187	R:R:L244	4.87	Yes	Yes	17	8	9
655	R:R:F187	R:R:Q394	9.37	Yes	No	0	8	9
656	R:R:C236	R:R:L189	6.35	No	No	0	5	7
657	R:R:R190	R:R:V237	3.92	Yes	No	0	8	6
658	R:R:N240	R:R:R190	12.05	No	Yes	0	9	8
659	R:R:R190	R:R:Y241	7.2	Yes	No	0	8	8
660	R:R:M233	R:R:S193	6.13	No	No	0	6	6
661	R:R:C236	R:R:S193	6.89	No	No	0	5	6
662	R:R:D198	R:R:V194	4.38	No	No	13	7	7
663	R:R:F230	R:R:K197	7.44	Yes	No	0	5	6
664	R:R:K197	R:R:M233	7.2	No	No	0	6	6
665	R:R:K202	R:R:Y205	10.75	No	No	0	4	3
666	R:R:M204	R:R:W203	4.65	No	No	0	3	3
667	R:R:T207	R:R:W203	7.28	Yes	No	0	3	3
668	R:R:M204	R:R:Y220	4.79	No	No	0	3	3
669	R:R:A208	R:R:L217	6.3	No	No	0	4	4
670	R:R:D215	R:R:Q213	11.75	No	No	0	3	4
671	R:R:D215	R:R:W214	4.47	No	No	0	3	1
672	R:R:D215	R:R:G216	5.03	No	No	0	3	2
673	R:R:L218	R:R:Q221	7.99	No	No	0	3	4
674	R:R:D222	R:R:E294	9.09	No	No	0	6	4
675	R:R:S223	R:R:S225	6.52	No	No	0	4	3
676	R:R:L224	R:R:R227	6.07	No	Yes	29	3	8
677	R:R:L224	R:R:Y289	7.03	No	No	29	3	3
678	R:R:C226	R:R:C296	7.28	No	No	0	9	9
679	R:R:R227	R:R:Y289	5.14	Yes	No	29	8	3
680	R:R:E294	R:R:R227	15.12	No	Yes	0	4	8
681	R:R:R227	R:R:W297	21.99	Yes	No	0	8	8
682	R:R:F230	R:R:Q234	9.37	Yes	Yes	28	5	7
683	R:R:F230	R:R:W284	5.01	Yes	Yes	28	5	8
684	R:R:F230	R:R:T298	10.38	Yes	No	0	5	5
685	R:R:M233	R:R:Q234	4.08	No	Yes	0	6	7
686	R:R:Q234	R:R:W284	5.48	Yes	Yes	28	7	8
687	R:R:I309	R:R:Q234	8.23	No	Yes	0	7	7
688	R:R:W274	R:R:Y235	6.75	Yes	No	0	9	9
689	R:R:L278	R:R:Y235	8.21	No	No	0	3	9
690	R:R:V281	R:R:Y235	6.31	No	No	0	6	9
691	R:R:L244	R:R:N240	5.49	Yes	No	17	9	9
692	R:R:I313	R:R:Y241	9.67	No	No	0	7	8
693	R:R:E364	R:R:Y241	11.22	No	No	0	8	8
694	R:R:L245	R:R:Y242	4.69	No	Yes	0	8	6
695	R:R:V276	R:R:Y242	7.57	No	Yes	0	3	6
696	R:R:P277	R:R:Y242	6.95	No	Yes	0	9	6
697	R:R:F280	R:R:Y242	10.32	No	Yes	30	5	6
698	R:R:P312	R:R:Y242	4.17	No	Yes	30	8	6
699	R:R:A316	R:R:Y242	5.34	No	Yes	0	7	6
700	R:R:V246	R:R:W243	8.58	No	Yes	0	8	9
701	R:R:V270	R:R:W243	4.9	No	Yes	14	5	9
702	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
703	R:R:W243	R:R:W274	24.37	Yes	Yes	14	9	9
704	R:R:G361	R:R:L244	5.13	No	Yes	0	9	9
705	R:R:L245	R:R:N320	5.49	No	No	0	8	9
706	R:R:E247	R:R:L359	11.93	Yes	No	0	9	9
707	R:R:G248	R:R:L360	5.13	No	Yes	0	8	9
708	R:R:L254	R:R:Y250	9.38	No	Yes	0	8	8
709	R:R:Y250	R:R:Y269	6.95	Yes	No	0	8	7
710	R:R:L251	R:R:V327	7.45	No	No	0	9	9
711	R:R:A256	R:R:Y252	5.34	No	No	0	6	8
712	R:R:I323	R:R:Y252	4.84	No	No	0	8	8
713	R:R:R326	R:R:Y252	7.2	No	No	0	8	8
714	R:R:F257	R:R:T253	6.49	No	No	0	5	7
715	R:R:L260	R:R:T253	5.9	No	No	0	7	7
716	R:R:L255	R:R:V327	4.47	No	No	0	8	9
717	R:R:I330	R:R:L255	5.71	No	No	0	9	8
718	R:R:A256	R:R:F257	8.32	No	No	0	6	5
719	R:R:I265	R:R:L260	5.71	No	No	0	5	7
720	R:R:S261	R:R:W264	4.94	No	No	0	7	5
721	R:R:Q263	R:R:R267	9.35	No	No	0	5	4
722	R:R:R267	R:R:W264	5	No	No	0	4	5
723	R:R:I265	R:R:Y269	10.88	No	No	0	5	7
724	R:R:F266	R:R:V270	5.24	Yes	No	0	6	5
725	R:R:I272	R:R:L268	4.28	No	No	0	6	2
726	R:R:I272	R:R:V276	4.61	No	No	0	6	3
727	R:R:G275	R:R:L278	5.13	No	No	0	6	3
728	R:R:F280	R:R:I309	6.28	No	No	0	5	7
729	R:R:F280	R:R:P312	18.78	No	No	30	5	8
730	R:R:K288	R:R:W284	13.92	No	Yes	0	8	8
731	R:R:V287	R:R:Y305	6.31	No	Yes	0	4	4
732	R:R:E292	R:R:K288	8.1	Yes	No	0	6	8
733	R:R:K288	R:R:W297	22.05	No	No	0	8	8
734	R:R:L290	R:R:Y291	5.86	No	No	0	3	3
735	R:R:Y291	R:R:Y305	9.93	No	Yes	0	3	4
736	R:R:D293	R:R:E292	5.2	No	Yes	0	7	6
737	R:R:E292	R:R:S301	4.31	Yes	No	0	6	3
738	R:R:N300	R:R:W306	18.08	No	No	0	6	6
739	R:R:N302	R:R:N304	10.9	No	No	31	5	3
740	R:R:N302	R:R:Y305	10.47	No	Yes	31	5	4
741	R:R:N304	R:R:Y305	9.3	No	Yes	31	3	4
742	R:R:R310	R:R:W306	13	Yes	No	0	6	6
743	R:R:L307	R:R:L311	6.92	No	No	0	7	4
744	R:R:L314	R:R:R310	8.5	No	Yes	0	4	6
745	R:R:F369	R:R:L314	4.87	Yes	No	0	4	4
746	R:R:F315	R:R:V319	6.55	No	No	0	4	6
747	R:R:E364	R:R:I317	6.83	No	No	0	8	7
748	R:R:L360	R:R:N320	4.12	Yes	No	0	9	9
749	R:R:F321	R:R:V365	11.8	No	No	0	6	6
750	R:R:F324	R:R:I328	6.28	Yes	No	0	9	7
751	R:R:F324	R:R:L356	7.31	Yes	No	0	9	9
752	R:R:F324	R:R:I357	6.28	Yes	No	32	9	8
753	R:R:F324	R:R:T362	7.78	Yes	No	32	9	7
754	R:R:I330	R:R:R326	10.02	No	No	0	9	8
755	R:R:I328	R:R:T353	7.6	No	No	0	7	9
756	R:R:I345	R:R:L335	4.28	No	No	0	5	8
757	R:R:D344	R:R:K346	6.91	No	No	0	7	6
758	R:R:C347	W:W:?1	36.37	No	No	0	7	0
759	R:R:K351	R:R:R348	12.38	No	No	0	8	8
760	R:R:R348	R:R:S352	11.86	No	No	0	8	9
761	R:R:A350	W:W:?1	8.33	No	No	0	8	0
762	R:R:L401	R:R:T355	7.37	No	No	0	8	8
763	R:R:T355	R:R:Y402	6.24	No	No	0	8	8
764	R:R:L356	R:R:L360	5.54	No	Yes	0	9	9
765	R:R:I357	R:R:T362	7.6	No	No	32	8	7
766	R:R:H363	R:R:I357	3.98	No	No	0	8	8
767	R:R:L359	R:R:L360	4.15	No	Yes	0	9	9
768	R:R:L359	R:R:Y402	24.62	No	No	0	9	8
769	R:R:F390	R:R:H363	15.84	No	No	0	6	8
770	R:R:H363	R:R:Q394	8.65	No	No	0	8	9
771	R:R:E364	R:R:T391	5.64	No	No	0	8	6
772	R:R:F367	R:R:I366	8.79	No	No	0	7	6
773	R:R:F367	R:R:T386	10.38	No	No	0	7	4
774	R:R:E387	R:R:F367	7	No	No	0	8	7
775	R:R:E387	R:R:K383	6.75	No	No	0	8	7
776	R:R:F385	R:R:S389	7.93	No	No	0	6	5
777	R:R:F390	R:R:T386	6.49	No	No	0	6	4
778	R:R:F393	R:R:S392	5.28	No	No	0	7	9
779	R:R:I400	R:R:L396	4.28	No	No	0	6	7
780	R:R:C403	R:R:F404	4.19	No	Yes	0	9	8
781	R:R:E408	R:R:N406	10.52	No	No	21	9	9
782	R:R:K415	R:R:L411	7.05	Yes	No	0	7	4
783	R:R:E412	R:R:K415	10.8	Yes	Yes	4	8	7
784	R:R:E412	R:R:S416	4.31	Yes	No	4	8	5
785	R:R:E418	R:R:R421	6.98	No	No	0	4	4
786	R:R:E423	R:R:W420	7.63	No	No	0	4	4
787	A:A:E15	A:A:Q12	3.82	No	No	0	6	2
788	R:R:S225	R:R:Y220	3.82	No	No	0	3	3
789	R:R:V249	R:R:Y269	3.79	No	No	0	6	7
790	A:A:F290	A:A:I288	3.77	Yes	No	0	9	9
791	R:R:F404	R:R:I161	3.77	Yes	No	0	8	4
792	R:R:F381	R:R:I382	3.77	No	No	0	4	4
793	R:R:F404	R:R:I400	3.77	Yes	No	0	8	6
794	B:B:I338	B:B:R49	3.76	No	No	0	5	7
795	R:R:W417	R:R:W420	3.75	No	No	0	5	4
796	R:R:A239	R:R:P277	3.74	No	No	0	8	9
797	A:A:G47	A:A:S51	3.71	No	No	0	9	9
798	A:A:K280	A:A:R283	3.71	No	No	0	5	3
799	A:A:G353	A:A:S352	3.71	No	No	0	4	5
800	B:B:G162	B:B:S161	3.71	No	No	0	9	9
801	B:B:G306	B:B:V296	3.68	No	Yes	0	4	5
802	R:R:G151	R:R:V150	3.68	No	No	0	8	5
803	A:A:F312	A:A:L266	3.65	No	No	0	8	8
804	B:B:C121	B:B:C149	3.64	No	No	9	8	8
805	B:B:G174	B:B:T173	3.64	No	No	0	4	5
806	B:B:L210	B:B:R219	3.64	No	Yes	0	5	5
807	R:R:L335	R:R:R348	3.64	No	No	0	8	8
808	R:R:L379	R:R:R376	3.64	No	No	0	3	5
809	B:B:I123	B:B:Y111	3.63	Yes	No	0	6	4
810	A:A:N377	A:A:R380	3.62	No	No	0	4	7
811	B:B:A60	B:B:C103	3.61	No	No	0	7	8
812	A:A:D223	A:A:F208	3.58	Yes	No	0	9	5
813	B:B:D66	B:B:R68	3.57	No	No	0	8	5
814	R:R:P137	R:R:S136	3.56	No	No	0	3	1
815	B:B:G244	B:B:I273	3.53	No	No	0	5	6
816	R:R:P283	R:R:V282	3.53	No	No	0	5	3
817	R:R:P358	R:R:V398	3.53	No	No	0	9	9
818	R:R:L144	R:R:Y148	3.52	No	Yes	0	6	7
819	R:R:I308	R:R:W284	3.52	No	Yes	0	8	8
820	A:A:P321	A:A:T320	3.5	Yes	No	0	5	1
821	B:B:G319	B:B:M61	3.49	No	No	0	5	6
822	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
823	A:A:D310	A:A:Y311	3.45	No	No	0	3	6
824	A:A:A48	A:A:S51	3.42	No	No	0	8	9
825	B:B:G115	B:B:L146	3.42	No	No	0	9	7
826	R:R:L218	R:R:W214	3.42	No	No	0	3	1
827	R:R:G285	R:R:L231	3.42	No	No	0	5	5
828	A:A:G52	A:A:N292	3.39	No	Yes	0	9	9
829	A:A:A269	A:A:V248	3.39	No	No	0	9	7
830	A:A:A298	A:A:V334	3.39	No	Yes	0	4	4
831	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
832	B:B:G144	B:B:N119	3.39	No	No	0	8	9
833	B:B:A231	B:B:V276	3.39	No	No	0	5	6
834	B:B:A257	G:G:V30	3.39	No	No	0	7	8
835	B:B:C148	B:B:T102	3.38	No	No	0	6	8
836	B:B:C121	B:B:T159	3.38	No	Yes	9	8	9
837	B:B:C149	B:B:T159	3.38	No	Yes	9	8	9
838	B:B:D246	B:B:G272	3.35	Yes	No	0	9	4
839	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
840	R:R:M397	R:R:P358	3.35	No	No	0	5	9
841	B:B:E215	B:B:G216	3.27	No	No	0	3	4
842	B:B:E260	B:B:G224	3.27	No	No	0	6	6
843	R:R:E418	R:R:W417	3.27	No	No	0	4	5
844	A:A:A243	A:A:I288	3.25	No	No	0	8	9
845	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
846	B:B:A28	B:B:I33	3.25	No	No	0	4	3
847	B:B:A140	B:B:I120	3.25	No	No	0	5	6
848	R:R:A238	R:R:I313	3.25	No	No	0	6	7
849	B:B:S277	B:B:V320	3.23	No	No	0	5	7
850	R:R:S352	R:R:V331	3.23	No	No	0	9	8
851	R:R:S206	R:R:T207	3.2	No	Yes	0	4	3
852	A:A:A337	A:A:L297	3.15	No	No	0	8	8
853	B:B:L7	G:G:A12	3.15	No	No	0	8	5
854	A:A:E330	A:A:P326	3.14	Yes	No	0	3	1
855	A:A:I383	R:R:S258	3.1	Yes	No	0	8	7
856	B:B:A193	B:B:D195	3.09	No	No	0	4	5
857	R:R:I146	R:R:V150	3.07	No	No	0	4	5
858	R:R:I323	R:R:V319	3.07	No	No	0	8	6
859	R:R:I400	R:R:V405	3.07	No	No	0	6	6
860	A:A:I244	A:A:T285	3.04	No	No	0	8	7
861	R:R:K336	R:R:V332	3.04	No	No	0	6	6
862	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
863	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
864	R:R:F187	R:R:G395	3.01	Yes	No	0	8	9
865	B:B:G310	R:R:R419	3	No	No	0	5	7
866	R:R:L181	R:R:S163	3	No	No	0	6	6
867	A:A:N278	A:A:S352	2.98	No	No	0	8	5
868	B:B:L285	B:B:V276	2.98	Yes	No	0	6	6
869	B:B:V307	R:R:L422	2.98	Yes	No	0	3	4
870	G:G:L15	G:G:V16	2.98	No	Yes	0	2	7
871	R:R:L231	R:R:V281	2.98	No	No	0	5	6
872	R:R:L349	R:R:V332	2.98	No	No	0	9	6
873	A:A:T350	R:R:L339	2.95	No	No	0	4	7
874	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
875	R:R:L217	R:R:T207	2.95	No	Yes	0	4	3
876	R:R:L349	R:R:T353	2.95	No	No	0	9	9
877	B:B:D163	B:B:S161	2.94	No	No	0	9	9
878	B:B:I37	G:G:M38	2.92	No	No	0	2	4
879	B:B:N125	B:B:T128	2.92	No	No	0	4	3
880	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
881	B:B:M217	G:G:M21	2.89	No	No	0	3	1
882	A:A:P313	A:A:R317	2.88	No	No	0	6	2
883	A:A:K28	A:A:K32	2.87	No	No	0	4	4
884	R:R:Q410	R:R:V405	2.87	No	No	0	7	6
885	B:B:I18	B:B:L14	2.85	Yes	Yes	2	7	8
886	B:B:Q175	B:B:T173	2.83	No	No	0	4	5
887	R:R:Q213	R:R:T207	2.83	No	Yes	0	4	3
888	R:R:K383	R:R:L384	2.82	No	No	0	7	5
889	B:B:H183	B:B:S207	2.79	Yes	No	0	9	5
890	B:B:A104	B:B:R150	2.77	No	Yes	0	7	6
891	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
892	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
893	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
894	B:B:D303	B:B:K301	2.77	No	No	0	2	5
895	R:R:L154	R:R:L396	2.77	No	No	0	5	7
896	R:R:A158	R:R:F404	2.77	No	Yes	0	7	8
897	R:R:A375	R:R:R380	2.77	No	No	0	4	5
898	R:R:D222	R:R:L218	2.71	No	No	0	6	3
899	A:A:E27	A:A:K24	2.7	No	No	0	6	4
900	A:A:E50	A:A:K293	2.7	No	No	0	9	9
901	G:G:E17	G:G:K20	2.7	No	No	0	6	6
902	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
903	A:A:L63	A:A:Q59	2.66	No	Yes	0	9	9
904	G:G:L15	G:G:Q11	2.66	No	No	0	2	3
905	A:A:E299	A:A:L296	2.65	No	No	0	6	6
906	R:R:E138	R:R:L142	2.65	No	No	0	2	3
907	R:R:E418	R:R:L422	2.65	No	No	0	4	4
908	R:R:E292	R:R:N302	2.63	Yes	No	0	6	5
909	R:R:F369	R:R:V365	2.62	Yes	No	0	4	6
910	A:A:D33	A:A:Q29	2.61	No	No	0	5	4
911	A:A:E16	A:A:Q12	2.55	No	No	0	4	2
912	B:B:E12	B:B:Q13	2.55	No	No	0	4	1
913	A:A:I62	A:A:R61	2.51	No	No	0	9	8
914	R:R:I313	R:R:R310	2.51	No	Yes	0	7	6
915	R:R:F369	R:R:I317	2.51	Yes	No	0	4	7
916	R:R:T149	R:R:Y148	2.5	No	Yes	0	7	7
917	R:R:F385	R:R:L144	2.44	No	No	0	6	6
918	R:R:L307	R:R:R310	2.43	No	Yes	0	7	6
919	B:B:F292	B:B:N313	2.42	No	No	0	4	7
920	B:B:R46	B:B:R48	2.13	No	No	0	5	7
921	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
922	B:B:C317	B:B:G330	1.96	No	No	0	7	5
923	R:R:C296	R:R:G295	1.96	No	No	0	9	4
924	A:A:A48	A:A:G49	1.95	No	No	0	8	8
925	A:A:A226	A:A:G225	1.95	No	No	0	9	9
926	B:B:A140	B:B:G141	1.95	No	No	0	5	5
927	B:B:A309	B:B:G310	1.95	No	No	0	3	5
928	B:B:A106	B:B:P107	1.87	No	No	0	6	6
929	B:B:G77	B:B:S98	1.86	No	No	0	8	8
930	R:R:G395	R:R:S155	1.86	No	No	0	9	9
931	A:A:G52	A:A:T55	1.82	No	No	0	9	9
932	B:B:G131	B:B:T128	1.82	No	No	0	4	3
933	B:B:G182	B:B:T181	1.82	No	No	0	6	2
934	B:B:G224	B:B:T223	1.82	No	No	0	6	2
935	R:R:A158	R:R:A399	1.79	No	No	0	7	8
936	R:R:A162	R:R:A399	1.79	No	No	0	9	8
937	A:A:P326	A:A:T325	1.75	No	No	0	1	2
938	B:B:P107	B:B:T65	1.75	No	No	0	6	1
939	G:G:P53	G:G:T52	1.75	No	No	0	8	4
940	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
941	B:B:A28	G:G:S31	1.71	No	No	0	4	9
942	B:B:G77	B:B:L95	1.71	No	Yes	0	8	8
943	R:R:G168	R:R:L167	1.71	No	No	0	1	3
944	R:R:C226	R:R:V229	1.71	No	No	0	9	7
945	B:B:A11	G:G:V16	1.7	No	Yes	0	5	7
946	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
947	B:B:A309	B:B:V307	1.7	No	Yes	0	3	3
948	R:R:I308	R:R:P283	1.69	No	No	0	8	5
949	R:R:C296	R:R:T298	1.69	No	No	0	9	5
950	A:A:D354	A:A:G353	1.68	No	No	0	3	4
951	R:R:A153	R:R:T149	1.68	No	No	0	6	7
952	B:B:C271	B:B:I270	1.64	No	No	0	5	3
953	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
954	R:R:A200	R:R:I196	1.62	No	No	0	4	5
955	A:A:D331	A:A:P332	1.61	Yes	No	0	4	1
956	B:B:D38	B:B:P39	1.61	No	No	0	1	1
957	G:G:A10	G:G:K14	1.61	No	No	0	2	4
958	A:A:S349	A:A:T350	1.6	No	No	0	7	4
959	A:A:T40	A:A:V36	1.59	No	No	0	7	2
960	R:R:C236	R:R:L232	1.59	No	No	0	5	5
961	B:B:L4	G:G:A12	1.58	No	No	0	4	5
962	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
963	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
964	R:R:A368	R:R:L314	1.58	No	No	0	6	4
965	R:R:A375	R:R:L379	1.58	No	No	0	4	3
966	A:A:E309	A:A:P313	1.57	No	No	0	4	6
967	R:R:C174	R:R:N177	1.57	No	No	0	8	9
968	R:R:I188	R:R:V160	1.54	No	No	0	7	3
969	R:R:I196	R:R:V229	1.54	No	No	0	5	7
970	B:B:C25	B:B:Q259	1.53	No	No	0	3	6
971	R:R:K202	R:R:S206	1.53	No	No	0	4	4
972	R:R:K334	R:R:S333	1.53	Yes	No	0	9	7
973	B:B:A21	B:B:Q17	1.52	No	No	0	4	4
974	B:B:Q17	G:G:A23	1.52	No	No	0	4	8
975	R:R:F321	R:R:G318	1.51	No	No	0	6	4
976	R:R:F369	R:R:G318	1.51	Yes	No	0	4	4
977	A:A:G304	A:A:R333	1.5	No	No	0	5	5
978	A:A:L63	A:A:T369	1.47	No	No	0	9	9
979	A:A:D274	A:A:S275	1.47	Yes	No	0	5	8
980	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
981	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
982	G:G:A43	G:G:H44	1.46	No	No	0	4	6
983	A:A:D284	A:A:T285	1.45	No	No	0	4	7
984	R:R:D344	R:R:T343	1.45	No	No	0	7	5
985	A:A:F312	A:A:P313	1.44	No	No	0	8	6
986	A:A:Q262	A:A:T263	1.42	No	No	0	4	6
987	R:R:K202	R:R:L201	1.41	No	No	0	4	7
988	A:A:K58	A:A:N54	1.4	No	No	0	9	9
989	B:B:D118	B:B:I120	1.4	No	No	0	9	6
990	G:G:M21	G:G:N24	1.4	No	No	0	1	1
991	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
992	R:R:C329	R:R:R326	1.39	No	No	0	7	8
993	A:A:R385	R:R:A337	1.38	Yes	No	0	5	7
994	G:G:A10	G:G:R13	1.38	No	No	0	2	6
995	A:A:E327	A:A:K338	1.35	No	Yes	0	4	5
996	G:G:E17	G:G:K14	1.35	No	No	0	6	4
997	R:R:A209	R:R:Y205	1.33	No	No	0	1	3
998	A:A:E16	B:B:N88	1.31	No	Yes	0	4	7
999	A:A:R373	A:A:V214	1.31	No	No	0	5	6
1000	B:B:D5	B:B:Q6	1.31	No	No	0	1	1
1001	B:B:E172	B:B:N155	1.31	No	No	0	6	3
1002	R:R:A185	R:R:W274	1.3	No	Yes	0	3	9
1003	R:R:Q210	R:R:Q211	1.28	No	No	0	4	4
1004	R:R:Q210	R:R:Q213	1.28	No	No	0	4	4
1005	B:B:E12	B:B:Q9	1.27	No	No	0	4	3
1006	R:R:E423	R:R:H424	1.23	No	No	0	4	4
1007	R:R:L384	R:R:R380	1.21	No	No	0	5	5
1008	A:A:D331	A:A:R333	1.19	Yes	No	0	4	5
1009	B:B:D38	B:B:R283	1.19	No	Yes	0	1	9
1010	A:A:Q12	A:A:R13	1.17	No	No	0	2	4
1011	B:B:E138	B:B:R96	1.16	Yes	No	0	6	6
1012	R:R:M303	R:R:W306	1.16	No	No	0	5	6
1013	R:R:F381	R:R:R380	1.07	No	No	0	4	5
1014	R:R:R414	R:R:W417	1	No	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:K34	6.34	4	18	4
2	A:A:Q59	6.055	4	0	9
3	A:A:F219	7.67667	6	0	8
4	A:A:H220	9.8875	4	15	7
5	A:A:F222	9.7475	4	15	7
6	A:A:D223	5.1	4	0	9
7	A:A:K233	8.352	5	10	9
8	A:A:F238	10.6925	4	0	9
9	A:A:F273	10.454	5	16	9
10	A:A:D274	6.55	4	0	5
11	A:A:W277	10.545	4	16	6
12	A:A:W281	11.432	5	3	5
13	A:A:L282	6.705	4	0	9
14	A:A:F290	5.4675	4	7	9
15	A:A:N292	4.845	4	7	9
16	A:A:P321	6.655	4	0	5
17	A:A:E330	6.3825	4	0	3
18	A:A:D331	3.5175	4	0	4
19	A:A:V334	6.3625	4	0	4
20	A:A:K338	8.0325	4	0	5
21	A:A:Y339	6.824	5	12	3
22	A:A:F340	14.66	4	0	7
23	A:A:R342	7.34333	6	12	4
24	A:A:F345	11.125	4	0	8
25	A:A:Y360	9.555	6	8	8
26	A:A:F363	9.2875	4	12	5
27	A:A:T364	8.1425	4	7	9
28	A:A:D368	9.7	4	7	9
29	A:A:N371	7.98	5	7	9
30	A:A:R374	7.854	5	7	4
31	A:A:F376	7.2675	4	0	8
32	A:A:I383	4.1875	4	19	8
33	A:A:R385	10.8433	6	8	5
34	B:B:E10	5.645	4	2	8
35	B:B:L14	4.735	4	2	8
36	B:B:I18	5.32	5	2	7
37	B:B:R22	9.1175	4	2	6
38	B:B:L30	5.43	4	0	5
39	B:B:V40	5	4	1	3
40	B:B:L51	7.4625	4	0	9
41	B:B:H54	9.23167	6	6	9
42	B:B:K57	10.588	5	3	9
43	B:B:Y59	11.002	5	3	8
44	B:B:W63	9.7775	4	0	7
45	B:B:V71	5.29	4	11	8
46	B:B:L79	5.574	5	11	7
47	B:B:W82	12.256	5	6	9
48	B:B:Y85	11.5325	4	23	4
49	B:B:N88	7.22	4	6	7
50	B:B:K89	6.89833	6	6	9
51	B:B:I93	4.8825	4	0	7
52	B:B:L95	5.572	5	11	8
53	B:B:W99	10.044	5	0	9
54	B:B:M101	5.38	4	3	9
55	B:B:Y105	5.362	5	0	6
56	B:B:I123	5.53	4	0	6
57	B:B:Y124	6.466	5	11	6
58	B:B:E138	3.4625	4	0	6
59	B:B:H142	8.188	5	9	9
60	B:B:Y145	7.65	6	3	8
61	B:B:R150	6.4025	4	0	6
62	B:B:F151	5.588	5	0	9
63	B:B:L152	4.6675	4	25	3
64	B:B:T159	5.35667	6	9	9
65	B:B:L168	6.03	4	5	6
66	B:B:W169	12.256	5	9	8
67	B:B:F180	9.426	5	5	7
68	B:B:H183	8.13	6	5	9
69	B:B:D186	8.11	4	3	9
70	B:B:V187	5.145	4	5	9
71	B:B:F199	9.266	5	5	9
72	B:B:C204	5.7375	4	10	7
73	B:B:K209	12.3025	4	5	6
74	B:B:W211	9.47667	6	5	8
75	B:B:R219	6.64	4	26	5
76	B:B:Q220	10.28	4	2	7
77	B:B:H225	7.282	5	2	9
78	B:B:D228	7.336	5	10	9
79	B:B:I232	5.475	4	2	8
80	B:B:F234	7.1075	4	0	5
81	B:B:F235	7.31625	8	1	6
82	B:B:P236	6.7375	4	1	7
83	B:B:F241	8.062	5	2	6
84	B:B:T243	6.6575	4	2	8
85	B:B:D246	4.96	4	10	9
86	B:B:R251	10.47	5	2	8
87	B:B:F253	8.528	5	2	6
88	B:B:D254	5.2025	4	0	9
89	B:B:D258	13.2	4	2	7
90	B:B:Y264	5.58667	6	1	5
91	B:B:I269	4.7775	4	0	4
92	B:B:F278	5.63167	6	1	7
93	B:B:R283	5.82333	6	1	9
94	B:B:L284	5.4375	4	1	5
95	B:B:L285	4.214	5	1	6
96	B:B:Y289	9.38	6	1	7
97	B:B:D290	6.704	5	3	6
98	B:B:N295	9.824	5	1	6
99	B:B:V296	4.638	5	1	5
100	B:B:W297	7.296	5	1	8
101	B:B:R304	10.115	4	1	5
102	B:B:V307	3.788	5	1	3
103	B:B:L308	5.7575	4	0	7
104	B:B:H311	9.644	5	4	9
105	B:B:R314	12.922	5	3	8
106	B:B:W332	12.7571	7	3	9
107	B:B:D333	7.93	5	4	9
108	B:B:K337	9.81	4	4	6
109	B:B:W339	8.875	4	4	9
110	G:G:V16	4.475	4	2	7
111	G:G:R27	8.49	5	2	8
112	G:G:Y40	11.2325	4	1	6
113	G:G:D48	6.082	5	0	9
114	G:G:L51	4.012	5	0	6
115	G:G:N59	6.26	4	22	9
116	G:G:F61	7.3075	4	23	8
117	R:R:Y148	6.56286	7	13	7
118	R:R:Y152	5.658	5	13	7
119	R:R:L166	5.9075	4	27	8
120	R:R:F169	12.0525	4	4	7
121	R:R:R176	6.3475	4	0	9
122	R:R:F184	5.622	5	27	8
123	R:R:F187	8.052	5	17	8
124	R:R:R190	7.0775	4	0	8
125	R:R:T207	4.065	4	0	3
126	R:R:R227	12.08	4	29	8
127	R:R:F230	8.05	4	28	5
128	R:R:Q234	6.79	4	28	7
129	R:R:Y242	6.50667	6	30	6
130	R:R:W243	10.75	7	14	9
131	R:R:L244	5.2575	4	17	9
132	R:R:E247	8.7525	4	0	9
133	R:R:Y250	6.58	5	0	8
134	R:R:F266	5.6	4	0	6
135	R:R:W274	9.754	5	14	9
136	R:R:W284	6.9825	4	28	8
137	R:R:E292	5.06	4	0	6
138	R:R:Y305	9.0025	4	31	4
139	R:R:R310	6.61	4	0	6
140	R:R:F324	6.9125	4	32	9
141	R:R:K334	6.836	5	8	9
142	R:R:L360	4.735	4	0	9
143	R:R:F369	2.8775	4	0	4
144	R:R:F404	3.625	4	0	8
145	R:R:E412	12.022	5	4	8
146	R:R:K415	7.81	4	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:H54	B:B:S74	25.8121	16.74	Yes	No	0	9	9
2	B:B:D76	B:B:S74	26.0028	10.31	No	No	0	9	9
3	B:B:H54	B:B:W82	21.4046	6.35	Yes	Yes	6	9	9
4	B:B:D76	B:B:L55	27.5951	12.21	No	No	0	9	6
5	A:A:K34	B:B:L55	94.452	8.46	Yes	No	0	4	6
6	A:A:K34	R:R:E262	93.0094	5.4	Yes	No	18	4	6
7	A:A:Y37	B:B:L55	98.2291	5.86	No	No	0	4	6
8	A:A:R42	A:A:Y37	98.4979	18.52	No	No	0	9	4
9	A:A:F222	A:A:R42	98.6412	4.28	Yes	No	0	7	9
10	R:R:E262	R:R:T175	92.9009	9.88	No	No	0	6	7
11	R:R:T175	R:R:Y250	42.5693	7.49	No	Yes	0	7	8
12	R:R:L254	R:R:Y250	20.0915	9.38	No	Yes	0	8	8
13	A:A:H387	R:R:L254	19.8114	23.14	No	No	0	8	8
14	A:A:H387	A:A:I383	18.9503	3.98	No	Yes	19	8	8
15	A:A:H41	A:A:I383	18.4175	5.3	No	Yes	0	6	8
16	A:A:F219	A:A:H41	17.8627	10.18	Yes	No	0	8	6
17	A:A:F222	B:B:W99	100	22.05	Yes	Yes	0	7	9
18	A:A:F238	B:B:W99	31.1879	8.02	Yes	Yes	0	9	9
19	A:A:F238	A:A:L44	30.2829	25.58	Yes	No	0	9	9
20	A:A:L44	A:A:L46	28.1746	5.54	No	No	0	9	8
21	A:A:F212	A:A:F219	14.5159	13.93	No	Yes	0	9	8
22	A:A:F212	A:A:M60	13.9585	6.22	No	No	0	9	9
23	A:A:F246	A:A:L46	27.9573	4.87	No	No	0	9	8
24	B:B:Q75	B:B:W99	82.3828	6.57	No	Yes	0	9	9
25	B:B:Q75	B:B:Y59	54.7174	20.29	No	Yes	3	9	8
26	B:B:M101	B:B:Y59	50.5978	5.99	Yes	Yes	3	9	8
27	B:B:M101	B:B:Y145	50.4599	7.18	Yes	Yes	3	9	8
28	A:A:W234	B:B:Y145	11.3566	5.79	No	Yes	3	9	8
29	A:A:F246	A:A:L272	11.1324	6.09	No	No	0	9	8
30	A:A:L272	A:A:R231	11.1285	12.15	No	No	0	8	9
31	A:A:R231	A:A:W234	11.2222	7	No	No	0	9	9
32	A:A:D240	B:B:W99	27.7759	4.47	No	Yes	0	6	9
33	A:A:D240	B:B:K57	27.7729	6.91	No	Yes	0	6	9
34	B:B:K57	B:B:W332	55.0621	20.89	Yes	Yes	3	9	9
35	A:A:W281	B:B:W332	33.6217	10.31	Yes	Yes	3	5	9
36	B:B:K57	B:B:Q75	27.7258	6.78	Yes	No	3	9	9
37	B:B:W332	B:B:Y59	51.0173	13.5	Yes	Yes	3	9	8
38	B:B:R314	B:B:W332	34.4928	25.99	Yes	Yes	3	8	9
39	A:A:F246	A:A:F273	37.5021	9.65	No	Yes	0	9	9
40	A:A:F273	A:A:F345	30.4038	17.15	Yes	Yes	0	9	8
41	A:A:F363	A:A:K338	11.4477	18.61	Yes	Yes	0	5	5
42	A:A:F363	A:A:L291	13.7363	4.87	Yes	No	0	5	8
43	A:A:L289	A:A:L291	14.1169	8.3	No	No	0	9	8
44	A:A:F345	A:A:L289	25.4776	4.87	Yes	No	0	8	9
45	A:A:L289	A:A:P361	10.9799	4.93	No	No	0	9	5
46	A:A:P361	A:A:R342	10.2083	5.76	No	Yes	12	5	4
47	A:A:W281	B:B:D290	31.4833	10.05	Yes	Yes	3	5	6
48	B:B:D290	B:B:R314	31.5744	7.15	Yes	Yes	3	6	8
49	A:A:Y391	R:R:Y250	10.9283	4.96	No	Yes	0	4	8
50	A:A:Y391	R:R:L251	10.6387	10.55	No	No	0	4	9
51	R:R:L251	R:R:V327	10.3529	7.45	No	No	0	9	9
52	R:R:L255	R:R:V327	10.0867	4.47	No	No	0	8	9
53	R:R:F266	R:R:T175	62.1662	3.89	Yes	No	0	6	7
54	R:R:F266	R:R:I179	55.691	5.02	Yes	No	0	6	8
55	R:R:E247	R:R:I179	52.7388	5.47	Yes	No	0	9	8
56	R:R:E247	R:R:L359	23.9642	11.93	Yes	No	0	9	9
57	R:R:L359	R:R:L360	22.8993	4.15	No	Yes	0	9	9
58	B:B:G162	B:B:Y145	47.2428	8.69	No	Yes	3	9	8
59	B:B:G162	B:B:S161	47.2712	3.71	No	No	0	9	9
60	B:B:H142	B:B:S161	46.4084	12.55	Yes	No	0	9	9
61	B:B:H142	B:B:T159	44.9979	5.48	Yes	Yes	9	9	9
62	B:B:C149	B:B:T159	39.0032	3.38	No	Yes	9	8	9
63	B:B:C149	B:B:T102	38.8792	6.76	No	No	0	8	8
64	B:B:C148	B:B:T102	38.7233	3.38	No	No	0	6	8
65	B:B:C148	B:B:L190	38.7714	4.76	No	No	0	6	5
66	B:B:L190	B:B:S160	38.6119	7.51	No	No	0	5	6
67	B:B:S160	B:B:V187	38.452	4.85	No	Yes	0	6	9
68	B:B:C166	B:B:V187	31.1376	5.12	No	Yes	5	8	9
69	B:B:C166	B:B:F180	27.8747	5.59	No	Yes	5	8	7
70	B:B:F180	B:B:G216	26.6542	3.01	Yes	No	0	7	4
71	B:B:E215	B:B:G216	26.4758	3.27	No	No	0	3	4
72	B:B:D212	B:B:E215	13.0486	5.2	No	No	0	9	3
73	B:B:D212	B:B:R219	12.6576	13.1	No	Yes	26	9	5
74	B:B:L210	B:B:R219	24.954	3.64	No	Yes	0	5	5
75	B:B:L210	B:B:Q220	24.1691	5.32	No	Yes	0	5	7
76	B:B:E215	B:B:M217	13.2493	9.47	No	No	0	3	3
77	B:B:M217	B:B:R219	12.6792	4.96	No	Yes	0	3	5
78	B:B:R68	B:B:Y85	18.4379	16.46	No	Yes	0	5	4
79	B:B:D323	B:B:M325	10.2781	5.54	No	No	0	7	5
80	B:B:M325	G:G:P49	11.3486	5.03	No	No	0	5	7
81	G:G:D48	G:G:P49	13.5728	4.83	Yes	No	0	9	7
82	B:B:L284	B:B:V296	12.8113	5.96	Yes	Yes	1	5	5
83	B:B:L308	B:B:V296	24.6516	4.47	Yes	Yes	0	7	5
84	B:B:L308	B:B:W339	21.281	7.97	Yes	Yes	0	7	9
85	B:B:K337	B:B:W339	11.0462	8.12	Yes	Yes	4	6	9
86	B:B:N313	B:B:W332	39.8472	5.65	No	Yes	0	7	9
87	B:B:D333	B:B:N313	39.3295	4.04	Yes	No	0	9	7
88	B:B:L51	B:B:W82	17.9942	17.08	Yes	Yes	0	9	9
89	B:B:I338	B:B:L51	16.9806	4.28	No	Yes	0	5	9
90	B:B:D66	B:B:R68	18.0366	3.57	No	No	0	8	5
91	B:B:D66	B:B:L69	17.8243	9.5	No	No	0	8	5
92	B:B:L69	B:B:Y105	17.6117	7.03	No	Yes	0	5	6
93	B:B:V71	B:B:Y105	16.0719	5.05	Yes	Yes	0	8	6
94	B:B:L79	B:B:V71	14.2896	4.47	Yes	Yes	11	7	8
95	B:B:Y85	G:G:F61	13.8178	9.28	Yes	Yes	23	4	8
96	B:B:F222	B:B:Q220	13.0397	16.4	No	Yes	2	8	7
97	B:B:F278	B:B:L285	15.9388	6.09	Yes	Yes	1	7	6
98	B:B:L285	B:B:W297	18.2956	4.56	Yes	Yes	1	6	8
99	B:B:W297	B:B:Y289	38.8149	9.65	Yes	Yes	1	8	7
100	B:B:C271	B:B:D290	60.586	4.67	No	Yes	0	5	6
101	B:B:C271	B:B:D291	59.1811	9.34	No	No	0	5	8
102	B:B:D291	B:B:Y289	47.0619	9.2	No	Yes	0	8	7
103	B:B:L252	B:B:Y264	10.226	7.03	No	Yes	0	7	5
104	B:B:C294	B:B:L308	10.5896	6.35	No	Yes	0	5	7
105	B:B:D291	B:B:N293	11.4323	10.77	No	No	0	8	5
106	B:B:C294	B:B:V315	11.108	5.12	No	No	0	5	7
107	B:B:D333	B:B:H311	34.1232	8.82	Yes	Yes	4	9	9
108	B:B:T329	B:B:W339	10.7561	12.13	No	Yes	0	8	9
109	B:B:D312	B:B:D333	10.4131	9.31	No	Yes	4	5	9
110	R:R:E247	R:R:L183	29.9145	5.3	Yes	No	0	9	9
111	R:R:F187	R:R:L183	17.2619	6.09	Yes	No	17	8	9
112	R:R:F187	R:R:N240	12.0292	16.92	Yes	No	17	8	9
113	R:R:N240	R:R:R190	23.3077	12.05	No	Yes	0	9	8
114	R:R:R190	R:R:Y152	11.4393	5.14	Yes	Yes	0	8	7
115	R:R:L183	R:R:L244	12.3889	5.54	No	Yes	17	9	9
116	R:R:L244	R:R:N240	11.8398	5.49	Yes	No	17	9	9
117	R:R:L360	R:R:N320	19.9239	4.12	Yes	No	0	9	9
118	R:R:L245	R:R:N320	19.6465	5.49	No	No	0	8	9
119	R:R:L245	R:R:Y242	19.3688	4.69	No	Yes	0	8	6
120	R:R:F280	R:R:Y242	17.1251	10.32	No	Yes	30	5	6
121	R:R:F280	R:R:I309	16.8542	6.28	No	No	0	5	7
122	R:R:I309	R:R:Q234	16.5731	8.23	No	Yes	0	7	7
123	R:R:R190	R:R:Y241	10.8708	7.2	Yes	No	0	8	8
124	R:R:Q234	R:R:W284	11.962	5.48	Yes	Yes	28	7	8
125	R:R:K288	R:R:W284	10.8753	13.92	No	Yes	0	8	8
126	B:B:I338	G:G:F61	16.7431	5.02	No	Yes	0	5	8
127	B:B:H311	B:B:V315	11.3862	5.54	Yes	No	0	9	7
128	B:B:H311	B:B:T329	11.0333	8.21	Yes	No	0	9	8
129	B:B:H311	B:B:K337	11.7563	13.1	Yes	Yes	4	9	6
130	B:B:W297	B:B:Y264	20.3066	6.75	Yes	Yes	1	8	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:C347	W:W:?1	36.37	0	No	No	7	0	1	0
R:R:A350	W:W:?1	8.33	0	No	No	8	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
50.00	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
50.00	Single	7DUR	PubChem 156022738	7DUR-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
33.33	Single	7E14	PubChem 156022738	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
11.11	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
11.11	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
10.00	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
9.09	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
9.09	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/&β;1/&γ;2
8.33	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
8.33	Single	6QZH	HY-133073; Na	6QZH-CCR7-HY-133073; Na
8.33	Consensus	ccr7_off_allo	Other Ligand	6QZH-CCR7-HY-133073; Na
7.69	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
7.14	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
6.67	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
6.25	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
5.88	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
5.26	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2

PDB Summary
PDB	7EVM
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GLP-1
Species	Homo sapiens
Ligand	-
Other Ligand(s)	PubChem 156022738
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	2.5
Date	2021-08-11
D.O.I.	10.1038/s41467-021-24058-z

Net Summary
I_min	3.89
Number of Linked Nodes	868
Number of Links	1014
Number of Hubs	146
Number of Links mediated by Hubs	554
Number of Communities	32
Number of Nodes involved in Communities	205
Number of Links involved in Communities	279

Path Summary
Number Of Nodes in MetaPath	131
Number Of Links MetaPath	130
Number of Shortest Paths	1167928
Length Of Smallest Path	3
Average Path Length	26.7454
Length of Longest Path	65
Minimum Path Strength	1.14
Average Path Strength	8.31037
Maximum Path Strength	23.44
Minimum Path Correlation	0.71
Average Path Correlation	0.978349
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	47.7715
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.5994
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	HNO
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	HNO
Name	N-tert-butyl-6,7-bis(chloranyl)quinoxalin-2-amine
Synonyms
Identifier	~{N}-~{tert}-butyl-6,7-bis(chloranyl)quinoxalin-2-amine
Formula	C12 H13 Cl2 N3
Molecular Weight	270.158
SMILES	CC(C)(C)Nc1cnc2cc(c(cc2n1)Cl)Cl
PubChem	156022738
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	0
Total Bonds	31
Total Aromatic Bonds	11


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>7EVM_Chain_A D Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A G E S G K N T I V K Q M R I L H I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V A S S S Y N Q T N R L Q A A L K L F D S I W N N K W L R D T S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N I R R V F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>7EVM_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>7EVM_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>7EVM_Chain_R S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L S C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S V L S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F V R V I C I V V S K L K A N L T D I K C R L A K S T L T L I P L L G T H E V I F A F V A R G T L R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L E H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/&β;1/&γ;2	4.1	2017-05-24	10.1038/nature22394
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/&β;1/&γ;2	3.3	2018-02-21	10.1038/nature25773
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/&β;1/&γ;2	3	2020-01-08	10.1038/s41586-019-1902-z
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/&β;1/&γ;2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2020-11-18	10.1073/pnas.2014879117
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/&β;1/&γ;2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/&β;1/&γ;2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/&β;1/&γ;2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/&β;1/&γ;2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/&β;1/&γ;2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/&β;1/&γ;2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/&β;1/&γ;2	3	2022-03-02	10.1038/s41467-022-28683-0
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/&β;1/&γ;2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/&β;1/&γ;2	3.09	2022-06-29	10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.46	2023-11-08	10.1073/pnas.2303696120
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.54	2024-03-06	10.1038/s41421-024-00649-0

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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