psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:A25	R:R:G24	1.95	No	No	0	4	5
2	R:R:A25	R:R:P26	1.87	No	No	0	4	6
3	R:R:F31	R:R:Q27	8.2	No	No	0	4	5
4	R:R:V28	R:R:Y202	7.57	No	Yes	0	3	1
5	R:R:L32	R:R:M29	4.24	No	No	2	4	5
6	R:R:M29	R:R:Y202	2.39	No	Yes	2	5	1
7	R:R:L32	R:R:P86	3.28	No	Yes	2	4	3
8	R:R:L32	R:R:Y202	3.52	No	Yes	2	4	1
9	R:R:E34	R:R:F33	3.5	No	No	0	2	4
10	R:R:F33	R:R:W36	4.01	No	Yes	0	4	6
11	R:R:F62	R:R:W36	5.01	Yes	Yes	0	7	6
12	R:R:K64	R:R:W36	2.32	No	Yes	0	4	6
13	R:R:W36	R:R:Y84	9.65	Yes	Yes	0	6	5
14	R:R:D41	R:R:K37	11.06	No	No	0	4	3
15	R:R:L38	R:R:W83	2.28	No	Yes	0	3	2
16	R:R:F62	R:R:Y39	4.13	Yes	Yes	2	7	6
17	R:R:S66	R:R:Y39	2.54	Yes	Yes	2	5	6
18	R:R:C67	R:R:Y39	4.03	Yes	Yes	2	9	6
19	R:R:P82	R:R:Y39	5.56	Yes	Yes	2	8	6
20	R:R:W83	R:R:Y39	16.4	Yes	Yes	2	2	6
21	R:R:Y39	R:R:Y84	8.94	Yes	Yes	2	6	5
22	H:H:?7	R:R:Y39	7.32	Yes	Yes	2	0	6
23	R:R:C43	R:R:G40	1.96	Yes	No	2	9	4
24	R:R:F62	R:R:G40	6.02	Yes	No	2	7	4
25	R:R:Q42	R:R:W83	6.57	No	Yes	2	5	2
26	H:H:?7	R:R:Q42	15.43	Yes	No	2	0	5
27	H:H:?8	R:R:Q42	5.94	No	No	2	0	5
28	R:R:C43	R:R:L47	3.17	Yes	No	2	9	5
29	R:R:C43	R:R:F62	8.38	Yes	Yes	2	9	7
30	R:R:C43	R:R:C67	7.28	Yes	Yes	2	9	9
31	R:R:F62	R:R:H44	3.39	Yes	No	0	7	2
32	H:H:?7	R:R:N46	31.85	Yes	No	0	0	5
33	R:R:L47	R:R:R60	8.5	No	Yes	2	5	4
34	R:R:C67	R:R:L47	4.76	Yes	No	2	9	5
35	R:R:L50	R:R:P51	4.93	No	No	0	3	2
36	R:R:L50	R:R:R60	2.43	No	Yes	0	3	4
37	R:R:P51	R:R:P52	1.95	No	No	0	2	1
38	R:R:P52	R:R:P53	1.95	No	Yes	0	1	3
39	R:R:P53	R:R:V57	3.53	Yes	No	2	3	3
40	R:R:P53	R:R:R60	2.88	Yes	Yes	2	3	4
41	R:R:D70	R:R:P53	8.05	No	Yes	2	4	3
42	H:H:?12	R:R:P53	2.93	No	Yes	0	0	3
43	R:R:E55	R:R:V57	5.7	No	No	0	4	3
44	R:R:E55	R:R:P72	4.72	No	No	0	4	1
45	R:R:G104	R:R:L56	1.71	No	No	0	9	2
46	R:R:D70	R:R:V57	5.84	No	No	2	4	3
47	R:R:C100	R:R:C58	7.28	Yes	No	2	9	9
48	R:R:C58	R:R:G104	1.96	No	No	0	9	9
49	R:R:C58	R:R:W106	15.67	No	Yes	2	9	9
50	H:H:?12	R:R:N59	25.72	No	No	0	0	4
51	R:R:D70	R:R:R60	17.87	No	Yes	2	4	4
52	R:R:T61	R:R:W106	3.64	No	Yes	0	6	9
53	R:R:D63	R:R:Y65	2.3	Yes	Yes	2	9	6
54	R:R:D63	R:R:W68	10.05	Yes	Yes	2	9	9
55	R:R:D63	R:R:K98	9.68	Yes	Yes	2	9	8
56	R:R:D63	R:R:P114	6.44	Yes	No	0	9	5
57	R:R:D63	R:R:R116	10.72	Yes	Yes	2	9	6
58	R:R:S66	R:R:Y65	6.36	Yes	Yes	2	5	6
59	R:R:P82	R:R:Y65	9.74	Yes	Yes	2	8	6
60	R:R:Y65	R:R:Y84	3.97	Yes	Yes	2	6	5
61	R:R:L85	R:R:Y65	2.34	Yes	Yes	2	6	6
62	R:R:V96	R:R:Y65	3.79	Yes	Yes	2	7	6
63	R:R:R116	R:R:Y65	12.35	Yes	Yes	2	6	6
64	R:R:A118	R:R:Y65	5.34	No	Yes	2	5	6
65	R:R:C121	R:R:Y65	4.03	Yes	Yes	2	9	6
66	R:R:S66	R:R:W68	3.71	Yes	Yes	2	5	9
67	R:R:I79	R:R:S66	3.1	No	Yes	2	4	5
68	R:R:P82	R:R:S66	5.34	Yes	Yes	2	8	5
69	R:R:S66	R:R:V96	3.23	Yes	Yes	2	5	7
70	H:H:?7	R:R:C67	2.83	Yes	Yes	2	0	9
71	R:R:P69	R:R:W68	2.7	No	Yes	0	6	9
72	R:R:A77	R:R:W68	2.59	No	Yes	2	7	9
73	R:R:I79	R:R:W68	8.22	No	Yes	2	4	9
74	R:R:V96	R:R:W68	4.9	Yes	Yes	2	7	9
75	R:R:K98	R:R:W68	19.73	Yes	Yes	2	8	9
76	R:R:W106	R:R:W68	2.81	Yes	Yes	2	9	9
77	R:R:P69	R:R:T71	1.75	No	Yes	0	6	7
78	R:R:P72	R:R:T71	5.25	No	Yes	2	1	7
79	R:R:T71	R:R:T75	3.14	Yes	No	2	7	5
80	R:R:A77	R:R:T71	5.03	No	Yes	2	7	7
81	R:R:C100	R:R:T71	5.07	Yes	Yes	2	9	7
82	R:R:T71	R:R:W106	7.28	Yes	Yes	2	7	9
83	R:R:P72	R:R:T75	6.99	No	No	2	1	5
84	R:R:A73	R:R:C100	1.81	No	Yes	0	6	9
85	R:R:A73	R:R:G104	1.95	No	No	0	6	9
86	R:R:N74	R:R:P102	4.89	No	No	0	7	1
87	H:H:?13	R:R:N74	22.05	No	No	0	0	7
88	R:R:F97	R:R:T76	3.89	Yes	No	0	5	5
89	R:R:R99	R:R:T76	10.35	No	No	0	3	5
90	R:R:A77	R:R:W106	2.59	No	Yes	2	7	9
91	R:R:F97	R:R:N78	4.83	Yes	No	6	5	4
92	H:H:?9	R:R:N78	25.72	No	No	6	0	4
93	R:R:F95	R:R:S80	5.28	No	No	0	1	3
94	R:R:C81	R:R:P82	1.88	No	Yes	0	9	8
95	R:R:C81	R:R:V91	5.12	No	Yes	0	9	6
96	R:R:C121	R:R:C81	7.28	Yes	No	0	9	9
97	R:R:P82	R:R:Y84	9.74	Yes	Yes	2	8	5
98	R:R:L85	R:R:P82	4.93	Yes	Yes	2	6	8
99	R:R:W83	R:R:Y84	1.93	Yes	Yes	2	2	5
100	R:R:H88	R:R:W83	5.29	No	Yes	2	4	2
101	H:H:?8	R:R:W83	2.03	No	Yes	2	0	2
102	R:R:L85	R:R:Y84	4.69	Yes	Yes	2	6	5
103	R:R:L85	R:R:P86	3.28	Yes	Yes	2	6	3
104	R:R:L85	R:R:W87	5.69	Yes	Yes	2	6	3
105	R:R:P86	R:R:W87	10.81	Yes	Yes	2	3	3
106	R:R:P86	R:R:Y202	11.13	Yes	Yes	2	3	1
107	R:R:V91	R:R:W87	4.9	Yes	Yes	0	6	3
108	R:R:M123	R:R:W87	12.8	Yes	Yes	2	3	3
109	R:R:W215	R:R:W87	13.12	No	Yes	2	2	3
110	R:R:H88	R:R:H89	5.97	No	No	2	4	5
111	R:R:H88	R:R:Q92	7.42	No	No	2	4	1
112	R:R:H89	R:R:Q92	3.71	No	No	2	5	1
113	R:R:D218	R:R:K90	5.53	No	No	0	4	4
114	R:R:R94	R:R:V91	2.62	No	Yes	0	5	6
115	R:R:H93	R:R:R94	9.03	No	No	0	4	5
116	R:R:Q120	R:R:R94	22.2	No	No	0	5	5
117	R:R:F95	R:R:F97	2.14	No	Yes	0	1	5
118	R:R:R116	R:R:V96	3.92	Yes	Yes	2	6	7
119	R:R:A118	R:R:V96	3.39	No	Yes	2	5	7
120	R:R:C121	R:R:V96	1.71	Yes	Yes	2	9	7
121	R:R:D117	R:R:F97	2.39	No	Yes	0	7	5
122	R:R:F97	R:R:Q120	3.51	Yes	No	0	5	5
123	H:H:?9	R:R:F97	6.52	No	Yes	6	0	5
124	R:R:K98	R:R:W106	22.05	Yes	Yes	2	8	9
125	R:R:K98	R:R:R116	2.48	Yes	Yes	2	8	6
126	R:R:R99	R:R:V107	3.92	No	No	0	3	5
127	R:R:C100	R:R:W106	2.61	Yes	Yes	2	9	9
128	R:R:G101	R:R:P102	4.06	No	No	0	5	1
129	R:R:G101	R:R:V107	1.84	No	No	0	5	5
130	R:R:D103	R:R:P102	4.83	No	No	0	5	1
131	R:R:G112	R:R:R108	6	No	No	0	6	1
132	R:R:G109	R:R:P110	4.06	No	No	7	4	3
133	R:R:G109	R:R:Q113	3.29	No	Yes	7	4	4
134	R:R:G109	R:R:W115	2.81	No	No	0	4	4
135	R:R:P110	R:R:Q113	4.74	No	Yes	7	3	4
136	R:R:Q113	R:R:R111	4.67	Yes	No	0	4	4
137	R:R:P114	R:R:Q113	3.16	No	Yes	0	5	4
138	R:R:D117	R:R:S119	8.83	No	No	0	7	5
139	R:R:A118	R:R:C121	3.61	No	Yes	2	5	9
140	R:R:G125	R:R:M123	1.75	No	Yes	0	2	3
141	R:R:M123	R:R:S213	3.07	Yes	No	0	3	3
142	R:R:M123	R:R:W215	2.33	Yes	No	2	3	2
143	R:R:D124	R:R:W215	2.23	No	No	0	2	2
144	R:R:G125	R:R:T214	3.64	No	Yes	0	2	1
145	R:R:E126	R:R:T214	2.82	No	Yes	0	3	1
146	R:R:E127	R:R:Q204	5.1	No	No	4	1	4
147	R:R:E127	R:R:I206	2.73	No	Yes	4	1	4
148	R:R:E127	R:R:S211	8.62	No	No	4	1	4
149	R:R:I128	R:R:T214	3.04	No	Yes	0	2	1
150	R:R:E129	R:R:I206	4.1	No	Yes	0	1	4
151	R:R:D209	R:R:E129	9.09	No	No	0	4	1
152	R:R:A135	R:R:V130	1.7	No	No	0	3	1
153	R:R:Q131	R:R:V134	4.3	No	No	0	3	2
154	R:R:D209	R:R:Q131	3.92	No	No	0	4	3
155	R:R:E133	R:R:K132	5.4	No	No	0	2	2
156	R:R:V134	R:R:Y138	2.52	No	No	0	2	5
157	R:R:A135	R:R:L210	3.15	No	No	0	3	4
158	R:R:F141	R:R:M137	11.2	Yes	No	8	6	4
159	R:R:M137	R:R:S379	4.6	No	No	0	4	3
160	R:R:F383	R:R:M137	8.71	No	No	8	5	4
161	R:R:F383	R:R:Y138	2.06	No	No	0	5	5
162	R:R:F141	R:R:S140	5.28	Yes	No	0	6	4
163	R:R:F141	R:R:M144	2.49	Yes	No	0	6	6
164	R:R:F141	R:R:F383	33.22	Yes	No	8	6	5
165	R:R:D195	R:R:Q142	5.22	No	No	0	7	5
166	R:R:Q142	R:R:R199	4.67	No	No	0	5	4
167	R:R:F387	R:R:M144	7.46	No	No	0	5	6
168	R:R:Y145	R:R:Y149	5.96	No	Yes	3	7	8
169	R:R:V191	R:R:Y145	5.05	No	No	3	7	7
170	R:R:L386	R:R:Y145	8.21	No	No	0	7	7
171	R:R:G148	R:R:S390	3.71	No	Yes	3	7	9
172	R:R:F391	R:R:G148	7.53	No	No	3	7	7
173	R:R:K187	R:R:Y149	10.75	Yes	Yes	0	8	8
174	R:R:A188	R:R:Y149	5.34	No	Yes	0	8	8
175	R:R:V191	R:R:Y149	5.05	No	Yes	3	7	8
176	R:R:S390	R:R:Y149	5.09	Yes	Yes	3	9	8
177	R:R:L192	R:R:S150	4.5	No	No	0	7	7
178	R:R:G393	R:R:S152	3.71	No	No	0	9	9
179	R:R:L394	R:R:S152	3	Yes	No	0	5	9
180	R:R:G154	R:R:L153	1.71	No	No	0	4	6
181	R:R:A155	R:R:L394	4.73	No	Yes	0	6	5
182	R:R:A155	R:R:A397	1.79	No	No	0	6	8
183	R:R:F181	R:R:L156	4.87	Yes	Yes	0	8	8
184	R:R:L156	R:R:V185	4.47	Yes	No	0	8	8
185	R:R:G393	R:R:L156	1.71	No	Yes	0	9	8
186	R:R:A397	R:R:L156	3.15	No	Yes	0	8	8
187	R:R:I162	R:R:L158	4.28	No	No	1	8	5
188	R:R:F402	R:R:L158	6.09	Yes	No	1	9	5
189	R:R:A159	R:R:F181	2.77	No	Yes	1	9	8
190	R:R:A159	R:R:C401	3.61	No	Yes	1	9	9
191	R:R:A159	R:R:F402	2.77	No	Yes	1	9	9
192	R:R:F181	R:R:L160	2.44	Yes	No	0	8	6
193	R:R:C401	R:R:I162	3.27	Yes	No	1	9	8
194	R:R:F402	R:R:I162	3.77	Yes	No	1	9	8
195	R:R:G164	R:R:L163	1.71	No	No	0	3	8
196	R:R:L163	R:R:N174	5.49	No	No	0	8	9
197	R:R:C401	R:R:L163	3.17	Yes	No	0	9	8
198	R:R:G164	R:R:G165	2.11	No	No	0	3	3
199	R:R:E410	R:R:S167	2.87	No	No	10	8	8
200	R:R:R413	R:R:S167	3.95	No	No	10	7	8
201	R:R:C171	R:R:K168	9.7	No	No	9	7	8
202	R:R:K168	R:R:N174	12.59	No	No	9	8	9
203	R:R:H170	R:R:L169	11.57	No	No	0	7	9
204	R:R:C171	R:R:N174	9.45	No	No	9	7	9
205	R:R:R261	R:R:T172	7.76	No	No	0	5	7
206	R:R:R173	R:R:Y248	8.23	Yes	Yes	1	9	8
207	R:R:R173	R:R:Y343	5.14	Yes	Yes	1	9	7
208	R:R:L347	R:R:R173	4.86	Yes	Yes	1	9	9
209	R:R:N404	R:R:R173	6.03	No	Yes	0	9	9
210	R:R:E406	R:R:R173	13.96	No	Yes	1	9	9
211	R:R:I176	R:R:W241	2.35	Yes	Yes	1	9	9
212	R:R:I176	R:R:V244	4.61	Yes	Yes	1	9	8
213	R:R:E245	R:R:I176	8.2	Yes	Yes	1	9	9
214	R:R:I176	R:R:Y248	8.46	Yes	Yes	1	9	8
215	R:R:I176	R:R:L268	4.28	Yes	Yes	1	9	5
216	R:R:F181	R:R:H177	2.26	Yes	Yes	1	8	9
217	R:R:E245	R:R:H177	12.31	Yes	Yes	1	9	9
218	R:R:H177	R:R:L347	2.57	Yes	Yes	1	9	9
219	R:R:H177	R:R:Y400	20.69	Yes	Yes	1	9	8
220	R:R:N179	R:R:W241	12.43	No	Yes	1	8	9
221	R:R:N179	R:R:W272	9.04	No	Yes	1	8	9
222	R:R:F181	R:R:L180	4.87	Yes	Yes	1	8	9
223	R:R:F184	R:R:L180	3.65	Yes	Yes	1	8	9
224	R:R:L180	R:R:W241	2.28	Yes	Yes	1	9	9
225	R:R:L180	R:R:L242	2.77	Yes	No	0	9	9
226	R:R:E245	R:R:L180	3.98	Yes	Yes	1	9	9
227	R:R:L180	R:R:V396	2.98	Yes	Yes	1	9	9
228	R:R:L180	R:R:Y400	2.34	Yes	Yes	1	9	8
229	R:R:F181	R:R:V396	3.93	Yes	Yes	1	8	9
230	R:R:F181	R:R:Y400	3.09	Yes	Yes	1	8	8
231	R:R:C401	R:R:F181	2.79	Yes	Yes	1	9	8
232	R:R:A182	R:R:W272	2.59	No	Yes	0	4	9
233	R:R:F184	R:R:S183	3.96	Yes	Yes	1	8	9
234	R:R:A237	R:R:S183	1.71	Yes	Yes	1	7	9
235	R:R:N238	R:R:S183	7.45	Yes	Yes	1	9	9
236	R:R:S183	R:R:W272	2.47	Yes	Yes	1	9	9
237	R:R:F184	R:R:N238	22.96	Yes	Yes	1	8	9
238	R:R:F184	R:R:Q392	2.34	Yes	Yes	1	8	9
239	R:R:F184	R:R:G393	4.52	Yes	No	0	8	9
240	R:R:F184	R:R:V396	2.62	Yes	Yes	1	8	9
241	R:R:F230	R:R:L186	2.44	No	No	0	4	7
242	R:R:I235	R:R:K187	4.36	Yes	Yes	0	5	8
243	R:R:K187	R:R:N238	5.6	Yes	Yes	0	8	9
244	R:R:K187	R:R:Q392	2.71	Yes	Yes	0	8	9
245	R:R:F230	R:R:S190	2.64	No	No	0	4	5
246	R:R:M231	R:R:S190	4.6	No	No	0	6	5
247	R:R:L197	R:R:V193	2.98	No	No	0	4	5
248	R:R:A227	R:R:V193	3.39	No	No	0	6	5
249	R:R:A227	R:R:I194	3.25	No	No	0	6	6
250	R:R:G196	R:R:R199	3	No	No	0	3	4
251	R:R:G223	R:R:L197	1.71	No	No	0	3	4
252	R:R:C224	R:R:L197	3.17	No	No	0	9	4
253	R:R:L198	R:R:R201	10.93	No	No	0	6	4
254	R:R:C294	R:R:L198	3.17	No	No	0	9	6
255	R:R:R201	R:R:V212	5.23	No	No	0	4	3
256	R:R:L216	R:R:R201	3.64	Yes	No	0	2	4
257	R:R:S213	R:R:Y202	5.09	No	Yes	0	3	1
258	R:R:S203	R:R:V212	4.85	No	No	0	4	3
259	R:R:I206	R:R:Q204	8.23	Yes	No	4	4	4
260	R:R:K205	R:R:L210	4.23	No	No	0	4	4
261	R:R:I206	R:R:S211	6.19	Yes	No	4	4	4
262	R:R:Q293	R:R:T214	4.25	No	Yes	0	4	1
263	R:R:A220	R:R:L216	4.73	No	Yes	0	6	2
264	R:R:A220	R:R:S217	1.71	No	No	0	6	4
265	R:R:R225	R:R:V221	3.92	Yes	No	0	8	4
266	R:R:A222	R:R:G223	1.95	No	No	0	4	3
267	R:R:C224	R:R:C294	7.28	No	No	0	9	9
268	R:R:C287	R:R:R225	4.18	No	Yes	5	3	8
269	R:R:N291	R:R:R225	12.05	No	Yes	5	6	8
270	R:R:R225	R:R:W295	15.99	Yes	Yes	5	8	9
271	R:R:F230	R:R:V226	2.62	No	No	0	4	4
272	R:R:V229	R:R:W295	2.45	No	Yes	0	6	9
273	R:R:M231	R:R:Q232	5.44	No	Yes	11	6	7
274	R:R:I235	R:R:M231	2.92	Yes	No	11	5	6
275	R:R:I235	R:R:Q232	4.12	Yes	Yes	11	5	7
276	R:R:L307	R:R:Q232	7.99	No	Yes	0	7	7
277	R:R:W272	R:R:Y233	4.82	Yes	No	0	9	9
278	R:R:P275	R:R:Y233	2.78	Yes	No	0	9	9
279	R:R:M276	R:R:Y233	8.38	No	No	0	3	9
280	R:R:A237	R:R:G234	1.95	Yes	No	0	7	5
281	R:R:I235	R:R:R308	2.51	Yes	No	0	5	6
282	R:R:C240	R:R:V236	1.71	Yes	Yes	1	6	6
283	R:R:P275	R:R:V236	7.07	Yes	Yes	1	9	6
284	R:R:V236	R:R:V279	3.21	Yes	Yes	0	6	6
285	R:R:P310	R:R:V236	1.77	No	Yes	1	9	6
286	R:R:A237	R:R:W272	2.59	Yes	Yes	1	7	9
287	R:R:A237	R:R:P275	1.87	Yes	Yes	1	7	9
288	R:R:N238	R:R:Y239	2.33	Yes	Yes	0	9	8
289	R:R:V311	R:R:Y239	7.57	No	Yes	0	8	8
290	R:R:I315	R:R:Y239	4.84	Yes	Yes	0	7	8
291	R:R:L358	R:R:Y239	10.55	No	Yes	0	9	8
292	R:R:E362	R:R:Y239	6.73	No	Yes	0	8	8
293	R:R:C240	R:R:G271	1.96	Yes	No	0	6	9
294	R:R:A274	R:R:C240	1.81	No	Yes	1	4	6
295	R:R:C240	R:R:P275	7.53	Yes	Yes	1	6	9
296	R:R:V244	R:R:W241	7.36	Yes	Yes	1	8	9
297	R:R:L268	R:R:W241	6.83	Yes	Yes	1	5	9
298	R:R:G271	R:R:W241	8.44	No	Yes	0	9	9
299	R:R:W241	R:R:W272	21.56	Yes	Yes	1	9	9
300	R:R:L242	R:R:L354	5.54	No	Yes	0	9	9
301	R:R:I355	R:R:L242	4.28	Yes	No	0	8	9
302	R:R:I317	R:R:L243	2.85	No	No	0	6	8
303	R:R:L243	R:R:N318	10.98	No	No	0	8	9
304	R:R:F264	R:R:V244	6.55	Yes	Yes	1	6	8
305	R:R:L268	R:R:V244	11.92	Yes	Yes	1	5	8
306	R:R:E245	R:R:T351	2.82	Yes	Yes	1	9	9
307	R:R:E245	R:R:Y400	17.96	Yes	Yes	1	9	8
308	R:R:G246	R:R:N318	1.7	No	No	1	9	9
309	R:R:G246	R:R:T351	1.82	No	Yes	1	9	9
310	R:R:G246	R:R:I355	1.76	No	Yes	1	9	8
311	R:R:I321	R:R:L247	2.85	No	No	0	8	7
312	R:R:L252	R:R:Y248	7.03	Yes	Yes	1	8	8
313	R:R:E260	R:R:Y248	7.86	No	Yes	1	6	8
314	R:R:F264	R:R:Y248	7.22	Yes	Yes	1	6	8
315	R:R:L347	R:R:Y248	2.34	Yes	Yes	1	9	8
316	R:R:L249	R:R:L347	4.15	No	Yes	0	9	9
317	R:R:L249	R:R:T351	5.9	No	Yes	0	9	9
318	R:R:H250	R:R:R324	2.26	No	No	0	7	8
319	R:R:H250	R:R:I325	2.65	No	No	0	7	9
320	R:R:H250	R:R:L328	2.57	No	No	0	7	8
321	R:R:L252	R:R:N251	2.75	Yes	No	1	8	7
322	R:R:F263	R:R:N251	7.25	Yes	No	1	5	7
323	R:R:E260	R:R:L252	11.93	No	Yes	1	6	8
324	R:R:F263	R:R:L252	2.44	Yes	Yes	1	5	8
325	R:R:F264	R:R:L252	3.65	Yes	Yes	1	6	8
326	R:R:K332	R:R:L253	7.05	No	No	0	9	8
327	R:R:G254	R:R:L328	5.13	No	No	0	6	8
328	R:R:R261	R:R:S262	2.64	No	No	0	5	5
329	R:R:F263	R:R:F264	5.36	Yes	Yes	1	5	6
330	R:R:F263	R:R:Y267	7.22	Yes	No	0	5	7
331	R:R:F264	R:R:L268	18.27	Yes	Yes	1	6	5
332	R:R:L266	R:R:Y267	5.86	No	No	0	3	7
333	R:R:A274	R:R:I270	3.25	No	No	0	4	7
334	R:R:G273	R:R:P275	2.03	No	Yes	0	6	9
335	R:R:G273	R:R:M276	1.75	No	No	0	6	3
336	R:R:A274	R:R:P275	1.87	No	Yes	1	4	9
337	R:R:M276	R:R:V280	6.09	No	No	0	3	2
338	R:R:F278	R:R:F309	2.14	No	No	1	5	4
339	R:R:F278	R:R:P310	15.89	No	No	1	5	9
340	R:R:A283	R:R:V279	1.7	No	Yes	0	5	6
341	R:R:L307	R:R:V279	4.47	No	Yes	0	7	6
342	R:R:P281	R:R:V280	3.53	No	No	0	4	2
343	R:R:P281	R:R:W282	4.05	No	No	0	4	9
344	R:R:I306	R:R:W282	16.44	No	No	0	8	9
345	R:R:L288	R:R:V284	2.98	No	No	0	1	4
346	R:R:G302	R:R:K286	3.49	No	No	0	2	8
347	R:R:C287	R:R:L288	3.17	No	No	0	3	1
348	R:R:C287	R:R:W295	11.75	No	Yes	5	3	9
349	R:R:E290	R:R:S297	7.19	No	No	0	6	4
350	R:R:D299	R:R:E290	9.09	No	No	0	4	6
351	R:R:N291	R:R:W295	5.65	No	Yes	5	6	9
352	R:R:V292	R:R:W295	3.68	No	Yes	0	4	9
353	R:R:S297	R:R:V292	3.23	No	No	0	4	4
354	R:R:H372	R:R:N298	14.03	No	No	0	4	6
355	R:R:D370	R:R:N300	4.04	No	No	0	4	5
356	R:R:G302	R:R:I306	3.53	No	No	0	2	8
357	R:R:W304	R:R:W305	2.81	No	No	0	6	7
358	R:R:F312	R:R:W304	3.01	No	No	0	5	6
359	R:R:I306	R:R:L307	4.28	No	No	0	8	7
360	R:R:R308	R:R:V311	10.46	No	No	0	6	8
361	R:R:E362	R:R:R308	3.49	No	No	0	8	6
362	R:R:F309	R:R:P310	5.78	No	No	1	4	9
363	R:R:F309	R:R:L313	4.87	No	No	0	4	3
364	R:R:F312	R:R:V363	3.93	No	No	0	5	6
365	R:R:F319	R:R:I315	2.51	No	Yes	0	7	7
366	R:R:G359	R:R:I315	5.29	No	Yes	0	9	7
367	R:R:I315	R:R:V363	3.07	Yes	No	0	7	6
368	R:R:I317	R:R:I321	2.94	No	No	0	6	8
369	R:R:I355	R:R:N318	8.5	Yes	No	1	8	9
370	R:R:F320	R:R:R324	5.34	No	No	0	5	8
371	R:R:I321	R:R:I325	2.94	No	No	0	8	9
372	R:R:F322	R:R:L352	3.65	No	No	0	9	8
373	R:R:F322	R:R:P356	7.22	No	No	0	9	9
374	R:R:Q327	R:R:R324	7.01	No	No	0	8	8
375	R:R:I325	R:R:L352	4.28	No	No	0	9	8
376	R:R:F345	R:R:L329	4.87	Yes	No	0	7	9
377	R:R:K332	R:R:Q337	8.14	No	No	0	9	7
378	R:R:K332	R:R:M338	2.88	No	No	0	9	5
379	R:R:L333	R:R:M338	4.24	Yes	No	1	7	5
380	R:R:F345	R:R:L333	2.44	Yes	Yes	1	7	7
381	R:R:Q337	R:R:R336	5.84	No	No	0	7	5
382	R:R:F345	R:R:M338	2.49	Yes	No	1	7	5
383	R:R:H339	R:R:H340	4.78	No	No	0	4	5
384	R:R:D342	R:R:Y343	4.6	No	Yes	1	7	7
385	R:R:D342	R:R:K344	6.91	No	No	1	7	6
386	R:R:K344	R:R:Y343	10.75	No	Yes	1	6	7
387	R:R:R346	R:R:Y343	4.12	Yes	Yes	1	8	7
388	R:R:E406	R:R:Y343	3.37	No	Yes	1	9	7
389	R:R:F345	R:R:K349	6.2	Yes	No	1	7	9
390	R:R:F345	W:W:?3	9.12	Yes	Yes	1	7	0
391	R:R:K405	R:R:R346	16.09	No	Yes	0	6	8
392	R:R:E406	R:R:R346	4.65	No	Yes	1	9	8
393	R:R:R346	W:W:?3	3.31	Yes	Yes	1	8	0
394	R:R:L347	R:R:Y400	2.34	Yes	Yes	1	9	8
395	R:R:L347	W:W:?3	1.88	Yes	Yes	1	9	0
396	R:R:A348	R:R:L352	3.15	No	No	0	7	8
397	R:R:K349	W:W:?3	25.91	No	Yes	1	9	0
398	R:R:L399	R:R:S350	3	No	No	1	8	9
399	R:R:S350	R:R:Y400	7.63	No	Yes	1	9	8
400	R:R:S350	W:W:?3	11.24	No	Yes	1	9	0
401	R:R:T351	R:R:Y400	7.49	Yes	Yes	1	9	8
402	R:R:T353	W:W:?3	20.06	No	Yes	0	8	0
403	R:R:L354	R:R:L358	2.77	Yes	No	0	9	9
404	R:R:L354	R:R:V396	4.47	Yes	Yes	0	9	9
405	R:R:L354	R:R:Y400	4.69	Yes	Yes	0	9	8
406	R:R:I355	R:R:P356	3.39	Yes	No	0	8	9
407	R:R:L357	W:W:?3	2.83	No	Yes	0	9	0
408	R:R:L358	R:R:Q392	7.99	No	Yes	0	9	9
409	R:R:V360	R:R:V364	3.21	No	No	0	6	6
410	R:R:E362	R:R:H361	3.69	No	Yes	0	8	8
411	R:R:D385	R:R:H361	10.08	No	Yes	0	7	8
412	R:R:H361	R:R:L388	7.71	Yes	No	0	8	6
413	R:R:H361	R:R:S389	5.58	Yes	No	1	8	6
414	R:R:H361	R:R:Q392	2.47	Yes	Yes	1	8	9
415	R:R:D385	R:R:F365	7.17	No	No	0	7	7
416	R:R:F367	R:R:V368	11.8	No	No	0	5	5
417	R:R:E371	R:R:Q374	6.37	No	Yes	0	5	4
418	R:R:H372	R:R:R378	3.39	No	No	0	4	4
419	R:R:G375	R:R:Q374	3.29	No	Yes	0	2	4
420	R:R:L377	R:R:Q374	5.32	No	Yes	0	3	4
421	R:R:Q374	R:R:R378	2.34	Yes	No	0	4	4
422	R:R:L382	R:R:R378	3.64	No	No	0	5	4
423	R:R:L382	R:R:L386	2.77	No	No	0	5	7
424	R:R:F387	R:R:S390	2.64	No	Yes	3	5	9
425	R:R:F387	R:R:F391	10.72	No	No	3	5	7
426	R:R:Q392	R:R:S389	2.89	Yes	No	1	9	6
427	R:R:F391	R:R:S390	3.96	No	Yes	3	7	9
428	R:R:L394	R:R:V398	2.98	Yes	No	0	5	6
429	R:R:L395	W:W:?3	1.88	No	Yes	0	6	0
430	R:R:A397	R:R:F402	2.77	No	Yes	0	8	9
431	R:R:L403	R:R:V398	2.98	No	No	0	5	6
432	R:R:L399	R:R:L403	2.77	No	No	1	8	5
433	R:R:L399	W:W:?3	11.3	No	Yes	1	8	0
434	R:R:L403	W:W:?3	2.83	No	Yes	1	5	0
435	R:R:N404	R:R:V407	5.91	No	No	0	9	9
436	R:R:N404	W:W:?3	9.34	No	Yes	0	9	0
437	R:R:Q408	R:R:R412	5.84	No	No	0	7	5
438	R:R:E410	R:R:R413	20.93	No	No	10	8	7
439	R:R:R419	R:R:W418	47.98	No	No	0	5	3
440	H:H:?7	H:H:?8	36.34	Yes	No	2	0	0
441	H:H:?10	H:H:?9	42.95	No	No	0	0	0
442	R:R:G112	R:R:Q113	1.64	No	Yes	0	6	4
443	R:R:A228	R:R:I194	1.62	No	No	0	5	6
444	R:R:V130	R:R:V134	1.6	No	No	0	1	2
445	R:R:V229	R:R:V279	1.6	No	Yes	0	6	6
446	R:R:V363	R:R:V364	1.6	No	No	0	6	6
447	R:R:A188	R:R:L153	1.58	No	No	0	8	6
448	R:R:A178	R:R:L160	1.58	No	No	0	7	6
449	R:R:I128	R:R:V130	1.54	No	No	0	2	1
450	R:R:K90	R:R:V91	1.52	No	Yes	0	4	6
451	R:R:A335	R:R:Q337	1.52	No	No	0	7	7
452	R:R:K405	R:R:T341	1.5	No	No	0	6	6
453	R:R:L157	R:R:V185	1.49	No	No	0	3	8
454	R:R:L210	R:R:V212	1.49	No	No	0	4	3
455	R:R:L216	R:R:V221	1.49	Yes	No	0	2	4
456	R:R:L216	R:R:T200	1.47	Yes	No	0	2	3
457	R:R:L377	R:R:T376	1.47	No	No	0	3	2
458	R:R:D195	R:R:V191	1.46	No	No	0	7	7
459	R:R:D195	R:R:T146	1.45	No	No	0	7	7
460	R:R:K286	R:R:M301	1.44	No	No	0	8	5
461	R:R:E55	R:R:T54	1.41	No	No	0	4	1
462	R:R:E260	R:R:T172	1.41	No	No	0	6	7
463	R:R:K381	R:R:L377	1.41	No	No	0	7	3
464	R:R:L49	R:R:L50	1.38	No	No	0	2	3
465	R:R:L151	R:R:L394	1.38	No	Yes	0	5	5
466	R:R:L313	R:R:L316	1.38	No	No	0	3	3
467	R:R:L255	R:R:N251	1.37	No	No	0	5	7
468	R:R:A314	R:R:Y239	1.33	No	Yes	0	8	8
469	R:R:D103	R:R:Q105	1.31	No	No	0	5	5
470	R:R:H340	R:R:L333	1.29	No	Yes	0	5	7
471	R:R:D370	R:R:H372	1.26	No	No	0	4	4
472	R:R:F289	R:R:L288	1.22	No	No	0	3	1
473	R:R:L333	R:R:R334	1.21	Yes	No	0	7	7
474	R:R:K35	R:R:Y84	1.19	No	Yes	0	4	5
475	R:R:L192	R:R:Y149	1.17	No	Yes	0	7	8
476	R:R:F303	R:R:Q232	1.17	No	Yes	0	4	7
477	R:R:K37	R:R:W36	1.16	No	Yes	0	3	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:W36	4.43	5	0	6
2	R:R:Y39	6.98857	7	2	6
3	R:R:C43	5.1975	4	2	9
4	R:R:P53	3.868	5	2	3
5	R:R:R60	7.92	4	2	4
6	R:R:F62	5.386	5	2	7
7	R:R:D63	7.838	5	2	9
8	R:R:Y65	5.58	9	2	6
9	R:R:S66	4.04667	6	2	5
10	R:R:C67	4.725	4	2	9
11	R:R:W68	6.83875	8	2	9
12	R:R:T71	4.58667	6	2	7
13	R:R:P82	6.19833	6	2	8
14	R:R:W83	5.75	6	2	2
15	R:R:Y84	5.73	7	2	5
16	R:R:L85	4.186	5	2	6
17	R:R:P86	7.125	4	2	3
18	R:R:W87	9.464	5	2	3
19	R:R:V91	3.54	4	0	6
20	R:R:V96	3.49	6	2	7
21	R:R:F97	3.88	6	6	5
22	R:R:K98	13.485	4	2	8
23	R:R:C100	4.1925	4	2	9
24	R:R:W106	8.09286	7	2	9
25	R:R:Q113	3.5	5	7	4
26	R:R:R116	7.3675	4	2	6
27	R:R:C121	4.1575	4	2	9
28	R:R:M123	4.9875	4	2	3
29	R:R:F141	13.0475	4	8	6
30	R:R:Y149	5.56	6	3	8
31	R:R:L156	3.55	4	0	8
32	R:R:R173	7.644	5	1	9
33	R:R:I176	5.58	5	1	9
34	R:R:H177	9.4575	4	1	9
35	R:R:L180	3.26714	7	1	9
36	R:R:F181	3.3775	8	1	8
37	R:R:S183	3.8975	4	1	9
38	R:R:F184	6.675	6	1	8
39	R:R:K187	5.855	4	0	8
40	R:R:Y202	5.94	5	2	1
41	R:R:I206	5.3125	4	4	4
42	R:R:T214	3.4375	4	0	1
43	R:R:L216	2.8325	4	0	2
44	R:R:R225	9.035	4	5	8
45	R:R:Q232	4.68	4	11	7
46	R:R:I235	3.4775	4	11	5
47	R:R:V236	3.44	4	1	6
48	R:R:A237	2.03	4	1	7
49	R:R:N238	9.585	4	1	9
50	R:R:Y239	5.55833	6	0	8
51	R:R:C240	3.2525	4	1	6
52	R:R:W241	8.75	7	1	9
53	R:R:V244	7.61	4	1	8
54	R:R:E245	9.054	5	1	9
55	R:R:Y248	6.85667	6	1	8
56	R:R:L252	5.56	5	1	8
57	R:R:F263	5.5675	4	1	5
58	R:R:F264	8.21	5	1	6
59	R:R:L268	10.325	4	1	5
60	R:R:W272	7.17833	6	1	9
61	R:R:P275	3.85833	6	1	9
62	R:R:V279	2.745	4	0	6
63	R:R:W295	7.904	5	5	9
64	R:R:I315	3.9275	4	0	7
65	R:R:L333	2.295	4	1	7
66	R:R:Y343	5.596	5	1	7
67	R:R:F345	5.024	5	1	7
68	R:R:R346	7.0425	4	1	8
69	R:R:L347	3.02333	6	1	9
70	R:R:T351	4.5075	4	1	9
71	R:R:L354	4.3675	4	0	9
72	R:R:I355	4.4825	4	1	8
73	R:R:H361	5.906	5	1	8
74	R:R:Q374	4.33	4	0	4
75	R:R:S390	3.85	4	3	9
76	R:R:Q392	3.68	5	1	9
77	R:R:L394	3.0225	4	0	5
78	R:R:V396	3.5	4	1	9
79	R:R:Y400	8.27875	8	1	8
80	R:R:C401	3.21	4	1	9
81	R:R:F402	3.85	4	1	9
82	W:W:?3	9.06364	11	1	0
83	H:H:?7	18.754	5	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L85	R:R:Y84	16.7994	4.69	Yes	Yes	2	6	5
2	R:R:L85	R:R:P82	20.3201	4.93	Yes	Yes	2	6	8
3	R:R:S66	R:R:Y65	11.4898	6.36	Yes	Yes	2	5	6
4	R:R:L85	R:R:Y65	48.6908	2.34	Yes	Yes	2	6	6
5	R:R:P82	R:R:S66	11.7462	5.34	Yes	Yes	2	8	5
6	R:R:C67	R:R:Y39	12.411	4.03	Yes	Yes	2	9	6
7	R:R:C67	R:R:L47	10.6601	4.76	Yes	No	2	9	5
8	R:R:E55	R:R:P72	12.293	4.72	No	No	0	4	1
9	R:R:P72	R:R:T71	18.3463	5.25	No	Yes	2	1	7
10	R:R:P69	R:R:W68	10.4423	2.7	No	Yes	0	6	9
11	R:R:D63	R:R:W68	10.8584	10.05	Yes	Yes	2	9	9
12	R:R:D63	R:R:Y65	20.5992	2.3	Yes	Yes	2	9	6
13	R:R:A77	R:R:W68	10.4391	2.59	No	Yes	2	7	9
14	R:R:T71	R:R:W106	13.0197	7.28	Yes	Yes	2	7	9
15	R:R:W106	R:R:W68	20.8941	2.81	Yes	Yes	2	9	9
16	R:R:K98	R:R:W106	10.2049	22.05	Yes	Yes	2	8	9
17	R:R:S66	R:R:W68	21.9542	3.71	Yes	Yes	2	5	9
18	R:R:V96	R:R:W68	10.9418	4.9	Yes	Yes	2	7	9
19	R:R:V96	R:R:Y65	10.9133	3.79	Yes	Yes	2	7	6
20	R:R:R94	R:R:V91	10.311	2.62	No	Yes	0	5	6
21	R:R:V91	R:R:W87	10.7372	4.9	Yes	Yes	0	6	3
22	R:R:G125	R:R:M123	98.7498	1.75	No	Yes	0	2	3
23	R:R:G125	R:R:T214	99.0024	3.64	No	Yes	0	2	1
24	R:R:V130	R:R:V134	91.2833	1.6	No	No	0	1	2
25	R:R:I128	R:R:V130	100	1.54	No	No	0	2	1
26	R:R:I128	R:R:T214	99.7525	3.04	No	Yes	0	2	1
27	R:R:A135	R:R:V130	10.532	1.7	No	No	0	3	1
28	R:R:V134	R:R:Y138	92.7583	2.52	No	No	0	2	5
29	R:R:A135	R:R:L210	10.1708	3.15	No	No	0	3	4
30	R:R:F141	R:R:F383	92.7773	33.22	Yes	No	8	6	5
31	R:R:F383	R:R:Y138	92.9515	2.06	No	No	0	5	5
32	R:R:F141	R:R:M144	93.9302	2.49	Yes	No	0	6	6
33	R:R:S390	R:R:Y149	94.7599	5.09	Yes	Yes	3	9	8
34	R:R:F387	R:R:S390	93.9744	2.64	No	Yes	3	5	9
35	R:R:F387	R:R:M144	94.131	7.46	No	No	0	5	6
36	R:R:K187	R:R:Y149	99.9148	10.75	Yes	Yes	0	8	8
37	R:R:F184	R:R:N238	36.2538	22.96	Yes	Yes	1	8	9
38	R:R:K187	R:R:N238	46.3324	5.6	Yes	Yes	0	8	9
39	R:R:F184	R:R:Q392	36.4534	2.34	Yes	Yes	1	8	9
40	R:R:K187	R:R:Q392	54.9841	2.71	Yes	Yes	0	8	9
41	R:R:F184	R:R:L180	60.1642	3.65	Yes	Yes	1	8	9
42	R:R:I176	R:R:Y248	10.0635	8.46	Yes	Yes	1	9	8
43	R:R:L180	R:R:W241	16.6163	2.28	Yes	Yes	1	9	9
44	R:R:L347	R:R:Y400	27.2953	2.34	Yes	Yes	1	9	8
45	R:R:L180	R:R:Y400	31.0491	2.34	Yes	Yes	1	9	8
46	R:R:L354	R:R:Y400	15.731	4.69	Yes	Yes	0	9	8
47	R:R:L354	R:R:L358	19.3894	2.77	Yes	No	0	9	9
48	R:R:L358	R:R:Q392	18.3028	7.99	No	Yes	0	9	9
49	R:R:L347	W:W:?3	18.0445	1.88	Yes	Yes	1	9	0
50	R:R:S350	W:W:?3	16.0638	11.24	No	Yes	1	9	0
51	R:R:S350	R:R:Y400	18.1986	7.63	No	Yes	1	9	8
52	R:R:R201	R:R:V212	10.1026	5.23	No	No	0	4	3
53	R:R:L210	R:R:V212	10.0698	1.49	No	No	0	4	3
54	R:R:L216	R:R:R201	10.5541	3.64	Yes	No	0	2	4
55	R:R:R225	R:R:V221	10.7296	3.92	Yes	No	0	8	4
56	R:R:L216	R:R:V221	10.6955	1.49	Yes	No	0	2	4
57	R:R:V229	R:R:W295	11.0605	2.45	No	Yes	0	6	9
58	R:R:V229	R:R:V279	11.087	1.6	No	Yes	0	6	6
59	R:R:I355	R:R:L242	13.4232	4.28	Yes	No	0	8	9
60	R:R:F345	W:W:?3	18.0401	9.12	Yes	Yes	1	7	0
61	R:R:M123	R:R:W87	95.7923	12.8	Yes	Yes	2	3	3
62	R:R:L85	R:R:W87	85.1972	5.69	Yes	Yes	2	6	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:R173	R:R:Y248	8.23	1	Yes	Yes	9	8	2	2
R:R:R173	R:R:Y343	5.14	1	Yes	Yes	9	7	2	2
R:R:L347	R:R:R173	4.86	1	Yes	Yes	9	9	1	2
R:R:N404	R:R:R173	6.03	0	No	Yes	9	9	1	2
R:R:E406	R:R:R173	13.96	1	No	Yes	9	9	2	2
R:R:H177	R:R:L347	2.57	1	Yes	Yes	9	9	2	1
R:R:H177	R:R:Y400	20.69	1	Yes	Yes	9	8	2	2
R:R:L347	R:R:Y248	2.34	1	Yes	Yes	9	8	1	2
R:R:L249	R:R:L347	4.15	0	No	Yes	9	9	2	1
R:R:F345	R:R:L329	4.87	1	Yes	No	7	9	1	2
R:R:L333	R:R:M338	4.24	1	Yes	No	7	5	2	2
R:R:F345	R:R:L333	2.44	1	Yes	Yes	7	7	1	2
R:R:F345	R:R:M338	2.49	1	Yes	No	7	5	1	2
R:R:R346	R:R:Y343	4.12	1	Yes	Yes	8	7	1	2
R:R:E406	R:R:Y343	3.37	1	No	Yes	9	7	2	2
R:R:F345	R:R:K349	6.2	1	Yes	No	7	9	1	1
R:R:F345	W:W:?3	9.12	1	Yes	Yes	7	0	1	0
R:R:K405	R:R:R346	16.09	0	No	Yes	6	8	2	1
R:R:E406	R:R:R346	4.65	1	No	Yes	9	8	2	1
R:R:R346	W:W:?3	3.31	1	Yes	Yes	8	0	1	0
R:R:L347	R:R:Y400	2.34	1	Yes	Yes	9	8	1	2
R:R:L347	W:W:?3	1.88	1	Yes	Yes	9	0	1	0
R:R:K349	W:W:?3	25.91	1	No	Yes	9	0	1	0
R:R:L399	R:R:S350	3	1	No	No	8	9	1	1
R:R:S350	R:R:Y400	7.63	1	No	Yes	9	8	1	2
R:R:S350	W:W:?3	11.24	1	No	Yes	9	0	1	0
R:R:T353	W:W:?3	20.06	0	No	Yes	8	0	1	0
R:R:L357	W:W:?3	2.83	0	No	Yes	9	0	1	0
R:R:L395	W:W:?3	1.88	0	No	Yes	6	0	1	0
R:R:L403	R:R:V398	2.98	1	No	No	5	6	1	2
R:R:L399	R:R:L403	2.77	1	No	No	8	5	1	1
R:R:L399	W:W:?3	11.3	1	No	Yes	8	0	1	0
R:R:L403	W:W:?3	2.83	1	No	Yes	5	0	1	0
R:R:N404	R:R:V407	5.91	0	No	No	9	9	1	2
R:R:N404	W:W:?3	9.34	0	No	Yes	9	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
64.29	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
61.54	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
60.00	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
58.33	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
58.33	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
53.85	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
30.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
26.67	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
26.09	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
25.00	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
25.00	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
23.53	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
21.74	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
21.43	Single	7EB2	rac-BHFF	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
21.43	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
21.43	Consensus	gabab_on	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
21.43	Consensus	gi_class-c	Other Ligand	gi_mglu gi_gaba
21.05	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/&β;1/&γ;2
20.00	Consensus	gi_gaba	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
19.05	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
17.39	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
15.79	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
15.79	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
15.38	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
15.38	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
15.38	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
11.76	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
11.11	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
11.11	Consensus	nts1_on_allo	Other Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
9.52	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
9.52	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
9.09	Single	7DUR	PubChem 156022738	7DUR-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
9.09	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
8.70	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
8.70	Consensus	ccr9_off_allo	Other Ligand	5LWE-CCR9-Vercirnon
8.33	Single	7E14	PubChem 156022738	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
8.33	Single	7EVM	PubChem 156022738	7EVM-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
6.67	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
5.88	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
5.56	Single	7LD3	PubChem 25263603	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
5.56	Consensus	a1_on_allo	Other Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
5.26	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.76	Single	7RBT	PubChem 163183774	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Consensus	ffa3_on_allo	Other Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
4.35	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
3.12	Single	3VG9	Antibody	3VG9-A_2A-ZM241385-Antibody
2.94	Single	3VGA	Antibody	3VGA-A_2A-ZM241385-Antibody

PDB Summary
PDB	5XEZ
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	Glucagon
Species	Homo sapiens
Ligand	-
Other Ligand(s)	NNC0640
Protein Partners	-
PDB Resolution	3
Date	2017-05-24
D.O.I.	10.1038/nature22363

Net Summary
I_min	1.7
Number of Linked Nodes	364
Number of Links	477
Number of Hubs	83
Number of Links mediated by Hubs	301
Number of Communities	11
Number of Nodes involved in Communities	133
Number of Links involved in Communities	214

Path Summary
Number Of Nodes in MetaPath	63
Number Of Links MetaPath	62
Number of Shortest Paths	244070
Length Of Smallest Path	3
Average Path Length	21.2922
Length of Longest Path	38
Minimum Path Strength	1.25
Average Path Strength	5.67608
Maximum Path Strength	34.335
Minimum Path Correlation	0.7
Average Path Correlation	0.964748
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	64.534
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	56.7674
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	97V
PDB Residues	W:W:?3
Environment Details	Open EMBL-EBI Page
Code	97V
Name	4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide
Synonyms
Identifier	4-[[(4-cyclohexylphenyl)-[(3-methylsulfonylphenyl)carbamoyl]amino]methyl]-~{N}-(1~{H}-1,2,3,4-tetrazol-5-yl)benzamide
Formula	C29 H31 N7 O4 S
Molecular Weight	573.666
SMILES	CS(=O)(=O)c1cccc(c1)NC(=O)N(Cc2ccc(cc2)C(=O)Nc3[nH]nnn3)c4ccc(cc4)C5CCCCC5
PubChem	23549991
Formal Charge	0
Total Atoms	72
Total Chiral Atoms	0
Total Bonds	76
Total Aromatic Bonds	23


Code	NAG
PDB Residues	H:H:?7 H:H:?8 H:H:?9 H:H:?10 H:H:?12 H:H:?13
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetyl-D-glucosamine
Identifier	N-[(2R,3R,4R,5S,6R)-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl]ethanamide
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES	CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P47871
Sequence	>5XEZ_Chain_R G A P Q V M D F L F E K W K L Y G D Q C H H N L S L L P P P T E L V C N R T F D K Y S C W P D T P A N T T A N I S C P W Y L P W H H K V Q H R F V F K R C G P D G Q W V R G P R G Q P W R D A S Q C Q M D G E E I E V Q K E V A K M Y S S F Q V M Y T V G Y S L S L G A L L L A L A I L G G L S K L H C T R N A I H A N L F A S F V L K A S S V L V I D G L L R T R Y S Q K I G D D L S V S T W L S D G A V A G C R V A A V F M Q Y G I V A N Y C W L L V E G L Y L H N L L G L A E R S F F S L Y L G I G W G A P M L F V V P W A V V K C L F E N V Q C W T S N D N M G F W W I L R F P V F L A I L I N F F I F V R I V Q L L V A K L R A R Q M H H T D Y K F R L A K S T L T L I P L L G V H E V V F A F V T D E H A Q G T L R S A K L F F D L F L S S F Q G L L V A V L Y C F L N K E V Q S E L R R R W H R W R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7CZ5	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-	Gs/&β;1/&γ;2	2.6	2020-11-18	10.1038/s41467-020-18945-0
	7V9L	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.6	2022-04-06	10.1073/pnas.2106606118
	7V9M	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-	Gs/&β;1/&γ;2	3.29	2021-10-20	10.1073/pnas.2106606118
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/&β;1/&γ;2	2.98	2021-08-04	10.7554/eLife.68719
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/&β;1/&γ;2	3.1	2022-02-23	10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.24	2022-04-13	10.1073/pnas.2116506119
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774	chim(NtGi1-Gs)/&β;1/&γ;2	3.08	2022-04-13	10.1073/pnas.2116506119
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-03-02	10.1038/s41467-022-28683-0
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.23	2023-10-18	10.1073/pnas.2306145120
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.13	2023-10-18	10.1073/pnas.2306145120
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.86	2024-03-06	10.1038/s41421-024-00649-0
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/&β;1/&γ;2	4.1	2017-05-24	10.1038/nature22394
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/&β;1/&γ;2	3.3	2018-02-21	10.1038/nature25773
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/&β;1/&γ;2	3	2020-01-08	10.1038/s41586-019-1902-z
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/&β;1/&γ;2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2020-11-18	10.1073/pnas.2014879117
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/&β;1/&γ;2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/&β;1/&γ;2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/&β;1/&γ;2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/&β;1/&γ;2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/&β;1/&γ;2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/&β;1/&γ;2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/&β;1/&γ;2	3	2022-03-02	10.1038/s41467-022-28683-0
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/&β;1/&γ;2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/&β;1/&γ;2	3.09	2022-06-29	10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.46	2023-11-08	10.1073/pnas.2303696120
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	7D68	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-	Gs/&β;1/&γ;2	3	2020-12-16	10.1038/s41422-020-00442-0
	4L6R	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	-	3.3	2013-07-24	10.1038/nature12393
	5EE7	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	MK0893	-	2.5	2016-04-20	10.1038/nature17414
	5XEZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3	2017-05-24	10.1038/nature22363
	5XF1	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3.19	2017-05-24	10.1038/nature22363
	5YQZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon analogue	-	-	3	2018-01-17	10.1038/nature25153
	6LMK	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gs/&β;1/&γ;2	3.7	2020-04-01	10.1126/science.aaz5346
	6LML	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	-	3.9	2020-04-01	10.1126/science.aaz5346
	6WHC	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-	Gs/&β;1/&γ;2	3.4	2020-05-27	10.1074/jbc.RA120.013793
	6WPW	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/&β;1/&γ;2	3.1	2020-08-12	10.1126/science.aba3373
	7V35	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3.5	2022-03-02	10.1038/s41467-022-28683-0
	8FU6	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/&β;1/&γ;2	2.9	2023-04-12	10.1016/j.cell.2023.02.028
	8JIQ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-	Gs/&β;1/&γ;2	3.4	2023-09-13	10.1073/pnas.2303696120
	8JIT	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-	Gs/&β;1/&γ;2	2.91	2023-09-06	10.1073/pnas.2303696120
	8JIU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-	Gs/&β;1/&γ;2	2.76	2023-09-13	10.1073/pnas.2303696120
	8JRU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	Arrestin2	3.5	2023-08-16	10.1038/s41586-023-06420-x
	8JRV	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Arrestin2	3.3	2023-08-16	10.1038/s41586-023-06420-x
	8WG8	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide	chim(NtGi1-Gs)/&β;1/&γ;2	2.71	2024-03-06	10.1038/s41421-024-00649-0
	6WI9	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/&β;1/&γ;2	4.3	2020-08-12	10.1038/s41467-020-17791-4
	6WZG	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/&β;1/&γ;2	2.3	2020-08-12	10.1038/s41467-020-17791-4
	7D3S	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/&β;1/&γ;2	2.9	2020-11-04	10.1016/j.bbrc.2020.08.042

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