psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D11	A:A:E15	6.5	No	No	0	2	6
2	A:A:E16	A:A:R20	5.82	No	No	0	4	3
3	A:A:K17	A:A:R20	3.71	No	No	0	4	3
4	A:A:Q19	B:B:D83	6.53	No	Yes	0	4	8
5	A:A:Q19	B:B:N88	9.24	No	No	0	4	7
6	A:A:N23	B:B:N88	9.54	No	No	0	7	7
7	A:A:N23	B:B:K89	8.39	No	Yes	0	7	9
8	A:A:E27	A:A:Q31	8.92	No	No	0	6	4
9	A:A:E27	B:B:K89	5.4	No	Yes	0	6	9
10	A:A:K28	A:A:Q31	6.78	No	No	0	4	4
11	A:A:K32	A:A:Q29	5.42	No	No	0	4	4
12	A:A:L30	B:B:K78	4.23	No	Yes	0	5	8
13	A:A:D33	B:B:K78	4.15	No	Yes	0	5	8
14	A:A:K34	A:A:R38	6.19	No	No	0	4	4
15	A:A:R38	A:A:Y37	8.23	No	Yes	0	4	4
16	A:A:R42	A:A:Y37	16.46	Yes	Yes	0	9	4
17	A:A:Y37	B:B:L55	8.21	Yes	No	15	4	6
18	A:A:Y37	B:B:D76	3.45	Yes	Yes	15	4	9
19	A:A:H220	A:A:T40	12.32	No	No	0	7	7
20	A:A:F219	A:A:H41	9.05	Yes	No	0	8	6
21	A:A:H41	A:A:I383	7.95	No	No	0	6	8
22	A:A:F222	A:A:R42	6.41	Yes	Yes	0	7	9
23	A:A:D240	A:A:R42	7.15	Yes	Yes	0	6	9
24	A:A:F219	A:A:L43	4.87	Yes	No	16	8	7
25	A:A:I245	A:A:L43	4.28	No	No	0	7	7
26	A:A:C379	A:A:L43	3.17	No	No	16	8	7
27	A:A:L44	A:A:L46	4.15	No	No	0	9	8
28	A:A:F238	A:A:L44	12.18	Yes	No	0	9	9
29	A:A:I244	A:A:L44	7.14	No	No	0	8	9
30	A:A:L45	A:A:M221	7.07	No	No	0	8	8
31	A:A:I276	A:A:L46	4.28	No	No	0	8	8
32	A:A:G47	A:A:K53	6.97	No	No	0	9	9
33	A:A:G47	A:A:V247	3.68	No	Yes	0	9	7
34	A:A:A249	A:A:S51	3.42	No	No	0	8	9
35	A:A:D223	A:A:K53	5.53	Yes	No	0	9	9
36	A:A:I56	A:A:V247	4.61	No	Yes	17	7	7
37	A:A:I56	A:A:N292	5.66	No	Yes	17	7	9
38	A:A:D223	A:A:V57	4.38	Yes	No	0	9	7
39	A:A:M221	A:A:M60	4.33	No	No	0	8	9
40	A:A:I372	A:A:M60	5.83	No	No	0	8	9
41	A:A:G206	B:B:N119	5.09	No	No	0	8	9
42	A:A:E209	A:A:I207	4.1	No	Yes	0	9	9
43	A:A:I207	A:A:V224	3.07	Yes	No	0	9	9
44	A:A:I207	B:B:W99	3.52	Yes	Yes	0	9	9
45	A:A:D223	A:A:F208	4.78	Yes	No	0	9	5
46	A:A:E209	A:A:K211	6.75	No	No	0	9	4
47	A:A:E209	A:A:F222	10.49	No	Yes	0	9	7
48	A:A:F212	A:A:T210	3.89	No	No	0	9	7
49	A:A:H220	A:A:K211	9.17	No	No	0	7	4
50	A:A:F212	A:A:F219	10.72	No	Yes	0	9	8
51	A:A:F212	A:A:M221	3.73	No	No	0	9	8
52	A:A:N218	A:A:Q213	7.92	No	No	0	4	3
53	A:A:I372	A:A:V214	4.61	No	No	0	8	6
54	A:A:D215	A:A:R373	3.57	No	Yes	18	5	5
55	A:A:D215	A:A:F376	10.75	No	Yes	18	5	8
56	A:A:D215	R:R:V248	4.38	No	No	0	5	7
57	A:A:F219	A:A:V217	3.93	Yes	No	0	8	5
58	A:A:V217	R:R:G249	3.68	No	No	0	5	7
59	A:A:C379	A:A:F219	5.59	No	Yes	16	8	8
60	A:A:F222	A:A:H220	4.53	Yes	No	0	7	7
61	A:A:F222	A:A:F238	3.22	Yes	Yes	4	7	9
62	A:A:F222	B:B:W99	21.05	Yes	Yes	4	7	9
63	A:A:V224	A:A:W234	6.13	No	Yes	0	9	9
64	A:A:Q227	A:A:W234	4.38	No	Yes	0	9	9
65	A:A:Q227	B:B:N119	10.56	No	No	0	9	9
66	A:A:Q227	B:B:Y145	5.64	No	Yes	0	9	8
67	A:A:E230	A:A:R228	8.14	No	No	0	9	9
68	A:A:R228	B:B:T164	3.88	No	No	0	9	6
69	A:A:E230	A:A:R232	4.65	No	No	0	9	8
70	A:A:R231	A:A:W234	8	No	Yes	0	9	9
71	A:A:L272	A:A:R231	8.5	No	No	0	8	9
72	A:A:R232	B:B:D228	11.91	No	Yes	0	8	9
73	A:A:K233	B:B:Y145	3.58	Yes	Yes	3	9	8
74	A:A:K233	B:B:M188	12.96	Yes	No	0	9	8
75	A:A:K233	B:B:C204	4.85	Yes	No	3	9	7
76	A:A:K233	B:B:D228	8.3	Yes	Yes	3	9	9
77	A:A:K233	B:B:N230	5.6	Yes	No	0	9	9
78	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
79	A:A:I235	A:A:L282	4.28	No	No	0	9	9
80	A:A:Q236	A:A:W281	8.76	No	Yes	0	8	5
81	A:A:C237	B:B:Y59	8.06	No	Yes	0	8	8
82	A:A:C237	B:B:W99	5.22	No	Yes	0	8	9
83	A:A:F238	B:B:W99	13.03	Yes	Yes	4	9	9
84	A:A:F238	B:B:L117	3.65	Yes	No	4	9	9
85	A:A:D240	A:A:N239	4.04	Yes	No	4	6	8
86	A:A:N239	B:B:K57	5.6	No	Yes	4	8	9
87	A:A:N239	B:B:W332	6.78	No	Yes	4	8	9
88	A:A:D240	B:B:K57	12.44	Yes	Yes	4	6	9
89	A:A:D240	B:B:W99	6.7	Yes	Yes	4	6	9
90	A:A:A243	A:A:I288	3.25	No	No	0	8	9
91	A:A:F246	A:A:L272	7.31	No	No	0	9	8
92	A:A:F246	A:A:L289	6.09	No	Yes	0	9	9
93	A:A:N292	A:A:V247	4.43	Yes	Yes	17	9	7
94	A:A:A269	A:A:V248	5.09	No	No	0	9	7
95	A:A:L291	A:A:V248	4.47	No	No	0	8	7
96	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
97	A:A:Q294	A:A:S250	4.33	Yes	No	0	6	6
98	A:A:I341	A:A:S250	6.19	No	No	0	8	6
99	A:A:L296	A:A:S251	6.01	No	No	0	6	9
100	A:A:N264	A:A:Q267	5.28	No	No	0	9	4
101	A:A:N264	A:A:Y311	8.14	No	No	0	9	6
102	A:A:I341	A:A:L266	4.28	No	No	0	8	8
103	A:A:L270	A:A:Q267	5.32	Yes	No	0	6	4
104	A:A:K271	A:A:Q267	8.14	No	No	0	5	4
105	A:A:E344	A:A:L270	3.98	Yes	Yes	0	5	6
106	A:A:F345	A:A:L270	9.74	Yes	Yes	0	8	6
107	A:A:I348	A:A:L270	4.28	No	Yes	0	4	6
108	A:A:D274	A:A:K271	9.68	No	No	0	5	5
109	A:A:I276	A:A:L272	4.28	No	No	0	8	8
110	A:A:F273	A:A:W277	5.01	Yes	Yes	20	9	6
111	A:A:F273	A:A:V287	5.24	Yes	No	20	9	6
112	A:A:F273	A:A:F345	7.5	Yes	Yes	0	9	8
113	A:A:F273	A:A:I348	5.02	Yes	No	0	9	4
114	A:A:C359	A:A:F273	4.19	Yes	Yes	0	5	9
115	A:A:V287	A:A:W277	4.9	No	Yes	20	6	6
116	A:A:S349	A:A:W277	6.18	No	Yes	0	7	6
117	A:A:H357	A:A:W277	27.51	No	Yes	0	7	6
118	A:A:N278	A:A:S352	4.47	No	No	0	8	5
119	A:A:N279	A:A:W281	4.52	No	Yes	0	8	5
120	A:A:L282	A:A:N279	8.24	No	No	0	9	8
121	A:A:K280	A:A:W281	11.6	No	Yes	0	5	5
122	A:A:W281	B:B:D290	7.82	Yes	No	4	5	6
123	A:A:W281	B:B:R314	14.99	Yes	Yes	4	5	8
124	A:A:D284	A:A:T285	4.34	No	No	0	4	7
125	A:A:I382	A:A:S286	7.74	No	No	0	6	8
126	A:A:F290	A:A:I288	3.77	No	No	0	9	9
127	A:A:D378	A:A:I288	5.6	No	No	0	7	9
128	A:A:F345	A:A:L289	9.74	Yes	Yes	0	8	9
129	A:A:C359	A:A:L289	3.17	Yes	Yes	0	5	9
130	A:A:L289	A:A:P361	3.28	Yes	No	0	9	5
131	A:A:F290	A:A:H362	9.05	No	No	0	9	9
132	A:A:F290	A:A:T364	9.08	No	No	0	9	9
133	A:A:F363	A:A:L291	6.09	Yes	No	0	5	8
134	A:A:N292	A:A:T364	5.85	Yes	No	0	9	9
135	A:A:K293	A:A:L296	4.23	No	No	0	9	6
136	A:A:K338	A:A:Q294	5.42	Yes	Yes	7	5	6
137	A:A:F363	A:A:Q294	8.2	Yes	Yes	7	5	6
138	A:A:A337	A:A:L297	3.15	No	No	0	8	8
139	A:A:A298	A:A:V334	5.09	No	Yes	0	4	4
140	A:A:K300	A:A:K305	14.37	No	No	0	9	3
141	A:A:K300	A:A:K307	10.06	No	No	0	9	6
142	A:A:V301	A:A:V334	4.81	No	Yes	0	7	4
143	A:A:D331	A:A:L302	9.5	Yes	No	0	4	2
144	A:A:E309	A:A:S306	7.19	No	No	0	4	7
145	A:A:K307	A:A:Y311	17.91	No	No	0	6	6
146	A:A:D310	A:A:Y311	5.75	No	No	0	3	6
147	A:A:F312	A:A:F340	7.5	No	Yes	19	8	7
148	A:A:E344	A:A:F312	5.83	Yes	No	19	5	8
149	A:A:E314	A:A:R347	4.65	No	No	0	6	4
150	A:A:F315	A:A:R336	8.55	No	No	0	6	5
151	A:A:F315	A:A:F340	15	No	Yes	0	6	7
152	A:A:P321	A:A:Y318	5.56	Yes	No	0	5	6
153	A:A:F340	A:A:Y318	11.35	Yes	No	0	7	6
154	A:A:D343	A:A:Y318	8.05	No	No	0	3	6
155	A:A:P321	A:A:T320	5.25	Yes	No	0	5	1
156	A:A:T320	A:A:T335	3.14	No	No	0	1	4
157	A:A:R336	A:A:T320	5.17	No	No	0	5	1
158	A:A:D323	A:A:P321	3.22	No	Yes	0	4	5
159	A:A:P321	A:A:Y339	9.74	Yes	Yes	0	5	3
160	A:A:A324	A:A:D323	3.09	No	No	0	3	4
161	A:A:A324	A:A:Y339	4	No	Yes	0	3	3
162	A:A:E327	A:A:P326	6.29	Yes	No	7	4	1
163	A:A:P326	A:A:Y339	4.17	No	Yes	7	1	3
164	A:A:E327	A:A:T335	11.29	Yes	No	0	4	4
165	A:A:E327	A:A:K338	6.75	Yes	Yes	7	4	5
166	A:A:E327	A:A:Y339	6.73	Yes	Yes	7	4	3
167	A:A:D331	A:A:P332	6.44	Yes	No	0	4	1
168	A:A:D331	A:A:R333	15.48	Yes	No	0	4	5
169	A:A:D331	A:A:V334	8.76	Yes	Yes	0	4	4
170	A:A:F363	A:A:K338	11.17	Yes	Yes	7	5	5
171	A:A:R342	A:A:Y339	9.26	Yes	Yes	7	4	3
172	A:A:E344	A:A:F340	5.83	Yes	Yes	19	5	7
173	A:A:L346	A:A:R342	4.86	No	Yes	7	4	4
174	A:A:P361	A:A:R342	4.32	No	Yes	7	5	4
175	A:A:F363	A:A:R342	8.55	Yes	Yes	7	5	4
176	A:A:E344	A:A:R347	18.61	Yes	No	0	5	4
177	A:A:C359	A:A:L346	3.17	Yes	No	0	5	4
178	A:A:L346	A:A:P361	6.57	No	No	7	4	5
179	A:A:S349	A:A:T350	3.2	No	No	0	7	4
180	A:A:C359	A:A:S349	5.16	Yes	No	0	5	7
181	A:A:D354	A:A:S352	5.89	No	No	0	3	5
182	A:A:G355	A:A:H357	3.18	No	No	0	2	7
183	A:A:M386	A:A:R356	4.96	No	No	0	3	2
184	A:A:R356	A:A:R389	14.93	No	No	0	2	4
185	A:A:R385	A:A:Y358	7.2	Yes	No	12	5	4
186	A:A:R389	A:A:Y358	6.17	No	No	0	4	4
187	A:A:Y358	R:R:R328	5.14	No	No	12	4	6
188	A:A:D378	A:A:Y360	6.9	No	No	0	7	8
189	A:A:D381	A:A:Y360	10.34	No	No	0	8	8
190	A:A:I382	A:A:Y360	9.67	No	No	0	6	8
191	A:A:H362	A:A:R374	15.8	No	No	0	9	4
192	A:A:D378	A:A:H362	12.61	No	No	0	7	9
193	A:A:N371	A:A:T364	10.24	No	No	0	9	9
194	A:A:I372	A:A:T369	6.08	No	No	0	8	9
195	A:A:F376	A:A:R373	5.34	Yes	Yes	18	8	5
196	A:A:N377	A:A:R373	3.62	No	Yes	0	4	5
197	A:A:F376	A:A:R380	7.48	Yes	No	0	8	7
198	A:A:D381	A:A:R385	9.53	No	Yes	12	8	5
199	A:A:D381	R:R:K324	8.3	No	Yes	12	8	9
200	A:A:H387	A:A:I383	5.3	No	No	0	8	8
201	A:A:Q384	R:R:L245	3.99	No	No	0	6	8
202	A:A:Q384	R:R:K324	5.42	No	Yes	0	6	9
203	A:A:R385	R:R:K324	6.19	Yes	Yes	12	5	9
204	A:A:R385	R:R:T327	6.47	Yes	No	0	5	6
205	A:A:R385	R:R:R328	3.2	Yes	No	12	5	6
206	A:A:H387	A:A:M386	10.51	No	No	0	8	3
207	A:A:H387	R:R:L244	15.43	No	No	0	8	8
208	A:A:L388	A:A:L394	4.15	No	No	0	8	8
209	A:A:L388	R:R:L245	5.54	No	No	0	8	8
210	A:A:Q390	A:A:Y391	4.51	No	Yes	1	4	4
211	A:A:Q390	R:R:R169	9.35	No	Yes	1	4	9
212	A:A:Y391	R:R:R169	16.46	Yes	Yes	1	4	9
213	A:A:Y391	R:R:E237	5.61	Yes	Yes	1	4	9
214	A:A:Y391	R:R:Y240	6.95	Yes	Yes	1	4	8
215	A:A:Y391	R:R:L241	12.89	Yes	No	0	4	9
216	A:A:E392	R:R:K397	13.5	No	No	0	6	5
217	A:A:L393	R:R:F345	7.31	No	No	0	8	8
218	B:B:E3	B:B:L4	9.28	No	No	0	5	4
219	B:B:E3	B:B:L7	3.98	No	No	0	5	8
220	B:B:E3	G:G:I9	10.93	No	No	0	5	2
221	B:B:D5	B:B:Q9	3.92	No	No	0	1	3
222	B:B:L7	B:B:Q6	7.99	No	No	0	8	1
223	B:B:L7	G:G:A12	4.73	No	No	0	8	5
224	B:B:Q9	B:B:R8	3.5	No	No	0	3	3
225	B:B:E12	B:B:Q9	3.82	No	No	0	4	3
226	B:B:E10	B:B:L14	3.98	No	No	0	8	8
227	B:B:L14	G:G:L19	6.92	No	No	0	8	9
228	B:B:N16	B:B:R19	9.64	Yes	No	0	1	4
229	B:B:I18	B:B:R22	6.26	No	No	0	7	6
230	B:B:I18	G:G:A23	3.25	No	No	0	7	8
231	B:B:D20	B:B:K23	9.68	No	No	0	2	2
232	B:B:C25	G:G:R27	4.18	No	No	0	3	8
233	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
234	B:B:D27	G:G:K29	8.3	No	No	0	8	4
235	B:B:A28	B:B:I33	3.25	No	No	0	4	3
236	B:B:Q32	B:B:T29	8.5	No	No	0	1	3
237	B:B:L261	B:B:L30	4.15	Yes	No	0	5	5
238	B:B:L30	B:B:M262	5.65	No	No	0	5	4
239	B:B:L300	B:B:T34	4.42	No	No	0	6	5
240	B:B:I37	B:B:N36	4.25	Yes	No	0	2	1
241	B:B:I37	B:B:R283	3.76	Yes	Yes	10	2	9
242	B:B:I37	B:B:K301	4.36	Yes	Yes	10	2	5
243	B:B:D38	B:B:P39	9.66	No	No	0	1	1
244	B:B:G41	B:B:V40	3.68	No	Yes	0	1	3
245	B:B:I43	B:B:V40	3.07	No	Yes	0	3	3
246	B:B:R283	B:B:V40	6.54	Yes	Yes	10	9	3
247	B:B:D298	B:B:V40	7.3	No	Yes	10	9	3
248	B:B:V40	G:G:L51	4.47	Yes	No	10	3	6
249	B:B:I43	B:B:L284	4.28	No	No	0	3	5
250	B:B:A305	B:B:I43	3.25	No	No	0	4	3
251	B:B:L308	B:B:M45	12.72	No	No	0	7	4
252	B:B:M45	B:B:V327	4.56	No	Yes	0	4	6
253	B:B:R46	B:B:R48	8.53	No	Yes	0	5	7
254	B:B:K337	B:B:T47	4.5	Yes	No	8	6	3
255	B:B:T47	B:B:W339	4.85	No	Yes	8	3	9
256	B:B:N340	B:B:R48	4.82	No	Yes	2	9	7
257	B:B:R48	G:G:N59	3.62	Yes	Yes	2	7	9
258	B:B:R49	B:B:T87	5.17	No	No	0	7	5
259	B:B:I338	B:B:R49	3.76	Yes	No	0	5	7
260	B:B:R52	B:B:T50	7.76	No	No	0	7	3
261	B:B:K337	B:B:T50	4.5	Yes	No	0	6	3
262	B:B:L51	B:B:W82	14.81	No	Yes	2	9	9
263	B:B:L336	B:B:L51	5.54	Yes	No	2	7	9
264	B:B:F335	B:B:R52	5.34	No	No	0	4	7
265	B:B:R52	R:R:R163	8.53	No	No	0	7	8
266	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
267	B:B:H54	B:B:I58	9.28	Yes	No	0	9	9
268	B:B:H54	B:B:S72	6.97	Yes	No	2	9	9
269	B:B:H54	B:B:S74	12.55	Yes	No	0	9	9
270	B:B:H54	B:B:I80	13.26	Yes	No	2	9	8
271	B:B:H54	B:B:W82	3.17	Yes	Yes	2	9	9
272	B:B:D76	B:B:L55	10.86	Yes	No	15	9	6
273	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
274	B:B:K57	B:B:Y59	10.75	Yes	Yes	4	9	8
275	B:B:K57	B:B:Q75	6.78	Yes	No	4	9	9
276	B:B:K57	B:B:W332	5.8	Yes	Yes	4	9	9
277	B:B:I58	B:B:L336	4.28	No	Yes	0	9	7
278	B:B:Q75	B:B:Y59	22.55	No	Yes	4	9	8
279	B:B:W332	B:B:Y59	11.58	Yes	Yes	4	9	8
280	B:B:M61	B:B:W63	6.98	Yes	Yes	2	6	7
281	B:B:L70	B:B:M61	5.65	Yes	Yes	2	5	6
282	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
283	B:B:A328	B:B:M61	3.22	No	Yes	2	5	6
284	B:B:H62	B:B:R150	5.64	No	Yes	0	6	6
285	B:B:L70	B:B:W63	9.11	Yes	Yes	2	5	7
286	B:B:S84	B:B:W63	7.41	Yes	Yes	2	5	7
287	B:B:T321	B:B:W63	12.13	No	Yes	0	7	7
288	B:B:A328	B:B:W63	3.89	No	Yes	2	5	7
289	B:B:I338	B:B:W63	4.7	Yes	Yes	2	5	7
290	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
291	B:B:D66	B:B:R68	3.57	No	No	0	8	5
292	B:B:S67	B:B:T321	4.8	No	No	0	5	7
293	B:B:D83	B:B:R68	16.68	Yes	No	0	8	5
294	B:B:R68	B:B:Y85	21.61	No	No	0	5	4
295	B:B:D83	B:B:L69	4.07	Yes	No	0	8	5
296	B:B:L70	B:B:W82	7.97	Yes	Yes	2	5	9
297	B:B:L70	B:B:S84	6.01	Yes	Yes	2	5	5
298	B:B:L79	B:B:V71	4.47	No	Yes	0	7	8
299	B:B:I81	B:B:V71	3.07	No	Yes	0	7	8
300	B:B:V71	B:B:Y105	5.05	Yes	Yes	0	8	6
301	B:B:V112	B:B:V71	3.21	No	Yes	0	8	8
302	B:B:S72	B:B:W82	4.94	No	Yes	2	9	9
303	B:B:L336	B:B:S72	4.5	Yes	No	2	7	9
304	B:B:D76	B:B:S74	10.31	Yes	No	0	9	9
305	B:B:Q75	B:B:W99	7.67	No	Yes	4	9	9
306	B:B:D76	B:B:K78	8.3	Yes	Yes	0	9	8
307	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
308	B:B:A92	B:B:K78	3.21	No	Yes	0	6	8
309	B:B:I93	B:B:L79	5.71	Yes	No	0	7	7
310	B:B:C114	B:B:L79	4.76	No	No	0	8	7
311	B:B:I80	B:B:W82	12.92	No	Yes	2	8	9
312	B:B:I80	B:B:K89	4.36	No	Yes	2	8	9
313	B:B:H91	B:B:I81	3.98	No	No	0	5	7
314	B:B:I81	B:B:L126	4.28	No	No	0	7	5
315	B:B:K89	B:B:W82	12.76	Yes	Yes	2	9	9
316	B:B:L336	B:B:W82	3.42	Yes	Yes	2	7	9
317	B:B:D83	B:B:T86	5.78	Yes	No	0	8	6
318	B:B:I338	B:B:S84	3.1	Yes	Yes	2	5	5
319	B:B:S84	G:G:F61	5.28	Yes	Yes	2	5	8
320	B:B:Y85	G:G:P60	11.13	No	No	2	4	9
321	B:B:Y85	G:G:F61	10.32	No	Yes	2	4	8
322	B:B:N88	B:B:T86	7.31	No	No	0	7	6
323	B:B:H91	B:B:V90	6.92	No	No	0	5	5
324	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
325	B:B:I93	B:B:Y124	4.84	Yes	Yes	0	7	6
326	B:B:I93	B:B:V133	9.22	Yes	No	0	7	4
327	B:B:L95	B:B:V100	4.47	Yes	No	21	8	9
328	B:B:C114	B:B:L95	3.17	No	Yes	21	8	8
329	B:B:L95	B:B:Y124	7.03	Yes	Yes	0	8	6
330	B:B:E138	B:B:R96	5.82	Yes	No	0	6	6
331	B:B:D118	B:B:S97	8.83	No	No	0	9	8
332	B:B:L117	B:B:W99	3.42	No	Yes	4	9	9
333	B:B:C114	B:B:V100	5.12	No	No	21	8	9
334	B:B:G116	B:B:M101	3.49	No	No	0	9	9
335	B:B:L117	B:B:M101	4.24	No	No	0	9	9
336	B:B:M101	B:B:Y145	5.99	No	Yes	0	9	8
337	B:B:C149	B:B:T102	5.07	No	No	0	8	8
338	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
339	B:B:L126	B:B:Y105	3.52	No	Yes	0	5	6
340	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
341	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
342	B:B:D154	B:B:S108	5.89	No	No	0	6	6
343	B:B:N110	B:B:Y111	4.65	No	No	0	4	4
344	B:B:K127	B:B:N110	6.99	No	No	0	4	4
345	B:B:I123	B:B:Y111	3.63	No	No	0	6	4
346	B:B:L126	B:B:V112	4.47	No	No	0	5	8
347	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
348	B:B:G144	B:B:N119	5.09	No	No	0	8	9
349	B:B:E138	B:B:I120	4.1	Yes	No	0	6	6
350	B:B:A140	B:B:I120	3.25	No	No	0	5	6
351	B:B:C121	B:B:L139	6.35	No	Yes	0	8	9
352	B:B:C121	B:B:L146	3.17	No	No	0	8	7
353	B:B:C121	B:B:C149	3.64	No	No	0	8	8
354	B:B:S122	B:B:Y124	7.63	No	Yes	0	8	6
355	B:B:E138	B:B:S122	5.75	Yes	No	0	6	8
356	B:B:F151	B:B:I123	3.77	Yes	No	0	9	6
357	B:B:I123	B:B:I171	4.42	No	No	0	6	6
358	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
359	B:B:N125	B:B:T128	4.39	No	No	0	4	3
360	B:B:N125	B:B:S136	5.96	No	No	0	4	4
361	B:B:E138	B:B:V135	8.56	Yes	No	0	6	4
362	B:B:L139	B:B:W169	11.39	Yes	Yes	0	9	8
363	B:B:I171	B:B:L139	4.28	No	Yes	0	6	9
364	B:B:H142	B:B:L146	3.86	Yes	No	0	9	7
365	B:B:H142	B:B:S161	16.74	Yes	No	0	9	9
366	B:B:H142	B:B:W169	6.35	Yes	Yes	13	9	8
367	B:B:H142	B:B:Q176	3.71	Yes	Yes	13	9	4
368	B:B:G144	B:B:T143	3.64	No	No	0	8	5
369	B:B:D163	B:B:T143	10.12	No	No	0	9	5
370	B:B:S147	B:B:Y145	6.36	No	Yes	0	9	8
371	B:B:G162	B:B:Y145	7.24	No	Yes	3	9	8
372	B:B:D186	B:B:Y145	17.24	No	Yes	3	9	8
373	B:B:L146	B:B:T159	7.37	No	No	0	7	9
374	B:B:C148	B:B:R150	5.57	No	Yes	0	6	6
375	B:B:C149	B:B:T159	3.38	No	No	0	8	9
376	B:B:L152	B:B:Q156	3.99	No	No	0	3	5
377	B:B:L152	B:B:T196	5.9	No	No	0	3	1
378	B:B:L152	B:B:V213	4.47	No	No	0	3	4
379	B:B:D153	B:B:D154	9.31	No	No	0	5	6
380	B:B:D170	B:B:N155	4.04	No	No	0	9	3
381	B:B:E172	B:B:N155	7.89	No	No	0	6	3
382	B:B:L168	B:B:Q156	7.99	No	No	0	6	5
383	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
384	B:B:F199	B:B:V158	3.93	Yes	No	0	9	5
385	B:B:T159	B:B:W169	3.64	No	Yes	0	9	8
386	B:B:C166	B:B:S160	3.44	Yes	No	6	8	6
387	B:B:S160	B:B:V187	6.46	No	No	6	6	9
388	B:B:L190	B:B:S160	4.5	No	No	0	5	6
389	B:B:D163	B:B:S161	7.36	No	No	0	9	9
390	B:B:D186	B:B:G162	6.71	No	No	3	9	9
391	B:B:D163	B:B:T165	4.34	No	No	0	9	7
392	B:B:T165	B:B:T181	4.71	No	No	0	7	2
393	B:B:C166	B:B:F180	4.19	Yes	Yes	6	8	7
394	B:B:C166	B:B:V187	5.12	Yes	No	6	8	9
395	B:B:C166	B:B:S201	3.44	Yes	No	0	8	9
396	B:B:A167	B:B:W169	3.89	No	Yes	13	4	8
397	B:B:A167	B:B:Q176	6.06	No	Yes	13	4	4
398	B:B:L168	B:B:T178	5.9	No	No	0	6	4
399	B:B:Q176	B:B:W169	16.43	Yes	Yes	13	4	8
400	B:B:D170	B:B:T173	5.78	No	No	0	9	5
401	B:B:Q175	B:B:T173	15.59	No	No	0	4	5
402	B:B:Q176	B:B:T179	4.25	Yes	No	0	4	4
403	B:B:T177	B:B:T178	3.14	No	No	0	4	4
404	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
405	B:B:F180	B:B:F199	7.5	Yes	Yes	6	7	9
406	B:B:F180	B:B:W211	13.03	Yes	Yes	6	7	8
407	B:B:H183	B:B:V187	5.54	Yes	No	6	9	9
408	B:B:H183	B:B:S201	6.97	Yes	No	0	9	9
409	B:B:A203	B:B:H183	8.78	No	Yes	6	8	9
410	B:B:D205	B:B:H183	5.04	Yes	Yes	6	9	9
411	B:B:H183	B:B:K209	11.79	Yes	Yes	6	9	6
412	B:B:D205	B:B:T184	10.12	Yes	No	0	9	3
413	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
414	B:B:F199	B:B:L190	6.09	Yes	No	0	9	5
415	B:B:F199	B:B:L192	4.87	Yes	No	0	9	5
416	B:B:G238	B:B:P194	4.06	No	No	0	7	4
417	B:B:D195	B:B:R197	14.29	No	No	0	5	5
418	B:B:L198	B:B:L210	6.92	No	No	0	3	5
419	B:B:F199	B:B:W211	12.03	Yes	Yes	6	9	8
420	B:B:I232	B:B:V200	6.14	Yes	Yes	3	8	6
421	B:B:F234	B:B:V200	11.8	No	Yes	3	5	6
422	B:B:F241	B:B:V200	3.93	Yes	Yes	3	6	6
423	B:B:S201	B:B:W211	9.88	No	Yes	0	9	8
424	B:B:A203	B:B:D205	3.09	No	Yes	6	8	9
425	B:B:C204	B:B:D228	10.89	No	Yes	3	7	9
426	B:B:D205	B:B:S207	7.36	Yes	No	0	9	5
427	B:B:S207	B:B:T221	3.2	No	No	0	5	7
428	B:B:K209	B:B:W211	6.96	Yes	Yes	6	6	8
429	B:B:C218	B:B:K209	4.85	No	Yes	6	5	6
430	B:B:K209	B:B:T221	10.51	Yes	No	0	6	7
431	B:B:C218	B:B:W211	3.92	No	Yes	6	5	8
432	B:B:D212	B:B:E215	6.5	No	No	0	9	3
433	B:B:D212	B:B:R219	8.34	No	No	0	9	5
434	B:B:F222	B:B:Q220	9.37	Yes	No	3	8	7
435	B:B:D258	B:B:Q220	9.14	No	No	3	7	7
436	B:B:Q220	G:G:I25	4.12	No	No	0	7	2
437	B:B:T221	G:G:E22	5.64	No	No	0	7	9
438	B:B:F222	B:B:F241	8.57	Yes	Yes	3	8	6
439	B:B:F222	B:B:F253	8.57	Yes	Yes	3	8	6
440	B:B:D258	B:B:F222	4.78	No	Yes	3	7	8
441	B:B:E260	B:B:G224	3.27	No	No	0	6	6
442	B:B:H225	B:B:I229	10.61	Yes	No	0	9	7
443	B:B:H225	B:B:T243	12.32	Yes	No	3	9	8
444	B:B:H225	B:B:S245	11.16	Yes	No	3	9	9
445	B:B:D247	B:B:H225	3.78	Yes	Yes	3	9	9
446	B:B:H225	B:B:R251	7.9	Yes	Yes	0	9	8
447	B:B:F253	B:B:H225	3.39	Yes	Yes	3	6	9
448	B:B:D247	B:B:E226	15.59	Yes	No	0	9	3
449	B:B:D228	B:B:S227	5.89	Yes	No	3	9	6
450	B:B:D246	B:B:S227	5.89	No	No	3	9	6
451	B:B:D247	B:B:S227	5.89	Yes	No	3	9	6
452	B:B:D228	B:B:D246	3.99	Yes	No	3	9	9
453	B:B:D246	B:B:N230	10.77	No	No	0	9	9
454	B:B:A231	B:B:V276	3.39	No	No	0	5	6
455	B:B:F241	B:B:I232	3.77	Yes	Yes	3	6	8
456	B:B:F234	B:B:F241	9.65	No	Yes	3	5	6
457	B:B:F235	B:B:P236	10.11	Yes	Yes	5	6	7
458	B:B:F235	B:B:F278	8.57	Yes	Yes	5	6	7
459	B:B:F235	B:B:G282	4.52	Yes	No	5	6	9
460	B:B:F235	G:G:L37	4.87	Yes	No	0	6	7
461	B:B:F235	G:G:Y40	7.22	Yes	Yes	5	6	6
462	B:B:F278	B:B:P236	7.22	Yes	Yes	5	7	7
463	B:B:G282	B:B:P236	4.06	No	Yes	5	9	7
464	B:B:P236	G:G:Y40	4.17	Yes	Yes	5	7	6
465	B:B:N237	B:B:N239	4.09	Yes	No	0	5	2
466	B:B:N237	G:G:D36	4.04	Yes	No	0	5	5
467	B:B:N237	G:G:Y40	10.47	Yes	Yes	0	5	6
468	B:B:N239	B:B:R256	7.23	No	Yes	0	2	9
469	B:B:F241	B:B:F253	10.72	Yes	Yes	3	6	6
470	B:B:F253	B:B:T243	7.78	Yes	No	3	6	8
471	B:B:G244	B:B:I273	5.29	No	No	0	5	6
472	B:B:D247	B:B:S245	8.83	Yes	No	3	9	9
473	B:B:D247	B:B:T249	7.23	Yes	No	0	9	6
474	B:B:A248	B:B:I269	3.25	No	No	0	5	4
475	B:B:R251	B:B:T249	5.17	Yes	No	0	8	6
476	B:B:S265	B:B:T249	3.2	No	No	0	2	6
477	B:B:C250	B:B:Y264	5.38	No	Yes	5	8	5
478	B:B:C250	B:B:I273	3.27	No	No	0	8	6
479	B:B:C250	B:B:L285	3.17	No	Yes	5	8	6
480	B:B:E260	B:B:R251	16.28	No	Yes	0	6	8
481	B:B:R251	B:B:T263	9.06	Yes	No	0	8	1
482	B:B:L252	B:B:L261	6.92	No	Yes	0	7	5
483	B:B:L252	B:B:Y264	7.03	No	Yes	0	7	5
484	B:B:E260	B:B:F253	11.66	No	Yes	0	6	6
485	B:B:D254	B:B:R256	3.57	Yes	Yes	0	9	9
486	B:B:A257	B:B:D254	3.09	No	Yes	0	7	9
487	B:B:D254	B:B:L261	4.07	Yes	Yes	0	9	5
488	B:B:D254	G:G:A33	3.09	Yes	No	0	9	7
489	B:B:R256	G:G:I28	6.26	Yes	No	0	9	4
490	B:B:R256	G:G:D36	4.76	Yes	No	0	9	5
491	B:B:D258	G:G:R27	9.53	No	No	0	7	8
492	B:B:M262	B:B:Y264	8.38	No	Yes	0	4	5
493	B:B:S265	B:B:T263	3.2	No	No	0	2	1
494	B:B:L285	B:B:Y264	8.21	Yes	Yes	5	6	5
495	B:B:W297	B:B:Y264	4.82	Yes	Yes	5	8	5
496	B:B:D267	B:B:H266	6.3	No	Yes	0	3	4
497	B:B:H266	B:B:I269	5.3	Yes	No	0	4	4
498	B:B:H266	B:B:W297	4.23	Yes	Yes	5	4	8
499	B:B:H266	B:B:R304	13.54	Yes	No	5	4	5
500	B:B:D267	B:B:N268	12.12	No	No	0	3	4
501	B:B:I269	B:B:Y289	4.84	No	Yes	0	4	7
502	B:B:C271	B:B:D290	3.11	No	No	0	5	6
503	B:B:C271	B:B:D291	6.22	No	No	0	5	8
504	B:B:I273	B:B:Y289	8.46	No	Yes	0	6	7
505	B:B:S275	B:B:T274	4.8	No	No	0	8	8
506	B:B:R314	B:B:T274	3.88	Yes	No	0	8	8
507	B:B:S277	B:B:V320	3.23	No	No	0	5	7
508	B:B:F278	B:B:L285	4.87	Yes	Yes	5	7	6
509	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
510	B:B:S281	G:G:D48	5.89	No	Yes	0	9	9
511	B:B:D298	B:B:R283	13.1	No	Yes	10	9	9
512	B:B:L300	B:B:R283	4.86	No	Yes	0	6	9
513	B:B:K301	B:B:R283	3.71	Yes	Yes	10	5	9
514	B:B:R283	G:G:L51	3.64	Yes	No	10	9	6
515	B:B:L284	B:B:V296	5.96	No	No	0	5	5
516	B:B:L285	B:B:W297	4.56	Yes	Yes	5	6	8
517	B:B:A299	B:B:L285	3.15	No	Yes	0	5	6
518	B:B:C294	B:B:L286	3.17	Yes	No	22	5	7
519	B:B:L286	B:B:L318	4.15	No	No	22	7	6
520	B:B:L286	B:B:V327	4.47	No	Yes	0	7	6
521	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
522	B:B:C294	B:B:G288	3.92	Yes	No	0	5	7
523	B:B:D291	B:B:Y289	4.6	No	Yes	0	8	7
524	B:B:N295	B:B:Y289	9.3	Yes	Yes	5	6	7
525	B:B:W297	B:B:Y289	5.79	Yes	Yes	5	8	7
526	B:B:D290	B:B:R314	9.53	No	Yes	4	6	8
527	B:B:D291	B:B:N293	13.46	No	No	0	8	5
528	B:B:A309	B:B:N293	3.13	No	No	0	3	5
529	B:B:C294	B:B:L308	6.35	Yes	No	0	5	7
530	B:B:C294	B:B:L318	3.17	Yes	No	22	5	6
531	B:B:N295	B:B:W297	3.39	Yes	Yes	5	6	8
532	B:B:N295	B:B:R304	7.23	Yes	No	5	6	5
533	B:B:G306	B:B:V296	3.68	No	No	0	4	5
534	B:B:R304	B:B:W297	9	No	Yes	5	5	8
535	B:B:D298	B:B:K301	9.68	No	Yes	10	9	5
536	B:B:V307	R:R:L412	4.47	No	No	0	3	4
537	B:B:L308	B:B:W339	9.11	No	Yes	0	7	9
538	B:B:A309	R:R:H409	4.39	No	No	0	3	7
539	B:B:G310	R:R:H409	4.77	No	No	0	5	7
540	B:B:H311	B:B:V315	4.15	Yes	No	0	9	7
541	B:B:H311	B:B:T329	6.85	Yes	No	0	9	8
542	B:B:H311	B:B:S331	16.74	Yes	No	8	9	9
543	B:B:D333	B:B:H311	5.04	Yes	Yes	8	9	9
544	B:B:H311	B:B:K337	10.48	Yes	Yes	8	9	6
545	B:B:D312	B:B:N313	6.73	No	No	8	5	7
546	B:B:D312	B:B:D333	3.99	No	Yes	8	5	9
547	B:B:D312	R:R:R405	14.29	No	Yes	0	5	8
548	B:B:D333	B:B:N313	5.39	Yes	No	8	9	7
549	B:B:R314	B:B:W332	33.99	Yes	Yes	4	8	9
550	B:B:C317	B:B:S316	3.44	No	No	0	7	9
551	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
552	B:B:V320	B:B:V327	3.21	No	Yes	0	7	6
553	B:B:G324	B:B:T321	3.64	No	No	0	9	7
554	B:B:D323	B:B:M325	6.93	No	No	0	7	5
555	B:B:M325	G:G:P49	10.06	No	No	0	5	7
556	B:B:A326	G:G:F61	8.32	No	Yes	0	7	8
557	B:B:V327	G:G:L50	4.47	Yes	No	0	6	9
558	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
559	B:B:G330	B:B:L336	3.42	No	Yes	0	5	7
560	B:B:D333	B:B:S331	8.83	Yes	No	8	9	9
561	B:B:D333	B:B:F335	10.75	Yes	No	0	9	4
562	B:B:K337	B:B:W339	5.8	Yes	Yes	8	6	9
563	B:B:I338	G:G:F61	6.28	Yes	Yes	2	5	8
564	B:B:N340	G:G:N59	10.9	No	Yes	2	9	9
565	B:B:N340	G:G:F61	4.83	No	Yes	2	9	8
566	G:G:S8	G:G:T6	4.8	No	No	0	4	3
567	G:G:I9	G:G:R13	13.78	No	No	0	2	6
568	G:G:E17	G:G:M21	5.41	No	No	0	6	1
569	G:G:K20	G:G:N24	6.99	No	No	0	6	1
570	G:G:I25	G:G:R27	8.77	No	No	0	2	8
571	G:G:I28	G:G:K32	8.72	No	No	0	4	5
572	G:G:H44	G:G:Y40	14.16	No	Yes	0	6	6
573	G:G:E47	G:G:K46	4.05	No	No	0	3	1
574	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
575	G:G:D48	G:G:L51	12.21	Yes	No	0	9	6
576	G:G:P55	G:G:V54	3.53	No	No	2	5	6
577	G:G:E58	G:G:V54	4.28	No	No	2	5	6
578	G:G:N59	G:G:V54	4.43	Yes	No	2	9	6
579	G:G:E58	G:G:P55	11	No	No	2	5	5
580	G:G:E58	G:G:S57	4.31	No	No	0	5	6
581	G:G:N59	G:G:P60	6.52	Yes	No	2	9	9
582	G:G:F61	G:G:P60	5.78	Yes	No	2	8	9
583	R:R:A126	R:R:N124	4.69	No	No	0	1	1
584	R:R:F127	R:R:N124	12.08	No	No	0	2	1
585	R:R:F127	R:R:R131	9.62	No	No	0	2	3
586	R:R:L128	R:R:L132	6.92	No	No	0	3	3
587	R:R:Q130	R:R:R131	5.84	No	No	0	3	3
588	R:R:Q130	R:R:R370	7.01	No	Yes	0	3	5
589	R:R:E135	R:R:L132	3.98	No	No	0	3	3
590	R:R:F371	R:R:I133	3.77	No	No	0	4	4
591	R:R:L134	R:R:L137	6.92	No	No	14	5	6
592	R:R:L134	R:R:L374	4.15	No	Yes	14	5	6
593	R:R:L137	R:R:L374	6.92	No	Yes	14	6	6
594	R:R:Q138	R:R:Y141	4.51	No	Yes	0	5	7
595	R:R:Y141	R:R:Y145	19.86	Yes	Yes	9	7	7
596	R:R:I187	R:R:Y141	3.63	No	Yes	9	7	7
597	R:R:I378	R:R:Y141	14.51	No	Yes	0	8	7
598	R:R:S146	R:R:V143	3.23	No	Yes	0	7	5
599	R:R:G144	R:R:S382	3.71	No	No	0	8	9
600	R:R:I187	R:R:Y145	9.67	No	Yes	9	7	7
601	R:R:L188	R:R:Y145	5.86	No	Yes	0	7	7
602	R:R:S381	R:R:Y145	5.09	No	Yes	0	5	7
603	R:R:F386	R:R:L147	10.96	Yes	No	0	5	5
604	R:R:A184	R:R:L149	3.15	No	No	0	8	6
605	R:R:F386	R:R:T151	3.89	Yes	No	11	5	7
606	R:R:S389	R:R:T151	3.2	No	No	0	8	7
607	R:R:T151	R:R:V390	6.35	No	Yes	11	7	5
608	R:R:F177	R:R:L152	4.87	No	Yes	0	9	9
609	R:R:F180	R:R:L152	3.65	Yes	Yes	0	8	9
610	R:R:L152	R:R:M181	7.07	Yes	No	0	9	7
611	R:R:L152	R:R:S389	9.01	Yes	No	0	9	8
612	R:R:L156	R:R:M181	4.24	No	No	0	6	7
613	R:R:F162	R:R:I158	8.79	Yes	No	0	7	8
614	R:R:I174	R:R:L159	7.14	No	No	0	7	8
615	R:R:F162	R:R:L161	12.18	Yes	No	0	7	3
616	R:R:E402	R:R:F162	17.49	No	Yes	0	8	7
617	R:R:F162	R:R:I403	6.28	Yes	No	0	7	5
618	R:R:H166	R:R:R163	6.77	No	No	0	7	8
619	R:R:E402	R:R:R164	13.96	No	No	0	8	7
620	R:R:L165	R:R:N170	5.49	No	No	0	9	9
621	R:R:E398	R:R:L165	6.63	No	No	0	9	9
622	R:R:H166	R:R:Y171	10.89	No	No	0	7	6
623	R:R:C167	R:R:N170	4.72	No	No	0	8	9
624	R:R:T168	R:R:Y240	3.75	No	Yes	1	8	8
625	R:R:E253	R:R:T168	7.06	No	No	1	5	8
626	R:R:F256	R:R:T168	3.89	No	No	0	5	8
627	R:R:H173	R:R:R169	19.18	No	Yes	1	9	9
628	R:R:R169	R:R:Y240	4.12	Yes	Yes	1	9	8
629	R:R:N396	R:R:R169	10.85	No	Yes	1	9	9
630	R:R:E398	R:R:R169	3.49	No	Yes	1	9	9
631	R:R:F256	R:R:Y171	8.25	No	No	0	5	6
632	R:R:I172	R:R:W233	4.7	No	Yes	1	9	9
633	R:R:I172	R:R:V236	3.07	No	No	1	9	8
634	R:R:I172	R:R:Y240	4.84	No	Yes	1	9	8
635	R:R:E237	R:R:H173	3.69	Yes	No	1	9	9
636	R:R:H173	R:R:Y392	25.04	No	No	1	9	8
637	R:R:N175	R:R:W233	13.56	No	Yes	1	9	9
638	R:R:L260	R:R:N175	4.12	No	No	1	6	9
639	R:R:N175	R:R:W264	3.39	No	Yes	1	9	9
640	R:R:F180	R:R:L176	4.87	Yes	No	0	8	9
641	R:R:C393	R:R:F177	4.19	No	No	0	9	9
642	R:R:A229	R:R:S179	3.42	No	No	1	8	9
643	R:R:N230	R:R:S179	7.45	No	No	1	9	9
644	R:R:S179	R:R:W264	4.94	No	Yes	1	9	9
645	R:R:F180	R:R:R183	5.34	Yes	Yes	1	8	8
646	R:R:F180	R:R:N230	25.37	Yes	No	1	8	9
647	R:R:F180	R:R:Q384	4.68	Yes	No	1	8	9
648	R:R:F180	R:R:V388	3.93	Yes	No	0	8	9
649	R:R:C226	R:R:L182	4.76	No	No	0	6	7
650	R:R:C226	R:R:R183	4.18	No	Yes	0	6	8
651	R:R:N230	R:R:R183	8.44	No	Yes	1	9	8
652	R:R:Q384	R:R:R183	7.01	No	Yes	1	9	8
653	R:R:A186	R:R:V222	3.39	No	No	0	6	5
654	R:R:I187	R:R:R190	6.26	No	Yes	9	7	6
655	R:R:D191	R:R:R190	5.96	No	Yes	0	7	6
656	R:R:L194	R:R:R190	8.5	Yes	Yes	9	7	6
657	R:R:Q220	R:R:R190	8.18	No	Yes	9	5	6
658	R:R:R190	R:R:W287	7	Yes	Yes	9	6	9
659	R:R:A215	R:R:L193	3.15	No	No	0	3	5
660	R:R:L194	R:R:P195	3.28	Yes	No	0	7	3
661	R:R:C216	R:R:L194	3.17	No	Yes	0	9	7
662	R:R:L194	R:R:W287	6.83	Yes	Yes	9	7	9
663	R:R:C216	R:R:C286	7.28	No	No	0	9	9
664	R:R:R217	R:R:R278	10.66	No	No	0	8	8
665	R:R:Q220	R:R:W287	20.81	No	Yes	9	5	9
666	R:R:I221	R:R:W274	3.52	No	Yes	24	5	8
667	R:R:I221	R:R:V275	7.68	No	No	24	5	6
668	R:R:Q224	R:R:W274	7.67	No	Yes	0	6	8
669	R:R:I299	R:R:Q224	5.49	No	No	0	7	6
670	R:R:W264	R:R:Y225	7.72	Yes	No	0	9	8
671	R:R:A268	R:R:Y225	4	No	No	0	3	8
672	R:R:G228	R:R:P267	4.06	No	Yes	0	5	9
673	R:R:A229	R:R:W264	3.89	No	Yes	1	8	9
674	R:R:A229	R:R:P267	3.74	No	Yes	0	8	9
675	R:R:I303	R:R:Y231	3.63	No	Yes	0	7	8
676	R:R:V352	R:R:Y231	7.57	Yes	Yes	25	6	8
677	R:R:V355	R:R:Y231	11.36	No	Yes	25	5	8
678	R:R:G263	R:R:T232	3.64	No	No	0	9	6
679	R:R:P267	R:R:T232	12.24	Yes	No	0	9	6
680	R:R:V236	R:R:W233	7.36	No	Yes	1	8	9
681	R:R:G263	R:R:W233	7.04	No	Yes	0	9	9
682	R:R:W233	R:R:W264	17.81	Yes	Yes	1	9	9
683	R:R:L234	R:R:P348	4.93	No	No	0	9	9
684	R:R:L235	R:R:N310	8.24	Yes	No	0	8	9
685	R:R:V236	R:R:Y259	3.79	No	Yes	0	8	8
686	R:R:E237	R:R:G238	4.91	Yes	No	0	9	9
687	R:R:E237	R:R:Y392	11.22	Yes	No	1	9	8
688	R:R:L244	R:R:Y240	4.69	No	Yes	0	8	8
689	R:R:E253	R:R:Y240	3.37	No	Yes	1	5	8
690	R:R:Y240	R:R:Y259	7.94	Yes	Yes	0	8	8
691	R:R:I317	R:R:L241	5.71	No	No	0	9	9
692	R:R:H242	R:R:V246	8.3	Yes	No	0	8	7
693	R:R:H242	R:R:R316	6.77	Yes	No	0	8	8
694	R:R:I320	R:R:L245	5.71	No	No	0	8	8
695	R:R:E252	R:R:L247	5.3	No	No	0	7	5
696	R:R:H255	R:R:Y258	4.36	No	No	0	4	3
697	R:R:H255	R:R:Y259	3.27	No	Yes	0	4	8
698	R:R:R257	R:R:Y258	5.14	No	No	0	3	3
699	R:R:L260	R:R:W264	3.42	No	Yes	1	6	9
700	R:R:G263	R:R:L262	3.42	No	No	0	9	6
701	R:R:A266	R:R:P267	3.74	No	Yes	0	4	9
702	R:R:F270	R:R:L269	6.09	No	No	0	5	4
703	R:R:F270	R:R:P302	14.45	No	No	0	5	9
704	R:R:I272	R:R:P273	3.39	No	No	0	2	4
705	R:R:V275	R:R:W274	4.9	No	Yes	24	6	8
706	R:R:R278	R:R:W274	5	No	Yes	0	8	8
707	R:R:I298	R:R:W274	5.87	No	Yes	0	8	8
708	R:R:R278	R:R:T284	7.76	No	No	0	8	4
709	R:R:L280	R:R:Y279	4.69	No	No	0	3	3
710	R:R:L280	R:R:Y281	5.86	No	No	0	3	3
711	R:R:E282	R:R:E291	16.49	No	No	0	5	4
712	R:R:E282	R:R:I295	9.56	No	No	0	5	3
713	R:R:C286	R:R:W287	3.92	No	Yes	0	9	9
714	R:R:I295	R:R:N290	7.08	No	No	0	3	6
715	R:R:A294	R:R:V292	3.39	No	No	0	3	6
716	R:R:K293	R:R:W297	10.44	No	No	0	5	7
717	R:R:W296	R:R:W297	9.37	No	No	0	6	7
718	R:R:R300	R:R:W296	24.99	No	No	0	7	6
719	R:R:L304	R:R:R300	23.08	No	No	0	4	7
720	R:R:R300	R:R:V356	9.15	No	No	0	7	6
721	R:R:P302	R:R:T301	3.5	No	No	0	9	4
722	R:R:I307	R:R:L349	4.28	No	No	0	7	9
723	R:R:I307	R:R:V352	16.9	No	Yes	0	7	6
724	R:R:L308	R:R:L312	4.15	No	No	0	3	4
725	R:R:F311	R:R:I315	12.56	No	No	0	6	5
726	R:R:F314	R:R:F345	5.36	No	No	0	9	8
727	R:R:F314	R:R:L346	8.53	No	No	0	9	9
728	R:R:L318	R:R:S342	4.5	No	No	0	7	9
729	R:R:L321	R:R:L325	5.54	No	Yes	0	9	7
730	R:R:L322	R:R:R338	6.07	No	No	0	5	9
731	R:R:K324	R:R:S323	3.06	Yes	No	0	9	7
732	R:R:D334	R:R:L325	8.14	Yes	Yes	0	6	7
733	R:R:M330	R:R:R328	7.44	No	No	0	5	6
734	R:R:D334	R:R:M330	6.93	Yes	No	0	6	5
735	R:R:R331	R:R:R333	6.4	No	No	0	5	6
736	R:R:C332	R:R:R336	4.18	No	No	0	6	6
737	R:R:R336	R:R:Y335	4.12	No	No	0	6	5
738	R:R:L337	R:R:R341	6.07	No	No	0	7	9
739	R:R:L339	R:R:S342	4.5	No	No	27	9	9
740	R:R:L339	R:R:T343	4.42	No	No	27	9	9
741	R:R:A340	R:R:R341	4.15	No	No	0	8	9
742	R:R:S342	R:R:T343	3.2	No	No	27	9	9
743	R:R:P348	R:R:V347	3.53	No	No	0	9	8
744	R:R:L387	R:R:V347	10.43	No	No	0	6	8
745	R:R:L350	R:R:L380	9.69	No	No	0	9	7
746	R:R:V352	R:R:V355	3.21	Yes	No	25	6	5
747	R:R:E354	R:R:E377	19.03	No	No	0	7	7
748	R:R:E354	R:R:L380	3.98	No	No	0	7	7
749	R:R:E354	R:R:S381	8.62	No	No	0	7	5
750	R:R:F357	R:R:K373	7.44	No	No	0	7	7
751	R:R:E377	R:R:F357	7	No	No	0	7	7
752	R:R:E363	R:R:L374	3.98	No	Yes	0	5	6
753	R:R:G367	R:R:R370	4.5	No	Yes	0	4	5
754	R:R:A368	R:R:F371	4.16	No	No	0	1	4
755	R:R:F371	R:R:R370	4.28	No	Yes	0	4	5
756	R:R:F379	R:R:F383	11.79	No	No	0	6	6
757	R:R:F383	R:R:F386	7.5	No	Yes	0	6	5
758	R:R:F383	R:R:L387	9.74	No	No	0	6	6
759	R:R:G385	R:R:Q384	6.58	No	No	0	9	9
760	R:R:F386	R:R:V390	9.18	Yes	Yes	11	5	5
761	R:R:L391	R:R:V390	4.47	Yes	Yes	11	7	5
762	R:R:F394	R:R:V390	5.24	Yes	Yes	11	8	5
763	R:R:F394	R:R:L391	4.87	Yes	Yes	11	8	7
764	R:R:I395	R:R:L391	5.71	No	Yes	11	5	7
765	R:R:F394	R:R:I395	10.05	Yes	No	11	8	5
766	R:R:E398	R:R:N396	13.15	No	No	1	9	9
767	R:R:N396	R:R:V399	7.39	No	No	0	9	9
768	R:R:K397	R:R:Q400	5.42	No	No	0	5	8
769	R:R:R405	R:R:S401	3.95	Yes	No	0	8	4
770	R:R:I403	R:R:R404	6.26	No	No	0	5	6
771	R:R:H409	R:R:R405	11.28	No	Yes	0	7	8
772	R:R:H408	R:R:W407	7.41	No	No	0	4	5
773	R:R:C410	R:R:R414	4.18	No	No	0	4	5
774	A:A:C365	A:A:Q294	3.05	No	Yes	0	8	6
775	B:B:C25	B:B:Q259	3.05	No	No	0	3	6
776	A:A:M60	A:A:V375	3.04	No	No	0	9	9
777	A:A:I244	A:A:T285	3.04	No	No	0	8	7
778	A:A:K338	A:A:V334	3.04	Yes	Yes	0	5	4
779	R:R:K293	R:R:V292	3.04	No	No	0	5	6
780	G:G:A43	G:G:E42	3.02	No	No	0	4	1
781	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
782	A:A:G355	A:A:R283	3	No	No	0	2	3
783	B:B:S279	G:G:L50	3	No	No	0	9	9
784	R:R:L152	R:R:S148	3	Yes	No	0	9	9
785	R:R:L247	R:R:S243	3	No	No	0	5	7
786	R:R:L182	R:R:V222	2.98	No	No	0	7	5
787	R:R:L235	R:R:V239	2.98	Yes	No	0	8	7
788	B:B:N295	B:B:V307	2.96	Yes	No	0	6	3
789	R:R:L235	R:R:T306	2.95	Yes	No	0	8	7
790	A:A:S205	B:B:D118	2.94	No	No	0	7	9
791	A:A:D274	A:A:S275	2.94	No	No	0	5	8
792	A:A:D310	A:A:S306	2.94	No	No	0	3	7
793	B:B:D27	G:G:S31	2.94	No	No	0	8	9
794	R:R:I309	R:R:I313	2.94	No	No	0	6	8
795	R:R:I313	R:R:I317	2.94	No	No	26	8	9
796	A:A:N218	A:A:T40	2.92	No	No	0	4	7
797	A:A:N54	A:A:T55	2.92	No	No	0	9	9
798	B:B:D83	B:B:V90	2.92	Yes	No	0	8	5
799	A:A:I26	B:B:K89	2.91	No	Yes	0	9	9
800	R:R:G351	R:R:Y231	2.9	No	Yes	0	9	8
801	B:B:M217	G:G:M21	2.89	No	No	0	3	1
802	R:R:I133	R:R:L134	2.85	No	No	0	4	5
803	R:R:I158	R:R:L154	2.85	No	No	0	8	5
804	R:R:I158	R:R:L159	2.85	No	No	0	8	8
805	R:R:I309	R:R:L235	2.85	No	Yes	0	6	8
806	R:R:I276	R:R:L280	2.85	No	No	0	3	3
807	A:A:Q12	A:A:T9	2.83	No	No	0	2	6
808	R:R:L153	R:R:M181	2.83	No	No	0	3	7
809	R:R:I307	R:R:N310	2.83	No	No	0	7	9
810	A:A:E16	B:B:T86	2.82	No	No	0	4	6
811	A:A:E327	A:A:T325	2.82	Yes	No	0	4	2
812	A:A:I207	B:B:D118	2.8	Yes	No	0	9	9
813	A:A:K293	A:A:N292	2.8	No	Yes	0	9	9
814	B:B:F235	G:G:C41	2.79	Yes	No	0	6	7
815	A:A:L388	A:A:L393	2.77	No	No	0	8	8
816	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
817	B:B:L210	B:B:L255	2.77	No	No	0	5	6
818	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
819	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
820	G:G:L15	G:G:L19	2.77	No	No	0	2	9
821	R:R:A155	R:R:F177	2.77	No	No	0	9	9
822	R:R:A219	R:R:R190	2.77	No	Yes	0	6	6
823	R:R:L346	R:R:L349	2.77	No	No	0	9	9
824	R:R:L159	R:R:N170	2.75	No	No	0	8	9
825	A:A:H41	A:A:T242	2.74	No	No	0	6	8
826	B:B:I18	B:B:Q17	2.74	No	No	0	7	4
827	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
828	G:G:E22	G:G:L19	2.65	No	No	0	9	9
829	R:R:H242	R:R:I313	2.65	Yes	No	26	8	8
830	R:R:H242	R:R:I317	2.65	Yes	No	26	8	9
831	B:B:N16	B:B:Q13	2.64	Yes	No	0	1	1
832	B:B:F335	B:B:S334	2.64	No	No	0	4	4
833	B:B:E130	B:B:N132	2.63	No	No	0	3	3
834	R:R:E125	R:R:N124	2.63	No	No	0	3	1
835	A:A:R42	A:A:V241	2.62	Yes	No	0	9	9
836	A:A:R373	A:A:V214	2.62	Yes	No	0	5	6
837	A:A:F376	A:A:V217	2.62	Yes	No	0	8	5
838	A:A:F238	A:A:V241	2.62	Yes	No	0	9	9
839	R:R:R183	R:R:V227	2.62	Yes	No	0	8	6
840	R:R:Q220	R:R:Q224	2.56	No	No	0	5	6
841	A:A:E327	A:A:E330	2.54	Yes	No	0	4	3
842	R:R:S243	R:R:Y259	2.54	No	Yes	0	7	8
843	A:A:F315	A:A:I308	2.51	No	No	0	6	7
844	B:B:I171	B:B:R137	2.51	No	No	0	6	5
845	A:A:S352	A:A:W277	2.47	No	Yes	0	5	6
846	B:B:S98	B:B:W99	2.47	No	Yes	0	8	9
847	R:R:V271	R:R:W274	2.45	No	Yes	0	6	8
848	B:B:F241	B:B:L255	2.44	Yes	No	0	6	6
849	R:R:F127	R:R:L128	2.44	No	No	0	2	3
850	R:R:F311	R:R:L349	2.44	No	No	0	6	9
851	R:R:F376	R:R:L380	2.44	No	No	0	4	7
852	B:B:L190	B:B:R150	2.43	No	Yes	0	5	6
853	B:B:L192	B:B:R150	2.43	No	Yes	0	5	6
854	B:B:L210	B:B:R219	2.43	No	No	0	5	5
855	R:R:T178	R:R:W264	2.43	No	Yes	0	3	9
856	R:R:N283	R:R:R217	2.41	No	No	0	6	8
857	B:B:D20	B:B:R19	2.38	No	No	0	2	4
858	A:A:Q12	A:A:R13	2.34	No	No	0	2	4
859	R:R:Q329	R:R:R326	2.34	No	No	0	7	7
860	R:R:F394	R:R:Q400	2.34	Yes	No	0	8	8
861	B:B:N125	B:B:Y111	2.33	No	No	0	4	4
862	R:R:N283	R:R:Y279	2.33	No	No	0	6	3
863	R:R:H408	R:R:R404	2.26	No	No	0	4	6
864	B:B:H62	B:B:Y105	2.18	No	Yes	0	6	6
865	B:B:F292	B:B:R314	2.14	No	Yes	0	4	8
866	R:R:R366	R:R:R370	2.13	No	Yes	0	5	5
867	R:R:R411	R:R:R414	2.13	No	No	28	4	5
868	B:B:G115	B:B:G116	2.11	No	No	0	9	9
869	R:R:G249	R:R:G250	2.11	No	No	0	7	6
870	A:A:G329	A:A:P328	2.03	No	No	0	7	1
871	R:R:G265	R:R:P267	2.03	No	Yes	0	6	9
872	R:R:R411	R:R:W407	2	No	No	28	4	5
873	R:R:R414	R:R:W407	2	No	No	28	5	5
874	B:B:C204	B:B:G185	1.96	No	No	0	7	5
875	B:B:C271	B:B:G272	1.96	No	No	0	5	4
876	A:A:A39	R:R:G250	1.95	No	No	0	5	6
877	A:A:A226	A:A:G206	1.95	No	No	0	9	8
878	B:B:A208	B:B:G202	1.95	No	No	0	6	6
879	B:B:A193	B:B:P194	1.87	No	No	0	4	4
880	R:R:A358	R:R:P359	1.87	No	No	0	6	5
881	R:R:G250	R:R:S251	1.86	No	No	0	6	7
882	B:B:G244	B:B:V276	1.84	No	No	0	5	6
883	R:R:G144	R:R:V143	1.84	No	Yes	0	8	5
884	A:A:G52	A:A:T55	1.82	No	No	0	9	9
885	B:B:G131	B:B:T128	1.82	No	No	0	4	3
886	B:B:G174	B:B:T173	1.82	No	No	0	4	5
887	B:B:G182	B:B:T181	1.82	No	No	0	6	2
888	A:A:A366	A:A:C365	1.81	No	No	0	9	8
889	B:B:A60	B:B:C103	1.81	No	No	0	7	8
890	B:B:A73	B:B:C103	1.81	No	No	0	9	8
891	B:B:G202	B:B:I229	1.76	No	No	0	6	7
892	B:B:G202	B:B:I232	1.76	No	Yes	0	6	8
893	B:B:G319	B:B:M61	1.75	No	Yes	0	5	6
894	B:B:P107	B:B:T65	1.75	No	No	0	6	1
895	G:G:P53	G:G:T52	1.75	No	No	0	8	4
896	B:B:G324	B:B:K280	1.74	No	No	0	9	1
897	B:B:A28	G:G:S31	1.71	No	No	0	4	9
898	B:B:C103	B:B:V71	1.71	No	Yes	0	8	8
899	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
900	B:B:S281	G:G:A45	1.71	No	No	0	9	4
901	R:R:G375	R:R:L137	1.71	No	No	14	5	6
902	R:R:A184	R:R:S148	1.71	No	No	0	8	9
903	R:R:A186	R:R:S189	1.71	No	No	0	6	5
904	R:R:A219	R:R:S189	1.71	No	No	0	6	5
905	R:R:G319	R:R:L322	1.71	No	No	0	8	5
906	R:R:G375	R:R:L374	1.71	No	Yes	14	5	6
907	A:A:G52	A:A:N292	1.7	No	Yes	0	9	9
908	B:B:A11	G:G:V16	1.7	No	No	0	5	7
909	B:B:G238	B:B:N237	1.7	No	Yes	0	7	5
910	A:A:D223	A:A:G225	1.68	Yes	No	0	9	9
911	A:A:D354	A:A:G353	1.68	No	No	0	3	4
912	G:G:A7	G:G:T6	1.68	No	No	0	4	3
913	R:R:A186	R:R:T223	1.68	No	No	0	6	6
914	B:B:K301	B:B:P39	1.67	Yes	No	0	5	1
915	R:R:S381	R:R:S382	1.63	No	No	0	5	9
916	A:A:S51	A:A:V247	1.62	No	Yes	0	9	7
917	B:B:S191	B:B:V200	1.62	No	Yes	0	8	6
918	G:G:A10	G:G:I9	1.62	No	No	0	2	2
919	R:R:A294	R:R:I295	1.62	No	No	0	3	3
920	G:G:A23	G:G:K20	1.61	No	No	0	8	6
921	G:G:A45	G:G:K46	1.61	No	No	0	4	1
922	B:B:S31	B:B:T29	1.6	No	No	0	1	3
923	B:B:S207	B:B:T223	1.6	No	No	0	5	2
924	R:R:V139	R:R:V143	1.6	No	Yes	23	3	5
925	R:R:V352	R:R:V356	1.6	Yes	No	0	6	6
926	R:R:T142	R:R:V139	1.59	No	No	23	7	3
927	R:R:T142	R:R:V143	1.59	No	Yes	23	7	5
928	R:R:T218	R:R:V222	1.59	No	No	0	3	5
929	B:B:A11	G:G:L15	1.58	No	No	0	5	2
930	B:B:L30	G:G:A34	1.58	No	No	0	5	6
931	R:R:A372	R:R:L369	1.58	No	No	0	5	4
932	A:A:E314	A:A:P313	1.57	No	No	0	6	6
933	A:A:E327	A:A:P328	1.57	Yes	No	0	4	1
934	B:B:A193	B:B:D195	1.54	No	No	0	4	5
935	R:R:I378	R:R:V360	1.54	No	No	0	8	4
936	R:R:C286	R:R:Q285	1.53	No	No	0	9	3
937	B:B:A21	B:B:Q17	1.52	No	No	0	4	4
938	A:A:A366	A:A:E370	1.51	No	No	0	9	4
939	A:A:G49	A:A:R265	1.5	No	No	0	8	9
940	A:A:L297	A:A:S250	1.5	No	No	0	8	6
941	B:B:L4	G:G:S8	1.5	No	No	0	4	4
942	G:G:K46	G:G:T52	1.5	No	No	0	1	4
943	R:R:G406	R:R:R405	1.5	No	Yes	0	5	8
944	B:B:N110	B:B:S108	1.49	No	No	0	4	6
945	B:B:L261	G:G:V30	1.49	Yes	No	0	5	8
946	R:R:I272	R:R:I276	1.47	No	No	0	2	3
947	A:A:N264	A:A:T263	1.46	No	No	0	9	6
948	A:A:D368	A:A:V367	1.46	No	No	0	9	9
949	B:B:D27	G:G:V30	1.46	No	No	0	8	8
950	B:B:I37	G:G:M38	1.46	Yes	No	0	2	4
951	G:G:A43	G:G:H44	1.46	No	No	0	4	6
952	R:R:I309	R:R:M305	1.46	No	No	0	6	4
953	A:A:D11	A:A:T9	1.45	No	No	0	2	6
954	R:R:I315	R:R:L312	1.43	No	No	0	5	4
955	R:R:I378	R:R:L374	1.43	No	Yes	0	8	6
956	A:A:Q59	A:A:T55	1.42	No	No	0	9	9
957	A:A:E322	A:A:T319	1.41	No	No	0	1	5
958	B:B:L14	G:G:K20	1.41	No	No	0	8	6
959	B:B:G141	B:B:W169	1.41	No	Yes	0	5	8
960	R:R:E288	R:R:T284	1.41	No	No	0	6	4
961	R:R:E363	R:R:T361	1.41	No	No	0	5	7
962	B:B:K15	B:B:N16	1.4	No	Yes	0	6	1
963	B:B:C233	B:B:F278	1.4	No	Yes	0	3	7
964	R:R:D129	R:R:I133	1.4	No	No	0	1	4
965	B:B:D212	B:B:M217	1.39	No	No	0	9	3
966	R:R:L153	R:R:L157	1.38	No	No	0	3	1
967	R:R:L318	R:R:L321	1.38	No	No	0	7	9
968	R:R:L325	R:R:L337	1.38	Yes	No	0	7	7
969	R:R:L344	R:R:L391	1.38	No	Yes	0	8	7
970	R:R:A365	R:R:R370	1.38	No	Yes	0	6	5
971	R:R:L213	R:R:N210	1.37	No	No	0	4	4
972	A:A:K28	A:A:Q29	1.36	No	No	0	4	4
973	B:B:K209	G:G:Q18	1.36	Yes	No	0	6	9
974	A:A:E299	A:A:K300	1.35	No	No	0	6	9
975	R:R:R411	R:R:S415	1.32	No	No	0	4	5
976	A:A:E10	A:A:N14	1.31	No	No	0	2	3
977	A:A:D295	A:A:Q294	1.31	No	Yes	0	9	6
978	B:B:D5	B:B:Q6	1.31	No	No	0	1	1
979	B:B:E12	B:B:N16	1.31	No	Yes	0	4	1
980	B:B:R214	B:B:V213	1.31	No	No	0	9	4
981	R:R:R136	R:R:V139	1.31	No	No	0	4	3
982	R:R:H353	R:R:K373	1.31	No	No	0	8	7
983	A:A:D368	A:A:E370	1.3	No	No	0	9	4
984	B:B:R129	B:B:T128	1.29	No	No	0	3	3
985	R:R:E362	R:R:Q364	1.27	No	No	0	5	5
986	R:R:V277	R:R:Y281	1.26	No	No	0	5	3
987	R:R:L193	R:R:R192	1.21	No	No	0	5	4
988	R:R:T301	R:R:W297	1.21	No	No	0	4	7
989	R:R:L325	R:R:R338	1.21	Yes	No	0	7	9
990	R:R:D334	R:R:R331	1.19	Yes	No	0	6	5
991	A:A:Q262	A:A:R265	1.17	No	No	0	4	9
992	B:B:Q44	R:R:R413	1.17	No	No	0	4	4
993	B:B:E130	B:B:R129	1.16	No	No	0	3	3
994	R:R:D334	R:R:Y335	1.15	Yes	No	0	6	5
995	B:B:R48	G:G:R62	1.07	Yes	No	0	7	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Y37	9.0875	4	15	4
2	A:A:R42	8.16	4	0	9
3	A:A:I207	3.3725	4	0	9
4	A:A:F219	6.832	5	16	8
5	A:A:F222	9.14	5	4	7
6	A:A:D223	4.0925	4	0	9
7	A:A:K233	7.058	5	3	9
8	A:A:W234	5.63	4	0	9
9	A:A:F238	6.45167	6	4	9
10	A:A:D240	7.5825	4	4	6
11	A:A:V247	3.585	4	17	7
12	A:A:L270	5.83	4	0	6
13	A:A:F273	5.392	5	20	9
14	A:A:W277	9.214	5	20	6
15	A:A:W281	9.538	5	4	5
16	A:A:L289	5.57	4	0	9
17	A:A:N292	4.088	5	17	9
18	A:A:Q294	4.462	5	7	6
19	A:A:P321	5.9425	4	0	5
20	A:A:E327	5.42714	7	7	4
21	A:A:D331	10.045	4	0	4
22	A:A:V334	5.425	4	0	4
23	A:A:K338	6.595	4	7	5
24	A:A:Y339	6.78	5	7	3
25	A:A:F340	9.92	4	19	7
26	A:A:R342	6.7475	4	7	4
27	A:A:E344	8.5625	4	19	5
28	A:A:F345	8.7125	4	0	8
29	A:A:C359	3.9225	4	0	5
30	A:A:F363	8.5025	4	7	5
31	A:A:R373	3.7875	4	18	5
32	A:A:F376	6.5475	4	18	8
33	A:A:R385	6.518	5	12	5
34	A:A:Y391	9.284	5	1	4
35	B:B:N16	3.7475	4	0	1
36	B:B:I37	3.4575	4	10	2
37	B:B:V40	5.012	5	10	3
38	B:B:R48	4.51	4	2	7
39	B:B:H54	9.046	5	2	9
40	B:B:K57	8.274	5	4	9
41	B:B:Y59	13.235	4	4	8
42	B:B:M61	4.492	5	2	6
43	B:B:W63	7.37	6	2	7
44	B:B:L70	7.185	4	2	5
45	B:B:V71	3.502	5	0	8
46	B:B:D76	7.51	5	15	9
47	B:B:K78	4.9725	4	0	8
48	B:B:W82	8.57	7	2	9
49	B:B:D83	7.196	5	0	8
50	B:B:S84	5.45	4	2	5
51	B:B:K89	6.21833	6	2	9
52	B:B:I93	5.79	4	0	7
53	B:B:L95	4.95	4	21	8
54	B:B:W99	7.885	8	4	9
55	B:B:Y105	4.178	5	0	6
56	B:B:Y124	6.1375	4	0	6
57	B:B:E138	6.0575	4	0	6
58	B:B:L139	5.9325	4	0	9
59	B:B:H142	7.665	4	13	9
60	B:B:Y145	7.675	6	3	8
61	B:B:R150	4.0175	4	0	6
62	B:B:F151	4.392	5	0	9
63	B:B:C166	4.0475	4	6	8
64	B:B:W169	6.66143	7	13	8
65	B:B:Q176	7.6125	4	13	4
66	B:B:F180	6.844	5	6	7
67	B:B:H183	7.624	5	6	9
68	B:B:F199	6.884	5	6	9
69	B:B:V200	5.8725	4	3	6
70	B:B:D205	6.4025	4	6	9
71	B:B:K209	7.094	5	6	6
72	B:B:W211	9.164	5	6	8
73	B:B:F222	7.8225	4	3	8
74	B:B:H225	8.19333	6	3	9
75	B:B:D228	8.196	5	3	9
76	B:B:I232	4.0775	4	3	8
77	B:B:F235	5.83571	7	5	6
78	B:B:P236	6.39	4	5	7
79	B:B:N237	5.075	4	0	5
80	B:B:F241	6.51333	6	3	6
81	B:B:D247	8.264	5	3	9
82	B:B:R251	9.6025	4	0	8
83	B:B:F253	8.424	5	3	6
84	B:B:D254	3.455	4	0	9
85	B:B:R256	5.455	4	0	9
86	B:B:L261	4.1575	4	0	5
87	B:B:Y264	6.08167	6	5	5
88	B:B:H266	7.3425	4	5	4
89	B:B:F278	4.966	5	5	7
90	B:B:R283	5.935	6	10	9
91	B:B:L285	4.792	5	5	6
92	B:B:Y289	6.38833	6	5	7
93	B:B:C294	4.1525	4	22	5
94	B:B:N295	5.72	4	5	6
95	B:B:W297	5.29833	6	5	8
96	B:B:K301	4.855	4	10	5
97	B:B:H311	8.652	5	8	9
98	B:B:R314	12.906	5	4	8
99	B:B:V327	4.1775	4	0	6
100	B:B:W332	12.618	5	4	9
101	B:B:D333	6.8	5	8	9
102	B:B:L336	4.232	5	2	7
103	B:B:K337	6.32	4	8	6
104	B:B:I338	4.46	4	2	5
105	B:B:W339	7.365	4	8	9
106	G:G:Y40	9.005	4	5	6
107	G:G:D48	7.5375	4	0	9
108	G:G:N59	6.3675	4	2	9
109	G:G:F61	6.80167	6	2	8
110	R:R:Y141	10.6275	4	9	7
111	R:R:V143	2.065	4	23	5
112	R:R:Y145	10.12	4	9	7
113	R:R:L152	5.52	5	0	9
114	R:R:F162	11.185	4	0	7
115	R:R:R169	10.575	6	1	9
116	R:R:F180	7.97333	6	1	8
117	R:R:R183	5.518	5	1	8
118	R:R:R190	6.445	6	9	6
119	R:R:L194	5.445	4	9	7
120	R:R:Y231	6.365	4	25	8
121	R:R:W233	10.094	5	1	9
122	R:R:L235	4.255	4	0	8
123	R:R:E237	6.3575	4	1	9
124	R:R:Y240	5.09429	7	1	8
125	R:R:H242	5.0925	4	26	8
126	R:R:Y259	4.385	4	0	8
127	R:R:W264	6.22857	7	1	9
128	R:R:P267	5.162	5	0	9
129	R:R:W274	4.90167	6	24	8
130	R:R:W287	9.64	4	9	9
131	R:R:K324	5.7425	4	12	9
132	R:R:L325	4.0675	4	0	7
133	R:R:D334	4.3525	4	0	6
134	R:R:V352	7.32	4	25	6
135	R:R:R370	3.86	5	0	5
136	R:R:L374	3.638	5	14	6
137	R:R:F386	7.8825	4	11	5
138	R:R:V390	6.31	4	11	5
139	R:R:L391	4.1075	4	11	7
140	R:R:F394	5.625	4	11	8
141	R:R:R405	7.755	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:D83	B:B:T86	26.9263	5.78	Yes	No	0	8	6
2	A:A:Q19	B:B:D83	26.8678	6.53	No	Yes	0	4	8
3	B:B:N88	B:B:T86	27.5618	7.31	No	No	0	7	6
4	A:A:Q19	B:B:N88	27.0266	9.24	No	No	0	4	7
5	A:A:N23	B:B:N88	54.7295	9.54	No	No	0	7	7
6	A:A:N23	B:B:K89	54.8744	8.39	No	Yes	0	7	9
7	B:B:I80	B:B:K89	27.5763	4.36	No	Yes	2	8	9
8	B:B:H54	B:B:I80	27.6074	13.26	Yes	No	2	9	8
9	B:B:H54	B:B:S74	56.4246	12.55	Yes	No	0	9	9
10	B:B:D76	B:B:S74	56.5063	10.31	Yes	No	0	9	9
11	B:B:K89	B:B:W82	28.4606	12.76	Yes	Yes	2	9	9
12	B:B:H54	B:B:W82	28.5937	3.17	Yes	Yes	2	9	9
13	A:A:Y37	B:B:D76	56.9206	3.45	Yes	Yes	15	4	9
14	A:A:R42	A:A:Y37	57.3177	16.46	Yes	Yes	0	9	4
15	A:A:F222	A:A:R42	29.2952	6.41	Yes	Yes	0	7	9
16	B:B:L70	B:B:M61	19.8991	5.65	Yes	Yes	2	5	6
17	B:B:C317	B:B:M61	58.6352	4.86	No	Yes	0	7	6
18	B:B:C317	B:B:S316	58.731	3.44	No	No	0	7	9
19	B:B:S316	B:B:W332	58.8283	4.94	No	Yes	0	9	9
20	B:B:R314	B:B:W332	91.8744	33.99	Yes	Yes	4	8	9
21	B:B:D290	B:B:R314	90.3544	9.53	No	Yes	4	6	8
22	B:B:C271	B:B:D290	90.4902	3.11	No	No	0	5	6
23	B:B:C271	B:B:D291	90.2365	6.22	No	No	0	5	8
24	B:B:D291	B:B:N293	79.6857	13.46	No	No	0	8	5
25	B:B:A309	B:B:N293	79.5456	3.13	No	No	0	3	5
26	B:B:A309	R:R:H409	79.4053	4.39	No	No	0	3	7
27	R:R:H409	R:R:R405	79.1242	11.28	No	Yes	0	7	8
28	B:B:D312	R:R:R405	78.7013	14.29	No	Yes	0	5	8
29	B:B:D312	B:B:D333	78.3823	3.99	No	Yes	8	5	9
30	B:B:D333	B:B:F335	62.5723	10.75	Yes	No	0	9	4
31	B:B:F335	B:B:R52	62.2665	5.34	No	No	0	4	7
32	B:B:R52	R:R:R163	63.302	8.53	No	No	0	7	8
33	R:R:H166	R:R:R163	63.148	6.77	No	No	0	7	8
34	R:R:H166	R:R:Y171	62.9939	10.89	No	No	0	7	6
35	R:R:F256	R:R:Y171	62.8396	8.25	No	No	0	5	6
36	R:R:F256	R:R:T168	62.6851	3.89	No	No	0	5	8
37	R:R:T168	R:R:Y240	62.3477	3.75	No	Yes	1	8	8
38	R:R:L244	R:R:Y240	22.7464	4.69	No	Yes	0	8	8
39	A:A:H387	R:R:L244	22.5542	15.43	No	No	0	8	8
40	A:A:F222	A:A:F238	22.4684	3.22	Yes	Yes	4	7	9
41	A:A:R42	A:A:V241	22.4317	2.62	Yes	No	0	9	9
42	A:A:F238	A:A:V241	22.292	2.62	Yes	No	0	9	9
43	A:A:H387	A:A:M386	17.112	10.51	No	No	0	8	3
44	A:A:M386	A:A:R356	16.9154	4.96	No	No	0	3	2
45	A:A:R356	A:A:R389	16.7195	14.93	No	No	0	2	4
46	A:A:R389	A:A:Y358	16.527	6.17	No	No	0	4	4
47	A:A:R385	A:A:Y358	12.2992	7.2	Yes	No	12	5	4
48	A:A:D381	A:A:R385	10.3699	9.53	No	Yes	12	8	5
49	A:A:D381	A:A:Y360	10.3517	10.34	No	No	0	8	8
50	A:A:F238	A:A:W234	77.024	4.01	Yes	Yes	0	9	9
51	A:A:Q227	A:A:W234	33.7841	4.38	No	Yes	0	9	9
52	A:A:Q227	B:B:N119	23.846	10.56	No	No	0	9	9
53	A:A:D240	B:B:W99	39.3111	6.7	Yes	Yes	4	6	9
54	A:A:Q227	B:B:Y145	10.1735	5.64	No	Yes	0	9	8
55	B:B:L117	B:B:M101	53.202	4.24	No	No	0	9	9
56	B:B:M101	B:B:Y145	50.8508	5.99	No	Yes	0	9	8
57	B:B:L117	B:B:W99	44.1821	3.42	No	Yes	4	9	9
58	A:A:K233	B:B:Y145	57.1429	3.58	Yes	Yes	3	9	8
59	A:A:K233	B:B:D228	51.4386	8.3	Yes	Yes	3	9	9
60	A:A:R231	A:A:W234	45.1078	8	No	Yes	0	9	9
61	A:A:L272	A:A:R231	44.7028	8.5	No	No	0	8	9
62	A:A:C237	B:B:Y59	17.0743	8.06	No	Yes	0	8	8
63	B:B:W332	B:B:Y59	34.2082	11.58	Yes	Yes	4	9	8
64	A:A:N239	B:B:W332	18.1038	6.78	No	Yes	4	8	9
65	B:B:K57	B:B:W332	35.1562	5.8	Yes	Yes	4	9	9
66	A:A:F246	A:A:L272	44.3409	7.31	No	No	0	9	8
67	A:A:F246	A:A:L289	43.9353	6.09	No	Yes	0	9	9
68	A:A:F345	A:A:L289	17.4379	9.74	Yes	Yes	0	8	9
69	A:A:L289	A:A:P361	16.602	3.28	Yes	No	0	9	5
70	A:A:P361	A:A:R342	15.7697	4.32	No	Yes	7	5	4
71	A:A:F345	A:A:L270	11.2989	9.74	Yes	Yes	0	8	6
72	R:R:I172	R:R:Y240	28.766	4.84	No	Yes	1	9	8
73	R:R:I172	R:R:W233	28.3804	4.7	No	Yes	1	9	9
74	R:R:W233	R:R:W264	26.5157	17.81	Yes	Yes	1	9	9
75	R:R:S179	R:R:W264	24.5829	4.94	No	Yes	1	9	9
76	R:R:N230	R:R:S179	24.4533	7.45	No	No	1	9	9
77	B:B:D83	B:B:V90	100	2.92	Yes	No	0	8	5
78	B:B:H91	B:B:V90	99.5189	6.92	No	No	0	5	5
79	B:B:H91	B:B:I81	99.0377	3.98	No	No	0	5	7
80	B:B:I81	B:B:V71	54.7554	3.07	No	Yes	0	7	8
81	B:B:V71	B:B:Y105	42.979	5.05	Yes	Yes	0	8	6
82	B:B:H62	B:B:Y105	82.8261	2.18	No	Yes	0	6	6
83	B:B:H62	B:B:R150	81.8349	5.64	No	Yes	0	6	6
84	B:B:L190	B:B:R150	44.917	2.43	No	Yes	0	5	6
85	B:B:F199	B:B:L190	33.9406	6.09	Yes	No	0	9	5
86	B:B:F199	B:B:W211	43.928	12.03	Yes	Yes	6	9	8
87	B:B:K209	B:B:W211	37.9621	6.96	Yes	Yes	6	6	8
88	B:B:K209	B:B:T221	33.9746	10.51	Yes	No	0	6	7
89	B:B:T221	G:G:E22	27.9874	5.64	No	No	0	7	9
90	G:G:E22	G:G:L19	25.9893	2.65	No	No	0	9	9
91	B:B:L14	G:G:L19	17.9955	6.92	No	No	0	8	9
92	B:B:I81	B:B:L126	43.8047	4.28	No	No	0	7	5
93	B:B:L126	B:B:Y105	42.8233	3.52	No	Yes	0	5	6
94	B:B:L192	B:B:R150	34.9355	2.43	No	Yes	0	5	6
95	B:B:F199	B:B:L192	33.941	4.87	Yes	No	0	9	5
96	B:B:L14	G:G:K20	13.9977	1.41	No	No	0	8	6
97	B:B:D228	B:B:S227	45.7507	5.89	Yes	No	3	9	6
98	B:B:D247	B:B:S227	44.8092	5.89	Yes	No	3	9	6
99	B:B:D247	B:B:H225	35.2865	3.78	Yes	Yes	3	9	9
100	B:B:F253	B:B:H225	24.8127	3.39	Yes	Yes	3	6	9
101	B:B:D291	B:B:Y289	16.2001	4.6	No	Yes	0	8	7
102	B:B:W297	B:B:Y289	12.8984	5.79	Yes	Yes	5	8	7
103	B:B:D333	B:B:H311	15.7559	5.04	Yes	Yes	8	9	9
104	B:B:L308	B:B:W339	15.4338	9.11	No	Yes	0	7	9
105	B:B:L308	B:B:M45	13.5077	12.72	No	No	0	7	4
106	B:B:M45	B:B:V327	13.1245	4.56	No	Yes	0	4	6
107	B:B:V327	G:G:L50	11.9842	4.47	Yes	No	0	6	9
108	B:B:S279	G:G:L50	11.6	3	No	No	0	9	9
109	B:B:S279	G:G:D48	11.2158	8.83	No	Yes	0	9	9
110	B:B:D83	B:B:R68	47.2119	16.68	Yes	No	0	8	5
111	B:B:R68	B:B:Y85	48.1332	21.61	No	No	0	5	4
112	B:B:Y85	G:G:F61	48.437	10.32	No	Yes	2	4	8
113	B:B:I338	G:G:F61	18.675	6.28	Yes	Yes	2	5	8
114	B:B:K57	B:B:Q75	17.0754	6.78	Yes	No	4	9	9
115	B:B:Q75	B:B:Y59	17.0741	22.55	No	Yes	4	9	8
116	B:B:S84	G:G:F61	37.7997	5.28	Yes	Yes	2	5	8
117	B:B:S84	B:B:W63	18.7672	7.41	Yes	Yes	2	5	7
118	B:B:I338	B:B:W63	19.0927	4.7	Yes	Yes	2	5	7
119	B:B:G144	B:B:N119	22.6042	5.09	No	No	0	8	9
120	B:B:G144	B:B:T143	22.19	3.64	No	No	0	8	5
121	B:B:D163	B:B:T143	21.7756	10.12	No	No	0	9	5
122	B:B:D163	B:B:S161	20.1164	7.36	No	No	0	9	9
123	B:B:H142	B:B:S161	19.7011	16.74	Yes	No	0	9	9
124	B:B:H142	B:B:W169	15.0935	6.35	Yes	Yes	13	9	8
125	B:B:L139	B:B:W169	12.1756	11.39	Yes	Yes	0	9	8
126	B:B:F180	B:B:F199	19.9668	7.5	Yes	Yes	6	7	9
127	B:B:F180	B:B:T178	16.002	6.49	Yes	No	0	7	4
128	B:B:L168	B:B:T178	12.0024	5.9	No	No	0	6	4
129	B:B:L168	B:B:Q156	10.0024	7.99	No	No	0	6	5
130	B:B:F241	B:B:F253	14.3268	10.72	Yes	Yes	3	6	6
131	R:R:N230	R:R:R183	17.245	8.44	No	Yes	1	9	8
132	R:R:C226	R:R:R183	16.6935	4.18	No	Yes	0	6	8
133	R:R:C226	R:R:L182	16.4966	4.76	No	No	0	6	7
134	R:R:L182	R:R:V222	16.2995	2.98	No	No	0	7	5
135	R:R:A186	R:R:V222	15.9049	3.39	No	No	0	6	5
136	R:R:A186	R:R:S189	15.5095	1.71	No	No	0	6	5
137	R:R:A219	R:R:S189	15.3116	1.71	No	No	0	6	5
138	R:R:A219	R:R:R190	15.1136	2.77	No	Yes	0	6	6
139	B:B:M61	B:B:W63	38.3942	6.98	Yes	Yes	2	6	7
140	B:B:L70	B:B:S84	19.3535	6.01	Yes	Yes	2	5	5
141	A:A:D240	A:A:N239	18.0245	4.04	Yes	No	4	6	8
142	A:A:D240	B:B:K57	18.0271	12.44	Yes	Yes	4	6	9
143	A:A:C237	B:B:W99	16.9955	5.22	No	Yes	0	8	9
144	B:B:Q75	B:B:W99	33.9666	7.67	No	Yes	4	9	9
145	A:A:F238	B:B:W99	44.7154	13.03	Yes	Yes	4	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8ITL

PDB Summary
PDB	8ITL
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GIP
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	3.23
Date	2023-10-18
D.O.I.	10.1073/pnas.2306145120

Net Summary
I_min	3.06
Number of Linked Nodes	863
Number of Links	995
Number of Hubs	141
Number of Links mediated by Hubs	539
Number of Communities	28
Number of Nodes involved in Communities	193
Number of Links involved in Communities	258

Path Summary
Number Of Nodes in MetaPath	146
Number Of Links MetaPath	145
Number of Shortest Paths	2335431
Length Of Smallest Path	3
Average Path Length	34.5783
Length of Longest Path	75
Minimum Path Strength	1.17
Average Path Strength	7.18882
Maximum Path Strength	24.49
Minimum Path Correlation	0.71
Average Path Correlation	0.982656
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.38095
Average % Of Corr. Nodes	39.6693
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.5613
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• response to stimulus • response to stress • response to wounding • response to axon injury • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • response to metal ion • response to chemical • response to calcium ion • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • negative adaptation of signaling pathway • negative regulation of signaling • negative regulation of biological process • desensitization of G protein-coupled receptor signaling pathway • regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • negative regulation of cellular process • regulation of G protein-coupled receptor signaling pathway • regulation of signaling • negative regulation of response to stimulus • negative regulation of signal transduction • regulation of response to stimulus • adaptation of signaling pathway • regulation of cell communication • metabolic process • generation of precursor metabolites and energy • response to hexose • response to monosaccharide • response to carbohydrate • response to glucose • response to oxygen-containing compound • gastric inhibitory peptide signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • developmental process • multicellular organism development • multicellular organismal process • pancreas development • endocrine system development • anatomical structure development • animal organ development • endocrine pancreas development • system development • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • cell surface receptor signaling pathway • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to lipid • response to fatty acid • response to nutrient levels • response to nutrient • positive regulation of cell communication • positive regulation of establishment of protein localization • positive regulation of insulin secretion • positive regulation of peptide hormone secretion • positive regulation of protein localization • positive regulation of biological process • positive regulation of secretion by cell • positive regulation of protein transport • positive regulation of hormone secretion • positive regulation of secretion • positive regulation of cellular process • positive regulation of peptide secretion • positive regulation of protein secretion • positive regulation of transport • positive regulation of signaling • cellular anatomical structure • membrane • cell periphery • plasma membrane • peptide hormone receptor binding • protein binding • binding • corticotropin-releasing hormone receptor binding • signaling receptor binding • G protein-coupled receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • mu-type opioid receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • ionotropic glutamate receptor binding • glutamate receptor binding • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • insulin-like growth factor receptor binding • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • intracellular anatomical structure • cytoplasm • cytoskeletal protein binding • spectrin binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to stress • response to hypoxia • response to oxygen levels • response to abiotic stimulus • cell population proliferation • phospholipase C-activating G protein-coupled receptor signaling pathway • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • organelle • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding • response to ketone • response to prostaglandin • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8ITL_Chain_A T E D Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A G E S G K N T I V K Q M S G I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V A S S Q T N R L Q A A L K L F D S I W N N K W L R D T S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N I R R V F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8ITL_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8ITL_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P48546
Sequence	>8ITL_Chain_R N E A F L D Q R L I L E R L Q V M Y T V G Y S L S L A T L L L A L L I L S L F R R L H C T R N Y I H I N L F T S F M L R A A A I L S R D R L L P N Q A L A A C R T A Q I V T Q Y C V G A N Y T W L L V E G V Y L H S L L V L V G G S E E G H F R Y Y L L L G W G A P A L F V I P W V I V R Y L Y E N T Q C W E R N E V K A I W W I I R T P I L M T I L I N F L I F I R I L G I L L S K L R T R Q M R C R D Y R L R L A R S T L F L V P L L G V H E V V F A P V T E E Q A R G A L R F A K L G F E I F L S S F Q G F L V S V L Y C F I N K E V Q S E I R R G W H H C R L R R S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8YW4	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ22	3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW4 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-		3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	2.86	2024-03-06	10.1038/s41421-024-00649-0
	8WA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		2.86	2024-03-06	10.1038/s41421-024-00649-0
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.13	2023-10-18	10.1073/pnas.2306145120
	8ITM (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.13	2023-10-18	10.1073/pnas.2306145120
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.23	2023-10-18	10.1073/pnas.2306145120
	8ITL (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.23	2023-10-18	10.1073/pnas.2306145120
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774	chim(NtGi1-Gs)/β1/γ2	3.08	2022-04-13	10.1073/pnas.2116506119
	7RBT (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774		3.08	2022-04-13	10.1073/pnas.2116506119
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/β1/γ2	3.24	2022-04-13	10.1073/pnas.2116506119
	7RA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		3.24	2022-04-13	10.1073/pnas.2116506119
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-03-02	10.1038/s41467-022-28683-0
	7VAB (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-		3.2	2022-03-02	10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/β1/γ2	3.1	2022-02-23	10.1038/s41467-022-28683-0
	7FIN (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-		3.1	2022-02-23	10.1038/s41467-022-28683-0
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/β1/γ2	2.98	2021-08-04	10.7554/eLife.68719
	7DTY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		2.98	2021-08-04	10.7554/eLife.68719

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ITL.zip

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