psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E3	L:L:Y1	12.35	Yes	Yes	1	0	0
2	L:L:G4	L:L:Y1	5.79	No	Yes	0	0	0
3	L:L:Y1	R:R:Q224	10.15	Yes	No	1	0	6
4	L:L:Y1	R:R:V227	10.09	Yes	No	1	0	6
5	L:L:Y1	R:R:Y231	2.98	Yes	Yes	1	0	8
6	L:L:Y1	R:R:W296	8.68	Yes	Yes	1	0	6
7	L:L:Y1	R:R:R300	4.12	Yes	Yes	1	0	7
8	L:L:A2	R:R:E377	7.54	No	No	0	0	7
9	L:L:A2	R:R:I378	3.25	No	No	0	0	8
10	L:L:E3	R:R:Y145	3.37	Yes	Yes	1	0	7
11	L:L:E3	R:R:R183	8.14	Yes	Yes	1	0	8
12	L:L:E3	R:R:V227	2.85	Yes	No	1	0	6
13	L:L:E3	R:R:S381	5.75	Yes	Yes	1	0	5
14	L:L:D9	L:L:T5	4.34	No	No	0	0	0
15	L:L:T5	R:R:W296	3.64	No	Yes	0	0	6
16	L:L:F6	L:L:Y10	5.16	Yes	Yes	0	0	0
17	L:L:F6	R:R:L137	7.31	Yes	No	0	0	6
18	L:L:F6	R:R:Y141	11.35	Yes	Yes	1	0	7
19	L:L:F6	R:R:L374	3.65	Yes	No	0	0	6
20	L:L:F6	R:R:I378	5.02	Yes	No	1	0	8
21	L:L:I7	R:R:R190	15.03	No	Yes	0	0	6
22	L:L:D9	L:L:S8	2.94	No	No	0	0	0
23	L:L:S8	R:R:N290	8.94	No	No	0	0	6
24	L:L:D9	R:R:R370	5.96	No	No	0	0	5
25	L:L:M14	L:L:Y10	17.96	No	Yes	0	0	0
26	L:L:Y10	R:R:L134	5.86	Yes	No	0	0	5
27	L:L:Y10	R:R:Q138	7.89	Yes	No	0	0	5
28	L:L:S11	R:R:E288	8.62	No	No	7	0	6
29	L:L:S11	R:R:R289	6.59	No	Yes	7	0	4
30	L:L:I12	R:R:R289	3.76	No	Yes	0	0	4
31	L:L:A13	R:R:Q130	6.06	No	Yes	0	0	3
32	L:L:M14	R:R:R131	6.2	No	No	0	0	3
33	L:L:D15	L:L:K16	6.91	No	No	0	0	0
34	L:L:D15	R:R:R289	7.15	No	Yes	0	0	4
35	L:L:K16	L:L:Q19	6.78	No	No	0	0	0
36	L:L:I17	R:R:R131	6.26	No	No	0	0	3
37	L:L:H18	R:R:A32	2.93	No	No	0	0	4
38	L:L:H18	R:R:Y36	7.62	No	Yes	0	0	3
39	L:L:H18	R:R:P199	9.15	No	No	0	0	3
40	L:L:N24	L:L:Q20	6.6	No	No	0	0	0
41	L:L:Q20	R:R:W90	4.38	No	Yes	0	0	4
42	L:L:F22	L:L:W25	4.01	No	Yes	0	0	0
43	L:L:F22	L:L:L26	7.31	No	No	0	0	0
44	L:L:F22	R:R:Y36	9.28	No	Yes	0	0	3
45	L:L:Q29	L:L:W25	7.67	No	Yes	0	0	0
46	L:L:W25	R:R:Y200	4.82	Yes	No	0	0	4
47	L:L:L26	R:R:W39	7.97	No	No	0	0	6
48	L:L:L26	R:R:Y68	3.52	No	Yes	0	0	5
49	L:L:L27	R:R:Y68	3.52	No	Yes	3	0	5
50	L:L:L27	R:R:R113	7.29	No	Yes	3	0	6
51	L:L:L27	R:R:H115	9	No	No	3	0	7
52	L:L:K30	R:R:Y68	10.75	Yes	Yes	3	0	5
53	L:L:K30	R:R:W71	3.48	Yes	Yes	0	0	9
54	L:L:K30	R:R:R101	7.43	Yes	Yes	3	0	8
55	L:L:K30	R:R:R113	11.14	Yes	Yes	3	0	6
56	R:R:G33	R:R:Y36	2.9	No	Yes	0	5	3
57	R:R:E34	R:R:R38	18.61	No	Yes	0	5	5
58	R:R:L35	R:R:R38	3.64	No	Yes	2	5	5
59	R:R:L35	R:R:P89	3.28	No	Yes	2	5	3
60	R:R:G202	R:R:Y36	2.9	No	Yes	0	1	3
61	R:R:A205	R:R:Y36	4	No	Yes	0	1	3
62	R:R:E40	R:R:Q37	11.47	No	No	0	3	4
63	R:R:R38	R:R:R41	10.66	Yes	No	2	5	5
64	R:R:R38	R:R:Y87	4.12	Yes	Yes	2	5	4
65	R:R:P89	R:R:R38	2.88	Yes	Yes	2	3	5
66	R:R:W39	R:R:Y87	11.58	No	Yes	0	6	4
67	R:R:E40	R:R:R44	3.49	No	No	0	3	5
68	R:R:R41	R:R:W86	10	No	No	0	5	1
69	R:R:R41	R:R:Y87	4.12	No	Yes	2	5	4
70	R:R:C70	R:R:Y42	5.38	No	Yes	2	9	7
71	R:R:S83	R:R:Y42	3.82	No	Yes	2	3	7
72	R:R:P85	R:R:Y42	9.74	No	Yes	2	8	7
73	R:R:W86	R:R:Y42	4.82	No	Yes	0	1	7
74	R:R:Y42	R:R:Y87	11.91	Yes	Yes	2	7	4
75	R:R:F65	R:R:R43	8.55	Yes	No	8	7	4
76	R:R:M67	R:R:R43	14.89	No	No	8	3	4
77	R:R:E45	R:R:W86	15.27	No	No	0	4	1
78	R:R:C46	R:R:T49	3.38	No	No	0	8	3
79	R:R:C46	R:R:C70	7.28	No	No	0	8	9
80	R:R:E48	R:R:Q47	7.65	No	No	0	3	3
81	R:R:F65	R:R:Q47	4.68	Yes	No	0	7	3
82	R:R:F65	R:R:L50	4.87	Yes	No	0	7	4
83	R:R:P56	R:R:Y73	15.3	No	No	0	1	4
84	R:R:L59	R:R:P76	8.21	No	No	0	1	4
85	R:R:C103	R:R:C61	7.28	No	No	0	9	9
86	R:R:N62	R:R:Q108	6.6	No	No	0	4	5
87	R:R:S64	R:R:W71	6.18	No	Yes	0	6	9
88	R:R:F65	R:R:M67	3.73	Yes	No	8	7	3
89	R:R:D66	R:R:Y68	11.49	No	Yes	3	9	5
90	R:R:D66	R:R:V69	5.84	No	No	3	9	5
91	R:R:D66	R:R:W71	17.87	No	Yes	0	9	9
92	R:R:V69	R:R:Y68	10.09	No	Yes	3	5	5
93	R:R:R113	R:R:Y68	4.12	Yes	Yes	3	6	5
94	R:R:C70	R:R:S83	5.16	No	No	2	9	3
95	R:R:W109	R:R:W71	25.3	No	Yes	0	9	9
96	R:R:C103	R:R:P76	3.77	No	No	0	9	4
97	R:R:L100	R:R:T79	5.9	No	No	0	4	5
98	R:R:Q102	R:R:T79	4.25	Yes	No	0	4	5
99	R:R:F98	R:R:R81	4.28	No	No	0	3	4
100	R:R:L100	R:R:R81	8.5	No	No	0	4	4
101	R:R:C84	R:R:H91	4.42	No	No	0	9	5
102	R:R:C118	R:R:C84	7.28	Yes	No	0	9	9
103	R:R:P85	R:R:Y87	5.56	No	Yes	2	8	4
104	R:R:L88	R:R:P89	4.93	No	Yes	2	5	3
105	R:R:L88	R:R:W90	12.53	No	Yes	2	5	4
106	R:R:P89	R:R:W90	5.4	Yes	Yes	2	3	4
107	R:R:N120	R:R:W90	18.08	No	Yes	0	3	4
108	R:R:A95	R:R:H91	2.93	No	No	0	5	5
109	R:R:H93	R:R:V94	4.15	No	No	0	4	3
110	R:R:H93	R:R:P121	4.58	No	No	0	4	2
111	R:R:C118	R:R:V94	3.42	Yes	No	0	9	3
112	R:R:H115	R:R:V99	9.69	No	No	0	7	7
113	R:R:L100	R:R:W112	3.42	No	Yes	0	4	5
114	R:R:Q102	R:R:R101	3.5	Yes	Yes	0	4	8
115	R:R:R101	R:R:W109	13	Yes	No	0	8	9
116	R:R:R101	R:R:R113	6.4	Yes	Yes	3	8	6
117	R:R:G110	R:R:Q102	4.93	No	Yes	0	3	4
118	R:R:Q102	R:R:W112	18.62	Yes	Yes	0	4	5
119	R:R:D106	R:R:G107	3.35	No	No	0	5	9
120	R:R:D114	R:R:W112	5.58	No	Yes	0	8	5
121	R:R:H115	R:R:R113	3.39	No	Yes	3	7	6
122	R:R:D114	R:R:T116	7.23	No	No	0	8	6
123	R:R:Q117	R:R:T116	4.25	No	No	0	4	6
124	R:R:C118	R:R:Q117	4.58	Yes	No	0	9	4
125	R:R:N120	R:R:P121	6.52	No	No	0	3	2
126	R:R:E122	R:R:N120	6.57	No	No	0	2	3
127	R:R:E122	R:R:F127	4.66	No	No	0	2	2
128	R:R:F127	R:R:Q130	4.68	No	Yes	0	2	3
129	R:R:L134	R:R:Q130	5.32	No	Yes	4	5	3
130	R:R:Q130	R:R:R370	3.5	Yes	No	4	3	5
131	R:R:F371	R:R:Q130	3.51	No	Yes	4	4	3
132	R:R:I133	R:R:L137	2.85	No	No	0	4	6
133	R:R:F371	R:R:L134	3.65	No	No	4	4	5
134	R:R:E135	R:R:V139	2.85	No	No	0	3	3
135	R:R:T142	R:R:V139	3.17	No	No	0	7	3
136	R:R:F379	R:R:M140	4.98	No	No	0	6	6
137	R:R:Y141	R:R:Y145	4.96	Yes	Yes	1	7	7
138	R:R:D191	R:R:Y141	11.49	No	Yes	0	7	7
139	R:R:I378	R:R:Y141	3.63	No	Yes	1	8	7
140	R:R:L188	R:R:T142	2.95	No	No	0	7	7
141	R:R:F383	R:R:G144	4.52	No	No	0	6	8
142	R:R:R183	R:R:Y145	4.12	Yes	Yes	1	8	7
143	R:R:A184	R:R:Y145	5.34	No	Yes	0	8	7
144	R:R:I187	R:R:Y145	7.25	No	Yes	0	7	7
145	R:R:S381	R:R:Y145	3.82	Yes	Yes	1	5	7
146	R:R:S382	R:R:Y145	10.17	No	Yes	0	9	7
147	R:R:L188	R:R:S146	3	No	No	0	7	7
148	R:R:F386	R:R:L147	4.87	Yes	No	0	5	5
149	R:R:G385	R:R:S148	3.71	No	No	0	9	9
150	R:R:A184	R:R:L149	6.3	No	No	0	8	6
151	R:R:F386	R:R:T151	7.78	Yes	No	0	5	7
152	R:R:S389	R:R:T151	3.2	No	No	0	8	7
153	R:R:F177	R:R:L152	10.96	No	No	0	9	9
154	R:R:F180	R:R:L152	3.65	Yes	No	0	8	9
155	R:R:A155	R:R:S389	3.42	No	No	0	9	8
156	R:R:A155	R:R:C393	3.61	No	No	0	9	9
157	R:R:L156	R:R:S160	3	No	No	0	6	3
158	R:R:L157	R:R:S160	3	No	No	0	1	3
159	R:R:F162	R:R:I158	3.77	No	No	0	7	8
160	R:R:I158	R:R:V399	3.07	No	Yes	0	8	9
161	R:R:I174	R:R:L159	2.85	No	No	0	7	8
162	R:R:F162	R:R:L161	10.96	No	No	0	7	3
163	R:R:E402	R:R:F162	10.49	No	No	0	8	7
164	R:R:H166	R:R:R163	4.51	No	No	0	7	8
165	R:R:E398	R:R:R164	6.98	No	No	0	9	7
166	R:R:E402	R:R:R164	8.14	No	No	0	8	7
167	R:R:L165	R:R:N170	4.12	No	No	0	9	9
168	R:R:E398	R:R:L165	9.28	No	No	0	9	9
169	R:R:H166	R:R:Y171	14.16	No	No	0	7	6
170	R:R:C167	R:R:N170	7.87	No	No	0	8	9
171	R:R:T168	R:R:Y240	11.24	No	Yes	0	8	8
172	R:R:N170	R:R:R169	10.85	No	No	0	9	9
173	R:R:H173	R:R:R169	4.51	No	No	0	9	9
174	R:R:I172	R:R:Y240	3.63	No	Yes	9	9	8
175	R:R:I172	R:R:Y259	6.04	No	No	9	9	8
176	R:R:N175	R:R:T178	2.92	No	No	0	9	3
177	R:R:N175	R:R:W233	12.43	No	Yes	0	9	9
178	R:R:F180	R:R:L176	6.09	Yes	No	0	8	9
179	R:R:L176	R:R:W233	6.83	No	Yes	0	9	9
180	R:R:L176	R:R:L234	4.15	No	No	0	9	9
181	R:R:N230	R:R:S179	8.94	No	No	0	9	9
182	R:R:F180	R:R:N230	20.54	Yes	No	0	8	9
183	R:R:F180	R:R:Q384	8.2	Yes	No	0	8	9
184	R:R:F180	R:R:G385	4.52	Yes	No	0	8	9
185	R:R:R183	R:R:V227	9.15	Yes	No	1	8	6
186	R:R:N230	R:R:R183	12.05	No	Yes	0	9	8
187	R:R:R183	R:R:Y231	12.35	Yes	Yes	1	8	8
188	R:R:R183	R:R:S381	6.59	Yes	Yes	1	8	5
189	R:R:A186	R:R:T223	5.03	No	No	0	6	6
190	R:R:A186	R:R:C226	3.61	No	No	0	6	6
191	R:R:I187	R:R:R190	5.01	No	Yes	0	7	6
192	R:R:I187	R:R:T223	3.04	No	No	0	7	6
193	R:R:D191	R:R:R190	3.57	No	Yes	0	7	6
194	R:R:Q220	R:R:R190	7.01	No	Yes	0	5	6
195	R:R:A215	R:R:L193	4.73	No	No	0	3	5
196	R:R:L194	R:R:P195	4.93	No	No	0	7	3
197	R:R:P195	R:R:P197	3.9	No	No	0	3	4
198	R:R:C286	R:R:P195	3.77	Yes	No	0	9	3
199	R:R:G198	R:R:P199	4.06	No	No	0	3	3
200	R:R:L201	R:R:Q204	18.63	No	No	0	2	4
201	R:R:D203	R:R:Q204	3.92	No	No	0	3	4
202	R:R:A207	R:R:Q204	6.06	No	No	0	2	4
203	R:R:L206	R:R:W209	4.56	No	No	0	1	4
204	R:R:L213	R:R:W209	3.42	Yes	No	0	4	4
205	R:R:L213	R:R:R217	6.07	Yes	No	0	4	8
206	R:R:C286	R:R:L213	3.17	Yes	Yes	0	9	4
207	R:R:C216	R:R:C286	7.28	No	Yes	0	9	9
208	R:R:N283	R:R:R217	12.05	No	No	1	6	8
209	R:R:R217	R:R:W287	29.99	No	Yes	1	8	9
210	R:R:I221	R:R:V275	4.61	No	No	0	5	6
211	R:R:I221	R:R:W287	4.7	No	Yes	0	5	9
212	R:R:Q224	R:R:W274	13.14	No	Yes	1	6	8
213	R:R:I299	R:R:Q224	6.86	No	No	1	7	6
214	R:R:P267	R:R:Y225	8.34	Yes	No	0	9	8
215	R:R:G228	R:R:P267	4.06	No	Yes	0	5	9
216	R:R:I303	R:R:Y231	10.88	No	Yes	1	7	8
217	R:R:I307	R:R:Y231	4.84	No	Yes	1	7	8
218	R:R:E354	R:R:Y231	11.22	Yes	Yes	1	7	8
219	R:R:L235	R:R:T232	2.95	Yes	No	0	8	6
220	R:R:G263	R:R:T232	3.64	No	No	0	9	6
221	R:R:P267	R:R:T232	3.5	Yes	No	0	9	6
222	R:R:V236	R:R:W233	8.58	No	Yes	0	8	9
223	R:R:L260	R:R:W233	5.69	No	Yes	0	6	9
224	R:R:W233	R:R:W264	7.5	Yes	No	0	9	9
225	R:R:L235	R:R:T306	8.84	Yes	No	0	8	7
226	R:R:I309	R:R:L235	8.56	No	Yes	0	6	8
227	R:R:E237	R:R:G238	4.91	No	No	0	9	9
228	R:R:E237	R:R:L349	11.93	No	Yes	0	9	9
229	R:R:L244	R:R:Y240	8.21	No	Yes	0	8	8
230	R:R:Y240	R:R:Y259	8.94	Yes	No	9	8	8
231	R:R:I317	R:R:L241	2.85	No	No	0	9	9
232	R:R:H242	R:R:V246	6.92	No	No	0	8	7
233	R:R:H242	R:R:L247	3.86	No	No	0	8	5
234	R:R:I320	R:R:L245	4.28	No	No	0	8	8
235	R:R:E252	R:R:H255	7.39	No	No	0	7	4
236	R:R:F256	R:R:Y259	3.09	No	No	0	5	8
237	R:R:F256	R:R:L260	3.65	No	No	0	5	6
238	R:R:F270	R:R:L269	7.31	No	No	0	5	4
239	R:R:F270	R:R:P302	8.67	No	No	0	5	9
240	R:R:I272	R:R:P273	3.39	No	No	0	2	4
241	R:R:R278	R:R:W274	7	No	Yes	1	8	8
242	R:R:I295	R:R:W274	3.52	Yes	Yes	1	3	8
243	R:R:I299	R:R:W274	16.44	No	Yes	1	7	8
244	R:R:I295	R:R:V277	7.68	Yes	No	0	3	5
245	R:R:R278	R:R:W287	14.99	No	Yes	1	8	9
246	R:R:I295	R:R:R278	6.26	Yes	No	1	3	8
247	R:R:L280	R:R:Y281	3.52	No	No	0	3	3
248	R:R:E282	R:R:Y281	14.59	No	No	0	5	3
249	R:R:E282	R:R:V292	2.85	No	No	0	5	6
250	R:R:N283	R:R:W287	5.65	No	Yes	1	6	9
251	R:R:R289	R:R:T284	7.76	Yes	No	0	4	4
252	R:R:C286	R:R:Q285	6.1	Yes	No	0	9	3
253	R:R:C286	R:R:E288	6.08	Yes	No	0	9	6
254	R:R:E288	R:R:R289	6.98	No	Yes	7	6	4
255	R:R:N290	R:R:W296	11.3	No	Yes	0	6	6
256	R:R:I295	R:R:V292	3.07	Yes	No	0	3	6
257	R:R:K293	R:R:W297	4.64	No	Yes	0	5	7
258	R:R:I295	R:R:I298	4.42	Yes	No	0	3	8
259	R:R:R300	R:R:W296	10	Yes	Yes	1	7	6
260	R:R:R300	R:R:W297	7	Yes	Yes	1	7	7
261	R:R:L304	R:R:W297	4.56	No	Yes	1	4	7
262	R:R:T361	R:R:W297	7.28	No	Yes	0	7	7
263	R:R:L304	R:R:R300	3.64	No	Yes	1	4	7
264	R:R:P302	R:R:T301	3.5	No	No	0	9	4
265	R:R:I303	R:R:I307	2.94	No	No	1	7	7
266	R:R:E354	R:R:I307	4.1	Yes	No	1	7	7
267	R:R:I309	R:R:L308	4.28	No	No	0	6	3
268	R:R:I309	R:R:L312	2.85	No	No	0	6	4
269	R:R:L350	R:R:N310	12.36	No	No	0	9	9
270	R:R:F311	R:R:I315	3.77	No	No	0	6	5
271	R:R:F311	R:R:V352	5.24	No	No	0	6	6
272	R:R:F311	R:R:V355	11.8	No	No	0	6	5
273	R:R:I313	R:R:L312	2.85	No	No	0	8	4
274	R:R:F314	R:R:L346	7.31	Yes	No	10	9	9
275	R:R:F314	R:R:L350	4.87	Yes	No	10	9	9
276	R:R:F314	R:R:V352	10.49	Yes	No	0	9	6
277	R:R:I317	R:R:L346	5.71	No	No	0	9	9
278	R:R:L318	R:R:T343	4.42	No	No	0	7	9
279	R:R:L321	R:R:S342	3	No	Yes	0	9	9
280	R:R:L322	R:R:R326	4.86	No	No	0	5	7
281	R:R:L322	R:R:L339	6.92	No	Yes	0	5	9
282	R:R:L325	R:R:L339	4.15	No	Yes	0	7	9
283	R:R:R336	R:R:Y335	15.43	No	No	0	6	5
284	R:R:R338	R:R:R341	17.06	No	No	0	9	9
285	R:R:L391	R:R:T345	2.95	No	No	0	7	8
286	R:R:L346	R:R:L350	6.92	No	No	10	9	9
287	R:R:P348	R:R:V347	3.53	No	No	0	9	8
288	R:R:V347	R:R:V352	4.81	No	No	0	8	6
289	R:R:L387	R:R:P348	4.93	No	No	0	6	9
290	R:R:L349	R:R:V388	2.98	Yes	No	0	9	9
291	R:R:L349	R:R:Y392	18.76	Yes	No	0	9	8
292	R:R:E354	R:R:H353	11.08	Yes	No	1	7	8
293	R:R:H353	R:R:L380	10.29	No	No	0	8	7
294	R:R:H353	R:R:Q384	6.18	No	No	1	8	9
295	R:R:E354	R:R:S381	2.87	Yes	Yes	1	7	5
296	R:R:E354	R:R:Q384	3.82	Yes	No	1	7	9
297	R:R:F357	R:R:K373	3.72	No	No	6	7	7
298	R:R:E377	R:R:F357	11.66	No	No	6	7	7
299	R:R:R366	R:R:V360	14.38	No	No	0	5	4
300	R:R:A365	R:R:K373	4.82	No	No	0	6	7
301	R:R:F371	R:R:R370	10.69	No	No	4	4	5
302	R:R:E377	R:R:K373	4.05	No	No	6	7	7
303	R:R:F379	R:R:F383	12.86	No	No	0	6	6
304	R:R:F383	R:R:S382	3.96	No	No	0	6	9
305	R:R:F386	R:R:V390	5.24	Yes	No	0	5	5
306	R:R:L391	R:R:Y392	4.69	No	No	0	7	8
307	R:R:F394	R:R:I395	3.77	No	No	0	8	5
308	R:R:N396	R:R:V399	7.39	No	Yes	0	9	9
309	R:R:E398	R:R:V399	2.85	No	Yes	0	9	9
310	R:R:E402	R:R:R405	11.63	No	Yes	0	8	8
311	R:R:G406	R:R:R405	9.01	No	Yes	5	5	8
312	R:R:H409	R:R:R405	10.16	No	Yes	5	7	8
313	R:R:C410	R:R:R405	4.18	Yes	Yes	5	4	8
314	R:R:C410	R:R:G406	3.92	Yes	No	5	4	5
315	R:R:C410	R:R:H409	2.95	Yes	No	5	4	7
316	R:R:C410	R:R:R411	4.18	Yes	No	0	4	4
317	R:R:L149	R:R:M181	2.83	No	No	0	6	7
318	R:R:L182	R:R:M181	2.83	No	No	0	7	7
319	R:R:I313	R:R:N310	2.83	No	No	0	8	9
320	R:R:E34	R:R:T31	2.82	No	No	0	5	5
321	R:R:E119	R:R:T116	2.82	No	No	0	1	6
322	R:R:G63	R:R:W71	2.81	No	Yes	0	4	9
323	R:R:G263	R:R:W233	2.81	No	Yes	0	9	9
324	R:R:L157	R:R:L161	2.77	No	No	0	1	3
325	R:R:A219	R:R:R190	2.77	No	Yes	0	6	6
326	R:R:L241	R:R:L245	2.77	No	No	0	9	8
327	R:R:L244	R:R:L245	2.77	No	No	0	8	8
328	L:L:I12	R:R:E291	2.73	No	No	0	0	4
329	R:R:E237	R:R:I172	2.73	No	No	0	9	9
330	R:R:E362	R:R:K293	2.7	No	No	0	5	5
331	R:R:A60	R:R:Y73	2.67	No	No	0	4	4
332	R:R:A268	R:R:Y225	2.67	No	No	0	3	8
333	R:R:F386	R:R:S148	2.64	Yes	No	0	5	9
334	R:R:F177	R:R:S389	2.64	No	No	0	9	8
335	R:R:F394	R:R:V390	2.62	No	No	0	8	5
336	R:R:C61	R:R:W109	2.61	No	No	0	9	9
337	R:R:D106	R:R:Q108	2.61	No	No	0	5	5
338	R:R:H173	R:R:L349	2.57	No	Yes	0	9	9
339	R:R:E45	R:R:E48	2.54	No	No	0	4	3
340	R:R:T142	R:R:Y141	2.5	No	Yes	0	7	7
341	R:R:F177	R:R:L159	2.44	No	No	0	9	8
342	R:R:F314	R:R:L318	2.44	Yes	No	0	9	7
343	R:R:L132	R:R:R136	2.43	No	No	0	3	4
344	R:R:L325	R:R:R338	2.43	No	No	0	7	9
345	R:R:L339	R:R:R336	2.43	Yes	No	0	9	6
346	R:R:L337	R:R:R341	2.43	No	No	0	7	9
347	R:R:N62	R:R:Y73	2.33	No	No	0	4	4
348	R:R:E135	R:R:R136	2.33	No	No	0	3	4
349	R:R:E253	R:R:F256	2.33	No	No	0	5	5
350	R:R:L111	R:R:W112	2.28	No	Yes	0	5	5
351	R:R:E40	R:R:W39	2.18	No	No	0	3	6
352	R:R:G265	R:R:P267	2.03	No	Yes	0	6	9
353	R:R:C118	R:R:G97	1.96	Yes	No	0	9	6
354	R:R:P55	R:R:P56	1.95	No	No	0	2	1
355	R:R:A75	R:R:P76	1.87	No	No	0	2	4
356	R:R:A229	R:R:P267	1.87	No	Yes	0	8	9
357	R:R:A266	R:R:P267	1.87	No	Yes	0	4	9
358	R:R:A358	R:R:P359	1.87	No	No	0	6	5
359	R:R:G144	R:R:V143	1.84	No	No	0	8	5
360	R:R:A74	R:R:A80	1.79	No	No	0	7	6
361	L:L:G31	L:L:K30	1.74	No	Yes	0	0	0
362	L:L:G31	L:L:K32	1.74	No	No	0	0	0
363	R:R:G107	R:R:L59	1.71	No	No	0	9	1
364	R:R:G375	R:R:L137	1.71	No	No	0	5	6
365	R:R:C226	R:R:V222	1.71	No	No	0	6	5
366	R:R:G351	R:R:L234	1.71	No	No	0	9	9
367	R:R:G263	R:R:L262	1.71	No	No	0	9	6
368	R:R:G319	R:R:L318	1.71	No	No	0	8	7
369	R:R:G375	R:R:L374	1.71	No	No	0	5	6
370	R:R:A82	R:R:V69	1.7	No	No	0	5	5
371	R:R:A82	R:R:V99	1.7	No	No	0	5	7
372	R:R:A294	R:R:V292	1.7	No	No	0	3	6
373	R:R:A358	R:R:V355	1.7	No	No	0	6	5
374	R:R:A365	R:R:V360	1.7	No	No	0	6	4
375	R:R:D106	R:R:G104	1.68	No	No	0	5	4
376	R:R:G29	R:R:Q30	1.64	No	No	0	4	5
377	R:R:S342	R:R:T343	1.6	Yes	No	0	9	9
378	R:R:S342	R:R:T345	1.6	Yes	No	0	9	8
379	R:R:C216	R:R:L193	1.59	No	No	0	9	5
380	R:R:A212	R:R:L213	1.58	No	Yes	0	6	4
381	R:R:A372	R:R:L369	1.58	No	No	0	5	4
382	R:R:E54	R:R:P55	1.57	No	No	0	2	2
383	R:R:I299	R:R:V271	1.54	No	No	0	7	6
384	R:R:I272	R:R:V275	1.54	No	No	0	2	6
385	R:R:I276	R:R:V275	1.54	No	No	0	3	6
386	R:R:I276	R:R:V277	1.54	No	No	0	3	5
387	R:R:I403	R:R:V399	1.54	No	Yes	0	5	9
388	R:R:L59	R:R:S105	1.5	No	No	0	1	1
389	R:R:L244	R:R:S243	1.5	No	No	0	8	7
390	R:R:L247	R:R:S243	1.5	No	No	0	5	7
391	R:R:L339	R:R:S342	1.5	Yes	Yes	0	9	9
392	L:L:V23	R:R:L88	1.49	No	No	0	0	5
393	R:R:N77	R:R:S105	1.49	No	No	0	7	1
394	R:R:L235	R:R:V239	1.49	Yes	No	0	8	7
395	R:R:L344	R:R:T343	1.47	No	No	0	8	9
396	R:R:P197	R:R:R196	1.44	No	No	0	4	3
397	R:R:E252	R:R:S243	1.44	No	No	0	7	7
398	R:R:L153	R:R:M181	1.41	No	No	0	3	7
399	L:L:D21	L:L:N24	1.35	No	No	0	0	0
400	R:R:D129	R:R:Q130	1.31	No	Yes	0	1	3
401	R:R:F357	R:R:V356	1.31	No	No	0	7	6
402	L:L:A28	L:L:W25	1.3	No	Yes	0	0	0
403	R:R:E34	R:R:Q30	1.27	No	No	0	5	5
404	R:R:T301	R:R:W297	1.21	No	Yes	0	4	7
405	R:R:H92	R:R:H93	1.19	No	No	0	5	4
406	R:R:Q400	R:R:R404	1.17	No	No	0	8	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:Y1	7.73714	7	1	0
2	L:L:E3	6.492	5	1	0
3	L:L:F6	6.498	5	1	0
4	L:L:Y10	9.2175	4	0	0
5	L:L:W25	4.45	4	0	0
6	L:L:K30	6.908	5	3	0
7	R:R:Y36	5.34	5	0	3
8	R:R:R38	7.982	5	2	5
9	R:R:Y42	7.134	5	2	7
10	R:R:F65	5.4575	4	8	7
11	R:R:Y68	7.24833	6	3	5
12	R:R:W71	11.128	5	0	9
13	R:R:Y87	7.458	5	2	4
14	R:R:P89	4.1225	4	2	3
15	R:R:W90	10.0975	4	2	4
16	R:R:R101	7.5825	4	3	8
17	R:R:Q102	7.825	4	0	4
18	R:R:W112	7.475	4	0	5
19	R:R:R113	6.468	5	3	6
20	R:R:C118	4.31	4	0	9
21	R:R:Q130	4.06333	6	4	3
22	R:R:Y141	6.786	5	1	7
23	R:R:Y145	5.57571	7	1	7
24	R:R:F180	8.6	5	0	8
25	R:R:R183	8.73333	6	1	8
26	R:R:R190	6.678	5	0	6
27	R:R:L213	3.56	4	0	4
28	R:R:Y231	8.454	5	1	8
29	R:R:W233	7.30667	6	0	9
30	R:R:L235	5.46	4	0	8
31	R:R:Y240	8.005	4	9	8
32	R:R:P267	3.61167	6	0	9
33	R:R:W274	10.025	4	1	8
34	R:R:C286	5.28	5	0	9
35	R:R:W287	13.8325	4	1	9
36	R:R:R289	6.448	5	7	4
37	R:R:I295	4.99	5	1	3
38	R:R:W296	8.405	4	1	6
39	R:R:W297	4.938	5	1	7
40	R:R:R300	6.19	4	1	7
41	R:R:F314	6.2775	4	10	9
42	R:R:L339	3.75	4	0	9
43	R:R:S342	1.925	4	0	9
44	R:R:L349	9.06	4	0	9
45	R:R:E354	6.618	5	1	7
46	R:R:S381	4.7575	4	1	5
47	R:R:F386	5.1325	4	0	5
48	R:R:V399	3.7125	4	0	9
49	R:R:R405	8.745	4	5	8
50	R:R:C410	3.8075	4	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E3	L:L:Y1	21.1417	12.35	Yes	Yes	1	0	0
2	L:L:Y1	R:R:Q224	63.3545	10.15	Yes	No	1	0	6
3	L:L:Y1	R:R:Y231	32.3215	2.98	Yes	Yes	1	0	8
4	L:L:E3	R:R:R183	15.0816	8.14	Yes	Yes	1	0	8
5	R:R:R183	R:R:Y231	15.6216	12.35	Yes	Yes	1	8	8
6	L:L:Y1	R:R:W296	24.3005	8.68	Yes	Yes	1	0	6
7	L:L:Y1	R:R:R300	11.1798	4.12	Yes	Yes	1	0	7
8	R:R:Y141	R:R:Y145	58.4125	4.96	Yes	Yes	1	7	7
9	L:L:D9	L:L:T5	23.7097	4.34	No	No	0	0	0
10	L:L:T5	R:R:W296	24.4835	3.64	No	Yes	0	0	6
11	L:L:F6	R:R:Y141	55.6288	11.35	Yes	Yes	1	0	7
12	L:L:F6	L:L:Y10	58.0863	5.16	Yes	Yes	0	0	0
13	L:L:D9	R:R:R370	23.7405	5.96	No	No	0	0	5
14	L:L:Y10	R:R:L134	57.5335	5.86	Yes	No	0	0	5
15	R:R:Q224	R:R:W274	59.3005	13.14	No	Yes	1	6	8
16	R:R:R278	R:R:W274	41.535	7	No	Yes	1	8	8
17	R:R:R278	R:R:W287	40.5781	14.99	No	Yes	1	8	9
18	R:R:R217	R:R:W287	32.4683	29.99	No	Yes	1	8	9
19	R:R:L213	R:R:R217	31.1363	6.07	Yes	No	0	4	8
20	R:R:C286	R:R:L213	25.6053	3.17	Yes	Yes	0	9	4
21	R:R:C286	R:R:E288	12.9485	6.08	Yes	No	0	9	6
22	R:R:E288	R:R:R289	10.0834	6.98	No	Yes	7	6	4
23	R:R:L134	R:R:Q130	56.9735	5.32	No	Yes	4	5	3
24	R:R:Q130	R:R:R370	22.6821	3.5	Yes	No	4	3	5
25	R:R:F127	R:R:Q130	78.7912	4.68	No	Yes	0	2	3
26	R:R:E122	R:R:F127	78.6154	4.66	No	No	0	2	2
27	R:R:E122	R:R:N120	78.436	6.57	No	No	0	2	3
28	R:R:N120	R:R:W90	68.5828	18.08	No	Yes	0	3	4
29	R:R:P89	R:R:W90	66.5132	5.4	Yes	Yes	2	3	4
30	R:R:P89	R:R:R38	66.3284	2.88	Yes	Yes	2	3	5
31	R:R:R38	R:R:Y87	60.6778	4.12	Yes	Yes	2	5	4
32	R:R:W39	R:R:Y87	63.1026	11.58	No	Yes	0	6	4
33	L:L:L26	R:R:W39	61.834	7.97	No	No	0	0	6
34	L:L:F22	L:L:L26	10.4821	7.31	No	No	0	0	0
35	L:L:L26	R:R:Y68	57.3813	3.52	No	Yes	0	0	5
36	R:R:R113	R:R:Y68	14.3929	4.12	Yes	Yes	3	6	5
37	L:L:K30	R:R:Y68	26.6093	10.75	Yes	Yes	3	0	5
38	L:L:K30	R:R:W71	12.5027	3.48	Yes	Yes	0	0	9
39	R:R:D66	R:R:Y68	12.8924	11.49	No	Yes	3	9	5
40	R:R:D66	R:R:W71	12.4103	17.87	No	Yes	0	9	9
41	L:L:K30	R:R:R101	13.0283	7.43	Yes	Yes	3	0	8
42	R:R:R101	R:R:R113	12.9902	6.4	Yes	Yes	3	8	6
43	R:R:W109	R:R:W71	21.39	25.3	No	Yes	0	9	9
44	R:R:C61	R:R:W109	40.8499	2.61	No	No	0	9	9
45	R:R:C103	R:R:C61	38.4759	7.28	No	No	0	9	9
46	R:R:C103	R:R:P76	36.0982	3.77	No	No	0	9	4
47	R:R:L59	R:R:P76	31.332	8.21	No	No	0	1	4
48	R:R:G107	R:R:L59	24.1555	1.71	No	No	0	9	1
49	R:R:D106	R:R:G107	21.7561	3.35	No	No	0	5	9
50	R:R:D106	R:R:Q108	16.9464	2.61	No	No	0	5	5
51	R:R:N62	R:R:Q108	14.5361	6.6	No	No	0	4	5
52	R:R:N62	R:R:Y73	12.1221	2.33	No	No	0	4	4
53	R:R:R101	R:R:W109	22.1548	13	Yes	No	0	8	9
54	R:R:N120	R:R:P121	11.4589	6.52	No	No	0	3	2
55	R:R:H93	R:R:P121	10.9297	4.58	No	No	0	4	2
56	R:R:N230	R:R:R183	96.4299	12.05	No	Yes	0	9	8
57	R:R:F180	R:R:N230	95.3679	20.54	Yes	No	0	8	9
58	R:R:F180	R:R:L176	100	6.09	Yes	No	0	8	9
59	R:R:L176	R:R:W233	97.7927	6.83	No	Yes	0	9	9
60	R:R:L260	R:R:W233	63.5466	5.69	No	Yes	0	6	9
61	R:R:F256	R:R:L260	62.7129	3.65	No	No	0	5	6
62	R:R:F256	R:R:Y259	61.042	3.09	No	No	0	5	8
63	R:R:I172	R:R:Y259	46.5169	6.04	No	No	9	9	8
64	R:R:E237	R:R:I172	46.7144	2.73	No	No	0	9	9
65	R:R:E237	R:R:L349	44.8659	11.93	No	Yes	0	9	9
66	R:R:H173	R:R:L349	28.9145	2.57	No	Yes	0	9	9
67	R:R:H173	R:R:R169	27.8924	4.51	No	No	0	9	9
68	R:R:N170	R:R:R169	26.8648	10.85	No	No	0	9	9
69	R:R:L165	R:R:N170	24.7988	4.12	No	No	0	9	9
70	R:R:E398	R:R:L165	23.7604	9.28	No	No	0	9	9
71	R:R:E398	R:R:R164	13.021	6.98	No	No	0	9	7
72	R:R:E402	R:R:R164	11.9536	8.14	No	No	0	8	7
73	R:R:Y240	R:R:Y259	13.6861	8.94	Yes	No	9	8	8
74	R:R:E354	R:R:Q384	16.6945	3.82	Yes	No	1	7	9
75	R:R:I295	R:R:W274	16.6129	3.52	Yes	Yes	1	3	8
76	R:R:G263	R:R:W233	33.4614	2.81	No	Yes	0	9	9
77	R:R:G263	R:R:T232	31.5114	3.64	No	No	0	9	6
78	R:R:L235	R:R:T232	23.7695	2.95	Yes	No	0	8	6
79	R:R:I309	R:R:L235	20.8336	8.56	No	Yes	0	6	8
80	R:R:L244	R:R:Y240	12.8054	8.21	No	Yes	0	8	8
81	R:R:R300	R:R:W297	11.5386	7	Yes	Yes	1	7	7
82	R:R:I309	R:R:L312	18.8982	2.85	No	No	0	6	4
83	R:R:I313	R:R:L312	17.9957	2.85	No	No	0	8	4
84	R:R:I313	R:R:N310	17.1584	2.83	No	No	0	8	9
85	R:R:L350	R:R:N310	16.3229	12.36	No	No	0	9	9
86	R:R:F314	R:R:L350	14.295	4.87	Yes	No	10	9	9
87	R:R:L349	R:R:Y392	17.3777	18.76	Yes	No	0	9	8
88	R:R:L391	R:R:Y392	16.3991	4.69	No	No	0	7	8
89	R:R:L391	R:R:T345	15.415	2.95	No	No	0	7	8
90	R:R:S342	R:R:T345	14.4527	1.6	Yes	No	0	9	8
91	R:R:L339	R:R:S342	10.0453	1.5	Yes	Yes	0	9	9
92	L:L:Y1	R:R:V227	15.2809	10.09	Yes	No	1	0	6
93	R:R:R183	R:R:V227	15.1921	9.15	Yes	No	1	8	6
94	R:R:E354	R:R:Y231	16.68	11.22	Yes	Yes	1	7	8
95	R:R:F180	R:R:Q384	16.5459	8.2	Yes	No	0	8	9
96	R:R:R183	R:R:Y145	51.6147	4.12	Yes	Yes	1	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y1	R:R:Q224	10.15	1	Yes	No	0	6	0	1
L:L:Y1	R:R:V227	10.09	1	Yes	No	0	6	0	1
L:L:Y1	R:R:Y231	2.98	1	Yes	Yes	0	8	0	1
L:L:Y1	R:R:W296	8.68	1	Yes	Yes	0	6	0	1
L:L:Y1	R:R:R300	4.12	1	Yes	Yes	0	7	0	1
L:L:A2	R:R:E377	7.54	0	No	No	0	7	0	1
L:L:A2	R:R:I378	3.25	0	No	No	0	8	0	1
L:L:E3	R:R:Y145	3.37	1	Yes	Yes	0	7	0	1
L:L:E3	R:R:R183	8.14	1	Yes	Yes	0	8	0	1
L:L:E3	R:R:V227	2.85	1	Yes	No	0	6	0	1
L:L:E3	R:R:S381	5.75	1	Yes	Yes	0	5	0	1
L:L:T5	R:R:W296	3.64	0	No	Yes	0	6	0	1
L:L:F6	R:R:L137	7.31	1	Yes	No	0	6	0	1
L:L:F6	R:R:Y141	11.35	1	Yes	Yes	0	7	0	1
L:L:F6	R:R:L374	3.65	1	Yes	No	0	6	0	1
L:L:F6	R:R:I378	5.02	1	Yes	No	0	8	0	1
L:L:I7	R:R:R190	15.03	0	No	Yes	0	6	0	1
L:L:S8	R:R:N290	8.94	0	No	No	0	6	0	1
L:L:D9	R:R:R370	5.96	0	No	No	0	5	0	1
L:L:Y10	R:R:L134	5.86	0	Yes	No	0	5	0	1
L:L:Y10	R:R:Q138	7.89	0	Yes	No	0	5	0	1
L:L:S11	R:R:E288	8.62	7	No	No	0	6	0	1
L:L:S11	R:R:R289	6.59	7	No	Yes	0	4	0	1
L:L:I12	R:R:R289	3.76	0	No	Yes	0	4	0	1
L:L:A13	R:R:Q130	6.06	0	No	Yes	0	3	0	1
L:L:M14	R:R:R131	6.2	0	No	No	0	3	0	1
L:L:D15	R:R:R289	7.15	0	No	Yes	0	4	0	1
L:L:I17	R:R:R131	6.26	0	No	No	0	3	0	1
L:L:H18	R:R:A32	2.93	0	No	No	0	4	0	1
L:L:H18	R:R:Y36	7.62	0	No	Yes	0	3	0	1
L:L:H18	R:R:P199	9.15	0	No	No	0	3	0	1
L:L:Q20	R:R:W90	4.38	0	No	Yes	0	4	0	1
L:L:F22	R:R:Y36	9.28	0	No	Yes	0	3	0	1
L:L:W25	R:R:Y200	4.82	0	Yes	No	0	4	0	1
L:L:L26	R:R:W39	7.97	0	No	No	0	6	0	1
L:L:L26	R:R:Y68	3.52	0	No	Yes	0	5	0	1
L:L:L27	R:R:Y68	3.52	3	No	Yes	0	5	0	1
L:L:L27	R:R:R113	7.29	3	No	Yes	0	6	0	1
L:L:L27	R:R:H115	9	3	No	No	0	7	0	1
L:L:K30	R:R:Y68	10.75	3	Yes	Yes	0	5	0	1
L:L:K30	R:R:W71	3.48	3	Yes	Yes	0	9	0	1
L:L:K30	R:R:R101	7.43	3	Yes	Yes	0	8	0	1
L:L:K30	R:R:R113	11.14	3	Yes	Yes	0	6	0	1
R:R:G33	R:R:Y36	2.9	0	No	Yes	5	3	2	1
R:R:G202	R:R:Y36	2.9	0	No	Yes	1	3	2	1
R:R:A205	R:R:Y36	4	0	No	Yes	1	3	2	1
R:R:W39	R:R:Y87	11.58	0	No	Yes	6	4	1	2
R:R:S64	R:R:W71	6.18	0	No	Yes	6	9	2	1
R:R:D66	R:R:Y68	11.49	3	No	Yes	9	5	2	1
R:R:D66	R:R:V69	5.84	3	No	No	9	5	2	2
R:R:D66	R:R:W71	17.87	3	No	Yes	9	9	2	1
R:R:V69	R:R:Y68	10.09	3	No	Yes	5	5	2	1
R:R:R113	R:R:Y68	4.12	3	Yes	Yes	6	5	1	1
R:R:W109	R:R:W71	25.3	0	No	Yes	9	9	2	1
R:R:L88	R:R:P89	4.93	2	No	Yes	5	3	1	2
R:R:L88	R:R:W90	12.53	2	No	Yes	5	4	1	1
R:R:P89	R:R:W90	5.4	2	Yes	Yes	3	4	2	1
R:R:N120	R:R:W90	18.08	0	No	Yes	3	4	2	1
R:R:H115	R:R:V99	9.69	3	No	No	7	7	1	2
R:R:Q102	R:R:R101	3.5	0	Yes	Yes	4	8	2	1
R:R:R101	R:R:W109	13	3	Yes	No	8	9	1	2
R:R:R101	R:R:R113	6.4	3	Yes	Yes	8	6	1	1
R:R:H115	R:R:R113	3.39	3	No	Yes	7	6	1	1
R:R:F127	R:R:Q130	4.68	0	No	Yes	2	3	2	1
R:R:L134	R:R:Q130	5.32	4	No	Yes	5	3	1	1
R:R:Q130	R:R:R370	3.5	4	Yes	No	3	5	1	1
R:R:F371	R:R:Q130	3.51	4	No	Yes	4	3	2	1
R:R:I133	R:R:L137	2.85	0	No	No	4	6	2	1
R:R:F371	R:R:L134	3.65	4	No	No	4	5	2	1
R:R:Y141	R:R:Y145	4.96	1	Yes	Yes	7	7	1	1
R:R:D191	R:R:Y141	11.49	0	No	Yes	7	7	2	1
R:R:I378	R:R:Y141	3.63	1	No	Yes	8	7	1	1
R:R:R183	R:R:Y145	4.12	1	Yes	Yes	8	7	1	1
R:R:A184	R:R:Y145	5.34	0	No	Yes	8	7	2	1
R:R:I187	R:R:Y145	7.25	0	No	Yes	7	7	2	1
R:R:S381	R:R:Y145	3.82	1	Yes	Yes	5	7	1	1
R:R:S382	R:R:Y145	10.17	0	No	Yes	9	7	2	1
R:R:R183	R:R:V227	9.15	1	Yes	No	8	6	1	1
R:R:N230	R:R:R183	12.05	0	No	Yes	9	8	2	1
R:R:R183	R:R:Y231	12.35	1	Yes	Yes	8	8	1	1
R:R:R183	R:R:S381	6.59	1	Yes	Yes	8	5	1	1
R:R:I187	R:R:R190	5.01	0	No	Yes	7	6	2	1
R:R:D191	R:R:R190	3.57	0	No	Yes	7	6	2	1
R:R:Q220	R:R:R190	7.01	0	No	Yes	5	6	2	1
R:R:G198	R:R:P199	4.06	0	No	No	3	3	2	1
R:R:Q224	R:R:W274	13.14	1	No	Yes	6	8	1	2
R:R:I299	R:R:Q224	6.86	1	No	No	7	6	2	1
R:R:I303	R:R:Y231	10.88	1	No	Yes	7	8	2	1
R:R:I307	R:R:Y231	4.84	1	No	Yes	7	8	2	1
R:R:E354	R:R:Y231	11.22	1	Yes	Yes	7	8	2	1
R:R:I299	R:R:W274	16.44	1	No	Yes	7	8	2	2
R:R:R289	R:R:T284	7.76	7	Yes	No	4	4	1	2
R:R:C286	R:R:E288	6.08	0	Yes	No	9	6	2	1
R:R:E288	R:R:R289	6.98	7	No	Yes	6	4	1	1
R:R:N290	R:R:W296	11.3	0	No	Yes	6	6	1	1
R:R:R300	R:R:W296	10	1	Yes	Yes	7	6	1	1
R:R:R300	R:R:W297	7	1	Yes	Yes	7	7	1	2
R:R:L304	R:R:W297	4.56	1	No	Yes	4	7	2	2
R:R:L304	R:R:R300	3.64	1	No	Yes	4	7	2	1
R:R:I303	R:R:I307	2.94	1	No	No	7	7	2	2
R:R:E354	R:R:I307	4.1	1	Yes	No	7	7	2	2
R:R:E354	R:R:S381	2.87	1	Yes	Yes	7	5	2	1
R:R:F357	R:R:K373	3.72	6	No	No	7	7	2	2
R:R:E377	R:R:F357	11.66	6	No	No	7	7	1	2
R:R:F371	R:R:R370	10.69	4	No	No	4	5	2	1
R:R:E377	R:R:K373	4.05	6	No	No	7	7	1	2
R:R:G63	R:R:W71	2.81	0	No	Yes	4	9	2	1
R:R:A219	R:R:R190	2.77	0	No	Yes	6	6	2	1
L:L:I12	R:R:E291	2.73	0	No	No	0	4	0	1
R:R:T142	R:R:Y141	2.5	0	No	Yes	7	7	2	1
R:R:E40	R:R:W39	2.18	0	No	No	3	6	2	1
R:R:G375	R:R:L137	1.71	0	No	No	5	6	2	1
R:R:G375	R:R:L374	1.71	0	No	No	5	6	2	1
L:L:V23	R:R:L88	1.49	0	No	No	0	5	0	1
R:R:D129	R:R:Q130	1.31	0	No	Yes	1	3	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7RA3_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.85
Number of Linked Nodes	361
Number of Links	406
Number of Hubs	50
Number of Links mediated by Hubs	200
Number of Communities	10
Number of Nodes involved in Communities	69
Number of Links involved in Communities	94

Path Summary
Number Of Nodes in MetaPath	97
Number Of Links MetaPath	96
Number of Shortest Paths	111855
Length Of Smallest Path	3
Average Path Length	20.5734
Length of Longest Path	54
Minimum Path Strength	1.455
Average Path Strength	7.13595
Maximum Path Strength	22.49
Minimum Path Correlation	0.7
Average Path Correlation	0.963267
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	55.6958
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.459
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • GDP binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • D1 dopamine receptor binding • dopamine receptor binding • G protein activity • molecular function regulator activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cellular process • cell division • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • regulation of molecular function • regulation of adenylate cyclase activity
Gene Ontology	Biological Process	• cellular process • cell division • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • positive regulation of autophagy • catabolic process • macroautophagy • autophagy • positive regulation of biological process • regulation of catabolic process • regulation of autophagy • positive regulation of catabolic process • positive regulation of metabolic process • regulation of macroautophagy • metabolic process • positive regulation of macroautophagy • process utilizing autophagic mechanism • regulation of metabolic process • positive regulation of cellular process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • nucleoside phosphate metabolic process • ribose phosphate metabolic process • purine nucleoside triphosphate metabolic process • GTP metabolic process • carbohydrate derivative metabolic process • primary metabolic process • nucleotide metabolic process • purine-containing compound metabolic process • nucleobase-containing compound metabolic process • purine nucleotide metabolic process • ribonucleotide metabolic process • organophosphate metabolic process • nucleobase-containing small molecule metabolic process • purine ribonucleoside triphosphate metabolic process • phosphate-containing compound metabolic process • small molecule metabolic process • nucleoside triphosphate metabolic process • purine ribonucleotide metabolic process • phosphorus metabolic process • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to nitrogen compound • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • adenylate cyclase-activating G protein-coupled receptor signaling pathway • homeostatic process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • cell-cell signaling • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytoplasm • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • Golgi apparatus subcompartment • organelle subcompartment • trans-Golgi network membrane • trans-Golgi network • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • signaling receptor binding • G protein-coupled receptor binding • gastric inhibitory polypeptide receptor binding • hormone activity • molecular function activator activity • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • glucagon receptor binding • pancreas development • endocrine system development • endocrine pancreas development • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adult locomotory behavior • behavior • adult behavior • locomotory behavior • exploration behavior • oxoacid metabolic process • ketone metabolic process • regulation of lipid metabolic process • lipid biosynthetic process • organic acid biosynthetic process • organic acid metabolic process • carboxylic acid biosynthetic process • regulation of primary metabolic process • regulation of small molecule metabolic process • small molecule metabolic process • regulation of biosynthetic process • fatty acid metabolic process • monocarboxylic acid biosynthetic process • small molecule biosynthetic process • carboxylic acid metabolic process • primary metabolic process • fatty acid biosynthetic process • regulation of ketone metabolic process • biosynthetic process • regulation of fatty acid biosynthetic process • regulation of fatty acid metabolic process • metabolic process • regulation of lipid biosynthetic process • monocarboxylic acid metabolic process • regulation of metabolic process • lipid metabolic process • sensory perception of pain • learning or memory • cognition • memory • positive regulation of cell communication • positive regulation of establishment of protein localization • positive regulation of insulin secretion • positive regulation of peptide hormone secretion • positive regulation of protein localization • positive regulation of biological process • positive regulation of secretion by cell • positive regulation of protein transport • positive regulation of hormone secretion • positive regulation of secretion • positive regulation of cellular process • positive regulation of peptide secretion • positive regulation of protein secretion • positive regulation of transport • positive regulation of signaling • response to hexose • response to monosaccharide • response to carbohydrate • response to glucose • gastric inhibitory peptide signaling pathway • response to nutrient levels • response to stress • response to starvation • endoplasmic reticulum lumen • endoplasmic reticulum • vesicle lumen • intracellular vesicle • cytoplasmic vesicle lumen • secretory granule lumen • cytoplasmic vesicle • secretory granule • secretory vesicle • amide binding • glucagon family peptide binding • peptide hormone binding • hormone binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • gastric inhibitory peptide receptor activity • peptide receptor activity • G protein-coupled peptide receptor activity • response to wounding • response to axon injury • positive regulation of cytosolic calcium ion concentration • response to metal ion • response to calcium ion • negative adaptation of signaling pathway • negative regulation of signaling • negative regulation of biological process • desensitization of G protein-coupled receptor signaling pathway • regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • negative regulation of cellular process • regulation of G protein-coupled receptor signaling pathway • negative regulation of response to stimulus • negative regulation of signal transduction • regulation of response to stimulus • adaptation of signaling pathway • generation of precursor metabolites and energy • cell surface receptor signaling pathway • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to fatty acid • response to nutrient
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • FnI-like domain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • FnI-like domain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P48546
Sequence	>7RA3_nogp_Chain_R G Q T A G E L Y Q R W E R Y R R E C Q E T L A A A E P P S G L A C N G S F D M Y V C W D Y A A P N A T A R A S C P W Y L P W H H H V A A G F V L R Q C G S D G Q W G L W R D H T Q C E N P E F L D Q R L I L E R L Q V M Y T V G Y S L S L A T L L L A L L I L S L F R R L H C T R N Y I H I N L F T S F M L R A A A I L S R D R L L P R P G P Y L G D Q A L A L W N Q A L A A C R T A Q I V T Q Y C V G A N Y T W L L V E G V Y L H S L L V L V E E G H F R Y Y L L L G W G A P A L F V I P W V I V R Y L Y E N T Q C W E R N E V K A I W W I I R T P I L M T I L I N F L I F I R I L G I L L S K L R T R D Y R L R L A R S T L T L V P L L G V H E V V F A P V T E E Q A R G A L R F A K L G F E I F L S S F Q G F L V S V L Y C F I N K E V Q S E I R R G W H H C R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	LSN3556672	chim(NtGi1-Gs)/β1/γ2	3.08	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RBT (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	LSN3556672		3.08	2022-04-13	doi.org/10.1073/pnas.2116506119
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	2.86	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		2.86	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/β1/γ2	3.1	2022-02-23	doi.org/10.1038/s41467-022-28683-0
	7FIN (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-		3.1	2022-02-23	doi.org/10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7FIY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VAB (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-		3.2	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/β1/γ2	3.24	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		3.24	2022-04-13	doi.org/10.1073/pnas.2116506119
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.23	2023-10-18	doi.org/10.1073/pnas.2306145120
	8ITL (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.23	2023-10-18	doi.org/10.1073/pnas.2306145120
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.13	2023-10-18	doi.org/10.1073/pnas.2306145120
	8ITM (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.13	2023-10-18	doi.org/10.1073/pnas.2306145120
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/β1/γ2	2.98	2021-08-04	doi.org/10.7554/eLife.68719
	7DTY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		2.98	2021-08-04	doi.org/10.7554/eLife.68719
	8YW4	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ2	3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW4 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-		3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0

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