psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D11	A:A:T9	7.23	No	No	0	1	1
2	A:A:Q12	A:A:T9	4.25	No	No	0	3	1
3	A:A:E10	A:A:R13	12.79	No	No	0	2	3
4	A:A:K17	A:A:N14	4.2	No	No	0	4	3
5	A:A:E16	A:A:R20	16.28	No	No	0	4	3
6	A:A:Q19	B:B:D83	9.14	No	Yes	2	4	8
7	A:A:Q19	B:B:T86	7.09	No	No	2	4	6
8	A:A:Q19	B:B:N88	11.88	No	No	2	4	7
9	A:A:E21	A:A:K24	12.15	No	No	0	3	4
10	A:A:E27	A:A:N23	5.26	No	No	2	6	7
11	A:A:N23	B:B:N88	12.26	No	No	2	7	7
12	A:A:N23	B:B:K89	5.6	No	Yes	2	7	9
13	A:A:I26	B:B:K89	7.27	No	Yes	0	9	9
14	A:A:I26	B:B:A92	3.25	No	No	0	9	6
15	A:A:E27	B:B:K89	9.45	No	Yes	2	6	9
16	A:A:K32	A:A:Q29	4.07	No	No	0	4	4
17	A:A:D33	A:A:Q29	3.92	No	No	0	5	4
18	A:A:D33	B:B:K78	4.15	No	Yes	0	5	8
19	A:A:R42	A:A:Y37	19.55	No	Yes	0	9	3
20	A:A:Y37	B:B:L55	7.03	Yes	No	2	3	6
21	A:A:Y37	B:B:D76	3.45	Yes	Yes	2	3	9
22	A:A:H220	A:A:T40	6.85	Yes	No	0	7	6
23	A:A:F219	A:A:H41	9.05	Yes	No	0	8	6
24	A:A:H41	A:A:T242	8.21	No	No	0	6	8
25	A:A:H41	A:A:I383	5.3	No	No	0	6	8
26	A:A:F222	A:A:R42	4.28	Yes	No	0	6	9
27	A:A:F219	A:A:L43	3.65	Yes	No	15	8	7
28	A:A:C379	A:A:L43	3.17	No	No	15	9	7
29	A:A:F238	A:A:L44	23.14	No	No	0	9	9
30	A:A:I244	A:A:L44	5.71	No	No	0	8	9
31	A:A:K53	A:A:L45	7.05	Yes	No	16	9	8
32	A:A:L45	A:A:M221	4.24	No	Yes	0	8	8
33	A:A:D223	A:A:L45	5.43	No	No	16	9	8
34	A:A:F246	A:A:L46	4.87	Yes	No	0	9	9
35	A:A:G47	A:A:K53	3.49	No	Yes	0	9	9
36	A:A:E50	A:A:K293	6.75	No	Yes	0	9	9
37	A:A:K53	A:A:S51	3.06	Yes	No	0	9	9
38	A:A:S51	A:A:V247	6.46	No	Yes	0	9	7
39	A:A:D223	A:A:K53	8.3	No	Yes	16	9	9
40	A:A:I56	A:A:M60	4.37	No	No	0	8	9
41	A:A:I56	A:A:V247	3.07	No	Yes	0	8	7
42	A:A:Q59	A:A:V367	8.6	No	No	0	9	9
43	A:A:M221	A:A:M60	5.78	Yes	No	0	8	9
44	A:A:I372	A:A:M60	5.83	No	No	0	8	9
45	A:A:F208	A:A:S205	5.28	No	No	0	6	8
46	A:A:G206	B:B:N119	5.09	No	No	0	8	9
47	A:A:F222	A:A:I207	5.02	Yes	No	1	6	9
48	A:A:I207	B:B:W99	3.52	No	Yes	1	9	9
49	A:A:E209	A:A:K211	12.15	No	No	1	9	4
50	A:A:E209	A:A:H220	7.39	No	Yes	1	9	7
51	A:A:E209	A:A:F222	11.66	No	Yes	1	9	6
52	A:A:H220	A:A:K211	18.34	Yes	No	1	7	4
53	A:A:F212	A:A:F219	10.72	No	Yes	0	9	8
54	A:A:F212	A:A:M221	3.73	No	Yes	0	9	8
55	A:A:K216	A:A:Q213	5.42	No	No	0	4	3
56	A:A:N218	A:A:Q213	9.24	No	No	0	4	3
57	A:A:I372	A:A:V214	4.61	No	No	0	8	5
58	A:A:R373	A:A:V214	3.92	Yes	No	11	6	5
59	A:A:F376	A:A:V214	3.93	Yes	No	11	9	5
60	A:A:D215	A:A:R373	5.96	No	Yes	11	5	6
61	A:A:D215	A:A:F376	7.17	No	Yes	11	5	9
62	A:A:F219	A:A:V217	5.24	Yes	No	0	8	6
63	A:A:C379	A:A:F219	6.98	No	Yes	15	9	8
64	A:A:F222	A:A:H220	3.39	Yes	Yes	1	6	7
65	A:A:F222	B:B:W99	22.05	Yes	Yes	1	6	9
66	A:A:Q227	A:A:V224	4.3	Yes	No	1	9	9
67	A:A:V224	A:A:W234	9.81	No	Yes	1	9	9
68	A:A:Q227	A:A:W234	5.48	Yes	Yes	1	9	9
69	A:A:Q227	B:B:N119	5.28	Yes	No	0	9	9
70	A:A:Q227	B:B:Y145	5.64	Yes	Yes	1	9	8
71	A:A:E230	A:A:R228	9.3	Yes	No	1	9	9
72	A:A:R228	B:B:D186	7.15	No	Yes	1	9	9
73	A:A:D229	A:A:E230	3.9	No	Yes	0	9	9
74	A:A:E230	A:A:R232	6.98	Yes	No	1	9	8
75	A:A:E230	B:B:D186	3.9	Yes	Yes	1	9	9
76	A:A:R231	A:A:W234	9	No	Yes	0	9	9
77	A:A:L272	A:A:R231	8.5	No	No	0	9	9
78	A:A:R232	B:B:C204	5.57	No	Yes	1	8	7
79	A:A:R232	B:B:D228	14.29	No	No	1	8	9
80	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
81	A:A:K233	B:B:M188	11.52	Yes	Yes	1	9	8
82	A:A:K233	B:B:C204	4.85	Yes	Yes	1	9	7
83	A:A:K233	B:B:D228	8.3	Yes	No	1	9	9
84	A:A:K233	B:B:N230	5.6	Yes	No	0	9	9
85	A:A:W234	B:B:Y145	5.79	Yes	Yes	1	9	8
86	A:A:Q236	A:A:W281	7.67	No	Yes	1	8	5
87	A:A:Q236	B:B:R314	4.67	No	Yes	1	8	8
88	A:A:C237	B:B:Y59	8.06	No	Yes	1	8	8
89	A:A:C237	B:B:M101	4.86	No	Yes	1	8	9
90	A:A:F238	A:A:V241	5.24	No	No	0	9	9
91	A:A:F238	B:B:W99	13.03	No	Yes	0	9	9
92	A:A:D240	A:A:N239	6.73	No	No	1	7	8
93	A:A:N239	B:B:K57	9.79	No	Yes	1	8	9
94	A:A:N239	B:B:W332	5.65	No	Yes	1	8	9
95	A:A:D240	B:B:K57	12.44	No	Yes	1	7	9
96	A:A:C379	A:A:T242	3.38	No	No	0	9	8
97	A:A:A243	A:A:I288	3.25	No	No	0	8	9
98	A:A:I244	A:A:T285	3.04	No	No	0	8	7
99	A:A:F290	A:A:I245	5.02	Yes	No	0	9	8
100	A:A:I245	A:A:V375	3.07	No	No	0	8	9
101	A:A:F246	A:A:V248	3.93	Yes	No	0	9	7
102	A:A:F246	A:A:L272	6.09	Yes	No	0	9	9
103	A:A:F246	A:A:F273	3.22	Yes	Yes	10	9	9
104	A:A:F246	A:A:L289	3.65	Yes	Yes	10	9	9
105	A:A:F290	A:A:V247	3.93	Yes	Yes	0	9	7
106	A:A:A269	A:A:V248	3.39	No	No	0	9	7
107	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
108	A:A:Q294	A:A:S250	5.78	Yes	No	0	6	7
109	A:A:L297	A:A:S250	7.51	No	No	0	9	7
110	A:A:K293	A:A:S251	3.06	Yes	No	17	9	9
111	A:A:L296	A:A:S251	9.01	No	No	17	7	9
112	A:A:N264	A:A:Q267	6.6	No	Yes	0	9	4
113	A:A:N264	A:A:Y311	27.91	No	No	0	9	5
114	A:A:K307	A:A:L266	9.87	Yes	No	0	5	9
115	A:A:F312	A:A:L266	3.65	Yes	No	0	8	9
116	A:A:L270	A:A:Q267	3.99	No	Yes	0	6	4
117	A:A:K271	A:A:Q267	6.78	No	Yes	0	5	4
118	A:A:F312	A:A:Q267	3.51	Yes	Yes	0	8	4
119	A:A:F345	A:A:L270	9.74	Yes	No	0	8	6
120	A:A:F273	A:A:W277	5.01	Yes	Yes	10	9	6
121	A:A:F273	A:A:V287	5.24	Yes	No	10	9	5
122	A:A:F273	A:A:L289	4.87	Yes	Yes	10	9	9
123	A:A:F273	A:A:F345	7.5	Yes	Yes	10	9	8
124	A:A:F273	A:A:I348	5.02	Yes	No	0	9	5
125	A:A:D274	A:A:N278	8.08	No	No	0	5	8
126	A:A:D274	A:A:I348	7	No	No	0	5	5
127	A:A:V287	A:A:W277	4.9	No	Yes	10	5	6
128	A:A:S349	A:A:W277	8.65	No	Yes	0	8	6
129	A:A:H357	A:A:W277	26.45	No	Yes	0	7	6
130	A:A:L282	A:A:N279	10.98	No	No	0	9	8
131	A:A:K280	A:A:W281	20.89	No	Yes	0	5	5
132	A:A:K280	A:A:R283	3.71	No	No	0	5	3
133	A:A:W281	B:B:D290	7.82	Yes	Yes	1	5	6
134	A:A:W281	B:B:R314	15.99	Yes	Yes	1	5	8
135	A:A:D354	A:A:R283	8.34	No	No	0	3	3
136	A:A:D284	A:A:R356	11.91	No	No	0	4	2
137	A:A:I382	A:A:S286	9.29	No	No	0	7	8
138	A:A:I288	A:A:Y360	3.63	No	Yes	9	9	8
139	A:A:D378	A:A:I288	12.59	No	No	9	7	9
140	A:A:F345	A:A:L289	6.09	Yes	Yes	10	8	9
141	A:A:C359	A:A:L289	3.17	No	Yes	0	6	9
142	A:A:F290	A:A:H362	4.53	Yes	No	0	9	9
143	A:A:F290	A:A:T364	11.67	Yes	No	18	9	9
144	A:A:F290	A:A:N371	7.25	Yes	No	18	9	9
145	A:A:F363	A:A:L291	3.65	Yes	No	0	5	9
146	A:A:K293	A:A:L296	5.64	Yes	No	17	9	7
147	A:A:K338	A:A:Q294	6.78	No	Yes	3	5	6
148	A:A:F363	A:A:Q294	10.54	Yes	Yes	3	5	6
149	A:A:C365	A:A:Q294	4.58	No	Yes	0	7	6
150	A:A:C365	A:A:D295	6.22	No	No	0	7	9
151	A:A:A298	A:A:V334	3.39	No	No	0	5	4
152	A:A:E299	A:A:L302	3.98	No	No	0	5	2
153	A:A:K300	A:A:K305	5.75	No	No	0	9	3
154	A:A:K300	A:A:K307	5.75	No	Yes	0	9	5
155	A:A:V301	A:A:V334	3.21	No	No	0	7	4
156	A:A:D331	A:A:L302	4.07	No	No	0	4	2
157	A:A:A303	A:A:K305	3.21	No	No	0	4	3
158	A:A:I308	A:A:S306	3.1	Yes	No	0	7	7
159	A:A:D310	A:A:S306	10.31	No	No	0	3	7
160	A:A:K307	A:A:Y311	7.17	Yes	No	0	5	5
161	A:A:F315	A:A:I308	6.28	Yes	Yes	3	6	7
162	A:A:A337	A:A:I308	4.87	No	Yes	0	7	7
163	A:A:F340	A:A:I308	5.02	Yes	Yes	3	6	7
164	A:A:E309	A:A:F315	8.16	No	Yes	0	4	6
165	A:A:F312	A:A:Y311	6.19	Yes	No	0	8	5
166	A:A:E314	A:A:F312	7	Yes	Yes	3	5	8
167	A:A:F312	A:A:F340	6.43	Yes	Yes	3	8	6
168	A:A:E314	A:A:P313	3.14	Yes	No	0	5	6
169	A:A:E314	A:A:F340	5.83	Yes	Yes	3	5	6
170	A:A:E314	A:A:E344	6.34	Yes	No	3	5	6
171	A:A:F315	A:A:Y318	5.16	Yes	Yes	3	6	7
172	A:A:F315	A:A:R336	17.1	Yes	No	3	6	5
173	A:A:F315	A:A:F340	15	Yes	Yes	3	6	6
174	A:A:P321	A:A:Y318	4.17	Yes	Yes	3	4	7
175	A:A:R336	A:A:Y318	4.12	No	Yes	3	5	7
176	A:A:F340	A:A:Y318	12.38	Yes	Yes	3	6	7
177	A:A:D343	A:A:Y318	9.2	No	Yes	3	3	7
178	A:A:P321	A:A:T320	3.5	Yes	No	0	4	1
179	A:A:R336	A:A:T320	5.17	No	No	0	5	1
180	A:A:P321	A:A:Y339	8.34	Yes	Yes	3	4	3
181	A:A:D343	A:A:P321	3.22	No	Yes	3	3	4
182	A:A:A324	A:A:P326	3.74	No	No	0	3	1
183	A:A:E327	A:A:P328	9.43	No	No	0	3	2
184	A:A:E327	A:A:K338	5.4	No	No	0	3	5
185	A:A:D331	A:A:P332	6.44	No	No	0	4	3
186	A:A:D331	A:A:R333	13.1	No	No	0	4	5
187	A:A:F363	A:A:K338	11.17	Yes	No	3	5	5
188	A:A:R342	A:A:Y339	7.2	Yes	Yes	3	5	3
189	A:A:F363	A:A:Y339	6.19	Yes	Yes	3	5	3
190	A:A:E344	A:A:F340	10.49	No	Yes	3	6	6
191	A:A:D343	A:A:R342	5.96	No	Yes	3	3	5
192	A:A:L346	A:A:R342	6.07	No	Yes	3	3	5
193	A:A:P361	A:A:R342	5.76	No	Yes	3	4	5
194	A:A:F363	A:A:R342	7.48	Yes	Yes	3	5	5
195	A:A:E344	A:A:R347	12.79	No	No	0	6	4
196	A:A:L346	A:A:P361	6.57	No	No	3	3	4
197	A:A:S349	A:A:T350	4.8	No	No	0	8	4
198	A:A:C359	A:A:S349	5.16	No	No	0	6	8
199	A:A:G355	A:A:H357	3.18	No	No	0	1	7
200	A:A:R356	A:A:R389	25.59	No	No	0	2	5
201	A:A:Y358	A:A:Y360	15.89	No	Yes	9	4	8
202	A:A:R385	A:A:Y358	3.09	Yes	No	9	6	4
203	A:A:Y358	R:R:R328	12.35	No	No	9	4	6
204	A:A:D378	A:A:Y360	14.94	No	Yes	9	7	8
205	A:A:D381	A:A:Y360	8.05	No	Yes	9	8	8
206	A:A:I382	A:A:Y360	9.67	No	Yes	0	7	8
207	A:A:H362	A:A:R374	9.03	No	Yes	0	9	4
208	A:A:D378	A:A:H362	10.08	No	No	0	7	9
209	A:A:N371	A:A:T364	4.39	No	No	18	9	9
210	A:A:R374	A:A:T364	9.06	Yes	No	0	4	9
211	A:A:D368	A:A:S366	4.42	No	No	0	9	9
212	A:A:R374	A:A:S366	3.95	Yes	No	0	4	9
213	A:A:E370	A:A:R374	8.14	No	Yes	0	5	4
214	A:A:F376	A:A:R373	3.21	Yes	Yes	11	9	6
215	A:A:N377	A:A:R373	6.03	No	Yes	11	5	6
216	A:A:F376	A:A:N377	3.62	Yes	No	11	9	5
217	A:A:I383	A:A:R380	5.01	No	No	0	8	7
218	A:A:Q384	A:A:R380	12.85	No	No	0	6	7
219	A:A:R380	R:R:V248	6.54	No	No	0	7	7
220	A:A:D381	A:A:R385	10.72	No	Yes	9	8	6
221	A:A:D381	R:R:K324	11.06	No	No	9	8	9
222	A:A:H387	A:A:I383	5.3	Yes	No	0	8	8
223	A:A:Q384	R:R:K324	5.42	No	No	0	6	9
224	A:A:R385	R:R:K324	7.43	Yes	No	9	6	9
225	A:A:R385	R:R:R328	4.26	Yes	No	9	6	6
226	A:A:H387	A:A:M386	5.25	Yes	No	19	8	3
227	A:A:M386	A:A:Q390	8.16	No	No	19	3	5
228	A:A:H387	A:A:Q390	3.71	Yes	No	19	8	5
229	A:A:H387	R:R:L244	14.14	Yes	No	0	8	8
230	A:A:L388	A:A:L393	4.15	No	No	0	8	9
231	A:A:L388	R:R:L245	6.92	No	No	0	8	8
232	A:A:L394	A:A:R389	3.64	No	No	0	7	5
233	A:A:Y391	R:R:R169	11.32	No	Yes	0	4	9
234	A:A:Y391	R:R:L241	14.07	No	No	0	4	9
235	A:A:L393	R:R:F345	3.65	No	Yes	0	9	8
236	B:B:E3	B:B:L7	3.98	No	No	0	5	8
237	B:B:L4	B:B:R8	7.29	Yes	No	0	4	3
238	B:B:L4	G:G:S8	7.51	Yes	No	0	4	4
239	B:B:L4	G:G:I9	5.71	Yes	No	0	4	2
240	B:B:L7	B:B:Q6	5.32	No	No	0	8	1
241	B:B:L7	G:G:A12	3.15	No	No	0	8	5
242	B:B:E12	B:B:Q9	11.47	Yes	No	0	4	3
243	B:B:E10	B:B:L14	5.3	No	No	0	8	8
244	B:B:E12	B:B:Q13	14.02	Yes	No	0	4	1
245	B:B:E12	B:B:N16	3.94	Yes	No	0	4	1
246	B:B:L14	B:B:Q17	3.99	No	No	0	8	4
247	B:B:L14	G:G:L19	4.15	No	No	0	8	9
248	B:B:N16	B:B:R19	6.03	No	No	0	1	4
249	B:B:I18	B:B:R22	5.01	No	No	0	7	6
250	B:B:I18	G:G:A23	3.25	No	No	0	7	8
251	B:B:D258	B:B:R22	10.72	Yes	No	0	7	6
252	B:B:Q259	B:B:R22	3.5	Yes	No	0	6	6
253	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
254	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
255	B:B:C25	G:G:K29	4.85	No	No	0	3	4
256	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
257	B:B:D27	G:G:K29	8.3	No	No	0	8	4
258	B:B:D27	G:G:S31	8.83	No	No	0	8	9
259	B:B:Q32	B:B:T29	12.76	No	No	0	1	3
260	B:B:L30	B:B:M262	7.07	No	Yes	0	5	4
261	B:B:M262	B:B:S31	3.07	Yes	No	0	4	1
262	B:B:K301	B:B:T34	4.5	No	No	0	5	5
263	B:B:N35	B:B:N36	9.54	No	No	0	1	1
264	B:B:I37	B:B:R283	3.76	No	Yes	0	2	9
265	B:B:D38	B:B:P39	6.44	No	No	0	1	1
266	B:B:I43	B:B:V40	3.07	No	No	0	3	3
267	B:B:D298	B:B:V40	10.22	No	No	0	9	3
268	B:B:Q44	B:B:R42	4.67	No	No	0	4	2
269	B:B:A305	B:B:I43	3.25	No	No	0	4	3
270	B:B:L308	B:B:M45	9.9	No	No	0	7	4
271	B:B:M45	B:B:V327	3.04	No	Yes	0	4	6
272	B:B:R46	B:B:R48	9.6	No	No	0	5	7
273	B:B:T47	B:B:W339	3.64	No	Yes	0	3	9
274	B:B:N340	B:B:R48	3.62	Yes	No	0	9	7
275	B:B:I338	B:B:R49	3.76	No	No	0	5	7
276	B:B:R52	B:B:T50	10.35	No	No	0	7	3
277	B:B:K337	B:B:T50	7.51	No	No	0	6	3
278	B:B:L51	B:B:W82	21.64	No	Yes	0	9	9
279	B:B:L336	B:B:L51	6.92	No	No	0	7	9
280	B:B:F335	B:B:R52	5.34	No	No	0	4	7
281	B:B:R52	R:R:R163	14.93	No	No	0	7	8
282	B:B:G53	B:B:W82	4.22	No	Yes	2	9	9
283	B:B:G53	B:B:K89	3.49	No	Yes	2	9	9
284	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
285	B:B:H54	B:B:S72	8.37	Yes	No	2	9	9
286	B:B:H54	B:B:S74	16.74	Yes	No	2	9	9
287	B:B:H54	B:B:K78	5.24	Yes	Yes	2	9	8
288	B:B:H54	B:B:I80	13.26	Yes	No	2	9	8
289	B:B:H54	B:B:W82	3.17	Yes	Yes	2	9	9
290	B:B:D76	B:B:L55	10.86	Yes	No	2	9	6
291	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
292	B:B:K57	B:B:Y59	9.55	Yes	Yes	1	9	8
293	B:B:K57	B:B:Q75	8.14	Yes	No	1	9	9
294	B:B:K57	B:B:W332	9.28	Yes	Yes	1	9	9
295	B:B:Q75	B:B:Y59	22.55	No	Yes	1	9	8
296	B:B:M101	B:B:Y59	3.59	Yes	Yes	1	9	8
297	B:B:W332	B:B:Y59	8.68	Yes	Yes	1	9	8
298	B:B:A60	B:B:C103	3.61	No	No	0	7	8
299	B:B:C317	B:B:M61	9.73	No	No	0	7	6
300	B:B:A328	B:B:M61	3.22	No	No	0	5	6
301	B:B:H62	B:B:Y105	3.27	No	No	0	6	6
302	B:B:H62	B:B:R150	9.03	No	No	0	6	6
303	B:B:L70	B:B:W63	10.25	No	Yes	0	5	7
304	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
305	B:B:T321	B:B:W63	10.92	Yes	Yes	0	7	7
306	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
307	B:B:D66	B:B:L69	5.43	No	No	0	8	5
308	B:B:S67	B:B:T321	6.4	No	Yes	21	5	7
309	B:B:D322	B:B:S67	4.42	No	No	0	1	5
310	B:B:D323	B:B:S67	10.31	No	No	21	7	5
311	B:B:D83	B:B:R68	17.87	Yes	No	0	8	5
312	B:B:R68	B:B:Y85	24.69	No	No	0	5	4
313	B:B:D83	B:B:L69	4.07	Yes	No	0	8	5
314	B:B:L70	B:B:W82	6.83	No	Yes	0	5	9
315	B:B:L79	B:B:V71	4.47	Yes	No	0	7	8
316	B:B:I81	B:B:V71	4.61	No	No	0	7	8
317	B:B:S72	B:B:W82	6.18	No	Yes	2	9	9
318	B:B:L336	B:B:S72	4.5	No	No	0	7	9
319	B:B:A73	B:B:V100	5.09	No	No	0	9	9
320	B:B:A73	B:B:C103	3.61	No	No	0	9	8
321	B:B:D76	B:B:S74	7.36	Yes	No	2	9	9
322	B:B:K78	B:B:S74	3.06	Yes	No	2	8	9
323	B:B:Q75	B:B:W99	5.48	No	Yes	1	9	9
324	B:B:D76	B:B:K78	6.91	Yes	Yes	2	9	8
325	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
326	B:B:G77	B:B:S98	3.71	No	No	0	8	8
327	B:B:I80	B:B:K78	4.36	No	Yes	2	8	8
328	B:B:L79	B:B:L95	4.15	Yes	Yes	13	7	8
329	B:B:C103	B:B:L79	3.17	No	Yes	0	8	7
330	B:B:C114	B:B:L79	3.17	Yes	Yes	13	8	7
331	B:B:I80	B:B:W82	14.09	No	Yes	2	8	9
332	B:B:I81	B:B:V90	3.07	No	No	0	7	5
333	B:B:I81	B:B:L126	4.28	No	No	0	7	5
334	B:B:K89	B:B:W82	12.76	Yes	Yes	2	9	9
335	B:B:D83	B:B:T86	5.78	Yes	No	2	8	6
336	B:B:S84	G:G:F61	5.28	No	Yes	0	5	8
337	B:B:Y85	G:G:P60	11.13	No	No	0	4	9
338	B:B:Y85	G:G:F61	7.22	No	Yes	0	4	8
339	B:B:N88	B:B:T86	8.77	No	No	2	7	6
340	B:B:H91	B:B:V90	5.54	No	No	0	5	5
341	B:B:H91	B:B:V133	4.15	No	No	0	5	4
342	B:B:I93	B:B:P94	3.39	No	No	0	7	5
343	B:B:I93	B:B:Y124	9.67	No	No	0	7	6
344	B:B:I93	B:B:V133	12.29	No	No	0	7	4
345	B:B:L95	B:B:V100	4.47	Yes	No	13	8	9
346	B:B:C114	B:B:L95	6.35	Yes	Yes	13	8	8
347	B:B:L95	B:B:Y124	4.69	Yes	No	0	8	6
348	B:B:E138	B:B:R96	5.82	Yes	No	0	6	6
349	B:B:D118	B:B:S97	11.78	No	No	0	9	8
350	B:B:L117	B:B:W99	4.56	No	Yes	0	9	9
351	B:B:C114	B:B:V100	3.42	Yes	No	13	8	9
352	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
353	B:B:M101	B:B:Y145	7.18	Yes	Yes	1	9	8
354	B:B:C148	B:B:T102	3.38	No	No	0	6	8
355	B:B:C149	B:B:T102	6.76	No	No	0	8	8
356	B:B:G109	B:B:Y105	5.79	No	No	0	5	6
357	B:B:A106	B:B:F151	8.32	No	Yes	0	6	9
358	B:B:N110	B:B:S108	5.96	No	No	0	4	6
359	B:B:D154	B:B:S108	10.31	No	No	0	6	6
360	B:B:K127	B:B:N110	5.6	No	No	0	4	4
361	B:B:I123	B:B:Y111	3.63	No	Yes	22	6	4
362	B:B:N125	B:B:Y111	15.12	No	Yes	0	4	4
363	B:B:S136	B:B:Y111	5.09	No	Yes	22	4	4
364	B:B:D154	B:B:Y111	6.9	No	Yes	0	6	4
365	B:B:L126	B:B:V112	4.47	No	No	0	5	8
366	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
367	B:B:C114	B:B:G115	3.92	Yes	No	0	8	9
368	B:B:G115	B:B:L146	3.42	No	No	0	9	7
369	B:B:D118	B:B:I120	5.6	No	No	0	9	6
370	B:B:G144	B:B:N119	3.39	No	No	0	8	9
371	B:B:E138	B:B:I120	5.47	Yes	No	0	6	6
372	B:B:C121	B:B:L139	4.76	No	No	0	8	9
373	B:B:C121	B:B:L146	3.17	No	No	0	8	7
374	B:B:E138	B:B:S122	4.31	Yes	No	0	6	8
375	B:B:I123	B:B:S136	3.1	No	No	22	6	4
376	B:B:I123	B:B:I171	5.89	No	No	0	6	6
377	B:B:V135	B:B:Y124	6.31	No	No	0	4	6
378	B:B:N125	B:B:T128	4.39	No	No	0	4	3
379	B:B:G131	B:B:T128	3.64	No	No	0	4	3
380	B:B:E130	B:B:R129	3.49	No	No	0	3	3
381	B:B:R129	B:B:R134	4.26	No	No	0	3	3
382	B:B:E138	B:B:V135	4.28	Yes	No	0	6	4
383	B:B:L139	B:B:W169	12.53	No	Yes	0	9	8
384	B:B:H142	B:B:T159	5.48	Yes	Yes	6	9	9
385	B:B:H142	B:B:S161	15.34	Yes	No	6	9	9
386	B:B:H142	B:B:W169	7.41	Yes	Yes	6	9	8
387	B:B:H142	B:B:Q176	4.95	Yes	Yes	6	9	4
388	B:B:G144	B:B:T143	3.64	No	No	6	8	5
389	B:B:D163	B:B:T143	5.78	Yes	No	6	9	5
390	B:B:D163	B:B:G144	3.35	Yes	No	6	9	8
391	B:B:G162	B:B:Y145	8.69	No	Yes	0	9	8
392	B:B:D186	B:B:Y145	8.05	Yes	Yes	1	9	8
393	B:B:M188	B:B:Y145	7.18	Yes	Yes	1	8	8
394	B:B:L146	B:B:T159	4.42	No	Yes	0	7	9
395	B:B:S147	B:B:S160	3.26	No	No	0	9	6
396	B:B:M188	B:B:S147	4.6	Yes	No	0	8	9
397	B:B:C148	B:B:R150	4.18	No	No	0	6	6
398	B:B:C148	B:B:L190	3.17	No	No	0	6	5
399	B:B:C149	B:B:T159	3.38	No	Yes	0	8	9
400	B:B:L192	B:B:R150	3.64	No	No	0	5	6
401	B:B:F151	B:B:I157	3.77	Yes	Yes	0	9	7
402	B:B:L152	B:B:V213	4.47	No	No	0	3	4
403	B:B:D170	B:B:N155	6.73	No	No	0	9	3
404	B:B:E172	B:B:N155	5.26	No	No	0	6	3
405	B:B:L168	B:B:Q156	7.99	No	No	0	6	5
406	B:B:I157	B:B:T159	3.04	Yes	Yes	6	7	9
407	B:B:I157	B:B:W169	3.52	Yes	Yes	6	7	8
408	B:B:I157	B:B:I171	4.42	Yes	No	0	7	6
409	B:B:L190	B:B:V158	4.47	No	No	7	5	5
410	B:B:L192	B:B:V158	4.47	No	No	7	5	5
411	B:B:F199	B:B:V158	5.24	Yes	No	7	9	5
412	B:B:T159	B:B:W169	8.49	Yes	Yes	6	9	8
413	B:B:S160	B:B:V187	6.46	No	No	0	6	9
414	B:B:D163	B:B:S161	8.83	Yes	No	6	9	9
415	B:B:S161	B:B:T165	3.2	No	No	6	9	7
416	B:B:D163	B:B:T165	10.12	Yes	No	6	9	7
417	B:B:T165	B:B:T181	4.71	No	No	0	7	2
418	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
419	B:B:C166	B:B:V187	3.42	No	No	0	8	9
420	B:B:C166	B:B:S201	3.44	No	No	0	8	9
421	B:B:A167	B:B:W169	5.19	No	Yes	6	4	8
422	B:B:A167	B:B:Q176	7.58	No	Yes	6	4	4
423	B:B:L168	B:B:T178	4.42	No	No	0	6	4
424	B:B:Q176	B:B:W169	16.43	Yes	Yes	6	4	8
425	B:B:D170	B:B:T173	5.78	No	No	0	9	5
426	B:B:Q175	B:B:T173	14.17	No	No	0	4	5
427	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
428	B:B:T177	B:B:T178	3.14	No	No	0	4	4
429	B:B:F180	B:B:T178	3.89	Yes	No	0	7	4
430	B:B:F180	B:B:F199	8.57	Yes	Yes	7	7	9
431	B:B:F180	B:B:W211	16.04	Yes	Yes	7	7	8
432	B:B:H183	B:B:V187	4.15	Yes	No	0	9	9
433	B:B:H183	B:B:S201	6.97	Yes	No	0	9	9
434	B:B:A203	B:B:H183	8.78	No	Yes	7	8	9
435	B:B:D205	B:B:H183	8.82	Yes	Yes	7	9	9
436	B:B:H183	B:B:K209	17.03	Yes	Yes	7	9	6
437	B:B:D205	B:B:T184	8.67	Yes	No	0	9	3
438	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
439	B:B:C204	B:B:M188	3.24	Yes	Yes	1	7	8
440	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
441	B:B:F199	B:B:L190	7.31	Yes	No	7	9	5
442	B:B:C233	B:B:S191	3.44	No	No	0	3	8
443	B:B:F234	B:B:S191	7.93	No	No	0	5	8
444	B:B:F199	B:B:L192	4.87	Yes	No	7	9	5
445	B:B:A193	B:B:D195	3.09	No	No	0	4	5
446	B:B:A193	B:B:F234	8.32	No	No	0	4	5
447	B:B:G238	B:B:P194	4.06	No	No	0	7	4
448	B:B:D195	B:B:R197	8.34	No	No	0	5	5
449	B:B:R197	B:B:R214	24.52	No	No	0	5	9
450	B:B:L198	B:B:L210	5.54	No	No	0	3	5
451	B:B:F199	B:B:W211	9.02	Yes	Yes	7	9	8
452	B:B:I232	B:B:V200	6.14	Yes	No	4	8	6
453	B:B:F234	B:B:V200	13.11	No	No	0	5	6
454	B:B:F241	B:B:V200	6.55	Yes	No	4	6	6
455	B:B:S201	B:B:W211	8.65	No	Yes	0	9	8
456	B:B:A203	B:B:D205	4.63	No	Yes	7	8	9
457	B:B:C204	B:B:D228	10.89	Yes	No	1	7	9
458	B:B:D205	B:B:S207	10.31	Yes	No	0	9	5
459	B:B:S207	B:B:T221	3.2	No	No	0	5	7
460	B:B:K209	B:B:W211	9.28	Yes	Yes	7	6	8
461	B:B:C218	B:B:K209	6.47	No	Yes	7	5	6
462	B:B:K209	B:B:T221	13.51	Yes	No	0	6	7
463	B:B:L210	B:B:Q220	6.65	No	Yes	4	5	7
464	B:B:L210	B:B:L255	5.54	No	No	4	5	6
465	B:B:C218	B:B:W211	7.84	No	Yes	7	5	8
466	B:B:D212	B:B:E215	11.69	No	No	0	9	3
467	B:B:D212	B:B:R219	14.29	No	No	0	9	5
468	B:B:R214	B:B:V213	3.92	No	No	0	9	4
469	B:B:E215	B:B:G216	4.91	No	No	0	3	4
470	B:B:E215	B:B:M217	10.83	No	No	0	3	3
471	B:B:C218	G:G:Q18	6.1	No	No	0	5	9
472	B:B:F222	B:B:Q220	7.03	Yes	Yes	4	8	7
473	B:B:L255	B:B:Q220	5.32	No	Yes	4	6	7
474	B:B:D258	B:B:Q220	6.53	Yes	Yes	4	7	7
475	B:B:Q220	G:G:E22	7.65	Yes	No	4	7	9
476	B:B:Q220	G:G:I25	4.12	Yes	No	0	7	2
477	B:B:F222	B:B:F241	7.5	Yes	Yes	4	8	6
478	B:B:F222	B:B:F253	9.65	Yes	Yes	4	8	6
479	B:B:D258	B:B:F222	5.97	Yes	Yes	4	7	8
480	B:B:E260	B:B:G224	3.27	No	No	0	6	6
481	B:B:H225	B:B:I229	7.95	Yes	No	4	9	7
482	B:B:H225	B:B:T243	8.21	Yes	Yes	4	9	8
483	B:B:H225	B:B:S245	11.16	Yes	No	4	9	9
484	B:B:D247	B:B:H225	6.3	Yes	Yes	4	9	9
485	B:B:H225	B:B:R251	15.8	Yes	Yes	0	9	8
486	B:B:D247	B:B:E226	12.99	Yes	No	0	9	3
487	B:B:S227	B:B:S245	3.26	No	No	4	6	9
488	B:B:D247	B:B:S227	5.89	Yes	No	4	9	6
489	B:B:I229	B:B:T243	3.04	No	Yes	4	7	8
490	B:B:D246	B:B:N230	5.39	No	No	0	9	9
491	B:B:A231	B:B:V276	3.39	No	No	0	5	6
492	B:B:F241	B:B:I232	5.02	Yes	Yes	4	6	8
493	B:B:I232	B:B:T243	3.04	Yes	Yes	4	8	8
494	B:B:F235	B:B:P236	10.11	Yes	Yes	12	6	7
495	B:B:F235	B:B:F278	9.65	Yes	Yes	12	6	7
496	B:B:F235	B:B:G282	6.02	Yes	No	12	6	9
497	B:B:F235	G:G:L37	9.74	Yes	No	0	6	7
498	B:B:F235	G:G:Y40	6.19	Yes	Yes	12	6	6
499	B:B:F235	G:G:C41	4.19	Yes	No	0	6	7
500	B:B:F278	B:B:P236	4.33	Yes	Yes	12	7	7
501	B:B:G282	B:B:P236	4.06	No	Yes	12	9	7
502	B:B:P236	G:G:Y40	4.17	Yes	Yes	12	7	6
503	B:B:N237	B:B:N239	8.17	No	No	0	5	2
504	B:B:N237	G:G:Y40	13.96	No	Yes	0	5	6
505	B:B:N239	B:B:R256	9.64	No	Yes	0	2	9
506	B:B:F241	B:B:F253	11.79	Yes	Yes	4	6	6
507	B:B:F253	B:B:T243	9.08	Yes	Yes	4	6	8
508	B:B:G244	B:B:I273	5.29	No	No	0	5	6
509	B:B:D247	B:B:S245	7.36	Yes	No	4	9	9
510	B:B:A248	B:B:I269	3.25	No	No	0	5	4
511	B:B:R251	B:B:T249	7.76	Yes	No	0	8	6
512	B:B:S265	B:B:T249	6.4	No	No	0	2	6
513	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
514	B:B:C250	B:B:I273	6.55	No	No	0	8	6
515	B:B:E260	B:B:R251	13.96	No	Yes	0	6	8
516	B:B:R251	B:B:T263	3.88	Yes	No	0	8	1
517	B:B:L252	B:B:L261	5.54	No	No	0	7	5
518	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
519	B:B:E260	B:B:F253	10.49	No	Yes	0	6	6
520	B:B:D254	B:B:R256	4.76	Yes	Yes	0	9	9
521	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
522	B:B:D254	B:B:L261	6.79	Yes	No	0	9	5
523	B:B:D254	G:G:A33	3.09	Yes	No	0	9	7
524	B:B:R256	G:G:I28	5.01	Yes	No	0	9	4
525	B:B:R256	G:G:D36	7.15	Yes	No	0	9	5
526	B:B:D258	G:G:E22	3.9	Yes	No	4	7	9
527	B:B:D258	G:G:R27	8.34	Yes	Yes	0	7	8
528	B:B:Q259	G:G:V30	5.73	Yes	No	0	6	8
529	B:B:M262	B:B:Y264	8.38	Yes	Yes	0	4	5
530	B:B:A302	B:B:M262	3.22	No	Yes	0	2	4
531	B:B:S265	B:B:T263	3.2	No	No	0	2	1
532	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
533	B:B:W297	B:B:Y264	8.68	Yes	Yes	0	8	5
534	B:B:H266	B:B:N268	5.1	No	No	0	4	4
535	B:B:H266	B:B:I269	6.63	No	No	0	4	4
536	B:B:H266	B:B:R304	6.77	No	No	0	4	5
537	B:B:I269	B:B:Y289	6.04	No	Yes	0	4	7
538	B:B:C271	B:B:Y289	4.03	Yes	Yes	1	5	7
539	B:B:C271	B:B:D290	4.67	Yes	Yes	1	5	6
540	B:B:C271	B:B:D291	7.78	Yes	No	1	5	8
541	B:B:I273	B:B:Y289	6.04	No	Yes	0	6	7
542	B:B:S275	B:B:T274	4.8	No	No	0	8	8
543	B:B:D290	B:B:T274	4.34	Yes	No	1	6	8
544	B:B:R314	B:B:T274	5.17	Yes	No	1	8	8
545	B:B:S277	B:B:V320	4.85	No	No	0	5	7
546	B:B:F278	B:B:L285	9.74	Yes	No	0	7	6
547	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
548	B:B:K280	G:G:D48	4.15	No	Yes	0	1	9
549	B:B:S281	G:G:D48	5.89	No	Yes	0	9	9
550	B:B:D298	B:B:R283	15.48	No	Yes	0	9	9
551	B:B:L300	B:B:R283	9.72	No	Yes	0	6	9
552	B:B:L284	B:B:V296	5.96	No	No	0	5	5
553	B:B:L286	B:B:V327	4.47	No	Yes	0	7	6
554	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
555	B:B:C294	B:B:G288	3.92	No	No	0	5	7
556	B:B:G288	B:B:V315	3.68	No	No	0	7	7
557	B:B:D291	B:B:Y289	3.45	No	Yes	1	8	7
558	B:B:N295	B:B:Y289	8.14	No	Yes	1	6	7
559	B:B:W297	B:B:Y289	5.79	Yes	Yes	1	8	7
560	B:B:D290	B:B:R314	7.15	Yes	Yes	1	6	8
561	B:B:N293	B:B:V307	5.91	No	No	0	5	3
562	B:B:A309	B:B:N293	4.69	No	No	0	3	5
563	B:B:C294	B:B:L308	9.52	No	No	0	5	7
564	B:B:N295	B:B:W297	4.52	No	Yes	1	6	8
565	B:B:N295	B:B:R304	18.08	No	No	1	6	5
566	B:B:R304	B:B:W297	8	No	Yes	1	5	8
567	B:B:D298	B:B:K301	9.68	No	No	0	9	5
568	B:B:L300	G:G:C41	6.35	No	No	0	6	7
569	B:B:D303	B:B:K301	4.15	No	No	0	2	5
570	B:B:L308	B:B:W339	6.83	No	Yes	0	7	9
571	B:B:A309	R:R:H409	7.32	No	Yes	0	3	7
572	B:B:G310	R:R:H409	3.18	No	Yes	0	5	7
573	B:B:H311	B:B:V315	4.15	Yes	No	0	9	7
574	B:B:H311	B:B:T329	6.85	Yes	No	0	9	8
575	B:B:H311	B:B:S331	16.74	Yes	No	23	9	9
576	B:B:D333	B:B:H311	7.56	Yes	Yes	23	9	9
577	B:B:H311	B:B:K337	9.17	Yes	No	0	9	6
578	B:B:D312	B:B:D333	6.65	No	Yes	0	5	9
579	B:B:D312	R:R:R164	4.76	No	No	0	5	7
580	B:B:D312	R:R:R405	8.34	No	No	0	5	8
581	B:B:N313	B:B:W332	4.52	No	Yes	0	7	9
582	B:B:R314	B:B:W332	32.99	Yes	Yes	1	8	9
583	B:B:C317	B:B:S316	3.44	No	No	0	7	9
584	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
585	B:B:V320	B:B:V327	4.81	No	Yes	0	7	6
586	B:B:D323	B:B:T321	5.78	No	Yes	21	7	7
587	B:B:G324	B:B:T321	3.64	No	Yes	0	9	7
588	B:B:D323	B:B:M325	6.93	No	No	0	7	5
589	B:B:M325	G:G:P49	5.03	No	No	0	5	7
590	B:B:M325	G:G:P60	5.03	No	No	0	5	9
591	B:B:A326	B:B:N340	3.13	No	Yes	20	7	9
592	B:B:A326	G:G:F61	5.55	No	Yes	20	7	8
593	B:B:V327	G:G:L50	4.47	Yes	No	0	6	9
594	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
595	B:B:D333	B:B:S331	8.83	Yes	No	23	9	9
596	B:B:D333	B:B:F335	14.33	Yes	No	0	9	4
597	B:B:F335	B:B:S334	3.96	No	No	0	4	4
598	B:B:K337	B:B:W339	9.28	No	Yes	0	6	9
599	B:B:I338	G:G:F61	6.28	No	Yes	0	5	8
600	B:B:N340	G:G:N59	8.17	Yes	No	0	9	9
601	B:B:N340	G:G:F61	3.62	Yes	Yes	20	9	8
602	G:G:S8	G:G:T6	4.8	No	No	0	4	3
603	G:G:I9	G:G:T6	6.08	No	No	0	2	3
604	G:G:L15	G:G:L19	4.15	No	No	0	2	9
605	G:G:K20	G:G:V16	6.07	No	No	0	6	7
606	G:G:M21	G:G:N24	5.61	No	No	0	1	1
607	G:G:I25	G:G:R27	10.02	No	Yes	0	2	8
608	G:G:I28	G:G:K32	4.36	No	No	0	4	5
609	G:G:H44	G:G:Y40	10.89	No	Yes	0	6	6
610	G:G:E47	G:G:K46	4.05	No	No	0	3	1
611	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
612	G:G:D48	G:G:L50	5.43	Yes	No	0	9	9
613	G:G:P55	G:G:V54	3.53	No	No	24	5	6
614	G:G:E58	G:G:V54	5.7	No	No	24	5	6
615	G:G:N59	G:G:V54	4.43	No	No	0	9	6
616	G:G:E58	G:G:P55	11	No	No	24	5	5
617	G:G:E58	G:G:S57	8.62	No	No	0	5	6
618	G:G:N59	G:G:P60	6.52	No	No	0	9	9
619	R:R:D129	R:R:L132	4.07	No	No	0	1	3
620	R:R:D129	R:R:I133	4.2	No	No	0	1	4
621	R:R:Q130	R:R:R131	7.01	No	Yes	25	3	3
622	R:R:Q130	R:R:Q364	7.68	No	No	25	3	5
623	R:R:E363	R:R:R131	4.65	No	Yes	0	5	3
624	R:R:Q364	R:R:R131	5.84	No	Yes	25	5	3
625	R:R:L137	R:R:Q138	3.99	No	No	0	6	5
626	R:R:L137	R:R:L374	4.15	No	No	0	6	6
627	R:R:I378	R:R:L137	4.28	No	No	0	8	6
628	R:R:Y141	R:R:Y145	17.87	Yes	Yes	26	7	7
629	R:R:P359	R:R:Y141	4.17	No	Yes	0	5	7
630	R:R:I378	R:R:Y141	3.63	No	Yes	0	8	7
631	R:R:S381	R:R:Y141	3.82	No	Yes	26	5	7
632	R:R:S146	R:R:V143	4.85	No	No	0	7	5
633	R:R:I187	R:R:Y145	4.84	No	Yes	0	7	7
634	R:R:L188	R:R:Y145	3.52	No	Yes	0	7	7
635	R:R:S381	R:R:Y145	10.17	No	Yes	26	5	7
636	R:R:A184	R:R:L149	4.73	No	No	0	8	6
637	R:R:F386	R:R:T151	5.19	No	No	0	5	7
638	R:R:S389	R:R:T151	6.4	No	No	0	8	7
639	R:R:F177	R:R:L152	3.65	Yes	No	0	9	9
640	R:R:F180	R:R:L152	4.87	Yes	No	0	8	9
641	R:R:L152	R:R:M181	5.65	No	No	0	9	7
642	R:R:L153	R:R:M181	4.24	No	No	0	3	7
643	R:R:I158	R:R:L154	4.28	No	No	27	8	5
644	R:R:F394	R:R:L154	6.09	Yes	No	27	8	5
645	R:R:A155	R:R:F177	4.16	No	Yes	0	9	9
646	R:R:F177	R:R:L156	4.87	Yes	No	0	9	6
647	R:R:F394	R:R:I158	3.77	Yes	No	27	8	8
648	R:R:L159	R:R:N170	4.12	No	No	0	8	9
649	R:R:I174	R:R:L159	4.28	No	No	0	7	8
650	R:R:C393	R:R:L159	4.76	No	No	0	9	8
651	R:R:E402	R:R:F162	9.33	Yes	No	0	8	7
652	R:R:L165	R:R:R164	6.07	No	No	0	9	7
653	R:R:E402	R:R:R164	15.12	Yes	No	0	8	7
654	R:R:L165	R:R:N170	5.49	No	No	0	9	9
655	R:R:E398	R:R:L165	3.98	Yes	No	0	9	9
656	R:R:H166	R:R:Y171	10.89	No	No	0	7	6
657	R:R:C167	R:R:R169	5.57	No	Yes	0	8	9
658	R:R:C167	R:R:N170	4.72	No	No	0	8	9
659	R:R:I172	R:R:T168	3.04	Yes	Yes	5	9	8
660	R:R:T168	R:R:Y240	11.24	Yes	Yes	5	8	8
661	R:R:E253	R:R:T168	7.06	No	Yes	0	5	8
662	R:R:F256	R:R:T168	5.19	No	Yes	0	5	8
663	R:R:H173	R:R:R169	5.64	No	Yes	5	9	9
664	R:R:N396	R:R:R169	6.03	No	Yes	5	9	9
665	R:R:E398	R:R:R169	4.65	Yes	Yes	5	9	9
666	R:R:F256	R:R:Y171	6.19	No	No	0	5	6
667	R:R:I172	R:R:W233	4.7	Yes	Yes	5	9	9
668	R:R:E237	R:R:I172	5.47	No	Yes	5	9	9
669	R:R:I172	R:R:Y240	6.04	Yes	Yes	5	9	8
670	R:R:E237	R:R:H173	11.08	No	No	5	9	9
671	R:R:H173	R:R:Y392	9.8	No	Yes	5	9	8
672	R:R:N175	R:R:W233	16.95	No	Yes	5	9	9
673	R:R:N175	R:R:W264	9.04	No	Yes	5	9	9
674	R:R:F180	R:R:L176	6.09	Yes	No	0	8	9
675	R:R:C393	R:R:F177	5.59	No	Yes	0	9	9
676	R:R:N230	R:R:S179	8.94	No	No	0	9	9
677	R:R:F180	R:R:N230	14.5	Yes	No	0	8	9
678	R:R:F180	R:R:V388	9.18	Yes	No	0	8	9
679	R:R:C226	R:R:R183	4.18	No	Yes	0	6	8
680	R:R:R183	R:R:V227	9.15	Yes	No	0	8	6
681	R:R:N230	R:R:R183	8.44	No	Yes	0	9	8
682	R:R:R183	R:R:V355	3.92	Yes	Yes	0	8	5
683	R:R:A186	R:R:V222	3.39	No	No	0	6	5
684	R:R:A186	R:R:T223	3.36	No	No	0	6	6
685	R:R:I187	R:R:T223	6.08	No	No	0	7	6
686	R:R:L194	R:R:R190	4.86	No	Yes	14	7	6
687	R:R:Q220	R:R:R190	5.84	No	Yes	14	5	6
688	R:R:R190	R:R:W287	5	Yes	Yes	14	6	9
689	R:R:A215	R:R:L193	3.15	No	No	0	3	5
690	R:R:C216	R:R:L193	3.17	No	No	0	9	5
691	R:R:L194	R:R:P195	4.93	No	No	0	7	3
692	R:R:L194	R:R:W287	7.97	No	Yes	14	7	9
693	R:R:A212	R:R:N210	4.69	No	No	0	6	4
694	R:R:C216	R:R:C286	7.28	No	No	0	9	9
695	R:R:R217	R:R:R278	12.79	No	Yes	0	8	8
696	R:R:Q220	R:R:Q224	7.68	No	No	0	5	6
697	R:R:Q220	R:R:W287	6.57	No	Yes	14	5	9
698	R:R:I221	R:R:W274	3.52	No	Yes	8	5	8
699	R:R:I221	R:R:V275	6.14	No	No	8	5	6
700	R:R:Q224	R:R:W274	9.86	No	Yes	0	6	8
701	R:R:W264	R:R:Y225	5.79	Yes	No	0	9	8
702	R:R:P267	R:R:Y225	4.17	Yes	No	0	9	8
703	R:R:A229	R:R:P267	3.74	No	Yes	0	8	9
704	R:R:I303	R:R:Y231	8.46	No	No	0	7	8
705	R:R:V355	R:R:Y231	7.57	Yes	No	0	5	8
706	R:R:P267	R:R:T232	5.25	Yes	No	0	9	6
707	R:R:V236	R:R:W233	6.13	No	Yes	0	8	9
708	R:R:G263	R:R:W233	9.85	No	Yes	0	9	9
709	R:R:W233	R:R:W264	18.74	Yes	Yes	5	9	9
710	R:R:V236	R:R:Y259	3.79	No	Yes	0	8	8
711	R:R:L262	R:R:V236	4.47	No	No	0	6	8
712	R:R:E237	R:R:Y392	15.71	No	Yes	5	9	8
713	R:R:L244	R:R:Y240	4.69	No	Yes	0	8	8
714	R:R:Y240	R:R:Y259	6.95	Yes	Yes	0	8	8
715	R:R:I317	R:R:L241	7.14	No	No	0	9	9
716	R:R:H242	R:R:V246	12.45	Yes	No	0	8	7
717	R:R:H242	R:R:R316	9.03	Yes	No	0	8	8
718	R:R:G250	R:R:S251	3.71	No	No	0	6	7
719	R:R:E252	R:R:G250	6.55	No	No	0	7	6
720	R:R:F270	R:R:P302	11.56	No	No	0	5	9
721	R:R:I272	R:R:P273	3.39	No	No	0	2	4
722	R:R:V275	R:R:W274	3.68	No	Yes	8	6	8
723	R:R:R278	R:R:W274	5	Yes	Yes	0	8	8
724	R:R:I295	R:R:W274	5.87	Yes	Yes	8	3	8
725	R:R:I298	R:R:W274	3.52	No	Yes	0	8	8
726	R:R:I299	R:R:W274	11.74	No	Yes	0	7	8
727	R:R:E282	R:R:R278	11.63	Yes	Yes	0	5	8
728	R:R:R278	R:R:T284	7.76	Yes	No	0	8	4
729	R:R:R278	R:R:R289	4.26	Yes	No	0	8	4
730	R:R:N283	R:R:Y279	4.65	No	No	0	6	3
731	R:R:L280	R:R:Y281	12.89	No	No	0	3	3
732	R:R:E282	R:R:E291	6.34	Yes	No	8	5	4
733	R:R:E282	R:R:V292	8.56	Yes	No	8	5	6
734	R:R:E282	R:R:I295	9.56	Yes	Yes	8	5	3
735	R:R:E288	R:R:T284	4.23	No	No	8	6	4
736	R:R:E291	R:R:T284	5.64	No	No	8	4	4
737	R:R:C286	R:R:Q285	4.58	No	No	0	9	3
738	R:R:C286	R:R:W287	7.84	No	Yes	0	9	9
739	R:R:E288	R:R:E291	6.34	No	No	8	6	4
740	R:R:R289	R:R:W296	5	No	No	0	4	6
741	R:R:I299	R:R:R289	3.76	No	No	0	7	4
742	R:R:I295	R:R:V292	6.14	Yes	No	8	3	6
743	R:R:K293	R:R:W297	8.12	No	No	0	5	7
744	R:R:W296	R:R:W297	14.99	No	No	0	6	7
745	R:R:R300	R:R:W296	13.99	Yes	No	0	7	6
746	R:R:L304	R:R:R300	3.64	No	Yes	0	4	7
747	R:R:R300	R:R:V355	6.54	Yes	Yes	0	7	5
748	R:R:P302	R:R:T301	3.5	No	No	0	9	4
749	R:R:I307	R:R:V352	6.14	No	No	0	7	6
750	R:R:L349	R:R:N310	6.87	No	No	0	9	9
751	R:R:F311	R:R:I315	7.54	No	No	0	6	5
752	R:R:F314	R:R:L318	8.53	No	No	0	9	7
753	R:R:F314	R:R:F345	4.29	No	Yes	0	9	8
754	R:R:F314	R:R:L346	9.74	No	No	0	9	9
755	R:R:L321	R:R:L325	6.92	No	No	0	9	7
756	R:R:L322	R:R:R338	7.29	No	No	0	5	9
757	R:R:R326	R:R:Y335	9.26	No	No	0	7	5
758	R:R:M330	R:R:R328	4.96	No	No	0	5	6
759	R:R:D334	R:R:M330	13.86	No	No	0	6	5
760	R:R:R331	R:R:R333	5.33	No	No	0	5	6
761	R:R:D334	R:R:R331	3.57	No	No	0	6	5
762	R:R:R333	R:R:R336	3.2	No	No	0	6	6
763	R:R:L337	R:R:R341	3.64	No	Yes	0	7	9
764	R:R:A340	R:R:R341	4.15	No	Yes	0	8	9
765	R:R:L344	R:R:R341	3.64	No	Yes	0	8	9
766	R:R:S342	R:R:T343	3.2	No	No	0	9	9
767	R:R:F345	R:R:L391	4.87	Yes	No	5	8	7
768	R:R:F345	R:R:Y392	7.22	Yes	Yes	5	8	8
769	R:R:L346	R:R:L349	4.15	No	No	0	9	9
770	R:R:P348	R:R:V347	3.53	No	No	0	9	8
771	R:R:L387	R:R:V347	4.47	No	No	0	6	8
772	R:R:P348	R:R:Q384	4.74	No	No	0	9	9
773	R:R:G351	R:R:Q384	4.93	No	No	0	9	9
774	R:R:E354	R:R:V355	5.7	No	Yes	0	7	5
775	R:R:E354	R:R:L380	7.95	No	No	0	7	7
776	R:R:E354	R:R:S381	7.19	No	No	0	7	5
777	R:R:F357	R:R:K373	6.2	No	No	28	7	7
778	R:R:E377	R:R:F357	7	No	No	28	7	7
779	R:R:L374	R:R:T361	4.42	No	No	0	6	7
780	R:R:L369	R:R:R370	12.15	No	No	0	4	5
781	R:R:E377	R:R:K373	5.4	No	No	28	7	7
782	R:R:G375	R:R:I378	3.53	No	No	0	5	8
783	R:R:F376	R:R:L380	4.87	No	No	0	4	7
784	R:R:F379	R:R:L380	7.31	No	No	0	6	7
785	R:R:F379	R:R:F383	17.15	No	Yes	0	6	6
786	R:R:F383	R:R:S382	7.93	Yes	No	0	6	9
787	R:R:F383	R:R:F386	16.08	Yes	No	0	6	5
788	R:R:F383	R:R:L387	6.09	Yes	No	0	6	6
789	R:R:V388	R:R:Y392	3.79	No	Yes	0	9	8
790	R:R:F394	R:R:V390	5.24	Yes	No	0	8	5
791	R:R:L391	R:R:Y392	9.38	No	Yes	5	7	8
792	R:R:C393	R:R:F394	5.59	No	Yes	0	9	8
793	R:R:E398	R:R:N396	10.52	Yes	No	5	9	9
794	R:R:N396	R:R:V399	4.43	No	No	0	9	9
795	R:R:K397	R:R:Q400	6.78	No	No	0	5	8
796	R:R:E402	R:R:R405	10.47	Yes	No	0	8	8
797	R:R:H409	R:R:R405	12.41	Yes	No	0	7	8
798	R:R:H408	R:R:W407	5.29	No	No	0	4	5
799	R:R:R411	R:R:W407	8	No	No	0	4	5
800	R:R:C410	R:R:R414	11.14	No	No	0	4	5
801	R:R:R411	R:R:R414	9.6	No	No	0	4	5
802	G:G:A12	G:G:Q11	3.03	No	No	0	5	3
803	A:A:A316	A:A:E309	3.02	No	No	0	2	4
804	G:G:A43	G:G:E42	3.02	No	No	0	4	1
805	A:A:F208	A:A:G225	3.01	No	No	0	6	9
806	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
807	B:B:G306	B:B:R42	3	No	No	0	4	2
808	B:B:L318	B:B:S275	3	No	No	0	6	8
809	B:B:L318	B:B:S277	3	No	No	0	6	5
810	B:B:L284	B:B:S279	3	No	No	0	5	9
811	R:R:L247	R:R:S243	3	No	No	0	5	7
812	R:R:L318	R:R:S342	3	No	No	0	7	9
813	R:R:L339	R:R:S342	3	No	No	0	9	9
814	R:R:G367	R:R:R370	3	No	No	0	4	5
815	A:A:L297	A:A:V301	2.98	No	No	0	9	7
816	B:B:L285	B:B:V276	2.98	No	No	0	6	6
817	R:R:L235	R:R:V239	2.98	Yes	No	0	8	7
818	A:A:N292	A:A:V247	2.96	No	Yes	0	9	7
819	A:A:L282	A:A:T285	2.95	No	No	0	9	7
820	B:B:L152	B:B:T196	2.95	No	No	0	3	1
821	R:R:L235	R:R:T306	2.95	Yes	No	0	8	7
822	A:A:I235	A:A:I276	2.94	No	No	0	9	8
823	A:A:I308	A:A:I341	2.94	Yes	No	0	7	7
824	B:B:D246	B:B:S227	2.94	No	No	0	9	6
825	G:G:A43	G:G:H44	2.93	No	No	0	4	6
826	A:A:N218	A:A:T40	2.92	No	No	0	4	6
827	B:B:I37	G:G:M38	2.92	No	No	0	2	4
828	B:B:G64	B:B:Y105	2.9	No	No	0	5	6
829	B:B:D322	B:B:T65	2.89	No	No	0	1	1
830	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
831	B:B:D170	B:B:T177	2.89	No	No	0	9	4
832	B:B:M217	G:G:M21	2.89	No	No	0	3	1
833	A:A:I235	A:A:L282	2.85	No	No	0	9	9
834	A:A:I276	A:A:L272	2.85	No	No	0	8	9
835	A:A:E330	A:A:V334	2.85	No	No	0	3	4
836	B:B:E10	G:G:V16	2.85	No	No	0	8	7
837	R:R:I133	R:R:L134	2.85	No	No	0	4	5
838	R:R:I309	R:R:L235	2.85	No	Yes	0	6	8
839	R:R:I320	R:R:L245	2.85	No	No	0	8	8
840	R:R:I307	R:R:L349	2.85	No	No	0	7	9
841	R:R:L149	R:R:M181	2.83	No	No	0	6	7
842	R:R:L325	R:R:M330	2.83	No	No	0	7	5
843	A:A:L30	B:B:K89	2.82	No	Yes	0	6	9
844	A:A:K34	B:B:L55	2.82	No	No	0	5	6
845	B:B:K15	G:G:L19	2.82	No	No	0	6	9
846	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
847	A:A:K293	A:A:N292	2.8	Yes	No	0	9	9
848	A:A:P326	A:A:Y339	2.78	No	Yes	0	1	3
849	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
850	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
851	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
852	R:R:L176	R:R:L234	2.77	No	No	0	9	9
853	R:R:A219	R:R:R190	2.77	No	Yes	0	6	6
854	R:R:A266	R:R:F270	2.77	No	No	0	4	5
855	R:R:A368	R:R:F371	2.77	No	No	0	1	4
856	R:R:L235	R:R:N310	2.75	Yes	No	0	8	9
857	B:B:H183	B:B:T164	2.74	Yes	No	0	9	6
858	A:A:E392	R:R:I395	2.73	No	No	0	6	5
859	G:G:E17	G:G:M21	2.71	No	No	0	6	1
860	B:B:E12	B:B:K15	2.7	Yes	No	0	4	6
861	R:R:A268	R:R:Y225	2.67	No	No	0	3	8
862	R:R:H242	R:R:I313	2.65	Yes	No	0	8	8
863	R:R:H242	R:R:I317	2.65	Yes	No	0	8	9
864	B:B:E130	B:B:N132	2.63	No	No	0	3	3
865	R:R:E288	R:R:N290	2.63	No	No	0	6	6
866	R:R:R300	R:R:V356	2.62	Yes	No	0	7	6
867	A:A:D11	A:A:E15	2.6	No	No	0	1	5
868	A:A:R385	R:R:T327	2.59	Yes	No	0	6	6
869	B:B:R49	B:B:T87	2.59	No	No	0	7	5
870	B:B:E10	B:B:Q6	2.55	No	No	0	8	1
871	R:R:S148	R:R:Y145	2.54	No	Yes	0	9	7
872	R:R:S243	R:R:Y259	2.54	No	Yes	0	7	8
873	G:G:I9	G:G:R13	2.51	No	No	0	2	6
874	A:A:K17	A:A:R20	2.48	No	No	0	4	3
875	A:A:K307	A:A:R265	2.48	Yes	No	0	5	9
876	A:A:M386	A:A:R356	2.48	No	No	0	3	2
877	R:R:M140	R:R:R136	2.48	No	No	0	6	4
878	R:R:K373	R:R:R370	2.48	No	No	0	7	5
879	R:R:V271	R:R:W274	2.45	No	Yes	0	6	8
880	R:R:V360	R:R:W287	2.45	No	Yes	0	4	9
881	R:R:F386	R:R:L147	2.44	No	No	0	5	5
882	R:R:F162	R:R:L161	2.44	No	No	0	7	3
883	B:B:L139	B:B:R137	2.43	No	No	0	9	5
884	B:B:R283	G:G:L51	2.43	Yes	No	0	9	6
885	R:R:L128	R:R:R131	2.43	No	Yes	0	3	3
886	R:R:L134	R:R:R131	2.43	No	Yes	0	5	3
887	R:R:T178	R:R:W264	2.43	No	Yes	0	3	9
888	R:R:T301	R:R:W297	2.43	No	No	0	4	7
889	R:R:L322	R:R:R326	2.43	No	No	0	5	7
890	R:R:Q329	R:R:R326	2.34	No	No	0	7	7
891	R:R:L260	R:R:W264	2.28	No	Yes	0	6	9
892	R:R:H255	R:R:Y259	2.18	No	Yes	0	4	8
893	R:R:F345	R:R:R341	2.14	Yes	Yes	0	8	9
894	R:R:G249	R:R:G250	2.11	No	No	0	7	6
895	A:A:R38	A:A:Y37	2.06	No	Yes	0	3	3
896	A:A:G329	A:A:P328	2.03	No	No	0	8	2
897	R:R:G228	R:R:P267	2.03	No	Yes	0	5	9
898	R:R:G265	R:R:P267	2.03	No	Yes	0	6	9
899	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
900	B:B:C271	B:B:G272	1.96	Yes	No	0	5	4
901	B:B:C317	B:B:G330	1.96	No	No	0	7	5
902	A:A:A226	A:A:G206	1.95	No	No	0	9	8
903	B:B:A140	B:B:G141	1.95	No	No	0	5	5
904	B:B:A193	B:B:P194	1.87	No	No	0	4	4
905	R:R:A358	R:R:P359	1.87	No	No	0	6	5
906	B:B:G202	B:B:S189	1.86	No	No	0	6	7
907	R:R:G144	R:R:S382	1.86	No	No	0	8	9
908	R:R:G385	R:R:S148	1.86	No	No	0	9	9
909	A:A:V217	R:R:G249	1.84	No	No	0	6	7
910	B:B:G41	B:B:V40	1.84	No	No	0	1	3
911	B:B:G306	B:B:V296	1.84	No	No	0	4	5
912	R:R:G144	R:R:V143	1.84	No	No	0	8	5
913	A:A:G52	A:A:T55	1.82	No	No	0	9	9
914	B:B:G174	B:B:T173	1.82	No	No	0	4	5
915	B:B:G182	B:B:T181	1.82	No	No	0	6	2
916	A:A:A269	A:A:A48	1.79	No	No	0	9	8
917	R:R:G238	R:R:I313	1.76	No	No	0	9	8
918	A:A:P326	A:A:T325	1.75	No	No	0	1	1
919	G:G:P53	G:G:T52	1.75	No	No	0	8	4
920	A:A:G304	A:A:K305	1.74	No	No	0	5	3
921	A:A:A249	A:A:S51	1.71	No	No	0	8	9
922	B:B:A28	G:G:S31	1.71	No	No	0	4	9
923	R:R:A219	R:R:S189	1.71	No	No	0	6	5
924	A:A:G52	A:A:N292	1.7	No	No	0	9	9
925	R:R:A294	R:R:V292	1.7	No	No	0	3	6
926	B:B:E130	B:B:G131	1.64	No	No	0	3	4
927	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
928	B:B:I33	G:G:A34	1.62	No	No	0	3	6
929	B:B:A11	B:B:K15	1.61	No	No	0	5	6
930	B:B:S207	B:B:T223	1.6	No	No	0	5	2
931	R:R:S323	R:R:T327	1.6	No	No	0	7	6
932	A:A:T40	A:A:V36	1.59	No	No	0	6	2
933	A:A:T210	A:A:V57	1.59	No	No	0	7	8
934	R:R:T142	R:R:V139	1.59	No	No	0	7	3
935	R:R:C226	R:R:L182	1.59	No	No	0	6	7
936	R:R:T218	R:R:V222	1.59	No	No	0	3	5
937	R:R:G406	R:R:H409	1.59	No	Yes	0	5	7
938	B:B:L4	G:G:A12	1.58	Yes	No	0	4	5
939	B:B:L30	G:G:A34	1.58	No	No	0	5	6
940	B:B:A240	G:G:L37	1.58	No	No	0	6	7
941	R:R:I174	R:R:S160	1.55	No	No	0	7	3
942	R:R:I276	R:R:V277	1.54	No	No	0	3	5
943	R:R:I295	R:R:V277	1.54	Yes	No	0	3	5
944	B:B:Q17	G:G:A23	1.52	No	No	0	4	8
945	R:R:M140	R:R:V143	1.52	No	No	0	6	5
946	A:A:M221	A:A:T210	1.51	Yes	No	0	8	7
947	A:A:A298	A:A:E299	1.51	No	No	0	5	5
948	G:G:A39	G:G:E42	1.51	No	No	0	3	1
949	R:R:M305	R:R:T301	1.51	No	No	0	4	4
950	A:A:G49	A:A:R265	1.5	No	No	0	8	9
951	B:B:V307	R:R:L412	1.49	No	No	0	3	4
952	R:R:L350	R:R:V347	1.49	No	No	0	9	8
953	G:G:L51	G:G:T52	1.47	No	No	0	6	4
954	R:R:I272	R:R:I276	1.47	No	No	0	2	3
955	A:A:N264	A:A:T263	1.46	No	No	0	9	7
956	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
957	R:R:E398	R:R:S401	1.44	Yes	No	0	9	4
958	R:R:E402	R:R:S401	1.44	Yes	No	0	8	4
959	R:R:I395	R:R:L391	1.43	No	No	0	5	7
960	R:R:Q400	R:R:V399	1.43	No	No	0	8	9
961	A:A:E330	A:A:T335	1.41	No	No	0	3	4
962	B:B:A299	B:B:F278	1.39	No	Yes	0	5	7
963	R:R:C410	R:R:R413	1.39	No	No	0	4	4
964	B:B:A21	G:G:R27	1.38	No	Yes	0	4	8
965	G:G:A56	G:G:R62	1.38	No	No	0	4	7
966	R:R:L213	R:R:N210	1.37	No	No	0	4	4
967	R:R:I403	R:R:Q400	1.37	No	No	0	5	8
968	A:A:K34	A:A:Q31	1.36	No	No	0	5	4
969	A:A:D11	A:A:N14	1.35	No	No	0	1	3
970	B:B:K280	G:G:E47	1.35	No	No	0	1	3
971	B:B:D153	B:B:D154	1.33	No	No	0	5	6
972	R:R:N210	R:R:Q211	1.32	No	No	0	4	3
973	R:R:R411	R:R:S415	1.32	No	No	0	4	5
974	A:A:E10	A:A:N14	1.31	No	No	0	2	3
975	A:A:Q31	A:A:Q35	1.28	No	No	0	4	4
976	R:R:T142	R:R:Y141	1.25	No	Yes	0	7	7
977	R:R:I403	R:R:R404	1.25	No	No	0	5	6
978	G:G:K14	G:G:R13	1.24	No	No	0	4	6
979	R:R:F311	R:R:L312	1.22	No	No	0	6	4
980	R:R:F311	R:R:L346	1.22	No	No	0	6	9
981	B:B:F292	B:B:N313	1.21	No	No	0	4	7
982	R:R:L318	R:R:R338	1.21	No	No	0	7	9
983	R:R:L339	R:R:R338	1.21	No	No	0	9	9
984	A:A:D323	A:A:R342	1.19	No	Yes	0	3	5
985	B:B:D5	B:B:R8	1.19	No	No	0	1	3
986	B:B:D20	B:B:R19	1.19	No	No	0	2	4
987	A:A:E314	A:A:R317	1.16	Yes	No	0	5	2
988	R:R:E282	R:R:Y281	1.12	Yes	No	0	5	3
989	R:R:H255	R:R:Y258	1.09	No	No	0	4	3
990	R:R:R404	R:R:W407	1	No	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Y37	8.0225	4	2	3
2	A:A:K53	5.475	4	16	9
3	A:A:F219	7.128	5	15	8
4	A:A:H220	8.9925	4	1	7
5	A:A:M221	3.815	4	0	8
6	A:A:F222	9.28	5	1	6
7	A:A:Q227	5.175	4	1	9
8	A:A:E230	6.02	4	1	9
9	A:A:K233	6.77	5	1	9
10	A:A:W234	7.52	4	1	9
11	A:A:F246	4.352	5	10	9
12	A:A:V247	4.105	4	0	7
13	A:A:Q267	5.22	4	0	4
14	A:A:F273	5.14333	6	10	9
15	A:A:W277	11.2525	4	10	6
16	A:A:W281	13.0925	4	1	5
17	A:A:L289	4.445	4	10	9
18	A:A:F290	6.48	5	18	9
19	A:A:K293	4.5625	4	17	9
20	A:A:Q294	6.92	4	3	6
21	A:A:K307	6.3175	4	0	5
22	A:A:I308	4.442	5	3	7
23	A:A:F312	5.356	5	3	8
24	A:A:E314	4.694	5	3	5
25	A:A:F315	10.34	5	3	6
26	A:A:Y318	7.006	5	3	7
27	A:A:P321	4.8075	4	3	4
28	A:A:Y339	6.1275	4	3	3
29	A:A:F340	9.19167	6	3	6
30	A:A:R342	5.61	6	3	5
31	A:A:F345	7.8	4	10	8
32	A:A:Y360	10.436	5	9	8
33	A:A:F363	7.806	5	3	5
34	A:A:R373	4.78	4	11	6
35	A:A:R374	7.545	4	0	4
36	A:A:F376	4.4825	4	11	9
37	A:A:R385	5.618	5	9	6
38	A:A:H387	7.1	4	19	8
39	B:B:L4	5.5225	4	0	4
40	B:B:E12	8.0325	4	0	4
41	B:B:H54	9.12167	6	2	9
42	B:B:K57	9.84	5	1	9
43	B:B:Y59	10.486	5	1	8
44	B:B:W63	6.562	5	0	7
45	B:B:D76	6.642	5	2	9
46	B:B:K78	4.744	5	2	8
47	B:B:L79	3.74	4	13	7
48	B:B:W82	9.84143	7	2	9
49	B:B:D83	9.215	4	2	8
50	B:B:K89	6.89833	6	2	9
51	B:B:L95	4.958	5	13	8
52	B:B:W99	9.728	5	1	9
53	B:B:M101	4.78	4	1	9
54	B:B:Y111	7.685	4	22	4
55	B:B:C114	4.215	4	13	8
56	B:B:E138	4.97	4	0	6
57	B:B:H142	8.295	4	6	9
58	B:B:Y145	6.58714	7	1	8
59	B:B:F151	4.382	5	0	9
60	B:B:I157	3.6875	4	6	7
61	B:B:T159	4.962	5	6	9
62	B:B:D163	7.02	4	6	9
63	B:B:W169	8.92833	6	6	8
64	B:B:Q176	7.538	5	6	4
65	B:B:F180	7.14	5	7	7
66	B:B:H183	8.08167	6	7	9
67	B:B:D186	5.5525	4	1	9
68	B:B:M188	6.635	4	1	8
69	B:B:F199	7.002	5	7	9
70	B:B:C204	4.93667	6	1	7
71	B:B:D205	8.1075	4	7	9
72	B:B:K209	11.5725	4	7	6
73	B:B:W211	10.166	5	7	8
74	B:B:Q220	6.21667	6	4	7
75	B:B:F222	7.5375	4	4	8
76	B:B:H225	8.48	6	4	9
77	B:B:I232	5.0975	4	4	8
78	B:B:F235	7.65	6	12	6
79	B:B:P236	5.6675	4	12	7
80	B:B:F241	6.726	5	4	6
81	B:B:T243	5.8425	4	4	8
82	B:B:D247	8.135	4	4	9
83	B:B:R251	10.35	4	0	8
84	B:B:F253	10.2525	4	4	6
85	B:B:D254	4.8175	4	0	9
86	B:B:R256	6.64	4	0	9
87	B:B:D258	7.092	5	4	7
88	B:B:Q259	4.2075	4	0	6
89	B:B:M262	5.435	4	0	4
90	B:B:Y264	6.328	5	0	5
91	B:B:C271	4.61	4	1	5
92	B:B:F278	5.576	5	12	7
93	B:B:R283	7.8475	4	0	9
94	B:B:Y289	5.54714	7	1	7
95	B:B:D290	5.995	4	1	6
96	B:B:W297	6.7475	4	1	8
97	B:B:H311	8.894	5	23	9
98	B:B:R314	13.194	5	1	8
99	B:B:T321	6.685	4	21	7
100	B:B:V327	4.1975	4	0	6
101	B:B:W332	11.01	6	1	9
102	B:B:D333	9.3425	4	23	9
103	B:B:W339	7.3625	4	0	9
104	B:B:N340	4.635	4	20	9
105	G:G:R27	5.98	4	0	8
106	G:G:Y40	8.8025	4	12	6
107	G:G:D48	5.504	5	0	9
108	G:G:F61	5.59	5	20	8
109	R:R:R131	4.472	5	25	3
110	R:R:Y141	6.148	5	26	7
111	R:R:Y145	7.788	5	26	7
112	R:R:T168	6.6325	4	5	8
113	R:R:R169	6.642	5	5	9
114	R:R:I172	4.8125	4	5	9
115	R:R:F177	4.5675	4	0	9
116	R:R:F180	8.66	4	0	8
117	R:R:R183	6.4225	4	0	8
118	R:R:R190	4.6175	4	14	6
119	R:R:W233	11.274	5	5	9
120	R:R:L235	2.8825	4	0	8
121	R:R:Y240	7.23	4	5	8
122	R:R:H242	6.695	4	0	8
123	R:R:Y259	3.865	4	0	8
124	R:R:W264	7.656	5	5	9
125	R:R:P267	3.444	5	0	9
126	R:R:W274	5.705	8	8	8
127	R:R:R278	8.288	5	0	8
128	R:R:E282	7.442	5	8	5
129	R:R:W287	5.966	5	14	9
130	R:R:I295	5.7775	4	8	3
131	R:R:R300	6.6975	4	0	7
132	R:R:R341	3.3925	4	0	9
133	R:R:F345	4.434	5	5	8
134	R:R:V355	5.9325	4	0	5
135	R:R:F383	11.8125	4	0	6
136	R:R:Y392	9.18	5	5	8
137	R:R:F394	5.1725	4	27	8
138	R:R:E398	5.1475	4	5	9
139	R:R:E402	9.09	4	0	8
140	R:R:H409	6.125	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:H41	A:A:I383	10.2867	5.3	No	No	0	6	8
2	A:A:H387	A:A:I383	18.3824	5.3	Yes	No	0	8	8
3	A:A:H387	R:R:L244	19.9465	14.14	Yes	No	0	8	8
4	R:R:L244	R:R:Y240	20.1691	4.69	No	Yes	0	8	8
5	R:R:I172	R:R:Y240	21.4231	6.04	Yes	Yes	5	9	8
6	R:R:E237	R:R:I172	26.0976	5.47	No	Yes	5	9	9
7	R:R:E237	R:R:H173	24.0153	11.08	No	No	5	9	9
8	R:R:H173	R:R:R169	60.1815	5.64	No	Yes	5	9	9
9	R:R:E398	R:R:R169	61.1764	4.65	Yes	Yes	5	9	9
10	R:R:E398	R:R:L165	63.6325	3.98	Yes	No	0	9	9
11	R:R:L165	R:R:R164	95.2027	6.07	No	No	0	9	7
12	B:B:D312	R:R:R164	96.1481	4.76	No	No	0	5	7
13	B:B:D312	B:B:D333	98.7267	6.65	No	Yes	0	5	9
14	B:B:D333	B:B:H311	98.971	7.56	Yes	Yes	23	9	9
15	B:B:H311	B:B:T329	49.5574	6.85	Yes	No	0	9	8
16	B:B:T329	B:B:W339	49.6054	9.7	No	Yes	0	8	9
17	B:B:L308	B:B:W339	99.7044	6.83	No	Yes	0	7	9
18	B:B:L308	B:B:M45	100	9.9	No	No	0	7	4
19	B:B:M45	B:B:V327	99.9939	3.04	No	Yes	0	4	6
20	B:B:V327	G:G:L50	11.9207	4.47	Yes	No	0	6	9
21	G:G:D48	G:G:L50	11.736	5.43	Yes	No	0	9	9
22	B:B:H311	B:B:K337	49.6104	9.17	Yes	No	0	9	6
23	B:B:K337	B:B:W339	50.1103	9.28	No	Yes	0	6	9
24	A:A:F246	A:A:L272	55.6411	6.09	Yes	No	0	9	9
25	A:A:L272	A:A:R231	55.8909	8.5	No	No	0	9	9
26	A:A:R231	A:A:W234	56.0198	9	No	Yes	0	9	9
27	A:A:W234	B:B:Y145	52.5801	5.79	Yes	Yes	1	9	8
28	B:B:M101	B:B:Y145	87.7306	7.18	Yes	Yes	1	9	8
29	B:B:M101	B:B:Y59	87.7673	3.59	Yes	Yes	1	9	8
30	B:B:W332	B:B:Y59	87.8338	8.68	Yes	Yes	1	9	8
31	A:A:Q227	B:B:N119	18.36	5.28	Yes	No	0	9	9
32	A:A:Q227	B:B:Y145	14.9976	5.64	Yes	Yes	1	9	8
33	A:A:K233	B:B:Y145	31.5246	3.58	Yes	Yes	1	9	8
34	A:A:K233	B:B:N230	31.6849	5.6	Yes	No	0	9	9
35	B:B:R314	B:B:W332	88.0549	32.99	Yes	Yes	1	8	9
36	A:A:F246	A:A:V248	18.0194	3.93	Yes	No	0	9	7
37	A:A:F246	A:A:F273	19.1857	3.22	Yes	Yes	10	9	9
38	A:A:F246	A:A:L289	18.183	3.65	Yes	Yes	10	9	9
39	A:A:F345	A:A:V248	17.5528	7.87	Yes	No	0	8	7
40	A:A:F273	A:A:F345	17.6305	7.5	Yes	Yes	10	9	8
41	A:A:F345	A:A:L289	17.5609	6.09	Yes	Yes	10	8	9
42	A:A:F345	A:A:L270	52.2444	9.74	Yes	No	0	8	6
43	A:A:L270	A:A:Q267	51.7531	3.99	No	Yes	0	6	4
44	A:A:F312	A:A:Q267	45.7595	3.51	Yes	Yes	0	8	4
45	A:A:F312	A:A:F340	34.8401	6.43	Yes	Yes	3	8	6
46	A:A:F340	A:A:Y318	28.3406	12.38	Yes	Yes	3	6	7
47	A:A:P321	A:A:Y318	13.6925	4.17	Yes	Yes	3	4	7
48	A:A:P321	A:A:Y339	12.6889	8.34	Yes	Yes	3	4	3
49	A:A:F363	A:A:Y339	10.6666	6.19	Yes	Yes	3	5	3
50	A:A:F363	A:A:Q294	15.2381	10.54	Yes	Yes	3	5	6
51	A:A:D343	A:A:Y318	13.1868	9.2	No	Yes	3	3	7
52	A:A:D343	A:A:R342	12.6836	5.96	No	Yes	3	3	5
53	A:A:F363	A:A:R342	10.6621	7.48	Yes	Yes	3	5	5
54	A:A:Q294	A:A:S250	12.1995	5.78	Yes	No	0	6	7
55	A:A:L297	A:A:S250	11.184	7.51	No	No	0	9	7
56	A:A:L297	A:A:V301	10.1684	2.98	No	No	0	9	7
57	R:R:H173	R:R:Y392	35.9893	9.8	No	Yes	5	9	8
58	B:B:D246	B:B:N230	31.5194	5.39	No	No	0	9	9
59	B:B:D246	B:B:S227	31.3533	2.94	No	No	0	9	6
60	B:B:S227	B:B:S245	15.5012	3.26	No	No	4	6	9
61	B:B:H225	B:B:S245	15.3256	11.16	Yes	No	4	9	9
62	B:B:H225	B:B:T243	26.991	8.21	Yes	Yes	4	9	8
63	B:B:F253	B:B:T243	19.9722	9.08	Yes	Yes	4	6	8
64	B:B:F222	B:B:F253	18.9051	9.65	Yes	Yes	4	8	6
65	B:B:D258	B:B:F222	16.4001	5.97	Yes	Yes	4	7	8
66	B:B:D258	B:B:R22	13.0819	10.72	Yes	No	0	7	6
67	B:B:I18	B:B:R22	11.6179	5.01	No	No	0	7	6
68	B:B:I18	G:G:A23	11.2464	3.25	No	No	0	7	8
69	B:B:Q17	G:G:A23	10.8746	1.52	No	No	0	4	8
70	B:B:L14	B:B:Q17	10.5026	3.99	No	No	0	8	4
71	B:B:D247	B:B:S227	15.6857	5.89	Yes	No	4	9	6
72	B:B:D247	B:B:H225	15.3345	6.3	Yes	Yes	4	9	9
73	B:B:C271	B:B:D290	14.4598	4.67	Yes	Yes	1	5	6
74	B:B:C271	B:B:Y289	13.8806	4.03	Yes	Yes	1	5	7
75	B:B:W297	B:B:Y289	11.7313	5.79	Yes	Yes	1	8	7
76	B:B:W297	B:B:Y264	11.3646	8.68	Yes	Yes	0	8	5
77	B:B:G144	B:B:N119	17.8199	3.39	No	No	0	8	9
78	B:B:D163	B:B:G144	17.4491	3.35	Yes	No	6	9	8
79	B:B:D163	B:B:S161	16.7222	8.83	Yes	No	6	9	9
80	B:B:H142	B:B:S161	16.5894	15.34	Yes	No	6	9	9
81	B:B:H142	B:B:T159	10.4381	5.48	Yes	Yes	6	9	9
82	B:B:V320	B:B:V327	90.2781	4.81	No	Yes	0	7	6
83	B:B:S277	B:B:V320	90.2531	4.85	No	No	0	5	7
84	B:B:L318	B:B:S277	90.2297	3	No	No	0	6	5
85	B:B:L318	B:B:S275	90.2116	3	No	No	0	6	8
86	B:B:R314	B:B:T274	81.6667	5.17	Yes	No	1	8	8
87	R:R:L165	R:R:N170	31.4553	5.49	No	No	0	9	9
88	R:R:L159	R:R:N170	31.1973	4.12	No	No	0	8	9
89	R:R:C393	R:R:L159	30.5662	4.76	No	No	0	9	8
90	R:R:C393	R:R:F177	29.6108	5.59	No	Yes	0	9	9
91	R:R:F177	R:R:L152	29.0726	3.65	Yes	No	0	9	9
92	R:R:F180	R:R:L152	28.2031	4.87	Yes	No	0	8	9
93	R:R:F180	R:R:N230	57.2207	14.5	Yes	No	0	8	9
94	R:R:N230	R:R:R183	56.3884	8.44	No	Yes	0	9	8
95	R:R:R183	R:R:V355	54.7211	3.92	Yes	Yes	0	8	5
96	R:R:E354	R:R:V355	18.4805	5.7	No	Yes	0	7	5
97	R:R:V388	R:R:Y392	30.9251	3.79	No	Yes	0	9	8
98	R:R:F180	R:R:V388	30.7173	9.18	Yes	No	0	8	9
99	R:R:R300	R:R:V355	35.7285	6.54	Yes	Yes	0	7	5
100	R:R:R300	R:R:W296	34.4468	13.99	Yes	No	0	7	6
101	R:R:R289	R:R:W296	31.0196	5	No	No	0	4	6
102	R:R:R278	R:R:R289	18.7922	4.26	Yes	No	0	8	4
103	R:R:R278	R:R:W274	11.3873	5	Yes	Yes	0	8	8
104	R:R:Q224	R:R:W274	14.0305	9.86	No	Yes	0	6	8
105	R:R:Q220	R:R:Q224	13.1552	7.68	No	No	0	5	6
106	R:R:I299	R:R:R289	11.8001	3.76	No	No	0	7	4
107	R:R:I299	R:R:W274	11.3665	11.74	No	Yes	0	7	8
108	B:B:S275	B:B:T274	90.1958	4.8	No	No	0	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8WA3

PDB Summary
PDB	8WA3
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GIP
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	2.86
Date	2024-03-06
D.O.I.	10.1038/s41421-024-00649-0

Net Summary
I_min	3.04
Number of Linked Nodes	857
Number of Links	990
Number of Hubs	140
Number of Links mediated by Hubs	532
Number of Communities	28
Number of Nodes involved in Communities	206
Number of Links involved in Communities	280

Path Summary
Number Of Nodes in MetaPath	109
Number Of Links MetaPath	108
Number of Shortest Paths	1339258
Length Of Smallest Path	3
Average Path Length	35.5307
Length of Longest Path	65
Minimum Path Strength	1.125
Average Path Strength	6.8527
Maximum Path Strength	24.49
Minimum Path Correlation	0.7
Average Path Correlation	0.981993
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.7027
Average % Of Corr. Nodes	41.9579
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.3616
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• response to stimulus • response to stress • response to wounding • response to axon injury • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • response to metal ion • response to chemical • response to calcium ion • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • negative adaptation of signaling pathway • negative regulation of signaling • negative regulation of biological process • desensitization of G protein-coupled receptor signaling pathway • regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • negative regulation of cellular process • regulation of G protein-coupled receptor signaling pathway • regulation of signaling • negative regulation of response to stimulus • negative regulation of signal transduction • regulation of response to stimulus • adaptation of signaling pathway • regulation of cell communication • metabolic process • generation of precursor metabolites and energy • response to hexose • response to monosaccharide • response to carbohydrate • response to glucose • response to oxygen-containing compound • gastric inhibitory peptide signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • developmental process • multicellular organism development • multicellular organismal process • pancreas development • endocrine system development • anatomical structure development • animal organ development • endocrine pancreas development • system development • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • cell surface receptor signaling pathway • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to lipid • response to fatty acid • response to nutrient levels • response to nutrient • positive regulation of cell communication • positive regulation of establishment of protein localization • positive regulation of insulin secretion • positive regulation of peptide hormone secretion • positive regulation of protein localization • positive regulation of biological process • positive regulation of secretion by cell • positive regulation of protein transport • positive regulation of hormone secretion • positive regulation of secretion • positive regulation of cellular process • positive regulation of peptide secretion • positive regulation of protein secretion • positive regulation of transport • positive regulation of signaling • cellular anatomical structure • membrane • cell periphery • plasma membrane • peptide hormone receptor binding • protein binding • binding • corticotropin-releasing hormone receptor binding • signaling receptor binding • G protein-coupled receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • mu-type opioid receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • ionotropic glutamate receptor binding • glutamate receptor binding • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • insulin-like growth factor receptor binding • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • intracellular anatomical structure • cytoplasm • cytoskeletal protein binding • spectrin binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to stress • response to hypoxia • response to oxygen levels • response to abiotic stimulus • cell population proliferation • phospholipase C-activating G protein-coupled receptor signaling pathway • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • organelle • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding • response to ketone • response to prostaglandin • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P04896
Sequence	>8WA3_Chain_A T E D Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A G E S G K N T I V K Q M S G I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V A S S Q T N R L Q A A L K L F D S I W N N K W L R D T S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C S V D T E N I R R V F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8WA3_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8WA3_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P48546
Sequence	>8WA3_Chain_R L D Q R L I L E R L Q V M Y T V G Y S L S L A T L L L A L L I L S L F R R L H C T R N Y I H I N L F T S F M L R A A A I L S R D R L L P N Q A L A A C R T A Q I V T Q Y C V G A N Y T W L L V E G V Y L H S L L V L V G G S E E G H F R Y Y L L L G W G A P A L F V I P W V I V R Y L Y E N T Q C W E R N E V K A I W W I I R T P I L M T I L I N F L I F I R I L G I L L S K L R T R Q M R C R D Y R L R L A R S T L F L V P L L G V H E V V F A P V T E E Q A R G A L R F A K L G F E I F L S S F Q G F L V S V L Y C F I N K E V Q S E I R R G W H H C R L R R S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8YW4	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ22	3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW4 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-		3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	2.86	2024-03-06	10.1038/s41421-024-00649-0
	8WA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		2.86	2024-03-06	10.1038/s41421-024-00649-0
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.13	2023-10-18	10.1073/pnas.2306145120
	8ITM (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.13	2023-10-18	10.1073/pnas.2306145120
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.23	2023-10-18	10.1073/pnas.2306145120
	8ITL (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.23	2023-10-18	10.1073/pnas.2306145120
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774	chim(NtGi1-Gs)/β1/γ2	3.08	2022-04-13	10.1073/pnas.2116506119
	7RBT (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774		3.08	2022-04-13	10.1073/pnas.2116506119
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/β1/γ2	3.24	2022-04-13	10.1073/pnas.2116506119
	7RA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		3.24	2022-04-13	10.1073/pnas.2116506119
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-03-02	10.1038/s41467-022-28683-0
	7VAB (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-		3.2	2022-03-02	10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/β1/γ2	3.1	2022-02-23	10.1038/s41467-022-28683-0
	7FIN (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-		3.1	2022-02-23	10.1038/s41467-022-28683-0
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/β1/γ2	2.98	2021-08-04	10.7554/eLife.68719
	7DTY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		2.98	2021-08-04	10.7554/eLife.68719

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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