psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I46	R:R:K48	10.18	No	No	0	5	4
2	R:R:N47	R:R:R294	7.23	No	No	0	4	2
3	R:R:I53	R:R:Y49	12.09	No	No	0	5	2
4	R:R:F50	R:R:I54	10.05	No	No	0	5	5
5	R:R:V51	R:R:Y55	7.57	No	Yes	3	5	7
6	R:R:K108	R:R:V51	4.55	No	No	3	5	5
7	R:R:I301	R:R:I54	5.89	No	No	0	5	5
8	R:R:A105	R:R:Y55	4	No	Yes	0	7	7
9	R:R:K108	R:R:Y55	5.97	No	Yes	3	5	7
10	R:R:I304	R:R:Y55	7.25	No	Yes	0	7	7
11	R:R:C308	R:R:V58	5.12	No	No	0	7	7
12	R:R:F59	R:R:L60	4.87	No	No	0	7	4
13	R:R:F59	R:R:L63	4.87	No	No	0	7	5
14	R:R:F59	R:R:P102	8.67	No	No	0	7	9
15	R:R:S307	R:R:S62	4.89	No	No	0	8	8
16	R:R:G65	R:R:P311	4.06	No	No	0	7	9
17	R:R:D94	R:R:N66	5.39	No	Yes	0	9	9
18	R:R:N66	R:R:P311	11.4	Yes	No	0	9	9
19	R:R:L325	R:R:L68	6.92	No	No	0	6	6
20	R:R:P311	R:R:V69	3.53	No	No	0	9	8
21	R:R:V69	R:R:Y314	5.05	No	Yes	1	8	9
22	R:R:F321	R:R:V69	5.24	Yes	No	1	8	8
23	R:R:F321	R:R:V72	7.87	Yes	Yes	0	8	7
24	R:R:I73	R:R:L88	11.42	No	No	0	6	5
25	R:R:I73	W:W:?1	5.03	No	Yes	0	6	0
26	R:R:L74	R:R:L88	6.92	No	No	0	2	5
27	R:R:I328	R:R:Y75	12.09	No	No	0	5	4
28	R:R:I331	R:R:Y75	3.63	No	No	4	2	4
29	R:R:H332	R:R:Y75	5.44	No	No	4	3	4
30	R:R:R77	R:R:R80	5.33	No	No	0	6	7
31	R:R:D84	R:R:R80	3.57	Yes	No	0	8	7
32	R:R:D84	R:R:S81	8.83	Yes	No	1	8	7
33	R:R:S81	W:W:?1	10.59	No	Yes	1	7	0
34	R:R:V82	R:R:Y86	5.05	Yes	Yes	1	7	7
35	R:R:D143	R:R:V82	10.22	No	Yes	0	8	7
36	R:R:R159	R:R:V82	3.92	No	Yes	0	3	7
37	R:R:V162	R:R:V82	4.81	Yes	Yes	1	7	7
38	R:R:I140	R:R:T83	6.08	Yes	No	1	9	7
39	R:R:R144	R:R:T83	5.17	Yes	No	1	9	7
40	R:R:T83	W:W:?1	11.27	No	Yes	1	7	0
41	R:R:D84	R:R:K320	8.3	Yes	No	1	8	6
42	R:R:D84	W:W:?1	19.15	Yes	Yes	1	8	0
43	R:R:L136	R:R:Y86	3.52	No	Yes	0	8	7
44	R:R:C139	R:R:Y86	9.41	No	Yes	0	5	7
45	R:R:I140	R:R:Y86	4.84	Yes	Yes	1	9	7
46	R:R:V162	R:R:Y86	3.79	Yes	Yes	1	7	7
47	R:R:I165	R:R:Y86	7.25	No	Yes	0	5	7
48	R:R:L87	R:R:Y314	5.86	No	Yes	1	7	9
49	R:R:L87	W:W:?1	4.07	No	Yes	1	7	0
50	R:R:L136	R:R:N89	5.49	No	No	0	8	9
51	R:R:C166	R:R:N89	9.45	No	No	0	7	9
52	R:R:N89	R:R:W170	5.65	No	Yes	0	9	9
53	R:R:L90	R:R:N310	4.12	No	Yes	0	9	9
54	R:R:L92	R:R:L96	4.15	No	No	0	6	7
55	R:R:L92	R:R:W170	6.83	No	Yes	0	6	9
56	R:R:D94	R:R:H306	6.3	No	Yes	0	9	9
57	R:R:D94	R:R:S307	5.89	No	No	0	9	8
58	R:R:F97	R:R:N129	15.71	No	No	0	6	8
59	R:R:F97	R:R:S307	7.93	No	No	0	6	8
60	R:R:T100	R:R:W104	3.64	No	Yes	2	7	6
61	R:R:T100	R:R:V122	11.11	No	No	2	7	5
62	R:R:L125	R:R:T100	4.42	No	No	0	4	7
63	R:R:I304	R:R:L101	4.28	No	No	0	7	8
64	R:R:I103	R:R:W112	3.52	No	Yes	0	6	9
65	R:R:S107	R:R:W104	4.94	No	Yes	0	5	6
66	R:R:V122	R:R:W104	6.13	No	Yes	2	5	6
67	R:R:K126	R:R:W104	6.96	No	Yes	0	6	6
68	R:R:S107	R:R:W112	4.94	No	Yes	0	5	9
69	R:R:E300	R:R:K108	4.05	No	No	0	5	5
70	R:R:N110	R:R:V109	7.39	No	No	0	4	4
71	R:R:F114	R:R:W112	15.03	Yes	Yes	2	6	9
72	R:R:L118	R:R:W112	4.56	No	Yes	2	6	9
73	R:R:C119	R:R:W112	3.92	No	Yes	2	9	9
74	R:R:V122	R:R:W112	4.9	No	Yes	2	5	9
75	R:R:C196	R:R:W112	11.75	No	Yes	2	9	9
76	R:R:F114	R:R:L118	3.65	Yes	No	2	6	6
77	R:R:R185	R:R:T116	3.88	No	No	0	4	3
78	R:R:T116	R:R:T186	4.71	No	No	0	3	4
79	R:R:F117	R:R:V121	7.87	No	No	0	1	5
80	R:R:C119	R:R:C196	5.46	No	No	2	9	9
81	R:R:R184	R:R:S123	9.22	Yes	No	0	5	5
82	R:R:L124	R:R:L174	4.15	No	No	0	6	5
83	R:R:L124	R:R:L181	5.54	No	No	0	6	5
84	R:R:K126	R:R:R184	6.19	No	Yes	0	6	5
85	R:R:E127	R:R:Y131	10.1	No	Yes	0	4	7
86	R:R:E127	R:R:V180	7.13	No	No	0	4	4
87	R:R:S173	R:R:V128	6.46	No	No	0	7	5
88	R:R:F130	R:R:Y131	5.16	Yes	Yes	0	7	7
89	R:R:F130	R:R:I134	5.02	Yes	No	0	7	8
90	R:R:F130	R:R:W264	16.04	Yes	No	0	7	8
91	R:R:F130	R:R:N268	6.04	Yes	No	0	7	8
92	R:R:L176	R:R:Y131	15.24	No	Yes	6	4	7
93	R:R:P215	R:R:Y131	6.95	No	Yes	6	5	7
94	R:R:G133	R:R:S132	3.71	No	No	0	9	6
95	R:R:S132	R:R:W170	3.71	No	Yes	0	6	9
96	R:R:S132	R:R:S173	4.89	No	No	0	6	7
97	R:R:I134	R:R:P223	5.08	No	Yes	0	8	9
98	R:R:F260	R:R:I134	7.54	Yes	No	0	9	8
99	R:R:I169	R:R:W135	4.7	No	No	0	6	6
100	R:R:L172	R:R:W135	6.83	No	No	0	4	6
101	R:R:P223	R:R:W135	20.27	Yes	No	0	9	6
102	R:R:F260	R:R:L137	8.53	Yes	No	0	9	8
103	R:R:I140	R:R:Y231	3.63	Yes	Yes	1	9	9
104	R:R:I140	R:R:I253	4.42	Yes	Yes	1	9	7
105	R:R:S141	R:R:Y231	13.99	No	Yes	0	9	9
106	R:R:D143	R:R:R144	5.96	No	Yes	0	8	9
107	R:R:D143	R:R:T154	7.23	No	No	0	8	5
108	R:R:A147	R:R:R144	4.15	No	Yes	0	8	9
109	R:R:M250	R:R:R144	7.44	No	Yes	0	5	9
110	R:R:R144	W:W:?1	9.29	Yes	Yes	1	9	0
111	R:R:V149	R:R:Y145	8.83	No	Yes	7	7	8
112	R:R:H150	R:R:Y145	10.89	No	Yes	7	6	8
113	R:R:C230	R:R:Y145	8.06	No	Yes	0	7	8
114	R:R:T234	R:R:Y145	3.75	No	Yes	0	8	8
115	R:R:L146	R:R:T154	4.42	No	No	0	5	5
116	R:R:I148	R:R:T234	6.08	No	No	0	8	8
117	R:R:I148	R:R:L238	4.28	No	No	0	8	8
118	R:R:I148	R:R:K246	10.18	No	No	0	8	7
119	R:R:H150	R:R:V149	6.92	No	No	7	6	7
120	R:R:T237	R:R:V149	9.52	No	No	0	5	7
121	R:R:R153	R:R:T156	6.47	No	No	0	5	2
122	R:R:L155	R:R:V162	4.47	No	Yes	0	4	7
123	R:R:I165	R:R:L155	4.28	No	No	0	5	4
124	R:R:K158	R:R:Y160	10.75	No	No	8	6	5
125	R:R:K158	R:R:L161	7.05	No	No	8	6	4
126	R:R:L161	R:R:Y160	16.41	No	No	8	4	5
127	R:R:F164	R:R:Y160	4.13	No	No	0	3	5
128	R:R:L176	R:R:P215	4.93	No	No	6	4	5
129	R:R:L211	R:R:P179	9.85	No	No	0	4	8
130	R:R:R184	R:R:V180	3.92	Yes	No	5	5	4
131	R:R:E198	R:R:V180	4.28	Yes	No	5	5	4
132	R:R:F183	R:R:L182	4.87	Yes	No	0	5	4
133	R:R:E198	R:R:F183	7	Yes	Yes	0	5	5
134	R:R:F183	R:R:R208	20.31	Yes	No	0	5	4
135	R:R:F183	R:R:L211	4.87	Yes	No	0	5	4
136	R:R:E198	R:R:R184	5.82	Yes	Yes	5	5	5
137	R:R:T186	R:R:Y188	4.99	No	No	0	4	1
138	R:R:V187	R:R:Y197	13.88	No	Yes	0	3	3
139	R:R:P194	R:R:Y188	5.56	No	No	0	5	1
140	R:R:A195	R:R:Y197	4	No	Yes	0	3	3
141	R:R:E198	R:R:R212	8.14	Yes	No	0	5	5
142	R:R:D199	R:R:R208	3.57	No	No	0	4	4
143	R:R:I213	R:R:M209	4.37	No	No	0	4	3
144	R:R:L271	R:R:R212	4.86	No	No	0	6	5
145	R:R:I213	R:R:Q216	4.12	No	No	0	4	5
146	R:R:I221	R:R:S217	6.19	No	No	0	4	4
147	R:R:F218	R:R:V222	3.93	No	No	0	4	5
148	R:R:G219	R:R:P223	4.06	No	Yes	0	5	9
149	R:R:F220	R:R:I221	3.77	No	No	0	8	4
150	R:R:F220	R:R:N268	8.46	No	No	0	8	8
151	R:R:P223	R:R:V222	3.53	Yes	No	0	9	5
152	R:R:L224	R:R:L228	4.15	No	No	0	7	4
153	R:R:F229	R:R:L225	3.65	No	No	0	4	3
154	R:R:M227	R:R:Y231	5.99	No	Yes	0	8	9
155	R:R:I253	R:R:Y231	3.63	Yes	Yes	1	7	9
156	R:R:F254	R:R:Y231	6.19	No	Yes	0	4	9
157	R:R:V257	R:R:Y231	10.09	No	Yes	0	7	9
158	R:R:F239	R:R:L235	6.09	No	No	0	5	4
159	R:R:F254	R:R:L235	9.74	No	No	0	4	4
160	R:R:K240	R:R:T237	4.5	No	No	0	5	5
161	R:R:H247	R:R:L238	6.43	No	No	0	5	8
162	R:R:R248	R:R:R251	13.86	No	No	0	7	5
163	R:R:E249	R:R:K320	6.75	No	No	1	7	6
164	R:R:E249	W:W:?1	10.91	No	Yes	1	7	0
165	R:R:I253	R:R:M250	5.83	Yes	No	0	7	5
166	R:R:F254	R:R:M250	7.46	No	No	0	4	5
167	R:R:I317	R:R:R251	3.76	Yes	No	0	6	5
168	R:R:G318	R:R:V252	3.68	No	No	0	7	7
169	R:R:I253	W:W:?1	4.2	Yes	Yes	1	7	0
170	R:R:N310	R:R:V256	5.91	Yes	No	1	9	8
171	R:R:V256	R:R:Y314	3.79	No	Yes	1	8	9
172	R:R:L258	R:R:L262	4.15	No	No	0	5	5
173	R:R:I259	R:R:L309	4.28	No	No	0	6	6
174	R:R:F260	R:R:W264	10.02	Yes	No	0	9	8
175	R:R:F260	R:R:H306	11.31	Yes	Yes	0	9	9
176	R:R:C263	R:R:H306	7.37	No	Yes	0	7	9
177	R:R:A303	R:R:W264	7.78	No	No	0	7	8
178	R:R:L265	R:R:L269	5.54	No	No	0	6	6
179	R:R:L271	R:R:Y267	4.69	No	Yes	0	6	7
180	R:R:L296	R:R:Y267	4.69	No	Yes	0	5	7
181	R:R:T299	R:R:Y267	7.49	No	Yes	0	6	7
182	R:R:E300	R:R:Y267	4.49	No	Yes	0	5	7
183	R:R:L296	R:R:V270	4.47	No	No	0	5	4
184	R:R:T299	R:R:V270	4.76	No	No	0	6	4
185	R:R:D274	R:R:I292	12.59	No	No	0	4	5
186	R:R:D274	R:R:L296	4.07	No	No	0	4	5
187	R:R:L276	R:R:T279	4.42	No	No	0	4	1
188	R:R:M277	R:R:R289	3.72	No	No	0	4	3
189	R:R:H291	R:R:R289	6.77	No	No	0	3	3
190	R:R:H306	R:R:N310	7.65	Yes	Yes	0	9	9
191	R:R:N310	R:R:Y314	8.14	Yes	Yes	1	9	9
192	R:R:F321	R:R:Y314	4.13	Yes	Yes	1	8	9
193	R:R:Y314	W:W:?1	4.82	Yes	Yes	1	9	0
194	R:R:Q319	R:R:R322	7.01	No	No	0	5	8
195	R:R:H323	R:R:Q319	3.71	No	No	0	4	5
196	R:R:K320	W:W:?1	30.68	No	Yes	1	6	0
197	R:R:F321	W:W:?1	4.3	Yes	Yes	1	8	0
198	R:R:L329	R:R:L334	8.3	No	No	0	6	1
199	R:R:H332	R:R:I331	9.28	No	No	4	3	2
200	R:R:Q216	R:R:R212	3.5	No	No	0	5	5
201	R:R:V252	W:W:?1	3.5	No	Yes	0	7	0
202	R:R:P266	R:R:T299	3.5	No	No	0	9	6
203	R:R:C230	R:R:S141	3.44	No	No	0	7	9
204	R:R:A98	R:R:S62	3.42	No	No	0	5	8
205	R:R:S76	R:R:V78	3.23	No	No	0	4	5
206	R:R:V162	R:R:V85	3.21	Yes	No	0	7	6
207	R:R:C308	R:R:L61	3.17	No	No	0	7	5
208	R:R:A91	R:R:N66	3.13	No	Yes	0	8	9
209	R:R:I335	R:R:S336	3.1	No	No	0	4	8
210	R:R:I304	R:R:V58	3.07	No	No	0	7	7
211	R:R:I328	R:R:V72	3.07	No	Yes	0	5	7
212	R:R:I317	R:R:V252	3.07	Yes	No	0	6	7
213	R:R:L305	R:R:V58	2.98	No	No	0	5	7
214	R:R:L325	R:R:V72	2.98	No	Yes	0	6	7
215	R:R:L124	R:R:V128	2.98	No	No	0	6	5
216	R:R:N191	R:R:S190	2.98	No	No	0	2	2
217	R:R:L261	R:R:V257	2.98	No	No	0	6	7
218	R:R:L146	R:R:T152	2.95	No	No	0	5	5
219	R:R:I259	R:R:I313	2.94	No	No	0	6	7
220	R:R:I313	R:R:I317	2.94	No	Yes	9	7	6
221	R:R:L88	R:R:M70	2.83	No	No	0	5	6
222	R:R:L92	R:R:M70	2.83	No	No	0	6	6
223	R:R:L57	R:R:L61	2.77	No	No	0	5	5
224	R:R:A106	R:R:F114	2.77	No	Yes	0	4	6
225	R:R:L155	R:R:L161	2.77	No	No	0	4	4
226	R:R:L95	R:R:N66	2.75	No	Yes	0	7	9
227	R:R:L272	R:R:Q216	2.66	No	No	0	5	5
228	R:R:F50	R:R:V51	2.62	No	No	0	5	5
229	R:R:A93	R:R:W170	2.59	No	Yes	0	8	9
230	R:R:F114	R:R:I113	2.51	Yes	No	0	6	3
231	R:R:I292	R:R:R289	2.51	No	No	0	5	3
232	R:R:K240	R:R:R236	2.48	No	No	0	5	4
233	R:R:F117	R:R:L118	2.44	No	No	0	1	6
234	R:R:F220	R:R:L265	2.44	No	No	0	8	6
235	R:R:F316	R:R:L312	2.44	No	No	0	6	6
236	R:R:T186	R:R:W112	2.43	No	Yes	0	4	9
237	R:R:L210	R:R:W207	2.28	No	No	0	2	3
238	R:R:F233	R:R:Y145	2.06	No	Yes	0	4	8
239	R:R:R184	R:R:Y197	2.06	Yes	Yes	0	5	3
240	R:R:G111	R:R:P194	2.03	No	No	0	4	5
241	R:R:A138	R:R:P223	1.87	No	Yes	0	7	9
242	R:R:G111	R:R:S193	1.86	No	No	0	4	3
243	R:R:G324	R:R:V72	1.84	No	Yes	0	5	7
244	R:R:G79	R:R:V78	1.84	No	No	0	6	5
245	R:R:G244	R:R:K246	1.74	No	No	0	4	7
246	R:R:G324	R:R:K327	1.74	No	No	0	5	4
247	R:R:G65	R:R:L64	1.71	No	No	0	7	4
248	R:R:G171	R:R:L174	1.71	No	No	0	4	5
249	R:R:A105	R:R:V52	1.7	No	No	0	7	5
250	R:R:G111	R:R:N110	1.7	No	No	0	4	4
251	R:R:A177	R:R:V128	1.7	No	No	0	7	5
252	R:R:L101	R:R:P102	1.64	No	No	0	8	9
253	R:R:L178	R:R:P179	1.64	No	No	0	3	8
254	R:R:L214	R:R:P215	1.64	No	No	0	3	5
255	R:R:C230	R:R:I226	1.64	No	No	0	7	6
256	R:R:L302	R:R:P266	1.64	No	No	0	7	9
257	R:R:A255	R:R:I313	1.62	No	No	9	5	7
258	R:R:A255	R:R:I317	1.62	No	Yes	9	5	6
259	R:R:A273	R:R:I292	1.62	No	No	0	5	5
260	R:R:G333	R:R:H332	1.59	No	No	0	3	3
261	R:R:I226	R:R:V142	1.54	No	No	0	6	6
262	R:R:L63	R:R:S67	1.5	No	No	0	5	3
263	R:R:L95	R:R:S67	1.5	No	No	0	7	3
264	R:R:L71	R:R:V72	1.49	No	Yes	0	3	7
265	R:R:I53	R:R:I54	1.47	No	No	0	5	5
266	R:R:I221	R:R:L225	1.43	No	No	0	4	3
267	R:R:G115	R:R:W112	1.41	No	Yes	0	8	9
268	R:R:K120	R:R:L181	1.41	No	No	0	7	5
269	R:R:A315	R:R:F321	1.39	No	Yes	0	7	8
270	R:R:L312	R:R:L61	1.38	No	No	0	6	5
271	R:R:L96	R:R:L99	1.38	No	No	0	7	4
272	R:R:L224	R:R:L261	1.38	No	No	0	7	6
273	R:R:L272	R:R:L276	1.38	No	No	0	5	4
274	R:R:L325	R:R:L329	1.38	No	No	0	6	6
275	R:R:L326	R:R:L329	1.38	No	No	0	4	6
276	R:R:S189	R:R:Y197	1.27	No	Yes	0	1	3
277	R:R:H247	R:R:Q245	1.24	No	No	0	5	4
278	R:R:D297	R:R:R294	1.19	No	No	0	4	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y55	6.1975	4	3	7
2	R:R:N66	5.6675	4	0	9
3	R:R:V72	3.45	5	0	7
4	R:R:V82	6	4	1	7
5	R:R:D84	9.9625	4	1	8
6	R:R:Y86	5.64333	6	1	7
7	R:R:W104	5.4175	4	2	6
8	R:R:W112	5.82889	9	2	9
9	R:R:F114	5.99	4	2	6
10	R:R:F130	8.065	4	0	7
11	R:R:Y131	9.3625	4	6	7
12	R:R:I140	4.7425	4	1	9
13	R:R:R144	6.402	5	1	9
14	R:R:Y145	6.718	5	7	8
15	R:R:V162	4.07	4	1	7
16	R:R:W170	4.695	4	0	9
17	R:R:F183	9.2625	4	0	5
18	R:R:R184	5.442	5	5	5
19	R:R:Y197	5.3025	4	0	3
20	R:R:E198	6.31	4	5	5
21	R:R:P223	6.962	5	0	9
22	R:R:Y231	7.25333	6	1	9
23	R:R:I253	4.52	4	1	7
24	R:R:F260	9.35	4	0	9
25	R:R:Y267	5.34	4	0	7
26	R:R:H306	8.1575	4	0	9
27	R:R:N310	6.455	4	1	9
28	R:R:Y314	5.29833	6	1	9
29	R:R:I317	2.8475	4	9	6
30	R:R:F321	4.586	5	1	8
31	W:W:?1	9.8175	12	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I304	R:R:Y55	13.7829	7.25	No	Yes	0	7	7
2	R:R:F59	R:R:P102	19.9074	8.67	No	No	0	7	9
3	R:R:L101	R:R:P102	19.2245	1.64	No	No	0	8	9
4	R:R:I304	R:R:L101	18.5718	4.28	No	No	0	7	8
5	R:R:F59	R:R:L63	21.273	4.87	No	No	0	7	5
6	R:R:L63	R:R:S67	22.2687	1.5	No	No	0	5	3
7	R:R:L95	R:R:S67	23.4869	1.5	No	No	0	7	3
8	R:R:L95	R:R:N66	24.7624	2.75	No	Yes	0	7	9
9	R:R:N66	R:R:P311	25.0301	11.4	Yes	No	0	9	9
10	R:R:P311	R:R:V69	25.4271	3.53	No	No	0	9	8
11	R:R:F321	R:R:V69	13.801	5.24	Yes	No	1	8	8
12	R:R:F321	R:R:V72	15.8886	7.87	Yes	Yes	0	8	7
13	R:R:V69	R:R:Y314	12.9106	5.05	No	Yes	1	8	9
14	R:R:Y314	W:W:?1	93.1206	4.82	Yes	Yes	1	9	0
15	R:R:I73	W:W:?1	19.2366	5.03	No	Yes	0	6	0
16	R:R:F321	W:W:?1	17.913	4.3	Yes	Yes	1	8	0
17	R:R:I73	R:R:L88	18.2198	11.42	No	No	0	6	5
18	R:R:R144	W:W:?1	18.4334	9.29	Yes	Yes	1	9	0
19	R:R:D143	R:R:R144	13.8972	5.96	No	Yes	0	8	9
20	R:R:T83	W:W:?1	18.7793	11.27	No	Yes	1	7	0
21	R:R:I140	R:R:T83	18.653	6.08	Yes	No	1	9	7
22	R:R:I140	R:R:Y86	37.5105	4.84	Yes	Yes	1	9	7
23	R:R:I253	W:W:?1	49.1126	4.2	Yes	Yes	1	7	0
24	R:R:I140	R:R:I253	18.0063	4.42	Yes	Yes	1	9	7
25	R:R:V162	R:R:Y86	14.3184	3.79	Yes	Yes	1	7	7
26	R:R:I165	R:R:Y86	12.0623	7.25	No	Yes	0	5	7
27	R:R:L88	R:R:M70	15.9758	2.83	No	No	0	5	6
28	R:R:L92	R:R:M70	14.9801	2.83	No	No	0	6	6
29	R:R:L92	R:R:W170	12.2819	6.83	No	Yes	0	6	9
30	R:R:D94	R:R:H306	11.7736	6.3	No	Yes	0	9	9
31	R:R:H306	R:R:N310	93.8365	7.65	Yes	Yes	0	9	9
32	R:R:L271	R:R:Y267	22.8282	4.69	No	Yes	0	6	7
33	R:R:L271	R:R:R212	23.8238	4.86	No	No	0	6	5
34	R:R:E198	R:R:R212	31.4132	8.14	Yes	No	0	5	5
35	R:R:K126	R:R:R184	56.8343	6.19	No	Yes	0	6	5
36	R:R:K126	R:R:W104	55.7484	6.96	No	Yes	0	6	6
37	R:R:V122	R:R:W104	26.0588	6.13	No	Yes	2	5	6
38	R:R:S107	R:R:W112	25.006	4.94	No	Yes	0	5	9
39	R:R:S107	R:R:W104	26.2062	4.94	No	Yes	0	5	6
40	R:R:V122	R:R:W112	25.1203	4.9	No	Yes	2	5	9
41	R:R:T186	R:R:W112	22.9816	2.43	No	Yes	0	4	9
42	R:R:T186	R:R:Y188	15.3742	4.99	No	No	0	4	1
43	R:R:P194	R:R:Y188	12.8264	5.56	No	No	0	5	1
44	R:R:G111	R:R:P194	10.2725	2.03	No	No	0	4	5
45	R:R:S132	R:R:W170	11.6081	3.71	No	Yes	0	6	9
46	R:R:E127	R:R:V180	87.4925	7.13	No	No	0	4	4
47	R:R:E198	R:R:V180	31.726	4.28	Yes	No	5	5	4
48	R:R:E127	R:R:Y131	88.2926	10.1	No	Yes	0	4	7
49	R:R:F130	R:R:Y131	91.3368	5.16	Yes	Yes	0	7	7
50	R:R:F130	R:R:I134	50.0993	5.02	Yes	No	0	7	8
51	R:R:F130	R:R:W264	47.9004	16.04	Yes	No	0	7	8
52	R:R:F130	R:R:N268	10.8802	6.04	Yes	No	0	7	8
53	R:R:F260	R:R:I134	51.9943	7.54	Yes	No	0	9	8
54	R:R:F260	R:R:W264	48.3215	10.02	Yes	No	0	9	8
55	R:R:F260	R:R:H306	100	11.31	Yes	Yes	0	9	9
56	R:R:I253	R:R:Y231	27.1087	3.63	Yes	Yes	1	7	9
57	R:R:S141	R:R:Y231	21.655	13.99	No	Yes	0	9	9
58	R:R:C230	R:R:S141	20.5029	3.44	No	No	0	7	9
59	R:R:C230	R:R:Y145	17.0106	8.06	No	Yes	0	7	8
60	R:R:L155	R:R:V162	15.3441	4.47	No	Yes	0	4	7
61	R:R:I165	R:R:L155	10.1853	4.28	No	No	0	5	4
62	R:R:L155	R:R:L161	20.5962	2.77	No	No	0	4	4
63	R:R:L161	R:R:Y160	10.3026	16.41	No	No	8	4	5
64	R:R:V252	W:W:?1	11.2141	3.5	No	Yes	0	7	0
65	R:R:L296	R:R:Y267	10.5192	4.69	No	Yes	0	5	7
66	R:R:R184	R:R:V180	55.1197	3.92	Yes	No	5	5	4
67	R:R:F321	R:R:Y314	10.3387	4.13	Yes	Yes	1	8	9
68	R:R:N310	R:R:Y314	92.537	8.14	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:V69	R:R:Y314	5.05	1	No	Yes	8	9	2	1
R:R:F321	R:R:V69	5.24	1	Yes	No	8	8	1	2
R:R:F321	R:R:V72	7.87	1	Yes	Yes	8	7	1	2
R:R:I73	R:R:L88	11.42	0	No	No	6	5	1	2
R:R:I73	W:W:?1	5.03	0	No	Yes	6	0	1	0
R:R:D84	R:R:R80	3.57	1	Yes	No	8	7	1	2
R:R:D84	R:R:S81	8.83	1	Yes	No	8	7	1	1
R:R:S81	W:W:?1	10.59	1	No	Yes	7	0	1	0
R:R:I140	R:R:T83	6.08	1	Yes	No	9	7	2	1
R:R:R144	R:R:T83	5.17	1	Yes	No	9	7	1	1
R:R:T83	W:W:?1	11.27	1	No	Yes	7	0	1	0
R:R:D84	R:R:K320	8.3	1	Yes	No	8	6	1	1
R:R:D84	W:W:?1	19.15	1	Yes	Yes	8	0	1	0
R:R:L87	R:R:Y314	5.86	1	No	Yes	7	9	1	1
R:R:L87	W:W:?1	4.07	1	No	Yes	7	0	1	0
R:R:I140	R:R:Y231	3.63	1	Yes	Yes	9	9	2	2
R:R:I140	R:R:I253	4.42	1	Yes	Yes	9	7	2	1
R:R:D143	R:R:R144	5.96	0	No	Yes	8	9	2	1
R:R:A147	R:R:R144	4.15	0	No	Yes	8	9	2	1
R:R:M250	R:R:R144	7.44	0	No	Yes	5	9	2	1
R:R:R144	W:W:?1	9.29	1	Yes	Yes	9	0	1	0
R:R:I253	R:R:Y231	3.63	1	Yes	Yes	7	9	1	2
R:R:E249	R:R:K320	6.75	1	No	No	7	6	1	1
R:R:E249	W:W:?1	10.91	1	No	Yes	7	0	1	0
R:R:I253	R:R:M250	5.83	1	Yes	No	7	5	1	2
R:R:G318	R:R:V252	3.68	0	No	No	7	7	2	1
R:R:I253	W:W:?1	4.2	1	Yes	Yes	7	0	1	0
R:R:N310	R:R:V256	5.91	1	Yes	No	9	8	2	2
R:R:V256	R:R:Y314	3.79	1	No	Yes	8	9	2	1
R:R:N310	R:R:Y314	8.14	1	Yes	Yes	9	9	2	1
R:R:F321	R:R:Y314	4.13	1	Yes	Yes	8	9	1	1
R:R:Y314	W:W:?1	4.82	1	Yes	Yes	9	0	1	0
R:R:K320	W:W:?1	30.68	1	No	Yes	6	0	1	0
R:R:F321	W:W:?1	4.3	1	Yes	Yes	8	0	1	0
R:R:V252	W:W:?1	3.5	0	No	Yes	7	0	1	0
R:R:I317	R:R:V252	3.07	9	Yes	No	6	7	2	1
R:R:A315	R:R:F321	1.39	0	No	Yes	7	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
73.33	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
53.85	Single	5T1A	PubChem 12093170	5T1A-CCR2-BMS-681-PubChem 12093170
53.33	Single	6QZH	Cmp2105; Na	6QZH-CCR7-Cmp2105; Na
37.50	Single	5X7D	Cmpd-15	5X7D-β₂-S-Carazolol-Cmpd-15
31.82	Single	8FN0	SBI-553	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
27.78	Single	8JPF	SBI-553	8JPF-NTS₁-Neurotensin-SBI-553
26.09	Single	8ZYT	SBI-553	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
23.81	Single	8ZYU	SBI-553	8ZYU-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
21.43	Single	3VG9	Antibody	3VG9-A_2A-ZM-241385-Antibody
21.05	Single	8JPC	SBI-553; GDP; Mg	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
19.35	Single	3VGA	Antibody	3VGA-A_2A-ZM-241385-Antibody
19.05	Single	8JPB	SBI-553; GDP; Mg	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
18.18	Single	8ZYY	SBI-553	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
15.00	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
14.29	Single	8GW8	PCO371	8GW8-PTH1-PCO371-Gs/β1/γ2
13.04	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
13.04	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
9.52	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
8.70	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
8.00	Single	6LN2	PF-06372222	6LN2-GLP-1-PF-06372222
6.67	Single	4PXF	Octyl-Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl-β-D-Glucopyranoside-Arrestin1 Finger Loop
5.88	Single	7EB2	rac-BHFF	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
5.56	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
5.56	Single	8XQP	Aristolochic acid A	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.26	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
5.26	Single	6KK7	PF-06372222	6KK7-GLP-1-PF-06372222
5.26	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
5.00	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
5.00	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
5.00	Single	6KJV	PF-06372222	6KJV-GLP-1-PF-06372222
5.00	Single	6KK1	PF-06372222	6KK1-GLP-1-PF-06372222
5.00	Single	7C7Q	BHFF	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
5.00	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/β1/γ2
5.00	Single	8XQN	Aristolochic acid A	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
5.00	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
4.76	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
4.76	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
4.76	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.76	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
4.55	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
4.55	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
4.35	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
4.00	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203

PDB Summary
PDB	6LFL
Class	A
SubFamily	Protein
Type	Chemokine
SubType	CXCR2
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	PubChem 153466996
Protein Partners	-
PDB Resolution	3.2
Date	2020-09-02
D.O.I.	doi.org/10.1038/s41586-020-2492-5

Net Summary
I_min	3.52
Number of Linked Nodes	257
Number of Links	278
Number of Hubs	31
Number of Links mediated by Hubs	127
Number of Communities	9
Number of Nodes involved in Communities	48
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	69
Number Of Links MetaPath	68
Number of Shortest Paths	59669
Length Of Smallest Path	3
Average Path Length	15.6488
Length of Longest Path	32
Minimum Path Strength	1.38
Average Path Strength	6.3365
Maximum Path Strength	20.975
Minimum Path Correlation	0.7
Average Path Correlation	0.925126
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	42.6159
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.9731
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• G protein-coupled chemoattractant receptor activity • molecular transducer activity • interleukin-8 receptor activity • C-X-C chemokine receptor activity • chemokine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cytokine receptor activity • immune receptor activity • C-C chemokine receptor activity • protein binding • binding • chemokine binding • C-X-C chemokine binding • interleukin-8 binding • cytokine binding • C-C chemokine binding • UDP-glycosyltransferase activity • alpha-1,4-glucan glucosyltransferase (NDP-glucose donor) activity • glycosyltransferase activity • alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity • transferase activity • glucosyltransferase activity • hexosyltransferase activity • catalytic activity • UDP-glucosyltransferase activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • localization • import into cell • receptor internalization • transport • cellular process • receptor-mediated endocytosis • endocytosis • establishment of localization • vesicle-mediated transport • response to stimulus • immune response
Gene Ontology	Biological Process	• positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • localization • import into cell • receptor internalization • transport • cellular process • receptor-mediated endocytosis • endocytosis • establishment of localization • vesicle-mediated transport • response to stimulus • immune response • immune system process • regulation of biological process • regulation of cellular process • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of biological process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • negative regulation of cellular process • apoptotic process • programmed cell death • neutrophil activation • multicellular organismal process • cell activation • myeloid leukocyte activation • granulocyte activation • leukocyte activation • cell chemotaxis • cellular response to stimulus • chemotaxis • neutrophil chemotaxis • response to external stimulus • neutrophil migration • granulocyte migration • leukocyte migration • cellular response to chemical stimulus • taxis • granulocyte chemotaxis • response to chemical • myeloid leukocyte migration • cell migration • cell motility • leukocyte chemotaxis • locomotion • signaling • intracellular signal transduction • cell communication • calcium-mediated signaling • intracellular signaling cassette • signal transduction • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • positive regulation of biological process • positive regulation of cellular process • dendritic cell chemotaxis • dendritic cell migration • mononuclear cell migration • cell surface receptor signaling pathway • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • defense response • response to stress • cellular defense response • inflammatory response • response to cytokine • cytokine-mediated signaling pathway • response to peptide • cellular response to interleukin-8 • response to interleukin-8 • cellular response to cytokine stimulus • interleukin-8-mediated signaling pathway • cell periphery • cellular anatomical structure • cell surface • membrane • plasma membrane • external side of plasma membrane • side of membrane • membrane-bounded organelle • intracellular anatomical structure • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • mast cell granule
Gene Ontology	Cellular Component	• cell periphery • cellular anatomical structure • cell surface • membrane • plasma membrane • external side of plasma membrane • side of membrane • membrane-bounded organelle • intracellular anatomical structure • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • mast cell granule • organelle • cytoplasm • lysosome • mitotic spindle • cytoskeleton • spindle • membraneless organelle • intracellular membraneless organelle • microtubule cytoskeleton • nucleus • membrane-enclosed lumen • intracellular organelle lumen • nucleoplasm • organelle lumen • nuclear lumen • intracellular vesicle • endomembrane system • cytoplasmic vesicle membrane • bounding membrane of organelle • vesicle membrane • cytoplasmic vesicle • secretory granule • secretory vesicle • vesicle • organelle membrane • secretory granule membrane
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Type B glycosyltransferase-like
SCOP2	Family Identifier	• G protein-coupled receptor-like • Type B glycosyltransferase-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	EBX
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	EBX
Name	4-[[3,4-bis(oxidanylidene)-2-[[(1~{R})-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-~{N},~{N}-dimethyl-3-oxidanyl-pyridine-2-carboxamide
Synonyms
Identifier
Formula	C22 H26 N4 O5
Molecular Weight	426.466
SMILES
PubChem	153466996
Formal Charge	0
Total Atoms	57
Total Chiral Atoms	1
Total Bonds	59
Total Aromatic Bonds	11


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P25025
Sequence	>6LFL_Chain_R I N K Y F V V I I Y A L V F L L S L L G N S L V M L V I L Y S R V G R S V T D V Y L L N L A L A D L L F A L T L P I W A A S K V N G W I F G T F L C K V V S L L K E V N F Y S G I W L L A C I S V D R Y L A I V H A T R T L T Q K R Y L V K F I C L S I W G L S L L L A L P V L L F R R T V Y S S N V S P A C Y E D A N W R M L L R I L P Q S F G F I V P L L I M L F C Y G F T L R T L F K A G Q K H R E M R V I F A V V L I F L L C W L P Y N L V L L A D T L M R T R N H I D R A L D A T E I L A I L H S C L N P L I Y A F I G Q K F R H G L L K I L A I H G L I S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6LFL	A	Protein	Chemokine	CXCR2	Homo sapiens	-	PubChem 153466996	-	3.2	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFM	A	Protein	Chemokine	CXCR2	Homo sapiens	Interleukin-8	-	Gi1/β1/γ2	3.5	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFM (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	Interleukin-8	-		3.5	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFO	A	Protein	Chemokine	CXCR2	Homo sapiens	Interleukin-8	-	Gi1/β1/γ2	3.4	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFO (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	Interleukin-8	-		3.4	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	8XVU	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL2	-	-	3.09	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWA	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL1	-	-	3.48	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWF	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL3	-	-	3.65	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWM	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL6	-	-	3.71	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWN	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-	-	3.29	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWS	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL5	-	-	3.06	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWV	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL1	-	Go/β1/γ2	3.07	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWV (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL1	-		3.07	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX3	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL3	-	Go/β1/γ2	3.38	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX3 (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL3	-		3.38	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX6	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-	Go/β1/γ2	2.99	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX6 (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-		2.99	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX7	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL5	-	Go/β1/γ2	3.32	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX7 (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL5	-		3.32	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXH	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL2	-	Go/β1/γ2	2.8	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXH (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL2	-		2.8	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXR	A	Protein	Chemokine	CXCR2	Homo sapiens	-	-	Go/β1/γ2	3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXR (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	-	-		3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXX	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL6	-	Go/β1/γ2	3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXX (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL6	-		3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024

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