psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:P137	R:R:S136	3.56	No	No	0	3	1
2	R:R:E139	R:R:S136	12.94	No	No	0	2	1
3	R:R:E138	R:R:P137	12.58	No	No	0	2	3
4	R:R:F385	R:R:L144	14.61	No	No	0	6	6
5	R:R:T149	R:R:Y145	11.24	No	No	0	7	5
6	R:R:D198	R:R:Y145	9.2	No	No	0	7	5
7	R:R:Y148	R:R:Y152	19.86	Yes	Yes	4	7	7
8	R:R:V194	R:R:Y148	6.31	No	Yes	4	7	7
9	R:R:S392	R:R:Y148	5.09	Yes	Yes	4	9	7
10	R:R:G151	R:R:S392	3.71	No	Yes	4	8	9
11	R:R:F393	R:R:G151	9.03	No	No	4	7	8
12	R:R:R190	R:R:Y152	5.14	Yes	Yes	0	8	7
13	R:R:V194	R:R:Y152	10.09	No	Yes	4	7	7
14	R:R:S392	R:R:Y152	3.82	Yes	Yes	4	9	7
15	R:R:G395	R:R:S155	3.71	No	No	0	9	9
16	R:R:F156	R:R:V160	6.55	Yes	No	5	7	3
17	R:R:F156	R:R:I188	3.77	Yes	Yes	5	7	7
18	R:R:F156	R:R:L192	4.87	Yes	No	0	7	3
19	R:R:F156	R:R:F195	4.29	Yes	No	5	7	7
20	R:R:F184	R:R:L159	4.87	No	No	0	8	9
21	R:R:I188	R:R:L159	5.71	Yes	No	0	7	9
22	R:R:A399	R:R:L159	3.15	No	No	0	8	9
23	R:R:I188	R:R:V160	3.07	Yes	No	5	7	3
24	R:R:A162	R:R:C403	3.61	No	No	0	9	9
25	R:R:F169	R:R:I165	5.02	Yes	Yes	1	7	8
26	R:R:C403	R:R:I165	4.91	No	Yes	0	9	8
27	R:R:F413	R:R:I165	7.54	No	Yes	1	5	8
28	R:R:L166	R:R:N177	10.98	No	Yes	0	8	9
29	R:R:L166	R:R:L181	6.92	No	No	0	8	6
30	R:R:F184	R:R:L166	4.87	No	No	0	8	8
31	R:R:L167	R:R:L181	6.92	No	No	0	3	6
32	R:R:F169	R:R:L172	4.87	Yes	Yes	1	7	9
33	R:R:E412	R:R:F169	8.16	Yes	Yes	1	8	7
34	R:R:F169	R:R:F413	3.22	Yes	No	1	7	5
35	R:R:H173	R:R:R170	14.67	No	No	0	7	8
36	R:R:E412	R:R:H171	12.31	Yes	No	1	8	7
37	R:R:H171	R:R:K415	9.17	No	No	1	7	7
38	R:R:L172	R:R:N177	4.12	Yes	Yes	1	9	9
39	R:R:L172	R:R:V409	4.47	Yes	No	0	9	9
40	R:R:E412	R:R:L172	3.98	Yes	Yes	1	8	9
41	R:R:H173	R:R:Y178	8.71	No	No	0	7	6
42	R:R:C174	R:R:R176	5.57	No	Yes	1	8	9
43	R:R:C174	R:R:N177	4.72	No	Yes	1	8	9
44	R:R:T175	R:R:Y250	4.99	No	Yes	0	7	8
45	R:R:N177	R:R:R176	9.64	Yes	Yes	1	9	9
46	R:R:H180	R:R:R176	5.64	Yes	Yes	1	9	9
47	R:R:R176	R:R:Y250	4.12	Yes	Yes	0	9	8
48	R:R:H180	R:R:N177	3.83	Yes	Yes	1	9	9
49	R:R:I179	R:R:W243	4.7	No	Yes	0	8	9
50	R:R:E247	R:R:I179	5.47	No	No	0	9	8
51	R:R:I179	R:R:Y250	6.04	No	Yes	0	8	8
52	R:R:E247	R:R:H180	9.85	No	Yes	1	9	9
53	R:R:H180	R:R:Y402	25.04	Yes	Yes	1	9	8
54	R:R:N182	R:R:W243	21.47	No	Yes	8	9	9
55	R:R:N182	R:R:W274	6.78	No	Yes	8	9	9
56	R:R:F187	R:R:L183	3.65	Yes	No	0	8	9
57	R:R:N240	R:R:S186	7.45	No	No	0	9	9
58	R:R:F187	R:R:N240	19.33	Yes	No	0	8	9
59	R:R:F187	R:R:Q394	5.86	Yes	Yes	0	8	9
60	R:R:F187	R:R:G395	4.52	Yes	No	7	8	9
61	R:R:F187	R:R:V398	3.93	Yes	No	7	8	9
62	R:R:C236	R:R:L189	4.76	No	No	0	5	7
63	R:R:R190	R:R:V237	6.54	Yes	No	0	8	6
64	R:R:N240	R:R:R190	9.64	No	Yes	0	9	8
65	R:R:Q394	R:R:R190	4.67	Yes	Yes	0	9	8
66	R:R:L232	R:R:S193	4.5	No	No	0	5	6
67	R:R:M233	R:R:S193	6.13	No	No	0	6	6
68	R:R:M233	R:R:V194	3.04	No	No	0	6	7
69	R:R:I196	R:R:V229	4.61	No	No	0	5	7
70	R:R:K197	R:R:Y220	3.58	No	Yes	0	6	3
71	R:R:D198	R:R:L201	4.07	No	No	0	7	7
72	R:R:A200	R:R:Y220	6.67	No	Yes	0	4	3
73	R:R:D222	R:R:S219	7.36	No	No	0	6	5
74	R:R:S223	R:R:Y220	3.82	No	Yes	0	4	3
75	R:R:C226	R:R:Y220	16.13	No	Yes	0	9	3
76	R:R:V229	R:R:Y220	3.79	No	Yes	0	7	3
77	R:R:C296	R:R:Q221	9.16	No	No	0	9	4
78	R:R:C226	R:R:C296	7.28	No	No	0	9	9
79	R:R:D293	R:R:R227	19.06	No	No	2	7	8
80	R:R:R227	R:R:W297	12	No	No	2	8	8
81	R:R:F230	R:R:Q234	7.03	No	No	2	5	7
82	R:R:F230	R:R:W284	8.02	No	Yes	2	5	8
83	R:R:C236	R:R:L232	3.17	No	No	0	5	5
84	R:R:Q234	R:R:W284	6.57	No	Yes	2	7	8
85	R:R:I309	R:R:Q234	6.86	No	No	2	7	7
86	R:R:W274	R:R:Y235	8.68	Yes	No	0	9	9
87	R:R:V281	R:R:Y235	5.05	No	No	0	6	9
88	R:R:A238	R:R:P277	3.74	No	No	0	6	9
89	R:R:A238	R:R:F280	4.16	No	Yes	0	6	5
90	R:R:A239	R:R:W274	3.89	No	Yes	0	8	9
91	R:R:I313	R:R:Y241	8.46	No	No	0	7	8
92	R:R:I272	R:R:Y242	4.84	No	Yes	9	6	6
93	R:R:V276	R:R:Y242	5.05	No	Yes	9	3	6
94	R:R:P277	R:R:Y242	5.56	No	Yes	0	9	6
95	R:R:F280	R:R:Y242	5.16	Yes	Yes	0	5	6
96	R:R:A316	R:R:Y242	5.34	No	Yes	0	7	6
97	R:R:V246	R:R:W243	3.68	No	Yes	0	8	9
98	R:R:V270	R:R:W243	6.13	No	Yes	0	5	9
99	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
100	R:R:W243	R:R:W274	18.74	Yes	Yes	8	9	9
101	R:R:L244	R:R:N320	5.49	No	No	0	9	9
102	R:R:L245	R:R:V319	4.47	No	No	0	8	6
103	R:R:L245	R:R:N320	10.98	No	No	0	8	9
104	R:R:V246	R:R:Y269	10.09	No	No	0	8	7
105	R:R:E247	R:R:Y402	14.59	No	Yes	1	9	8
106	R:R:V249	R:R:Y269	3.79	No	No	0	6	7
107	R:R:L254	R:R:Y250	3.52	No	Yes	0	8	8
108	R:R:L251	R:R:L349	6.92	No	No	0	9	9
109	R:R:A350	R:R:L251	4.73	No	No	0	8	9
110	R:R:L251	R:R:T353	4.42	No	Yes	0	9	9
111	R:R:L255	R:R:V327	4.47	No	No	0	8	9
112	R:R:I330	R:R:L255	4.28	No	No	0	9	8
113	R:R:E262	R:R:W264	10.9	No	No	10	6	5
114	R:R:E262	R:R:I265	4.1	No	No	10	6	5
115	R:R:Q263	R:R:R267	8.18	No	No	0	5	4
116	R:R:I265	R:R:W264	14.09	No	No	10	5	5
117	R:R:I265	R:R:Y269	4.84	No	No	0	5	7
118	R:R:F266	R:R:V270	7.87	No	No	0	6	5
119	R:R:I272	R:R:V276	7.68	No	No	9	6	3
120	R:R:F280	R:R:I309	5.02	Yes	No	0	5	7
121	R:R:F280	R:R:P312	17.34	Yes	No	0	5	8
122	R:R:P283	R:R:V282	5.3	No	No	0	5	3
123	R:R:K288	R:R:W284	11.6	Yes	Yes	2	8	8
124	R:R:I308	R:R:W284	4.7	No	Yes	0	8	8
125	R:R:I309	R:R:W284	10.57	No	Yes	2	7	8
126	R:R:V287	R:R:Y305	12.62	No	Yes	0	4	4
127	R:R:E292	R:R:K288	10.8	Yes	Yes	2	6	8
128	R:R:E294	R:R:K288	4.05	No	Yes	2	4	8
129	R:R:K288	R:R:W297	17.4	Yes	No	2	8	8
130	R:R:K288	R:R:N300	6.99	Yes	No	0	8	6
131	R:R:D293	R:R:Y289	3.45	No	No	0	7	3
132	R:R:L290	R:R:Y291	9.38	No	No	0	3	3
133	R:R:Y291	R:R:Y305	4.96	No	Yes	0	3	4
134	R:R:E292	R:R:E294	3.81	Yes	No	2	6	4
135	R:R:E292	R:R:N302	11.83	Yes	No	0	6	5
136	R:R:E292	R:R:Y305	12.35	Yes	Yes	0	6	4
137	R:R:D293	R:R:W297	15.63	No	No	2	7	8
138	R:R:E294	R:R:R299	4.65	No	No	0	4	4
139	R:R:N300	R:R:W306	7.91	No	No	0	6	6
140	R:R:M303	R:R:N302	4.21	No	No	0	5	5
141	R:R:M303	R:R:Y305	7.18	No	Yes	0	5	4
142	R:R:L307	R:R:N304	4.12	No	No	0	7	3
143	R:R:R310	R:R:W306	14.99	No	No	0	6	6
144	R:R:L307	R:R:L311	4.15	No	No	0	7	4
145	R:R:E364	R:R:R310	6.98	No	No	0	8	6
146	R:R:L311	R:R:P312	3.28	No	No	0	4	8
147	R:R:E364	R:R:I313	5.47	No	No	0	8	7
148	R:R:C317	R:R:C361	7.28	No	No	0	7	9
149	R:R:C317	R:R:E364	3.04	No	No	0	7	8
150	R:R:C361	R:R:N320	4.72	No	No	0	9	9
151	R:R:F321	R:R:F324	5.36	Yes	Yes	6	6	9
152	R:R:F321	R:R:I357	5.02	Yes	Yes	6	6	8
153	R:R:F321	R:R:P358	8.67	Yes	No	6	6	9
154	R:R:C361	R:R:F321	4.19	No	Yes	0	9	6
155	R:R:F324	R:R:I328	6.28	Yes	No	0	9	7
156	R:R:F324	R:R:L354	10.96	Yes	No	0	9	8
157	R:R:F324	R:R:I357	6.28	Yes	Yes	6	9	8
158	R:R:F324	R:R:P358	10.11	Yes	No	6	9	9
159	R:R:C329	R:R:R326	5.57	No	No	0	7	8
160	R:R:L354	R:R:V327	4.47	No	No	0	8	9
161	R:R:L335	R:R:V331	4.47	No	No	0	8	8
162	R:R:M340	R:R:V331	4.56	No	No	0	5	8
163	R:R:S333	R:R:V332	3.23	No	No	0	7	6
164	R:R:K334	R:R:L339	4.23	No	No	0	9	7
165	R:R:F347	R:R:L335	6.09	Yes	No	0	7	8
166	R:R:A337	R:R:L339	4.73	No	No	0	7	7
167	R:R:D344	R:R:M340	5.54	No	No	0	7	5
168	R:R:F347	R:R:M340	4.98	Yes	No	0	7	5
169	R:R:F347	R:R:K342	18.61	Yes	No	3	7	5
170	R:R:K342	W:W:?1	3.8	No	Yes	3	5	0
171	R:R:I345	R:R:R348	5.01	No	Yes	3	5	8
172	R:R:E408	R:R:I345	4.1	No	No	3	9	5
173	R:R:F347	R:R:K351	6.2	Yes	No	3	7	8
174	R:R:F347	W:W:?1	11.5	Yes	Yes	3	7	0
175	R:R:N407	R:R:R348	12.05	No	Yes	0	6	8
176	R:R:E408	R:R:R348	10.47	No	Yes	3	9	8
177	R:R:R348	W:W:?1	11.47	Yes	Yes	3	8	0
178	R:R:L349	R:R:Y402	3.52	No	Yes	0	9	8
179	R:R:A350	R:R:L354	3.15	No	No	0	8	8
180	R:R:K351	W:W:?1	35.19	No	Yes	3	8	0
181	R:R:L401	R:R:S352	7.51	Yes	No	0	8	9
182	R:R:S352	R:R:Y402	6.36	No	Yes	0	9	8
183	R:R:S352	W:W:?1	4.05	No	Yes	0	9	0
184	R:R:I357	R:R:T353	3.04	Yes	Yes	0	8	9
185	R:R:T353	R:R:Y402	8.74	Yes	Yes	0	9	8
186	R:R:L401	R:R:T355	4.42	Yes	No	0	8	8
187	R:R:T355	W:W:?1	3.98	No	Yes	0	8	0
188	R:R:L356	R:R:L401	4.15	No	Yes	0	9	8
189	R:R:L356	R:R:Y402	5.86	No	Yes	0	9	8
190	R:R:I357	R:R:P358	5.08	Yes	No	6	8	9
191	R:R:L359	R:R:L360	4.15	No	No	0	9	9
192	R:R:L359	R:R:M397	5.65	No	No	0	9	5
193	R:R:L360	R:R:Q394	13.31	No	Yes	0	9	9
194	R:R:I366	R:R:T362	4.56	No	No	0	6	7
195	R:R:F367	R:R:H363	14.71	No	No	0	7	8
196	R:R:E387	R:R:H363	6.15	No	No	0	8	8
197	R:R:F367	R:R:I366	15.07	No	No	0	7	6
198	R:R:F381	R:R:F385	5.36	No	No	0	4	6
199	R:R:E387	R:R:K383	18.9	No	No	0	8	7
200	R:R:Q394	R:R:T391	7.09	Yes	No	0	9	6
201	R:R:F393	R:R:S392	3.96	No	Yes	4	7	9
202	R:R:F393	R:R:L396	3.65	No	No	0	7	7
203	R:R:G395	R:R:V398	3.68	No	No	7	9	9
204	R:R:I400	R:R:L396	4.28	No	No	0	6	7
205	R:R:F404	R:R:I400	7.54	No	No	0	8	6
206	R:R:V405	W:W:?1	8.04	No	Yes	0	6	0
207	R:R:E408	R:R:N406	13.15	No	No	0	9	9
208	R:R:N406	R:R:V409	10.35	No	No	0	9	9
209	R:R:N406	W:W:?1	3.7	No	Yes	0	9	0
210	R:R:E412	R:R:K415	8.1	Yes	No	1	8	7
211	R:R:R414	R:R:W417	8	No	No	0	6	5
212	R:R:K415	R:R:R419	6.19	No	No	0	7	7
213	R:R:E418	R:R:R421	4.65	No	No	0	4	4
214	R:R:L422	R:R:R421	7.29	No	No	0	4	4
215	R:R:G295	R:R:R227	3	No	No	0	4	8
216	R:R:L268	R:R:S271	3	No	No	0	2	3
217	R:R:K383	R:R:T386	3	No	No	0	7	4
218	R:R:L231	R:R:V281	2.98	No	No	0	5	6
219	R:R:L278	R:R:V282	2.98	No	No	0	3	3
220	R:R:I161	R:R:I165	2.94	No	Yes	0	4	8
221	R:R:I330	R:R:K334	2.91	No	No	0	9	9
222	R:R:I318	R:R:L314	2.85	No	No	0	4	4
223	R:R:I318	R:R:L322	2.85	No	No	0	4	5
224	R:R:I400	R:R:L401	2.85	No	Yes	0	6	8
225	R:R:G285	R:R:W284	2.81	No	Yes	0	5	8
226	R:R:L154	R:R:L396	2.77	No	No	0	5	7
227	R:R:A191	R:R:F156	2.77	No	Yes	5	7	7
228	R:R:A158	R:R:F404	2.77	No	No	0	7	8
229	R:R:A191	R:R:F195	2.77	No	No	5	7	7
230	R:R:L224	R:R:L228	2.77	No	No	0	3	4
231	R:R:F390	R:R:S389	2.64	No	No	0	6	5
232	R:R:F321	R:R:V365	2.62	Yes	No	0	6	6
233	R:R:F367	R:R:V370	2.62	No	No	0	7	5
234	R:R:A185	R:R:W274	2.59	No	Yes	0	3	9
235	R:R:F143	R:R:I147	2.51	No	No	0	4	6
236	R:R:F381	R:R:I382	2.51	No	No	0	4	4
237	R:R:F369	R:R:L307	2.44	No	No	0	4	7
238	R:R:L388	R:R:Y148	2.34	No	Yes	0	7	7
239	R:R:L181	R:R:Y178	2.34	No	No	0	6	6
240	R:R:L224	R:R:Y289	2.34	No	No	0	3	3
241	R:R:L278	R:R:Y235	2.34	No	No	0	3	9
242	R:R:E418	R:R:R414	2.33	No	No	0	4	6
243	R:R:L268	R:R:W264	2.28	No	No	0	2	5
244	R:R:F381	R:R:R380	2.14	No	No	0	4	5
245	R:R:R326	R:R:Y252	2.06	No	No	0	8	8
246	R:R:G275	R:R:P277	2.03	No	No	0	6	9
247	R:R:F413	R:R:W417	2	No	No	0	5	5
248	R:R:G151	R:R:V150	1.84	No	No	0	8	5
249	R:R:G248	R:R:T353	1.82	No	Yes	0	8	9
250	R:R:G248	R:R:I323	1.76	No	No	0	8	8
251	R:R:G168	R:R:L167	1.71	No	No	0	1	3
252	R:R:C341	R:R:T343	1.69	No	No	0	4	5
253	R:R:G295	R:R:Q221	1.64	No	No	0	4	4
254	R:R:A346	R:R:I345	1.62	No	No	0	6	5
255	R:R:T149	R:R:V150	1.59	No	No	0	7	5
256	R:R:A368	R:R:L314	1.58	No	No	0	6	4
257	R:R:C341	R:R:D344	1.56	No	No	0	4	7
258	R:R:I147	R:R:S389	1.55	No	No	0	6	5
259	R:R:I188	R:R:S163	1.55	Yes	No	0	7	6
260	R:R:I146	R:R:V150	1.54	No	No	0	4	5
261	R:R:I328	R:R:V332	1.54	No	No	0	7	6
262	R:R:M371	R:R:S301	1.53	No	No	0	7	3
263	R:R:L322	R:R:V319	1.49	No	No	0	5	6
264	R:R:Q221	R:R:S219	1.44	No	No	0	4	5
265	R:R:I147	R:R:L144	1.43	No	No	0	6	6
266	R:R:I286	R:R:L290	1.43	No	No	0	4	3
267	R:R:Q410	R:R:V405	1.43	No	No	0	7	6
268	R:R:Q410	R:R:V409	1.43	No	No	0	7	9
269	R:R:F156	R:R:S157	1.32	Yes	No	0	7	3
270	R:R:F169	R:R:S416	1.32	Yes	No	0	7	5
271	R:R:F315	R:R:V319	1.31	No	No	0	4	6
272	R:R:F324	R:R:V325	1.31	Yes	No	0	9	5
273	R:R:F321	R:R:T362	1.3	Yes	No	0	6	7
274	R:R:F385	R:R:T386	1.3	No	No	0	6	4
275	R:R:V327	R:R:Y252	1.26	No	No	0	9	8
276	R:R:T253	R:R:Y252	1.25	No	No	0	7	8
277	R:R:L384	R:R:R380	1.21	No	No	0	5	5
278	R:R:M371	R:R:W306	1.16	No	No	0	7	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y148	8.4	4	4	7
2	R:R:Y152	9.7275	4	4	7
3	R:R:F156	3.92833	6	5	7
4	R:R:I165	5.1025	4	1	8
5	R:R:F169	4.518	5	1	7
6	R:R:L172	4.36	4	1	9
7	R:R:R176	6.2425	4	1	9
8	R:R:N177	6.658	5	1	9
9	R:R:H180	11.09	4	1	9
10	R:R:F187	7.458	5	7	8
11	R:R:I188	3.525	4	5	7
12	R:R:R190	6.4975	4	0	8
13	R:R:Y220	6.798	5	0	3
14	R:R:Y242	5.19	5	9	6
15	R:R:W243	10.5267	6	8	9
16	R:R:Y250	4.6675	4	0	8
17	R:R:W274	8.136	5	8	9
18	R:R:F280	7.92	4	0	5
19	R:R:W284	7.37833	6	2	8
20	R:R:K288	10.168	5	2	8
21	R:R:E292	9.6975	4	2	6
22	R:R:Y305	9.2775	4	0	4
23	R:R:F321	4.52667	6	6	6
24	R:R:F324	6.71667	6	6	9
25	R:R:F347	9.476	5	3	7
26	R:R:R348	9.75	4	3	8
27	R:R:T353	4.505	4	0	9
28	R:R:I357	4.855	4	6	8
29	R:R:S392	4.145	4	4	9
30	R:R:Q394	7.7325	4	0	9
31	R:R:L401	4.7325	4	0	8
32	R:R:Y402	10.685	6	1	8
33	R:R:E412	8.1375	4	1	8
34	W:W:?1	10.2163	8	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F385	R:R:T386	12.3216	1.3	No	No	0	6	4
2	R:R:K383	R:R:T386	13.5175	3	No	No	0	7	4
3	R:R:E387	R:R:K383	14.7052	18.9	No	No	0	8	7
4	R:R:E387	R:R:H363	15.7856	6.15	No	No	0	8	8
5	R:R:F367	R:R:H363	16.9608	14.71	No	No	0	7	8
6	R:R:F367	R:R:I366	19.2784	15.07	No	No	0	7	6
7	R:R:I366	R:R:T362	20.4247	4.56	No	No	0	6	7
8	R:R:F321	R:R:T362	21.5629	1.3	Yes	No	0	6	7
9	R:R:F321	R:R:I357	74.7753	5.02	Yes	Yes	6	6	8
10	R:R:I357	R:R:T353	89.266	3.04	Yes	Yes	0	8	9
11	R:R:T353	R:R:Y402	100	8.74	Yes	Yes	0	9	8
12	R:R:S352	R:R:Y402	59.9835	6.36	No	Yes	0	9	8
13	R:R:L401	R:R:S352	50.7175	7.51	Yes	No	0	8	9
14	R:R:I400	R:R:L401	97.9918	2.85	No	Yes	0	6	8
15	R:R:I400	R:R:L396	92.3876	4.28	No	No	0	6	7
16	R:R:F393	R:R:L396	88.6103	3.65	No	No	0	7	7
17	R:R:F393	R:R:G151	14.3546	9.03	No	No	4	7	8
18	R:R:G151	R:R:V150	13.1588	1.84	No	No	0	8	5
19	R:R:L356	R:R:Y402	43.7443	5.86	No	Yes	0	9	8
20	R:R:L356	R:R:L401	43.1918	4.15	No	Yes	0	9	8
21	R:R:F393	R:R:S392	72.3505	3.96	No	Yes	4	7	9
22	R:R:S392	R:R:Y148	16.6928	5.09	Yes	Yes	4	9	7
23	R:R:S392	R:R:Y152	54.6887	3.82	Yes	Yes	4	9	7
24	R:R:V194	R:R:Y148	12.5196	6.31	No	Yes	4	7	7
25	R:R:V194	R:R:Y152	12.9567	10.09	No	Yes	4	7	7
26	R:R:R190	R:R:Y152	40.8165	5.14	Yes	Yes	0	8	7
27	R:R:N240	R:R:R190	15.134	9.64	No	Yes	0	9	8
28	R:R:F187	R:R:N240	10.8619	19.33	Yes	No	0	8	9
29	R:R:Q394	R:R:R190	21.6041	4.67	Yes	Yes	0	9	8
30	R:R:F187	R:R:Q394	10.9237	5.86	Yes	Yes	0	8	9
31	R:R:I188	R:R:L159	11.699	5.71	Yes	No	0	7	9
32	R:R:F184	R:R:L159	14.5773	4.87	No	No	0	8	9
33	R:R:F184	R:R:L166	15.967	4.87	No	No	0	8	8
34	R:R:L166	R:R:N177	25.7278	10.98	No	Yes	0	8	9
35	R:R:H180	R:R:N177	41.9505	3.83	Yes	Yes	1	9	9
36	R:R:H180	R:R:Y402	44.3258	25.04	Yes	Yes	1	9	8
37	R:R:F169	R:R:L172	21.1835	4.87	Yes	Yes	1	7	9
38	R:R:L172	R:R:N177	24.4495	4.12	Yes	Yes	1	9	9
39	R:R:F169	R:R:F413	10.7299	3.22	Yes	No	1	7	5
40	R:R:L172	R:R:V409	11.3608	4.47	Yes	No	0	9	9
41	R:R:S352	W:W:?1	24.1649	4.05	No	Yes	0	9	0
42	R:R:N406	W:W:?1	12.2722	3.7	No	Yes	0	9	0
43	R:R:N406	R:R:V409	10.9732	10.35	No	No	0	9	9
44	R:R:E247	R:R:Y402	29.0062	14.59	No	Yes	1	9	8
45	R:R:E247	R:R:I179	31.7608	5.47	No	No	0	9	8
46	R:R:I179	R:R:W243	31.2825	4.7	No	Yes	0	8	9
47	R:R:W243	R:R:W274	13.1794	18.74	Yes	Yes	8	9	9
48	R:R:L232	R:R:S193	12.9691	4.5	No	No	0	5	6
49	R:R:M233	R:R:S193	17.2825	6.13	No	No	0	6	6
50	R:R:M233	R:R:V194	21.5835	3.04	No	No	0	6	7
51	R:R:C361	R:R:F321	69.0845	4.19	No	Yes	0	9	6
52	R:R:C317	R:R:C361	61.6206	7.28	No	No	0	7	9
53	R:R:C317	R:R:E364	60.8289	3.04	No	No	0	7	8
54	R:R:E364	R:R:R310	58.4041	6.98	No	No	0	8	6
55	R:R:R310	R:R:W306	57.5794	14.99	No	No	0	6	6
56	R:R:N300	R:R:W306	55.0557	7.91	No	No	0	6	6
57	R:R:K288	R:R:N300	54.1856	6.99	Yes	No	0	8	6
58	R:R:K288	R:R:W297	21.3938	17.4	Yes	No	2	8	8
59	R:R:R227	R:R:W297	15.4969	12	No	No	2	8	8
60	R:R:G295	R:R:R227	14.532	3	No	No	0	4	8
61	R:R:G295	R:R:Q221	13.3443	1.64	No	No	0	4	4
62	R:R:K288	R:R:W284	24.9031	11.6	Yes	Yes	2	8	8
63	R:R:I309	R:R:W284	19.3691	10.57	No	Yes	2	7	8
64	R:R:F280	R:R:I309	18.334	5.02	Yes	No	0	5	7
65	R:R:V246	R:R:W243	11.8722	3.68	No	Yes	0	8	9
66	R:R:C361	R:R:N320	11.2041	4.72	No	No	0	9	9
67	R:R:V246	R:R:Y269	10.4165	10.09	No	No	0	8	7
68	R:R:L251	R:R:T353	11.3814	4.42	No	Yes	0	9	9
69	R:R:L251	R:R:L349	10.9897	6.92	No	No	0	9	9
70	R:R:L349	R:R:Y402	11.6701	3.52	No	Yes	0	9	8
71	R:R:A350	R:R:L354	18.4907	3.15	No	No	0	8	8
72	R:R:F324	R:R:L354	13.8639	10.96	Yes	No	0	9	8
73	R:R:L354	R:R:V327	28.6557	4.47	No	No	0	8	9
74	R:R:L255	R:R:V327	14.4289	4.47	No	No	0	8	9
75	R:R:I330	R:R:L255	11.5588	4.28	No	No	0	9	8
76	R:R:E292	R:R:K288	11.1299	10.8	Yes	Yes	2	6	8
77	R:R:V327	R:R:Y252	11.5588	1.26	No	No	0	9	8
78	R:R:F347	W:W:?1	11.1959	11.5	Yes	Yes	3	7	0
79	R:R:A350	R:R:L251	19.6866	4.73	No	No	0	8	9
80	R:R:F324	R:R:I357	13.2577	6.28	Yes	Yes	6	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F347	R:R:L335	6.09	3	Yes	No	7	8	1	2
R:R:F347	R:R:M340	4.98	3	Yes	No	7	5	1	2
R:R:F347	R:R:K342	18.61	3	Yes	No	7	5	1	1
R:R:K342	W:W:?1	3.8	3	No	Yes	5	0	1	0
R:R:I345	R:R:R348	5.01	3	No	Yes	5	8	2	1
R:R:E408	R:R:I345	4.1	3	No	No	9	5	2	2
R:R:F347	R:R:K351	6.2	3	Yes	No	7	8	1	1
R:R:F347	W:W:?1	11.5	3	Yes	Yes	7	0	1	0
R:R:N407	R:R:R348	12.05	0	No	Yes	6	8	2	1
R:R:E408	R:R:R348	10.47	3	No	Yes	9	8	2	1
R:R:R348	W:W:?1	11.47	3	Yes	Yes	8	0	1	0
R:R:K351	W:W:?1	35.19	3	No	Yes	8	0	1	0
R:R:L401	R:R:S352	7.51	0	Yes	No	8	9	2	1
R:R:S352	R:R:Y402	6.36	0	No	Yes	9	8	1	2
R:R:S352	W:W:?1	4.05	0	No	Yes	9	0	1	0
R:R:L401	R:R:T355	4.42	0	Yes	No	8	8	2	1
R:R:T355	W:W:?1	3.98	0	No	Yes	8	0	1	0
R:R:V405	W:W:?1	8.04	0	No	Yes	6	0	1	0
R:R:E408	R:R:N406	13.15	3	No	No	9	9	2	1
R:R:N406	R:R:V409	10.35	0	No	No	9	9	1	2
R:R:N406	W:W:?1	3.7	0	No	Yes	9	0	1	0
R:R:Q410	R:R:V405	1.43	0	No	No	7	6	2	1
R:R:Q410	R:R:V409	1.43	0	No	No	7	9	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
77.78	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
70.00	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
63.64	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
58.33	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
53.85	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
50.00	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
29.41	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
27.27	Single	7EB2	rac-BHFF	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
27.27	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
27.27	Consensus	gabab_on	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
27.27	Consensus	gi_class-c	Other Ligand	gi_mglu gi_gaba
25.00	Consensus	gi_gaba	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
23.08	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
21.43	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
20.00	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
20.00	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
20.00	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
18.75	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
15.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
14.29	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
14.29	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
13.33	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
13.33	Consensus	nts1_on_allo	Other Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
13.04	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
12.50	Single	7DUR	PubChem 156022738	7DUR-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
11.11	Single	7E14	PubChem 156022738	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
11.11	Single	7EVM	PubChem 156022738	7EVM-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
11.11	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/&β;1/&γ;2
11.11	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
10.53	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
10.00	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
10.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
10.00	Consensus	ccr9_off_allo	Other Ligand	5LWE-CCR9-Vercirnon
9.09	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
8.70	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
8.33	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
5.56	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
3.45	Single	3VG9	Antibody	3VG9-A_2A-ZM241385-Antibody
3.23	Single	3VGA	Antibody	3VGA-A_2A-ZM241385-Antibody

PDB Summary
PDB	6KK7
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GLP-1
Species	Homo sapiens
Ligand	-
Other Ligand(s)	PubChem 68178630
Protein Partners	-
PDB Resolution	3.1
Date	2019-11-13
D.O.I.	10.1107/S2052252519013496

Net Summary
I_min	3.04
Number of Linked Nodes	244
Number of Links	278
Number of Hubs	34
Number of Links mediated by Hubs	131
Number of Communities	10
Number of Nodes involved in Communities	57
Number of Links involved in Communities	72

Path Summary
Number Of Nodes in MetaPath	81
Number Of Links MetaPath	80
Number of Shortest Paths	50290
Length Of Smallest Path	3
Average Path Length	15.1755
Length of Longest Path	33
Minimum Path Strength	1.255
Average Path Strength	6.42818
Maximum Path Strength	23.33
Minimum Path Correlation	0.7
Average Path Correlation	0.931548
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	49.1009
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.2665
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	97Y
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	97Y
Name	N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Synonyms
Identifier	3-[[4-[(~{R})-(3,3-dimethylcyclobutyl)-[[6-[4-(trifluoromethyl)imidazol-1-yl]pyridin-3-yl]amino]methyl]phenyl]carbonylamino]propanoic acid
Formula	C26 H28 F3 N5 O3
Molecular Weight	515.527
SMILES	CC1(CC(C1)[C@H](c2ccc(cc2)C(=O)NCCC(=O)O)Nc3ccc(nc3)n4cc(nc4)C(F)(F)F)C
PubChem	68178630
Formal Charge	0
Total Atoms	65
Total Chiral Atoms	1
Total Bonds	68
Total Aromatic Bonds	17


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>6KK7_Chain_R S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W S Y Q D S L A C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A C I V N F L I F V R V I C I V V S K L K A N L M C K T D I A F R L A K S T L T L I P L L C T H E V I F A F V M R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/&β;1/&γ;2	4.1	2017-05-24	10.1038/nature22394
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/&β;1/&γ;2	3.3	2018-02-21	10.1038/nature25773
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/&β;1/&γ;2	3	2020-01-08	10.1038/s41586-019-1902-z
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/&β;1/&γ;2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2020-11-18	10.1073/pnas.2014879117
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/&β;1/&γ;2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/&β;1/&γ;2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/&β;1/&γ;2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/&β;1/&γ;2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/&β;1/&γ;2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/&β;1/&γ;2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/&β;1/&γ;2	3	2022-03-02	10.1038/s41467-022-28683-0
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/&β;1/&γ;2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/&β;1/&γ;2	3.09	2022-06-29	10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.46	2023-11-08	10.1073/pnas.2303696120
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.54	2024-03-06	10.1038/s41421-024-00649-0

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