psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:Q12	A:A:R13	8.18	No	No	0	2	4
2	A:A:E16	A:A:R20	12.79	No	No	0	4	3
3	A:A:K17	A:A:R20	7.43	No	No	0	4	3
4	A:A:Q19	B:B:D83	9.14	No	Yes	7	4	8
5	A:A:Q19	B:B:T86	7.09	No	No	7	4	6
6	A:A:Q19	B:B:N88	13.2	No	Yes	7	4	7
7	A:A:R20	B:B:N88	3.62	No	Yes	0	3	7
8	A:A:E27	A:A:N23	10.52	No	No	7	6	7
9	A:A:N23	B:B:N88	12.26	No	Yes	7	7	7
10	A:A:N23	B:B:K89	8.39	No	Yes	7	7	9
11	A:A:E27	A:A:K24	4.05	No	No	0	6	4
12	A:A:I26	B:B:A92	4.87	No	No	0	9	6
13	A:A:E27	B:B:K89	4.05	No	Yes	7	6	9
14	A:A:K32	A:A:Q29	5.42	No	No	0	4	4
15	A:A:D33	A:A:Q29	13.05	No	No	0	5	4
16	A:A:L30	B:B:K78	4.23	No	No	0	5	8
17	A:A:D33	B:B:K78	6.91	No	No	0	5	8
18	A:A:K34	A:A:R38	9.9	No	No	0	4	4
19	A:A:K34	B:B:L55	5.64	No	No	0	4	6
20	A:A:R42	A:A:Y37	21.61	No	No	0	9	4
21	A:A:Y37	B:B:L55	4.69	No	No	22	4	6
22	A:A:Y37	B:B:D76	4.6	No	Yes	22	4	9
23	A:A:F219	A:A:H41	3.39	Yes	No	0	8	6
24	A:A:H41	A:A:T242	10.95	No	No	0	6	8
25	A:A:H41	R:R:F314	9.05	No	Yes	0	6	7
26	A:A:F222	A:A:R42	4.28	Yes	No	0	7	9
27	A:A:F219	A:A:L43	6.09	Yes	No	0	8	7
28	A:A:I245	A:A:L43	5.71	No	No	0	7	7
29	A:A:F238	A:A:L44	14.61	Yes	No	0	9	9
30	A:A:I244	A:A:L44	5.71	No	No	0	8	9
31	A:A:K53	A:A:L45	7.05	Yes	No	15	9	8
32	A:A:L45	A:A:M221	4.24	No	No	0	8	8
33	A:A:D223	A:A:L45	6.79	No	No	15	9	8
34	A:A:G47	A:A:S51	3.71	No	Yes	15	9	9
35	A:A:G47	A:A:K53	5.23	No	Yes	15	9	9
36	A:A:D249	A:A:N50	8.08	No	No	18	8	9
37	A:A:D252	A:A:N50	10.77	Yes	No	18	8	9
38	A:A:N50	A:A:R265	18.08	No	Yes	18	9	9
39	A:A:G52	A:A:S51	3.71	No	Yes	0	9	9
40	A:A:K53	A:A:S51	4.59	Yes	Yes	15	9	9
41	A:A:S51	A:A:V247	6.46	Yes	Yes	15	9	7
42	A:A:D223	A:A:K53	9.68	No	Yes	15	9	9
43	A:A:K53	A:A:V247	3.04	Yes	Yes	15	9	7
44	A:A:I56	A:A:V247	4.61	No	Yes	0	7	7
45	A:A:T210	A:A:V57	4.76	No	No	0	7	7
46	A:A:N371	A:A:Q59	5.28	Yes	No	0	9	9
47	A:A:F212	A:A:M60	7.46	Yes	No	0	9	9
48	A:A:G206	B:B:N119	3.39	No	No	0	8	9
49	A:A:F222	A:A:I207	3.77	Yes	No	17	7	9
50	A:A:I207	A:A:V224	3.07	No	No	0	9	9
51	A:A:I207	B:B:W99	3.52	No	Yes	17	9	9
52	A:A:D223	A:A:F208	5.97	No	No	0	9	5
53	A:A:E209	A:A:H220	12.31	No	No	17	9	7
54	A:A:E209	A:A:F222	3.5	No	Yes	17	9	7
55	A:A:H220	A:A:K211	14.41	No	No	0	7	4
56	A:A:F212	A:A:F219	17.15	Yes	Yes	0	9	8
57	A:A:F212	A:A:M221	3.73	Yes	No	0	9	8
58	A:A:K216	A:A:Q213	5.42	No	No	0	4	3
59	A:A:N218	A:A:Q213	10.56	No	No	0	4	3
60	A:A:R373	A:A:V214	3.92	Yes	No	10	5	6
61	A:A:F376	A:A:V214	10.49	Yes	No	10	8	6
62	A:A:D215	A:A:R373	10.72	No	Yes	10	5	5
63	A:A:D215	A:A:F376	7.17	No	Yes	10	5	8
64	A:A:F219	A:A:V217	5.24	Yes	No	10	8	5
65	A:A:F376	A:A:V217	6.55	Yes	No	10	8	5
66	A:A:V217	R:R:F314	5.24	No	Yes	10	5	7
67	A:A:F219	A:A:F376	3.22	Yes	Yes	10	8	8
68	A:A:C379	A:A:F219	6.98	No	Yes	0	8	8
69	A:A:F222	A:A:H220	16.97	Yes	No	17	7	7
70	A:A:F222	B:B:W99	18.04	Yes	Yes	17	7	9
71	A:A:V224	A:A:W234	13.48	No	Yes	0	9	9
72	A:A:Q227	A:A:W234	6.57	Yes	Yes	0	9	9
73	A:A:Q227	B:B:L117	3.99	Yes	No	0	9	9
74	A:A:Q227	B:B:N119	6.6	Yes	No	0	9	9
75	A:A:Q227	B:B:Y145	6.76	Yes	Yes	0	9	8
76	A:A:E230	A:A:R228	9.3	Yes	No	1	9	9
77	A:A:R228	B:B:T164	5.17	No	No	0	9	6
78	A:A:R228	B:B:D186	8.34	No	Yes	1	9	9
79	A:A:E230	A:A:R232	4.65	Yes	No	0	9	8
80	A:A:E230	B:B:D186	5.2	Yes	Yes	1	9	9
81	A:A:R231	A:A:W234	7	No	Yes	0	9	9
82	A:A:L272	A:A:R231	9.72	No	No	0	8	9
83	A:A:R232	B:B:D228	13.1	No	Yes	0	8	9
84	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
85	A:A:K233	B:B:M188	8.64	Yes	No	1	9	8
86	A:A:K233	B:B:C204	4.85	Yes	Yes	1	9	7
87	A:A:K233	B:B:D228	8.3	Yes	Yes	1	9	9
88	A:A:K233	B:B:N230	4.2	Yes	No	1	9	9
89	A:A:K233	B:B:D246	4.15	Yes	No	1	9	9
90	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
91	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
92	A:A:Q236	A:A:W281	5.48	No	Yes	5	8	5
93	A:A:Q236	B:B:R314	3.5	No	Yes	5	8	8
94	A:A:C237	B:B:Q75	4.58	No	Yes	0	8	9
95	A:A:C237	B:B:M101	4.86	No	Yes	0	8	9
96	A:A:F238	A:A:V241	5.24	Yes	No	0	9	9
97	A:A:F238	B:B:W99	14.03	Yes	Yes	0	9	9
98	A:A:D240	A:A:N239	8.08	No	No	5	6	8
99	A:A:N239	B:B:K57	8.39	No	Yes	5	8	9
100	A:A:N239	B:B:W332	13.56	No	Yes	5	8	9
101	A:A:D240	B:B:K57	6.91	No	Yes	5	6	9
102	A:A:I285	A:A:V241	3.07	No	No	0	7	9
103	A:A:C379	A:A:T242	3.38	No	No	0	8	8
104	A:A:A243	A:A:I288	3.25	No	No	0	8	9
105	A:A:I244	A:A:I285	5.89	No	No	0	8	7
106	A:A:F246	A:A:L272	7.31	No	No	0	9	8
107	A:A:N292	A:A:V247	4.43	No	Yes	0	9	7
108	A:A:F345	A:A:V248	6.55	Yes	No	0	8	7
109	A:A:D249	A:A:D252	7.98	No	Yes	18	8	8
110	A:A:D249	A:A:K293	17.97	No	No	0	8	9
111	A:A:L291	A:A:S250	4.5	No	No	0	8	6
112	A:A:Q294	A:A:S250	4.33	Yes	No	2	6	6
113	A:A:L297	A:A:S250	3	Yes	No	2	8	6
114	A:A:L296	A:A:S251	3	Yes	No	0	6	9
115	A:A:K300	A:A:S251	6.12	Yes	No	0	9	9
116	A:A:D252	A:A:N264	5.39	Yes	No	18	8	9
117	A:A:D252	A:A:R265	13.1	Yes	Yes	18	8	9
118	A:A:L297	A:A:Y253	3.52	Yes	Yes	2	8	8
119	A:A:K300	A:A:Y253	17.91	Yes	Yes	2	9	8
120	A:A:S306	A:A:Y253	6.36	No	Yes	2	7	8
121	A:A:I308	A:A:Y253	12.09	No	Yes	0	7	8
122	A:A:N264	A:A:R265	4.82	No	Yes	18	9	9
123	A:A:N264	A:A:Y311	4.65	No	No	0	9	6
124	A:A:E268	A:A:R265	9.3	No	Yes	0	9	9
125	A:A:F312	A:A:L266	4.87	Yes	No	0	8	8
126	A:A:I341	A:A:L266	4.28	No	No	0	8	8
127	A:A:L270	A:A:Q267	5.32	No	No	0	6	4
128	A:A:N271	A:A:Q267	5.28	No	No	0	5	4
129	A:A:E344	A:A:L270	3.98	Yes	No	0	5	6
130	A:A:F345	A:A:L270	9.74	Yes	No	0	8	6
131	A:A:I276	A:A:L272	4.28	No	No	0	8	8
132	A:A:F273	A:A:W277	5.01	Yes	Yes	2	9	6
133	A:A:F273	A:A:V287	5.24	Yes	No	2	9	6
134	A:A:F273	A:A:F345	5.36	Yes	Yes	0	9	8
135	A:A:F273	A:A:I348	6.28	Yes	No	0	9	4
136	A:A:F273	A:A:S349	3.96	Yes	Yes	2	9	7
137	A:A:C359	A:A:F273	4.19	No	Yes	2	5	9
138	A:A:K274	A:A:N278	5.6	No	No	0	5	8
139	A:A:V287	A:A:W277	3.68	No	Yes	2	6	6
140	A:A:S349	A:A:W277	11.12	Yes	Yes	2	7	6
141	A:A:S352	A:A:W277	3.71	No	Yes	0	5	6
142	A:A:H357	A:A:W277	29.62	No	Yes	2	7	6
143	A:A:N278	A:A:S352	4.47	No	No	0	8	5
144	A:A:N279	A:A:W281	3.39	No	Yes	0	8	5
145	A:A:L282	A:A:N279	10.98	No	No	0	9	8
146	A:A:R280	A:A:W281	22.99	No	Yes	5	5	5
147	A:A:R280	A:A:R283	5.33	No	No	0	5	3
148	A:A:R280	B:B:D290	5.96	No	Yes	5	5	6
149	A:A:W281	B:B:D290	8.93	Yes	Yes	5	5	6
150	A:A:W281	B:B:R314	23.99	Yes	Yes	5	5	8
151	A:A:W281	B:B:W332	4.69	Yes	Yes	5	5	9
152	A:A:R283	A:A:R356	12.79	No	Yes	0	3	2
153	A:A:I382	A:A:S286	6.19	No	No	0	6	8
154	A:A:F290	A:A:I288	3.77	Yes	No	0	9	9
155	A:A:D378	A:A:I288	9.8	No	No	0	7	9
156	A:A:L289	A:A:L291	6.92	Yes	No	0	9	8
157	A:A:F345	A:A:L289	7.31	Yes	Yes	0	8	9
158	A:A:C359	A:A:L289	3.17	No	Yes	0	5	9
159	A:A:L289	A:A:P361	4.93	Yes	No	0	9	5
160	A:A:F290	A:A:H362	6.79	Yes	No	0	9	9
161	A:A:F290	A:A:T364	6.49	Yes	No	23	9	9
162	A:A:F290	A:A:N371	4.83	Yes	Yes	23	9	9
163	A:A:F290	A:A:I375	5.02	Yes	No	0	9	9
164	A:A:F363	A:A:L291	3.65	Yes	No	0	5	8
165	A:A:K293	A:A:N292	8.39	No	No	0	9	9
166	A:A:N292	A:A:T364	4.39	No	No	0	9	9
167	A:A:K293	A:A:L296	4.23	No	Yes	0	9	6
168	A:A:L297	A:A:Q294	5.32	Yes	Yes	2	8	6
169	A:A:K338	A:A:Q294	8.14	Yes	Yes	2	5	6
170	A:A:F363	A:A:Q294	10.54	Yes	Yes	2	5	6
171	A:A:D295	A:A:L296	6.79	No	Yes	0	9	6
172	A:A:K300	A:A:S306	9.18	Yes	No	2	9	7
173	A:A:R333	A:A:V301	3.92	No	No	0	5	7
174	A:A:V301	A:A:V334	4.81	No	No	0	7	4
175	A:A:D331	A:A:L302	4.07	No	No	24	4	2
176	A:A:L302	A:A:R333	4.86	No	No	24	2	5
177	A:A:L302	A:A:V334	4.47	No	No	0	2	4
178	A:A:A303	A:A:K305	4.82	No	No	0	5	3
179	A:A:E309	A:A:K307	6.75	No	No	0	4	6
180	A:A:D310	A:A:K307	9.68	No	No	0	3	6
181	A:A:F312	A:A:I308	3.77	Yes	No	0	8	7
182	A:A:F315	A:A:I308	12.56	Yes	No	0	6	7
183	A:A:E309	A:A:F315	7	No	Yes	0	4	6
184	A:A:E314	A:A:F312	7	Yes	Yes	13	6	8
185	A:A:F312	A:A:F340	6.43	Yes	Yes	13	8	7
186	A:A:E344	A:A:F312	3.5	Yes	Yes	13	5	8
187	A:A:E314	A:A:P313	4.72	Yes	No	0	6	6
188	A:A:E314	A:A:R317	4.65	Yes	No	0	6	2
189	A:A:E314	A:A:F340	5.83	Yes	Yes	13	6	7
190	A:A:E314	A:A:E344	6.34	Yes	Yes	13	6	5
191	A:A:F315	A:A:Y318	3.09	Yes	Yes	13	6	6
192	A:A:F315	A:A:R336	17.1	Yes	No	13	6	5
193	A:A:F315	A:A:F340	18.22	Yes	Yes	13	6	7
194	A:A:P321	A:A:Y318	5.56	Yes	Yes	0	5	6
195	A:A:R336	A:A:Y318	4.12	No	Yes	13	5	6
196	A:A:F340	A:A:Y318	14.44	Yes	Yes	13	7	6
197	A:A:D343	A:A:Y318	11.49	No	Yes	0	3	6
198	A:A:P321	A:A:T320	5.25	Yes	No	0	5	1
199	A:A:R336	A:A:T320	3.88	No	No	0	5	1
200	A:A:D323	A:A:P321	3.22	No	Yes	0	4	5
201	A:A:P321	A:A:Y339	5.56	Yes	Yes	0	5	3
202	A:A:A324	A:A:Y339	8.01	No	Yes	0	3	3
203	A:A:E330	A:A:P326	6.29	Yes	No	2	3	1
204	A:A:P326	A:A:T335	6.99	No	No	2	1	4
205	A:A:E327	A:A:E330	11.42	No	Yes	0	4	3
206	A:A:E330	A:A:T335	7.06	Yes	No	2	3	4
207	A:A:E330	A:A:K338	5.4	Yes	Yes	2	3	5
208	A:A:D331	A:A:P332	9.66	No	No	0	4	1
209	A:A:D331	A:A:R333	11.91	No	No	24	4	5
210	A:A:K338	A:A:Y339	4.78	Yes	Yes	2	5	3
211	A:A:F363	A:A:K338	17.37	Yes	Yes	2	5	5
212	A:A:R342	A:A:Y339	7.2	Yes	Yes	2	4	3
213	A:A:F363	A:A:Y339	8.25	Yes	Yes	2	5	3
214	A:A:E344	A:A:F340	13.99	Yes	Yes	13	5	7
215	A:A:D343	A:A:R342	4.76	No	Yes	0	3	4
216	A:A:L346	A:A:R342	4.86	No	Yes	2	4	4
217	A:A:P361	A:A:R342	7.21	No	Yes	2	5	4
218	A:A:F363	A:A:R342	8.55	Yes	Yes	2	5	4
219	A:A:D343	R:R:R396	9.53	No	No	0	3	5
220	A:A:E344	A:A:R347	6.98	Yes	No	0	5	4
221	A:A:L346	A:A:S349	3	No	Yes	2	4	7
222	A:A:L346	A:A:P361	3.28	No	No	2	4	5
223	A:A:C359	A:A:S349	5.16	No	Yes	2	5	7
224	A:A:T350	R:R:N393	5.85	No	No	0	4	7
225	A:A:G353	A:A:R356	4.5	No	Yes	2	4	2
226	A:A:G353	A:A:H357	3.18	No	No	2	4	7
227	A:A:G355	A:A:Y358	5.79	No	Yes	0	2	4
228	A:A:H357	A:A:R356	9.03	No	Yes	2	7	2
229	A:A:R385	A:A:Y358	8.23	Yes	Yes	11	5	4
230	A:A:R389	A:A:Y358	5.14	No	Yes	11	4	4
231	A:A:Y358	R:R:T392	4.99	Yes	Yes	11	4	7
232	A:A:Y358	R:R:N393	9.3	Yes	No	11	4	7
233	A:A:D378	A:A:Y360	17.24	No	No	0	7	8
234	A:A:D381	A:A:Y360	13.79	No	No	0	8	8
235	A:A:I382	A:A:Y360	6.04	No	No	0	6	8
236	A:A:H362	A:A:R374	16.93	No	No	0	9	4
237	A:A:D378	A:A:H362	8.82	No	No	0	7	9
238	A:A:N371	A:A:T364	7.31	Yes	No	23	9	9
239	A:A:D368	A:A:E370	5.2	No	No	0	9	4
240	A:A:D368	A:A:N371	13.46	No	Yes	0	9	9
241	A:A:D368	A:A:R374	7.15	No	No	0	9	4
242	A:A:E370	A:A:T369	4.23	No	No	0	4	9
243	A:A:F376	A:A:R373	3.21	Yes	Yes	10	8	5
244	A:A:N377	A:A:R373	8.44	No	Yes	10	4	5
245	A:A:F376	A:A:N377	3.62	Yes	No	10	8	4
246	A:A:F376	R:R:F314	7.5	Yes	Yes	10	8	7
247	A:A:Q384	A:A:R380	8.18	No	No	0	6	7
248	A:A:R380	R:R:F314	7.48	No	Yes	0	7	7
249	A:A:D381	A:A:R385	15.48	No	Yes	11	8	5
250	A:A:D381	R:R:K388	6.91	No	Yes	11	8	9
251	A:A:H387	A:A:I383	3.98	No	No	0	8	8
252	A:A:Q384	R:R:I310	4.12	No	No	0	6	8
253	A:A:Q384	R:R:K388	9.49	No	Yes	0	6	9
254	A:A:R385	A:A:R389	4.26	Yes	No	11	5	4
255	A:A:L394	A:A:R385	3.64	No	Yes	11	8	5
256	A:A:R385	R:R:K388	6.19	Yes	Yes	11	5	9
257	A:A:R385	R:R:T392	6.47	Yes	Yes	11	5	7
258	A:A:H387	A:A:M386	7.88	No	No	0	8	3
259	A:A:M386	A:A:Q390	8.16	No	No	0	3	4
260	A:A:H387	R:R:L309	11.57	No	No	0	8	8
261	A:A:L388	A:A:L394	4.15	No	No	0	8	8
262	A:A:L393	A:A:Y391	5.86	No	Yes	0	8	4
263	A:A:Y391	R:R:R219	7.2	Yes	Yes	6	4	9
264	A:A:Y391	R:R:L306	9.38	Yes	No	0	4	9
265	A:A:Y391	W:W:?1	4.92	Yes	Yes	6	4	0
266	A:A:E392	R:R:G464	4.91	No	No	0	6	7
267	A:A:E392	W:W:?1	5.56	No	Yes	0	6	0
268	A:A:L393	R:R:S409	4.5	No	No	0	8	9
269	A:A:L393	R:R:L413	5.54	No	No	0	8	9
270	A:A:L394	R:R:K388	4.23	No	Yes	11	8	9
271	B:B:E3	B:B:L7	5.3	No	Yes	0	5	8
272	B:B:D5	B:B:Q9	6.53	No	No	0	1	3
273	B:B:E10	B:B:Q6	10.19	No	No	0	8	1
274	B:B:E10	B:B:L7	3.98	No	Yes	0	8	8
275	B:B:L14	B:B:Q17	6.65	No	No	0	8	4
276	B:B:I18	B:B:R22	7.52	No	Yes	0	7	6
277	B:B:I18	G:G:A23	3.25	No	No	0	7	8
278	B:B:D258	B:B:R22	9.53	Yes	Yes	3	7	6
279	B:B:Q259	B:B:R22	4.67	Yes	Yes	0	6	6
280	B:B:R22	G:G:R27	6.4	Yes	Yes	3	6	8
281	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
282	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
283	B:B:A28	B:B:D27	3.09	No	No	0	4	8
284	B:B:D27	G:G:K29	6.91	No	No	0	8	4
285	B:B:D27	G:G:S31	8.83	No	No	0	8	9
286	B:B:A28	B:B:Q32	3.03	No	No	0	4	1
287	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
288	B:B:L30	B:B:T34	4.42	No	Yes	0	5	5
289	B:B:L30	B:B:M262	9.9	No	Yes	0	5	4
290	B:B:M262	B:B:S31	3.07	Yes	No	0	4	1
291	B:B:I33	G:G:A34	3.25	No	No	0	3	6
292	B:B:I37	B:B:T34	4.56	Yes	Yes	16	2	5
293	B:B:L300	B:B:T34	7.37	No	Yes	0	6	5
294	B:B:T34	G:G:M38	4.52	Yes	No	16	5	4
295	B:B:N35	B:B:N36	9.54	No	No	0	1	1
296	B:B:I37	B:B:R283	5.01	Yes	Yes	16	2	9
297	B:B:I37	G:G:M38	4.37	Yes	No	16	2	4
298	B:B:R283	B:B:V40	7.85	Yes	No	16	9	3
299	B:B:D298	B:B:V40	10.22	No	No	16	9	3
300	B:B:A305	B:B:I43	3.25	No	No	0	4	3
301	B:B:L308	B:B:M45	4.24	No	No	0	7	4
302	B:B:M45	G:G:L50	5.65	No	No	0	4	9
303	B:B:R46	B:B:R48	7.46	No	Yes	0	5	7
304	B:B:K337	B:B:T47	6.01	Yes	No	9	6	3
305	B:B:T47	B:B:W339	8.49	No	Yes	9	3	9
306	B:B:N340	B:B:R48	6.03	No	Yes	0	9	7
307	B:B:R48	G:G:F61	6.41	Yes	Yes	0	7	8
308	B:B:R48	G:G:R62	12.79	Yes	No	0	7	7
309	B:B:R49	G:G:F61	8.55	No	Yes	0	7	8
310	B:B:R52	B:B:T50	9.06	No	No	0	7	3
311	B:B:K337	B:B:T50	7.51	Yes	No	0	6	3
312	B:B:L51	B:B:W82	19.36	No	Yes	0	9	9
313	B:B:L51	B:B:T87	4.42	No	No	0	9	5
314	B:B:L336	B:B:L51	6.92	No	No	0	7	9
315	B:B:F335	B:B:R52	11.76	No	No	0	4	7
316	B:B:H54	B:B:I58	11.93	Yes	No	0	9	9
317	B:B:H54	B:B:S72	8.37	Yes	No	7	9	9
318	B:B:H54	B:B:S74	11.16	Yes	No	0	9	9
319	B:B:H54	B:B:I80	13.26	Yes	No	7	9	8
320	B:B:H54	B:B:W82	6.35	Yes	Yes	7	9	9
321	B:B:D76	B:B:L55	6.79	Yes	No	22	9	6
322	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
323	B:B:K57	B:B:Q75	13.56	Yes	Yes	0	9	9
324	B:B:K57	B:B:W332	17.4	Yes	Yes	5	9	9
325	B:B:Q75	B:B:Y59	3.38	Yes	No	0	9	8
326	B:B:M101	B:B:Y59	10.78	Yes	No	0	9	8
327	B:B:M61	B:B:W63	5.82	No	Yes	0	6	7
328	B:B:C317	B:B:M61	4.86	No	No	0	7	6
329	B:B:G319	B:B:M61	3.49	No	No	0	5	6
330	B:B:H62	B:B:R150	18.05	No	No	0	6	6
331	B:B:L70	B:B:W63	15.94	No	Yes	8	5	7
332	B:B:S84	B:B:W63	7.41	No	Yes	8	5	7
333	B:B:T321	B:B:W63	9.7	No	Yes	8	7	7
334	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
335	B:B:G64	B:B:Y105	4.35	No	No	0	5	6
336	B:B:D66	B:B:R68	3.57	No	No	0	8	5
337	B:B:D66	B:B:L69	8.14	No	No	0	8	5
338	B:B:S67	B:B:T321	9.59	No	No	8	5	7
339	B:B:D323	B:B:S67	10.31	No	No	8	7	5
340	B:B:D83	B:B:R68	17.87	Yes	No	0	8	5
341	B:B:R68	B:B:Y85	25.72	No	No	0	5	4
342	B:B:D83	B:B:L69	4.07	Yes	No	0	8	5
343	B:B:L70	B:B:S84	4.5	No	No	8	5	5
344	B:B:L79	B:B:V71	4.47	Yes	Yes	0	7	8
345	B:B:I81	B:B:V71	3.07	No	Yes	0	7	8
346	B:B:C103	B:B:V71	5.12	No	Yes	0	8	8
347	B:B:V112	B:B:V71	3.21	No	Yes	0	8	8
348	B:B:S72	B:B:W82	7.41	No	Yes	7	9	9
349	B:B:L336	B:B:S72	3	No	No	0	7	9
350	B:B:A73	B:B:V100	3.39	No	No	0	9	9
351	B:B:A73	B:B:C103	3.61	No	No	0	9	8
352	B:B:D76	B:B:S74	8.83	Yes	No	0	9	9
353	B:B:Q75	B:B:W99	6.57	Yes	Yes	0	9	9
354	B:B:D76	B:B:K78	6.91	Yes	No	0	9	8
355	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
356	B:B:I93	B:B:L79	5.71	Yes	Yes	0	7	7
357	B:B:L79	B:B:L95	5.54	Yes	Yes	12	7	8
358	B:B:C114	B:B:L79	6.35	Yes	Yes	12	8	7
359	B:B:I80	B:B:W82	14.09	No	Yes	7	8	9
360	B:B:I80	B:B:K89	5.82	No	Yes	7	8	9
361	B:B:I81	B:B:V90	3.07	No	No	25	7	5
362	B:B:H91	B:B:I81	3.98	No	No	25	5	7
363	B:B:K89	B:B:W82	12.76	Yes	Yes	7	9	9
364	B:B:D83	B:B:T86	7.23	Yes	No	7	8	6
365	B:B:S84	G:G:F61	5.28	No	Yes	8	5	8
366	B:B:Y85	G:G:P60	11.13	No	Yes	8	4	9
367	B:B:Y85	G:G:F61	5.16	No	Yes	8	4	8
368	B:B:N88	B:B:T86	7.31	Yes	No	7	7	6
369	B:B:H91	B:B:V90	5.54	No	No	25	5	5
370	B:B:H91	B:B:V133	8.3	No	No	0	5	4
371	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
372	B:B:I93	B:B:Y124	8.46	Yes	Yes	0	7	6
373	B:B:I93	B:B:V133	6.14	Yes	No	0	7	4
374	B:B:L95	B:B:V100	4.47	Yes	No	12	8	9
375	B:B:C114	B:B:L95	4.76	Yes	Yes	12	8	8
376	B:B:L95	B:B:Y124	5.86	Yes	Yes	12	8	6
377	B:B:E138	B:B:R96	13.96	Yes	No	0	6	6
378	B:B:D118	B:B:S97	7.36	No	No	0	9	8
379	B:B:S98	B:B:W99	7.41	No	Yes	0	8	9
380	B:B:L117	B:B:W99	4.56	No	Yes	0	9	9
381	B:B:C114	B:B:V100	3.42	Yes	No	12	8	9
382	B:B:G116	B:B:M101	5.24	No	Yes	0	9	9
383	B:B:M101	B:B:Y145	8.38	Yes	Yes	0	9	8
384	B:B:C148	B:B:T102	3.38	Yes	No	0	6	8
385	B:B:G109	B:B:Y105	7.24	No	No	0	5	6
386	B:B:V112	B:B:Y105	3.79	No	No	0	8	6
387	B:B:A106	B:B:F151	8.32	No	Yes	0	6	9
388	B:B:N110	B:B:S108	7.45	No	No	0	4	6
389	B:B:D154	B:B:S108	8.83	No	No	0	6	6
390	B:B:N110	B:B:Y111	3.49	No	Yes	0	4	4
391	B:B:K127	B:B:N110	5.6	No	No	0	4	4
392	B:B:I123	B:B:Y111	3.63	Yes	Yes	1	6	4
393	B:B:N125	B:B:Y111	6.98	No	Yes	0	4	4
394	B:B:F151	B:B:Y111	4.13	Yes	Yes	1	9	4
395	B:B:D154	B:B:Y111	8.05	No	Yes	0	6	4
396	B:B:L126	B:B:V112	4.47	No	No	0	5	8
397	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
398	B:B:C114	B:B:Y124	5.38	Yes	Yes	12	8	6
399	B:B:G115	B:B:L146	5.13	No	Yes	0	9	7
400	B:B:D118	B:B:I120	7	No	No	0	9	6
401	B:B:I120	B:B:S122	3.1	No	No	12	6	8
402	B:B:E138	B:B:I120	4.1	Yes	No	12	6	6
403	B:B:C121	B:B:L146	4.76	No	Yes	1	8	7
404	B:B:C121	B:B:C149	7.28	No	Yes	1	8	8
405	B:B:C121	B:B:I157	3.27	No	Yes	1	8	7
406	B:B:S122	B:B:Y124	3.82	No	Yes	12	8	6
407	B:B:E138	B:B:S122	5.75	Yes	No	12	6	8
408	B:B:I123	B:B:S136	3.1	Yes	No	0	6	4
409	B:B:I123	B:B:L139	4.28	Yes	No	0	6	9
410	B:B:F151	B:B:I123	3.77	Yes	Yes	1	9	6
411	B:B:I123	B:B:I171	5.89	Yes	No	0	6	6
412	B:B:V135	B:B:Y124	7.57	No	Yes	0	4	6
413	B:B:N125	B:B:T128	4.39	No	No	0	4	3
414	B:B:K127	B:B:L126	4.23	No	No	0	4	5
415	B:B:E130	B:B:T128	14.11	Yes	No	0	3	3
416	B:B:E130	B:B:R129	6.98	Yes	No	0	3	3
417	B:B:E130	B:B:N132	6.57	Yes	No	0	3	3
418	B:B:E130	B:B:R134	3.49	Yes	No	0	3	3
419	B:B:E138	B:B:V135	4.28	Yes	No	0	6	4
420	B:B:G174	B:B:R137	4.5	No	No	0	4	5
421	B:B:L139	B:B:W169	12.53	No	Yes	0	9	8
422	B:B:H142	B:B:T159	6.85	Yes	Yes	1	9	9
423	B:B:H142	B:B:S161	15.34	Yes	No	1	9	9
424	B:B:D163	B:B:H142	8.82	Yes	Yes	1	9	9
425	B:B:H142	B:B:W169	4.23	Yes	Yes	1	9	8
426	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
427	B:B:D163	B:B:G144	3.35	Yes	No	0	9	8
428	B:B:G162	B:B:Y145	10.14	No	Yes	1	9	8
429	B:B:D186	B:B:Y145	10.34	Yes	Yes	1	9	8
430	B:B:M188	B:B:Y145	7.18	No	Yes	1	8	8
431	B:B:C149	B:B:L146	6.35	Yes	Yes	1	8	7
432	B:B:L146	B:B:T159	4.42	Yes	Yes	1	7	9
433	B:B:C148	B:B:R150	4.18	Yes	No	0	6	6
434	B:B:C148	B:B:S160	3.44	Yes	Yes	4	6	6
435	B:B:C148	B:B:L190	3.17	Yes	No	4	6	5
436	B:B:C149	B:B:I157	4.91	Yes	Yes	1	8	7
437	B:B:C149	B:B:T159	3.38	Yes	Yes	1	8	9
438	B:B:F151	B:B:I157	6.28	Yes	Yes	1	9	7
439	B:B:L152	B:B:Q156	5.32	Yes	No	0	3	5
440	B:B:L152	B:B:V158	4.47	Yes	No	0	3	5
441	B:B:L152	B:B:L192	5.54	Yes	No	0	3	5
442	B:B:D170	B:B:N155	5.39	No	No	0	9	3
443	B:B:E172	B:B:N155	5.26	No	No	0	6	3
444	B:B:L168	B:B:Q156	5.32	No	No	0	6	5
445	B:B:I157	B:B:I171	4.42	Yes	No	0	7	6
446	B:B:F199	B:B:V158	3.93	Yes	No	0	9	5
447	B:B:T159	B:B:W169	10.92	Yes	Yes	1	9	8
448	B:B:C166	B:B:S160	3.44	No	Yes	0	8	6
449	B:B:S160	B:B:V187	6.46	Yes	Yes	4	6	9
450	B:B:L190	B:B:S160	7.51	No	Yes	4	5	6
451	B:B:G162	B:B:S161	3.71	No	No	1	9	9
452	B:B:D163	B:B:S161	10.31	Yes	No	1	9	9
453	B:B:D186	B:B:G162	6.71	Yes	No	1	9	9
454	B:B:D163	B:B:T165	7.23	Yes	No	0	9	7
455	B:B:T165	B:B:T181	3.14	No	No	0	7	2
456	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
457	B:B:C166	B:B:S201	3.44	No	Yes	0	8	9
458	B:B:A167	B:B:W169	3.89	No	Yes	1	4	8
459	B:B:A167	B:B:Q176	6.06	No	Yes	1	4	4
460	B:B:L168	B:B:T177	4.42	No	No	4	6	4
461	B:B:L168	B:B:T178	5.9	No	No	4	6	4
462	B:B:Q176	B:B:W169	15.33	Yes	Yes	1	4	8
463	B:B:D170	B:B:T173	8.67	No	No	0	9	5
464	B:B:G174	B:B:T173	3.64	No	No	0	4	5
465	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
466	B:B:T177	B:B:T178	4.71	No	No	4	4	4
467	B:B:F180	B:B:T178	7.78	Yes	No	4	7	4
468	B:B:F180	B:B:F199	11.79	Yes	Yes	4	7	9
469	B:B:F180	B:B:W211	12.03	Yes	Yes	4	7	8
470	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
471	B:B:G182	B:B:T181	3.64	No	No	0	6	2
472	B:B:H183	B:B:V187	4.15	Yes	Yes	4	9	9
473	B:B:H183	B:B:S201	5.58	Yes	Yes	4	9	9
474	B:B:A203	B:B:H183	8.78	No	Yes	4	8	9
475	B:B:D205	B:B:H183	6.3	Yes	Yes	4	9	9
476	B:B:H183	B:B:K209	17.03	Yes	Yes	4	9	6
477	B:B:H183	B:B:W211	4.23	Yes	Yes	4	9	8
478	B:B:D205	B:B:T184	5.78	Yes	No	0	9	3
479	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
480	B:B:S201	B:B:V187	3.23	Yes	Yes	4	9	9
481	B:B:A203	B:B:V187	3.39	No	Yes	4	8	9
482	B:B:C204	B:B:M188	3.24	Yes	No	1	7	8
483	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
484	B:B:F199	B:B:L190	4.87	Yes	No	4	9	5
485	B:B:F234	B:B:S191	5.28	No	No	0	5	8
486	B:B:A193	B:B:D195	3.09	No	No	0	4	5
487	B:B:A193	B:B:F234	5.55	No	No	0	4	5
488	B:B:G238	B:B:P194	4.06	No	No	0	7	4
489	B:B:D195	B:B:R197	9.53	No	No	0	5	5
490	B:B:R197	B:B:R214	15.99	No	No	0	5	9
491	B:B:L198	B:B:L210	4.15	No	Yes	0	3	5
492	B:B:D212	B:B:L198	4.07	No	No	0	9	3
493	B:B:F199	B:B:W211	13.03	Yes	Yes	4	9	8
494	B:B:I232	B:B:V200	6.14	Yes	No	3	8	6
495	B:B:F234	B:B:V200	10.49	No	No	0	5	6
496	B:B:F241	B:B:V200	9.18	Yes	No	3	6	6
497	B:B:S201	B:B:W211	7.41	Yes	Yes	4	9	8
498	B:B:G202	B:B:I229	3.53	No	No	0	6	7
499	B:B:A203	B:B:D205	3.09	No	Yes	4	8	9
500	B:B:C204	B:B:D228	12.45	Yes	Yes	1	7	9
501	B:B:D205	B:B:S207	8.83	Yes	No	0	9	5
502	B:B:S207	B:B:T221	3.2	No	No	0	5	7
503	B:B:K209	B:B:W211	8.12	Yes	Yes	4	6	8
504	B:B:C218	B:B:K209	6.47	No	Yes	4	5	6
505	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
506	B:B:L210	B:B:R219	6.07	Yes	No	0	5	5
507	B:B:L210	B:B:Q220	7.99	Yes	Yes	0	5	7
508	B:B:L210	B:B:L255	5.54	Yes	No	0	5	6
509	B:B:C218	B:B:W211	3.92	No	Yes	4	5	8
510	B:B:D212	B:B:E215	18.19	No	No	26	9	3
511	B:B:D212	B:B:R219	13.1	No	No	26	9	5
512	B:B:E215	B:B:R219	5.82	No	No	26	3	5
513	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
514	B:B:F222	B:B:Q220	7.03	Yes	Yes	3	8	7
515	B:B:D258	B:B:Q220	9.14	Yes	Yes	3	7	7
516	B:B:Q220	G:G:I25	4.12	Yes	No	0	7	2
517	B:B:T221	G:G:E22	8.47	No	No	0	7	9
518	B:B:F222	B:B:F241	11.79	Yes	Yes	3	8	6
519	B:B:F222	B:B:F253	10.72	Yes	Yes	3	8	6
520	B:B:D258	B:B:F222	5.97	Yes	Yes	3	7	8
521	B:B:H225	B:B:I229	9.28	Yes	No	3	9	7
522	B:B:H225	B:B:T243	6.85	Yes	Yes	3	9	8
523	B:B:H225	B:B:S245	16.74	Yes	No	3	9	9
524	B:B:D247	B:B:H225	5.04	Yes	Yes	3	9	9
525	B:B:H225	B:B:R251	14.67	Yes	Yes	3	9	8
526	B:B:D247	B:B:E226	12.99	Yes	No	0	9	3
527	B:B:D228	B:B:S227	4.42	Yes	No	0	9	6
528	B:B:D246	B:B:S227	5.89	No	No	0	9	6
529	B:B:D247	B:B:S227	4.42	Yes	No	0	9	6
530	B:B:I229	B:B:T243	3.04	No	Yes	3	7	8
531	B:B:D246	B:B:N230	6.73	No	No	1	9	9
532	B:B:A231	B:B:V276	5.09	No	No	0	5	6
533	B:B:F241	B:B:I232	5.02	Yes	Yes	3	6	8
534	B:B:I232	B:B:T243	4.56	Yes	Yes	3	8	8
535	B:B:F235	B:B:P236	10.11	Yes	Yes	20	6	7
536	B:B:F235	B:B:N237	6.04	Yes	Yes	0	6	5
537	B:B:F235	B:B:F278	9.65	Yes	Yes	20	6	7
538	B:B:F235	B:B:G282	4.52	Yes	No	20	6	9
539	B:B:F278	B:B:P236	4.33	Yes	Yes	20	7	7
540	B:B:G282	B:B:P236	4.06	No	Yes	20	9	7
541	B:B:P236	G:G:Y40	5.56	Yes	No	0	7	6
542	B:B:G238	B:B:N237	3.39	No	Yes	0	7	5
543	B:B:N237	B:B:N239	9.54	Yes	No	0	5	2
544	B:B:N237	G:G:Y40	6.98	Yes	No	0	5	6
545	B:B:N239	B:B:R256	7.23	No	No	0	2	9
546	B:B:F241	B:B:F253	8.57	Yes	Yes	3	6	6
547	B:B:A242	B:B:L285	3.15	No	No	0	4	6
548	B:B:F253	B:B:T243	7.78	Yes	Yes	3	6	8
549	B:B:G244	B:B:I273	5.29	No	No	0	5	6
550	B:B:D247	B:B:S245	8.83	Yes	No	3	9	9
551	B:B:D247	B:B:T249	7.23	Yes	No	0	9	6
552	B:B:R251	B:B:T249	9.06	Yes	No	0	8	6
553	B:B:S265	B:B:T249	4.8	No	No	0	2	6
554	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
555	B:B:C250	B:B:I273	4.91	No	No	0	8	6
556	B:B:F253	B:B:R251	4.28	Yes	Yes	3	6	8
557	B:B:E260	B:B:R251	15.12	Yes	Yes	3	6	8
558	B:B:R251	B:B:T263	11.64	Yes	No	3	8	1
559	B:B:L252	B:B:L261	6.92	No	No	0	7	5
560	B:B:L252	B:B:Y264	7.03	No	Yes	0	7	5
561	B:B:E260	B:B:F253	7	Yes	Yes	3	6	6
562	B:B:A257	B:B:D254	4.63	No	No	0	7	9
563	B:B:D254	B:B:L261	6.79	No	No	0	9	5
564	B:B:D254	G:G:A33	3.09	No	No	0	9	7
565	B:B:R256	G:G:I28	8.77	No	No	0	9	4
566	B:B:R256	G:G:D36	9.53	No	No	0	9	5
567	B:B:D258	G:G:R27	9.53	Yes	Yes	3	7	8
568	B:B:Q259	G:G:V30	5.73	Yes	No	0	6	8
569	B:B:E260	B:B:T263	7.06	Yes	No	3	6	1
570	B:B:M262	B:B:Y264	9.58	Yes	Yes	0	4	5
571	B:B:A302	B:B:M262	4.83	No	Yes	0	2	4
572	B:B:S265	B:B:T263	3.2	No	No	0	2	1
573	B:B:L285	B:B:Y264	7.03	No	Yes	0	6	5
574	B:B:W297	B:B:Y264	9.65	No	Yes	0	8	5
575	B:B:H266	B:B:N268	6.38	No	No	0	4	4
576	B:B:H266	B:B:R304	6.77	No	No	0	4	5
577	B:B:I269	B:B:Y289	6.04	No	Yes	0	4	7
578	B:B:I269	B:B:R304	6.26	No	No	0	4	5
579	B:B:C271	B:B:Y289	4.03	No	Yes	5	5	7
580	B:B:C271	B:B:D290	3.11	No	Yes	5	5	6
581	B:B:C271	B:B:D291	7.78	No	No	5	5	8
582	B:B:D290	B:B:G272	5.03	Yes	No	0	6	4
583	B:B:I273	B:B:Y289	9.67	No	Yes	0	6	7
584	B:B:S275	B:B:T274	4.8	No	No	0	8	8
585	B:B:R314	B:B:T274	5.17	Yes	No	0	8	8
586	B:B:T274	B:B:V315	3.17	No	Yes	0	8	7
587	B:B:L318	B:B:S275	9.01	No	No	0	6	8
588	B:B:S277	B:B:V320	4.85	No	No	0	5	7
589	B:B:F278	B:B:G282	3.01	Yes	No	20	7	9
590	B:B:F278	B:B:L285	13.4	Yes	No	0	7	6
591	B:B:L284	B:B:S279	4.5	No	No	0	5	9
592	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
593	B:B:G324	B:B:K280	3.49	No	No	0	9	1
594	B:B:S281	G:G:C41	3.44	No	No	0	9	7
595	B:B:S281	G:G:D48	5.89	No	Yes	0	9	9
596	B:B:D298	B:B:R283	13.1	No	Yes	16	9	9
597	B:B:L300	B:B:R283	8.5	No	Yes	0	6	9
598	B:B:R283	G:G:L51	4.86	Yes	Yes	0	9	6
599	B:B:L284	B:B:V296	5.96	No	No	0	5	5
600	B:B:L284	G:G:L51	4.15	No	Yes	0	5	6
601	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
602	B:B:G288	B:B:V315	3.68	No	Yes	0	7	7
603	B:B:D291	B:B:Y289	3.45	No	Yes	5	8	7
604	B:B:N295	B:B:Y289	15.12	Yes	Yes	5	6	7
605	B:B:W297	B:B:Y289	5.79	No	Yes	5	8	7
606	B:B:D290	B:B:R314	8.34	Yes	Yes	5	6	8
607	B:B:D291	B:B:N293	4.04	No	No	0	8	5
608	B:B:A309	B:B:N293	4.69	No	No	0	3	5
609	B:B:C294	B:B:L308	4.76	No	No	0	5	7
610	B:B:C294	B:B:V315	5.12	No	Yes	9	5	7
611	B:B:C294	B:B:T329	3.38	No	Yes	9	5	8
612	B:B:N295	B:B:W297	4.52	Yes	No	5	6	8
613	B:B:N295	B:B:R304	15.67	Yes	No	0	6	5
614	B:B:A305	B:B:V296	3.39	No	No	0	4	5
615	B:B:D298	B:B:K301	8.3	No	No	0	9	5
616	B:B:L300	G:G:C41	3.17	No	No	0	6	7
617	B:B:D303	B:B:K301	5.53	No	No	0	2	5
618	B:B:L308	B:B:W339	13.67	No	Yes	0	7	9
619	B:B:G310	R:R:R476	3	No	No	0	5	7
620	B:B:H311	B:B:V315	4.15	Yes	Yes	9	9	7
621	B:B:H311	B:B:T329	5.48	Yes	Yes	9	9	8
622	B:B:H311	B:B:S331	12.55	Yes	No	9	9	9
623	B:B:D333	B:B:H311	8.82	Yes	Yes	9	9	9
624	B:B:H311	B:B:K337	9.17	Yes	Yes	9	9	6
625	B:B:D312	B:B:D333	7.98	No	Yes	0	5	9
626	B:B:N313	B:B:W332	6.78	No	Yes	0	7	9
627	B:B:R314	B:B:W332	24.99	Yes	Yes	5	8	9
628	B:B:T329	B:B:V315	4.76	Yes	Yes	9	8	7
629	B:B:C317	B:B:S316	3.44	No	No	0	7	9
630	B:B:S316	B:B:W332	3.71	No	Yes	0	9	9
631	B:B:L318	B:B:T329	4.42	No	Yes	0	6	8
632	B:B:V320	B:B:V327	3.21	No	No	0	7	6
633	B:B:D323	B:B:T321	7.23	No	No	8	7	7
634	B:B:D323	B:B:M325	5.54	No	Yes	8	7	5
635	B:B:M325	G:G:P49	5.03	Yes	No	0	5	7
636	B:B:M325	G:G:N59	5.61	Yes	Yes	8	5	9
637	B:B:M325	G:G:P60	6.71	Yes	Yes	8	5	9
638	B:B:A326	B:B:N340	3.13	No	No	0	7	9
639	B:B:A326	G:G:F61	5.55	No	Yes	0	7	8
640	B:B:T329	B:B:W339	8.49	Yes	Yes	9	8	9
641	B:B:D333	B:B:S331	10.31	Yes	No	9	9	9
642	B:B:D333	B:B:F335	11.94	Yes	No	0	9	4
643	B:B:F335	B:B:S334	5.28	No	No	0	4	4
644	B:B:K337	B:B:W339	5.8	Yes	Yes	9	6	9
645	B:B:I338	G:G:F61	3.77	No	Yes	0	5	8
646	B:B:N340	G:G:N59	10.9	No	Yes	0	9	9
647	G:G:I9	G:G:T6	7.6	No	No	0	2	3
648	G:G:E17	G:G:K14	9.45	No	No	0	6	4
649	G:G:E22	G:G:Q18	6.37	No	No	0	9	9
650	G:G:I25	G:G:R27	6.26	No	Yes	0	2	8
651	G:G:I28	G:G:K32	11.63	No	No	0	4	5
652	G:G:A33	G:G:I28	3.25	No	No	0	7	4
653	G:G:H44	G:G:Y40	21.78	No	No	0	6	6
654	G:G:E47	G:G:H44	3.69	No	No	0	3	6
655	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
656	G:G:D48	G:G:L51	6.79	Yes	Yes	0	9	6
657	G:G:P49	G:G:V54	3.53	No	No	0	7	6
658	G:G:P55	G:G:V54	3.53	No	No	0	5	6
659	G:G:E58	G:G:P55	3.14	No	No	0	5	5
660	G:G:A56	G:G:R62	8.3	No	No	0	4	7
661	G:G:N59	G:G:P60	6.52	Yes	Yes	8	9	9
662	G:G:F61	G:G:N59	4.83	Yes	Yes	8	8	9
663	G:G:N59	G:G:R62	10.85	Yes	No	0	9	7
664	G:G:F61	G:G:P60	4.33	Yes	Yes	8	8	9
665	R:R:A234	R:R:Y195	4	No	Yes	0	8	7
666	R:R:I237	R:R:Y195	8.46	Yes	Yes	0	7	7
667	R:R:F453	R:R:V197	13.11	Yes	No	0	6	5
668	R:R:G452	R:R:S198	3.71	No	No	0	9	9
669	R:R:L199	R:R:M231	8.48	No	No	0	7	8
670	R:R:F453	R:R:S201	6.61	Yes	No	0	6	8
671	R:R:F227	R:R:L202	3.65	No	No	0	9	9
672	R:R:M231	R:R:T203	6.02	No	No	0	8	3
673	R:R:I208	R:R:V204	3.07	No	No	0	8	5
674	R:R:A205	R:R:F227	4.16	No	No	27	9	9
675	R:R:A205	R:R:C460	3.61	No	No	27	9	9
676	R:R:M224	R:R:V206	4.56	Yes	No	0	5	5
677	R:R:L209	R:R:N220	4.12	No	No	0	7	9
678	R:R:L209	R:R:M224	5.65	No	Yes	0	7	5
679	R:R:F212	R:R:Y211	8.25	Yes	No	0	7	2
680	R:R:F212	R:R:L215	6.09	Yes	Yes	6	7	9
681	R:R:E469	R:R:F212	15.16	Yes	Yes	6	9	7
682	R:R:H216	R:R:R213	14.67	No	No	0	8	8
683	R:R:E469	R:R:R214	6.98	Yes	No	0	9	7
684	R:R:E465	R:R:L215	3.98	Yes	Yes	6	9	9
685	R:R:L215	R:R:V466	5.96	Yes	No	6	9	9
686	R:R:E469	R:R:L215	14.58	Yes	Yes	6	9	9
687	R:R:H216	R:R:Y221	13.07	No	No	0	8	7
688	R:R:T218	R:R:Y305	9.99	No	No	0	7	8
689	R:R:L321	R:R:T218	11.79	No	No	0	6	7
690	R:R:N220	R:R:R219	9.64	No	Yes	6	9	9
691	R:R:H223	R:R:R219	7.9	Yes	Yes	6	9	9
692	R:R:E465	R:R:R219	3.49	Yes	Yes	6	9	9
693	R:R:R219	W:W:?1	3.18	Yes	Yes	6	9	0
694	R:R:H223	R:R:N220	5.1	Yes	No	6	9	9
695	R:R:E302	R:R:I222	6.83	Yes	No	0	9	9
696	R:R:E302	R:R:H223	9.85	Yes	Yes	6	9	9
697	R:R:H223	W:W:?1	8.09	Yes	Yes	6	9	0
698	R:R:H225	R:R:W298	15.87	No	Yes	19	8	9
699	R:R:H225	R:R:W329	8.46	No	Yes	19	8	9
700	R:R:F230	R:R:L226	9.74	Yes	No	0	8	9
701	R:R:E302	R:R:L226	10.6	Yes	No	0	9	9
702	R:R:C460	R:R:F227	4.19	No	No	27	9	9
703	R:R:L228	R:R:L232	4.15	No	No	0	4	8
704	R:R:L228	R:R:W329	5.69	No	Yes	0	4	9
705	R:R:S229	R:R:T294	4.8	No	No	0	9	8
706	R:R:N295	R:R:S229	8.94	No	No	0	8	9
707	R:R:F230	R:R:N295	6.04	Yes	No	0	8	8
708	R:R:F230	R:R:I299	3.77	Yes	No	0	8	9
709	R:R:F230	R:R:F417	4.29	Yes	No	0	8	9
710	R:R:F230	R:R:V455	10.49	Yes	No	0	8	9
711	R:R:F291	R:R:L232	15.83	No	No	0	5	8
712	R:R:I237	R:R:R233	3.76	Yes	Yes	14	7	8
713	R:R:L292	R:R:R233	4.86	No	Yes	0	6	8
714	R:R:N295	R:R:R233	10.85	No	Yes	0	8	8
715	R:R:R233	R:R:Y296	5.14	Yes	Yes	14	8	7
716	R:R:N448	R:R:R233	3.62	No	Yes	14	6	8
717	R:R:Q451	R:R:R233	17.52	No	Yes	0	9	8
718	R:R:F291	R:R:S236	6.61	No	No	0	5	7
719	R:R:I237	R:R:N448	4.25	Yes	No	14	7	6
720	R:R:F238	R:R:V239	3.93	No	No	0	7	5
721	R:R:K240	R:R:L244	4.23	No	No	0	7	5
722	R:R:K240	R:R:V285	4.55	No	No	0	7	6
723	R:R:F288	R:R:K240	17.37	No	No	0	7	7
724	R:R:R282	R:R:R343	14.93	No	No	0	8	8
725	R:R:T286	R:R:V340	3.17	No	No	0	7	5
726	R:R:L289	R:R:W339	6.83	No	Yes	0	7	8
727	R:R:I363	R:R:L289	4.28	No	No	0	7	7
728	R:R:F291	R:R:Y290	9.28	No	Yes	0	5	9
729	R:R:T294	R:R:Y290	8.74	No	Yes	19	8	9
730	R:R:W329	R:R:Y290	5.79	Yes	Yes	19	9	9
731	R:R:A333	R:R:Y290	4	No	Yes	0	5	9
732	R:R:A293	R:R:I367	3.25	No	Yes	0	6	7
733	R:R:T294	R:R:W329	4.85	No	Yes	19	8	9
734	R:R:I367	R:R:Y296	4.84	Yes	Yes	14	7	7
735	R:R:I371	R:R:Y296	3.63	No	Yes	14	7	7
736	R:R:Y296	R:R:Y421	8.94	Yes	Yes	14	7	8
737	R:R:F327	R:R:Y297	3.09	No	Yes	21	5	6
738	R:R:L331	R:R:Y297	4.69	No	Yes	21	4	6
739	R:R:P332	R:R:Y297	6.95	No	Yes	21	9	6
740	R:R:S370	R:R:Y297	7.63	No	Yes	0	7	6
741	R:R:V301	R:R:W298	3.68	No	Yes	0	8	9
742	R:R:G328	R:R:W298	8.44	No	Yes	0	9	9
743	R:R:W298	R:R:W329	21.56	Yes	Yes	19	9	9
744	R:R:I299	W:W:?1	8.98	No	Yes	0	9	0
745	R:R:L300	R:R:S370	7.51	No	No	0	8	7
746	R:R:L300	R:R:L373	6.92	No	No	0	8	7
747	R:R:L300	R:R:N374	4.12	No	No	0	8	9
748	R:R:F324	R:R:V301	5.24	No	No	0	7	8
749	R:R:E302	W:W:?1	12.5	Yes	Yes	6	9	0
750	R:R:L304	R:R:L377	5.54	No	No	0	5	7
751	R:R:L309	R:R:Y305	11.72	No	No	0	8	8
752	R:R:I310	R:R:L306	4.28	No	No	0	8	9
753	R:R:I381	R:R:L306	4.28	No	No	0	9	9
754	R:R:F311	R:R:H307	11.31	Yes	No	0	6	8
755	R:R:H307	R:R:L377	10.29	No	No	0	8	7
756	R:R:H307	R:R:N380	7.65	No	No	0	8	8
757	R:R:F311	R:R:I310	5.02	Yes	No	0	6	8
758	R:R:F311	R:R:V384	3.93	Yes	No	0	6	8
759	R:R:L321	R:R:W322	6.83	No	No	0	6	3
760	R:R:T325	R:R:W322	6.06	No	No	0	5	3
761	R:R:F327	R:R:L331	7.31	No	No	21	5	4
762	R:R:L331	R:R:P332	3.28	No	No	21	4	9
763	R:R:F335	R:R:I363	3.77	No	No	0	5	7
764	R:R:F335	R:R:P366	8.67	No	No	0	5	9
765	R:R:I362	R:R:V338	3.07	No	No	0	8	5
766	R:R:V340	R:R:W339	3.68	No	Yes	0	5	8
767	R:R:I362	R:R:W339	4.7	No	Yes	0	8	8
768	R:R:L346	R:R:T345	8.84	No	No	0	3	3
769	R:R:K360	R:R:W361	9.28	No	No	0	7	8
770	R:R:Q364	R:R:Y421	5.64	No	Yes	0	7	8
771	R:R:P366	R:R:V365	3.53	No	No	0	9	5
772	R:R:L368	R:R:V365	4.47	No	No	0	4	5
773	R:R:I367	R:R:Y421	9.67	Yes	Yes	14	7	8
774	R:R:G418	R:R:I371	5.29	No	No	0	9	7
775	R:R:I371	R:R:Y421	3.63	No	Yes	14	7	8
776	R:R:N374	R:R:P415	3.26	No	No	0	9	9
777	R:R:F375	R:R:F378	3.22	No	Yes	0	7	9
778	R:R:F375	R:R:I379	6.28	No	No	0	7	5
779	R:R:F378	R:R:V382	3.93	Yes	No	0	9	7
780	R:R:F378	R:R:M414	3.73	Yes	No	0	9	8
781	R:R:F378	R:R:P415	7.22	Yes	No	0	9	9
782	R:R:I381	R:R:L413	4.28	No	No	0	9	9
783	R:R:T410	R:R:V382	4.76	No	No	0	9	7
784	R:R:K388	R:R:V384	4.55	Yes	No	0	9	8
785	R:R:L385	R:R:S409	3	No	No	0	8	9
786	R:R:A386	R:R:L406	3.15	No	No	0	6	8
787	R:R:R390	R:R:T387	5.17	No	No	0	6	7
788	R:R:E391	R:R:T387	4.23	No	No	0	7	7
789	R:R:L389	R:R:Q402	7.99	No	No	0	8	6
790	R:R:K405	R:R:L389	7.05	No	No	0	8	8
791	R:R:L389	R:R:L406	4.15	No	No	0	8	8
792	R:R:N393	R:R:T392	4.39	No	Yes	11	7	7
793	R:R:C397	R:R:T392	3.38	No	Yes	0	5	7
794	R:R:C397	R:R:Q402	7.63	No	No	0	5	6
795	R:R:D398	R:R:R400	3.57	No	No	0	6	8
796	R:R:D398	R:R:Q401	3.92	No	No	0	6	6
797	R:R:R400	R:R:Y403	6.17	No	No	28	8	7
798	R:R:R400	R:R:R404	38.38	No	No	28	8	6
799	R:R:Q401	R:R:Q402	3.84	No	No	0	6	6
800	R:R:R404	R:R:Y403	4.12	No	No	28	6	7
801	R:R:K405	R:R:S409	7.65	No	No	0	8	9
802	R:R:L411	R:R:M414	5.65	No	No	0	8	8
803	R:R:L416	R:R:M414	7.07	No	No	0	9	8
804	R:R:L416	W:W:?1	7.25	No	Yes	0	9	0
805	R:R:F417	R:R:Q451	4.68	No	No	0	9	9
806	R:R:F417	W:W:?1	12.77	No	Yes	0	9	0
807	R:R:F447	R:R:H420	5.66	No	No	0	5	8
808	R:R:F424	R:R:M425	8.71	No	No	0	7	6
809	R:R:F450	R:R:L446	9.74	No	No	0	7	5
810	R:R:G452	R:R:Q451	4.93	No	No	0	9	9
811	R:R:F453	R:R:I457	8.79	Yes	No	0	6	6
812	R:R:F454	R:R:I458	5.02	No	No	0	6	8
813	R:R:F454	W:W:?1	8.94	No	Yes	0	6	0
814	R:R:V455	R:R:Y459	3.79	No	No	0	9	8
815	R:R:Y459	W:W:?1	25.81	No	Yes	0	8	0
816	R:R:E465	R:R:N463	13.15	Yes	No	6	9	9
817	R:R:N463	R:R:V466	5.91	No	No	6	9	9
818	R:R:N463	W:W:?1	9.36	No	Yes	6	9	0
819	R:R:E465	R:R:V466	5.7	Yes	No	6	9	9
820	R:R:W474	R:R:W477	4.69	No	No	0	5	4
821	R:R:T478	R:R:W477	6.06	No	No	0	4	4
822	A:A:L297	A:A:V301	2.98	Yes	No	0	8	7
823	B:B:V327	G:G:L50	2.98	No	No	0	6	9
824	R:R:L368	R:R:V372	2.98	No	No	0	4	4
825	R:R:L416	R:R:V419	2.98	No	No	0	9	7
826	B:B:N293	B:B:V307	2.96	No	No	0	5	3
827	B:B:N295	B:B:V307	2.96	Yes	No	0	6	3
828	B:B:L146	B:B:T102	2.95	Yes	No	0	7	8
829	B:B:L152	B:B:T196	2.95	Yes	No	0	3	1
830	G:G:L51	G:G:T52	2.95	Yes	No	0	6	4
831	R:R:D241	R:R:S246	2.94	No	No	0	8	4
832	R:R:I363	R:R:I367	2.94	No	Yes	0	7	7
833	A:A:N218	A:A:T40	2.92	No	No	0	4	7
834	B:B:I33	G:G:M38	2.92	No	No	0	3	4
835	A:A:I26	B:B:K89	2.91	No	Yes	0	9	9
836	B:B:D322	B:B:T65	2.89	No	No	0	1	1
837	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
838	B:B:L4	G:G:I9	2.85	No	No	0	4	2
839	B:B:E10	G:G:V16	2.85	No	No	0	8	7
840	B:B:I171	B:B:N155	2.83	No	No	0	6	3
841	B:B:Q175	B:B:T173	2.83	No	No	0	4	5
842	R:R:L202	R:R:M231	2.83	No	No	0	9	8
843	B:B:G310	B:B:W339	2.81	No	Yes	0	5	9
844	A:A:A269	A:A:F345	2.77	No	Yes	0	9	8
845	A:A:A337	A:A:F315	2.77	No	Yes	0	8	6
846	B:B:A21	G:G:R27	2.77	No	Yes	0	4	8
847	B:B:A104	B:B:R150	2.77	No	No	0	7	6
848	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
849	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
850	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
851	B:B:L261	G:G:L37	2.77	No	No	0	5	7
852	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
853	R:R:A386	R:R:R383	2.77	No	No	0	6	8
854	R:R:L407	R:R:L411	2.77	No	No	0	8	8
855	R:R:H420	R:R:V419	2.77	No	No	0	8	7
856	R:R:H225	R:R:T325	2.74	No	No	0	8	5
857	A:A:Q31	R:R:K319	2.71	No	No	0	4	6
858	R:R:K360	R:R:Q364	2.71	No	No	0	7	7
859	B:B:A299	B:B:Y264	2.67	No	Yes	0	5	5
860	B:B:L14	B:B:Q13	2.66	No	No	0	8	1
861	B:B:D153	B:B:D154	2.66	No	No	0	5	6
862	A:A:E299	A:A:L296	2.65	No	Yes	0	6	6
863	R:R:F453	R:R:S198	2.64	Yes	No	0	6	9
864	R:R:F450	R:R:S449	2.64	No	No	0	7	9
865	B:B:E12	B:B:N16	2.63	No	No	0	4	1
866	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
867	R:R:R343	R:R:V340	2.62	No	No	0	8	5
868	A:A:D229	A:A:E230	2.6	No	Yes	0	8	9
869	A:A:R42	A:A:T40	2.59	No	No	0	9	7
870	A:A:R356	A:A:T284	2.59	Yes	No	0	2	4
871	B:B:E12	B:B:Q9	2.55	No	No	0	4	3
872	B:B:S147	B:B:Y145	2.54	No	Yes	0	9	8
873	A:A:F212	A:A:I62	2.51	Yes	No	0	9	9
874	R:R:F212	R:R:I208	2.51	Yes	No	0	7	8
875	R:R:K472	R:R:R476	2.48	No	No	0	7	7
876	R:R:V285	R:R:W339	2.45	No	Yes	0	6	8
877	R:R:F230	R:R:L202	2.44	Yes	No	0	8	9
878	A:A:L46	A:A:R231	2.43	No	No	0	8	9
879	B:B:L7	G:G:R13	2.43	Yes	No	0	8	6
880	B:B:F292	B:B:N313	2.42	No	No	0	4	7
881	R:R:M224	R:R:Y221	2.39	Yes	No	0	5	7
882	R:R:I470	R:R:W474	2.35	No	No	0	5	5
883	B:B:R19	B:B:R22	2.13	No	Yes	0	4	6
884	A:A:G206	A:A:G226	2.11	No	No	0	8	9
885	A:A:G225	A:A:G226	2.11	No	No	0	9	9
886	R:R:F238	R:R:Y195	2.06	No	Yes	0	7	7
887	R:R:G330	R:R:P332	2.03	No	No	0	7	9
888	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
889	B:B:C317	B:B:G330	1.96	No	No	0	7	5
890	B:B:A140	B:B:G141	1.95	No	No	0	5	5
891	B:B:A305	B:B:G306	1.95	No	No	0	4	4
892	R:R:A394	R:R:G395	1.95	No	No	0	5	5
893	B:B:G41	B:B:V40	1.84	No	No	0	1	3
894	B:B:G244	B:B:V276	1.84	No	No	0	5	6
895	R:R:G194	R:R:V193	1.84	No	No	0	9	6
896	R:R:G194	R:R:V197	1.84	No	No	0	9	5
897	B:B:G131	B:B:T128	1.82	No	No	0	4	3
898	B:B:G224	B:B:T223	1.82	No	No	0	6	2
899	B:B:A60	B:B:C103	1.81	No	No	0	7	8
900	G:G:P55	G:G:S57	1.78	No	No	0	5	6
901	A:A:P326	A:A:T325	1.75	No	No	0	1	2
902	B:B:P107	B:B:T65	1.75	No	No	0	6	1
903	G:G:P53	G:G:T52	1.75	No	No	0	8	4
904	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
905	B:B:C233	B:B:S277	1.72	No	No	0	3	5
906	A:A:A48	A:A:S51	1.71	No	Yes	0	8	9
907	A:A:C365	A:A:V367	1.71	No	No	0	8	9
908	R:R:A456	R:R:S201	1.71	No	No	0	8	8
909	R:R:A242	R:R:S246	1.71	No	No	0	4	4
910	R:R:C281	R:R:V283	1.71	No	No	0	9	4
911	R:R:A313	R:R:S308	1.71	No	No	0	7	7
912	A:A:A372	A:A:V214	1.7	No	No	0	8	6
913	A:A:A298	A:A:V334	1.7	No	No	0	4	4
914	B:B:A11	G:G:V16	1.7	No	No	0	5	7
915	R:R:A284	R:R:V239	1.7	No	No	0	6	5
916	R:R:A284	R:R:V243	1.7	No	No	0	6	5
917	R:R:G303	R:R:N374	1.7	No	No	0	9	9
918	A:A:A366	A:A:T55	1.68	No	No	0	9	9
919	A:A:D354	A:A:G355	1.68	No	No	0	3	2
920	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
921	B:B:E260	B:B:G224	1.64	Yes	No	0	6	6
922	R:R:C462	R:R:I457	1.64	No	No	0	6	6
923	R:R:G464	R:R:Q467	1.64	No	No	0	7	8
924	B:B:A28	B:B:I33	1.62	No	No	0	4	3
925	B:B:A248	B:B:I269	1.62	No	No	0	5	4
926	B:B:D38	B:B:P39	1.61	No	No	0	1	1
927	R:R:A210	R:R:M224	1.61	No	Yes	0	4	5
928	A:A:S54	A:A:T55	1.6	No	No	0	9	9
929	G:G:S8	G:G:T6	1.6	No	No	0	4	3
930	A:A:T40	A:A:V36	1.59	No	No	0	7	2
931	R:R:T286	R:R:V336	1.59	No	No	0	7	7
932	R:R:T325	R:R:V326	1.59	No	No	0	5	4
933	B:B:L7	G:G:A12	1.58	Yes	No	0	8	5
934	B:B:A11	G:G:L15	1.58	No	No	0	5	2
935	B:B:A11	G:G:L19	1.58	No	No	0	5	9
936	B:B:L14	G:G:A23	1.58	No	No	0	8	8
937	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
938	R:R:A313	R:R:L309	1.58	No	No	0	7	8
939	A:A:E327	A:A:P328	1.57	No	No	0	4	1
940	A:A:C365	A:A:D295	1.56	No	No	0	8	9
941	G:G:A23	G:G:N24	1.56	No	No	0	8	1
942	R:R:V412	W:W:?1	1.56	No	Yes	0	8	0
943	A:A:D323	R:R:A394	1.54	No	No	0	4	5
944	B:B:A21	B:B:D20	1.54	No	No	0	4	2
945	R:R:I376	R:R:V372	1.54	No	No	0	4	4
946	A:A:K58	A:A:S54	1.53	No	No	0	9	9
947	A:A:M221	A:A:V57	1.52	No	No	0	8	7
948	G:G:K20	G:G:V16	1.52	No	No	0	6	7
949	A:A:A316	A:A:E309	1.51	No	No	0	2	4
950	B:B:L286	B:B:S277	1.5	No	No	0	7	5
951	R:R:L199	R:R:V235	1.49	No	No	0	7	4
952	R:R:L346	R:R:V342	1.49	No	No	0	3	5
953	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
954	G:G:A43	G:G:H44	1.46	No	No	0	4	6
955	A:A:K300	A:A:K305	1.44	Yes	No	0	9	3
956	B:B:E3	B:B:S2	1.44	No	No	0	5	5
957	B:B:I18	G:G:L19	1.43	No	No	0	7	9
958	R:R:I422	R:R:L368	1.43	No	No	0	5	4
959	B:B:K15	G:G:L19	1.41	No	No	0	6	9
960	B:B:D38	B:B:I37	1.4	No	Yes	0	1	2
961	R:R:D241	R:R:I237	1.4	No	Yes	0	8	7
962	R:R:C462	R:R:F461	1.4	No	No	0	6	8
963	R:R:C281	R:R:R282	1.39	No	No	0	9	8
964	B:B:L4	B:B:L7	1.38	No	Yes	0	4	8
965	G:G:A10	G:G:R13	1.38	No	No	0	2	6
966	R:R:A386	R:R:R390	1.38	No	No	0	6	6
967	R:R:E469	R:R:I470	1.37	Yes	No	0	9	5
968	G:G:M21	G:G:Q18	1.36	No	No	0	1	9
969	R:R:M425	R:R:Q364	1.36	No	No	0	6	7
970	G:G:E47	G:G:K46	1.35	No	No	0	3	1
971	R:R:F287	R:R:V283	1.31	No	No	0	3	4
972	R:R:F335	R:R:V334	1.31	No	No	0	5	4
973	R:R:S449	R:R:Y195	1.27	No	Yes	0	9	7
974	R:R:S316	R:R:Y320	1.27	No	No	0	7	4
975	G:G:K14	G:G:R13	1.24	No	No	0	4	6
976	R:R:F311	R:R:M312	1.24	Yes	No	0	6	5
977	B:B:Q9	B:B:R8	1.17	No	No	0	3	3
978	B:B:Q44	B:B:R42	1.17	No	No	0	4	2
979	B:B:Q44	B:B:R46	1.17	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:S51	4.036	5	15	9
2	A:A:K53	5.918	5	15	9
3	A:A:F212	7.7125	4	0	9
4	A:A:F219	7.01167	6	10	8
5	A:A:F222	9.312	5	17	7
6	A:A:Q227	5.98	4	0	9
7	A:A:E230	5.4375	4	1	9
8	A:A:K233	5.62	6	1	9
9	A:A:W234	6.916	5	0	9
10	A:A:F238	9.4725	4	0	9
11	A:A:V247	4.635	4	15	7
12	A:A:D252	9.31	4	18	8
13	A:A:Y253	9.97	4	2	8
14	A:A:R265	11.325	4	18	9
15	A:A:F273	5.00667	6	2	9
16	A:A:W277	10.628	5	2	6
17	A:A:W281	11.5783	6	5	5
18	A:A:L289	5.5825	4	0	9
19	A:A:F290	5.38	5	23	9
20	A:A:Q294	7.0825	4	2	6
21	A:A:L296	4.1675	4	0	6
22	A:A:L297	3.705	4	2	8
23	A:A:K300	8.6625	4	2	9
24	A:A:F312	5.114	5	13	8
25	A:A:E314	5.708	5	13	6
26	A:A:F315	10.1233	6	13	6
27	A:A:Y318	7.74	5	13	6
28	A:A:P321	4.8975	4	0	5
29	A:A:E330	7.5425	4	2	3
30	A:A:K338	8.9225	4	2	5
31	A:A:Y339	6.76	5	2	3
32	A:A:F340	11.782	5	13	7
33	A:A:R342	6.516	5	2	4
34	A:A:E344	6.958	5	13	5
35	A:A:F345	6.346	5	0	8
36	A:A:S349	5.81	4	2	7
37	A:A:R356	7.2275	4	2	2
38	A:A:Y358	6.69	5	11	4
39	A:A:F363	9.672	5	2	5
40	A:A:N371	7.72	4	23	9
41	A:A:R373	6.5725	4	10	5
42	A:A:F376	5.96571	7	10	8
43	A:A:R385	7.37833	6	11	5
44	A:A:Y391	6.84	4	6	4
45	B:B:L7	2.934	5	0	8
46	B:B:R22	6.05	5	3	6
47	B:B:T34	5.2175	4	16	5
48	B:B:I37	3.835	4	16	2
49	B:B:R48	8.1725	4	0	7
50	B:B:H54	10.214	5	7	9
51	B:B:K57	11.565	4	5	9
52	B:B:W63	8.552	5	8	7
53	B:B:V71	3.9675	4	0	8
54	B:B:Q75	7.0225	4	0	9
55	B:B:D76	6.352	5	22	9
56	B:B:L79	5.5175	4	12	7
57	B:B:W82	11.994	5	7	9
58	B:B:D83	9.5775	4	7	8
59	B:B:N88	9.0975	4	7	7
60	B:B:K89	5.945	6	7	9
61	B:B:I93	5.925	4	0	7
62	B:B:L95	5.152	5	12	8
63	B:B:W99	9.02167	6	17	9
64	B:B:M101	7.315	4	0	9
65	B:B:Y111	5.256	5	1	4
66	B:B:C114	4.9775	4	12	8
67	B:B:I123	4.134	5	1	6
68	B:B:Y124	6.218	5	12	6
69	B:B:E130	7.7875	4	0	3
70	B:B:E138	7.0225	4	12	6
71	B:B:H142	8.81	4	1	9
72	B:B:Y145	6.98857	7	1	8
73	B:B:L146	4.722	5	1	7
74	B:B:C148	3.5425	4	4	6
75	B:B:C149	5.48	4	1	8
76	B:B:F151	4.61714	7	1	9
77	B:B:L152	4.57	4	0	3
78	B:B:I157	4.72	4	1	7
79	B:B:T159	6.3925	4	1	9
80	B:B:S160	5.2125	4	4	6
81	B:B:D163	7.388	5	1	9
82	B:B:W169	9.38	5	1	8
83	B:B:Q176	7.53	4	1	4
84	B:B:F180	7.76	5	4	7
85	B:B:H183	7.67833	6	4	9
86	B:B:D186	6.74	5	1	9
87	B:B:V187	4.3075	4	4	9
88	B:B:F199	7.248	5	4	9
89	B:B:S201	4.915	4	4	9
90	B:B:C204	5.122	5	1	7
91	B:B:D205	6	4	4	9
92	B:B:K209	10.1575	4	4	6
93	B:B:L210	5.9375	4	0	5
94	B:B:W211	8.12333	6	4	8
95	B:B:Q220	7.07	4	3	7
96	B:B:F222	8.8775	4	3	8
97	B:B:H225	9.00667	6	3	9
98	B:B:D228	9.5675	4	1	9
99	B:B:I232	5.4775	4	3	8
100	B:B:F235	6.618	5	20	6
101	B:B:P236	6.015	4	20	7
102	B:B:N237	6.4875	4	0	5
103	B:B:F241	7.466	5	3	6
104	B:B:T243	5.5575	4	3	8
105	B:B:D247	7.702	5	3	9
106	B:B:R251	10.954	5	3	8
107	B:B:F253	7.67	5	3	6
108	B:B:D258	8.5425	4	3	7
109	B:B:Q259	4.5	4	0	6
110	B:B:E260	7.705	4	3	6
111	B:B:M262	6.845	4	0	4
112	B:B:Y264	6.665	6	0	5
113	B:B:F278	7.5975	4	20	7
114	B:B:R283	7.864	5	16	9
115	B:B:Y289	7.06286	7	5	7
116	B:B:D290	6.274	5	5	6
117	B:B:N295	9.5675	4	5	6
118	B:B:H311	8.034	5	9	9
119	B:B:R314	13.198	5	5	8
120	B:B:V315	4.176	5	9	7
121	B:B:M325	5.7225	4	8	5
122	B:B:T329	5.306	5	9	8
123	B:B:W332	11.855	6	5	9
124	B:B:D333	9.7625	4	9	9
125	B:B:K337	7.1225	4	9	6
126	B:B:W339	7.852	5	9	9
127	G:G:R27	6.24	4	3	8
128	G:G:D48	5.5	5	0	9
129	G:G:L51	4.066	5	0	6
130	G:G:N59	7.742	5	8	9
131	G:G:P60	7.1725	4	8	9
132	G:G:F61	5.485	8	8	8
133	R:R:Y195	3.9475	4	0	7
134	R:R:F212	8.0025	4	6	7
135	R:R:L215	7.6525	4	6	9
136	R:R:R219	6.282	5	6	9
137	R:R:H223	7.735	4	6	9
138	R:R:M224	3.5525	4	0	5
139	R:R:F230	6.12833	6	0	8
140	R:R:R233	7.625	6	14	8
141	R:R:I237	4.4675	4	14	7
142	R:R:Y290	6.9525	4	19	9
143	R:R:Y296	5.6375	4	14	7
144	R:R:Y297	5.59	4	21	6
145	R:R:W298	12.3875	4	19	9
146	R:R:E302	9.945	4	6	9
147	R:R:F311	5.375	4	0	6
148	R:R:F314	7.3175	4	10	7
149	R:R:W329	9.27	5	19	9
150	R:R:W339	4.415	4	0	8
151	R:R:I367	5.175	4	14	7
152	R:R:F378	4.525	4	0	9
153	R:R:K388	6.274	5	11	9
154	R:R:T392	4.8075	4	11	7
155	R:R:Y421	6.97	4	14	8
156	R:R:F453	7.7875	4	0	6
157	R:R:E465	6.58	4	6	9
158	R:R:E469	9.5225	4	6	9
159	W:W:?1	9.07667	12	6	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:W281	B:B:W332	89.9791	4.69	Yes	Yes	5	5	9
2	A:A:R280	A:A:W281	90.0501	22.99	No	Yes	5	5	5
3	A:A:R280	A:A:R283	99.8096	5.33	No	No	0	5	3
4	A:A:R283	A:A:R356	99.8478	12.79	No	Yes	0	3	2
5	A:A:H357	A:A:R356	99.8912	9.03	No	Yes	2	7	2
6	A:A:H357	A:A:W277	100	29.62	No	Yes	2	7	6
7	A:A:F273	A:A:W277	59.5503	5.01	Yes	Yes	2	9	6
8	A:A:F273	A:A:F345	39.8304	5.36	Yes	Yes	0	9	8
9	A:A:F345	A:A:L270	20.0276	9.74	Yes	No	0	8	6
10	A:A:E344	A:A:L270	19.9697	3.98	Yes	No	0	5	6
11	A:A:E344	A:A:F312	19.5963	3.5	Yes	Yes	13	5	8
12	A:A:F312	A:A:I308	19.5949	3.77	Yes	No	0	8	7
13	A:A:I308	A:A:Y253	19.7958	12.09	No	Yes	0	7	8
14	A:A:K300	A:A:Y253	97.2759	17.91	Yes	Yes	2	9	8
15	A:A:K300	A:A:S251	96.8302	6.12	Yes	No	0	9	9
16	A:A:L296	A:A:S251	96.677	3	Yes	No	0	6	9
17	A:A:K293	A:A:L296	95.9104	4.23	No	Yes	0	9	6
18	A:A:K293	A:A:N292	94.3737	8.39	No	No	0	9	9
19	A:A:F345	A:A:L289	19.797	7.31	Yes	Yes	0	8	9
20	A:A:L289	A:A:L291	59.209	6.92	Yes	No	0	9	8
21	A:A:L291	A:A:S250	59.1201	4.5	No	No	0	8	6
22	A:A:L297	A:A:S250	59.0343	3	Yes	No	2	8	6
23	A:A:L297	A:A:Y253	77.8131	3.52	Yes	Yes	2	8	8
24	A:A:C359	A:A:F273	19.7833	4.19	No	Yes	2	5	9
25	A:A:C359	A:A:L289	39.4863	3.17	No	Yes	0	5	9
26	A:A:S349	A:A:W277	40.5689	11.12	Yes	Yes	2	7	6
27	A:A:C359	A:A:S349	19.7546	5.16	No	Yes	2	5	7
28	A:A:L346	A:A:S349	20.8131	3	No	Yes	2	4	7
29	A:A:L346	A:A:R342	20.7617	4.86	No	Yes	2	4	4
30	A:A:F363	A:A:R342	19.9639	8.55	Yes	Yes	2	5	4
31	A:A:F363	A:A:Q294	19.7411	10.54	Yes	Yes	2	5	6
32	A:A:L297	A:A:Q294	19.8475	5.32	Yes	Yes	2	8	6
33	A:A:N292	A:A:T364	88.0859	4.39	No	No	0	9	9
34	A:A:K233	B:B:Y145	59.0683	3.58	Yes	Yes	1	9	8
35	A:A:K233	B:B:D228	29.3031	8.3	Yes	Yes	1	9	9
36	A:A:K233	B:B:D246	29.1461	4.15	Yes	No	1	9	9
37	A:A:C237	B:B:Q75	42.7346	4.58	No	Yes	0	8	9
38	A:A:C237	B:B:M101	42.6684	4.86	No	Yes	0	8	9
39	B:B:Q75	B:B:Y59	42.7346	3.38	Yes	No	0	9	8
40	B:B:M101	B:B:Y59	42.6684	10.78	Yes	No	0	9	8
41	B:B:K57	B:B:W332	90.6076	17.4	Yes	Yes	5	9	9
42	B:B:K57	B:B:Q75	90.5342	13.56	Yes	Yes	0	9	9
43	A:A:F290	A:A:I288	43.3188	3.77	Yes	No	0	9	9
44	A:A:F290	A:A:T364	86.9236	6.49	Yes	No	23	9	9
45	A:A:D378	A:A:I288	42.9964	9.8	No	No	0	7	9
46	A:A:D378	A:A:Y360	85.6826	17.24	No	No	0	7	8
47	A:A:F290	A:A:H362	43.3186	6.79	Yes	No	0	9	9
48	A:A:D378	A:A:H362	43.015	8.82	No	No	0	7	9
49	A:A:D381	A:A:Y360	84.6974	13.79	No	No	0	8	8
50	A:A:D381	R:R:K388	74.6512	6.91	No	Yes	11	8	9
51	A:A:Q384	R:R:K388	71.3996	9.49	No	Yes	0	6	9
52	A:A:Q384	R:R:I310	71.0564	4.12	No	No	0	6	8
53	R:R:I310	R:R:L306	70.7505	4.28	No	No	0	8	9
54	A:A:Y391	R:R:L306	69.7495	9.38	Yes	No	0	4	9
55	A:A:Y391	W:W:?1	60.7321	4.92	Yes	Yes	6	4	0
56	R:R:I299	W:W:?1	13.2359	8.98	No	Yes	0	9	0
57	R:R:F230	R:R:I299	12.8985	3.77	Yes	No	0	8	9
58	R:R:F230	R:R:N295	19.7226	6.04	Yes	No	0	8	8
59	R:R:N295	R:R:S229	19.0673	8.94	No	No	0	8	9
60	R:R:S229	R:R:T294	18.387	4.8	No	No	0	9	8
61	R:R:T294	R:R:W329	14.3015	4.85	No	Yes	19	8	9
62	R:R:F417	W:W:?1	34.9646	12.77	No	Yes	0	9	0
63	R:R:F230	R:R:F417	12.9004	4.29	Yes	No	0	8	9
64	B:B:D228	B:B:S227	29.741	4.42	Yes	No	0	9	6
65	B:B:D247	B:B:S227	58.414	4.42	Yes	No	0	9	6
66	B:B:D247	B:B:H225	38.8383	5.04	Yes	Yes	3	9	9
67	B:B:H225	B:B:T243	19.9111	6.85	Yes	Yes	3	9	8
68	B:B:F253	B:B:T243	16.0016	7.78	Yes	Yes	3	6	8
69	B:B:F222	B:B:F253	45.0655	10.72	Yes	Yes	3	8	6
70	B:B:D258	B:B:F222	35.2787	5.97	Yes	Yes	3	7	8
71	B:B:D258	B:B:R22	31.3655	9.53	Yes	Yes	3	7	6
72	B:B:I18	B:B:R22	25.4905	7.52	No	Yes	0	7	6
73	B:B:I18	G:G:L19	19.6109	1.43	No	No	0	7	9
74	B:B:A11	G:G:L19	17.6506	1.58	No	No	0	5	9
75	B:B:A11	G:G:V16	15.6902	1.7	No	No	0	5	7
76	B:B:E10	G:G:V16	13.7296	2.85	No	No	0	8	7
77	B:B:E10	B:B:L7	11.7688	3.98	No	Yes	0	8	8
78	B:B:D246	B:B:S227	28.9953	5.89	No	No	0	9	6
79	B:B:H225	B:B:R251	17.6305	14.67	Yes	Yes	3	9	8
80	B:B:F253	B:B:R251	31.9983	4.28	Yes	Yes	3	6	8
81	B:B:D247	B:B:T249	18.6055	7.23	Yes	No	0	9	6
82	B:B:R251	B:B:T249	17.6292	9.06	Yes	No	0	8	6
83	B:B:G162	B:B:Y145	27.8189	10.14	No	Yes	1	9	8
84	B:B:G162	B:B:S161	28.3919	3.71	No	No	1	9	9
85	B:B:H142	B:B:S161	27.2055	15.34	Yes	No	1	9	9
86	B:B:H142	B:B:T159	11.5734	6.85	Yes	Yes	1	9	9
87	B:B:H142	B:B:W169	15.488	4.23	Yes	Yes	1	9	8
88	B:B:L139	B:B:W169	14.4818	12.53	No	Yes	0	9	8
89	B:B:I123	B:B:L139	14.3134	4.28	Yes	No	0	6	9
90	B:B:I123	B:B:Y111	11.4313	3.63	Yes	Yes	1	6	4
91	B:B:C271	B:B:D290	12.0217	3.11	No	Yes	5	5	6
92	B:B:C271	B:B:Y289	11.3802	4.03	No	Yes	5	5	7
93	R:R:F417	R:R:Q451	21.7338	4.68	No	No	0	9	9
94	R:R:Q451	R:R:R233	17.6784	17.52	No	Yes	0	9	8
95	R:R:R233	R:R:Y296	12.2835	5.14	Yes	Yes	14	8	7
96	B:B:M101	B:B:Y145	85.0467	8.38	Yes	Yes	0	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:L393	A:A:Y391	5.86	0	No	Yes	8	4	2	1
A:A:Y391	R:R:R219	7.2	6	Yes	Yes	4	9	1	1
A:A:Y391	R:R:L306	9.38	6	Yes	No	4	9	1	2
A:A:Y391	W:W:?1	4.92	6	Yes	Yes	4	0	1	0
A:A:E392	R:R:G464	4.91	0	No	No	6	7	1	2
A:A:E392	W:W:?1	5.56	0	No	Yes	6	0	1	0
R:R:N220	R:R:R219	9.64	6	No	Yes	9	9	2	1
R:R:H223	R:R:R219	7.9	6	Yes	Yes	9	9	1	1
R:R:E465	R:R:R219	3.49	6	Yes	Yes	9	9	2	1
R:R:R219	W:W:?1	3.18	6	Yes	Yes	9	0	1	0
R:R:H223	R:R:N220	5.1	6	Yes	No	9	9	1	2
R:R:E302	R:R:I222	6.83	6	Yes	No	9	9	1	2
R:R:E302	R:R:H223	9.85	6	Yes	Yes	9	9	1	1
R:R:H223	W:W:?1	8.09	6	Yes	Yes	9	0	1	0
R:R:F230	R:R:L226	9.74	0	Yes	No	8	9	2	2
R:R:E302	R:R:L226	10.6	6	Yes	No	9	9	1	2
R:R:F230	R:R:I299	3.77	0	Yes	No	8	9	2	1
R:R:F230	R:R:F417	4.29	0	Yes	No	8	9	2	1
R:R:F230	R:R:V455	10.49	0	Yes	No	8	9	2	2
R:R:I299	W:W:?1	8.98	0	No	Yes	9	0	1	0
R:R:E302	W:W:?1	12.5	6	Yes	Yes	9	0	1	0
R:R:L416	R:R:M414	7.07	0	No	No	9	8	1	2
R:R:L416	W:W:?1	7.25	0	No	Yes	9	0	1	0
R:R:F417	R:R:Q451	4.68	0	No	No	9	9	1	2
R:R:F417	W:W:?1	12.77	0	No	Yes	9	0	1	0
R:R:F454	R:R:I458	5.02	0	No	No	6	8	1	2
R:R:F454	W:W:?1	8.94	0	No	Yes	6	0	1	0
R:R:V455	R:R:Y459	3.79	0	No	No	9	8	2	1
R:R:Y459	W:W:?1	25.81	0	No	Yes	8	0	1	0
R:R:E465	R:R:N463	13.15	6	Yes	No	9	9	2	1
R:R:N463	R:R:V466	5.91	6	No	No	9	9	1	2
R:R:N463	W:W:?1	9.36	6	No	Yes	9	0	1	0
R:R:E465	R:R:V466	5.7	6	Yes	No	9	9	2	2
R:R:L416	R:R:V419	2.98	0	No	No	9	7	1	2
R:R:V412	W:W:?1	1.56	0	No	Yes	8	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
76.92	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
26.32	Single	8FN0	PubChem 118610427	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
25.00	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
25.00	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
23.53	Consensus	nts1_on_allo	Other Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
21.43	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
21.05	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
21.05	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
20.00	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
18.18	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
18.18	Consensus	ccr9_off_allo	Other Ligand	5LWE-CCR9-Vercirnon
15.00	Single	6QZH	HY-133073; Na	6QZH-CCR7-HY-133073; Na
15.00	Consensus	ccr7_off_allo	Other Ligand	6QZH-CCR7-HY-133073; Na
14.29	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
14.29	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
14.29	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
13.04	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
12.50	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
11.54	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
11.11	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
11.11	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
11.11	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
10.53	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
10.53	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
10.53	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
10.00	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
10.00	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
9.52	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
9.52	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
9.09	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
9.09	Consensus	ffa3_on_allo	Other Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
8.70	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
8.70	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
8.33	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
8.33	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
7.69	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
7.69	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
6.67	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
5.88	Single	7EB2	rac-BHFF	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.88	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
5.88	Consensus	gabab_on	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.88	Consensus	gi_class-c	Other Ligand	gi_mglu gi_gaba
5.56	Consensus	gi_gaba	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.26	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
5.26	Single	7LD3	PubChem 25263603	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
5.26	Consensus	a1_on_allo	Other Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
5.00	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
5.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
5.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
5.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.00	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
5.00	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
5.00	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
5.00	Single	8HNN	SCH546738	8HNN-CXCR3-SCH546738
5.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
5.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.00	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.76	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
4.76	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
4.76	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
4.76	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
4.76	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
4.55	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
4.55	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
4.55	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
4.55	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
4.55	Single	7RBT	PubChem 163183774	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
4.55	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
4.55	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.35	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
4.35	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
4.35	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
4.35	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
4.35	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
4.35	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.17	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
4.17	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
4.17	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.17	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.17	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
4.00	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
4.00	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.00	Consensus	gi_class-f	Other Ligand	gi_frizzled
4.00	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
3.45	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
3.03	Single	3VG9	Antibody	3VG9-A_2A-ZM241385-Antibody
2.86	Single	3VGA	Antibody	3VGA-A_2A-ZM241385-Antibody
2.78	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
2.78	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
2.78	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
2.63	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
2.63	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.56	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
2.27	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
2.27	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.17	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2

PDB Summary
PDB	8GW8
Class	B1
SubFamily	Peptide
Type	Parathyroid hormone
SubType	PTH1
Species	Homo sapiens
Ligand	-
Other Ligand(s)	KHF
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	2.9
Date	2023-06-14
D.O.I.	10.1038/s41586-023-06169-3

Net Summary
I_min	3
Number of Linked Nodes	798
Number of Links	979
Number of Hubs	159
Number of Links mediated by Hubs	581
Number of Communities	28
Number of Nodes involved in Communities	232
Number of Links involved in Communities	328

Path Summary
Number Of Nodes in MetaPath	97
Number Of Links MetaPath	96
Number of Shortest Paths	4959017
Length Of Smallest Path	3
Average Path Length	44.2167
Length of Longest Path	72
Minimum Path Strength	1.17
Average Path Strength	7.99435
Maximum Path Strength	23.49
Minimum Path Correlation	0.7
Average Path Correlation	0.991419
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.12766
Average % Of Corr. Nodes	27.0678
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.1413
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	KHF
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	KHF
Name	PCO-371
Synonyms	1-[3,5-dimethyl-4-[2-[[4-oxidanylidene-2-[4-(trifluoromethyloxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-5,5-dimethyl-imidazolidine-2,4-dione
Identifier	1-[3,5-dimethyl-4-[2-[[4-oxidanylidene-2-[4-(trifluoromethyloxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-5,5-dimethyl-imidazolidine-2,4-dione
Formula	C29 H32 F3 N5 O6 S
Molecular Weight	635.654
SMILES	Cc1cc(cc(c1CCS(=O)(=O)N2CCC3(CC2)C(=O)NC(=N3)c4ccc(cc4)OC(F)(F)F)C)N5C(=O)NC(=O)C5(C)C
PubChem	76283707
Formal Charge	0
Total Atoms	76
Total Chiral Atoms	0
Total Bonds	80
Total Aromatic Bonds	12


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8GW8_Chain_A Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I V K Q M R I G I F E T K F Q V D K V N F H M F D V G G Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N L F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N A R R I F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8GW8_Chain_B Q S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8GW8_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q03431
Sequence	>8GW8_Chain_R Y T V G Y S V S L A S L T V A V L I L A Y F R R L H C T R N Y I H M H L F L S F M L R A V S I F V K D A V L Y S C R V A V T F F L Y F L A T N Y Y W I L V E G L Y L H S L I F M A F F S K Y L W G F T V F G W G L P A V F V A V W V S V R A T L K W I I Q V P I L A S I V L N F I L F I N I V R V L A T K L R E T N A G R C D T R Q Q Y R K L L K S T L V L M P L F G V H Y I V F M M L F N S F Q G F F V A I I Y C F C N G E V Q A E I K K S W S R W T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6FJ3	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	-	2.5	2018-11-21	10.1038/s41594-018-0151-4
	6NBF	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH analog	-	Gs/&β;1/&γ;2	3	2019-04-17	10.1126/science.aav7942
	6NBH	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH analog	-	Gs/&β;1/&γ;2	3.5	2019-04-17	10.1126/science.aav7942
	6NBI	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH analog	-	Gs/&β;1/&γ;2	4	2019-04-17	10.1126/science.aav7942
	7VVJ	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/&β;1/&γ;2	3.2	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVK	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	3.3	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVL	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	2.8	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVM	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	3.2	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVN	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	3.8	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVO	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	4.1	2022-08-03	10.1016/j.molcel.2022.07.003
	7Y35	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/&β;1/&γ;2	2.9	2023-07-05	To be published
	7Y36	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Teriparatide	-	Gs/&β;1/&γ;2	2.8	2023-07-05	To be published
	8FLQ	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	2.55	2023-04-26	10.1016/j.str.2023.04.002
	8FLR	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/&β;1/&γ;2	2.94	2023-04-26	10.1016/j.str.2023.04.002
	8FLS	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/&β;1/&γ;2	3.09	2023-04-26	10.1016/j.str.2023.04.002
	8FLT	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	M-PTH(1-14)	-	Gs/&β;1/&γ;2	3.03	2023-04-26	10.1016/j.str.2023.04.002
	8FLU	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH	-	Gs/&β;1/&γ;2	2.76	2023-04-26	10.1016/j.str.2023.04.002
	8GW8	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	-	KHF	Gs/&β;1/&γ;2	2.9	2023-06-14	10.1038/s41586-023-06169-3
	8HA0	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.62	2022-12-21	10.1038/s41401-022-01032-z
	8HAF	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.25	2022-12-21	10.1038/s41401-022-01032-z
	8HAO	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.76	2022-12-21	10.1038/s41401-022-01032-z
	8JR9	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	-	PCO371	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-08-02	10.1038/s41586-023-06467-w

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8GW8.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.