psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D208	R:R:R168	2.38	No	No	35	4	4
2	R:R:R168	R:R:Y209	6.17	No	Yes	35	4	8
3	R:R:E496	R:R:R168	13.96	No	No	0	4	4
4	R:R:A169	R:R:E210	3.02	No	No	0	3	5
5	R:R:K212	R:R:Y171	4.78	No	No	0	3	5
6	R:R:P237	R:R:Y171	16.69	Yes	No	16	6	5
7	R:R:K239	R:R:Y171	2.39	Yes	No	16	7	5
8	R:R:G173	R:R:I172	3.53	Yes	No	0	7	8
9	R:R:I172	R:R:I241	2.94	No	Yes	0	8	7
10	R:R:A174	R:R:G173	1.95	No	Yes	0	7	7
11	R:R:G173	R:R:I214	1.76	Yes	Yes	0	7	3
12	R:R:G173	R:R:L232	3.42	Yes	No	0	7	6
13	R:R:G173	R:R:L242	1.71	Yes	No	0	7	6
14	R:R:A174	R:R:F176	2.77	No	Yes	0	7	7
15	R:R:A174	R:R:M243	1.61	No	Yes	0	7	7
16	R:R:L175	R:R:P244	1.64	No	Yes	0	6	8
17	R:R:F176	R:R:P177	4.33	Yes	No	0	7	7
18	R:R:F176	R:R:Q189	4.68	Yes	No	0	7	4
19	R:R:F176	R:R:V192	2.62	Yes	No	0	7	7
20	R:R:F176	R:R:Y267	6.19	Yes	No	0	7	7
21	R:R:G185	R:R:P177	4.06	No	No	0	7	7
22	R:R:D217	R:R:M178	11.09	No	No	0	8	5
23	R:R:G180	R:R:S179	3.71	No	No	0	3	6
24	R:R:K219	R:R:S179	3.06	No	No	0	5	6
25	R:R:G180	R:R:G181	2.11	No	No	0	3	5
26	R:R:G181	R:R:Y367	4.35	No	No	0	5	7
27	R:R:G184	R:R:W182	2.81	No	Yes	0	5	6
28	R:R:G268	R:R:W182	2.81	Yes	Yes	0	7	6
29	R:R:W182	R:R:W395	14.06	Yes	No	0	6	5
30	R:R:E466	R:R:W182	7.63	No	Yes	0	5	6
31	R:R:G184	R:R:G185	2.11	No	No	0	5	7
32	R:R:G184	R:R:G463	2.11	No	No	0	5	4
33	R:R:C188	R:R:G185	3.92	No	No	0	5	7
34	R:R:A467	R:R:C188	3.61	No	No	0	7	5
35	R:R:P190	R:R:Q189	3.16	No	No	0	5	4
36	R:R:H215	R:R:Q189	9.89	No	No	0	2	4
37	R:R:P190	R:R:R453	2.88	No	No	0	5	1
38	R:R:A191	R:R:A467	1.79	No	No	0	8	7
39	R:R:A470	R:R:V192	3.39	No	No	0	7	7
40	R:R:E193	R:R:L213	3.98	No	No	0	4	6
41	R:R:K449	R:R:M194	11.52	No	No	0	5	7
42	R:R:M194	R:R:R453	8.69	No	No	0	7	1
43	R:R:A195	R:R:Y471	4	No	Yes	0	9	9
44	R:R:E197	R:R:R453	4.65	No	No	0	5	1
45	R:R:D198	R:R:Y471	4.6	No	Yes	5	7	9
46	R:R:D198	R:R:W475	7.82	No	Yes	5	7	8
47	R:R:N200	R:R:V199	4.43	No	No	0	9	7
48	R:R:I205	R:R:V199	7.68	Yes	No	0	6	7
49	R:R:V199	R:R:W475	4.9	No	Yes	0	7	8
50	R:R:E210	R:R:N200	9.2	No	No	0	5	9
51	R:R:R202	R:R:S201	2.64	Yes	No	0	5	4
52	R:R:D204	R:R:R202	16.68	No	Yes	5	4	5
53	R:R:I205	R:R:R202	8.77	Yes	Yes	5	6	5
54	R:R:R202	R:R:W475	2	Yes	Yes	5	5	8
55	R:R:D204	R:R:I205	7	No	Yes	5	4	6
56	R:R:A478	R:R:I205	1.62	No	Yes	0	9	6
57	R:R:L206	R:R:P207	4.93	No	No	0	9	3
58	R:R:L206	R:R:Y209	11.72	No	Yes	0	9	8
59	R:R:D208	R:R:P207	11.27	No	No	0	4	3
60	R:R:D208	R:R:Y209	3.45	No	Yes	35	4	8
61	R:R:L495	R:R:Y209	7.03	No	Yes	0	7	8
62	R:R:H215	R:R:L213	3.86	No	No	0	2	6
63	R:R:H216	R:R:I214	3.98	No	Yes	0	6	3
64	R:R:D236	R:R:I214	5.6	Yes	Yes	16	3	3
65	R:R:I214	R:R:P237	3.39	Yes	Yes	16	3	6
66	R:R:H216	R:R:Y228	15.24	No	No	0	6	5
67	R:R:D217	R:R:K219	6.91	No	No	0	8	5
68	R:R:K219	R:R:Q224	8.14	No	No	0	5	5
69	R:R:C220	R:R:C246	7.28	No	No	6	8	7
70	R:R:C220	R:R:S248	1.72	No	Yes	6	8	5
71	R:R:D221	R:R:P222	4.83	Yes	No	6	6	6
72	R:R:D221	R:R:G223	1.68	Yes	Yes	6	6	7
73	R:R:D221	R:R:Q224	7.83	Yes	No	0	6	5
74	R:R:D221	S:S:E144	7.8	Yes	No	6	6	7
75	R:R:P222	R:R:S248	1.78	No	Yes	6	6	5
76	R:R:P222	S:S:E144	14.15	No	No	6	6	7
77	R:R:G223	R:R:T226	3.64	Yes	No	6	7	7
78	R:R:G223	S:S:E144	6.55	Yes	No	6	7	7
79	R:R:G223	S:S:S145	3.71	Yes	No	6	7	7
80	R:R:T226	S:S:Y118	3.75	No	Yes	0	7	7
81	R:R:T226	S:S:S145	9.59	No	No	6	7	7
82	R:R:E231	R:R:K227	4.05	No	No	0	6	7
83	R:R:K227	S:S:W149	8.12	No	No	0	7	7
84	R:R:L229	S:S:Y118	2.34	No	Yes	0	7	7
85	R:R:Y230	R:R:Y234	5.96	Yes	Yes	11	7	5
86	R:R:Y230	S:S:Y118	6.95	Yes	Yes	0	7	7
87	R:R:Y230	S:S:I121	3.63	Yes	No	0	7	6
88	R:R:Y230	S:S:K122	7.17	Yes	Yes	11	7	4
89	R:R:Y230	S:S:W149	3.86	Yes	No	0	7	7
90	R:R:D236	R:R:L232	10.86	Yes	No	16	3	6
91	R:R:K239	R:R:L232	5.64	Yes	No	16	7	6
92	R:R:L233	R:R:Y234	2.34	No	Yes	11	7	5
93	R:R:L233	R:R:W260	5.69	No	Yes	11	7	7
94	R:R:L233	R:R:Y500	5.86	No	Yes	11	7	8
95	R:R:W260	R:R:Y234	7.72	Yes	Yes	11	7	5
96	R:R:Y234	S:S:K122	3.58	Yes	Yes	11	5	4
97	R:R:N235	S:S:K122	5.6	No	Yes	0	3	4
98	R:R:D236	R:R:P237	9.66	Yes	Yes	16	3	6
99	R:R:D236	R:R:K239	8.3	Yes	Yes	16	3	7
100	R:R:K239	R:R:P237	11.71	Yes	Yes	16	7	6
101	R:R:F498	R:R:I238	2.51	No	No	0	8	5
102	R:R:I240	R:R:I241	5.89	No	Yes	0	5	7
103	R:R:F498	R:R:I240	8.79	No	No	0	8	5
104	R:R:I241	R:R:I263	4.42	Yes	No	0	7	6
105	R:R:I241	R:R:L477	2.85	Yes	No	0	7	5
106	R:R:L242	R:R:P244	1.64	No	Yes	0	6	8
107	R:R:M243	R:R:P244	1.68	Yes	Yes	0	7	8
108	R:R:L265	R:R:M243	5.65	No	Yes	0	6	7
109	R:R:M243	R:R:Y267	4.79	Yes	No	0	7	7
110	R:R:G245	R:R:P244	2.03	No	Yes	0	6	8
111	R:R:P244	R:R:V264	3.53	Yes	No	0	8	9
112	R:R:P244	R:R:S266	1.78	Yes	Yes	0	8	8
113	R:R:G245	R:R:Y267	4.35	No	No	0	6	7
114	R:R:C246	R:R:S248	1.72	No	Yes	6	7	5
115	R:R:C246	R:R:V249	3.42	No	No	6	7	8
116	R:R:S247	R:R:S269	6.52	No	Yes	4	9	8
117	R:R:S247	R:R:S271	3.26	No	Yes	4	9	9
118	R:R:S247	R:R:V318	4.85	No	Yes	4	9	5
119	R:R:S248	R:R:V249	3.23	Yes	No	6	5	8
120	R:R:S250	R:R:T251	1.6	No	Yes	0	8	7
121	R:R:S250	R:R:S269	4.89	No	Yes	0	8	8
122	R:R:F283	R:R:S250	3.96	Yes	No	0	8	8
123	R:R:S271	R:R:T251	3.2	Yes	Yes	4	9	7
124	R:R:L274	R:R:T251	2.95	Yes	Yes	4	8	7
125	R:R:E317	R:R:T251	2.82	No	Yes	0	6	7
126	R:R:A254	R:R:F280	4.16	No	Yes	0	8	8
127	R:R:E255	R:R:R279	4.65	No	Yes	4	8	6
128	R:R:E255	R:R:F280	8.16	No	Yes	4	8	8
129	R:R:E255	S:S:N110	5.26	No	Yes	0	8	5
130	R:R:A257	R:R:T282	1.68	No	No	0	7	8
131	R:R:M259	R:R:R258	2.48	Yes	No	0	5	5
132	R:R:R258	S:S:D109	5.96	No	No	0	5	5
133	R:R:M259	R:R:W260	2.33	Yes	Yes	11	5	7
134	R:R:M259	S:S:A111	1.61	Yes	No	0	5	7
135	R:R:M259	S:S:K115	7.2	Yes	No	11	5	6
136	R:R:L262	R:R:W260	2.28	No	Yes	11	7	7
137	R:R:W260	R:R:Y500	12.54	Yes	Yes	11	7	8
138	R:R:W260	S:S:K115	2.32	Yes	No	11	7	6
139	R:R:N261	R:R:Q503	11.88	No	Yes	14	8	3
140	R:R:N261	R:R:T506	5.85	No	No	14	8	5
141	R:R:L262	R:R:Y500	2.34	No	Yes	11	7	8
142	R:R:I263	R:R:T282	4.56	No	No	0	6	8
143	R:R:F284	R:R:I263	3.77	Yes	No	0	6	6
144	R:R:F283	R:R:V264	5.24	Yes	No	0	8	9
145	R:R:F284	R:R:L265	2.44	Yes	No	0	6	6
146	R:R:G268	R:R:S266	1.86	Yes	Yes	4	7	8
147	R:R:S266	R:R:S269	3.26	Yes	Yes	4	8	8
148	R:R:F283	R:R:S266	2.64	Yes	Yes	4	8	8
149	R:R:G268	R:R:S269	1.86	Yes	Yes	4	7	8
150	R:R:G268	R:R:H287	4.77	Yes	No	0	7	7
151	R:R:A290	R:R:S270	3.42	No	No	0	8	7
152	R:R:P272	R:R:S271	1.78	No	Yes	0	7	9
153	R:R:L274	R:R:S271	3	Yes	Yes	4	8	9
154	R:R:S271	R:R:V318	8.08	Yes	Yes	4	9	5
155	R:R:P272	R:R:S321	1.78	No	No	0	7	6
156	R:R:P272	R:R:T322	5.25	No	No	0	7	7
157	R:R:A273	R:R:S321	1.71	No	No	0	6	6
158	R:R:F280	R:R:L274	7.31	Yes	Yes	4	8	8
159	R:R:F283	R:R:L274	8.53	Yes	Yes	4	8	8
160	R:R:L274	R:R:R285	3.64	Yes	Yes	4	8	9
161	R:R:R285	R:R:S275	2.64	Yes	No	0	9	8
162	R:R:A529	R:R:S275	1.71	No	No	0	4	8
163	R:R:N276	R:R:Q278	3.96	No	No	0	7	3
164	R:R:N276	R:R:R279	4.82	No	Yes	0	7	6
165	R:R:F284	R:R:R277	2.14	Yes	No	24	6	7
166	R:R:R277	R:R:Y510	2.06	No	No	24	7	5
167	R:R:F280	R:R:R279	22.45	Yes	Yes	4	8	6
168	R:R:E317	R:R:R279	4.65	No	Yes	0	6	6
169	R:R:P281	R:R:T282	6.99	No	No	0	7	8
170	R:R:F283	R:R:R285	3.21	Yes	Yes	4	8	9
171	R:R:F284	R:R:Y510	5.16	Yes	No	24	6	5
172	R:R:F284	R:R:M513	11.2	Yes	No	24	6	6
173	R:R:F284	R:R:F527	6.43	Yes	No	24	6	9
174	R:R:R285	R:R:S289	6.59	Yes	No	0	9	8
175	R:R:L469	R:R:T286	8.84	No	No	0	6	7
176	R:R:R533	R:R:T286	5.17	Yes	No	0	9	7
177	R:R:H287	R:R:P288	9.15	No	No	0	7	6
178	R:R:I427	R:R:P288	1.69	No	No	36	5	6
179	R:R:M429	R:R:P288	1.68	No	No	36	4	6
180	R:R:S289	R:R:T291	1.6	No	No	0	8	6
181	R:R:G531	R:R:S289	1.86	No	No	0	8	8
182	R:R:A290	R:R:H293	4.39	No	Yes	0	8	5
183	R:R:D325	R:R:T291	5.78	No	No	0	6	6
184	R:R:H293	R:R:R297	4.51	Yes	Yes	0	5	7
185	R:R:H293	R:R:T425	4.11	Yes	No	0	5	6
186	R:R:H293	R:R:I427	6.63	Yes	No	0	5	5
187	R:R:N294	R:R:P295	3.26	No	No	0	9	3
188	R:R:N294	R:R:R297	4.82	No	Yes	0	9	7
189	R:R:L326	R:R:N294	12.36	No	No	0	8	9
190	R:R:P295	R:R:R329	4.32	No	No	0	3	4
191	R:R:T296	R:R:T537	4.71	No	No	25	8	6
192	R:R:T296	R:R:Y553	2.5	No	Yes	25	8	6
193	R:R:F301	R:R:R297	3.21	No	Yes	12	6	7
194	R:R:F391	R:R:R297	3.21	Yes	Yes	12	7	7
195	R:R:V298	R:R:V330	1.6	No	No	0	6	7
196	R:R:K299	R:R:Y553	9.55	No	Yes	25	6	6
197	R:R:D558	R:R:K299	8.3	No	No	25	4	6
198	R:R:L300	R:R:W304	3.42	No	Yes	0	6	7
199	R:R:F301	R:R:W306	3.01	No	Yes	12	6	9
200	R:R:F301	R:R:F391	10.72	No	Yes	12	6	7
201	R:R:K303	R:R:W304	12.76	No	Yes	0	4	7
202	R:R:K303	R:R:W562	10.44	No	Yes	0	4	5
203	R:R:W304	R:R:W306	5.62	Yes	Yes	12	7	9
204	R:R:W304	R:R:W568	10.31	Yes	Yes	12	7	9
205	R:R:P573	R:R:W304	13.51	Yes	Yes	12	5	7
206	R:R:I361	R:R:W306	9.4	No	Yes	12	9	9
207	R:R:V389	R:R:W306	2.45	No	Yes	12	8	9
208	R:R:F391	R:R:W306	2	Yes	Yes	12	7	9
209	R:R:A575	R:R:W306	2.59	No	Yes	0	4	9
210	R:R:D576	R:R:W306	3.35	No	Yes	0	9	9
211	R:R:I335	R:R:K307	2.91	No	No	0	7	5
212	R:R:K308	R:R:Q577	12.2	No	No	0	7	5
213	R:R:I309	R:R:I337	4.42	No	No	0	8	6
214	R:R:I309	R:R:I361	5.89	No	No	0	8	9
215	R:R:A310	R:R:F339	2.77	No	Yes	0	8	6
216	R:R:L323	R:R:T311	5.9	No	No	0	6	7
217	R:R:R340	R:R:T311	3.88	Yes	No	0	6	7
218	R:R:T311	R:R:V363	1.59	No	No	0	7	7
219	R:R:I312	R:R:Q341	4.12	No	Yes	0	6	7
220	R:R:Q313	R:R:T320	5.67	Yes	No	0	7	7
221	R:R:L323	R:R:Q313	5.32	No	Yes	0	6	7
222	R:R:Q313	R:R:S342	4.33	Yes	No	18	7	7
223	R:R:Q313	S:S:D204	3.92	Yes	No	18	7	6
224	R:R:Q314	R:R:T316	9.92	No	No	0	8	5
225	R:R:F343	R:R:Q314	2.34	No	No	0	7	8
226	R:R:T315	S:S:Q206	12.76	No	No	0	6	6
227	R:R:T316	R:R:V318	4.76	No	Yes	0	5	5
228	R:R:F319	R:R:V318	15.73	No	Yes	0	7	5
229	R:R:F319	R:R:Y367	5.16	No	No	0	7	7
230	R:R:S321	R:R:T320	1.6	No	No	0	6	7
231	R:R:D325	R:R:E328	5.2	No	No	37	6	4
232	R:R:D325	R:R:R329	3.57	No	No	37	6	4
233	R:R:E327	R:R:I337	4.1	No	No	18	5	6
234	R:R:E327	R:R:R340	3.49	No	Yes	18	5	6
235	R:R:E328	R:R:R329	11.63	No	No	37	4	4
236	R:R:I335	R:R:V330	7.68	No	No	0	7	7
237	R:R:A333	R:R:E332	6.03	No	No	0	5	3
238	R:R:I337	R:R:R340	3.76	No	Yes	18	6	6
239	R:R:F339	R:R:Q341	10.54	Yes	Yes	19	6	7
240	R:R:F339	R:R:N353	4.83	Yes	No	19	6	6
241	R:R:F339	R:R:Q357	7.03	Yes	No	0	6	6
242	R:R:R340	S:S:D204	9.53	Yes	No	18	6	6
243	R:R:R340	S:S:S233	7.91	Yes	No	0	6	4
244	R:R:P350	R:R:Q341	7.9	Yes	Yes	19	7	7
245	R:R:N353	R:R:Q341	3.96	No	Yes	19	6	7
246	R:R:S342	S:S:D204	5.89	No	No	18	7	6
247	R:R:S342	S:S:S209	6.52	No	No	0	7	6
248	R:R:F343	R:R:P347	5.78	No	No	0	7	6
249	R:R:F344	S:S:V162	6.55	Yes	No	38	4	6
250	R:R:F344	S:S:K168	3.72	Yes	No	0	4	5
251	R:R:F344	S:S:Q206	2.34	Yes	No	38	4	6
252	R:R:F344	S:S:E210	3.5	Yes	No	0	4	6
253	R:R:D346	R:R:P347	3.22	No	No	0	6	6
254	R:R:P347	R:R:V374	1.77	No	No	0	6	7
255	R:R:A348	R:R:V349	1.7	No	Yes	0	3	3
256	R:R:A348	R:R:E377	4.53	No	No	0	3	7
257	R:R:P350	R:R:V349	3.53	Yes	Yes	19	7	3
258	R:R:V349	S:S:N213	5.91	Yes	No	19	3	6
259	R:R:V349	S:S:T216	3.17	Yes	No	0	3	5
260	R:R:P350	R:R:V351	1.77	Yes	No	0	7	8
261	R:R:P350	S:S:N213	8.15	Yes	No	19	7	6
262	R:R:V351	R:R:V378	1.6	No	Yes	0	8	8
263	R:R:E381	R:R:K352	9.45	No	No	0	5	4
264	R:R:N353	S:S:T229	11.7	No	No	0	6	6
265	R:R:K355	R:R:L383	4.23	No	Yes	7	8	7
266	R:R:K355	R:R:Y388	2.39	No	No	7	8	8
267	R:R:K387	R:R:R360	13.61	Yes	No	7	6	9
268	R:R:R360	R:R:T578	5.17	No	Yes	7	9	6
269	R:R:D751	R:R:R360	9.53	No	No	7	8	9
270	R:R:I361	R:R:V389	3.07	No	No	12	9	8
271	R:R:I362	R:R:W390	18.79	No	No	0	9	9
272	R:R:G364	R:R:V363	3.68	No	No	0	6	7
273	R:R:G364	R:R:L365	1.71	No	No	0	6	6
274	R:R:F366	R:R:G364	3.01	No	No	0	8	6
275	R:R:I393	R:R:L365	2.85	Yes	No	0	5	6
276	R:R:A371	R:R:F366	4.16	No	No	0	8	8
277	R:R:F366	R:R:Y396	2.06	No	Yes	0	8	5
278	R:R:E368	R:R:T369	5.64	No	No	3	7	3
279	R:R:E368	R:R:R372	16.28	No	Yes	3	7	7
280	R:R:E368	R:R:Y396	3.37	No	Yes	0	7	5
281	R:R:R372	R:R:T369	3.88	Yes	No	3	7	3
282	R:R:A371	R:R:W400	3.89	No	Yes	0	8	8
283	R:R:R372	R:R:W400	2	Yes	Yes	0	7	8
284	R:R:D405	R:R:R372	5.96	Yes	Yes	3	3	7
285	R:R:V374	R:R:V378	1.6	No	Yes	0	7	8
286	R:R:F375	R:R:V378	3.93	Yes	Yes	7	8	8
287	R:R:F375	R:R:W390	18.04	Yes	No	7	8	9
288	R:R:F375	R:R:L392	2.44	Yes	No	0	8	6
289	R:R:F375	R:R:W400	2	Yes	Yes	0	8	8
290	R:R:F375	R:R:V419	2.62	Yes	No	0	8	5
291	R:R:C376	R:R:I408	9.82	No	Yes	3	9	3
292	R:R:C376	R:R:C410	7.28	No	No	3	9	9
293	R:R:V378	R:R:W390	3.68	Yes	No	7	8	9
294	R:R:R382	R:R:Y379	14.4	No	Yes	3	5	7
295	R:R:F384	R:R:Y379	7.22	Yes	Yes	3	5	7
296	R:R:E414	R:R:Y379	22.45	Yes	Yes	3	7	7
297	R:R:E417	R:R:Y379	3.37	No	Yes	3	4	7
298	R:R:F384	R:R:R382	7.48	Yes	No	3	5	5
299	R:R:L383	R:R:Y388	9.38	Yes	No	7	7	8
300	R:R:F384	R:R:G385	3.01	Yes	No	0	5	9
301	R:R:A418	R:R:F384	6.93	No	Yes	0	9	5
302	R:R:I750	R:R:K386	2.91	No	No	0	4	5
303	R:R:K387	R:R:Y388	8.36	Yes	No	7	6	8
304	R:R:D751	R:R:K387	6.91	No	Yes	7	8	6
305	R:R:F391	R:R:V389	2.62	Yes	No	12	7	8
306	R:R:H422	R:R:L392	7.71	Yes	No	0	6	6
307	R:R:G394	R:R:I393	1.76	No	Yes	0	8	5
308	R:R:I393	R:R:W395	4.7	Yes	No	0	5	5
309	R:R:I393	R:R:Y396	6.04	Yes	Yes	0	5	5
310	R:R:G394	R:R:T424	3.64	No	No	0	8	6
311	R:R:E426	R:R:G394	4.91	No	No	0	6	8
312	R:R:W400	R:R:Y396	1.93	Yes	Yes	0	8	5
313	R:R:D398	R:R:Y547	2.3	No	Yes	0	4	5
314	R:R:K402	R:R:N399	4.2	No	No	0	2	4
315	R:R:I403	R:R:N399	7.08	No	No	0	1	4
316	R:R:F401	R:R:W400	18.04	No	Yes	0	7	8
317	R:R:W400	R:R:Y547	3.86	Yes	Yes	0	8	5
318	R:R:F401	R:R:K402	9.93	No	No	0	7	2
319	R:R:F401	R:R:M415	2.49	No	No	0	7	6
320	R:R:P406	R:R:Y404	9.74	No	No	0	3	1
321	R:R:D405	R:R:P406	4.83	Yes	No	3	3	3
322	R:R:D405	R:R:S407	4.42	Yes	No	3	3	1
323	R:R:D405	R:R:I408	18.19	Yes	Yes	3	3	3
324	R:R:P406	R:R:S407	3.56	No	No	3	3	1
325	R:R:C410	R:R:I408	3.27	No	Yes	3	9	3
326	R:R:C410	R:R:E414	3.04	No	Yes	3	9	7
327	R:R:T411	R:R:V412	1.59	No	No	0	6	1
328	R:R:E414	R:R:T411	8.47	Yes	No	0	7	6
329	R:R:T416	R:R:V412	3.17	No	No	0	2	1
330	R:R:D413	R:R:E417	3.9	No	No	0	5	4
331	R:R:E414	R:R:E417	2.54	Yes	No	3	7	4
332	R:R:H422	R:R:V419	5.54	Yes	No	0	6	5
333	R:R:E420	R:R:L542	5.3	No	No	0	6	4
334	R:R:E420	R:R:G544	4.91	No	No	0	6	4
335	R:R:H422	R:R:L542	10.29	Yes	No	26	6	4
336	R:R:H422	R:R:Y547	3.27	Yes	Yes	26	6	5
337	R:R:E540	R:R:T424	8.47	No	No	26	6	6
338	R:R:T424	R:R:Y547	2.5	No	Yes	26	6	5
339	R:R:E426	R:R:L538	6.63	No	No	0	6	4
340	R:R:I427	R:R:M429	4.37	No	No	36	5	4
341	R:R:L469	R:R:M429	2.83	No	No	0	6	4
342	R:R:L430	R:R:P432	3.28	No	No	0	3	4
343	R:R:N431	R:R:P432	6.52	No	No	0	6	4
344	R:R:A433	R:R:N431	3.13	No	No	0	3	6
345	R:R:G523	R:R:N431	1.7	No	No	0	9	6
346	R:R:A433	R:R:T435	1.68	No	No	0	3	3
347	R:R:N440	R:R:R436	20.49	No	No	0	7	1
348	R:R:S437	R:R:S439	4.89	No	Yes	5	7	8
349	R:R:M441	R:R:S437	4.6	Yes	No	5	5	7
350	R:R:I438	R:R:W475	2.35	No	Yes	0	5	8
351	R:R:M441	R:R:S439	3.07	Yes	Yes	5	5	8
352	R:R:S439	R:R:Y471	6.36	Yes	Yes	5	8	9
353	R:R:S439	R:R:W475	4.94	Yes	Yes	5	8	8
354	R:R:E445	R:R:M441	4.06	No	Yes	0	5	5
355	R:R:F446	R:R:M441	2.49	Yes	Yes	5	7	5
356	R:R:M441	R:R:Y471	2.39	Yes	Yes	5	5	9
357	R:R:S443	R:R:T442	3.2	No	No	39	4	8
358	R:R:Q444	R:R:T442	5.67	No	No	39	4	8
359	R:R:Q444	R:R:S443	7.22	No	No	39	4	4
360	R:R:F446	R:R:L450	7.31	Yes	No	0	7	7
361	R:R:F446	R:R:P468	4.33	Yes	Yes	0	7	5
362	R:R:F446	R:R:Y471	6.19	Yes	Yes	5	7	9
363	R:R:T451	R:R:V447	1.59	No	No	0	2	2
364	R:R:F464	R:R:V447	2.62	No	No	0	7	2
365	R:R:E448	R:R:T451	4.23	No	No	0	1	2
366	R:R:E448	R:R:K452	2.7	No	No	0	1	2
367	R:R:F464	R:R:L450	4.87	No	No	0	7	7
368	R:R:G462	R:R:G463	2.11	No	No	0	3	4
369	R:R:E466	R:R:G463	4.91	No	No	0	5	4
370	R:R:F464	R:R:Q465	2.34	No	No	0	7	4
371	R:R:E466	R:R:Q465	5.1	No	No	0	5	4
372	R:R:A467	R:R:P468	1.87	No	Yes	0	7	5
373	R:R:L469	R:R:P468	1.64	No	Yes	0	6	5
374	R:R:D472	R:R:P468	1.61	Yes	Yes	0	9	5
375	R:R:A470	R:R:I474	1.62	No	No	0	7	6
376	R:R:W475	R:R:Y471	17.36	Yes	Yes	5	8	9
377	R:R:V521	R:R:Y471	3.79	No	Yes	0	8	9
378	R:R:D472	R:R:G520	1.68	Yes	No	0	9	9
379	R:R:D472	R:R:V521	7.3	Yes	No	0	9	8
380	R:R:D472	R:R:S522	8.83	Yes	Yes	0	9	9
381	R:R:A473	R:R:I474	3.25	No	No	0	8	6
382	R:R:A476	R:R:F518	2.77	No	No	0	7	9
383	R:R:L477	R:R:L481	4.15	No	No	0	5	8
384	R:R:A480	R:R:I509	1.62	No	No	0	8	6
385	R:R:K483	R:R:S515	3.06	No	No	0	4	5
386	R:R:S485	R:R:T484	3.2	No	No	0	4	8
387	R:R:L495	R:R:R494	2.43	No	No	0	7	4
388	R:R:Q508	R:R:R494	7.01	No	No	0	5	4
389	R:R:F498	R:R:I505	11.3	No	No	0	8	6
390	R:R:N499	R:R:Y500	3.49	No	Yes	0	5	8
391	R:R:N499	R:R:N501	14.98	No	No	0	5	4
392	R:R:N502	R:R:T504	11.7	No	No	14	7	4
393	R:R:I505	R:R:N502	7.08	No	No	14	6	7
394	R:R:Q503	R:R:T506	2.83	Yes	No	14	3	5
395	R:R:D507	R:R:Q503	6.53	No	Yes	14	3	3
396	R:R:I505	R:R:T504	3.04	No	No	14	6	4
397	R:R:D507	R:R:T506	4.34	No	No	14	3	5
398	R:R:Q508	R:R:R511	4.67	No	No	0	5	4
399	R:R:A512	R:R:I509	1.62	No	No	0	6	6
400	R:R:M513	R:R:S516	7.67	No	No	0	6	6
401	R:R:F527	R:R:M513	4.98	No	No	24	9	6
402	R:R:S517	R:R:V526	4.85	No	No	0	4	5
403	R:R:F518	R:R:G520	3.01	No	No	17	9	9
404	R:R:F518	R:R:V525	7.87	No	No	17	9	8
405	R:R:E519	R:R:G523	1.64	No	No	0	2	9
406	R:R:E519	R:R:H524	22.16	No	No	0	2	4
407	R:R:G520	R:R:V525	1.84	No	No	17	9	8
408	R:R:G523	R:R:S522	3.71	No	Yes	0	9	9
409	R:R:R533	R:R:S522	6.59	Yes	Yes	17	9	9
410	R:R:M534	R:R:S522	3.07	No	Yes	17	5	9
411	R:R:H524	R:R:V526	6.92	No	No	0	4	5
412	R:R:R533	R:R:V525	2.62	Yes	No	17	9	8
413	R:R:D528	R:R:S530	7.36	No	No	0	6	5
414	R:R:D528	R:R:G531	1.68	No	No	0	6	8
415	R:R:S530	R:R:S532	4.89	No	No	0	5	7
416	R:R:M534	R:R:R533	12.41	No	Yes	17	5	9
417	R:R:A535	R:R:D554	4.63	No	Yes	40	6	5
418	R:R:A535	R:R:T556	1.68	No	No	40	6	1
419	R:R:W536	R:R:Y552	4.82	No	No	0	3	4
420	R:R:D554	R:R:W536	10.05	Yes	No	0	5	3
421	R:R:T537	R:R:Y553	4.99	No	Yes	25	6	6
422	R:R:E540	R:R:L538	2.65	No	No	0	6	4
423	R:R:K549	R:R:L538	2.82	No	No	0	3	4
424	R:R:I539	R:R:I550	2.94	No	Yes	41	7	7
425	R:R:G551	R:R:I539	1.76	No	No	41	7	7
426	R:R:E540	R:R:Y547	17.96	No	Yes	26	6	5
427	R:R:Q541	R:R:Q543	11.52	No	No	0	9	8
428	R:R:L542	R:R:Y547	7.03	No	Yes	26	4	5
429	R:R:K548	R:R:Q543	12.2	No	No	0	4	8
430	R:R:K567	R:R:Q543	16.27	No	No	0	1	8
431	R:R:G544	R:R:G545	2.11	No	No	0	4	4
432	R:R:G545	R:R:S546	1.86	No	No	0	4	1
433	R:R:K549	R:R:Y552	4.78	No	No	0	3	4
434	R:R:G551	R:R:I550	3.53	No	Yes	41	7	7
435	R:R:I550	R:R:W562	10.57	Yes	Yes	0	7	5
436	R:R:S555	R:R:Y553	5.09	No	Yes	0	4	6
437	R:R:D558	R:R:Y553	4.6	No	Yes	25	4	6
438	R:R:L560	R:R:Y553	5.86	No	Yes	0	7	6
439	R:R:D554	R:R:T556	11.56	Yes	No	40	5	1
440	R:R:D554	R:R:D559	7.98	Yes	No	0	5	4
441	R:R:K557	R:R:T556	12.01	No	No	0	3	1
442	R:R:D559	R:R:K557	8.3	No	No	0	4	3
443	R:R:L560	R:R:W562	6.83	No	Yes	0	7	5
444	R:R:K564	R:R:W562	18.57	No	Yes	0	4	5
445	R:R:S563	R:R:T565	6.4	No	No	0	1	3
446	R:R:D566	R:R:W568	2.23	No	Yes	0	5	9
447	R:R:G571	R:R:W568	2.81	No	Yes	0	4	9
448	R:R:P573	R:R:W568	13.51	Yes	Yes	12	5	9
449	R:R:G570	R:R:G571	2.11	No	No	0	6	4
450	R:R:G571	R:R:S572	3.71	No	No	0	4	3
451	R:R:P573	R:R:S572	3.56	Yes	No	0	5	3
452	R:R:P573	R:R:P574	1.95	Yes	No	0	5	9
453	R:R:D576	R:R:Q577	3.92	No	No	0	9	5
454	R:R:D751	R:R:T578	10.12	No	Yes	7	8	6
455	R:R:T578	R:R:V752	1.59	Yes	No	0	6	5
456	R:R:S753	R:R:T578	1.6	Yes	Yes	0	2	6
457	R:R:S753	R:R:V580	1.62	Yes	No	0	2	4
458	R:R:L755	R:R:V580	10.43	Yes	No	0	4	4
459	R:R:I581	R:R:V752	6.14	No	No	0	2	5
460	R:R:I581	R:R:I754	2.94	No	No	0	2	5
461	R:R:K582	R:R:L755	5.64	No	Yes	0	1	4
462	R:R:K582	R:R:Q757	17.63	No	No	0	1	5
463	R:R:L758	R:R:R585	4.86	Yes	No	0	5	5
464	R:R:D831	R:R:R585	16.68	No	No	0	7	5
465	R:R:F586	R:R:S588	2.64	No	No	0	4	7
466	R:R:D650	R:R:L587	6.79	Yes	No	30	9	7
467	R:R:G651	R:R:L587	1.71	No	No	30	5	7
468	R:R:L587	R:R:Q830	10.65	No	No	0	7	5
469	R:R:Q589	R:R:Y652	9.02	No	No	0	2	4
470	R:R:I593	R:R:K590	5.82	No	No	0	3	3
471	R:R:F592	R:R:S596	7.93	Yes	No	20	5	3
472	R:R:F592	R:R:V644	2.62	Yes	Yes	20	5	8
473	R:R:F592	R:R:G648	4.52	Yes	No	20	5	8
474	R:R:F592	R:R:L649	7.31	Yes	No	20	5	5
475	R:R:S596	R:R:V595	1.62	No	Yes	20	3	6
476	R:R:V595	R:R:V644	1.6	Yes	Yes	20	6	8
477	R:R:F834	R:R:V595	2.62	No	Yes	0	7	6
478	R:R:S596	R:R:V644	1.62	No	Yes	20	3	8
479	R:R:S600	R:R:V597	1.62	No	No	0	3	3
480	R:R:L598	R:R:V842	4.47	No	No	0	4	5
481	R:R:S599	R:R:S600	1.63	No	No	0	7	3
482	R:R:L641	R:R:S599	3	No	No	0	8	7
483	R:R:L601	R:R:S600	3	No	No	0	3	3
484	R:R:G602	R:R:L601	1.71	No	No	0	9	3
485	R:R:G602	R:R:L641	1.71	No	No	0	9	8
486	R:R:G602	R:R:S845	1.86	No	No	0	9	8
487	R:R:I603	R:R:S638	4.64	No	No	0	8	6
488	R:R:I603	R:R:L641	2.85	No	No	0	8	8
489	R:R:V604	R:R:V608	1.6	No	No	0	3	1
490	R:R:A606	R:R:S638	1.71	No	No	0	7	6
491	R:R:C609	R:R:F853	9.78	No	Yes	0	8	9
492	R:R:L610	R:R:N631	6.87	No	No	0	8	8
493	R:R:F612	R:R:N613	8.46	No	Yes	0	8	9
494	R:R:N613	R:R:P627	1.63	Yes	No	21	9	9
495	R:R:N613	R:R:N631	2.72	Yes	No	21	9	8
496	R:R:F853	R:R:N613	15.71	Yes	Yes	21	9	9
497	R:R:N616	R:R:Y615	12.79	No	No	0	5	2
498	R:R:H618	R:R:Q623	8.65	No	No	0	6	8
499	R:R:I622	R:R:V619	13.83	No	No	0	9	5
500	R:R:Q623	R:R:R620	4.67	No	No	0	8	8
501	R:R:N624	R:R:R620	2.41	No	No	0	8	8
502	R:R:R859	R:R:Y621	7.2	No	No	0	5	4
503	R:R:N624	R:R:N800	4.09	No	No	0	8	9
504	R:R:P627	R:R:S625	5.34	No	No	0	9	9
505	R:R:D801	R:R:S625	4.42	No	No	0	9	9
506	R:R:K856	R:R:S625	4.59	No	No	0	9	9
507	R:R:L629	R:R:Q626	6.65	No	No	0	6	9
508	R:R:N631	R:R:P627	1.63	No	No	21	8	9
509	R:R:N628	R:R:Y711	3.49	No	No	0	5	5
510	R:R:K684	R:R:L629	4.23	No	No	0	9	6
511	R:R:L629	R:R:Y711	3.52	No	No	0	6	5
512	R:R:K684	R:R:N630	8.39	No	No	0	9	9
513	R:R:L852	R:R:N630	5.49	No	No	21	7	9
514	R:R:F853	R:R:N630	4.83	Yes	No	21	9	9
515	R:R:G677	R:R:T633	5.46	No	No	43	7	7
516	R:R:S680	R:R:T633	7.99	No	No	43	7	7
517	R:R:A634	R:R:L849	4.73	No	Yes	0	7	8
518	R:R:G636	R:R:V635	3.68	No	No	0	9	4
519	R:R:G636	R:R:L639	3.42	No	Yes	44	9	6
520	R:R:G636	R:R:G673	2.11	No	No	44	9	9
521	R:R:C637	R:R:S844	1.72	No	Yes	42	5	7
522	R:R:C637	R:R:S845	1.72	No	No	42	5	8
523	R:R:C637	R:R:L849	1.59	No	Yes	0	5	8
524	R:R:G673	R:R:L639	5.13	No	Yes	44	9	6
525	R:R:A640	R:R:G673	1.95	No	No	0	7	9
526	R:R:A640	R:R:I841	1.62	No	Yes	0	7	7
527	R:R:S838	R:R:V644	4.85	No	Yes	0	7	8
528	R:R:F645	R:R:P646	2.89	No	No	0	5	6
529	R:R:A665	R:R:P646	1.87	No	No	0	5	6
530	R:R:L669	R:R:P646	1.64	Yes	No	0	5	6
531	R:R:L647	R:R:R666	14.58	No	No	0	5	8
532	R:R:G648	R:R:L649	1.71	No	No	20	8	5
533	R:R:F834	R:R:G648	4.52	No	No	0	7	8
534	R:R:I654	R:R:L649	7.14	No	No	0	5	5
535	R:R:D650	R:R:G651	5.03	Yes	No	30	9	5
536	R:R:D650	R:R:F659	4.78	Yes	Yes	0	9	4
537	R:R:D650	R:R:E759	14.29	Yes	No	30	9	7
538	R:R:E759	R:R:G651	1.64	No	No	30	7	5
539	R:R:H653	R:R:Y652	7.62	No	No	0	4	4
540	R:R:I654	R:R:Y652	3.63	No	No	0	5	4
541	R:R:G655	R:R:I654	1.76	No	No	0	5	5
542	R:R:F659	R:R:R736	16.03	Yes	No	0	4	5
543	R:R:C663	R:R:C761	5.46	No	No	0	9	9
544	R:R:L667	R:R:Q664	3.99	Yes	Yes	27	5	6
545	R:R:Q664	R:R:Q729	11.52	Yes	Yes	27	6	6
546	R:R:P733	R:R:Q664	3.16	No	Yes	0	9	6
547	R:R:L734	R:R:Q664	2.66	No	Yes	0	6	6
548	R:R:L667	R:R:L725	2.77	Yes	No	27	5	8
549	R:R:L667	R:R:Q729	13.31	Yes	Yes	27	5	6
550	R:R:L725	R:R:W668	5.69	No	No	27	8	6
551	R:R:Q729	R:R:W668	21.9	Yes	No	27	6	6
552	R:R:I730	R:R:W668	2.35	No	No	0	4	6
553	R:R:G671	R:R:L670	1.71	No	No	0	6	8
554	R:R:G671	R:R:S675	3.71	No	No	0	6	9
555	R:R:F674	R:R:K777	6.2	No	No	0	9	9
556	R:R:D721	R:R:S675	2.94	Yes	No	0	9	9
557	R:R:G677	R:R:L676	1.71	No	No	0	7	7
558	R:R:L676	R:R:V718	8.94	No	Yes	0	7	7
559	R:R:G677	R:R:S680	3.71	No	No	43	7	7
560	R:R:G679	R:R:Y678	4.35	No	Yes	0	9	8
561	R:R:M681	R:R:Y678	3.59	No	Yes	0	9	8
562	R:R:F682	R:R:Y678	2.06	No	Yes	0	9	8
563	R:R:L780	R:R:Y678	10.55	No	Yes	0	8	8
564	R:R:L781	R:R:Y678	11.72	No	Yes	0	8	8
565	R:R:I809	R:R:M681	11.66	Yes	No	0	8	9
566	R:R:F682	R:R:W686	2	No	No	0	9	8
567	R:R:F682	R:R:G784	3.01	No	No	0	9	9
568	R:R:L710	R:R:T683	2.95	No	No	0	8	7
569	R:R:T683	R:R:V714	1.59	No	No	0	7	7
570	R:R:I685	R:R:L787	4.28	No	Yes	0	9	9
571	R:R:I685	R:R:I809	2.94	No	Yes	0	9	8
572	R:R:W686	R:R:W687	5.62	No	Yes	0	8	9
573	R:R:T690	R:R:W686	20.62	No	No	0	6	8
574	R:R:V691	R:R:W687	7.36	No	Yes	28	8	9
575	R:R:F692	R:R:W687	2	Yes	Yes	28	8	9
576	R:R:L710	R:R:W687	7.97	No	Yes	0	8	9
577	R:R:T791	R:R:V688	9.52	No	No	0	9	9
578	R:R:H689	R:R:L787	2.57	No	Yes	48	8	9
579	R:R:E790	R:R:H689	17.23	No	No	48	8	8
580	R:R:T690	R:R:V691	1.59	No	No	0	6	8
581	R:R:F692	R:R:V691	7.87	Yes	No	28	8	8
582	R:R:F692	R:R:T796	14.27	Yes	No	28	8	7
583	R:R:F692	R:R:K798	4.96	Yes	No	28	8	7
584	R:R:E706	R:R:P707	3.14	No	No	0	6	8
585	R:R:P707	R:R:Y711	2.78	No	No	0	8	5
586	R:R:G715	R:R:V714	1.84	No	No	0	1	7
587	R:R:V714	R:R:V718	1.6	No	Yes	0	7	7
588	R:R:G719	R:R:V718	1.84	No	Yes	46	3	7
589	R:R:V718	R:R:V722	1.6	Yes	No	46	7	4
590	R:R:G719	R:R:V722	3.68	No	No	46	3	4
591	R:R:D721	R:R:M720	6.93	Yes	No	45	9	6
592	R:R:M720	R:R:Y776	7.18	No	No	45	6	7
593	R:R:D721	R:R:Y776	2.3	Yes	No	45	9	7
594	R:R:L725	R:R:Q729	11.98	No	Yes	27	8	6
595	R:R:A726	R:R:I730	3.25	No	No	0	4	4
596	R:R:D732	R:R:W728	3.35	Yes	No	49	8	9
597	R:R:W728	R:R:W769	25.3	No	No	49	9	8
598	R:R:D732	R:R:P733	3.22	Yes	No	0	8	9
599	R:R:D732	R:R:S763	2.94	Yes	No	0	8	8
600	R:R:D732	R:R:W769	13.4	Yes	No	49	8	8
601	R:R:C761	R:R:L734	3.17	No	No	0	9	6
602	R:R:L734	R:R:S763	4.5	No	No	0	6	8
603	R:R:H735	R:R:T737	9.58	No	No	0	4	3
604	R:R:I738	R:R:Q757	6.86	No	No	0	4	5
605	R:R:E739	R:R:H760	9.85	No	No	0	4	4
606	R:R:Q757	R:R:T740	11.34	No	No	0	5	3
607	R:R:F741	R:R:L758	4.87	No	Yes	0	5	5
608	R:R:F741	R:R:S828	2.64	No	No	0	5	6
609	R:R:E744	R:R:I754	9.56	No	No	0	5	5
610	R:R:E744	R:R:P756	14.15	No	No	0	5	5
611	R:R:E745	R:R:K747	4.05	No	No	0	2	3
612	R:R:E745	R:R:S753	2.87	No	Yes	0	2	2
613	R:R:P746	R:R:S753	3.56	No	Yes	0	5	2
614	R:R:I754	R:R:P746	20.32	No	No	0	5	5
615	R:R:D749	R:R:V752	10.22	No	No	0	4	5
616	R:R:L755	R:R:P756	1.64	Yes	No	0	4	5
617	R:R:E759	R:R:L758	6.63	No	Yes	0	7	5
618	R:R:L758	R:R:Q830	2.66	Yes	No	0	5	5
619	R:R:M766	R:R:S762	6.13	No	No	0	5	5
620	R:R:L770	R:R:M766	5.65	No	No	0	5	5
621	R:R:L770	R:R:W769	9.11	No	No	0	5	8
622	R:R:G771	R:R:Y774	2.9	No	No	0	4	6
623	R:R:F773	R:R:K777	7.44	No	No	0	6	9
624	R:R:A820	R:R:Y774	5.34	No	No	0	7	6
625	R:R:G778	R:R:L781	3.42	No	No	0	7	8
626	R:R:G778	R:R:L782	1.71	No	No	0	7	4
627	R:R:L779	R:R:L782	2.77	No	No	0	6	4
628	R:R:A813	R:R:L781	6.3	No	No	0	7	8
629	R:R:G784	R:R:L787	1.71	No	Yes	0	9	9
630	R:R:I785	W:W:?902	2.79	No	Yes	0	6	0
631	R:R:E790	R:R:L787	2.65	No	Yes	48	8	9
632	R:R:A788	W:W:?902	4.62	No	Yes	0	9	0
633	R:R:T791	R:R:V794	1.59	No	No	0	9	8
634	R:R:K792	R:R:S793	3.06	No	No	0	9	7
635	R:R:K792	S:S:Y691	3.58	No	Yes	10	9	6
636	R:R:K792	W:W:?902	9.65	No	Yes	10	9	0
637	R:R:S793	R:R:V794	1.62	No	No	0	7	8
638	R:R:T796	R:R:V794	1.59	No	No	0	7	8
639	R:R:H802	R:R:S795	5.58	No	No	0	9	7
640	R:R:K798	R:R:T796	3	No	No	28	7	7
641	R:R:D801	R:R:I799	2.8	No	No	0	9	8
642	R:R:D801	R:R:V805	2.92	No	No	0	9	9
643	R:R:H802	R:R:R803	4.51	No	No	0	9	8
644	R:R:R803	S:S:R679	4.26	No	No	0	8	9
645	R:R:A804	R:R:M807	3.22	No	No	0	6	7
646	R:R:A804	R:R:V851	1.7	No	No	0	6	7
647	R:R:G806	R:R:V805	1.84	No	No	47	7	9
648	R:R:I809	R:R:V805	3.07	Yes	No	47	8	9
649	R:R:G806	R:R:I809	3.53	No	Yes	47	7	8
650	R:R:Y810	S:S:M694	3.59	No	No	10	9	6
651	R:R:Y810	S:S:N698	5.81	No	No	0	9	9
652	R:R:Y810	W:W:?902	8.02	No	Yes	10	9	0
653	R:R:N811	S:S:Y697	4.65	No	No	0	8	9
654	R:R:T848	R:R:V812	1.59	No	No	0	8	8
655	R:R:A840	R:R:L815	3.15	No	No	0	6	7
656	R:R:A820	R:R:P821	1.87	No	No	0	7	6
657	R:R:P821	R:R:V822	1.77	No	No	0	6	6
658	R:R:F836	R:R:V822	2.62	No	No	0	6	6
659	R:R:A833	R:R:T823	1.68	No	No	0	5	7
660	R:R:I825	S:S:V719	4.61	No	No	0	6	6
661	R:R:D831	R:R:Q829	6.53	No	No	0	7	5
662	R:R:A832	R:R:A835	1.79	No	No	0	6	5
663	R:R:F836	S:S:V709	2.62	No	No	0	6	6
664	R:R:S838	R:R:V842	1.62	No	No	0	7	5
665	R:R:A840	R:R:I841	3.25	No	Yes	0	6	7
666	R:R:I841	R:R:S844	3.1	Yes	Yes	0	7	7
667	R:R:F843	R:R:I847	8.79	No	No	0	5	4
668	R:R:F843	S:S:Y697	2.06	No	No	0	5	9
669	R:R:S844	R:R:S845	1.63	Yes	No	42	7	8
670	R:R:S844	R:R:T848	3.2	Yes	No	0	7	8
671	R:R:I847	R:R:Y846	2.42	No	No	0	4	8
672	R:R:L849	R:R:T848	4.42	Yes	No	0	8	8
673	R:R:L849	R:R:L852	2.77	Yes	No	0	8	7
674	R:R:V850	R:R:V851	6.41	No	No	0	5	7
675	R:R:F853	R:R:L852	8.53	Yes	No	21	9	7
676	R:R:F853	R:R:K856	4.96	Yes	No	0	9	9
677	R:R:P855	R:R:V854	3.53	No	No	0	9	6
678	R:R:I861	R:R:L860	5.71	No	No	0	4	6
679	S:S:P50	S:S:P51	1.95	No	No	0	2	2
680	S:S:P50	S:S:R89	8.65	No	No	0	2	9
681	S:S:F98	S:S:P50	18.78	No	No	0	4	2
682	S:S:S52	S:S:S53	3.26	No	Yes	0	5	4
683	S:S:P54	S:S:S53	3.56	Yes	Yes	0	3	4
684	S:S:S53	S:S:Y97	7.63	Yes	Yes	0	4	8
685	S:S:F98	S:S:S53	6.61	No	Yes	0	4	4
686	S:S:P54	S:S:P55	1.95	Yes	No	0	3	2
687	S:S:L56	S:S:P54	1.64	No	Yes	0	6	3
688	S:S:P54	S:S:Q386	11.05	Yes	Yes	0	3	5
689	S:S:F98	S:S:P55	10.11	No	No	0	4	2
690	S:S:D100	S:S:P55	4.83	No	No	0	3	2
691	S:S:L56	S:S:Y97	10.55	No	Yes	0	6	8
692	S:S:H127	S:S:S57	9.76	Yes	No	0	8	4
693	S:S:L128	S:S:S57	6.01	No	No	0	5	4
694	S:S:I58	S:S:L99	2.85	No	No	0	8	8
695	S:S:I58	S:S:L101	11.42	No	No	0	8	5
696	S:S:M59	S:S:Y104	5.99	Yes	No	51	7	6
697	S:S:A120	S:S:M59	3.22	No	Yes	51	6	7
698	S:S:H127	S:S:M59	19.7	Yes	Yes	0	8	7
699	S:S:M59	S:S:V130	6.09	Yes	No	0	7	6
700	S:S:G60	S:S:L61	1.71	No	No	0	7	6
701	S:S:G60	S:S:M62	1.75	No	No	0	7	8
702	S:S:G60	S:S:L101	1.71	No	No	0	7	5
703	S:S:L61	S:S:V130	2.98	No	No	0	6	6
704	S:S:M62	S:S:P63	3.35	No	Yes	0	8	8
705	S:S:G71	S:S:P63	4.06	No	Yes	0	5	8
706	S:S:G74	S:S:P63	4.06	No	Yes	0	8	8
707	S:S:P63	S:S:T106	3.5	Yes	No	0	8	8
708	S:S:P63	S:S:V134	3.53	Yes	No	0	8	6
709	S:S:E67	S:S:T65	5.64	No	No	0	1	5
710	S:S:G71	S:S:K66	1.74	No	No	0	5	3
711	S:S:G74	S:S:K66	1.74	No	No	0	8	3
712	S:S:K66	S:S:R75	7.43	No	No	0	3	4
713	S:S:I73	S:S:S72	4.64	No	No	0	4	3
714	S:S:G74	S:S:I73	3.53	No	No	0	8	4
715	S:S:L78	S:S:R75	2.43	Yes	No	0	4	4
716	S:S:L78	S:S:V77	2.98	Yes	Yes	0	4	5
717	S:S:V77	S:S:V81	1.6	Yes	No	0	5	7
718	S:S:S352	S:S:V77	1.62	No	Yes	1	6	5
719	S:S:H355	S:S:V77	2.77	Yes	Yes	1	7	5
720	S:S:A358	S:S:V77	1.7	No	Yes	0	7	5
721	S:S:L78	S:S:P79	3.28	Yes	No	0	4	5
722	S:S:E82	S:S:L78	3.98	No	Yes	0	4	4
723	S:S:K345	S:S:P79	5.02	No	No	0	3	5
724	S:S:A80	S:S:Y338	2.67	No	Yes	0	8	7
725	S:S:E82	S:S:I85	2.73	No	No	0	4	6
726	S:S:E341	S:S:L83	2.65	No	No	0	5	7
727	S:S:K345	S:S:L83	2.82	No	No	0	3	7
728	S:S:A84	S:S:Y359	2.67	No	Yes	0	9	9
729	S:S:Q87	S:S:S331	4.33	No	Yes	1	7	8
730	S:S:K333	S:S:Q87	8.14	Yes	No	1	5	7
731	S:S:Q87	S:S:W363	4.38	No	Yes	1	7	8
732	S:S:E91	S:S:L93	10.6	No	No	0	5	6
733	S:S:E91	S:S:R95	4.65	No	No	0	5	4
734	S:S:R95	S:S:S92	2.64	No	No	0	4	5
735	S:S:L93	S:S:L94	5.54	No	No	0	6	9
736	S:S:L93	S:S:Q370	14.64	No	No	0	6	7
737	S:S:L94	S:S:M373	2.83	No	No	0	9	4
738	S:S:P96	S:S:Y97	5.56	No	Yes	0	5	8
739	S:S:I385	S:S:Y97	8.46	No	Yes	50	6	8
740	S:S:Q386	S:S:Y97	5.64	Yes	Yes	50	5	8
741	S:S:L101	S:S:L103	8.3	No	No	0	5	1
742	S:S:R102	S:S:Y104	5.14	No	No	0	2	6
743	S:S:H127	S:S:R102	3.39	Yes	No	0	8	2
744	S:S:A120	S:S:Y104	9.34	No	No	51	6	6
745	S:S:D105	S:S:T106	2.89	No	No	0	8	8
746	S:S:D105	S:S:E107	15.59	No	No	0	8	5
747	S:S:G113	S:S:T106	1.82	No	No	0	6	8
748	S:S:E107	S:S:K112	12.15	No	No	0	5	4
749	S:S:C108	S:S:C135	7.28	No	No	52	7	6
750	S:S:C108	S:S:P136	1.88	No	Yes	52	7	9
751	S:S:N110	S:S:S137	5.96	Yes	No	0	5	4
752	S:S:N110	S:S:V138	2.96	Yes	No	0	5	8
753	S:S:I141	S:S:N110	5.66	No	Yes	0	5	5
754	S:S:G113	S:S:K112	1.74	No	No	0	6	4
755	S:S:A116	S:S:G113	1.95	No	No	0	4	6
756	S:S:L114	S:S:Y118	9.38	No	Yes	0	6	7
757	S:S:F117	S:S:I142	5.02	No	No	0	7	7
758	S:S:F117	S:S:W149	6.01	No	No	0	7	7
759	S:S:D119	S:S:Y123	4.6	No	No	0	5	4
760	S:S:I121	S:S:Y390	10.88	No	No	0	6	8
761	S:S:K122	S:S:Y123	5.97	Yes	No	0	4	4
762	S:S:G124	S:S:P125	4.06	No	No	0	2	7
763	S:S:N126	S:S:P125	1.63	No	No	0	4	7
764	S:S:H127	S:S:P125	6.1	Yes	No	0	8	7
765	S:S:F388	S:S:N126	3.62	Yes	No	0	7	4
766	S:S:F388	S:S:L128	8.53	Yes	No	0	7	5
767	S:S:M129	S:S:V152	3.04	No	No	0	6	5
768	S:S:I365	S:S:M129	4.37	No	No	0	5	6
769	S:S:L369	S:S:M129	2.83	No	No	0	8	6
770	S:S:Q153	S:S:V130	8.6	Yes	No	0	9	6
771	S:S:F131	S:S:L154	4.87	Yes	No	54	7	7
772	S:S:F131	S:S:F156	6.43	Yes	No	0	7	6
773	S:S:F131	S:S:I362	6.28	Yes	No	0	7	6
774	S:S:F131	S:S:I365	2.51	Yes	No	54	7	5
775	S:S:G132	S:S:G133	2.11	No	No	8	9	6
776	S:S:G132	S:S:Q153	1.64	No	Yes	8	9	9
777	S:S:G132	S:S:S155	3.71	No	Yes	8	9	8
778	S:S:G133	S:S:T139	1.82	No	No	0	6	8
779	S:S:G133	S:S:S155	3.71	No	Yes	8	6	8
780	S:S:A157	S:S:V134	3.39	No	No	0	7	6
781	S:S:C135	S:S:P136	1.88	No	Yes	52	6	9
782	S:S:C135	S:S:V138	6.83	No	No	0	6	8
783	S:S:P136	S:S:S137	3.56	Yes	No	0	9	4
784	S:S:P136	S:S:T160	1.75	Yes	Yes	0	9	8
785	S:S:T139	S:S:V138	1.59	No	No	0	8	8
786	S:S:I142	S:S:L146	2.85	No	No	0	7	7
787	S:S:A143	S:S:Y169	9.34	No	No	0	9	7
788	S:S:Q147	S:S:Y171	16.91	No	No	0	6	6
789	S:S:H393	S:S:N150	6.38	No	No	0	1	8
790	S:S:I399	S:S:V152	3.07	No	No	0	6	5
791	S:S:Q153	S:S:S155	4.33	Yes	Yes	8	9	8
792	S:S:F172	S:S:Q153	7.03	Yes	Yes	8	8	9
793	S:S:I365	S:S:L154	2.85	No	No	54	5	7
794	S:S:F156	S:S:S155	3.96	No	Yes	0	6	8
795	S:S:A358	S:S:F156	2.77	No	No	0	7	6
796	S:S:A158	S:S:T160	1.68	No	Yes	0	8	8
797	S:S:A158	S:S:F172	2.77	No	Yes	8	8	8
798	S:S:A158	S:S:R174	5.53	No	Yes	8	8	9
799	S:S:P161	S:S:T160	1.75	No	Yes	0	6	8
800	S:S:L163	S:S:T160	4.42	No	Yes	0	8	8
801	S:S:P161	S:S:S178	3.56	No	No	8	6	8
802	S:S:N180	S:S:P161	6.52	Yes	No	8	6	6
803	S:S:Q206	S:S:V162	5.73	No	No	38	6	6
804	S:S:L163	S:S:Y169	4.69	No	No	0	8	7
805	S:S:F172	S:S:L163	4.87	Yes	No	0	8	8
806	S:S:D165	S:S:K167	6.91	No	No	0	8	2
807	S:S:D165	S:S:K168	11.06	No	No	0	8	5
808	S:S:K166	S:S:P170	1.67	No	No	0	7	8
809	S:S:G420	S:S:K166	1.74	No	No	0	8	7
810	S:S:K168	S:S:Y169	9.55	No	No	0	5	7
811	S:S:P170	S:S:Y171	2.78	No	No	0	8	6
812	S:S:L400	S:S:Y171	3.52	No	No	0	3	6
813	S:S:F172	S:S:R174	2.14	Yes	Yes	8	8	9
814	S:S:F173	S:S:L400	3.65	No	No	0	7	3
815	S:S:F173	S:S:M403	11.2	No	Yes	31	7	5
816	S:S:F173	S:S:F417	7.5	No	No	31	7	9
817	S:S:R174	S:S:S178	6.59	Yes	No	8	9	8
818	S:S:E421	S:S:R174	15.12	No	Yes	0	7	9
819	S:S:T175	S:S:V176	3.17	No	No	1	7	6
820	S:S:T175	S:S:Y357	3.75	No	Yes	1	7	5
821	S:S:R422	S:S:T175	2.59	Yes	No	1	9	7
822	S:S:P177	S:S:V176	3.53	No	No	0	6	6
823	S:S:V176	S:S:Y357	2.52	No	Yes	1	6	5
824	S:S:N180	S:S:S178	5.96	Yes	No	8	6	8
825	S:S:D179	S:S:W284	7.82	No	Yes	0	7	6
826	S:S:N180	S:S:V211	2.96	Yes	No	0	6	6
827	S:S:D214	S:S:N180	4.04	No	Yes	0	5	6
828	S:S:N183	S:S:V182	2.96	No	No	0	9	5
829	S:S:I186	S:S:V182	3.07	No	No	0	7	5
830	S:S:N183	S:S:P184	1.63	No	No	0	9	4
831	S:S:L215	S:S:N183	13.73	No	No	0	8	9
832	S:S:P184	S:S:Y442	5.56	No	Yes	0	4	6
833	S:S:A185	S:S:F428	2.77	No	Yes	32	8	8
834	S:S:A185	S:S:Y442	8.01	No	Yes	32	8	6
835	S:S:K188	S:S:L187	2.82	No	No	0	5	5
836	S:S:K188	S:S:Y442	5.97	No	Yes	0	5	6
837	S:S:D447	S:S:K188	11.06	No	No	0	4	5
838	S:S:L189	S:S:L190	2.77	No	No	0	6	5
839	S:S:L190	S:S:W195	2.28	No	Yes	0	5	9
840	S:S:D223	S:S:K191	5.53	No	No	0	7	5
841	S:S:H192	S:S:Y193	6.53	No	Yes	0	4	8
842	S:S:H192	S:S:L449	3.86	No	No	0	4	7
843	S:S:W195	S:S:Y193	12.54	Yes	Yes	0	9	8
844	S:S:I456	S:S:Y193	3.63	Yes	Yes	55	4	8
845	S:S:F458	S:S:Y193	8.25	No	Yes	55	9	8
846	S:S:K196	S:S:Q194	4.07	No	No	0	5	6
847	S:S:I250	S:S:W195	5.87	No	Yes	0	9	9
848	S:S:Q278	S:S:W195	4.38	No	Yes	0	8	9
849	S:S:P464	S:S:W195	8.11	No	Yes	0	9	9
850	S:S:I224	S:S:K196	10.18	No	No	0	6	5
851	S:S:E225	S:S:R197	8.14	No	No	0	5	6
852	S:S:R197	S:S:V248	7.85	No	No	0	6	7
853	S:S:D466	S:S:R197	3.57	No	No	0	9	6
854	S:S:G199	S:S:V198	1.84	No	No	0	8	8
855	S:S:I226	S:S:V198	6.14	No	No	0	6	8
856	S:S:I250	S:S:V198	3.07	No	No	0	9	8
857	S:S:R212	S:S:T200	18.11	Yes	No	0	5	7
858	S:S:T200	S:S:T229	6.28	No	No	0	7	6
859	S:S:F232	S:S:L201	2.44	No	No	0	7	7
860	S:S:R212	S:S:T202	3.88	Yes	No	0	5	6
861	S:S:S231	S:S:T202	3.2	No	No	0	7	6
862	S:S:Q203	S:S:V205	5.73	Yes	No	0	7	4
863	S:S:F208	S:S:Q203	8.2	Yes	Yes	22	7	7
864	S:S:F232	S:S:Q203	8.2	No	Yes	0	7	7
865	S:S:F255	S:S:Q203	2.34	Yes	Yes	22	8	7
866	S:S:D256	S:S:Q203	10.44	Yes	Yes	22	7	7
867	S:S:F208	S:S:R207	18.17	Yes	No	0	7	5
868	S:S:R207	S:S:W284	6	No	Yes	0	5	6
869	S:S:F208	S:S:F255	2.14	Yes	Yes	22	7	8
870	S:S:D256	S:S:F208	5.97	Yes	Yes	22	7	7
871	S:S:Q254	S:S:V211	2.87	No	No	0	6	6
872	S:S:L215	S:S:R212	3.64	No	Yes	0	8	5
873	S:S:R212	S:S:T216	5.17	Yes	No	0	5	5
874	S:S:I226	S:S:R212	3.76	No	Yes	0	6	5
875	S:S:L215	S:S:L219	5.54	No	No	0	8	6
876	S:S:L219	S:S:V218	2.98	No	No	0	6	3
877	S:S:E222	S:S:G221	4.91	No	No	0	5	3
878	S:S:D223	S:S:I224	2.8	No	No	0	7	6
879	S:S:E225	S:S:I224	4.1	No	No	0	5	6
880	S:S:D228	S:S:S227	5.89	No	No	0	5	4
881	S:S:D228	S:S:L243	4.07	No	No	0	5	8
882	S:S:D228	S:S:N246	14.81	No	No	0	5	6
883	S:S:E230	S:S:S239	4.31	No	No	0	8	6
884	S:S:F232	S:S:P236	8.67	No	Yes	0	7	5
885	S:S:N234	S:S:S233	10.43	No	No	0	4	4
886	S:S:D235	S:S:P236	6.44	No	Yes	56	6	5
887	S:S:C237	S:S:D235	6.22	No	No	56	3	6
888	S:S:C237	S:S:P236	7.53	No	Yes	56	3	5
889	S:S:K262	S:S:P236	3.35	No	Yes	0	5	5
890	S:S:C237	S:S:C266	7.28	No	No	0	3	7
891	S:S:S239	S:S:T238	1.6	No	No	0	6	3
892	S:S:S239	S:S:V240	3.23	No	No	0	6	6
893	S:S:E270	S:S:K241	9.45	No	No	0	5	4
894	S:S:E270	S:S:K244	16.2	No	No	0	5	8
895	S:S:K244	S:S:M272	11.52	No	No	57	8	7
896	S:S:K244	S:S:Y277	2.39	No	Yes	57	8	8
897	S:S:D247	S:S:Y277	4.6	No	Yes	0	8	8
898	S:S:K276	S:S:R249	4.95	No	No	0	7	9
899	S:S:R249	S:S:T468	2.59	No	Yes	0	9	6
900	S:S:I251	S:S:W279	19.97	No	No	0	9	9
901	S:S:G253	S:S:L252	1.71	Yes	No	0	5	6
902	S:S:I280	S:S:L252	4.28	No	No	0	7	6
903	S:S:G253	S:S:Q254	4.93	Yes	No	0	5	6
904	S:S:F255	S:S:G253	3.01	Yes	Yes	0	8	5
905	S:S:G253	S:S:I281	1.76	Yes	No	0	5	6
906	S:S:P282	S:S:Q254	7.9	Yes	No	0	5	6
907	S:S:F255	S:S:V263	6.55	Yes	No	0	8	7
908	S:S:D256	S:S:N258	4.04	Yes	No	22	7	2
909	S:S:D256	S:S:M259	4.16	Yes	No	22	7	4
910	S:S:Q257	S:S:Y285	5.64	No	Yes	2	6	5
911	S:S:Q257	S:S:W289	5.48	No	Yes	2	6	9
912	S:S:M259	S:S:N258	4.21	No	No	22	4	2
913	S:S:A260	S:S:F264	2.77	No	Yes	0	8	7
914	S:S:A260	S:S:W289	2.59	No	Yes	0	8	9
915	S:S:F264	S:S:V263	10.49	Yes	No	0	7	7
916	S:S:A267	S:S:F264	2.77	No	Yes	0	8	7
917	S:S:F264	S:S:W279	12.03	Yes	No	0	7	9
918	S:S:F264	S:S:L307	3.65	Yes	No	2	7	7
919	S:S:F264	S:S:M311	3.73	Yes	Yes	2	7	5
920	S:S:C265	S:S:C302	7.28	No	No	0	9	9
921	S:S:E269	S:S:Y268	3.37	No	Yes	0	5	6
922	S:S:N271	S:S:Y268	3.49	No	Yes	58	3	6
923	S:S:Y268	S:S:Y273	4.96	Yes	No	58	6	5
924	S:S:N306	S:S:Y268	20.93	No	Yes	0	6	6
925	S:S:A310	S:S:Y268	2.67	No	Yes	0	8	6
926	S:S:N271	S:S:Y273	9.3	No	No	58	3	5
927	S:S:M272	S:S:Y277	9.58	No	Yes	57	7	8
928	S:S:G274	S:S:Q459	1.64	No	No	0	8	2
929	S:S:G460	S:S:S275	1.86	No	No	0	4	5
930	S:S:K276	S:S:Y277	20.3	No	Yes	0	7	8
931	S:S:I315	S:S:Q278	2.74	No	No	0	5	8
932	S:S:W279	S:S:Y314	2.89	No	Yes	0	9	5
933	S:S:I281	S:S:P282	6.77	No	Yes	0	6	5
934	S:S:I281	S:S:Y285	3.63	No	Yes	0	6	5
935	S:S:G283	S:S:P282	2.03	No	Yes	0	6	5
936	S:S:P282	S:S:W284	4.05	Yes	Yes	0	5	6
937	S:S:G283	S:S:G316	2.11	No	Yes	0	6	5
938	S:S:D318	S:S:G283	6.71	Yes	No	0	6	6
939	S:S:W284	S:S:Y285	6.75	Yes	Yes	0	6	5
940	S:S:D318	S:S:W284	2.23	Yes	Yes	0	6	6
941	S:S:W289	S:S:Y285	10.61	Yes	Yes	2	9	5
942	S:S:E286	S:S:P287	11	No	No	0	4	2
943	S:S:W289	S:S:W290	17.81	Yes	Yes	2	9	6
944	S:S:M311	S:S:W289	5.82	Yes	Yes	2	5	9
945	S:S:W289	S:S:Y314	2.89	Yes	Yes	2	9	5
946	S:S:E291	S:S:W290	4.36	No	Yes	2	2	6
947	S:S:R304	S:S:W290	4	No	Yes	2	1	6
948	S:S:F431	S:S:W290	7.02	Yes	Yes	2	5	6
949	S:S:E436	S:S:W290	4.36	No	Yes	2	4	6
950	S:S:E291	S:S:R304	18.61	No	No	2	2	1
951	S:S:C302	S:S:L303	1.59	No	No	0	9	6
952	S:S:L303	S:S:N306	16.48	No	No	0	6	6
953	S:S:L308	S:S:R304	4.86	No	No	0	1	1
954	S:S:L307	S:S:M311	4.24	No	Yes	2	7	5
955	S:S:M311	S:S:Y314	5.99	Yes	Yes	2	5	5
956	S:S:F431	S:S:M311	3.73	Yes	Yes	2	5	5
957	S:S:E312	S:S:F431	20.99	No	Yes	2	7	5
958	S:S:D433	S:S:E312	2.6	No	No	2	3	7
959	S:S:E312	S:S:R457	4.65	No	Yes	2	7	1
960	S:S:G313	S:S:Q430	3.29	No	Yes	0	5	9
961	S:S:G316	S:S:Y314	2.9	Yes	Yes	0	5	5
962	S:S:F431	S:S:Y314	3.09	Yes	Yes	2	5	5
963	S:S:G316	S:S:I315	3.53	Yes	No	0	5	5
964	S:S:G316	S:S:V317	1.84	Yes	No	0	5	6
965	S:S:G316	S:S:T429	1.82	Yes	No	0	5	5
966	S:S:F428	S:S:V317	3.93	Yes	No	0	8	6
967	S:S:D318	S:S:F319	4.78	Yes	Yes	0	6	4
968	S:S:D318	S:S:K427	5.53	Yes	No	0	6	5
969	S:S:F319	S:S:K353	4.96	Yes	No	1	4	4
970	S:S:F319	S:S:F354	6.43	Yes	No	1	4	5
971	S:S:F319	S:S:Y357	5.16	Yes	Yes	1	4	5
972	S:S:E320	S:S:P321	9.43	No	No	0	4	4
973	S:S:E320	S:S:T425	5.64	No	No	0	4	3
974	S:S:E320	S:S:K427	8.1	No	No	0	4	5
975	S:S:L322	S:S:P321	3.28	No	No	0	4	4
976	S:S:L322	S:S:V411	2.98	No	Yes	0	4	7
977	S:S:G413	S:S:S323	1.86	No	No	0	9	6
978	S:S:K325	S:S:S324	4.59	No	No	0	3	4
979	S:S:I327	S:S:K325	4.36	No	No	0	3	3
980	S:S:Q326	S:S:T334	2.83	No	Yes	33	4	8
981	S:S:P335	S:S:Q326	7.9	No	No	33	4	4
982	S:S:Q326	S:S:Q336	8.96	No	No	33	4	3
983	S:S:G332	S:S:K328	6.97	Yes	No	0	7	2
984	S:S:S331	S:S:T329	4.8	Yes	No	1	8	7
985	S:S:G332	S:S:T329	1.82	Yes	No	1	7	7
986	S:S:I330	S:S:W363	14.09	No	Yes	0	5	8
987	S:S:I330	S:S:K367	2.91	No	No	0	5	7
988	S:S:G332	S:S:S331	3.71	Yes	Yes	1	7	8
989	S:S:K333	S:S:S331	15.3	Yes	Yes	1	5	8
990	S:S:S331	S:S:Y359	2.54	Yes	Yes	1	8	9
991	S:S:S331	S:S:W363	2.47	Yes	Yes	1	8	8
992	S:S:G332	S:S:K333	3.49	Yes	Yes	1	7	5
993	S:S:K333	S:S:Q337	8.14	Yes	Yes	0	5	5
994	S:S:P335	S:S:T334	5.25	No	Yes	33	4	8
995	S:S:Q336	S:S:T334	8.5	No	Yes	33	3	8
996	S:S:Q337	S:S:T334	14.17	Yes	Yes	0	5	8
997	S:S:Q336	S:S:R340	8.18	No	No	0	3	2
998	S:S:Q337	S:S:R340	4.67	Yes	No	0	5	2
999	S:S:E341	S:S:Q337	3.82	No	Yes	0	5	5
1000	S:S:H355	S:S:Y338	2.18	Yes	Yes	1	7	7
1001	S:S:G356	S:S:Y338	4.35	No	Yes	1	5	7
1002	S:S:Y338	S:S:Y359	15.89	Yes	Yes	1	7	9
1003	S:S:V411	S:S:Y338	2.52	Yes	Yes	1	7	7
1004	S:S:N343	S:S:Y342	5.81	No	No	1	3	7
1005	S:S:R346	S:S:Y342	9.26	Yes	No	1	4	7
1006	S:S:H355	S:S:Y342	15.24	Yes	No	1	7	7
1007	S:S:N343	S:S:R346	6.03	No	Yes	1	3	4
1008	S:S:R346	S:S:V349	3.92	Yes	No	0	4	1
1009	S:S:P351	S:S:R346	7.21	No	Yes	0	3	4
1010	S:S:G348	S:S:S347	3.71	No	No	0	5	3
1011	S:S:G350	S:S:P351	4.06	No	No	0	3	3
1012	S:S:H355	S:S:S352	11.16	Yes	No	1	7	6
1013	S:S:F354	S:S:K353	24.82	No	No	1	5	4
1014	S:S:G356	S:S:H355	4.77	No	Yes	1	5	7
1015	S:S:D360	S:S:G356	1.68	Yes	No	1	9	5
1016	S:S:T412	S:S:Y357	6.24	Yes	Yes	1	9	5
1017	S:S:R422	S:S:Y357	7.2	Yes	Yes	1	9	5
1018	S:S:D360	S:S:Y359	3.45	Yes	Yes	1	9	9
1019	S:S:W363	S:S:Y359	16.4	Yes	Yes	1	8	9
1020	S:S:V411	S:S:Y359	2.52	Yes	Yes	1	7	9
1021	S:S:D360	S:S:G361	1.68	Yes	No	0	9	8
1022	S:S:D360	S:S:G410	3.35	Yes	No	0	9	9
1023	S:S:D360	S:S:V411	8.76	Yes	Yes	1	9	7
1024	S:S:D360	S:S:T412	7.23	Yes	Yes	1	9	9
1025	S:S:G361	S:S:V364	3.68	No	No	0	8	7
1026	S:S:F408	S:S:W363	2	No	Yes	0	9	8
1027	S:S:F408	S:S:V364	5.24	No	No	0	9	7
1028	S:S:V364	S:S:V415	1.6	No	No	0	7	8
1029	S:S:K367	S:S:Q370	4.07	No	No	0	7	7
1030	S:S:A402	S:S:T368	1.68	No	No	0	5	8
1031	S:S:M403	S:S:T368	7.53	Yes	No	0	5	8
1032	S:S:L369	S:S:M373	2.83	No	No	0	8	4
1033	S:S:E374	S:S:Q370	6.37	No	No	0	1	7
1034	S:S:E374	S:S:R371	3.49	No	No	0	1	4
1035	S:S:H382	S:S:M373	2.63	No	No	0	3	4
1036	S:S:A378	S:S:T375	1.68	No	No	0	2	1
1037	S:S:H377	S:S:L376	2.57	Yes	No	0	1	7
1038	S:S:H377	S:S:S379	6.97	Yes	No	0	1	1
1039	S:S:H377	S:S:S380	4.18	Yes	No	0	1	2
1040	S:S:H377	S:S:R381	3.39	Yes	No	0	1	4
1041	S:S:A378	S:S:H382	2.93	No	No	0	2	3
1042	S:S:R384	S:S:S380	5.27	No	No	0	3	2
1043	S:S:R381	S:S:R384	12.79	No	No	0	4	3
1044	S:S:Q383	S:S:Q386	15.36	No	Yes	0	2	5
1045	S:S:D387	S:S:Q383	2.61	No	No	0	4	2
1046	S:S:D387	S:S:R384	4.76	No	No	0	4	3
1047	S:S:I385	S:S:Q386	2.74	No	Yes	50	6	5
1048	S:S:D392	S:S:F388	2.39	No	Yes	53	6	7
1049	S:S:F388	S:S:L395	3.65	Yes	Yes	53	7	6
1050	S:S:D392	S:S:T394	10.12	No	No	0	6	3
1051	S:S:D392	S:S:L395	17.64	No	Yes	53	6	6
1052	S:S:H393	S:S:R397	7.9	No	No	0	1	3
1053	S:S:I398	S:S:T394	3.04	No	No	0	4	3
1054	S:S:G396	S:S:L395	1.71	No	Yes	0	4	6
1055	S:S:I398	S:S:L395	2.85	No	Yes	0	4	6
1056	S:S:G396	S:S:I399	3.53	No	No	0	4	6
1057	S:S:N401	S:S:R397	2.41	No	No	0	4	3
1058	S:S:M403	S:S:T406	4.52	Yes	No	31	5	7
1059	S:S:F417	S:S:M403	2.49	No	Yes	31	9	5
1060	S:S:F408	S:S:T406	2.59	No	No	0	9	7
1061	S:S:F417	S:S:T406	2.59	No	No	31	9	7
1062	S:S:N407	S:S:Q414	11.88	No	No	59	4	3
1063	S:S:N407	S:S:V416	5.91	No	No	59	4	5
1064	S:S:F409	S:S:G410	3.01	No	No	0	2	9
1065	S:S:F409	S:S:G413	6.02	No	No	0	2	9
1066	S:S:T412	S:S:V411	4.76	Yes	Yes	1	9	7
1067	S:S:T412	S:S:V415	3.17	Yes	No	1	9	8
1068	S:S:R422	S:S:T412	7.76	Yes	Yes	1	9	9
1069	S:S:Q414	S:S:V416	2.87	No	No	59	3	5
1070	S:S:R422	S:S:V415	13.08	Yes	No	1	9	8
1071	S:S:M423	S:S:V416	3.04	No	No	0	5	5
1072	S:S:M423	S:S:R418	19.85	No	No	0	5	4
1073	S:S:E421	S:S:G420	1.64	No	No	0	7	8
1074	S:S:G424	S:S:R422	4.5	No	Yes	0	6	9
1075	S:S:G424	S:S:T425	3.64	No	No	0	6	3
1076	S:S:F428	S:S:I426	5.02	Yes	No	32	8	5
1077	S:S:I426	S:S:Y442	3.63	No	Yes	32	5	6
1078	S:S:F428	S:S:Y442	3.09	Yes	Yes	32	8	6
1079	S:S:Q430	S:S:V439	2.87	Yes	No	0	9	6
1080	S:S:I456	S:S:Q430	5.49	Yes	Yes	0	4	9
1081	S:S:Q430	S:S:R457	5.84	Yes	Yes	0	9	1
1082	S:S:E436	S:S:F431	10.49	No	Yes	2	4	5
1083	S:S:Q432	S:S:V437	10.03	No	No	0	7	4
1084	S:S:Q432	S:S:R457	17.52	No	Yes	0	7	1
1085	S:S:D433	S:S:R457	14.29	No	Yes	2	3	1
1086	S:S:V437	S:S:V439	1.6	No	No	0	4	6
1087	S:S:G440	S:S:K438	1.74	Yes	No	0	7	3
1088	S:S:G440	S:S:V439	1.84	Yes	No	0	7	6
1089	S:S:E441	S:S:G440	1.64	No	Yes	0	4	7
1090	S:S:G440	S:S:I451	1.76	Yes	No	0	7	4
1091	S:S:E441	S:S:E450	2.54	No	No	0	4	3
1092	S:S:A444	S:S:Y442	6.67	No	Yes	0	4	6
1093	S:S:N443	S:S:V445	5.91	No	No	0	4	1
1094	S:S:N443	S:S:T448	5.85	No	No	0	4	3
1095	S:S:A446	S:S:T448	1.68	No	No	0	2	3
1096	S:S:I451	S:S:L449	5.71	No	No	0	4	7
1097	S:S:I452	S:S:T455	12.16	No	No	0	1	1
1098	S:S:D454	S:S:T455	4.34	No	No	0	2	1
1099	S:S:F458	S:S:I456	2.51	No	Yes	55	9	4
1100	S:S:F458	S:S:P464	2.89	No	No	0	9	9
1101	S:S:E462	S:S:S461	5.75	No	No	0	3	4
1102	S:S:P463	S:S:P464	1.95	No	No	0	5	9
1103	S:S:D466	S:S:K465	2.77	No	No	0	9	4
1104	S:S:D466	S:S:K467	11.06	No	No	0	9	5
1105	S:S:K467	S:S:T468	3	No	Yes	0	5	6
1106	S:S:I470	S:S:T468	3.04	No	Yes	0	3	6
1107	S:S:S640	S:S:T468	6.4	No	Yes	0	3	6
1108	S:S:D638	S:S:I469	4.2	No	No	0	8	2
1109	S:S:I469	S:S:I639	13.25	No	Yes	0	2	4
1110	S:S:E472	S:S:I470	2.73	No	No	60	1	3
1111	S:S:I470	S:S:R642	6.26	No	Yes	60	3	4
1112	S:S:I641	S:S:L471	5.71	Yes	No	0	5	3
1113	S:S:E472	S:S:R642	6.98	No	Yes	60	1	4
1114	S:S:I641	S:S:Q473	12.35	Yes	No	0	5	4
1115	S:S:G541	S:S:L474	1.71	Yes	No	0	5	3
1116	S:S:R475	S:S:Y628	5.14	No	Yes	23	4	4
1117	S:S:L645	S:S:R475	9.72	No	No	23	5	4
1118	S:S:G541	S:S:K476	1.74	Yes	No	0	5	4
1119	S:S:I477	S:S:S478	9.29	No	No	0	7	6
1120	S:S:I477	S:S:P717	8.47	No	No	0	7	5
1121	S:S:F721	S:S:I477	5.02	Yes	No	0	7	7
1122	S:S:L481	S:S:S478	12.01	Yes	No	0	5	6
1123	S:S:L479	S:S:P480	4.93	No	Yes	0	1	3
1124	S:S:L481	S:S:P480	3.28	Yes	Yes	0	5	3
1125	S:S:P480	S:S:S483	1.78	Yes	No	0	3	4
1126	S:S:I484	S:S:P480	6.77	No	Yes	0	3	3
1127	S:S:L481	S:S:L485	4.15	Yes	No	9	5	5
1128	S:S:F721	S:S:L481	2.44	Yes	Yes	9	7	5
1129	S:S:S483	S:S:S486	1.63	No	No	0	4	3
1130	S:S:I534	S:S:L485	2.85	Yes	No	9	8	5
1131	S:S:F721	S:S:L485	6.09	Yes	No	9	7	5
1132	S:S:S486	S:S:T489	1.6	No	Yes	9	3	7
1133	S:S:F535	S:S:S486	2.64	Yes	No	9	6	3
1134	S:S:I490	S:S:T489	3.04	No	Yes	0	1	7
1135	S:S:T489	S:S:Y531	7.49	Yes	Yes	9	7	8
1136	S:S:I534	S:S:T489	3.04	Yes	Yes	9	8	7
1137	S:S:F535	S:S:T489	7.78	Yes	Yes	9	6	7
1138	S:S:G492	S:S:L491	1.71	No	No	0	8	2
1139	S:S:G492	S:S:M495	3.49	No	No	0	8	4
1140	S:S:G492	S:S:Y531	4.35	No	Yes	0	8	8
1141	S:S:M493	S:S:M528	7.22	No	No	0	8	5
1142	S:S:M493	S:S:Y531	3.59	No	Yes	0	8	8
1143	S:S:A532	S:S:M493	1.61	No	No	0	2	8
1144	S:S:I494	S:S:S497	3.1	No	No	0	2	3
1145	S:S:C737	S:S:M495	1.62	No	No	0	4	4
1146	S:S:A496	S:S:M528	1.61	No	No	0	7	5
1147	S:S:C737	S:S:F499	2.79	No	No	10	4	7
1148	S:S:F499	S:S:F740	6.43	No	Yes	0	7	9
1149	S:S:F499	S:S:V741	2.62	No	Yes	10	7	6
1150	S:S:I504	S:S:L500	2.85	No	No	0	6	8
1151	S:S:L500	S:S:N521	4.12	No	No	0	8	8
1152	S:S:F502	S:S:L744	2.44	No	No	0	6	5
1153	S:S:F502	S:S:R748	5.34	No	No	0	6	3
1154	S:S:N503	S:S:P517	4.89	No	No	0	9	9
1155	S:S:K505	S:S:N506	4.2	No	No	0	2	4
1156	S:S:L747	S:S:N506	12.36	No	No	0	6	4
1157	S:S:N508	S:S:R507	3.62	No	No	0	6	7
1158	S:S:R507	S:S:Y518	7.2	No	No	0	7	5
1159	S:S:I512	S:S:N508	2.83	No	No	0	8	6
1160	S:S:K510	S:S:Q509	10.85	No	No	0	8	5
1161	S:S:L511	S:S:Q509	7.99	Yes	No	0	4	5
1162	S:S:I512	S:S:L511	4.28	No	Yes	0	8	4
1163	S:S:L511	S:S:L747	2.77	Yes	No	61	4	6
1164	S:S:I512	S:S:K513	2.91	No	No	0	8	8
1165	S:S:N520	S:S:S515	2.98	No	No	0	9	9
1166	S:S:K574	S:S:S515	4.59	No	No	0	9	9
1167	S:S:K743	S:S:S515	4.59	No	No	0	9	9
1168	S:S:P517	S:S:S516	3.56	No	Yes	0	9	9
1169	S:S:S516	S:S:Y518	2.54	Yes	No	0	9	5
1170	S:S:M519	S:S:S516	7.67	No	Yes	62	6	9
1171	S:S:K574	S:S:S516	3.06	No	Yes	62	9	9
1172	S:S:N520	S:S:P517	1.63	No	No	0	9	9
1173	S:S:K574	S:S:M519	5.76	No	No	62	9	6
1174	S:S:F740	S:S:N520	7.25	Yes	No	0	9	9
1175	S:S:I524	S:S:N521	4.25	No	No	0	7	8
1176	S:S:A567	S:S:I523	4.87	No	No	0	7	8
1177	S:S:A570	S:S:I523	3.25	No	No	0	7	8
1178	S:S:I523	S:S:M571	4.37	No	No	0	8	8
1179	S:S:I524	S:S:L736	5.71	No	No	0	7	7
1180	S:S:G526	S:S:L525	1.71	Yes	No	13	9	3
1181	S:S:L525	S:S:L529	2.77	No	No	13	3	5
1182	S:S:G526	S:S:G527	2.11	Yes	No	0	9	5
1183	S:S:G526	S:S:L529	1.71	Yes	No	13	9	5
1184	S:S:G526	S:S:G563	2.11	Yes	No	13	9	9
1185	S:S:G526	S:S:T566	1.82	Yes	Yes	13	9	7
1186	S:S:A567	S:S:G526	1.95	No	Yes	13	7	9
1187	S:S:G527	S:S:S530	1.86	No	No	0	5	6
1188	S:S:I559	S:S:L529	4.28	No	No	0	4	5
1189	S:S:S732	S:S:Y531	2.54	No	Yes	9	8	8
1190	S:S:T733	S:S:Y531	2.5	Yes	Yes	9	8	8
1191	S:S:A532	S:S:F535	2.77	No	Yes	0	2	6
1192	S:S:I559	S:S:S533	10.84	No	No	0	4	8
1193	S:S:F535	S:S:I534	7.54	Yes	Yes	9	6	8
1194	S:S:F721	S:S:I534	2.51	Yes	Yes	9	7	8
1195	S:S:A725	S:S:I534	1.62	No	Yes	0	6	8
1196	S:S:L536	S:S:R556	6.07	No	Yes	0	6	7
1197	S:S:F537	S:S:R556	20.31	No	Yes	0	5	7
1198	S:S:F537	S:S:F721	2.14	No	Yes	0	5	7
1199	S:S:F721	S:S:G538	4.52	Yes	No	0	7	7
1200	S:S:D540	S:S:L539	13.57	Yes	No	15	8	5
1201	S:S:F549	S:S:L539	2.44	Yes	No	15	4	5
1202	S:S:L539	S:S:R556	3.64	No	Yes	0	5	7
1203	S:S:D540	S:S:G541	1.68	Yes	Yes	15	8	5
1204	S:S:D540	S:S:V544	8.76	Yes	No	15	8	5
1205	S:S:D540	S:S:F549	8.36	Yes	Yes	15	8	4
1206	S:S:G541	S:S:V544	1.84	Yes	No	15	5	5
1207	S:S:F543	S:S:S542	3.96	No	No	0	4	4
1208	S:S:E546	S:S:V544	2.85	No	No	0	1	5
1209	S:S:E546	S:S:T548	15.52	No	No	0	1	2
1210	S:S:K547	S:S:R623	7.43	No	Yes	0	1	6
1211	S:S:T548	S:S:T551	10.99	No	No	0	2	1
1212	S:S:C553	S:S:F549	5.59	Yes	Yes	15	9	4
1213	S:S:F549	S:S:R623	3.21	Yes	Yes	0	4	6
1214	S:S:C648	S:S:F549	4.19	No	Yes	15	9	4
1215	S:S:E550	S:S:L621	5.3	No	Yes	0	3	6
1216	S:S:E550	S:S:R623	3.49	No	Yes	0	3	6
1217	S:S:L552	S:S:T551	4.42	No	No	0	4	1
1218	S:S:L552	S:S:R556	2.43	No	Yes	0	4	7
1219	S:S:C553	S:S:R556	13.93	Yes	Yes	0	9	7
1220	S:S:C553	S:S:L621	1.59	Yes	Yes	0	9	6
1221	S:S:C553	S:S:C648	1.82	Yes	No	15	9	9
1222	S:S:T554	S:S:V555	3.17	No	No	0	5	6
1223	S:S:L621	S:S:T554	5.9	Yes	No	0	6	5
1224	S:S:V555	S:S:W558	2.45	No	No	0	6	6
1225	S:S:L612	S:S:W558	4.56	No	No	0	7	6
1226	S:S:T561	S:S:V562	3.17	Yes	No	13	7	6
1227	S:S:D608	S:S:T561	5.78	No	Yes	13	9	7
1228	S:S:G563	S:S:V562	3.68	No	No	13	9	6
1229	S:S:D608	S:S:V562	5.84	No	No	13	9	6
1230	S:S:G563	S:S:T566	1.82	No	Yes	13	9	7
1231	S:S:F568	S:S:Y564	12.38	Yes	No	29	8	9
1232	S:S:K664	S:S:Y564	13.14	No	No	0	9	9
1233	S:S:M668	S:S:Y564	4.79	No	No	29	8	9
1234	S:S:K664	S:S:T565	10.51	No	No	0	9	8
1235	S:S:A567	S:S:T566	1.68	No	Yes	13	7	7
1236	S:S:F568	S:S:F572	11.79	Yes	Yes	29	8	9
1237	S:S:F568	S:S:L667	6.09	Yes	No	29	8	8
1238	S:S:F568	S:S:M668	2.49	Yes	No	29	8	8
1239	S:S:F568	S:S:V696	3.93	Yes	No	0	8	9
1240	S:S:F572	S:S:M571	6.22	Yes	No	0	9	8
1241	S:S:F572	S:S:L667	4.87	Yes	No	29	9	8
1242	S:S:F572	S:S:G671	6.02	Yes	No	0	9	9
1243	S:S:A573	S:S:L597	3.15	No	Yes	0	7	8
1244	S:S:L674	S:S:T575	5.9	No	No	0	9	9
1245	S:S:S689	S:S:T575	1.6	No	No	0	9	9
1246	S:S:L674	S:S:W576	4.56	No	No	0	9	8
1247	S:S:K593	S:S:R577	2.48	No	No	0	6	9
1248	S:S:E677	S:S:H579	13.54	No	No	0	9	8
1249	S:S:H579	S:S:T678	2.74	No	Yes	63	8	9
1250	S:S:H579	S:S:V681	4.15	No	No	63	8	8
1251	S:S:I592	S:S:Q595	8.23	No	No	0	7	4
1252	S:S:I600	S:S:M604	2.92	No	No	0	5	6
1253	S:S:M604	S:S:V601	3.04	No	No	0	6	7
1254	S:S:G602	S:S:G603	2.11	No	No	0	1	3
1255	S:S:G602	S:S:L605	5.13	No	No	0	1	5
1256	S:S:L605	S:S:L609	4.15	No	No	0	5	4
1257	S:S:I607	S:S:Y663	20.55	No	No	0	6	5
1258	S:S:D608	S:S:L612	5.43	No	No	0	9	7
1259	S:S:C614	S:S:I611	1.64	No	No	0	4	6
1260	S:S:I611	S:S:V660	3.07	No	No	0	6	5
1261	S:S:I613	S:S:Q616	6.86	No	No	0	4	6
1262	S:S:C614	S:S:W656	3.92	No	Yes	0	4	8
1263	S:S:P620	S:S:W615	10.81	Yes	No	0	9	9
1264	S:S:N650	S:S:W615	10.17	No	No	64	8	9
1265	S:S:W615	S:S:W656	14.06	No	Yes	64	9	8
1266	S:S:P620	S:S:Q616	9.47	Yes	No	0	9	6
1267	S:S:D619	S:S:V618	5.84	No	No	65	9	4
1268	S:S:R622	S:S:V618	2.62	Yes	No	65	4	4
1269	S:S:D619	S:S:P620	1.61	No	Yes	0	9	9
1270	S:S:D619	S:S:R622	15.48	No	Yes	65	9	4
1271	S:S:L621	S:S:P620	8.21	Yes	Yes	0	6	9
1272	S:S:R622	S:S:T651	15.52	Yes	No	0	4	2
1273	S:S:E646	S:S:R623	12.79	No	Yes	0	6	6
1274	S:S:L644	S:S:V625	2.98	No	No	0	4	4
1275	S:S:E646	S:S:V625	8.56	No	No	0	6	4
1276	S:S:E626	S:S:Y628	7.86	No	Yes	0	4	4
1277	S:S:K627	S:S:R642	7.43	No	Yes	0	3	4
1278	S:S:K627	S:S:L644	5.64	No	No	0	3	4
1279	S:S:E631	S:S:Y628	2.24	Yes	Yes	23	5	4
1280	S:S:P643	S:S:Y628	9.74	No	Yes	23	4	4
1281	S:S:L645	S:S:Y628	5.86	No	Yes	23	5	4
1282	S:S:E631	S:S:S629	14.37	Yes	No	0	5	1
1283	S:S:M630	S:S:P632	3.35	No	Yes	0	1	2
1284	S:S:M630	S:S:R642	16.13	No	Yes	0	1	4
1285	S:S:E631	S:S:P632	7.86	Yes	Yes	23	5	2
1286	S:S:E631	S:S:P643	3.14	Yes	No	23	5	4
1287	S:S:P632	S:S:P634	1.95	Yes	No	0	2	1
1288	S:S:I641	S:S:P632	1.69	Yes	Yes	0	5	2
1289	S:S:P632	S:S:P643	13.64	Yes	No	23	2	4
1290	S:S:D633	S:S:P634	1.61	No	No	0	3	1
1291	S:S:A635	S:S:G636	1.95	No	No	34	1	5
1292	S:S:A635	S:S:R637	2.77	No	No	34	1	3
1293	S:S:A635	S:S:I639	3.25	No	Yes	34	1	4
1294	S:S:G636	S:S:R637	3	No	No	34	5	3
1295	S:S:I639	S:S:R637	2.51	Yes	No	34	4	3
1296	S:S:I639	S:S:I641	4.42	Yes	Yes	0	4	5
1297	S:S:H647	S:S:R714	27.08	No	No	0	5	3
1298	S:S:H652	S:S:N650	8.93	No	No	0	4	8
1299	S:S:N650	S:S:W656	12.43	No	Yes	64	8	8
1300	S:S:H652	S:S:T651	2.74	No	No	0	4	2
1301	S:S:F711	S:S:T654	2.59	No	No	0	5	4
1302	S:S:I655	S:S:W656	5.87	No	Yes	0	5	8
1303	S:S:G658	S:S:L657	1.71	No	No	0	4	5
1304	S:S:F711	S:S:L657	4.87	No	No	0	5	5
1305	S:S:G658	S:S:Y661	2.9	No	No	0	4	6
1306	S:S:C703	S:S:Y661	2.69	No	No	0	7	6
1307	S:S:A707	S:S:Y661	5.34	No	No	0	6	6
1308	S:S:K664	S:S:Y663	9.55	No	No	0	9	5
1309	S:S:G665	S:S:M668	5.24	No	No	0	8	8
1310	S:S:A675	S:S:C672	3.61	No	No	0	9	5
1311	S:S:A675	S:S:T678	1.68	No	Yes	0	9	9
1312	S:S:R679	S:S:W676	4	No	No	0	9	8
1313	S:S:T678	S:S:V681	1.59	Yes	No	63	9	8
1314	S:S:S689	S:S:T678	7.99	No	Yes	0	9	9
1315	S:S:I683	S:S:V681	4.61	No	No	0	7	8
1316	S:S:P684	S:S:S682	1.78	No	No	0	6	6
1317	S:S:I683	S:S:P684	1.69	No	No	0	7	6
1318	S:S:L686	S:S:N687	5.49	No	No	0	8	9
1319	S:S:D688	S:S:N687	9.42	No	No	0	9	9
1320	S:S:D688	S:S:Y691	12.64	No	Yes	0	9	6
1321	S:S:I692	S:S:S689	3.1	No	No	0	8	9
1322	S:S:K690	W:W:?902	4.13	No	Yes	0	8	0
1323	S:S:P742	S:S:Y691	11.13	No	Yes	10	9	6
1324	S:S:Y691	W:W:?902	12.6	Yes	Yes	10	6	0
1325	S:S:G693	S:S:I692	1.76	No	No	0	7	8
1326	S:S:I692	S:S:S695	3.1	No	No	0	8	8
1327	S:S:G693	S:S:V696	3.68	No	No	0	7	9
1328	S:S:M694	W:W:?902	13.81	No	Yes	10	6	0
1329	S:S:S695	S:S:V696	3.23	No	No	0	8	9
1330	S:S:S695	S:S:T735	3.2	No	No	0	8	8
1331	S:S:I701	S:S:Y697	3.63	No	No	0	6	9
1332	S:S:M702	S:S:N698	7.01	Yes	No	0	7	9
1333	S:S:G700	S:S:V699	1.84	No	No	0	5	9
1334	S:S:C731	S:S:V699	5.12	No	No	0	7	9
1335	S:S:F730	S:S:M702	2.49	No	Yes	0	4	7
1336	S:S:C731	S:S:M702	1.62	No	Yes	0	7	7
1337	S:S:G706	S:S:I705	3.53	No	No	0	7	6
1338	S:S:A708	S:S:V709	1.7	No	No	0	5	6
1339	S:S:F711	S:S:S710	7.93	No	No	0	5	7
1340	S:S:Q720	S:S:R714	9.35	No	No	0	5	3
1341	S:S:D715	S:S:Q716	2.61	No	No	0	5	5
1342	S:S:N718	S:S:V719	4.43	No	No	0	7	6
1343	S:S:C722	S:S:I723	3.27	No	No	0	5	5
1344	S:S:C722	S:S:L726	1.59	No	No	0	5	4
1345	S:S:I728	S:S:V727	3.07	No	No	0	8	5
1346	S:S:I729	S:S:T733	3.04	No	Yes	0	6	8
1347	S:S:S732	S:S:T733	4.8	No	Yes	9	8	8
1348	S:S:I734	S:S:T733	3.04	No	Yes	0	4	8
1349	S:S:F740	S:S:L736	7.31	Yes	No	0	9	7
1350	S:S:C737	S:S:V741	1.71	No	Yes	10	4	6
1351	S:S:L738	W:W:?902	2.7	No	Yes	0	7	0
1352	S:S:F740	S:S:V739	3.93	Yes	No	0	9	8
1353	S:S:P742	S:S:V741	3.53	No	Yes	10	9	6
1354	S:S:I745	S:S:V741	3.07	No	Yes	10	3	6
1355	S:S:I745	S:S:P742	1.69	No	No	10	3	9
1356	R:R:P183	R:R:Q186	1.58	No	No	0	4	4
1357	R:R:A310	R:R:L354	1.58	No	No	0	8	8
1358	R:R:A575	R:R:L579	1.58	No	No	0	4	3
1359	R:R:A642	R:R:L669	1.58	No	Yes	0	3	5
1360	R:R:A643	R:R:L669	1.58	No	Yes	0	8	5
1361	S:S:P717	S:S:Q716	1.58	No	No	0	5	5
1362	S:S:P717	S:S:Q720	1.58	No	No	0	5	5
1363	S:S:A725	S:S:L726	1.58	No	No	0	6	4
1364	S:S:T159	S:S:T160	1.57	No	Yes	0	7	8
1365	S:S:E436	S:S:P287	1.57	No	No	0	4	2
1366	S:S:E462	S:S:P463	1.57	No	No	0	3	5
1367	S:S:T557	S:S:T561	1.57	No	Yes	0	4	7
1368	R:R:A397	R:R:N399	1.56	No	No	0	4	4
1369	R:R:A433	R:R:N434	1.56	No	No	0	3	4
1370	R:R:I841	R:R:S838	1.55	Yes	No	0	7	7
1371	R:R:I240	R:R:V170	1.54	No	No	0	5	8
1372	R:R:A359	R:R:D358	1.54	No	No	0	8	9
1373	R:R:I730	R:R:V731	1.54	No	No	0	4	4
1374	R:R:I818	R:R:V814	1.54	No	No	0	7	6
1375	R:R:I847	R:R:V850	1.54	No	No	0	4	5
1376	S:S:I659	S:S:V660	1.54	No	No	0	4	5
1377	S:S:I705	S:S:V709	1.54	No	No	0	6	6
1378	S:S:I728	S:S:V724	1.54	No	No	0	8	4
1379	R:R:K373	R:R:S345	1.53	No	No	0	5	5
1380	S:S:K276	S:S:S275	1.53	No	No	0	7	5
1381	S:S:K325	S:S:S323	1.53	No	No	0	3	6
1382	S:S:K547	S:S:S545	1.53	No	No	0	1	6
1383	R:R:I550	R:R:T565	1.52	Yes	No	0	7	3
1384	S:S:K70	S:S:V68	1.52	No	No	0	3	2
1385	S:S:M423	S:S:V445	1.52	No	No	0	5	1
1386	S:S:I456	S:S:T455	1.52	Yes	No	0	4	1
1387	S:S:M702	S:S:V727	1.52	Yes	No	0	7	5
1388	R:R:A333	R:R:E302	1.51	No	No	0	5	5
1389	R:R:F674	R:R:G671	1.51	No	No	0	9	6
1390	S:S:A164	S:S:E421	1.51	No	No	0	8	7
1391	S:S:F572	S:S:G569	1.51	Yes	No	0	9	9
1392	R:R:L175	R:R:S218	1.5	No	No	0	6	8
1393	R:R:L495	R:R:S485	1.5	No	No	0	7	4
1394	R:R:L591	R:R:S588	1.5	No	No	0	6	7
1395	R:R:G655	R:R:R656	1.5	No	No	0	5	1
1396	R:R:L676	R:R:S675	1.5	No	No	0	7	9
1397	R:R:L211	R:R:V170	1.49	No	No	0	9	8
1398	R:R:L229	R:R:V253	1.49	No	No	0	7	7
1399	R:R:L252	R:R:V253	1.49	No	No	0	5	7
1400	R:R:L326	R:R:V330	1.49	No	No	0	8	7
1401	R:R:L383	R:R:V378	1.49	Yes	Yes	7	7	8
1402	R:R:L839	R:R:V595	1.49	No	Yes	0	3	6
1403	R:R:L815	R:R:V814	1.49	No	No	0	7	6
1404	S:S:L243	S:S:V248	1.49	No	No	0	8	7
1405	S:S:N718	S:S:S478	1.49	No	No	0	7	6
1406	S:S:L686	S:S:V578	1.49	No	No	0	8	9
1407	R:R:N811	R:R:V812	1.48	No	No	0	8	8
1408	R:R:L292	R:R:T291	1.47	No	No	0	5	6
1409	R:R:L481	R:R:T484	1.47	No	No	0	8	8
1410	R:R:I818	S:S:I705	1.47	No	No	0	7	6
1411	R:R:L826	S:S:T713	1.47	No	No	0	6	6
1412	S:S:L376	S:S:T375	1.47	No	No	0	7	1
1413	S:S:L511	S:S:T746	1.47	Yes	No	61	4	4
1414	S:S:L522	S:S:T566	1.47	No	Yes	0	5	7
1415	S:S:L560	S:S:T561	1.47	No	Yes	0	7	7
1416	S:S:L712	S:S:T713	1.47	No	No	0	6	6
1417	S:S:L747	S:S:T746	1.47	No	No	61	6	4
1418	R:R:N767	R:R:T768	1.46	No	No	0	4	5
1419	S:S:I251	S:S:M272	1.46	No	No	0	9	7
1420	S:S:N389	S:S:T391	1.46	No	No	0	5	4
1421	R:R:I408	R:R:K373	1.45	Yes	No	0	3	5
1422	R:R:D721	R:R:T724	1.45	Yes	No	0	9	6
1423	R:R:G775	R:R:Y774	1.45	No	No	0	4	6
1424	S:S:G221	S:S:Y220	1.45	No	No	0	3	5
1425	S:S:G274	S:S:Y273	1.45	No	No	0	8	5
1426	S:S:I592	S:S:K596	1.45	No	No	0	7	6
1427	R:R:K386	R:R:K387	1.44	No	Yes	0	5	6
1428	R:R:F659	R:R:P660	1.44	Yes	No	0	4	3
1429	S:S:E286	S:S:S288	1.44	No	No	0	4	3
1430	R:R:I474	R:R:L196	1.43	No	No	0	6	6
1431	R:R:I825	R:R:L826	1.43	No	No	0	6	6
1432	S:S:E67	S:S:V68	1.43	No	No	0	1	2
1433	S:S:I729	S:S:L488	1.43	No	No	0	6	4
1434	S:S:I600	S:S:L597	1.43	No	Yes	0	5	8
1435	R:R:G305	R:R:W306	1.41	No	Yes	0	4	9
1436	R:R:E336	S:S:T238	1.41	No	No	0	6	3
1437	R:R:T338	S:S:E230	1.41	No	No	0	4	8
1438	R:R:L717	R:R:M720	1.41	No	No	0	6	6
1439	R:R:K743	R:R:L755	1.41	No	Yes	0	1	4
1440	S:S:L511	S:S:M514	1.41	Yes	No	0	4	7
1441	S:S:K596	S:S:L597	1.41	No	Yes	0	6	8
1442	S:S:K743	S:S:L744	1.41	No	No	0	9	5
1443	S:S:K305	S:S:N306	1.4	No	No	0	4	6
1444	S:S:D594	S:S:I592	1.4	No	No	0	8	7
1445	R:R:H618	R:R:S617	1.39	No	No	0	6	7
1446	R:R:C761	R:R:R736	1.39	No	No	0	9	5
1447	R:R:H760	R:R:S762	1.39	No	No	0	4	5
1448	R:R:L605	R:R:L849	1.38	No	Yes	0	4	8
1449	R:R:L639	R:R:L669	1.38	Yes	Yes	0	6	5
1450	R:R:L639	R:R:L672	1.38	Yes	No	0	6	5
1451	S:S:L146	S:S:L151	1.38	No	No	0	7	7
1452	S:S:L609	S:S:L612	1.38	No	No	0	4	7
1453	R:R:I423	R:R:Q541	1.37	No	No	0	6	9
1454	R:R:I550	R:R:Q541	1.37	Yes	No	0	7	9
1455	S:S:D105	S:S:L64	1.36	No	No	0	8	5
1456	R:R:P183	R:R:W182	1.35	No	Yes	0	4	6
1457	R:R:E336	R:R:K308	1.35	No	No	0	6	7
1458	R:R:E381	R:R:L383	1.33	No	Yes	0	5	7
1459	S:S:L598	S:S:Q595	1.33	No	No	0	5	4
1460	R:R:N434	R:R:Q444	1.32	No	No	0	4	4
1461	R:R:N502	R:R:Q503	1.32	No	Yes	14	7	3
1462	R:R:N657	R:R:Q658	1.32	No	No	0	1	3
1463	S:S:N150	S:S:Q147	1.32	No	No	0	8	6
1464	S:S:R577	S:S:S516	1.32	No	Yes	0	9	9
1465	R:R:R620	R:R:V619	1.31	No	No	0	8	5
1466	R:R:F659	R:R:V662	1.31	Yes	No	0	4	5
1467	S:S:E339	S:S:N343	1.31	No	No	0	2	3
1468	S:S:R435	S:S:V437	1.31	No	No	0	1	4
1469	S:S:E441	S:S:N443	1.31	No	No	0	4	4
1470	R:R:D497	R:R:E496	1.3	No	No	0	4	4
1471	S:S:A580	S:S:W576	1.3	No	No	0	6	8
1472	S:S:R622	S:S:T624	1.29	Yes	No	0	4	3
1473	R:R:E370	R:R:Q314	1.27	No	No	0	5	8
1474	R:R:F584	R:R:I738	1.26	No	No	0	4	4
1475	R:R:R356	S:S:I226	1.25	No	No	0	5	6
1476	R:R:I738	R:R:R736	1.25	No	No	0	4	5
1477	R:R:F612	R:R:M857	1.24	No	No	0	8	6
1478	R:R:V428	R:R:W536	1.23	No	No	0	5	3
1479	R:R:N657	R:R:R656	1.21	No	No	0	1	1
1480	R:R:L667	R:R:R666	1.21	Yes	No	0	5	8
1481	S:S:N344	S:S:R340	1.21	No	No	0	1	2
1482	S:S:L597	S:S:R577	1.21	Yes	No	0	8	9
1483	R:R:F586	R:R:Q589	1.17	No	No	0	4	2
1484	R:R:K709	R:R:W708	1.16	No	No	0	7	4
1485	S:S:F501	S:S:F502	1.07	No	No	0	1	6
1486	S:S:F670	S:S:F673	1.07	No	No	0	7	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:G173	2.474	5	0	7
2	R:R:F176	4.118	5	0	7
3	R:R:W182	5.732	5	0	6
4	R:R:R202	7.5225	4	5	5
5	R:R:I205	6.2675	4	5	6
6	R:R:Y209	7.0925	4	35	8
7	R:R:I214	3.6825	4	16	3
8	R:R:D221	5.535	4	6	6
9	R:R:G223	3.895	4	6	7
10	R:R:Y230	5.514	5	11	7
11	R:R:Y234	4.9	4	11	5
12	R:R:D236	8.605	4	16	3
13	R:R:P237	10.3625	4	16	6
14	R:R:K239	7.01	4	16	7
15	R:R:I241	4.025	4	0	7
16	R:R:M243	3.4325	4	0	7
17	R:R:P244	2.05	6	0	8
18	R:R:S248	2.1125	4	6	5
19	R:R:T251	2.6425	4	4	7
20	R:R:M259	3.405	4	11	5
21	R:R:W260	5.48	6	11	7
22	R:R:S266	2.385	4	4	8
23	R:R:G268	2.825	4	4	7
24	R:R:S269	4.1325	4	4	8
25	R:R:S271	3.864	5	4	9
26	R:R:L274	5.086	5	4	8
27	R:R:R279	9.1425	4	4	6
28	R:R:F280	10.52	4	4	8
29	R:R:F283	4.716	5	4	8
30	R:R:F284	5.19	6	24	6
31	R:R:R285	4.02	4	4	9
32	R:R:H293	4.91	4	0	5
33	R:R:R297	3.9375	4	12	7
34	R:R:W304	9.124	5	12	7
35	R:R:W306	3.72875	8	12	9
36	R:R:Q313	4.81	4	18	7
37	R:R:V318	8.355	4	4	5
38	R:R:F339	6.2925	4	19	6
39	R:R:R340	5.714	5	18	6
40	R:R:Q341	6.63	4	19	7
41	R:R:F344	4.0275	4	38	4
42	R:R:V349	3.5775	4	19	3
43	R:R:P350	5.3375	4	19	7
44	R:R:R372	7.03	4	3	7
45	R:R:F375	5.806	5	7	8
46	R:R:V378	2.46	5	7	8
47	R:R:Y379	11.86	4	3	7
48	R:R:L383	4.1075	4	7	7
49	R:R:F384	6.16	4	3	5
50	R:R:K387	7.58	4	7	6
51	R:R:F391	4.6375	4	12	7
52	R:R:I393	3.8375	4	0	5
53	R:R:Y396	3.35	4	0	5
54	R:R:W400	5.28667	6	0	8
55	R:R:D405	8.35	4	3	3
56	R:R:I408	8.1825	4	3	3
57	R:R:E414	9.125	4	3	7
58	R:R:H422	6.7025	4	26	6
59	R:R:S439	4.815	4	5	8
60	R:R:M441	3.322	5	5	5
61	R:R:F446	5.08	4	5	7
62	R:R:P468	2.3625	4	0	5
63	R:R:Y471	6.38429	7	5	9
64	R:R:D472	4.855	4	0	9
65	R:R:W475	6.56167	6	5	8
66	R:R:Y500	6.0575	4	11	8
67	R:R:Q503	5.64	4	14	3
68	R:R:S522	5.55	4	17	9
69	R:R:R533	6.6975	4	17	9
70	R:R:Y547	6.15333	6	26	5
71	R:R:I550	3.986	5	41	7
72	R:R:Y553	5.43167	6	25	6
73	R:R:D554	8.555	4	40	5
74	R:R:W562	11.6025	4	0	5
75	R:R:W568	7.215	4	12	9
76	R:R:P573	8.1325	4	12	5
77	R:R:T578	4.62	4	7	6
78	R:R:F592	5.595	4	20	5
79	R:R:V595	1.8325	4	20	6
80	R:R:N613	7.13	4	21	9
81	R:R:L639	2.8275	4	44	6
82	R:R:V644	2.6725	4	20	8
83	R:R:D650	7.7225	4	30	9
84	R:R:F659	5.89	4	0	4
85	R:R:Q664	5.3325	4	27	6
86	R:R:L667	5.32	4	27	5
87	R:R:L669	1.545	4	0	5
88	R:R:Y678	6.454	5	0	8
89	R:R:W687	5.7375	4	28	9
90	R:R:F692	7.275	4	28	8
91	R:R:V718	3.495	4	46	7
92	R:R:D721	3.405	4	45	9
93	R:R:Q729	14.6775	4	27	6
94	R:R:D732	5.7275	4	49	8
95	R:R:S753	2.4125	4	0	2
96	R:R:L755	4.78	4	0	4
97	R:R:L758	4.755	4	0	5
98	R:R:L787	2.8025	4	48	9
99	R:R:I809	5.3	4	47	8
100	R:R:I841	2.38	4	0	7
101	R:R:S844	2.4125	4	42	7
102	R:R:L849	2.978	5	0	8
103	R:R:F853	8.762	5	21	9
104	S:S:S53	5.265	4	0	4
105	S:S:P54	4.55	4	0	3
106	S:S:M59	8.75	4	51	7
107	S:S:P63	3.7	5	0	8
108	S:S:V77	2.134	5	1	5
109	S:S:L78	3.1675	4	0	4
110	S:S:Y97	7.568	5	50	8
111	S:S:N110	4.96	4	0	5
112	S:S:Y118	5.605	4	0	7
113	S:S:K122	5.58	4	11	4
114	S:S:H127	9.7375	4	0	8
115	S:S:F131	5.0225	4	54	7
116	S:S:P136	2.2675	4	52	9
117	S:S:Q153	5.4	4	8	9
118	S:S:S155	3.9275	4	8	8
119	S:S:T160	2.234	5	0	8
120	S:S:F172	4.2025	4	8	8
121	S:S:R174	7.345	4	8	9
122	S:S:N180	4.87	4	8	6
123	S:S:Y193	7.7375	4	55	8
124	S:S:W195	6.636	5	0	9
125	S:S:Q203	6.982	5	22	7
126	S:S:F208	8.62	4	22	7
127	S:S:R212	6.912	5	0	5
128	S:S:P236	6.4975	4	56	5
129	S:S:G253	2.8525	4	0	5
130	S:S:F255	3.51	4	22	8
131	S:S:D256	6.1525	4	22	7
132	S:S:F264	5.90667	6	2	7
133	S:S:Y268	7.084	5	58	6
134	S:S:Y277	9.2175	4	57	8
135	S:S:P282	5.1875	4	0	5
136	S:S:W284	5.37	5	0	6
137	S:S:Y285	6.6575	4	2	5
138	S:S:W289	7.53333	6	2	9
139	S:S:W290	7.51	5	2	6
140	S:S:M311	4.702	5	2	5
141	S:S:Y314	3.552	5	2	5
142	S:S:G316	2.44	5	0	5
143	S:S:D318	4.8125	4	0	6
144	S:S:F319	5.3325	4	1	4
145	S:S:S331	5.525	6	1	8
146	S:S:G332	3.9975	4	1	7
147	S:S:K333	8.7675	4	1	5
148	S:S:T334	7.6875	4	33	8
149	S:S:Q337	7.7	4	0	5
150	S:S:Y338	5.522	5	1	7
151	S:S:R346	6.605	4	1	4
152	S:S:H355	7.224	5	1	7
153	S:S:Y357	4.974	5	1	5
154	S:S:Y359	7.245	6	1	9
155	S:S:D360	4.35833	6	1	9
156	S:S:W363	7.868	5	1	8
157	S:S:H377	4.2775	4	0	1
158	S:S:Q386	8.6975	4	50	5
159	S:S:F388	4.5475	4	53	7
160	S:S:L395	6.4625	4	53	6
161	S:S:M403	6.435	4	31	5
162	S:S:V411	4.308	5	1	7
163	S:S:T412	5.832	5	1	9
164	S:S:R422	7.026	5	1	9
165	S:S:F428	3.7025	4	32	8
166	S:S:Q430	4.3725	4	0	9
167	S:S:F431	9.064	5	2	5
168	S:S:G440	1.745	4	0	7
169	S:S:Y442	5.48833	6	32	6
170	S:S:I456	3.2875	4	55	4
171	S:S:R457	10.575	4	2	1
172	S:S:T468	3.7575	4	0	6
173	S:S:P480	4.19	4	0	3
174	S:S:L481	5.47	4	9	5
175	S:S:T489	4.59	5	9	7
176	S:S:L511	3.584	5	61	4
177	S:S:S516	3.63	5	62	9
178	S:S:G526	1.90167	6	13	9
179	S:S:Y531	4.094	5	9	8
180	S:S:I534	3.512	5	9	8
181	S:S:F535	5.1825	4	9	6
182	S:S:D540	8.0925	4	15	8
183	S:S:G541	1.7425	4	15	5
184	S:S:F549	4.758	5	15	4
185	S:S:C553	5.7325	4	15	9
186	S:S:R556	9.276	5	0	7
187	S:S:T561	2.9975	4	13	7
188	S:S:T566	1.6975	4	13	7
189	S:S:F568	7.336	5	29	8
190	S:S:F572	6.082	5	29	9
191	S:S:L597	1.8	4	0	8
192	S:S:P620	7.525	4	0	9
193	S:S:L621	5.25	4	0	6
194	S:S:R622	8.7275	4	65	4
195	S:S:R623	6.73	4	0	6
196	S:S:Y628	6.168	5	23	4
197	S:S:E631	6.9025	4	23	5
198	S:S:P632	5.698	5	23	2
199	S:S:I639	5.8575	4	34	4
200	S:S:I641	6.0425	4	0	5
201	S:S:R642	9.2	4	60	4
202	S:S:W656	9.07	4	64	8
203	S:S:T678	3.5	4	63	9
204	S:S:Y691	9.9875	4	10	6
205	S:S:M702	3.16	4	0	7
206	S:S:F721	3.78667	6	9	7
207	S:S:T733	3.345	4	9	8
208	S:S:F740	6.23	4	0	9
209	S:S:V741	2.7325	4	10	6
210	W:W:?902	7.29	8	10	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G173	R:R:L242	10.0721	1.71	Yes	No	0	7	6
2	R:R:L242	R:R:P244	10.3057	1.64	No	Yes	0	6	8
3	R:R:P244	R:R:S266	13.5199	1.78	Yes	Yes	0	8	8
4	R:R:G268	R:R:S266	23.8971	1.86	Yes	Yes	4	7	8
5	R:R:P244	R:R:V264	11.5887	3.53	Yes	No	0	8	9
6	R:R:F283	R:R:V264	11.6997	5.24	Yes	No	0	8	9
7	R:R:F283	R:R:L274	45.7395	8.53	Yes	Yes	4	8	8
8	R:R:F283	R:R:S266	34.0852	2.64	Yes	Yes	4	8	8
9	R:R:F280	R:R:L274	66.4212	7.31	Yes	Yes	4	8	8
10	R:R:E255	R:R:F280	66.4235	8.16	No	Yes	4	8	8
11	R:R:E255	S:S:N110	67.2118	5.26	No	Yes	0	8	5
12	R:R:G268	R:R:H287	18.0656	4.77	Yes	No	0	7	7
13	R:R:H293	R:R:I427	11.1141	6.63	Yes	No	0	5	5
14	R:R:I427	R:R:P288	10.696	1.69	No	No	36	5	6
15	R:R:H287	R:R:P288	17.9458	9.15	No	No	0	7	6
16	R:R:R285	R:R:S289	11.0838	6.59	Yes	No	0	9	8
17	R:R:S289	R:R:T291	10.429	1.6	No	No	0	8	6
18	R:R:D325	R:R:T291	10.1735	5.78	No	No	0	6	6
19	R:R:H293	R:R:R297	10.6164	4.51	Yes	Yes	0	5	7
20	R:R:W304	R:R:W306	13.5409	5.62	Yes	Yes	12	7	9
21	R:R:P350	R:R:V351	25.8999	1.77	Yes	No	0	7	8
22	R:R:V351	R:R:V378	25.8299	1.6	No	Yes	0	8	8
23	R:R:F375	R:R:V378	13.3414	3.93	Yes	Yes	7	8	8
24	R:R:F375	R:R:W400	11.7207	2	Yes	Yes	0	8	8
25	S:S:N110	S:S:S137	56.9495	5.96	Yes	No	0	5	4
26	S:S:P136	S:S:S137	56.9979	3.56	Yes	No	0	9	4
27	S:S:P136	S:S:T160	57.4028	1.75	Yes	Yes	0	9	8
28	R:R:P350	R:R:V349	25.8527	3.53	Yes	Yes	19	7	3
29	R:R:V349	S:S:T216	26.2965	3.17	Yes	No	0	3	5
30	R:R:L383	R:R:V378	18.1618	1.49	Yes	Yes	7	7	8
31	R:R:L383	R:R:Y388	17.6205	9.38	Yes	No	7	7	8
32	R:R:K387	R:R:Y388	17.4923	8.36	Yes	No	7	6	8
33	R:R:S753	R:R:T578	15.1409	1.6	Yes	Yes	0	2	6
34	R:R:S753	R:R:V580	13.4676	1.62	Yes	No	0	2	4
35	R:R:L755	R:R:V580	13.1891	10.43	Yes	No	0	4	4
36	R:R:K582	R:R:L755	12.3596	5.64	No	Yes	0	1	4
37	R:R:K582	R:R:Q757	12.0807	17.63	No	No	0	1	5
38	R:R:I738	R:R:Q757	11.5227	6.86	No	No	0	4	5
39	R:R:I738	R:R:R736	10.9642	1.25	No	No	0	4	5
40	S:S:P161	S:S:T160	57.3106	1.75	No	Yes	0	6	8
41	S:S:N180	S:S:P161	57.3078	6.52	Yes	No	8	6	6
42	S:S:N180	S:S:V211	63.9138	2.96	Yes	No	0	6	6
43	S:S:Q254	S:S:V211	63.9845	2.87	No	No	0	6	6
44	S:S:G253	S:S:Q254	31.6179	4.93	Yes	No	0	5	6
45	S:S:F255	S:S:G253	31.2617	3.01	Yes	Yes	0	8	5
46	S:S:F255	S:S:V263	31.4067	6.55	Yes	No	0	8	7
47	S:S:F264	S:S:V263	31.4507	10.49	Yes	No	0	7	7
48	S:S:F264	S:S:W279	31.2735	12.03	Yes	No	0	7	9
49	S:S:I251	S:S:W279	100	19.97	No	No	0	9	9
50	S:S:I251	S:S:M272	99.9273	1.46	No	No	0	9	7
51	S:S:M272	S:S:Y277	99.5133	9.58	No	Yes	57	7	8
52	S:S:K276	S:S:Y277	99.489	20.3	No	Yes	0	7	8
53	S:S:K276	S:S:R249	99.2687	4.95	No	No	0	7	9
54	S:S:R249	S:S:T468	99.195	2.59	No	Yes	0	9	6
55	S:S:I470	S:S:T468	97.9288	3.04	No	Yes	0	3	6
56	S:S:I470	S:S:R642	97.7384	6.26	No	Yes	60	3	4
57	S:S:K627	S:S:R642	95.7845	7.43	No	Yes	0	3	4
58	S:S:K627	S:S:L644	95.7066	5.64	No	No	0	3	4
59	S:S:L644	S:S:V625	95.6286	2.98	No	No	0	4	4
60	S:S:E646	S:S:V625	95.5504	8.56	No	No	0	6	4
61	S:S:E646	S:S:R623	95.4722	12.79	No	Yes	0	6	6
62	S:S:F549	S:S:R623	78.6847	3.21	Yes	Yes	0	4	6
63	S:S:F549	S:S:L539	38.8397	2.44	Yes	No	15	4	5
64	S:S:L539	S:S:R556	38.831	3.64	No	Yes	0	5	7
65	S:S:F537	S:S:R556	78.8972	20.31	No	Yes	0	5	7
66	S:S:F537	S:S:F721	78.6719	2.14	No	Yes	0	5	7
67	S:S:F721	S:S:I534	72.0271	2.51	Yes	Yes	9	7	8
68	S:S:I534	S:S:T489	69.5553	3.04	Yes	Yes	9	8	7
69	S:S:T489	S:S:Y531	68.9347	7.49	Yes	Yes	9	7	8
70	S:S:G492	S:S:Y531	66.8783	4.35	No	Yes	0	8	8
71	S:S:G492	S:S:M495	66.4173	3.49	No	No	0	8	4
72	S:S:C737	S:S:M495	66.1867	1.62	No	No	0	4	4
73	S:S:C737	S:S:V741	54.7605	1.71	No	Yes	10	4	6
74	S:S:P742	S:S:V741	54.7617	3.53	No	Yes	10	9	6
75	S:S:P742	S:S:Y691	54.5368	11.13	No	Yes	10	9	6
76	R:R:K792	S:S:Y691	49.4247	3.58	No	Yes	10	9	6
77	R:R:K792	R:R:S793	49.3369	3.06	No	No	0	9	7
78	R:R:S793	R:R:V794	49.0995	1.62	No	No	0	7	8
79	R:R:T796	R:R:V794	48.3867	1.59	No	No	0	7	8
80	R:R:F692	R:R:T796	47.902	14.27	Yes	No	28	8	7
81	R:R:F692	R:R:W687	47.179	2	Yes	Yes	28	8	9
82	R:R:W686	R:R:W687	41.6865	5.62	No	Yes	0	8	9
83	R:R:F682	R:R:W686	41.4606	2	No	No	0	9	8
84	R:R:F682	R:R:Y678	39.98	2.06	No	Yes	0	9	8
85	R:R:M681	R:R:Y678	38.0494	3.59	No	Yes	0	9	8
86	R:R:I809	R:R:M681	37.8079	11.66	Yes	No	0	8	9
87	R:R:I809	R:R:V805	37.3518	3.07	Yes	No	47	8	9
88	R:R:D801	R:R:V805	37.1167	2.92	No	No	0	9	9
89	R:R:D801	R:R:S625	36.6321	4.42	No	No	0	9	9
90	R:R:K856	R:R:S625	34.8944	4.59	No	No	0	9	9
91	R:R:F853	R:R:K856	34.6517	4.96	Yes	No	0	9	9
92	R:R:F853	R:R:L852	32.2066	8.53	Yes	No	21	9	7
93	R:R:L849	R:R:L852	32.0106	2.77	Yes	No	0	8	7
94	R:R:C637	R:R:L849	15.5143	1.59	No	Yes	0	5	8
95	R:R:C637	R:R:S844	12.7642	1.72	No	Yes	42	5	7
96	R:R:I841	R:R:S844	25.078	3.1	Yes	Yes	0	7	7
97	R:R:I841	R:R:S838	11.063	1.55	Yes	No	0	7	7
98	S:S:P282	S:S:Q254	33.0792	7.9	Yes	No	0	5	6
99	S:S:G283	S:S:P282	32.3822	2.03	No	Yes	0	6	5
100	S:S:G283	S:S:G316	50.231	2.11	No	Yes	0	6	5
101	S:S:G316	S:S:Y314	69.2289	2.9	Yes	Yes	0	5	5
102	S:S:W279	S:S:Y314	69.416	2.89	No	Yes	0	9	5
103	S:S:C553	S:S:F549	38.8859	5.59	Yes	Yes	15	9	4
104	S:S:C553	S:S:R556	40.9553	13.93	Yes	Yes	0	9	7
105	R:R:L849	R:R:T848	15.7645	4.42	Yes	No	0	8	8
106	R:R:S844	R:R:T848	12.7959	3.2	Yes	No	0	7	8
107	S:S:N110	S:S:V138	10.4027	2.96	Yes	No	0	5	8
108	S:S:T139	S:S:V138	10.4085	1.59	No	No	0	8	8
109	S:S:G133	S:S:T139	10.2924	1.82	No	No	0	6	8
110	S:S:D318	S:S:G283	18.7159	6.71	Yes	No	0	6	6
111	S:S:D318	S:S:F319	18.6304	4.78	Yes	Yes	0	6	4
112	S:S:F319	S:S:Y357	18.2928	5.16	Yes	Yes	1	4	5
113	S:S:T412	S:S:Y357	17.1759	6.24	Yes	Yes	1	9	5
114	S:S:R212	S:S:T216	26.4042	5.17	Yes	No	0	5	5
115	S:S:L215	S:S:R212	13.3664	3.64	No	Yes	0	8	5
116	S:S:L215	S:S:N183	13.4728	13.73	No	No	0	8	9
117	S:S:N183	S:S:P184	13.5803	1.63	No	No	0	9	4
118	S:S:P184	S:S:Y442	13.6195	5.56	No	Yes	0	4	6
119	S:S:G316	S:S:V317	14.0438	1.84	Yes	No	0	5	6
120	S:S:F428	S:S:V317	13.977	3.93	Yes	No	0	8	6
121	S:S:I226	S:S:R212	14.5348	3.76	No	Yes	0	6	5
122	S:S:I226	S:S:V198	14.6135	6.14	No	No	0	6	8
123	S:S:I250	S:S:V198	14.6926	3.07	No	No	0	9	8
124	S:S:I250	S:S:W195	14.7329	5.87	No	Yes	0	9	9
125	S:S:G316	S:S:I315	14.3339	3.53	Yes	No	0	5	5
126	S:S:I315	S:S:Q278	14.2701	2.74	No	No	0	5	8
127	S:S:C737	S:S:F499	11.1954	2.79	No	No	10	4	7
128	S:S:F499	S:S:F740	11.4255	6.43	No	Yes	0	7	9
129	S:S:E550	S:S:R623	16.5533	3.49	No	Yes	0	3	6
130	S:S:E550	S:S:L621	16.4584	5.3	No	Yes	0	3	6
131	S:S:L621	S:S:T554	16.4165	5.9	Yes	No	0	6	5
132	S:S:T554	S:S:V555	16.2887	3.17	No	No	0	5	6
133	S:S:V555	S:S:W558	16.1609	2.45	No	No	0	6	6
134	S:S:L612	S:S:W558	16.0329	4.56	No	No	0	7	6
135	S:S:D608	S:S:L612	15.3916	5.43	No	No	0	9	7
136	S:S:D608	S:S:V562	14.8614	5.84	No	No	13	9	6
137	S:S:G563	S:S:V562	14.748	3.68	No	No	13	9	6
138	S:S:A567	S:S:I523	13.1665	4.87	No	No	0	7	8
139	S:S:I523	S:S:M571	12.6335	4.37	No	No	0	8	8
140	S:S:F572	S:S:M571	12.3668	6.22	Yes	No	0	9	8
141	S:S:F568	S:S:F572	11.2973	11.79	Yes	Yes	29	8	9
142	S:S:F428	S:S:Y442	13.7711	3.09	Yes	Yes	32	8	6
143	S:S:Q278	S:S:W195	14.2213	4.38	No	Yes	0	8	9
144	R:R:M243	R:R:P244	10.1581	1.68	Yes	Yes	0	7	8
145	R:R:L274	R:R:R285	11.2143	3.64	Yes	Yes	4	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I785	W:W:?902	2.79	0	No	Yes	6	0	1	0
R:R:A788	W:W:?902	4.62	0	No	Yes	9	0	1	0
R:R:K792	R:R:S793	3.06	10	No	No	9	7	1	2
R:R:K792	S:S:Y691	3.58	10	No	Yes	9	6	1	1
R:R:K792	W:W:?902	9.65	10	No	Yes	9	0	1	0
R:R:Y810	S:S:M694	3.59	10	No	No	9	6	1	1
R:R:Y810	S:S:N698	5.81	10	No	No	9	9	1	2
R:R:Y810	W:W:?902	8.02	10	No	Yes	9	0	1	0
S:S:D688	S:S:Y691	12.64	0	No	Yes	9	6	2	1
S:S:K690	W:W:?902	4.13	0	No	Yes	8	0	1	0
S:S:P742	S:S:Y691	11.13	10	No	Yes	9	6	2	1
S:S:Y691	W:W:?902	12.6	10	Yes	Yes	6	0	1	0
S:S:M694	W:W:?902	13.81	10	No	Yes	6	0	1	0
S:S:L738	W:W:?902	2.7	0	No	Yes	7	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
88.89	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
55.56	Single	7EB2	rac-BHFF	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
55.56	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
55.56	Consensus	gabab_on	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
55.56	Consensus	gi_class-c	Other Ligand	gi_mglu gi_gaba
50.00	Consensus	gi_gaba	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
43.75	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
37.50	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
31.58	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
31.25	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
30.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
28.57	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
26.67	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
26.32	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
25.00	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
25.00	Consensus	ffa3_on_allo	Other Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
23.53	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
23.08	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
23.08	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
22.22	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
21.43	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
21.43	Single	8HNN	SCH546738	8HNN-CXCR3-SCH546738
20.00	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
18.75	Single	7RBT	PubChem 163183774	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
11.76	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
11.11	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
10.00	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
9.09	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
7.14	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
6.25	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
5.88	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
5.88	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/&β;1/&γ;2
5.56	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
5.56	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
5.56	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
5.26	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/&β;1/&γ;2
4.76	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
4.76	Consensus	ccr9_off_allo	Other Ligand	5LWE-CCR9-Vercirnon
3.23	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
3.23	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
3.12	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
3.12	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
3.12	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
3.12	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
3.12	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
3.03	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
2.94	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
2.86	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
2.86	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
2.70	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.56	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
2.50	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
2.50	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
2.50	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.38	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2

PDB Summary
PDB	7CA3
Class	C
SubFamily	Aminoacid
Type	GABAB
SubType	GABAB1; GABAB2
Species	Homo sapiens
Ligand	-
Other Ligand(s)	rac-BHFF
Protein Partners	-
PDB Resolution	4.5
Date	2020-11-11
D.O.I.	10.1016/j.jmb.2020.09.023

Net Summary
I_min	1.59
Number of Linked Nodes	1265
Number of Links	1486
Number of Hubs	210
Number of Links mediated by Hubs	773
Number of Communities	65
Number of Nodes involved in Communities	360
Number of Links involved in Communities	454

Path Summary
Number Of Nodes in MetaPath	146
Number Of Links MetaPath	145
Number of Shortest Paths	3109084
Length Of Smallest Path	3
Average Path Length	48.1031
Length of Longest Path	97
Minimum Path Strength	1.255
Average Path Strength	5.47447
Maximum Path Strength	18.705
Minimum Path Correlation	0.7
Average Path Correlation	0.996765
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.47059
Average % Of Corr. Nodes	56.4479
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.9237
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	FN0
PDB Residues	W:W:?902
Environment Details	Open EMBL-EBI Page
Code	FN0
Name	(3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one
Synonyms
Identifier	(3~{S})-5,7-di~{tert}-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one
Formula	C17 H21 F3 O3
Molecular Weight	330.342
SMILES	CC(C)(C)c1cc2c(c(c1)C(C)(C)C)OC(=O)[C@@]2(C(F)(F)F)O
PubChem	7023848
Formal Charge	0
Total Atoms	44
Total Chiral Atoms	1
Total Bonds	45
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9UBS5
Sequence	>7CA3_Chain_R R R A V Y I G A L F P M S G G W P G G Q A C Q P A V E M A L E D V N S R R D I L P D Y E L K L I H H D S K C D P G Q A T K Y L Y E L L Y N D P I K I I L M P G C S S V S T L V A E A A R M W N L I V L S Y G S S S P A L S N R Q R F P T F F R T H P S A T L H N P T R V K L F E K W G W K K I A T I Q Q T T E V F T S T L D D L E E R V K E A G I E I T F R Q S F F S D P A V P V K N L K R Q D A R I I V G L F Y E T E A R K V F C E V Y K E R L F G K K Y V W F L I G W Y A D N W F K I Y D P S I N C T V D E M T E A V E G H I T T E I V M L N P A N T R S I S N M T S Q E F V E K L T K R L T G G F Q E A P L A Y D A I W A L A L A L N K T S R L E D F N Y N N Q T I T D Q I Y R A M N S S S F E G V S G H V V F D A S G S R M A W T L I E Q L Q G G S Y K K I G Y Y D S T K D D L S W S K T D K W I G G S P P A D Q T L V I K T F R F L S Q K L F I S V S V L S S L G I V L A V V C L S F N I Y N S H V R Y I Q N S Q P N L N N L T A V G C S L A L A A V F P L G L D G Y H I G R N Q F P F V C Q A R L W L L G L G F S L G Y G S M F T K I W W V H T V F T E P W K L Y A T V G L L V G M D V L T L A I W Q I V D P L H R T I E T F A K E E P K E D I D V S I L P Q L E H C S S R K M N T W L G I F Y G Y K G L L L L L G I F L A Y E T K S V S T E K I N D H R A V G M A I Y N V A V L C L I T A P V T M I L S S Q Q D A A F A F A S L A I V F S S Y I T L V V L F V P K M R R L I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	O75899
Sequence	>7CA3_Chain_S P P S S P P L S I M G L M P L T K E V A K G S I G R G V L P A V E L A I E Q I R N E S L L R P Y F L D L R L Y D T E C D N A K G L K A F Y D A I K Y G P N H L M V F G G V C P S V T S I I A E S L Q G W N L V Q L S F A A T T P V L A D K K K Y P Y F F R T V P S D N A V N P A I L K L L K H Y Q W K R V G T L T Q D V Q R F S E V R N D L T G V L Y G E D I E I S D T E S F S N D P C T S V K K L K G N D V R I I L G Q F D Q N M A A K V F C C A Y E E N M Y G S K Y Q W I I P G W Y E P S W W E C L R K N L L A A M E G Y I G V D F E P L S S K Q I K T I S G K T P Q Q Y E R E Y N N K R S G V G P S K F H G Y A Y D G I W V I A K T L Q R A M E T L H A S S R H Q R I Q D F N Y T D H T L G R I I L N A M N E T N F F G V T G Q V V F R N G E R M G T I K F T Q F Q D S R E V K V G E Y N A V A D T L E I I N D T I R F Q G S E P P K D K T I I L E Q L R K I S L P L Y S I L S A L T I L G M I M A S A F L F F N I K N R N Q K L I K M S S P Y M N N L I I L G G M L S Y A S I F L F G L D G S F V S E K T F E T L C T V R T W I L T V G Y T T A F G A M F A K T W R V H A I F K I K D Q K L L V I V G G M L L I D L C I L I C W Q A V D P L R R T V E K Y S M E P D P A G R D I S I R P L L E H C E N T H M T I W L G I V Y A Y K G L L M L F G C F L A W E T R N V S I P A L N D S K Y I G M S V Y N V G I M C I I G A A V S F L T R D Q P N V Q F C I V A L V I I F C S T I T L C L V F V P K L I T L R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6W2Y	C	Aminoacid	GABAB	GABAB1; GABAB1	Homo sapiens	PubChem 5311042	PubChem 23727970	-	3.2	2020-07-01	10.1038/s41586-020-2469-4
	6UO8	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	GS39783	-	3.63	2020-06-10	10.1038/s41586-020-2408-4
	6UO9	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	-	-	4.8	2020-06-10	10.1038/s41586-020-2408-4
	6UOA	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	6.3	2020-06-10	10.1038/s41586-020-2408-4
	6VJM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	3.97	2020-06-10	10.1038/s41586-020-2408-4
	6W2X	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	PubChem 5311042	PubChem 23727970	-	3.6	2020-07-01	10.1038/s41586-020-2469-4
	6WIV	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	PubChem 52923113; PubChem 52924645	-	3.3	2020-07-01	10.1038/s41586-020-2452-0
	7C7Q	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	Baclofen	PubChem 7023848	-	3	2020-07-01	10.1038/s41422-020-0350-5
	7C7S	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	-	-	2.9	2020-07-01	10.1038/s41422-020-0350-5
	7CA5	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	7.6	2020-11-11	10.1016/j.jmb.2020.09.023
	7CUM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	Phospholipid	-	3.52	2020-11-11	10.1016/j.jmb.2020.09.023
	7EB2	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	Baclofen	rac-BHFF	Gi1/&β;1/&γ;2	3.5	2021-05-05	10.1038/s41586-021-03507-1

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