psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D208	R:R:R168	2.38	No	No	33	4	4
2	R:R:R168	R:R:Y209	6.17	No	Yes	33	4	8
3	R:R:E496	R:R:R168	13.96	No	No	0	4	4
4	R:R:A169	R:R:E210	3.02	No	No	0	3	5
5	R:R:K212	R:R:Y171	4.78	No	No	0	3	5
6	R:R:P237	R:R:Y171	11.13	No	No	0	6	5
7	R:R:G173	R:R:I172	3.53	Yes	No	0	7	8
8	R:R:I172	R:R:I241	2.94	No	Yes	0	8	7
9	R:R:A174	R:R:G173	1.95	No	Yes	0	7	7
10	R:R:G173	R:R:I214	1.76	Yes	No	0	7	3
11	R:R:G173	R:R:K239	1.74	Yes	No	0	7	7
12	R:R:G173	R:R:L242	1.71	Yes	No	0	7	6
13	R:R:A174	R:R:F176	2.77	No	Yes	0	7	7
14	R:R:A174	R:R:M243	1.61	No	Yes	0	7	7
15	R:R:L175	R:R:P244	1.64	No	Yes	0	6	8
16	R:R:F176	R:R:P177	4.33	Yes	No	0	7	7
17	R:R:F176	R:R:Q189	4.68	Yes	No	0	7	4
18	R:R:F176	R:R:V192	2.62	Yes	No	0	7	7
19	R:R:F176	R:R:Y267	6.19	Yes	No	0	7	7
20	R:R:G185	R:R:P177	4.06	No	No	0	7	7
21	R:R:D217	R:R:M178	11.09	No	No	0	8	5
22	R:R:G180	R:R:S179	3.71	No	No	0	3	6
23	R:R:K219	R:R:S179	3.06	No	No	0	5	6
24	R:R:G180	R:R:G181	2.11	No	No	0	3	5
25	R:R:G181	R:R:Y367	4.35	No	No	0	5	7
26	R:R:G184	R:R:W182	2.81	No	Yes	0	5	6
27	R:R:G268	R:R:W182	2.81	Yes	Yes	0	7	6
28	R:R:W182	R:R:W395	14.06	Yes	No	0	6	5
29	R:R:E466	R:R:W182	7.63	No	Yes	0	5	6
30	R:R:P183	R:R:Q186	1.58	No	No	0	4	4
31	R:R:G184	R:R:G185	2.11	No	No	0	5	7
32	R:R:G184	R:R:G463	2.11	No	No	0	5	4
33	R:R:C188	R:R:G185	3.92	No	No	0	5	7
34	R:R:A467	R:R:C188	3.61	No	No	0	7	5
35	R:R:P190	R:R:Q189	3.16	No	No	0	5	4
36	R:R:H215	R:R:Q189	9.89	No	No	0	2	4
37	R:R:P190	R:R:R453	2.88	No	No	0	5	1
38	R:R:A191	R:R:L450	1.58	No	No	0	8	7
39	R:R:A191	R:R:A467	1.79	No	No	0	8	7
40	R:R:A470	R:R:V192	3.39	No	No	0	7	7
41	R:R:E193	R:R:L213	3.98	No	No	0	4	6
42	R:R:K449	R:R:M194	11.52	No	No	0	5	7
43	R:R:M194	R:R:R453	8.69	No	No	0	7	1
44	R:R:A195	R:R:Y471	4	No	Yes	0	9	9
45	R:R:E197	R:R:R453	4.65	No	No	0	5	1
46	R:R:D198	R:R:Y471	4.6	No	Yes	9	7	9
47	R:R:D198	R:R:W475	7.82	No	Yes	9	7	8
48	R:R:N200	R:R:V199	4.43	No	No	0	9	7
49	R:R:I205	R:R:V199	7.68	Yes	No	0	6	7
50	R:R:V199	R:R:W475	4.9	No	Yes	0	7	8
51	R:R:E210	R:R:N200	9.2	No	No	0	5	9
52	R:R:R202	R:R:S201	2.64	Yes	No	0	5	4
53	R:R:D204	R:R:R202	16.68	No	Yes	9	4	5
54	R:R:I205	R:R:R202	8.77	Yes	Yes	9	6	5
55	R:R:R202	R:R:W475	2	Yes	Yes	9	5	8
56	R:R:D204	R:R:I205	7	No	Yes	9	4	6
57	R:R:A478	R:R:I205	1.62	No	Yes	0	9	6
58	R:R:L206	R:R:P207	4.93	No	No	0	9	3
59	R:R:L206	R:R:Y209	11.72	No	Yes	0	9	8
60	R:R:D208	R:R:P207	11.27	No	No	0	4	3
61	R:R:D208	R:R:Y209	3.45	No	Yes	33	4	8
62	R:R:L495	R:R:Y209	7.03	No	Yes	0	7	8
63	R:R:H215	R:R:L213	3.86	No	No	0	2	6
64	R:R:H216	R:R:I214	3.98	No	No	0	6	3
65	R:R:H216	R:R:Y228	15.24	No	No	0	6	5
66	R:R:H216	R:R:L232	6.43	No	No	0	6	6
67	R:R:D217	R:R:K219	6.91	No	No	0	8	5
68	R:R:K219	R:R:Q224	8.14	No	No	0	5	5
69	R:R:C220	R:R:C246	7.28	No	No	10	8	7
70	R:R:C220	R:R:S248	1.72	No	Yes	10	8	5
71	R:R:D221	R:R:P222	4.83	Yes	No	10	6	6
72	R:R:D221	R:R:G223	1.68	Yes	Yes	10	6	7
73	R:R:D221	R:R:Q224	7.83	Yes	No	0	6	5
74	R:R:D221	S:S:E144	7.8	Yes	No	10	6	7
75	R:R:P222	R:R:S248	1.78	No	Yes	10	6	5
76	R:R:P222	S:S:E144	14.15	No	No	10	6	7
77	R:R:G223	R:R:T226	3.64	Yes	No	10	7	7
78	R:R:G223	S:S:E144	6.55	Yes	No	10	7	7
79	R:R:G223	S:S:S145	3.71	Yes	No	10	7	7
80	R:R:T226	S:S:Y118	3.75	No	Yes	0	7	7
81	R:R:T226	S:S:S145	9.59	No	No	10	7	7
82	R:R:E231	R:R:K227	4.05	No	No	0	6	7
83	R:R:K227	S:S:W149	8.12	No	No	0	7	7
84	R:R:L229	S:S:Y118	2.34	No	Yes	0	7	7
85	R:R:Y230	R:R:Y234	5.96	Yes	Yes	12	7	5
86	R:R:Y230	S:S:Y118	6.95	Yes	Yes	0	7	7
87	R:R:Y230	S:S:I121	3.63	Yes	No	0	7	6
88	R:R:Y230	S:S:K122	7.17	Yes	Yes	12	7	4
89	R:R:Y230	S:S:W149	3.86	Yes	No	0	7	7
90	R:R:K239	R:R:L232	8.46	No	No	0	7	6
91	R:R:L233	R:R:Y234	2.34	No	Yes	12	7	5
92	R:R:L233	R:R:W260	5.69	No	Yes	12	7	7
93	R:R:L233	R:R:Y500	5.86	No	Yes	12	7	8
94	R:R:W260	R:R:Y234	7.72	Yes	Yes	12	7	5
95	R:R:Y234	S:S:K122	3.58	Yes	Yes	12	5	4
96	R:R:N235	S:S:K122	5.6	No	Yes	0	3	4
97	R:R:D236	R:R:P237	8.05	No	No	0	3	6
98	R:R:D236	R:R:K239	5.53	No	No	0	3	7
99	R:R:F498	R:R:I238	2.51	No	No	0	8	5
100	R:R:I240	R:R:I241	5.89	No	Yes	0	5	7
101	R:R:F498	R:R:I240	8.79	No	No	0	8	5
102	R:R:I241	R:R:I263	4.42	Yes	No	0	7	6
103	R:R:I241	R:R:L477	2.85	Yes	No	0	7	5
104	R:R:L242	R:R:P244	1.64	No	Yes	0	6	8
105	R:R:M243	R:R:P244	1.68	Yes	Yes	0	7	8
106	R:R:L265	R:R:M243	5.65	No	Yes	0	6	7
107	R:R:M243	R:R:Y267	4.79	Yes	No	0	7	7
108	R:R:G245	R:R:P244	2.03	No	Yes	0	6	8
109	R:R:P244	R:R:V264	3.53	Yes	No	0	8	9
110	R:R:P244	R:R:S266	1.78	Yes	Yes	0	8	8
111	R:R:G245	R:R:Y267	4.35	No	No	0	6	7
112	R:R:C246	R:R:S248	1.72	No	Yes	10	7	5
113	R:R:C246	R:R:V249	3.42	No	No	10	7	8
114	R:R:S247	R:R:S269	6.52	No	Yes	6	9	8
115	R:R:S247	R:R:S271	3.26	No	Yes	6	9	9
116	R:R:S247	R:R:V318	4.85	No	Yes	6	9	5
117	R:R:S248	R:R:V249	3.23	Yes	No	10	5	8
118	R:R:S250	R:R:T251	1.6	No	Yes	0	8	7
119	R:R:S250	R:R:S269	4.89	No	Yes	0	8	8
120	R:R:F283	R:R:S250	3.96	Yes	No	0	8	8
121	R:R:S271	R:R:T251	3.2	Yes	Yes	6	9	7
122	R:R:L274	R:R:T251	2.95	Yes	Yes	6	8	7
123	R:R:E317	R:R:T251	2.82	No	Yes	0	6	7
124	R:R:A254	R:R:F280	4.16	No	Yes	0	8	8
125	R:R:E255	R:R:R279	4.65	No	Yes	6	8	6
126	R:R:E255	R:R:F280	8.16	No	Yes	6	8	8
127	R:R:E255	S:S:N110	5.26	No	Yes	0	8	5
128	R:R:A257	R:R:L262	1.58	No	No	0	7	7
129	R:R:A257	R:R:T282	1.68	No	No	0	7	8
130	R:R:M259	R:R:R258	2.48	Yes	No	0	5	5
131	R:R:R258	S:S:D109	5.96	No	No	0	5	5
132	R:R:M259	R:R:W260	2.33	Yes	Yes	12	5	7
133	R:R:M259	S:S:A111	1.61	Yes	No	0	5	7
134	R:R:M259	S:S:K115	7.2	Yes	No	12	5	6
135	R:R:L262	R:R:W260	2.28	No	Yes	12	7	7
136	R:R:W260	R:R:Y500	12.54	Yes	Yes	12	7	8
137	R:R:W260	S:S:K115	2.32	Yes	No	12	7	6
138	R:R:N261	R:R:Q503	11.88	No	Yes	15	8	3
139	R:R:N261	R:R:T506	5.85	No	No	15	8	5
140	R:R:L262	R:R:Y500	2.34	No	Yes	12	7	8
141	R:R:I263	R:R:T282	4.56	No	No	0	6	8
142	R:R:F284	R:R:I263	3.77	Yes	No	0	6	6
143	R:R:F283	R:R:V264	5.24	Yes	No	0	8	9
144	R:R:F284	R:R:L265	2.44	Yes	No	0	6	6
145	R:R:A473	R:R:L265	1.58	No	No	0	8	6
146	R:R:G268	R:R:S266	1.86	Yes	Yes	6	7	8
147	R:R:S266	R:R:S269	3.26	Yes	Yes	6	8	8
148	R:R:F283	R:R:S266	2.64	Yes	Yes	6	8	8
149	R:R:G268	R:R:S269	1.86	Yes	Yes	6	7	8
150	R:R:G268	R:R:H287	4.77	Yes	No	0	7	7
151	R:R:A290	R:R:S270	3.42	No	No	0	8	7
152	R:R:P272	R:R:S271	1.78	No	Yes	0	7	9
153	R:R:L274	R:R:S271	3	Yes	Yes	6	8	9
154	R:R:S271	R:R:V318	8.08	Yes	Yes	6	9	5
155	R:R:P272	R:R:S321	1.78	No	No	0	7	6
156	R:R:P272	R:R:T322	5.25	No	No	0	7	7
157	R:R:A273	R:R:L274	1.58	No	Yes	0	6	8
158	R:R:A273	R:R:S321	1.71	No	No	0	6	6
159	R:R:F280	R:R:L274	7.31	Yes	Yes	6	8	8
160	R:R:F283	R:R:L274	8.53	Yes	Yes	6	8	8
161	R:R:L274	R:R:R285	3.64	Yes	Yes	6	8	9
162	R:R:R285	R:R:S275	2.64	Yes	No	0	9	8
163	R:R:A529	R:R:S275	1.71	No	No	0	4	8
164	R:R:N276	R:R:Q278	3.96	No	No	0	7	3
165	R:R:N276	R:R:R279	4.82	No	Yes	0	7	6
166	R:R:F284	R:R:R277	2.14	Yes	No	24	6	7
167	R:R:R277	R:R:Y510	2.06	No	No	24	7	5
168	R:R:F280	R:R:R279	22.45	Yes	Yes	6	8	6
169	R:R:E317	R:R:R279	4.65	No	Yes	0	6	6
170	R:R:P281	R:R:T282	6.99	No	No	0	7	8
171	R:R:F283	R:R:R285	3.21	Yes	Yes	6	8	9
172	R:R:F284	R:R:Y510	5.16	Yes	No	24	6	5
173	R:R:F284	R:R:M513	11.2	Yes	No	24	6	6
174	R:R:F284	R:R:F527	6.43	Yes	No	24	6	9
175	R:R:R285	R:R:S289	6.59	Yes	No	0	9	8
176	R:R:L469	R:R:T286	8.84	No	No	0	6	7
177	R:R:R533	R:R:T286	5.17	Yes	No	0	9	7
178	R:R:H287	R:R:P288	9.15	No	No	0	7	6
179	R:R:I427	R:R:P288	1.69	No	No	34	5	6
180	R:R:M429	R:R:P288	1.68	No	No	34	4	6
181	R:R:S289	R:R:T291	1.6	No	No	0	8	6
182	R:R:G531	R:R:S289	1.86	No	No	0	8	8
183	R:R:A290	R:R:H293	4.39	No	Yes	0	8	5
184	R:R:D325	R:R:T291	5.78	No	No	0	6	6
185	R:R:H293	R:R:R297	4.51	Yes	Yes	0	5	7
186	R:R:H293	R:R:T425	4.11	Yes	No	0	5	6
187	R:R:H293	R:R:I427	6.63	Yes	No	0	5	5
188	R:R:N294	R:R:P295	3.26	No	No	0	9	3
189	R:R:N294	R:R:R297	4.82	No	Yes	0	9	7
190	R:R:L326	R:R:N294	12.36	No	No	0	8	9
191	R:R:P295	R:R:R329	4.32	No	No	0	3	4
192	R:R:T296	R:R:T537	4.71	No	No	25	8	6
193	R:R:T296	R:R:Y553	2.5	No	Yes	25	8	6
194	R:R:F301	R:R:R297	3.21	No	Yes	13	6	7
195	R:R:F391	R:R:R297	3.21	Yes	Yes	13	7	7
196	R:R:V298	R:R:V330	1.6	No	No	0	6	7
197	R:R:K299	R:R:Y553	9.55	No	Yes	25	6	6
198	R:R:D558	R:R:K299	8.3	No	No	25	4	6
199	R:R:L300	R:R:W304	3.42	No	Yes	0	6	7
200	R:R:F301	R:R:W306	3.01	No	Yes	13	6	9
201	R:R:F301	R:R:F391	10.72	No	Yes	13	6	7
202	R:R:K303	R:R:W304	12.76	No	Yes	0	4	7
203	R:R:K303	R:R:W562	10.44	No	Yes	0	4	5
204	R:R:W304	R:R:W306	5.62	Yes	Yes	13	7	9
205	R:R:W304	R:R:W568	10.31	Yes	Yes	13	7	9
206	R:R:P573	R:R:W304	13.51	Yes	Yes	13	5	7
207	R:R:I361	R:R:W306	9.4	No	Yes	13	9	9
208	R:R:V389	R:R:W306	2.45	No	Yes	13	8	9
209	R:R:F391	R:R:W306	2	Yes	Yes	13	7	9
210	R:R:A575	R:R:W306	2.59	No	Yes	0	4	9
211	R:R:D576	R:R:W306	3.35	No	Yes	0	9	9
212	R:R:I335	R:R:K307	2.91	No	No	0	7	5
213	R:R:K308	R:R:Q577	12.2	No	No	0	7	5
214	R:R:I309	R:R:I337	4.42	No	No	0	8	6
215	R:R:I309	R:R:I361	5.89	No	No	0	8	9
216	R:R:A310	R:R:F339	2.77	No	Yes	0	8	6
217	R:R:A310	R:R:L354	1.58	No	No	0	8	8
218	R:R:L323	R:R:T311	5.9	No	No	0	6	7
219	R:R:R340	R:R:T311	3.88	Yes	No	0	6	7
220	R:R:T311	R:R:V363	1.59	No	No	0	7	7
221	R:R:I312	R:R:Q341	4.12	No	Yes	0	6	7
222	R:R:Q313	R:R:T320	5.67	Yes	No	0	7	7
223	R:R:L323	R:R:Q313	5.32	No	Yes	0	6	7
224	R:R:Q313	R:R:S342	4.33	Yes	No	17	7	7
225	R:R:Q313	S:S:D204	3.92	Yes	No	17	7	6
226	R:R:Q314	R:R:T316	9.92	No	No	0	8	5
227	R:R:F343	R:R:Q314	2.34	No	No	0	7	8
228	R:R:T315	R:R:T320	1.57	No	No	0	6	7
229	R:R:T315	S:S:Q206	12.76	No	No	0	6	6
230	R:R:T316	R:R:V318	4.76	No	Yes	0	5	5
231	R:R:F319	R:R:V318	15.73	No	Yes	0	7	5
232	R:R:F319	R:R:Y367	5.16	No	No	0	7	7
233	R:R:S321	R:R:T320	1.6	No	No	0	6	7
234	R:R:D325	R:R:E328	5.2	No	No	35	6	4
235	R:R:D325	R:R:R329	3.57	No	No	35	6	4
236	R:R:E327	R:R:I337	4.1	No	No	17	5	6
237	R:R:E327	R:R:R340	3.49	No	Yes	17	5	6
238	R:R:E328	R:R:R329	11.63	No	No	35	4	4
239	R:R:I335	R:R:V330	7.68	No	No	0	7	7
240	R:R:A333	R:R:E332	6.03	No	No	0	5	3
241	R:R:I337	R:R:R340	3.76	No	Yes	17	6	6
242	R:R:F339	R:R:Q341	10.54	Yes	Yes	18	6	7
243	R:R:F339	R:R:N353	4.83	Yes	No	18	6	6
244	R:R:F339	R:R:Q357	7.03	Yes	No	0	6	6
245	R:R:R340	S:S:D204	9.53	Yes	No	17	6	6
246	R:R:R340	S:S:S233	7.91	Yes	No	0	6	4
247	R:R:P350	R:R:Q341	7.9	Yes	Yes	18	7	7
248	R:R:N353	R:R:Q341	3.96	No	Yes	18	6	7
249	R:R:S342	S:S:D204	5.89	No	No	17	7	6
250	R:R:S342	S:S:S209	6.52	No	No	0	7	6
251	R:R:F343	R:R:P347	5.78	No	No	0	7	6
252	R:R:F344	S:S:V162	6.55	Yes	No	36	4	6
253	R:R:F344	S:S:K168	3.72	Yes	No	0	4	5
254	R:R:F344	S:S:Q206	2.34	Yes	No	36	4	6
255	R:R:F344	S:S:E210	3.5	Yes	No	0	4	6
256	R:R:D346	R:R:P347	3.22	No	No	0	6	6
257	R:R:P347	R:R:V374	1.77	No	No	0	6	7
258	R:R:A348	R:R:V349	1.7	No	Yes	0	3	3
259	R:R:A348	R:R:E377	4.53	No	No	0	3	7
260	R:R:P350	R:R:V349	3.53	Yes	Yes	18	7	3
261	R:R:V349	S:S:N213	5.91	Yes	No	18	3	6
262	R:R:V349	S:S:T216	3.17	Yes	No	0	3	5
263	R:R:P350	R:R:V351	1.77	Yes	No	0	7	8
264	R:R:P350	S:S:N213	8.15	Yes	No	18	7	6
265	R:R:V351	R:R:V378	1.6	No	Yes	0	8	8
266	R:R:E381	R:R:K352	9.45	No	No	0	5	4
267	R:R:N353	S:S:T229	11.7	No	No	0	6	6
268	R:R:K355	R:R:L383	4.23	No	Yes	19	8	7
269	R:R:K355	R:R:Y388	2.39	No	No	19	8	8
270	R:R:K387	R:R:R360	13.61	No	No	0	6	9
271	R:R:R360	R:R:T578	5.17	No	Yes	37	9	6
272	R:R:D751	R:R:R360	8.34	No	No	37	8	9
273	R:R:I361	R:R:V389	3.07	No	No	13	9	8
274	R:R:I362	R:R:W390	18.79	No	No	0	9	9
275	R:R:G364	R:R:V363	3.68	No	No	0	6	7
276	R:R:G364	R:R:L365	1.71	No	No	0	6	6
277	R:R:F366	R:R:G364	3.01	No	No	0	8	6
278	R:R:I393	R:R:L365	2.85	Yes	No	0	5	6
279	R:R:A371	R:R:F366	4.16	No	No	0	8	8
280	R:R:F366	R:R:Y396	2.06	No	Yes	0	8	5
281	R:R:E368	R:R:T369	5.64	No	No	5	7	3
282	R:R:E368	R:R:R372	16.28	No	Yes	5	7	7
283	R:R:E368	R:R:Y396	3.37	No	Yes	0	7	5
284	R:R:R372	R:R:T369	3.88	Yes	No	5	7	3
285	R:R:A371	R:R:W400	3.89	No	Yes	0	8	8
286	R:R:R372	R:R:W400	2	Yes	Yes	0	7	8
287	R:R:D405	R:R:R372	5.96	Yes	Yes	5	3	7
288	R:R:V374	R:R:V378	1.6	No	Yes	0	7	8
289	R:R:F375	R:R:V378	3.93	Yes	Yes	19	8	8
290	R:R:F375	R:R:W390	18.04	Yes	No	19	8	9
291	R:R:F375	R:R:L392	2.44	Yes	No	0	8	6
292	R:R:F375	R:R:W400	2	Yes	Yes	0	8	8
293	R:R:F375	R:R:V419	2.62	Yes	No	0	8	5
294	R:R:C376	R:R:I408	9.82	No	Yes	5	9	3
295	R:R:C376	R:R:C410	7.28	No	No	5	9	9
296	R:R:V378	R:R:W390	3.68	Yes	No	19	8	9
297	R:R:R382	R:R:Y379	14.4	No	Yes	5	5	7
298	R:R:F384	R:R:Y379	7.22	Yes	Yes	5	5	7
299	R:R:E414	R:R:Y379	22.45	Yes	Yes	5	7	7
300	R:R:E417	R:R:Y379	3.37	No	Yes	5	4	7
301	R:R:F384	R:R:R382	7.48	Yes	No	5	5	5
302	R:R:L383	R:R:Y388	9.38	Yes	No	19	7	8
303	R:R:F384	R:R:G385	3.01	Yes	No	0	5	9
304	R:R:A418	R:R:F384	6.93	No	Yes	0	9	5
305	R:R:I750	R:R:K386	5.82	No	No	0	4	5
306	R:R:K387	R:R:Y388	8.36	No	No	0	6	8
307	R:R:F391	R:R:V389	2.62	Yes	No	13	7	8
308	R:R:H422	R:R:L392	7.71	Yes	No	0	6	6
309	R:R:G394	R:R:I393	1.76	No	Yes	0	8	5
310	R:R:I393	R:R:W395	4.7	Yes	No	0	5	5
311	R:R:I393	R:R:Y396	6.04	Yes	Yes	0	5	5
312	R:R:G394	R:R:T424	3.64	No	No	0	8	6
313	R:R:E426	R:R:G394	4.91	No	No	0	6	8
314	R:R:W400	R:R:Y396	1.93	Yes	Yes	0	8	5
315	R:R:D398	R:R:Y547	2.3	No	Yes	0	4	5
316	R:R:K402	R:R:N399	4.2	No	No	0	2	4
317	R:R:I403	R:R:N399	7.08	No	No	0	1	4
318	R:R:F401	R:R:W400	18.04	No	Yes	0	7	8
319	R:R:W400	R:R:Y547	3.86	Yes	Yes	0	8	5
320	R:R:F401	R:R:K402	9.93	No	No	0	7	2
321	R:R:F401	R:R:M415	2.49	No	No	0	7	6
322	R:R:P406	R:R:Y404	9.74	No	No	0	3	1
323	R:R:D405	R:R:P406	4.83	Yes	No	5	3	3
324	R:R:D405	R:R:S407	4.42	Yes	No	5	3	1
325	R:R:D405	R:R:I408	18.19	Yes	Yes	5	3	3
326	R:R:P406	R:R:S407	3.56	No	No	5	3	1
327	R:R:C410	R:R:I408	3.27	No	Yes	5	9	3
328	R:R:C410	R:R:E414	3.04	No	Yes	5	9	7
329	R:R:T411	R:R:V412	1.59	No	No	0	6	1
330	R:R:E414	R:R:T411	8.47	Yes	No	0	7	6
331	R:R:T416	R:R:V412	3.17	No	No	0	2	1
332	R:R:D413	R:R:E417	3.9	No	No	0	5	4
333	R:R:E414	R:R:E417	2.54	Yes	No	5	7	4
334	R:R:H422	R:R:V419	5.54	Yes	No	0	6	5
335	R:R:E420	R:R:L542	5.3	No	No	0	6	4
336	R:R:E420	R:R:G544	4.91	No	No	0	6	4
337	R:R:H422	R:R:L542	10.29	Yes	No	26	6	4
338	R:R:H422	R:R:Y547	3.27	Yes	Yes	26	6	5
339	R:R:E540	R:R:T424	8.47	No	No	26	6	6
340	R:R:T424	R:R:Y547	2.5	No	Yes	26	6	5
341	R:R:E426	R:R:L538	6.63	No	No	0	6	4
342	R:R:I427	R:R:M429	4.37	No	No	34	5	4
343	R:R:L469	R:R:M429	2.83	No	No	0	6	4
344	R:R:L430	R:R:P432	3.28	No	No	0	3	4
345	R:R:N431	R:R:P432	6.52	No	No	0	6	4
346	R:R:A433	R:R:N431	3.13	No	No	0	3	6
347	R:R:G523	R:R:N431	1.7	No	No	0	9	6
348	R:R:A433	R:R:T435	1.68	No	No	0	3	3
349	R:R:N440	R:R:R436	20.49	No	No	0	7	1
350	R:R:S437	R:R:S439	4.89	No	Yes	9	7	8
351	R:R:M441	R:R:S437	4.6	Yes	No	9	5	7
352	R:R:I438	R:R:W475	2.35	No	Yes	0	5	8
353	R:R:M441	R:R:S439	3.07	Yes	Yes	9	5	8
354	R:R:S439	R:R:Y471	6.36	Yes	Yes	9	8	9
355	R:R:S439	R:R:W475	4.94	Yes	Yes	9	8	8
356	R:R:E445	R:R:M441	4.06	No	Yes	0	5	5
357	R:R:F446	R:R:M441	2.49	Yes	Yes	9	7	5
358	R:R:M441	R:R:Y471	2.39	Yes	Yes	9	5	9
359	R:R:S443	R:R:T442	3.2	No	No	38	4	8
360	R:R:Q444	R:R:T442	5.67	No	No	38	4	8
361	R:R:Q444	R:R:S443	7.22	No	No	38	4	4
362	R:R:F446	R:R:L450	7.31	Yes	No	0	7	7
363	R:R:F446	R:R:P468	4.33	Yes	Yes	0	7	5
364	R:R:F446	R:R:Y471	6.19	Yes	Yes	9	7	9
365	R:R:T451	R:R:V447	1.59	No	No	0	2	2
366	R:R:F464	R:R:V447	2.62	No	No	0	7	2
367	R:R:E448	R:R:T451	4.23	No	No	0	1	2
368	R:R:E448	R:R:K452	2.7	No	No	0	1	2
369	R:R:F464	R:R:L450	4.87	No	No	0	7	7
370	R:R:G462	R:R:G463	2.11	No	No	0	3	4
371	R:R:E466	R:R:G463	4.91	No	No	0	5	4
372	R:R:F464	R:R:Q465	2.34	No	No	0	7	4
373	R:R:E466	R:R:Q465	5.1	No	No	0	5	4
374	R:R:A467	R:R:P468	1.87	No	Yes	0	7	5
375	R:R:L469	R:R:P468	1.64	No	Yes	0	6	5
376	R:R:D472	R:R:P468	1.61	Yes	Yes	0	9	5
377	R:R:A470	R:R:I474	1.62	No	No	0	7	6
378	R:R:W475	R:R:Y471	17.36	Yes	Yes	9	8	9
379	R:R:V521	R:R:Y471	3.79	No	Yes	0	8	9
380	R:R:D472	R:R:G520	1.68	Yes	No	0	9	9
381	R:R:D472	R:R:V521	7.3	Yes	No	0	9	8
382	R:R:D472	R:R:S522	8.83	Yes	Yes	0	9	9
383	R:R:A473	R:R:I474	3.25	No	No	0	8	6
384	R:R:A476	R:R:F518	2.77	No	No	0	7	9
385	R:R:L477	R:R:L481	4.15	No	No	0	5	8
386	R:R:A480	R:R:I509	1.62	No	No	0	8	6
387	R:R:K483	R:R:S515	3.06	No	No	0	4	5
388	R:R:S485	R:R:T484	3.2	No	No	0	4	8
389	R:R:L495	R:R:R494	2.43	No	No	0	7	4
390	R:R:Q508	R:R:R494	7.01	No	No	0	5	4
391	R:R:F498	R:R:I505	11.3	No	No	0	8	6
392	R:R:N499	R:R:Y500	3.49	No	Yes	0	5	8
393	R:R:N499	R:R:N501	14.98	No	No	0	5	4
394	R:R:N502	R:R:T504	11.7	No	No	15	7	4
395	R:R:I505	R:R:N502	7.08	No	No	15	6	7
396	R:R:Q503	R:R:T506	2.83	Yes	No	15	3	5
397	R:R:D507	R:R:Q503	6.53	No	Yes	15	3	3
398	R:R:I505	R:R:T504	3.04	No	No	15	6	4
399	R:R:D507	R:R:T506	4.34	No	No	15	3	5
400	R:R:Q508	R:R:R511	4.67	No	No	0	5	4
401	R:R:A512	R:R:I509	1.62	No	No	0	6	6
402	R:R:M513	R:R:S516	7.67	No	No	0	6	6
403	R:R:F527	R:R:M513	4.98	No	No	24	9	6
404	R:R:S517	R:R:V526	4.85	No	No	0	4	5
405	R:R:F518	R:R:G520	3.01	No	No	16	9	9
406	R:R:F518	R:R:V525	7.87	No	No	16	9	8
407	R:R:E519	R:R:G523	1.64	No	No	0	2	9
408	R:R:E519	R:R:H524	22.16	No	No	0	2	4
409	R:R:G520	R:R:V525	1.84	No	No	16	9	8
410	R:R:G523	R:R:S522	3.71	No	Yes	0	9	9
411	R:R:R533	R:R:S522	6.59	Yes	Yes	16	9	9
412	R:R:M534	R:R:S522	3.07	No	Yes	16	5	9
413	R:R:H524	R:R:V526	6.92	No	No	0	4	5
414	R:R:R533	R:R:V525	2.62	Yes	No	16	9	8
415	R:R:D528	R:R:S530	7.36	No	No	0	6	5
416	R:R:D528	R:R:G531	1.68	No	No	0	6	8
417	R:R:S530	R:R:S532	4.89	No	No	0	5	7
418	R:R:M534	R:R:R533	12.41	No	Yes	16	5	9
419	R:R:A535	R:R:D554	4.63	No	Yes	39	6	5
420	R:R:A535	R:R:T556	1.68	No	No	39	6	1
421	R:R:W536	R:R:Y552	4.82	No	No	0	3	4
422	R:R:D554	R:R:W536	10.05	Yes	No	0	5	3
423	R:R:T537	R:R:Y553	4.99	No	Yes	25	6	6
424	R:R:E540	R:R:L538	2.65	No	No	0	6	4
425	R:R:K549	R:R:L538	2.82	No	No	0	3	4
426	R:R:I539	R:R:I550	2.94	No	Yes	40	7	7
427	R:R:G551	R:R:I539	1.76	No	No	40	7	7
428	R:R:E540	R:R:Y547	17.96	No	Yes	26	6	5
429	R:R:Q541	R:R:Q543	11.52	No	No	0	9	8
430	R:R:L542	R:R:Y547	7.03	No	Yes	26	4	5
431	R:R:K548	R:R:Q543	12.2	No	No	0	4	8
432	R:R:K567	R:R:Q543	16.27	No	No	0	1	8
433	R:R:G544	R:R:G545	2.11	No	No	0	4	4
434	R:R:G545	R:R:S546	1.86	No	No	0	4	1
435	R:R:K549	R:R:Y552	4.78	No	No	0	3	4
436	R:R:G551	R:R:I550	3.53	No	Yes	40	7	7
437	R:R:I550	R:R:W562	10.57	Yes	Yes	0	7	5
438	R:R:S555	R:R:Y553	5.09	No	Yes	0	4	6
439	R:R:D558	R:R:Y553	4.6	No	Yes	25	4	6
440	R:R:L560	R:R:Y553	5.86	No	Yes	0	7	6
441	R:R:D554	R:R:T556	11.56	Yes	No	39	5	1
442	R:R:D554	R:R:D559	7.98	Yes	No	0	5	4
443	R:R:K557	R:R:T556	12.01	No	No	0	3	1
444	R:R:D559	R:R:K557	8.3	No	No	0	4	3
445	R:R:L560	R:R:W562	6.83	No	Yes	0	7	5
446	R:R:K564	R:R:W562	18.57	No	Yes	0	4	5
447	R:R:S563	R:R:T565	6.4	No	No	0	1	3
448	R:R:D566	R:R:W568	2.23	No	Yes	0	5	9
449	R:R:G571	R:R:W568	2.81	No	Yes	0	4	9
450	R:R:P573	R:R:W568	13.51	Yes	Yes	13	5	9
451	R:R:G570	R:R:G571	2.11	No	No	0	6	4
452	R:R:G571	R:R:S572	3.71	No	No	0	4	3
453	R:R:P573	R:R:S572	3.56	Yes	No	0	5	3
454	R:R:P573	R:R:P574	1.95	Yes	No	0	5	9
455	R:R:A575	R:R:L579	1.58	No	No	0	4	3
456	R:R:D576	R:R:Q577	3.92	No	No	0	9	5
457	R:R:D751	R:R:T578	10.12	No	Yes	37	8	6
458	R:R:T578	R:R:V752	3.17	Yes	No	0	6	5
459	R:R:S753	R:R:T578	1.6	No	Yes	0	2	6
460	R:R:S753	R:R:V580	1.62	No	No	0	2	4
461	R:R:L755	R:R:V580	7.45	Yes	No	0	4	4
462	R:R:I581	R:R:V752	6.14	No	No	0	2	5
463	R:R:I581	R:R:I754	2.94	No	No	0	2	5
464	R:R:K582	R:R:L755	4.23	No	Yes	0	1	4
465	R:R:K582	R:R:Q757	5.42	No	Yes	0	1	5
466	R:R:F586	R:R:T583	2.59	No	No	0	4	5
467	R:R:F584	R:R:F586	2.14	No	No	0	4	4
468	R:R:F584	R:R:Q757	11.71	No	Yes	0	4	5
469	R:R:L758	R:R:R585	4.86	Yes	No	0	5	5
470	R:R:D831	R:R:R585	14.29	No	No	0	7	5
471	R:R:F586	R:R:Y652	2.06	No	No	0	4	4
472	R:R:D650	R:R:L587	8.14	Yes	No	29	9	7
473	R:R:G651	R:R:L587	1.71	No	No	29	5	7
474	R:R:L587	R:R:Q830	9.32	No	No	0	7	5
475	R:R:F592	R:R:Q589	14.05	Yes	No	0	5	2
476	R:R:Q589	R:R:Y652	7.89	No	No	0	2	4
477	R:R:K590	R:R:Y652	2.39	No	No	0	3	4
478	R:R:F592	R:R:S596	7.93	Yes	No	20	5	3
479	R:R:F592	R:R:V644	2.62	Yes	Yes	20	5	8
480	R:R:F592	R:R:G648	4.52	Yes	No	20	5	8
481	R:R:F592	R:R:L649	7.31	Yes	No	20	5	5
482	R:R:S596	R:R:V595	1.62	No	Yes	20	3	6
483	R:R:V595	R:R:V644	1.6	Yes	Yes	20	6	8
484	R:R:F834	R:R:V595	2.62	No	Yes	0	7	6
485	R:R:S596	R:R:V644	1.62	No	Yes	20	3	8
486	R:R:S600	R:R:V597	1.62	No	No	0	3	3
487	R:R:L598	R:R:V842	4.47	No	No	0	4	5
488	R:R:S599	R:R:S600	1.63	No	No	0	7	3
489	R:R:L641	R:R:S599	3	No	No	0	8	7
490	R:R:L601	R:R:S600	3	No	No	0	3	3
491	R:R:G602	R:R:L601	1.71	No	No	0	9	3
492	R:R:G602	R:R:L641	1.71	No	No	0	9	8
493	R:R:G602	R:R:S845	1.86	No	No	0	9	8
494	R:R:I603	R:R:S638	4.64	No	No	0	8	6
495	R:R:I603	R:R:L641	2.85	No	No	0	8	8
496	R:R:V604	R:R:V608	1.6	No	No	0	3	1
497	R:R:A606	R:R:S638	1.71	No	No	0	7	6
498	R:R:C609	R:R:F853	9.78	No	Yes	0	8	9
499	R:R:L610	R:R:N631	6.87	No	No	0	8	8
500	R:R:F612	R:R:N613	8.46	No	Yes	0	8	9
501	R:R:N613	R:R:P627	1.63	Yes	No	21	9	9
502	R:R:N613	R:R:N631	2.72	Yes	No	21	9	8
503	R:R:F853	R:R:N613	15.71	Yes	Yes	21	9	9
504	R:R:N616	R:R:Y615	12.79	No	No	0	5	2
505	R:R:H618	R:R:Q623	3.71	No	No	0	6	8
506	R:R:I622	R:R:V619	9.22	No	No	0	9	5
507	R:R:N624	R:R:R620	2.41	No	No	0	8	8
508	R:R:R859	R:R:Y621	15.43	No	No	0	5	4
509	R:R:K798	R:R:N624	6.99	No	No	0	7	8
510	R:R:I799	R:R:S625	3.1	No	Yes	22	8	9
511	R:R:D801	R:R:S625	5.89	No	Yes	22	9	9
512	R:R:K856	R:R:S625	3.06	No	Yes	0	9	9
513	R:R:P627	R:R:Q626	1.58	No	No	0	9	9
514	R:R:L629	R:R:Q626	6.65	No	No	0	6	9
515	R:R:P707	R:R:Q626	1.58	No	No	0	8	9
516	R:R:N631	R:R:P627	1.63	No	No	21	8	9
517	R:R:N628	R:R:Y711	3.49	No	No	0	5	5
518	R:R:K684	R:R:L629	4.23	No	No	0	9	6
519	R:R:L629	R:R:Y711	3.52	No	No	0	6	5
520	R:R:K684	R:R:N630	8.39	No	No	0	9	9
521	R:R:L852	R:R:N630	5.49	No	No	21	7	9
522	R:R:F853	R:R:N630	4.83	Yes	No	21	9	9
523	R:R:G677	R:R:T633	5.46	No	No	42	7	7
524	R:R:S680	R:R:T633	7.99	No	No	42	7	7
525	R:R:A634	R:R:L849	4.73	No	Yes	0	7	8
526	R:R:G636	R:R:V635	3.68	No	No	0	9	4
527	R:R:G636	R:R:L639	3.42	No	Yes	43	9	6
528	R:R:G636	R:R:G673	2.11	No	No	43	9	9
529	R:R:C637	R:R:S844	1.72	No	Yes	41	5	7
530	R:R:C637	R:R:S845	1.72	No	No	41	5	8
531	R:R:C637	R:R:L849	1.59	No	Yes	0	5	8
532	R:R:G673	R:R:L639	5.13	No	Yes	43	9	6
533	R:R:A640	R:R:G673	1.95	No	No	0	7	9
534	R:R:A640	R:R:I841	1.62	No	Yes	0	7	7
535	R:R:A642	R:R:L669	1.58	No	Yes	0	3	5
536	R:R:A643	R:R:L669	1.58	No	Yes	0	8	5
537	R:R:S838	R:R:V644	4.85	No	Yes	0	7	8
538	R:R:F645	R:R:P646	2.89	No	No	0	5	6
539	R:R:A665	R:R:P646	1.87	No	No	0	5	6
540	R:R:L669	R:R:P646	1.64	Yes	No	0	5	6
541	R:R:L647	R:R:R666	14.58	No	No	0	5	8
542	R:R:G648	R:R:L649	1.71	No	No	20	8	5
543	R:R:F834	R:R:G648	4.52	No	No	0	7	8
544	R:R:I654	R:R:L649	7.14	No	No	0	5	5
545	R:R:D650	R:R:G651	5.03	Yes	No	29	9	5
546	R:R:D650	R:R:F659	4.78	Yes	Yes	0	9	4
547	R:R:D650	R:R:E759	12.99	Yes	No	29	9	7
548	R:R:E759	R:R:G651	1.64	No	No	29	7	5
549	R:R:H653	R:R:R656	4.51	No	No	0	4	1
550	R:R:G655	R:R:I654	5.29	No	No	0	5	5
551	R:R:N657	R:R:Q658	5.28	No	No	0	1	3
552	R:R:F661	R:R:Q658	3.51	No	No	0	1	3
553	R:R:F659	R:R:R736	16.03	Yes	No	0	4	5
554	R:R:C663	R:R:C761	5.46	No	No	0	9	9
555	R:R:L667	R:R:Q664	3.99	Yes	Yes	27	5	6
556	R:R:Q664	R:R:Q729	12.8	Yes	Yes	27	6	6
557	R:R:P733	R:R:Q664	3.16	No	Yes	0	9	6
558	R:R:L734	R:R:Q664	2.66	No	Yes	0	6	6
559	R:R:L667	R:R:L725	2.77	Yes	No	27	5	8
560	R:R:L667	R:R:Q729	10.65	Yes	Yes	27	5	6
561	R:R:L725	R:R:W668	5.69	No	No	27	8	6
562	R:R:Q729	R:R:W668	32.86	Yes	No	27	6	6
563	R:R:G671	R:R:L670	1.71	No	No	0	6	8
564	R:R:G671	R:R:S675	3.71	No	No	0	6	9
565	R:R:F674	R:R:K777	6.2	No	No	0	9	9
566	R:R:D721	R:R:S675	2.94	Yes	No	0	9	9
567	R:R:G677	R:R:L676	1.71	No	No	0	7	7
568	R:R:L676	R:R:V718	8.94	No	Yes	0	7	7
569	R:R:G677	R:R:S680	3.71	No	No	42	7	7
570	R:R:G679	R:R:Y678	4.35	No	Yes	0	9	8
571	R:R:M681	R:R:Y678	3.59	No	Yes	0	9	8
572	R:R:F682	R:R:Y678	2.06	No	Yes	0	9	8
573	R:R:L780	R:R:Y678	10.55	No	Yes	0	8	8
574	R:R:L781	R:R:Y678	11.72	No	Yes	0	8	8
575	R:R:I809	R:R:M681	11.66	Yes	No	0	8	9
576	R:R:F682	R:R:W686	2	No	No	0	9	8
577	R:R:F682	R:R:G784	3.01	No	No	0	9	9
578	R:R:L710	R:R:T683	2.95	No	No	0	8	7
579	R:R:T683	R:R:V714	1.59	No	No	0	7	7
580	R:R:I685	R:R:L787	4.28	No	Yes	0	9	9
581	R:R:I685	R:R:I809	2.94	No	Yes	0	9	8
582	R:R:W686	R:R:W687	5.62	No	Yes	0	8	9
583	R:R:T690	R:R:W686	19.41	No	No	0	6	8
584	R:R:V691	R:R:W687	7.36	No	Yes	47	8	9
585	R:R:F692	R:R:W687	2	Yes	Yes	47	8	9
586	R:R:L710	R:R:W687	7.97	No	Yes	0	8	9
587	R:R:T791	R:R:V688	9.52	No	No	0	9	9
588	R:R:H689	R:R:L787	2.57	No	Yes	46	8	9
589	R:R:E790	R:R:H689	17.23	No	No	46	8	8
590	R:R:T690	R:R:V691	1.59	No	No	0	6	8
591	R:R:F692	R:R:V691	7.87	Yes	No	47	8	8
592	R:R:F692	R:R:T796	14.27	Yes	No	0	8	7
593	R:R:F692	R:R:K798	3.72	Yes	No	0	8	7
594	R:R:E706	R:R:P707	3.14	No	No	0	6	8
595	R:R:P707	R:R:Y711	2.78	No	No	0	8	5
596	R:R:G715	R:R:V714	1.84	No	No	0	1	7
597	R:R:V714	R:R:V718	1.6	No	Yes	0	7	7
598	R:R:G719	R:R:V718	1.84	No	Yes	45	3	7
599	R:R:V718	R:R:V722	1.6	Yes	No	45	7	4
600	R:R:G719	R:R:V722	3.68	No	No	45	3	4
601	R:R:D721	R:R:M720	6.93	Yes	No	44	9	6
602	R:R:M720	R:R:Y776	7.18	No	No	44	6	7
603	R:R:D721	R:R:Y776	2.3	Yes	No	44	9	7
604	R:R:L725	R:R:Q729	9.32	No	Yes	27	8	6
605	R:R:A726	R:R:I730	1.62	No	No	0	4	4
606	R:R:W728	R:R:W769	27.18	No	No	0	9	8
607	R:R:D732	R:R:P733	3.22	No	No	0	8	9
608	R:R:D732	R:R:W769	10.05	No	No	0	8	8
609	R:R:C761	R:R:L734	3.17	No	No	0	9	6
610	R:R:L734	R:R:S763	4.5	No	No	0	6	8
611	R:R:H735	R:R:T737	9.58	No	No	0	4	3
612	R:R:I738	R:R:R736	5.01	No	No	0	4	5
613	R:R:I738	R:R:Q757	5.49	No	Yes	0	4	5
614	R:R:E739	R:R:H760	11.08	No	No	0	4	4
615	R:R:Q757	R:R:T740	2.83	Yes	No	0	5	3
616	R:R:F741	R:R:L758	4.87	No	Yes	0	5	5
617	R:R:F741	R:R:S828	2.64	No	No	0	5	6
618	R:R:A742	R:R:K743	4.82	No	No	0	2	1
619	R:R:E744	R:R:I754	10.93	No	No	0	5	5
620	R:R:E744	R:R:P756	3.14	No	No	0	5	5
621	R:R:E745	R:R:P746	1.57	No	Yes	0	2	5
622	R:R:E748	R:R:P746	1.57	No	Yes	0	1	5
623	R:R:P746	R:R:S753	5.34	Yes	No	0	5	2
624	R:R:I754	R:R:P746	20.32	No	Yes	0	5	5
625	R:R:D749	R:R:I750	5.6	No	No	0	4	4
626	R:R:L755	R:R:P756	1.64	Yes	No	0	4	5
627	R:R:E759	R:R:L758	6.63	No	Yes	0	7	5
628	R:R:L758	R:R:Q830	2.66	Yes	No	0	5	5
629	R:R:M766	R:R:S762	3.07	No	No	0	5	5
630	R:R:L770	R:R:M766	8.48	No	No	0	5	5
631	R:R:M766	R:R:M824	2.89	No	No	0	5	5
632	R:R:N767	R:R:T768	10.24	No	No	0	4	5
633	R:R:I772	R:R:T768	4.56	No	No	0	4	5
634	R:R:L770	R:R:W769	9.11	No	No	0	5	8
635	R:R:G771	R:R:Y774	2.9	No	No	0	4	6
636	R:R:F773	R:R:K777	7.44	No	No	0	6	9
637	R:R:A820	R:R:Y774	5.34	No	No	0	7	6
638	R:R:G778	R:R:L781	3.42	No	No	0	7	8
639	R:R:G778	R:R:L782	1.71	No	No	0	7	4
640	R:R:L779	R:R:L782	2.77	No	No	0	6	4
641	R:R:A813	R:R:L781	6.3	No	No	0	7	8
642	R:R:G784	R:R:L787	1.71	No	Yes	0	9	9
643	R:R:I785	W:W:?902	2.79	No	Yes	0	6	0
644	R:R:E790	R:R:L787	2.65	No	Yes	46	8	9
645	R:R:A788	W:W:?902	4.62	No	Yes	0	9	0
646	R:R:T791	R:R:V794	1.59	No	No	0	9	8
647	R:R:K792	R:R:S793	3.06	No	No	0	9	7
648	R:R:K792	S:S:Y691	3.58	No	Yes	11	9	6
649	R:R:K792	W:W:?902	9.65	No	Yes	11	9	0
650	R:R:H802	R:R:S795	2.79	No	No	0	9	7
651	R:R:D801	R:R:I799	7	No	No	22	9	8
652	R:R:D801	R:R:V805	2.92	No	No	22	9	9
653	R:R:H802	R:R:R803	4.51	No	No	0	9	8
654	R:R:R803	S:S:R679	4.26	No	No	0	8	9
655	R:R:A804	R:R:M807	3.22	No	No	0	6	7
656	R:R:A804	R:R:V851	1.7	No	No	0	6	7
657	R:R:G806	R:R:V805	1.84	No	No	22	7	9
658	R:R:I809	R:R:V805	3.07	Yes	No	22	8	9
659	R:R:G806	R:R:I809	3.53	No	Yes	22	7	8
660	R:R:Y810	S:S:M694	3.59	No	No	11	9	6
661	R:R:Y810	S:S:N698	5.81	No	No	0	9	9
662	R:R:Y810	W:W:?902	8.02	No	Yes	11	9	0
663	R:R:I847	R:R:N811	4.25	No	No	0	4	8
664	R:R:N811	S:S:Y697	4.65	No	No	0	8	9
665	R:R:T848	R:R:V812	1.59	No	No	0	8	8
666	R:R:A840	R:R:L815	3.15	No	No	0	6	7
667	R:R:A820	R:R:P821	1.87	No	No	0	7	6
668	R:R:P821	R:R:V822	1.77	No	No	0	6	6
669	R:R:F836	R:R:V822	2.62	No	No	0	6	6
670	R:R:A833	R:R:T823	1.68	No	No	0	5	7
671	R:R:I825	S:S:V719	4.61	No	No	0	6	6
672	R:R:D831	R:R:Q829	6.53	No	No	0	7	5
673	R:R:A832	R:R:A835	1.79	No	No	0	6	5
674	R:R:F836	S:S:V709	2.62	No	No	0	6	6
675	R:R:S838	R:R:V842	1.62	No	No	0	7	5
676	R:R:A840	R:R:I841	3.25	No	Yes	0	6	7
677	R:R:I841	R:R:S844	3.1	Yes	Yes	0	7	7
678	R:R:F843	R:R:I847	6.28	No	No	0	5	4
679	R:R:F843	S:S:Y697	2.06	No	No	0	5	9
680	R:R:S844	R:R:S845	1.63	Yes	No	41	7	8
681	R:R:S844	R:R:T848	3.2	Yes	No	0	7	8
682	R:R:I847	R:R:V850	3.07	No	No	0	4	5
683	R:R:L849	R:R:T848	4.42	Yes	No	0	8	8
684	R:R:L849	R:R:L852	2.77	Yes	No	0	8	7
685	R:R:V850	R:R:V851	6.41	No	No	0	5	7
686	R:R:F853	R:R:L852	8.53	Yes	No	21	9	7
687	R:R:F853	R:R:K856	4.96	Yes	No	0	9	9
688	R:R:P855	R:R:V854	3.53	No	No	0	9	6
689	R:R:I861	R:R:L860	5.71	No	No	0	4	6
690	S:S:P50	S:S:P51	1.95	No	No	0	2	2
691	S:S:P50	S:S:R89	8.65	No	No	0	2	9
692	S:S:F98	S:S:P50	18.78	No	No	0	4	2
693	S:S:S52	S:S:S53	3.26	No	Yes	0	5	4
694	S:S:P54	S:S:S53	3.56	Yes	Yes	0	3	4
695	S:S:S53	S:S:Y97	7.63	Yes	Yes	0	4	8
696	S:S:F98	S:S:S53	6.61	No	Yes	0	4	4
697	S:S:P54	S:S:P55	1.95	Yes	No	0	3	2
698	S:S:L56	S:S:P54	1.64	No	Yes	0	6	3
699	S:S:P54	S:S:Q386	11.05	Yes	Yes	0	3	5
700	S:S:F98	S:S:P55	10.11	No	No	0	4	2
701	S:S:D100	S:S:P55	4.83	No	No	0	3	2
702	S:S:L56	S:S:Y97	10.55	No	Yes	0	6	8
703	S:S:H127	S:S:S57	9.76	Yes	No	0	8	4
704	S:S:L128	S:S:S57	6.01	No	No	0	5	4
705	S:S:I58	S:S:L99	2.85	No	No	0	8	8
706	S:S:I58	S:S:L101	11.42	No	No	0	8	5
707	S:S:M59	S:S:Y104	5.99	Yes	No	49	7	6
708	S:S:A120	S:S:M59	3.22	No	Yes	49	6	7
709	S:S:H127	S:S:M59	19.7	Yes	Yes	0	8	7
710	S:S:M59	S:S:V130	6.09	Yes	No	0	7	6
711	S:S:G60	S:S:L61	1.71	No	No	0	7	6
712	S:S:G60	S:S:M62	1.75	No	No	0	7	8
713	S:S:G60	S:S:L101	1.71	No	No	0	7	5
714	S:S:L61	S:S:V130	2.98	No	No	0	6	6
715	S:S:M62	S:S:P63	3.35	No	Yes	0	8	8
716	S:S:G71	S:S:P63	4.06	No	Yes	0	5	8
717	S:S:G74	S:S:P63	4.06	No	Yes	0	8	8
718	S:S:P63	S:S:T106	3.5	Yes	No	0	8	8
719	S:S:P63	S:S:V134	3.53	Yes	No	0	8	6
720	S:S:E67	S:S:T65	5.64	No	No	0	1	5
721	S:S:G71	S:S:K66	1.74	No	No	0	5	3
722	S:S:G74	S:S:K66	1.74	No	No	0	8	3
723	S:S:K66	S:S:R75	7.43	No	No	0	3	4
724	S:S:I73	S:S:S72	4.64	No	No	0	4	3
725	S:S:G74	S:S:I73	3.53	No	No	0	8	4
726	S:S:L78	S:S:R75	2.43	Yes	No	0	4	4
727	S:S:L78	S:S:V77	2.98	Yes	Yes	0	4	5
728	S:S:V77	S:S:V81	1.6	Yes	No	0	5	7
729	S:S:S352	S:S:V77	1.62	No	Yes	1	6	5
730	S:S:H355	S:S:V77	2.77	Yes	Yes	1	7	5
731	S:S:A358	S:S:V77	1.7	No	Yes	0	7	5
732	S:S:L78	S:S:P79	3.28	Yes	No	0	4	5
733	S:S:E82	S:S:L78	3.98	No	Yes	0	4	4
734	S:S:K345	S:S:P79	5.02	No	No	0	3	5
735	S:S:A80	S:S:Y338	2.67	No	Yes	0	8	7
736	S:S:E82	S:S:I85	2.73	No	No	0	4	6
737	S:S:E341	S:S:L83	2.65	No	No	0	5	7
738	S:S:K345	S:S:L83	2.82	No	No	0	3	7
739	S:S:A84	S:S:Y359	2.67	No	Yes	0	9	9
740	S:S:Q87	S:S:S331	4.33	No	Yes	1	7	8
741	S:S:K333	S:S:Q87	8.14	Yes	No	1	5	7
742	S:S:Q87	S:S:W363	4.38	No	Yes	1	7	8
743	S:S:E91	S:S:L93	10.6	No	No	0	5	6
744	S:S:E91	S:S:R95	4.65	No	No	0	5	4
745	S:S:R95	S:S:S92	2.64	No	No	0	4	5
746	S:S:L93	S:S:L94	5.54	No	No	0	6	9
747	S:S:L93	S:S:Q370	14.64	No	No	0	6	7
748	S:S:L94	S:S:M373	2.83	No	No	0	9	4
749	S:S:P96	S:S:Y97	5.56	No	Yes	0	5	8
750	S:S:I385	S:S:Y97	8.46	No	Yes	48	6	8
751	S:S:Q386	S:S:Y97	5.64	Yes	Yes	48	5	8
752	S:S:L101	S:S:L103	8.3	No	No	0	5	1
753	S:S:R102	S:S:Y104	5.14	No	No	0	2	6
754	S:S:H127	S:S:R102	3.39	Yes	No	0	8	2
755	S:S:A120	S:S:Y104	9.34	No	No	49	6	6
756	S:S:D105	S:S:T106	2.89	No	No	0	8	8
757	S:S:D105	S:S:E107	15.59	No	No	0	8	5
758	S:S:G113	S:S:T106	1.82	No	No	0	6	8
759	S:S:E107	S:S:K112	12.15	No	No	0	5	4
760	S:S:C108	S:S:C135	7.28	No	No	3	7	6
761	S:S:C108	S:S:P136	1.88	No	Yes	3	7	9
762	S:S:N110	S:S:S137	5.96	Yes	No	0	5	4
763	S:S:N110	S:S:V138	2.96	Yes	No	0	5	8
764	S:S:I141	S:S:N110	5.66	No	Yes	0	5	5
765	S:S:G113	S:S:K112	1.74	No	No	0	6	4
766	S:S:A116	S:S:G113	1.95	No	No	0	4	6
767	S:S:L114	S:S:Y118	9.38	No	Yes	0	6	7
768	S:S:F117	S:S:I142	5.02	No	No	0	7	7
769	S:S:F117	S:S:W149	6.01	No	No	0	7	7
770	S:S:D119	S:S:Y123	4.6	No	No	0	5	4
771	S:S:I121	S:S:Y390	10.88	No	No	0	6	8
772	S:S:K122	S:S:Y123	5.97	Yes	No	0	4	4
773	S:S:G124	S:S:P125	4.06	No	No	0	2	7
774	S:S:N126	S:S:P125	1.63	No	No	0	4	7
775	S:S:H127	S:S:P125	6.1	Yes	No	0	8	7
776	S:S:F388	S:S:N126	3.62	Yes	No	0	7	4
777	S:S:F388	S:S:L128	8.53	Yes	No	0	7	5
778	S:S:M129	S:S:V152	3.04	No	No	0	6	5
779	S:S:I365	S:S:M129	4.37	No	No	0	5	6
780	S:S:L369	S:S:M129	2.83	No	No	0	8	6
781	S:S:Q153	S:S:V130	8.6	Yes	No	0	9	6
782	S:S:F131	S:S:L154	4.87	Yes	No	51	7	7
783	S:S:F131	S:S:F156	6.43	Yes	No	0	7	6
784	S:S:F131	S:S:I362	6.28	Yes	No	0	7	6
785	S:S:F131	S:S:I365	2.51	Yes	No	51	7	5
786	S:S:G132	S:S:G133	2.11	No	No	3	9	6
787	S:S:G132	S:S:Q153	1.64	No	Yes	3	9	9
788	S:S:G132	S:S:S155	3.71	No	Yes	3	9	8
789	S:S:G133	S:S:T139	1.82	No	No	0	6	8
790	S:S:G133	S:S:S155	3.71	No	Yes	3	6	8
791	S:S:A157	S:S:V134	3.39	No	No	0	7	6
792	S:S:C135	S:S:P136	1.88	No	Yes	3	6	9
793	S:S:C135	S:S:V138	6.83	No	No	0	6	8
794	S:S:P136	S:S:S137	3.56	Yes	No	0	9	4
795	S:S:P136	S:S:T160	1.75	Yes	Yes	3	9	8
796	S:S:T139	S:S:V138	1.59	No	No	0	8	8
797	S:S:I142	S:S:L146	2.85	No	No	0	7	7
798	S:S:A143	S:S:Y169	9.34	No	No	0	9	7
799	S:S:P170	S:S:Q147	1.58	No	No	52	8	6
800	S:S:Q147	S:S:Y171	16.91	No	No	52	6	6
801	S:S:H393	S:S:N150	6.38	No	No	0	1	8
802	S:S:I399	S:S:V152	3.07	No	No	0	6	5
803	S:S:Q153	S:S:S155	4.33	Yes	Yes	3	9	8
804	S:S:F172	S:S:Q153	7.03	Yes	Yes	3	8	9
805	S:S:I365	S:S:L154	2.85	No	No	51	5	7
806	S:S:F156	S:S:S155	3.96	No	Yes	0	6	8
807	S:S:A358	S:S:F156	2.77	No	No	0	7	6
808	S:S:A158	S:S:T160	1.68	Yes	Yes	3	8	8
809	S:S:A158	S:S:L163	1.58	Yes	Yes	3	8	8
810	S:S:A158	S:S:F172	2.77	Yes	Yes	3	8	8
811	S:S:A158	S:S:R174	5.53	Yes	Yes	3	8	9
812	S:S:T159	S:S:T160	1.57	No	Yes	0	7	8
813	S:S:P161	S:S:T160	1.75	Yes	Yes	3	6	8
814	S:S:L163	S:S:T160	4.42	Yes	Yes	3	8	8
815	S:S:P161	S:S:S178	3.56	Yes	No	3	6	8
816	S:S:N180	S:S:P161	6.52	Yes	Yes	3	6	6
817	S:S:E210	S:S:P161	1.57	No	Yes	0	6	6
818	S:S:Q206	S:S:V162	5.73	No	No	36	6	6
819	S:S:L163	S:S:Y169	4.69	Yes	No	0	8	7
820	S:S:F172	S:S:L163	4.87	Yes	Yes	3	8	8
821	S:S:D165	S:S:K167	6.91	No	No	0	8	2
822	S:S:D165	S:S:K168	11.06	No	No	0	8	5
823	S:S:K166	S:S:P170	1.67	No	No	0	7	8
824	S:S:G420	S:S:K166	1.74	No	No	0	8	7
825	S:S:K168	S:S:Y169	9.55	No	No	0	5	7
826	S:S:P170	S:S:Y171	2.78	No	No	52	8	6
827	S:S:L400	S:S:Y171	3.52	No	No	0	3	6
828	S:S:F172	S:S:R174	2.14	Yes	Yes	3	8	9
829	S:S:F173	S:S:L400	3.65	No	No	0	7	3
830	S:S:F173	S:S:M403	11.2	No	Yes	30	7	5
831	S:S:F173	S:S:F417	7.5	No	No	30	7	9
832	S:S:R174	S:S:S178	6.59	Yes	No	3	9	8
833	S:S:E421	S:S:R174	15.12	No	Yes	0	7	9
834	S:S:T175	S:S:V176	3.17	No	No	1	7	6
835	S:S:T175	S:S:Y357	3.75	No	Yes	1	7	5
836	S:S:R422	S:S:T175	2.59	Yes	No	1	9	7
837	S:S:P177	S:S:V176	3.53	No	No	0	6	6
838	S:S:V176	S:S:Y357	2.52	No	Yes	1	6	5
839	S:S:N180	S:S:S178	5.96	Yes	No	3	6	8
840	S:S:D179	S:S:W284	7.82	No	Yes	0	7	6
841	S:S:N180	S:S:V211	2.96	Yes	No	0	6	6
842	S:S:D214	S:S:N180	4.04	No	Yes	0	5	6
843	S:S:N183	S:S:V182	2.96	No	No	0	9	5
844	S:S:I186	S:S:V182	3.07	No	No	0	7	5
845	S:S:N183	S:S:P184	1.63	No	No	0	9	4
846	S:S:L215	S:S:N183	13.73	No	No	0	8	9
847	S:S:P184	S:S:Y442	5.56	No	Yes	0	4	6
848	S:S:A185	S:S:F428	2.77	No	Yes	31	8	8
849	S:S:A185	S:S:Y442	8.01	No	Yes	31	8	6
850	S:S:K188	S:S:L187	2.82	No	No	0	5	5
851	S:S:K188	S:S:Y442	5.97	No	Yes	0	5	6
852	S:S:D447	S:S:K188	11.06	No	No	0	4	5
853	S:S:L189	S:S:L190	2.77	No	No	0	6	5
854	S:S:L190	S:S:W195	2.28	No	Yes	0	5	9
855	S:S:D223	S:S:K191	5.53	No	No	0	7	5
856	S:S:H192	S:S:Y193	6.53	No	Yes	0	4	8
857	S:S:H192	S:S:L449	3.86	No	No	0	4	7
858	S:S:W195	S:S:Y193	12.54	Yes	Yes	0	9	8
859	S:S:I456	S:S:Y193	3.63	Yes	Yes	53	4	8
860	S:S:F458	S:S:Y193	8.25	No	Yes	53	9	8
861	S:S:K196	S:S:Q194	4.07	No	No	0	5	6
862	S:S:I250	S:S:W195	5.87	No	Yes	0	9	9
863	S:S:Q278	S:S:W195	4.38	No	Yes	0	8	9
864	S:S:P464	S:S:W195	8.11	No	Yes	0	9	9
865	S:S:I224	S:S:K196	10.18	No	No	0	6	5
866	S:S:E225	S:S:R197	8.14	No	No	0	5	6
867	S:S:R197	S:S:V248	7.85	No	No	0	6	7
868	S:S:D466	S:S:R197	3.57	No	No	0	9	6
869	S:S:G199	S:S:V198	1.84	No	No	0	8	8
870	S:S:I226	S:S:V198	6.14	No	No	0	6	8
871	S:S:I250	S:S:V198	3.07	No	No	0	9	8
872	S:S:T200	S:S:T202	1.57	No	No	54	7	6
873	S:S:R212	S:S:T200	18.11	Yes	No	54	5	7
874	S:S:T200	S:S:T229	6.28	No	No	0	7	6
875	S:S:F232	S:S:L201	2.44	No	No	0	7	7
876	S:S:R212	S:S:T202	3.88	Yes	No	54	5	6
877	S:S:S231	S:S:T202	3.2	No	No	0	7	6
878	S:S:Q203	S:S:V205	5.73	Yes	No	0	7	4
879	S:S:F208	S:S:Q203	8.2	Yes	Yes	23	7	7
880	S:S:F232	S:S:Q203	8.2	No	Yes	0	7	7
881	S:S:F255	S:S:Q203	2.34	Yes	Yes	23	8	7
882	S:S:D256	S:S:Q203	10.44	Yes	Yes	23	7	7
883	S:S:F208	S:S:R207	18.17	Yes	No	0	7	5
884	S:S:R207	S:S:W284	6	No	Yes	0	5	6
885	S:S:F208	S:S:F255	2.14	Yes	Yes	23	7	8
886	S:S:D256	S:S:F208	5.97	Yes	Yes	23	7	7
887	S:S:Q254	S:S:V211	2.87	No	No	0	6	6
888	S:S:L215	S:S:R212	3.64	No	Yes	0	8	5
889	S:S:R212	S:S:T216	5.17	Yes	No	0	5	5
890	S:S:I226	S:S:R212	3.76	No	Yes	0	6	5
891	S:S:L215	S:S:L219	5.54	No	No	0	8	6
892	S:S:L219	S:S:V218	2.98	No	No	0	6	3
893	S:S:E222	S:S:G221	4.91	No	No	0	5	3
894	S:S:D223	S:S:I224	2.8	No	No	0	7	6
895	S:S:E225	S:S:I224	4.1	No	No	0	5	6
896	S:S:D228	S:S:S227	5.89	No	No	0	5	4
897	S:S:D228	S:S:L243	4.07	No	No	0	5	8
898	S:S:D228	S:S:N246	14.81	No	No	0	5	6
899	S:S:E230	S:S:S239	4.31	No	No	0	8	6
900	S:S:F232	S:S:P236	8.67	No	Yes	0	7	5
901	S:S:N234	S:S:S233	10.43	No	No	0	4	4
902	S:S:D235	S:S:P236	6.44	No	Yes	55	6	5
903	S:S:C237	S:S:D235	6.22	No	No	55	3	6
904	S:S:C237	S:S:P236	7.53	No	Yes	55	3	5
905	S:S:K262	S:S:P236	3.35	No	Yes	0	5	5
906	S:S:C237	S:S:C266	7.28	No	No	0	3	7
907	S:S:S239	S:S:T238	1.6	No	No	0	6	3
908	S:S:S239	S:S:V240	3.23	No	No	0	6	6
909	S:S:E270	S:S:K241	9.45	No	No	0	5	4
910	S:S:E270	S:S:K244	16.2	No	No	0	5	8
911	S:S:K244	S:S:M272	11.52	No	No	56	8	7
912	S:S:K244	S:S:Y277	2.39	No	Yes	56	8	8
913	S:S:D247	S:S:Y277	4.6	No	Yes	0	8	8
914	S:S:K276	S:S:R249	4.95	No	No	0	7	9
915	S:S:R249	S:S:T468	2.59	No	Yes	0	9	6
916	S:S:D638	S:S:R249	4.76	No	No	0	8	9
917	S:S:I251	S:S:W279	19.97	No	No	0	9	9
918	S:S:G253	S:S:L252	1.71	Yes	No	0	5	6
919	S:S:I280	S:S:L252	4.28	No	No	0	7	6
920	S:S:G253	S:S:Q254	4.93	Yes	No	0	5	6
921	S:S:F255	S:S:G253	3.01	Yes	Yes	0	8	5
922	S:S:G253	S:S:I281	1.76	Yes	No	0	5	6
923	S:S:P282	S:S:Q254	7.9	Yes	No	0	5	6
924	S:S:F255	S:S:V263	6.55	Yes	No	0	8	7
925	S:S:D256	S:S:N258	4.04	Yes	No	23	7	2
926	S:S:D256	S:S:M259	4.16	Yes	No	23	7	4
927	S:S:Q257	S:S:Y285	5.64	No	Yes	4	6	5
928	S:S:Q257	S:S:W289	5.48	No	Yes	4	6	9
929	S:S:M259	S:S:N258	4.21	No	No	23	4	2
930	S:S:A260	S:S:F264	2.77	No	Yes	0	8	7
931	S:S:A260	S:S:W289	2.59	No	Yes	0	8	9
932	S:S:F264	S:S:V263	10.49	Yes	No	0	7	7
933	S:S:A267	S:S:F264	2.77	No	Yes	0	8	7
934	S:S:F264	S:S:W279	12.03	Yes	No	0	7	9
935	S:S:F264	S:S:L307	3.65	Yes	No	4	7	7
936	S:S:F264	S:S:M311	3.73	Yes	Yes	4	7	5
937	S:S:C265	S:S:C302	7.28	No	No	0	9	9
938	S:S:E269	S:S:Y268	3.37	No	Yes	0	5	6
939	S:S:N271	S:S:Y268	3.49	No	Yes	57	3	6
940	S:S:Y268	S:S:Y273	4.96	Yes	No	57	6	5
941	S:S:N306	S:S:Y268	20.93	No	Yes	0	6	6
942	S:S:A310	S:S:Y268	2.67	No	Yes	0	8	6
943	S:S:N271	S:S:Y273	9.3	No	No	57	3	5
944	S:S:M272	S:S:Y277	9.58	No	Yes	56	7	8
945	S:S:G274	S:S:Q459	1.64	No	No	0	8	2
946	S:S:G460	S:S:S275	1.86	No	No	0	4	5
947	S:S:K276	S:S:Y277	20.3	No	Yes	0	7	8
948	S:S:I315	S:S:Q278	2.74	No	No	0	5	8
949	S:S:W279	S:S:Y314	2.89	No	Yes	0	9	5
950	S:S:I281	S:S:P282	6.77	No	Yes	0	6	5
951	S:S:I281	S:S:Y285	3.63	No	Yes	0	6	5
952	S:S:G283	S:S:P282	2.03	No	Yes	0	6	5
953	S:S:P282	S:S:W284	4.05	Yes	Yes	0	5	6
954	S:S:G283	S:S:G316	2.11	No	Yes	0	6	5
955	S:S:D318	S:S:G283	6.71	Yes	No	0	6	6
956	S:S:W284	S:S:Y285	6.75	Yes	Yes	0	6	5
957	S:S:D318	S:S:W284	2.23	Yes	Yes	0	6	6
958	S:S:W289	S:S:Y285	10.61	Yes	Yes	4	9	5
959	S:S:E286	S:S:P287	11	No	No	0	4	2
960	S:S:E436	S:S:P287	1.57	No	No	0	4	2
961	S:S:W289	S:S:W290	17.81	Yes	Yes	4	9	6
962	S:S:M311	S:S:W289	5.82	Yes	Yes	4	5	9
963	S:S:W289	S:S:Y314	2.89	Yes	Yes	4	9	5
964	S:S:E291	S:S:W290	4.36	No	Yes	4	2	6
965	S:S:R304	S:S:W290	4	No	Yes	4	1	6
966	S:S:F431	S:S:W290	7.02	Yes	Yes	4	5	6
967	S:S:E436	S:S:W290	4.36	No	Yes	4	4	6
968	S:S:E291	S:S:R304	18.61	No	No	4	2	1
969	S:S:C302	S:S:L303	1.59	No	No	0	9	6
970	S:S:L303	S:S:N306	16.48	No	No	0	6	6
971	S:S:L308	S:S:R304	4.86	No	No	0	1	1
972	S:S:L307	S:S:M311	4.24	No	Yes	4	7	5
973	S:S:M311	S:S:Y314	5.99	Yes	Yes	4	5	5
974	S:S:F431	S:S:M311	3.73	Yes	Yes	4	5	5
975	S:S:E312	S:S:F431	20.99	No	Yes	4	7	5
976	S:S:D433	S:S:E312	2.6	No	No	4	3	7
977	S:S:E312	S:S:R457	4.65	No	Yes	4	7	1
978	S:S:G313	S:S:Q430	3.29	No	Yes	0	5	9
979	S:S:G316	S:S:Y314	2.9	Yes	Yes	0	5	5
980	S:S:F431	S:S:Y314	3.09	Yes	Yes	4	5	5
981	S:S:G316	S:S:I315	3.53	Yes	No	0	5	5
982	S:S:G316	S:S:V317	1.84	Yes	No	0	5	6
983	S:S:G316	S:S:T429	1.82	Yes	No	0	5	5
984	S:S:F428	S:S:V317	3.93	Yes	No	0	8	6
985	S:S:D318	S:S:F319	4.78	Yes	Yes	0	6	4
986	S:S:D318	S:S:K427	5.53	Yes	No	0	6	5
987	S:S:F319	S:S:K353	4.96	Yes	No	1	4	4
988	S:S:F319	S:S:F354	6.43	Yes	No	1	4	5
989	S:S:F319	S:S:Y357	5.16	Yes	Yes	1	4	5
990	S:S:E320	S:S:P321	9.43	No	No	0	4	4
991	S:S:E320	S:S:T425	5.64	No	No	0	4	3
992	S:S:E320	S:S:K427	8.1	No	No	0	4	5
993	S:S:L322	S:S:P321	3.28	No	No	0	4	4
994	S:S:L322	S:S:V411	2.98	No	Yes	0	4	7
995	S:S:G413	S:S:S323	1.86	No	No	0	9	6
996	S:S:K325	S:S:S324	4.59	No	No	0	3	4
997	S:S:I327	S:S:K325	4.36	No	No	0	3	3
998	S:S:Q326	S:S:T334	2.83	No	Yes	32	4	8
999	S:S:P335	S:S:Q326	7.9	No	No	32	4	4
1000	S:S:Q326	S:S:Q336	8.96	No	No	32	4	3
1001	S:S:G332	S:S:K328	6.97	Yes	No	0	7	2
1002	S:S:S331	S:S:T329	4.8	Yes	No	1	8	7
1003	S:S:G332	S:S:T329	1.82	Yes	No	1	7	7
1004	S:S:I330	S:S:W363	14.09	No	Yes	0	5	8
1005	S:S:I330	S:S:K367	2.91	No	No	0	5	7
1006	S:S:G332	S:S:S331	3.71	Yes	Yes	1	7	8
1007	S:S:K333	S:S:S331	15.3	Yes	Yes	1	5	8
1008	S:S:S331	S:S:Y359	2.54	Yes	Yes	1	8	9
1009	S:S:S331	S:S:W363	2.47	Yes	Yes	1	8	8
1010	S:S:G332	S:S:K333	3.49	Yes	Yes	1	7	5
1011	S:S:K333	S:S:Q337	8.14	Yes	Yes	0	5	5
1012	S:S:P335	S:S:T334	5.25	No	Yes	32	4	8
1013	S:S:Q336	S:S:T334	8.5	No	Yes	32	3	8
1014	S:S:Q337	S:S:T334	14.17	Yes	Yes	0	5	8
1015	S:S:Q336	S:S:R340	8.18	No	No	0	3	2
1016	S:S:Q337	S:S:R340	4.67	Yes	No	0	5	2
1017	S:S:E341	S:S:Q337	3.82	No	Yes	0	5	5
1018	S:S:H355	S:S:Y338	2.18	Yes	Yes	1	7	7
1019	S:S:G356	S:S:Y338	4.35	No	Yes	1	5	7
1020	S:S:Y338	S:S:Y359	15.89	Yes	Yes	1	7	9
1021	S:S:V411	S:S:Y338	2.52	Yes	Yes	1	7	7
1022	S:S:N343	S:S:Y342	5.81	No	No	1	3	7
1023	S:S:R346	S:S:Y342	9.26	Yes	No	1	4	7
1024	S:S:H355	S:S:Y342	15.24	Yes	No	1	7	7
1025	S:S:N343	S:S:R346	6.03	No	Yes	1	3	4
1026	S:S:R346	S:S:V349	3.92	Yes	No	0	4	1
1027	S:S:P351	S:S:R346	7.21	No	Yes	0	3	4
1028	S:S:G348	S:S:S347	3.71	No	No	0	5	3
1029	S:S:G350	S:S:P351	4.06	No	No	0	3	3
1030	S:S:H355	S:S:S352	11.16	Yes	No	1	7	6
1031	S:S:F354	S:S:K353	24.82	No	No	1	5	4
1032	S:S:G356	S:S:H355	4.77	No	Yes	1	5	7
1033	S:S:D360	S:S:G356	1.68	Yes	No	1	9	5
1034	S:S:T412	S:S:Y357	6.24	Yes	Yes	1	9	5
1035	S:S:R422	S:S:Y357	7.2	Yes	Yes	1	9	5
1036	S:S:D360	S:S:Y359	3.45	Yes	Yes	1	9	9
1037	S:S:W363	S:S:Y359	16.4	Yes	Yes	1	8	9
1038	S:S:V411	S:S:Y359	2.52	Yes	Yes	1	7	9
1039	S:S:D360	S:S:G361	1.68	Yes	No	0	9	8
1040	S:S:D360	S:S:G410	3.35	Yes	No	0	9	9
1041	S:S:D360	S:S:V411	8.76	Yes	Yes	1	9	7
1042	S:S:D360	S:S:T412	7.23	Yes	Yes	1	9	9
1043	S:S:G361	S:S:V364	3.68	No	No	0	8	7
1044	S:S:F408	S:S:W363	2	No	Yes	0	9	8
1045	S:S:F408	S:S:V364	5.24	No	No	0	9	7
1046	S:S:V364	S:S:V415	1.6	No	No	0	7	8
1047	S:S:K367	S:S:Q370	4.07	No	No	0	7	7
1048	S:S:A402	S:S:T368	1.68	No	No	0	5	8
1049	S:S:M403	S:S:T368	7.53	Yes	No	0	5	8
1050	S:S:L369	S:S:M373	2.83	No	No	0	8	4
1051	S:S:E374	S:S:Q370	6.37	No	No	0	1	7
1052	S:S:E374	S:S:R371	3.49	No	No	0	1	4
1053	S:S:H382	S:S:M373	2.63	No	No	0	3	4
1054	S:S:A378	S:S:T375	1.68	No	No	0	2	1
1055	S:S:H377	S:S:L376	2.57	Yes	No	0	1	7
1056	S:S:H377	S:S:S379	6.97	Yes	No	0	1	1
1057	S:S:H377	S:S:S380	4.18	Yes	No	0	1	2
1058	S:S:H377	S:S:R381	3.39	Yes	No	0	1	4
1059	S:S:A378	S:S:H382	2.93	No	No	0	2	3
1060	S:S:R384	S:S:S380	5.27	No	No	0	3	2
1061	S:S:R381	S:S:R384	12.79	No	No	0	4	3
1062	S:S:Q383	S:S:Q386	15.36	No	Yes	0	2	5
1063	S:S:D387	S:S:Q383	2.61	No	No	0	4	2
1064	S:S:D387	S:S:R384	4.76	No	No	0	4	3
1065	S:S:I385	S:S:Q386	2.74	No	Yes	48	6	5
1066	S:S:D392	S:S:F388	2.39	No	Yes	50	6	7
1067	S:S:F388	S:S:L395	3.65	Yes	Yes	50	7	6
1068	S:S:D392	S:S:T394	10.12	No	No	0	6	3
1069	S:S:D392	S:S:L395	17.64	No	Yes	50	6	6
1070	S:S:H393	S:S:R397	7.9	No	No	0	1	3
1071	S:S:I398	S:S:T394	3.04	No	No	0	4	3
1072	S:S:G396	S:S:L395	1.71	No	Yes	0	4	6
1073	S:S:I398	S:S:L395	2.85	No	Yes	0	4	6
1074	S:S:G396	S:S:I399	3.53	No	No	0	4	6
1075	S:S:N401	S:S:R397	2.41	No	No	0	4	3
1076	S:S:M403	S:S:T406	4.52	Yes	No	30	5	7
1077	S:S:F417	S:S:M403	2.49	No	Yes	30	9	5
1078	S:S:F408	S:S:T406	2.59	No	No	0	9	7
1079	S:S:F417	S:S:T406	2.59	No	No	30	9	7
1080	S:S:N407	S:S:Q414	11.88	No	No	58	4	3
1081	S:S:N407	S:S:V416	5.91	No	No	58	4	5
1082	S:S:F409	S:S:G410	3.01	No	No	0	2	9
1083	S:S:F409	S:S:G413	6.02	No	No	0	2	9
1084	S:S:T412	S:S:V411	4.76	Yes	Yes	1	9	7
1085	S:S:T412	S:S:V415	3.17	Yes	No	1	9	8
1086	S:S:R422	S:S:T412	7.76	Yes	Yes	1	9	9
1087	S:S:Q414	S:S:V416	2.87	No	No	58	3	5
1088	S:S:R422	S:S:V415	13.08	Yes	No	1	9	8
1089	S:S:M423	S:S:V416	3.04	No	No	0	5	5
1090	S:S:M423	S:S:R418	19.85	No	No	0	5	4
1091	S:S:E421	S:S:G420	1.64	No	No	0	7	8
1092	S:S:G424	S:S:R422	4.5	No	Yes	0	6	9
1093	S:S:G424	S:S:T425	3.64	No	No	0	6	3
1094	S:S:F428	S:S:I426	5.02	Yes	No	31	8	5
1095	S:S:I426	S:S:Y442	3.63	No	Yes	31	5	6
1096	S:S:F428	S:S:Y442	3.09	Yes	Yes	31	8	6
1097	S:S:Q430	S:S:V439	2.87	Yes	No	0	9	6
1098	S:S:I456	S:S:Q430	5.49	Yes	Yes	0	4	9
1099	S:S:Q430	S:S:R457	5.84	Yes	Yes	0	9	1
1100	S:S:E436	S:S:F431	10.49	No	Yes	4	4	5
1101	S:S:Q432	S:S:V437	10.03	No	No	0	7	4
1102	S:S:Q432	S:S:R457	17.52	No	Yes	0	7	1
1103	S:S:D433	S:S:R457	14.29	No	Yes	4	3	1
1104	S:S:V437	S:S:V439	1.6	No	No	0	4	6
1105	S:S:G440	S:S:K438	1.74	Yes	No	0	7	3
1106	S:S:G440	S:S:V439	1.84	Yes	No	0	7	6
1107	S:S:E441	S:S:G440	1.64	No	Yes	0	4	7
1108	S:S:G440	S:S:I451	1.76	Yes	No	0	7	4
1109	S:S:E441	S:S:E450	2.54	No	No	0	4	3
1110	S:S:A444	S:S:Y442	6.67	No	Yes	0	4	6
1111	S:S:N443	S:S:V445	5.91	No	No	0	4	1
1112	S:S:N443	S:S:T448	5.85	No	No	0	4	3
1113	S:S:A446	S:S:T448	1.68	No	No	0	2	3
1114	S:S:I451	S:S:L449	5.71	No	No	0	4	7
1115	S:S:I452	S:S:T455	12.16	No	No	0	1	1
1116	S:S:D454	S:S:T455	4.34	No	No	0	2	1
1117	S:S:F458	S:S:I456	2.51	No	Yes	53	9	4
1118	S:S:F458	S:S:P464	2.89	No	No	0	9	9
1119	S:S:E462	S:S:S461	5.75	No	No	0	3	4
1120	S:S:E462	S:S:P463	1.57	No	No	0	3	5
1121	S:S:P463	S:S:P464	1.95	No	No	0	5	9
1122	S:S:D466	S:S:K465	2.77	No	No	0	9	4
1123	S:S:D466	S:S:K467	11.06	No	No	0	9	5
1124	S:S:I470	S:S:T468	3.04	No	Yes	0	3	6
1125	S:S:S640	S:S:T468	6.4	No	Yes	0	3	6
1126	S:S:I469	S:S:L471	4.28	No	No	8	2	3
1127	S:S:I469	S:S:R637	2.51	No	No	8	2	3
1128	S:S:I469	S:S:I639	13.25	No	Yes	8	2	4
1129	S:S:E472	S:S:I470	2.73	No	No	59	1	3
1130	S:S:I470	S:S:R642	10.02	No	Yes	59	3	4
1131	S:S:I639	S:S:L471	4.28	Yes	No	8	4	3
1132	S:S:E472	S:S:R642	10.47	No	Yes	59	1	4
1133	S:S:I641	S:S:Q473	12.35	Yes	No	0	5	4
1134	S:S:G541	S:S:L474	1.71	Yes	No	0	5	3
1135	S:S:R475	S:S:Y628	5.14	No	Yes	8	4	4
1136	S:S:L645	S:S:R475	7.29	No	No	8	5	4
1137	S:S:G541	S:S:K476	1.74	Yes	No	0	5	4
1138	S:S:I477	S:S:P717	8.47	No	No	0	7	5
1139	S:S:F721	S:S:I477	5.02	Yes	No	0	7	7
1140	S:S:P480	S:S:S478	1.78	Yes	No	7	3	6
1141	S:S:L481	S:S:S478	3	Yes	No	7	5	6
1142	S:S:N718	S:S:S478	4.47	No	No	0	7	6
1143	S:S:L479	S:S:P480	3.28	No	Yes	0	1	3
1144	S:S:L481	S:S:P480	3.28	Yes	Yes	7	5	3
1145	S:S:P480	S:S:S483	1.78	Yes	No	0	3	4
1146	S:S:I484	S:S:P480	6.77	No	Yes	0	3	3
1147	S:S:L481	S:S:L485	4.15	Yes	Yes	7	5	5
1148	S:S:F721	S:S:L481	2.44	Yes	Yes	7	7	5
1149	S:S:S483	S:S:S486	1.63	No	No	0	4	3
1150	S:S:I534	S:S:L485	2.85	Yes	Yes	7	8	5
1151	S:S:F721	S:S:L485	6.09	Yes	Yes	7	7	5
1152	S:S:A725	S:S:L485	1.58	No	Yes	7	6	5
1153	S:S:S486	S:S:T489	1.6	No	Yes	7	3	7
1154	S:S:F535	S:S:S486	2.64	Yes	No	7	6	3
1155	S:S:I490	S:S:T489	3.04	No	Yes	0	1	7
1156	S:S:T489	S:S:Y531	7.49	Yes	Yes	7	7	8
1157	S:S:I534	S:S:T489	3.04	Yes	Yes	7	8	7
1158	S:S:F535	S:S:T489	7.78	Yes	Yes	7	6	7
1159	S:S:G492	S:S:L491	1.71	No	No	0	8	2
1160	S:S:G492	S:S:M495	3.49	No	No	0	8	4
1161	S:S:G492	S:S:Y531	4.35	No	Yes	0	8	8
1162	S:S:M493	S:S:M528	7.22	No	No	0	8	5
1163	S:S:M493	S:S:Y531	3.59	No	Yes	0	8	8
1164	S:S:A532	S:S:M493	1.61	No	No	0	2	8
1165	S:S:I494	S:S:S497	3.1	No	No	0	2	3
1166	S:S:C737	S:S:M495	1.62	No	No	0	4	4
1167	S:S:A496	S:S:M528	1.61	No	No	0	7	5
1168	S:S:C737	S:S:F499	2.79	No	No	11	4	7
1169	S:S:F499	S:S:F740	6.43	No	Yes	0	7	9
1170	S:S:F499	S:S:V741	2.62	No	Yes	11	7	6
1171	S:S:I504	S:S:L500	2.85	No	No	0	6	8
1172	S:S:L500	S:S:N521	4.12	No	No	0	8	8
1173	S:S:F502	S:S:L744	2.44	No	No	0	6	5
1174	S:S:F502	S:S:R748	5.34	No	No	0	6	3
1175	S:S:N503	S:S:P517	4.89	No	No	0	9	9
1176	S:S:K505	S:S:N506	4.2	No	No	0	2	4
1177	S:S:L747	S:S:N506	12.36	No	No	0	6	4
1178	S:S:N508	S:S:R507	3.62	No	No	0	6	7
1179	S:S:R507	S:S:Y518	7.2	No	No	0	7	5
1180	S:S:I512	S:S:N508	2.83	No	No	0	8	6
1181	S:S:K510	S:S:Q509	10.85	No	No	0	8	5
1182	S:S:L511	S:S:Q509	7.99	Yes	No	0	4	5
1183	S:S:I512	S:S:L511	4.28	No	Yes	0	8	4
1184	S:S:L511	S:S:L747	2.77	Yes	No	60	4	6
1185	S:S:I512	S:S:K513	2.91	No	No	0	8	8
1186	S:S:N520	S:S:S515	2.98	No	No	0	9	9
1187	S:S:K574	S:S:S515	4.59	No	No	0	9	9
1188	S:S:K743	S:S:S515	4.59	No	No	0	9	9
1189	S:S:P517	S:S:S516	3.56	No	Yes	0	9	9
1190	S:S:S516	S:S:Y518	2.54	Yes	No	0	9	5
1191	S:S:M519	S:S:S516	7.67	No	Yes	61	6	9
1192	S:S:K574	S:S:S516	3.06	No	Yes	61	9	9
1193	S:S:N520	S:S:P517	1.63	No	No	0	9	9
1194	S:S:K574	S:S:M519	5.76	No	No	61	9	6
1195	S:S:F740	S:S:N520	7.25	Yes	No	0	9	9
1196	S:S:I524	S:S:N521	4.25	No	No	0	7	8
1197	S:S:A567	S:S:I523	4.87	No	No	0	7	8
1198	S:S:A570	S:S:I523	3.25	No	No	0	7	8
1199	S:S:I523	S:S:M571	4.37	No	No	0	8	8
1200	S:S:I524	S:S:L736	5.71	No	No	0	7	7
1201	S:S:G526	S:S:L525	1.71	Yes	No	14	9	3
1202	S:S:L525	S:S:L529	2.77	No	No	14	3	5
1203	S:S:G526	S:S:G527	2.11	Yes	No	0	9	5
1204	S:S:G526	S:S:L529	1.71	Yes	No	14	9	5
1205	S:S:G526	S:S:G563	2.11	Yes	No	14	9	9
1206	S:S:G526	S:S:T566	1.82	Yes	Yes	14	9	7
1207	S:S:A567	S:S:G526	1.95	No	Yes	14	7	9
1208	S:S:G527	S:S:S530	1.86	No	No	0	5	6
1209	S:S:I559	S:S:L529	4.28	No	No	0	4	5
1210	S:S:S732	S:S:Y531	2.54	No	Yes	7	8	8
1211	S:S:T733	S:S:Y531	2.5	Yes	Yes	7	8	8
1212	S:S:A532	S:S:F535	2.77	No	Yes	0	2	6
1213	S:S:I559	S:S:S533	10.84	No	No	0	4	8
1214	S:S:F535	S:S:I534	7.54	Yes	Yes	7	6	8
1215	S:S:F721	S:S:I534	2.51	Yes	Yes	7	7	8
1216	S:S:A725	S:S:I534	1.62	No	Yes	7	6	8
1217	S:S:L536	S:S:R556	6.07	No	Yes	0	6	7
1218	S:S:F537	S:S:R556	20.31	No	Yes	0	5	7
1219	S:S:F537	S:S:F721	2.14	No	Yes	0	5	7
1220	S:S:F721	S:S:G538	4.52	Yes	No	0	7	7
1221	S:S:D540	S:S:L539	13.57	Yes	No	2	8	5
1222	S:S:F549	S:S:L539	2.44	Yes	No	2	4	5
1223	S:S:L539	S:S:R556	3.64	No	Yes	0	5	7
1224	S:S:D540	S:S:G541	1.68	Yes	Yes	2	8	5
1225	S:S:D540	S:S:V544	8.76	Yes	No	2	8	5
1226	S:S:D540	S:S:F549	8.36	Yes	Yes	2	8	4
1227	S:S:D540	S:S:E646	9.09	Yes	No	0	8	6
1228	S:S:G541	S:S:V544	1.84	Yes	No	2	5	5
1229	S:S:F543	S:S:S542	3.96	No	No	0	4	4
1230	S:S:E546	S:S:V544	2.85	No	No	0	1	5
1231	S:S:E546	S:S:T548	15.52	No	No	0	1	2
1232	S:S:T548	S:S:T551	10.99	No	No	0	2	1
1233	S:S:C553	S:S:F549	5.59	Yes	Yes	2	9	4
1234	S:S:F549	S:S:R623	3.21	Yes	No	0	4	6
1235	S:S:C648	S:S:F549	4.19	No	Yes	2	9	4
1236	S:S:D619	S:S:E550	6.5	Yes	No	2	9	3
1237	S:S:E550	S:S:L621	5.3	No	Yes	2	3	6
1238	S:S:E550	S:S:R623	3.49	No	No	0	3	6
1239	S:S:L552	S:S:T551	4.42	No	No	0	4	1
1240	S:S:L552	S:S:R556	2.43	No	Yes	0	4	7
1241	S:S:C553	S:S:R556	13.93	Yes	Yes	0	9	7
1242	S:S:C553	S:S:L621	1.59	Yes	Yes	2	9	6
1243	S:S:C553	S:S:C648	1.82	Yes	No	2	9	9
1244	S:S:T554	S:S:V555	3.17	No	No	0	5	6
1245	S:S:L621	S:S:T554	5.9	Yes	No	0	6	5
1246	S:S:V555	S:S:W558	2.45	No	No	0	6	6
1247	S:S:T557	S:S:T561	1.57	No	Yes	0	4	7
1248	S:S:L612	S:S:W558	4.56	No	No	0	7	6
1249	S:S:T561	S:S:V562	3.17	Yes	No	14	7	6
1250	S:S:D608	S:S:T561	5.78	No	Yes	14	9	7
1251	S:S:G563	S:S:V562	3.68	No	No	14	9	6
1252	S:S:D608	S:S:V562	5.84	No	No	14	9	6
1253	S:S:G563	S:S:T566	1.82	No	Yes	14	9	7
1254	S:S:F568	S:S:Y564	12.38	Yes	No	28	8	9
1255	S:S:K664	S:S:Y564	13.14	No	No	0	9	9
1256	S:S:M668	S:S:Y564	4.79	No	No	28	8	9
1257	S:S:K664	S:S:T565	10.51	No	No	0	9	8
1258	S:S:A567	S:S:T566	1.68	No	Yes	14	7	7
1259	S:S:F568	S:S:F572	11.79	Yes	Yes	28	8	9
1260	S:S:F568	S:S:L667	6.09	Yes	No	28	8	8
1261	S:S:F568	S:S:M668	2.49	Yes	No	28	8	8
1262	S:S:F568	S:S:V696	3.93	Yes	No	0	8	9
1263	S:S:F572	S:S:M571	6.22	Yes	No	0	9	8
1264	S:S:F572	S:S:L667	4.87	Yes	No	28	9	8
1265	S:S:F572	S:S:G671	6.02	Yes	No	0	9	9
1266	S:S:A573	S:S:L597	3.15	No	Yes	0	7	8
1267	S:S:L674	S:S:T575	5.9	No	No	0	9	9
1268	S:S:S689	S:S:T575	1.6	No	No	0	9	9
1269	S:S:L674	S:S:W576	4.56	No	No	0	9	8
1270	S:S:K593	S:S:R577	2.48	No	No	0	6	9
1271	S:S:F582	S:S:V578	2.62	No	No	0	7	9
1272	S:S:E677	S:S:H579	13.54	No	No	0	9	8
1273	S:S:H579	S:S:T678	2.74	No	Yes	62	8	9
1274	S:S:H579	S:S:V681	4.15	No	No	62	8	8
1275	S:S:F582	S:S:I581	5.02	No	No	0	7	8
1276	S:S:I592	S:S:Q595	8.23	No	No	0	7	4
1277	S:S:I600	S:S:M604	2.92	No	No	0	5	6
1278	S:S:M604	S:S:V601	3.04	No	No	0	6	7
1279	S:S:G602	S:S:G603	2.11	No	No	0	1	3
1280	S:S:G602	S:S:L605	5.13	No	No	0	1	5
1281	S:S:L605	S:S:L609	4.15	No	No	0	5	4
1282	S:S:I607	S:S:Y663	20.55	No	No	0	6	5
1283	S:S:D608	S:S:L612	5.43	No	No	0	9	7
1284	S:S:C614	S:S:I611	1.64	No	No	0	4	6
1285	S:S:I611	S:S:V660	3.07	No	No	0	6	5
1286	S:S:I613	S:S:Q616	6.86	No	No	0	4	6
1287	S:S:C614	S:S:W656	3.92	No	Yes	0	4	8
1288	S:S:P620	S:S:W615	6.76	Yes	No	2	9	9
1289	S:S:N650	S:S:W615	5.65	Yes	No	2	8	9
1290	S:S:W615	S:S:W656	14.06	No	Yes	2	9	8
1291	S:S:P620	S:S:Q616	6.32	Yes	No	0	9	6
1292	S:S:P620	S:S:V618	1.77	Yes	No	2	9	4
1293	S:S:R622	S:S:V618	3.92	Yes	No	2	4	4
1294	S:S:D619	S:S:P620	1.61	Yes	Yes	2	9	9
1295	S:S:D619	S:S:L621	2.71	Yes	Yes	2	9	6
1296	S:S:D619	S:S:R622	8.34	Yes	Yes	2	9	4
1297	S:S:L621	S:S:P620	3.28	Yes	Yes	2	6	9
1298	S:S:P620	S:S:R622	4.32	Yes	Yes	2	9	4
1299	S:S:N650	S:S:P620	6.52	Yes	Yes	2	8	9
1300	S:S:N650	S:S:R622	7.23	Yes	Yes	2	8	4
1301	S:S:R622	S:S:T651	14.23	Yes	No	0	4	2
1302	S:S:L644	S:S:V625	5.96	No	No	0	4	4
1303	S:S:E626	S:S:Y628	7.86	No	Yes	0	4	4
1304	S:S:K627	S:S:R642	4.95	No	Yes	0	3	4
1305	S:S:K627	S:S:L644	5.64	No	No	0	3	4
1306	S:S:P643	S:S:Y628	11.13	No	Yes	8	4	4
1307	S:S:L645	S:S:Y628	5.86	No	Yes	8	5	4
1308	S:S:E631	S:S:S629	7.19	No	No	0	5	1
1309	S:S:M630	S:S:P632	1.68	No	Yes	0	1	2
1310	S:S:M630	S:S:R642	12.41	No	Yes	0	1	4
1311	S:S:E631	S:S:P632	1.57	No	Yes	0	5	2
1312	S:S:P632	S:S:P634	1.95	Yes	No	8	2	1
1313	S:S:I641	S:S:P632	8.47	Yes	Yes	8	5	2
1314	S:S:P632	S:S:P643	5.84	Yes	No	8	2	4
1315	S:S:D633	S:S:P634	4.83	No	No	0	3	1
1316	S:S:I641	S:S:P634	1.69	Yes	No	8	5	1
1317	S:S:A635	S:S:G636	1.95	No	No	0	1	5
1318	S:S:A635	S:S:I639	4.87	No	Yes	0	1	4
1319	S:S:I639	S:S:R637	3.76	Yes	No	8	4	3
1320	S:S:I639	S:S:I641	2.94	Yes	Yes	8	4	5
1321	S:S:I641	S:S:P643	5.08	Yes	No	8	5	4
1322	S:S:H647	S:S:R714	21.44	No	No	0	5	3
1323	S:S:H652	S:S:N650	5.1	No	Yes	0	4	8
1324	S:S:N650	S:S:W656	7.91	Yes	Yes	2	8	8
1325	S:S:H652	S:S:T651	2.74	No	No	0	4	2
1326	S:S:F711	S:S:T654	2.59	No	No	0	5	4
1327	S:S:I655	S:S:W656	5.87	No	Yes	0	5	8
1328	S:S:G658	S:S:L657	1.71	No	No	0	4	5
1329	S:S:F711	S:S:L657	4.87	No	No	0	5	5
1330	S:S:G658	S:S:Y661	2.9	No	No	0	4	6
1331	S:S:C703	S:S:Y661	2.69	No	No	0	7	6
1332	S:S:A707	S:S:Y661	5.34	No	No	0	6	6
1333	S:S:K664	S:S:Y663	9.55	No	No	0	9	5
1334	S:S:G665	S:S:M668	5.24	No	No	0	8	8
1335	S:S:A675	S:S:C672	3.61	No	No	0	9	5
1336	S:S:A675	S:S:T678	1.68	No	Yes	0	9	9
1337	S:S:R679	S:S:W676	4	No	No	0	9	8
1338	S:S:T678	S:S:V681	1.59	Yes	No	62	9	8
1339	S:S:S689	S:S:T678	7.99	No	Yes	0	9	9
1340	S:S:I683	S:S:V681	4.61	No	No	0	7	8
1341	S:S:P684	S:S:S682	1.78	No	No	0	6	6
1342	S:S:I683	S:S:P684	1.69	No	No	0	7	6
1343	S:S:L686	S:S:N687	5.49	No	No	0	8	9
1344	S:S:D688	S:S:N687	9.42	No	No	0	9	9
1345	S:S:D688	S:S:Y691	12.64	No	Yes	0	9	6
1346	S:S:I692	S:S:S689	3.1	No	No	0	8	9
1347	S:S:K690	W:W:?902	4.13	No	Yes	0	8	0
1348	S:S:P742	S:S:Y691	11.13	No	Yes	11	9	6
1349	S:S:Y691	W:W:?902	12.6	Yes	Yes	11	6	0
1350	S:S:G693	S:S:I692	1.76	No	No	0	7	8
1351	S:S:I692	S:S:S695	3.1	No	No	0	8	8
1352	S:S:G693	S:S:V696	3.68	No	No	0	7	9
1353	S:S:M694	W:W:?902	13.81	No	Yes	11	6	0
1354	S:S:S695	S:S:V696	3.23	No	No	0	8	9
1355	S:S:S695	S:S:T735	3.2	No	No	0	8	8
1356	S:S:I701	S:S:Y697	3.63	No	No	0	6	9
1357	S:S:M702	S:S:N698	7.01	Yes	No	0	7	9
1358	S:S:G700	S:S:V699	1.84	No	No	0	5	9
1359	S:S:C731	S:S:V699	5.12	No	No	0	7	9
1360	S:S:F730	S:S:M702	2.49	No	Yes	0	4	7
1361	S:S:C731	S:S:M702	1.62	No	Yes	0	7	7
1362	S:S:G706	S:S:I705	3.53	No	No	0	7	6
1363	S:S:A708	S:S:V709	1.7	No	No	0	5	6
1364	S:S:F711	S:S:S710	7.93	No	No	0	5	7
1365	S:S:Q720	S:S:R714	9.35	No	No	0	5	3
1366	S:S:D715	S:S:Q716	2.61	No	No	0	5	5
1367	S:S:P717	S:S:Q716	1.58	No	No	0	5	5
1368	S:S:P717	S:S:Q720	1.58	No	No	0	5	5
1369	S:S:N718	S:S:V719	4.43	No	No	0	7	6
1370	S:S:C722	S:S:I723	3.27	No	No	0	5	5
1371	S:S:C722	S:S:L726	1.59	No	No	0	5	4
1372	S:S:A725	S:S:L726	1.58	No	No	0	6	4
1373	S:S:I728	S:S:V727	3.07	No	No	0	8	5
1374	S:S:I729	S:S:T733	3.04	No	Yes	0	6	8
1375	S:S:S732	S:S:T733	4.8	No	Yes	7	8	8
1376	S:S:I734	S:S:T733	3.04	No	Yes	0	4	8
1377	S:S:F740	S:S:L736	7.31	Yes	No	0	9	7
1378	S:S:C737	S:S:V741	1.71	No	Yes	11	4	6
1379	S:S:L738	W:W:?902	2.7	No	Yes	0	7	0
1380	S:S:F740	S:S:V739	3.93	Yes	No	0	9	8
1381	S:S:P742	S:S:V741	3.53	No	Yes	11	9	6
1382	S:S:I745	S:S:V741	3.07	No	Yes	11	3	6
1383	S:S:I745	S:S:P742	1.69	No	No	11	3	9
1384	R:R:A397	R:R:N399	1.56	No	No	0	4	4
1385	R:R:A433	R:R:N434	1.56	No	No	0	3	4
1386	R:R:I841	R:R:S838	1.55	Yes	No	0	7	7
1387	R:R:I240	R:R:V170	1.54	No	No	0	5	8
1388	R:R:A359	R:R:D358	1.54	No	No	0	8	9
1389	R:R:I685	R:R:V688	1.54	No	No	0	9	9
1390	R:R:I730	R:R:V731	1.54	No	No	0	4	4
1391	R:R:I818	R:R:V814	1.54	No	No	0	7	6
1392	S:S:I659	S:S:V660	1.54	No	No	0	4	5
1393	S:S:I705	S:S:V709	1.54	No	No	0	6	6
1394	S:S:I728	S:S:V724	1.54	No	No	0	8	4
1395	R:R:K373	R:R:S345	1.53	No	No	0	5	5
1396	S:S:K276	S:S:S275	1.53	No	No	0	7	5
1397	S:S:K325	S:S:S323	1.53	No	No	0	3	6
1398	R:R:I550	R:R:T565	1.52	Yes	No	0	7	3
1399	S:S:K70	S:S:V68	1.52	No	No	0	3	2
1400	S:S:M423	S:S:V445	1.52	No	No	0	5	1
1401	S:S:I456	S:S:T455	1.52	Yes	No	0	4	1
1402	S:S:M702	S:S:V727	1.52	Yes	No	0	7	5
1403	R:R:A333	R:R:E302	1.51	No	No	0	5	5
1404	R:R:F674	R:R:G671	1.51	No	No	0	9	6
1405	S:S:A164	S:S:E421	1.51	No	No	0	8	7
1406	S:S:F572	S:S:G569	1.51	Yes	No	0	9	9
1407	R:R:L175	R:R:S218	1.5	No	No	0	6	8
1408	R:R:L495	R:R:S485	1.5	No	No	0	7	4
1409	R:R:G655	R:R:R656	1.5	No	No	0	5	1
1410	R:R:L676	R:R:S675	1.5	No	No	0	7	9
1411	S:S:K467	S:S:T468	1.5	No	Yes	0	5	6
1412	R:R:L211	R:R:V170	1.49	No	No	0	9	8
1413	R:R:L229	R:R:V253	1.49	No	No	0	7	7
1414	R:R:L252	R:R:V253	1.49	No	No	0	5	7
1415	R:R:L326	R:R:V330	1.49	No	No	0	8	7
1416	R:R:L383	R:R:V378	1.49	Yes	Yes	19	7	8
1417	R:R:L839	R:R:V595	1.49	No	Yes	0	3	6
1418	R:R:N800	R:R:S625	1.49	No	Yes	0	9	9
1419	R:R:L815	R:R:V814	1.49	No	No	0	7	6
1420	S:S:L243	S:S:V248	1.49	No	No	0	8	7
1421	S:S:L686	S:S:V578	1.49	No	No	0	8	9
1422	R:R:N811	R:R:V812	1.48	No	No	0	8	8
1423	R:R:L292	R:R:T291	1.47	No	No	0	5	6
1424	R:R:L481	R:R:T484	1.47	No	No	0	8	8
1425	R:R:I818	S:S:I705	1.47	No	No	0	7	6
1426	R:R:L826	S:S:T713	1.47	No	No	0	6	6
1427	S:S:L376	S:S:T375	1.47	No	No	0	7	1
1428	S:S:L511	S:S:T746	1.47	Yes	No	60	4	4
1429	S:S:L522	S:S:T566	1.47	No	Yes	0	5	7
1430	S:S:L560	S:S:T561	1.47	No	Yes	0	7	7
1431	S:S:L712	S:S:T713	1.47	No	No	0	6	6
1432	S:S:L747	S:S:T746	1.47	No	No	60	6	4
1433	S:S:I251	S:S:M272	1.46	No	No	0	9	7
1434	S:S:N389	S:S:T391	1.46	No	No	0	5	4
1435	S:S:I701	S:S:M702	1.46	No	Yes	0	6	7
1436	R:R:I408	R:R:K373	1.45	Yes	No	0	3	5
1437	R:R:D721	R:R:T724	1.45	Yes	No	0	9	6
1438	R:R:G775	R:R:Y774	1.45	No	No	0	4	6
1439	S:S:G221	S:S:Y220	1.45	No	No	0	3	5
1440	S:S:G274	S:S:Y273	1.45	No	No	0	8	5
1441	S:S:I592	S:S:K596	1.45	No	No	0	7	6
1442	R:R:K386	R:R:K387	1.44	No	No	0	5	6
1443	R:R:F659	R:R:P660	1.44	Yes	No	0	4	3
1444	S:S:E286	S:S:S288	1.44	No	No	0	4	3
1445	R:R:I474	R:R:L196	1.43	No	No	0	6	6
1446	R:R:Q658	R:R:V662	1.43	No	No	0	3	5
1447	R:R:I825	R:R:L826	1.43	No	No	0	6	6
1448	S:S:E67	S:S:V68	1.43	No	No	0	1	2
1449	S:S:I729	S:S:L488	1.43	No	No	0	6	4
1450	S:S:I600	S:S:L597	1.43	No	Yes	0	5	8
1451	R:R:G305	R:R:W306	1.41	No	Yes	0	4	9
1452	R:R:E336	S:S:T238	1.41	No	No	0	6	3
1453	R:R:T338	S:S:E230	1.41	No	No	0	4	8
1454	R:R:L717	R:R:M720	1.41	No	No	0	6	6
1455	R:R:K743	R:R:L755	1.41	No	Yes	0	1	4
1456	S:S:L511	S:S:M514	1.41	Yes	No	0	4	7
1457	S:S:K596	S:S:L597	1.41	No	Yes	0	6	8
1458	S:S:K743	S:S:L744	1.41	No	No	0	9	5
1459	S:S:K305	S:S:N306	1.4	No	No	0	4	6
1460	S:S:D594	S:S:I592	1.4	No	No	0	8	7
1461	R:R:H618	R:R:S617	1.39	No	No	0	6	7
1462	R:R:C761	R:R:R736	1.39	No	No	0	9	5
1463	R:R:H760	R:R:S762	1.39	No	No	0	4	5
1464	R:R:L605	R:R:L849	1.38	No	Yes	0	4	8
1465	R:R:L639	R:R:L669	1.38	Yes	Yes	0	6	5
1466	R:R:L639	R:R:L672	1.38	Yes	No	0	6	5
1467	S:S:L146	S:S:L151	1.38	No	No	0	7	7
1468	S:S:L609	S:S:L612	1.38	No	No	0	4	7
1469	R:R:I423	R:R:Q541	1.37	No	No	0	6	9
1470	R:R:I550	R:R:Q541	1.37	Yes	No	0	7	9
1471	S:S:D105	S:S:L64	1.36	No	No	0	8	5
1472	R:R:P183	R:R:W182	1.35	No	Yes	0	4	6
1473	R:R:E336	R:R:K308	1.35	No	No	0	6	7
1474	R:R:E745	R:R:K747	1.35	No	No	0	2	3
1475	R:R:E381	R:R:L383	1.33	No	Yes	0	5	7
1476	S:S:L598	S:S:Q595	1.33	No	No	0	5	4
1477	R:R:N434	R:R:Q444	1.32	No	No	0	4	4
1478	R:R:N502	R:R:Q503	1.32	No	Yes	15	7	3
1479	S:S:N150	S:S:Q147	1.32	No	No	0	8	6
1480	S:S:R577	S:S:S516	1.32	No	Yes	0	9	9
1481	R:R:F659	R:R:V662	1.31	Yes	No	0	4	5
1482	S:S:E339	S:S:N343	1.31	No	No	0	2	3
1483	S:S:R435	S:S:V437	1.31	No	No	0	1	4
1484	S:S:E441	S:S:N443	1.31	No	No	0	4	4
1485	R:R:D497	R:R:E496	1.3	No	No	0	4	4
1486	S:S:A580	S:S:W576	1.3	No	No	0	6	8
1487	S:S:R622	S:S:T624	1.29	Yes	No	0	4	3
1488	R:R:E370	R:R:Q314	1.27	No	No	0	5	8
1489	R:R:V842	R:R:Y846	1.26	No	No	0	5	8
1490	R:R:R356	S:S:I226	1.25	No	No	0	5	6
1491	R:R:F612	R:R:M857	1.24	No	No	0	8	6
1492	S:S:K547	S:S:R623	1.24	No	No	0	1	6
1493	R:R:V428	R:R:W536	1.23	No	No	0	5	3
1494	R:R:L667	R:R:R666	1.21	Yes	No	0	5	8
1495	S:S:N344	S:S:R340	1.21	No	No	0	1	2
1496	S:S:L597	S:S:R577	1.21	Yes	No	0	8	9
1497	R:R:K709	R:R:W708	1.16	No	No	0	7	4
1498	S:S:F501	S:S:F502	1.07	No	No	0	1	6
1499	S:S:F670	S:S:F673	1.07	No	No	0	7	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:G173	2.138	5	0	7
2	R:R:F176	4.118	5	0	7
3	R:R:W182	5.732	5	0	6
4	R:R:R202	7.5225	4	9	5
5	R:R:I205	6.2675	4	9	6
6	R:R:Y209	7.0925	4	33	8
7	R:R:D221	5.535	4	10	6
8	R:R:G223	3.895	4	10	7
9	R:R:Y230	5.514	5	12	7
10	R:R:Y234	4.9	4	12	5
11	R:R:I241	4.025	4	0	7
12	R:R:M243	3.4325	4	0	7
13	R:R:P244	2.05	6	0	8
14	R:R:S248	2.1125	4	10	5
15	R:R:T251	2.6425	4	6	7
16	R:R:M259	3.405	4	12	5
17	R:R:W260	5.48	6	12	7
18	R:R:S266	2.385	4	6	8
19	R:R:G268	2.825	4	6	7
20	R:R:S269	4.1325	4	6	8
21	R:R:S271	3.864	5	6	9
22	R:R:L274	4.50167	6	6	8
23	R:R:R279	9.1425	4	6	6
24	R:R:F280	10.52	4	6	8
25	R:R:F283	4.716	5	6	8
26	R:R:F284	5.19	6	24	6
27	R:R:R285	4.02	4	6	9
28	R:R:H293	4.91	4	0	5
29	R:R:R297	3.9375	4	13	7
30	R:R:W304	9.124	5	13	7
31	R:R:W306	3.72875	8	13	9
32	R:R:Q313	4.81	4	17	7
33	R:R:V318	8.355	4	6	5
34	R:R:F339	6.2925	4	18	6
35	R:R:R340	5.714	5	17	6
36	R:R:Q341	6.63	4	18	7
37	R:R:F344	4.0275	4	36	4
38	R:R:V349	3.5775	4	18	3
39	R:R:P350	5.3375	4	18	7
40	R:R:R372	7.03	4	5	7
41	R:R:F375	5.806	5	19	8
42	R:R:V378	2.46	5	19	8
43	R:R:Y379	11.86	4	5	7
44	R:R:L383	4.1075	4	19	7
45	R:R:F384	6.16	4	5	5
46	R:R:F391	4.6375	4	13	7
47	R:R:I393	3.8375	4	0	5
48	R:R:Y396	3.35	4	0	5
49	R:R:W400	5.28667	6	0	8
50	R:R:D405	8.35	4	5	3
51	R:R:I408	8.1825	4	5	3
52	R:R:E414	9.125	4	5	7
53	R:R:H422	6.7025	4	26	6
54	R:R:S439	4.815	4	9	8
55	R:R:M441	3.322	5	9	5
56	R:R:F446	5.08	4	9	7
57	R:R:P468	2.3625	4	0	5
58	R:R:Y471	6.38429	7	9	9
59	R:R:D472	4.855	4	0	9
60	R:R:W475	6.56167	6	9	8
61	R:R:Y500	6.0575	4	12	8
62	R:R:Q503	5.64	4	15	3
63	R:R:S522	5.55	4	16	9
64	R:R:R533	6.6975	4	16	9
65	R:R:Y547	6.15333	6	26	5
66	R:R:I550	3.986	5	40	7
67	R:R:Y553	5.43167	6	25	6
68	R:R:D554	8.555	4	39	5
69	R:R:W562	11.6025	4	0	5
70	R:R:W568	7.215	4	13	9
71	R:R:P573	8.1325	4	13	5
72	R:R:T578	5.015	4	37	6
73	R:R:F592	7.286	5	20	5
74	R:R:V595	1.8325	4	20	6
75	R:R:N613	7.13	4	21	9
76	R:R:S625	3.385	4	22	9
77	R:R:L639	2.8275	4	43	6
78	R:R:V644	2.6725	4	20	8
79	R:R:D650	7.735	4	29	9
80	R:R:F659	5.89	4	0	4
81	R:R:Q664	5.6525	4	27	6
82	R:R:L667	4.655	4	27	5
83	R:R:L669	1.545	4	0	5
84	R:R:Y678	6.454	5	0	8
85	R:R:W687	5.7375	4	47	9
86	R:R:F692	6.965	4	47	8
87	R:R:V718	3.495	4	45	7
88	R:R:D721	3.405	4	44	9
89	R:R:Q729	16.4075	4	27	6
90	R:R:P746	7.2	4	0	5
91	R:R:L755	3.6825	4	0	4
92	R:R:Q757	6.3625	4	0	5
93	R:R:L758	4.755	4	0	5
94	R:R:L787	2.8025	4	46	9
95	R:R:I809	5.3	4	22	8
96	R:R:I841	2.38	4	0	7
97	R:R:S844	2.4125	4	41	7
98	R:R:L849	2.978	5	0	8
99	R:R:F853	8.762	5	21	9
100	S:S:S53	5.265	4	0	4
101	S:S:P54	4.55	4	0	3
102	S:S:M59	8.75	4	49	7
103	S:S:P63	3.7	5	0	8
104	S:S:V77	2.134	5	1	5
105	S:S:L78	3.1675	4	0	4
106	S:S:Y97	7.568	5	48	8
107	S:S:N110	4.96	4	0	5
108	S:S:Y118	5.605	4	0	7
109	S:S:K122	5.58	4	12	4
110	S:S:H127	9.7375	4	0	8
111	S:S:F131	5.0225	4	51	7
112	S:S:P136	2.2675	4	3	9
113	S:S:Q153	5.4	4	3	9
114	S:S:S155	3.9275	4	3	8
115	S:S:A158	2.89	4	3	8
116	S:S:T160	2.234	5	3	8
117	S:S:P161	3.35	4	3	6
118	S:S:L163	3.89	4	3	8
119	S:S:F172	4.2025	4	3	8
120	S:S:R174	7.345	4	3	9
121	S:S:N180	4.87	4	3	6
122	S:S:Y193	7.7375	4	53	8
123	S:S:W195	6.636	5	0	9
124	S:S:Q203	6.982	5	23	7
125	S:S:F208	8.62	4	23	7
126	S:S:R212	6.912	5	54	5
127	S:S:P236	6.4975	4	55	5
128	S:S:G253	2.8525	4	0	5
129	S:S:F255	3.51	4	23	8
130	S:S:D256	6.1525	4	23	7
131	S:S:F264	5.90667	6	4	7
132	S:S:Y268	7.084	5	57	6
133	S:S:Y277	9.2175	4	56	8
134	S:S:P282	5.1875	4	0	5
135	S:S:W284	5.37	5	0	6
136	S:S:Y285	6.6575	4	4	5
137	S:S:W289	7.53333	6	4	9
138	S:S:W290	7.51	5	4	6
139	S:S:M311	4.702	5	4	5
140	S:S:Y314	3.552	5	4	5
141	S:S:G316	2.44	5	0	5
142	S:S:D318	4.8125	4	0	6
143	S:S:F319	5.3325	4	1	4
144	S:S:S331	5.525	6	1	8
145	S:S:G332	3.9975	4	1	7
146	S:S:K333	8.7675	4	1	5
147	S:S:T334	7.6875	4	32	8
148	S:S:Q337	7.7	4	0	5
149	S:S:Y338	5.522	5	1	7
150	S:S:R346	6.605	4	1	4
151	S:S:H355	7.224	5	1	7
152	S:S:Y357	4.974	5	1	5
153	S:S:Y359	7.245	6	1	9
154	S:S:D360	4.35833	6	1	9
155	S:S:W363	7.868	5	1	8
156	S:S:H377	4.2775	4	0	1
157	S:S:Q386	8.6975	4	48	5
158	S:S:F388	4.5475	4	50	7
159	S:S:L395	6.4625	4	50	6
160	S:S:M403	6.435	4	30	5
161	S:S:V411	4.308	5	1	7
162	S:S:T412	5.832	5	1	9
163	S:S:R422	7.026	5	1	9
164	S:S:F428	3.7025	4	31	8
165	S:S:Q430	4.3725	4	0	9
166	S:S:F431	9.064	5	4	5
167	S:S:G440	1.745	4	0	7
168	S:S:Y442	5.48833	6	31	6
169	S:S:I456	3.2875	4	53	4
170	S:S:R457	10.575	4	4	1
171	S:S:T468	3.3825	4	0	6
172	S:S:P480	3.378	5	7	3
173	S:S:L481	3.2175	4	7	5
174	S:S:L485	3.6675	4	7	5
175	S:S:T489	4.59	5	7	7
176	S:S:L511	3.584	5	60	4
177	S:S:S516	3.63	5	61	9
178	S:S:G526	1.90167	6	14	9
179	S:S:Y531	4.094	5	7	8
180	S:S:I534	3.512	5	7	8
181	S:S:F535	5.1825	4	7	6
182	S:S:D540	8.292	5	2	8
183	S:S:G541	1.7425	4	2	5
184	S:S:F549	4.758	5	2	4
185	S:S:C553	5.7325	4	2	9
186	S:S:R556	9.276	5	0	7
187	S:S:T561	2.9975	4	14	7
188	S:S:T566	1.6975	4	14	7
189	S:S:F568	7.336	5	28	8
190	S:S:F572	6.082	5	28	9
191	S:S:L597	1.8	4	0	8
192	S:S:D619	4.79	4	2	9
193	S:S:P620	4.36857	7	2	9
194	S:S:L621	3.756	5	2	6
195	S:S:R622	6.555	6	2	4
196	S:S:Y628	7.4975	4	8	4
197	S:S:P632	3.902	5	8	2
198	S:S:I639	5.82	5	8	4
199	S:S:I641	6.106	5	8	5
200	S:S:R642	9.4625	4	59	4
201	S:S:N650	6.482	5	2	8
202	S:S:W656	7.94	4	2	8
203	S:S:T678	3.5	4	62	9
204	S:S:Y691	9.9875	4	11	6
205	S:S:M702	2.82	5	0	7
206	S:S:F721	3.78667	6	7	7
207	S:S:T733	3.345	4	7	8
208	S:S:F740	6.23	4	0	9
209	S:S:V741	2.7325	4	11	6
210	W:W:?902	7.29	8	11	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G173	R:R:L242	10.0559	1.71	Yes	No	0	7	6
2	R:R:L265	R:R:M243	10.4851	5.65	No	Yes	0	6	7
3	R:R:L242	R:R:P244	10.3036	1.64	No	Yes	0	6	8
4	R:R:P244	R:R:S266	18.9398	1.78	Yes	Yes	0	8	8
5	R:R:G268	R:R:S266	20.681	1.86	Yes	Yes	6	7	8
6	R:R:G268	R:R:W182	17.202	2.81	Yes	Yes	0	7	6
7	R:R:W182	R:R:W395	21.6566	14.06	Yes	No	0	6	5
8	R:R:F283	R:R:L274	28.295	8.53	Yes	Yes	6	8	8
9	R:R:L274	R:R:S271	21.1487	3	Yes	Yes	6	8	9
10	R:R:F283	R:R:S266	19.9928	2.64	Yes	Yes	6	8	8
11	R:R:F280	R:R:L274	48.5212	7.31	Yes	Yes	6	8	8
12	R:R:E255	R:R:F280	47.8216	8.16	No	Yes	6	8	8
13	R:R:E255	S:S:N110	48.1857	5.26	No	Yes	0	8	5
14	R:R:G268	R:R:H287	10.0056	4.77	Yes	No	0	7	7
15	R:R:I361	R:R:W306	10.9213	9.4	No	Yes	13	9	9
16	R:R:I337	R:R:R340	12.1059	3.76	No	Yes	17	6	6
17	R:R:I309	R:R:I337	11.9058	4.42	No	No	0	8	6
18	R:R:I309	R:R:I361	11.7067	5.89	No	No	0	8	9
19	R:R:P350	R:R:V351	52.6956	1.77	Yes	No	0	7	8
20	R:R:V351	R:R:V378	52.7732	1.6	No	Yes	0	8	8
21	R:R:F375	R:R:V378	37.7943	3.93	Yes	Yes	19	8	8
22	R:R:F375	R:R:W400	36.0847	2	Yes	Yes	0	8	8
23	R:R:W400	R:R:Y396	26.1454	1.93	Yes	Yes	0	8	5
24	R:R:I393	R:R:Y396	20.4624	6.04	Yes	Yes	0	5	5
25	R:R:I393	R:R:W395	21.6841	4.7	Yes	No	0	5	5
26	R:R:G364	R:R:V363	14.6073	3.68	No	No	0	6	7
27	R:R:T311	R:R:V363	14.4807	1.59	No	No	0	7	7
28	R:R:T316	R:R:V318	25.052	4.76	No	Yes	0	5	5
29	R:R:Q314	R:R:T316	25.0058	9.92	No	No	0	8	5
30	R:R:F343	R:R:Q314	25.0172	2.34	No	No	0	7	8
31	R:R:T315	R:R:T320	10.2185	1.57	No	No	0	6	7
32	R:R:F343	R:R:P347	25.0409	5.78	No	No	0	7	6
33	R:R:P347	R:R:V374	25.1416	1.77	No	No	0	6	7
34	R:R:P350	R:R:V349	51.3462	3.53	Yes	Yes	18	7	3
35	R:R:V349	S:S:T216	51.4976	3.17	Yes	No	0	3	5
36	R:R:L383	R:R:V378	100	1.49	Yes	Yes	19	7	8
37	R:R:L383	R:R:Y388	99.5724	9.38	Yes	No	19	7	8
38	R:R:K387	R:R:Y388	99.5548	8.36	No	No	0	6	8
39	R:R:K387	R:R:R360	99.1944	13.61	No	No	0	6	9
40	R:R:R360	R:R:T578	98.9418	5.17	No	Yes	37	9	6
41	R:R:S753	R:R:T578	98.3433	1.6	No	Yes	0	2	6
42	R:R:S753	R:R:V580	97.5554	1.62	No	No	0	2	4
43	R:R:L755	R:R:V580	97.4618	7.45	Yes	No	0	4	4
44	R:R:K582	R:R:L755	97.2937	4.23	No	Yes	0	1	4
45	R:R:K582	R:R:Q757	97.1989	5.42	No	Yes	0	1	5
46	R:R:F584	R:R:Q757	92.9	11.71	No	Yes	0	4	5
47	R:R:F584	R:R:F586	92.7949	2.14	No	No	0	4	4
48	R:R:F586	R:R:Y652	92.584	2.06	No	No	0	4	4
49	R:R:Q589	R:R:Y652	92.3722	7.89	No	No	0	2	4
50	R:R:F592	R:R:Q589	92.2659	14.05	Yes	No	0	5	2
51	R:R:F592	R:R:V644	90.8337	2.62	Yes	Yes	20	5	8
52	R:R:S838	R:R:V644	90.6308	4.85	No	Yes	0	7	8
53	R:R:I841	R:R:S838	90.1913	1.55	Yes	No	0	7	7
54	R:R:I841	R:R:S844	87.0113	3.1	Yes	Yes	0	7	7
55	R:R:F853	R:R:L852	26.8148	8.53	Yes	No	21	9	7
56	R:R:L849	R:R:L852	31.0803	2.77	Yes	No	0	8	7
57	R:R:C637	R:R:L849	14.6549	1.59	No	Yes	0	5	8
58	R:R:C637	R:R:S844	14.7236	1.72	No	Yes	41	5	7
59	R:R:L849	R:R:T848	17.6363	4.42	Yes	No	0	8	8
60	R:R:S844	R:R:T848	70.8687	3.2	Yes	No	0	7	8
61	R:R:F853	R:R:K856	22.6478	4.96	Yes	No	0	9	9
62	R:R:K856	R:R:S625	22.264	3.06	No	Yes	0	9	9
63	R:R:D801	R:R:S625	21.1047	5.89	No	Yes	22	9	9
64	R:R:D801	R:R:V805	20.7262	2.92	No	No	22	9	9
65	R:R:I809	R:R:V805	19.95	3.07	Yes	No	22	8	9
66	R:R:I809	R:R:M681	16.4437	11.66	Yes	No	0	8	9
67	R:R:M681	R:R:Y678	16.0564	3.59	No	Yes	0	9	8
68	R:R:F682	R:R:Y678	12.9548	2.06	No	Yes	0	9	8
69	R:R:F682	R:R:W686	12.592	2	No	No	0	9	8
70	R:R:W686	R:R:W687	11.4175	5.62	No	Yes	0	8	9
71	R:R:T848	R:R:V812	59.3331	1.59	No	No	0	8	8
72	R:R:N811	R:R:V812	59.184	1.48	No	No	0	8	8
73	R:R:N811	S:S:Y697	58.0973	4.65	No	No	0	8	9
74	S:S:I701	S:S:Y697	57.9757	3.63	No	No	0	6	9
75	S:S:I701	S:S:M702	57.8239	1.46	No	Yes	0	6	7
76	S:S:M702	S:S:N698	56.6016	7.01	Yes	No	0	7	9
77	R:R:Y810	S:S:N698	56.4477	5.81	No	No	0	9	9
78	R:R:Y810	W:W:?902	56.1047	8.02	No	Yes	11	9	0
79	S:S:Y691	W:W:?902	54.9847	12.6	Yes	Yes	11	6	0
80	S:S:P742	S:S:Y691	53.9535	11.13	No	Yes	11	9	6
81	S:S:P742	S:S:V741	53.6049	3.53	No	Yes	11	9	6
82	S:S:C737	S:S:V741	44.6933	1.71	No	Yes	11	4	6
83	S:S:C737	S:S:M495	45.7754	1.62	No	No	0	4	4
84	S:S:G492	S:S:M495	45.6059	3.49	No	No	0	8	4
85	S:S:G492	S:S:Y531	45.2662	4.35	No	Yes	0	8	8
86	S:S:T489	S:S:Y531	43.5279	7.49	Yes	Yes	7	7	8
87	S:S:I534	S:S:T489	40.6307	3.04	Yes	Yes	7	8	7
88	S:S:F721	S:S:I534	38.0961	2.51	Yes	Yes	7	7	8
89	S:S:N110	S:S:V138	32.0182	2.96	Yes	No	0	5	8
90	S:S:T139	S:S:V138	31.6769	1.59	No	No	0	8	8
91	S:S:G133	S:S:T139	31.5141	1.82	No	No	0	6	8
92	S:S:G133	S:S:S155	25.1939	3.71	No	Yes	3	6	8
93	S:S:F156	S:S:S155	21.4901	3.96	No	Yes	0	6	8
94	S:S:F131	S:S:F156	13.9496	6.43	Yes	No	0	7	6
95	S:S:F131	S:S:I365	13.2578	2.51	Yes	No	51	7	5
96	S:S:I365	S:S:M129	13.0412	4.37	No	No	0	5	6
97	S:S:L369	S:S:M129	11.965	2.83	No	No	0	8	6
98	S:S:L369	S:S:M373	11.7849	2.83	No	No	0	8	4
99	S:S:H382	S:S:M373	14.3739	2.63	No	No	0	3	4
100	S:S:A378	S:S:H382	14.1566	2.93	No	No	0	2	3
101	S:S:A378	S:S:T375	13.9391	1.68	No	No	0	2	1
102	S:S:L376	S:S:T375	13.7214	1.47	No	No	0	7	1
103	S:S:H377	S:S:L376	13.5034	2.57	Yes	No	0	1	7
104	S:S:D387	S:S:R384	12.175	4.76	No	No	0	4	3
105	S:S:D387	S:S:Q383	11.7271	2.61	No	No	0	4	2
106	S:S:Q383	S:S:Q386	11.279	15.36	No	Yes	0	2	5
107	S:S:Q153	S:S:V130	14.8488	8.6	Yes	No	0	9	6
108	S:S:N110	S:S:S137	16.0067	5.96	Yes	No	0	5	4
109	S:S:P136	S:S:S137	15.8722	3.56	Yes	No	0	9	4
110	S:S:P136	S:S:T160	15.8709	1.75	Yes	Yes	3	9	8
111	S:S:P161	S:S:T160	13.2348	1.75	Yes	Yes	3	6	8
112	S:S:N180	S:S:P161	17.2152	6.52	Yes	Yes	3	6	6
113	S:S:N180	S:S:V211	19.1574	2.96	Yes	No	0	6	6
114	S:S:Q254	S:S:V211	19.2601	2.87	No	No	0	6	6
115	S:S:P282	S:S:Q254	13.9356	7.9	Yes	No	0	5	6
116	S:S:G283	S:S:P282	15.5809	2.03	No	Yes	0	6	5
117	S:S:D318	S:S:G283	25.816	6.71	Yes	No	0	6	6
118	S:S:D318	S:S:F319	23.8784	4.78	Yes	Yes	0	6	4
119	S:S:F319	S:S:Y357	23.0404	5.16	Yes	Yes	1	4	5
120	S:S:T412	S:S:Y357	20.0241	6.24	Yes	Yes	1	9	5
121	S:S:D360	S:S:T412	10.0778	7.23	Yes	Yes	1	9	9
122	S:S:R212	S:S:T216	51.5154	5.17	Yes	No	0	5	5
123	S:S:L215	S:S:R212	23.9249	3.64	No	Yes	0	8	5
124	S:S:L215	S:S:N183	23.7303	13.73	No	No	0	8	9
125	S:S:N183	S:S:P184	23.5399	1.63	No	No	0	9	4
126	S:S:P184	S:S:Y442	23.4868	5.56	No	Yes	0	4	6
127	S:S:G283	S:S:G316	39.0965	2.11	No	Yes	0	6	5
128	S:S:G316	S:S:V317	23.3201	1.84	Yes	No	0	5	6
129	S:S:F428	S:S:V317	23.2836	3.93	Yes	No	0	8	6
130	S:S:I226	S:S:R212	28.7821	3.76	No	Yes	0	6	5
131	S:S:I226	S:S:V198	28.6719	6.14	No	No	0	6	8
132	S:S:I250	S:S:V198	28.5633	3.07	No	No	0	9	8
133	S:S:I250	S:S:W195	28.5131	5.87	No	Yes	0	9	9
134	S:S:I251	S:S:W279	20.1945	19.97	No	No	0	9	9
135	S:S:I251	S:S:M272	19.8267	1.46	No	No	0	9	7
136	S:S:M272	S:S:Y277	18.336	9.58	No	Yes	56	7	8
137	S:S:K276	S:S:Y277	17.6149	20.3	No	Yes	0	7	8
138	S:S:K276	S:S:R249	16.5059	4.95	No	No	0	7	9
139	S:S:R249	S:S:T468	15.7654	2.59	No	Yes	0	9	6
140	S:S:G316	S:S:Y314	26.5061	2.9	Yes	Yes	0	5	5
141	S:S:W279	S:S:Y314	18.4125	2.89	No	Yes	0	9	5
142	S:S:G316	S:S:I315	23.8222	3.53	Yes	No	0	5	5
143	S:S:I315	S:S:Q278	23.7931	2.74	No	No	0	5	8
144	S:S:F537	S:S:F721	35.236	2.14	No	Yes	0	5	7
145	S:S:F537	S:S:R556	35.0536	20.31	No	Yes	0	5	7
146	S:S:C553	S:S:R556	31.7169	13.93	Yes	Yes	0	9	7
147	S:S:C553	S:S:L621	30.8931	1.59	Yes	Yes	2	9	6
148	S:S:L621	S:S:T554	25.5945	5.9	Yes	No	0	6	5
149	S:S:T554	S:S:V555	25.4006	3.17	No	No	0	5	6
150	S:S:V555	S:S:W558	25.2065	2.45	No	No	0	6	6
151	S:S:L612	S:S:W558	25.0121	4.56	No	No	0	7	6
152	S:S:D608	S:S:L612	24.0368	5.43	No	No	0	9	7
153	S:S:D608	S:S:V562	23.2136	5.84	No	No	14	9	6
154	S:S:G563	S:S:V562	23.0556	3.68	No	No	14	9	6
155	S:S:G526	S:S:G563	11.9536	2.11	Yes	No	14	9	9
156	S:S:A567	S:S:G526	10.5263	1.95	No	Yes	14	7	9
157	S:S:G563	S:S:T566	10.905	1.82	No	Yes	14	9	7
158	S:S:A567	S:S:T566	10.4972	1.68	No	Yes	14	7	7
159	S:S:A567	S:S:I523	20.6088	4.87	No	No	0	7	8
160	S:S:I523	S:S:M571	19.7785	4.37	No	No	0	8	8
161	S:S:F572	S:S:M571	19.3631	6.22	Yes	No	0	9	8
162	S:S:F568	S:S:F572	17.694	11.79	Yes	Yes	28	8	9
163	S:S:F568	S:S:V696	14.3592	3.93	Yes	No	0	8	9
164	S:S:I692	S:S:S689	11.835	3.1	No	No	0	8	9
165	R:R:V374	R:R:V378	25.2631	1.6	No	Yes	0	7	8
166	S:S:F428	S:S:Y442	23.062	3.09	Yes	Yes	31	8	6
167	S:S:Q278	S:S:W195	23.7939	4.38	No	Yes	0	8	9
168	R:R:M243	R:R:P244	14.3302	1.68	Yes	Yes	0	7	8
169	R:R:S271	R:R:V318	23.5609	8.08	Yes	Yes	6	9	5
170	R:R:F366	R:R:G364	14.3095	3.01	No	No	0	8	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I785	W:W:?902	2.79	0	No	Yes	6	0	1	0
R:R:A788	W:W:?902	4.62	0	No	Yes	9	0	1	0
R:R:K792	R:R:S793	3.06	11	No	No	9	7	1	2
R:R:K792	S:S:Y691	3.58	11	No	Yes	9	6	1	1
R:R:K792	W:W:?902	9.65	11	No	Yes	9	0	1	0
R:R:Y810	S:S:M694	3.59	11	No	No	9	6	1	1
R:R:Y810	S:S:N698	5.81	11	No	No	9	9	1	2
R:R:Y810	W:W:?902	8.02	11	No	Yes	9	0	1	0
S:S:D688	S:S:Y691	12.64	0	No	Yes	9	6	2	1
S:S:K690	W:W:?902	4.13	0	No	Yes	8	0	1	0
S:S:P742	S:S:Y691	11.13	11	No	Yes	9	6	2	1
S:S:Y691	W:W:?902	12.6	11	Yes	Yes	6	0	1	0
S:S:M694	W:W:?902	13.81	11	No	Yes	6	0	1	0
S:S:L738	W:W:?902	2.7	0	No	Yes	7	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
88.89	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
55.56	Single	7EB2	rac-BHFF	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
43.75	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
37.50	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
31.58	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
30.77	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
30.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
28.57	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
28.57	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
27.78	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
27.27	Single	8ZPN	Cholesterol	8ZPN-CXCR4-AMD3100-Cholesterol
26.67	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
26.32	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
25.00	Single	8ZPL	Cholesterol	8ZPL-CXCR4-HF51116-Cholesterol
25.00	Single	8ZPM	Cholesterol	8ZPM-CXCR4-AMD070-Cholesterol
23.53	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
23.08	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
23.08	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
22.22	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
21.43	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
21.43	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
21.43	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
20.00	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
20.00	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
20.00	Single	8ZPM	Cholesterol	8ZPM-CXCR4-AMD070-Cholesterol
18.75	Single	7RBT	PubChem 163183774	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8PKM	t7m	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
15.79	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
15.38	Single	8XQP	Aristolochic acid A	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
14.29	Single	8HNN	SCH546738	8HNN-CXCR3-SCH546738
13.33	Single	8PJK	t7m	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
13.33	Single	8XQN	Aristolochic acid A	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
13.33	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
12.50	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
11.76	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
11.76	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
11.11	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
10.00	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
9.09	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
8.70	Single	8FN0	PubChem 118610427	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
7.14	Single	8Y69	Cholesterol	8Y69-LGR4-R-spondin-2-Cholesterol-ZNRF3
6.67	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
6.67	Single	8Y69	Cholesterol	8Y69-LGR4-R-spondin-2-Cholesterol-ZNRF3
6.25	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
6.25	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/β1/γ2
5.88	Single	5X7D	PubChem 129318963	5X7D-β₂-S-Carazolol-PubChem 129318963
5.56	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
5.56	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
5.26	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
5.26	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/β1/γ2
4.76	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon

PDB Summary
PDB	7CA3
Class	C
SubFamily	Aminoacid
Type	GABAB
SubType	GABAB1; GABAB2
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	rac-BHFF
Protein Partners	-
PDB Resolution	4.5
Date	2020-11-11
D.O.I.	10.1016/j.jmb.2020.09.023

Net Summary
I_min	1.57
Number of Linked Nodes	1269
Number of Links	1499
Number of Hubs	210
Number of Links mediated by Hubs	778
Number of Communities	62
Number of Nodes involved in Communities	366
Number of Links involved in Communities	469

Path Summary
Number Of Nodes in MetaPath	171
Number Of Links MetaPath	170
Number of Shortest Paths	1705290
Length Of Smallest Path	3
Average Path Length	38.8217
Length of Longest Path	101
Minimum Path Strength	1.265
Average Path Strength	5.0607
Maximum Path Strength	22.83
Minimum Path Correlation	0.7
Average Path Correlation	0.995047
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.5
Average % Of Corr. Nodes	62.2669
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.2585
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• regulation of biological process • signaling • biological regulation • cell-cell signaling • neuron-glial cell signaling • cellular process • cell communication • cellular response to stimulus • regulation of cellular process • response to stimulus • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • trans-synaptic signaling • synaptic transmission, GABAergic • chemical synaptic transmission • synaptic signaling • anterograde trans-synaptic signaling • gamma-aminobutyric acid signaling pathway • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein-containing complex • plasma membrane protein complex • membrane protein complex • receptor complex
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein-containing complex • plasma membrane protein complex • membrane protein complex • receptor complex • GABA receptor complex • G protein-coupled receptor dimeric complex • plasma membrane signaling receptor complex • G protein-coupled receptor complex • G protein-coupled GABA receptor complex • extracellular region • Schaffer collateral - CA1 synapse • G protein-coupled receptor heterodimeric complex • presynapse • presynaptic membrane • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • intracellular anatomical structure • cytoplasm • GABA-ergic synapse • protein heterodimerization activity • protein binding • binding • protein dimerization activity • G protein-coupled GABA receptor activity • GABA receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • regulation of biological process • signaling • biological regulation • cell-cell signaling • neuron-glial cell signaling • cellular process • cell communication • gamma-aminobutyric acid signaling pathway • regulation of molecular function • negative regulation of lyase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • cellular response to stimulus • regulation of cellular process • response to stimulus • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • synaptic transmission, GABAergic
SCOP2	Domain Identifier	• Type 1 solute binding protein-like
SCOP2	Family Identifier	• Type 1 solute binding protein-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	FN0
PDB Residues	W:W:?902
Environment Details	Open EMBL-EBI Page
Code	FN0
Name	(3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one
Synonyms
Identifier
Formula	C17 H21 F3 O3
Molecular Weight	330.342
SMILES
PubChem	7023848
Formal Charge	0
Total Atoms	44
Total Chiral Atoms	1
Total Bonds	45
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9UBS5
Sequence	>7CA3_Chain_R R R A V Y I G A L F P M S G G W P G G Q A C Q P A V E M A L E D V N S R R D I L P D Y E L K L I H H D S K C D P G Q A T K Y L Y E L L Y N D P I K I I L M P G C S S V S T L V A E A A R M W N L I V L S Y G S S S P A L S N R Q R F P T F F R T H P S A T L H N P T R V K L F E K W G W K K I A T I Q Q T T E V F T S T L D D L E E R V K E A G I E I T F R Q S F F S D P A V P V K N L K R Q D A R I I V G L F Y E T E A R K V F C E V Y K E R L F G K K Y V W F L I G W Y A D N W F K I Y D P S I N C T V D E M T E A V E G H I T T E I V M L N P A N T R S I S N M T S Q E F V E K L T K R L T G G F Q E A P L A Y D A I W A L A L A L N K T S R L E D F N Y N N Q T I T D Q I Y R A M N S S S F E G V S G H V V F D A S G S R M A W T L I E Q L Q G G S Y K K I G Y Y D S T K D D L S W S K T D K W I G G S P P A D Q T L V I K T F R F L S Q K L F I S V S V L S S L G I V L A V V C L S F N I Y N S H V R Y I Q N S Q P N L N N L T A V G C S L A L A A V F P L G L D G Y H I G R N Q F P F V C Q A R L W L L G L G F S L G Y G S M F T K I W W V H T V F T E P W K L Y A T V G L L V G M D V L T L A I W Q I V D P L H R T I E T F A K E E P K E D I D V S I L P Q L E H C S S R K M N T W L G I F Y G Y K G L L L L L G I F L A Y E T K S V S T E K I N D H R A V G M A I Y N V A V L C L I T A P V T M I L S S Q Q D A A F A F A S L A I V F S S Y I T L V V L F V P K M R R L I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	O75899
Sequence	>7CA3_Chain_S P P S S P P L S I M G L M P L T K E V A K G S I G R G V L P A V E L A I E Q I R N E S L L R P Y F L D L R L Y D T E C D N A K G L K A F Y D A I K Y G P N H L M V F G G V C P S V T S I I A E S L Q G W N L V Q L S F A A T T P V L A D K K K Y P Y F F R T V P S D N A V N P A I L K L L K H Y Q W K R V G T L T Q D V Q R F S E V R N D L T G V L Y G E D I E I S D T E S F S N D P C T S V K K L K G N D V R I I L G Q F D Q N M A A K V F C C A Y E E N M Y G S K Y Q W I I P G W Y E P S W W E C L R K N L L A A M E G Y I G V D F E P L S S K Q I K T I S G K T P Q Q Y E R E Y N N K R S G V G P S K F H G Y A Y D G I W V I A K T L Q R A M E T L H A S S R H Q R I Q D F N Y T D H T L G R I I L N A M N E T N F F G V T G Q V V F R N G E R M G T I K F T Q F Q D S R E V K V G E Y N A V A D T L E I I N D T I R F Q G S E P P K D K T I I L E Q L R K I S L P L Y S I L S A L T I L G M I M A S A F L F F N I K N R N Q K L I K M S S P Y M N N L I I L G G M L S Y A S I F L F G L D G S F V S E K T F E T L C T V R T W I L T V G Y T T A F G A M F A K T W R V H A I F K I K D Q K L L V I V G G M L L I D L C I L I C W Q A V D P L R R T V E K Y S M E P D P A G R D I S I R P L L E H C E N T H M T I W L G I V Y A Y K G L L M L F G C F L A W E T R N V S I P A L N D S K Y I G M S V Y N V G I M C I I G A A V S F L T R D Q P N V Q F C I V A L V I I F C S T I T L C L V F V P K L I T L R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7EB2	C	Aminoacid	GABAB	GABAB2; GABAB1	Homo sapiens	Baclofen	rac-BHFF	Gi1/β1/γ2	3.5	2021-05-05	10.1038/s41586-021-03507-1
	7EB2 (No Gprot)	C	Aminoacid	GABAB	GABAB2; GABAB1	Homo sapiens	Baclofen	rac-BHFF		3.5	2021-05-05	10.1038/s41586-021-03507-1
	7CUM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	Phospholipid	-	3.52	2020-11-11	10.1016/j.jmb.2020.09.023
	7CA5	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	7.6	2020-11-11	10.1016/j.jmb.2020.09.023
	6W2Y	C	Aminoacid	GABAB	GABAB1; GABAB1	Homo sapiens	PubChem 5311042	PubChem 23727970	-	3.2	2020-07-01	10.1038/s41586-020-2469-4
	7C7S	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	-	-	2.9	2020-07-01	10.1038/s41422-020-0350-5
	7C7Q	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	Baclofen	PubChem 7023848	-	3	2020-07-01	10.1038/s41422-020-0350-5
	6WIV	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	PubChem 52923113; PubChem 52924645	-	3.3	2020-07-01	10.1038/s41586-020-2452-0
	6W2X	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	PubChem 5311042	PubChem 23727970	-	3.6	2020-07-01	10.1038/s41586-020-2469-4
	6VJM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	3.97	2020-06-10	10.1038/s41586-020-2408-4
	6UOA	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	6.3	2020-06-10	10.1038/s41586-020-2408-4
	6UO9	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	-	-	4.8	2020-06-10	10.1038/s41586-020-2408-4
	6UO8	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	GS39783	-	3.63	2020-06-10	10.1038/s41586-020-2408-4

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