psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	H:H:?1	R:R:F80	11.98	No	No	3	0	4
2	H:H:?1	R:R:N82	25.79	No	No	3	0	4
3	H:H:?1	R:R:Y101	6.29	No	Yes	3	0	5
4	R:R:P90	R:R:V30	5.3	Yes	No	2	4	2
5	R:R:S136	R:R:V30	3.23	No	No	2	1	2
6	R:R:P137	R:R:V30	8.84	Yes	No	2	3	2
7	R:R:E34	R:R:S31	5.75	No	No	0	4	4
8	R:R:L32	R:R:P137	3.28	No	Yes	0	4	3
9	R:R:L32	R:R:Q140	5.32	No	No	0	4	4
10	R:R:E34	R:R:W33	4.36	No	No	0	4	3
11	R:R:L379	R:R:W33	2.28	Yes	No	0	3	3
12	R:R:E34	R:R:K38	2.7	No	No	0	4	4
13	R:R:K38	R:R:T35	3	No	No	0	4	5
14	R:R:P137	R:R:T35	3.5	Yes	No	0	3	5
15	R:R:K38	R:R:W87	4.64	No	Yes	0	4	3
16	R:R:F66	R:R:W39	6.01	Yes	No	2	7	5
17	R:R:E68	R:R:W39	2.18	No	No	2	4	5
18	R:R:W39	R:R:Y88	18.33	No	Yes	2	5	5
19	R:R:R40	R:R:R43	8.53	No	Yes	0	2	4
20	R:R:R40	R:R:R44	5.33	No	Yes	0	2	3
21	R:R:E41	R:R:R44	5.82	No	Yes	0	4	3
22	R:R:E41	R:R:Q45	7.65	No	No	2	4	5
23	R:R:E41	R:R:W87	4.36	No	Yes	2	4	3
24	R:R:F66	R:R:Y42	3.09	Yes	Yes	2	7	6
25	R:R:C71	R:R:Y42	4.03	No	Yes	0	9	6
26	R:R:P86	R:R:Y42	11.13	Yes	Yes	2	8	6
27	R:R:W87	R:R:Y42	15.43	Yes	Yes	2	3	6
28	R:R:Y42	R:R:Y88	8.94	Yes	Yes	2	6	5
29	R:R:C46	R:R:R43	2.79	No	Yes	2	8	4
30	R:R:Q47	R:R:R43	5.84	No	Yes	0	3	4
31	R:R:L50	R:R:R43	2.43	No	Yes	0	4	4
32	R:R:F66	R:R:R43	18.17	Yes	Yes	2	7	4
33	R:R:Q47	R:R:R44	8.18	No	Yes	0	3	3
34	R:R:R44	R:R:R48	10.66	Yes	No	0	3	4
35	R:R:Q45	R:R:R48	2.34	No	No	0	5	4
36	R:R:Q45	R:R:W87	12.05	No	Yes	2	5	3
37	R:R:C46	R:R:F66	5.59	No	Yes	2	8	7
38	R:R:C46	R:R:C71	7.28	No	No	0	8	9
39	R:R:E52	R:R:R48	15.12	No	No	0	2	4
40	R:R:D53	R:R:S49	2.94	No	No	0	3	2
41	R:R:L50	R:R:R64	3.64	No	Yes	0	4	4
42	R:R:D53	R:R:P54	4.83	No	No	0	3	2
43	R:R:D53	R:R:R64	3.57	No	Yes	0	3	4
44	R:R:P54	R:R:P55	1.95	No	No	0	2	1
45	R:R:P55	R:R:P56	1.95	No	Yes	0	1	1
46	R:R:P55	R:R:R64	2.88	No	Yes	0	1	4
47	R:R:P56	R:R:T58	5.25	Yes	No	4	1	1
48	R:R:F61	R:R:P56	10.11	Yes	Yes	4	3	1
49	R:R:D74	R:R:P56	9.66	No	Yes	4	3	1
50	R:R:F61	R:R:T58	6.49	Yes	No	4	3	1
51	R:R:D59	R:R:L60	4.07	No	No	0	3	1
52	R:R:G108	R:R:L60	3.42	No	No	0	9	1
53	R:R:F61	R:R:N63	2.42	Yes	No	0	3	4
54	R:R:D74	R:R:F61	2.39	No	Yes	4	3	3
55	R:R:C62	R:R:G75	1.96	No	No	2	9	7
56	R:R:C104	R:R:C62	7.28	No	No	2	9	9
57	R:R:C62	R:R:W110	16.98	No	Yes	2	9	9
58	R:R:D74	R:R:R64	16.68	No	Yes	0	3	4
59	R:R:R102	R:R:T65	3.88	Yes	No	0	8	5
60	R:R:E68	R:R:F66	7	No	Yes	2	4	7
61	R:R:D67	R:R:Y69	5.75	Yes	Yes	2	9	6
62	R:R:D67	R:R:W72	4.47	Yes	Yes	2	9	9
63	R:R:D67	R:R:R102	3.57	Yes	Yes	2	9	8
64	R:R:D67	R:R:R121	5.96	Yes	Yes	2	9	6
65	R:R:A70	R:R:Y69	4	No	Yes	2	5	6
66	R:R:P86	R:R:Y69	8.34	Yes	Yes	2	8	6
67	R:R:Y69	R:R:Y88	4.96	Yes	Yes	2	6	5
68	R:R:L89	R:R:Y69	3.52	Yes	Yes	2	5	6
69	R:R:R121	R:R:Y69	16.46	Yes	Yes	2	6	6
70	R:R:L123	R:R:Y69	3.52	Yes	Yes	2	5	6
71	R:R:D215	R:R:Y69	3.45	No	Yes	2	3	6
72	R:R:A70	R:R:W72	3.89	No	Yes	2	5	9
73	R:R:A70	R:R:P86	3.74	No	Yes	2	5	8
74	R:R:V81	R:R:W72	2.45	No	Yes	0	6	9
75	R:R:V83	R:R:W72	13.48	No	Yes	0	5	9
76	R:R:V100	R:R:W72	2.45	No	Yes	2	7	9
77	R:R:R102	R:R:W72	21.99	Yes	Yes	2	8	9
78	R:R:R121	R:R:W72	3	Yes	Yes	2	6	9
79	R:R:P73	R:R:V81	3.53	No	No	0	5	6
80	R:R:C104	R:R:G75	3.92	No	No	2	9	7
81	R:R:G75	R:R:W110	2.81	No	Yes	2	7	9
82	R:R:E76	R:R:P77	3.14	No	No	0	1	4
83	R:R:E76	R:R:S79	10.06	No	No	0	1	5
84	R:R:F103	R:R:G78	4.52	Yes	No	0	4	7
85	R:R:F103	R:R:F80	10.72	Yes	No	3	4	4
86	R:R:F80	R:R:W120	5.01	No	Yes	3	4	5
87	R:R:V81	R:R:W110	6.13	No	Yes	0	6	9
88	R:R:N82	R:R:Y101	17.44	No	Yes	3	4	5
89	R:R:C85	R:R:P86	3.77	Yes	Yes	2	9	8
90	R:R:C85	R:R:G98	3.92	Yes	No	2	9	4
91	R:R:C85	R:R:V100	3.42	Yes	No	2	9	7
92	R:R:C126	R:R:C85	7.28	No	Yes	2	9	9
93	R:R:P86	R:R:Y88	12.52	Yes	Yes	2	8	5
94	R:R:L89	R:R:P86	4.93	Yes	Yes	2	5	8
95	R:R:L89	R:R:Y88	3.52	Yes	Yes	2	5	5
96	R:R:L89	R:R:P90	4.93	Yes	Yes	2	5	4
97	R:R:L89	R:R:W91	9.11	Yes	Yes	2	5	4
98	R:R:P90	R:R:W91	4.05	Yes	Yes	2	4	4
99	R:R:P90	R:R:S135	5.34	Yes	Yes	2	4	1
100	R:R:P137	R:R:P90	7.79	Yes	Yes	2	3	4
101	R:R:E127	R:R:W91	2.18	No	Yes	0	2	4
102	R:R:S135	R:R:W91	3.71	Yes	Yes	2	1	4
103	R:R:E138	R:R:W91	6.54	No	Yes	2	2	4
104	R:R:S94	R:R:V95	3.23	No	No	0	4	5
105	R:R:C126	R:R:V95	3.42	No	No	0	9	5
106	R:R:H99	R:R:Q97	3.71	No	No	0	4	4
107	R:R:C126	R:R:G98	1.96	No	No	2	9	4
108	R:R:H99	R:R:Y101	10.89	No	Yes	3	4	5
109	R:R:E125	R:R:H99	16	No	No	3	5	4
110	R:R:R121	R:R:V100	2.62	Yes	No	2	6	7
111	R:R:W120	R:R:Y101	1.93	Yes	Yes	3	5	5
112	R:R:D122	R:R:Y101	5.75	No	Yes	3	7	5
113	R:R:E125	R:R:Y101	11.22	No	Yes	3	5	5
114	R:R:R102	R:R:W110	18.99	Yes	Yes	2	8	9
115	R:R:P119	R:R:R102	10.09	Yes	Yes	2	6	8
116	R:R:F103	R:R:T105	2.59	Yes	Yes	3	4	4
117	R:R:F103	R:R:L111	3.65	Yes	No	3	4	4
118	R:R:F103	R:R:W120	2	Yes	Yes	3	4	5
119	R:R:C104	R:R:W110	2.61	No	Yes	2	9	9
120	R:R:E107	R:R:T105	8.47	No	Yes	3	5	4
121	R:R:L109	R:R:T105	4.42	No	Yes	3	5	4
122	R:R:L111	R:R:T105	2.95	No	Yes	3	4	4
123	R:R:E107	R:R:L109	2.65	No	No	3	5	5
124	R:R:P119	R:R:W110	2.7	Yes	Yes	2	6	9
125	R:R:L111	R:R:W120	5.69	No	Yes	3	4	5
126	R:R:P119	R:R:Q112	3.16	Yes	No	0	6	3
127	R:R:D114	R:R:S117	8.83	No	No	0	4	7
128	R:R:N115	R:R:S116	2.98	No	No	0	4	5
129	R:R:S116	R:R:Y220	6.36	No	No	0	5	3
130	R:R:L118	R:R:P119	4.93	No	Yes	0	4	6
131	R:R:L118	R:R:S219	9.01	No	No	0	4	5
132	R:R:D122	R:R:W120	5.58	No	Yes	3	7	5
133	R:R:L123	R:R:R121	23.08	Yes	Yes	2	5	6
134	R:R:H212	R:R:R121	14.67	No	Yes	2	3	6
135	R:R:D215	R:R:R121	3.57	No	Yes	2	3	6
136	R:R:D122	R:R:S124	10.31	No	No	0	7	5
137	R:R:E127	R:R:L123	3.98	No	Yes	0	2	5
138	R:R:H212	R:R:L123	15.43	No	Yes	2	3	5
139	R:R:E125	R:R:S124	7.19	No	No	0	5	5
140	R:R:E127	R:R:Q211	19.11	No	No	0	2	4
141	R:R:P137	R:R:S135	5.34	Yes	Yes	2	3	1
142	R:R:E138	R:R:S135	5.75	No	Yes	2	2	1
143	R:R:P137	R:R:S136	3.56	Yes	No	2	3	1
144	R:R:F143	R:R:Q140	7.03	No	No	0	4	4
145	R:R:F143	R:R:I147	3.77	No	No	0	4	6
146	R:R:I147	R:R:L144	2.85	No	No	0	6	6
147	R:R:L144	R:R:S389	9.01	No	No	0	6	5
148	R:R:Y145	R:R:Y148	8.94	Yes	Yes	1	5	7
149	R:R:T149	R:R:Y145	7.49	No	Yes	1	7	5
150	R:R:D198	R:R:Y145	5.75	No	Yes	0	7	5
151	R:R:L201	R:R:Y145	2.34	No	Yes	0	7	5
152	R:R:T149	R:R:Y148	3.75	No	Yes	1	7	7
153	R:R:Y148	R:R:Y152	7.94	Yes	Yes	1	7	7
154	R:R:V194	R:R:Y148	6.31	No	Yes	1	7	7
155	R:R:G151	R:R:V150	1.84	No	No	0	8	5
156	R:R:G151	R:R:S392	3.71	No	No	1	8	9
157	R:R:F393	R:R:G151	9.03	No	No	1	7	8
158	R:R:S155	R:R:Y152	2.54	No	Yes	0	9	7
159	R:R:R190	R:R:Y152	7.2	Yes	Yes	1	8	7
160	R:R:V194	R:R:Y152	16.4	No	Yes	1	7	7
161	R:R:S392	R:R:Y152	8.9	No	Yes	1	9	7
162	R:R:F393	R:R:L154	2.44	No	No	0	7	5
163	R:R:L154	R:R:L396	4.15	No	No	0	5	7
164	R:R:G395	R:R:S155	3.71	No	No	0	9	9
165	R:R:F156	R:R:V160	7.87	Yes	No	5	7	3
166	R:R:F156	R:R:I188	7.54	Yes	Yes	5	7	7
167	R:R:A191	R:R:F156	4.16	No	Yes	0	7	7
168	R:R:F156	R:R:L192	2.44	Yes	No	0	7	3
169	R:R:A158	R:R:L396	3.15	No	No	0	7	7
170	R:R:A158	R:R:F404	2.77	No	No	0	7	8
171	R:R:I188	R:R:L159	4.28	Yes	No	0	7	9
172	R:R:A399	R:R:L159	4.73	No	No	0	8	9
173	R:R:I188	R:R:V160	4.61	Yes	No	5	7	3
174	R:R:A162	R:R:F184	2.77	No	Yes	0	9	8
175	R:R:A162	R:R:C403	3.61	No	No	0	9	9
176	R:R:A162	R:R:F404	2.77	No	No	0	9	8
177	R:R:F184	R:R:S163	5.28	Yes	No	0	8	6
178	R:R:I188	R:R:S163	3.1	Yes	No	0	7	6
179	R:R:C403	R:R:I165	6.55	No	Yes	0	9	8
180	R:R:I165	R:R:V409	3.07	Yes	Yes	1	8	9
181	R:R:E412	R:R:I165	4.1	Yes	Yes	1	8	8
182	R:R:L166	R:R:L172	5.54	Yes	Yes	1	8	9
183	R:R:L166	R:R:N177	12.36	Yes	Yes	1	8	9
184	R:R:L166	R:R:L181	8.3	Yes	No	0	8	6
185	R:R:F184	R:R:L166	4.87	Yes	Yes	1	8	8
186	R:R:L167	R:R:L181	6.92	No	No	0	3	6
187	R:R:F169	R:R:L172	3.65	No	Yes	1	7	9
188	R:R:E412	R:R:F169	20.99	Yes	No	1	8	7
189	R:R:H171	R:R:R170	4.51	No	No	0	7	8
190	R:R:L172	R:R:N177	5.49	Yes	Yes	1	9	9
191	R:R:L172	R:R:V409	2.98	Yes	Yes	1	9	9
192	R:R:E412	R:R:L172	2.65	Yes	Yes	1	8	9
193	R:R:H173	R:R:Y178	6.53	No	No	0	7	6
194	R:R:C174	R:R:R176	2.79	No	Yes	1	8	9
195	R:R:C174	R:R:N177	4.72	No	Yes	1	8	9
196	R:R:T175	R:R:Y250	2.5	No	Yes	0	7	8
197	R:R:E262	R:R:T175	9.88	No	No	0	6	7
198	R:R:N177	R:R:R176	10.85	Yes	Yes	1	9	9
199	R:R:H180	R:R:R176	3.39	Yes	Yes	1	9	9
200	R:R:R176	R:R:Y250	8.23	Yes	Yes	1	9	8
201	R:R:L349	R:R:R176	7.29	Yes	Yes	1	9	9
202	R:R:N406	R:R:R176	6.03	Yes	Yes	1	9	9
203	R:R:E408	R:R:R176	3.49	Yes	Yes	1	9	9
204	R:R:F266	R:R:Y178	4.13	Yes	No	0	6	6
205	R:R:I179	R:R:W243	3.52	Yes	Yes	1	8	9
206	R:R:E247	R:R:I179	5.47	Yes	Yes	1	9	8
207	R:R:I179	R:R:Y250	7.25	Yes	Yes	1	8	8
208	R:R:F266	R:R:I179	5.02	Yes	Yes	1	6	8
209	R:R:I179	R:R:Y269	3.63	Yes	Yes	1	8	7
210	R:R:F184	R:R:H180	3.39	Yes	Yes	1	8	9
211	R:R:E247	R:R:H180	12.31	Yes	Yes	1	9	9
212	R:R:H180	R:R:L349	7.71	Yes	Yes	1	9	9
213	R:R:H180	R:R:Y402	15.24	Yes	Yes	1	9	8
214	R:R:N182	R:R:W243	20.34	No	Yes	1	9	9
215	R:R:F266	R:R:N182	2.42	Yes	No	1	6	9
216	R:R:N182	R:R:W274	11.3	No	Yes	1	9	9
217	R:R:F187	R:R:L183	2.44	Yes	Yes	1	8	9
218	R:R:L183	R:R:W243	3.42	Yes	Yes	1	9	9
219	R:R:E247	R:R:L183	7.95	Yes	Yes	1	9	9
220	R:R:L183	R:R:V398	2.98	Yes	Yes	1	9	9
221	R:R:L183	R:R:Y402	2.34	Yes	Yes	1	9	8
222	R:R:F184	R:R:V398	2.62	Yes	Yes	1	8	9
223	R:R:F184	R:R:Y402	2.06	Yes	Yes	1	8	8
224	R:R:A185	R:R:W274	2.59	No	Yes	0	3	9
225	R:R:A239	R:R:S186	3.42	No	No	1	8	9
226	R:R:N240	R:R:S186	7.45	No	No	1	9	9
227	R:R:S186	R:R:W274	2.47	No	Yes	1	9	9
228	R:R:F187	R:R:R190	2.14	Yes	Yes	1	8	8
229	R:R:F187	R:R:N240	26.58	Yes	No	1	8	9
230	R:R:F187	R:R:Q394	8.2	Yes	Yes	1	8	9
231	R:R:F187	R:R:G395	4.52	Yes	No	0	8	9
232	R:R:F187	R:R:V398	5.24	Yes	Yes	1	8	9
233	R:R:L189	R:R:L192	4.15	No	No	0	7	3
234	R:R:C236	R:R:R190	4.18	No	Yes	0	5	8
235	R:R:R190	R:R:V237	3.92	Yes	No	0	8	6
236	R:R:N240	R:R:R190	7.23	No	Yes	1	9	8
237	R:R:Q394	R:R:R190	11.68	Yes	Yes	1	9	8
238	R:R:C193	R:R:L232	4.76	No	No	0	6	5
239	R:R:C193	R:R:C233	1.82	No	No	0	6	6
240	R:R:F196	R:R:V229	3.93	No	No	0	5	7
241	R:R:K197	R:R:V229	10.62	No	No	0	6	7
242	R:R:C233	R:R:K197	4.85	No	No	0	6	6
243	R:R:A200	R:R:Q221	7.58	No	No	0	4	4
244	R:R:M204	R:R:W203	4.65	Yes	No	0	3	3
245	R:R:L217	R:R:M204	9.9	No	Yes	0	4	3
246	R:R:M204	R:R:Y220	7.18	Yes	No	0	3	3
247	R:R:Q213	R:R:Y205	3.38	No	No	0	4	3
248	R:R:W214	R:R:Y205	20.26	No	No	0	1	3
249	R:R:L217	R:R:Y205	2.34	No	No	0	4	3
250	R:R:A208	R:R:Q213	3.03	No	No	0	4	4
251	R:R:Q210	R:R:Q213	16.64	No	No	0	4	4
252	R:R:G216	R:R:S219	1.86	No	No	0	2	5
253	R:R:L224	R:R:Y220	7.03	No	No	0	3	3
254	R:R:A225	R:R:Q221	4.55	No	No	0	3	4
255	R:R:D222	R:R:S223	2.94	No	No	0	6	4
256	R:R:L224	R:R:S223	4.5	No	No	0	3	4
257	R:R:L224	R:R:R227	4.86	No	No	0	3	8
258	R:R:C226	R:R:C296	7.28	No	Yes	0	9	9
259	R:R:F230	R:R:Q234	4.68	No	No	1	5	7
260	R:R:F230	R:R:W284	5.01	No	Yes	1	5	8
261	R:R:C296	R:R:F230	4.19	Yes	No	0	9	5
262	R:R:L231	R:R:V281	2.98	No	Yes	1	5	6
263	R:R:L231	R:R:W284	2.28	No	Yes	1	5	8
264	R:R:L231	R:R:W297	2.28	No	Yes	1	5	8
265	R:R:L232	R:R:Y235	2.34	No	Yes	0	5	9
266	R:R:Q234	R:R:W284	3.29	No	Yes	1	7	8
267	R:R:I309	R:R:Q234	4.12	Yes	No	1	7	7
268	R:R:W274	R:R:Y235	7.72	Yes	Yes	0	9	9
269	R:R:P277	R:R:Y235	4.17	Yes	Yes	0	9	9
270	R:R:L278	R:R:Y235	11.72	No	Yes	0	3	9
271	R:R:V281	R:R:Y235	7.57	Yes	Yes	0	6	9
272	R:R:V237	R:R:Y241	2.52	No	Yes	0	6	8
273	R:R:A238	R:R:P277	3.74	No	Yes	0	6	9
274	R:R:A238	R:R:F280	4.16	No	Yes	0	6	5
275	R:R:A239	R:R:W274	3.89	No	Yes	1	8	9
276	R:R:I313	R:R:Y241	3.63	No	Yes	1	7	8
277	R:R:C317	R:R:Y241	2.69	No	Yes	1	7	8
278	R:R:C361	R:R:Y241	2.69	No	Yes	1	9	8
279	R:R:H363	R:R:Y241	4.36	No	Yes	1	8	8
280	R:R:E364	R:R:Y241	7.86	Yes	Yes	1	8	8
281	R:R:L245	R:R:Y242	2.34	Yes	Yes	1	8	6
282	R:R:I272	R:R:Y242	4.84	Yes	Yes	1	6	6
283	R:R:V276	R:R:Y242	8.83	Yes	Yes	1	3	6
284	R:R:P277	R:R:Y242	6.95	Yes	Yes	1	9	6
285	R:R:F280	R:R:Y242	6.19	Yes	Yes	1	5	6
286	R:R:A316	R:R:Y242	6.67	No	Yes	0	7	6
287	R:R:V246	R:R:W243	3.68	No	Yes	1	8	9
288	R:R:F266	R:R:W243	2	Yes	Yes	1	6	9
289	R:R:V270	R:R:W243	6.13	No	Yes	1	5	9
290	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
291	R:R:W243	R:R:W274	21.56	Yes	Yes	1	9	9
292	R:R:L244	R:R:N320	10.98	No	No	0	9	9
293	R:R:L245	R:R:V249	2.98	Yes	No	0	8	6
294	R:R:I272	R:R:L245	2.85	Yes	Yes	1	6	8
295	R:R:L245	R:R:V319	2.98	Yes	No	0	8	6
296	R:R:L245	R:R:N320	9.61	Yes	No	0	8	9
297	R:R:V246	R:R:Y269	7.57	No	Yes	1	8	7
298	R:R:I272	R:R:V246	6.14	Yes	No	1	6	8
299	R:R:E247	R:R:Y402	16.83	Yes	Yes	1	9	8
300	R:R:G248	R:R:T353	1.82	No	Yes	0	8	9
301	R:R:V249	R:R:Y269	5.05	No	Yes	0	6	7
302	R:R:T253	R:R:Y250	3.75	No	Yes	1	7	8
303	R:R:L254	R:R:Y250	11.72	No	Yes	0	8	8
304	R:R:Y250	R:R:Y269	5.96	Yes	Yes	1	8	7
305	R:R:L349	R:R:Y250	2.34	Yes	Yes	1	9	8
306	R:R:L251	R:R:V327	2.98	Yes	No	0	9	9
307	R:R:L251	R:R:L349	4.15	Yes	Yes	1	9	9
308	R:R:A350	R:R:L251	3.15	No	Yes	0	8	9
309	R:R:L251	R:R:T353	7.37	Yes	Yes	1	9	9
310	R:R:A256	R:R:Y252	5.34	No	No	0	6	8
311	R:R:I323	R:R:Y252	3.63	No	No	0	8	8
312	R:R:T253	R:R:Y269	3.75	No	Yes	1	7	7
313	R:R:F257	R:R:L254	4.87	No	No	0	5	8
314	R:R:I330	R:R:L255	7.14	No	No	0	9	8
315	R:R:L255	R:R:M340	2.83	No	Yes	0	8	5
316	R:R:Q263	R:R:R267	3.5	No	No	0	5	4
317	R:R:I265	R:R:W264	7.05	No	No	0	5	5
318	R:R:L268	R:R:W264	4.56	No	No	0	2	5
319	R:R:I265	R:R:Y269	7.25	No	Yes	0	5	7
320	R:R:F266	R:R:Y269	2.06	Yes	Yes	1	6	7
321	R:R:F266	R:R:V270	6.55	Yes	No	1	6	5
322	R:R:I272	R:R:Y269	2.42	Yes	Yes	1	6	7
323	R:R:V270	R:R:W274	2.45	No	Yes	1	5	9
324	R:R:G273	R:R:I272	5.29	No	Yes	0	9	6
325	R:R:I272	R:R:V276	4.61	Yes	Yes	1	6	3
326	R:R:G275	R:R:P277	2.03	No	Yes	0	6	9
327	R:R:P277	R:R:V276	3.53	Yes	Yes	1	9	3
328	R:R:F280	R:R:V276	2.62	Yes	Yes	1	5	3
329	R:R:F280	R:R:V281	2.62	Yes	Yes	1	5	6
330	R:R:F280	R:R:I308	2.51	Yes	No	0	5	8
331	R:R:F280	R:R:I309	6.28	Yes	Yes	1	5	7
332	R:R:F280	R:R:P312	18.78	Yes	No	0	5	8
333	R:R:F280	R:R:I313	3.77	Yes	No	1	5	7
334	R:R:I309	R:R:V281	3.07	Yes	Yes	1	7	6
335	R:R:P283	R:R:V282	5.3	No	No	0	5	3
336	R:R:I286	R:R:V282	3.07	No	No	0	4	3
337	R:R:I308	R:R:P283	5.08	No	No	0	8	5
338	R:R:G285	R:R:W284	5.63	No	Yes	1	5	8
339	R:R:K288	R:R:W284	19.73	Yes	Yes	1	8	8
340	R:R:W284	R:R:W297	1.87	Yes	Yes	1	8	8
341	R:R:I308	R:R:W284	9.4	No	Yes	0	8	8
342	R:R:I309	R:R:W284	11.74	Yes	Yes	1	7	8
343	R:R:G285	R:R:W297	4.22	No	Yes	1	5	8
344	R:R:I286	R:R:L290	2.85	No	No	0	4	3
345	R:R:K288	R:R:V287	4.55	Yes	No	1	8	4
346	R:R:V287	R:R:Y291	5.05	No	No	0	4	3
347	R:R:V287	R:R:Y305	6.31	No	Yes	1	4	4
348	R:R:E292	R:R:K288	4.05	Yes	Yes	1	6	8
349	R:R:K288	R:R:W297	6.96	Yes	Yes	1	8	8
350	R:R:K288	R:R:Y305	7.17	Yes	Yes	1	8	4
351	R:R:D293	R:R:Y289	5.75	No	No	1	7	3
352	R:R:W297	R:R:Y289	3.86	Yes	No	1	8	3
353	R:R:L290	R:R:Y291	3.52	No	No	0	3	3
354	R:R:E292	R:R:Y305	3.37	Yes	Yes	1	6	4
355	R:R:D293	R:R:W297	3.35	No	Yes	1	7	8
356	R:R:E294	R:R:R299	8.14	No	No	0	4	4
357	R:R:C296	R:R:G295	1.96	Yes	No	0	9	4
358	R:R:C296	R:R:T298	3.38	Yes	No	0	9	5
359	R:R:N300	R:R:W306	4.52	No	No	0	6	6
360	R:R:M303	R:R:Y305	4.79	No	Yes	0	5	4
361	R:R:N304	R:R:W306	5.65	No	No	0	3	6
362	R:R:L307	R:R:N304	6.87	No	No	0	7	3
363	R:R:R310	R:R:W306	4	No	No	0	6	6
364	R:R:I309	R:R:I313	2.94	Yes	No	1	7	7
365	R:R:E364	R:R:R310	4.65	Yes	No	0	8	6
366	R:R:I318	R:R:L314	5.71	No	Yes	0	4	4
367	R:R:A368	R:R:L314	6.3	No	Yes	0	6	4
368	R:R:F315	R:R:V319	2.62	No	No	0	4	6
369	R:R:C317	R:R:C361	7.28	No	No	1	7	9
370	R:R:C317	R:R:E364	3.04	No	Yes	1	7	8
371	R:R:I357	R:R:N320	4.25	Yes	No	0	8	9
372	R:R:C361	R:R:F321	4.19	No	No	0	9	6
373	R:R:F321	R:R:T362	2.59	No	No	0	6	7
374	R:R:F321	R:R:V365	6.55	No	No	0	6	6
375	R:R:F324	R:R:I328	5.02	Yes	No	1	9	7
376	R:R:F324	R:R:L354	7.31	Yes	Yes	1	9	8
377	R:R:F324	R:R:I357	6.28	Yes	Yes	1	9	8
378	R:R:F324	R:R:P358	7.22	Yes	No	1	9	9
379	R:R:L354	R:R:V327	5.96	Yes	No	0	8	9
380	R:R:I328	R:R:L354	4.28	No	Yes	1	7	8
381	R:R:I328	W:W:?2	3.85	No	Yes	1	7	0
382	R:R:I330	R:R:V331	3.07	No	Yes	0	9	8
383	R:R:I330	R:R:K334	8.72	No	No	0	9	9
384	R:R:L335	R:R:V331	2.98	No	Yes	1	8	8
385	R:R:M340	R:R:V331	6.09	Yes	Yes	1	5	8
386	R:R:F347	R:R:V331	2.62	Yes	Yes	1	7	8
387	R:R:V331	W:W:?2	5.02	Yes	Yes	1	8	0
388	R:R:V332	W:W:?2	2.01	No	Yes	0	6	0
389	R:R:K334	R:R:L339	8.46	No	No	0	9	7
390	R:R:K334	R:R:M340	5.76	No	Yes	0	9	5
391	R:R:K342	R:R:L335	7.05	No	No	1	5	8
392	R:R:F347	R:R:L335	2.44	Yes	No	1	7	8
393	R:R:F347	R:R:M340	2.49	Yes	Yes	1	7	5
394	R:R:F347	R:R:K342	22.33	Yes	No	1	7	5
395	R:R:K342	W:W:?2	1.9	No	Yes	1	5	0
396	R:R:E408	R:R:I345	4.1	Yes	No	0	9	5
397	R:R:F347	R:R:K351	11.17	Yes	No	1	7	8
398	R:R:F347	W:W:?2	7.39	Yes	Yes	1	7	0
399	R:R:K351	R:R:R348	8.66	No	No	1	8	8
400	R:R:N407	R:R:R348	15.67	Yes	No	1	6	8
401	R:R:R348	W:W:?2	10.65	No	Yes	1	8	0
402	R:R:L349	R:R:T353	2.95	Yes	Yes	1	9	9
403	R:R:L349	R:R:Y402	3.52	Yes	Yes	1	9	8
404	R:R:L349	W:W:?2	2.8	Yes	Yes	1	9	0
405	R:R:K351	W:W:?2	29.49	No	Yes	1	8	0
406	R:R:L401	R:R:S352	4.5	Yes	No	1	8	9
407	R:R:S352	R:R:Y402	10.17	No	Yes	1	9	8
408	R:R:S352	W:W:?2	6.08	No	Yes	1	9	0
409	R:R:I357	R:R:T353	3.04	Yes	Yes	1	8	9
410	R:R:T353	R:R:Y402	7.49	Yes	Yes	1	9	8
411	R:R:L354	W:W:?2	1.87	Yes	Yes	1	8	0
412	R:R:L401	R:R:T355	4.42	Yes	No	1	8	8
413	R:R:T355	W:W:?2	10.94	No	Yes	1	8	0
414	R:R:L356	R:R:V398	5.96	No	Yes	1	9	9
415	R:R:L356	R:R:L401	5.54	No	Yes	1	9	8
416	R:R:L356	R:R:Y402	4.69	No	Yes	1	9	8
417	R:R:I357	R:R:P358	5.08	Yes	No	1	8	9
418	R:R:L359	R:R:L360	4.15	No	No	0	9	9
419	R:R:L359	R:R:M397	5.65	No	No	0	9	5
420	R:R:L360	R:R:Q394	7.99	No	Yes	0	9	9
421	R:R:E364	R:R:H363	14.77	Yes	No	1	8	8
422	R:R:F367	R:R:H363	2.26	Yes	No	1	7	8
423	R:R:F367	R:R:I366	8.79	Yes	No	0	7	6
424	R:R:F367	R:R:M371	2.49	Yes	No	1	7	7
425	R:R:F367	R:R:R380	31	Yes	No	1	7	5
426	R:R:D372	R:R:F369	5.97	No	No	0	5	4
427	R:R:E373	R:R:V370	4.28	No	No	0	4	5
428	R:R:G377	R:R:M371	5.24	No	No	0	4	7
429	R:R:M371	R:R:R380	7.44	No	No	1	7	5
430	R:R:D372	R:R:E373	2.6	No	No	0	5	4
431	R:R:E373	R:R:H374	6.15	No	No	0	4	3
432	R:R:R376	R:R:T378	10.35	No	No	0	5	2
433	R:R:L379	R:R:R376	3.64	Yes	No	0	3	5
434	R:R:I382	R:R:L379	4.28	No	Yes	0	4	3
435	R:R:F381	R:R:L384	4.87	No	No	0	4	5
436	R:R:F381	R:R:F385	22.51	No	No	0	4	6
437	R:R:F385	R:R:I382	2.51	No	No	0	6	4
438	R:R:K383	R:R:T386	10.51	No	No	0	7	4
439	R:R:D387	R:R:K383	4.15	No	No	0	8	7
440	R:R:L384	R:R:L388	2.77	No	No	0	5	7
441	R:R:F390	R:R:T391	3.89	No	No	0	6	6
442	R:R:Q394	R:R:T391	9.92	Yes	No	0	9	6
443	R:R:F393	R:R:S392	3.96	No	No	1	7	9
444	R:R:I400	R:R:L396	5.71	No	No	0	6	7
445	R:R:L401	R:R:M397	5.65	Yes	No	0	8	5
446	R:R:V398	R:R:Y402	2.52	Yes	Yes	1	9	8
447	R:R:F404	R:R:I400	10.05	No	No	0	8	6
448	R:R:I400	R:R:V405	3.07	No	No	0	6	6
449	R:R:L401	R:R:V405	2.98	Yes	No	1	8	6
450	R:R:L401	W:W:?2	3.73	Yes	Yes	1	8	0
451	R:R:V405	W:W:?2	12.06	No	Yes	1	6	0
452	R:R:E408	R:R:N406	7.89	Yes	Yes	1	9	9
453	R:R:N406	R:R:V409	4.43	Yes	Yes	1	9	9
454	R:R:N406	W:W:?2	12.97	Yes	Yes	1	9	0
455	R:R:E408	R:R:N407	2.63	Yes	Yes	1	9	6
456	R:R:N407	W:W:?2	5.56	Yes	Yes	1	6	0
457	R:R:E412	R:R:V409	9.98	Yes	Yes	1	8	9
458	R:R:E412	R:R:F413	3.5	Yes	No	0	8	5
459	R:R:F413	R:R:W417	11.02	No	No	0	5	5
460	R:R:P96	R:R:V95	1.77	No	No	0	3	5
461	R:R:G248	R:R:I323	1.76	No	No	0	8	8
462	R:R:C341	R:R:T343	1.69	No	No	0	4	5
463	R:R:D222	R:R:G295	1.68	No	No	0	6	4
464	R:R:A375	R:R:T378	1.68	No	No	0	4	2
465	R:R:L60	R:R:P77	1.64	No	No	0	1	4
466	R:R:E76	R:R:G78	1.64	No	No	0	1	7
467	R:R:G98	R:R:Q97	1.64	No	No	0	4	4
468	R:R:L311	R:R:P312	1.64	No	No	0	4	8
469	R:R:S333	R:R:V332	1.62	No	No	0	7	6
470	R:R:A346	R:R:I345	1.62	No	No	0	6	5
471	R:R:A199	R:R:K202	1.61	No	No	0	3	4
472	R:R:T35	R:R:V36	1.59	No	No	0	5	2
473	R:R:A92	R:R:L89	1.58	No	Yes	0	5	5
474	R:R:C341	R:R:D344	1.56	No	No	0	4	7
475	R:R:I146	R:R:V150	1.54	No	No	0	4	5
476	R:R:K202	R:R:S206	1.53	No	No	0	4	4
477	R:R:C226	R:R:Q221	1.53	No	No	0	9	4
478	R:R:A106	R:R:E107	1.51	No	No	0	1	5
479	R:R:M204	R:R:T207	1.51	Yes	No	0	3	3
480	R:R:L314	R:R:V365	1.49	Yes	No	0	4	6
481	R:R:L322	R:R:V319	1.49	No	No	0	5	6
482	R:R:L50	R:R:T51	1.47	No	No	0	4	4
483	R:R:D114	R:R:S116	1.47	No	No	0	4	5
484	R:R:L144	R:R:T386	1.47	No	No	0	6	4
485	R:R:I161	R:R:I165	1.47	No	Yes	0	4	8
486	R:R:D222	R:R:S219	1.47	No	No	0	6	5
487	R:R:A199	R:R:F196	1.39	No	No	0	3	5
488	R:R:C329	R:R:R326	1.39	No	No	0	7	8
489	R:R:L141	R:R:L32	1.38	No	No	0	5	4
490	R:R:L201	R:R:L218	1.38	No	No	0	7	3
491	R:R:L379	R:R:Q37	1.33	Yes	No	0	3	4
492	R:R:F169	R:R:S416	1.32	No	No	0	7	5
493	R:R:R299	R:R:S301	1.32	No	No	0	4	3
494	R:R:N407	R:R:Q410	1.32	Yes	No	0	6	7
495	R:R:E292	R:R:N302	1.31	Yes	No	0	6	5
496	R:R:F324	R:R:V325	1.31	Yes	No	0	9	5
497	R:R:E262	R:R:Q263	1.27	No	No	0	6	5
498	R:R:F369	R:R:L314	1.22	No	Yes	0	4	4
499	R:R:D198	R:R:F195	1.19	No	No	0	7	7
500	R:R:K113	R:R:W120	1.16	No	Yes	0	4	5
501	R:R:E292	R:R:R299	1.16	Yes	No	0	6	4
502	R:R:E418	R:R:R414	1.16	No	No	0	4	6
503	R:R:H173	R:R:R170	1.13	No	No	0	7	8
504	R:R:R326	R:R:Y252	1.03	No	No	0	8	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y42	8.524	5	2	6
2	R:R:R43	7.552	5	2	4
3	R:R:R44	7.4975	4	0	3
4	R:R:P56	6.7425	4	4	1
5	R:R:F61	5.3525	4	4	3
6	R:R:R64	6.6925	4	0	4
7	R:R:F66	7.972	5	2	7
8	R:R:D67	4.9375	4	2	9
9	R:R:Y69	6.25	8	2	6
10	R:R:W72	7.39	7	2	9
11	R:R:C85	4.5975	4	2	9
12	R:R:P86	7.405	6	2	8
13	R:R:W87	9.12	4	2	3
14	R:R:Y88	9.654	5	2	5
15	R:R:L89	4.59833	6	2	5
16	R:R:P90	5.482	5	2	4
17	R:R:W91	5.118	5	2	4
18	R:R:Y101	8.92	6	3	5
19	R:R:R102	11.704	5	2	8
20	R:R:F103	4.696	5	3	4
21	R:R:T105	4.6075	4	3	4
22	R:R:W110	8.37	6	2	9
23	R:R:P119	5.22	4	2	6
24	R:R:W120	3.56167	6	3	5
25	R:R:R121	9.90857	7	2	6
26	R:R:L123	11.5025	4	2	5
27	R:R:S135	5.035	4	2	1
28	R:R:P137	5.385	6	2	3
29	R:R:Y145	6.13	4	1	5
30	R:R:Y148	6.735	4	1	7
31	R:R:Y152	8.596	5	1	7
32	R:R:F156	5.5025	4	5	7
33	R:R:I165	3.7975	4	1	8
34	R:R:L166	7.7675	4	1	8
35	R:R:L172	4.062	5	1	9
36	R:R:R176	6.01	7	1	9
37	R:R:N177	8.355	4	1	9
38	R:R:I179	4.978	5	1	8
39	R:R:H180	8.408	5	1	9
40	R:R:L183	3.826	5	1	9
41	R:R:F184	3.49833	6	1	8
42	R:R:F187	8.18667	6	1	8
43	R:R:I188	4.8825	4	5	7
44	R:R:R190	6.05833	6	1	8
45	R:R:M204	5.81	4	0	3
46	R:R:Y235	6.704	5	0	9
47	R:R:Y241	3.95833	6	1	8
48	R:R:Y242	5.97	6	1	6
49	R:R:W243	8.63625	8	1	9
50	R:R:L245	4.152	5	1	8
51	R:R:E247	10.64	4	1	9
52	R:R:Y250	5.96429	7	1	8
53	R:R:L251	4.4125	4	1	9
54	R:R:F266	3.69667	6	1	6
55	R:R:Y269	4.71125	8	1	7
56	R:R:I272	4.35833	6	1	6
57	R:R:W274	7.42571	7	1	9
58	R:R:V276	4.8975	4	1	3
59	R:R:P277	4.084	5	1	9
60	R:R:F280	5.86625	8	1	5
61	R:R:V281	4.06	4	1	6
62	R:R:W284	7.36875	8	1	8
63	R:R:K288	8.492	5	1	8
64	R:R:E292	2.4725	4	1	6
65	R:R:C296	4.2025	4	0	9
66	R:R:W297	3.75667	6	1	8
67	R:R:Y305	5.41	4	1	4
68	R:R:I309	5.63	5	1	7
69	R:R:L314	3.68	4	0	4
70	R:R:F324	5.428	5	1	9
71	R:R:V331	3.956	5	1	8
72	R:R:M340	4.2925	4	1	5
73	R:R:F347	8.07333	6	1	7
74	R:R:L349	4.39429	7	1	9
75	R:R:T353	4.534	5	1	9
76	R:R:L354	4.855	4	1	8
77	R:R:I357	4.6625	4	1	8
78	R:R:E364	7.58	4	1	8
79	R:R:F367	11.135	4	1	7
80	R:R:L379	2.8825	4	0	3
81	R:R:Q394	9.4475	4	1	9
82	R:R:V398	3.864	5	1	9
83	R:R:L401	4.47	6	1	8
84	R:R:Y402	7.20667	9	1	8
85	R:R:N406	7.83	4	1	9
86	R:R:N407	6.295	4	1	6
87	R:R:E408	4.5275	4	1	9
88	R:R:V409	5.115	4	1	9
89	R:R:E412	8.244	5	1	8
90	W:W:?2	7.75467	15	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:H99	R:R:Y101	10.328	10.89	No	Yes	3	4	5
2	R:R:H99	R:R:Q97	11.5577	3.71	No	No	0	4	4
3	R:R:G98	R:R:Q97	11.9603	1.64	No	No	0	4	4
4	R:R:C85	R:R:G98	12.3204	3.92	Yes	No	2	9	4
5	R:R:P86	R:R:Y42	34.1231	11.13	Yes	Yes	2	8	6
6	R:R:W87	R:R:Y42	23.2915	15.43	Yes	Yes	2	3	6
7	R:R:K38	R:R:W87	16.4308	4.64	No	Yes	0	4	3
8	R:R:E34	R:R:K38	15.2044	2.7	No	No	0	4	4
9	R:R:E34	R:R:W33	12.8721	4.36	No	No	0	4	3
10	R:R:L379	R:R:W33	11.7046	2.28	Yes	No	0	3	3
11	R:R:F66	R:R:Y42	24.6855	3.09	Yes	Yes	2	7	6
12	R:R:F66	R:R:R43	29.6721	18.17	Yes	Yes	2	7	4
13	R:R:L50	R:R:R43	25.1172	2.43	No	Yes	0	4	4
14	R:R:L50	R:R:R64	21.9872	3.64	No	Yes	0	4	4
15	R:R:C85	R:R:V100	13.3739	3.42	Yes	No	2	9	7
16	R:R:V100	R:R:W72	13.6293	2.45	No	Yes	2	7	9
17	R:R:R102	R:R:W72	33.7647	21.99	Yes	Yes	2	8	9
18	R:R:P86	R:R:Y69	17.0977	8.34	Yes	Yes	2	8	6
19	R:R:D67	R:R:Y69	52.9825	5.75	Yes	Yes	2	9	6
20	R:R:A70	R:R:P86	17.0987	3.74	No	Yes	2	5	8
21	R:R:P119	R:R:R102	89.4699	10.09	Yes	Yes	2	6	8
22	R:R:L118	R:R:P119	92.2837	4.93	No	Yes	0	4	6
23	R:R:L118	R:R:S219	92.5437	9.01	No	No	0	4	5
24	R:R:D222	R:R:S219	93.1173	1.47	No	No	0	6	5
25	R:R:D222	R:R:G295	98.1168	1.68	No	No	0	6	4
26	R:R:C296	R:R:G295	98.3879	1.96	Yes	No	0	9	4
27	R:R:C296	R:R:F230	100	4.19	Yes	No	0	9	5
28	R:R:F230	R:R:Q234	35.3227	4.68	No	No	1	5	7
29	R:R:I309	R:R:Q234	35.3534	4.12	Yes	No	1	7	7
30	R:R:I309	R:R:I313	15.54	2.94	Yes	No	1	7	7
31	R:R:I313	R:R:Y241	16.509	3.63	No	Yes	1	7	8
32	R:R:V237	R:R:Y241	12.9073	2.52	No	Yes	0	6	8
33	R:R:R190	R:R:V237	12.8044	3.92	Yes	No	0	8	6
34	R:R:F230	R:R:W284	64.9432	5.01	No	Yes	1	5	8
35	R:R:I309	R:R:W284	37.0524	11.74	Yes	Yes	1	7	8
36	R:R:I309	R:R:V281	17.2208	3.07	Yes	Yes	1	7	6
37	R:R:V281	R:R:Y235	26.6699	7.57	Yes	Yes	0	6	9
38	R:R:W274	R:R:Y235	23.7937	7.72	Yes	Yes	0	9	9
39	R:R:W243	R:R:W274	18.566	21.56	Yes	Yes	1	9	9
40	R:R:L183	R:R:W243	16.5502	3.42	Yes	Yes	1	9	9
41	R:R:F280	R:R:I309	39.9373	6.28	Yes	Yes	1	5	7
42	R:R:F280	R:R:Y242	34.4996	6.19	Yes	Yes	1	5	6
43	R:R:I272	R:R:Y242	25.9776	4.84	Yes	Yes	1	6	6
44	R:R:I272	R:R:Y269	49.6983	2.42	Yes	Yes	1	6	7
45	R:R:Y250	R:R:Y269	41.8093	5.96	Yes	Yes	1	8	7
46	R:R:R176	R:R:Y250	16.0948	8.23	Yes	Yes	1	9	8
47	R:R:I308	R:R:W284	20.8131	9.4	No	Yes	0	8	8
48	R:R:F280	R:R:I308	21.543	2.51	Yes	No	0	5	8
49	R:R:F280	R:R:V276	26.6329	2.62	Yes	Yes	1	5	3
50	R:R:I272	R:R:V276	25.8977	4.61	Yes	Yes	1	6	3
51	R:R:L349	R:R:Y250	22.3976	2.34	Yes	Yes	1	9	8
52	R:R:L349	W:W:?2	20.4847	2.8	Yes	Yes	1	9	0
53	R:R:Y42	R:R:Y88	16.8775	8.94	Yes	Yes	2	6	5
54	R:R:D67	R:R:R102	55.4578	3.57	Yes	Yes	2	9	8
55	R:R:A70	R:R:W72	17.478	3.89	No	Yes	2	5	9
56	R:R:Y69	R:R:Y88	25.7466	4.96	Yes	Yes	2	6	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:H180	R:R:R176	3.39	1	Yes	Yes	9	9	2	2
R:R:R176	R:R:Y250	8.23	1	Yes	Yes	9	8	2	2
R:R:L349	R:R:R176	7.29	1	Yes	Yes	9	9	1	2
R:R:N406	R:R:R176	6.03	1	Yes	Yes	9	9	1	2
R:R:E408	R:R:R176	3.49	1	Yes	Yes	9	9	2	2
R:R:H180	R:R:L349	7.71	1	Yes	Yes	9	9	2	1
R:R:H180	R:R:Y402	15.24	1	Yes	Yes	9	8	2	2
R:R:L349	R:R:Y250	2.34	1	Yes	Yes	9	8	1	2
R:R:L251	R:R:V327	2.98	1	Yes	No	9	9	2	2
R:R:L251	R:R:L349	4.15	1	Yes	Yes	9	9	2	1
R:R:L251	R:R:T353	7.37	1	Yes	Yes	9	9	2	2
R:R:F324	R:R:I328	5.02	1	Yes	No	9	7	2	1
R:R:F324	R:R:L354	7.31	1	Yes	Yes	9	8	2	1
R:R:L354	R:R:V327	5.96	1	Yes	No	8	9	1	2
R:R:I328	R:R:L354	4.28	1	No	Yes	7	8	1	1
R:R:I328	W:W:?2	3.85	1	No	Yes	7	0	1	0
R:R:I330	R:R:V331	3.07	0	No	Yes	9	8	2	1
R:R:L335	R:R:V331	2.98	1	No	Yes	8	8	2	1
R:R:M340	R:R:V331	6.09	1	Yes	Yes	5	8	2	1
R:R:F347	R:R:V331	2.62	1	Yes	Yes	7	8	1	1
R:R:V331	W:W:?2	5.02	1	Yes	Yes	8	0	1	0
R:R:V332	W:W:?2	2.01	0	No	Yes	6	0	1	0
R:R:K342	R:R:L335	7.05	1	No	No	5	8	1	2
R:R:F347	R:R:L335	2.44	1	Yes	No	7	8	1	2
R:R:F347	R:R:M340	2.49	1	Yes	Yes	7	5	1	2
R:R:F347	R:R:K342	22.33	1	Yes	No	7	5	1	1
R:R:K342	W:W:?2	1.9	1	No	Yes	5	0	1	0
R:R:F347	R:R:K351	11.17	1	Yes	No	7	8	1	1
R:R:F347	W:W:?2	7.39	1	Yes	Yes	7	0	1	0
R:R:K351	R:R:R348	8.66	1	No	No	8	8	1	1
R:R:N407	R:R:R348	15.67	1	Yes	No	6	8	1	1
R:R:R348	W:W:?2	10.65	1	No	Yes	8	0	1	0
R:R:L349	R:R:T353	2.95	1	Yes	Yes	9	9	1	2
R:R:L349	R:R:Y402	3.52	1	Yes	Yes	9	8	1	2
R:R:L349	W:W:?2	2.8	1	Yes	Yes	9	0	1	0
R:R:K351	W:W:?2	29.49	1	No	Yes	8	0	1	0
R:R:L401	R:R:S352	4.5	1	Yes	No	8	9	1	1
R:R:S352	R:R:Y402	10.17	1	No	Yes	9	8	1	2
R:R:S352	W:W:?2	6.08	1	No	Yes	9	0	1	0
R:R:T353	R:R:Y402	7.49	1	Yes	Yes	9	8	2	2
R:R:L354	W:W:?2	1.87	1	Yes	Yes	8	0	1	0
R:R:L401	R:R:T355	4.42	1	Yes	No	8	8	1	1
R:R:T355	W:W:?2	10.94	1	No	Yes	8	0	1	0
R:R:L356	R:R:L401	5.54	1	No	Yes	9	8	2	1
R:R:L356	R:R:Y402	4.69	1	No	Yes	9	8	2	2
R:R:L401	R:R:M397	5.65	1	Yes	No	8	5	1	2
R:R:I400	R:R:V405	3.07	0	No	No	6	6	2	1
R:R:L401	R:R:V405	2.98	1	Yes	No	8	6	1	1
R:R:L401	W:W:?2	3.73	1	Yes	Yes	8	0	1	0
R:R:V405	W:W:?2	12.06	1	No	Yes	6	0	1	0
R:R:E408	R:R:N406	7.89	1	Yes	Yes	9	9	2	1
R:R:N406	R:R:V409	4.43	1	Yes	Yes	9	9	1	2
R:R:N406	W:W:?2	12.97	1	Yes	Yes	9	0	1	0
R:R:E408	R:R:N407	2.63	1	Yes	Yes	9	6	2	1
R:R:N407	W:W:?2	5.56	1	Yes	Yes	6	0	1	0
R:R:S333	R:R:V332	1.62	0	No	No	7	6	2	1
R:R:N407	R:R:Q410	1.32	1	Yes	No	6	7	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
62.50	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
60.00	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
60.00	Single	6KJV	PF-06372222	6KJV-GLP-1-PF-06372222
60.00	Single	6KK1	PF-06372222	6KK1-GLP-1-PF-06372222
53.33	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
53.33	Single	6KK7	PF-06372222	6KK7-GLP-1-PF-06372222
47.06	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
46.67	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
27.78	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
26.32	Single	7C7Q	BHFF	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
26.09	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
23.53	Single	7EB2	rac-BHFF	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
20.00	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/β1/γ2
19.05	Single	5X7D	Cmpd-15	5X7D-β₂-S-Carazolol-Cmpd-15
13.64	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
13.33	Single	7E14	PubChem 156022738	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
13.04	Single	8JPF	SBI-553	8JPF-NTS₁-Neurotensin-SBI-553
11.76	Single	4PXF	Octyl-Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl-β-D-Glucopyranoside-Arrestin1 Finger Loop
11.76	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
11.54	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
10.34	Single	8ZYT	SBI-553	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
9.52	Single	5T1A	PubChem 12093170	5T1A-CCR2-BMS-681-PubChem 12093170
9.52	Single	8HNN	SCH546738	8HNN-CXCR3-SCH546738
8.82	Single	3VG9	Antibody	3VG9-A_2A-ZM-241385-Antibody
8.70	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
8.70	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
8.33	Single	8JPC	SBI-553; GDP; Mg	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
8.33	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
8.11	Single	3VGA	Antibody	3VGA-A_2A-ZM-241385-Antibody
8.00	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
8.00	Single	8GW8	PCO371	8GW8-PTH1-PCO371-Gs/β1/γ2
7.69	Single	8JPB	SBI-553; GDP; Mg	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.41	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
7.41	Single	8ZYU	SBI-553	8ZYU-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
7.41	Single	8ZYY	SBI-553	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
6.67	Single	7DUR	PubChem 156022738	7DUR-GLP-1-PubChem 156022738-Gs/β1/γ2
6.25	Single	7EVM	PubChem 156022738	7EVM-GLP-1-PubChem 156022738-Gs/β1/γ2
5.56	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
4.35	Single	8XQN	Aristolochic acid A	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.35	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
4.35	Single	9CLW	4-CMTB	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
3.70	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
3.23	Single	8FN0	SBI-553	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2

PDB Summary
PDB	6LN2
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GLP-1
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	PF-06372222
Protein Partners	-
PDB Resolution	3.2
Date	2020-03-18
D.O.I.	doi.org/10.1038/s41467-020-14934-5

Net Summary
I_min	1.82
Number of Linked Nodes	362
Number of Links	504
Number of Hubs	90
Number of Links mediated by Hubs	343
Number of Communities	5
Number of Nodes involved in Communities	149
Number of Links involved in Communities	261

Path Summary
Number Of Nodes in MetaPath	57
Number Of Links MetaPath	56
Number of Shortest Paths	367182
Length Of Smallest Path	3
Average Path Length	21.0062
Length of Longest Path	36
Minimum Path Strength	1.21
Average Path Strength	5.59875
Maximum Path Strength	21.23
Minimum Path Correlation	0.7
Average Path Correlation	0.943622
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	36.9004
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	59.039
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• FnI-like domain • Rubredoxin-like • G protein-coupled receptor-like
SCOP2	Family Identifier	• FnI-like domain • Rubredoxin-like • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


Code	97Y
PDB Residues	W:W:?2
Environment Details	Open EMBL-EBI Page
Code	97Y
Name	N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Synonyms
Identifier
Formula	C26 H28 F3 N5 O3
Molecular Weight	515.527
SMILES
PubChem	68178630
Formal Charge	0
Total Atoms	65
Total Chiral Atoms	1
Total Bonds	68
Total Aromatic Bonds	17


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>6LN2_Chain_R T V S L W E T V Q K W R E Y R R Q C Q R S L T E D P P P A T D L F C N R T F D E Y A C W P D G E P G S F V N V S C P W Y L P W A S S V P Q G H V Y R F C T A E G L W L Q K D N S S L P W R D L S E C E E S S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L C V F F K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L A C R L V F L L C Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F E Q W I F R L Y V A I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A C I V N F L I F V R V I C I V V S K L K A N L M C K T D I A F R L A K S T L T L I P L L C T H E V I F A F V M D E H A R G T L R F I K L F T D L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	doi.org/10.1038/nature22378
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.2	2020-03-18	doi.org/10.1038/s41467-020-14934-5
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.1	2019-11-13	doi.org/10.1107/S2052252519013496
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	doi.org/10.1038/nature22378
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	doi.org/10.1021/acs.jmedchem.1c01856
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	doi.org/10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	doi.org/10.1038/nature22394
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	doi.org/10.1038/nature22800
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	doi.org/10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	doi.org/10.1038/nature25773
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	9EBN	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBN (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-	Gs/β1/γ2	3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-		3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	8YWF	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ2	2.74	2025-04-16	To be published
	8YWF (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.74	2025-04-16	To be published
	9BYO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-	Gs/β1/γ2	2.31	2025-06-11	To be published
	9BYO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-		2.31	2025-06-11	To be published
	9C0K	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	2.72	2025-06-11	To be published
	9C0K (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		2.72	2025-06-11	To be published

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