psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D11	A:A:Q12	3.92	No	No	0	2	2
2	A:A:D11	A:A:N14	8.08	No	No	0	2	3
3	A:A:Q12	A:A:R13	16.35	No	No	0	2	4
4	A:A:E16	A:A:R13	6.98	Yes	No	0	4	4
5	A:A:K17	A:A:R13	8.66	No	No	0	4	4
6	A:A:E16	A:A:Q19	5.1	Yes	Yes	2	4	4
7	A:A:E16	A:A:R20	10.47	Yes	No	0	4	3
8	A:A:E16	B:B:T86	7.06	Yes	Yes	2	4	6
9	A:A:Q19	B:B:D83	6.53	Yes	Yes	2	4	8
10	A:A:Q19	B:B:T86	11.34	Yes	Yes	2	4	6
11	A:A:Q19	B:B:N88	15.85	Yes	No	2	4	7
12	A:A:E27	A:A:N23	9.2	No	No	2	6	7
13	A:A:N23	B:B:N88	12.26	No	No	2	7	7
14	A:A:N23	B:B:K89	5.6	No	Yes	2	7	9
15	A:A:I26	B:B:K89	4.36	No	Yes	0	9	9
16	A:A:E27	B:B:K89	6.75	No	Yes	2	6	9
17	A:A:K28	A:A:Q29	5.42	No	No	0	4	4
18	A:A:K32	A:A:Q29	9.49	No	No	0	4	4
19	A:A:D33	A:A:Q29	5.22	No	No	0	5	4
20	A:A:L30	B:B:K78	4.23	No	Yes	0	5	8
21	A:A:K34	A:A:Q31	12.2	Yes	No	0	4	4
22	A:A:D33	B:B:K78	4.15	No	Yes	0	5	8
23	A:A:K34	A:A:Q35	4.07	Yes	Yes	0	4	3
24	A:A:K34	A:A:R38	3.71	Yes	Yes	2	4	4
25	A:A:K34	B:B:L55	8.46	Yes	Yes	2	4	6
26	A:A:Q35	R:R:S261	4.33	Yes	No	0	3	7
27	A:A:Q35	R:R:E262	11.47	Yes	No	0	3	6
28	A:A:Q35	R:R:Q263	3.84	Yes	No	0	3	5
29	A:A:R38	A:A:Y37	9.26	Yes	Yes	2	4	4
30	A:A:R42	A:A:Y37	18.52	No	Yes	0	9	4
31	A:A:Y37	B:B:L55	7.03	Yes	Yes	2	4	6
32	A:A:R38	B:B:L55	4.86	Yes	Yes	2	4	6
33	A:A:R38	R:R:E262	4.65	Yes	No	0	4	6
34	A:A:H220	A:A:T40	4.11	Yes	No	0	7	7
35	A:A:F219	A:A:H41	6.79	Yes	No	0	8	6
36	A:A:H41	A:A:T242	8.21	No	No	0	6	8
37	A:A:H41	A:A:I383	5.3	No	No	0	6	8
38	A:A:I245	A:A:L43	5.71	No	No	0	7	7
39	A:A:F238	A:A:L44	19.49	Yes	No	0	9	9
40	A:A:I244	A:A:L44	4.28	No	No	0	8	9
41	A:A:L45	A:A:M221	9.9	No	No	0	8	8
42	A:A:D223	A:A:L45	6.79	No	No	0	9	8
43	A:A:F246	A:A:L46	4.87	Yes	No	0	9	8
44	A:A:G206	A:A:S205	3.71	No	No	1	8	7
45	A:A:S205	B:B:N119	4.47	No	Yes	1	7	9
46	A:A:G206	B:B:N119	5.09	No	Yes	1	8	9
47	A:A:F222	A:A:I207	5.02	Yes	No	1	7	9
48	A:A:I207	B:B:W99	3.52	No	Yes	1	9	9
49	A:A:F208	A:A:G225	4.52	No	No	0	5	9
50	A:A:E209	A:A:K211	14.85	No	No	1	9	4
51	A:A:E209	A:A:H220	9.85	No	Yes	1	9	7
52	A:A:E209	A:A:F222	5.83	No	Yes	1	9	7
53	A:A:M221	A:A:T210	6.02	No	No	0	8	7
54	A:A:H220	A:A:K211	10.48	Yes	No	1	7	4
55	A:A:F212	A:A:F219	11.79	No	Yes	0	9	8
56	A:A:F212	A:A:M221	4.98	No	No	0	9	8
57	A:A:F212	A:A:I372	3.77	No	No	0	9	8
58	A:A:K216	A:A:Q213	13.56	No	No	0	4	3
59	A:A:N218	A:A:Q213	15.85	No	No	0	4	3
60	A:A:R373	A:A:V214	6.54	Yes	No	15	5	6
61	A:A:F376	A:A:V214	13.11	Yes	No	15	8	6
62	A:A:D215	A:A:R373	11.91	No	Yes	15	5	5
63	A:A:D215	A:A:F376	8.36	No	Yes	15	5	8
64	A:A:F219	A:A:V217	3.93	Yes	No	0	8	5
65	A:A:F219	A:A:F376	8.57	Yes	Yes	0	8	8
66	A:A:C379	A:A:F219	5.59	No	Yes	0	8	8
67	A:A:F222	A:A:H220	6.79	Yes	Yes	1	7	7
68	A:A:F222	B:B:W99	19.04	Yes	Yes	1	7	9
69	A:A:V224	A:A:W234	9.81	No	Yes	0	9	9
70	A:A:Q227	A:A:W234	5.48	Yes	Yes	1	9	9
71	A:A:Q227	B:B:L117	6.65	Yes	Yes	1	9	9
72	A:A:Q227	B:B:N119	3.96	Yes	Yes	1	9	9
73	A:A:Q227	B:B:G144	4.93	Yes	No	1	9	8
74	A:A:Q227	B:B:Y145	6.76	Yes	Yes	1	9	8
75	A:A:E230	A:A:R228	8.14	No	No	0	9	9
76	A:A:R228	B:B:T164	5.17	No	No	0	9	6
77	A:A:R228	B:B:D186	4.76	No	No	0	9	9
78	A:A:E230	A:A:R232	5.82	No	No	0	9	8
79	A:A:R231	A:A:W234	11	No	Yes	0	9	9
80	A:A:R232	B:B:C204	5.57	No	Yes	1	8	7
81	A:A:R232	B:B:D228	14.29	No	Yes	1	8	9
82	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
83	A:A:K233	B:B:M188	10.08	Yes	No	1	9	8
84	A:A:K233	B:B:C204	4.85	Yes	Yes	1	9	7
85	A:A:K233	B:B:D228	8.3	Yes	Yes	1	9	9
86	A:A:K233	B:B:N230	4.2	Yes	No	1	9	9
87	A:A:K233	B:B:D246	5.53	Yes	Yes	1	9	9
88	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
89	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
90	A:A:W234	B:B:L117	4.56	Yes	Yes	1	9	9
91	A:A:W234	B:B:Y145	4.82	Yes	Yes	1	9	8
92	A:A:I235	A:A:L282	4.28	No	No	0	9	9
93	A:A:Q236	A:A:W281	5.48	No	Yes	1	8	5
94	A:A:Q236	B:B:R314	7.01	No	Yes	1	8	8
95	A:A:C237	A:A:F238	4.19	No	Yes	0	8	9
96	A:A:C237	B:B:Y59	5.38	No	Yes	1	8	8
97	A:A:C237	B:B:M101	4.86	No	Yes	1	8	9
98	A:A:F238	A:A:V241	3.93	Yes	No	0	9	9
99	A:A:F238	B:B:W99	13.03	Yes	Yes	0	9	9
100	A:A:D240	A:A:N239	4.04	No	No	1	6	8
101	A:A:N239	B:B:K57	6.99	No	Yes	1	8	9
102	A:A:N239	B:B:W332	7.91	No	Yes	1	8	9
103	A:A:D240	B:B:K57	11.06	No	Yes	1	6	9
104	A:A:D240	B:B:W99	4.47	No	Yes	1	6	9
105	A:A:I244	A:A:T285	4.56	No	No	0	8	7
106	A:A:F246	A:A:V248	5.24	Yes	No	0	9	7
107	A:A:F246	A:A:L272	6.09	Yes	No	0	9	8
108	A:A:F246	A:A:F273	7.5	Yes	Yes	0	9	9
109	A:A:N292	A:A:V247	4.43	Yes	No	0	9	7
110	A:A:L291	A:A:V248	4.47	No	No	0	8	7
111	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
112	A:A:N264	A:A:Y311	9.3	No	No	0	9	6
113	A:A:K293	A:A:R265	3.71	No	No	0	9	9
114	A:A:I341	A:A:L266	8.56	No	No	0	8	8
115	A:A:E344	A:A:L270	5.3	Yes	No	0	5	6
116	A:A:F345	A:A:L270	8.53	Yes	No	0	8	6
117	A:A:I276	A:A:L272	4.28	No	No	0	8	8
118	A:A:F273	A:A:W277	8.02	Yes	Yes	7	9	6
119	A:A:F273	A:A:V287	5.24	Yes	No	7	9	6
120	A:A:F273	A:A:L289	4.87	Yes	No	7	9	9
121	A:A:F273	A:A:F345	8.57	Yes	Yes	7	9	8
122	A:A:F273	A:A:I348	7.54	Yes	No	7	9	4
123	A:A:F273	A:A:S349	3.96	Yes	No	7	9	7
124	A:A:C359	A:A:F273	4.19	No	Yes	7	5	9
125	A:A:D274	A:A:N278	4.04	No	No	0	5	8
126	A:A:D274	A:A:I348	8.4	No	No	0	5	4
127	A:A:V287	A:A:W277	4.9	No	Yes	7	6	6
128	A:A:I348	A:A:W277	3.52	No	Yes	7	4	6
129	A:A:S349	A:A:W277	11.12	No	Yes	7	7	6
130	A:A:H357	A:A:W277	25.39	No	Yes	0	7	6
131	A:A:N279	A:A:W281	4.52	No	Yes	0	8	5
132	A:A:L282	A:A:N279	12.36	No	No	0	9	8
133	A:A:K280	A:A:W281	9.28	No	Yes	1	5	5
134	A:A:K280	B:B:D290	4.15	No	Yes	1	5	6
135	A:A:W281	B:B:D290	7.82	Yes	Yes	1	5	6
136	A:A:W281	B:B:R314	16.99	Yes	Yes	1	5	8
137	A:A:W281	B:B:W332	8.43	Yes	Yes	1	5	9
138	A:A:R283	A:A:R356	13.86	No	Yes	0	3	2
139	A:A:D284	A:A:R356	5.96	No	Yes	0	4	2
140	A:A:I382	A:A:S286	9.29	No	No	0	6	8
141	A:A:F290	A:A:I288	3.77	Yes	Yes	0	9	9
142	A:A:D378	A:A:I288	9.8	No	Yes	0	7	9
143	A:A:L289	A:A:L291	4.15	No	No	0	9	8
144	A:A:F345	A:A:L289	9.74	Yes	No	7	8	9
145	A:A:F290	A:A:H362	7.92	Yes	No	16	9	9
146	A:A:F290	A:A:T364	5.19	Yes	Yes	16	9	9
147	A:A:F290	A:A:N371	7.25	Yes	No	16	9	9
148	A:A:F290	A:A:R374	6.41	Yes	Yes	16	9	4
149	A:A:F363	A:A:L291	3.65	Yes	No	0	5	8
150	A:A:N292	A:A:T364	4.39	Yes	Yes	0	9	9
151	A:A:E309	A:A:I308	4.1	No	No	0	4	7
152	A:A:I308	A:A:Y311	4.84	No	No	0	7	6
153	A:A:D310	A:A:E309	3.9	No	No	0	3	4
154	A:A:F312	A:A:F340	7.5	Yes	Yes	23	8	7
155	A:A:E344	A:A:F312	3.5	Yes	Yes	23	5	8
156	A:A:E314	A:A:F340	4.66	No	Yes	0	6	7
157	A:A:F315	A:A:R336	16.03	No	No	0	6	5
158	A:A:F315	A:A:F340	19.29	No	Yes	0	6	7
159	A:A:P321	A:A:Y318	4.17	No	No	0	5	6
160	A:A:F340	A:A:Y318	9.28	Yes	No	0	7	6
161	A:A:D343	A:A:Y318	5.75	No	No	0	3	6
162	A:A:P321	A:A:T320	5.25	No	No	0	5	1
163	A:A:T320	A:A:Y339	3.75	No	Yes	0	1	3
164	A:A:D323	A:A:E322	9.09	No	No	0	4	1
165	A:A:A324	A:A:Y339	5.34	No	Yes	0	3	3
166	A:A:P326	A:A:T325	5.25	No	No	0	1	2
167	A:A:E330	A:A:P326	6.29	Yes	No	0	3	1
168	A:A:P326	A:A:T335	8.74	No	No	0	1	4
169	A:A:D331	A:A:P332	4.83	No	No	0	4	1
170	A:A:D331	A:A:R333	8.34	No	No	0	4	5
171	A:A:D331	A:A:V334	7.3	No	No	0	4	4
172	A:A:K338	A:A:T335	6.01	No	No	0	5	4
173	A:A:K338	A:A:Y339	3.58	No	Yes	13	5	3
174	A:A:F363	A:A:K338	16.13	Yes	No	13	5	5
175	A:A:F363	A:A:Y339	8.25	Yes	Yes	13	5	3
176	A:A:E344	A:A:F340	16.32	Yes	Yes	23	5	7
177	A:A:L346	A:A:R342	4.86	No	No	13	4	4
178	A:A:P361	A:A:R342	12.97	No	No	13	5	4
179	A:A:F363	A:A:R342	12.83	Yes	No	13	5	4
180	A:A:E344	A:A:R347	11.63	Yes	No	0	5	4
181	A:A:L346	A:A:P361	6.57	No	No	13	4	5
182	A:A:C359	A:A:S349	5.16	No	No	7	5	7
183	A:A:D354	A:A:R356	10.72	No	Yes	0	3	2
184	A:A:G355	A:A:Y358	4.35	No	Yes	0	2	4
185	A:A:H357	A:A:R356	12.41	No	Yes	0	7	2
186	A:A:Y358	A:A:Y360	4.96	Yes	Yes	0	4	8
187	A:A:R385	A:A:Y358	14.4	Yes	Yes	0	5	4
188	A:A:R389	A:A:Y358	6.17	No	Yes	0	4	4
189	A:A:D378	A:A:Y360	14.94	No	Yes	0	7	8
190	A:A:D381	A:A:Y360	10.34	No	Yes	0	8	8
191	A:A:I382	A:A:Y360	7.25	No	Yes	0	6	8
192	A:A:H362	A:A:R374	5.64	No	Yes	16	9	4
193	A:A:D378	A:A:H362	10.08	No	No	0	7	9
194	A:A:N371	A:A:T364	5.85	No	Yes	16	9	9
195	A:A:R374	A:A:T364	3.88	Yes	Yes	16	4	9
196	A:A:N371	A:A:R374	8.44	No	Yes	16	9	4
197	A:A:F376	A:A:R373	5.34	Yes	Yes	15	8	5
198	A:A:N377	A:A:R373	7.23	No	Yes	15	4	5
199	A:A:F376	A:A:N377	3.62	Yes	No	15	8	4
200	A:A:N377	A:A:R380	10.85	No	No	0	4	7
201	A:A:Q384	A:A:R380	3.5	No	No	0	6	7
202	A:A:D381	A:A:R385	15.48	No	Yes	19	8	5
203	A:A:D381	R:R:K334	11.06	No	Yes	19	8	9
204	A:A:H387	A:A:I383	3.98	Yes	No	0	8	8
205	A:A:Q384	R:R:L255	3.99	No	Yes	0	6	8
206	A:A:Q384	R:R:K334	8.14	No	Yes	0	6	9
207	A:A:L394	A:A:R385	3.64	No	Yes	19	8	5
208	A:A:R385	R:R:K334	12.38	Yes	Yes	19	5	9
209	A:A:H387	A:A:M386	5.25	Yes	No	3	8	3
210	A:A:M386	A:A:R389	3.72	No	No	0	3	4
211	A:A:M386	A:A:Q390	5.44	No	No	3	3	4
212	A:A:H387	A:A:Q390	6.18	Yes	No	3	8	4
213	A:A:H387	R:R:L254	18	Yes	No	0	8	8
214	A:A:L388	A:A:L393	4.15	No	No	0	8	8
215	A:A:L388	A:A:L394	8.3	No	No	0	8	8
216	A:A:L388	R:R:L255	4.15	No	Yes	0	8	8
217	A:A:Q390	R:R:R176	3.5	No	Yes	3	4	9
218	A:A:Y391	R:R:R176	6.17	Yes	Yes	3	4	9
219	A:A:Y391	R:R:H180	4.36	Yes	Yes	3	4	9
220	A:A:Y391	R:R:E247	4.49	Yes	Yes	3	4	9
221	A:A:Y391	R:R:Y250	4.96	Yes	Yes	3	4	8
222	A:A:Y391	R:R:L251	9.38	Yes	No	0	4	9
223	A:A:Y391	R:R:Y402	5.96	Yes	Yes	3	4	8
224	A:A:E392	R:R:N407	13.15	No	No	0	6	6
225	A:A:L394	R:R:K334	5.64	No	Yes	19	8	9
226	B:B:E3	B:B:Q6	10.19	No	No	0	5	1
227	B:B:L4	B:B:R8	8.5	No	No	0	4	3
228	B:B:D5	B:B:R8	7.15	No	No	0	1	3
229	B:B:L7	B:B:Q6	9.32	No	No	0	8	1
230	B:B:Q13	B:B:Q9	7.68	No	No	0	1	3
231	B:B:E10	B:B:Q13	14.02	Yes	No	0	8	1
232	B:B:E10	B:B:L14	3.98	Yes	No	0	8	8
233	B:B:L14	B:B:Q17	6.65	No	Yes	0	8	4
234	B:B:L14	G:G:L19	5.54	No	No	0	8	9
235	B:B:K15	B:B:R19	8.66	No	No	0	6	4
236	B:B:N16	B:B:R19	4.82	No	No	0	1	4
237	B:B:I18	B:B:Q17	4.12	Yes	Yes	0	7	4
238	B:B:Q17	G:G:A23	4.55	Yes	No	0	4	8
239	B:B:I18	B:B:R22	3.76	Yes	No	0	7	6
240	B:B:I18	G:G:E22	6.83	Yes	Yes	0	7	9
241	B:B:I18	G:G:R27	5.01	Yes	Yes	0	7	8
242	B:B:D258	B:B:R22	11.91	Yes	No	0	7	6
243	B:B:Q259	B:B:R22	5.84	No	No	0	6	6
244	B:B:D27	G:G:K29	16.59	No	No	0	8	4
245	B:B:D27	G:G:S31	8.83	No	No	0	8	9
246	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
247	B:B:L261	B:B:L30	4.15	No	No	0	5	5
248	B:B:L30	B:B:M262	9.9	No	Yes	0	5	4
249	B:B:L300	B:B:T34	4.42	No	No	0	6	5
250	B:B:N35	B:B:N36	9.54	No	No	0	1	1
251	B:B:I37	B:B:R283	3.76	No	Yes	0	2	9
252	B:B:I37	G:G:M38	4.37	No	No	0	2	4
253	B:B:K301	B:B:P39	5.02	No	No	0	5	1
254	B:B:G41	B:B:V40	3.68	No	Yes	0	1	3
255	B:B:R283	B:B:V40	6.54	Yes	Yes	8	9	3
256	B:B:D298	B:B:V40	7.3	Yes	Yes	8	9	3
257	B:B:V40	G:G:L51	4.47	Yes	Yes	8	3	6
258	B:B:Q44	B:B:R42	9.35	No	No	0	4	2
259	B:B:G306	B:B:R42	6	No	No	0	4	2
260	B:B:R42	R:R:L422	3.64	No	No	0	2	4
261	B:B:I43	B:B:L284	4.28	No	Yes	0	3	5
262	B:B:L308	B:B:M45	7.07	No	No	0	7	4
263	B:B:M45	G:G:L50	7.07	No	No	0	4	9
264	B:B:R46	B:B:R48	5.33	No	Yes	0	5	7
265	B:B:K337	B:B:T47	7.51	Yes	No	14	6	3
266	B:B:T47	B:B:W339	9.7	No	Yes	14	3	9
267	B:B:N340	B:B:R48	10.85	No	Yes	2	9	7
268	B:B:R48	G:G:N59	3.62	Yes	Yes	2	7	9
269	B:B:R48	G:G:R62	7.46	Yes	No	2	7	7
270	B:B:I338	B:B:R49	5.01	No	No	2	5	7
271	B:B:R49	G:G:F61	10.69	No	Yes	2	7	8
272	B:B:R52	B:B:T50	9.06	No	No	0	7	3
273	B:B:K337	B:B:T50	10.51	Yes	No	0	6	3
274	B:B:L51	B:B:W82	18.22	Yes	Yes	0	9	9
275	B:B:L336	B:B:L51	6.92	No	Yes	0	7	9
276	B:B:I338	B:B:L51	4.28	No	Yes	0	5	9
277	B:B:F335	B:B:R52	9.62	No	No	0	4	7
278	B:B:R52	R:R:R170	19.19	No	No	0	7	8
279	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
280	B:B:H54	B:B:S72	9.76	Yes	No	0	9	9
281	B:B:H54	B:B:S74	12.55	Yes	No	2	9	9
282	B:B:D76	B:B:H54	3.78	Yes	Yes	2	9	9
283	B:B:H54	B:B:I80	13.26	Yes	Yes	2	9	8
284	B:B:D76	B:B:L55	10.86	Yes	Yes	2	9	6
285	B:B:K57	B:B:Y59	5.97	Yes	Yes	1	9	8
286	B:B:K57	B:B:Q75	13.56	Yes	No	1	9	9
287	B:B:K57	B:B:W332	16.24	Yes	Yes	1	9	9
288	B:B:Q75	B:B:Y59	10.15	No	Yes	1	9	8
289	B:B:M101	B:B:Y59	7.18	Yes	Yes	1	9	8
290	B:B:W332	B:B:Y59	12.54	Yes	Yes	1	9	8
291	B:B:M61	B:B:W63	4.65	No	Yes	0	6	7
292	B:B:C317	B:B:M61	6.48	No	No	0	7	6
293	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
294	B:B:H62	B:B:R150	16.93	No	No	0	6	6
295	B:B:L70	B:B:W63	5.69	No	Yes	0	5	7
296	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
297	B:B:T321	B:B:W63	10.92	No	Yes	0	7	7
298	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
299	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
300	B:B:D322	B:B:T65	4.34	No	No	0	1	1
301	B:B:D66	B:B:R68	5.96	No	Yes	0	8	5
302	B:B:D66	B:B:L69	6.79	No	No	0	8	5
303	B:B:S67	B:B:T321	7.99	No	No	24	5	7
304	B:B:D323	B:B:S67	8.83	No	No	24	7	5
305	B:B:D83	B:B:R68	15.48	Yes	Yes	2	8	5
306	B:B:R68	B:B:Y85	25.72	Yes	No	2	5	4
307	B:B:R68	B:B:T86	3.88	Yes	Yes	2	5	6
308	B:B:D83	B:B:L69	4.07	Yes	No	0	8	5
309	B:B:L69	B:B:Y105	5.86	No	Yes	0	5	6
310	B:B:L70	B:B:W82	4.56	No	Yes	0	5	9
311	B:B:I81	B:B:V71	4.61	No	Yes	0	7	8
312	B:B:V71	B:B:Y105	3.79	Yes	Yes	6	8	6
313	B:B:V112	B:B:V71	4.81	Yes	Yes	6	8	8
314	B:B:S72	B:B:W82	7.41	No	Yes	0	9	9
315	B:B:L336	B:B:S72	7.51	No	No	0	7	9
316	B:B:A73	B:B:C103	3.61	No	No	0	9	8
317	B:B:D76	B:B:S74	8.83	Yes	No	2	9	9
318	B:B:Q75	B:B:W99	6.57	No	Yes	1	9	9
319	B:B:D76	B:B:K78	8.3	Yes	Yes	0	9	8
320	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
321	B:B:K78	B:B:P94	6.69	Yes	No	0	8	5
322	B:B:I93	B:B:L79	8.56	No	No	0	7	7
323	B:B:L79	B:B:L95	6.92	No	Yes	6	7	8
324	B:B:C114	B:B:L79	6.35	Yes	No	6	8	7
325	B:B:I80	B:B:W82	15.27	Yes	Yes	2	8	9
326	B:B:I80	B:B:K89	5.82	Yes	Yes	2	8	9
327	B:B:H91	B:B:I81	9.28	No	No	0	5	7
328	B:B:K89	B:B:W82	10.44	Yes	Yes	2	9	9
329	B:B:D83	B:B:T86	8.67	Yes	Yes	2	8	6
330	B:B:S84	G:G:F61	5.28	No	Yes	0	5	8
331	B:B:Y85	G:G:P60	12.52	No	No	2	4	9
332	B:B:Y85	G:G:F61	7.22	No	Yes	2	4	8
333	B:B:N88	B:B:T86	8.77	No	Yes	2	7	6
334	B:B:H91	B:B:V90	8.3	No	No	0	5	5
335	B:B:H91	B:B:V133	4.15	No	No	0	5	4
336	B:B:I93	B:B:Y124	7.25	No	Yes	0	7	6
337	B:B:I93	B:B:V133	6.14	No	No	0	7	4
338	B:B:L95	B:B:V100	4.47	Yes	No	6	8	9
339	B:B:C114	B:B:L95	4.76	Yes	Yes	6	8	8
340	B:B:L95	B:B:Y124	7.03	Yes	Yes	6	8	6
341	B:B:D118	B:B:S97	11.78	No	No	0	9	8
342	B:B:S98	B:B:W99	3.71	No	Yes	0	8	9
343	B:B:L117	B:B:W99	4.56	Yes	Yes	1	9	9
344	B:B:C114	B:B:V100	5.12	Yes	No	6	8	9
345	B:B:G116	B:B:M101	5.24	No	Yes	0	9	9
346	B:B:M101	B:B:Y145	8.38	Yes	Yes	1	9	8
347	B:B:C149	B:B:T102	5.07	No	No	0	8	8
348	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
349	B:B:V112	B:B:Y105	3.79	Yes	Yes	6	8	6
350	B:B:L126	B:B:Y105	3.52	No	Yes	6	5	6
351	B:B:A106	B:B:F151	4.16	No	Yes	0	6	9
352	B:B:N110	B:B:S108	7.45	Yes	No	12	4	6
353	B:B:D154	B:B:S108	8.83	No	No	12	6	6
354	B:B:N110	B:B:Y111	4.65	Yes	Yes	12	4	4
355	B:B:K127	B:B:N110	6.99	No	Yes	0	4	4
356	B:B:D154	B:B:N110	6.73	No	Yes	12	6	4
357	B:B:I123	B:B:Y111	3.63	Yes	Yes	12	6	4
358	B:B:N125	B:B:Y111	10.47	No	Yes	0	4	4
359	B:B:S136	B:B:Y111	5.09	No	Yes	0	4	4
360	B:B:D154	B:B:Y111	9.2	No	Yes	12	6	4
361	B:B:V112	B:B:Y124	3.79	Yes	Yes	6	8	6
362	B:B:L126	B:B:V112	5.96	No	Yes	6	5	8
363	B:B:C114	B:B:Y124	4.03	Yes	Yes	6	8	6
364	B:B:L117	B:B:Y145	3.52	Yes	Yes	1	9	8
365	B:B:D118	B:B:I120	7	No	No	0	9	6
366	B:B:G144	B:B:N119	5.09	No	Yes	1	8	9
367	B:B:C121	B:B:L139	6.35	No	No	0	8	9
368	B:B:C121	B:B:C149	3.64	No	No	0	8	8
369	B:B:S122	B:B:Y124	5.09	No	Yes	0	8	6
370	B:B:I123	B:B:L139	4.28	Yes	No	0	6	9
371	B:B:F151	B:B:I123	5.02	Yes	Yes	0	9	6
372	B:B:I123	B:B:I171	8.83	Yes	No	12	6	6
373	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
374	B:B:N125	B:B:T128	4.39	No	No	0	4	3
375	B:B:K127	B:B:L126	4.23	No	No	0	4	5
376	B:B:E130	B:B:T128	11.29	No	No	0	3	3
377	B:B:E130	B:B:R134	13.96	No	No	0	3	3
378	B:B:N132	B:B:R134	6.03	No	No	0	3	3
379	B:B:E138	B:B:V135	7.13	No	No	0	6	4
380	B:B:G174	B:B:R137	6	No	No	0	4	5
381	B:B:L139	B:B:W169	15.94	No	Yes	0	9	8
382	B:B:G141	B:B:W169	4.22	No	Yes	0	5	8
383	B:B:H142	B:B:L146	3.86	Yes	No	9	9	7
384	B:B:H142	B:B:T159	6.85	Yes	No	9	9	9
385	B:B:H142	B:B:S161	16.74	Yes	No	9	9	9
386	B:B:D163	B:B:H142	6.3	Yes	Yes	9	9	9
387	B:B:H142	B:B:W169	7.41	Yes	Yes	9	9	8
388	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
389	B:B:G162	B:B:Y145	5.79	No	Yes	0	9	8
390	B:B:D186	B:B:Y145	10.34	No	Yes	0	9	8
391	B:B:M188	B:B:Y145	4.79	No	Yes	1	8	8
392	B:B:L146	B:B:T159	8.84	No	No	9	7	9
393	B:B:S147	B:B:S160	4.89	No	No	0	9	6
394	B:B:C148	B:B:R150	5.57	No	No	0	6	6
395	B:B:C148	B:B:L190	4.76	No	Yes	0	6	5
396	B:B:F151	B:B:I157	3.77	Yes	No	0	9	7
397	B:B:L152	B:B:Q156	9.32	No	No	0	3	5
398	B:B:L152	B:B:L192	4.15	No	No	0	3	5
399	B:B:L152	B:B:T196	4.42	No	No	0	3	1
400	B:B:D153	B:B:N155	4.04	No	No	0	5	3
401	B:B:D153	B:B:Q156	5.22	No	No	0	5	5
402	B:B:D170	B:B:N155	9.42	Yes	No	20	9	3
403	B:B:E172	B:B:N155	6.57	No	No	20	6	3
404	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
405	B:B:I157	B:B:I171	4.42	No	No	0	7	6
406	B:B:L190	B:B:V158	4.47	Yes	No	10	5	5
407	B:B:F199	B:B:V158	5.24	Yes	No	10	9	5
408	B:B:T159	B:B:W169	10.92	No	Yes	9	9	8
409	B:B:S160	B:B:V187	6.46	No	No	0	6	9
410	B:B:L190	B:B:S160	4.5	Yes	No	0	5	6
411	B:B:G162	B:B:S161	3.71	No	No	0	9	9
412	B:B:D163	B:B:S161	7.36	Yes	No	9	9	9
413	B:B:D163	B:B:T165	11.56	Yes	No	0	9	7
414	B:B:C166	B:B:F180	4.19	No	Yes	10	8	7
415	B:B:C166	B:B:V187	5.12	No	No	0	8	9
416	B:B:C166	B:B:F199	4.19	No	Yes	10	8	9
417	B:B:A167	B:B:W169	5.19	No	Yes	9	4	8
418	B:B:A167	B:B:Q176	4.55	No	No	9	4	4
419	B:B:L168	B:B:T178	5.9	No	No	0	6	4
420	B:B:Q176	B:B:W169	14.24	No	Yes	9	4	8
421	B:B:D170	B:B:E172	7.8	Yes	No	20	9	6
422	B:B:D170	B:B:T173	7.23	Yes	No	20	9	5
423	B:B:D170	B:B:T177	4.34	Yes	No	0	9	4
424	B:B:E172	B:B:T173	8.47	No	No	20	6	5
425	B:B:Q175	B:B:T173	5.67	No	No	0	4	5
426	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
427	B:B:F180	B:B:F199	12.86	Yes	Yes	10	7	9
428	B:B:F180	B:B:W211	13.03	Yes	Yes	10	7	8
429	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
430	B:B:H183	B:B:V187	9.69	Yes	No	0	9	9
431	B:B:H183	B:B:S201	5.58	Yes	No	0	9	9
432	B:B:A203	B:B:H183	8.78	No	Yes	0	8	9
433	B:B:D205	B:B:H183	5.04	No	Yes	0	9	9
434	B:B:H183	B:B:K209	18.34	Yes	Yes	0	9	6
435	B:B:D205	B:B:T184	5.78	No	No	0	9	3
436	B:B:C204	B:B:D186	7.78	Yes	No	0	7	9
437	B:B:F199	B:B:L190	7.31	Yes	Yes	10	9	5
438	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
439	B:B:F199	B:B:L192	3.65	Yes	No	0	9	5
440	B:B:A193	B:B:D195	4.63	No	No	0	4	5
441	B:B:A193	B:B:F234	4.16	No	Yes	0	4	5
442	B:B:G238	B:B:P194	4.06	No	No	0	7	4
443	B:B:D195	B:B:R197	8.34	No	No	0	5	5
444	B:B:R197	B:B:R214	9.6	No	No	0	5	9
445	B:B:L198	B:B:L210	6.92	No	Yes	4	3	5
446	B:B:L198	B:B:R219	3.64	No	No	4	3	5
447	B:B:F199	B:B:W211	14.03	Yes	Yes	10	9	8
448	B:B:I232	B:B:V200	7.68	Yes	No	4	8	6
449	B:B:F234	B:B:V200	10.49	Yes	No	0	5	6
450	B:B:F241	B:B:V200	15.73	Yes	No	4	6	6
451	B:B:S201	B:B:W211	7.41	No	Yes	0	9	8
452	B:B:G202	B:B:I229	5.29	No	No	0	6	7
453	B:B:C204	B:B:D228	10.89	Yes	Yes	1	7	9
454	B:B:D205	B:B:S207	5.89	No	No	0	9	5
455	B:B:K209	B:B:S207	4.59	Yes	No	0	6	5
456	B:B:K209	B:B:W211	8.12	Yes	Yes	10	6	8
457	B:B:C218	B:B:K209	4.85	No	Yes	10	5	6
458	B:B:K209	B:B:T221	12.01	Yes	No	0	6	7
459	B:B:L210	B:B:R219	6.07	Yes	No	4	5	5
460	B:B:L210	B:B:Q220	7.99	Yes	Yes	4	5	7
461	B:B:L210	B:B:L255	4.15	Yes	No	0	5	6
462	B:B:C218	B:B:W211	5.22	No	Yes	10	5	8
463	B:B:D212	B:B:E215	12.99	No	No	0	9	3
464	B:B:E215	B:B:R214	4.65	No	No	0	3	9
465	B:B:E215	B:B:M217	8.12	No	No	0	3	3
466	B:B:C218	G:G:Q18	9.16	No	No	0	5	9
467	B:B:Q220	B:B:R219	7.01	Yes	No	4	7	5
468	B:B:F222	B:B:Q220	7.03	Yes	Yes	4	8	7
469	B:B:D258	B:B:Q220	10.44	Yes	Yes	4	7	7
470	B:B:Q220	G:G:I25	4.12	Yes	No	0	7	2
471	B:B:T221	G:G:E22	8.47	No	Yes	0	7	9
472	B:B:F222	B:B:F241	11.79	Yes	Yes	4	8	6
473	B:B:F222	B:B:F253	9.65	Yes	Yes	4	8	6
474	B:B:D258	B:B:F222	3.58	Yes	Yes	4	7	8
475	B:B:H225	B:B:I229	7.95	Yes	No	4	9	7
476	B:B:H225	B:B:T243	12.32	Yes	Yes	4	9	8
477	B:B:H225	B:B:S245	13.95	Yes	No	4	9	9
478	B:B:D247	B:B:H225	5.04	Yes	Yes	4	9	9
479	B:B:H225	B:B:R251	20.31	Yes	Yes	4	9	8
480	B:B:F253	B:B:H225	4.53	Yes	Yes	4	6	9
481	B:B:D247	B:B:E226	10.39	Yes	No	0	9	3
482	B:B:D228	B:B:S227	5.89	Yes	No	0	9	6
483	B:B:D246	B:B:S227	4.42	Yes	No	0	9	6
484	B:B:I229	B:B:T243	4.56	No	Yes	4	7	8
485	B:B:D246	B:B:N230	9.42	Yes	No	1	9	9
486	B:B:F241	B:B:I232	5.02	Yes	Yes	4	6	8
487	B:B:I232	B:B:T243	4.56	Yes	Yes	4	8	8
488	B:B:F234	B:B:L255	4.87	Yes	No	0	5	6
489	B:B:F235	B:B:P236	8.67	Yes	Yes	17	6	7
490	B:B:F235	B:B:F278	7.5	Yes	Yes	17	6	7
491	B:B:F235	B:B:G282	4.52	Yes	No	17	6	9
492	B:B:F235	G:G:L37	4.87	Yes	No	0	6	7
493	B:B:F235	G:G:Y40	6.19	Yes	Yes	17	6	6
494	B:B:F278	B:B:P236	5.78	Yes	Yes	17	7	7
495	B:B:G282	B:B:P236	4.06	No	Yes	17	9	7
496	B:B:P236	G:G:Y40	5.56	Yes	Yes	17	7	6
497	B:B:N237	B:B:N239	8.17	No	No	0	5	2
498	B:B:N237	G:G:Y40	12.79	No	Yes	0	5	6
499	B:B:N239	B:B:R256	15.67	No	No	0	2	9
500	B:B:F241	B:B:F253	11.79	Yes	Yes	4	6	6
501	B:B:G244	B:B:T243	3.64	No	Yes	0	5	8
502	B:B:F253	B:B:T243	9.08	Yes	Yes	4	6	8
503	B:B:G244	B:B:I273	7.05	No	No	0	5	6
504	B:B:D247	B:B:S245	8.83	Yes	No	4	9	9
505	B:B:D247	B:B:T249	13.01	Yes	Yes	4	9	6
506	B:B:D247	B:B:R251	4.76	Yes	Yes	4	9	8
507	B:B:R251	B:B:T249	10.35	Yes	Yes	4	8	6
508	B:B:T249	B:B:T263	4.71	Yes	No	4	6	1
509	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
510	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
511	B:B:C250	B:B:I273	6.55	No	No	0	8	6
512	B:B:F253	B:B:R251	4.28	Yes	Yes	4	6	8
513	B:B:E260	B:B:R251	11.63	No	Yes	4	6	8
514	B:B:R251	B:B:T263	11.64	Yes	No	4	8	1
515	B:B:L252	B:B:L261	4.15	No	No	0	7	5
516	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
517	B:B:E260	B:B:F253	7	No	Yes	4	6	6
518	B:B:A257	B:B:D254	4.63	No	No	0	7	9
519	B:B:D254	B:B:L261	12.21	No	No	0	9	5
520	B:B:D254	G:G:A33	4.63	No	No	0	9	7
521	B:B:R256	G:G:I28	7.52	No	No	0	9	4
522	B:B:R256	G:G:D36	7.15	No	No	0	9	5
523	B:B:A257	B:B:Q259	4.55	No	No	0	7	6
524	B:B:D258	G:G:R27	9.53	Yes	Yes	0	7	8
525	B:B:Q259	G:G:V30	5.73	No	No	0	6	8
526	B:B:M262	B:B:Y264	13.17	Yes	Yes	0	4	5
527	B:B:A302	B:B:M262	4.83	No	Yes	0	2	4
528	B:B:L285	B:B:Y264	4.69	Yes	Yes	0	6	5
529	B:B:W297	B:B:Y264	11.58	Yes	Yes	0	8	5
530	B:B:H266	B:B:N268	8.93	No	No	0	4	4
531	B:B:H266	B:B:I269	3.98	No	Yes	11	4	4
532	B:B:H266	B:B:R304	9.03	No	Yes	11	4	5
533	B:B:I269	B:B:Y289	6.04	Yes	Yes	11	4	7
534	B:B:I269	B:B:N295	4.25	Yes	Yes	11	4	6
535	B:B:I269	B:B:R304	3.76	Yes	Yes	11	4	5
536	B:B:C271	B:B:Y289	4.03	No	Yes	0	5	7
537	B:B:C271	B:B:D291	6.22	No	No	0	5	8
538	B:B:I273	B:B:Y289	10.88	No	Yes	0	6	7
539	B:B:D290	B:B:T274	7.23	Yes	No	1	6	8
540	B:B:R314	B:B:T274	5.17	Yes	No	1	8	8
541	B:B:L318	B:B:S275	6.01	No	No	0	6	8
542	B:B:F278	B:B:G282	4.52	Yes	No	17	7	9
543	B:B:F278	B:B:L285	6.09	Yes	Yes	0	7	6
544	B:B:L284	B:B:S279	4.5	Yes	No	0	5	9
545	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
546	B:B:G324	B:B:K280	5.23	No	No	0	9	1
547	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
548	B:B:D298	B:B:R283	15.48	Yes	Yes	8	9	9
549	B:B:L300	B:B:R283	10.93	No	Yes	8	6	9
550	B:B:R283	G:G:C41	5.57	Yes	No	8	9	7
551	B:B:R283	G:G:L51	4.86	Yes	Yes	8	9	6
552	B:B:L284	B:B:V296	5.96	Yes	No	0	5	5
553	B:B:L284	G:G:L51	4.15	Yes	Yes	0	5	6
554	B:B:L286	B:B:V296	4.47	No	No	0	7	5
555	B:B:L286	B:B:V327	4.47	No	No	0	7	6
556	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
557	B:B:C294	B:B:G288	3.92	No	No	0	5	7
558	B:B:N295	B:B:Y289	11.63	Yes	Yes	11	6	7
559	B:B:W297	B:B:Y289	5.79	Yes	Yes	11	8	7
560	B:B:D290	B:B:R314	11.91	Yes	Yes	1	6	8
561	B:B:D291	B:B:N293	12.12	No	Yes	0	8	5
562	B:B:F292	B:B:N313	3.62	No	No	0	4	7
563	B:B:N293	B:B:N295	5.45	Yes	Yes	11	5	6
564	B:B:N293	B:B:V307	4.43	Yes	No	11	5	3
565	B:B:C294	B:B:V315	5.12	No	No	0	5	7
566	B:B:N295	B:B:W297	4.52	Yes	Yes	11	6	8
567	B:B:N295	B:B:R304	15.67	Yes	Yes	11	6	5
568	B:B:N295	B:B:V307	4.43	Yes	No	11	6	3
569	B:B:R304	B:B:W297	4	Yes	Yes	11	5	8
570	B:B:D298	B:B:K301	11.06	Yes	No	8	9	5
571	B:B:D298	B:B:D303	3.99	Yes	No	8	9	2
572	B:B:L300	G:G:C41	6.35	No	No	8	6	7
573	B:B:D303	B:B:K301	5.53	No	No	8	2	5
574	B:B:L308	B:B:W339	20.5	No	Yes	0	7	9
575	B:B:G310	R:R:R419	4.5	No	No	0	5	7
576	B:B:H311	B:B:V315	4.15	Yes	No	0	9	7
577	B:B:H311	B:B:T329	6.85	Yes	No	0	9	8
578	B:B:H311	B:B:S331	16.74	Yes	No	14	9	9
579	B:B:D333	B:B:H311	5.04	Yes	Yes	14	9	9
580	B:B:H311	B:B:K337	14.41	Yes	Yes	14	9	6
581	B:B:D312	B:B:D333	6.65	No	Yes	0	5	9
582	B:B:D312	R:R:H171	18.91	No	No	0	5	7
583	B:B:D312	R:R:K415	8.3	No	No	0	5	7
584	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
585	B:B:D333	B:B:N313	4.04	Yes	No	0	9	7
586	B:B:R314	B:B:W332	23.99	Yes	Yes	1	8	9
587	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
588	B:B:L318	B:B:T329	4.42	No	No	0	6	8
589	B:B:V320	B:B:V327	6.41	No	No	0	7	6
590	B:B:D323	B:B:T321	7.23	No	No	24	7	7
591	B:B:D323	B:B:M325	8.32	No	No	0	7	5
592	B:B:M325	G:G:P49	5.03	No	No	0	5	7
593	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
594	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
595	B:B:G330	B:B:L336	5.13	No	No	0	5	7
596	B:B:D333	B:B:S331	8.83	Yes	No	14	9	9
597	B:B:D333	B:B:F335	8.36	Yes	No	0	9	4
598	B:B:F335	B:B:S334	3.96	No	No	0	4	4
599	B:B:K337	B:B:W339	8.12	Yes	Yes	14	6	9
600	B:B:I338	G:G:F61	6.28	No	Yes	2	5	8
601	B:B:N340	G:G:N59	13.62	No	Yes	2	9	9
602	B:B:N340	G:G:F61	4.83	No	Yes	2	9	8
603	G:G:I9	G:G:T6	6.08	No	No	0	2	3
604	G:G:I9	G:G:R13	6.26	No	No	0	2	6
605	G:G:E17	G:G:K14	4.05	No	No	0	6	4
606	G:G:K20	G:G:V16	4.55	No	No	0	6	7
607	G:G:E22	G:G:Q18	5.1	Yes	No	0	9	9
608	G:G:E22	G:G:L19	3.98	Yes	No	0	9	9
609	G:G:M21	G:G:N24	4.21	No	No	0	1	1
610	G:G:I25	G:G:R27	7.52	No	Yes	0	2	8
611	G:G:H44	G:G:Y40	25.04	No	Yes	0	6	6
612	G:G:E47	G:G:H44	6.15	No	No	0	3	6
613	G:G:D48	G:G:L51	9.5	Yes	Yes	0	9	6
614	G:G:P55	G:G:V54	3.53	No	No	2	5	6
615	G:G:E58	G:G:V54	4.28	No	No	2	5	6
616	G:G:N59	G:G:V54	7.39	Yes	No	2	9	6
617	G:G:E58	G:G:P55	14.15	No	No	2	5	5
618	G:G:A56	G:G:R62	5.53	No	No	0	4	7
619	G:G:E58	G:G:S57	7.19	No	No	0	5	6
620	G:G:N59	G:G:P60	6.52	Yes	No	2	9	9
621	G:G:N59	G:G:R62	8.44	Yes	No	2	9	7
622	G:G:F61	G:G:P60	7.22	Yes	No	2	8	9
623	R:R:E139	R:R:P137	4.72	No	No	0	2	3
624	R:R:E138	R:R:L141	7.95	No	No	0	2	5
625	R:R:E138	R:R:L142	5.3	No	No	0	2	3
626	R:R:E139	R:R:Q140	5.1	No	No	0	2	4
627	R:R:F143	R:R:I146	7.54	No	No	0	4	4
628	R:R:F143	R:R:I147	3.77	No	No	0	4	6
629	R:R:L144	R:R:L384	4.15	No	No	0	6	5
630	R:R:F385	R:R:L144	3.65	No	No	0	6	6
631	R:R:L144	R:R:L388	8.3	No	No	0	6	7
632	R:R:T149	R:R:Y145	8.74	No	Yes	5	7	5
633	R:R:D198	R:R:Y145	10.34	No	Yes	5	7	5
634	R:R:L201	R:R:Y145	7.03	Yes	Yes	5	7	5
635	R:R:K202	R:R:Y145	4.78	Yes	Yes	5	4	5
636	R:R:Y145	W:W:?1	10.1	Yes	Yes	5	5	0
637	R:R:Y148	R:R:Y152	15.89	Yes	Yes	5	7	7
638	R:R:V194	R:R:Y148	8.83	No	Yes	5	7	7
639	R:R:S392	R:R:Y148	7.63	No	Yes	5	9	7
640	R:R:Y148	W:W:?1	4.42	Yes	Yes	5	7	0
641	R:R:D198	R:R:T149	7.23	No	No	5	7	7
642	R:R:F393	R:R:G151	9.03	No	No	0	7	8
643	R:R:R190	R:R:Y152	4.12	Yes	Yes	0	8	7
644	R:R:A191	R:R:Y152	5.34	No	Yes	0	7	7
645	R:R:V194	R:R:Y152	16.4	No	Yes	5	7	7
646	R:R:S392	R:R:Y152	10.17	No	Yes	5	9	7
647	R:R:G395	R:R:S155	3.71	No	No	0	9	9
648	R:R:F156	R:R:I188	7.54	Yes	No	0	7	7
649	R:R:A191	R:R:F156	4.16	No	Yes	0	7	7
650	R:R:F156	R:R:L192	3.65	Yes	No	0	7	3
651	R:R:F156	R:R:F195	10.72	Yes	No	0	7	7
652	R:R:F184	R:R:L159	4.87	No	Yes	0	8	9
653	R:R:F187	R:R:L159	6.09	Yes	Yes	3	8	9
654	R:R:I188	R:R:L159	4.28	No	Yes	0	7	9
655	R:R:G395	R:R:L159	5.13	No	Yes	3	9	9
656	R:R:F404	R:R:I161	3.77	Yes	No	0	8	4
657	R:R:A162	R:R:C403	3.61	No	No	0	9	9
658	R:R:F184	R:R:S163	3.96	No	No	0	8	6
659	R:R:F169	R:R:I165	3.77	Yes	No	18	7	8
660	R:R:C403	R:R:I165	4.91	No	No	0	9	8
661	R:R:F413	R:R:I165	7.54	No	No	18	5	8
662	R:R:L166	R:R:N177	6.87	No	Yes	0	8	9
663	R:R:L166	R:R:L181	4.15	No	No	0	8	6
664	R:R:L167	R:R:L181	4.15	No	No	0	3	6
665	R:R:F169	R:R:L172	7.31	Yes	Yes	18	7	9
666	R:R:E412	R:R:F169	8.16	Yes	Yes	18	8	7
667	R:R:F169	R:R:F413	9.65	Yes	No	18	7	5
668	R:R:E412	R:R:H171	12.31	Yes	No	0	8	7
669	R:R:E408	R:R:L172	3.98	No	Yes	0	9	9
670	R:R:L172	R:R:V409	5.96	Yes	No	0	9	9
671	R:R:E412	R:R:L172	11.93	Yes	Yes	18	8	9
672	R:R:H173	R:R:Y178	11.98	No	No	0	7	6
673	R:R:C174	R:R:N177	6.3	No	Yes	0	8	9
674	R:R:T175	R:R:Y250	4.99	No	Yes	0	7	8
675	R:R:F266	R:R:T175	3.89	Yes	No	0	6	7
676	R:R:N177	R:R:R176	6.03	Yes	Yes	3	9	9
677	R:R:H180	R:R:R176	5.64	Yes	Yes	3	9	9
678	R:R:R176	R:R:Y250	4.12	Yes	Yes	3	9	8
679	R:R:H180	R:R:N177	3.83	Yes	Yes	3	9	9
680	R:R:F266	R:R:Y178	8.25	Yes	No	0	6	6
681	R:R:I179	R:R:W243	4.7	No	Yes	0	8	9
682	R:R:E247	R:R:I179	10.93	Yes	No	0	9	8
683	R:R:E247	R:R:H180	11.08	Yes	Yes	3	9	9
684	R:R:H180	R:R:Y402	7.62	Yes	Yes	3	9	8
685	R:R:N182	R:R:W243	12.43	No	Yes	3	9	9
686	R:R:N182	R:R:W274	5.65	No	Yes	3	9	9
687	R:R:F187	R:R:L183	4.87	Yes	No	3	8	9
688	R:R:L183	R:R:L244	4.15	No	No	3	9	9
689	R:R:E247	R:R:L183	5.3	Yes	No	3	9	9
690	R:R:F184	R:R:V398	3.93	No	No	0	8	9
691	R:R:N240	R:R:S186	5.96	Yes	No	3	9	9
692	R:R:S186	R:R:W243	6.18	No	Yes	3	9	9
693	R:R:S186	R:R:W274	6.18	No	Yes	3	9	9
694	R:R:F187	R:R:N240	18.12	Yes	Yes	3	8	9
695	R:R:F187	R:R:L244	4.87	Yes	No	3	8	9
696	R:R:F187	R:R:Q394	11.71	Yes	No	0	8	9
697	R:R:F187	R:R:G395	7.53	Yes	No	3	8	9
698	R:R:F187	R:R:V398	7.87	Yes	No	0	8	9
699	R:R:C236	R:R:L189	6.35	No	No	0	5	7
700	R:R:R190	R:R:V237	10.46	Yes	No	0	8	6
701	R:R:N240	R:R:R190	9.64	Yes	Yes	0	9	8
702	R:R:R190	R:R:Y241	12.35	Yes	Yes	0	8	8
703	R:R:M233	R:R:S193	6.13	No	No	0	6	6
704	R:R:V194	W:W:?1	4.01	No	Yes	5	7	0
705	R:R:K197	R:R:M233	7.2	No	No	0	6	6
706	R:R:K197	W:W:?1	25.07	No	Yes	0	6	0
707	R:R:D198	R:R:K202	8.3	No	Yes	5	7	4
708	R:R:A200	W:W:?1	10.18	No	Yes	0	4	0
709	R:R:K202	R:R:L201	7.05	Yes	Yes	5	4	7
710	R:R:L201	R:R:M204	4.24	Yes	No	5	7	3
711	R:R:L201	R:R:Y205	14.07	Yes	No	5	7	3
712	R:R:L201	W:W:?1	10.44	Yes	Yes	5	7	0
713	R:R:K202	R:R:Y205	4.78	Yes	No	5	4	3
714	R:R:M204	R:R:W203	4.65	No	Yes	5	3	3
715	R:R:T207	R:R:W203	12.13	No	Yes	0	3	3
716	R:R:A208	R:R:W203	3.89	No	Yes	0	4	3
717	R:R:W203	W:W:?1	13.5	Yes	Yes	5	3	0
718	R:R:M204	W:W:?1	12.95	No	Yes	5	3	0
719	R:R:S206	R:R:T207	4.8	No	No	0	4	3
720	R:R:Q211	R:R:Q213	10.24	No	No	0	4	4
721	R:R:H212	R:R:W214	5.29	No	No	0	3	1
722	R:R:L217	W:W:?1	6.71	No	Yes	0	4	0
723	R:R:S225	R:R:Y220	7.63	No	Yes	0	3	3
724	R:R:C226	R:R:Y220	9.41	No	Yes	5	9	3
725	R:R:V229	R:R:Y220	6.31	No	Yes	0	7	3
726	R:R:W297	R:R:Y220	4.82	Yes	Yes	5	8	3
727	R:R:Y220	W:W:?1	9.47	Yes	Yes	5	3	0
728	R:R:Q221	R:R:W297	15.33	No	Yes	0	4	8
729	R:R:D222	R:R:R227	5.96	No	No	0	6	8
730	R:R:S223	R:R:S225	6.52	No	No	0	4	3
731	R:R:C226	R:R:C296	7.28	No	No	5	9	9
732	R:R:C226	R:R:W297	5.22	No	Yes	5	9	8
733	R:R:C296	R:R:R227	5.57	No	No	0	9	8
734	R:R:F230	R:R:Q234	14.05	No	No	0	5	7
735	R:R:F230	R:R:W284	5.01	No	Yes	0	5	8
736	R:R:F230	W:W:?1	7.22	No	Yes	0	5	0
737	R:R:A239	R:R:Y235	5.34	No	No	0	8	9
738	R:R:W274	R:R:Y235	7.72	Yes	No	0	9	9
739	R:R:L278	R:R:Y235	5.86	No	No	0	3	9
740	R:R:A239	R:R:P277	3.74	No	No	0	8	9
741	R:R:L244	R:R:N240	5.49	No	Yes	3	9	9
742	R:R:I313	R:R:Y241	8.46	No	Yes	0	7	8
743	R:R:I317	R:R:Y241	4.84	No	Yes	0	7	8
744	R:R:E364	R:R:Y241	10.1	No	Yes	0	8	8
745	R:R:L245	R:R:Y242	4.69	No	Yes	0	8	6
746	R:R:V276	R:R:Y242	3.79	No	Yes	25	3	6
747	R:R:P277	R:R:Y242	8.34	No	Yes	25	9	6
748	R:R:F280	R:R:Y242	9.28	No	Yes	0	5	6
749	R:R:A316	R:R:Y242	6.67	No	Yes	0	7	6
750	R:R:V246	R:R:W243	6.13	No	Yes	0	8	9
751	R:R:V270	R:R:W243	4.9	No	Yes	0	5	9
752	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
753	R:R:W243	R:R:W274	25.3	Yes	Yes	3	9	9
754	R:R:L245	R:R:N320	9.61	No	No	0	8	9
755	R:R:V246	R:R:Y269	5.05	No	Yes	0	8	7
756	R:R:E247	R:R:L359	7.95	Yes	No	0	9	9
757	R:R:G248	R:R:I323	3.53	No	No	0	8	8
758	R:R:V249	R:R:Y269	5.05	No	Yes	0	6	7
759	R:R:L254	R:R:Y250	12.89	No	Yes	0	8	8
760	R:R:Y250	R:R:Y269	4.96	Yes	Yes	0	8	7
761	R:R:L251	R:R:L255	4.15	No	Yes	0	9	8
762	R:R:L251	R:R:V327	4.47	No	No	0	9	9
763	R:R:A256	R:R:Y252	8.01	No	No	0	6	8
764	R:R:F257	R:R:Y252	6.19	No	No	0	5	8
765	R:R:R326	R:R:Y252	9.26	No	No	0	8	8
766	R:R:F257	R:R:T253	5.19	No	No	0	5	7
767	R:R:T253	R:R:Y269	3.75	No	Yes	0	7	7
768	R:R:I330	R:R:L255	4.28	No	Yes	0	9	8
769	R:R:E262	R:R:F260	3.5	No	No	0	6	7
770	R:R:F260	R:R:I265	3.77	No	No	0	7	5
771	R:R:I265	R:R:W264	3.52	No	No	0	5	5
772	R:R:I265	R:R:Y269	4.84	No	Yes	0	5	7
773	R:R:F266	R:R:R267	8.55	Yes	No	0	6	4
774	R:R:F266	R:R:V270	5.24	Yes	No	0	6	5
775	R:R:I272	R:R:L268	5.71	No	No	0	6	2
776	R:R:I272	R:R:V276	6.14	No	No	0	6	3
777	R:R:P277	R:R:V276	3.53	No	No	25	9	3
778	R:R:F280	R:R:P312	15.89	No	No	0	5	8
779	R:R:W284	R:R:W306	8.43	Yes	Yes	0	8	6
780	R:R:I308	R:R:W284	8.22	No	Yes	0	8	8
781	R:R:I309	R:R:W284	15.27	No	Yes	0	7	8
782	R:R:L290	R:R:Y291	4.69	No	No	0	3	3
783	R:R:E292	R:R:N300	17.09	No	No	0	6	6
784	R:R:E292	R:R:Y305	11.22	No	No	0	6	4
785	R:R:E294	R:R:G295	4.91	No	No	0	4	4
786	R:R:E294	R:R:T298	4.23	No	No	0	4	5
787	R:R:C296	R:R:W297	6.53	No	Yes	5	9	8
788	R:R:W297	W:W:?1	26.38	Yes	Yes	5	8	0
789	R:R:M303	R:R:R299	3.72	No	No	21	5	4
790	R:R:R299	R:R:W306	10	No	Yes	21	4	6
791	R:R:R299	R:R:R310	4.26	No	Yes	21	4	6
792	R:R:M303	R:R:R310	4.96	No	Yes	21	5	6
793	R:R:W306	R:R:Y305	8.68	Yes	No	0	6	4
794	R:R:R310	R:R:W306	12	Yes	Yes	21	6	6
795	R:R:F315	R:R:V319	5.24	No	No	0	4	6
796	R:R:L360	R:R:N320	8.24	No	No	0	9	9
797	R:R:F321	R:R:V325	5.24	No	No	0	6	5
798	R:R:F321	R:R:V365	7.87	No	No	0	6	6
799	R:R:F324	R:R:I328	3.77	No	No	0	9	7
800	R:R:F324	R:R:L356	7.31	No	No	0	9	9
801	R:R:F324	R:R:T362	16.86	No	No	0	9	7
802	R:R:L356	R:R:V327	4.47	No	No	0	9	9
803	R:R:I328	R:R:T353	4.56	No	No	0	7	9
804	R:R:L349	R:R:V332	4.47	No	No	0	9	6
805	R:R:I345	R:R:L335	9.99	No	No	0	5	8
806	R:R:K351	R:R:R348	9.9	No	No	0	8	8
807	R:R:T355	R:R:Y402	3.75	No	Yes	0	8	8
808	R:R:M397	R:R:P358	6.71	No	No	0	5	9
809	R:R:L359	R:R:L360	4.15	No	No	0	9	9
810	R:R:L359	R:R:Y402	22.27	No	Yes	0	9	8
811	R:R:E364	R:R:H363	11.08	No	Yes	0	8	8
812	R:R:H363	R:R:Q394	13.6	Yes	No	0	8	9
813	R:R:F367	R:R:T386	7.78	Yes	No	0	7	4
814	R:R:E387	R:R:F367	5.83	No	Yes	0	8	7
815	R:R:F367	R:R:F390	7.5	Yes	No	0	7	6
816	R:R:M371	R:R:V370	4.56	No	No	0	7	5
817	R:R:E373	R:R:H374	3.69	Yes	No	22	4	3
818	R:R:E373	R:R:T378	7.06	Yes	No	22	4	2
819	R:R:E373	R:R:L379	3.98	Yes	No	22	4	3
820	R:R:E373	R:R:R380	4.65	Yes	Yes	0	4	5
821	R:R:H374	R:R:T378	8.21	No	No	22	3	2
822	R:R:A375	R:R:R376	4.15	No	No	0	4	5
823	R:R:G377	R:R:R380	6	No	Yes	0	4	5
824	R:R:L379	R:R:T378	4.42	No	No	22	3	2
825	R:R:K383	R:R:R380	4.95	No	Yes	0	7	5
826	R:R:L384	R:R:R380	9.72	No	Yes	0	5	5
827	R:R:F381	R:R:I382	3.77	No	No	0	4	4
828	R:R:E387	R:R:K383	5.4	No	No	0	8	7
829	R:R:F385	R:R:S389	3.96	No	No	0	6	5
830	R:R:F390	R:R:S389	3.96	No	No	0	6	5
831	R:R:F390	R:R:M397	4.98	No	No	0	6	5
832	R:R:F393	R:R:L396	4.87	No	No	0	7	7
833	R:R:I400	R:R:L396	4.28	No	No	0	6	7
834	R:R:F404	R:R:I400	3.77	Yes	No	0	8	6
835	R:R:C403	R:R:F404	6.98	No	Yes	0	9	8
836	R:R:E408	R:R:N406	11.83	No	No	0	9	9
837	R:R:N406	R:R:V409	8.87	No	No	0	9	9
838	R:R:E412	R:R:K415	8.1	Yes	No	0	8	7
839	R:R:E418	R:R:R414	12.79	No	No	0	4	6
840	R:R:K415	R:R:R419	8.66	No	No	0	7	7
841	R:R:E418	R:R:W417	11.99	No	No	0	4	5
842	R:R:W417	R:R:W420	3.75	No	No	26	5	4
843	R:R:R421	R:R:W417	13	No	No	26	4	5
844	R:R:R421	R:R:W420	6	No	No	26	4	4
845	B:B:E12	B:B:R8	3.49	No	No	0	4	3
846	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
847	B:B:G319	B:B:M61	3.49	No	No	0	5	6
848	B:B:C233	B:B:S277	3.44	No	No	0	3	5
849	R:R:C236	R:R:S193	3.44	No	No	0	5	6
850	B:B:C103	B:B:V71	3.42	No	Yes	0	8	8
851	B:B:G115	B:B:L146	3.42	No	No	0	9	7
852	R:R:G285	R:R:L231	3.42	No	No	0	5	5
853	B:B:A11	G:G:V16	3.39	No	No	0	5	7
854	R:R:I357	R:R:P358	3.39	No	No	0	8	9
855	R:R:F367	R:R:H363	3.39	Yes	Yes	0	7	8
856	R:R:G295	R:R:Q221	3.29	No	No	0	4	4
857	R:R:L401	R:R:P358	3.28	No	No	0	8	9
858	B:B:E260	B:B:G224	3.27	No	No	0	6	6
859	A:A:I26	B:B:A92	3.25	No	No	0	9	6
860	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
861	B:B:A28	B:B:I33	3.25	No	No	0	4	3
862	B:B:I33	G:G:A34	3.25	No	No	0	3	6
863	B:B:A305	B:B:I43	3.25	No	No	0	4	3
864	B:B:A92	B:B:I80	3.25	No	Yes	0	6	8
865	B:B:A140	B:B:I120	3.25	No	No	0	5	6
866	R:R:A238	R:R:I313	3.25	No	No	0	6	7
867	R:R:S352	R:R:V331	3.23	No	No	0	9	8
868	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
869	A:A:A22	A:A:K25	3.21	No	No	0	4	5
870	B:B:S207	B:B:T223	3.2	No	No	0	5	2
871	R:R:G361	R:R:H363	3.18	No	Yes	0	9	8
872	B:B:L30	G:G:A34	3.15	No	No	0	5	6
873	B:B:A240	G:G:L37	3.15	No	No	0	6	7
874	B:B:A242	B:B:L285	3.15	No	Yes	0	4	6
875	A:A:E330	A:A:P328	3.14	Yes	No	0	3	1
876	B:B:T165	B:B:T179	3.14	No	No	0	7	4
877	B:B:T165	B:B:T181	3.14	No	No	0	7	2
878	B:B:A309	B:B:N293	3.13	No	Yes	0	3	5
879	A:A:S205	B:B:I120	3.1	No	No	0	7	6
880	B:B:I232	B:B:S189	3.1	Yes	No	0	8	7
881	G:G:I9	G:G:S8	3.1	No	No	0	2	4
882	A:A:I245	A:A:V375	3.07	No	No	0	7	9
883	A:A:I288	A:A:V375	3.07	Yes	No	0	9	9
884	B:B:M262	B:B:S31	3.07	Yes	No	0	4	1
885	R:R:I309	R:R:V281	3.07	No	No	0	7	6
886	R:R:I323	R:R:V319	3.07	No	No	0	8	6
887	R:R:I400	R:R:V405	3.07	No	No	0	6	6
888	R:R:A209	R:R:Q210	3.03	No	No	0	1	4
889	A:A:L393	R:R:S352	3	No	No	0	8	9
890	B:B:L4	G:G:S8	3	No	No	0	4	4
891	B:B:L318	B:B:S277	3	No	No	0	6	5
892	R:R:K351	R:R:T355	3	No	No	0	8	8
893	B:B:L285	B:B:V276	2.98	Yes	No	0	6	6
894	R:R:L231	R:R:V281	2.98	No	No	0	5	6
895	R:R:L245	R:R:V319	2.98	No	No	0	8	6
896	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
897	R:R:D215	R:R:S219	2.94	No	No	0	3	5
898	G:G:A43	G:G:H44	2.93	No	No	0	4	6
899	R:R:I196	R:R:M233	2.92	No	No	0	5	6
900	G:G:I28	G:G:K32	2.91	No	No	0	4	5
901	R:R:I345	R:R:K336	2.91	No	No	0	5	6
902	R:R:I345	R:R:K346	2.91	No	No	0	5	6
903	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
904	A:A:Q294	A:A:V334	2.87	No	No	0	6	4
905	A:A:E330	A:A:V334	2.85	Yes	No	0	3	4
906	B:B:E10	G:G:V16	2.85	Yes	No	0	8	7
907	R:R:I146	R:R:L142	2.85	No	No	0	4	3
908	R:R:I147	R:R:L388	2.85	No	No	0	6	7
909	R:R:Q211	R:R:T207	2.83	No	No	0	4	3
910	R:R:K346	R:R:L349	2.82	No	No	0	6	9
911	R:R:E364	R:R:T391	2.82	No	No	0	8	6
912	A:A:K293	A:A:N292	2.8	No	Yes	0	9	9
913	B:B:C25	G:G:R27	2.79	No	Yes	0	3	8
914	A:A:A269	A:A:F246	2.77	No	Yes	0	9	9
915	A:A:A337	A:A:F315	2.77	No	No	0	8	6
916	A:A:R385	R:R:A337	2.77	Yes	No	0	5	7
917	B:B:A21	G:G:R27	2.77	No	Yes	0	4	8
918	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
919	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
920	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
921	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
922	G:G:A10	G:G:R13	2.77	No	No	0	2	6
923	R:R:L307	R:R:L311	2.77	No	No	0	7	4
924	R:R:L311	R:R:L314	2.77	No	No	0	4	4
925	R:R:A399	R:R:F404	2.77	No	Yes	0	8	8
926	R:R:N406	R:R:N407	2.72	No	No	0	9	6
927	A:A:K271	A:A:Q267	2.71	No	No	0	5	4
928	B:B:E12	B:B:K15	2.7	No	No	0	4	6
929	A:A:Y37	B:B:A56	2.67	Yes	No	0	4	7
930	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
931	R:R:F369	R:R:V365	2.62	No	No	0	4	6
932	R:R:A208	R:R:W214	2.59	No	No	0	4	1
933	R:R:F321	R:R:T362	2.59	No	No	0	6	7
934	R:R:V287	R:R:Y291	2.52	No	No	0	4	3
935	A:A:F340	A:A:I341	2.51	Yes	No	0	7	8
936	B:B:I123	B:B:R137	2.51	Yes	No	12	6	5
937	B:B:I171	B:B:R137	2.51	No	No	12	6	5
938	R:R:F385	R:R:I382	2.51	No	No	0	6	4
939	B:B:K23	B:B:R19	2.48	No	No	0	2	4
940	R:R:L314	R:R:R310	2.43	No	Yes	0	4	6
941	R:R:L335	R:R:R348	2.43	No	No	0	8	8
942	A:A:D223	A:A:F208	2.39	No	No	0	9	5
943	A:A:F312	A:A:Q267	2.34	Yes	No	0	8	4
944	R:R:F381	R:R:Q140	2.34	No	No	0	4	4
945	B:B:R46	R:R:E423	2.33	No	No	0	5	4
946	A:A:F312	A:A:Y311	2.06	Yes	No	0	8	6
947	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
948	A:A:A226	A:A:G206	1.95	No	No	0	9	8
949	B:B:A193	B:B:P194	1.87	No	No	0	4	4
950	R:R:G216	R:R:S219	1.86	No	No	0	2	5
951	B:B:G306	B:B:V296	1.84	No	No	0	4	5
952	B:B:G182	B:B:T181	1.82	No	No	0	6	2
953	B:B:A60	B:B:C103	1.81	No	No	0	7	8
954	R:R:A158	R:R:A399	1.79	No	No	0	7	8
955	R:R:P283	R:R:V282	1.77	No	No	0	5	3
956	B:B:P107	B:B:T65	1.75	No	No	0	6	1
957	G:G:P53	G:G:T52	1.75	No	No	0	8	4
958	R:R:G285	R:R:K288	1.74	No	No	0	5	8
959	A:A:G47	A:A:L46	1.71	No	No	0	9	8
960	B:B:A28	G:G:S31	1.71	No	No	0	4	9
961	R:R:A158	R:R:S157	1.71	No	No	0	7	3
962	B:B:A26	G:G:V30	1.7	No	No	0	3	8
963	B:B:A231	B:B:V276	1.7	No	No	0	5	6
964	R:R:I308	R:R:P283	1.69	No	No	0	8	5
965	A:A:D354	A:A:G353	1.68	No	No	0	3	4
966	A:A:D354	A:A:G355	1.68	No	No	0	3	2
967	B:B:D246	B:B:G272	1.68	Yes	No	0	9	4
968	B:B:D290	B:B:G272	1.68	Yes	No	0	6	4
969	A:A:E330	A:A:G329	1.64	Yes	No	0	3	7
970	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
971	R:R:S271	R:R:V270	1.62	No	No	0	3	5
972	R:R:S333	R:R:V332	1.62	No	No	0	7	6
973	B:B:D38	B:B:P39	1.61	No	No	0	1	1
974	A:A:V217	R:R:V259	1.6	No	No	0	5	6
975	B:B:S31	B:B:T29	1.6	No	No	0	1	3
976	R:R:T149	R:R:V150	1.59	No	No	0	7	5
977	R:R:C236	R:R:L232	1.59	No	No	0	5	5
978	B:B:L7	G:G:A12	1.58	No	No	0	8	5
979	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
980	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
981	A:A:E327	A:A:P328	1.57	No	No	0	4	1
982	A:A:A249	A:A:N292	1.56	No	Yes	0	8	9
983	R:R:C347	R:R:D344	1.56	No	No	0	7	7
984	R:R:I188	R:R:V160	1.54	No	No	0	7	3
985	R:R:I286	R:R:V282	1.54	No	No	0	4	3
986	R:R:I308	R:R:V287	1.54	No	No	0	8	4
987	R:R:I366	R:R:V370	1.54	No	No	0	6	5
988	R:R:I366	R:R:T362	1.52	No	No	0	6	7
989	A:A:A18	A:A:E21	1.51	No	No	0	4	2
990	R:R:G377	R:R:R376	1.5	No	No	0	4	5
991	R:R:L154	R:R:V150	1.49	No	No	0	5	5
992	R:R:L228	R:R:V229	1.49	No	No	0	4	7
993	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
994	A:A:N218	A:A:T40	1.46	No	No	0	4	7
995	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
996	A:A:F312	A:A:P313	1.44	Yes	No	0	8	6
997	A:A:P313	A:A:R317	1.44	No	No	0	6	2
998	G:G:K20	G:G:M21	1.44	No	No	0	6	1
999	R:R:I357	R:R:L354	1.43	No	No	0	8	8
1000	R:R:Q410	R:R:V405	1.43	No	No	0	7	6
1001	R:R:G275	R:R:W274	1.41	No	Yes	0	6	9
1002	B:B:D20	B:B:K23	1.38	No	No	0	2	2
1003	R:R:N302	R:R:N304	1.36	No	No	0	5	3
1004	A:A:E21	A:A:K25	1.35	No	No	0	2	5
1005	B:B:D267	B:B:N268	1.35	No	No	0	3	4
1006	G:G:E17	G:G:K20	1.35	No	No	0	6	6
1007	G:G:E47	G:G:K46	1.35	No	No	0	3	1
1008	B:B:E10	B:B:L7	1.33	Yes	No	0	8	8
1009	G:G:L15	G:G:Q11	1.33	No	No	0	2	3
1010	R:R:L218	R:R:Q221	1.33	No	No	0	3	4
1011	A:A:E15	A:A:N14	1.31	No	No	0	6	3
1012	B:B:D20	B:B:Q17	1.31	No	Yes	0	2	4
1013	R:R:E292	R:R:N302	1.31	No	No	0	6	5
1014	A:A:D229	A:A:E230	1.3	No	No	0	8	9
1015	R:R:L224	R:R:Y289	1.17	No	No	0	3	3
1016	R:R:D293	R:R:Y289	1.15	No	No	0	7	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:E16	7.4025	4	2	4
2	A:A:Q19	9.705	4	2	4
3	A:A:K34	7.11	4	2	4
4	A:A:Q35	5.9275	4	0	3
5	A:A:Y37	9.37	4	2	4
6	A:A:R38	5.62	4	2	4
7	A:A:F219	7.334	5	0	8
8	A:A:H220	7.8075	4	1	7
9	A:A:F222	9.17	4	1	7
10	A:A:Q227	5.556	5	1	9
11	A:A:K233	6.09	6	1	9
12	A:A:W234	6.17143	7	1	9
13	A:A:F238	8.93	5	0	9
14	A:A:F246	5.294	5	0	9
15	A:A:F273	6.23625	8	7	9
16	A:A:W277	10.59	5	7	6
17	A:A:W281	8.75333	6	1	5
18	A:A:I288	4.9725	4	0	9
19	A:A:F290	6.108	5	16	9
20	A:A:N292	3.295	4	0	9
21	A:A:F312	3.368	5	23	8
22	A:A:E330	3.48	4	0	3
23	A:A:Y339	5.23	4	13	3
24	A:A:F340	9.92667	6	23	7
25	A:A:E344	9.1875	4	23	5
26	A:A:F345	8.6775	4	7	8
27	A:A:R356	10.7375	4	0	2
28	A:A:Y358	7.47	4	0	4
29	A:A:Y360	9.3725	4	0	8
30	A:A:F363	10.215	4	13	5
31	A:A:T364	4.8275	4	16	9
32	A:A:R373	7.755	4	15	5
33	A:A:R374	6.0925	4	16	4
34	A:A:F376	7.8	5	15	8
35	A:A:R385	9.734	5	19	5
36	A:A:H387	8.3525	4	3	8
37	A:A:Y391	5.88667	6	3	4
38	B:B:E10	5.545	4	0	8
39	B:B:Q17	4.1575	4	0	4
40	B:B:I18	4.93	4	0	7
41	B:B:V40	5.4975	4	8	3
42	B:B:R48	6.815	4	2	7
43	B:B:L51	8.0925	4	0	9
44	B:B:H54	9.992	5	2	9
45	B:B:L55	7.8025	4	2	6
46	B:B:K57	10.764	5	1	9
47	B:B:Y59	8.244	5	1	8
48	B:B:W63	6.018	5	0	7
49	B:B:R68	12.76	4	2	5
50	B:B:V71	4.1575	4	6	8
51	B:B:D76	7.9425	4	2	9
52	B:B:K78	5.8425	4	0	8
53	B:B:I80	9.4	4	2	8
54	B:B:W82	11.18	5	2	9
55	B:B:D83	8.6875	4	2	8
56	B:B:T86	7.944	5	2	6
57	B:B:K89	6.07667	6	2	9
58	B:B:L95	5.662	5	6	8
59	B:B:W99	7.84286	7	1	9
60	B:B:M101	6.415	4	1	9
61	B:B:Y105	4.49429	7	6	6
62	B:B:N110	6.455	4	12	4
63	B:B:Y111	6.608	5	12	4
64	B:B:V112	4.5875	4	6	8
65	B:B:C114	5.065	4	6	8
66	B:B:L117	4.8225	4	1	9
67	B:B:N119	4.6525	4	1	9
68	B:B:I123	4.854	5	12	6
69	B:B:Y124	5.58333	6	6	6
70	B:B:H142	8.232	5	9	9
71	B:B:Y145	5.9975	8	1	8
72	B:B:F151	3.56333	6	0	9
73	B:B:D163	7.75	4	9	9
74	B:B:W169	8.77714	7	9	8
75	B:B:D170	7.1975	4	20	9
76	B:B:F180	8.218	5	10	7
77	B:B:H183	9.486	5	0	9
78	B:B:L190	5.26	4	10	5
79	B:B:F199	7.12857	7	10	9
80	B:B:C204	6.21	5	1	7
81	B:B:K209	9.582	5	10	6
82	B:B:L210	6.2825	4	4	5
83	B:B:W211	9.562	5	10	8
84	B:B:Q220	7.318	5	4	7
85	B:B:F222	8.0125	4	4	8
86	B:B:H225	9.36571	7	4	9
87	B:B:D228	9.8425	4	1	9
88	B:B:I232	5.09	4	4	8
89	B:B:F234	6.5325	4	0	5
90	B:B:F235	6.35	5	17	6
91	B:B:P236	6.0175	4	17	7
92	B:B:F241	9.42	5	4	6
93	B:B:T243	6.832	5	4	8
94	B:B:D246	5.2625	4	1	9
95	B:B:D247	8.406	5	4	9
96	B:B:T249	8.2175	4	4	6
97	B:B:R251	10.495	6	4	8
98	B:B:F253	7.72167	6	4	6
99	B:B:D258	8.865	4	4	7
100	B:B:M262	7.7425	4	0	4
101	B:B:Y264	7.866	5	0	5
102	B:B:I269	3.93	5	11	4
103	B:B:F278	5.9725	4	17	7
104	B:B:R283	7.85667	6	8	9
105	B:B:L284	4.7225	4	0	5
106	B:B:L285	3.698	5	0	6
107	B:B:Y289	7.285	6	11	7
108	B:B:D290	6.558	5	1	6
109	B:B:N293	6.2825	4	11	5
110	B:B:N295	7.65833	6	11	6
111	B:B:W297	6.4725	4	11	8
112	B:B:D298	9.4575	4	8	9
113	B:B:R304	8.115	4	11	5
114	B:B:H311	9.438	5	14	9
115	B:B:R314	13.014	5	1	8
116	B:B:W332	11.3857	7	1	9
117	B:B:D333	6.584	5	14	9
118	B:B:K337	10.1375	4	14	6
119	B:B:W339	12.005	4	14	9
120	G:G:E22	6.095	4	0	9
121	G:G:R27	5.524	5	0	8
122	G:G:Y40	12.395	4	17	6
123	G:G:D48	6.926	5	0	9
124	G:G:L51	4.33833	6	8	6
125	G:G:N59	7.918	5	2	9
126	G:G:F61	6.52571	7	2	8
127	R:R:Y145	8.198	5	5	5
128	R:R:Y148	9.1925	4	5	7
129	R:R:Y152	10.384	5	5	7
130	R:R:F156	6.5175	4	0	7
131	R:R:L159	5.0925	4	3	9
132	R:R:F169	7.2225	4	18	7
133	R:R:L172	7.295	4	18	9
134	R:R:R176	5.092	5	3	9
135	R:R:N177	5.7575	4	3	9
136	R:R:H180	6.506	5	3	9
137	R:R:F187	8.72286	7	3	8
138	R:R:R190	9.1425	4	0	8
139	R:R:L201	8.566	5	5	7
140	R:R:K202	6.2275	4	5	4
141	R:R:W203	8.5425	4	5	3
142	R:R:Y220	7.528	5	5	3
143	R:R:N240	9.8025	4	3	9
144	R:R:Y241	8.9375	4	0	8
145	R:R:Y242	6.554	5	25	6
146	R:R:W243	9.72571	7	3	9
147	R:R:E247	7.95	5	3	9
148	R:R:Y250	6.384	5	3	8
149	R:R:L255	4.1425	4	0	8
150	R:R:F266	6.4825	4	0	6
151	R:R:Y269	4.73	5	0	7
152	R:R:W274	9.252	5	3	9
153	R:R:W284	9.2325	4	0	8
154	R:R:W297	11.656	5	5	8
155	R:R:W306	9.7775	4	21	6
156	R:R:R310	5.9125	4	21	6
157	R:R:K334	9.305	4	19	9
158	R:R:H363	7.8125	4	0	8
159	R:R:F367	6.125	4	0	7
160	R:R:E373	4.845	4	22	4
161	R:R:R380	6.33	4	0	5
162	R:R:Y402	9.9	4	3	8
163	R:R:F404	4.3225	4	0	8
164	R:R:E412	10.125	4	18	8
165	W:W:?1	11.7042	12	5	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:Q19	B:B:D83	44.2333	6.53	Yes	Yes	2	4	8
2	B:B:D83	B:B:T86	44.2263	8.67	Yes	Yes	2	8	6
3	A:A:Q19	B:B:N88	44.121	15.85	Yes	No	2	4	7
4	B:B:N88	B:B:T86	44.2295	8.77	No	Yes	2	7	6
5	A:A:N23	B:B:N88	88.2724	12.26	No	No	2	7	7
6	A:A:N23	B:B:K89	88.0576	5.6	No	Yes	2	7	9
7	B:B:I80	B:B:K89	87.2898	5.82	Yes	Yes	2	8	9
8	B:B:H54	B:B:I80	92.0057	13.26	Yes	Yes	2	9	8
9	B:B:D76	B:B:H54	98.1382	3.78	Yes	Yes	2	9	9
10	B:B:D76	B:B:L55	97.3704	10.86	Yes	Yes	2	9	6
11	A:A:R38	B:B:L55	96.018	4.86	Yes	Yes	2	4	6
12	A:A:R38	R:R:E262	96.1741	4.65	Yes	No	0	4	6
13	B:B:D83	B:B:L69	94.2002	4.07	Yes	No	0	8	5
14	B:B:L69	B:B:Y105	100	5.86	No	Yes	0	5	6
15	B:B:L126	B:B:Y105	36.4925	3.52	No	Yes	6	5	6
16	B:B:K127	B:B:L126	36.7248	4.23	No	No	0	4	5
17	B:B:K127	B:B:N110	36.5667	6.99	No	Yes	0	4	4
18	B:B:N110	B:B:Y111	36.0738	4.65	Yes	Yes	12	4	4
19	B:B:I123	B:B:Y111	34.9925	3.63	Yes	Yes	12	6	4
20	B:B:I123	B:B:L139	32.7444	4.28	Yes	No	0	6	9
21	B:B:L139	B:B:W169	32.0952	15.94	No	Yes	0	9	8
22	B:B:H142	B:B:W169	31.074	7.41	Yes	Yes	9	9	8
23	B:B:H142	B:B:S161	29.5223	16.74	Yes	No	9	9	9
24	B:B:G162	B:B:S161	29.4403	3.71	No	No	0	9	9
25	B:B:G162	B:B:Y145	29.2746	5.79	No	Yes	0	9	8
26	R:R:E262	R:R:F260	96.3272	3.5	No	No	0	6	7
27	R:R:F260	R:R:I265	96.2217	3.77	No	No	0	7	5
28	R:R:I265	R:R:Y269	96.0103	4.84	No	Yes	0	5	7
29	R:R:Y250	R:R:Y269	58.7664	4.96	Yes	Yes	0	8	7
30	R:R:L254	R:R:Y250	21.7332	12.89	No	Yes	0	8	8
31	A:A:H387	R:R:L254	21.5341	18	Yes	No	0	8	8
32	R:R:R176	R:R:Y250	18.8259	4.12	Yes	Yes	3	9	8
33	A:A:Q390	R:R:R176	26.7147	3.5	No	Yes	3	4	9
34	A:A:M386	A:A:Q390	25.3606	5.44	No	No	3	3	4
35	A:A:M386	A:A:R389	42.6889	3.72	No	No	0	3	4
36	A:A:R389	A:A:Y358	42.3049	6.17	No	Yes	0	4	4
37	A:A:Y358	A:A:Y360	13.5973	4.96	Yes	Yes	0	4	8
38	A:A:D378	A:A:Y360	13.6428	14.94	No	Yes	0	7	8
39	A:A:H387	A:A:M386	17.7128	5.25	Yes	No	3	8	3
40	A:A:G355	A:A:Y358	28.4212	4.35	No	Yes	0	2	4
41	A:A:D354	A:A:G355	28.0269	1.68	No	No	0	3	2
42	A:A:D354	A:A:R356	27.2376	10.72	No	Yes	0	3	2
43	A:A:H357	A:A:R356	26.0524	12.41	No	Yes	0	7	2
44	A:A:H357	A:A:W277	25.657	25.39	No	Yes	0	7	6
45	A:A:F273	A:A:W277	22.8556	8.02	Yes	Yes	7	9	6
46	A:A:Y391	R:R:Y250	18.6898	4.96	Yes	Yes	3	4	8
47	B:B:M101	B:B:Y145	18.5818	8.38	Yes	Yes	1	9	8
48	B:B:M101	B:B:Y59	18.0514	7.18	Yes	Yes	1	9	8
49	B:B:W332	B:B:Y59	17.5161	12.54	Yes	Yes	1	9	8
50	A:A:F273	A:A:F345	10.0508	8.57	Yes	Yes	7	9	8
51	A:A:Y391	R:R:E247	17.3249	4.49	Yes	Yes	3	4	9
52	B:B:N313	B:B:W332	16.3333	5.65	No	Yes	0	7	9
53	B:B:D333	B:B:N313	15.9677	4.04	Yes	No	0	9	7
54	B:B:D312	B:B:D333	10.9654	6.65	No	Yes	0	5	9
55	B:B:H62	B:B:Y105	81.5199	4.36	No	Yes	0	6	6
56	B:B:H62	B:B:R150	81.4216	16.93	No	No	0	6	6
57	B:B:C148	B:B:R150	81.3231	5.57	No	No	0	6	6
58	B:B:C148	B:B:L190	81.2244	4.76	No	Yes	0	6	5
59	B:B:F199	B:B:L190	79.962	7.31	Yes	Yes	10	9	5
60	B:B:F199	B:B:W211	77.8126	14.03	Yes	Yes	10	9	8
61	B:B:K209	B:B:W211	39.066	8.12	Yes	Yes	10	6	8
62	B:B:K209	B:B:T221	38.9203	12.01	Yes	No	0	6	7
63	B:B:T221	G:G:E22	38.7931	8.47	No	Yes	0	7	9
64	B:B:C218	B:B:W211	38.7598	5.22	No	Yes	10	5	8
65	B:B:C218	G:G:Q18	38.6347	9.16	No	No	0	5	9
66	G:G:E22	G:G:Q18	38.5076	5.1	Yes	No	0	9	9
67	B:B:I18	G:G:E22	72.2861	6.83	Yes	Yes	0	7	9
68	B:B:I18	B:B:R22	40.5403	3.76	Yes	No	0	7	6
69	B:B:I18	G:G:R27	27.3323	5.01	Yes	Yes	0	7	8
70	B:B:D258	B:B:R22	21.0795	11.91	Yes	No	0	7	6
71	B:B:D258	G:G:R27	21.0559	9.53	Yes	Yes	0	7	8
72	B:B:Q259	B:B:R22	19.2928	5.84	No	No	0	6	6
73	B:B:A257	B:B:Q259	18.3941	4.55	No	No	0	7	6
74	B:B:A257	B:B:D254	18.0943	4.63	No	No	0	7	9
75	B:B:D254	B:B:L261	17.4949	12.21	No	No	0	9	5
76	B:B:R68	B:B:Y85	11.5508	25.72	Yes	No	2	5	4
77	B:B:Y85	G:G:F61	10.0853	7.22	No	Yes	2	4	8
78	B:B:T321	B:B:W63	13.3584	10.92	No	Yes	0	7	7
79	B:B:D323	B:B:T321	12.868	7.23	No	No	24	7	7
80	B:B:D323	B:B:M325	12.6291	8.32	No	No	0	7	5
81	B:B:M325	G:G:P49	12.3857	5.03	No	No	0	5	7
82	G:G:D48	G:G:P49	12.1422	3.22	Yes	No	0	9	7
83	B:B:D258	B:B:Q220	10.2314	10.44	Yes	Yes	4	7	7
84	B:B:L210	B:B:Q220	12.6459	7.99	Yes	Yes	4	5	7
85	B:B:L210	B:B:L255	10.8293	4.15	Yes	No	0	5	6
86	B:B:D258	B:B:F222	31.2763	3.58	Yes	Yes	4	7	8
87	B:B:A193	B:B:F234	13.6078	4.16	No	Yes	0	4	5
88	B:B:F222	B:B:F253	21.0986	9.65	Yes	Yes	4	8	6
89	B:B:F253	B:B:T243	11.5209	9.08	Yes	Yes	4	6	8
90	B:B:L252	B:B:L261	13.5716	4.15	No	No	0	7	5
91	B:B:L252	B:B:Y264	13.2774	5.86	No	Yes	0	7	5
92	B:B:L285	B:B:Y264	10.1931	4.69	Yes	Yes	0	6	5
93	R:R:V246	R:R:Y269	37.4359	5.05	No	Yes	0	8	7
94	R:R:V246	R:R:W243	37.2744	6.13	No	Yes	0	8	9
95	R:R:S186	R:R:W243	34.3008	6.18	No	Yes	3	9	9
96	R:R:N240	R:R:S186	34.4304	5.96	Yes	No	3	9	9
97	R:R:F187	R:R:N240	13.4405	18.12	Yes	Yes	3	8	9
98	R:R:F187	R:R:Q394	13.1367	11.71	Yes	No	0	8	9
99	R:R:H363	R:R:Q394	12.7744	13.6	Yes	No	0	8	9
100	R:R:F367	R:R:H363	12.4582	3.39	Yes	Yes	0	7	8
101	R:R:E247	R:R:L183	20.4963	5.3	Yes	No	3	9	9
102	R:R:F187	R:R:L183	15.0029	4.87	Yes	No	3	8	9
103	R:R:N240	R:R:R190	36.3148	9.64	Yes	Yes	0	9	8
104	R:R:R190	R:R:Y152	35.1761	4.12	Yes	Yes	0	8	7
105	R:R:Y148	R:R:Y152	17.0584	15.89	Yes	Yes	5	7	7
106	R:R:Y148	W:W:?1	16.8368	4.42	Yes	Yes	5	7	0
107	R:R:V194	R:R:Y152	17.0595	16.4	No	Yes	5	7	7
108	R:R:V194	W:W:?1	16.8318	4.01	No	Yes	5	7	0
109	R:R:F230	W:W:?1	13.1978	7.22	No	Yes	0	5	0
110	R:R:F230	R:R:W284	12.2595	5.01	No	Yes	0	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:T149	R:R:Y145	8.74	5	No	Yes	7	5	2	1
R:R:D198	R:R:Y145	10.34	5	No	Yes	7	5	2	1
R:R:L201	R:R:Y145	7.03	5	Yes	Yes	7	5	1	1
R:R:K202	R:R:Y145	4.78	5	Yes	Yes	4	5	2	1
R:R:Y145	W:W:?1	10.1	5	Yes	Yes	5	0	1	0
R:R:Y148	R:R:Y152	15.89	5	Yes	Yes	7	7	1	2
R:R:V194	R:R:Y148	8.83	5	No	Yes	7	7	1	1
R:R:S392	R:R:Y148	7.63	5	No	Yes	9	7	2	1
R:R:Y148	W:W:?1	4.42	5	Yes	Yes	7	0	1	0
R:R:D198	R:R:T149	7.23	5	No	No	7	7	2	2
R:R:V194	R:R:Y152	16.4	5	No	Yes	7	7	1	2
R:R:S392	R:R:Y152	10.17	5	No	Yes	9	7	2	2
R:R:V194	W:W:?1	4.01	5	No	Yes	7	0	1	0
R:R:K197	R:R:M233	7.2	0	No	No	6	6	1	2
R:R:K197	W:W:?1	25.07	0	No	Yes	6	0	1	0
R:R:D198	R:R:K202	8.3	5	No	Yes	7	4	2	2
R:R:A200	W:W:?1	10.18	0	No	Yes	4	0	1	0
R:R:K202	R:R:L201	7.05	5	Yes	Yes	4	7	2	1
R:R:L201	R:R:M204	4.24	5	Yes	No	7	3	1	1
R:R:L201	R:R:Y205	14.07	5	Yes	No	7	3	1	2
R:R:L201	W:W:?1	10.44	5	Yes	Yes	7	0	1	0
R:R:K202	R:R:Y205	4.78	5	Yes	No	4	3	2	2
R:R:M204	R:R:W203	4.65	5	No	Yes	3	3	1	1
R:R:T207	R:R:W203	12.13	0	No	Yes	3	3	2	1
R:R:A208	R:R:W203	3.89	0	No	Yes	4	3	2	1
R:R:W203	W:W:?1	13.5	5	Yes	Yes	3	0	1	0
R:R:M204	W:W:?1	12.95	5	No	Yes	3	0	1	0
R:R:L217	W:W:?1	6.71	0	No	Yes	4	0	1	0
R:R:S225	R:R:Y220	7.63	0	No	Yes	3	3	2	1
R:R:C226	R:R:Y220	9.41	5	No	Yes	9	3	2	1
R:R:V229	R:R:Y220	6.31	0	No	Yes	7	3	2	1
R:R:W297	R:R:Y220	4.82	5	Yes	Yes	8	3	1	1
R:R:Y220	W:W:?1	9.47	5	Yes	Yes	3	0	1	0
R:R:Q221	R:R:W297	15.33	0	No	Yes	4	8	2	1
R:R:C226	R:R:C296	7.28	5	No	No	9	9	2	2
R:R:C226	R:R:W297	5.22	5	No	Yes	9	8	2	1
R:R:F230	R:R:Q234	14.05	0	No	No	5	7	1	2
R:R:F230	R:R:W284	5.01	0	No	Yes	5	8	1	2
R:R:F230	W:W:?1	7.22	0	No	Yes	5	0	1	0
R:R:C296	R:R:W297	6.53	5	No	Yes	9	8	2	1
R:R:W297	W:W:?1	26.38	5	Yes	Yes	8	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
38.89	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
37.50	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
37.50	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
35.29	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
33.33	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
33.33	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
33.33	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
33.33	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
33.33	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
31.82	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
31.58	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
31.58	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
31.25	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
31.25	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
30.00	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
30.00	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
29.41	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
29.41	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
29.41	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
29.41	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
29.41	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
29.41	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
29.41	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
29.41	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
29.41	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
29.41	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
29.41	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
29.41	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
29.41	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
29.41	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
29.41	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
29.41	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
29.41	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
28.57	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
28.57	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
28.57	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
28.57	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
28.00	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
28.00	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
27.78	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
27.78	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
27.78	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
27.27	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
27.27	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
27.27	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
26.92	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
26.67	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
26.67	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
26.67	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
26.67	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
26.67	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
26.67	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
26.67	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
26.32	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
26.32	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
26.32	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
26.32	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
26.32	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
26.09	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
26.09	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
26.09	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
25.93	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
25.00	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
25.00	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
25.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
25.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
25.00	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
25.00	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
25.00	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
25.00	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
25.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
25.00	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
25.00	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
25.00	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
25.00	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
25.00	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
25.00	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
25.00	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
24.24	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
24.24	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
24.00	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
23.81	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
23.81	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
23.81	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
23.53	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
23.53	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
23.53	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
23.53	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
23.53	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
23.53	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
23.53	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070-Cholesterol
23.53	Consensus	hca_on	Orthosteric Ligand	hca2_on
23.53	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
23.08	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
23.08	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
23.08	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
23.08	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
22.73	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
22.73	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
22.73	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
22.73	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
22.22	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
22.22	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
22.22	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
22.22	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
22.22	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
22.22	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
22.22	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
22.22	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
22.22	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
22.22	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
22.22	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
22.22	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
22.22	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
21.74	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
21.74	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
21.74	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
21.74	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
21.74	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
21.43	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
21.43	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
21.43	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
21.43	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
21.43	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
21.05	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
21.05	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
21.05	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
21.05	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
21.05	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
21.05	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
21.05	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
20.83	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
20.83	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
20.83	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
20.83	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
20.83	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
20.69	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
20.69	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
20.69	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
20.51	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
20.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
20.00	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
20.00	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
20.00	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
20.00	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
20.00	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
20.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
20.00	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
20.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
20.00	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
20.00	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
20.00	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
20.00	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
20.00	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
20.00	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
20.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
20.00	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
20.00	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
19.35	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
19.23	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
19.23	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
19.23	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
19.23	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
19.23	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
19.23	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
19.23	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
19.23	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
19.23	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
19.23	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
19.23	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
19.23	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
19.23	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
19.23	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
19.23	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
19.23	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
19.05	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
19.05	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
19.05	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
19.05	Single	6OS2	TRV026	6OS2-AT₁-TRV026
19.05	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
19.05	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
19.05	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
19.05	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
19.05	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
19.05	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
19.05	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
19.05	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
19.05	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116-Cholesterol
19.05	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
19.05	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
19.05	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
19.05	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
19.05	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
19.05	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
19.05	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
19.05	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
19.05	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
19.05	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
19.05	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
18.75	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
18.75	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
18.75	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
18.75	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
18.75	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
18.75	Single	8YRG	Fospropofol	8YRG-MRGPRX4-Fospropofol-chim(NtGi1-Gs-CtGq)/β1/γ2
18.75	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
18.75	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
18.52	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
18.52	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
18.52	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
18.52	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
18.52	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
18.52	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
18.52	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
18.52	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
18.52	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
18.52	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
18.52	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
18.52	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
18.18	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
18.18	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
18.18	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
18.18	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
18.18	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
18.18	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
18.18	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
18.18	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
18.18	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
18.18	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
18.18	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
18.18	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
18.18	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
18.18	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
18.18	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
18.18	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
18.18	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
17.86	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
17.86	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
17.86	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
17.86	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
17.86	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
17.86	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
17.86	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
17.86	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
17.86	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
17.86	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
17.86	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
17.65	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
17.65	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
17.65	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
17.65	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
17.65	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
17.65	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
17.65	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
17.65	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
17.65	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
17.65	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
17.39	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
17.39	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
17.39	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
17.39	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
17.39	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
17.39	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
17.39	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
17.39	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
17.39	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
17.39	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
17.39	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
17.39	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
17.24	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
17.24	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
17.24	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
17.24	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
17.24	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
17.24	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.67	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
16.67	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
16.67	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
16.67	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
16.67	Single	6IQL	L745870	6IQL-D₄-L745870
16.67	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
16.67	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
16.67	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
16.67	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
16.67	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
16.67	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
16.67	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
16.67	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
16.67	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
16.67	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
16.67	Single	7QA8	Peptide	7QA8-STE2-Peptide
16.67	Single	7QA8	Peptide	7QA8-STE2-Peptide
16.67	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
16.67	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
16.67	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
16.67	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
16.67	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
16.67	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
16.67	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
16.67	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
16.67	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
16.67	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
16.67	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
16.67	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
16.67	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
16.67	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
16.67	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
16.67	Single	8K9L	Damgo	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
16.67	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.67	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
16.67	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
16.67	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
16.67	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
16.67	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
16.67	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
16.67	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
16.67	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
16.67	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
16.67	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
16.67	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
16.67	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
16.67	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
16.67	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
16.67	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
16.67	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
16.13	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
16.13	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
16.13	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
16.13	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
16.13	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
16.13	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
16.13	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
16.13	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
16.13	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
16.13	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
16.13	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
16.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
16.00	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
16.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
16.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
16.00	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
16.00	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
16.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
16.00	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
16.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
16.00	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
16.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
16.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
16.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
16.00	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
16.00	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
16.00	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
16.00	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
16.00	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
15.79	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
15.79	Single	5DHG	C-35	5DHG-NOP-C-35
15.79	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
15.79	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
15.79	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
15.79	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
15.79	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
15.79	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
15.79	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
15.79	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
15.79	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
15.79	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
15.79	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
15.79	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
15.79	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
15.79	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
15.79	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
15.62	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
15.62	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
15.62	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
15.62	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
15.62	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
15.38	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
15.38	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
15.38	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
15.38	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
15.38	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
15.38	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
15.38	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
15.38	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
15.38	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
15.38	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
15.38	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
15.38	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
15.38	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
15.38	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
15.38	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
15.38	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
15.38	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
15.38	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
15.38	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
15.15	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
15.15	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
15.15	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
15.00	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
15.00	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
15.00	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
15.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
15.00	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
15.00	Single	7C4S	S1P	7C4S-S1P₃-S1P
15.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
15.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
15.00	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
15.00	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
15.00	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
15.00	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
15.00	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go1/β1/γ2
15.00	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
15.00	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
15.00	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
15.00	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
15.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
15.00	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
15.00	Consensus	dp_off	Orthosteric Ligand	dp2_off
15.00	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
15.00	Consensus	ep_off	Orthosteric Ligand	ep4_off
15.00	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
15.00	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
14.81	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
14.81	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
14.81	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
14.81	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
14.81	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
14.81	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
14.81	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
14.81	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
14.81	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
14.81	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
14.81	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
14.81	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
14.81	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
14.81	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
14.29	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
14.29	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
14.29	Single	5XR8	AM841	5XR8-CB₁-AM841
14.29	Single	5XRA	AM11542	5XRA-CB₁-AM11542
14.29	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
14.29	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
14.29	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
14.29	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
14.29	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
14.29	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
14.29	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
14.29	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
14.29	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
14.29	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
14.29	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
14.29	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
14.29	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
14.29	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
14.29	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
14.29	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
14.29	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
14.29	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
14.29	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
14.29	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
14.29	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
14.29	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
14.29	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
14.29	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
14.29	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
14.29	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
14.29	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
14.29	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
14.29	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
14.29	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
14.29	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
14.29	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
14.29	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
13.79	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
13.79	Single	6FJ3	PTH	6FJ3-PTH1-PTH
13.79	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
13.79	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
13.79	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
13.79	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
13.79	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
13.79	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
13.79	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
13.79	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
13.79	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
13.79	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
13.79	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
13.79	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
13.64	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
13.64	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
13.64	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
13.64	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
13.64	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
13.64	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
13.64	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
13.64	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
13.64	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
13.64	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
13.64	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
13.64	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
13.64	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
13.64	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
13.64	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
13.64	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
13.64	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
13.64	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
13.64	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
13.64	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
13.64	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
13.64	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
13.64	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
13.64	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
13.64	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
13.64	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
13.64	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
13.64	Consensus	orexin_on	Orthosteric Ligand	ox2_on
13.64	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
13.64	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
13.64	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
13.51	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
13.33	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
13.33	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
13.33	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
13.33	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
13.33	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
13.33	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
13.33	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
13.33	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
13.33	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
13.33	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
13.33	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
13.33	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
13.33	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
13.33	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
13.33	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
13.33	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
13.04	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
13.04	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
13.04	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
13.04	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
13.04	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
13.04	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
13.04	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
13.04	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
13.04	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
13.04	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
13.04	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
13.04	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
13.04	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
13.04	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
13.04	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
13.04	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
13.04	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
13.04	Consensus	endothelin_off	Orthosteric Ligand	etb_off
13.04	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
13.04	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
13.04	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
12.90	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
12.90	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
12.90	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.90	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
12.90	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
12.90	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
12.90	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
12.90	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
12.90	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
12.50	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
12.50	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
12.50	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
12.50	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
12.50	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
12.50	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
12.50	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
12.50	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
12.50	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
12.50	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
12.50	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
12.50	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
12.50	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
12.50	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
12.50	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
12.50	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
12.50	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
12.50	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
12.50	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
12.50	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
12.50	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
12.50	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
12.50	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
12.50	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
12.12	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
12.12	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
12.12	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
12.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
12.00	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
12.00	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
12.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
12.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
12.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
12.00	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
12.00	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
12.00	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
12.00	Single	8WKY	PG-934	8WKY-MC₄-PG-934
12.00	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
12.00	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.00	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
12.00	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
12.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	6LI0	C17	6LI0-GPR52-C17
11.76	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
11.76	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
11.76	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
11.76	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
11.76	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
11.76	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
11.76	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
11.76	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
11.76	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
11.76	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
11.54	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
11.54	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
11.54	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
11.54	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
11.54	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
11.54	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
11.54	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
11.54	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.54	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
11.54	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
11.54	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
11.54	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
11.54	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
11.54	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
11.54	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
11.54	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
11.43	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
11.43	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
11.43	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
11.43	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
11.43	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
11.43	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
11.11	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
11.11	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	5WS3	EMPA	5WS3-OX₂-EMPA
11.11	Single	6AKX	A4R	6AKX-CCR5-A4R
11.11	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
11.11	Single	6B73	MP1104	6B73-κ-MP1104
11.11	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
11.11	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
11.11	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
11.11	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
11.11	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
11.11	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
11.11	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
11.11	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
11.11	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
11.11	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
11.11	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
11.11	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
11.11	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
11.11	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
11.11	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
11.11	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
11.11	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
11.11	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
11.11	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
11.11	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
11.11	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
11.11	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
11.11	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
11.11	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
11.11	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
11.11	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
11.11	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
11.11	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
11.11	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
11.11	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
10.71	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
10.71	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
10.71	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
10.71	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
10.71	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
10.71	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
10.71	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
10.71	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.71	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
10.71	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
10.71	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
10.71	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
10.71	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
10.71	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
10.53	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
10.53	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
10.53	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
10.53	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
10.53	Single	6TPG	EMPA	6TPG-OX₂-EMPA
10.53	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
10.53	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
10.53	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.53	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
10.53	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
10.53	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
10.53	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
10.53	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
10.34	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
10.34	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
10.34	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
10.34	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
10.34	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
10.34	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
10.34	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.34	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
10.34	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
10.34	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
10.26	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
10.00	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
10.00	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
10.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
10.00	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
10.00	Single	6D27	CAY10471	6D27-DP₂-CAY10471
10.00	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
10.00	Single	6GPS	MK0812	6GPS-CCR2-MK0812
10.00	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.00	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
10.00	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
10.00	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
10.00	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
10.00	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
10.00	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
10.00	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
10.00	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
10.00	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
10.00	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
10.00	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
10.00	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
10.00	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
10.00	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
10.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
10.00	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
10.00	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Consensus	blt_on	Orthosteric Ligand	blt1_on
10.00	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
10.00	Consensus	cck_off	Orthosteric Ligand	ccka_off
10.00	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
10.00	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
10.00	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
10.00	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
10.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
10.00	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
10.00	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
10.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
9.68	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
9.68	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.68	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
9.68	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
9.68	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
9.68	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
9.68	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
9.52	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
9.52	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
9.52	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
9.52	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
9.52	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
9.52	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
9.52	Single	5WQC	EMPA	5WQC-OX₂-EMPA
9.52	Single	6GPX	MK0812	6GPX-CCR2-MK0812
9.52	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
9.52	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
9.52	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
9.52	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
9.52	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
9.52	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
9.52	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
9.52	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.52	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
9.52	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
9.52	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
9.52	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.52	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
9.52	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
9.52	Single	8WGB	W9R	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
9.52	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.52	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
9.52	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
9.52	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.52	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
9.52	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
9.52	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.52	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.38	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
9.38	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
9.38	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
9.38	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
9.38	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
9.38	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
9.38	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
9.38	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
9.38	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
9.38	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
9.09	Single	4DJH	JDTic	4DJH-κ-JDTic
9.09	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
9.09	Single	5TZR	MK8666	5TZR-FFA1-MK8666
9.09	Single	5V56	TC114	5V56-SMO-TC114
9.09	Single	5V57	TC114	5V57-SMO-TC114
9.09	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
9.09	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
9.09	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
9.09	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
9.09	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
9.09	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
9.09	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
9.09	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
9.09	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
9.09	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
9.09	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
9.09	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
9.09	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
9.09	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
9.09	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
9.09	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
9.09	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
9.09	Single	8E0G	BU72	8E0G-μ-BU72
9.09	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
9.09	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
9.09	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
9.09	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.09	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
9.09	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
9.09	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
9.09	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
9.09	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
9.09	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
9.09	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go1/β1/γ2
9.09	Single	9GE2	ML184	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
9.09	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
9.09	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.09	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.09	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
9.09	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
9.09	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
9.09	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
9.09	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
8.82	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
8.82	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
8.82	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
8.70	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
8.70	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
8.70	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
8.70	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
8.70	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
8.70	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
8.70	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
8.70	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
8.70	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
8.70	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
8.70	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
8.70	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
8.70	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
8.70	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
8.70	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
8.70	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
8.70	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
8.70	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
8.70	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
8.70	Single	8JWY	2-118	8JWY-A_2A-2-118
8.70	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
8.70	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
8.70	Single	8XJN	Cloprosetnol	8XJN-TP-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8XQJ	JN241	8XQJ-Apelin-JN241
8.70	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
8.70	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
8.70	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
8.70	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
8.70	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
8.70	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
8.70	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
8.70	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
8.70	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
8.70	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
8.70	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
8.70	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
8.57	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.33	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
8.33	Single	5X93	K-8794	5X93-ET_B-K-8794
8.33	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
8.33	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
8.33	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
8.33	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
8.33	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
8.33	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
8.33	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
8.33	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
8.33	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
8.33	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
8.33	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
8.33	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
8.33	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
8.33	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
8.33	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
8.33	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
8.33	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
8.33	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
8.33	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
8.33	Consensus	tp_on	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
8.11	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
8.00	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
8.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
8.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
8.00	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
8.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
8.00	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
8.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
8.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
8.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
8.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
8.00	Single	8XQJ	JN241	8XQJ-Apelin-JN241
8.00	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
8.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
8.00	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
7.69	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
7.69	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
7.69	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
7.69	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
7.69	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
7.69	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
7.69	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
7.69	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
7.69	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
7.69	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
7.69	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
7.69	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
7.69	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
7.69	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
7.69	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
7.69	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
7.69	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
7.69	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
7.69	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
7.69	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
7.69	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
7.41	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
7.41	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
7.41	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
7.41	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
7.41	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
7.41	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
7.41	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
7.41	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
7.32	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
7.14	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
7.14	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
7.14	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
7.14	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
7.14	Single	9IVM	LSN3318839	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
6.90	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
6.90	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
6.90	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
6.90	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
6.90	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
6.67	Single	6VCB	LSN3160440	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
6.67	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
6.67	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
6.67	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
6.67	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
6.67	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
6.67	Single	8HS2	Fab046	8HS2-GPR20-Fab046
6.67	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
6.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
6.67	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
6.67	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
6.25	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
6.25	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
6.25	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
6.25	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/β1/γ2
6.25	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
6.06	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
6.06	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
6.06	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
6.06	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
5.88	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
5.88	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
5.88	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
5.88	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.88	Single	7V6A	-	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
5.88	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
5.88	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
5.88	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
5.88	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.88	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.71	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
5.56	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
5.56	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
5.56	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
5.56	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
5.56	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
5.56	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
5.56	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
5.56	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
5.56	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.56	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
5.56	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go1/β1/γ2
5.56	Single	9B9Y	7DY	9B9Y-CB₁-7DY
5.56	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
5.26	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
5.26	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
5.26	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
5.26	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
5.26	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
5.26	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
5.26	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
5.26	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
5.26	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
5.26	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
5.26	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
5.26	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
5.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
5.26	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
5.26	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
5.26	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
5.26	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
5.26	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
5.26	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
5.26	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.26	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
5.26	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.26	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
5.26	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.26	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
5.26	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
5.26	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
5.00	Single	3REY	XAC	3REY-A_2A-XAC
5.00	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
5.00	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
5.00	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
5.00	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
5.00	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
5.00	Single	6TPK	Retosiban	6TPK-OT-Retosiban
5.00	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
5.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
5.00	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
5.00	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
5.00	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
5.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
5.00	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
5.00	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
5.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
5.00	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
5.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
5.00	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
5.00	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.00	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
5.00	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
5.00	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
5.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
5.00	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100-Cholesterol
5.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
5.00	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
5.00	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
5.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
5.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
5.00	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
5.00	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
4.76	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
4.76	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
4.76	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
4.76	Single	4QKX	35V	4QKX-β₂-35V
4.76	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
4.76	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
4.76	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
4.76	Single	6IIV	Daltroban	6IIV-TP-Daltroban
4.76	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
4.76	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
4.76	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
4.76	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
4.76	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
4.76	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
4.76	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
4.76	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
4.76	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
4.76	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
4.76	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.76	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
4.76	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
4.76	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
4.76	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
4.76	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
4.76	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
4.76	Single	8T1W	CVN424	8T1W-GPR6-CVN424
4.76	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
4.76	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
4.76	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
4.76	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
4.76	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
4.76	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
4.76	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9IMA	Talquetamab	9IMA-GPRC5D-Talquetamab
4.76	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
4.76	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
4.76	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.55	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
4.55	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
4.55	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
4.55	Single	5C1M	BU72	5C1M-μ-BU72
4.55	Single	5N2S	PSB36	5N2S-A₁-PSB36
4.55	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
4.55	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
4.55	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.55	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
4.55	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
4.55	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
4.55	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
4.55	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.55	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.55	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
4.55	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.55	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.55	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
4.55	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
4.55	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
4.55	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
4.55	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
4.55	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
4.55	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
4.55	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
4.55	Single	7W41	PD176252	7W41-BB₂-PD176252
4.55	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
4.55	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
4.55	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
4.55	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
4.55	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
4.55	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
4.55	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
4.55	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
4.55	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
4.55	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
4.55	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
4.55	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
4.55	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
4.55	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
4.55	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go1/β1/γ2
4.55	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
4.55	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
4.55	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
4.55	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
4.55	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.55	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.55	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.35	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
4.35	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
4.35	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
4.35	Single	6E59	L-760735	6E59-NK₁-L-760735
4.35	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
4.35	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
4.35	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
4.35	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
4.35	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
4.35	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
4.35	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
4.35	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
4.35	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
4.35	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
4.35	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
4.35	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
4.35	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
4.35	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
4.35	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
4.35	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
4.35	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
4.35	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
4.35	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
4.35	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
4.35	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
4.35	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
4.35	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
4.35	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
4.35	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
4.35	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
4.35	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
4.35	Consensus	a2_on	Orthosteric Ligand	a2b_on
4.35	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
4.35	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.35	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.35	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
4.35	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
4.35	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.35	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.35	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
4.35	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
4.35	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.35	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
4.35	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
4.35	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
4.35	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.35	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
4.17	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
4.17	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
4.17	Single	4LDE	BI167107	4LDE-β₂-BI167107
4.17	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
4.17	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
4.17	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
4.17	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
4.17	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
4.17	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
4.17	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
4.17	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
4.17	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.17	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
4.17	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
4.17	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
4.17	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.17	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
4.17	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
4.17	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
4.17	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.17	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.17	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
4.17	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
4.17	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
4.17	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
4.17	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
4.17	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.17	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
4.17	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.17	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.17	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.17	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.17	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
4.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
4.00	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
4.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
4.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
4.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
4.00	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
4.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
4.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
4.00	Single	7EZC	UKA	7EZC-A_2A-UKA
4.00	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
4.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
4.00	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
4.00	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
4.00	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
4.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
4.00	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
4.00	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
4.00	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
4.00	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
4.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
4.00	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.00	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
3.85	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
3.85	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
3.85	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
3.85	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
3.85	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
3.85	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
3.70	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
3.70	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
3.70	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
3.70	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
3.70	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.70	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
3.70	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
3.70	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
3.70	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
3.70	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
3.57	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
3.45	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
3.33	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
3.33	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
3.12	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
2.94	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2

PDB Summary
PDB	6ORV
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GLP-1
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	TT-OAD2
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	3
Date	2020-01-08
D.O.I.	10.1038/s41586-019-1902-z

Net Summary
I_min	3.5
Number of Linked Nodes	835
Number of Links	1016
Number of Hubs	165
Number of Links mediated by Hubs	613
Number of Communities	26
Number of Nodes involved in Communities	237
Number of Links involved in Communities	348

Path Summary
Number Of Nodes in MetaPath	111
Number Of Links MetaPath	110
Number of Shortest Paths	1774815
Length Of Smallest Path	3
Average Path Length	34.7093
Length of Longest Path	65
Minimum Path Strength	1.16
Average Path Strength	7.26233
Maximum Path Strength	25.725
Minimum Path Correlation	0.7
Average Path Correlation	0.982267
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.22222
Average % Of Corr. Nodes	40.3374
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	53.7635
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • glucagon receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • amide binding • peptide hormone binding • hormone binding • glucagon-like peptide 1 receptor activity • positive regulation of cytosolic calcium ion concentration • heart process • regulation of heart contraction • regulation of system process • circulatory system process • regulation of blood circulation • heart contraction • blood circulation • regulation of blood pressure • positive regulation of blood pressure • response to psychosocial stress • cell surface receptor signaling pathway • behavior • learning or memory • protein targeting • protein transmembrane transport • post-translational protein targeting to membrane, translocation • establishment of protein localization to endoplasmic reticulum • protein localization to endoplasmic reticulum • establishment of protein localization to membrane • intracellular protein transmembrane transport • post-translational protein targeting to endoplasmic reticulum membrane • localization within membrane • protein localization to membrane • protein targeting to membrane • transmembrane transport • establishment of protein localization to organelle • protein localization to organelle • intracellular protein transport • protein targeting to ER • negative regulation of blood pressure
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	N2V
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	N2V
Name	N-{(3S,8S)-3-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-7-[(1S)-1-phenylpropyl]-2,3,6,7,8,9-hexahydro[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl}-4-(2,3-dimethylpyridin-4-yl)-L-phenylalanine
Synonyms
Identifier
Formula	C50 H47 Cl2 N3 O6
Molecular Weight	856.831
SMILES
PubChem	58327143
Formal Charge	0
Total Atoms	108
Total Chiral Atoms	4
Total Bonds	115
Total Aromatic Bonds	36


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>6ORV_Chain_A D Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G S G I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V A N R L Q A A L K L F D S I W N N K W L R D T S V I L F L N K Q D I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T N I R R V F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>6ORV_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>6ORV_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>6ORV_Chain_R P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L S C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S V F S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F V R V I C I V V S K L K A D I K C R L A K S T L T L I P L L G T H E V I F A F V M D E H A R G T L R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	10.1038/s41421-024-00649-0
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	10.1073/pnas.2303696120
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	10.1073/pnas.2303696120
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	10.1016/j.apsb.2024.09.002
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	10.1021/jacs.4c12808
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	10.1073/pnas.2200155119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	10.1073/pnas.2200155119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	10.1073/pnas.2116506119
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	10.1073/pnas.2116506119
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	10.1038/s41467-022-28683-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	10.1038/s41467-021-27760-0
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	10.1038/s41589-021-00945-w
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	10.1038/s41467-021-24058-z
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	10.1038/s41467-021-24058-z
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	10.1016/j.str.2021.04.008
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	10.1073/pnas.2014879117
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	10.1038/s41422-020-0384-8
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	10.1038/s41589-020-0589-7
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	10.1038/s41586-019-1902-z
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	10.1038/nature25773
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	10.1038/nature22394
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 6ORV.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.