Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:W33 9.6275403
2R:R:W39 8.178515
3R:R:P56 7.7325491
4R:R:W72 10.535109
5R:R:D74 10.6275493
6R:R:P86 6.365618
7R:R:W87 6.0975403
8R:R:Y88 7.31515
9R:R:L89 5.385415
10R:R:P90 7.245414
11R:R:W91 6.426514
12R:R:Y101 8.2354115
13R:R:R102 14.8845108
14R:R:F103 6.8775404
15R:R:Y145 6.92425
16R:R:Y148 5.57571727
17R:R:Y152 8.1727
18R:R:L166 6.145408
19R:R:F169 8.14127
20R:R:R176 4.9469
21R:R:N177 5.705469
22R:R:F184 4.7125408
23R:R:F187 10.6575408
24R:R:R190 9.65667628
25R:R:K197 8.35526
26R:R:Y205 9.095403
27R:R:H212 5.3025413
28R:R:W214 7.5175411
29R:R:Y220 6.88403
30R:R:F230 5.4475405
31R:R:Y235 5.72409
32R:R:Y241 10.685428
33R:R:Y242 6.0925406
34R:R:W243 13.078579
35R:R:E247 10.4525409
36R:R:Y269 6.084507
37R:R:W274 8.426579
38R:R:W284 7.28429738
39R:R:E292 7.1025446
40R:R:W297 7.79333688
41R:R:R299 6.84333654
42R:R:Y305 7.384544
43R:R:W306 12.1617636
44R:R:L335 3.015408
45R:R:H363 12.2375408
46R:R:F367 5.055407
47R:R:Q394 7.6625409
48R:R:C403 4.73409
49R:R:E412 10.53754128
50L:L:H7 6.815630
51L:L:?8 8.8825430
52L:L:F12 6.164520
53L:L:E21 8.406550
54L:L:F28 7.404510
55L:L:W31 7.362510
56L:L:L32 7.5925410
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:E34 R:R:W33 96.186314.17NoYes043
2R:R:L218 R:R:W33 94.45594.56NoYes033
3R:R:L218 R:R:V36 94.09434.47NoNo032
4L:L:F28 R:R:V36 94.02155.24YesNo002
5L:L:F28 R:R:W39 49.02811.02YesYes105
6R:R:W39 R:R:Y88 38.795110.61YesYes155
7R:R:P86 R:R:Y88 41.19418.34YesYes185
8R:R:L89 R:R:P86 18.69586.57YesYes158
9L:L:F28 L:L:L32 38.0499.74YesYes100
10L:L:L32 R:R:Y88 38.2274.69YesYes105
11R:R:E34 R:R:S31 96.54168.62NoNo044
12R:R:R299 R:R:S31 47.23193.95YesNo544
13L:L:E21 R:R:S31 49.662510.06YesNo504
14R:R:F66 R:R:W39 11.20454.01NoYes075
15R:R:C46 R:R:C71 10.06047.28NoNo089
16R:R:C71 R:R:F66 10.6384.19NoNo097
17R:R:R121 R:R:W72 23.12744NoYes069
18L:L:V33 R:R:R121 26.36585.23NoNo006
19L:L:V33 R:R:Y69 27.44743.79NoNo006
20R:R:R102 R:R:W72 11.057323.99YesYes1089
21R:R:G98 R:R:H99 15.42964.77NoNo044
22R:R:C85 R:R:G98 18.69581.96NoNo094
23R:R:C85 R:R:P86 21.94773.77NoYes098
24L:L:E21 R:R:Y205 50.695111.22YesYes003
25L:L:T13 R:R:K197 98.23956.01NoYes206
26L:L:T13 R:R:L201 1004.42NoNo007
27R:R:L201 R:R:M204 52.13124.24NoNo073
28R:R:M204 R:R:Y205 51.56157.18NoYes033
29R:R:F230 R:R:L201 48.0697.31YesNo057
30R:R:F230 R:R:T298 47.7437.78YesNo055
31R:R:R299 R:R:T298 47.39255.17YesNo545
32L:L:E9 R:R:K197 86.66714.05NoYes206
33R:R:F187 R:R:N240 40.406816.92YesNo089
34R:R:N240 R:R:R190 57.24810.85NoYes098
35L:L:E9 R:R:R190 84.83239.3NoYes208
36R:R:L166 R:R:N177 15.86718.24YesYes089
37R:R:H180 R:R:N177 16.8153.83NoYes699
38R:R:E247 R:R:H180 20.035311.08YesNo099
39R:R:E247 R:R:L183 36.093111.93YesNo099
40R:R:F187 R:R:L183 35.85267.31YesNo089
41R:R:V246 R:R:W243 10.432211.03NoYes089
42R:R:S186 R:R:W243 11.67927.41NoYes799
43R:R:N240 R:R:S186 23.32445.96NoNo099
44R:R:S186 R:R:W274 11.14834.94NoYes799
45R:R:R190 R:R:V237 45.652611.77YesNo086
46R:R:K288 R:R:W284 13.33849.28NoYes088
47R:R:Q234 R:R:W284 17.190813.14NoYes378
48L:L:H7 R:R:Q234 17.66726.18YesNo307
49L:L:H7 R:R:V237 45.250715.22YesNo006
50R:R:W284 R:R:W306 17.5394.69YesYes386
51L:L:H7 R:R:W306 23.18757.41YesYes306
52R:R:E247 R:R:L359 16.947910.6YesNo099
53R:R:L359 R:R:L360 15.90044.15NoNo099
54R:R:Y69 R:R:Y88 27.57723.97NoYes165
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:P90 R:R:V30 5.3 1 Yes No 4 2 1 2
R:R:E34 R:R:S31 8.62 0 No No 4 4 2 1
R:R:R299 R:R:S31 3.95 5 Yes No 4 4 1 1
L:L:E21 R:R:S31 10.06 5 Yes No 0 4 0 1
L:L:E21 R:R:L32 5.3 5 Yes No 0 4 0 1
R:R:P90 R:R:T35 10.49 1 Yes No 4 5 1 1
R:R:R40 R:R:V36 6.54 0 No No 2 2 2 1
R:R:L218 R:R:V36 4.47 0 No No 3 2 2 1
L:L:F28 R:R:V36 5.24 1 Yes No 0 2 0 1
R:R:R43 R:R:W39 5 0 No Yes 4 5 2 1
R:R:F66 R:R:W39 4.01 0 No Yes 7 5 2 1
R:R:W39 R:R:Y88 10.61 1 Yes Yes 5 5 1 1
L:L:F28 R:R:W39 11.02 1 Yes Yes 0 5 0 1
L:L:L32 R:R:W39 10.25 1 Yes Yes 0 5 0 1
R:R:P86 R:R:Y42 5.56 1 Yes No 8 6 2 2
R:R:Y42 R:R:Y88 8.94 1 No Yes 6 5 2 1
L:L:?35 R:R:E68 3.81 1 No No 0 4 0 1
L:L:R36 R:R:E68 5.82 1 No No 0 4 0 1
R:R:P86 R:R:Y69 8.34 1 Yes No 8 6 2 1
R:R:Y69 R:R:Y88 3.97 1 No Yes 6 5 1 1
L:L:V33 R:R:Y69 3.79 0 No No 0 6 0 1
R:R:R121 R:R:W72 4 0 No Yes 6 9 1 2
R:R:P86 R:R:Y88 8.34 1 Yes Yes 8 5 2 1
R:R:L89 R:R:P86 6.57 1 Yes Yes 5 8 1 2
L:L:L32 R:R:Y88 4.69 1 Yes Yes 0 5 0 1
R:R:L89 R:R:W91 9.11 1 Yes Yes 5 4 1 1
L:L:I29 R:R:L89 4.28 1 No Yes 0 5 0 1
R:R:P90 R:R:W91 8.11 1 Yes Yes 4 4 1 1
L:L:I29 R:R:P90 5.08 1 No Yes 0 4 0 1
R:R:E128 R:R:W91 5.45 0 No Yes 3 4 2 1
L:L:I29 R:R:W91 8.22 1 No Yes 0 4 0 1
R:R:L123 R:R:R121 4.86 0 No No 5 6 2 1
L:L:V33 R:R:R121 5.23 0 No No 0 6 0 1
L:L:Y19 R:R:E138 7.86 0 No No 0 2 0 1
L:L:F12 R:R:L141 6.09 2 Yes No 0 5 0 1
R:R:F381 R:R:L144 7.31 0 No No 4 6 2 1
L:L:F12 R:R:L144 6.09 2 Yes No 0 6 0 1
R:R:Y145 R:R:Y148 4.96 2 Yes Yes 5 7 2 1
R:R:D198 R:R:Y145 9.2 2 No Yes 7 5 2 2
R:R:Y148 R:R:Y152 3.97 2 Yes Yes 7 7 1 1
R:R:V194 R:R:Y148 5.05 2 No Yes 7 7 2 1
R:R:D198 R:R:Y148 8.05 2 No Yes 7 7 2 1
R:R:L388 R:R:Y148 4.69 2 No Yes 7 7 1 1
R:R:S392 R:R:Y148 5.09 2 No Yes 9 7 2 1
L:L:F12 R:R:Y148 7.22 2 Yes Yes 0 7 0 1
R:R:R190 R:R:Y152 7.2 2 Yes Yes 8 7 1 1
R:R:A191 R:R:Y152 5.34 0 No Yes 7 7 2 1
R:R:V194 R:R:Y152 12.62 2 No Yes 7 7 2 1
R:R:S392 R:R:Y152 16.53 2 No Yes 9 7 2 1
L:L:E9 R:R:Y152 8.98 2 No Yes 0 7 0 1
R:R:R190 R:R:V237 11.77 2 Yes No 8 6 1 1
R:R:N240 R:R:R190 10.85 0 No Yes 9 8 2 1
R:R:R190 R:R:Y241 12.35 2 Yes Yes 8 8 1 2
R:R:R190 R:R:T391 6.47 2 Yes No 8 6 1 2
L:L:E9 R:R:R190 9.3 2 No Yes 0 8 0 1
R:R:K197 R:R:V194 9.11 2 Yes No 6 7 1 2
R:R:D198 R:R:K197 11.06 2 No Yes 7 6 2 1
R:R:K197 R:R:M233 11.52 2 Yes No 6 6 1 1
L:L:E9 R:R:K197 4.05 2 No Yes 0 6 0 1
L:L:T13 R:R:K197 6.01 2 No Yes 0 6 0 1
R:R:L201 R:R:M204 4.24 0 No No 7 3 1 2
R:R:F230 R:R:L201 7.31 0 Yes No 5 7 2 1
L:L:T13 R:R:L201 4.42 2 No No 0 7 0 1
R:R:M204 R:R:Y205 7.18 0 No Yes 3 3 2 1
L:L:S17 R:R:Y205 5.09 5 No Yes 0 3 0 1
L:L:L20 R:R:Y205 12.89 0 No Yes 0 3 0 1
L:L:E21 R:R:Y205 11.22 5 Yes Yes 0 3 0 1
R:R:H212 R:R:W214 7.41 1 Yes Yes 3 1 1 1
L:L:W31 R:R:H212 7.41 1 Yes Yes 0 3 0 1
L:L:K34 R:R:H212 3.93 1 No Yes 0 3 0 1
L:L:F28 R:R:W214 6.01 1 Yes Yes 0 1 0 1
L:L:W31 R:R:W214 14.06 1 Yes Yes 0 1 0 1
R:R:L217 R:R:Q221 5.32 0 No No 4 4 2 1
L:L:E21 R:R:Q221 3.82 5 Yes No 0 4 0 1
R:R:F230 R:R:T298 7.78 0 Yes No 5 5 2 1
L:L:T13 R:R:M233 4.52 2 No No 0 6 0 1
R:R:Q234 R:R:W284 13.14 3 No Yes 7 8 1 2
R:R:Q234 R:R:W306 7.67 3 No Yes 7 6 1 1
L:L:H7 R:R:Q234 6.18 3 Yes No 0 7 0 1
L:L:H7 R:R:V237 15.22 3 Yes No 0 6 0 1
R:R:I313 R:R:Y241 10.88 0 No Yes 7 8 1 2
R:R:W284 R:R:W306 4.69 3 Yes Yes 8 6 2 1
R:R:I309 R:R:W284 14.09 3 No Yes 7 8 2 2
R:R:G295 R:R:R299 4.5 0 No Yes 4 4 2 1
R:R:R299 R:R:T298 5.17 5 Yes No 4 5 1 1
L:L:S17 R:R:T298 7.99 5 No No 0 5 0 1
L:L:S17 R:R:R299 10.54 5 No Yes 0 4 0 1
L:L:S18 R:R:R299 5.27 0 No Yes 0 4 0 1
L:L:E21 R:R:R299 11.63 5 Yes Yes 0 4 0 1
R:R:N300 R:R:W306 25.99 0 No Yes 6 6 1 1
L:L:S14 R:R:N300 5.96 0 No No 0 6 0 1
R:R:D372 R:R:M303 6.93 0 No No 5 5 1 2
R:R:I309 R:R:W306 8.22 3 No Yes 7 6 2 1
R:R:R310 R:R:W306 18.99 0 No Yes 6 6 2 1
L:L:H7 R:R:W306 7.41 3 Yes Yes 0 6 0 1
L:L:H7 R:R:I313 3.98 3 Yes No 0 7 0 1
R:R:D372 R:R:R380 9.53 0 No No 5 5 1 1
L:L:T11 R:R:D372 7.23 3 No No 0 5 0 1
R:R:R376 R:R:R380 4.26 0 No No 5 5 2 1
L:L:D15 R:R:R380 8.34 0 No No 0 5 0 1
R:R:E387 R:R:K383 4.05 0 No No 8 7 1 2
L:L:?8 R:R:L384 6.63 3 Yes No 0 5 0 1
L:L:T11 R:R:L384 5.9 3 No No 0 5 0 1
L:L:?8 R:R:E387 12.69 3 Yes No 0 8 0 1
L:L:F12 R:R:L388 4.87 2 Yes No 0 7 0 1
R:R:F385 R:R:L144 3.65 0 No No 6 6 2 1
L:L:A25 R:R:T35 3.36 0 No No 0 5 0 1
R:R:A238 R:R:I313 3.25 0 No No 6 7 2 1
R:R:E138 R:R:P137 3.14 0 No No 2 3 1 2
R:R:M233 R:R:S193 3.07 2 No No 6 6 1 2
R:R:A209 R:R:W214 2.59 0 No Yes 1 1 1 1
L:L:E27 R:R:H212 2.46 0 No Yes 0 3 0 1
R:R:F195 R:R:Y152 2.06 0 No Yes 7 7 2 1
L:L:A24 R:R:A209 1.79 0 No No 0 1 0 1
R:R:A92 R:R:L89 1.58 0 No Yes 5 5 2 1
R:R:S94 R:R:W91 1.24 0 No Yes 4 4 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7KI1_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.79
Number of Linked Nodes 375
Number of Links 424
Number of Hubs 56
Number of Links mediated by Hubs 222
Number of Communities 13
Number of Nodes involved in Communities 80
Number of Links involved in Communities 106
Path Summary
Number Of Nodes in MetaPath 55
Number Of Links MetaPath 54
Number of Shortest Paths 182590
Length Of Smallest Path 3
Average Path Length 21.688
Length of Longest Path 43
Minimum Path Strength 1.44
Average Path Strength 7.44307
Maximum Path Strength 24.49
Minimum Path Correlation 0.7
Average Path Correlation 0.962195
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.22581
Average % Of Corr. Nodes 61.7996
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 42.0891
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• G protein-coupled receptor-like   • FnI-like domain   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• G protein-coupled receptor-like   • FnI-like domain   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeAIB
PDB ResiduesL:L:?8 L:L:?35
Environment DetailsOpen EMBL-EBI Page
CodeAIB
Name2-aminoisobutyric acid
Synonyms2-aminoisobutyric acid
Identifier
FormulaC4 H9 N O2
Molecular Weight103.12
SMILES
PubChem5245672
Formal Charge0
Total Atoms16
Total Chiral Atoms0
Total Bonds15
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP43220
Sequence
>7KI1_nogp_Chain_R
TVSLWETVQ KWREYRRQC QRSLTEDPP PATDLFCNR TFDEYACWP 
DGEPGSFVN VSCPWYLPW ASSVPQGHV YRFCTAEGL WLQKDNSSL 
PWRDLSECE ESPEEQLLF LYIIYTVGY ALSFSALVI ASAILLGFR 
HLHCTRNYI HLNLFASFI LRALSVFIK DAALKWMYS TAAQQHQWD 
GLLSYQDSL SCRLVFLLM QYCVAANYY WLLVEGVYL YTLLAFSVF 
SEQWIFRLY VSIGWGVPL LFVVPWGIV KYLYEDEGC WTRNSNMNY 
WLIIRLPIL FAIGVNFLI FVRVICIVV SKLKANLTD IKCRLAKST 
LTLIPLLGT HEVIFAFVM DEHARGTLR FIKLFTELS FTSFQGLMV 
AILYCFVNN EVQLEFRKS WERWRLE


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainL
ProteinTaspoglutide
UniProtP01275
Sequence
>7KI1_nogp_Chain_L


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5VEXB1PeptideGlucagonGLP-1Homo sapiens-NNC0640-32017-05-17doi.org/10.1038/nature22378
5VAIB1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-Gs/β1/γ24.12017-05-24doi.org/10.1038/nature22394
5VAI (No Gprot) B1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-4.12017-05-24doi.org/10.1038/nature22394
5VEWB1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.72017-05-24doi.org/10.1038/nature22378
5NX2B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)--3.72017-06-14doi.org/10.1038/nature22800
6B3JB1PeptideGlucagonGLP-1Homo sapiensExendin-P5-Gs/β1/γ23.32018-02-21doi.org/10.1038/nature25773
6B3J (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-P5-3.32018-02-21doi.org/10.1038/nature25773
6KJVB1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.82019-11-13doi.org/10.1107/S2052252519013496
6KK1B1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.82019-11-13doi.org/10.1107/S2052252519013496
6KK7B1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-3.12019-11-13doi.org/10.1107/S2052252519013496
6ORVB1PeptideGlucagonGLP-1Homo sapiens-TT-OAD2Gs/β1/γ232020-01-08doi.org/10.1038/s41586-019-1902-z
6ORV (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-TT-OAD232020-01-08doi.org/10.1038/s41586-019-1902-z
6LN2B1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-3.22020-03-18doi.org/10.1038/s41467-020-14934-5
6VCBB1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN3160440Gs/β1/γ23.32020-07-22doi.org/10.1038/s41589-020-0589-7
6VCB (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN31604403.32020-07-22doi.org/10.1038/s41589-020-0589-7
7C2EB1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-Gs/β1/γ24.22020-08-26doi.org/10.1038/s41422-020-0384-8
7C2E (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-4.22020-08-26doi.org/10.1038/s41422-020-0384-8
6X18B1PeptideGlucagonGLP-1Homo sapiensGLP-1-Gs/β1/γ22.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X18 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1-2.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X19B1PeptideGlucagonGLP-1Homo sapiensCHU-128-Gs/β1/γ22.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X19 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensCHU-128-2.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X1AB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/β1/γ22.52020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X1A (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensDanuglipron-2.52020-09-09doi.org/10.1016/j.molcel.2020.09.020
6XOXB1PeptideGlucagonGLP-1Homo sapiensOrforglipron-chim(NtGi1-Gs)/β1/γ23.12020-11-18doi.org/10.1073/pnas.2014879117
6XOX (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOrforglipron-3.12020-11-18doi.org/10.1073/pnas.2014879117
7LCIB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/β1/γ22.92021-01-20doi.org/10.1016/j.str.2021.04.008
7LCI (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensDanuglipron-2.92021-01-20doi.org/10.1016/j.str.2021.04.008
7LCJB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--2.822021-01-20doi.org/10.1016/j.str.2021.04.008
7LCKB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--3.242021-01-20doi.org/10.1016/j.str.2021.04.008
7E14B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 156022738Gs/β1/γ22.92021-07-07doi.org/10.1038/s41467-021-24058-z
7E14 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 1560227382.92021-07-07doi.org/10.1038/s41467-021-24058-z
7DUQB1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 156022738Gs/β1/γ22.52021-07-14doi.org/10.1038/s41467-021-24058-z
7DUQ (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 1560227382.52021-07-14doi.org/10.1038/s41467-021-24058-z
7KI0B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-Gs/β1/γ22.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7KI0 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-2.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7KI1B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-Gs/β1/γ22.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7KI1 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-2.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7DURB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/β1/γ23.32021-08-11doi.org/10.1038/s41467-021-24058-z
7DUR (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-PubChem 1560227383.32021-08-11doi.org/10.1038/s41467-021-24058-z
7EVMB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/β1/γ22.52021-08-11doi.org/10.1038/s41467-021-24058-z
7EVM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-PubChem 1560227382.52021-08-11doi.org/10.1038/s41467-021-24058-z
7RTBB1PeptideGlucagonGLP-1Homo sapiensPeptide-19-Gs/β1/γ22.142021-10-06doi.org/10.1016/j.bbrc.2021.09.016
7RTB (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-19-2.142021-10-06doi.org/10.1016/j.bbrc.2021.09.016
7S1MB1PeptideGlucagonGLP-1Homo sapiensExendin-4-D-Ala-Gs/β1/γ22.412022-01-05doi.org/10.1038/s41589-021-00945-w
7S1M (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-4-D-Ala-2.412022-01-05doi.org/10.1038/s41589-021-00945-w
7S3IB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ22.512022-01-05doi.org/10.1038/s41589-021-00945-w
7S3I (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--2.512022-01-05doi.org/10.1038/s41589-021-00945-w
7LLLB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/β1/γ23.72022-01-12doi.org/10.1038/s41467-021-27760-0
7LLL (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-4-3.72022-01-12doi.org/10.1038/s41467-021-27760-0
7LLYB1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-Gs/β1/γ23.32022-01-12doi.org/10.1038/s41467-021-27760-0
7LLY (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-3.32022-01-12doi.org/10.1038/s41467-021-27760-0
7FIMB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-Gs/β1/γ23.42022-03-02doi.org/10.1038/s41467-022-28683-0
7FIM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide-3.42022-03-02doi.org/10.1038/s41467-022-28683-0
7VBIB1PeptideGlucagonGLP-1Homo sapiensTirzepatide (non-acylated)-Gs/β1/γ232022-03-02doi.org/10.1038/s41467-022-28683-0
7VBI (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide (non-acylated)-32022-03-02doi.org/10.1038/s41467-022-28683-0
7VBHB1PeptideGlucagonGLP-1Homo sapiensPeptide-20-Gs/β1/γ232022-04-06doi.org/10.1038/s41467-022-28683-0
7VBH (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-20-32022-04-06doi.org/10.1038/s41467-022-28683-0
7RG9B1PeptideGlucagonGLP-1Homo sapiens--chim(NtGi1-Gs)/β1/γ23.22022-04-13doi.org/10.1073/pnas.2116506119
7RG9 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.22022-04-13doi.org/10.1073/pnas.2116506119
7RGPB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-chim(NtGi1-Gs)/β1/γ22.92022-04-13doi.org/10.1073/pnas.2116506119
7RGP (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide-2.92022-04-13doi.org/10.1073/pnas.2116506119
7S15B1PeptideGlucagonGLP-1Homo sapiensPubChem 134611223--3.82022-06-08doi.org/10.1021/acs.jmedchem.1c01856
7X8RB1PeptideGlucagonGLP-1Homo sapiensBOC5-Gs/β1/γ22.612022-06-29doi.org/10.1073/pnas.2200155119
7X8R (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensBOC5-2.612022-06-29doi.org/10.1073/pnas.2200155119
7X8SB1PeptideGlucagonGLP-1Homo sapiensWB4-24-Gs/β1/γ23.092022-06-29doi.org/10.1073/pnas.2200155119
7X8S (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensWB4-24-3.092022-06-29doi.org/10.1073/pnas.2200155119
8JIPB1PeptideGlucagonGLP-1Homo sapiensMEDI0382-chim(NtGi1-Gs)/β1/γ22.852023-09-06doi.org/10.1073/pnas.2303696120
8JIP (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensMEDI0382-2.852023-09-06doi.org/10.1073/pnas.2303696120
8JIRB1PeptideGlucagonGLP-1Homo sapiensSAR425899-chim(NtGi1-Gs)/β1/γ22.572023-09-06doi.org/10.1073/pnas.2303696120
8JIR (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensSAR425899-2.572023-09-06doi.org/10.1073/pnas.2303696120
8JISB1PeptideGlucagonGLP-1Homo sapiensPeptide-15-chim(NtGi1-Gs)/β1/γ22.462023-11-08doi.org/10.1073/pnas.2303696120
8JIS (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-15-2.462023-11-08doi.org/10.1073/pnas.2303696120
8YW3B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-Gs/β1/γ22.682024-09-18doi.org/10.1038/s41421-024-00700-0
8YW3 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-2.682024-09-18doi.org/10.1038/s41421-024-00700-0
9J1PB1PeptideGlucagonGLP-1Homo sapiensg1:Ox-chim(NtGi1-Gs)/β1/γ22.992025-02-26doi.org/10.1021/jacs.4c12808
9J1P (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensg1:Ox-2.992025-02-26doi.org/10.1021/jacs.4c12808
8WG7B1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ22.542024-03-06doi.org/10.1038/s41421-024-00649-0
8WG7 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--2.542024-03-06doi.org/10.1038/s41421-024-00649-0
9IVMB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)LSN3318839chim(NtGi1-Gs)/β2/γ23.222024-11-13doi.org/10.1016/j.apsb.2024.09.002
9IVM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)LSN33188393.222024-11-13doi.org/10.1016/j.apsb.2024.09.002
9IVGB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ232024-11-27doi.org/10.1016/j.apsb.2024.09.002
9IVG (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)-32024-11-27doi.org/10.1016/j.apsb.2024.09.002
9EBNB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ23.442025-03-26doi.org/10.1073/pnas.2407574122
9EBN (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.442025-03-26doi.org/10.1073/pnas.2407574122
9EBOB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (ACPC18)-Gs/β1/γ23.132025-03-26doi.org/10.1073/pnas.2407574122
9EBO (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (ACPC18)-3.132025-03-26doi.org/10.1073/pnas.2407574122
9EBQB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ23.162025-03-26doi.org/10.1073/pnas.2407574122
9EBQ (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.162025-03-26doi.org/10.1073/pnas.2407574122
8YWFB1PeptideGlucagonGLP-1Homo sapiensRetatrutide-chim(NtGi1-Gs)/β1/γ22.742025-04-16To be published
8YWF (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-2.742025-04-16To be published
9BYOB1PeptideGlucagonGLP-1Homo sapiensExendin-3-Gs/β1/γ22.312025-06-11To be published
9BYO (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-3-2.312025-06-11To be published
9C0KB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/β1/γ22.722025-06-11To be published
9C0K (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-4-2.722025-06-11To be published
9E2AB1PeptideGlucagonGLP-1Homo sapiensGLP-1-Gs/β1/γ23.32025-10-29To be published
9E2A (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1-3.32025-10-29To be published




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