psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:G5	L:L:H1	7.94	No	Yes	0	0	0
2	L:L:H1	R:R:Q234	7.42	Yes	Yes	0	0	7
3	L:L:H1	R:R:V237	9.69	Yes	No	0	0	6
4	L:L:H1	R:R:W306	6.35	Yes	Yes	0	0	6
5	L:L:?2	L:L:K15	12.01	Yes	No	0	0	0
6	L:L:?2	R:R:L142	13.1	Yes	No	0	0	3
7	L:L:?2	R:R:Y145	6.66	Yes	Yes	2	0	5
8	L:L:?2	R:R:I146	8.1	Yes	No	0	0	4
9	L:L:?2	R:R:T149	4.18	Yes	No	2	0	7
10	L:L:?2	R:R:V150	4.23	Yes	No	0	0	5
11	L:L:?2	R:R:A153	5.96	Yes	No	0	0	6
12	L:L:?2	R:R:L154	3.93	Yes	No	0	0	5
13	L:L:?2	R:R:K202	6.67	Yes	No	0	0	4
14	L:L:S3	R:R:E387	5.75	No	No	0	0	8
15	L:L:S3	R:R:L388	9.01	No	Yes	0	0	7
16	L:L:Q4	R:R:Y148	16.91	Yes	Yes	2	0	7
17	L:L:Q4	R:R:Y152	9.02	Yes	Yes	2	0	7
18	L:L:Q4	R:R:V194	10.03	Yes	No	2	0	7
19	L:L:Q4	R:R:K197	4.07	Yes	Yes	0	0	6
20	L:L:Q4	R:R:L388	5.32	Yes	Yes	2	0	7
21	L:L:T6	R:R:D372	4.34	No	Yes	0	0	5
22	L:L:T6	R:R:L384	7.37	No	No	0	0	5
23	L:L:F7	R:R:L141	3.65	Yes	No	0	0	5
24	L:L:F7	R:R:L144	3.65	Yes	No	0	0	6
25	L:L:F7	R:R:Y148	11.35	Yes	Yes	2	0	7
26	L:L:F7	R:R:L388	4.87	Yes	Yes	2	0	7
27	L:L:T8	R:R:K197	9.01	No	Yes	0	0	6
28	L:L:S9	R:R:N300	7.45	No	No	0	0	6
29	L:L:D10	R:R:R380	9.53	No	No	0	0	5
30	L:L:S12	R:R:T298	6.4	No	No	1	0	5
31	L:L:S12	R:R:R299	10.54	No	Yes	1	0	4
32	L:L:Q14	R:R:L141	6.65	No	No	0	0	5
33	L:L:E16	R:R:S31	4.31	No	No	0	0	4
34	L:L:E16	R:R:Y205	13.47	No	No	1	0	3
35	L:L:E16	R:R:R299	11.63	No	Yes	1	0	4
36	L:L:A19	R:R:Q211	4.55	No	No	0	0	4
37	L:L:Q21	R:R:W91	26.29	No	No	0	0	4
38	L:L:F23	L:L:W26	5.01	Yes	No	3	0	0
39	L:L:F23	L:L:L27	4.87	Yes	No	3	0	0
40	L:L:F23	R:R:L32	4.87	Yes	No	0	0	4
41	L:L:F23	R:R:V36	3.93	Yes	No	3	0	2
42	L:L:F23	R:R:W39	6.01	Yes	Yes	3	0	5
43	L:L:F23	R:R:D215	9.55	Yes	No	3	0	3
44	L:L:I24	R:R:P90	5.08	No	Yes	0	0	4
45	L:L:W26	R:R:D215	4.47	No	No	3	0	3
46	L:L:L27	R:R:W39	12.53	No	Yes	3	0	5
47	L:L:L27	R:R:E68	6.63	No	No	0	0	4
48	L:L:K28	R:R:Y69	23.89	No	Yes	0	0	6
49	L:L:G30	R:R:E68	4.91	No	No	0	0	4
50	R:R:P90	R:R:V30	7.07	Yes	No	0	4	2
51	R:R:L32	R:R:T35	4.42	No	No	0	4	5
52	R:R:L32	R:R:W214	4.56	No	Yes	0	4	1
53	R:R:W214	R:R:W33	7.5	Yes	No	0	1	3
54	R:R:P90	R:R:T35	6.99	Yes	No	0	4	5
55	R:R:R40	R:R:V36	9.15	Yes	No	0	2	2
56	R:R:D215	R:R:V36	4.38	No	No	3	3	2
57	R:R:Q37	R:R:R40	4.67	No	Yes	0	4	2
58	R:R:E41	R:R:Q37	12.74	No	No	0	4	4
59	R:R:K38	R:R:Y88	22.69	No	No	0	4	5
60	R:R:R40	R:R:W39	7	Yes	Yes	0	2	5
61	R:R:R43	R:R:W39	14.99	No	Yes	0	4	5
62	R:R:G216	R:R:R40	4.5	No	Yes	0	2	2
63	R:R:C71	R:R:Y42	6.72	Yes	No	0	9	6
64	R:R:P86	R:R:Y42	4.17	Yes	No	0	8	6
65	R:R:W87	R:R:Y42	8.68	No	No	0	3	6
66	R:R:F66	R:R:R43	7.48	Yes	No	0	7	4
67	R:R:C46	R:R:F66	9.78	No	Yes	7	8	7
68	R:R:C46	R:R:C71	5.46	No	Yes	7	8	9
69	R:R:Q47	R:R:R48	14.02	No	No	0	3	4
70	R:R:R48	R:R:T51	10.35	No	No	0	4	4
71	R:R:E52	R:R:S49	4.31	No	No	0	2	2
72	R:R:R64	R:R:S49	5.27	Yes	No	0	4	2
73	R:R:L50	R:R:R64	14.58	No	Yes	0	4	4
74	R:R:F66	R:R:L50	4.87	Yes	No	0	7	4
75	R:R:D53	R:R:R64	7.15	No	Yes	0	3	4
76	R:R:P54	R:R:P55	7.79	No	No	0	2	1
77	R:R:D59	R:R:P56	4.83	No	No	0	3	1
78	R:R:F61	R:R:P56	4.33	Yes	No	0	3	1
79	R:R:L60	R:R:T58	5.9	No	No	0	1	1
80	R:R:F61	R:R:T58	6.49	Yes	No	0	3	1
81	R:R:F61	R:R:G75	4.52	Yes	No	0	3	7
82	R:R:F61	R:R:P77	14.45	Yes	No	0	3	4
83	R:R:C62	R:R:R102	9.75	No	Yes	8	9	8
84	R:R:C104	R:R:C62	7.28	No	No	8	9	9
85	R:R:N63	R:R:T65	5.85	No	No	0	4	5
86	R:R:P73	R:R:R64	18.74	No	Yes	0	5	4
87	R:R:C71	R:R:F66	6.98	Yes	Yes	7	9	7
88	R:R:L123	R:R:Y69	10.55	No	Yes	0	5	6
89	R:R:S124	R:R:Y69	11.45	No	Yes	0	5	6
90	R:R:C71	R:R:P73	3.77	Yes	No	0	9	5
91	R:R:G75	R:R:W72	5.63	No	Yes	0	7	9
92	R:R:V81	R:R:W72	11.03	No	Yes	0	6	9
93	R:R:V83	R:R:W72	6.13	No	Yes	0	5	9
94	R:R:R102	R:R:W72	43.98	Yes	Yes	0	8	9
95	R:R:D74	R:R:G75	5.03	No	No	0	3	7
96	R:R:D74	R:R:V81	7.3	No	No	0	3	6
97	R:R:E76	R:R:S79	7.19	No	No	0	1	5
98	R:R:E76	R:R:V81	11.41	No	No	0	1	6
99	R:R:F80	R:R:Y101	6.19	No	No	0	4	5
100	R:R:F103	R:R:F80	8.57	No	No	0	4	4
101	R:R:H99	R:R:N82	16.58	No	No	0	4	4
102	R:R:N82	R:R:Y101	5.81	No	No	0	4	5
103	R:R:V100	R:R:V83	6.41	No	No	0	7	5
104	R:R:S84	R:R:W87	7.41	No	No	0	4	3
105	R:R:H99	R:R:S84	6.97	No	No	0	4	4
106	R:R:C85	R:R:P86	3.77	No	Yes	0	9	8
107	R:R:C126	R:R:C85	5.46	No	No	0	9	9
108	R:R:L89	R:R:P86	4.93	No	Yes	0	5	8
109	R:R:A92	R:R:L89	4.73	No	No	0	5	5
110	R:R:E127	R:R:W91	10.9	No	No	0	2	4
111	R:R:A92	R:R:V95	5.09	No	No	0	5	5
112	R:R:P96	R:R:V95	5.3	No	No	0	3	5
113	R:R:D122	R:R:V100	7.3	No	No	0	7	7
114	R:R:L123	R:R:V100	4.47	No	No	0	5	7
115	R:R:C104	R:R:R102	4.18	No	Yes	8	9	8
116	R:R:R102	R:R:W110	4	Yes	No	0	8	9
117	R:R:R102	R:R:W120	37.99	Yes	No	0	8	5
118	R:R:E107	R:R:T105	7.06	No	No	0	5	4
119	R:R:L111	R:R:T105	4.42	No	No	0	4	4
120	R:R:E107	R:R:L109	6.63	No	No	0	5	5
121	R:R:L111	R:R:P119	6.57	No	No	0	4	6
122	R:R:L118	R:R:S117	4.5	No	No	0	4	7
123	R:R:L118	R:R:W120	12.53	No	No	0	4	5
124	R:R:P119	R:R:W120	9.46	No	No	0	6	5
125	R:R:E138	R:R:E139	3.81	No	No	0	2	2
126	R:R:E138	R:R:Q140	5.1	No	No	0	2	4
127	R:R:F381	R:R:Q140	11.71	No	No	0	4	4
128	R:R:F143	R:R:I147	5.02	No	No	0	4	6
129	R:R:F381	R:R:L144	6.09	No	No	0	4	6
130	R:R:F385	R:R:L144	3.65	No	No	0	6	6
131	R:R:Y145	R:R:Y148	3.97	Yes	Yes	2	5	7
132	R:R:T149	R:R:Y145	11.24	No	Yes	2	7	5
133	R:R:D198	R:R:Y145	13.79	No	Yes	0	7	5
134	R:R:I147	R:R:S389	4.64	No	No	0	6	5
135	R:R:T149	R:R:Y148	3.75	No	Yes	2	7	7
136	R:R:Y148	R:R:Y152	3.97	Yes	Yes	2	7	7
137	R:R:V194	R:R:Y148	5.05	No	Yes	2	7	7
138	R:R:L388	R:R:Y148	4.69	Yes	Yes	2	7	7
139	R:R:G151	R:R:V150	3.68	No	No	0	8	5
140	R:R:G151	R:R:S392	3.71	No	No	2	8	9
141	R:R:F393	R:R:G151	9.03	No	No	2	7	8
142	R:R:R190	R:R:Y152	9.26	Yes	Yes	0	8	7
143	R:R:V194	R:R:Y152	10.09	No	Yes	2	7	7
144	R:R:S392	R:R:Y152	5.09	No	Yes	2	9	7
145	R:R:G395	R:R:S155	3.71	No	No	0	9	9
146	R:R:F156	R:R:V160	3.93	Yes	No	0	7	3
147	R:R:F156	R:R:I188	5.02	Yes	No	0	7	7
148	R:R:F156	R:R:L192	4.87	Yes	No	0	7	3
149	R:R:F184	R:R:L159	4.87	Yes	Yes	0	8	9
150	R:R:F187	R:R:L159	3.65	Yes	Yes	0	8	9
151	R:R:F404	R:R:I161	3.77	No	No	0	8	4
152	R:R:F184	R:R:S163	3.96	Yes	No	0	8	6
153	R:R:F413	R:R:I165	6.28	No	No	0	5	8
154	R:R:L166	R:R:N177	10.98	Yes	Yes	0	8	9
155	R:R:L166	R:R:L181	6.92	Yes	No	0	8	6
156	R:R:F184	R:R:L166	3.65	Yes	Yes	0	8	8
157	R:R:L167	R:R:L181	5.54	No	No	0	3	6
158	R:R:F169	R:R:L172	3.65	Yes	No	0	7	9
159	R:R:E412	R:R:F169	22.15	No	Yes	0	8	7
160	R:R:F169	R:R:F413	10.72	Yes	No	0	7	5
161	R:R:H173	R:R:R170	4.51	No	No	0	7	8
162	R:R:E412	R:R:H171	12.31	No	No	0	8	7
163	R:R:H173	R:R:Y178	13.07	No	No	0	7	6
164	R:R:C174	R:R:R176	4.18	No	Yes	4	8	9
165	R:R:C174	R:R:N177	4.72	No	Yes	4	8	9
166	R:R:T175	R:R:Y250	4.99	No	No	0	7	8
167	R:R:E262	R:R:T175	5.64	No	No	0	6	7
168	R:R:N177	R:R:R176	7.23	Yes	Yes	4	9	9
169	R:R:H180	R:R:R176	4.51	No	Yes	4	9	9
170	R:R:E408	R:R:R176	10.47	No	Yes	0	9	9
171	R:R:H180	R:R:N177	6.38	No	Yes	4	9	9
172	R:R:F266	R:R:Y178	7.22	No	No	0	6	6
173	R:R:E247	R:R:I179	4.1	No	No	0	9	8
174	R:R:E247	R:R:H180	11.08	No	No	0	9	9
175	R:R:N182	R:R:W243	16.95	No	Yes	0	9	9
176	R:R:F187	R:R:L183	6.09	Yes	No	0	8	9
177	R:R:L183	R:R:L244	4.15	No	No	0	9	9
178	R:R:F184	R:R:V398	3.93	Yes	No	0	8	9
179	R:R:N240	R:R:S186	5.96	No	No	0	9	9
180	R:R:S186	R:R:W243	7.41	No	Yes	0	9	9
181	R:R:F187	R:R:N240	13.29	Yes	No	0	8	9
182	R:R:F187	R:R:Q394	10.54	Yes	Yes	0	8	9
183	R:R:F187	R:R:G395	9.03	Yes	No	0	8	9
184	R:R:F187	R:R:V398	5.24	Yes	No	0	8	9
185	R:R:C236	R:R:L189	6.35	No	No	0	5	7
186	R:R:R190	R:R:V237	11.77	Yes	No	0	8	6
187	R:R:N240	R:R:R190	9.64	No	Yes	0	9	8
188	R:R:R190	R:R:Y241	9.26	Yes	Yes	0	8	8
189	R:R:R190	R:R:T391	5.17	Yes	No	0	8	6
190	R:R:C236	R:R:S193	6.89	No	No	0	5	6
191	R:R:D198	R:R:K197	4.15	No	Yes	0	7	6
192	R:R:F230	R:R:K197	3.72	Yes	Yes	0	5	6
193	R:R:K197	R:R:M233	7.2	Yes	No	0	6	6
194	R:R:A200	R:R:W203	3.89	No	No	0	4	3
195	R:R:F230	R:R:L201	3.65	Yes	No	0	5	7
196	R:R:W203	R:R:Y220	7.72	No	Yes	0	3	3
197	R:R:M204	R:R:Y220	9.58	Yes	Yes	1	3	3
198	R:R:M204	R:R:Q221	12.23	Yes	Yes	1	3	4
199	R:R:C226	R:R:M204	4.86	No	Yes	1	9	3
200	R:R:C296	R:R:M204	6.48	No	Yes	1	9	3
201	R:R:Q221	R:R:Y205	5.64	Yes	No	1	4	3
202	R:R:R299	R:R:Y205	5.14	Yes	No	1	4	3
203	R:R:A209	R:R:T207	5.03	No	No	0	1	3
204	R:R:Q210	R:R:Q211	3.84	Yes	No	0	4	4
205	R:R:Q210	R:R:W214	9.86	Yes	Yes	1	4	1
206	R:R:Q210	R:R:S219	10.11	Yes	No	1	4	5
207	R:R:Q210	R:R:Q221	8.96	Yes	Yes	1	4	4
208	R:R:Q213	R:R:S219	4.33	No	No	0	4	5
209	R:R:S219	R:R:W214	9.88	No	Yes	1	5	1
210	R:R:Q221	R:R:W214	15.33	Yes	Yes	1	4	1
211	R:R:D222	R:R:L218	6.79	No	No	0	6	3
212	R:R:S223	R:R:Y220	10.17	No	Yes	0	4	3
213	R:R:S225	R:R:Y220	5.09	No	Yes	0	3	3
214	R:R:C226	R:R:Y220	9.41	No	Yes	1	9	3
215	R:R:L224	R:R:L228	4.15	No	No	0	3	4
216	R:R:C226	R:R:C296	7.28	No	No	1	9	9
217	R:R:D293	R:R:R227	11.91	No	No	9	7	8
218	R:R:R227	R:R:W297	12	No	Yes	9	8	8
219	R:R:F230	R:R:V229	5.24	Yes	No	0	5	7
220	R:R:F230	R:R:T298	7.78	Yes	No	0	5	5
221	R:R:M233	R:R:Q234	4.08	No	Yes	0	6	7
222	R:R:Q234	R:R:W284	13.14	Yes	Yes	5	7	8
223	R:R:I309	R:R:Q234	6.86	No	Yes	5	7	7
224	R:R:A239	R:R:Y235	4	No	Yes	10	8	9
225	R:R:W274	R:R:Y235	4.82	No	Yes	0	9	9
226	R:R:P277	R:R:Y235	4.17	Yes	Yes	10	9	9
227	R:R:L278	R:R:Y235	4.69	No	Yes	0	3	9
228	R:R:V281	R:R:Y235	3.79	No	Yes	0	6	9
229	R:R:A239	R:R:P277	3.74	No	Yes	10	8	9
230	R:R:I313	R:R:Y241	14.51	No	Yes	0	7	8
231	R:R:E364	R:R:Y241	6.73	No	Yes	0	8	8
232	R:R:V276	R:R:Y242	6.31	No	No	0	3	6
233	R:R:F280	R:R:Y242	7.22	No	No	0	5	6
234	R:R:A316	R:R:Y242	5.34	No	No	0	7	6
235	R:R:V246	R:R:W243	6.13	No	Yes	0	8	9
236	R:R:G273	R:R:W243	8.44	No	Yes	0	9	9
237	R:R:W243	R:R:W274	21.56	Yes	No	0	9	9
238	R:R:L244	R:R:Q394	6.65	No	Yes	0	9	9
239	R:R:V246	R:R:Y269	3.79	No	Yes	0	8	7
240	R:R:E247	R:R:L359	11.93	No	No	0	9	9
241	R:R:V249	R:R:Y269	3.79	No	Yes	0	6	7
242	R:R:L254	R:R:Y250	11.72	No	No	0	8	8
243	R:R:Y250	R:R:Y269	8.94	No	Yes	0	8	7
244	R:R:L251	R:R:V327	4.47	No	No	0	9	9
245	R:R:A256	R:R:Y252	5.34	No	No	0	6	8
246	R:R:R326	R:R:Y252	10.29	No	No	0	8	8
247	R:R:F257	R:R:T253	5.19	No	No	0	5	7
248	R:R:A256	R:R:F257	4.16	No	No	0	6	5
249	R:R:E262	R:R:V259	5.7	No	No	0	6	6
250	R:R:I265	R:R:Y269	8.46	No	Yes	0	5	7
251	R:R:F266	R:R:V270	6.55	No	No	0	6	5
252	R:R:I272	R:R:V276	4.61	Yes	No	0	6	3
253	R:R:F280	R:R:P312	15.89	No	No	0	5	8
254	R:R:K288	R:R:W284	13.92	No	Yes	0	8	8
255	R:R:I308	R:R:W284	7.05	No	Yes	0	8	8
256	R:R:I309	R:R:W284	7.05	No	Yes	5	7	8
257	R:R:V287	R:R:Y305	8.83	No	Yes	0	4	4
258	R:R:E292	R:R:K288	14.85	Yes	No	0	6	8
259	R:R:K288	R:R:W297	12.76	No	Yes	0	8	8
260	R:R:D293	R:R:Y289	4.6	No	No	0	7	3
261	R:R:L290	R:R:Y291	7.03	No	No	0	3	3
262	R:R:Y291	R:R:Y305	7.94	No	Yes	0	3	4
263	R:R:E292	R:R:S301	4.31	Yes	No	0	6	3
264	R:R:E292	R:R:N302	3.94	Yes	No	11	6	5
265	R:R:E292	R:R:Y305	6.73	Yes	Yes	11	6	4
266	R:R:D293	R:R:W297	8.93	No	Yes	9	7	8
267	R:R:E294	R:R:R299	16.28	No	Yes	0	4	4
268	R:R:G295	R:R:R299	4.5	No	Yes	0	4	4
269	R:R:R299	R:R:T298	3.88	Yes	No	1	4	5
270	R:R:N300	R:R:W306	25.99	No	Yes	0	6	6
271	R:R:N302	R:R:N304	5.45	No	No	0	5	3
272	R:R:N302	R:R:Y305	16.28	No	Yes	11	5	4
273	R:R:R310	R:R:W306	20.99	Yes	Yes	6	6	6
274	R:R:D372	R:R:W306	4.47	Yes	Yes	6	5	6
275	R:R:L307	R:R:R310	4.86	No	Yes	0	7	6
276	R:R:L307	R:R:L311	4.15	No	No	0	7	4
277	R:R:M371	R:R:R310	3.72	No	Yes	0	7	6
278	R:R:D372	R:R:R310	4.76	Yes	Yes	6	5	6
279	R:R:F315	R:R:V319	5.24	No	No	0	4	6
280	R:R:L360	R:R:N320	15.1	No	No	0	9	9
281	R:R:F321	R:R:V325	5.24	No	No	0	6	5
282	R:R:F321	R:R:V365	3.93	No	No	0	6	6
283	R:R:F324	R:R:I328	6.28	Yes	No	0	9	7
284	R:R:F324	R:R:L356	6.09	Yes	No	0	9	9
285	R:R:F324	R:R:T362	12.97	Yes	No	0	9	7
286	R:R:I328	R:R:T353	6.08	No	No	0	7	9
287	R:R:M340	R:R:N338	7.01	No	No	0	5	6
288	R:R:D344	R:R:K342	17.97	No	No	0	7	5
289	R:R:K351	R:R:R348	7.43	No	No	0	8	8
290	R:R:R348	R:R:S352	5.27	No	No	0	8	9
291	R:R:L401	R:R:T355	7.37	No	No	0	8	8
292	R:R:L356	R:R:L360	5.54	No	No	0	9	9
293	R:R:I357	R:R:T362	6.08	No	No	0	8	7
294	R:R:L359	R:R:Y402	17.58	No	No	0	9	8
295	R:R:E364	R:R:H363	4.92	No	No	0	8	8
296	R:R:F390	R:R:H363	7.92	No	No	0	6	8
297	R:R:H363	R:R:Q394	9.89	No	Yes	0	8	9
298	R:R:E364	R:R:E387	12.69	No	No	0	8	8
299	R:R:F367	R:R:T386	3.89	Yes	No	0	7	4
300	R:R:H374	R:R:V370	5.54	No	No	12	3	5
301	R:R:L379	R:R:V370	4.47	No	No	12	3	5
302	R:R:D372	R:R:R380	5.96	Yes	No	0	5	5
303	R:R:E373	R:R:H374	16	No	No	0	4	3
304	R:R:H374	R:R:L379	3.86	No	No	12	3	3
305	R:R:L379	R:R:R376	8.5	No	No	0	3	5
306	R:R:E387	R:R:K383	12.15	No	No	0	8	7
307	R:R:F385	R:R:S389	5.28	No	No	0	6	5
308	R:R:F390	R:R:T386	3.89	No	No	0	6	4
309	R:R:F393	R:R:S392	5.28	No	No	2	7	9
310	R:R:I400	R:R:L396	4.28	No	No	0	6	7
311	R:R:C403	R:R:F404	4.19	No	No	0	9	8
312	R:R:E408	R:R:N406	17.09	No	No	0	9	9
313	R:R:N406	R:R:V409	5.91	No	No	0	9	9
314	R:R:E412	R:R:K415	8.1	No	No	0	8	7
315	R:R:K415	R:R:R419	7.43	No	No	0	7	7
316	R:R:E418	R:R:W417	4.36	No	No	0	4	5
317	R:R:L224	R:R:R227	3.64	No	No	0	3	8
318	R:R:I317	R:R:Y241	3.63	No	Yes	0	7	8
319	R:R:I323	R:R:Y252	3.63	No	No	0	8	8
320	R:R:A162	R:R:C403	3.61	No	No	0	9	9
321	R:R:G273	R:R:I272	3.53	No	Yes	0	9	6
322	R:R:P277	R:R:V276	3.53	Yes	No	0	9	3
323	R:R:P283	R:R:V282	3.53	No	No	0	5	3
324	L:L:I24	R:R:W91	3.52	No	No	0	0	4
325	R:R:I265	R:R:W264	3.52	No	No	0	5	5
326	R:R:L401	R:R:Y402	3.52	No	No	0	8	8
327	R:R:D67	R:R:Y69	3.45	No	Yes	0	9	6
328	R:R:D122	R:R:Y101	3.45	No	No	0	7	5
329	R:R:L231	R:R:W297	3.42	No	Yes	0	5	8
330	R:R:I357	R:R:P358	3.39	No	No	0	8	9
331	R:R:K113	R:R:P119	3.35	No	No	0	4	6
332	R:R:M397	R:R:P358	3.35	No	No	0	5	9
333	R:R:G361	R:R:Q394	3.29	No	Yes	0	9	9
334	R:R:L401	R:R:P358	3.28	No	No	0	8	9
335	R:R:E34	R:R:W33	3.27	No	No	0	4	3
336	R:R:C403	R:R:I165	3.27	No	No	0	9	8
337	R:R:S352	R:R:V331	3.23	No	No	0	9	8
338	R:R:C236	R:R:L232	3.17	No	No	0	5	5
339	R:R:A399	R:R:L159	3.15	No	Yes	0	8	9
340	R:R:A316	R:R:L245	3.15	No	No	0	7	8
341	R:R:M233	R:R:S193	3.07	No	No	0	6	6
342	R:R:I196	R:R:V229	3.07	No	No	0	5	7
343	L:L:K13	L:L:S9	3.06	No	No	0	0	0
344	R:R:K202	R:R:S206	3.06	No	No	0	4	4
345	R:R:K336	R:R:V332	3.04	No	No	0	6	6
346	R:R:A209	R:R:Q213	3.03	No	No	0	1	4
347	R:R:L245	R:R:V319	2.98	No	No	0	8	6
348	R:R:L356	R:R:V327	2.98	No	No	0	9	9
349	R:R:L349	R:R:V332	2.98	No	No	0	9	6
350	R:R:L349	R:R:T353	2.95	No	No	0	9	9
351	R:R:I330	R:R:K334	2.91	No	No	0	9	9
352	R:R:I345	R:R:K336	2.91	Yes	No	0	5	6
353	R:R:I188	R:R:L159	2.85	No	Yes	0	7	9
354	R:R:I330	R:R:L255	2.85	No	No	0	9	8
355	R:R:I265	R:R:L260	2.85	No	No	0	5	7
356	R:R:I272	R:R:L268	2.85	Yes	No	0	6	2
357	R:R:I323	R:R:N320	2.83	No	No	0	8	9
358	L:L:K15	L:L:L11	2.82	No	No	0	0	0
359	R:R:G285	R:R:W284	2.81	No	Yes	0	5	8
360	R:R:C329	R:R:R326	2.79	No	No	0	7	8
361	R:R:D114	R:R:K113	2.77	No	No	0	4	4
362	R:R:A191	R:R:F156	2.77	No	Yes	0	7	7
363	R:R:A162	R:R:F184	2.77	No	Yes	0	9	8
364	R:R:L166	R:R:L172	2.77	Yes	No	0	8	9
365	R:R:A238	R:R:F280	2.77	No	No	0	6	5
366	R:R:D372	R:R:M303	2.77	Yes	No	0	5	5
367	R:R:A368	R:R:F369	2.77	No	No	0	6	4
368	R:R:E41	R:R:K38	2.7	No	No	0	4	4
369	R:R:L111	R:R:Q112	2.66	No	No	0	4	3
370	R:R:L217	R:R:Q213	2.66	No	No	0	4	4
371	R:R:F169	R:R:S416	2.64	Yes	No	0	7	5
372	R:R:F367	R:R:V370	2.62	Yes	No	0	7	5
373	R:R:F266	R:R:T175	2.59	No	No	0	6	7
374	R:R:F367	R:R:I366	2.51	Yes	No	0	7	6
375	R:R:F367	R:R:I382	2.51	Yes	No	0	7	4
376	R:R:F404	R:R:I400	2.51	No	No	0	8	6
377	R:R:S261	R:R:W264	2.47	No	No	0	7	5
378	R:R:L335	R:R:R348	2.43	No	No	0	8	8
379	R:R:E52	R:R:R48	2.33	No	No	0	2	4
380	R:R:D222	R:R:W214	2.23	No	Yes	0	6	1
381	R:R:F321	R:R:F324	2.14	No	Yes	0	6	9
382	R:R:F195	R:R:Y152	2.06	No	Yes	0	7	7
383	R:R:G275	R:R:P277	2.03	No	Yes	0	6	9
384	R:R:R421	R:R:W420	2	No	No	0	4	4
385	R:R:P55	R:R:P56	1.95	No	No	0	1	1
386	R:R:A106	R:R:G78	1.95	No	No	0	1	7
387	L:L:A20	R:R:P90	1.87	No	Yes	0	0	4
388	R:R:A70	R:R:P86	1.87	No	Yes	0	5	8
389	R:R:A158	R:R:A399	1.79	No	No	0	7	8
390	R:R:G248	R:R:I323	1.76	No	No	0	8	8
391	R:R:G318	R:R:I317	1.76	No	No	0	4	7
392	R:R:G108	R:R:L109	1.71	No	No	0	9	5
393	R:R:G168	R:R:L167	1.71	No	No	0	1	3
394	R:R:A57	R:R:T58	1.68	No	No	0	1	1
395	R:R:C341	R:R:I345	1.64	No	Yes	0	4	5
396	R:R:S93	R:R:S94	1.63	No	No	0	3	4
397	R:R:A368	R:R:I317	1.62	No	No	0	6	7
398	R:R:G98	R:R:H99	1.59	No	No	0	4	4
399	R:R:P96	R:R:Q97	1.58	No	No	0	3	4
400	R:R:I272	R:R:S271	1.55	Yes	No	0	6	3
401	R:R:A199	R:R:D198	1.54	No	No	0	3	7
402	R:R:I286	R:R:V282	1.54	No	No	0	4	3
403	R:R:I400	R:R:V405	1.54	No	No	0	6	6
404	R:R:G377	R:R:R376	1.5	No	No	0	4	5
405	R:R:L255	R:R:V327	1.49	No	No	0	8	9
406	R:R:L278	R:R:V282	1.49	No	No	0	3	3
407	R:R:Q45	R:R:S49	1.44	No	No	0	5	2
408	R:R:Q263	R:R:S261	1.44	No	No	0	5	7
409	R:R:I345	R:R:L335	1.43	Yes	No	0	5	8
410	R:R:I357	R:R:L354	1.43	No	No	0	8	8
411	R:R:L339	R:R:M340	1.41	No	No	0	7	5
412	R:R:K346	R:R:L349	1.41	No	No	0	6	9
413	R:R:D344	R:R:I345	1.4	No	Yes	0	7	5
414	L:L:D22	L:L:K18	1.38	No	No	0	0	0
415	R:R:A375	R:R:R380	1.38	No	No	0	4	5
416	L:L:E25	L:L:K28	1.35	No	No	0	0	0
417	R:R:D114	R:R:N115	1.35	No	No	0	4	4
418	R:R:N407	R:R:Q410	1.32	No	No	0	6	7
419	L:L:D22	L:L:Q21	1.31	No	No	0	0	0
420	R:R:A185	R:R:W274	1.3	No	No	0	3	9
421	R:R:R299	R:R:T29	1.29	Yes	No	0	4	2
422	R:R:F369	R:R:L314	1.22	No	No	0	4	4
423	R:R:E125	R:R:R121	1.16	No	No	0	5	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:H1	7.85	4	0	0
2	L:L:?2	7.20444	9	2	0
3	L:L:Q4	9.07	5	2	0
4	L:L:F7	5.88	4	2	0
5	L:L:F23	5.70667	6	3	0
6	R:R:W39	10.1325	4	3	5
7	R:R:R40	6.33	4	0	2
8	R:R:F61	7.4475	4	0	3
9	R:R:R64	11.435	4	0	4
10	R:R:F66	7.2775	4	7	7
11	R:R:Y69	12.335	4	0	6
12	R:R:C71	5.7325	4	7	9
13	R:R:W72	16.6925	4	0	9
14	R:R:P86	3.685	4	0	8
15	R:R:P90	5.2525	4	0	4
16	R:R:R102	19.98	5	8	8
17	R:R:Y145	8.915	4	2	5
18	R:R:Y148	7.09857	7	2	7
19	R:R:Y152	6.58167	6	2	7
20	R:R:F156	4.1475	4	0	7
21	R:R:L159	3.63	4	0	9
22	R:R:L166	6.08	4	0	8
23	R:R:F169	9.79	4	0	7
24	R:R:R176	6.5975	4	4	9
25	R:R:N177	7.3275	4	4	9
26	R:R:F184	3.836	5	0	8
27	R:R:F187	7.97333	6	0	8
28	R:R:R190	9.02	5	0	8
29	R:R:K197	5.63	5	0	6
30	R:R:M204	8.2875	4	1	3
31	R:R:Q210	8.1925	4	1	4
32	R:R:W214	8.22667	6	1	1
33	R:R:Y220	8.394	5	1	3
34	R:R:Q221	10.54	4	1	4
35	R:R:F230	5.0975	4	0	5
36	R:R:Q234	7.875	4	5	7
37	R:R:Y235	4.294	5	10	9
38	R:R:Y241	8.5325	4	0	8
39	R:R:W243	12.098	5	0	9
40	R:R:Y269	6.245	4	0	7
41	R:R:I272	3.135	4	0	6
42	R:R:P277	3.3675	4	10	9
43	R:R:W284	8.794	5	5	8
44	R:R:E292	7.4575	4	11	6
45	R:R:W297	9.2775	4	9	8
46	R:R:R299	7.60857	7	1	4
47	R:R:Y305	9.945	4	11	4
48	R:R:W306	14.45	4	6	6
49	R:R:R310	8.5825	4	6	6
50	R:R:F324	6.87	4	0	9
51	R:R:I345	1.845	4	0	5
52	R:R:F367	2.8825	4	0	7
53	R:R:D372	4.46	5	6	5
54	R:R:L388	5.9725	4	2	7
55	R:R:Q394	7.5925	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:H1	R:R:Q234	17.788	7.42	Yes	Yes	0	0	7
2	L:L:H1	R:R:V237	20.8498	9.69	Yes	No	0	0	6
3	L:L:H1	R:R:W306	13.12	6.35	Yes	Yes	0	0	6
4	R:R:Y148	R:R:Y152	16.8618	3.97	Yes	Yes	2	7	7
5	R:R:R190	R:R:Y152	88.4641	9.26	Yes	Yes	0	8	7
6	R:R:R190	R:R:V237	21.2982	11.77	Yes	No	0	8	6
7	R:R:K197	R:R:M233	17.0915	7.2	Yes	No	0	6	6
8	R:R:M233	R:R:Q234	15.511	4.08	No	Yes	0	6	7
9	L:L:Q4	R:R:K197	82.9067	4.07	Yes	Yes	0	0	6
10	L:L:Q4	R:R:Y152	70.0127	9.02	Yes	Yes	2	0	7
11	R:R:R190	R:R:Y241	11.9236	9.26	Yes	Yes	0	8	8
12	L:L:F7	R:R:L144	10.65	3.65	Yes	No	0	0	6
13	R:R:F230	R:R:K197	92.7187	3.72	Yes	Yes	0	5	6
14	R:R:F230	R:R:T298	91.197	7.78	Yes	No	0	5	5
15	R:R:R299	R:R:T298	90.1586	3.88	Yes	No	1	4	5
16	R:R:R299	R:R:Y205	87.4883	5.14	Yes	No	1	4	3
17	R:R:Q221	R:R:Y205	87.5581	5.64	Yes	No	1	4	3
18	R:R:Q221	R:R:W214	78.1817	15.33	Yes	Yes	1	4	1
19	R:R:L32	R:R:W214	73.8904	4.56	No	Yes	0	4	1
20	L:L:F23	R:R:L32	68.0481	4.87	Yes	No	0	0	4
21	L:L:F23	R:R:W39	59.2028	6.01	Yes	Yes	3	0	5
22	R:R:R43	R:R:W39	55.5952	14.99	No	Yes	0	4	5
23	R:R:F66	R:R:R43	54.9758	7.48	Yes	No	0	7	4
24	R:R:C71	R:R:F66	46.9171	6.98	Yes	Yes	7	9	7
25	R:R:C71	R:R:Y42	46.6102	6.72	Yes	No	0	9	6
26	R:R:W87	R:R:Y42	39.7699	8.68	No	No	0	3	6
27	R:R:S84	R:R:W87	39.0642	7.41	No	No	0	4	3
28	R:R:H99	R:R:S84	38.3548	6.97	No	No	0	4	4
29	R:R:H99	R:R:N82	36.925	16.58	No	No	0	4	4
30	R:R:N82	R:R:Y101	36.2046	5.81	No	No	0	4	5
31	R:R:D122	R:R:Y101	34.0213	3.45	No	No	0	7	5
32	R:R:D122	R:R:V100	33.2862	7.3	No	No	0	7	7
33	R:R:V100	R:R:V83	28.054	6.41	No	No	0	7	5
34	R:R:V83	R:R:W72	27.2894	6.13	No	Yes	0	5	9
35	R:R:R102	R:R:W72	14.5572	43.98	Yes	Yes	0	8	9
36	R:R:R102	R:R:W120	11.2271	37.99	Yes	No	0	8	5
37	R:R:N240	R:R:R190	100	9.64	No	Yes	0	9	8
38	R:R:F187	R:R:N240	93.4905	13.29	Yes	No	0	8	9
39	R:R:F187	R:R:L159	49.7161	3.65	Yes	Yes	0	8	9
40	R:R:F184	R:R:L159	46.0993	4.87	Yes	Yes	0	8	9
41	R:R:F187	R:R:V398	45.57	5.24	Yes	No	0	8	9
42	R:R:F184	R:R:V398	45.1216	3.93	Yes	No	0	8	9
43	R:R:A162	R:R:F184	11.6939	2.77	No	Yes	0	9	8
44	R:R:A162	R:R:C403	10.3982	3.61	No	No	0	9	9
45	R:R:F184	R:R:L166	79.0932	3.65	Yes	Yes	0	8	8
46	R:R:L166	R:R:L172	10.5839	2.77	Yes	No	0	8	9
47	R:R:L166	R:R:N177	65.8427	10.98	Yes	Yes	0	8	9
48	R:R:N240	R:R:S186	36.3865	5.96	No	No	0	9	9
49	R:R:S186	R:R:W243	35.6588	7.41	No	Yes	0	9	9
50	R:R:V246	R:R:W243	15.4467	6.13	No	Yes	0	8	9
51	R:R:V246	R:R:Y269	14.6197	3.79	No	Yes	0	8	7
52	R:R:H180	R:R:N177	58.5614	6.38	No	Yes	4	9	9
53	R:R:E247	R:R:H180	57.8226	11.08	No	No	0	9	9
54	R:R:Q234	R:R:W284	16.27	13.14	Yes	Yes	5	7	8
55	R:R:K288	R:R:W284	13.8184	13.92	No	Yes	0	8	8
56	R:R:G273	R:R:W243	11.0396	8.44	No	Yes	0	9	9
57	R:R:G273	R:R:I272	10.2034	3.53	No	Yes	0	9	6
58	R:R:E247	R:R:L359	55.4702	11.93	No	No	0	9	9
59	R:R:L359	R:R:Y402	54.2885	17.58	No	No	0	9	8
60	R:R:L401	R:R:Y402	53.1031	3.52	No	No	0	8	8
61	R:R:L401	R:R:P358	50.7213	3.28	No	No	0	8	9
62	R:R:I357	R:R:P358	48.3249	3.39	No	No	0	8	9
63	R:R:I357	R:R:T362	45.9137	6.08	No	No	0	8	7
64	R:R:F324	R:R:T362	44.7026	12.97	Yes	No	0	9	7
65	R:R:F324	R:R:L356	20.9931	6.09	Yes	No	0	9	9
66	R:R:L356	R:R:L360	13.2303	5.54	No	No	0	9	9
67	R:R:L360	R:R:N320	11.9236	15.1	No	No	0	9	9
68	R:R:I323	R:R:N320	10.6133	2.83	No	No	0	8	9
69	R:R:F324	R:R:I328	19.7085	6.28	Yes	No	0	9	7
70	R:R:I328	R:R:T353	18.4202	6.08	No	No	0	7	9
71	R:R:L349	R:R:T353	17.1283	2.95	No	No	0	9	9
72	R:R:L349	R:R:V332	14.5333	2.98	No	No	0	9	6
73	R:R:K336	R:R:V332	13.2303	3.04	No	No	0	6	6
74	R:R:I345	R:R:K336	11.9236	2.91	Yes	No	0	5	6
75	R:R:E364	R:R:H363	10.9	4.92	No	No	0	8	8
76	R:R:F390	R:R:H363	13.1182	7.92	No	No	0	6	8
77	R:R:F390	R:R:T386	11.9438	3.89	No	No	0	6	4
78	R:R:F367	R:R:T386	10.7658	3.89	Yes	No	0	7	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:H1	R:R:Q234	7.42	0	Yes	Yes	0	7	0	1
L:L:H1	R:R:V237	9.69	0	Yes	No	0	6	0	1
L:L:H1	R:R:W306	6.35	0	Yes	Yes	0	6	0	1
L:L:?2	R:R:L142	13.1	2	Yes	No	0	3	0	1
L:L:?2	R:R:Y145	6.66	2	Yes	Yes	0	5	0	1
L:L:?2	R:R:I146	8.1	2	Yes	No	0	4	0	1
L:L:?2	R:R:T149	4.18	2	Yes	No	0	7	0	1
L:L:?2	R:R:V150	4.23	2	Yes	No	0	5	0	1
L:L:?2	R:R:A153	5.96	2	Yes	No	0	6	0	1
L:L:?2	R:R:L154	3.93	2	Yes	No	0	5	0	1
L:L:?2	R:R:K202	6.67	2	Yes	No	0	4	0	1
L:L:S3	R:R:E387	5.75	0	No	No	0	8	0	1
L:L:S3	R:R:L388	9.01	0	No	Yes	0	7	0	1
L:L:Q4	R:R:Y148	16.91	2	Yes	Yes	0	7	0	1
L:L:Q4	R:R:Y152	9.02	2	Yes	Yes	0	7	0	1
L:L:Q4	R:R:V194	10.03	2	Yes	No	0	7	0	1
L:L:Q4	R:R:K197	4.07	2	Yes	Yes	0	6	0	1
L:L:Q4	R:R:L388	5.32	2	Yes	Yes	0	7	0	1
L:L:T6	R:R:D372	4.34	0	No	Yes	0	5	0	1
L:L:T6	R:R:L384	7.37	0	No	No	0	5	0	1
L:L:F7	R:R:L141	3.65	2	Yes	No	0	5	0	1
L:L:F7	R:R:L144	3.65	2	Yes	No	0	6	0	1
L:L:F7	R:R:Y148	11.35	2	Yes	Yes	0	7	0	1
L:L:F7	R:R:L388	4.87	2	Yes	Yes	0	7	0	1
L:L:T8	R:R:K197	9.01	0	No	Yes	0	6	0	1
L:L:S9	R:R:N300	7.45	0	No	No	0	6	0	1
L:L:D10	R:R:R380	9.53	0	No	No	0	5	0	1
L:L:S12	R:R:T298	6.4	1	No	No	0	5	0	1
L:L:S12	R:R:R299	10.54	1	No	Yes	0	4	0	1
L:L:Q14	R:R:L141	6.65	0	No	No	0	5	0	1
L:L:E16	R:R:S31	4.31	1	No	No	0	4	0	1
L:L:E16	R:R:Y205	13.47	1	No	No	0	3	0	1
L:L:E16	R:R:R299	11.63	1	No	Yes	0	4	0	1
L:L:A19	R:R:Q211	4.55	0	No	No	0	4	0	1
L:L:Q21	R:R:W91	26.29	0	No	No	0	4	0	1
L:L:F23	R:R:L32	4.87	3	Yes	No	0	4	0	1
L:L:F23	R:R:V36	3.93	3	Yes	No	0	2	0	1
L:L:F23	R:R:W39	6.01	3	Yes	Yes	0	5	0	1
L:L:F23	R:R:D215	9.55	3	Yes	No	0	3	0	1
L:L:I24	R:R:P90	5.08	0	No	Yes	0	4	0	1
L:L:W26	R:R:D215	4.47	3	No	No	0	3	0	1
L:L:L27	R:R:W39	12.53	3	No	Yes	0	5	0	1
L:L:L27	R:R:E68	6.63	3	No	No	0	4	0	1
L:L:K28	R:R:Y69	23.89	0	No	Yes	0	6	0	1
L:L:G30	R:R:E68	4.91	0	No	No	0	4	0	1
R:R:P90	R:R:V30	7.07	0	Yes	No	4	2	1	2
R:R:L32	R:R:T35	4.42	0	No	No	4	5	1	2
R:R:L32	R:R:W214	4.56	0	No	Yes	4	1	1	2
R:R:P90	R:R:T35	6.99	0	Yes	No	4	5	1	2
R:R:R40	R:R:V36	9.15	0	Yes	No	2	2	2	1
R:R:D215	R:R:V36	4.38	3	No	No	3	2	1	1
R:R:R40	R:R:W39	7	0	Yes	Yes	2	5	2	1
R:R:R43	R:R:W39	14.99	0	No	Yes	4	5	2	1
R:R:L123	R:R:Y69	10.55	0	No	Yes	5	6	2	1
R:R:S124	R:R:Y69	11.45	0	No	Yes	5	6	2	1
R:R:E127	R:R:W91	10.9	0	No	No	2	4	2	1
R:R:F381	R:R:L144	6.09	0	No	No	4	6	2	1
R:R:F385	R:R:L144	3.65	0	No	No	6	6	2	1
R:R:Y145	R:R:Y148	3.97	2	Yes	Yes	5	7	1	1
R:R:T149	R:R:Y145	11.24	2	No	Yes	7	5	1	1
R:R:D198	R:R:Y145	13.79	0	No	Yes	7	5	2	1
R:R:T149	R:R:Y148	3.75	2	No	Yes	7	7	1	1
R:R:Y148	R:R:Y152	3.97	2	Yes	Yes	7	7	1	1
R:R:V194	R:R:Y148	5.05	2	No	Yes	7	7	1	1
R:R:L388	R:R:Y148	4.69	2	Yes	Yes	7	7	1	1
R:R:G151	R:R:V150	3.68	2	No	No	8	5	2	1
R:R:G151	R:R:S392	3.71	2	No	No	8	9	2	2
R:R:R190	R:R:Y152	9.26	0	Yes	Yes	8	7	2	1
R:R:V194	R:R:Y152	10.09	2	No	Yes	7	7	1	1
R:R:S392	R:R:Y152	5.09	2	No	Yes	9	7	2	1
R:R:R190	R:R:V237	11.77	0	Yes	No	8	6	2	1
R:R:D198	R:R:K197	4.15	0	No	Yes	7	6	2	1
R:R:F230	R:R:K197	3.72	0	Yes	Yes	5	6	2	1
R:R:K197	R:R:M233	7.2	0	Yes	No	6	6	1	2
R:R:Q221	R:R:Y205	5.64	1	Yes	No	4	3	2	1
R:R:R299	R:R:Y205	5.14	1	Yes	No	4	3	1	1
R:R:Q210	R:R:Q211	3.84	1	Yes	No	4	4	2	1
R:R:Q210	R:R:W214	9.86	1	Yes	Yes	4	1	2	2
R:R:Q210	R:R:Q221	8.96	1	Yes	Yes	4	4	2	2
R:R:Q221	R:R:W214	15.33	1	Yes	Yes	4	1	2	2
R:R:F230	R:R:T298	7.78	0	Yes	No	5	5	2	1
R:R:M233	R:R:Q234	4.08	0	No	Yes	6	7	2	1
R:R:Q234	R:R:W284	13.14	5	Yes	Yes	7	8	1	2
R:R:I309	R:R:Q234	6.86	5	No	Yes	7	7	2	1
R:R:I309	R:R:W284	7.05	5	No	Yes	7	8	2	2
R:R:E294	R:R:R299	16.28	0	No	Yes	4	4	2	1
R:R:G295	R:R:R299	4.5	0	No	Yes	4	4	2	1
R:R:R299	R:R:T298	3.88	1	Yes	No	4	5	1	1
R:R:N300	R:R:W306	25.99	0	No	Yes	6	6	1	1
R:R:R310	R:R:W306	20.99	6	Yes	Yes	6	6	2	1
R:R:D372	R:R:W306	4.47	6	Yes	Yes	5	6	1	1
R:R:D372	R:R:R310	4.76	6	Yes	Yes	5	6	1	2
R:R:E364	R:R:E387	12.69	0	No	No	8	8	2	1
R:R:D372	R:R:R380	5.96	6	Yes	No	5	5	1	1
R:R:E387	R:R:K383	12.15	0	No	No	8	7	1	2
L:L:I24	R:R:W91	3.52	0	No	No	0	4	0	1
R:R:D67	R:R:Y69	3.45	0	No	Yes	9	6	2	1
R:R:K202	R:R:S206	3.06	0	No	No	4	4	1	2
R:R:D372	R:R:M303	2.77	6	Yes	No	5	5	1	2
R:R:F195	R:R:Y152	2.06	0	No	Yes	7	7	2	1
L:L:A20	R:R:P90	1.87	0	No	Yes	0	4	0	1
R:R:A375	R:R:R380	1.38	0	No	No	4	5	2	1
R:R:R299	R:R:T29	1.29	1	Yes	No	4	2	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8JIR_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.65
Number of Linked Nodes	393
Number of Links	423
Number of Hubs	55
Number of Links mediated by Hubs	213
Number of Communities	12
Number of Nodes involved in Communities	59
Number of Links involved in Communities	74

Path Summary
Number Of Nodes in MetaPath	79
Number Of Links MetaPath	78
Number of Shortest Paths	107345
Length Of Smallest Path	3
Average Path Length	20.4899
Length of Longest Path	59
Minimum Path Strength	1.345
Average Path Strength	7.35909
Maximum Path Strength	40.985
Minimum Path Correlation	0.7
Average Path Correlation	0.963413
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.5
Average % Of Corr. Nodes	58.1001
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.2655
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye
Gene Ontology	Biological Process	• positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • intracellular anatomical structure • cytoplasm • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • organelle • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • synapse • cell junction • cell body • glucagon receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • amide binding • binding • peptide hormone binding • hormone binding • glucagon-like peptide 1 receptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • heart process • multicellular organismal process • system process • regulation of biological process • regulation of heart contraction • regulation of system process • circulatory system process • regulation of blood circulation • regulation of multicellular organismal process • heart contraction • blood circulation • regulation of blood pressure • positive regulation of blood pressure • cellular response to stimulus • regulation of cellular process • response to stimulus • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to stress • response to psychosocial stress • cell surface receptor signaling pathway • behavior • learning or memory • nervous system process • cognition • transport • secretion • regulation of hormone levels • cell-cell signaling • export from cell • hormone secretion • establishment of localization • localization • secretion by cell • signal release • hormone transport • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • protein localization • establishment of protein localization • cellular localization • nitrogen compound transport • protein targeting • protein transmembrane transport • cellular macromolecule localization • establishment of localization in cell • post-translational protein targeting to membrane, translocation • establishment of protein localization to endoplasmic reticulum • protein localization to endoplasmic reticulum • establishment of protein localization to membrane • intracellular protein transmembrane transport • intracellular transport • post-translational protein targeting to endoplasmic reticulum membrane • localization within membrane • protein localization to membrane • protein targeting to membrane • transmembrane transport • establishment of protein localization to organelle • protein transport • macromolecule localization • protein localization to organelle • intracellular protein transport • protein targeting to ER • negative regulation of blood pressure • D2 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • D1 dopamine receptor binding • molecular function activator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of cellular localization • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • developmental process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of chemical stimulus • sensory perception • sensory perception of smell • cellular response to nitrogen compound • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • developmental growth • growth • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • homeostatic process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • regulation of protein secretion • regulation of secretion • regulation of hormone secretion • regulation of peptide secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • amide transport • regulation of signaling • regulation of transport • regulation of peptide transport • regulation of establishment of protein localization • regulation of protein transport • peptide transport • regulation of insulin secretion • peptide hormone secretion • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • lysosomal membrane • lysosome • Golgi apparatus • endomembrane system • ciliary basal body • Golgi apparatus subcompartment • organelle subcompartment • trans-Golgi network membrane • trans-Golgi network • G-protein beta-subunit binding
SCOP2	Domain Identifier	• FnI-like domain • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• FnI-like domain • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	D6M
PDB Residues	L:L:?2
Environment Details	Open EMBL-EBI Page
Code	D6M
Name	N-hexadecanoyl-L-glutamic acid
Synonyms
Identifier
Formula	C21 H39 N O5
Molecular Weight	385.538
SMILES
PubChem	161955
Formal Charge	0
Total Atoms	66
Total Chiral Atoms	1
Total Bonds	65
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>8JIR_nogp_Chain_R T V S L W E T V Q K W R E Y R R Q C Q R S L T E D P P P A T D L F C N R T F D E Y A C W P D G E P G S F V N V S C P W Y L P W A S S V P Q G H V Y R F C T A E G L W L Q K D N S S L P W R D L S E C E E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L S C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S V L S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F V R V I C I V V S K L K A N L M C K T D I K C R L A K S T L T L I P L L G T H E V I F A F V M D E H A R G T L R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	10.1038/s41421-024-00649-0
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	10.1073/pnas.2303696120
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	10.1073/pnas.2303696120
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	10.1016/j.apsb.2024.09.002
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	10.1021/jacs.4c12808
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	10.1073/pnas.2200155119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	10.1073/pnas.2200155119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	10.1073/pnas.2116506119
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	10.1073/pnas.2116506119
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	10.1038/s41467-022-28683-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	10.1038/s41467-021-27760-0
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	10.1038/s41589-021-00945-w
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	10.1038/s41467-021-24058-z
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	10.1038/s41467-021-24058-z
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	10.1016/j.str.2021.04.008
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	10.1073/pnas.2014879117
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	10.1038/s41422-020-0384-8
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	10.1038/s41589-020-0589-7
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	10.1038/s41586-019-1902-z
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	10.1038/nature25773
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	10.1038/nature22394
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378

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