psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D16	A:A:T11	4.34	No	No	0	4	4
2	A:A:D16	A:A:L12	5.43	No	No	0	4	2
3	A:A:D16	A:A:E15	6.5	No	No	0	4	5
4	A:A:V20	B:B:N88	7.39	No	Yes	0	3	7
5	A:A:E21	A:A:K24	5.4	No	No	0	3	4
6	A:A:E27	A:A:S23	5.75	No	No	0	6	7
7	A:A:S23	B:B:N88	5.96	No	Yes	0	7	7
8	A:A:I26	B:B:K89	4.36	Yes	Yes	0	9	9
9	A:A:I26	B:B:A92	3.25	Yes	No	0	9	6
10	A:A:E27	B:B:K89	8.1	No	Yes	0	6	9
11	A:A:K32	A:A:Q29	5.42	No	No	0	4	4
12	A:A:D33	A:A:Q29	7.83	No	No	0	5	4
13	A:A:Q31	R:R:Q263	5.12	No	No	0	4	5
14	A:A:D33	B:B:K78	6.91	No	No	0	5	8
15	A:A:K34	A:A:R38	6.19	No	No	0	4	4
16	A:A:K34	B:B:L55	5.64	No	No	0	4	6
17	A:A:K34	R:R:E262	8.1	No	No	0	4	6
18	A:A:Q35	R:R:S261	4.33	No	No	0	3	7
19	A:A:R38	A:A:Y37	5.14	No	Yes	0	4	4
20	A:A:R42	A:A:Y37	19.55	No	Yes	0	9	4
21	A:A:Y37	B:B:L55	7.03	Yes	No	22	4	6
22	A:A:Y37	B:B:D76	3.45	Yes	Yes	22	4	9
23	A:A:H220	A:A:T40	6.85	Yes	No	0	7	7
24	A:A:F219	A:A:H41	7.92	Yes	No	0	8	6
25	A:A:H41	A:A:T242	10.95	No	No	0	6	8
26	A:A:H41	A:A:I383	3.98	No	No	0	6	8
27	A:A:F222	A:A:R42	3.21	Yes	No	0	7	9
28	A:A:F219	A:A:L43	3.65	Yes	No	0	8	7
29	A:A:I245	A:A:L43	4.28	No	No	0	7	7
30	A:A:L44	A:A:L46	5.54	No	No	0	9	8
31	A:A:F238	A:A:L44	17.05	Yes	No	0	9	9
32	A:A:I244	A:A:L44	5.71	No	No	0	8	9
33	A:A:L45	A:A:M221	8.48	No	Yes	0	8	8
34	A:A:G47	A:A:S51	3.71	No	Yes	6	9	9
35	A:A:G47	A:A:K53	3.49	No	Yes	6	9	9
36	A:A:D49	A:A:R265	7.15	No	Yes	0	8	9
37	A:A:D249	A:A:N50	9.42	Yes	Yes	18	8	9
38	A:A:D252	A:A:N50	5.39	No	Yes	18	8	9
39	A:A:N50	A:A:R265	15.67	Yes	Yes	18	9	9
40	A:A:G52	A:A:S51	3.71	No	Yes	0	9	9
41	A:A:K53	A:A:S51	4.59	Yes	Yes	6	9	9
42	A:A:S51	A:A:V247	4.85	Yes	No	6	9	7
43	A:A:D223	A:A:K53	9.68	No	Yes	0	9	9
44	A:A:K53	A:A:V247	4.55	Yes	No	6	9	7
45	A:A:I56	A:A:N292	4.25	No	No	0	7	9
46	A:A:T210	A:A:V57	4.76	No	No	0	7	7
47	A:A:F212	A:A:M60	7.46	No	No	11	9	9
48	A:A:M221	A:A:M60	4.33	Yes	No	11	8	9
49	A:A:H64	A:A:R61	4.51	No	No	0	8	8
50	A:A:V214	A:A:Y63	3.79	No	No	0	6	9
51	A:A:A372	A:A:Y63	9.34	No	No	0	8	9
52	A:A:Q194	A:A:Q195	7.68	No	No	0	5	8
53	A:A:L198	A:A:Q195	3.99	No	No	0	9	8
54	A:A:L198	A:A:T200	4.42	No	No	0	9	7
55	A:A:R199	A:A:T200	3.88	No	No	0	7	7
56	A:A:R201	A:A:S205	11.86	No	No	23	9	7
57	A:A:F208	A:A:R201	10.69	Yes	No	23	5	9
58	A:A:A226	A:A:T204	3.36	No	No	0	9	9
59	A:A:F208	A:A:S205	6.61	Yes	No	23	5	7
60	A:A:G206	B:B:N119	5.09	No	No	0	8	9
61	A:A:I207	B:B:W99	3.52	No	Yes	0	9	9
62	A:A:D223	A:A:F208	3.58	No	Yes	0	9	5
63	A:A:F208	A:A:G225	4.52	Yes	No	0	5	9
64	A:A:E209	A:A:K211	4.05	No	No	17	9	4
65	A:A:E209	A:A:H220	9.85	No	Yes	17	9	7
66	A:A:E209	A:A:F222	9.33	No	Yes	17	9	7
67	A:A:M221	A:A:T210	4.52	Yes	No	0	8	7
68	A:A:H220	A:A:K211	18.34	Yes	No	17	7	4
69	A:A:F212	A:A:F219	11.79	No	Yes	11	9	8
70	A:A:F212	A:A:M221	3.73	No	Yes	11	9	8
71	A:A:K216	A:A:Q213	4.07	No	No	0	4	3
72	A:A:N218	A:A:Q213	15.85	No	No	0	4	3
73	A:A:R373	A:A:V214	3.92	No	No	0	5	6
74	A:A:F376	A:A:V214	6.55	Yes	No	0	8	6
75	A:A:D215	A:A:R373	10.72	No	No	0	5	5
76	A:A:D215	A:A:F376	3.58	No	Yes	0	5	8
77	A:A:F219	A:A:V217	10.49	Yes	No	11	8	5
78	A:A:F376	A:A:V217	3.93	Yes	No	11	8	5
79	A:A:F219	A:A:F376	5.36	Yes	Yes	11	8	8
80	A:A:C379	A:A:F219	5.59	No	Yes	0	8	8
81	A:A:F222	A:A:H220	4.53	Yes	Yes	17	7	7
82	A:A:F222	B:B:W99	23.05	Yes	Yes	0	7	9
83	A:A:Q227	A:A:V224	5.73	Yes	No	1	9	9
84	A:A:V224	A:A:W234	14.71	No	Yes	1	9	9
85	A:A:Q227	A:A:W234	4.38	Yes	Yes	1	9	9
86	A:A:Q227	B:B:L117	3.99	Yes	No	0	9	9
87	A:A:Q227	B:B:N119	5.28	Yes	No	0	9	9
88	A:A:Q227	B:B:Y145	7.89	Yes	Yes	1	9	8
89	A:A:E230	A:A:R228	13.96	No	No	0	9	9
90	A:A:R228	B:B:T164	6.47	No	No	0	9	6
91	A:A:R228	B:B:D186	9.53	No	No	0	9	9
92	A:A:E230	A:A:R232	10.47	No	No	0	9	8
93	A:A:R231	A:A:W234	8	No	Yes	1	9	9
94	A:A:I235	A:A:R231	3.76	No	No	1	9	9
95	A:A:I276	A:A:R231	5.01	No	No	0	8	9
96	A:A:R232	B:B:D228	13.1	No	Yes	0	8	9
97	A:A:K233	A:A:Q236	4.07	Yes	No	1	9	8
98	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
99	A:A:K233	B:B:M188	10.08	Yes	No	1	9	8
100	A:A:K233	B:B:C204	4.85	Yes	No	1	9	7
101	A:A:K233	B:B:D228	6.91	Yes	Yes	1	9	9
102	A:A:I235	A:A:W234	4.7	No	Yes	1	9	9
103	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
104	A:A:W234	B:B:Y145	5.79	Yes	Yes	1	9	8
105	A:A:Q236	A:A:W281	7.67	No	Yes	1	8	5
106	A:A:Q236	B:B:R314	9.35	No	Yes	1	8	8
107	A:A:C237	A:A:F238	8.38	No	Yes	0	8	9
108	A:A:C237	B:B:Y59	4.03	No	Yes	1	8	8
109	A:A:C237	B:B:Q75	7.63	No	Yes	1	8	9
110	A:A:F238	B:B:W99	9.02	Yes	Yes	0	9	9
111	A:A:D240	A:A:N239	8.08	No	No	1	6	8
112	A:A:N239	B:B:K57	9.79	No	Yes	1	8	9
113	A:A:N239	B:B:W332	10.17	No	Yes	1	8	9
114	A:A:D240	B:B:K57	6.91	No	Yes	1	6	9
115	A:A:C379	A:A:T242	5.07	No	No	0	8	8
116	A:A:A243	A:A:I288	3.25	No	No	0	8	9
117	A:A:I244	A:A:I285	4.42	No	No	0	8	7
118	A:A:I245	A:A:I375	4.42	No	No	0	7	9
119	A:A:D272	A:A:F246	8.36	No	No	0	8	9
120	A:A:F246	A:A:F273	5.36	No	Yes	0	9	9
121	A:A:F246	A:A:L289	3.65	No	Yes	0	9	9
122	A:A:F290	A:A:V247	5.24	Yes	No	6	9	7
123	A:A:A269	A:A:V248	3.39	No	No	0	9	7
124	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
125	A:A:D249	A:A:S251	5.89	Yes	No	0	8	9
126	A:A:D249	A:A:D252	5.32	Yes	No	18	8	8
127	A:A:D249	A:A:K293	16.59	Yes	No	0	8	9
128	A:A:Q294	A:A:S250	5.78	Yes	No	14	6	6
129	A:A:L297	A:A:S250	6.01	No	No	14	8	6
130	A:A:L296	A:A:S251	6.01	No	No	0	6	9
131	A:A:D252	A:A:R265	3.57	No	Yes	18	8	9
132	A:A:L297	A:A:Y253	3.52	No	Yes	0	8	8
133	A:A:K300	A:A:Y253	9.55	No	Yes	0	9	8
134	A:A:I308	A:A:Y253	3.63	No	Yes	0	7	8
135	A:A:Y253	A:A:Y311	8.94	Yes	No	0	8	6
136	A:A:N264	A:A:Y311	8.14	No	No	0	9	6
137	A:A:E268	A:A:R265	9.3	No	Yes	0	9	9
138	A:A:F312	A:A:L266	7.31	Yes	No	0	8	8
139	A:A:I341	A:A:L266	5.71	No	No	0	8	8
140	A:A:L270	A:A:Q267	3.99	Yes	No	0	6	4
141	A:A:N271	A:A:Q267	7.92	No	No	0	5	4
142	A:A:F312	A:A:Q267	3.51	Yes	No	0	8	4
143	A:A:E344	A:A:L270	3.98	No	Yes	0	5	6
144	A:A:F345	A:A:L270	9.74	Yes	Yes	0	8	6
145	A:A:I348	A:A:L270	4.28	No	Yes	0	4	6
146	A:A:F273	A:A:V287	5.24	Yes	No	0	9	6
147	A:A:F273	A:A:F345	9.65	Yes	Yes	0	9	8
148	A:A:F273	A:A:I348	6.28	Yes	No	0	9	4
149	A:A:K274	A:A:N278	4.2	No	No	0	5	8
150	A:A:I348	A:A:K274	5.82	No	No	0	4	5
151	A:A:N278	A:A:W277	5.65	No	Yes	0	8	6
152	A:A:V287	A:A:W277	3.68	No	Yes	0	6	6
153	A:A:S349	A:A:W277	3.71	No	Yes	0	7	6
154	A:A:H357	A:A:W277	26.45	No	Yes	0	7	6
155	A:A:N278	A:A:S352	5.96	No	No	0	8	5
156	A:A:N279	A:A:W281	3.39	No	Yes	0	8	5
157	A:A:L282	A:A:N279	10.98	No	No	0	9	8
158	A:A:R280	A:A:W281	17.99	No	Yes	0	5	5
159	A:A:R280	A:A:R283	4.26	No	No	0	5	3
160	A:A:W281	B:B:D290	6.7	Yes	Yes	1	5	6
161	A:A:W281	B:B:R314	22.99	Yes	Yes	1	5	8
162	A:A:W281	B:B:W332	5.62	Yes	Yes	1	5	9
163	A:A:R283	A:A:R356	8.53	No	No	0	3	2
164	A:A:S286	A:A:Y360	3.82	No	Yes	12	8	8
165	A:A:I382	A:A:S286	9.29	No	No	12	6	8
166	A:A:F290	A:A:I288	3.77	Yes	No	0	9	9
167	A:A:D378	A:A:I288	12.59	No	No	0	7	9
168	A:A:L289	A:A:L291	5.54	Yes	No	0	9	8
169	A:A:F345	A:A:L289	7.31	Yes	Yes	0	8	9
170	A:A:L289	A:A:P361	3.28	Yes	No	0	9	5
171	A:A:F290	A:A:H362	7.92	Yes	No	6	9	9
172	A:A:F290	A:A:T364	5.19	Yes	Yes	6	9	9
173	A:A:F290	A:A:R374	3.21	Yes	Yes	6	9	4
174	A:A:F290	A:A:I375	5.02	Yes	No	0	9	9
175	A:A:F363	A:A:L291	4.87	Yes	No	0	5	8
176	A:A:K293	A:A:N292	6.99	No	No	0	9	9
177	A:A:N292	A:A:T364	4.39	No	Yes	0	9	9
178	A:A:K293	A:A:L296	4.23	No	No	0	9	6
179	A:A:L297	A:A:Q294	5.32	No	Yes	14	8	6
180	A:A:K338	A:A:Q294	8.14	No	Yes	14	5	6
181	A:A:F363	A:A:Q294	15.23	Yes	Yes	14	5	6
182	A:A:D295	A:A:L296	6.79	No	No	0	9	6
183	A:A:C365	A:A:D295	9.34	No	No	25	8	9
184	A:A:D295	A:A:S366	8.83	No	No	25	9	9
185	A:A:A298	A:A:V334	3.39	No	Yes	0	4	4
186	A:A:V301	A:A:V334	3.21	No	Yes	26	7	4
187	A:A:D331	A:A:L302	4.07	No	No	0	4	2
188	A:A:E309	A:A:I308	4.1	No	No	24	4	7
189	A:A:F315	A:A:I308	3.77	Yes	No	24	6	7
190	A:A:E309	A:A:F315	7	No	Yes	24	4	6
191	A:A:D310	A:A:Y311	10.34	No	No	0	3	6
192	A:A:E314	A:A:F312	4.66	No	Yes	0	6	8
193	A:A:F312	A:A:F340	6.43	Yes	Yes	0	8	7
194	A:A:F315	A:A:R336	22.45	Yes	No	0	6	5
195	A:A:F315	A:A:F340	10.72	Yes	Yes	0	6	7
196	A:A:P321	A:A:Y318	5.56	Yes	Yes	0	5	6
197	A:A:R336	A:A:Y318	5.14	No	Yes	0	5	6
198	A:A:F340	A:A:Y318	7.22	Yes	Yes	0	7	6
199	A:A:D343	A:A:Y318	9.2	No	Yes	0	3	6
200	A:A:P321	A:A:T320	3.5	Yes	No	0	5	1
201	A:A:R336	A:A:T320	3.88	No	No	0	5	1
202	A:A:D323	A:A:P321	4.83	No	Yes	0	4	5
203	A:A:P321	A:A:Y339	9.74	Yes	Yes	0	5	3
204	A:A:A324	A:A:P326	3.74	No	No	0	3	1
205	A:A:A324	A:A:Y339	4	No	Yes	0	3	3
206	A:A:P326	A:A:T335	6.99	No	No	0	1	4
207	A:A:E327	A:A:P328	7.86	No	No	0	4	1
208	A:A:E330	A:A:V334	7.13	Yes	Yes	0	3	4
209	A:A:E330	A:A:T335	9.88	Yes	No	0	3	4
210	A:A:E330	A:A:K338	12.15	Yes	No	0	3	5
211	A:A:D331	A:A:P332	9.66	No	No	0	4	1
212	A:A:D331	A:A:R333	21.44	No	No	0	4	5
213	A:A:F363	A:A:K338	6.2	Yes	No	14	5	5
214	A:A:R342	A:A:Y339	8.23	Yes	Yes	0	4	3
215	A:A:E344	A:A:F340	9.33	No	Yes	0	5	7
216	A:A:D343	A:A:R342	5.96	No	Yes	0	3	4
217	A:A:L346	A:A:R342	7.29	No	Yes	0	4	4
218	A:A:P361	A:A:R342	7.21	No	Yes	0	5	4
219	A:A:F363	A:A:R342	6.41	Yes	Yes	0	5	4
220	A:A:E344	A:A:R347	13.96	No	No	0	5	4
221	A:A:L346	A:A:S349	4.5	No	No	0	4	7
222	A:A:C359	A:A:S349	3.44	No	No	0	5	7
223	A:A:G353	A:A:S352	3.71	No	No	0	4	5
224	A:A:G353	A:A:H357	4.77	No	No	0	4	7
225	A:A:D354	A:A:G355	5.03	No	No	0	3	2
226	A:A:D354	A:A:R356	13.1	No	No	0	3	2
227	A:A:H357	A:A:R356	6.77	No	No	0	7	2
228	A:A:R385	A:A:Y358	6.17	Yes	No	0	5	4
229	A:A:Y358	R:R:L339	4.69	No	No	0	4	7
230	A:A:D378	A:A:Y360	11.49	No	Yes	0	7	8
231	A:A:D381	A:A:Y360	10.34	No	Yes	12	8	8
232	A:A:I382	A:A:Y360	8.46	No	Yes	12	6	8
233	A:A:H362	A:A:R374	14.67	No	Yes	6	9	4
234	A:A:D378	A:A:H362	10.08	No	No	0	7	9
235	A:A:D368	A:A:T364	5.78	No	Yes	6	9	9
236	A:A:N371	A:A:T364	13.16	No	Yes	6	9	9
237	A:A:R374	A:A:T364	3.88	Yes	Yes	6	4	9
238	A:A:C365	A:A:S366	5.16	No	No	25	8	9
239	A:A:S366	A:A:V367	4.85	No	No	0	9	9
240	A:A:D368	A:A:E370	9.09	No	No	6	9	4
241	A:A:D368	A:A:R374	7.15	No	Yes	6	9	4
242	A:A:E370	A:A:R374	13.96	No	Yes	6	4	4
243	A:A:N371	A:A:R374	6.03	No	Yes	6	9	4
244	A:A:F376	A:A:N377	4.83	Yes	No	0	8	4
245	A:A:D381	A:A:R385	13.1	No	Yes	12	8	5
246	A:A:D381	R:R:K334	6.91	No	Yes	12	8	9
247	A:A:Q384	R:R:K334	9.49	No	Yes	0	6	9
248	A:A:R385	R:R:K334	7.43	Yes	Yes	12	5	9
249	A:A:H387	A:A:M386	6.57	No	No	0	8	3
250	A:A:M386	A:A:R389	4.96	No	No	0	3	4
251	A:A:H387	R:R:L254	14.14	No	No	0	8	8
252	A:A:L388	A:A:L394	4.15	No	No	0	8	8
253	A:A:L388	R:R:L255	6.92	No	Yes	0	8	8
254	A:A:Q390	R:R:R176	4.67	No	Yes	0	4	9
255	A:A:Y391	R:R:R176	10.29	Yes	Yes	0	4	9
256	A:A:Y391	R:R:E247	3.37	Yes	Yes	0	4	9
257	A:A:Y391	R:R:Y250	4.96	Yes	Yes	0	4	8
258	A:A:Y391	R:R:L251	8.21	Yes	No	0	4	9
259	A:A:E392	R:R:N406	3.94	No	No	0	6	9
260	A:A:E392	R:R:N407	3.94	No	No	0	6	6
261	A:A:L393	R:R:L356	8.3	No	No	0	8	9
262	A:A:L394	R:R:K334	4.23	No	Yes	0	8	9
263	B:B:L4	B:B:R8	8.5	No	No	0	4	3
264	B:B:D5	B:B:Q9	3.92	No	No	0	1	3
265	B:B:L7	G:G:A12	4.73	No	No	0	8	5
266	B:B:L7	G:G:R13	10.93	No	No	0	8	6
267	B:B:E10	G:G:V16	8.56	No	No	0	8	7
268	B:B:E10	G:G:K20	4.05	No	No	0	8	6
269	B:B:E12	B:B:K15	8.1	No	No	0	4	6
270	B:B:L14	G:G:L19	5.54	No	No	0	8	9
271	B:B:L14	G:G:K20	5.64	No	No	0	8	6
272	B:B:N16	B:B:R19	12.05	No	No	0	1	4
273	B:B:I18	B:B:R22	5.01	No	No	0	7	6
274	B:B:I18	G:G:A23	3.25	No	Yes	0	7	8
275	B:B:A21	G:G:R27	4.15	No	Yes	0	4	8
276	B:B:D258	B:B:R22	10.72	Yes	No	0	7	6
277	B:B:Q259	B:B:R22	3.5	Yes	No	0	6	6
278	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
279	B:B:D27	G:G:K29	6.91	No	No	0	8	4
280	B:B:D27	G:G:S31	8.83	No	No	0	8	9
281	B:B:Q32	B:B:T29	12.76	No	No	0	1	3
282	B:B:L30	B:B:T34	4.42	No	Yes	0	5	5
283	B:B:L30	B:B:M262	7.07	No	Yes	0	5	4
284	B:B:I33	G:G:A34	4.87	No	No	0	3	6
285	B:B:I37	B:B:T34	4.56	No	Yes	0	2	5
286	B:B:T34	G:G:M38	7.53	Yes	No	0	5	4
287	B:B:N35	B:B:N36	5.45	No	No	0	1	1
288	B:B:I37	B:B:K301	4.36	No	No	0	2	5
289	B:B:I37	G:G:E42	4.1	No	No	0	2	1
290	B:B:R283	B:B:V40	6.54	Yes	Yes	29	9	3
291	B:B:D298	B:B:V40	8.76	No	Yes	29	9	3
292	B:B:G306	B:B:R42	4.5	No	No	0	4	2
293	B:B:I43	B:B:L284	5.71	No	No	0	3	5
294	B:B:Q44	B:B:R46	8.18	No	No	0	4	5
295	B:B:L308	B:B:M45	4.24	No	No	9	7	4
296	B:B:M45	B:B:W339	3.49	No	Yes	9	4	9
297	B:B:M45	G:G:L50	5.65	No	No	0	4	9
298	B:B:R46	B:B:R48	5.33	No	No	0	5	7
299	B:B:K337	B:B:T47	9.01	Yes	No	9	6	3
300	B:B:T47	B:B:W339	9.7	No	Yes	9	3	9
301	B:B:N340	B:B:R48	6.03	No	No	0	9	7
302	B:B:R49	B:B:T87	5.17	No	No	0	7	5
303	B:B:I338	B:B:R49	5.01	Yes	No	8	5	7
304	B:B:R49	G:G:F61	6.41	No	Yes	8	7	8
305	B:B:R52	B:B:T50	9.06	No	No	0	7	3
306	B:B:K337	B:B:T50	6.01	Yes	No	0	6	3
307	B:B:L51	B:B:W82	13.67	No	Yes	8	9	9
308	B:B:L336	B:B:L51	4.15	Yes	No	8	7	9
309	B:B:I338	B:B:L51	4.28	Yes	No	8	5	9
310	B:B:F335	B:B:R52	9.62	No	No	0	4	7
311	B:B:R52	R:R:R170	14.93	No	No	0	7	8
312	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
313	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
314	B:B:H54	B:B:S72	9.76	Yes	No	0	9	9
315	B:B:H54	B:B:S74	12.55	Yes	No	0	9	9
316	B:B:H54	B:B:I80	11.93	Yes	No	0	9	8
317	B:B:D76	B:B:L55	12.21	Yes	No	22	9	6
318	B:B:K57	B:B:Y59	4.78	Yes	Yes	1	9	8
319	B:B:K57	B:B:Q75	14.92	Yes	Yes	1	9	9
320	B:B:K57	B:B:W332	18.57	Yes	Yes	1	9	9
321	B:B:Q75	B:B:Y59	12.4	Yes	Yes	1	9	8
322	B:B:M101	B:B:Y59	8.38	No	Yes	0	9	8
323	B:B:W332	B:B:Y59	5.79	Yes	Yes	1	9	8
324	B:B:C317	B:B:M61	4.86	No	No	0	7	6
325	B:B:A328	B:B:M61	3.22	No	No	0	5	6
326	B:B:L336	B:B:M61	4.24	Yes	No	0	7	6
327	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
328	B:B:H62	B:B:R150	16.93	No	No	0	6	6
329	B:B:L70	B:B:W63	6.83	No	Yes	0	5	7
330	B:B:S84	B:B:W63	6.18	No	Yes	0	5	7
331	B:B:T321	B:B:W63	9.7	No	Yes	0	7	7
332	B:B:A328	B:B:W63	5.19	No	Yes	0	5	7
333	B:B:I338	B:B:W63	4.7	Yes	Yes	0	5	7
334	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
335	B:B:D66	B:B:R68	3.57	No	No	0	8	5
336	B:B:D66	B:B:L69	9.5	No	No	0	8	5
337	B:B:S67	B:B:T321	4.8	No	No	30	5	7
338	B:B:D322	B:B:S67	4.42	No	No	0	1	5
339	B:B:D323	B:B:S67	10.31	No	No	30	7	5
340	B:B:D83	B:B:R68	17.87	No	No	0	8	5
341	B:B:R68	B:B:Y85	28.81	No	No	0	5	4
342	B:B:L69	B:B:Y105	3.52	No	Yes	0	5	6
343	B:B:I81	B:B:V71	4.61	Yes	No	5	7	8
344	B:B:V71	B:B:Y105	7.57	No	Yes	5	8	6
345	B:B:V112	B:B:V71	3.21	Yes	No	5	8	8
346	B:B:S72	B:B:W82	7.41	No	Yes	8	9	9
347	B:B:L336	B:B:S72	6.01	Yes	No	8	7	9
348	B:B:A73	B:B:V100	3.39	No	No	0	9	9
349	B:B:A73	B:B:C103	3.61	No	No	0	9	8
350	B:B:D76	B:B:S74	7.36	Yes	No	0	9	9
351	B:B:Q75	B:B:W99	6.57	Yes	Yes	0	9	9
352	B:B:D76	B:B:K78	8.3	Yes	No	0	9	8
353	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
354	B:B:K78	B:B:P94	3.35	No	No	0	8	5
355	B:B:L79	B:B:L95	4.15	No	Yes	0	7	8
356	B:B:C114	B:B:L79	6.35	Yes	No	0	8	7
357	B:B:I80	B:B:W82	16.44	No	Yes	0	8	9
358	B:B:H91	B:B:I81	9.28	Yes	Yes	5	5	7
359	B:B:I81	B:B:Y105	3.63	Yes	Yes	5	7	6
360	B:B:I81	B:B:L126	4.28	Yes	Yes	5	7	5
361	B:B:K89	B:B:W82	8.12	Yes	Yes	0	9	9
362	B:B:L336	B:B:W82	3.42	Yes	Yes	8	7	9
363	B:B:D83	B:B:T86	5.78	No	No	0	8	6
364	B:B:S84	G:G:F61	5.28	No	Yes	0	5	8
365	B:B:Y85	G:G:P60	15.3	No	Yes	8	4	9
366	B:B:Y85	G:G:F61	7.22	No	Yes	8	4	8
367	B:B:N88	B:B:T86	8.77	Yes	No	0	7	6
368	B:B:H91	B:B:V90	6.92	Yes	No	0	5	5
369	B:B:H91	B:B:L126	5.14	Yes	Yes	5	5	5
370	B:B:H91	B:B:V133	4.15	Yes	No	0	5	4
371	B:B:I93	B:B:P94	3.39	No	No	0	7	5
372	B:B:I93	B:B:V133	7.68	No	No	0	7	4
373	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
374	B:B:L95	B:B:Y124	5.86	Yes	Yes	0	8	6
375	B:B:R96	B:B:V135	5.23	No	Yes	5	6	4
376	B:B:E138	B:B:R96	9.3	No	No	5	6	6
377	B:B:D118	B:B:S97	10.31	No	No	0	9	8
378	B:B:S98	B:B:W99	7.41	No	Yes	0	8	9
379	B:B:L117	B:B:W99	4.56	No	Yes	0	9	9
380	B:B:G116	B:B:M101	5.24	No	No	0	9	9
381	B:B:M101	B:B:Y145	8.38	No	Yes	0	9	8
382	B:B:C148	B:B:T102	3.38	No	No	0	6	8
383	B:B:C149	B:B:T102	5.07	No	No	0	8	8
384	B:B:V112	B:B:Y105	5.05	Yes	Yes	5	8	6
385	B:B:L126	B:B:Y105	3.52	Yes	Yes	5	5	6
386	B:B:A106	B:B:F151	5.55	No	Yes	0	6	9
387	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
388	B:B:N110	B:B:S108	7.45	Yes	No	3	4	6
389	B:B:D154	B:B:S108	8.83	No	No	3	6	6
390	B:B:N110	B:B:Y111	3.49	Yes	Yes	3	4	4
391	B:B:K127	B:B:N110	5.6	No	Yes	0	4	4
392	B:B:D154	B:B:N110	6.73	No	Yes	3	6	4
393	B:B:I123	B:B:Y111	3.63	Yes	Yes	3	6	4
394	B:B:N125	B:B:Y111	15.12	No	Yes	0	4	4
395	B:B:D154	B:B:Y111	9.2	No	Yes	3	6	4
396	B:B:V112	B:B:Y124	3.79	Yes	Yes	5	8	6
397	B:B:L126	B:B:V112	4.47	Yes	Yes	5	5	8
398	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
399	B:B:C114	B:B:G115	3.92	Yes	No	0	8	9
400	B:B:C114	B:B:S122	3.44	Yes	No	5	8	8
401	B:B:C114	B:B:Y124	5.38	Yes	Yes	5	8	6
402	B:B:G115	B:B:L146	3.42	No	No	0	9	7
403	B:B:D118	B:B:I120	4.2	No	No	0	9	6
404	B:B:G144	B:B:N119	5.09	No	No	0	8	9
405	B:B:A140	B:B:I120	3.25	No	No	0	5	6
406	B:B:C121	B:B:L139	4.76	No	No	0	8	9
407	B:B:C121	B:B:T159	3.38	No	Yes	0	8	9
408	B:B:S122	B:B:Y124	6.36	No	Yes	5	8	6
409	B:B:I123	B:B:L139	4.28	Yes	No	0	6	9
410	B:B:F151	B:B:I123	5.02	Yes	Yes	3	9	6
411	B:B:I123	B:B:I171	8.83	Yes	Yes	3	6	6
412	B:B:V135	B:B:Y124	5.05	Yes	Yes	5	4	6
413	B:B:E138	B:B:V135	4.28	No	Yes	5	6	4
414	B:B:L139	B:B:W169	11.39	No	Yes	0	9	8
415	B:B:H142	B:B:L146	3.86	Yes	No	3	9	7
416	B:B:H142	B:B:T159	6.85	Yes	Yes	3	9	9
417	B:B:H142	B:B:S161	16.74	Yes	No	3	9	9
418	B:B:D163	B:B:H142	7.56	Yes	Yes	3	9	9
419	B:B:H142	B:B:W169	7.41	Yes	Yes	3	9	8
420	B:B:H142	B:B:Q176	3.71	Yes	Yes	3	9	4
421	B:B:D163	B:B:T143	8.67	Yes	No	0	9	5
422	B:B:G162	B:B:Y145	7.24	No	Yes	1	9	8
423	B:B:D186	B:B:Y145	10.34	No	Yes	1	9	8
424	B:B:L146	B:B:T159	8.84	No	Yes	3	7	9
425	B:B:S147	B:B:S160	4.89	No	No	0	9	6
426	B:B:C148	B:B:R150	4.18	No	No	0	6	6
427	B:B:C148	B:B:L190	4.76	No	No	0	6	5
428	B:B:C149	B:B:I157	3.27	No	Yes	0	8	7
429	B:B:F151	B:B:I157	7.54	Yes	Yes	3	9	7
430	B:B:F151	B:B:I171	3.77	Yes	Yes	3	9	6
431	B:B:L152	B:B:Q156	3.99	No	Yes	0	3	5
432	B:B:L152	B:B:L192	6.92	No	No	0	3	5
433	B:B:D153	B:B:Q156	13.05	No	Yes	0	5	5
434	B:B:D170	B:B:N155	8.08	No	No	0	9	3
435	B:B:E172	B:B:N155	6.57	No	No	0	6	3
436	B:B:L168	B:B:Q156	3.99	No	Yes	0	6	5
437	B:B:Q156	B:B:R214	4.67	Yes	No	0	5	9
438	B:B:I157	B:B:W169	3.52	Yes	Yes	3	7	8
439	B:B:I157	B:B:I171	4.42	Yes	Yes	3	7	6
440	B:B:L190	B:B:V158	4.47	No	No	0	5	5
441	B:B:F199	B:B:V158	3.93	Yes	No	0	9	5
442	B:B:T159	B:B:W169	9.7	Yes	Yes	3	9	8
443	B:B:C166	B:B:S160	3.44	No	No	7	8	6
444	B:B:S160	B:B:V187	6.46	No	Yes	7	6	9
445	B:B:D163	B:B:S161	8.83	Yes	No	3	9	9
446	B:B:D186	B:B:G162	6.71	No	No	1	9	9
447	B:B:D163	B:B:T165	10.12	Yes	No	0	9	7
448	B:B:G185	B:B:T164	3.64	No	No	0	5	6
449	B:B:T165	B:B:T181	4.71	No	No	0	7	2
450	B:B:C166	B:B:V187	5.12	No	Yes	7	8	9
451	B:B:C166	B:B:S201	3.44	No	Yes	7	8	9
452	B:B:A167	B:B:W169	5.19	No	Yes	3	4	8
453	B:B:A167	B:B:Q176	6.06	No	Yes	3	4	4
454	B:B:L168	B:B:T178	4.42	No	No	0	6	4
455	B:B:L168	B:B:V213	4.47	No	No	0	6	4
456	B:B:Q176	B:B:W169	16.43	Yes	Yes	3	4	8
457	B:B:D170	B:B:T173	10.12	No	Yes	0	9	5
458	B:B:D170	B:B:T177	4.34	No	No	0	9	4
459	B:B:E172	B:B:T173	5.64	No	Yes	0	6	5
460	B:B:Q175	B:B:T173	4.25	No	Yes	0	4	5
461	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
462	B:B:F180	B:B:T178	3.89	Yes	No	0	7	4
463	B:B:F180	B:B:F199	11.79	Yes	Yes	7	7	9
464	B:B:F180	B:B:W211	13.03	Yes	Yes	7	7	8
465	B:B:G182	B:B:K209	3.49	No	Yes	0	6	6
466	B:B:H183	B:B:V187	5.54	Yes	Yes	7	9	9
467	B:B:H183	B:B:S201	6.97	Yes	Yes	7	9	9
468	B:B:A203	B:B:H183	8.78	No	Yes	7	8	9
469	B:B:D205	B:B:H183	8.82	No	Yes	0	9	9
470	B:B:H183	B:B:K209	15.72	Yes	Yes	7	9	6
471	B:B:D205	B:B:T184	7.23	No	No	0	9	3
472	B:B:S201	B:B:V187	3.23	Yes	Yes	7	9	9
473	B:B:A203	B:B:V187	5.09	No	Yes	7	8	9
474	B:B:C204	B:B:M188	3.24	No	No	1	7	8
475	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
476	B:B:F234	B:B:S191	5.28	No	No	0	5	8
477	B:B:F199	B:B:L192	3.65	Yes	No	0	9	5
478	B:B:A193	B:B:F234	4.16	No	No	0	4	5
479	B:B:G238	B:B:P194	4.06	No	No	0	7	4
480	B:B:D195	B:B:R197	3.57	No	No	0	5	5
481	B:B:L198	B:B:L210	6.92	No	No	0	3	5
482	B:B:D212	B:B:L198	5.43	No	No	0	9	3
483	B:B:F199	B:B:W211	13.03	Yes	Yes	7	9	8
484	B:B:I232	B:B:V200	7.68	Yes	Yes	2	8	6
485	B:B:F234	B:B:V200	14.42	No	Yes	0	5	6
486	B:B:F241	B:B:V200	6.55	Yes	Yes	2	6	6
487	B:B:S201	B:B:W211	7.41	Yes	Yes	7	9	8
488	B:B:G202	B:B:I229	3.53	No	No	0	6	7
489	B:B:C204	B:B:D228	10.89	No	Yes	1	7	9
490	B:B:D205	B:B:S207	8.83	No	No	0	9	5
491	B:B:K209	B:B:W211	8.12	Yes	Yes	7	6	8
492	B:B:C218	B:B:K209	9.7	No	Yes	7	5	6
493	B:B:K209	B:B:T221	12.01	Yes	No	0	6	7
494	B:B:L210	B:B:L255	4.15	No	No	0	5	6
495	B:B:C218	B:B:W211	5.22	No	Yes	7	5	8
496	B:B:D212	B:B:E215	7.8	No	No	0	9	3
497	B:B:D212	B:B:R219	10.72	No	No	0	9	5
498	B:B:R214	B:B:V213	5.23	No	No	0	9	4
499	B:B:E215	B:B:M217	5.41	No	No	0	3	3
500	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
501	B:B:F222	B:B:Q220	9.37	Yes	No	2	8	7
502	B:B:D258	B:B:Q220	13.05	Yes	No	2	7	7
503	B:B:T221	G:G:E22	9.88	No	No	0	7	9
504	B:B:F222	B:B:F241	12.86	Yes	Yes	2	8	6
505	B:B:F222	B:B:F253	6.43	Yes	Yes	2	8	6
506	B:B:D258	B:B:F222	4.78	Yes	Yes	2	7	8
507	B:B:H225	B:B:I229	9.28	Yes	No	2	9	7
508	B:B:H225	B:B:T243	8.21	Yes	Yes	2	9	8
509	B:B:H225	B:B:S245	13.95	Yes	No	2	9	9
510	B:B:D247	B:B:H225	8.82	Yes	Yes	2	9	9
511	B:B:H225	B:B:R251	14.67	Yes	Yes	2	9	8
512	B:B:D247	B:B:E226	3.9	Yes	No	0	9	3
513	B:B:D228	B:B:S227	4.42	Yes	No	0	9	6
514	B:B:I229	B:B:T243	6.08	No	Yes	2	7	8
515	B:B:D246	B:B:N230	8.08	No	No	0	9	9
516	B:B:A231	B:B:V276	3.39	No	No	0	5	6
517	B:B:F241	B:B:I232	5.02	Yes	Yes	2	6	8
518	B:B:I232	B:B:T243	4.56	Yes	Yes	2	8	8
519	B:B:F235	B:B:P236	10.11	Yes	No	31	6	7
520	B:B:F235	B:B:N237	7.25	Yes	No	0	6	5
521	B:B:F235	B:B:F278	9.65	Yes	Yes	0	6	7
522	B:B:F235	B:B:G282	4.52	Yes	No	31	6	9
523	B:B:F235	G:G:L37	4.87	Yes	No	0	6	7
524	B:B:G282	B:B:P236	4.06	No	No	31	9	7
525	B:B:P236	G:G:Y40	6.95	No	No	0	7	6
526	B:B:N237	B:B:N239	10.9	No	No	0	5	2
527	B:B:N237	G:G:Y40	5.81	No	No	0	5	6
528	B:B:N239	B:B:R256	10.85	No	Yes	0	2	9
529	B:B:F241	B:B:F253	10.72	Yes	Yes	2	6	6
530	B:B:A242	B:B:F278	4.16	No	Yes	0	4	7
531	B:B:F253	B:B:T243	7.78	Yes	Yes	2	6	8
532	B:B:G244	B:B:I273	3.53	No	No	0	5	6
533	B:B:D247	B:B:S245	10.31	Yes	No	2	9	9
534	B:B:D247	B:B:T249	10.12	Yes	No	0	9	6
535	B:B:R251	B:B:T249	5.17	Yes	No	0	8	6
536	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
537	B:B:C250	B:B:I273	6.55	No	No	0	8	6
538	B:B:F253	B:B:R251	3.21	Yes	Yes	2	6	8
539	B:B:E260	B:B:R251	12.79	Yes	Yes	2	6	8
540	B:B:R251	B:B:T263	12.94	Yes	No	2	8	1
541	B:B:L252	B:B:Y264	7.03	No	Yes	0	7	5
542	B:B:E260	B:B:F253	5.83	Yes	Yes	2	6	6
543	B:B:D254	B:B:R256	4.76	No	Yes	0	9	9
544	B:B:D254	B:B:L261	4.07	No	No	0	9	5
545	B:B:R256	G:G:I28	8.77	Yes	No	0	9	4
546	B:B:R256	G:G:D36	11.91	Yes	No	0	9	5
547	B:B:A257	B:B:Q259	4.55	No	Yes	0	7	6
548	B:B:D258	G:G:I25	5.6	Yes	No	2	7	2
549	B:B:D258	G:G:R27	5.96	Yes	Yes	2	7	8
550	B:B:Q259	G:G:V30	5.73	Yes	No	0	6	8
551	B:B:E260	B:B:T263	7.06	Yes	No	2	6	1
552	B:B:M262	B:B:Y264	10.78	Yes	Yes	0	4	5
553	B:B:A302	B:B:M262	4.83	No	Yes	0	2	4
554	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
555	B:B:W297	B:B:Y264	11.58	Yes	Yes	0	8	5
556	B:B:H266	B:B:I269	3.98	No	No	0	4	4
557	B:B:H266	B:B:R304	10.16	No	No	0	4	5
558	B:B:I269	B:B:Y289	7.25	No	Yes	0	4	7
559	B:B:C271	B:B:Y289	4.03	No	Yes	13	5	7
560	B:B:C271	B:B:D291	6.22	No	No	13	5	8
561	B:B:D290	B:B:G272	5.03	Yes	No	0	6	4
562	B:B:I273	B:B:Y289	10.88	No	Yes	0	6	7
563	B:B:D290	B:B:T274	5.78	Yes	No	1	6	8
564	B:B:R314	B:B:T274	6.47	Yes	No	1	8	8
565	B:B:L318	B:B:S275	6.01	No	No	0	6	8
566	B:B:G319	B:B:S277	3.71	No	Yes	0	5	5
567	B:B:S277	B:B:V320	4.85	Yes	No	0	5	7
568	B:B:F278	B:B:L285	7.31	Yes	No	0	7	6
569	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
570	B:B:G324	B:B:K280	3.49	No	No	0	9	1
571	B:B:S281	G:G:D48	8.83	No	Yes	0	9	9
572	B:B:D298	B:B:R283	14.29	No	Yes	29	9	9
573	B:B:L300	B:B:R283	10.93	No	Yes	0	6	9
574	B:B:R283	G:G:L51	4.86	Yes	Yes	0	9	6
575	B:B:L284	B:B:V296	5.96	No	No	0	5	5
576	B:B:L284	G:G:L51	4.15	No	Yes	0	5	6
577	B:B:L286	B:B:V296	4.47	No	No	0	7	5
578	B:B:L286	B:B:V327	5.96	No	No	0	7	6
579	B:B:A287	B:B:Y289	4	No	Yes	0	6	7
580	B:B:G288	B:B:V315	3.68	No	Yes	0	7	7
581	B:B:D291	B:B:Y289	3.45	No	Yes	13	8	7
582	B:B:N295	B:B:Y289	15.12	Yes	Yes	13	6	7
583	B:B:W297	B:B:Y289	4.82	Yes	Yes	13	8	7
584	B:B:D290	B:B:R314	13.1	Yes	Yes	1	6	8
585	B:B:D291	B:B:N293	5.39	No	No	0	8	5
586	B:B:N293	B:B:V307	4.43	No	No	0	5	3
587	B:B:A309	B:B:N293	4.69	No	No	0	3	5
588	B:B:C294	B:B:L308	4.76	No	No	0	5	7
589	B:B:C294	B:B:V315	5.12	No	Yes	0	5	7
590	B:B:C294	B:B:T329	3.38	No	No	0	5	8
591	B:B:N295	B:B:W297	3.39	Yes	Yes	13	6	8
592	B:B:N295	B:B:R304	7.23	Yes	No	13	6	5
593	B:B:N295	B:B:V307	4.43	Yes	No	0	6	3
594	B:B:R304	B:B:W297	5	No	Yes	13	5	8
595	B:B:D298	B:B:K301	5.53	No	No	0	9	5
596	B:B:L300	G:G:M38	4.24	No	No	0	6	4
597	B:B:L300	G:G:C41	6.35	No	No	0	6	7
598	B:B:L308	B:B:W339	11.39	No	Yes	9	7	9
599	B:B:A309	R:R:R419	5.53	No	No	0	3	7
600	B:B:G310	R:R:R419	7.51	No	No	0	5	7
601	B:B:H311	B:B:V315	4.15	Yes	Yes	9	9	7
602	B:B:H311	B:B:T329	8.21	Yes	No	0	9	8
603	B:B:H311	B:B:S331	12.55	Yes	No	9	9	9
604	B:B:D333	B:B:H311	7.56	Yes	Yes	9	9	9
605	B:B:H311	B:B:K337	13.1	Yes	Yes	9	9	6
606	B:B:D312	B:B:D333	6.65	No	Yes	0	5	9
607	B:B:D312	R:R:H171	23.95	No	No	0	5	7
608	B:B:D312	R:R:K415	5.53	No	No	0	5	7
609	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
610	B:B:R314	B:B:W332	18.99	Yes	Yes	1	8	9
611	B:B:S331	B:B:V315	3.23	No	Yes	9	9	7
612	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
613	B:B:D323	B:B:T321	7.23	No	No	30	7	7
614	B:B:D323	B:B:M325	4.16	No	No	0	7	5
615	B:B:G324	G:G:P49	4.06	No	No	0	9	7
616	B:B:M325	G:G:P49	5.03	No	No	0	5	7
617	B:B:M325	G:G:P60	3.35	No	Yes	0	5	9
618	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
619	B:B:V327	G:G:L50	4.47	No	No	0	6	9
620	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
621	B:B:G330	B:B:L336	3.42	No	Yes	0	5	7
622	B:B:D333	B:B:S331	7.36	Yes	No	9	9	9
623	B:B:D333	B:B:F335	8.36	Yes	No	0	9	4
624	B:B:F335	B:B:S334	5.28	No	No	0	4	4
625	B:B:K337	B:B:W339	10.44	Yes	Yes	9	6	9
626	B:B:I338	G:G:F61	5.02	Yes	Yes	8	5	8
627	B:B:N340	G:G:N59	13.62	No	Yes	0	9	9
628	B:B:N340	G:G:F61	3.62	No	Yes	0	9	8
629	G:G:E22	G:G:Q18	10.19	No	No	0	9	9
630	G:G:I25	G:G:R27	12.53	No	Yes	2	2	8
631	G:G:I28	G:G:K32	4.36	No	No	0	4	5
632	G:G:H44	G:G:Y40	21.78	No	No	0	6	6
633	G:G:E47	G:G:H44	3.69	No	No	0	3	6
634	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
635	G:G:D48	G:G:L51	5.43	Yes	Yes	0	9	6
636	G:G:P55	G:G:V54	3.53	No	No	0	5	6
637	G:G:N59	G:G:V54	4.43	Yes	No	0	9	6
638	G:G:N59	G:G:P60	4.89	Yes	Yes	0	9	9
639	G:G:F61	G:G:P60	4.33	Yes	Yes	8	8	9
640	L:L:E9	R:R:Y148	3.37	No	Yes	0	0	7
641	L:L:D15	L:L:T11	4.34	No	Yes	0	0	0
642	L:L:T11	R:R:L141	16.21	Yes	No	0	0	5
643	L:L:T11	R:R:Y145	3.75	Yes	Yes	0	0	5
644	L:L:F12	L:L:V16	3.93	Yes	No	0	0	0
645	L:L:F12	R:R:Y145	7.22	Yes	Yes	32	0	5
646	L:L:F12	R:R:D198	5.97	Yes	No	32	0	7
647	L:L:F12	R:R:L201	3.65	Yes	No	0	0	7
648	L:L:F12	R:R:K202	9.93	Yes	No	0	0	4
649	L:L:T13	R:R:S31	9.59	No	No	0	0	4
650	L:L:S17	R:R:L32	7.51	No	No	0	0	4
651	L:L:S17	R:R:T35	6.4	No	No	0	0	5
652	L:L:Y19	R:R:Y205	5.96	No	No	0	0	3
653	L:L:L20	R:R:L32	4.15	No	No	0	0	4
654	L:L:E21	R:R:L89	13.25	Yes	No	4	0	5
655	L:L:E21	R:R:P90	7.86	Yes	No	0	0	4
656	L:L:E21	R:R:W91	5.45	Yes	Yes	4	0	4
657	L:L:E27	L:L:Q23	3.82	No	No	33	0	0
658	L:L:Q23	R:R:Q211	6.4	No	No	33	0	4
659	L:L:Q23	R:R:W214	8.76	No	No	0	0	1
660	L:L:E27	L:L:F28	3.5	No	No	0	0	0
661	L:L:E27	R:R:Q211	19.11	No	No	33	0	4
662	L:L:F28	R:R:E68	7	No	No	0	0	4
663	L:L:F28	R:R:W214	5.01	No	No	0	0	1
664	L:L:I29	R:R:L118	5.71	No	No	0	0	4
665	R:R:S31	R:R:W33	4.94	No	Yes	20	4	3
666	R:R:E34	R:R:S31	5.75	Yes	No	20	4	4
667	R:R:E34	R:R:W33	3.27	Yes	Yes	20	4	3
668	R:R:W33	R:R:Y220	12.54	Yes	No	0	3	3
669	R:R:T298	R:R:W33	12.13	No	Yes	20	5	3
670	R:R:E34	R:R:T298	8.47	Yes	No	20	4	5
671	R:R:E34	R:R:R299	4.65	Yes	No	0	4	4
672	R:R:P90	R:R:T35	8.74	No	No	0	4	5
673	R:R:V36	R:R:Y220	12.62	No	No	0	2	3
674	R:R:Q37	R:R:R40	5.84	No	No	0	4	2
675	R:R:Q37	R:R:Y220	4.51	No	No	0	4	3
676	R:R:E294	R:R:Q37	6.37	No	No	0	4	4
677	R:R:R43	R:R:W39	8	Yes	No	0	4	5
678	R:R:W39	R:R:Y88	10.61	No	Yes	0	5	5
679	R:R:E41	R:R:Q45	6.37	No	No	0	4	5
680	R:R:E41	R:R:W87	3.27	No	No	0	4	3
681	R:R:R43	R:R:Y42	10.29	Yes	Yes	4	4	6
682	R:R:C46	R:R:Y42	8.06	Yes	Yes	4	8	6
683	R:R:W87	R:R:Y42	8.68	No	Yes	0	3	6
684	R:R:Y42	R:R:Y88	13.9	Yes	Yes	4	6	5
685	R:R:C46	R:R:R43	9.75	Yes	Yes	4	8	4
686	R:R:Q47	R:R:R43	9.35	No	Yes	4	3	4
687	R:R:F66	R:R:R43	18.17	No	Yes	4	7	4
688	R:R:C71	R:R:R43	5.57	No	Yes	4	9	4
689	R:R:Q45	R:R:R44	3.5	No	No	0	5	3
690	R:R:Q47	R:R:R44	3.5	No	No	0	3	3
691	R:R:Q45	R:R:R48	4.67	No	No	0	5	4
692	R:R:C46	R:R:S49	3.44	Yes	No	0	8	2
693	R:R:C46	R:R:C71	5.46	Yes	No	4	8	9
694	R:R:F66	R:R:Q47	15.23	No	No	4	7	3
695	R:R:E52	R:R:R48	16.28	No	No	0	2	4
696	R:R:L50	R:R:R64	9.72	No	No	0	4	4
697	R:R:D53	R:R:P54	4.83	No	No	0	3	2
698	R:R:D53	R:R:R64	3.57	No	No	0	3	4
699	R:R:P56	R:R:T58	3.5	No	No	0	1	1
700	R:R:D74	R:R:P56	4.83	Yes	No	0	3	1
701	R:R:F61	R:R:T58	6.49	No	No	0	3	1
702	R:R:D59	R:R:L60	16.29	No	No	0	3	1
703	R:R:D74	R:R:F61	14.33	Yes	No	0	3	3
704	R:R:C104	R:R:C62	7.28	No	No	0	9	9
705	R:R:C62	R:R:W110	6.53	No	No	0	9	9
706	R:R:P73	R:R:R64	4.32	No	No	0	5	4
707	R:R:T65	R:R:W72	4.85	No	Yes	0	5	9
708	R:R:D67	R:R:W72	4.47	No	Yes	0	9	9
709	R:R:P86	R:R:Y69	13.91	Yes	Yes	4	8	6
710	R:R:Y69	R:R:Y88	3.97	Yes	Yes	4	6	5
711	R:R:E127	R:R:Y69	3.37	No	Yes	0	2	6
712	R:R:R102	R:R:W72	24.99	Yes	Yes	10	8	9
713	R:R:P119	R:R:W72	5.4	No	Yes	10	6	9
714	R:R:L123	R:R:W72	9.11	No	Yes	10	5	9
715	R:R:D74	R:R:G75	5.03	Yes	No	0	3	7
716	R:R:E76	R:R:S79	4.31	No	No	0	1	5
717	R:R:F103	R:R:F80	3.22	Yes	No	0	4	4
718	R:R:H99	R:R:N82	16.58	Yes	No	0	4	4
719	R:R:H99	R:R:S84	6.97	Yes	No	0	4	4
720	R:R:C126	R:R:C85	7.28	No	No	4	9	9
721	R:R:P86	R:R:Y88	6.95	Yes	Yes	4	8	5
722	R:R:C126	R:R:P86	3.77	No	Yes	4	9	8
723	R:R:L89	R:R:Y88	10.55	No	Yes	4	5	5
724	R:R:L89	R:R:W91	7.97	No	Yes	4	5	4
725	R:R:E127	R:R:W91	3.27	No	Yes	0	2	4
726	R:R:K130	R:R:W91	4.64	No	Yes	0	1	4
727	R:R:K130	R:R:S94	6.12	No	No	0	1	4
728	R:R:P96	R:R:V95	3.53	No	No	0	3	5
729	R:R:E128	R:R:V95	5.7	No	No	0	3	5
730	R:R:E125	R:R:V100	7.13	No	Yes	0	5	7
731	R:R:R102	R:R:W110	10	Yes	No	10	8	9
732	R:R:R102	R:R:W120	4	Yes	Yes	10	8	5
733	R:R:D122	R:R:R102	13.1	No	Yes	10	7	8
734	R:R:F103	R:R:W120	9.02	Yes	Yes	10	4	5
735	R:R:F103	R:R:R121	7.48	Yes	No	10	4	6
736	R:R:E107	R:R:T105	15.52	No	No	0	5	4
737	R:R:E107	R:R:L109	5.3	No	No	0	5	5
738	R:R:W110	R:R:W120	8.43	No	Yes	10	9	5
739	R:R:L111	R:R:W120	19.36	No	Yes	0	4	5
740	R:R:N115	R:R:Q112	3.96	No	No	0	4	3
741	R:R:L118	R:R:P119	8.21	No	No	0	4	6
742	R:R:L123	R:R:P119	3.28	No	No	10	5	6
743	R:R:R121	R:R:W120	8	No	Yes	10	6	5
744	R:R:D122	R:R:W120	5.58	No	Yes	10	7	5
745	R:R:D122	R:R:R121	11.91	No	No	10	7	6
746	R:R:P137	R:R:S136	3.56	No	No	0	3	1
747	R:R:E139	R:R:F143	5.83	No	No	0	2	4
748	R:R:Q140	R:R:R380	3.5	No	Yes	0	4	5
749	R:R:F143	R:R:I147	3.77	No	No	0	4	6
750	R:R:L144	R:R:L384	4.15	No	No	0	6	5
751	R:R:L144	R:R:L388	4.15	No	No	0	6	7
752	R:R:I146	R:R:Y145	3.63	No	Yes	0	4	5
753	R:R:T149	R:R:Y145	8.74	No	Yes	0	7	5
754	R:R:D198	R:R:Y145	4.6	No	Yes	32	7	5
755	R:R:Y148	R:R:Y152	15.89	Yes	Yes	19	7	7
756	R:R:V194	R:R:Y148	3.79	No	Yes	19	7	7
757	R:R:L388	R:R:Y148	7.03	No	Yes	0	7	7
758	R:R:S392	R:R:Y148	6.36	No	Yes	19	9	7
759	R:R:G151	R:R:S392	3.71	No	No	0	8	9
760	R:R:F393	R:R:G151	9.03	No	No	0	7	8
761	R:R:R190	R:R:Y152	4.12	Yes	Yes	0	8	7
762	R:R:A191	R:R:Y152	4	No	Yes	0	7	7
763	R:R:V194	R:R:Y152	5.05	No	Yes	19	7	7
764	R:R:S392	R:R:Y152	8.9	No	Yes	19	9	7
765	R:R:G395	R:R:S155	3.71	No	No	0	9	9
766	R:R:F156	R:R:V160	3.93	No	No	0	7	3
767	R:R:F156	R:R:I188	6.28	No	No	0	7	7
768	R:R:F156	R:R:L192	3.65	No	No	0	7	3
769	R:R:F184	R:R:L159	4.87	Yes	Yes	0	8	9
770	R:R:F187	R:R:L159	3.65	Yes	Yes	34	8	9
771	R:R:I188	R:R:L159	4.28	No	Yes	0	7	9
772	R:R:G395	R:R:L159	5.13	No	Yes	34	9	9
773	R:R:F404	R:R:I161	3.77	No	No	0	8	4
774	R:R:A162	R:R:F184	4.16	No	Yes	0	9	8
775	R:R:A162	R:R:C403	3.61	No	No	0	9	9
776	R:R:F184	R:R:S163	3.96	Yes	No	0	8	6
777	R:R:C403	R:R:I165	3.27	No	No	0	9	8
778	R:R:F413	R:R:I165	7.54	No	No	0	5	8
779	R:R:L166	R:R:N177	4.12	Yes	No	0	8	9
780	R:R:L166	R:R:L181	6.92	Yes	No	0	8	6
781	R:R:F184	R:R:L166	4.87	Yes	Yes	0	8	8
782	R:R:C403	R:R:L166	4.76	No	Yes	0	9	8
783	R:R:L167	R:R:L181	5.54	No	No	0	3	6
784	R:R:F169	R:R:L172	3.65	Yes	No	35	7	9
785	R:R:E412	R:R:F169	8.16	Yes	Yes	35	8	7
786	R:R:F169	R:R:F413	7.5	Yes	No	0	7	5
787	R:R:E412	R:R:H171	13.54	Yes	No	0	8	7
788	R:R:L172	R:R:V409	4.47	No	No	0	9	9
789	R:R:E412	R:R:L172	3.98	Yes	No	35	8	9
790	R:R:H173	R:R:Y178	8.71	No	No	0	7	6
791	R:R:C174	R:R:R176	4.18	No	Yes	28	8	9
792	R:R:C174	R:R:N177	4.72	No	No	28	8	9
793	R:R:T175	R:R:Y250	4.99	No	Yes	0	7	8
794	R:R:N177	R:R:R176	3.62	No	Yes	28	9	9
795	R:R:H180	R:R:R176	5.64	No	Yes	0	9	9
796	R:R:E408	R:R:R176	5.82	No	Yes	0	9	9
797	R:R:F266	R:R:Y178	6.19	No	No	0	6	6
798	R:R:E247	R:R:I179	6.83	Yes	No	0	9	8
799	R:R:I179	R:R:Y250	6.04	No	Yes	0	8	8
800	R:R:E247	R:R:H180	11.08	Yes	No	0	9	9
801	R:R:H180	R:R:Y402	5.44	No	Yes	0	9	8
802	R:R:N182	R:R:W243	15.82	No	Yes	21	9	9
803	R:R:N182	R:R:W274	5.65	No	Yes	21	9	9
804	R:R:F187	R:R:L183	6.09	Yes	No	0	8	9
805	R:R:L183	R:R:L244	4.15	No	No	0	9	9
806	R:R:E247	R:R:L183	3.98	Yes	No	0	9	9
807	R:R:F184	R:R:V398	3.93	Yes	No	0	8	9
808	R:R:N240	R:R:S186	5.96	No	No	0	9	9
809	R:R:S186	R:R:W243	7.41	No	Yes	21	9	9
810	R:R:S186	R:R:W274	4.94	No	Yes	21	9	9
811	R:R:F187	R:R:N240	16.92	Yes	No	0	8	9
812	R:R:F187	R:R:Q394	12.88	Yes	Yes	0	8	9
813	R:R:F187	R:R:G395	6.02	Yes	No	34	8	9
814	R:R:R190	R:R:V237	7.85	Yes	No	0	8	6
815	R:R:N240	R:R:R190	9.64	No	Yes	0	9	8
816	R:R:R190	R:R:Y241	8.23	Yes	Yes	0	8	8
817	R:R:M233	R:R:S193	7.67	No	No	0	6	6
818	R:R:C236	R:R:S193	5.16	No	No	0	5	6
819	R:R:K202	R:R:Y205	7.17	No	No	0	4	3
820	R:R:T207	R:R:W203	3.64	No	No	0	3	3
821	R:R:G216	R:R:M204	3.49	No	No	0	2	3
822	R:R:Q210	R:R:Q213	10.24	No	No	0	4	4
823	R:R:H212	R:R:Q213	6.18	No	No	0	3	4
824	R:R:S219	R:R:S225	6.52	No	No	0	5	3
825	R:R:Q221	R:R:S223	8.66	No	No	0	4	4
826	R:R:D222	R:R:R227	4.76	Yes	No	16	6	8
827	R:R:D222	R:R:D293	5.32	Yes	No	0	6	7
828	R:R:D222	R:R:W297	6.7	Yes	Yes	16	6	8
829	R:R:L224	R:R:S223	4.5	No	No	0	3	4
830	R:R:C226	R:R:C296	7.28	No	Yes	0	9	9
831	R:R:L228	R:R:R227	7.29	No	No	0	4	8
832	R:R:R227	R:R:W297	5	No	Yes	16	8	8
833	R:R:F230	R:R:Q234	7.03	No	No	0	5	7
834	R:R:F230	R:R:W284	5.01	No	Yes	0	5	8
835	R:R:G285	R:R:L231	3.42	No	No	0	5	5
836	R:R:W274	R:R:Y235	6.75	Yes	No	0	9	9
837	R:R:P277	R:R:Y235	8.34	No	No	0	9	9
838	R:R:L278	R:R:Y235	7.03	No	No	0	3	9
839	R:R:I313	R:R:Y241	8.46	No	Yes	0	7	8
840	R:R:I317	R:R:Y241	4.84	No	Yes	0	7	8
841	R:R:E364	R:R:Y241	12.35	No	Yes	0	8	8
842	R:R:V276	R:R:Y242	7.57	No	No	0	3	6
843	R:R:F280	R:R:Y242	7.22	Yes	No	0	5	6
844	R:R:A316	R:R:Y242	9.34	No	No	0	7	6
845	R:R:V246	R:R:W243	8.58	No	Yes	0	8	9
846	R:R:G273	R:R:W243	7.04	No	Yes	0	9	9
847	R:R:W243	R:R:W274	24.37	Yes	Yes	21	9	9
848	R:R:L244	R:R:Q394	5.32	No	Yes	0	9	9
849	R:R:L245	R:R:V319	4.47	No	No	0	8	6
850	R:R:L245	R:R:N320	4.12	No	No	0	8	9
851	R:R:V246	R:R:Y269	3.79	No	Yes	0	8	7
852	R:R:E247	R:R:L359	9.28	Yes	No	0	9	9
853	R:R:V249	R:R:Y269	3.79	No	Yes	0	6	7
854	R:R:L254	R:R:Y250	15.24	No	Yes	0	8	8
855	R:R:Y250	R:R:Y269	9.93	Yes	Yes	0	8	7
856	R:R:L251	R:R:L255	5.54	No	Yes	27	9	8
857	R:R:L251	R:R:V327	4.47	No	No	27	9	9
858	R:R:A256	R:R:Y252	4	No	No	0	6	8
859	R:R:I323	R:R:Y252	4.84	No	No	0	8	8
860	R:R:R326	R:R:Y252	4.12	No	No	0	8	8
861	R:R:F257	R:R:T253	3.89	No	No	0	5	7
862	R:R:T253	R:R:Y269	4.99	No	Yes	0	7	7
863	R:R:L255	R:R:V327	4.47	Yes	No	27	8	9
864	R:R:I330	R:R:L255	4.28	No	Yes	0	9	8
865	R:R:I265	R:R:L260	4.28	No	No	0	5	7
866	R:R:Q263	R:R:S261	5.78	No	No	0	5	7
867	R:R:E262	R:R:Q263	15.29	No	No	0	6	5
868	R:R:I265	R:R:Y269	8.46	No	Yes	0	5	7
869	R:R:F266	R:R:V270	7.87	No	No	0	6	5
870	R:R:P277	R:R:V276	3.53	No	No	0	9	3
871	R:R:F280	R:R:P312	17.34	Yes	No	0	5	8
872	R:R:P283	R:R:V282	3.53	No	No	0	5	3
873	R:R:K288	R:R:W284	5.8	Yes	Yes	16	8	8
874	R:R:W284	R:R:W297	4.69	Yes	Yes	16	8	8
875	R:R:I308	R:R:W284	7.05	No	Yes	0	8	8
876	R:R:I309	R:R:W284	7.05	No	Yes	0	7	8
877	R:R:V287	R:R:Y305	5.05	No	No	0	4	4
878	R:R:E292	R:R:K288	8.1	No	Yes	0	6	8
879	R:R:K288	R:R:W297	16.24	Yes	Yes	16	8	8
880	R:R:K288	R:R:N300	4.2	Yes	No	0	8	6
881	R:R:L290	R:R:Y289	4.69	No	No	0	3	3
882	R:R:W297	R:R:Y289	3.86	Yes	No	0	8	3
883	R:R:Y291	R:R:Y305	8.94	No	No	0	3	4
884	R:R:E292	R:R:S301	8.62	No	No	0	6	3
885	R:R:C296	R:R:T298	3.38	Yes	No	0	9	5
886	R:R:N300	R:R:W306	5.65	No	No	0	6	6
887	R:R:N302	R:R:N304	5.45	No	No	0	5	3
888	R:R:N302	R:R:Y305	10.47	No	No	0	5	4
889	R:R:I309	R:R:W306	3.52	No	No	0	7	6
890	R:R:R310	R:R:W306	8	No	No	0	6	6
891	R:R:L307	R:R:L311	4.15	No	No	0	7	4
892	R:R:F315	R:R:V319	7.87	No	No	0	4	6
893	R:R:L360	R:R:N320	5.49	Yes	No	0	9	9
894	R:R:F321	R:R:V365	14.42	No	No	0	6	6
895	R:R:F324	R:R:T353	5.19	Yes	No	0	9	9
896	R:R:F324	R:R:L356	7.31	Yes	No	15	9	9
897	R:R:F324	R:R:I357	5.02	Yes	No	15	9	8
898	R:R:F324	R:R:L360	3.65	Yes	Yes	15	9	9
899	R:R:F324	R:R:T362	15.56	Yes	No	15	9	7
900	R:R:I330	R:R:R326	6.26	No	No	0	9	8
901	R:R:S352	R:R:V331	3.23	No	No	0	9	8
902	R:R:L349	R:R:V332	4.47	No	No	0	9	6
903	R:R:C347	R:R:T343	3.38	No	No	0	7	5
904	R:R:K351	R:R:R348	12.38	No	No	0	8	8
905	R:R:L356	R:R:L360	8.3	No	Yes	15	9	9
906	R:R:I357	R:R:P358	3.39	No	No	0	8	9
907	R:R:I357	R:R:T362	4.56	No	No	15	8	7
908	R:R:M397	R:R:P358	3.35	No	No	0	5	9
909	R:R:L401	R:R:P358	4.93	No	No	0	8	9
910	R:R:L359	R:R:L360	4.15	No	Yes	0	9	9
911	R:R:L359	R:R:Y402	19.93	No	Yes	0	9	8
912	R:R:G361	R:R:Q394	3.29	No	Yes	0	9	9
913	R:R:E364	R:R:H363	8.62	No	No	0	8	8
914	R:R:H363	R:R:Q394	8.65	No	Yes	0	8	9
915	R:R:F367	R:R:I366	5.02	Yes	No	0	7	6
916	R:R:F367	R:R:T386	5.19	Yes	No	0	7	4
917	R:R:E387	R:R:F367	17.49	No	Yes	0	8	7
918	R:R:F367	R:R:F390	5.36	Yes	No	0	7	6
919	R:R:A375	R:R:H374	7.32	No	No	36	4	3
920	R:R:H374	R:R:K383	10.48	No	No	36	3	7
921	R:R:A375	R:R:R380	4.15	No	Yes	0	4	5
922	R:R:A375	R:R:K383	4.82	No	No	36	4	7
923	R:R:G377	R:R:R376	4.5	No	No	0	4	5
924	R:R:R376	R:R:R380	4.26	No	Yes	0	5	5
925	R:R:L384	R:R:R380	8.5	No	Yes	0	5	5
926	R:R:F381	R:R:I382	3.77	No	No	0	4	4
927	R:R:E387	R:R:K383	4.05	No	No	0	8	7
928	R:R:F385	R:R:T386	3.89	No	No	0	6	4
929	R:R:I400	R:R:L396	5.71	No	No	0	6	7
930	R:R:F404	R:R:I400	3.77	No	No	0	8	6
931	R:R:L401	R:R:Y402	3.52	No	Yes	0	8	8
932	R:R:E408	R:R:N406	9.2	No	No	0	9	9
933	R:R:N406	R:R:V409	7.39	No	No	0	9	9
934	R:R:E412	R:R:K415	8.1	Yes	No	0	8	7
935	R:R:R414	R:R:W417	11	No	No	0	6	5
936	R:R:K415	R:R:R419	7.43	No	No	0	7	7
937	R:R:R421	R:R:W417	8	No	No	0	4	5
938	R:R:E423	R:R:W420	3.27	No	No	0	4	4
939	B:B:S265	B:B:T249	3.2	No	No	0	2	6
940	B:B:S265	B:B:T263	3.2	No	No	0	2	1
941	B:B:S275	B:B:T274	3.2	No	No	0	8	8
942	R:R:C71	R:R:L50	3.17	No	No	0	9	4
943	R:R:A399	R:R:L159	3.15	No	Yes	0	8	9
944	A:A:T204	B:B:T143	3.14	No	No	0	9	5
945	A:A:E314	A:A:P313	3.14	No	No	0	6	6
946	B:B:T177	B:B:T178	3.14	No	No	0	4	4
947	R:R:C296	R:R:D222	3.11	Yes	Yes	0	9	6
948	B:B:I33	G:G:S31	3.1	No	No	0	3	9
949	R:R:I147	R:R:S389	3.1	No	No	0	6	5
950	B:B:A193	B:B:D195	3.09	No	No	0	4	5
951	B:B:D254	G:G:A33	3.09	No	No	0	9	7
952	R:R:F195	R:R:Y152	3.09	No	Yes	0	7	7
953	B:B:M262	B:B:S31	3.07	Yes	No	0	4	1
954	R:R:I272	R:R:V246	3.07	Yes	No	0	6	8
955	R:R:I272	R:R:V276	3.07	Yes	No	0	6	3
956	R:R:I286	R:R:V287	3.07	No	No	0	4	4
957	B:B:I33	B:B:T34	3.04	No	Yes	0	3	5
958	R:R:I328	R:R:T353	3.04	No	No	0	7	9
959	R:R:I382	R:R:T386	3.04	No	No	0	4	4
960	B:B:A26	B:B:Q259	3.03	No	Yes	0	3	6
961	A:A:A14	A:A:E15	3.02	No	No	0	1	5
962	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
963	R:R:M204	R:R:T207	3.01	No	No	0	3	3
964	A:A:K17	A:A:T11	3	No	No	0	4	4
965	B:B:L4	G:G:S8	3	No	No	0	4	4
966	B:B:L286	B:B:S277	3	No	Yes	0	7	5
967	B:B:L318	B:B:S277	3	No	Yes	0	6	5
968	R:R:K342	R:R:T343	3	No	No	0	5	5
969	A:A:L388	R:R:V331	2.98	No	No	0	8	8
970	B:B:L210	B:B:V200	2.98	No	Yes	0	5	6
971	L:L:L20	L:L:V16	2.98	No	No	0	0	0
972	R:R:L32	R:R:V36	2.98	No	No	0	4	2
973	R:R:L228	R:R:V229	2.98	No	No	0	4	7
974	R:R:L231	R:R:V281	2.98	No	No	0	5	6
975	G:G:L51	G:G:T52	2.95	Yes	No	0	6	4
976	B:B:D246	B:B:S227	2.94	No	No	0	9	6
977	B:B:D247	B:B:S227	2.94	Yes	No	0	9	6
978	R:R:I161	R:R:I165	2.94	No	No	0	4	8
979	B:B:N125	B:B:T128	2.92	No	No	0	4	3
980	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
981	A:A:I26	A:A:L30	2.85	Yes	No	0	9	5
982	R:R:K113	R:R:L118	2.82	No	No	0	4	4
983	R:R:E364	R:R:T391	2.82	No	No	0	8	6
984	R:R:G285	R:R:W297	2.81	No	Yes	0	5	8
985	B:B:C233	B:B:F278	2.79	No	Yes	0	3	7
986	A:A:D310	A:A:K307	2.77	No	No	0	3	6
987	A:A:L394	R:R:L335	2.77	No	No	0	8	8
988	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
989	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
990	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
991	G:G:L15	G:G:L19	2.77	No	No	0	2	9
992	R:R:A153	R:R:F195	2.77	No	No	0	6	7
993	R:R:A238	R:R:F280	2.77	No	Yes	0	6	5
994	R:R:L307	R:R:N304	2.75	No	No	0	7	3
995	B:B:E138	B:B:I120	2.73	No	No	0	6	6
996	R:R:M233	R:R:Q234	2.72	No	No	0	6	7
997	L:L:E9	R:R:K197	2.7	No	No	0	0	6
998	A:A:Y37	B:B:A56	2.67	Yes	No	0	4	7
999	L:L:A25	R:R:Y69	2.67	No	Yes	0	0	6
1000	R:R:F393	R:R:S389	2.64	No	No	0	7	5
1001	B:B:E12	B:B:N16	2.63	No	No	0	4	1
1002	A:A:F238	A:A:V241	2.62	Yes	No	0	9	9
1003	B:B:R134	B:B:V135	2.62	No	Yes	0	3	4
1004	R:R:F280	R:R:V281	2.62	Yes	No	0	5	6
1005	R:R:F321	R:R:V325	2.62	No	No	0	6	5
1006	R:R:D215	R:R:Q213	2.61	No	No	0	3	4
1007	R:R:F103	R:R:T105	2.59	Yes	No	0	4	4
1008	R:R:A239	R:R:W274	2.59	No	Yes	0	8	9
1009	R:R:F321	R:R:T362	2.59	No	No	0	6	7
1010	A:A:S306	A:A:Y253	2.54	No	Yes	0	7	8
1011	B:B:S136	B:B:Y111	2.54	No	Yes	0	4	4
1012	A:A:I26	A:A:R22	2.51	Yes	No	0	9	5
1013	A:A:I62	A:A:R61	2.51	No	No	0	9	8
1014	A:A:I383	A:A:R380	2.51	No	No	0	8	7
1015	B:B:I123	B:B:R137	2.51	Yes	No	3	6	5
1016	B:B:I171	B:B:R137	2.51	Yes	No	3	6	5
1017	R:R:F266	R:R:I179	2.51	No	No	0	6	8
1018	A:A:T325	A:A:Y339	2.5	No	Yes	0	2	3
1019	R:R:T355	R:R:Y402	2.5	No	Yes	0	8	8
1020	R:R:H99	R:R:Q97	2.47	Yes	No	0	4	4
1021	R:R:S206	R:R:W203	2.47	No	No	0	4	3
1022	R:R:S261	R:R:W264	2.47	No	No	0	7	5
1023	R:R:L335	R:R:R348	2.43	No	No	0	8	8
1024	B:B:F292	B:B:N313	2.42	No	No	0	4	7
1025	R:R:F61	R:R:N63	2.42	No	No	0	3	4
1026	B:B:D20	B:B:R19	2.38	No	No	0	2	4
1027	B:B:Q44	B:B:R42	2.34	No	No	0	4	2
1028	R:R:L290	R:R:Y291	2.34	No	No	0	3	3
1029	R:R:E68	R:R:F66	2.33	No	No	0	4	7
1030	R:R:L189	R:R:W274	2.28	No	Yes	0	7	9
1031	R:R:G275	R:R:P277	2.03	No	No	0	6	9
1032	R:R:C85	R:R:G98	1.96	No	No	0	9	4
1033	R:R:C296	R:R:G295	1.96	Yes	No	0	9	4
1034	B:B:A140	B:B:G141	1.95	No	No	0	5	5
1035	R:R:P54	R:R:P55	1.95	No	No	0	2	1
1036	R:R:P55	R:R:P56	1.95	No	No	0	1	1
1037	B:B:A193	B:B:P194	1.87	No	No	0	4	4
1038	R:R:A70	R:R:P86	1.87	No	Yes	0	5	8
1039	R:R:G78	R:R:S79	1.86	No	No	0	7	5
1040	R:R:G216	R:R:S219	1.86	No	No	0	2	5
1041	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
1042	B:B:G244	B:B:V276	1.84	No	No	0	5	6
1043	R:R:G151	R:R:V150	1.84	No	No	0	8	5
1044	A:A:G52	A:A:T55	1.82	No	No	0	9	9
1045	B:B:G131	B:B:T128	1.82	No	No	0	4	3
1046	B:B:G174	B:B:T173	1.82	No	Yes	0	4	5
1047	B:B:G224	B:B:T223	1.82	No	No	0	6	2
1048	L:L:G10	L:L:T13	1.82	No	No	0	0	0
1049	B:B:A60	B:B:C103	1.81	No	No	0	7	8
1050	G:G:A10	G:G:A7	1.79	No	No	0	2	4
1051	R:R:A158	R:R:A399	1.79	No	No	0	7	8
1052	R:R:G248	R:R:I323	1.76	No	No	0	8	8
1053	R:R:G318	R:R:I317	1.76	No	No	0	4	7
1054	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1055	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1056	A:A:G304	A:A:K305	1.74	No	No	0	5	3
1057	A:A:A14	A:A:S13	1.71	No	No	0	1	7
1058	B:B:A28	G:G:S31	1.71	No	No	0	4	9
1059	R:R:C85	R:R:V100	1.71	No	Yes	4	9	7
1060	R:R:C126	R:R:V100	1.71	No	Yes	4	9	7
1061	R:R:G168	R:R:L167	1.71	No	No	0	1	3
1062	A:A:A337	A:A:V301	1.7	No	No	0	8	7
1063	B:B:A11	G:G:V16	1.7	No	No	0	5	7
1064	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
1065	R:R:A92	R:R:V95	1.7	No	No	0	5	5
1066	R:R:I308	R:R:P283	1.69	No	No	0	8	5
1067	A:A:E330	A:A:G329	1.64	Yes	No	0	3	7
1068	B:B:E260	B:B:G224	1.64	Yes	No	0	6	6
1069	L:L:E21	L:L:G22	1.64	Yes	No	0	0	0
1070	R:R:E107	R:R:G108	1.64	No	No	0	5	9
1071	R:R:C341	R:R:I345	1.64	No	No	0	4	5
1072	B:B:A248	B:B:I269	1.62	No	No	0	5	4
1073	B:B:D38	B:B:P39	1.61	No	No	0	1	1
1074	A:A:S54	A:A:T55	1.6	No	No	0	9	9
1075	B:B:S31	B:B:T29	1.6	No	No	0	1	3
1076	R:R:V100	R:R:V83	1.6	Yes	No	0	7	5
1077	A:A:T204	A:A:V202	1.59	No	No	0	9	6
1078	R:R:G98	R:R:H99	1.59	No	Yes	0	4	4
1079	B:B:L4	G:G:A12	1.58	No	No	0	4	5
1080	B:B:L14	G:G:A23	1.58	No	Yes	0	8	8
1081	B:B:A299	B:B:L285	1.58	No	No	0	5	6
1082	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
1083	L:L:L20	R:R:A208	1.58	No	No	0	0	4
1084	R:R:E76	R:R:P77	1.57	No	No	0	1	4
1085	A:A:A19	B:B:N88	1.56	No	Yes	0	4	7
1086	A:A:A48	A:A:N50	1.56	No	Yes	0	8	9
1087	G:G:A23	G:G:N24	1.56	Yes	No	0	8	1
1088	R:R:C62	R:R:D74	1.56	No	Yes	0	9	3
1089	R:R:C347	R:R:D344	1.56	No	No	0	7	7
1090	G:G:I9	G:G:S8	1.55	No	No	0	2	4
1091	R:R:I272	R:R:S271	1.55	Yes	No	0	6	3
1092	R:R:I400	R:R:V405	1.54	No	No	0	6	6
1093	A:A:K24	A:A:V20	1.52	No	No	0	4	3
1094	B:B:Q17	G:G:A23	1.52	No	Yes	0	4	8
1095	R:R:K336	R:R:V332	1.52	No	No	0	6	6
1096	L:L:A24	R:R:E68	1.51	No	No	0	0	4
1097	R:R:A368	R:R:E387	1.51	No	No	0	6	8
1098	R:R:L349	R:R:S352	1.5	No	No	0	9	9
1099	A:A:L302	A:A:V301	1.49	No	No	26	2	7
1100	A:A:L302	A:A:V334	1.49	No	Yes	26	2	4
1101	B:B:L7	G:G:V16	1.49	No	No	0	8	7
1102	B:B:L192	B:B:T196	1.47	No	No	0	5	1
1103	L:L:T11	R:R:L142	1.47	Yes	No	0	0	3
1104	L:L:D15	L:L:S14	1.47	No	No	0	0	0
1105	R:R:D114	R:R:S116	1.47	No	No	0	4	5
1106	A:A:N218	A:A:T40	1.46	No	No	0	4	7
1107	A:A:D196	A:A:V197	1.46	No	No	0	9	7
1108	G:G:A43	G:G:H44	1.46	No	No	0	4	6
1109	R:R:D59	R:R:T58	1.45	No	No	0	3	1
1110	A:A:K28	A:A:M25	1.44	No	No	0	4	4
1111	A:A:K28	A:A:K32	1.44	No	No	0	4	4
1112	L:L:E21	L:L:S18	1.44	Yes	No	0	0	0
1113	R:R:E127	R:R:S124	1.44	No	No	0	2	5
1114	R:R:E138	R:R:S136	1.44	No	No	0	2	1
1115	R:R:E139	R:R:S136	1.44	No	No	0	2	1
1116	R:R:I196	R:R:L192	1.43	No	No	0	5	3
1117	R:R:I272	R:R:L268	1.43	Yes	No	0	6	2
1118	R:R:I317	R:R:L314	1.43	No	No	0	7	4
1119	R:R:I345	R:R:L335	1.43	No	No	0	5	8
1120	R:R:Q410	R:R:V405	1.43	No	No	0	7	6
1121	A:A:E370	A:A:T369	1.41	No	No	0	4	9
1122	R:R:L339	R:R:M340	1.41	No	No	0	7	5
1123	R:R:K346	R:R:L349	1.41	No	No	0	6	9
1124	A:A:A316	A:A:R317	1.38	No	No	0	2	2
1125	A:A:R385	R:R:A337	1.38	Yes	No	0	5	7
1126	B:B:D303	B:B:K301	1.38	No	No	0	2	5
1127	R:R:L224	R:R:L228	1.38	No	No	0	3	4
1128	A:A:E21	A:A:K17	1.35	No	No	0	3	4
1129	R:R:L111	R:R:Q112	1.33	No	No	0	4	3
1130	R:R:L218	R:R:Q221	1.33	No	No	0	3	4
1131	A:A:N371	A:A:Q59	1.32	No	No	0	9	9
1132	B:B:N16	B:B:Q13	1.32	No	No	0	1	1
1133	R:R:F169	R:R:S416	1.32	Yes	No	0	7	5
1134	R:R:R102	R:R:V81	1.31	Yes	No	0	8	6
1135	A:A:D323	A:A:E322	1.3	No	No	0	4	1
1136	R:R:A185	R:R:W274	1.3	No	Yes	0	3	9
1137	B:B:H266	B:B:N268	1.28	No	No	0	4	4
1138	B:B:E3	B:B:Q6	1.27	No	No	0	5	1
1139	B:B:E12	B:B:Q9	1.27	No	No	0	4	3
1140	R:R:E125	R:R:E128	1.27	No	No	0	5	3
1141	A:A:I62	A:A:Y63	1.21	No	No	0	9	9
1142	G:G:N59	G:G:R62	1.21	Yes	No	0	9	7
1143	R:R:L217	R:R:R40	1.21	No	No	0	4	2
1144	B:B:Q6	G:G:R13	1.17	No	No	0	1	6
1145	B:B:Q9	B:B:R8	1.17	No	No	0	3	3
1146	R:R:N82	R:R:Y101	1.16	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:I26	3.2425	4	0	9
2	A:A:Y37	7.568	5	22	4
3	A:A:N50	8.01	4	18	9
4	A:A:S51	4.215	4	6	9
5	A:A:K53	5.5775	4	6	9
6	A:A:F208	6.35	4	23	5
7	A:A:F219	7.46667	6	11	8
8	A:A:H220	9.8925	4	17	7
9	A:A:M221	5.265	4	11	8
10	A:A:F222	10.03	4	17	7
11	A:A:Q227	5.454	5	1	9
12	A:A:K233	5.898	5	1	9
13	A:A:W234	6.93167	6	1	9
14	A:A:F238	8.216	5	0	9
15	A:A:D249	9.305	4	18	8
16	A:A:Y253	5.636	5	0	8
17	A:A:R265	8.9225	4	18	9
18	A:A:L270	5.4975	4	0	6
19	A:A:F273	6.6325	4	0	9
20	A:A:W277	9.8725	4	0	6
21	A:A:W281	10.7267	6	1	5
22	A:A:L289	4.945	4	0	9
23	A:A:F290	5.05833	6	6	9
24	A:A:Q294	8.6175	4	14	6
25	A:A:F312	5.4775	4	0	8
26	A:A:F315	10.985	4	24	6
27	A:A:Y318	6.78	4	0	6
28	A:A:P321	5.9075	4	0	5
29	A:A:E330	7.7	4	0	3
30	A:A:V334	3.805	4	26	4
31	A:A:Y339	6.1175	4	0	3
32	A:A:F340	8.425	4	0	7
33	A:A:R342	7.02	5	0	4
34	A:A:F345	8.6425	4	0	8
35	A:A:Y360	8.5275	4	12	8
36	A:A:F363	8.1775	4	14	5
37	A:A:T364	6.48	5	6	9
38	A:A:R374	8.15	6	6	4
39	A:A:F376	4.85	5	11	8
40	A:A:R385	7.02	4	12	5
41	A:A:Y391	6.7075	4	0	4
42	B:B:T34	4.8875	4	0	5
43	B:B:V40	4.71	4	29	3
44	B:B:H54	11.2125	4	0	9
45	B:B:K57	10.994	5	1	9
46	B:B:Y59	7.076	5	1	8
47	B:B:W63	6.52	5	0	7
48	B:B:Q75	10.38	4	1	9
49	B:B:D76	7.83	4	22	9
50	B:B:I81	5.45	4	5	7
51	B:B:W82	9.812	5	8	9
52	B:B:N88	5.92	4	0	7
53	B:B:K89	6.0175	4	0	9
54	B:B:H91	6.3725	4	5	5
55	B:B:L95	4.9025	4	0	8
56	B:B:W99	9.02167	6	0	9
57	B:B:Y105	4.3625	8	5	6
58	B:B:N110	5.8175	4	3	4
59	B:B:Y111	6.796	5	3	4
60	B:B:V112	4.13	4	5	8
61	B:B:C114	4.7725	4	5	8
62	B:B:I123	4.854	5	3	6
63	B:B:Y124	5.288	5	5	6
64	B:B:L126	4.3525	4	5	5
65	B:B:V135	4.295	4	5	4
66	B:B:H142	7.68833	6	3	9
67	B:B:Y145	7.20333	6	1	8
68	B:B:F151	4.73429	7	3	9
69	B:B:Q156	6.425	4	0	5
70	B:B:I157	4.6875	4	3	7
71	B:B:T159	7.1925	4	3	9
72	B:B:D163	8.795	4	3	9
73	B:B:W169	8.94	6	3	8
74	B:B:I171	4.8825	4	3	6
75	B:B:T173	5.4575	4	0	5
76	B:B:Q176	8.3225	4	3	4
77	B:B:F180	7.93	4	7	7
78	B:B:H183	9.166	5	7	9
79	B:B:V187	5.088	5	7	9
80	B:B:F199	8.1	4	7	9
81	B:B:V200	7.9075	4	2	6
82	B:B:S201	5.2625	4	7	9
83	B:B:K209	9.808	5	7	6
84	B:B:W211	9.362	5	7	8
85	B:B:F222	8.36	4	2	8
86	B:B:H225	10.986	5	2	9
87	B:B:D228	8.83	4	1	9
88	B:B:I232	5.475	4	2	8
89	B:B:F235	6.52833	6	31	6
90	B:B:F241	7.584	5	2	6
91	B:B:T243	6.6575	4	2	8
92	B:B:D247	7.218	5	2	9
93	B:B:R251	9.756	5	2	8
94	B:B:F253	6.794	5	2	6
95	B:B:R256	9.0725	4	0	9
96	B:B:D258	8.022	5	2	7
97	B:B:Q259	4.2025	4	0	6
98	B:B:E260	6.83	4	2	6
99	B:B:M262	6.4375	4	0	4
100	B:B:Y264	7.622	5	0	5
101	B:B:S277	3.64	4	0	5
102	B:B:F278	5.9775	4	0	7
103	B:B:R283	9.155	4	29	9
104	B:B:Y289	7.07857	7	13	7
105	B:B:D290	7.6525	4	1	6
106	B:B:N295	7.5425	4	13	6
107	B:B:W297	6.1975	4	13	8
108	B:B:H311	9.114	5	9	9
109	B:B:R314	14.18	5	1	8
110	B:B:V315	4.045	4	9	7
111	B:B:W332	9.96143	7	1	9
112	B:B:D333	7.4825	4	9	9
113	B:B:L336	4.248	5	8	7
114	B:B:K337	9.64	4	9	6
115	B:B:I338	4.7525	4	8	5
116	B:B:W339	8.944	5	9	9
117	G:G:A23	1.9775	4	0	8
118	G:G:R27	6.705	4	2	8
119	G:G:D48	6.98	4	0	9
120	G:G:L51	3.794	5	0	6
121	G:G:N59	6.0375	4	0	9
122	G:G:P60	6.9675	4	8	9
123	G:G:F61	5.14857	7	8	8
124	L:L:T11	6.4425	4	0	0
125	L:L:F12	6.14	5	32	0
126	L:L:E21	5.928	5	4	0
127	R:R:W33	8.22	4	20	3
128	R:R:E34	5.535	4	20	4
129	R:R:Y42	10.2325	4	4	6
130	R:R:R43	10.1883	6	4	4
131	R:R:C46	6.6775	4	4	8
132	R:R:Y69	5.98	4	4	6
133	R:R:W72	9.764	5	10	9
134	R:R:D74	6.4375	4	0	3
135	R:R:P86	6.625	4	4	8
136	R:R:Y88	9.196	5	4	5
137	R:R:W91	5.3325	4	4	4
138	R:R:H99	6.9025	4	0	4
139	R:R:V100	3.0375	4	4	7
140	R:R:R102	10.68	5	10	8
141	R:R:F103	5.5775	4	10	4
142	R:R:W120	9.065	6	10	5
143	R:R:Y145	5.588	5	32	5
144	R:R:Y148	7.288	5	19	7
145	R:R:Y152	6.84167	6	19	7
146	R:R:L159	4.216	5	34	9
147	R:R:L166	5.1675	4	0	8
148	R:R:F169	5.1575	4	35	7
149	R:R:R176	5.70333	6	28	9
150	R:R:F184	4.358	5	0	8
151	R:R:F187	9.112	5	34	8
152	R:R:R190	7.46	4	0	8
153	R:R:D222	4.9725	4	16	6
154	R:R:Y241	8.47	4	0	8
155	R:R:W243	12.644	5	21	9
156	R:R:E247	6.908	5	0	9
157	R:R:Y250	8.232	5	0	8
158	R:R:L255	5.3025	4	27	8
159	R:R:Y269	6.192	5	0	7
160	R:R:I272	2.28	4	0	6
161	R:R:W274	6.84	7	21	9
162	R:R:F280	7.4875	4	0	5
163	R:R:W284	5.92	5	16	8
164	R:R:K288	8.585	4	16	8
165	R:R:C296	3.9325	4	0	9
166	R:R:W297	6.55	6	16	8
167	R:R:F324	7.346	5	15	9
168	R:R:K334	7.015	4	12	9
169	R:R:L360	5.3975	4	15	9
170	R:R:F367	8.265	4	0	7
171	R:R:R380	5.1025	4	0	5
172	R:R:Q394	7.535	4	0	9
173	R:R:Y402	7.8475	4	0	8
174	R:R:E412	8.445	4	35	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:Y37	B:B:D76	12.8123	3.45	Yes	Yes	22	4	9
2	A:A:R42	A:A:Y37	17.7806	19.55	No	Yes	0	9	4
3	A:A:F222	A:A:R42	18.0393	3.21	Yes	No	0	7	9
4	B:B:R68	B:B:Y85	21.6308	28.81	No	No	0	5	4
5	B:B:Y85	G:G:P60	21.5096	15.3	No	Yes	8	4	9
6	B:B:M325	G:G:P60	28.0701	3.35	No	Yes	0	5	9
7	B:B:M325	G:G:P49	29.4379	5.03	No	No	0	5	7
8	G:G:D48	G:G:P49	29.8458	4.83	Yes	No	0	9	7
9	G:G:D48	G:G:L51	30.2567	5.43	Yes	Yes	0	9	6
10	B:B:L284	G:G:L51	31.8397	4.15	No	Yes	0	5	6
11	B:B:L284	B:B:V296	32.1031	5.96	No	No	0	5	5
12	B:B:L286	B:B:V296	32.2381	4.47	No	No	0	7	5
13	B:B:L286	B:B:V327	98.7883	5.96	No	No	0	7	6
14	B:B:V327	G:G:L50	98.8799	4.47	No	No	0	6	9
15	B:B:M45	G:G:L50	98.9729	5.65	No	No	0	4	9
16	B:B:M45	B:B:W339	98.904	3.49	No	Yes	9	4	9
17	B:B:T329	B:B:W339	49.4687	9.7	No	Yes	0	8	9
18	B:B:H311	B:B:T329	49.6342	8.21	Yes	No	0	9	8
19	B:B:D333	B:B:H311	99.4668	7.56	Yes	Yes	9	9	9
20	B:B:D312	B:B:D333	100	6.65	No	Yes	0	5	9
21	B:B:D312	R:R:H171	49.7972	23.95	No	No	0	5	7
22	R:R:E412	R:R:H171	49.7616	13.54	Yes	No	0	8	7
23	R:R:E412	R:R:L172	81.3212	3.98	Yes	No	35	8	9
24	R:R:L172	R:R:V409	81.2609	4.47	No	No	0	9	9
25	R:R:N406	R:R:V409	81.1515	7.39	No	No	0	9	9
26	R:R:E408	R:R:N406	80.8231	9.2	No	No	0	9	9
27	R:R:E408	R:R:R176	80.714	5.82	No	Yes	0	9	9
28	A:A:Y391	R:R:R176	73.8482	10.29	Yes	Yes	0	4	9
29	A:A:Y391	R:R:L251	29.9996	8.21	Yes	No	0	4	9
30	R:R:L251	R:R:L255	29.6916	5.54	No	Yes	27	9	8
31	A:A:L388	R:R:L255	28.6464	6.92	No	Yes	0	8	8
32	A:A:L388	A:A:L394	27.5893	4.15	No	No	0	8	8
33	A:A:L394	R:R:K334	26.68	4.23	No	Yes	0	8	9
34	A:A:D381	R:R:K334	25.5818	6.91	No	Yes	12	8	9
35	A:A:D381	A:A:Y360	25.4629	10.34	No	Yes	12	8	8
36	A:A:D378	A:A:Y360	25.0051	11.49	No	Yes	0	7	8
37	A:A:D378	A:A:I288	10.3552	12.59	No	No	0	7	9
38	A:A:F290	A:A:I288	10.0426	3.77	Yes	No	0	9	9
39	B:B:K337	B:B:W339	49.6349	10.44	Yes	Yes	9	6	9
40	B:B:H311	B:B:K337	49.6351	13.1	Yes	Yes	9	9	6
41	B:B:D312	R:R:K415	50.2136	5.53	No	No	0	5	7
42	R:R:E412	R:R:K415	54.0584	8.1	Yes	No	0	8	7
43	A:A:D378	A:A:H362	14.4972	10.08	No	No	0	7	9
44	A:A:F290	A:A:H362	10.0392	7.92	Yes	No	6	9	9
45	A:A:F222	B:B:W99	20.4507	23.05	Yes	Yes	0	7	9
46	B:B:L69	B:B:Y105	19.4233	3.52	No	Yes	0	5	6
47	B:B:D66	B:B:L69	19.4945	9.5	No	No	0	8	5
48	B:B:D66	B:B:R68	19.6036	3.57	No	No	0	8	5
49	A:A:K233	B:B:D228	29.954	6.91	Yes	Yes	1	9	9
50	A:A:K233	A:A:Q236	26.6282	4.07	Yes	No	1	9	8
51	B:B:Q75	B:B:W99	14.9313	6.57	Yes	Yes	0	9	9
52	B:B:R314	B:B:W332	13.548	18.99	Yes	Yes	1	8	9
53	A:A:Q236	B:B:R314	25.7229	9.35	No	Yes	1	8	8
54	A:A:R280	A:A:W281	34.9204	17.99	No	Yes	0	5	5
55	A:A:R280	A:A:R283	34.6215	4.26	No	No	0	5	3
56	A:A:R283	A:A:R356	34.3225	8.53	No	No	0	3	2
57	A:A:H357	A:A:R356	33.425	6.77	No	No	0	7	2
58	A:A:H357	A:A:W277	32.5201	26.45	No	Yes	0	7	6
59	A:A:V287	A:A:W277	12.1624	3.68	No	Yes	0	6	6
60	A:A:F273	A:A:V287	11.8612	5.24	Yes	No	0	9	6
61	A:A:S349	A:A:W277	14.9033	3.71	No	Yes	0	7	6
62	A:A:L346	A:A:S349	14.2976	4.5	No	No	0	4	7
63	A:A:L346	A:A:R342	13.9959	7.29	No	Yes	0	4	4
64	A:A:W281	B:B:D290	15.6191	6.7	Yes	Yes	1	5	6
65	B:B:L286	B:B:S277	71.1059	3	No	Yes	0	7	5
66	B:B:L318	B:B:S277	70.7575	3	No	Yes	0	6	5
67	B:B:L318	B:B:S275	70.6419	6.01	No	No	0	6	8
68	B:B:S275	B:B:T274	70.5282	3.2	No	No	0	8	8
69	B:B:D290	B:B:T274	15.7971	5.78	Yes	No	1	6	8
70	A:A:Y391	R:R:Y250	46.657	4.96	Yes	Yes	0	4	8
71	B:B:D228	B:B:S227	29.5299	4.42	Yes	No	0	9	6
72	B:B:D247	B:B:S227	29.0329	2.94	Yes	No	0	9	6
73	B:B:D247	B:B:H225	19.7109	8.82	Yes	Yes	2	9	9
74	B:B:H225	B:B:T243	10.8987	8.21	Yes	Yes	2	9	8
75	B:B:F222	B:B:F253	20.7778	6.43	Yes	Yes	2	8	6
76	B:B:D258	B:B:F222	19.7706	4.78	Yes	Yes	2	7	8
77	B:B:D258	B:B:R22	17.1774	10.72	Yes	No	0	7	6
78	B:B:I18	B:B:R22	14.5806	5.01	No	No	0	7	6
79	B:B:I18	G:G:A23	14.061	3.25	No	Yes	0	7	8
80	B:B:L14	G:G:A23	12.5017	1.58	No	Yes	0	8	8
81	B:B:L14	G:G:K20	10.9416	5.64	No	No	0	8	6
82	B:B:E10	G:G:K20	10.4214	4.05	No	No	0	8	6
83	B:B:F253	B:B:R251	14.8859	3.21	Yes	Yes	2	6	8
84	B:B:H62	B:B:Y105	16.5242	4.36	No	Yes	0	6	6
85	B:B:H62	B:B:R150	16.3356	16.93	No	No	0	6	6
86	B:B:C148	B:B:R150	16.1474	4.18	No	No	0	6	6
87	R:R:E412	R:R:F169	22.3807	8.16	Yes	Yes	35	8	7
88	R:R:F169	R:R:F413	22.125	7.5	Yes	No	0	7	5
89	R:R:F413	R:R:I165	22.0165	7.54	No	No	0	5	8
90	R:R:C403	R:R:I165	21.255	3.27	No	No	0	9	8
91	R:R:A162	R:R:C403	10.1974	3.61	No	No	0	9	9
92	R:R:A162	R:R:F184	10.0857	4.16	No	Yes	0	9	8
93	R:R:F184	R:R:L159	19.3923	4.87	Yes	Yes	0	8	9
94	R:R:F187	R:R:L159	16.8905	3.65	Yes	Yes	34	8	9
95	R:R:F187	R:R:N240	15.8643	16.92	Yes	No	0	8	9
96	R:R:N240	R:R:R190	14.2356	9.64	No	Yes	0	9	8
97	R:R:R190	R:R:Y152	11.9966	4.12	Yes	Yes	0	8	7
98	R:R:C403	R:R:L166	10.9671	4.76	No	Yes	0	9	8
99	R:R:F184	R:R:L166	10.1072	4.87	Yes	Yes	0	8	8
100	R:R:Y250	R:R:Y269	45.5245	9.93	Yes	Yes	0	8	7
101	R:R:V246	R:R:Y269	44.6969	3.79	No	Yes	0	8	7
102	R:R:I272	R:R:V246	44.042	3.07	Yes	No	0	6	8
103	R:R:I272	R:R:V276	43.6134	3.07	Yes	No	0	6	3
104	R:R:V276	R:R:Y242	44.0869	7.57	No	No	0	3	6
105	R:R:F280	R:R:Y242	43.794	7.22	Yes	No	0	5	6
106	R:R:F280	R:R:V281	43.3539	2.62	Yes	No	0	5	6
107	R:R:L231	R:R:V281	43.2071	2.98	No	No	0	5	6
108	R:R:G285	R:R:L231	43.0602	3.42	No	No	0	5	5
109	R:R:G285	R:R:W297	42.9131	2.81	No	Yes	0	5	8
110	R:R:D222	R:R:W297	37.4966	6.7	Yes	Yes	16	6	8
111	R:R:C296	R:R:D222	37.2649	3.11	Yes	Yes	0	9	6
112	R:R:C296	R:R:T298	36.8138	3.38	Yes	No	0	9	5
113	R:R:T298	R:R:W33	35.8628	12.13	No	Yes	20	5	3
114	R:R:W33	R:R:Y220	35.2774	12.54	Yes	No	0	3	3
115	R:R:V36	R:R:Y220	34.5204	12.62	No	No	0	2	3
116	R:R:L32	R:R:V36	34.3688	2.98	No	No	0	4	2
117	L:L:S17	R:R:L32	31.625	7.51	No	No	0	0	4
118	L:L:S17	R:R:T35	31.4718	6.4	No	No	0	0	5
119	R:R:P90	R:R:T35	31.3185	8.74	No	No	0	4	5
120	L:L:E21	R:R:P90	31.1651	7.86	Yes	No	0	0	4
121	L:L:E21	R:R:L89	29.5732	13.25	Yes	No	4	0	5
122	R:R:L89	R:R:Y88	29.4417	10.55	No	Yes	4	5	5
123	R:R:Y42	R:R:Y88	17.2448	13.9	Yes	Yes	4	6	5
124	R:R:C71	R:R:R43	14.025	5.57	No	Yes	4	9	4
125	R:R:C71	R:R:L50	20.5422	3.17	No	No	0	9	4
126	R:R:L50	R:R:R64	20.0548	9.72	No	No	0	4	4
127	R:R:D53	R:R:R64	19.0798	3.57	No	No	0	3	4
128	R:R:D53	R:R:P54	18.5921	4.83	No	No	0	3	2
129	R:R:P54	R:R:P55	18.1044	1.95	No	No	0	2	1
130	R:R:P55	R:R:P56	17.6166	1.95	No	No	0	1	1
131	R:R:D74	R:R:P56	14.6852	4.83	Yes	No	0	3	1
132	R:R:C62	R:R:D74	12.735	1.56	No	Yes	0	9	3
133	R:R:C62	R:R:W110	11.7574	6.53	No	No	0	9	9
134	B:B:R314	B:B:T274	54.6414	6.47	Yes	No	1	8	8
135	A:A:W281	B:B:R314	15.5375	22.99	Yes	Yes	1	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E9	R:R:Y148	3.37	0	No	Yes	0	7	0	1
L:L:T11	R:R:L141	16.21	0	Yes	No	0	5	0	1
L:L:T11	R:R:Y145	3.75	0	Yes	Yes	0	5	0	1
L:L:F12	R:R:Y145	7.22	32	Yes	Yes	0	5	0	1
L:L:F12	R:R:D198	5.97	32	Yes	No	0	7	0	1
L:L:F12	R:R:L201	3.65	32	Yes	No	0	7	0	1
L:L:F12	R:R:K202	9.93	32	Yes	No	0	4	0	1
L:L:T13	R:R:S31	9.59	0	No	No	0	4	0	1
L:L:S17	R:R:L32	7.51	0	No	No	0	4	0	1
L:L:S17	R:R:T35	6.4	0	No	No	0	5	0	1
L:L:Y19	R:R:Y205	5.96	0	No	No	0	3	0	1
L:L:L20	R:R:L32	4.15	0	No	No	0	4	0	1
L:L:E21	R:R:L89	13.25	4	Yes	No	0	5	0	1
L:L:E21	R:R:P90	7.86	4	Yes	No	0	4	0	1
L:L:E21	R:R:W91	5.45	4	Yes	Yes	0	4	0	1
L:L:Q23	R:R:Q211	6.4	33	No	No	0	4	0	1
L:L:Q23	R:R:W214	8.76	33	No	No	0	1	0	1
L:L:E27	R:R:Q211	19.11	33	No	No	0	4	0	1
L:L:F28	R:R:E68	7	0	No	No	0	4	0	1
L:L:F28	R:R:W214	5.01	0	No	No	0	1	0	1
L:L:I29	R:R:L118	5.71	0	No	No	0	4	0	1
R:R:S31	R:R:W33	4.94	20	No	Yes	4	3	1	2
R:R:E34	R:R:S31	5.75	20	Yes	No	4	4	2	1
R:R:E34	R:R:W33	3.27	20	Yes	Yes	4	3	2	2
R:R:P90	R:R:T35	8.74	0	No	No	4	5	1	1
R:R:P86	R:R:Y69	13.91	4	Yes	Yes	8	6	2	1
R:R:Y69	R:R:Y88	3.97	4	Yes	Yes	6	5	1	2
R:R:E127	R:R:Y69	3.37	0	No	Yes	2	6	2	1
R:R:P86	R:R:Y88	6.95	4	Yes	Yes	8	5	2	2
R:R:L89	R:R:Y88	10.55	4	No	Yes	5	5	1	2
R:R:L89	R:R:W91	7.97	4	No	Yes	5	4	1	1
R:R:E127	R:R:W91	3.27	0	No	Yes	2	4	2	1
R:R:K130	R:R:W91	4.64	0	No	Yes	1	4	2	1
R:R:L118	R:R:P119	8.21	0	No	No	4	6	1	2
R:R:I146	R:R:Y145	3.63	0	No	Yes	4	5	2	1
R:R:T149	R:R:Y145	8.74	0	No	Yes	7	5	2	1
R:R:D198	R:R:Y145	4.6	32	No	Yes	7	5	1	1
R:R:Y148	R:R:Y152	15.89	19	Yes	Yes	7	7	1	2
R:R:V194	R:R:Y148	3.79	19	No	Yes	7	7	2	1
R:R:L388	R:R:Y148	7.03	0	No	Yes	7	7	2	1
R:R:S392	R:R:Y148	6.36	19	No	Yes	9	7	2	1
R:R:V194	R:R:Y152	5.05	19	No	Yes	7	7	2	2
R:R:S392	R:R:Y152	8.9	19	No	Yes	9	7	2	2
R:R:K202	R:R:Y205	7.17	0	No	No	4	3	1	1
R:R:L32	R:R:V36	2.98	0	No	No	4	2	1	2
R:R:K113	R:R:L118	2.82	0	No	No	4	4	2	1
L:L:E9	R:R:K197	2.7	0	No	No	0	6	0	1
L:L:A25	R:R:Y69	2.67	0	No	Yes	0	6	0	1
R:R:E68	R:R:F66	2.33	0	No	No	4	7	1	2
L:L:L20	R:R:A208	1.58	0	No	No	0	4	0	1
L:L:A24	R:R:E68	1.51	0	No	No	0	4	0	1
L:L:T11	R:R:L142	1.47	0	Yes	No	0	3	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
56.25	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
55.56	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
52.63	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
50.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
46.15	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
41.67	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
40.91	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
40.00	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
40.00	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
37.04	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
33.33	Single	8HS2	Fab046	8HS2-GPR20-Fab046
33.33	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
32.00	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
31.03	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
31.03	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
30.77	Single	9IVM	LSN3318839	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
30.77	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
30.77	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
30.43	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
30.00	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
30.00	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
30.00	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
29.63	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
29.63	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
29.63	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
29.41	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
29.41	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
29.17	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
29.17	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
29.17	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
29.17	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
28.57	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
28.57	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
28.00	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
28.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
28.00	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
26.92	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
26.92	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
26.92	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
26.67	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
26.09	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
25.93	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
25.93	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
25.93	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
25.93	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
25.93	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
25.81	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
25.81	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
25.00	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
25.00	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
25.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
25.00	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
24.14	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
24.14	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
24.14	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
24.00	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
24.00	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
24.00	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
23.81	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
23.53	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
23.53	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
23.08	Single	6VCB	LSN3160440	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
23.08	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
23.08	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
23.08	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
22.73	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
22.58	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
22.22	Single	6FJ3	PTH	6FJ3-PTH1-PTH
22.22	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
22.22	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
22.22	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
22.22	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
22.22	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
22.22	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
22.22	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
22.22	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
22.22	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
22.22	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
22.22	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
22.22	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
22.22	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
22.22	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
22.22	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
22.22	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
21.88	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
21.88	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
21.88	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
21.74	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
21.43	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
21.43	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
21.43	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
21.43	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
21.43	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
21.43	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
21.43	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
21.43	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
21.21	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
21.05	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
21.05	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
21.05	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
21.05	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
20.83	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
20.83	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
20.83	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
20.83	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
20.69	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
20.69	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
20.69	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
20.69	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
20.69	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
20.69	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
20.69	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
20.59	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
20.00	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
20.00	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
20.00	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
20.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
20.00	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
20.00	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
20.00	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
20.00	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
19.35	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
19.35	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
19.35	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
19.35	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
19.23	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
19.23	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
19.23	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
19.05	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
19.05	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
19.05	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
19.05	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
19.05	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
18.75	Single	6LI0	C17	6LI0-GPR52-C17
18.75	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
18.75	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
18.75	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
18.75	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
18.75	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
18.75	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
18.75	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
18.52	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
18.52	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
18.52	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
18.52	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
18.52	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
18.52	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
18.52	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
18.52	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
18.52	Consensus	pac_on	Orthosteric Ligand	pac1_on
18.52	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
18.18	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
18.18	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
18.18	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
18.18	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
18.18	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
17.86	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
17.86	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
17.86	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
17.86	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
17.86	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
17.86	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
17.86	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
17.65	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
17.65	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
17.65	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
17.65	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
17.65	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
17.65	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
17.65	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
17.65	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
17.65	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
17.65	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
17.65	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
17.65	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
17.65	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
17.65	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
17.65	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
17.65	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
17.39	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
17.39	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
17.39	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
17.39	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
17.39	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
17.39	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
17.39	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
17.24	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
17.24	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
17.24	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
17.24	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
17.24	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
17.14	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
17.14	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.67	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
16.67	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
16.67	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
16.67	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
16.67	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
16.67	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
16.67	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
16.67	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
16.67	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
16.67	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
16.67	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
16.67	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
16.67	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
16.67	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
16.67	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
16.67	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
16.67	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
16.67	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
16.67	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
16.67	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
16.67	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
16.67	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
16.67	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
16.67	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
16.22	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
16.13	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
16.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
16.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
16.00	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
16.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
16.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
16.00	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
16.00	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
15.79	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
15.79	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
15.79	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
15.79	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
15.79	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
15.79	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
15.79	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
15.79	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
15.79	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
15.79	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
15.79	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
15.79	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
15.79	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
15.79	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
15.79	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
15.79	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
15.79	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
15.79	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
15.79	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
15.79	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
15.79	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
15.79	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
15.79	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
15.79	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
15.79	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
15.79	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
15.62	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
15.62	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
15.62	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
15.38	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
15.38	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
15.38	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
15.38	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
15.38	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
15.38	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
15.15	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
15.15	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
15.00	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
15.00	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
15.00	Single	7C4S	S1P	7C4S-S1P₃-S1P
15.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
15.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
15.00	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
15.00	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
15.00	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
15.00	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
15.00	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
15.00	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
15.00	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
15.00	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
15.00	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
15.00	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
15.00	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
15.00	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
15.00	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
15.00	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
15.00	Consensus	ep_off	Orthosteric Ligand	ep4_off
15.00	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
14.81	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
14.81	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
14.81	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
14.81	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
14.81	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
14.81	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
14.81	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
14.81	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
14.81	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
14.81	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
14.81	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
14.81	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
14.81	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
14.71	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
14.63	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
14.29	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
14.29	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
14.29	Single	6OS1	TRV026	6OS1-AT₁-TRV026
14.29	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
14.29	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
14.29	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
14.29	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
14.29	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
14.29	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
14.29	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
14.29	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
14.29	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
14.29	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
14.29	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
14.29	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
14.29	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
14.29	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
14.29	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
14.29	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
14.29	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
14.29	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
14.29	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
14.29	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
14.29	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
14.29	Single	9EGO	YVF	9EGO-CB₁-YVF-Gi1/β1/γ2
14.29	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
14.29	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
14.29	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
13.79	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
13.79	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
13.79	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
13.64	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
13.64	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
13.64	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
13.64	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
13.64	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
13.64	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
13.64	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
13.64	Single	6OS2	TRV026	6OS2-AT₁-TRV026
13.64	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
13.64	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
13.64	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
13.64	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
13.64	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.64	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
13.64	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
13.64	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
13.64	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
13.64	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
13.64	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
13.64	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
13.64	Single	9DGI	Z8526711350	9DGI-CB₁-Z8526711350
13.64	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.64	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
13.64	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
13.64	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
13.64	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
13.64	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
13.64	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
13.64	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
13.64	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
13.64	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
13.64	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
13.64	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
13.33	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
13.33	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
13.33	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
13.33	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
13.33	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
13.33	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
13.33	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
13.04	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
13.04	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
13.04	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
13.04	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
13.04	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
13.04	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
13.04	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
13.04	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
13.04	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
13.04	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
13.04	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
13.04	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
13.04	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
13.04	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
13.04	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.04	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
13.04	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.04	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.04	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
13.04	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
13.04	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
13.04	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
12.90	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.90	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
12.90	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
12.90	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
12.90	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
12.50	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
12.50	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
12.50	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
12.50	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
12.50	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
12.50	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
12.50	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
12.50	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
12.50	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
12.50	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
12.50	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
12.50	Single	9IZA	SCH900271	9IZA-HCA₂-SCH900271-Gi1/β1/γ2
12.50	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
12.50	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
12.50	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
12.50	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
12.12	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
12.12	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
12.00	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
12.00	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
12.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
12.00	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
12.00	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
12.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
12.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
12.00	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
12.00	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
12.00	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
12.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
12.00	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
12.00	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
11.76	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
11.76	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
11.76	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
11.76	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
11.76	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
11.76	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
11.76	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
11.76	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
11.76	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
11.54	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
11.54	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
11.54	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
11.54	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
11.54	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
11.54	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
11.54	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
11.54	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
11.54	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
11.54	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
11.54	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
11.43	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
11.43	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
11.11	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
11.11	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	6AKX	A4R	6AKX-CCR5-A4R
11.11	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
11.11	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
11.11	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
11.11	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
11.11	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
11.11	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
11.11	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
11.11	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
11.11	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
11.11	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
11.11	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
11.11	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
11.11	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
11.11	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
11.11	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
11.11	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Single	9K6L	SA0	9K6L-TAS2R16-SA0-Gi2/β1/γ2
11.11	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
11.11	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
11.11	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
11.11	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
11.11	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
11.11	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
11.11	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
11.11	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
11.11	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
10.71	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
10.71	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
10.71	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
10.71	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
10.71	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
10.71	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
10.71	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
10.71	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
10.71	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
10.53	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
10.53	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
10.53	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
10.53	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.53	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
10.53	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.53	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
10.53	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
10.53	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
10.53	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
10.53	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
10.53	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
10.53	Single	8YRG	Fospropofol	8YRG-MRGPRX4-Fospropofol-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
10.53	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
10.53	Single	9JMD	Azithromycin	9JMD-Motilin-Azithromycin-chim(Gs-CtGq)/β1/γ2
10.53	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
10.53	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
10.53	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
10.53	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
10.53	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
10.53	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
10.53	Consensus	hca_on	Orthosteric Ligand	hca2_on
10.53	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.34	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
10.34	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
10.34	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
10.34	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
10.34	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
10.34	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
10.34	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
10.34	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
10.34	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
10.34	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
10.34	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
10.34	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
10.00	Single	6IIV	Daltroban	6IIV-TXA2-Daltroban
10.00	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
10.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
10.00	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
10.00	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
10.00	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
10.00	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
10.00	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
10.00	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
10.00	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
10.00	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
10.00	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
10.00	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
10.00	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
10.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
10.00	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
10.00	Single	8ZYY	Neurotensin peptide 8-13	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
10.00	Single	9KFJ	PubChem 138319674	9KFJ-RXFP3-PubChem 138319674-Gi2/β1/γ2
10.00	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
10.00	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Consensus	blt_on	Orthosteric Ligand	blt1_on
10.00	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
10.00	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
10.00	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
10.00	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
10.00	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
10.00	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
10.00	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
10.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
10.00	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
10.00	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
10.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
9.68	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.68	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
9.68	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
9.68	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
9.68	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
9.68	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.68	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.68	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
9.52	Single	5C1M	BU72	5C1M-μ-BU72
9.52	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
9.52	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
9.52	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
9.52	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.52	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
9.52	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
9.52	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
9.52	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
9.52	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
9.52	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
9.52	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
9.52	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
9.52	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
9.52	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
9.52	Consensus	blt_off	Orthosteric Ligand	blt1_off
9.52	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
9.52	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
9.52	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.52	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.52	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
9.52	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
9.52	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
9.38	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
9.38	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
9.38	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
9.38	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
9.38	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
9.38	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
9.38	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
9.38	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
9.38	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
9.09	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
9.09	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
9.09	Single	5XR8	AM841	5XR8-CB₁-AM841
9.09	Single	5XRA	AM11542	5XRA-CB₁-AM11542
9.09	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
9.09	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
9.09	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
9.09	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
9.09	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
9.09	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
9.09	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
9.09	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042
9.09	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
9.09	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
9.09	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
9.09	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
9.09	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626
9.09	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
9.09	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
9.09	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
9.09	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
9.09	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
9.09	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
9.09	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
9.09	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
9.09	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
9.09	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
9.09	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
9.09	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
9.09	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
9.09	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
9.09	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
9.09	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
9.09	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
9.09	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
9.09	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
9.09	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
9.09	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
9.09	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
9.09	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
9.09	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
9.09	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
9.09	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
9.09	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
9.09	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
9.09	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
9.09	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
9.09	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
9.09	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
9.09	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
9.09	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
9.09	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
9.09	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
9.09	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
9.09	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
9.09	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
9.09	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
9.09	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
9.09	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
9.09	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
9.09	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
9.09	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
9.09	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
9.09	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
9.09	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
9.09	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
9.09	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
9.09	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
9.09	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
9.09	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
9.09	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
9.09	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
9.09	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
9.09	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
9.09	Single	7XW7	K1-70	7XW7-TSH-K1-70
9.09	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
9.09	Single	8E0G	BU72	8E0G-μ-BU72
9.09	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
9.09	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
9.09	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
9.09	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
9.09	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
9.09	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
9.09	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
9.09	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
9.09	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
9.09	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
9.09	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
9.09	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
9.09	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
9.09	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
9.09	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
9.09	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
9.09	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
9.09	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
9.09	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
9.09	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
9.09	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
9.09	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
9.09	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
9.09	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
9.09	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
9.09	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
9.09	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
9.09	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
9.09	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
9.09	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
9.09	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
9.09	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
9.09	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
9.09	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
9.09	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
9.09	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
9.09	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
9.09	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
9.09	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
9.09	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
9.09	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
9.09	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
9.09	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
9.09	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
9.09	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
9.09	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
9.09	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
9.09	Single	8WG9	(2S)-2-amino-4-phosphonobutanoic acid	8WG9-mGlu4; mGlu2-(2S)-2-amino-4-phosphonobutanoic acid
9.09	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
9.09	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
9.09	Single	8WGC	LY379268	8WGC-mGlu4; mGlu2-LY379268
9.09	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
9.09	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
9.09	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
9.09	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
9.09	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	8WVX	Norrin	8WVX-LGR4-Norrin
9.09	Single	8WVY	Norrin	8WVY-LGR4-Norrin
9.09	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
9.09	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
9.09	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
9.09	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
9.09	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
9.09	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
9.09	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
9.09	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
9.09	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
9.09	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
9.09	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
9.09	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
9.09	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
9.09	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
9.09	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
9.09	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
9.09	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
9.09	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
9.09	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
9.09	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
9.09	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
9.09	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
9.09	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
9.09	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
9.09	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
9.09	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
9.09	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
9.09	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
9.09	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
9.09	Single	9KHH	Norrin	9KHH-LGR4-Norrin
9.09	Single	9S37	NB21	9S37-LGR4-NB21
9.09	Single	9UTB	Sucralose	9UTB-TAS1R2; TAS1R3-Sucralose
9.09	Single	9UY3	Anamorelin	9UY3-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
9.09	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
9.09	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
9.09	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
9.09	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
9.09	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
9.09	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
9.09	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.09	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
9.09	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
9.09	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
9.09	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
9.09	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
9.09	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
9.09	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
9.09	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
9.09	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
9.09	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
9.09	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
8.82	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
8.82	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
8.70	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
8.70	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
8.70	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
8.70	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
8.70	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
8.70	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
8.70	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
8.70	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
8.70	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
8.70	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
8.70	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
8.70	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
8.70	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
8.70	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
8.70	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
8.70	Single	8XQJ	JN241	8XQJ-Apelin-JN241
8.70	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
8.70	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
8.70	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
8.70	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
8.70	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
8.70	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
8.70	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
8.70	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
8.70	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
8.70	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
8.70	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
8.70	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
8.70	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
8.70	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
8.70	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
8.70	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
8.70	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
8.57	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
8.57	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
8.33	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
8.33	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
8.33	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
8.33	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
8.33	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
8.33	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
8.33	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
8.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
8.33	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
8.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
8.33	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
8.33	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
8.33	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
8.33	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
8.33	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
8.33	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
8.33	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
8.33	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
8.33	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
8.33	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
8.33	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
8.33	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
8.33	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
8.33	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
8.33	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
8.33	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
8.33	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
8.33	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
8.00	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
8.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
8.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.00	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
8.00	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
8.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
8.00	Single	8XQJ	JN241	8XQJ-Apelin-JN241
8.00	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
8.00	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
8.00	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
8.00	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
8.00	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
8.00	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
8.00	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
8.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
8.00	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
8.00	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
7.69	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
7.69	Single	7QA8	Peptide	7QA8-STE2-Peptide
7.69	Single	7QA8	Peptide	7QA8-STE2-Peptide
7.69	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
7.69	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
7.69	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
7.69	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
7.69	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
7.69	Single	8WKY	PG-934	8WKY-MC₄-PG-934
7.69	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
7.69	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
7.69	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
7.69	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
7.69	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
7.69	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
7.69	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
7.69	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
7.41	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
7.41	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
7.41	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
7.41	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
7.41	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
7.41	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
7.41	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
7.41	Single	9E82	SDF-1-beta	9E82-ACKR3-SDF-1-β-Arrestin2
7.41	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
7.41	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
7.41	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
7.41	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
7.41	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
7.41	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
7.41	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
7.41	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
7.41	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
7.41	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
7.14	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
7.14	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
7.14	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
7.14	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
7.14	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
7.14	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
7.14	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
7.14	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
7.14	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
7.14	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
7.14	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
7.14	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
7.14	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
6.90	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
6.90	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
6.90	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
6.90	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
6.90	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
6.90	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
6.90	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.90	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
6.90	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
6.90	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
6.90	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
6.90	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
6.90	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
6.90	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
6.90	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
6.90	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
6.67	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
6.67	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
6.67	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
6.67	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
6.67	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
6.67	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
6.67	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
6.67	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
6.67	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
6.67	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
6.67	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
6.67	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
6.67	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
6.67	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
6.67	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
6.67	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
6.67	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
6.67	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
6.45	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
6.45	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
6.45	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
6.45	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
6.45	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
6.45	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
6.45	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
6.45	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
6.45	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
6.45	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
6.45	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
6.25	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
6.25	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
6.25	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
6.25	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.25	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
6.25	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
6.25	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
6.25	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
6.25	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
6.06	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
6.06	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.06	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
6.06	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
5.88	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
5.88	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
5.88	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.88	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
5.88	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
5.88	Single	9JHJ	C18:0 Ceramide	9JHJ-FPR2-ALX-C18:0 Ceramide-Gi1/β1/γ2
5.88	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
5.88	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
5.71	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
5.71	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
5.56	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
5.56	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
5.56	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.56	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
5.56	Single	7XP6	Strychnine	7XP6-TAS2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
5.56	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
5.56	Single	8YKD	Dehydroepiandrosterone	8YKD-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
5.56	Single	8ZYU	Neurotensin peptide 8-13	8ZYU-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
5.56	Single	9B9Y	7DY	9B9Y-CB₁-7DY
5.56	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
5.56	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
5.56	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
5.56	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
5.56	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.41	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
5.26	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
5.26	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
5.26	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
5.26	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
5.26	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
5.26	Single	5WS3	EMPA	5WS3-OX₂-EMPA
5.26	Single	6B73	MP1104	6B73-κ-MP1104
5.26	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
5.26	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
5.26	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
5.26	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
5.26	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
5.26	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
5.26	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
5.26	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
5.26	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
5.26	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
5.26	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
5.26	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
5.26	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
5.26	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
5.26	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
5.26	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
5.26	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
5.26	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
5.26	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
5.26	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
5.26	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
5.26	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
5.26	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
5.26	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
5.26	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
5.26	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
5.00	Single	3REY	XAC	3REY-A_2A-XAC
5.00	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
5.00	Single	6IQL	L745870	6IQL-D₄-L745870
5.00	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
5.00	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
5.00	Single	6TPG	EMPA	6TPG-OX₂-EMPA
5.00	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
5.00	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
5.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
5.00	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
5.00	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
5.00	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
5.00	Single	7F61	PF-03654746	7F61-H₃-PF-03654746
5.00	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.00	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
5.00	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
5.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
5.00	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
5.00	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
5.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
5.00	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
5.00	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
5.00	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
5.00	Single	8K9L	Damgo	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
5.00	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
5.00	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
5.00	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
5.00	Single	8Y6Y	GLPG0974	8Y6Y-FFA2-GLPG0974
5.00	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
5.00	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
5.00	Single	9KPD	SA0	9KPD-TAS2R16-SA0-chim(Gs-CtGt3)/β1/γ2
5.00	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
5.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
5.00	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
5.00	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
5.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
4.76	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
4.76	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
4.76	Single	5DHG	C-35	5DHG-NOP-C-35
4.76	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
4.76	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
4.76	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
4.76	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
4.76	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
4.76	Single	6D27	CAY10471	6D27-DP₂-CAY10471
4.76	Single	6GPS	MK0812	6GPS-CCR2-MK0812
4.76	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
4.76	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
4.76	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
4.76	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
4.76	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
4.76	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
4.76	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
4.76	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.76	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
4.76	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
4.76	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
4.76	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.76	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
4.76	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
4.76	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-Gi1/β1/γ1
4.76	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
4.76	Single	8T1W	CVN424	8T1W-GPR6-CVN424
4.76	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
4.76	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
4.76	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
4.76	Single	9IMA	Talquetamab	9IMA-GPRC5D-Talquetamab
4.76	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
4.76	Consensus	cck_off	Orthosteric Ligand	ccka_off
4.76	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
4.76	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
4.76	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.76	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
4.76	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
4.55	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
4.55	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
4.55	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
4.55	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
4.55	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
4.55	Single	5WQC	EMPA	5WQC-OX₂-EMPA
4.55	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
4.55	Single	6GPX	MK0812	6GPX-CCR2-MK0812
4.55	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
4.55	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.55	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
4.55	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
4.55	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
4.55	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
4.55	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
4.55	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
4.55	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
4.55	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
4.55	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
4.55	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
4.55	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
4.55	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
4.55	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
4.55	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
4.55	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
4.55	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
4.55	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
4.55	Single	8WGB	VU0155041	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
4.55	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.55	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
4.55	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
4.55	Single	9I52	A1IZU	9I52-D₁-A1IZU-Gs/β1/γ2
4.55	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
4.55	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
4.55	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.55	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.55	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
4.55	Consensus	dp_off	Orthosteric Ligand	dp2_off
4.35	Single	4DJH	JDTic	4DJH-κ-JDTic
4.35	Single	5V56	TC114	5V56-SMO-TC114
4.35	Single	5V57	TC114	5V57-SMO-TC114
4.35	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
4.35	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
4.35	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
4.35	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
4.35	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.35	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
4.35	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
4.35	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.35	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
4.35	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
4.35	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
4.35	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
4.35	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
4.35	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
4.35	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
4.35	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
4.35	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
4.35	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
4.35	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.35	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
4.35	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
4.35	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
4.35	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
4.35	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
4.35	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.35	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
4.35	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
4.35	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
4.35	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
4.35	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
4.35	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.35	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
4.35	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
4.35	Single	8ZWF	JR14a	8ZWF-C3a_B-JR14a
4.35	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
4.35	Single	9I54	A1IZV	9I54-D₁-A1IZV-Gs/β1/γ2
4.35	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
4.35	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
4.35	Consensus	a2_on	Orthosteric Ligand	a2b_on
4.35	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
4.35	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.35	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.35	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.35	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.35	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.35	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
4.35	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
4.35	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
4.17	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
4.17	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
4.17	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
4.17	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
4.17	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.17	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
4.17	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
4.17	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
4.17	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
4.17	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
4.17	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
4.17	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
4.17	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
4.17	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
4.17	Single	8JWY	2-118	8JWY-A_2A-2-118
4.17	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.17	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
4.17	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
4.17	Single	9GL2	Befiradol	9GL2-5-HT_1A-Befiradol-Gs/β1/γ2
4.17	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
4.17	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.17	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.17	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
4.17	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.17	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
4.17	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
4.17	Consensus	orexin_on	Orthosteric Ligand	ox2_on
4.00	Single	5X93	K-8794	5X93-ET_B-K-8794
4.00	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
4.00	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
4.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
4.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
4.00	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.00	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
4.00	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
4.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
4.00	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
4.00	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
4.00	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
4.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
4.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
4.00	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
4.00	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
4.00	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
4.00	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.00	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
4.00	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
4.00	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
4.00	Single	9DYE	Buspirone	9DYE-5-HT_1A-Buspirone-Go/β1/γ2
4.00	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
4.00	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
4.00	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
4.00	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
4.00	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.00	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.00	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
4.00	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
4.00	Consensus	endothelin_off	Orthosteric Ligand	etb_off
4.00	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
4.00	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.00	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
4.00	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
4.00	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
3.85	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
3.85	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
3.85	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
3.85	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
3.85	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
3.85	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
3.85	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	9MD1	Buspirone	9MD1-5-HT_1A-Buspirone-Gz/β1/γ2
3.85	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.85	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
3.85	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
3.85	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.85	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.70	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
3.70	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
3.70	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
3.70	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
3.70	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
3.70	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
3.70	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
3.70	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-Gi1/β1/γ1
3.70	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
3.70	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
3.70	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
3.70	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
3.70	Single	9M4T	Silodosin	9M4T-Alpha1A-Silodosin
3.70	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
3.70	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.70	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.70	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
3.70	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
3.70	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
3.57	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
3.57	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
3.57	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.57	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
3.57	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
3.57	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
3.57	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
3.57	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
3.57	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.57	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.57	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
3.45	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
3.45	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
3.45	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.45	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
3.45	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
3.45	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
3.45	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
3.45	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.45	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.45	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
3.45	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
3.45	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.45	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.45	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.45	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
3.45	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
3.45	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
3.45	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
3.45	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
3.33	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
3.33	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3
3.33	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
3.33	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
3.33	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.23	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.23	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.12	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
3.03	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
3.03	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
3.03	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3
2.94	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
2.94	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2

PDB Summary
PDB	9IVG
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	GLP-1
Species	Homo Sapiens
Ligand	GLP-1 (Truncated)
Other Ligand(s)	-
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	3
Date	2024-11-27
D.O.I.	doi.org/10.1016/j.apsb.2024.09.002

Net Summary
I_min	3.21
Number of Linked Nodes	980
Number of Links	1146
Number of Hubs	174
Number of Links mediated by Hubs	648
Number of Communities	36
Number of Nodes involved in Communities	232
Number of Links involved in Communities	309

Path Summary
Number Of Nodes in MetaPath	136
Number Of Links MetaPath	135
Number of Shortest Paths	3172977
Length Of Smallest Path	3
Average Path Length	43.5067
Length of Longest Path	89
Minimum Path Strength	1.22
Average Path Strength	6.9982
Maximum Path Strength	23.34
Minimum Path Correlation	0.7
Average Path Correlation	0.994247
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.96078
Average % Of Corr. Nodes	44.8018
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.5792
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • FnI-like domain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • FnI-like domain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>9IVG_Chain_A E K A E K I E K Q L Q K D K Q V Y R A T H R L L L L G A S G K S T I V K Q M R I H Q D L R R V T S G I F E T K F Q V D K V N F H M F D V G Q R D E R R K W I Q C F N D V T A I I F V V S S Y N R L Q E A L N F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C V D T E N R R F N D C R D I I Q R M H L R Q Y E L L T L S A D A V R S M D N Y Q V T K A D D D S A I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>9IVG_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>9IVG_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P43220
Sequence	>9IVG_Chain_R S L W E T V Q K W R E Y R R Q C Q R S L T E D P P P A T D L F C N R T F D E Y A C W P D G E P G S F V N V S C P W Y L P W A S S V P Q G H V Y R F C T A E G L W L Q K D N S S L P W R D L S E C E E S K S S P E E Q L L F L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L S C R L V F L L M Q Y C V A A N Y Y W L L V E G V Y L Y T L L A F S V L S E Q W I F R L Y V S I G W G V P L L F V V P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F V R V I C I V V S K L K A N L M C K T D I K C R L A K S T L T L I P L L G T H E V I F A H A R G T L R F I K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q L E F R K S W E R W R L E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	doi.org/10.1038/nature22378
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.2	2020-03-18	doi.org/10.1038/s41467-020-14934-5
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.1	2019-11-13	doi.org/10.1107/S2052252519013496
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	doi.org/10.1038/nature22378
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	doi.org/10.1021/acs.jmedchem.1c01856
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	doi.org/10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	doi.org/10.1038/nature22394
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	doi.org/10.1038/nature22800
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	doi.org/10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	doi.org/10.1038/nature25773
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	9EBN	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBN (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-	Gs/β1/γ2	3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-		3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	8YWF	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ2	2.74	2025-04-16	To be published
	8YWF (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.74	2025-04-16	To be published
	9BYO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-	Gs/β1/γ2	2.31	2025-06-11	To be published
	9BYO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-		2.31	2025-06-11	To be published
	9C0K	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	2.72	2025-06-11	To be published
	9C0K (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		2.72	2025-06-11	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9IVG.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.