psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:K71	7.88	Yes	Yes	1	0	5
2	L:L:?1	R:R:R75	7.64	Yes	Yes	1	0	4
3	L:L:?1	R:R:S156	6.29	Yes	No	0	0	9
4	L:L:?1	R:R:T179	8.24	Yes	Yes	1	0	7
5	L:L:?1	R:R:Y227	15.56	Yes	Yes	1	0	7
6	L:L:?1	R:R:D309	2.84	Yes	Yes	1	0	8
7	L:L:?1	R:R:K314	3.94	Yes	No	0	0	5
8	M:M:?1	S:S:K71	7.88	Yes	Yes	2	0	5
9	M:M:?1	S:S:R75	7.64	Yes	Yes	2	0	4
10	M:M:?1	S:S:S156	6.29	Yes	No	0	0	9
11	M:M:?1	S:S:T179	7.21	Yes	Yes	2	0	7
12	M:M:?1	S:S:Y227	15.56	Yes	Yes	2	0	7
13	M:M:?1	S:S:D309	2.84	Yes	Yes	2	0	8
14	M:M:?1	S:S:S310	4.2	Yes	Yes	2	0	6
15	M:M:?1	S:S:K314	3.94	Yes	No	0	0	5
16	R:R:H38	R:R:S39	4.18	No	No	0	4	5
17	R:R:L103	R:R:S39	4.5	Yes	No	0	5	5
18	R:R:I102	R:R:I40	4.42	Yes	No	0	8	4
19	R:R:I40	R:R:N356	4.25	No	Yes	0	4	8
20	R:R:I40	R:R:W358	5.87	No	No	0	4	4
21	R:R:R101	R:R:R41	13.86	No	No	0	5	3
22	R:R:V100	R:R:V42	3.21	Yes	No	0	7	5
23	R:R:R355	R:R:V42	2.62	Yes	No	0	4	5
24	R:R:G44	R:R:T97	3.64	No	No	0	9	7
25	R:R:D45	R:R:T97	5.78	No	No	0	8	7
26	R:R:I46	R:R:L98	2.85	No	Yes	0	5	9
27	R:R:I46	R:R:S148	4.64	No	No	0	5	4
28	R:R:I46	R:R:L416	4.28	No	No	0	5	8
29	R:R:D145	R:R:I47	4.2	No	No	0	4	5
30	R:R:I147	R:R:I47	2.94	No	No	0	5	5
31	R:R:L48	R:R:M412	4.24	No	Yes	0	7	7
32	R:R:G50	R:R:M79	3.49	No	Yes	0	8	8
33	R:R:L51	R:R:T105	4.42	No	No	0	7	7
34	R:R:F119	R:R:L51	6.09	No	No	0	5	7
35	R:R:L51	R:R:V162	4.47	No	Yes	0	7	5
36	R:R:F52	R:R:L76	3.65	Yes	No	1	9	4
37	R:R:F52	R:R:M79	6.22	Yes	Yes	1	9	8
38	R:R:F52	R:R:Y176	8.25	Yes	Yes	1	9	7
39	R:R:F52	R:R:V405	2.62	Yes	No	1	9	8
40	R:R:A154	R:R:P53	3.74	No	No	0	5	5
41	R:R:H55	R:R:V54	4.15	Yes	No	5	8	5
42	R:R:D104	R:R:V54	11.69	No	No	5	9	5
43	R:R:V54	R:R:W358	6.13	No	No	0	5	4
44	R:R:C64	R:R:H55	2.95	No	Yes	5	9	8
45	R:R:H55	R:R:L67	6.43	Yes	No	5	8	3
46	R:R:D104	R:R:H55	6.3	No	Yes	5	9	8
47	R:R:C106	R:R:H55	4.42	Yes	Yes	5	7	8
48	R:R:E361	R:R:H55	6.15	No	Yes	5	5	8
49	R:R:A56	R:R:E66	3.02	No	No	0	3	3
50	R:R:A56	R:R:K68	4.82	No	No	0	3	5
51	R:R:K57	R:R:R108	11.14	No	No	0	2	4
52	R:R:E59	R:R:E66	5.07	No	No	0	1	3
53	R:R:P63	R:R:V62	3.53	No	No	0	2	1
54	R:R:P63	R:R:Y111	2.78	No	Yes	0	2	3
55	R:R:C106	R:R:C64	7.28	Yes	No	5	7	9
56	R:R:C64	R:R:Y111	5.38	No	Yes	5	9	3
57	R:R:E361	R:R:L67	11.93	No	No	5	5	3
58	R:R:E365	R:R:L67	7.95	No	No	5	2	3
59	R:R:K68	R:R:K71	8.62	No	Yes	0	5	5
60	R:R:K68	R:R:S107	4.59	No	No	0	5	3
61	R:R:F362	R:R:K69	7.44	Yes	No	1	6	4
62	R:R:K69	R:R:N366	4.2	No	Yes	1	4	3
63	R:R:K71	R:R:R75	3.71	Yes	Yes	1	5	4
64	R:R:E284	R:R:K71	4.05	No	Yes	0	3	5
65	R:R:F362	R:R:I73	8.79	Yes	No	0	6	7
66	R:R:F345	R:R:H74	6.79	Yes	No	1	6	7
67	R:R:H74	R:R:Y396	5.44	No	Yes	1	7	5
68	R:R:R75	R:R:Y176	6.17	Yes	Yes	1	4	7
69	R:R:E399	R:R:R75	13.96	Yes	Yes	1	5	4
70	R:R:K401	R:R:R75	8.66	No	Yes	1	4	4
71	R:R:E77	R:R:L76	3.98	Yes	No	1	8	4
72	R:R:L76	R:R:N356	4.12	No	Yes	1	4	8
73	R:R:E77	R:R:Y344	6.73	Yes	Yes	0	8	7
74	R:R:E77	R:R:F345	5.83	Yes	Yes	1	8	6
75	R:R:E77	R:R:N353	6.57	Yes	Yes	1	8	3
76	R:R:E77	R:R:N356	7.89	Yes	Yes	1	8	8
77	R:R:A78	R:R:F341	4.16	No	Yes	22	8	8
78	R:R:A78	R:R:V402	5.09	No	No	22	8	6
79	R:R:M79	R:R:V100	3.04	Yes	Yes	1	8	7
80	R:R:I102	R:R:M79	4.37	Yes	Yes	1	8	8
81	R:R:I151	R:R:M79	4.37	No	Yes	0	7	8
82	R:R:I102	R:R:L80	2.85	Yes	No	0	8	5
83	R:R:L80	R:R:R355	14.58	No	Yes	0	5	4
84	R:R:Q85	R:R:Y81	16.91	No	Yes	0	8	7
85	R:R:G340	R:R:Y81	2.9	No	Yes	0	5	7
86	R:R:F341	R:R:Y81	4.13	Yes	Yes	0	8	7
87	R:R:Y344	R:R:Y81	7.94	Yes	Yes	0	7	7
88	R:R:A82	R:R:I406	3.25	No	No	0	8	8
89	R:R:A82	R:R:V409	5.09	No	No	0	8	8
90	R:R:I83	R:R:L98	2.85	No	Yes	0	7	9
91	R:R:I83	R:R:V100	6.14	No	Yes	0	7	7
92	R:R:I83	R:R:V409	3.07	No	No	0	7	8
93	R:R:D84	R:R:R355	9.53	No	Yes	0	7	4
94	R:R:K88	R:R:Q85	5.42	No	No	0	5	8
95	R:R:I86	R:R:L98	2.85	No	Yes	0	9	9
96	R:R:I86	R:R:Y410	9.67	No	No	0	9	7
97	R:R:A413	R:R:I86	4.87	No	No	0	9	9
98	R:R:D89	R:R:P90	6.44	No	No	0	6	4
99	R:R:D89	R:R:L92	6.79	No	No	0	6	6
100	R:R:D91	R:R:P90	3.22	No	No	0	3	4
101	R:R:L92	R:R:Y414	7.03	No	No	0	6	7
102	R:R:H417	R:R:L92	5.14	No	No	0	7	6
103	R:R:L93	R:R:L98	4.15	No	Yes	0	9	9
104	R:R:I428	R:R:N95	2.83	No	No	0	4	8
105	R:R:H420	R:R:I96	2.65	No	No	0	3	5
106	R:R:I102	R:R:V100	6.14	Yes	Yes	1	8	7
107	R:R:L103	R:R:R101	3.64	Yes	No	0	5	5
108	R:R:L103	R:R:Q115	11.98	Yes	No	5	5	6
109	R:R:L103	R:R:T118	2.95	Yes	No	5	5	2
110	R:R:F119	R:R:L103	6.09	No	Yes	0	5	5
111	R:R:C106	R:R:D104	4.67	Yes	No	5	7	9
112	R:R:A112	R:R:T105	3.36	No	No	0	7	7
113	R:R:C106	R:R:Y111	5.38	Yes	Yes	5	7	3
114	R:R:D109	R:R:T110	2.89	No	No	0	4	3
115	R:R:D109	R:R:M161	5.54	No	No	0	4	6
116	R:R:D109	S:S:R188	11.91	No	No	0	4	6
117	R:R:T110	S:S:R167	7.76	No	No	0	3	5
118	R:R:Q115	R:R:Y111	6.76	No	Yes	5	6	3
119	R:R:L113	R:R:M161	9.9	Yes	No	0	5	6
120	R:R:I165	R:R:L113	2.85	No	Yes	0	5	5
121	R:R:L113	S:S:I165	2.85	Yes	No	0	5	5
122	R:R:L113	S:S:L168	2.77	Yes	No	0	5	5
123	R:R:E114	S:S:L168	2.65	No	No	0	4	5
124	R:R:Q115	R:R:T118	2.83	No	No	5	6	2
125	R:R:S116	R:R:V162	4.85	No	Yes	1	5	5
126	R:R:I165	R:R:S116	6.19	No	No	0	5	5
127	R:R:L166	R:R:S116	3	Yes	No	1	6	5
128	R:R:F119	R:R:V150	3.93	No	No	0	5	6
129	R:R:F169	R:R:V120	14.42	Yes	No	0	6	4
130	R:R:K146	R:R:L123	2.82	No	No	0	3	3
131	R:R:F169	R:R:L123	7.31	Yes	No	0	6	3
132	R:R:I437	R:R:S148	3.1	No	No	0	3	4
133	R:R:G149	R:R:M412	3.49	No	Yes	0	8	7
134	R:R:L166	R:R:V150	4.47	Yes	No	0	6	6
135	R:R:I151	R:R:V409	3.07	No	No	0	7	8
136	R:R:G152	R:R:Q173	4.93	No	Yes	0	8	8
137	R:R:A153	R:R:V158	3.39	No	No	0	5	3
138	R:R:A153	R:R:S159	3.42	No	Yes	0	5	8
139	R:R:A154	R:R:Y176	2.67	No	Yes	0	5	7
140	R:R:A155	R:R:V158	3.39	No	No	0	4	3
141	R:R:A180	R:R:S156	3.42	No	No	0	7	9
142	R:R:N226	R:R:S157	5.96	No	No	0	6	5
143	R:R:Q173	R:R:S159	2.89	Yes	Yes	1	8	8
144	R:R:S159	R:R:S175	3.26	Yes	No	1	8	8
145	R:R:S159	R:R:S178	6.52	Yes	No	1	8	8
146	R:R:F192	R:R:S159	2.64	Yes	Yes	1	8	8
147	R:R:E182	R:R:I160	6.83	No	Yes	1	4	5
148	R:R:I160	R:R:L183	4.28	Yes	Yes	1	5	8
149	R:R:I160	R:R:Y189	6.04	Yes	Yes	1	5	6
150	R:R:I160	R:R:N226	4.25	Yes	No	0	5	6
151	R:R:M161	S:S:N164	2.8	No	No	0	6	5
152	R:R:L166	R:R:V162	2.98	Yes	Yes	1	6	5
153	R:R:Q173	R:R:V162	5.73	Yes	Yes	1	8	5
154	R:R:A163	R:R:Q173	4.55	No	Yes	0	7	8
155	R:R:N164	R:R:Y189	4.65	No	Yes	0	5	6
156	R:R:N164	S:S:M161	2.8	No	No	0	5	6
157	R:R:I171	R:R:L166	5.71	No	Yes	0	6	6
158	R:R:L166	R:R:Q173	5.32	Yes	Yes	1	6	8
159	R:R:D190	R:R:R167	13.1	No	No	0	6	5
160	R:R:R167	S:S:T110	7.76	No	No	0	5	3
161	R:R:L168	S:S:L113	2.77	No	No	0	5	5
162	R:R:L168	S:S:E114	2.65	No	No	0	5	4
163	R:R:F191	R:R:K170	6.2	No	No	0	7	4
164	R:R:I171	R:R:P172	3.39	No	Yes	0	6	9
165	R:R:F191	R:R:P172	2.89	No	Yes	0	7	9
166	R:R:L442	R:R:P172	6.57	Yes	Yes	0	6	9
167	R:R:I446	R:R:P172	3.39	Yes	Yes	0	6	9
168	R:R:F192	R:R:Q173	8.2	Yes	Yes	1	8	8
169	R:R:A408	R:R:I174	3.25	No	No	0	9	7
170	R:R:I174	R:R:M412	7.29	No	Yes	21	7	7
171	R:R:I174	R:R:I446	2.94	No	Yes	21	7	6
172	R:R:S175	R:R:S178	6.52	No	No	1	8	8
173	R:R:F192	R:R:S175	3.96	Yes	No	1	8	8
174	R:R:A177	R:R:Y176	2.67	No	Yes	0	6	7
175	R:R:V405	R:R:Y176	8.83	No	Yes	1	8	7
176	R:R:A177	R:R:K401	3.21	No	No	0	6	4
177	R:R:T179	R:R:V196	3.17	Yes	Yes	0	7	7
178	R:R:D199	R:R:T179	10.12	Yes	Yes	0	8	7
179	R:R:D309	R:R:T179	2.89	Yes	Yes	1	8	7
180	R:R:D199	R:R:P181	6.44	Yes	No	0	8	5
181	R:R:P181	R:R:S200	3.56	No	No	0	5	3
182	R:R:E182	R:R:Y189	11.22	No	Yes	1	4	6
183	R:R:L183	R:R:Y189	7.03	Yes	Yes	1	8	6
184	R:R:F192	R:R:L183	19.49	Yes	Yes	1	8	8
185	R:R:L183	R:R:R194	6.07	Yes	Yes	1	8	9
186	R:R:R194	R:R:S184	5.27	Yes	No	1	9	8
187	R:R:P198	R:R:S184	3.56	Yes	No	1	7	8
188	R:R:D466	R:R:S184	8.83	Yes	No	1	8	8
189	R:R:D185	R:R:T187	7.23	No	No	0	7	2
190	R:R:N186	R:R:N464	6.81	No	No	0	7	6
191	R:R:R188	R:R:Y189	8.23	No	Yes	0	6	6
192	R:R:R188	S:S:D109	11.91	No	No	0	6	4
193	R:R:F191	R:R:L443	8.53	No	No	0	7	5
194	R:R:F192	R:R:R194	4.28	Yes	Yes	1	8	9
195	R:R:R447	R:R:S193	6.59	No	No	16	5	7
196	R:R:F461	R:R:S193	2.64	Yes	No	16	8	7
197	R:R:G465	R:R:S193	3.71	No	No	16	7	7
198	R:R:R194	R:R:V196	2.62	Yes	Yes	0	9	7
199	R:R:P198	R:R:R194	7.21	Yes	Yes	1	7	9
200	R:R:D466	R:R:R194	11.91	Yes	Yes	1	8	9
201	R:R:F404	R:R:V195	2.62	Yes	No	0	7	9
202	R:R:F461	R:R:V195	2.62	Yes	No	0	8	9
203	R:R:P197	R:R:V196	3.53	No	Yes	0	8	7
204	R:R:F404	R:R:V196	7.87	Yes	Yes	0	7	7
205	R:R:G469	R:R:P197	4.06	No	No	0	5	8
206	R:R:P197	R:R:Y471	8.34	No	Yes	0	8	8
207	R:R:P198	R:R:Y201	5.56	Yes	Yes	1	7	4
208	R:R:D466	R:R:P198	9.66	Yes	Yes	1	8	7
209	R:R:D199	R:R:Q202	5.22	Yes	Yes	0	8	9
210	R:R:D199	R:R:Y227	4.6	Yes	Yes	0	8	7
211	R:R:G469	R:R:Y201	4.35	No	Yes	0	5	4
212	R:R:Y201	R:R:Y471	2.98	Yes	Yes	1	4	8
213	R:R:W491	R:R:Y201	3.86	Yes	Yes	1	6	4
214	R:R:M206	R:R:Q202	2.72	No	Yes	1	7	9
215	R:R:F281	R:R:Q202	3.51	Yes	Yes	1	7	9
216	R:R:Q202	R:R:S308	4.33	Yes	Yes	1	9	8
217	R:R:D309	R:R:Q202	6.53	Yes	Yes	1	8	9
218	R:R:I331	R:R:Q202	2.74	Yes	Yes	1	6	9
219	R:R:Q204	R:R:V207	2.87	Yes	No	1	3	6
220	R:R:D208	R:R:Q204	7.83	No	Yes	1	5	3
221	R:R:I238	R:R:Q204	4.12	Yes	Yes	1	5	3
222	R:R:Q204	R:R:W491	3.29	Yes	Yes	1	3	6
223	R:R:A205	R:R:W491	9.08	No	Yes	0	8	6
224	R:R:F281	R:R:M206	6.22	Yes	No	1	7	7
225	R:R:I331	R:R:M206	2.92	Yes	No	1	6	7
226	R:R:F235	R:R:V207	5.24	No	No	0	5	6
227	R:R:I238	R:R:V207	6.14	Yes	No	1	5	6
228	R:R:D208	R:R:W491	6.7	No	Yes	1	5	6
229	R:R:D208	R:R:L495	2.71	No	Yes	1	5	7
230	R:R:I209	R:R:I331	2.94	No	Yes	0	8	6
231	R:R:I209	R:R:I473	5.89	No	No	0	8	8
232	R:R:I209	R:R:L495	2.85	No	Yes	0	8	7
233	R:R:V210	R:R:V245	3.21	No	No	0	7	7
234	R:R:L213	R:R:W215	7.97	Yes	Yes	1	7	9
235	R:R:L213	R:R:V499	2.98	Yes	No	0	7	4
236	R:R:L213	R:R:M502	4.24	Yes	Yes	1	7	7
237	R:R:H511	R:R:L213	7.71	Yes	Yes	1	4	7
238	R:R:A277	R:R:W215	3.89	No	Yes	1	8	9
239	R:R:L304	R:R:W215	4.56	No	Yes	1	7	9
240	R:R:I306	R:R:W215	3.52	No	Yes	0	7	9
241	R:R:W215	R:R:W504	4.69	Yes	Yes	1	9	7
242	R:R:H511	R:R:W215	4.23	Yes	Yes	1	4	9
243	R:R:S514	R:R:W215	4.94	No	Yes	1	9	9
244	R:R:N216	R:R:V515	5.91	No	No	0	7	5
245	R:R:A248	R:R:Y217	5.34	No	Yes	0	8	9
246	R:R:T272	R:R:Y217	4.99	Yes	Yes	12	3	9
247	R:R:A275	R:R:Y217	2.67	No	Yes	12	7	9
248	R:R:C516	R:R:Y217	16.13	No	Yes	12	9	9
249	R:R:C535	R:R:Y217	5.38	Yes	Yes	12	9	9
250	R:R:F235	R:R:V218	2.62	No	No	0	5	8
251	R:R:A277	R:R:V218	3.39	No	No	0	8	8
252	R:R:Q249	R:R:S219	2.89	No	No	0	6	8
253	R:R:T220	R:R:V232	4.76	No	No	0	5	5
254	R:R:I247	R:R:T220	3.04	No	No	0	6	5
255	R:R:S250	R:R:T220	3.2	No	No	0	5	5
256	R:R:L221	R:R:Q251	2.66	Yes	No	0	5	5
257	R:R:L221	R:R:L269	2.77	Yes	No	0	5	6
258	R:R:L221	R:R:V278	4.47	Yes	No	0	5	6
259	R:R:L221	R:R:M280	4.24	Yes	Yes	0	5	5
260	R:R:A222	R:R:V232	3.39	No	No	0	5	5
261	R:R:N283	R:R:S223	4.47	No	No	0	5	6
262	R:R:D286	R:R:S223	4.42	No	No	0	4	6
263	R:R:E224	R:R:K252	2.7	No	No	0	6	5
264	R:R:E224	R:R:R255	9.3	No	No	0	6	3
265	R:R:G228	R:R:Y227	4.35	No	Yes	1	8	7
266	R:R:F281	R:R:Y227	6.19	Yes	Yes	1	7	7
267	R:R:S308	R:R:Y227	6.36	Yes	Yes	1	8	7
268	R:R:D309	R:R:Y227	8.05	Yes	Yes	1	8	7
269	R:R:S310	R:R:Y227	8.9	No	Yes	1	6	7
270	R:R:F281	R:R:G228	3.01	Yes	No	1	7	8
271	R:R:E229	R:R:K252	13.5	No	No	0	6	5
272	R:R:F281	R:R:G231	4.52	Yes	No	0	7	7
273	R:R:F281	R:R:V232	3.93	Yes	No	0	7	5
274	R:R:E233	R:R:Q237	6.37	No	No	0	6	4
275	R:R:F235	R:R:I279	5.02	No	No	0	5	7
276	R:R:I247	R:R:T236	4.56	No	No	0	6	3
277	R:R:S239	R:R:V245	4.85	No	No	0	7	7
278	R:R:R240	S:S:R268	7.46	No	Yes	0	3	4
279	R:R:E241	R:R:I242	4.1	No	No	0	4	4
280	R:R:G243	R:R:I242	3.53	No	No	0	8	4
281	R:R:C246	R:R:V532	5.12	No	No	0	9	6
282	R:R:C246	R:R:C534	7.28	No	No	0	9	9
283	R:R:L269	R:R:Q249	2.66	No	No	0	6	6
284	R:R:Q249	R:R:T272	5.67	No	Yes	0	6	3
285	R:R:Q251	R:R:R268	18.69	No	Yes	0	5	4
286	R:R:I253	R:R:P254	3.39	No	No	0	6	4
287	R:R:D286	R:R:I253	7	No	No	0	4	6
288	R:R:E261	R:R:P254	9.43	No	No	0	4	4
289	R:R:E256	R:R:R255	9.3	No	No	0	3	3
290	R:R:E261	R:R:P257	3.14	No	No	0	4	3
291	R:R:F262	R:R:P257	4.33	No	No	0	3	3
292	R:R:E261	R:R:I265	4.1	No	No	0	4	5
293	R:R:F262	R:R:R289	19.24	No	No	0	3	2
294	R:R:F262	R:R:I290	5.02	No	No	0	3	4
295	R:R:E263	R:R:K267	2.7	No	No	17	3	3
296	R:R:E263	R:R:K296	8.1	No	No	17	3	3
297	R:R:E263	R:R:L297	5.3	No	Yes	17	3	3
298	R:R:I265	R:R:I290	2.94	No	No	0	5	4
299	R:R:I266	R:R:L297	2.85	No	Yes	0	4	3
300	R:R:K267	R:R:L297	7.05	No	Yes	17	3	3
301	R:R:R268	S:S:R240	7.46	Yes	No	0	4	3
302	R:R:F303	R:R:L269	4.87	Yes	No	0	7	6
303	R:R:L270	R:R:Q299	11.98	No	No	4	3	4
304	R:R:H302	R:R:L270	3.86	No	No	4	4	3
305	R:R:A275	R:R:T272	3.36	No	Yes	12	7	3
306	R:R:R276	R:R:S514	2.64	No	No	0	6	9
307	R:R:A277	R:R:S514	3.42	No	No	1	8	9
308	R:R:F303	R:R:V278	2.62	Yes	No	4	7	6
309	R:R:V278	R:R:W305	4.9	No	Yes	4	6	7
310	R:R:I279	R:R:I306	5.89	No	No	0	7	7
311	R:R:A282	R:R:M280	3.22	No	Yes	0	5	5
312	R:R:I287	R:R:M280	5.83	Yes	Yes	0	4	5
313	R:R:M280	R:R:W305	3.49	Yes	Yes	0	5	7
314	R:R:F281	R:R:S308	10.57	Yes	Yes	1	7	8
315	R:R:E284	R:R:K314	9.45	No	No	0	3	5
316	R:R:I287	R:R:L291	2.85	Yes	Yes	0	4	4
317	R:R:I287	R:R:W311	11.74	Yes	Yes	0	4	6
318	R:R:I287	R:R:P317	3.39	Yes	No	0	4	3
319	R:R:L291	R:R:W305	5.69	Yes	Yes	4	4	7
320	R:R:L291	R:R:Q321	5.32	Yes	Yes	4	4	3
321	R:R:I324	R:R:L291	5.71	Yes	Yes	4	4	4
322	R:R:E292	R:R:Q321	6.37	No	Yes	0	3	3
323	R:R:A294	R:R:I324	3.25	No	Yes	0	4	4
324	R:R:E323	R:R:K295	2.7	No	No	0	3	2
325	R:R:K296	R:R:L297	2.82	No	Yes	17	3	3
326	R:R:H302	R:R:Q299	4.95	No	No	4	4	4
327	R:R:F303	R:R:Q299	3.51	Yes	No	4	7	4
328	R:R:I324	R:R:S300	3.1	Yes	No	0	4	5
329	R:R:F303	R:R:H302	7.92	Yes	No	4	7	4
330	R:R:F303	R:R:W305	10.02	Yes	Yes	4	7	7
331	R:R:L304	R:R:W504	5.69	No	Yes	1	7	7
332	R:R:W305	R:R:W311	3.75	Yes	Yes	4	7	6
333	R:R:A328	R:R:W305	3.89	No	Yes	4	7	7
334	R:R:D309	R:R:S308	2.94	Yes	Yes	1	8	8
335	R:R:S308	R:R:S310	3.26	Yes	No	1	8	6
336	R:R:D309	R:R:S310	2.94	Yes	No	1	8	6
337	R:R:A328	R:R:W311	3.89	No	Yes	4	7	6
338	R:R:T330	R:R:W311	7.28	Yes	Yes	4	6	6
339	R:R:W311	R:R:Y485	6.75	Yes	Yes	4	6	4
340	R:R:G312	R:R:T330	3.64	No	Yes	0	5	6
341	R:R:G312	R:R:L332	5.13	No	No	0	5	5
342	R:R:F474	R:R:S313	7.93	Yes	No	4	5	4
343	R:R:S313	R:R:Y485	7.63	No	Yes	4	4	4
344	R:R:K314	R:R:P317	3.35	No	No	0	5	3
345	R:R:V318	R:R:Y476	3.79	No	Yes	0	4	5
346	R:R:Q320	R:R:Y319	14.65	No	No	0	2	3
347	R:R:I324	R:R:Q321	2.74	Yes	Yes	4	4	3
348	R:R:E322	R:R:Y476	6.73	No	Yes	4	4	5
349	R:R:E322	R:R:I478	2.73	No	Yes	4	4	2
350	R:R:E326	R:R:I478	16.4	No	Yes	0	5	2
351	R:R:G327	R:R:Q475	4.93	No	Yes	0	8	8
352	R:R:Q475	R:R:V329	4.3	Yes	No	0	8	6
353	R:R:F474	R:R:T330	3.89	Yes	Yes	4	5	6
354	R:R:T330	R:R:Y485	3.75	Yes	Yes	4	6	4
355	R:R:I331	R:R:Y471	3.63	Yes	Yes	1	6	8
356	R:R:L332	R:R:P333	3.28	No	No	0	5	4
357	R:R:F474	R:R:L332	8.53	Yes	No	0	5	5
358	R:R:F404	R:R:P333	2.89	Yes	No	0	7	4
359	R:R:P333	R:R:Y471	4.17	No	Yes	0	4	8
360	R:R:K334	R:R:R470	12.38	No	No	0	5	4
361	R:R:D472	R:R:K334	12.44	No	No	0	7	5
362	R:R:H490	R:R:K334	2.62	No	No	0	2	5
363	R:R:G400	R:R:R335	6	No	No	0	6	5
364	R:R:Q398	R:R:S337	2.89	No	No	0	6	3
365	R:R:I338	R:R:S454	3.1	No	Yes	0	6	4
366	R:R:G340	R:R:R343	6	No	No	0	5	4
367	R:R:F341	R:R:Q398	9.37	Yes	No	0	8	6
368	R:R:F341	R:R:V402	7.87	Yes	No	22	8	6
369	R:R:D342	R:R:Y396	6.9	No	Yes	0	4	5
370	R:R:D342	R:R:Q398	14.36	No	No	0	4	6
371	R:R:R348	R:R:Y344	18.52	Yes	Yes	0	5	7
372	R:R:R355	R:R:Y344	3.09	Yes	Yes	0	4	7
373	R:R:F345	R:R:F362	3.22	Yes	Yes	1	6	6
374	R:R:F345	R:R:Y396	11.35	Yes	Yes	1	6	5
375	R:R:A391	R:R:R346	6.91	No	No	1	3	4
376	R:R:R346	R:R:Y396	3.09	No	Yes	1	4	5
377	R:R:R348	R:R:S347	3.95	Yes	No	0	5	5
378	R:R:N352	R:R:R348	7.23	No	Yes	0	3	5
379	R:R:N353	R:R:R348	13.26	Yes	Yes	0	3	5
380	R:R:N352	R:R:T349	7.31	No	No	0	3	5
381	R:R:L350	R:R:W363	10.25	No	Yes	0	6	8
382	R:R:N353	R:R:N356	4.09	Yes	Yes	1	3	8
383	R:R:F359	R:R:N353	10.87	Yes	Yes	1	5	3
384	R:R:F359	R:R:N356	6.04	Yes	Yes	1	5	8
385	R:R:V357	R:R:W358	9.81	No	No	0	1	4
386	R:R:F359	R:R:F362	5.36	Yes	Yes	1	5	6
387	R:R:F359	R:R:W363	5.01	Yes	Yes	1	5	8
388	R:R:E361	R:R:E365	3.81	No	No	5	5	2
389	R:R:F362	R:R:N366	8.46	Yes	Yes	1	6	3
390	R:R:F367	R:R:W363	19.04	Yes	Yes	1	7	8
391	R:R:E388	R:R:W363	7.63	Yes	Yes	1	7	8
392	R:R:E364	R:R:K370	4.05	No	No	0	6	4
393	R:R:E364	R:R:L371	6.63	No	No	0	6	3
394	R:R:F367	R:R:N366	8.46	Yes	Yes	1	7	3
395	R:R:N366	R:R:S394	4.47	Yes	No	1	3	3
396	R:R:E388	R:R:F367	7	Yes	Yes	1	7	7
397	R:R:F367	R:R:S394	5.28	Yes	No	1	7	3
398	R:R:C369	R:R:C384	7.28	No	No	0	8	9
399	R:R:I381	R:R:K370	2.91	No	No	0	1	4
400	R:R:C384	R:R:L371	7.94	No	No	0	9	3
401	R:R:L387	R:R:T385	2.95	No	No	0	4	5
402	R:R:E388	R:R:T385	7.06	Yes	No	0	7	5
403	R:R:D393	R:R:E388	5.2	No	Yes	0	4	7
404	R:R:R389	R:R:R392	12.79	No	No	0	4	2
405	R:R:A391	R:R:Y396	4	No	Yes	1	3	5
406	R:R:E399	R:R:K401	4.05	Yes	No	1	5	4
407	R:R:I406	R:R:V402	3.07	No	No	0	8	6
408	R:R:F404	R:R:Q403	4.68	Yes	Yes	0	7	7
409	R:R:D407	R:R:Q403	6.53	Yes	Yes	23	8	7
410	R:R:Q403	R:R:S454	2.89	Yes	Yes	23	7	4
411	R:R:A455	R:R:Q403	4.55	No	Yes	0	4	7
412	R:R:I406	R:R:S454	4.64	No	Yes	0	8	4
413	R:R:D407	R:R:G453	5.03	Yes	No	0	8	6
414	R:R:D407	R:R:S454	4.42	Yes	Yes	23	8	4
415	R:R:D407	R:R:V459	4.38	Yes	No	0	8	6
416	R:R:F451	R:R:S411	5.28	Yes	No	0	9	8
417	R:R:F461	R:R:S411	3.96	Yes	No	0	8	8
418	R:R:I446	R:R:M412	2.92	Yes	Yes	21	6	7
419	R:R:F451	R:R:Y414	15.47	Yes	No	0	9	7
420	R:R:A415	R:R:I446	3.25	No	Yes	0	8	6
421	R:R:L416	R:R:L442	4.15	No	Yes	0	8	6
422	R:R:H417	R:R:N418	3.83	No	No	0	7	4
423	R:R:H417	R:R:K421	2.62	No	No	0	7	3
424	R:R:L423	R:R:M419	2.83	Yes	Yes	7	4	5
425	R:R:M419	R:R:M434	4.33	Yes	Yes	7	5	4
426	R:R:E441	R:R:M419	4.06	Yes	Yes	7	6	5
427	R:R:L442	R:R:M419	4.24	Yes	Yes	0	6	5
428	R:R:M419	R:R:Y445	9.58	Yes	Yes	7	5	4
429	R:R:C424	R:R:H420	4.42	Yes	No	7	6	3
430	R:R:H420	R:R:M434	5.25	No	Yes	7	3	4
431	R:R:D422	R:R:Y445	11.49	No	Yes	0	3	4
432	R:R:L423	R:R:R433	7.29	Yes	No	0	4	3
433	R:R:E441	R:R:L423	9.28	Yes	Yes	7	6	4
434	R:R:L423	R:R:Y445	3.52	Yes	Yes	7	4	4
435	R:R:C424	R:R:C431	7.28	Yes	No	0	6	6
436	R:R:C424	R:R:M434	4.86	Yes	Yes	7	6	4
437	R:R:C431	R:R:Y427	2.69	No	No	0	6	1
438	R:R:L430	R:R:M434	8.48	No	Yes	0	3	4
439	R:R:C431	R:R:P432	3.77	No	No	0	6	3
440	R:R:I437	R:R:M434	2.92	No	Yes	0	3	4
441	R:R:I437	R:R:L442	4.28	No	Yes	0	3	6
442	R:R:D438	R:R:E441	6.5	No	Yes	0	4	6
443	R:R:E441	R:R:Y445	6.73	Yes	Yes	7	6	4
444	R:R:L443	R:R:R447	10.93	No	No	0	5	5
445	R:R:G465	R:R:R447	6	No	No	16	7	5
446	R:R:F451	R:R:V449	2.62	Yes	No	0	9	7
447	R:R:F461	R:R:V449	2.62	Yes	No	0	8	7
448	R:R:N450	R:R:T460	5.85	No	No	0	5	3
449	R:R:F451	R:R:G453	3.01	Yes	No	0	9	6
450	R:R:F451	R:R:V459	7.87	Yes	No	0	9	6
451	R:R:N452	R:R:P458	3.26	No	No	0	5	3
452	R:R:P468	R:R:T460	3.5	No	No	0	3	3
453	R:R:F461	R:R:G465	3.01	Yes	No	16	8	7
454	R:R:E463	R:R:N462	3.94	No	No	0	4	7
455	R:R:E463	R:R:N464	9.2	No	No	0	4	6
456	R:R:R470	R:R:T492	5.17	No	No	0	4	5
457	R:R:W491	R:R:Y471	3.86	Yes	Yes	1	6	8
458	R:R:I473	R:R:I488	4.42	No	No	0	8	8
459	R:R:F474	R:R:Y485	5.16	Yes	Yes	4	5	4
460	R:R:F474	R:R:V487	3.93	Yes	No	0	5	5
461	R:R:Q475	R:R:Q477	8.96	Yes	No	0	8	6
462	R:R:M502	R:R:Q475	6.8	Yes	Yes	1	7	8
463	R:R:Q475	R:R:W504	7.67	Yes	Yes	1	8	7
464	R:R:I478	R:R:Y476	3.63	Yes	Yes	4	2	5
465	R:R:T483	R:R:Y476	9.99	No	Yes	4	4	5
466	R:R:Y476	R:R:Y485	11.91	Yes	Yes	4	5	4
467	R:R:K486	R:R:Q477	9.49	No	No	0	5	6
468	R:R:Q477	R:R:Q503	8.96	No	No	0	6	3
469	R:R:I478	R:R:T483	4.56	Yes	No	4	2	4
470	R:R:Q503	R:R:T479	5.67	No	No	0	3	3
471	R:R:E484	R:R:K486	6.75	No	No	0	2	5
472	R:R:I488	R:R:L497	2.85	No	No	1	8	6
473	R:R:I488	R:R:M502	2.92	No	Yes	1	8	7
474	R:R:H490	R:R:T492	4.11	No	No	0	2	5
475	R:R:H490	R:R:H496	14.33	No	No	0	2	3
476	R:R:L495	R:R:W491	4.56	Yes	Yes	1	7	6
477	R:R:L495	R:R:L497	5.54	Yes	No	1	7	6
478	R:R:L497	R:R:M502	2.83	No	Yes	1	6	7
479	R:R:E500	R:R:K498	4.05	No	No	24	4	5
480	R:R:D501	R:R:K498	2.77	No	No	24	3	5
481	R:R:D501	R:R:E500	3.9	No	No	24	3	4
482	R:R:M502	R:R:W504	8.14	Yes	Yes	1	7	7
483	R:R:P512	R:R:W504	17.57	No	Yes	0	8	7
484	R:R:H511	R:R:P512	7.63	Yes	No	0	4	8
485	R:R:C516	R:R:S517	3.44	No	No	0	9	9
486	R:R:C516	R:R:C535	7.28	No	Yes	12	9	9
487	R:R:S517	R:R:W536	13.59	No	No	0	9	7
488	R:R:L518	R:R:P519	3.28	No	No	0	4	6
489	R:R:C520	R:R:E524	7.6	No	No	25	9	7
490	R:R:C520	R:R:W536	2.61	No	No	0	9	7
491	R:R:C520	R:R:C538	7.28	No	No	25	9	9
492	R:R:K521	R:R:P522	5.02	No	No	0	1	4
493	R:R:E524	R:R:G523	3.27	No	No	0	7	9
494	R:R:G523	R:R:Q547	6.58	No	No	0	9	3
495	R:R:C538	R:R:E524	3.04	No	No	25	9	7
496	R:R:K527	R:R:R525	4.95	No	No	0	5	6
497	R:R:E539	R:R:R525	6.98	No	No	0	4	6
498	R:R:K526	R:R:W536	16.24	No	No	0	8	7
499	R:R:H537	R:R:V529	2.77	No	No	0	6	5
500	R:R:R540	R:R:R566	11.73	No	No	0	3	6
501	R:R:C541	R:R:C553	7.28	No	No	0	9	9
502	R:R:E542	R:R:Y544	3.37	No	Yes	0	5	8
503	R:R:E542	R:R:N545	14.46	No	No	0	5	7
504	R:R:G543	R:R:R566	6	No	No	0	5	6
505	R:R:L555	R:R:Y544	3.52	No	Yes	26	4	8
506	R:R:P557	R:R:Y544	5.56	No	Yes	26	4	8
507	R:R:R729	R:R:Y544	9.26	No	Yes	0	4	8
508	R:R:C553	R:R:N545	3.15	No	No	0	9	7
509	R:R:L555	R:R:N545	5.49	No	No	0	4	7
510	R:R:V548	R:R:Y546	6.31	No	No	0	5	8
511	R:R:E554	R:R:Y546	8.98	No	No	0	3	8
512	R:R:C556	R:R:Y546	4.03	No	No	0	9	8
513	R:R:E550	R:R:Q547	3.82	No	No	0	7	3
514	R:R:Q547	R:R:T567	14.17	No	No	0	3	5
515	R:R:D549	R:R:V548	2.92	No	No	27	8	5
516	R:R:S552	R:R:V548	4.85	No	No	27	5	5
517	R:R:D549	R:R:L551	9.5	No	No	0	8	3
518	R:R:D549	R:R:S552	5.89	No	No	27	8	5
519	R:R:L555	R:R:P557	9.85	No	No	26	4	4
520	R:R:C556	R:R:C569	7.28	No	No	0	9	9
521	R:R:P557	R:R:P562	9.74	No	No	0	4	8
522	R:R:L558	R:R:Q560	6.65	No	Yes	0	4	5
523	R:R:D559	R:R:Q560	3.92	No	Yes	0	5	5
524	R:R:D559	R:R:Y725	6.9	No	Yes	0	5	4
525	R:R:C569	R:R:Q560	3.05	No	Yes	0	9	5
526	R:R:I572	R:R:Q560	4.12	No	Yes	0	8	5
527	R:R:Q570	R:R:R561	7.01	No	Yes	0	5	6
528	R:R:P573	R:R:R561	4.32	No	Yes	0	4	6
529	R:R:P733	R:R:R561	5.76	Yes	Yes	18	5	6
530	R:R:E734	R:R:R561	6.98	No	Yes	18	5	6
531	R:R:P562	R:R:P733	7.79	No	Yes	0	8	5
532	R:R:M564	R:R:N563	4.21	No	Yes	0	3	7
533	R:R:N563	R:R:N565	14.98	Yes	No	0	7	4
534	R:R:G568	R:R:N563	3.39	No	Yes	0	2	7
535	R:R:N563	R:R:Q570	5.28	Yes	No	0	7	5
536	R:R:N565	R:R:T567	10.24	No	No	0	4	5
537	R:R:I572	R:R:P573	3.39	No	No	0	8	4
538	R:R:I572	R:R:Y725	13.3	No	Yes	0	8	4
539	R:R:P573	R:R:R737	10.09	No	No	0	4	4
540	R:R:I574	R:R:I723	2.94	No	No	0	5	4
541	R:R:G738	R:R:I574	3.53	No	No	0	8	5
542	R:R:I575	R:R:R737	3.76	No	No	0	6	4
543	R:R:I575	R:R:V739	4.61	No	No	0	6	6
544	R:R:E578	R:R:K576	8.1	No	No	0	6	5
545	R:R:I640	R:R:L577	2.85	No	No	0	8	8
546	R:R:L577	R:R:P643	3.28	No	No	0	8	9
547	R:R:L577	R:R:Y812	4.69	No	No	0	8	7
548	R:R:E578	R:R:H580	3.69	No	No	0	6	3
549	R:R:A642	R:R:E578	3.02	No	No	0	5	6
550	R:R:V588	R:R:W579	3.68	No	No	0	4	6
551	R:R:P582	R:R:S581	3.56	No	No	0	4	7
552	R:R:S581	R:R:V585	4.85	No	No	0	7	6
553	R:R:P582	R:R:W583	2.7	No	Yes	0	4	6
554	R:R:W583	R:R:Y812	4.82	Yes	No	0	6	7
555	R:R:T816	R:R:W583	3.64	No	Yes	0	8	6
556	R:R:W583	W:W:?1	9.32	Yes	Yes	0	6	0
557	R:R:A584	R:R:I640	3.25	No	No	0	7	8
558	R:R:P587	R:R:V586	3.53	No	No	0	8	4
559	R:R:P587	R:R:T819	6.99	No	No	0	8	7
560	R:R:F637	R:R:V588	5.24	No	No	0	7	4
561	R:R:A591	R:R:F637	4.16	No	No	0	7	7
562	R:R:I592	R:R:I596	2.94	No	No	0	4	3
563	R:R:G594	R:R:Y633	7.24	No	Yes	0	6	8
564	R:R:F630	R:R:I595	5.02	No	No	0	4	6
565	R:R:I595	R:R:Y633	3.63	No	Yes	0	6	8
566	R:R:F630	R:R:T598	3.89	No	No	0	4	7
567	R:R:T598	R:R:Y633	6.24	No	Yes	0	7	8
568	R:R:L830	R:R:T598	4.42	Yes	No	0	8	7
569	R:R:F600	R:R:T604	7.78	No	No	0	2	6
570	R:R:F600	R:R:V838	3.93	No	No	0	2	7
571	R:R:F605	R:R:V601	3.93	No	No	29	9	5
572	R:R:V601	R:R:V838	4.81	No	No	29	5	7
573	R:R:I602	R:R:V606	3.07	No	No	0	4	4
574	R:R:I602	R:R:Y623	4.84	No	No	0	4	7
575	R:R:I602	R:R:L626	4.28	No	No	0	4	9
576	R:R:I841	R:R:T604	3.04	Yes	No	0	9	6
577	R:R:I842	R:R:T604	6.08	No	No	0	6	6
578	R:R:F605	R:R:Y834	5.16	No	Yes	0	9	9
579	R:R:F605	R:R:V838	3.93	No	No	29	9	7
580	R:R:R607	R:R:Y608	16.46	No	No	0	4	5
581	R:R:T611	R:R:Y608	4.99	Yes	No	10	9	5
582	R:R:I841	R:R:Y608	3.63	Yes	No	10	9	5
583	R:R:P612	R:R:T611	3.5	No	Yes	10	8	9
584	R:R:I613	R:R:T611	3.04	Yes	Yes	10	7	9
585	R:R:T611	R:R:V614	4.76	Yes	No	0	9	9
586	R:R:I841	R:R:T611	3.04	Yes	Yes	10	9	9
587	R:R:N848	R:R:T611	7.31	No	Yes	10	9	9
588	R:R:P612	R:R:R615	10.09	No	No	0	8	8
589	R:R:N848	R:R:P612	11.4	No	No	10	9	8
590	R:R:I613	R:R:K837	5.82	Yes	No	0	7	9
591	R:R:I613	R:R:I841	2.94	Yes	Yes	10	7	9
592	R:R:K837	R:R:S617	6.12	No	No	0	9	9
593	R:R:E620	R:R:Q695	12.74	No	No	0	6	8
594	R:R:T627	R:R:Y623	4.99	No	No	0	5	7
595	R:R:T699	R:R:V624	3.17	Yes	No	0	7	7
596	R:R:A665	R:R:L625	4.73	No	No	0	7	8
597	R:R:L625	R:R:L666	5.54	No	No	0	8	7
598	R:R:L626	R:R:L830	2.77	No	Yes	0	9	8
599	R:R:L626	R:R:Y834	7.03	No	Yes	0	9	9
600	R:R:F661	R:R:G628	4.52	No	No	0	7	8
601	R:R:I629	R:R:Y633	4.84	No	Yes	0	8	8
602	R:R:I629	R:R:S662	7.74	No	No	0	8	7
603	R:R:I629	R:R:L830	9.99	No	Yes	0	8	8
604	R:R:L631	R:R:S634	3	No	No	0	5	6
605	R:R:L631	R:R:L657	4.15	No	No	0	5	7
606	R:R:G658	R:R:L631	5.13	No	No	0	7	5
607	R:R:C632	R:R:S662	5.16	Yes	No	0	6	7
608	R:R:C632	R:R:M822	3.24	Yes	No	0	6	8
609	R:R:A826	R:R:C632	3.61	No	Yes	0	8	6
610	R:R:S827	R:R:Y633	6.36	No	Yes	0	6	8
611	R:R:I635	R:R:L655	7.14	No	Yes	0	6	7
612	R:R:I635	R:R:M822	2.92	No	No	0	6	8
613	R:R:T636	R:R:T819	4.71	Yes	No	0	7	7
614	R:R:M822	R:R:T636	3.01	No	Yes	0	8	7
615	R:R:S823	R:R:T636	9.59	No	Yes	0	8	7
616	R:R:I647	R:R:L638	4.28	No	No	0	6	5
617	R:R:L638	R:R:R651	4.86	No	No	0	5	8
618	R:R:M639	R:R:T815	3.01	No	No	0	8	8
619	R:R:A642	R:R:D644	3.09	No	No	0	5	5
620	R:R:L740	R:R:P643	8.21	No	No	0	6	9
621	R:R:C742	R:R:P643	3.77	No	No	0	9	9
622	R:R:D644	R:R:I647	2.8	No	No	0	5	6
623	R:R:C648	R:R:R652	2.79	No	Yes	13	9	9
624	R:R:C648	R:R:C742	7.28	No	No	13	9	9
625	R:R:F650	R:R:S649	6.61	No	No	31	6	5
626	R:R:P719	R:R:S649	8.91	Yes	No	31	8	5
627	R:R:F650	R:R:P719	5.78	No	Yes	31	6	8
628	R:R:R651	R:R:R652	5.33	No	Yes	0	8	9
629	R:R:F654	R:R:R651	3.21	No	No	0	4	8
630	R:R:L655	R:R:R652	6.07	Yes	Yes	13	7	9
631	R:R:F714	R:R:R652	5.34	No	Yes	0	7	9
632	R:R:C742	R:R:R652	2.79	No	Yes	13	9	9
633	R:R:I744	R:R:R652	6.26	No	Yes	0	5	9
634	R:R:L749	R:R:R652	3.64	No	Yes	13	7	9
635	R:R:F654	R:R:V653	2.62	No	Yes	0	4	5
636	R:R:V653	R:R:V710	3.21	Yes	No	32	5	6
637	R:R:F714	R:R:V653	5.24	No	Yes	0	7	5
638	R:R:L655	R:R:L749	2.77	Yes	No	13	7	7
639	R:R:F661	R:R:L657	9.74	No	No	30	7	7
640	R:R:I703	R:R:L657	2.85	No	No	30	7	7
641	R:R:M659	R:R:Y663	5.99	No	Yes	0	8	7
642	R:R:L753	R:R:M659	2.83	No	No	0	8	8
643	R:R:M659	R:R:S756	10.73	No	No	0	8	7
644	R:R:C660	R:R:Q706	6.1	No	No	33	7	9
645	R:R:C660	R:R:S756	5.16	No	No	0	7	7
646	R:R:C660	R:R:L759	3.17	No	Yes	33	7	9
647	R:R:F661	R:R:I703	10.05	No	No	30	7	7
648	R:R:S662	R:R:Y663	5.09	No	Yes	0	7	7
649	R:R:M760	R:R:Y663	23.95	No	Yes	0	8	7
650	R:R:S825	R:R:Y663	5.09	No	Yes	0	9	7
651	R:R:A664	R:R:L759	4.73	No	Yes	0	9	9
652	R:R:L666	R:R:T764	8.84	No	No	0	7	8
653	R:R:Q695	R:R:T699	2.83	No	Yes	0	8	7
654	R:R:F700	R:R:L696	4.87	No	No	0	2	6
655	R:R:L702	R:R:L759	4.15	No	Yes	0	5	9
656	R:R:L759	R:R:Q706	6.65	Yes	No	33	9	9
657	R:R:G709	R:R:V712	3.68	No	No	0	7	4
658	R:R:V710	R:R:W713	8.58	No	No	0	6	7
659	R:R:F711	R:R:V715	7.87	No	No	0	3	2
660	R:R:C751	R:R:W713	7.84	No	No	0	3	7
661	R:R:H720	R:R:I721	2.65	No	No	0	4	5
662	R:R:D743	R:R:H720	5.04	No	No	0	7	4
663	R:R:I722	R:R:K741	2.91	No	No	0	3	6
664	R:R:D743	R:R:I722	5.6	No	No	0	7	3
665	R:R:I723	R:R:Y725	8.46	No	Yes	0	4	4
666	R:R:D724	R:R:Q728	9.14	No	No	28	7	5
667	R:R:D724	R:R:V739	4.38	No	No	28	7	6
668	R:R:G738	R:R:Y725	2.9	No	Yes	0	8	4
669	R:R:E727	R:R:G726	3.27	No	No	0	5	2
670	R:R:Q728	R:R:V739	2.87	No	No	28	5	6
671	R:R:A736	R:R:T730	3.36	No	No	0	4	5
672	R:R:D732	R:R:P733	4.83	No	Yes	18	5	5
673	R:R:D732	R:R:E734	16.89	No	No	18	5	5
674	R:R:D732	R:R:K735	11.06	No	No	0	5	3
675	R:R:E734	R:R:P733	4.72	No	Yes	18	5	5
676	R:R:K741	R:R:M811	7.2	No	No	0	6	5
677	R:R:S745	R:R:S748	4.89	No	No	0	8	6
678	R:R:D746	R:R:L747	5.43	No	No	0	3	3
679	R:R:D746	R:R:K810	2.77	No	Yes	0	3	5
680	R:R:I750	R:R:L747	2.85	Yes	No	0	5	3
681	R:R:L749	R:R:L818	2.77	No	No	0	7	8
682	R:R:I750	R:R:L753	2.85	Yes	No	0	5	8
683	R:R:F801	R:R:I750	7.54	Yes	Yes	34	8	5
684	R:R:F802	R:R:I750	3.77	No	Yes	34	6	5
685	R:R:G754	R:R:I757	3.53	No	No	0	6	5
686	R:R:C763	R:R:L759	3.17	No	Yes	0	8	9
687	R:R:M760	R:R:T790	4.52	No	No	0	8	9
688	R:R:M760	R:R:W794	4.65	No	No	0	8	9
689	R:R:T762	R:R:V761	4.76	No	No	0	4	3
690	R:R:A780	R:R:F777	4.16	No	No	0	9	9
691	R:R:E779	R:R:I783	2.73	No	No	0	9	9
692	R:R:E779	R:R:L833	3.98	No	No	0	9	8
693	R:R:K781	R:R:P782	5.02	No	No	0	9	5
694	R:R:F785	R:R:K781	8.69	Yes	No	0	8	9
695	R:R:I783	R:R:M787	2.92	No	No	0	9	9
696	R:R:G784	R:R:Y788	4.35	No	No	0	9	9
697	R:R:F785	R:R:M832	3.73	Yes	No	0	8	6
698	R:R:F785	S:S:F785	4.29	Yes	Yes	0	8	8
699	R:R:T786	R:R:T789	3.14	No	Yes	35	9	7
700	R:R:S829	R:R:T786	3.2	No	No	0	7	9
701	R:R:M832	R:R:T786	4.52	No	No	35	6	9
702	R:R:T789	R:R:V828	4.76	Yes	No	0	7	8
703	R:R:M832	R:R:T789	4.52	No	Yes	35	6	7
704	R:R:S829	R:R:T790	3.2	No	No	0	7	9
705	R:R:C791	R:R:L795	3.17	No	No	0	6	6
706	R:R:I792	S:S:I792	7.36	No	No	0	8	8
707	R:R:I793	R:R:L824	4.28	No	No	0	8	7
708	R:R:I793	R:R:S825	3.1	No	No	0	8	9
709	R:R:I793	R:R:V828	4.61	No	No	0	8	8
710	R:R:F797	R:R:W794	17.04	Yes	No	0	9	9
711	R:R:S825	R:R:W794	8.65	No	No	0	9	9
712	R:R:A796	X:X:?1	3.71	No	Yes	0	8	0
713	R:R:F797	R:R:I800	3.77	Yes	Yes	0	9	8
714	R:R:F797	R:R:F801	15	Yes	Yes	0	9	8
715	R:R:F797	R:R:S821	6.61	Yes	No	0	9	8
716	R:R:I798	R:R:P799	5.08	No	No	0	7	9
717	R:R:P799	S:S:I800	5.08	No	Yes	9	9	8
718	R:R:P799	X:X:?1	13.55	No	Yes	9	9	0
719	R:R:I800	R:R:T817	3.04	Yes	No	0	8	8
720	R:R:I800	S:S:P799	5.08	Yes	No	9	8	9
721	R:R:I800	S:S:I800	4.42	Yes	Yes	9	8	8
722	R:R:I800	W:W:?1	18.99	Yes	Yes	9	8	0
723	R:R:F801	R:R:F802	8.57	Yes	No	34	8	6
724	R:R:F801	R:R:Q814	19.91	Yes	No	0	8	7
725	R:R:F801	R:R:L818	9.74	Yes	No	0	8	8
726	R:R:T804	S:S:E809	11.29	No	Yes	0	8	8
727	R:R:A805	R:R:E809	3.02	No	Yes	0	6	8
728	R:R:K810	R:R:Q806	14.92	Yes	No	0	5	7
729	R:R:E809	R:R:S807	4.31	Yes	No	0	8	5
730	R:R:E809	R:R:I813	2.73	Yes	No	0	8	5
731	R:R:E809	S:S:T804	7.06	Yes	No	0	8	8
732	R:R:K810	R:R:M811	4.32	Yes	No	0	5	5
733	R:R:K810	R:R:Q814	5.42	Yes	No	0	5	7
734	R:R:I813	R:R:T817	3.04	No	No	0	5	8
735	R:R:I813	W:W:?1	4.38	No	Yes	0	5	0
736	R:R:Q814	R:R:T817	2.83	No	No	0	7	8
737	R:R:V820	W:W:?1	10.67	No	Yes	0	7	0
738	R:R:S821	W:W:?1	12.29	No	Yes	0	8	0
739	R:R:G831	R:R:L830	3.42	No	Yes	0	1	8
740	R:R:L833	R:R:Y834	15.24	No	Yes	0	8	9
741	R:R:M835	R:R:P836	3.35	No	No	0	3	9
742	R:R:F843	R:R:Y839	30.95	No	No	0	4	9
743	R:R:F843	R:R:I842	6.28	No	No	0	4	6
744	R:R:E846	R:R:H844	4.92	No	No	36	6	6
745	R:R:H844	R:R:Q847	8.65	No	No	36	6	5
746	R:R:E846	R:R:P845	4.72	No	No	0	6	8
747	R:R:E846	R:R:Q847	14.02	No	No	36	6	5
748	S:S:H38	S:S:S39	4.18	No	No	0	4	5
749	S:S:L103	S:S:S39	4.5	Yes	No	0	5	5
750	S:S:I102	S:S:I40	4.42	Yes	No	0	8	4
751	S:S:I40	S:S:N356	4.25	No	Yes	0	4	8
752	S:S:I40	S:S:W358	5.87	No	No	0	4	4
753	S:S:R101	S:S:R41	13.86	No	No	0	5	3
754	S:S:V100	S:S:V42	3.21	Yes	No	0	7	5
755	S:S:R355	S:S:V42	2.62	Yes	No	0	4	5
756	S:S:G44	S:S:T97	3.64	No	No	0	9	7
757	S:S:D45	S:S:T97	5.78	No	No	0	8	7
758	S:S:I46	S:S:L98	2.85	No	Yes	0	5	9
759	S:S:I46	S:S:S148	4.64	No	No	0	5	4
760	S:S:I46	S:S:L416	4.28	No	No	0	5	8
761	S:S:D145	S:S:I47	4.2	No	No	0	4	5
762	S:S:I147	S:S:I47	2.94	No	No	0	5	5
763	S:S:L48	S:S:M412	4.24	No	Yes	0	7	7
764	S:S:G50	S:S:M79	3.49	No	Yes	0	8	8
765	S:S:L51	S:S:T105	4.42	No	No	0	7	7
766	S:S:F119	S:S:L51	6.09	No	No	0	5	7
767	S:S:L51	S:S:V162	4.47	No	Yes	0	7	5
768	S:S:F52	S:S:L76	3.65	Yes	No	2	9	4
769	S:S:F52	S:S:M79	6.22	Yes	Yes	2	9	8
770	S:S:F52	S:S:Y176	8.25	Yes	Yes	2	9	7
771	S:S:F52	S:S:V405	2.62	Yes	No	2	9	8
772	S:S:A154	S:S:P53	3.74	No	No	0	5	5
773	S:S:H55	S:S:V54	4.15	Yes	No	6	8	5
774	S:S:D104	S:S:V54	11.69	No	No	6	9	5
775	S:S:V54	S:S:W358	6.13	No	No	0	5	4
776	S:S:C64	S:S:H55	2.95	No	Yes	6	9	8
777	S:S:H55	S:S:L67	6.43	Yes	No	6	8	3
778	S:S:D104	S:S:H55	6.3	No	Yes	6	9	8
779	S:S:C106	S:S:H55	4.42	Yes	Yes	6	7	8
780	S:S:E361	S:S:H55	6.15	No	Yes	6	5	8
781	S:S:A56	S:S:E66	3.02	No	No	0	3	3
782	S:S:A56	S:S:K68	4.82	No	No	0	3	5
783	S:S:K57	S:S:R108	11.14	No	No	0	2	4
784	S:S:E59	S:S:E66	5.07	No	No	0	1	3
785	S:S:P63	S:S:V62	3.53	No	No	0	2	1
786	S:S:P63	S:S:Y111	2.78	No	Yes	0	2	3
787	S:S:C106	S:S:C64	7.28	Yes	No	6	7	9
788	S:S:C64	S:S:Y111	5.38	No	Yes	6	9	3
789	S:S:E361	S:S:L67	11.93	No	No	6	5	3
790	S:S:E365	S:S:L67	7.95	No	No	6	2	3
791	S:S:K68	S:S:K71	8.62	No	Yes	0	5	5
792	S:S:K68	S:S:S107	4.59	No	No	0	5	3
793	S:S:F362	S:S:K69	7.44	Yes	No	2	6	4
794	S:S:K69	S:S:N366	4.2	No	Yes	2	4	3
795	S:S:K71	S:S:R75	3.71	Yes	Yes	2	5	4
796	S:S:E284	S:S:K71	4.05	No	Yes	0	3	5
797	S:S:F362	S:S:I73	8.79	Yes	No	0	6	7
798	S:S:F345	S:S:H74	6.79	Yes	No	2	6	7
799	S:S:H74	S:S:Y396	5.44	No	Yes	2	7	5
800	S:S:R75	S:S:Y176	6.17	Yes	Yes	2	4	7
801	S:S:E399	S:S:R75	13.96	Yes	Yes	2	5	4
802	S:S:K401	S:S:R75	8.66	No	Yes	2	4	4
803	S:S:E77	S:S:L76	3.98	Yes	No	2	8	4
804	S:S:L76	S:S:N356	4.12	No	Yes	2	4	8
805	S:S:E77	S:S:Y344	6.73	Yes	Yes	0	8	7
806	S:S:E77	S:S:F345	5.83	Yes	Yes	2	8	6
807	S:S:E77	S:S:N353	6.57	Yes	Yes	2	8	3
808	S:S:E77	S:S:N356	7.89	Yes	Yes	2	8	8
809	S:S:A78	S:S:F341	4.16	No	Yes	38	8	8
810	S:S:A78	S:S:V402	5.09	No	No	38	8	6
811	S:S:M79	S:S:V100	3.04	Yes	Yes	2	8	7
812	S:S:I102	S:S:M79	4.37	Yes	Yes	2	8	8
813	S:S:I151	S:S:M79	4.37	No	Yes	0	7	8
814	S:S:I102	S:S:L80	2.85	Yes	No	0	8	5
815	S:S:L80	S:S:R355	14.58	No	Yes	0	5	4
816	S:S:Q85	S:S:Y81	16.91	No	Yes	0	8	7
817	S:S:G340	S:S:Y81	2.9	No	Yes	0	5	7
818	S:S:F341	S:S:Y81	4.13	Yes	Yes	0	8	7
819	S:S:Y344	S:S:Y81	7.94	Yes	Yes	0	7	7
820	S:S:A82	S:S:I406	3.25	No	No	0	8	8
821	S:S:A82	S:S:V409	5.09	No	No	0	8	8
822	S:S:I83	S:S:L98	2.85	No	Yes	0	7	9
823	S:S:I83	S:S:V100	6.14	No	Yes	0	7	7
824	S:S:I83	S:S:V409	3.07	No	No	0	7	8
825	S:S:D84	S:S:R355	9.53	No	Yes	0	7	4
826	S:S:K88	S:S:Q85	5.42	No	No	0	5	8
827	S:S:I86	S:S:L98	2.85	No	Yes	0	9	9
828	S:S:I86	S:S:Y410	9.67	No	No	0	9	7
829	S:S:A413	S:S:I86	4.87	No	No	0	9	9
830	S:S:D89	S:S:P90	6.44	No	No	0	6	4
831	S:S:D89	S:S:L92	6.79	No	No	0	6	6
832	S:S:D91	S:S:P90	3.22	No	No	0	3	4
833	S:S:L92	S:S:Y414	7.03	No	No	0	6	7
834	S:S:H417	S:S:L92	5.14	No	No	0	7	6
835	S:S:L93	S:S:L98	4.15	No	Yes	0	9	9
836	S:S:I428	S:S:N95	2.83	No	No	0	4	8
837	S:S:H420	S:S:I96	2.65	No	No	0	3	5
838	S:S:I102	S:S:V100	6.14	Yes	Yes	2	8	7
839	S:S:L103	S:S:R101	3.64	Yes	No	0	5	5
840	S:S:L103	S:S:Q115	11.98	Yes	No	6	5	6
841	S:S:L103	S:S:T118	2.95	Yes	No	6	5	2
842	S:S:F119	S:S:L103	6.09	No	Yes	0	5	5
843	S:S:C106	S:S:D104	4.67	Yes	No	6	7	9
844	S:S:A112	S:S:T105	3.36	No	No	0	7	7
845	S:S:C106	S:S:Y111	5.38	Yes	Yes	6	7	3
846	S:S:D109	S:S:T110	2.89	No	No	0	4	3
847	S:S:D109	S:S:M161	5.54	No	No	0	4	6
848	S:S:Q115	S:S:Y111	6.76	No	Yes	6	6	3
849	S:S:L113	S:S:M161	9.9	No	No	0	5	6
850	S:S:I165	S:S:L113	2.85	No	No	0	5	5
851	S:S:Q115	S:S:T118	2.83	No	No	6	6	2
852	S:S:S116	S:S:V162	4.85	No	Yes	2	5	5
853	S:S:I165	S:S:S116	6.19	No	No	0	5	5
854	S:S:L166	S:S:S116	3	Yes	No	2	6	5
855	S:S:F119	S:S:V150	3.93	No	No	0	5	6
856	S:S:F169	S:S:V120	14.42	Yes	No	0	6	4
857	S:S:K146	S:S:L123	2.82	No	No	0	3	3
858	S:S:F169	S:S:L123	7.31	Yes	No	0	6	3
859	S:S:I437	S:S:S148	3.1	No	No	0	3	4
860	S:S:G149	S:S:M412	3.49	No	Yes	0	8	7
861	S:S:L166	S:S:V150	4.47	Yes	No	0	6	6
862	S:S:I151	S:S:V409	3.07	No	No	0	7	8
863	S:S:G152	S:S:Q173	4.93	No	Yes	0	8	8
864	S:S:A153	S:S:V158	3.39	No	No	0	5	3
865	S:S:A153	S:S:S159	3.42	No	Yes	0	5	8
866	S:S:A154	S:S:Y176	2.67	No	Yes	0	5	7
867	S:S:A155	S:S:V158	3.39	No	No	0	4	3
868	S:S:A180	S:S:S156	3.42	No	No	0	7	9
869	S:S:N226	S:S:S157	5.96	No	No	0	6	5
870	S:S:Q173	S:S:S159	2.89	Yes	Yes	2	8	8
871	S:S:S159	S:S:S175	3.26	Yes	No	2	8	8
872	S:S:S159	S:S:S178	6.52	Yes	No	2	8	8
873	S:S:F192	S:S:S159	2.64	Yes	Yes	2	8	8
874	S:S:E182	S:S:I160	6.83	No	Yes	2	4	5
875	S:S:I160	S:S:L183	4.28	Yes	Yes	2	5	8
876	S:S:I160	S:S:Y189	6.04	Yes	Yes	2	5	6
877	S:S:I160	S:S:N226	4.25	Yes	No	0	5	6
878	S:S:L166	S:S:V162	2.98	Yes	Yes	2	6	5
879	S:S:Q173	S:S:V162	5.73	Yes	Yes	2	8	5
880	S:S:A163	S:S:Q173	4.55	No	Yes	0	7	8
881	S:S:N164	S:S:Y189	4.65	No	Yes	0	5	6
882	S:S:I171	S:S:L166	5.71	No	Yes	0	6	6
883	S:S:L166	S:S:Q173	5.32	Yes	Yes	2	6	8
884	S:S:D190	S:S:R167	13.1	No	No	0	6	5
885	S:S:F191	S:S:K170	6.2	No	No	0	7	4
886	S:S:I171	S:S:P172	3.39	No	Yes	0	6	9
887	S:S:F191	S:S:P172	2.89	No	Yes	0	7	9
888	S:S:L442	S:S:P172	6.57	Yes	Yes	0	6	9
889	S:S:I446	S:S:P172	3.39	Yes	Yes	0	6	9
890	S:S:F192	S:S:Q173	8.2	Yes	Yes	2	8	8
891	S:S:A408	S:S:I174	3.25	No	No	0	9	7
892	S:S:I174	S:S:M412	7.29	No	Yes	37	7	7
893	S:S:I174	S:S:I446	2.94	No	Yes	37	7	6
894	S:S:S175	S:S:S178	6.52	No	No	2	8	8
895	S:S:F192	S:S:S175	3.96	Yes	No	2	8	8
896	S:S:A177	S:S:Y176	2.67	No	Yes	0	6	7
897	S:S:V405	S:S:Y176	8.83	No	Yes	2	8	7
898	S:S:A177	S:S:K401	3.21	No	No	0	6	4
899	S:S:T179	S:S:V196	3.17	Yes	Yes	0	7	7
900	S:S:D199	S:S:T179	10.12	Yes	Yes	0	8	7
901	S:S:D309	S:S:T179	2.89	Yes	Yes	2	8	7
902	S:S:D199	S:S:P181	6.44	Yes	No	0	8	5
903	S:S:P181	S:S:S200	3.56	No	No	0	5	3
904	S:S:E182	S:S:Y189	11.22	No	Yes	2	4	6
905	S:S:L183	S:S:Y189	7.03	Yes	Yes	2	8	6
906	S:S:F192	S:S:L183	19.49	Yes	Yes	2	8	8
907	S:S:L183	S:S:R194	6.07	Yes	Yes	2	8	9
908	S:S:R194	S:S:S184	5.27	Yes	No	2	9	8
909	S:S:P198	S:S:S184	3.56	Yes	No	2	7	8
910	S:S:D466	S:S:S184	8.83	Yes	No	2	8	8
911	S:S:D185	S:S:T187	7.23	No	No	0	7	2
912	S:S:N186	S:S:N464	6.81	No	No	0	7	6
913	S:S:R188	S:S:Y189	8.23	No	Yes	0	6	6
914	S:S:F191	S:S:L443	8.53	No	No	0	7	5
915	S:S:F192	S:S:R194	4.28	Yes	Yes	2	8	9
916	S:S:R447	S:S:S193	6.59	No	No	19	5	7
917	S:S:F461	S:S:S193	2.64	Yes	No	19	8	7
918	S:S:G465	S:S:S193	3.71	No	No	19	7	7
919	S:S:R194	S:S:V196	2.62	Yes	Yes	0	9	7
920	S:S:P198	S:S:R194	7.21	Yes	Yes	2	7	9
921	S:S:D466	S:S:R194	11.91	Yes	Yes	2	8	9
922	S:S:F404	S:S:V195	2.62	Yes	No	0	7	9
923	S:S:F461	S:S:V195	2.62	Yes	No	0	8	9
924	S:S:P197	S:S:V196	3.53	No	Yes	0	8	7
925	S:S:F404	S:S:V196	7.87	Yes	Yes	0	7	7
926	S:S:G469	S:S:P197	4.06	No	No	0	5	8
927	S:S:P197	S:S:Y471	8.34	No	Yes	0	8	8
928	S:S:P198	S:S:Y201	5.56	Yes	Yes	2	7	4
929	S:S:D466	S:S:P198	9.66	Yes	Yes	2	8	7
930	S:S:D199	S:S:Q202	5.22	Yes	Yes	0	8	9
931	S:S:D199	S:S:Y227	4.6	Yes	Yes	0	8	7
932	S:S:G469	S:S:Y201	4.35	No	Yes	0	5	4
933	S:S:Y201	S:S:Y471	2.98	Yes	Yes	2	4	8
934	S:S:W491	S:S:Y201	3.86	Yes	Yes	2	6	4
935	S:S:M206	S:S:Q202	2.72	No	Yes	2	7	9
936	S:S:F281	S:S:Q202	3.51	Yes	Yes	2	7	9
937	S:S:Q202	S:S:S308	4.33	Yes	Yes	2	9	8
938	S:S:D309	S:S:Q202	6.53	Yes	Yes	2	8	9
939	S:S:I331	S:S:Q202	2.74	Yes	Yes	2	6	9
940	S:S:Q204	S:S:V207	2.87	Yes	No	2	3	6
941	S:S:D208	S:S:Q204	7.83	No	Yes	2	5	3
942	S:S:I238	S:S:Q204	4.12	Yes	Yes	2	5	3
943	S:S:Q204	S:S:W491	3.29	Yes	Yes	2	3	6
944	S:S:A205	S:S:W491	9.08	No	Yes	0	8	6
945	S:S:F281	S:S:M206	6.22	Yes	No	2	7	7
946	S:S:I331	S:S:M206	2.92	Yes	No	2	6	7
947	S:S:F235	S:S:V207	5.24	No	No	0	5	6
948	S:S:I238	S:S:V207	6.14	Yes	No	2	5	6
949	S:S:D208	S:S:W491	6.7	No	Yes	2	5	6
950	S:S:D208	S:S:L495	2.71	No	Yes	2	5	7
951	S:S:I209	S:S:I331	2.94	No	Yes	0	8	6
952	S:S:I209	S:S:I473	5.89	No	No	0	8	8
953	S:S:I209	S:S:L495	2.85	No	Yes	0	8	7
954	S:S:V210	S:S:V245	3.21	No	No	0	7	7
955	S:S:L213	S:S:W215	7.97	Yes	Yes	2	7	9
956	S:S:L213	S:S:V499	2.98	Yes	No	0	7	4
957	S:S:L213	S:S:M502	4.24	Yes	Yes	2	7	7
958	S:S:H511	S:S:L213	7.71	Yes	Yes	2	4	7
959	S:S:A277	S:S:W215	3.89	No	Yes	2	8	9
960	S:S:L304	S:S:W215	4.56	No	Yes	2	7	9
961	S:S:I306	S:S:W215	3.52	No	Yes	0	7	9
962	S:S:W215	S:S:W504	4.69	Yes	Yes	2	9	7
963	S:S:H511	S:S:W215	4.23	Yes	Yes	2	4	9
964	S:S:S514	S:S:W215	4.94	No	Yes	2	9	9
965	S:S:N216	S:S:V515	5.91	No	No	0	7	5
966	S:S:A248	S:S:Y217	5.34	No	Yes	0	8	9
967	S:S:T272	S:S:Y217	4.99	Yes	Yes	14	3	9
968	S:S:A275	S:S:Y217	2.67	No	Yes	14	7	9
969	S:S:C516	S:S:Y217	16.13	No	Yes	14	9	9
970	S:S:C535	S:S:Y217	5.38	Yes	Yes	14	9	9
971	S:S:F235	S:S:V218	2.62	No	No	0	5	8
972	S:S:A277	S:S:V218	3.39	No	No	0	8	8
973	S:S:Q249	S:S:S219	2.89	No	No	0	6	8
974	S:S:T220	S:S:V232	4.76	No	No	0	5	5
975	S:S:I247	S:S:T220	3.04	No	No	0	6	5
976	S:S:S250	S:S:T220	3.2	No	No	0	5	5
977	S:S:L221	S:S:Q251	2.66	Yes	No	0	5	5
978	S:S:L221	S:S:L269	2.77	Yes	No	0	5	6
979	S:S:L221	S:S:V278	4.47	Yes	No	0	5	6
980	S:S:L221	S:S:M280	4.24	Yes	Yes	0	5	5
981	S:S:A222	S:S:V232	3.39	No	No	0	5	5
982	S:S:N283	S:S:S223	4.47	No	No	0	5	6
983	S:S:D286	S:S:S223	4.42	No	No	0	4	6
984	S:S:E224	S:S:K252	2.7	No	No	0	6	5
985	S:S:E224	S:S:R255	9.3	No	No	0	6	3
986	S:S:G228	S:S:Y227	4.35	No	Yes	2	8	7
987	S:S:F281	S:S:Y227	6.19	Yes	Yes	2	7	7
988	S:S:S308	S:S:Y227	6.36	Yes	Yes	2	8	7
989	S:S:D309	S:S:Y227	8.05	Yes	Yes	2	8	7
990	S:S:S310	S:S:Y227	8.9	Yes	Yes	2	6	7
991	S:S:F281	S:S:G228	3.01	Yes	No	2	7	8
992	S:S:E229	S:S:K252	13.5	No	No	0	6	5
993	S:S:F281	S:S:G231	4.52	Yes	No	0	7	7
994	S:S:F281	S:S:V232	3.93	Yes	No	0	7	5
995	S:S:E233	S:S:Q237	6.37	No	No	0	6	4
996	S:S:F235	S:S:I279	5.02	No	No	0	5	7
997	S:S:I247	S:S:T236	4.56	No	No	0	6	3
998	S:S:S239	S:S:V245	4.85	No	No	0	7	7
999	S:S:E241	S:S:I242	4.1	No	No	0	4	4
1000	S:S:G243	S:S:I242	3.53	No	No	0	8	4
1001	S:S:C246	S:S:V532	5.12	No	No	0	9	6
1002	S:S:C246	S:S:C534	7.28	No	No	0	9	9
1003	S:S:L269	S:S:Q249	2.66	No	No	0	6	6
1004	S:S:Q249	S:S:T272	5.67	No	Yes	0	6	3
1005	S:S:Q251	S:S:R268	18.69	No	Yes	0	5	4
1006	S:S:I253	S:S:P254	3.39	No	No	0	6	4
1007	S:S:D286	S:S:I253	7	No	No	0	4	6
1008	S:S:E261	S:S:P254	9.43	Yes	No	0	4	4
1009	S:S:E256	S:S:R255	9.3	No	No	0	3	3
1010	S:S:E261	S:S:P257	3.14	Yes	No	0	4	3
1011	S:S:F262	S:S:P257	4.33	No	No	0	3	3
1012	S:S:P259	S:S:R258	2.88	No	No	0	2	3
1013	S:S:E261	S:S:R258	3.49	Yes	No	0	4	3
1014	S:S:E261	S:S:I265	4.1	Yes	No	0	4	5
1015	S:S:F262	S:S:R289	19.24	No	No	0	3	2
1016	S:S:F262	S:S:I290	5.02	No	No	0	3	4
1017	S:S:E263	S:S:K267	2.7	No	No	20	3	3
1018	S:S:E263	S:S:K296	8.1	No	No	20	3	3
1019	S:S:E263	S:S:L297	5.3	No	Yes	20	3	3
1020	S:S:I265	S:S:I290	2.94	No	No	0	5	4
1021	S:S:I266	S:S:L297	2.85	No	Yes	0	4	3
1022	S:S:K267	S:S:L297	7.05	No	Yes	20	3	3
1023	S:S:F303	S:S:L269	4.87	Yes	No	0	7	6
1024	S:S:L270	S:S:Q299	11.98	No	No	3	3	4
1025	S:S:H302	S:S:L270	3.86	No	No	3	4	3
1026	S:S:A275	S:S:T272	3.36	No	Yes	14	7	3
1027	S:S:R276	S:S:S514	2.64	No	No	0	6	9
1028	S:S:A277	S:S:S514	3.42	No	No	2	8	9
1029	S:S:F303	S:S:V278	2.62	Yes	No	3	7	6
1030	S:S:V278	S:S:W305	4.9	No	Yes	3	6	7
1031	S:S:I279	S:S:I306	5.89	No	No	0	7	7
1032	S:S:A282	S:S:M280	3.22	No	Yes	0	5	5
1033	S:S:I287	S:S:M280	5.83	Yes	Yes	0	4	5
1034	S:S:M280	S:S:W305	3.49	Yes	Yes	0	5	7
1035	S:S:F281	S:S:S308	10.57	Yes	Yes	2	7	8
1036	S:S:E284	S:S:K314	9.45	No	No	0	3	5
1037	S:S:I287	S:S:L291	2.85	Yes	Yes	0	4	4
1038	S:S:I287	S:S:W311	11.74	Yes	Yes	0	4	6
1039	S:S:I287	S:S:P317	3.39	Yes	No	0	4	3
1040	S:S:L291	S:S:W305	5.69	Yes	Yes	3	4	7
1041	S:S:L291	S:S:Q321	5.32	Yes	Yes	3	4	3
1042	S:S:I324	S:S:L291	5.71	Yes	Yes	3	4	4
1043	S:S:E292	S:S:Q321	6.37	No	Yes	0	3	3
1044	S:S:A294	S:S:I324	3.25	No	Yes	0	4	4
1045	S:S:E323	S:S:K295	2.7	No	No	0	3	2
1046	S:S:K296	S:S:L297	2.82	No	Yes	20	3	3
1047	S:S:H302	S:S:Q299	4.95	No	No	3	4	4
1048	S:S:F303	S:S:Q299	3.51	Yes	No	3	7	4
1049	S:S:I324	S:S:S300	3.1	Yes	No	0	4	5
1050	S:S:F303	S:S:H302	7.92	Yes	No	3	7	4
1051	S:S:F303	S:S:W305	10.02	Yes	Yes	3	7	7
1052	S:S:L304	S:S:W504	5.69	No	Yes	2	7	7
1053	S:S:W305	S:S:W311	3.75	Yes	Yes	3	7	6
1054	S:S:A328	S:S:W305	3.89	No	Yes	3	7	7
1055	S:S:D309	S:S:S308	2.94	Yes	Yes	2	8	8
1056	S:S:S308	S:S:S310	3.26	Yes	Yes	2	8	6
1057	S:S:D309	S:S:S310	2.94	Yes	Yes	2	8	6
1058	S:S:A328	S:S:W311	3.89	No	Yes	3	7	6
1059	S:S:T330	S:S:W311	7.28	Yes	Yes	3	6	6
1060	S:S:W311	S:S:Y485	6.75	Yes	Yes	3	6	4
1061	S:S:G312	S:S:T330	3.64	No	Yes	0	5	6
1062	S:S:G312	S:S:L332	5.13	No	Yes	0	5	5
1063	S:S:L332	S:S:S313	3	Yes	No	3	5	4
1064	S:S:F474	S:S:S313	7.93	Yes	No	3	5	4
1065	S:S:S313	S:S:Y485	7.63	No	Yes	3	4	4
1066	S:S:K314	S:S:P317	3.35	No	No	0	5	3
1067	S:S:V318	S:S:Y476	3.79	No	Yes	0	4	5
1068	S:S:Q320	S:S:Y319	14.65	No	No	0	2	3
1069	S:S:I324	S:S:Q321	2.74	Yes	Yes	3	4	3
1070	S:S:E322	S:S:Y476	6.73	No	Yes	3	4	5
1071	S:S:E322	S:S:I478	2.73	No	Yes	3	4	2
1072	S:S:E326	S:S:I478	16.4	No	Yes	0	5	2
1073	S:S:G327	S:S:Q475	4.93	No	Yes	0	8	8
1074	S:S:Q475	S:S:V329	4.3	Yes	No	0	8	6
1075	S:S:F474	S:S:T330	3.89	Yes	Yes	3	5	6
1076	S:S:T330	S:S:Y485	3.75	Yes	Yes	3	6	4
1077	S:S:I331	S:S:Y471	3.63	Yes	Yes	2	6	8
1078	S:S:L332	S:S:P333	3.28	Yes	No	0	5	4
1079	S:S:F474	S:S:L332	8.53	Yes	Yes	3	5	5
1080	S:S:F404	S:S:P333	2.89	Yes	No	0	7	4
1081	S:S:P333	S:S:Y471	4.17	No	Yes	0	4	8
1082	S:S:K334	S:S:R470	12.38	No	No	0	5	4
1083	S:S:D472	S:S:K334	12.44	No	No	0	7	5
1084	S:S:H490	S:S:K334	2.62	No	No	0	2	5
1085	S:S:G400	S:S:R335	6	No	No	0	6	5
1086	S:S:Q398	S:S:S337	2.89	No	No	0	6	3
1087	S:S:I338	S:S:S454	3.1	No	Yes	0	6	4
1088	S:S:G340	S:S:R343	6	No	No	0	5	4
1089	S:S:F341	S:S:Q398	9.37	Yes	No	0	8	6
1090	S:S:F341	S:S:V402	7.87	Yes	No	38	8	6
1091	S:S:D342	S:S:Y396	6.9	No	Yes	0	4	5
1092	S:S:D342	S:S:Q398	14.36	No	No	0	4	6
1093	S:S:R348	S:S:Y344	18.52	Yes	Yes	0	5	7
1094	S:S:R355	S:S:Y344	3.09	Yes	Yes	0	4	7
1095	S:S:F345	S:S:F362	3.22	Yes	Yes	2	6	6
1096	S:S:F345	S:S:Y396	11.35	Yes	Yes	2	6	5
1097	S:S:A391	S:S:R346	6.91	No	No	2	3	4
1098	S:S:R346	S:S:Y396	3.09	No	Yes	2	4	5
1099	S:S:R348	S:S:S347	3.95	Yes	No	0	5	5
1100	S:S:N352	S:S:R348	7.23	No	Yes	0	3	5
1101	S:S:N353	S:S:R348	13.26	Yes	Yes	0	3	5
1102	S:S:N352	S:S:T349	7.31	No	No	0	3	5
1103	S:S:L350	S:S:W363	10.25	No	Yes	0	6	8
1104	S:S:N353	S:S:N356	4.09	Yes	Yes	2	3	8
1105	S:S:F359	S:S:N353	10.87	Yes	Yes	2	5	3
1106	S:S:F359	S:S:N356	6.04	Yes	Yes	2	5	8
1107	S:S:V357	S:S:W358	9.81	No	No	0	1	4
1108	S:S:F359	S:S:F362	5.36	Yes	Yes	2	5	6
1109	S:S:F359	S:S:W363	5.01	Yes	Yes	2	5	8
1110	S:S:E361	S:S:E365	3.81	No	No	6	5	2
1111	S:S:F362	S:S:N366	8.46	Yes	Yes	2	6	3
1112	S:S:F367	S:S:W363	19.04	Yes	Yes	2	7	8
1113	S:S:E388	S:S:W363	7.63	Yes	Yes	2	7	8
1114	S:S:E364	S:S:K370	4.05	No	No	0	6	4
1115	S:S:E364	S:S:L371	6.63	No	No	0	6	3
1116	S:S:F367	S:S:N366	8.46	Yes	Yes	2	7	3
1117	S:S:N366	S:S:S394	4.47	Yes	No	2	3	3
1118	S:S:E388	S:S:F367	7	Yes	Yes	2	7	7
1119	S:S:F367	S:S:S394	5.28	Yes	No	2	7	3
1120	S:S:C369	S:S:C384	7.28	No	No	0	8	9
1121	S:S:I381	S:S:K370	2.91	No	No	0	1	4
1122	S:S:C384	S:S:L371	7.94	No	No	0	9	3
1123	S:S:L387	S:S:T385	2.95	No	No	0	4	5
1124	S:S:E388	S:S:T385	7.06	Yes	No	0	7	5
1125	S:S:D393	S:S:E388	5.2	No	Yes	0	4	7
1126	S:S:R389	S:S:R392	12.79	No	No	0	4	2
1127	S:S:A391	S:S:Y396	4	No	Yes	2	3	5
1128	S:S:E399	S:S:K401	4.05	Yes	No	2	5	4
1129	S:S:I406	S:S:V402	3.07	No	No	0	8	6
1130	S:S:F404	S:S:Q403	4.68	Yes	Yes	0	7	7
1131	S:S:D407	S:S:Q403	6.53	Yes	Yes	39	8	7
1132	S:S:Q403	S:S:S454	2.89	Yes	Yes	39	7	4
1133	S:S:A455	S:S:Q403	4.55	No	Yes	0	4	7
1134	S:S:I406	S:S:S454	4.64	No	Yes	0	8	4
1135	S:S:D407	S:S:G453	5.03	Yes	No	0	8	6
1136	S:S:D407	S:S:S454	4.42	Yes	Yes	39	8	4
1137	S:S:D407	S:S:V459	4.38	Yes	No	0	8	6
1138	S:S:F451	S:S:S411	5.28	Yes	No	0	9	8
1139	S:S:F461	S:S:S411	3.96	Yes	No	0	8	8
1140	S:S:I446	S:S:M412	2.92	Yes	Yes	37	6	7
1141	S:S:F451	S:S:Y414	15.47	Yes	No	0	9	7
1142	S:S:A415	S:S:I446	3.25	No	Yes	0	8	6
1143	S:S:L416	S:S:L442	4.15	No	Yes	0	8	6
1144	S:S:H417	S:S:N418	3.83	No	No	0	7	4
1145	S:S:H417	S:S:K421	2.62	No	No	0	7	3
1146	S:S:L423	S:S:M419	2.83	Yes	Yes	8	4	5
1147	S:S:M419	S:S:M434	4.33	Yes	Yes	8	5	4
1148	S:S:E441	S:S:M419	4.06	Yes	Yes	8	6	5
1149	S:S:L442	S:S:M419	4.24	Yes	Yes	0	6	5
1150	S:S:M419	S:S:Y445	9.58	Yes	Yes	8	5	4
1151	S:S:C424	S:S:H420	4.42	Yes	No	8	6	3
1152	S:S:H420	S:S:M434	5.25	No	Yes	8	3	4
1153	S:S:D422	S:S:Y445	11.49	No	Yes	0	3	4
1154	S:S:L423	S:S:R433	4.86	Yes	No	0	4	3
1155	S:S:E441	S:S:L423	9.28	Yes	Yes	8	6	4
1156	S:S:L423	S:S:Y445	3.52	Yes	Yes	8	4	4
1157	S:S:C424	S:S:C431	7.28	Yes	No	0	6	6
1158	S:S:C424	S:S:M434	4.86	Yes	Yes	8	6	4
1159	S:S:C431	S:S:Y427	2.69	No	No	0	6	1
1160	S:S:L430	S:S:M434	8.48	No	Yes	0	3	4
1161	S:S:C431	S:S:P432	3.77	No	No	0	6	3
1162	S:S:I437	S:S:M434	2.92	No	Yes	0	3	4
1163	S:S:I437	S:S:L442	4.28	No	Yes	0	3	6
1164	S:S:D438	S:S:E441	6.5	No	Yes	0	4	6
1165	S:S:E441	S:S:Y445	6.73	Yes	Yes	8	6	4
1166	S:S:L443	S:S:R447	10.93	No	No	0	5	5
1167	S:S:G465	S:S:R447	6	No	No	19	7	5
1168	S:S:F451	S:S:V449	2.62	Yes	No	0	9	7
1169	S:S:F461	S:S:V449	2.62	Yes	No	0	8	7
1170	S:S:N450	S:S:T460	5.85	No	No	0	5	3
1171	S:S:F451	S:S:G453	3.01	Yes	No	0	9	6
1172	S:S:F451	S:S:V459	7.87	Yes	No	0	9	6
1173	S:S:N452	S:S:P458	3.26	No	No	0	5	3
1174	S:S:P468	S:S:T460	3.5	No	No	0	3	3
1175	S:S:F461	S:S:G465	3.01	Yes	No	19	8	7
1176	S:S:E463	S:S:N462	3.94	No	No	0	4	7
1177	S:S:E463	S:S:N464	9.2	No	No	0	4	6
1178	S:S:R470	S:S:T492	5.17	No	No	0	4	5
1179	S:S:W491	S:S:Y471	3.86	Yes	Yes	2	6	8
1180	S:S:I473	S:S:I488	4.42	No	No	0	8	8
1181	S:S:F474	S:S:Y485	5.16	Yes	Yes	3	5	4
1182	S:S:F474	S:S:V487	3.93	Yes	No	0	5	5
1183	S:S:Q475	S:S:Q477	8.96	Yes	No	0	8	6
1184	S:S:M502	S:S:Q475	6.8	Yes	Yes	2	7	8
1185	S:S:Q475	S:S:W504	7.67	Yes	Yes	2	8	7
1186	S:S:I478	S:S:Y476	3.63	Yes	Yes	3	2	5
1187	S:S:T483	S:S:Y476	9.99	No	Yes	3	4	5
1188	S:S:Y476	S:S:Y485	11.91	Yes	Yes	3	5	4
1189	S:S:K486	S:S:Q477	9.49	No	No	0	5	6
1190	S:S:Q477	S:S:Q503	8.96	No	No	0	6	3
1191	S:S:I478	S:S:T483	4.56	Yes	No	3	2	4
1192	S:S:Q503	S:S:T479	5.67	No	No	0	3	3
1193	S:S:E484	S:S:K486	6.75	No	No	0	2	5
1194	S:S:I488	S:S:L497	2.85	No	No	2	8	6
1195	S:S:I488	S:S:M502	2.92	No	Yes	2	8	7
1196	S:S:H490	S:S:T492	4.11	No	No	0	2	5
1197	S:S:H490	S:S:H496	14.33	No	No	0	2	3
1198	S:S:L495	S:S:W491	4.56	Yes	Yes	2	7	6
1199	S:S:L495	S:S:L497	5.54	Yes	No	2	7	6
1200	S:S:L497	S:S:M502	2.83	No	Yes	2	6	7
1201	S:S:E500	S:S:K498	4.05	No	No	40	4	5
1202	S:S:D501	S:S:K498	2.77	No	No	40	3	5
1203	S:S:D501	S:S:E500	3.9	No	No	40	3	4
1204	S:S:M502	S:S:W504	8.14	Yes	Yes	2	7	7
1205	S:S:P512	S:S:W504	17.57	No	Yes	0	8	7
1206	S:S:H511	S:S:P512	7.63	Yes	No	0	4	8
1207	S:S:C516	S:S:S517	3.44	No	No	0	9	9
1208	S:S:C516	S:S:C535	7.28	No	Yes	14	9	9
1209	S:S:S517	S:S:W536	13.59	No	No	0	9	7
1210	S:S:L518	S:S:P519	3.28	No	No	0	4	6
1211	S:S:C520	S:S:E524	7.6	No	No	41	9	7
1212	S:S:C520	S:S:W536	2.61	No	No	0	9	7
1213	S:S:C520	S:S:C538	7.28	No	No	41	9	9
1214	S:S:K521	S:S:P522	5.02	No	No	0	1	4
1215	S:S:E524	S:S:G523	3.27	No	No	0	7	9
1216	S:S:G523	S:S:Q547	6.58	No	No	0	9	3
1217	S:S:C538	S:S:E524	3.04	No	No	41	9	7
1218	S:S:E539	S:S:R525	3.49	No	No	0	4	6
1219	S:S:C553	S:S:R525	4.18	No	No	0	9	6
1220	S:S:K526	S:S:W536	16.24	No	No	0	8	7
1221	S:S:H537	S:S:V529	2.77	No	No	0	6	5
1222	S:S:R540	S:S:R566	11.73	No	No	0	3	6
1223	S:S:C541	S:S:C553	7.28	No	No	0	9	9
1224	S:S:E542	S:S:Y544	3.37	No	Yes	0	5	8
1225	S:S:E542	S:S:N545	14.46	No	No	0	5	7
1226	S:S:G543	S:S:R566	6	No	No	0	5	6
1227	S:S:L555	S:S:Y544	3.52	No	Yes	0	4	8
1228	S:S:R729	S:S:Y544	9.26	No	Yes	0	4	8
1229	S:S:L731	S:S:Y544	3.52	No	Yes	0	3	8
1230	S:S:P733	S:S:Y544	2.78	Yes	Yes	0	5	8
1231	S:S:C553	S:S:N545	3.15	No	No	0	9	7
1232	S:S:L555	S:S:N545	5.49	No	No	0	4	7
1233	S:S:V548	S:S:Y546	6.31	No	No	0	5	8
1234	S:S:E554	S:S:Y546	8.98	No	No	0	3	8
1235	S:S:C556	S:S:Y546	4.03	No	No	0	9	8
1236	S:S:E550	S:S:Q547	3.82	No	No	0	7	3
1237	S:S:Q547	S:S:T567	14.17	No	No	0	3	5
1238	S:S:D549	S:S:V548	2.92	No	No	42	8	5
1239	S:S:S552	S:S:V548	4.85	No	No	42	5	5
1240	S:S:D549	S:S:L551	9.5	No	No	0	8	3
1241	S:S:D549	S:S:S552	5.89	No	No	42	8	5
1242	S:S:L555	S:S:P557	9.85	No	No	0	4	4
1243	S:S:C556	S:S:C569	7.28	No	No	0	9	9
1244	S:S:P557	S:S:P562	9.74	No	No	0	4	8
1245	S:S:L558	S:S:Q560	6.65	No	Yes	0	4	5
1246	S:S:D559	S:S:Q560	3.92	No	Yes	0	5	5
1247	S:S:D559	S:S:Y725	6.9	No	Yes	0	5	4
1248	S:S:C569	S:S:Q560	3.05	No	Yes	0	9	5
1249	S:S:I572	S:S:Q560	4.12	No	Yes	0	8	5
1250	S:S:Q570	S:S:R561	7.01	No	Yes	0	5	6
1251	S:S:P573	S:S:R561	4.32	No	Yes	0	4	6
1252	S:S:P733	S:S:R561	5.76	Yes	Yes	0	5	6
1253	S:S:E734	S:S:R561	4.65	No	Yes	0	5	6
1254	S:S:P562	S:S:P733	7.79	No	Yes	0	8	5
1255	S:S:N563	S:S:N565	14.98	Yes	No	0	7	4
1256	S:S:G568	S:S:N563	3.39	No	Yes	0	2	7
1257	S:S:N563	S:S:Q570	5.28	Yes	No	0	7	5
1258	S:S:N565	S:S:T567	10.24	No	No	0	4	5
1259	S:S:I572	S:S:P573	3.39	No	No	0	8	4
1260	S:S:I572	S:S:Y725	13.3	No	Yes	0	8	4
1261	S:S:P573	S:S:R737	18.74	No	No	0	4	4
1262	S:S:I574	S:S:I723	2.94	No	No	0	5	4
1263	S:S:G738	S:S:I574	3.53	No	No	0	8	5
1264	S:S:I575	S:S:V739	4.61	No	No	0	6	6
1265	S:S:E578	S:S:K576	8.1	No	No	0	6	5
1266	S:S:I640	S:S:L577	2.85	No	No	0	8	8
1267	S:S:L577	S:S:P643	3.28	No	No	0	8	9
1268	S:S:L577	S:S:Y812	4.69	No	No	0	8	7
1269	S:S:E578	S:S:H580	3.69	No	No	0	6	3
1270	S:S:A642	S:S:E578	3.02	No	No	0	5	6
1271	S:S:V588	S:S:W579	3.68	No	No	0	4	6
1272	S:S:P582	S:S:S581	3.56	No	No	0	4	7
1273	S:S:S581	S:S:V585	4.85	No	No	0	7	6
1274	S:S:P582	S:S:W583	2.7	No	Yes	0	4	6
1275	S:S:W583	S:S:Y812	4.82	Yes	No	0	6	7
1276	S:S:T816	S:S:W583	3.64	No	Yes	0	8	6
1277	S:S:W583	X:X:?1	8.05	Yes	Yes	0	6	0
1278	S:S:A584	S:S:I640	3.25	No	No	0	7	8
1279	S:S:P587	S:S:V586	3.53	No	No	0	8	4
1280	S:S:P587	S:S:T819	6.99	No	No	0	8	7
1281	S:S:F637	S:S:V588	5.24	No	No	0	7	4
1282	S:S:A591	S:S:F637	4.16	No	No	0	7	7
1283	S:S:I592	S:S:I596	2.94	No	No	0	4	3
1284	S:S:G594	S:S:Y633	7.24	No	Yes	0	6	8
1285	S:S:F630	S:S:I595	5.02	No	No	0	4	6
1286	S:S:I595	S:S:Y633	3.63	No	Yes	0	6	8
1287	S:S:F630	S:S:T598	3.89	No	No	0	4	7
1288	S:S:T598	S:S:Y633	6.24	No	Yes	0	7	8
1289	S:S:L830	S:S:T598	4.42	Yes	No	0	8	7
1290	S:S:F600	S:S:T604	7.78	No	No	0	2	6
1291	S:S:F600	S:S:V838	3.93	No	No	0	2	7
1292	S:S:F605	S:S:V601	3.93	No	No	44	9	5
1293	S:S:V601	S:S:V838	4.81	No	No	44	5	7
1294	S:S:I602	S:S:V606	3.07	No	No	0	4	4
1295	S:S:I602	S:S:Y623	4.84	No	No	0	4	7
1296	S:S:I602	S:S:L626	4.28	No	No	0	4	9
1297	S:S:I841	S:S:T604	3.04	Yes	No	0	9	6
1298	S:S:I842	S:S:T604	6.08	No	No	0	6	6
1299	S:S:F605	S:S:Y834	5.16	No	Yes	0	9	9
1300	S:S:F605	S:S:V838	3.93	No	No	44	9	7
1301	S:S:R607	S:S:Y608	16.46	No	No	0	4	5
1302	S:S:T611	S:S:Y608	4.99	Yes	No	11	9	5
1303	S:S:I841	S:S:Y608	3.63	Yes	No	11	9	5
1304	S:S:P612	S:S:T611	3.5	No	Yes	11	8	9
1305	S:S:I613	S:S:T611	3.04	Yes	Yes	11	7	9
1306	S:S:T611	S:S:V614	4.76	Yes	No	0	9	9
1307	S:S:I841	S:S:T611	3.04	Yes	Yes	11	9	9
1308	S:S:N848	S:S:T611	7.31	No	Yes	11	9	9
1309	S:S:P612	S:S:R615	10.09	No	No	0	8	8
1310	S:S:N848	S:S:P612	11.4	No	No	11	9	8
1311	S:S:I613	S:S:K837	5.82	Yes	No	0	7	9
1312	S:S:I613	S:S:I841	2.94	Yes	Yes	11	7	9
1313	S:S:K837	S:S:S617	6.12	No	No	0	9	9
1314	S:S:E620	S:S:Q695	12.74	No	No	0	6	8
1315	S:S:T627	S:S:Y623	4.99	No	No	0	5	7
1316	S:S:T699	S:S:V624	3.17	Yes	No	0	7	7
1317	S:S:A665	S:S:L625	4.73	No	No	0	7	8
1318	S:S:L625	S:S:L666	5.54	No	No	0	8	7
1319	S:S:L626	S:S:L830	2.77	No	Yes	0	9	8
1320	S:S:L626	S:S:Y834	7.03	No	Yes	0	9	9
1321	S:S:F661	S:S:G628	4.52	No	No	0	7	8
1322	S:S:I629	S:S:Y633	4.84	No	Yes	0	8	8
1323	S:S:I629	S:S:S662	7.74	No	No	0	8	7
1324	S:S:I629	S:S:L830	9.99	No	Yes	0	8	8
1325	S:S:L631	S:S:S634	3	No	No	0	5	6
1326	S:S:L631	S:S:L657	4.15	No	No	0	5	7
1327	S:S:G658	S:S:L631	5.13	No	No	0	7	5
1328	S:S:C632	S:S:S662	5.16	Yes	No	0	6	7
1329	S:S:C632	S:S:M822	3.24	Yes	No	0	6	8
1330	S:S:A826	S:S:C632	3.61	No	Yes	0	8	6
1331	S:S:S827	S:S:Y633	6.36	No	Yes	0	6	8
1332	S:S:I635	S:S:L655	7.14	No	Yes	0	6	7
1333	S:S:I635	S:S:M822	2.92	No	No	0	6	8
1334	S:S:T636	S:S:T819	4.71	Yes	No	0	7	7
1335	S:S:M822	S:S:T636	3.01	No	Yes	0	8	7
1336	S:S:S823	S:S:T636	9.59	No	Yes	0	8	7
1337	S:S:I647	S:S:L638	4.28	No	No	0	6	5
1338	S:S:L638	S:S:R651	4.86	No	No	0	5	8
1339	S:S:M639	S:S:T815	3.01	No	No	0	8	8
1340	S:S:A642	S:S:D644	3.09	No	No	0	5	5
1341	S:S:L740	S:S:P643	8.21	No	No	0	6	9
1342	S:S:C742	S:S:P643	3.77	No	No	0	9	9
1343	S:S:D644	S:S:I647	2.8	No	No	0	5	6
1344	S:S:C648	S:S:R652	2.79	No	Yes	15	9	9
1345	S:S:C648	S:S:C742	7.28	No	No	15	9	9
1346	S:S:F650	S:S:S649	6.61	No	No	46	6	5
1347	S:S:P719	S:S:S649	8.91	Yes	No	46	8	5
1348	S:S:F650	S:S:P719	5.78	No	Yes	46	6	8
1349	S:S:R651	S:S:R652	5.33	No	Yes	0	8	9
1350	S:S:F654	S:S:R651	3.21	No	No	0	4	8
1351	S:S:L655	S:S:R652	6.07	Yes	Yes	15	7	9
1352	S:S:F714	S:S:R652	5.34	No	Yes	0	7	9
1353	S:S:C742	S:S:R652	2.79	No	Yes	15	9	9
1354	S:S:I744	S:S:R652	6.26	No	Yes	0	5	9
1355	S:S:L749	S:S:R652	3.64	No	Yes	15	7	9
1356	S:S:F654	S:S:V653	2.62	No	Yes	0	4	5
1357	S:S:V653	S:S:V710	3.21	Yes	No	47	5	6
1358	S:S:F714	S:S:V653	5.24	No	Yes	0	7	5
1359	S:S:L655	S:S:L749	2.77	Yes	No	15	7	7
1360	S:S:F661	S:S:L657	9.74	No	No	45	7	7
1361	S:S:I703	S:S:L657	2.85	No	No	45	7	7
1362	S:S:M659	S:S:Y663	5.99	No	Yes	0	8	7
1363	S:S:L753	S:S:M659	2.83	No	No	0	8	8
1364	S:S:M659	S:S:S756	10.73	No	No	0	8	7
1365	S:S:C660	S:S:Q706	6.1	No	No	48	7	9
1366	S:S:C660	S:S:S756	5.16	No	No	0	7	7
1367	S:S:C660	S:S:L759	3.17	No	Yes	48	7	9
1368	S:S:F661	S:S:I703	10.05	No	No	45	7	7
1369	S:S:S662	S:S:Y663	5.09	No	Yes	0	7	7
1370	S:S:M760	S:S:Y663	23.95	No	Yes	0	8	7
1371	S:S:S825	S:S:Y663	5.09	No	Yes	0	9	7
1372	S:S:A664	S:S:L759	4.73	No	Yes	0	9	9
1373	S:S:L666	S:S:T764	8.84	No	No	0	7	8
1374	S:S:Q695	S:S:T699	2.83	No	Yes	0	8	7
1375	S:S:F700	S:S:L696	4.87	No	No	0	2	6
1376	S:S:L702	S:S:L759	4.15	No	Yes	0	5	9
1377	S:S:L759	S:S:Q706	6.65	Yes	No	48	9	9
1378	S:S:G709	S:S:V712	3.68	No	No	0	7	4
1379	S:S:V710	S:S:W713	8.58	No	No	0	6	7
1380	S:S:F711	S:S:V715	7.87	No	No	0	3	2
1381	S:S:C751	S:S:W713	7.84	No	No	0	3	7
1382	S:S:H720	S:S:I721	2.65	No	No	0	4	5
1383	S:S:D743	S:S:H720	5.04	No	No	0	7	4
1384	S:S:I722	S:S:K741	8.72	No	No	0	3	6
1385	S:S:D743	S:S:I722	5.6	No	No	0	7	3
1386	S:S:I723	S:S:Y725	8.46	No	Yes	0	4	4
1387	S:S:D724	S:S:Q728	9.14	No	No	43	7	5
1388	S:S:D724	S:S:V739	4.38	No	No	43	7	6
1389	S:S:D724	S:S:K741	2.77	No	No	0	7	6
1390	S:S:G738	S:S:Y725	2.9	No	Yes	0	8	4
1391	S:S:E727	S:S:G726	3.27	No	No	0	5	2
1392	S:S:Q728	S:S:V739	2.87	No	No	43	5	6
1393	S:S:K735	S:S:T730	9.01	No	No	0	3	5
1394	S:S:A736	S:S:T730	3.36	No	No	0	4	5
1395	S:S:D732	S:S:P733	4.83	No	Yes	0	5	5
1396	S:S:D732	S:S:E734	14.29	No	No	0	5	5
1397	S:S:D732	S:S:K735	16.59	No	No	0	5	3
1398	S:S:K741	S:S:M811	10.08	No	No	0	6	5
1399	S:S:S745	S:S:S748	4.89	No	No	0	8	6
1400	S:S:D746	S:S:L747	5.43	No	No	0	3	3
1401	S:S:D746	S:S:K810	2.77	No	Yes	0	3	5
1402	S:S:I750	S:S:L747	2.85	Yes	No	0	5	3
1403	S:S:L749	S:S:L818	2.77	No	No	0	7	8
1404	S:S:I750	S:S:L753	2.85	Yes	No	0	5	8
1405	S:S:F801	S:S:I750	7.54	Yes	Yes	49	8	5
1406	S:S:F802	S:S:I750	3.77	No	Yes	49	6	5
1407	S:S:G754	S:S:I757	3.53	No	No	0	6	5
1408	S:S:C763	S:S:L759	3.17	No	Yes	0	8	9
1409	S:S:M760	S:S:T790	4.52	No	No	0	8	9
1410	S:S:M760	S:S:W794	4.65	No	No	0	8	9
1411	S:S:T762	S:S:V761	4.76	No	No	0	4	3
1412	S:S:M787	S:S:T764	7.53	No	No	0	9	8
1413	S:S:A780	S:S:F777	4.16	No	No	0	9	9
1414	S:S:E779	S:S:I783	2.73	No	No	0	9	9
1415	S:S:E779	S:S:L833	3.98	No	No	0	9	8
1416	S:S:K781	S:S:P782	5.02	No	No	0	9	5
1417	S:S:F785	S:S:K781	8.69	Yes	No	0	8	9
1418	S:S:G784	S:S:Y788	4.35	No	No	0	9	9
1419	S:S:F785	S:S:M832	3.73	Yes	No	0	8	6
1420	S:S:T786	S:S:T789	3.14	No	Yes	50	9	7
1421	S:S:S829	S:S:T786	3.2	No	No	0	7	9
1422	S:S:M832	S:S:T786	4.52	No	No	50	6	9
1423	S:S:T789	S:S:V828	4.76	Yes	No	0	7	8
1424	S:S:M832	S:S:T789	4.52	No	Yes	50	6	7
1425	S:S:S829	S:S:T790	3.2	No	No	0	7	9
1426	S:S:C791	S:S:L795	3.17	No	No	0	6	6
1427	S:S:I793	S:S:L824	4.28	No	No	0	8	7
1428	S:S:I793	S:S:S825	3.1	No	No	0	8	9
1429	S:S:I793	S:S:V828	4.61	No	No	0	8	8
1430	S:S:F797	S:S:W794	17.04	Yes	No	0	9	9
1431	S:S:S825	S:S:W794	8.65	No	No	0	9	9
1432	S:S:A796	W:W:?1	3.22	No	Yes	0	8	0
1433	S:S:F797	S:S:I800	3.77	Yes	Yes	0	9	8
1434	S:S:F797	S:S:F801	15	Yes	Yes	0	9	8
1435	S:S:F797	S:S:S821	6.61	Yes	No	0	9	8
1436	S:S:I798	S:S:P799	5.08	No	No	0	7	9
1437	S:S:P799	W:W:?1	15.12	No	Yes	9	9	0
1438	S:S:I800	S:S:T817	3.04	Yes	No	0	8	8
1439	S:S:I800	X:X:?1	15.14	Yes	Yes	9	8	0
1440	S:S:F801	S:S:F802	8.57	Yes	No	49	8	6
1441	S:S:F801	S:S:Q814	19.91	Yes	No	0	8	7
1442	S:S:F801	S:S:L818	9.74	Yes	No	0	8	8
1443	S:S:T804	W:W:?1	4.52	No	Yes	0	8	0
1444	S:S:A805	S:S:E809	3.02	No	Yes	0	6	8
1445	S:S:K810	S:S:Q806	14.92	Yes	No	0	5	7
1446	S:S:E809	S:S:S807	4.31	Yes	No	0	8	5
1447	S:S:E809	S:S:I813	2.73	Yes	No	0	8	5
1448	S:S:K810	S:S:M811	4.32	Yes	No	0	5	5
1449	S:S:K810	S:S:Q814	5.42	Yes	No	0	5	7
1450	S:S:I813	S:S:T817	3.04	No	No	0	5	8
1451	S:S:I813	X:X:?1	8.41	No	Yes	0	5	0
1452	S:S:Q814	S:S:T817	2.83	No	No	0	7	8
1453	S:S:V820	X:X:?1	10.54	No	Yes	0	7	0
1454	S:S:S821	X:X:?1	10.62	No	Yes	0	8	0
1455	S:S:G831	S:S:L830	3.42	No	Yes	0	1	8
1456	S:S:L833	S:S:Y834	15.24	No	Yes	0	8	9
1457	S:S:M835	S:S:P836	3.35	No	No	0	3	9
1458	S:S:F843	S:S:Y839	30.95	No	No	0	4	9
1459	S:S:F843	S:S:I842	6.28	No	No	0	4	6
1460	S:S:E846	S:S:H844	4.92	No	No	51	6	6
1461	S:S:H844	S:S:Q847	8.65	No	No	51	6	5
1462	S:S:E846	S:S:P845	4.72	No	No	0	6	8
1463	S:S:E846	S:S:Q847	14.02	No	No	51	6	5
1464	R:R:D285	R:R:E284	2.6	No	No	0	2	3
1465	S:S:D285	S:S:E284	2.6	No	No	0	2	3
1466	R:R:R108	R:R:T110	2.59	No	No	0	4	3
1467	R:R:F630	R:R:T599	2.59	No	No	0	4	3
1468	R:R:F777	R:R:T776	2.59	No	No	0	9	8
1469	S:S:R108	S:S:T110	2.59	No	No	0	4	3
1470	S:S:F630	S:S:T599	2.59	No	No	0	4	3
1471	S:S:F777	S:S:T776	2.59	No	No	0	9	8
1472	R:R:E399	R:R:E70	2.54	Yes	No	0	5	3
1473	R:R:E322	R:R:E323	2.54	No	No	0	4	3
1474	S:S:E399	S:S:E70	2.54	Yes	No	0	5	3
1475	S:S:E322	S:S:E323	2.54	No	No	0	4	3
1476	R:R:F303	R:R:I266	2.51	Yes	No	0	7	4
1477	R:R:F345	R:R:I390	2.51	Yes	No	0	6	6
1478	R:R:F367	R:R:I390	2.51	Yes	No	0	7	6
1479	S:S:F303	S:S:I266	2.51	Yes	No	0	7	4
1480	S:S:F345	S:S:I390	2.51	Yes	No	0	6	6
1481	S:S:F367	S:S:I390	2.51	Yes	No	0	7	6
1482	S:S:I575	S:S:R737	2.51	No	No	0	6	4
1483	R:R:K264	R:R:R268	2.48	No	Yes	0	3	4
1484	R:R:M639	R:R:R652	2.48	No	Yes	0	8	9
1485	S:S:K264	S:S:R268	2.48	No	Yes	0	3	4
1486	S:S:M639	S:S:R652	2.48	No	Yes	0	8	9
1487	R:R:L117	S:S:F169	2.44	No	Yes	0	5	6
1488	R:R:F169	R:R:L168	2.44	Yes	No	0	6	5
1489	R:R:F169	S:S:L117	2.44	Yes	No	0	6	5
1490	R:R:F589	R:R:L593	2.44	No	No	0	3	3
1491	S:S:F169	S:S:L168	2.44	Yes	No	0	6	5
1492	S:S:F589	S:S:L593	2.44	No	No	0	3	3
1493	R:R:D339	R:R:R343	2.38	No	No	0	5	4
1494	R:R:D393	R:R:R392	2.38	No	No	0	4	2
1495	R:R:D610	R:R:R615	2.38	No	No	0	5	8
1496	S:S:D339	S:S:R343	2.38	No	No	0	5	4
1497	S:S:D393	S:S:R392	2.38	No	No	0	4	2
1498	S:S:D610	S:S:R615	2.38	No	No	0	5	8
1499	R:R:I290	R:R:W305	2.35	No	Yes	0	4	7
1500	S:S:I290	S:S:W305	2.35	No	Yes	0	4	7
1501	R:R:Q237	R:R:R240	2.34	No	No	0	4	3
1502	R:R:Q321	R:R:R288	2.34	Yes	No	0	3	1
1503	R:R:L625	R:R:Y834	2.34	No	Yes	0	8	9
1504	S:S:Q237	S:S:R240	2.34	No	No	0	4	3
1505	S:S:Q321	S:S:R288	2.34	Yes	No	0	3	1
1506	S:S:L625	S:S:Y834	2.34	No	Yes	0	8	9
1507	R:R:E271	R:R:R268	2.33	No	Yes	0	4	4
1508	S:S:E271	S:S:R268	2.33	No	Yes	0	4	4
1509	R:R:G44	R:R:G99	2.11	No	No	0	9	9
1510	R:R:G49	R:R:G50	2.11	No	No	0	8	8
1511	R:R:G58	R:R:G65	2.11	No	No	0	2	3
1512	R:R:G243	R:R:G244	2.11	No	No	0	8	4
1513	S:S:G44	S:S:G99	2.11	No	No	0	9	9
1514	S:S:G49	S:S:G50	2.11	No	No	0	8	8
1515	S:S:G58	S:S:G65	2.11	No	No	0	2	3
1516	S:S:G243	S:S:G244	2.11	No	No	0	8	4
1517	R:R:F785	R:R:Y788	2.06	Yes	No	0	8	9
1518	S:S:F785	S:S:Y788	2.06	Yes	No	0	8	9
1519	R:R:G523	R:R:P522	2.03	No	No	0	9	4
1520	S:S:G523	S:S:P522	2.03	No	No	0	9	4
1521	R:R:C632	R:R:G658	1.96	Yes	No	0	6	7
1522	S:S:C632	S:S:G658	1.96	Yes	No	0	6	7
1523	R:R:P718	R:R:P719	1.95	No	Yes	0	7	8
1524	S:S:P718	S:S:P719	1.95	No	Yes	0	7	8
1525	R:R:C246	R:R:P533	1.88	No	No	0	9	3
1526	R:R:C424	R:R:P425	1.88	Yes	No	0	6	3
1527	S:S:C246	S:S:P533	1.88	No	No	0	9	3
1528	S:S:C424	S:S:P425	1.88	Yes	No	0	6	3
1529	R:R:A122	R:R:P144	1.87	No	No	0	3	3
1530	R:R:A316	R:R:P317	1.87	No	No	0	1	3
1531	R:R:A467	R:R:P468	1.87	No	No	0	4	3
1532	S:S:A122	S:S:P144	1.87	No	No	0	3	3
1533	S:S:A316	S:S:P317	1.87	No	No	0	1	3
1534	S:S:A467	S:S:P468	1.87	No	No	0	4	3
1535	R:R:G656	R:R:S752	1.86	No	No	0	6	7
1536	S:S:G656	S:S:S752	1.86	No	No	0	6	7
1537	R:R:G58	R:R:V62	1.84	No	No	0	2	1
1538	S:S:G58	S:S:V62	1.84	No	No	0	2	1
1539	R:R:G386	R:R:T385	1.82	No	No	0	3	5
1540	R:R:C534	R:R:C535	1.82	No	Yes	0	9	9
1541	R:R:G803	R:R:T804	1.82	No	No	0	8	8
1542	S:S:G386	S:S:T385	1.82	No	No	0	3	5
1543	S:S:C534	S:S:C535	1.82	No	Yes	0	9	9
1544	S:S:G803	S:S:T804	1.82	No	No	0	8	8
1545	R:R:A203	R:R:A234	1.79	No	No	0	6	4
1546	R:R:A336	R:R:A455	1.79	No	No	0	4	4
1547	S:S:A203	S:S:A234	1.79	No	No	0	6	4
1548	S:S:A336	S:S:A455	1.79	No	No	0	4	4
1549	R:R:P181	R:R:S230	1.78	No	No	0	5	4
1550	S:S:P181	S:S:S230	1.78	No	No	0	5	4
1551	R:R:G99	R:R:I47	1.76	No	No	0	9	5
1552	R:R:G49	R:R:I147	1.76	No	No	0	8	5
1553	R:R:G429	R:R:I96	1.76	No	No	0	3	5
1554	R:R:G149	R:R:I147	1.76	No	No	0	8	5
1555	R:R:G489	R:R:I473	1.76	No	No	0	9	8
1556	S:S:G99	S:S:I47	1.76	No	No	0	9	5
1557	S:S:G49	S:S:I147	1.76	No	No	0	8	5
1558	S:S:G429	S:S:I96	1.76	No	No	0	3	5
1559	S:S:G149	S:S:I147	1.76	No	No	0	8	5
1560	S:S:G489	S:S:I473	1.76	No	No	0	9	8
1561	R:R:P273	R:R:T272	1.75	No	Yes	0	7	3
1562	R:R:P458	R:R:T457	1.75	No	No	0	3	5
1563	S:S:P273	S:S:T272	1.75	No	Yes	0	7	3
1564	S:S:P458	S:S:T457	1.75	No	No	0	3	5
1565	R:R:G72	R:R:K71	1.74	No	Yes	0	5	5
1566	R:R:G439	R:R:K170	1.74	No	No	0	6	4
1567	R:R:G531	R:R:K530	1.74	No	No	0	6	6
1568	S:S:G72	S:S:K71	1.74	No	Yes	0	5	5
1569	S:S:G439	S:S:K170	1.74	No	No	0	6	4
1570	R:R:G444	R:R:L443	1.71	No	No	0	4	5
1571	R:R:C535	R:R:V529	1.71	Yes	No	0	9	5
1572	R:R:G594	R:R:L593	1.71	No	No	0	6	3
1573	R:R:G618	R:R:L621	1.71	No	No	0	9	8
1574	R:R:G656	R:R:L655	1.71	No	Yes	0	6	7
1575	R:R:G709	R:R:L708	1.71	No	No	0	7	3
1576	R:R:G754	R:R:L753	1.71	No	No	0	6	8
1577	S:S:G444	S:S:L443	1.71	No	No	0	4	5
1578	S:S:C535	S:S:V529	1.71	Yes	No	0	9	5
1579	S:S:G594	S:S:L593	1.71	No	No	0	6	3
1580	S:S:G618	S:S:L621	1.71	No	No	0	9	8
1581	S:S:G656	S:S:L655	1.71	No	Yes	0	6	7
1582	S:S:G709	S:S:L708	1.71	No	No	0	7	3
1583	S:S:G754	S:S:L753	1.71	No	No	0	6	8
1584	R:R:A325	R:R:V318	1.7	No	No	0	5	4
1585	R:R:A665	R:R:V624	1.7	No	No	0	7	7
1586	S:S:A325	S:S:V318	1.7	No	No	0	5	4
1587	S:S:A665	S:S:V624	1.7	No	No	0	7	7
1588	R:R:I744	R:R:P719	1.69	No	Yes	0	5	8
1589	S:S:I744	S:S:P719	1.69	No	Yes	0	5	8
1590	R:R:D43	R:R:G44	1.68	No	No	0	3	9
1591	R:R:A351	R:R:T349	1.68	No	No	0	5	5
1592	R:R:A455	R:R:T457	1.68	No	No	0	4	5
1593	R:R:A591	R:R:T636	1.68	No	Yes	0	7	7
1594	S:S:D43	S:S:G44	1.68	No	No	0	3	9
1595	S:S:A351	S:S:T349	1.68	No	No	0	5	5
1596	S:S:A455	S:S:T457	1.68	No	No	0	4	5
1597	S:S:A591	S:S:T636	1.68	No	Yes	0	7	7
1598	R:R:E271	S:S:G531	1.64	No	No	0	4	6
1599	R:R:E399	R:R:G400	1.64	Yes	No	0	5	6
1600	R:R:G531	S:S:E271	1.64	No	No	0	6	4
1601	R:R:E542	R:R:G543	1.64	No	No	0	5	5
1602	S:S:E399	S:S:G400	1.64	Yes	No	0	5	6
1603	S:S:E542	S:S:G543	1.64	No	No	0	5	5
1604	R:R:N274	R:R:P273	1.63	No	No	0	5	7
1605	S:S:N274	S:S:P273	1.63	No	No	0	5	7
1606	R:R:A203	R:R:I238	1.62	No	Yes	0	6	5
1607	R:R:A293	R:R:I266	1.62	No	No	0	5	4
1608	R:R:C369	R:R:K382	1.62	No	No	0	8	3
1609	R:R:A616	R:R:I613	1.62	No	Yes	0	9	7
1610	R:R:A641	R:R:I647	1.62	No	No	0	8	6
1611	R:R:S701	R:R:V697	1.62	No	No	0	3	3
1612	S:S:A203	S:S:I238	1.62	No	Yes	0	6	5
1613	S:S:A293	S:S:I266	1.62	No	No	0	5	4
1614	S:S:C369	S:S:K382	1.62	No	No	0	8	3
1615	S:S:A616	S:S:I613	1.62	No	Yes	0	9	7
1616	S:S:A641	S:S:I647	1.62	No	No	0	8	6
1617	S:S:S701	S:S:V697	1.62	No	No	0	3	3
1618	R:R:A222	R:R:K252	1.61	No	No	0	5	5
1619	R:R:D717	R:R:P718	1.61	No	No	0	6	7
1620	S:S:A222	S:S:K252	1.61	No	No	0	5	5
1621	S:S:D717	S:S:P718	1.61	No	No	0	6	7
1622	R:R:V210	R:R:V218	1.6	No	No	0	7	8
1623	R:R:S482	R:R:T479	1.6	No	No	0	4	3
1624	S:S:V210	S:S:V218	1.6	No	No	0	7	8
1625	S:S:S482	S:S:T479	1.6	No	No	0	4	3
1626	R:R:T599	R:R:V603	1.59	No	No	0	3	1
1627	S:S:T599	S:S:V603	1.59	No	No	0	3	1
1628	R:R:A212	R:R:L495	1.58	No	Yes	0	5	7
1629	S:S:A212	S:S:L495	1.58	No	Yes	0	5	7
1630	R:R:I703	R:R:S704	1.55	No	No	0	7	4
1631	R:R:I744	R:R:S748	1.55	No	No	0	5	6
1632	S:S:I703	S:S:S704	1.55	No	No	0	7	4
1633	S:S:I744	S:S:S748	1.55	No	No	0	5	6
1634	R:R:I698	R:R:V697	1.54	No	No	0	7	3
1635	S:S:I698	S:S:V697	1.54	No	No	0	7	3
1636	R:R:M835	R:R:V601	1.52	No	No	0	3	5
1637	R:R:I646	R:R:T645	1.52	No	No	0	4	3
1638	R:R:I721	R:R:T645	1.52	No	No	0	5	3
1639	R:R:I698	R:R:T699	1.52	No	Yes	0	7	7
1640	R:R:T789	S:S:I792	1.52	Yes	No	0	7	8
1641	R:R:I792	S:S:T789	1.52	No	Yes	0	8	7
1642	S:S:I646	S:S:T645	1.52	No	No	0	4	3
1643	S:S:I721	S:S:T645	1.52	No	No	0	5	3
1644	S:S:I698	S:S:T699	1.52	No	Yes	0	7	7
1645	R:R:K735	R:R:T730	1.5	No	No	0	3	5
1646	R:R:L707	R:R:V653	1.49	No	Yes	32	5	5
1647	R:R:L708	R:R:V705	1.49	No	No	0	3	5
1648	R:R:L707	R:R:V710	1.49	No	No	32	5	6
1649	S:S:L707	S:S:V653	1.49	No	Yes	47	5	5
1650	S:S:L708	S:S:V705	1.49	No	No	0	3	5
1651	S:S:L707	S:S:V710	1.49	No	No	47	5	6
1652	R:R:N216	R:R:V245	1.48	No	No	0	7	7
1653	R:R:N609	R:R:V614	1.48	No	No	0	5	9
1654	S:S:N216	S:S:V245	1.48	No	No	0	7	7
1655	S:S:N609	S:S:V614	1.48	No	No	0	5	9
1656	R:R:I238	R:R:I242	1.47	Yes	No	0	5	4
1657	S:S:I238	S:S:I242	1.47	Yes	No	0	5	4
1658	R:R:N87	R:R:T97	1.46	No	No	0	9	7
1659	S:S:N87	S:S:T97	1.46	No	No	0	9	7
1660	R:R:G726	R:R:Y725	1.45	No	Yes	0	2	4
1661	S:S:G726	S:S:Y725	1.45	No	Yes	0	2	4
1662	R:R:P259	R:R:R258	1.44	No	No	0	2	3
1663	R:R:K370	R:R:K383	1.44	No	No	0	4	1
1664	S:S:K370	S:S:K383	1.44	No	No	0	4	1
1665	R:R:G307	R:R:W311	1.41	No	Yes	0	6	6
1666	R:R:G709	R:R:W713	1.41	No	No	0	7	7
1667	S:S:G307	S:S:W311	1.41	No	Yes	0	6	6
1668	S:S:G709	S:S:W713	1.41	No	No	0	7	7
1669	R:R:C369	R:R:F367	1.4	No	Yes	0	8	7
1670	S:S:C369	S:S:F367	1.4	No	Yes	0	8	7
1671	S:S:M564	S:S:N563	1.4	No	Yes	0	3	7
1672	R:R:D438	R:R:K440	1.38	No	No	0	4	5
1673	S:S:D438	S:S:K440	1.38	No	No	0	4	5
1674	R:R:H511	R:R:T510	1.37	Yes	No	0	4	4
1675	R:R:I840	R:R:Q847	1.37	No	No	0	8	5
1676	S:S:H511	S:S:T510	1.37	Yes	No	0	4	4
1677	S:S:I840	S:S:Q847	1.37	No	No	0	8	5
1678	R:R:D466	R:R:N464	1.35	Yes	No	0	8	6
1679	S:S:D466	S:S:N464	1.35	Yes	No	0	8	6
1680	R:R:E779	R:R:L621	1.33	No	No	0	9	8
1681	S:S:E779	S:S:L621	1.33	No	No	0	9	8
1682	R:R:F700	R:R:T699	1.3	No	Yes	0	2	7
1683	S:S:F700	S:S:T699	1.3	No	Yes	0	2	7
1684	R:R:S622	R:R:Y834	1.27	No	Yes	0	8	9
1685	S:S:S622	S:S:Y834	1.27	No	Yes	0	8	9
1686	R:R:F637	R:R:I592	1.26	No	No	0	7	4
1687	S:S:F637	S:S:I592	1.26	No	No	0	7	4
1688	R:R:I315	R:R:Y485	1.21	No	Yes	0	2	4
1689	R:R:N609	R:R:R619	1.21	No	No	0	5	8
1690	S:S:I315	S:S:Y485	1.21	No	Yes	0	2	4
1691	S:S:N609	S:S:R619	1.21	No	No	0	5	8
1692	R:R:D185	R:R:R188	1.19	No	No	0	7	6
1693	R:R:D472	R:R:F474	1.19	No	Yes	0	7	5
1694	S:S:D185	S:S:R188	1.19	No	No	0	7	6
1695	S:S:D472	S:S:F474	1.19	No	Yes	0	7	5
1696	R:R:Q706	R:R:Y755	1.13	No	No	0	9	9
1697	R:R:F843	R:R:H844	1.13	No	No	0	4	6
1698	S:S:Q706	S:S:Y755	1.13	No	No	0	9	9
1699	S:S:F843	S:S:H844	1.13	No	No	0	4	6
1700	R:R:R288	R:R:Y319	1.03	No	No	0	1	3
1701	S:S:R288	S:S:Y319	1.03	No	No	0	1	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	7.48429	7	1	0
2	M:M:?1	6.945	8	2	0
3	R:R:F52	5.185	4	1	9
4	R:R:H55	5.06667	6	5	8
5	R:R:K71	5.2	5	1	5
6	R:R:R75	8.028	5	1	4
7	R:R:E77	6.2	5	1	8
8	R:R:M79	4.298	5	1	8
9	R:R:Y81	7.97	4	0	7
10	R:R:L98	3.175	4	0	9
11	R:R:V100	4.6325	4	1	7
12	R:R:I102	4.445	4	1	8
13	R:R:L103	5.832	5	5	5
14	R:R:C106	5.4375	4	5	7
15	R:R:Y111	5.075	4	5	3
16	R:R:L113	4.5925	4	0	5
17	R:R:S159	3.746	5	1	8
18	R:R:I160	5.35	4	1	5
19	R:R:V162	4.5075	4	1	5
20	R:R:L166	4.296	5	1	6
21	R:R:F169	6.6525	4	0	6
22	R:R:P172	4.06	4	0	9
23	R:R:Q173	5.27	6	1	8
24	R:R:Y176	5.718	5	1	7
25	R:R:T179	6.105	4	1	7
26	R:R:L183	9.2175	4	1	8
27	R:R:Y189	7.434	5	1	6
28	R:R:F192	7.714	5	1	8
29	R:R:R194	6.22667	6	1	9
30	R:R:V196	4.2975	4	0	7
31	R:R:P198	6.4975	4	1	7
32	R:R:D199	6.595	4	0	8
33	R:R:Y201	4.1875	4	1	4
34	R:R:Q202	4.175	6	1	9
35	R:R:Q204	4.5275	4	1	3
36	R:R:L213	5.725	4	1	7
37	R:R:W215	4.82857	7	1	9
38	R:R:Y217	6.902	5	12	9
39	R:R:L221	3.535	4	0	5
40	R:R:Y227	7.71571	7	1	7
41	R:R:I238	3.3375	4	1	5
42	R:R:R268	7.74	4	0	4
43	R:R:T272	3.9425	4	12	3
44	R:R:M280	4.195	4	0	5
45	R:R:F281	5.42143	7	1	7
46	R:R:I287	5.9525	4	0	4
47	R:R:L291	4.8925	4	4	4
48	R:R:L297	4.505	4	17	3
49	R:R:F303	5.24167	6	4	7
50	R:R:W305	4.87	7	4	7
51	R:R:S308	5.492	5	1	8
52	R:R:D309	4.365	6	1	8
53	R:R:W311	5.80333	6	4	6
54	R:R:Q321	4.1925	4	4	3
55	R:R:I324	3.7	4	4	4
56	R:R:T330	4.64	4	4	6
57	R:R:I331	3.0575	4	1	6
58	R:R:F341	6.3825	4	22	8
59	R:R:Y344	9.07	4	0	7
60	R:R:F345	5.94	5	1	6
61	R:R:R348	10.74	4	0	5
62	R:R:N353	8.6975	4	1	3
63	R:R:R355	7.455	4	0	4
64	R:R:N356	5.278	5	1	8
65	R:R:F359	6.82	4	1	5
66	R:R:F362	6.654	5	1	6
67	R:R:W363	10.4825	4	1	8
68	R:R:N366	6.3975	4	1	3
69	R:R:F367	7.28167	6	1	7
70	R:R:E388	6.7225	4	1	7
71	R:R:Y396	6.156	5	1	5
72	R:R:E399	5.5475	4	1	5
73	R:R:Q403	4.6625	4	23	7
74	R:R:F404	4.515	4	0	7
75	R:R:D407	5.09	4	23	8
76	R:R:M412	4.485	4	21	7
77	R:R:M419	5.008	5	7	5
78	R:R:L423	5.73	4	7	4
79	R:R:C424	4.61	4	7	6
80	R:R:M434	5.168	5	7	4
81	R:R:E441	6.6425	4	7	6
82	R:R:L442	4.81	4	0	6
83	R:R:Y445	7.83	4	7	4
84	R:R:I446	3.125	4	21	6
85	R:R:F451	6.85	5	0	9
86	R:R:S454	3.7625	4	23	4
87	R:R:F461	2.97	5	16	8
88	R:R:D466	7.9375	4	1	8
89	R:R:Y471	4.596	5	1	8
90	R:R:F474	5.105	6	4	5
91	R:R:Q475	6.532	5	1	8
92	R:R:Y476	7.21	5	4	5
93	R:R:I478	6.83	4	4	2
94	R:R:Y485	6.06833	6	4	4
95	R:R:W491	5.225	6	1	6
96	R:R:L495	3.448	5	1	7
97	R:R:M502	4.986	5	1	7
98	R:R:W504	8.752	5	1	7
99	R:R:H511	5.235	4	1	4
100	R:R:C535	4.0475	4	12	9
101	R:R:Y544	5.4275	4	26	8
102	R:R:Q560	4.435	4	0	5
103	R:R:R561	6.0175	4	18	6
104	R:R:N563	6.965	4	0	7
105	R:R:W583	5.12	4	0	6
106	R:R:T611	4.44	6	10	9
107	R:R:I613	3.355	4	10	7
108	R:R:C632	3.4925	4	0	6
109	R:R:Y633	5.662	5	0	8
110	R:R:T636	4.7475	4	0	7
111	R:R:R652	4.3375	8	13	9
112	R:R:V653	3.14	4	32	5
113	R:R:L655	4.4225	4	13	7
114	R:R:Y663	10.03	4	0	7
115	R:R:T699	2.205	4	0	7
116	R:R:P719	4.5825	4	31	8
117	R:R:Y725	6.602	5	0	4
118	R:R:P733	5.775	4	18	5
119	R:R:I750	4.2525	4	34	5
120	R:R:L759	4.374	5	33	9
121	R:R:F785	4.6925	4	0	8
122	R:R:T789	3.485	4	35	7
123	R:R:F797	10.605	4	0	9
124	R:R:I800	7.06	5	9	8
125	R:R:F801	12.152	5	34	8
126	R:R:E809	4.28	4	0	8
127	R:R:K810	6.8575	4	0	5
128	R:R:L830	5.15	4	0	8
129	R:R:Y834	6.208	5	0	9
130	R:R:I841	3.1625	4	10	9
131	S:S:F52	5.185	4	2	9
132	S:S:H55	5.06667	6	6	8
133	S:S:K71	5.2	5	2	5
134	S:S:R75	8.028	5	2	4
135	S:S:E77	6.2	5	2	8
136	S:S:M79	4.298	5	2	8
137	S:S:Y81	7.97	4	0	7
138	S:S:L98	3.175	4	0	9
139	S:S:V100	4.6325	4	2	7
140	S:S:I102	4.445	4	2	8
141	S:S:L103	5.832	5	6	5
142	S:S:C106	5.4375	4	6	7
143	S:S:Y111	5.075	4	6	3
144	S:S:S159	3.746	5	2	8
145	S:S:I160	5.35	4	2	5
146	S:S:V162	4.5075	4	2	5
147	S:S:L166	4.296	5	2	6
148	S:S:F169	6.6525	4	0	6
149	S:S:P172	4.06	4	0	9
150	S:S:Q173	5.27	6	2	8
151	S:S:Y176	5.718	5	2	7
152	S:S:T179	5.8475	4	2	7
153	S:S:L183	9.2175	4	2	8
154	S:S:Y189	7.434	5	2	6
155	S:S:F192	7.714	5	2	8
156	S:S:R194	6.22667	6	2	9
157	S:S:V196	4.2975	4	0	7
158	S:S:P198	6.4975	4	2	7
159	S:S:D199	6.595	4	0	8
160	S:S:Y201	4.1875	4	2	4
161	S:S:Q202	4.175	6	2	9
162	S:S:Q204	4.5275	4	2	3
163	S:S:L213	5.725	4	2	7
164	S:S:W215	4.82857	7	2	9
165	S:S:Y217	6.902	5	14	9
166	S:S:L221	3.535	4	0	5
167	S:S:Y227	7.71571	7	2	7
168	S:S:I238	3.3375	4	2	5
169	S:S:E261	5.04	4	0	4
170	S:S:R268	7.74	4	0	4
171	S:S:T272	3.9425	4	14	3
172	S:S:M280	4.195	4	0	5
173	S:S:F281	5.42143	7	2	7
174	S:S:I287	5.9525	4	0	4
175	S:S:L291	4.8925	4	3	4
176	S:S:L297	4.505	4	20	3
177	S:S:F303	5.24167	6	3	7
178	S:S:W305	4.87	7	3	7
179	S:S:S308	5.492	5	2	8
180	S:S:D309	4.365	6	2	8
181	S:S:S310	4.825	4	2	6
182	S:S:W311	5.80333	6	3	6
183	S:S:Q321	4.1925	4	3	3
184	S:S:I324	3.7	4	3	4
185	S:S:T330	4.64	4	3	6
186	S:S:I331	3.0575	4	2	6
187	S:S:L332	4.985	4	3	5
188	S:S:F341	6.3825	4	38	8
189	S:S:Y344	9.07	4	0	7
190	S:S:F345	5.94	5	2	6
191	S:S:R348	10.74	4	0	5
192	S:S:N353	8.6975	4	2	3
193	S:S:R355	7.455	4	0	4
194	S:S:N356	5.278	5	2	8
195	S:S:F359	6.82	4	2	5
196	S:S:F362	6.654	5	2	6
197	S:S:W363	10.4825	4	2	8
198	S:S:N366	6.3975	4	2	3
199	S:S:F367	7.28167	6	2	7
200	S:S:E388	6.7225	4	2	7
201	S:S:Y396	6.156	5	2	5
202	S:S:E399	5.5475	4	2	5
203	S:S:Q403	4.6625	4	39	7
204	S:S:F404	4.515	4	0	7
205	S:S:D407	5.09	4	39	8
206	S:S:M412	4.485	4	37	7
207	S:S:M419	5.008	5	8	5
208	S:S:L423	5.1225	4	8	4
209	S:S:C424	4.61	4	8	6
210	S:S:M434	5.168	5	8	4
211	S:S:E441	6.6425	4	8	6
212	S:S:L442	4.81	4	0	6
213	S:S:Y445	7.83	4	8	4
214	S:S:I446	3.125	4	37	6
215	S:S:F451	6.85	5	0	9
216	S:S:S454	3.7625	4	39	4
217	S:S:F461	2.97	5	19	8
218	S:S:D466	7.9375	4	2	8
219	S:S:Y471	4.596	5	2	8
220	S:S:F474	5.105	6	3	5
221	S:S:Q475	6.532	5	2	8
222	S:S:Y476	7.21	5	3	5
223	S:S:I478	6.83	4	3	2
224	S:S:Y485	6.06833	6	3	4
225	S:S:W491	5.225	6	2	6
226	S:S:L495	3.448	5	2	7
227	S:S:M502	4.986	5	2	7
228	S:S:W504	8.752	5	2	7
229	S:S:H511	5.235	4	2	4
230	S:S:C535	4.0475	4	14	9
231	S:S:Y544	4.49	5	0	8
232	S:S:Q560	4.435	4	0	5
233	S:S:R561	5.435	4	0	6
234	S:S:N563	6.2625	4	0	7
235	S:S:W583	4.8025	4	0	6
236	S:S:T611	4.44	6	11	9
237	S:S:I613	3.355	4	11	7
238	S:S:C632	3.4925	4	0	6
239	S:S:Y633	5.662	5	0	8
240	S:S:T636	4.7475	4	0	7
241	S:S:R652	4.3375	8	15	9
242	S:S:V653	3.14	4	47	5
243	S:S:L655	4.4225	4	15	7
244	S:S:Y663	10.03	4	0	7
245	S:S:T699	2.205	4	0	7
246	S:S:P719	4.5825	4	46	8
247	S:S:Y725	6.602	5	0	4
248	S:S:P733	5.29	4	0	5
249	S:S:I750	4.2525	4	49	5
250	S:S:L759	4.374	5	48	9
251	S:S:F785	4.6925	4	0	8
252	S:S:T789	3.485	4	50	7
253	S:S:F797	10.605	4	0	9
254	S:S:I800	6.29	5	9	8
255	S:S:F801	12.152	5	49	8
256	S:S:E809	5.3375	4	0	8
257	S:S:K810	6.8575	4	0	5
258	S:S:L830	5.15	4	0	8
259	S:S:Y834	6.208	5	0	9
260	S:S:I841	3.1625	4	11	9
261	W:W:?1	9.81375	8	9	0
262	X:X:?1	10.0029	7	9	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:T179	42.0067	8.24	Yes	Yes	1	0	7
2	R:R:T179	R:R:V196	54.3577	3.17	Yes	Yes	0	7	7
3	R:R:R194	R:R:V196	81.9697	2.62	Yes	Yes	0	9	7
4	R:R:L183	R:R:R194	48.5076	6.07	Yes	Yes	1	8	9
5	R:R:L183	R:R:Y189	48.5636	7.03	Yes	Yes	1	8	6
6	R:R:N164	R:R:Y189	48.7618	4.65	No	Yes	0	5	6
7	R:R:N164	S:S:M161	48.823	2.8	No	No	0	5	6
8	S:S:L113	S:S:M161	49.6005	9.9	No	No	0	5	6
9	S:S:I165	S:S:L113	50.1379	2.85	No	No	0	5	5
10	S:S:I165	S:S:S116	51.0226	6.19	No	No	0	5	5
11	S:S:S116	S:S:V162	24.2392	4.85	No	Yes	2	5	5
12	S:S:Q173	S:S:V162	22.8623	5.73	Yes	Yes	2	8	5
13	S:S:F192	S:S:Q173	46.5851	8.2	Yes	Yes	2	8	8
14	S:S:F192	S:S:R194	46.7514	4.28	Yes	Yes	2	8	9
15	S:S:R194	S:S:V196	100	2.62	Yes	Yes	0	9	7
16	S:S:T179	S:S:V196	84.6729	3.17	Yes	Yes	0	7	7
17	M:M:?1	S:S:T179	79.1427	7.21	Yes	Yes	2	0	7
18	S:S:L166	S:S:S116	26.8425	3	Yes	No	2	6	5
19	S:S:L166	S:S:Q173	23.9944	5.32	Yes	Yes	2	6	8
20	R:R:F192	R:R:R194	43.9893	4.28	Yes	Yes	1	8	9
21	R:R:F192	R:R:Q173	44.0921	8.2	Yes	Yes	1	8	8
22	R:R:Q173	R:R:V162	22.1808	5.73	Yes	Yes	1	8	5
23	R:R:S116	R:R:V162	26.4518	4.85	No	Yes	1	5	5
24	R:R:I165	R:R:S116	58.6514	6.19	No	No	0	5	5
25	R:R:I165	R:R:L113	58.6545	2.85	No	Yes	0	5	5
26	R:R:L113	R:R:M161	57.8356	9.9	Yes	No	0	5	6
27	R:R:M161	S:S:N164	57.4714	2.8	No	No	0	6	5
28	S:S:N164	S:S:Y189	57.4695	4.65	No	Yes	0	5	6
29	S:S:L183	S:S:Y189	57.6895	7.03	Yes	Yes	2	8	6
30	S:S:L183	S:S:R194	57.8005	6.07	Yes	Yes	2	8	9
31	R:R:L166	R:R:Q173	22.6159	5.32	Yes	Yes	1	6	8
32	R:R:L166	R:R:S116	32.1967	3	Yes	No	1	6	5
33	M:M:?1	S:S:K314	78.3611	3.94	Yes	No	0	0	5
34	L:L:?1	R:R:R75	11.0263	7.64	Yes	Yes	1	0	4
35	R:R:F359	R:R:N356	10.2155	6.04	Yes	Yes	1	5	8
36	L:L:?1	R:R:K314	29.1316	3.94	Yes	No	0	0	5
37	R:R:F404	R:R:V196	26.8904	7.87	Yes	Yes	0	7	7
38	R:R:K314	R:R:P317	28.7079	3.35	No	No	0	5	3
39	R:R:I287	R:R:P317	28.3953	3.39	Yes	No	0	4	3
40	R:R:I287	R:R:M280	18.8085	5.83	Yes	Yes	0	4	5
41	R:R:L221	R:R:M280	14.7999	4.24	Yes	Yes	0	5	5
42	R:R:L221	R:R:L269	13.0506	2.77	Yes	No	0	5	6
43	R:R:L269	R:R:Q249	13.7752	2.66	No	No	0	6	6
44	R:R:Q249	R:R:T272	13.4428	5.67	No	Yes	0	6	3
45	R:R:T272	R:R:Y217	12.7758	4.99	Yes	Yes	12	3	9
46	R:R:C516	R:R:Y217	11.2674	16.13	No	Yes	12	9	9
47	R:R:F281	R:R:V232	10.2965	3.93	Yes	No	0	7	5
48	R:R:W305	R:R:W311	16.1267	3.75	Yes	Yes	4	7	6
49	R:R:I290	R:R:W305	10.3672	2.35	No	Yes	0	4	7
50	S:S:K314	S:S:P317	78.3834	3.35	No	No	0	5	3
51	S:S:I287	S:S:P317	78.2763	3.39	Yes	No	0	4	3
52	S:S:I287	S:S:M280	73.5209	5.83	Yes	Yes	0	4	5
53	S:S:L221	S:S:M280	71.5952	4.24	Yes	Yes	0	5	5
54	R:R:F303	R:R:W305	11.2125	10.02	Yes	Yes	4	7	7
55	R:R:F404	R:R:P333	17.4532	2.89	Yes	No	0	7	4
56	R:R:L332	R:R:P333	17.8347	3.28	No	No	0	5	4
57	R:R:F474	R:R:L332	12.7477	8.53	Yes	No	0	5	5
58	R:R:C516	R:R:S517	11.111	3.44	No	No	0	9	9
59	R:R:S517	R:R:W536	10.9441	13.59	No	No	0	9	7
60	R:R:C520	R:R:W536	10.6102	2.61	No	No	0	9	7
61	R:R:C520	R:R:E524	10.2748	7.6	No	No	25	9	7
62	R:R:E524	R:R:G523	10.109	3.27	No	No	0	7	9
63	S:S:L221	S:S:L269	70.7393	2.77	Yes	No	0	5	6
64	S:S:L269	S:S:Q249	83.8971	2.66	No	No	0	6	6
65	S:S:Q249	S:S:T272	83.7636	5.67	No	Yes	0	6	3
66	S:S:T272	S:S:Y217	83.4746	4.99	Yes	Yes	14	3	9
67	S:S:C516	S:S:Y217	82.7436	16.13	No	Yes	14	9	9
68	S:S:C516	S:S:S517	82.8234	3.44	No	No	0	9	9
69	S:S:S517	S:S:W536	82.756	13.59	No	No	0	9	7
70	S:S:C520	S:S:W536	82.6208	2.61	No	No	0	9	7
71	S:S:C520	S:S:E524	82.4646	7.6	No	No	41	9	7
72	S:S:E524	S:S:G523	82.4178	3.27	No	No	0	7	9
73	S:S:G523	S:S:Q547	82.2144	6.58	No	No	0	9	3
74	S:S:Q547	S:S:T567	82.0786	14.17	No	No	0	3	5
75	S:S:N565	S:S:T567	82.0106	10.24	No	No	0	4	5
76	S:S:N563	S:S:N565	81.9426	14.98	Yes	No	0	7	4
77	S:S:N563	S:S:Q570	81.7382	5.28	Yes	No	0	7	5
78	S:S:Q570	S:S:R561	81.67	7.01	No	Yes	0	5	6
79	S:S:P573	S:S:R561	79.5333	4.32	No	Yes	0	4	6
80	S:S:P573	S:S:R737	78.0614	18.74	No	No	0	4	4
81	S:S:I575	S:S:R737	77.9908	2.51	No	No	0	6	4
82	S:S:I575	S:S:V739	77.9202	4.61	No	No	0	6	6
83	S:S:D724	S:S:V739	77.7594	4.38	No	No	43	7	6
84	S:S:D724	S:S:K741	77.708	2.77	No	No	0	7	6
85	S:S:K741	S:S:M811	77.2114	10.08	No	No	0	6	5
86	S:S:K810	S:S:M811	77.1403	4.32	Yes	No	0	5	5
87	S:S:K810	S:S:Q814	67.8809	5.42	Yes	No	0	5	7
88	S:S:Q814	S:S:T817	34.1885	2.83	No	No	0	7	8
89	S:S:I800	S:S:T817	32.5489	3.04	Yes	No	0	8	8
90	R:R:I800	S:S:I800	33.5779	4.42	Yes	Yes	9	8	8
91	R:R:F797	R:R:I800	29.3245	3.77	Yes	Yes	0	9	8
92	R:R:F797	R:R:W794	22.7727	17.04	Yes	No	0	9	9
93	R:R:M760	R:R:W794	11.2854	4.65	No	No	0	8	9
94	R:R:M760	R:R:Y663	10.8136	23.95	No	Yes	0	8	7
95	R:R:S662	R:R:Y663	19.7528	5.09	No	Yes	0	7	7
96	R:R:S825	R:R:W794	11.3933	8.65	No	No	0	9	9
97	R:R:S825	R:R:Y663	10.8394	5.09	No	Yes	0	9	7
98	R:R:I629	R:R:S662	15.2985	7.74	No	No	0	8	7
99	R:R:I629	R:R:L830	12.4895	9.99	No	Yes	0	8	8
100	R:R:L626	R:R:L830	11.2977	2.77	No	Yes	0	9	8
101	R:R:L626	R:R:Y834	10.2947	7.03	No	Yes	0	9	9
102	S:S:F801	S:S:Q814	33.6396	19.91	Yes	No	0	8	7
103	S:S:F797	S:S:F801	19.3864	15	Yes	Yes	0	9	8
104	S:S:F797	S:S:W794	20.5768	17.04	Yes	No	0	9	9
105	S:S:M760	S:S:W794	10.0973	4.65	No	No	0	8	9
106	S:S:S825	S:S:W794	10.3854	8.65	No	No	0	9	9
107	S:S:F404	S:S:V196	15.427	7.87	Yes	Yes	0	7	7
108	S:S:W305	S:S:W311	22.3834	3.75	Yes	Yes	3	7	6
109	S:S:F404	S:S:P333	17.8226	2.89	Yes	No	0	7	4
110	S:S:L332	S:S:P333	23.4825	3.28	Yes	No	0	5	4
111	S:S:T330	S:S:W311	10.6985	7.28	Yes	Yes	3	6	6
112	S:S:F474	S:S:L332	12.0278	8.53	Yes	Yes	3	5	5
113	S:S:W311	S:S:Y485	10.9716	6.75	Yes	Yes	3	6	4
114	S:S:F303	S:S:W305	18.6394	10.02	Yes	Yes	3	7	7
115	S:S:I750	S:S:L753	17.8439	2.85	Yes	No	0	5	8
116	S:S:L753	S:S:M659	17.283	2.83	No	No	0	8	8
117	S:S:M659	S:S:Y663	15.748	5.99	No	Yes	0	8	7
118	S:S:S662	S:S:Y663	32.5192	5.09	No	Yes	0	7	7
119	S:S:I629	S:S:S662	28.2412	7.74	No	No	0	8	7
120	S:S:I629	S:S:L830	22.9072	9.99	No	Yes	0	8	8
121	S:S:L626	S:S:L830	20.6327	2.77	No	Yes	0	9	8
122	S:S:L626	S:S:Y834	18.7278	7.03	No	Yes	0	9	9
123	S:S:F605	S:S:Y834	10.7148	5.16	No	Yes	0	9	9
124	S:S:F303	S:S:L269	13.2295	4.87	Yes	No	0	7	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:?1	S:S:K71	7.88	2	Yes	Yes	0	5	0	1
M:M:?1	S:S:R75	7.64	2	Yes	Yes	0	4	0	1
M:M:?1	S:S:S156	6.29	2	Yes	No	0	9	0	1
M:M:?1	S:S:T179	7.21	2	Yes	Yes	0	7	0	1
M:M:?1	S:S:Y227	15.56	2	Yes	Yes	0	7	0	1
M:M:?1	S:S:D309	2.84	2	Yes	Yes	0	8	0	1
M:M:?1	S:S:S310	4.2	2	Yes	Yes	0	6	0	1
M:M:?1	S:S:K314	3.94	2	Yes	No	0	5	0	1
S:S:K68	S:S:K71	8.62	0	No	Yes	5	5	2	1
S:S:K71	S:S:R75	3.71	2	Yes	Yes	5	4	1	1
S:S:E284	S:S:K71	4.05	0	No	Yes	3	5	2	1
S:S:R75	S:S:Y176	6.17	2	Yes	Yes	4	7	1	2
S:S:E399	S:S:R75	13.96	2	Yes	Yes	5	4	2	1
S:S:K401	S:S:R75	8.66	2	No	Yes	4	4	2	1
S:S:A180	S:S:S156	3.42	0	No	No	7	9	2	1
S:S:T179	S:S:V196	3.17	2	Yes	Yes	7	7	1	2
S:S:D199	S:S:T179	10.12	0	Yes	Yes	8	7	2	1
S:S:D309	S:S:T179	2.89	2	Yes	Yes	8	7	1	1
S:S:D199	S:S:Q202	5.22	0	Yes	Yes	8	9	2	2
S:S:D199	S:S:Y227	4.6	0	Yes	Yes	8	7	2	1
S:S:F281	S:S:Q202	3.51	2	Yes	Yes	7	9	2	2
S:S:Q202	S:S:S308	4.33	2	Yes	Yes	9	8	2	2
S:S:D309	S:S:Q202	6.53	2	Yes	Yes	8	9	1	2
S:S:G228	S:S:Y227	4.35	2	No	Yes	8	7	2	1
S:S:F281	S:S:Y227	6.19	2	Yes	Yes	7	7	2	1
S:S:S308	S:S:Y227	6.36	2	Yes	Yes	8	7	2	1
S:S:D309	S:S:Y227	8.05	2	Yes	Yes	8	7	1	1
S:S:S310	S:S:Y227	8.9	2	Yes	Yes	6	7	1	1
S:S:F281	S:S:G228	3.01	2	Yes	No	7	8	2	2
S:S:F281	S:S:S308	10.57	2	Yes	Yes	7	8	2	2
S:S:E284	S:S:K314	9.45	0	No	No	3	5	2	1
S:S:D309	S:S:S308	2.94	2	Yes	Yes	8	8	1	2
S:S:S308	S:S:S310	3.26	2	Yes	Yes	8	6	2	1
S:S:D309	S:S:S310	2.94	2	Yes	Yes	8	6	1	1
S:S:K314	S:S:P317	3.35	0	No	No	5	3	1	2
S:S:E399	S:S:K401	4.05	2	Yes	No	5	4	2	2
S:S:G72	S:S:K71	1.74	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
100.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
100.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
100.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
100.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
100.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626
100.00	Single	7DD5	Ca	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
100.00	Single	7DTT	Ca	7DTT-CaS; CaS-Ca-Ca
100.00	Single	7DTT	Ca	7DTT-CaS; CaS-Ca-Ca
100.00	Single	7DTU	Tryptophan	7DTU-CaS; CaS-Tryptophan
100.00	Single	7DTU	Tryptophan	7DTU-CaS; CaS-Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS; CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS; CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet	7M3F-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet	7M3F-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7SIL	Ca	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIL	Ca	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
100.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TQB	Ca; LY379268	8TQB-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TQB	Ca; LY379268	8TQB-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8WG9	PubChem 179394	8WG9-mGlu4; mGlu2-PubChem 179394
100.00	Single	8WGB	Glutamate	8WGB-mGlu4; mGlu2-Glutamate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGB	Glutamate	8WGB-mGlu4; mGlu2-Glutamate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGC	LY379268	8WGC-mGlu2; mGlu4-LY379268
100.00	Single	8WGD	LY341495; CPPG	8WGD-mGlu4; mGlu2-LY341495; CPPG
100.00	Single	8WGD	LY341495; CPPG	8WGD-mGlu4; mGlu2-LY341495; CPPG
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WVX	Norrin	8WVX-LGR4-Norrin
100.00	Single	8WVY	Norrin	8WVY-LGR4-Norrin
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU29
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU29
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
100.00	Single	9ASB	Ca	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AVG	Ca	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVL	Ca	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AXF	Ca	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AYF	Ca	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
100.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
100.00	Single	9C1P	Ca	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C2F	Ca	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2; Arrestin2
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2; Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9KB7	R-spondin-2	9KB7-LGR4-R-spondin-2
100.00	Single	9KGK	NB18	9KGK-LGR4-NB18
100.00	Single	9KHH	Norrin	9KHH-LGR4-Norrin
100.00	Single	9MBA	Glutamate	9MBA-mGlu8; mGlu8-Glutamate-Arrestin2 ; Arrestin2
100.00	Single	9MBA	Glutamate	9MBA-mGlu8; mGlu8-Glutamate-Arrestin2 ; Arrestin2
100.00	Single	9MBB	LY341495	9MBB-mGlu8; mGlu8-LY341495
100.00	Single	9MBB	LY341495	9MBB-mGlu8; mGlu8-LY341495
100.00	Single	9MBC	DCPG	9MBC-mGlu8; mGlu8-DCPG-AZ12216052
100.00	Single	9S37	NB21	9S37-LGR4-NB21
100.00	Single	9S38	NB21	9S38-LGR4-NB21
100.00	Single	9UTB	Sucralose	9UTB-TAS1R2; TAS1R3-Sucralose
50.00	Single	7DD6	Ca	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD7	Ca	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	9ASB	Ca	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9AVG	Ca	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AYF	Ca	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
50.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
33.33	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
33.33	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
25.00	Single	7UTZ	TSH	7UTZ-TSH-TSH-DPPC-Gs/β1/γ2
25.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
25.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
20.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
20.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
20.00	Single	8I2G	FSH	8I2G-FSH-FSH-PubChem 67530240-Gs/β1/γ2
20.00	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
16.67	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
16.67	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
14.29	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
14.29	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
14.29	Single	8JEF	PubChem 11367166	8JEF-HCA₃-PubChem 11367166-Gi1/β1/γ2
14.29	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
14.29	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
14.29	Single	9IJR	C17	9IJR-GPR52-C17-Arrestin2
14.29	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
12.50	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
12.50	Single	6LI0	C17	6LI0-GPR52-C17
12.50	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
12.50	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
12.50	Single	9B9Y	Taranabant	9B9Y-CB₁-Taranabant
12.50	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Single	9MNI	dC2_05	9MNI-CTLike-dC2_05-RAMP1
11.11	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
11.11	Single	4BWB	Neurotensin-(8-12)	4BWB-NTS₁-Neurotensin-(8-12)
11.11	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	6LFO	CXCL8	6LFO-CXCR2-CXCL8-Gi1/β1/γ2
11.11	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
11.11	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
11.11	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
11.11	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
11.11	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
11.11	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
11.11	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
11.11	Single	8YNF	CXCL8	8YNF-ACKR1-CXCL8
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Single	9KO2	CCL19	9KO2-CCR7-CCL19-Gi1/β1
11.11	Single	9KO6	CCL19	9KO6-CCR7-CCL19
11.11	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
11.11	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
11.11	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
11.11	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
10.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
10.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
10.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
10.00	Single	7UTZ	DPPC	7UTZ-TSH-TSH-DPPC-Gs/β1/γ2
10.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9BA0	MRI-1891	9BA0-CB₁-MRI-1891
10.00	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
10.00	Single	9M2F	Neuropeptide-FF	9M2F-NPFF1-Neuropeptide-FF-Gi1/β1/γ2
10.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
10.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-CXCL8-Gi1/β1/γ2
10.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
10.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
10.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.09	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.09	Single	5T04	Neurotensin-(8-13)	5T04-NTS₁-Neurotensin-(8-13)
9.09	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
9.09	Single	6D27	CAY10471	6D27-DP₂-CAY10471
9.09	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
9.09	Single	6Z4V	Neurotensin-(9-13)	6Z4V-NTS₁-Neurotensin-(9-13)
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
9.09	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
9.09	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
9.09	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
9.09	Single	7VIF	FTY720-P	7VIF-S1P₁-FTY720-P-Gi1/β1/γ2
9.09	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
9.09	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
9.09	Single	8IC0	CXCL8	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
9.09	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9MET	Gp120; CD4	9MET-CXCR4-Gp120; CD4
9.09	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
9.09	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
9.09	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
9.09	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
8.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
8.33	Single	5C1M	BU72	5C1M-μ-BU72
8.33	Single	6LFM	CXCL8	6LFM-CXCR2-CXCL8-Gi1/β1/γ2
8.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
8.33	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
8.33	Single	7C4S	S1P	7C4S-S1P₃-S1P
8.33	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
8.33	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
8.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
8.33	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
8.33	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZYT	Neurotensin-(8-13)	8ZYT-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
8.33	Single	9B9Z	MRI-1867	9B9Z-CB₁-MRI-1867
8.33	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
8.33	Single	9KO4	CCL21	9KO4-CCR7-CCL21-Gi1/β1/γ2
8.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-CXCL8-Gi1/β1/γ2
8.33	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
8.33	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
7.69	Single	3ZEV	Neurotensin-(7-13)	3ZEV-NTS₁-Neurotensin-(7-13)
7.69	Single	4BV0	Neurotensin-(7-13)	4BV0-NTS₁-Neurotensin-(7-13)
7.69	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
7.69	Single	5V56	TC114	5V56-SMO-TC114
7.69	Single	5V57	TC114	5V57-SMO-TC114
7.69	Single	6OS1	TRV026	6OS1-AT₁-TRV026
7.69	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
7.69	Single	7F1T	CCL3	7F1T-CCR5-CCL3
7.69	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
7.69	Single	7L0P	Neurotensin-(8-13)	7L0P-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.69	Single	7L0Q	Neurotensin-(8-13)	7L0Q-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.69	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
7.69	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
7.69	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
7.69	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
7.69	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
7.69	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	8FMZ	Neurotensin-(8-13)	8FMZ-NTS₁-Neurotensin-(8-13)-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8FN1	Neurotensin-(8-13)	8FN1-NTS₁-Neurotensin-(8-13)-chim(NtGi1-Go)/β1/γ2
7.69	Single	8HQC	C5a	8HQC-C5a₁-C5a-Go/β1/γ2
7.69	Single	8I2G	PubChem 67530240	8I2G-FSH-FSH-PubChem 67530240-Gs/β1/γ2
7.69	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
7.69	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
7.69	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8JZP	C5a	8JZP-C5a₁-C5a-Go/β1/γ2
7.69	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
7.69	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
7.69	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
7.69	Single	9IZG	LPA	9IZG-LPA₁-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	9JCL	ADP	9JCL-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
7.69	Single	9L16	CCL21	9L16-CCR7-CCL21
7.69	Single	9MEN	Gp120 (V3 loop)	9MEN-CXCR4-Gp120 (V3 loop)
7.69	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
7.69	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
7.69	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
7.69	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
7.69	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.69	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
7.69	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.14	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
7.14	Single	4XEE	Neurotensin-(8-13)	4XEE-NTS₁-Neurotensin-(8-13)
7.14	Single	4XES	Neurotensin-(8-13)	4XES-NTS₁-Neurotensin-(8-13)
7.14	Single	6OS0	Angiotensin II	6OS0-AT₁-Angiotensin II
7.14	Single	6OS2	TRV026	6OS2-AT₁-TRV026
7.14	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
7.14	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
7.14	Single	6YVR	Neurotensin-(6-13)	6YVR-NTS₁-Neurotensin-(6-13)
7.14	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
7.14	Single	7EW2	FTY720-P	7EW2-S1P₃-FTY720-P-Gi1/β1/γ2
7.14	Single	7L0S	Neurotensin-(8-13)	7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.14	Single	7W0N	Elabela	7W0N-Apelin; Apelin-Elabela-Gi1/β1/γ2
7.14	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
7.14	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8T3Q	Doconexent	8T3Q-FFA4-Doconexent-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	8U26	Substance-P	8U26-NK₁-Substance-P-Gs/β1/γ2
7.14	Single	8XQJ	JN241	8XQJ-Apelin; Apelin-JN241
7.14	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
7.14	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
7.14	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
7.14	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
7.14	Single	9ECJ	S-geranylgeranyl-L-glutathione	9ECJ-P2Y8-S-geranylgeranyl-L-glutathione-G13/β1/γ2
7.14	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
7.14	Single	9VIF	Neuropeptide-VF	9VIF-NPFF1-Neuropeptide-VF-Gi1/β1/γ2
7.14	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
7.14	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
7.14	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
7.14	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
7.14	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.14	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
7.14	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
7.14	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
7.14	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
7.14	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
7.14	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-C5-guano-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-DAMGO-Gi1/β1/γ2
7.14	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-C5-guano-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-DAMGO-Gi1/β1/γ2
7.14	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
7.14	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.14	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM-5541-Gi1/β1/γ2 7EW2-S1P₃-FTY720-P-Gi1/β1/γ2
6.67	Single	4BUO	Neurotensin-(8-13)	4BUO-NTS₁-Neurotensin-(8-13)
6.67	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
6.67	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
6.67	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
6.67	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
6.67	Single	6UP7	Neurotensin-(8-13)	6UP7-NTS₁-Neurotensin-(8-13)-Arrestin2
6.67	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
6.67	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
6.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
6.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
6.67	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
6.67	Single	8E0G	BU72	8E0G-μ-BU72
6.67	Single	8FN0	Neurotensin-(8-13)	8FN0-NTS₁-Neurotensin-(8-13)-SBI-553-chim(NtGi1-Go)/β1/γ2
6.67	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
6.67	Single	8JPF	Neurotensin-(8-13)	8JPF-NTS₁-Neurotensin-(8-13)-SBI-553
6.67	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
6.67	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
6.67	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
6.67	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
6.67	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
6.67	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9IZF	LPA	9IZF-LPA₁-LPA-Gi1/β1/γ2
6.67	Single	9KWX	C5a-des-Arg	9KWX-C5a₁-C5a-des-Arg-Go/β1/γ2
6.67	Single	9UYM	Chemerin-9	9UYM-CML2-Chemerin-9-chim(Arrestin3-CtArrestin2)
6.67	Single	9WP9	S1P	9WP9-S1P₃-S1P-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
6.67	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM-5541-Gi1/β1/γ2 7EW2-S1P₃-FTY720-P-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
6.67	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	5VBL	AMG3054	5VBL-Apelin-AMG3054
6.25	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
6.25	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
6.25	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
6.25	Single	7RKF	CX3CL1	7RKF-US28-CX3CL1-GDP-chim(NtGi1-G11)/β1/γ2
6.25	Single	7RKN	CX3CL1	7RKN-US28-CX3CL1-Gi1/β1/γ2
6.25	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
6.25	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
6.25	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
6.25	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
6.25	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs/β1/γ2
6.25	Single	8XQJ	JN241	8XQJ-Apelin; Apelin-JN241
6.25	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
6.25	Single	9KX6	C5a-des-Arg	9KX6-C5a₁-C5a-des-Arg-Go/β1/γ2
6.25	Single	9UMJ	EP54	9UMJ-C3a_B-EP54-Go/β1/γ2
6.25	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
6.25	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
6.25	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
6.25	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
6.25	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
5.88	Single	4XT1	CX3CL1	4XT1-US28-CX3CL1
5.88	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
5.88	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
5.88	Single	7L0R	Neurotensin-(8-13)	7L0R-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
5.88	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
5.88	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
5.88	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
5.88	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
5.88	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
5.88	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
5.88	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3; ZNRF3
5.88	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
5.88	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
5.88	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
5.88	Single	8Y69	R-spondin-2	8Y69-LGR4; LGR4-R-spondin-2-ZNRF3
5.88	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
5.88	Single	9KWG	C5a	9KWG-C5a₁-C5a-Go/β1/γ2
5.88	Single	9L3Y	Chemerin	9L3Y-CML2-Chemerin-Gi1/β1/γ2
5.88	Single	9MEJ	Gp120	9MEJ-CXCR4-Gp120
5.88	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
5.88	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
5.88	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-C5-guano-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-DAMGO-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
5.88	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
5.88	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
5.88	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.88	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
5.56	Single	6DO1	(Sar1,Ile8)-Angiotensin II	6DO1-AT₁-(Sar1,Ile8)-Angiotensin II
5.56	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
5.56	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
5.56	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
5.56	Single	7F1Q	CCL3	7F1Q-CCR5-CCL3-Gi1/β1/γ2
5.56	Single	7PIV	Afamelanotide	7PIV-MC₄-Afamelanotide-Gs/β1/γ2
5.56	Single	7RKM	CX3CL1	7RKM-US28-CX3CL1-Gi1/β1/γ2
5.56	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
5.56	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
5.56	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
5.56	Single	7VBI	Tirzepatide (non-acylated)	7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
5.56	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
5.56	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8JZZ	C5a-des-Arg	8JZZ-C5a₁-C5a-des-Arg-Go/β1/γ2
5.56	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3; ZNRF3
5.56	Single	8Z7J	JN241-9	8Z7J-Apelin-JN241-9-Gi1/β1/γ2
5.56	Single	9KB8	R-spondin-2	9KB8-LGR4-R-spondin-2-ZNRF3; ZNRF3
5.56	Single	9KB9	R-spondin-2	9KB9-LGR4; LGR4-R-spondin-2-ZNRF3; ZNRF3
5.56	Single	9ME1	CXCL12	9ME1-CXCR4-CXCL12
5.56	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
5.56	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
5.56	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.56	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM-5541-Gi1/β1/γ2 7EW2-S1P₃-FTY720-P-Gi1/β1/γ2
5.56	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
5.26	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
5.26	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
5.26	Single	6MEO	Gp160; CD4	6MEO-CCR5-Gp160; CD4
5.26	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
5.26	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
5.26	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Single	8K6N	Neuropeptide-Y	8K6N-Y₂-Neuropeptide-Y-Gi2/β1/γ1
5.26	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
5.26	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
5.26	Single	8XZH	MM07	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2
5.26	Single	8Y69	R-spondin-2	8Y69-LGR4; LGR4-R-spondin-2-ZNRF3
5.26	Single	8YFO	Ac-LA-PTH Analog	8YFO-PTH1-Ac-LA-PTH Analog-chim(NtGi1-Gs)/β1/γ2
5.26	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
5.26	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
5.26	Single	9KB9	R-spondin-2	9KB9-LGR4; LGR4-R-spondin-2-ZNRF3; ZNRF3
5.26	Single	9LXR	LA-PTH Analog	9LXR-PTH1-LA-PTH Analog-Arrestin2
5.26	Single	9M1O	Neuropeptide-FF	9M1O-NPFF2-Neuropeptide-FF-Gi1/β1/γ2
5.26	Single	9MEU	CXCL12	9MEU-CXCR4-CXCL12
5.26	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
5.26	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.26	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
5.26	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
5.26	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
5.26	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
5.26	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
5.26	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.26	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.26	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
5.00	Single	6M1I	PACAP27	6M1I-PAC₁-PACAP27-Gs/β1/γ2
5.00	Single	6MET	Gp160; CD4	6MET-CCR5-Gp160; CD4
5.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
5.00	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7F6G	(Sar1)-Angiotensin II	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.00	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
5.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
5.00	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
5.00	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
5.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8XZJ	WN353	8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2
5.00	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
5.00	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
5.00	Single	9BLC	Cagrilintide (non-acylated)	9BLC-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
5.00	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
5.00	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
5.00	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
5.00	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.00	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
5.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
5.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
5.00	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
5.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.00	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
5.00	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
5.00	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
5.00	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
5.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
5.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
5.00	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
4.76	Single	5YQZ	NNC1702	5YQZ-Glucagon-NNC1702
4.76	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
4.76	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
4.76	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
4.76	Single	7F9Y	Ghrelin	7F9Y-Ghrelin-Ghrelin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
4.76	Single	7P02	Substance-P	7P02-NK₁-Substance-P-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7TYH	Calcitonin	7TYH-CT (AMY2)-Calcitonin-Gs/β1/γ2; RAMP2
4.76	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
4.76	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
4.76	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.76	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.76	Single	7Y64	C5a	7Y64-C5a₁-C5a-Gi1/β1/γ2
4.76	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8HK5	C5a	8HK5-C5a₁-C5a-Gi1/β1/γ2
4.76	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
4.76	Single	8IA2	C5a	8IA2-C5a₁-C5a-Go/β1/γ2
4.76	Single	8XQE	Apelin-13	8XQE-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
4.76	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8YG4	LA-PTH Analog	8YG4-PTH1-LA-PTH Analog-chim(NtGi1-Gs)/β1/γ2
4.76	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.76	Single	9E2A	GLP-1	9E2A-GLP-1-GLP-1-Gs/β1/γ2
4.76	Single	9JFY	Neuropeptide-SF	9JFY-NPFF2-Neuropeptide-SF-Gi1/β1/γ2
4.76	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
4.76	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
4.76	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
4.76	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
4.76	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
4.76	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin; Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
4.76	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-CXCL8-Gi1/β1/γ2 6LFM-CXCR2-CXCL8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-CCL3-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
4.76	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
4.76	Consensus	pac_on	Orthosteric Ligand	pac1_on
4.76	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
4.55	Single	4XT3	CX3CL1	4XT3-US28-CX3CL1
4.55	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
4.55	Single	6FJ3	PTH	6FJ3-PTH1-PTH
4.55	Single	6NBF	LA-PTH Analog	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2
4.55	Single	6NBI	LA-PTH Analog	6NBI-PTH1-LA-PTH Analog-Gs/β1/γ2
4.55	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
4.55	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
4.55	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
4.55	Single	7VAB	Tirzepatide (non-acylated)	7VAB-GIP-Tirzepatide (non-acylated)-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
4.55	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.55	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
4.55	Single	9BLB	Cagrilintide (non-acylated)	9BLB-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
4.55	Single	9BLW	Cagrilintide (non-acylated)	9BLW-CT (AMY1)-Cagrilintide (non-acylated)-Gs/β1/γ2; RAMP1
4.55	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
4.55	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
4.55	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
4.55	Single	9P92	VIP	9P92-PAC₁-VIP-Gs/β1/γ2
4.55	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
4.55	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
4.55	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-CCL3-Gi1/β1/γ2
4.55	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
4.55	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.55	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.55	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
4.55	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
4.55	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
4.55	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
4.55	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
4.55	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
4.55	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.55	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
4.35	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
4.35	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
4.35	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
4.35	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
4.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
4.35	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
4.35	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
4.35	Single	7S1M	Exendin-4-D-Ala	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2
4.35	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
4.35	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
4.35	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.35	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
4.35	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Single	8FU6	ZP3780	8FU6-Glucagon-ZP3780-Gs/β1/γ2
4.35	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8ZH8	QRFP26	8ZH8-QRFP-QRFP26-Gq/β1/γ1
4.35	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
4.35	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
4.35	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
4.35	Single	9P94	PACAP27	9P94-PAC₁-PACAP27-Gs/β1/γ2
4.35	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
4.35	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
4.35	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
4.35	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
4.35	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
4.35	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
4.17	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
4.17	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
4.17	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
4.17	Single	6NBH	LA-PTH Analog	6NBH-PTH1-LA-PTH Analog-Gs/β1/γ2
4.17	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
4.17	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
4.17	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.17	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
4.17	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.17	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
4.17	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.17	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
4.17	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
4.17	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
4.17	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
4.17	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
4.17	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
4.17	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
4.17	Single	9P93	VIP	9P93-PAC₁-VIP-Gs/β1/γ2
4.17	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
4.17	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
4.17	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.17	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
4.17	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
4.17	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.17	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
4.17	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
4.17	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.17	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.00	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
4.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
4.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
4.00	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
4.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
4.00	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
4.00	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-CCL3-Gi1/β1/γ2
4.00	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
4.00	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.00	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
4.00	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
3.85	Single	6LPB	PACAP27	6LPB-PAC₁-PACAP27-Gs/β1/γ1
3.85	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
3.85	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
3.85	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
3.85	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.85	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
3.85	Single	8FLU	LA-PTH Analog	8FLU-PTH1-LA-PTH Analog-Gs/β1/γ2
3.85	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.85	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
3.85	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.85	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.85	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
3.70	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
3.70	Single	6WPW	ZP3780	6WPW-Glucagon-ZP3780-Gs/β1/γ2
3.70	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.70	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
3.70	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
3.70	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
3.70	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.70	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.57	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
3.57	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
3.57	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.57	Single	7Y36	PTH	7Y36-PTH1-PTH-Gs/β1/γ2
3.57	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
3.57	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
3.57	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
3.57	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
3.57	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
3.57	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.45	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.45	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.45	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
3.45	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
3.33	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.33	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.33	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.23	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
3.23	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
3.23	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.12	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
3.03	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
3.03	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
2.86	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
2.78	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:A796	X:X:?1	3.71	0	No	Yes	8	0	1	0
R:R:I798	R:R:P799	5.08	0	No	No	7	9	2	1
R:R:P799	S:S:I800	5.08	9	No	Yes	9	8	1	1
R:R:P799	X:X:?1	13.55	9	No	Yes	9	0	1	0
R:R:I800	S:S:I800	4.42	9	Yes	Yes	8	8	2	1
S:S:P582	S:S:W583	2.7	0	No	Yes	4	6	2	1
S:S:W583	S:S:Y812	4.82	0	Yes	No	6	7	1	2
S:S:T816	S:S:W583	3.64	0	No	Yes	8	6	2	1
S:S:W583	X:X:?1	8.05	0	Yes	Yes	6	0	1	0
S:S:F797	S:S:I800	3.77	0	Yes	Yes	9	8	2	1
S:S:F797	S:S:S821	6.61	0	Yes	No	9	8	2	1
S:S:I800	S:S:T817	3.04	9	Yes	No	8	8	1	2
S:S:I800	X:X:?1	15.14	9	Yes	Yes	8	0	1	0
S:S:E809	S:S:I813	2.73	0	Yes	No	8	5	2	1
S:S:I813	S:S:T817	3.04	0	No	No	5	8	1	2
S:S:I813	X:X:?1	8.41	0	No	Yes	5	0	1	0
S:S:V820	X:X:?1	10.54	0	No	Yes	7	0	1	0
S:S:S821	X:X:?1	10.62	0	No	Yes	8	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
87.50	Single	9MBC	AZ12216052	9MBC-mGlu8; mGlu8-DCPG-AZ12216052
33.33	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
30.77	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
18.75	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
17.65	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
17.39	Single	6NIY	Calcitonin-1	6NIY-CT-Calcitonin-1-Gs/β1/γ2
15.38	Single	6P9X	Corticoliberin-1	6P9X-CRF₁-Corticoliberin-1-Gs/β1/γ2
13.64	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
13.33	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
13.33	Single	7UTZ	DPPC	7UTZ-TSH-TSH-DPPC-Gs/β1/γ2
12.90	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
12.50	Single	5UEN	DU172	5UEN-A₁-DU172
12.50	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7RBT	LSN3556672	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
12.00	Single	7TYH	Calcitonin	7TYH-CT (AMY2)-Calcitonin-Gs/β1/γ2; RAMP2
12.00	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
11.76	Single	9B9Z	MRI-1867	9B9Z-CB₁-MRI-1867
11.76	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
11.76	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
11.54	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.11	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
11.11	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
11.11	Single	8I2G	PubChem 67530240	8I2G-FSH-FSH-PubChem 67530240-Gs/β1/γ2
11.11	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
10.71	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
10.53	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
10.53	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
10.53	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
10.53	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
10.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
10.00	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
9.68	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
9.52	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.52	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
9.38	Single	7Y36	PTH	7Y36-PTH1-PTH-Gs/β1/γ2
9.38	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
9.09	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
9.09	Single	7XKD	Dehydroepiandrosterone	7XKD-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
9.09	Single	7XKE	Dehydroepiandrosterone	7XKE-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8IEB	PubChem 134746894	8IEB-GPR156; GPR156-PubChem 134746894
9.09	Single	8IEI	PubChem 134746894	8IEI-GPR156; GPR156-PubChem 134746894
9.09	Single	8IEI	PubChem 134746894	8IEI-GPR156; GPR156-PubChem 134746894
9.09	Single	8IEP	PubChem 134746894	8IEP-GPR156; GPR156-PubChem 134746894
9.09	Single	8IEP	PubChem 134746894	8IEP-GPR156; GPR156-PubChem 134746894
9.09	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
8.70	Single	8IEB	PubChem 134746894	8IEB-GPR156; GPR156-PubChem 134746894
8.70	Single	9JFK	(Pen5)-Urotensin II	9JFK-UT-(Pen5)-Urotensin II-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.70	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
8.33	Single	6VN7	PACAP27	6VN7-VPAC₁-PACAP27-Gs/β1/γ2
8.33	Single	8Y02	All-trans-Retinal	8Y02-OPN1SW-All-trans-Retinal-Gi1/β1/γ2
8.33	Single	9LXR	LA-PTH Analog	9LXR-PTH1-LA-PTH Analog-Arrestin2
8.33	Single	9M42	A1L8O	9M42-GPR139-A1L8O-chim(Gs-CtGq)/β1/γ2
8.33	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
8.00	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2; STE2-α-factor mating pheromone-Gi1/STE4/γ2
8.00	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8IED	PubChem 134746894	8IED-GPR156; GPR156-PubChem 134746894-Go/β1/γ2
8.00	Single	8IED	PubChem 134746894	8IED-GPR156; GPR156-PubChem 134746894-Go/β1/γ2
8.00	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
8.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
7.69	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
7.69	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
7.69	Single	8ITF	DMCHA	8ITF-TAA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8IW7	2-Phenylethylamine	8IW7-TAA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
7.69	Single	8Y6W	4-CMTB	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
7.69	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
7.69	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
7.69	Single	9JG1	Adriforant	9JG1-H₄-Adriforant
7.69	Single	9LRC	Histamine	9LRC-H₄-Histamine
7.69	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
7.69	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
7.69	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
7.69	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
7.69	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
7.69	Consensus	pac_on	Orthosteric Ligand	pac1_on
7.69	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
7.41	Single	6NBF	LA-PTH Analog	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2
7.41	Single	6P9Y	PACAP27	6P9Y-PAC₁-PACAP27-Gs/β1/γ2
7.41	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
7.41	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
7.41	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
7.41	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
7.41	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
7.41	Single	9BLW	Cagrilintide (non-acylated)	9BLW-CT (AMY1)-Cagrilintide (non-acylated)-Gs/β1/γ2; RAMP1
7.41	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
7.41	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
7.41	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
7.41	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
7.41	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
7.14	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
7.14	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
7.14	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2; STE2-α-factor mating pheromone-Gi1/STE4/γ2
7.14	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
7.14	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
7.14	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
7.14	Single	7LD3	MIPS521	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
7.14	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
7.14	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
7.14	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
7.14	Single	7XKF	Dehydroepiandrosterone	7XKF-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
7.14	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
7.14	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
7.14	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
7.14	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
7.14	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
7.14	Single	9B9Y	Taranabant	9B9Y-CB₁-Taranabant
7.14	Single	9EPR	All-trans-Retinal	9EPR-Rhodopsin-All-trans-Retinal-Gi1/β1/γ2
7.14	Single	9JED	Histamine	9JED-H₄-Histamine-PO4-Gi1/β1/γ2
7.14	Single	9JEQ	Histamine	9JEQ-H₃-Histamine-Gi1/β1/γ2
7.14	Single	9L42	Histamine	9L42-H₄-Histamine-Gi1/β1/γ2
7.14	Single	9P94	PACAP27	9P94-PAC₁-PACAP27-Gs/β1/γ2
7.14	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
7.14	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
7.14	Consensus	neurotensin_off	Orthosteric Ligand	nts1_off
7.14	Consensus	nts1_off	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
6.90	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
6.90	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
6.90	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
6.90	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
6.90	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
6.90	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
6.90	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
6.90	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
6.90	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
6.90	Single	9P93	VIP	9P93-PAC₁-VIP-Gs/β1/γ2
6.90	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
6.90	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
6.67	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
6.67	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
6.67	Single	5U09	Taranabant	5U09-CB₁-Taranabant
6.67	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
6.67	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
6.67	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
6.67	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
6.67	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
6.67	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
6.67	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
6.67	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.67	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.67	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
6.67	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
6.67	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
6.67	Single	8IW4	Spermidine	8IW4-TAA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8IWE	Spermidine	8IWE-TAA9-Spermidine
6.67	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
6.67	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
6.67	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
6.67	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
6.67	Single	9CLW	4-CMTB	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
6.67	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
6.67	Single	9JKX	Acifran	9JKX-HCA₃-Acifran-Gi1/β1/γ2
6.67	Single	9KPE	Salicin	9KPE-TAS2R16-Salicin-Gi1/β1/γ2
6.67	Single	9LKD	PL45	9LKD-OR5V1-PL45
6.67	Single	9LLB	DOI-NBOMe	9LLB-5-HT_2A-DOI-NBOMe-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-1-Gs/β1/γ2
6.67	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
6.67	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
6.67	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
6.67	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.67	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.45	Single	6LPB	PACAP27	6LPB-PAC₁-PACAP27-Gs/β1/γ1
6.45	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
6.45	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
6.25	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
6.25	Single	6FFI	MPEP	6FFI-mGlu₅-MPEP
6.25	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
6.25	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
6.25	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
6.25	Single	6WPW	ZP3780	6WPW-Glucagon-ZP3780-Gs/β1/γ2
6.25	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
6.25	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
6.25	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
6.25	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
6.25	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
6.25	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
6.25	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
6.25	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
6.25	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
6.25	Single	8PM2	DMCHA	8PM2-TA7-DMCHA-Gs/β1/γ2
6.25	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
6.25	Single	8Y01	All-trans-Retinal	8Y01-Opsin1MW-All-trans-Retinal-Gi1/β1/γ2
6.25	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	9BA0	MRI-1891	9BA0-CB₁-MRI-1891
6.25	Single	9JQY	TG6-129	9JQY-EP₄-TG6-129
6.25	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Single	9KXS	EP67	9KXS-C5a₁-EP67-Go/β1/γ2
6.25	Single	9LKB	PL45	9LKB-OR5V1-PL45-chim(NtGi1-Gs)/β1
6.25	Single	9PXX	Naloxone	9PXX-μ-Naloxone-GDPβS-Gi1/β1/γ2
6.25	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
6.25	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-1-Gs/β1/γ2
6.25	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
6.25	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
6.25	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
6.25	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
6.06	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
5.88	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
5.88	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
5.88	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
5.88	Single	4U16	N-methyl-Scopolamine	4U16-M₃-N-methyl-Scopolamine
5.88	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
5.88	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
5.88	Single	5YC8	N-methyl-Scopolamine	5YC8-M₂-N-methyl-Scopolamine
5.88	Single	5ZK8	N-methyl-Scopolamine	5ZK8-M₂-N-methyl-Scopolamine
5.88	Single	5ZKC	N-methyl-Scopolamine	5ZKC-M₂-N-methyl-Scopolamine
5.88	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
5.88	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
5.88	Single	6GPS	MK0812	6GPS-CCR2-MK0812
5.88	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
5.88	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
5.88	Single	7M3J	NPS-2143; PO4	7M3J-CaS; CaS-NPS-2143; PO4
5.88	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
5.88	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.88	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
5.88	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
5.88	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
5.88	Single	8ZQE	GPR15L(CT)	8ZQE-GPR15-GPR15L(CT)-Gi1/β1/γ1
5.88	Single	9JEA	Atropine	9JEA-M₁-Atropine
5.88	Single	9JQZ	Grapiprant	9JQZ-EP₄-Grapiprant
5.88	Single	9UAZ	Atropine	9UAZ-M₁-Atropine
5.88	Consensus	cck_off	Orthosteric Ligand	ccka_off
5.88	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
5.88	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
5.88	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
5.88	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
5.88	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
5.88	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
5.56	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
5.56	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
5.56	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
5.56	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
5.56	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
5.56	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
5.56	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
5.56	Single	6GPX	MK0812	6GPX-CCR2-MK0812
5.56	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
5.56	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
5.56	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
5.56	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
5.56	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
5.56	Single	7EPF	NAM597	7EPF-mGlu₂-NAM597
5.56	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
5.56	Single	7M3J	NPS-2143; PO4	7M3J-CaS; CaS-NPS-2143; PO4
5.56	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.56	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
5.56	Single	7WIG	L-054264	7WIG-SST2-L-054264-Gi1/β1/γ2
5.56	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
5.56	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
5.56	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
5.56	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
5.56	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
5.56	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.56	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.56	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.56	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.56	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.56	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.56	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.56	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.56	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
5.56	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
5.56	Single	8ZYT	Neurotensin-(8-13)	8ZYT-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
5.56	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
5.56	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
5.56	Single	9PXY	Naloxone	9PXY-μ-Naloxone-GDPβS-Gi1/β1/γ2
5.56	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
5.56	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.56	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.56	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
5.56	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.41	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
5.26	Single	2YDV	NECA	2YDV-A_2A-NECA
5.26	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
5.26	Single	3ZEV	Neurotensin-(7-13)	3ZEV-NTS₁-Neurotensin-(7-13)
5.26	Single	4BV0	Neurotensin-(7-13)	4BV0-NTS₁-Neurotensin-(7-13)
5.26	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
5.26	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
5.26	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
5.26	Single	5G53	NECA	5G53-A_2A-NECA-Gs
5.26	Single	5V56	TC114	5V56-SMO-TC114
5.26	Single	5V57	TC114	5V57-SMO-TC114
5.26	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.26	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
5.26	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.26	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
5.26	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
5.26	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.26	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
5.26	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
5.26	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
5.26	Single	7P2L	4YI	7P2L-mGlu₅-4YI
5.26	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
5.26	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
5.26	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.26	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.26	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
5.26	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
5.26	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
5.26	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
5.26	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
5.26	Single	8FMZ	Neurotensin-(8-13)	8FMZ-NTS₁-Neurotensin-(8-13)-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8HPT	C5a (C-terminal peptide)	8HPT-C5a₁-C5a (C-terminal peptide)-Go/β1/γ2
5.26	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
5.26	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
5.26	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.26	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.26	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
5.26	Single	8XZI	CMF-019	8XZI-Apelin; Apelin-CMF-019-Gi1/β1/γ2
5.26	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
5.26	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
5.26	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
5.26	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9E9S	PGD2	9E9S-DP₁-PGD2-Gs/β1/γ1
5.26	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
5.26	Single	9PY3	Loperamide	9PY3-μ-Loperamide-GDPβS-Gi1/β1/γ2
5.26	Single	9UCP	Iperoxo	9UCP-M₁-Iperoxo-G11(CT)
5.26	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.26	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.26	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
5.26	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
5.26	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
5.26	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
5.26	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
5.26	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
5.26	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
5.00	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
5.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
5.00	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
5.00	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
5.00	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
5.00	Single	7EPE	NAM563	7EPE-mGlu₂-NAM563
5.00	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
5.00	Single	7L0S	Neurotensin-(8-13)	7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
5.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
5.00	Single	7W0L	PubChem 122701908	7W0L-Apelin; Apelin-PubChem 122701908-Gi1/β1/γ2
5.00	Single	7W0N	Elabela	7W0N-Apelin; Apelin-Elabela-Gi1/β1/γ2
5.00	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
5.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
5.00	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
5.00	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
5.00	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8JWY	2-118	8JWY-A_2A-2-118
5.00	Single	8JWZ	Etrumadenant	8JWZ-A_2A-Etrumadenant-Na
5.00	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
5.00	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
5.00	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
5.00	Single	9EK0	Iperoxo	9EK0-M₅-Iperoxo-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
5.00	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
5.00	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
5.00	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
5.00	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
5.00	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
5.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.00	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.00	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	4BUO	Neurotensin-(8-13)	4BUO-NTS₁-Neurotensin-(8-13)
4.76	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.76	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.76	Single	6UP7	Neurotensin-(8-13)	6UP7-NTS₁-Neurotensin-(8-13)-Arrestin2
4.76	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
4.76	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
4.76	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
4.76	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
4.76	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
4.76	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	8FN0	Neurotensin-(8-13)	8FN0-NTS₁-Neurotensin-(8-13)-SBI-553-chim(NtGi1-Go)/β1/γ2
4.76	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
4.76	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
4.76	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
4.76	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
4.76	Single	9IZF	LPA	9IZF-LPA₁-LPA-Gi1/β1/γ2
4.76	Single	9KUG	EP67	9KUG-C5a₁-EP67-Go/β1/γ2
4.76	Single	9KV8	TLQP21	9KV8-C3a_B-TLQP21-Go/β1/γ2
4.76	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
4.55	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
4.55	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
4.55	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
4.55	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
4.55	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
4.55	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.55	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
4.55	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
4.55	Single	7XN9	L-054522	7XN9-SST2-L-054522
4.55	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
4.55	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs/β1/γ2
4.55	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
4.55	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
4.55	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
4.55	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.55	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.55	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.35	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
4.35	Single	7L0R	Neurotensin-(8-13)	7L0R-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
4.35	Single	7QA8	Antagonist Peptide	7QA8-STE2; STE2-Antagonist Peptide
4.35	Single	7QA8	Antagonist Peptide	7QA8-STE2; STE2-Antagonist Peptide
4.35	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
4.35	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
4.35	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
4.35	Single	8IZB	Lysophosphatidylserine (UBL)	8IZB-GPR174-Lysophosphatidylserine (UBL)-Gs/β1/γ2
4.35	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
4.35	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
4.35	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
4.35	Single	9KWG	C5a	9KWG-C5a₁-C5a-Go/β1/γ2
4.35	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
4.35	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
4.17	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
4.17	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
4.17	Single	7VBI	Tirzepatide (non-acylated)	7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
4.17	Single	7W0N	Elabela	7W0N-Apelin; Apelin-Elabela-Gi1/β1/γ2
4.17	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
4.17	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
4.17	Single	9KV6	TLQP21	9KV6-C3a_B-TLQP21-Go/β1/γ2
4.17	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
4.17	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
4.17	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
4.17	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
4.00	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
4.00	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
4.00	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
4.00	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
4.00	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
4.00	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
4.00	Single	9B54	VIP36	9B54-CB₁-VIP36-Gi1/β1/γ2
4.00	Single	9B5Y	LA-PTH Analog	9B5Y-PTH1-LA-PTH Analog-chim(NtGi1-Gq)/β1/γ2
4.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
4.00	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.00	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
4.00	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
4.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
4.00	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-14-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.00	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
3.85	Single	6M1I	PACAP27	6M1I-PAC₁-PACAP27-Gs/β1/γ2
3.85	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
3.85	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
3.85	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.85	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.85	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
3.85	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
3.85	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
3.85	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8WST	MCH	8WST-MCH2-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.85	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
3.85	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
3.85	Single	9BLC	Cagrilintide (non-acylated)	9BLC-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
3.85	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
3.85	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
3.85	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
3.85	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
3.85	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
3.85	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
3.70	Single	5YQZ	NNC1702	5YQZ-Glucagon-NNC1702
3.70	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
3.70	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
3.70	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2; STE2-α-factor mating pheromone
3.70	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
3.70	Single	7XV3	Lysophosphatidylserine (WJS)	7XV3-GPR174-Lysophosphatidylserine (WJS)-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7Y64	C5a	7Y64-C5a₁-C5a-Gi1/β1/γ2
3.70	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
3.70	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.70	Single	8HK5	C5a	8HK5-C5a₁-C5a-Gi1/β1/γ2
3.70	Single	8IA2	C5a	8IA2-C5a₁-C5a-Go/β1/γ2
3.70	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
3.70	Single	8XQE	Apelin-13	8XQE-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
3.70	Single	8YG4	LA-PTH Analog	8YG4-PTH1-LA-PTH Analog-chim(NtGi1-Gs)/β1/γ2
3.70	Single	9E2A	GLP-1	9E2A-GLP-1-GLP-1-Gs/β1/γ2
3.70	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
3.70	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
3.70	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
3.70	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-Lysophosphatidylserine (WJS)-chim(NtGi2-G13)/β1/γ2
3.70	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.57	Single	4XT3	CX3CL1	4XT3-US28-CX3CL1
3.57	Single	6FJ3	PTH	6FJ3-PTH1-PTH
3.57	Single	6NBI	LA-PTH Analog	6NBI-PTH1-LA-PTH Analog-Gs/β1/γ2
3.57	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
3.57	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2; STE2-α-factor mating pheromone
3.57	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
3.57	Single	7VAB	Tirzepatide (non-acylated)	7VAB-GIP-Tirzepatide (non-acylated)-chim(NtGi1-Gs)/β1/γ2
3.57	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
3.57	Single	9BLB	Cagrilintide (non-acylated)	9BLB-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
3.57	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
3.57	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
3.57	Single	9P92	VIP	9P92-PAC₁-VIP-Gs/β1/γ2
3.57	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
3.57	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.57	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
3.57	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.57	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.57	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
3.57	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.45	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
3.45	Single	7EIB	Kallidin-des-Arg10	7EIB-BK₁-Kallidin-des-Arg10-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2; STE2-α-factor mating pheromone
3.45	Single	7S1M	Exendin-4-D-Ala	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2
3.45	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
3.45	Single	8FU6	ZP3780	8FU6-Glucagon-ZP3780-Gs/β1/γ2
3.45	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
3.45	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
3.45	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
3.45	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.45	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.45	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
3.45	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
3.45	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-Lysophosphatidylserine (WJS)-chim(NtGi2-G13)/β1/γ2
3.45	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
3.33	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
3.33	Single	6NBH	LA-PTH Analog	6NBH-PTH1-LA-PTH Analog-Gs/β1/γ2
3.33	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
3.33	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
3.33	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
3.33	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2; STE2-α-factor mating pheromone
3.33	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.33	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.33	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
3.33	Single	8KGG	Lysophosphatidylserine (WJS)	8KGG-P2Y10-Lysophosphatidylserine (WJS)-chim(NtGi2-G13)/β1/γ2
3.33	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
3.33	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.33	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.33	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
3.33	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
3.23	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
3.23	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
3.23	Single	8ZJE	TAK448	8ZJE-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ1
3.23	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
3.23	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
3.12	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.12	Single	8FLU	LA-PTH Analog	8FLU-PTH1-LA-PTH Analog-Gs/β1/γ2
3.12	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.03	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.03	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
3.03	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
3.03	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.03	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
2.94	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.94	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
2.94	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
2.94	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
2.94	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
2.94	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
2.86	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.86	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
2.78	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.78	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.70	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
2.70	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:K71	7.88	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:R75	7.64	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:S156	6.29	1	Yes	No	0	9	0	1
L:L:?1	R:R:T179	8.24	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:Y227	15.56	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:D309	2.84	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:K314	3.94	1	Yes	No	0	5	0	1
R:R:K68	R:R:K71	8.62	0	No	Yes	5	5	2	1
R:R:K71	R:R:R75	3.71	1	Yes	Yes	5	4	1	1
R:R:E284	R:R:K71	4.05	0	No	Yes	3	5	2	1
R:R:R75	R:R:Y176	6.17	1	Yes	Yes	4	7	1	2
R:R:E399	R:R:R75	13.96	1	Yes	Yes	5	4	2	1
R:R:K401	R:R:R75	8.66	1	No	Yes	4	4	2	1
R:R:A180	R:R:S156	3.42	0	No	No	7	9	2	1
R:R:T179	R:R:V196	3.17	1	Yes	Yes	7	7	1	2
R:R:D199	R:R:T179	10.12	0	Yes	Yes	8	7	2	1
R:R:D309	R:R:T179	2.89	1	Yes	Yes	8	7	1	1
R:R:D199	R:R:Q202	5.22	0	Yes	Yes	8	9	2	2
R:R:D199	R:R:Y227	4.6	0	Yes	Yes	8	7	2	1
R:R:F281	R:R:Q202	3.51	1	Yes	Yes	7	9	2	2
R:R:Q202	R:R:S308	4.33	1	Yes	Yes	9	8	2	2
R:R:D309	R:R:Q202	6.53	1	Yes	Yes	8	9	1	2
R:R:G228	R:R:Y227	4.35	1	No	Yes	8	7	2	1
R:R:F281	R:R:Y227	6.19	1	Yes	Yes	7	7	2	1
R:R:S308	R:R:Y227	6.36	1	Yes	Yes	8	7	2	1
R:R:D309	R:R:Y227	8.05	1	Yes	Yes	8	7	1	1
R:R:S310	R:R:Y227	8.9	1	No	Yes	6	7	2	1
R:R:F281	R:R:G228	3.01	1	Yes	No	7	8	2	2
R:R:F281	R:R:S308	10.57	1	Yes	Yes	7	8	2	2
R:R:E284	R:R:K314	9.45	0	No	No	3	5	2	1
R:R:D309	R:R:S308	2.94	1	Yes	Yes	8	8	1	2
R:R:S308	R:R:S310	3.26	1	Yes	No	8	6	2	2
R:R:D309	R:R:S310	2.94	1	Yes	No	8	6	1	2
R:R:K314	R:R:P317	3.35	0	No	No	5	3	1	2
R:R:E399	R:R:K401	4.05	1	Yes	No	5	4	2	2
R:R:G72	R:R:K71	1.74	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
100.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
100.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
100.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
100.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
100.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626
100.00	Single	7DD5	Ca	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS; CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
100.00	Single	7DTT	Ca	7DTT-CaS; CaS-Ca-Ca
100.00	Single	7DTT	Ca	7DTT-CaS; CaS-Ca-Ca
100.00	Single	7DTU	Tryptophan	7DTU-CaS; CaS-Tryptophan
100.00	Single	7DTU	Tryptophan	7DTU-CaS; CaS-Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS; CaS-Ca-Ca; Tryptophan
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS; CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS; CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet	7M3F-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet	7M3F-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7SIL	Ca	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIL	Ca	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	7SIL-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
100.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TQB	Ca; LY379268	8TQB-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TQB	Ca; LY379268	8TQB-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8WG9	PubChem 179394	8WG9-mGlu4; mGlu2-PubChem 179394
100.00	Single	8WGB	Glutamate	8WGB-mGlu4; mGlu2-Glutamate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGB	Glutamate	8WGB-mGlu4; mGlu2-Glutamate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGC	LY379268	8WGC-mGlu2; mGlu4-LY379268
100.00	Single	8WGD	LY341495; CPPG	8WGD-mGlu4; mGlu2-LY341495; CPPG
100.00	Single	8WGD	LY341495; CPPG	8WGD-mGlu4; mGlu2-LY341495; CPPG
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS; CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WVX	Norrin	8WVX-LGR4-Norrin
100.00	Single	8WVY	Norrin	8WVY-LGR4-Norrin
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU29
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU29
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
100.00	Single	9ASB	Ca	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AVG	Ca	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVL	Ca	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVL-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi3/β2/γ2
100.00	Single	9AXF	Ca	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AYF	Ca	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
100.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
100.00	Single	9C1P	Ca	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS; CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C2F	Ca	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS; CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2; Arrestin2
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2; Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9KB7	R-spondin-2	9KB7-LGR4-R-spondin-2
100.00	Single	9KGK	NB18	9KGK-LGR4-NB18
100.00	Single	9KHH	Norrin	9KHH-LGR4-Norrin
100.00	Single	9MBA	Glutamate	9MBA-mGlu8; mGlu8-Glutamate-Arrestin2 ; Arrestin2
100.00	Single	9MBA	Glutamate	9MBA-mGlu8; mGlu8-Glutamate-Arrestin2 ; Arrestin2
100.00	Single	9MBB	LY341495	9MBB-mGlu8; mGlu8-LY341495
100.00	Single	9MBB	LY341495	9MBB-mGlu8; mGlu8-LY341495
100.00	Single	9MBC	DCPG	9MBC-mGlu8; mGlu8-DCPG-AZ12216052
100.00	Single	9S37	NB21	9S37-LGR4-NB21
100.00	Single	9S38	NB21	9S38-LGR4-NB21
100.00	Single	9UTB	Sucralose	9UTB-TAS1R2; TAS1R3-Sucralose
50.00	Single	7DD6	Ca	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS; CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD7	Ca	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS; CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	9ASB	Ca	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9ASB-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9AVG	Ca	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AVG-CaS; CaS-Ca-Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AYF	Ca	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
50.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AYF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-Gi1/β1/γ2
33.33	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
33.33	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
25.00	Single	7UTZ	TSH	7UTZ-TSH-TSH-DPPC-Gs/β1/γ2
25.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
25.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
20.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
20.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
20.00	Single	8I2G	FSH	8I2G-FSH-FSH-PubChem 67530240-Gs/β1/γ2
20.00	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
16.67	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
16.67	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
14.29	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
14.29	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
14.29	Single	8JEF	PubChem 11367166	8JEF-HCA₃-PubChem 11367166-Gi1/β1/γ2
14.29	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
14.29	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
14.29	Single	9IJR	C17	9IJR-GPR52-C17-Arrestin2
14.29	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
12.50	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
12.50	Single	6LI0	C17	6LI0-GPR52-C17
12.50	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
12.50	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
12.50	Single	9B9Y	Taranabant	9B9Y-CB₁-Taranabant
12.50	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Single	9MNI	dC2_05	9MNI-CTLike-dC2_05-RAMP1
11.11	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
11.11	Single	4BWB	Neurotensin-(8-12)	4BWB-NTS₁-Neurotensin-(8-12)
11.11	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	6LFO	CXCL8	6LFO-CXCR2-CXCL8-Gi1/β1/γ2
11.11	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
11.11	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
11.11	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
11.11	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
11.11	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
11.11	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
11.11	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
11.11	Single	8YNF	CXCL8	8YNF-ACKR1-CXCL8
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Single	9KO2	CCL19	9KO2-CCR7-CCL19-Gi1/β1
11.11	Single	9KO6	CCL19	9KO6-CCR7-CCL19
11.11	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
11.11	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
11.11	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
11.11	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
10.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
10.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
10.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
10.00	Single	7UTZ	DPPC	7UTZ-TSH-TSH-DPPC-Gs/β1/γ2
10.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9BA0	MRI-1891	9BA0-CB₁-MRI-1891
10.00	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
10.00	Single	9M2F	Neuropeptide-FF	9M2F-NPFF1-Neuropeptide-FF-Gi1/β1/γ2
10.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
10.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-CXCL8-Gi1/β1/γ2
10.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
10.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
10.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.09	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.09	Single	5T04	Neurotensin-(8-13)	5T04-NTS₁-Neurotensin-(8-13)
9.09	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
9.09	Single	6D27	CAY10471	6D27-DP₂-CAY10471
9.09	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
9.09	Single	6Z4V	Neurotensin-(9-13)	6Z4V-NTS₁-Neurotensin-(9-13)
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
9.09	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
9.09	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
9.09	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
9.09	Single	7VIF	FTY720-P	7VIF-S1P₁-FTY720-P-Gi1/β1/γ2
9.09	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
9.09	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
9.09	Single	8IC0	CXCL8	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
9.09	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9MET	Gp120; CD4	9MET-CXCR4-Gp120; CD4
9.09	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
9.09	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
9.09	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
9.09	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
8.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
8.33	Single	5C1M	BU72	5C1M-μ-BU72
8.33	Single	6LFM	CXCL8	6LFM-CXCR2-CXCL8-Gi1/β1/γ2
8.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
8.33	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
8.33	Single	7C4S	S1P	7C4S-S1P₃-S1P
8.33	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
8.33	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
8.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
8.33	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
8.33	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZYT	Neurotensin-(8-13)	8ZYT-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
8.33	Single	9B9Z	MRI-1867	9B9Z-CB₁-MRI-1867
8.33	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
8.33	Single	9KO4	CCL21	9KO4-CCR7-CCL21-Gi1/β1/γ2
8.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-CXCL8-Gi1/β1/γ2
8.33	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
8.33	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
7.69	Single	3ZEV	Neurotensin-(7-13)	3ZEV-NTS₁-Neurotensin-(7-13)
7.69	Single	4BV0	Neurotensin-(7-13)	4BV0-NTS₁-Neurotensin-(7-13)
7.69	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
7.69	Single	5V56	TC114	5V56-SMO-TC114
7.69	Single	5V57	TC114	5V57-SMO-TC114
7.69	Single	6OS1	TRV026	6OS1-AT₁-TRV026
7.69	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
7.69	Single	7F1T	CCL3	7F1T-CCR5-CCL3
7.69	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
7.69	Single	7L0P	Neurotensin-(8-13)	7L0P-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.69	Single	7L0Q	Neurotensin-(8-13)	7L0Q-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.69	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
7.69	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
7.69	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
7.69	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
7.69	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
7.69	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	8FMZ	Neurotensin-(8-13)	8FMZ-NTS₁-Neurotensin-(8-13)-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8FN1	Neurotensin-(8-13)	8FN1-NTS₁-Neurotensin-(8-13)-chim(NtGi1-Go)/β1/γ2
7.69	Single	8HQC	C5a	8HQC-C5a₁-C5a-Go/β1/γ2
7.69	Single	8I2G	PubChem 67530240	8I2G-FSH-FSH-PubChem 67530240-Gs/β1/γ2
7.69	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
7.69	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
7.69	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8JZP	C5a	8JZP-C5a₁-C5a-Go/β1/γ2
7.69	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
7.69	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
7.69	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
7.69	Single	9IZG	LPA	9IZG-LPA₁-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	9JCL	ADP	9JCL-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
7.69	Single	9L16	CCL21	9L16-CCR7-CCL21
7.69	Single	9MEN	Gp120 (V3 loop)	9MEN-CXCR4-Gp120 (V3 loop)
7.69	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
7.69	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
7.69	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
7.69	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
7.69	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.69	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
7.69	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.14	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
7.14	Single	4XEE	Neurotensin-(8-13)	4XEE-NTS₁-Neurotensin-(8-13)
7.14	Single	4XES	Neurotensin-(8-13)	4XES-NTS₁-Neurotensin-(8-13)
7.14	Single	6OS0	Angiotensin II	6OS0-AT₁-Angiotensin II
7.14	Single	6OS2	TRV026	6OS2-AT₁-TRV026
7.14	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
7.14	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
7.14	Single	6YVR	Neurotensin-(6-13)	6YVR-NTS₁-Neurotensin-(6-13)
7.14	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
7.14	Single	7EW2	FTY720-P	7EW2-S1P₃-FTY720-P-Gi1/β1/γ2
7.14	Single	7L0S	Neurotensin-(8-13)	7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.14	Single	7W0N	Elabela	7W0N-Apelin; Apelin-Elabela-Gi1/β1/γ2
7.14	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
7.14	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8T3Q	Doconexent	8T3Q-FFA4-Doconexent-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	8U26	Substance-P	8U26-NK₁-Substance-P-Gs/β1/γ2
7.14	Single	8XQJ	JN241	8XQJ-Apelin; Apelin-JN241
7.14	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
7.14	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
7.14	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
7.14	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
7.14	Single	9ECJ	S-geranylgeranyl-L-glutathione	9ECJ-P2Y8-S-geranylgeranyl-L-glutathione-G13/β1/γ2
7.14	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
7.14	Single	9VIF	Neuropeptide-VF	9VIF-NPFF1-Neuropeptide-VF-Gi1/β1/γ2
7.14	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
7.14	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
7.14	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
7.14	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
7.14	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.14	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
7.14	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
7.14	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
7.14	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
7.14	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
7.14	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-C5-guano-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-DAMGO-Gi1/β1/γ2
7.14	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-C5-guano-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-DAMGO-Gi1/β1/γ2
7.14	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
7.14	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
7.14	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM-5541-Gi1/β1/γ2 7EW2-S1P₃-FTY720-P-Gi1/β1/γ2
6.67	Single	4BUO	Neurotensin-(8-13)	4BUO-NTS₁-Neurotensin-(8-13)
6.67	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
6.67	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
6.67	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
6.67	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
6.67	Single	6UP7	Neurotensin-(8-13)	6UP7-NTS₁-Neurotensin-(8-13)-Arrestin2
6.67	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
6.67	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
6.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
6.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
6.67	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
6.67	Single	8E0G	BU72	8E0G-μ-BU72
6.67	Single	8FN0	Neurotensin-(8-13)	8FN0-NTS₁-Neurotensin-(8-13)-SBI-553-chim(NtGi1-Go)/β1/γ2
6.67	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
6.67	Single	8JPF	Neurotensin-(8-13)	8JPF-NTS₁-Neurotensin-(8-13)-SBI-553
6.67	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
6.67	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
6.67	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
6.67	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
6.67	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
6.67	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9IZF	LPA	9IZF-LPA₁-LPA-Gi1/β1/γ2
6.67	Single	9KWX	C5a-des-Arg	9KWX-C5a₁-C5a-des-Arg-Go/β1/γ2
6.67	Single	9UYM	Chemerin-9	9UYM-CML2-Chemerin-9-chim(Arrestin3-CtArrestin2)
6.67	Single	9WP9	S1P	9WP9-S1P₃-S1P-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
6.67	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM-5541-Gi1/β1/γ2 7EW2-S1P₃-FTY720-P-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
6.67	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	5VBL	AMG3054	5VBL-Apelin-AMG3054
6.25	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
6.25	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
6.25	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
6.25	Single	7RKF	CX3CL1	7RKF-US28-CX3CL1-GDP-chim(NtGi1-G11)/β1/γ2
6.25	Single	7RKN	CX3CL1	7RKN-US28-CX3CL1-Gi1/β1/γ2
6.25	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
6.25	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
6.25	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
6.25	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
6.25	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs/β1/γ2
6.25	Single	8XQJ	JN241	8XQJ-Apelin; Apelin-JN241
6.25	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
6.25	Single	9KX6	C5a-des-Arg	9KX6-C5a₁-C5a-des-Arg-Go/β1/γ2
6.25	Single	9UMJ	EP54	9UMJ-C3a_B-EP54-Go/β1/γ2
6.25	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
6.25	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
6.25	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
6.25	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
6.25	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
5.88	Single	4XT1	CX3CL1	4XT1-US28-CX3CL1
5.88	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
5.88	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
5.88	Single	7L0R	Neurotensin-(8-13)	7L0R-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
5.88	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
5.88	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
5.88	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
5.88	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
5.88	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
5.88	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
5.88	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3; ZNRF3
5.88	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
5.88	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
5.88	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
5.88	Single	8Y69	R-spondin-2	8Y69-LGR4; LGR4-R-spondin-2-ZNRF3
5.88	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
5.88	Single	9KWG	C5a	9KWG-C5a₁-C5a-Go/β1/γ2
5.88	Single	9L3Y	Chemerin	9L3Y-CML2-Chemerin-Gi1/β1/γ2
5.88	Single	9MEJ	Gp120	9MEJ-CXCR4-Gp120
5.88	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
5.88	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
5.88	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-C5-guano-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-DAMGO-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
5.88	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
5.88	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
5.88	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.88	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
5.56	Single	6DO1	(Sar1,Ile8)-Angiotensin II	6DO1-AT₁-(Sar1,Ile8)-Angiotensin II
5.56	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
5.56	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
5.56	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
5.56	Single	7F1Q	CCL3	7F1Q-CCR5-CCL3-Gi1/β1/γ2
5.56	Single	7PIV	Afamelanotide	7PIV-MC₄-Afamelanotide-Gs/β1/γ2
5.56	Single	7RKM	CX3CL1	7RKM-US28-CX3CL1-Gi1/β1/γ2
5.56	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
5.56	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
5.56	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
5.56	Single	7VBI	Tirzepatide (non-acylated)	7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
5.56	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
5.56	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8JZZ	C5a-des-Arg	8JZZ-C5a₁-C5a-des-Arg-Go/β1/γ2
5.56	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3; ZNRF3
5.56	Single	8Z7J	JN241-9	8Z7J-Apelin-JN241-9-Gi1/β1/γ2
5.56	Single	9KB8	R-spondin-2	9KB8-LGR4-R-spondin-2-ZNRF3; ZNRF3
5.56	Single	9KB9	R-spondin-2	9KB9-LGR4; LGR4-R-spondin-2-ZNRF3; ZNRF3
5.56	Single	9ME1	CXCL12	9ME1-CXCR4-CXCL12
5.56	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
5.56	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
5.56	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.56	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM-5541-Gi1/β1/γ2 7EW2-S1P₃-FTY720-P-Gi1/β1/γ2
5.56	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
5.26	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
5.26	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
5.26	Single	6MEO	Gp160; CD4	6MEO-CCR5-Gp160; CD4
5.26	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
5.26	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
5.26	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Single	8K6N	Neuropeptide-Y	8K6N-Y₂-Neuropeptide-Y-Gi2/β1/γ1
5.26	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
5.26	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
5.26	Single	8XZH	MM07	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2
5.26	Single	8Y69	R-spondin-2	8Y69-LGR4; LGR4-R-spondin-2-ZNRF3
5.26	Single	8YFO	Ac-LA-PTH Analog	8YFO-PTH1-Ac-LA-PTH Analog-chim(NtGi1-Gs)/β1/γ2
5.26	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
5.26	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
5.26	Single	9KB9	R-spondin-2	9KB9-LGR4; LGR4-R-spondin-2-ZNRF3; ZNRF3
5.26	Single	9LXR	LA-PTH Analog	9LXR-PTH1-LA-PTH Analog-Arrestin2
5.26	Single	9M1O	Neuropeptide-FF	9M1O-NPFF2-Neuropeptide-FF-Gi1/β1/γ2
5.26	Single	9MEU	CXCL12	9MEU-CXCR4-CXCL12
5.26	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
5.26	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.26	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
5.26	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
5.26	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
5.26	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
5.26	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
5.26	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.26	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.26	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
5.00	Single	6M1I	PACAP27	6M1I-PAC₁-PACAP27-Gs/β1/γ2
5.00	Single	6MET	Gp160; CD4	6MET-CCR5-Gp160; CD4
5.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
5.00	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7F6G	(Sar1)-Angiotensin II	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.00	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
5.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
5.00	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
5.00	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
5.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8XZJ	WN353	8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2
5.00	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
5.00	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
5.00	Single	9BLC	Cagrilintide (non-acylated)	9BLC-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
5.00	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
5.00	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
5.00	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
5.00	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.00	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
5.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
5.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
5.00	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
5.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
5.00	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
5.00	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
5.00	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
5.00	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
5.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
5.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
5.00	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
4.76	Single	5YQZ	NNC1702	5YQZ-Glucagon-NNC1702
4.76	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
4.76	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
4.76	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
4.76	Single	7F9Y	Ghrelin	7F9Y-Ghrelin-Ghrelin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
4.76	Single	7P02	Substance-P	7P02-NK₁-Substance-P-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7TYH	Calcitonin	7TYH-CT (AMY2)-Calcitonin-Gs/β1/γ2; RAMP2
4.76	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
4.76	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
4.76	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.76	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.76	Single	7Y64	C5a	7Y64-C5a₁-C5a-Gi1/β1/γ2
4.76	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8HK5	C5a	8HK5-C5a₁-C5a-Gi1/β1/γ2
4.76	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
4.76	Single	8IA2	C5a	8IA2-C5a₁-C5a-Go/β1/γ2
4.76	Single	8XQE	Apelin-13	8XQE-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
4.76	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8YG4	LA-PTH Analog	8YG4-PTH1-LA-PTH Analog-chim(NtGi1-Gs)/β1/γ2
4.76	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.76	Single	9E2A	GLP-1	9E2A-GLP-1-GLP-1-Gs/β1/γ2
4.76	Single	9JFY	Neuropeptide-SF	9JFY-NPFF2-Neuropeptide-SF-Gi1/β1/γ2
4.76	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
4.76	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
4.76	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
4.76	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
4.76	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
4.76	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin; Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
4.76	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-CXCL8-Gi1/β1/γ2 6LFM-CXCR2-CXCL8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-CCL3-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
4.76	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
4.76	Consensus	pac_on	Orthosteric Ligand	pac1_on
4.76	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
4.55	Single	4XT3	CX3CL1	4XT3-US28-CX3CL1
4.55	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
4.55	Single	6FJ3	PTH	6FJ3-PTH1-PTH
4.55	Single	6NBF	LA-PTH Analog	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2
4.55	Single	6NBI	LA-PTH Analog	6NBI-PTH1-LA-PTH Analog-Gs/β1/γ2
4.55	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
4.55	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
4.55	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
4.55	Single	7VAB	Tirzepatide (non-acylated)	7VAB-GIP-Tirzepatide (non-acylated)-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
4.55	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.55	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
4.55	Single	9BLB	Cagrilintide (non-acylated)	9BLB-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
4.55	Single	9BLW	Cagrilintide (non-acylated)	9BLW-CT (AMY1)-Cagrilintide (non-acylated)-Gs/β1/γ2; RAMP1
4.55	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
4.55	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
4.55	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
4.55	Single	9P92	VIP	9P92-PAC₁-VIP-Gs/β1/γ2
4.55	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
4.55	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
4.55	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-CCL3-Gi1/β1/γ2
4.55	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
4.55	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.55	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.55	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
4.55	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
4.55	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
4.55	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
4.55	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
4.55	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
4.55	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.55	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
4.35	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
4.35	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
4.35	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
4.35	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
4.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
4.35	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
4.35	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
4.35	Single	7S1M	Exendin-4-D-Ala	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2
4.35	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
4.35	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
4.35	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.35	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
4.35	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Single	8FU6	ZP3780	8FU6-Glucagon-ZP3780-Gs/β1/γ2
4.35	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8ZH8	QRFP26	8ZH8-QRFP-QRFP26-Gq/β1/γ1
4.35	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
4.35	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
4.35	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
4.35	Single	9P94	PACAP27	9P94-PAC₁-PACAP27-Gs/β1/γ2
4.35	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
4.35	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
4.35	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
4.35	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
4.35	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
4.35	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
4.17	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
4.17	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
4.17	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
4.17	Single	6NBH	LA-PTH Analog	6NBH-PTH1-LA-PTH Analog-Gs/β1/γ2
4.17	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
4.17	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
4.17	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.17	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
4.17	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.17	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
4.17	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.17	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
4.17	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
4.17	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
4.17	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
4.17	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
4.17	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
4.17	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
4.17	Single	9P93	VIP	9P93-PAC₁-VIP-Gs/β1/γ2
4.17	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
4.17	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
4.17	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.17	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
4.17	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
4.17	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.17	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
4.17	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
4.17	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.17	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.00	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
4.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
4.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
4.00	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
4.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
4.00	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
4.00	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-CCL3-Gi1/β1/γ2
4.00	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
4.00	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.00	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
4.00	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
3.85	Single	6LPB	PACAP27	6LPB-PAC₁-PACAP27-Gs/β1/γ1
3.85	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
3.85	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
3.85	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
3.85	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.85	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
3.85	Single	8FLU	LA-PTH Analog	8FLU-PTH1-LA-PTH Analog-Gs/β1/γ2
3.85	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.85	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
3.85	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.85	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.85	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
3.70	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
3.70	Single	6WPW	ZP3780	6WPW-Glucagon-ZP3780-Gs/β1/γ2
3.70	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.70	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
3.70	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
3.70	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
3.70	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.70	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.57	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
3.57	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
3.57	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.57	Single	7Y36	PTH	7Y36-PTH1-PTH-Gs/β1/γ2
3.57	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
3.57	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
3.57	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
3.57	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
3.57	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
3.57	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.45	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.45	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.45	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
3.45	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
3.33	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.33	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.33	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.23	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
3.23	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
3.23	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.12	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
3.03	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
3.03	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
2.86	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
2.78	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:P582	R:R:W583	2.7	0	No	Yes	4	6	2	1
R:R:W583	R:R:Y812	4.82	0	Yes	No	6	7	1	2
R:R:T816	R:R:W583	3.64	0	No	Yes	8	6	2	1
R:R:W583	W:W:?1	9.32	0	Yes	Yes	6	0	1	0
R:R:F797	R:R:I800	3.77	0	Yes	Yes	9	8	2	1
R:R:F797	R:R:S821	6.61	0	Yes	No	9	8	2	1
R:R:I800	R:R:T817	3.04	9	Yes	No	8	8	1	2
R:R:I800	S:S:P799	5.08	9	Yes	No	8	9	1	1
R:R:I800	S:S:I800	4.42	9	Yes	Yes	8	8	1	2
R:R:I800	W:W:?1	18.99	9	Yes	Yes	8	0	1	0
R:R:E809	R:R:I813	2.73	0	Yes	No	8	5	2	1
R:R:E809	S:S:T804	7.06	0	Yes	No	8	8	2	1
R:R:I813	R:R:T817	3.04	0	No	No	5	8	1	2
R:R:I813	W:W:?1	4.38	0	No	Yes	5	0	1	0
R:R:V820	W:W:?1	10.67	0	No	Yes	7	0	1	0
R:R:S821	W:W:?1	12.29	0	No	Yes	8	0	1	0
S:S:A796	W:W:?1	3.22	0	No	Yes	8	0	1	0
S:S:I798	S:S:P799	5.08	0	No	No	7	9	2	1
S:S:P799	W:W:?1	15.12	9	No	Yes	9	0	1	0
S:S:T804	W:W:?1	4.52	0	No	Yes	8	0	1	0
S:S:G803	S:S:T804	1.82	0	No	No	8	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
87.50	Single	9MBC	AZ12216052	9MBC-mGlu8; mGlu8-DCPG-AZ12216052
31.25	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
28.57	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
22.22	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS; CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
20.00	Single	7UTZ	DPPC	7UTZ-TSH-TSH-DPPC-Gs/β1/γ2
18.75	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
17.65	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
16.67	Single	6NIY	Calcitonin-1	6NIY-CT-Calcitonin-1-Gs/β1/γ2
16.67	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
16.67	Single	8I2G	PubChem 67530240	8I2G-FSH-FSH-PubChem 67530240-Gs/β1/γ2
16.67	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
15.79	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
15.79	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
14.81	Single	6P9X	Corticoliberin-1	6P9X-CRF₁-Corticoliberin-1-Gs/β1/γ2
14.29	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
14.29	Consensus	neurotensin_off	Orthosteric Ligand	nts1_off
14.29	Consensus	nts1_off	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
13.33	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
13.33	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
13.33	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
13.33	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
13.33	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
13.04	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
13.04	Single	8IEB	PubChem 134746894	8IEB-GPR156; GPR156-PubChem 134746894
13.04	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
12.50	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
12.50	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS; CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
12.50	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
12.50	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
12.50	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
12.50	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
12.00	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	8IED	PubChem 134746894	8IED-GPR156; GPR156-PubChem 134746894-Go/β1/γ2
11.76	Single	5UEN	DU172	5UEN-A₁-DU172
11.76	Single	7RBT	LSN3556672	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
11.76	Consensus	cck_off	Orthosteric Ligand	ccka_off
11.76	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
11.54	Single	7TYH	Calcitonin	7TYH-CT (AMY2)-Calcitonin-Gs/β1/γ2; RAMP2
11.54	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
11.11	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
11.11	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
11.11	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
11.11	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
11.11	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
11.11	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
11.11	Single	7WIG	L-054264	7WIG-SST2-L-054264-Gi1/β1/γ2
11.11	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.11	Single	8ZYT	Neurotensin-(8-13)	8ZYT-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
11.11	Single	9B9Z	MRI-1867	9B9Z-CB₁-MRI-1867
11.11	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
11.11	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
11.11	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
10.71	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
10.71	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
10.53	Single	3ZEV	Neurotensin-(7-13)	3ZEV-NTS₁-Neurotensin-(7-13)
10.53	Single	4BV0	Neurotensin-(7-13)	4BV0-NTS₁-Neurotensin-(7-13)
10.53	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
10.53	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
10.53	Single	8FMZ	Neurotensin-(8-13)	8FMZ-NTS₁-Neurotensin-(8-13)-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.53	Single	8XZI	CMF-019	8XZI-Apelin; Apelin-CMF-019-Gi1/β1/γ2
10.53	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
10.53	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
10.53	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
10.34	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
10.00	Single	7L0S	Neurotensin-(8-13)	7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
10.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
10.00	Single	7W0L	PubChem 122701908	7W0L-Apelin; Apelin-PubChem 122701908-Gi1/β1/γ2
10.00	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
10.00	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
10.00	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
10.00	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-1-Gs/β1/γ2
10.00	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
9.68	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
9.52	Single	4BUO	Neurotensin-(8-13)	4BUO-NTS₁-Neurotensin-(8-13)
9.52	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
9.52	Single	6UP7	Neurotensin-(8-13)	6UP7-NTS₁-Neurotensin-(8-13)-Arrestin2
9.52	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
9.52	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	8FN0	Neurotensin-(8-13)	8FN0-NTS₁-Neurotensin-(8-13)-SBI-553-chim(NtGi1-Go)/β1/γ2
9.52	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
9.38	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
9.38	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-1-Gs/β1/γ2
9.09	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
9.09	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
9.09	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
9.09	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
9.09	Single	7XN9	L-054522	7XN9-SST2-L-054522
9.09	Single	7Y36	PTH	7Y36-PTH1-PTH-Gs/β1/γ2
9.09	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
9.09	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
9.09	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs/β1/γ2
9.09	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.09	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
9.09	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
9.09	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
9.09	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
8.70	Single	7L0R	Neurotensin-(8-13)	7L0R-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
8.70	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
8.70	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
8.70	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
8.70	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8IEB	PubChem 134746894	8IEB-GPR156; GPR156-PubChem 134746894
8.70	Single	8IEI	PubChem 134746894	8IEI-GPR156; GPR156-PubChem 134746894
8.70	Single	8IEI	PubChem 134746894	8IEI-GPR156; GPR156-PubChem 134746894
8.70	Single	8IEP	PubChem 134746894	8IEP-GPR156; GPR156-PubChem 134746894
8.70	Single	8IEP	PubChem 134746894	8IEP-GPR156; GPR156-PubChem 134746894
8.70	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
8.70	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.70	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
8.33	Single	7W0N	Elabela	7W0N-Apelin; Apelin-Elabela-Gi1/β1/γ2
8.33	Single	7XKD	Dehydroepiandrosterone	7XKD-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
8.33	Single	7XKE	Dehydroepiandrosterone	7XKE-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
8.33	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
8.33	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
8.33	Single	9JFK	(Pen5)-Urotensin II	9JFK-UT-(Pen5)-Urotensin II-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	9KV6	TLQP21	9KV6-C3a_B-TLQP21-Go/β1/γ2
8.33	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
8.00	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
8.00	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
8.00	Single	6VN7	PACAP27	6VN7-VPAC₁-PACAP27-Gs/β1/γ2
8.00	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.00	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
8.00	Single	9LXR	LA-PTH Analog	9LXR-PTH1-LA-PTH Analog-Arrestin2
8.00	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.00	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
7.69	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2; STE2-α-factor mating pheromone-Gi1/STE4/γ2
7.69	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.69	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
7.69	Single	8IED	PubChem 134746894	8IED-GPR156; GPR156-PubChem 134746894-Go/β1/γ2
7.69	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8Y02	All-trans-Retinal	8Y02-OPN1SW-All-trans-Retinal-Gi1/β1/γ2
7.69	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
7.69	Single	9M42	A1L8O	9M42-GPR139-A1L8O-chim(Gs-CtGq)/β1/γ2
7.69	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
7.69	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
7.69	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
7.50	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
7.41	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
7.41	Single	7Y64	C5a	7Y64-C5a₁-C5a-Gi1/β1/γ2
7.41	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
7.41	Single	8XQE	Apelin-13	8XQE-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
7.41	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
7.41	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
7.41	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
7.41	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-Lysophosphatidylserine (WJS)-chim(NtGi2-G13)/β1/γ2
7.41	Consensus	pac_on	Orthosteric Ligand	pac1_on
7.41	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
7.14	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
7.14	Single	6NBF	LA-PTH Analog	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2
7.14	Single	6P9Y	PACAP27	6P9Y-PAC₁-PACAP27-Gs/β1/γ2
7.14	Single	6PWC	Neurotensin-(9-13)	6PWC-NTS₁-Neurotensin-(9-13)-Arrestin2
7.14	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
7.14	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
7.14	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
7.14	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
7.14	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
7.14	Single	8ITF	DMCHA	8ITF-TAA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8IW7	2-Phenylethylamine	8IW7-TAA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
7.14	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
7.14	Single	8Y6W	4-CMTB	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
7.14	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
7.14	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
7.14	Single	9BLW	Cagrilintide (non-acylated)	9BLW-CT (AMY1)-Cagrilintide (non-acylated)-Gs/β1/γ2; RAMP1
7.14	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
7.14	Single	9JG1	Adriforant	9JG1-H₄-Adriforant
7.14	Single	9LRC	Histamine	9LRC-H₄-Histamine
7.14	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
7.14	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
7.14	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
7.14	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
7.14	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
7.14	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
7.14	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
7.14	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
7.14	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
6.90	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
6.90	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
6.90	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2; STE2-α-factor mating pheromone-Gi1/STE4/γ2
6.90	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
6.90	Single	7EIB	Kallidin-des-Arg10	7EIB-BK₁-Kallidin-des-Arg10-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
6.90	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
6.90	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
6.90	Single	9P94	PACAP27	9P94-PAC₁-PACAP27-Gs/β1/γ2
6.90	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
6.90	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-Lysophosphatidylserine (WJS)-chim(NtGi2-G13)/β1/γ2
6.67	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
6.67	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
6.67	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
6.67	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
6.67	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
6.67	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
6.67	Single	7LD3	MIPS521	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
6.67	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
6.67	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
6.67	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
6.67	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
6.67	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
6.67	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
6.67	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
6.67	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
6.67	Single	7XKF	Dehydroepiandrosterone	7XKF-ADGRG2-Dehydroepiandrosterone-Gs/β1/γ2
6.67	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
6.67	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
6.67	Single	8KGG	Lysophosphatidylserine (WJS)	8KGG-P2Y10-Lysophosphatidylserine (WJS)-chim(NtGi2-G13)/β1/γ2
6.67	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
6.67	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
6.67	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
6.67	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
6.67	Single	8ZYU	Neurotensin-(8-13)	8ZYU-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
6.67	Single	9B9Y	Taranabant	9B9Y-CB₁-Taranabant
6.67	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
6.67	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Single	9EPR	All-trans-Retinal	9EPR-Rhodopsin-All-trans-Retinal-Gi1/β1/γ2
6.67	Single	9JED	Histamine	9JED-H₄-Histamine-PO4-Gi1/β1/γ2
6.67	Single	9JEQ	Histamine	9JEQ-H₃-Histamine-Gi1/β1/γ2
6.67	Single	9JLC	AVE 0991	9JLC-MAS1-AVE 0991-Gi1/β1/γ2
6.67	Single	9KUW	CMPD644	9KUW-Apelin; Apelin-CMPD644-Arrestin2 ; Arrestin2
6.67	Single	9L42	Histamine	9L42-H₄-Histamine-Gi1/β1/γ2
6.67	Single	9P93	VIP	9P93-PAC₁-VIP-Gs/β1/γ2
6.67	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
6.67	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
6.67	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
6.67	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
6.45	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
6.45	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
6.45	Single	8ZJE	TAK448	8ZJE-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ1
6.25	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
6.25	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
6.25	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
6.25	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
6.25	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
6.25	Single	5U09	Taranabant	5U09-CB₁-Taranabant
6.25	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
6.25	Single	6LFO	CXCL8	6LFO-CXCR2-CXCL8-Gi1/β1/γ2
6.25	Single	6LPB	PACAP27	6LPB-PAC₁-PACAP27-Gs/β1/γ1
6.25	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
6.25	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
6.25	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
6.25	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.25	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.25	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
6.25	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
6.25	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
6.25	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
6.25	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
6.25	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
6.25	Single	8IW4	Spermidine	8IW4-TAA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8IWE	Spermidine	8IWE-TAA9-Spermidine
6.25	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
6.25	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
6.25	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
6.25	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
6.25	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
6.25	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
6.25	Single	9CLW	4-CMTB	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
6.25	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
6.25	Single	9JKX	Acifran	9JKX-HCA₃-Acifran-Gi1/β1/γ2
6.25	Single	9KPE	Salicin	9KPE-TAS2R16-Salicin-Gi1/β1/γ2
6.25	Single	9LKD	PL45	9LKD-OR5V1-PL45
6.25	Single	9LLB	DOI-NBOMe	9LLB-5-HT_2A-DOI-NBOMe-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
6.25	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
6.25	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
6.25	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.25	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
6.06	Single	6WPW	ZP3780	6WPW-Glucagon-ZP3780-Gs/β1/γ2
6.06	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.06	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
5.88	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
5.88	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
5.88	Single	6FFI	MPEP	6FFI-mGlu₅-MPEP
5.88	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
5.88	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
5.88	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
5.88	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
5.88	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
5.88	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
5.88	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
5.88	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
5.88	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
5.88	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
5.88	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
5.88	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
5.88	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
5.88	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
5.88	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
5.88	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
5.88	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
5.88	Single	8K4N	PubChem 168719765	8K4N-GPR34-PubChem 168719765-Gi1/β1/γ2
5.88	Single	8PM2	DMCHA	8PM2-TA7-DMCHA-Gs/β1/γ2
5.88	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
5.88	Single	8Y01	All-trans-Retinal	8Y01-Opsin1MW-All-trans-Retinal-Gi1/β1/γ2
5.88	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
5.88	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
5.88	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4	9AXF-CaS; CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9BA0	MRI-1891	9BA0-CB₁-MRI-1891
5.88	Single	9JH3	CMF-019	9JH3-Apelin; Apelin-CMF-019-Gi1/β1/γ2
5.88	Single	9JMD	Azithromycin	9JMD-Motilin-Azithromycin-chim(Gs-CtGq)/β1/γ2
5.88	Single	9JQY	TG6-129	9JQY-EP₄-TG6-129
5.88	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
5.88	Single	9KUW	CMPD644	9KUW-Apelin; Apelin-CMPD644-Arrestin2 ; Arrestin2
5.88	Single	9KXS	EP67	9KXS-C5a₁-EP67-Go/β1/γ2
5.88	Single	9LKB	PL45	9LKB-OR5V1-PL45-chim(NtGi1-Gs)/β1
5.88	Single	9PXX	Naloxone	9PXX-μ-Naloxone-GDPβS-Gi1/β1/γ2
5.88	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
5.88	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
5.88	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
5.88	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
5.71	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
5.56	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
5.56	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
5.56	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
5.56	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
5.56	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
5.56	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
5.56	Single	4U16	N-methyl-Scopolamine	4U16-M₃-N-methyl-Scopolamine
5.56	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
5.56	Single	5T04	Neurotensin-(8-13)	5T04-NTS₁-Neurotensin-(8-13)
5.56	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
5.56	Single	5YC8	N-methyl-Scopolamine	5YC8-M₂-N-methyl-Scopolamine
5.56	Single	5ZK8	N-methyl-Scopolamine	5ZK8-M₂-N-methyl-Scopolamine
5.56	Single	5ZKC	N-methyl-Scopolamine	5ZKC-M₂-N-methyl-Scopolamine
5.56	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
5.56	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
5.56	Single	6GPS	MK0812	6GPS-CCR2-MK0812
5.56	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
5.56	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
5.56	Single	6Z4V	Neurotensin-(9-13)	6Z4V-NTS₁-Neurotensin-(9-13)
5.56	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
5.56	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
5.56	Single	7M3J	NPS-2143; PO4	7M3J-CaS; CaS-NPS-2143; PO4
5.56	Single	7NA8	Ibutamoren	7NA8-Ghrelin-Ibutamoren-Gi1/β1/γ2
5.56	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
5.56	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
5.56	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.56	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
5.56	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
5.56	Single	8IC0	CXCL8	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
5.56	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
5.56	Single	8XBG	S3E-Lysophosphatidylserine	8XBG-GPR34-S3E-Lysophosphatidylserine
5.56	Single	8Y71	A1D6F	8Y71-δ-A1D6F-BMS986187-Gi1/β1/γ2
5.56	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
5.56	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
5.56	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
5.56	Single	8ZQE	GPR15L(CT)	8ZQE-GPR15-GPR15L(CT)-Gi1/β1/γ1
5.56	Single	8ZYY	Neurotensin-(8-13)	8ZYY-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
5.56	Single	9JEA	Atropine	9JEA-M₁-Atropine
5.56	Single	9JQZ	Grapiprant	9JQZ-EP₄-Grapiprant
5.56	Single	9KFT	fMLFC	9KFT-FPR1-ALX-fMLFC-Gi1/β1/γ2
5.56	Single	9KUX	CMPD644	9KUX-Apelin; Apelin-CMPD644-Arrestin2
5.56	Single	9MET	Gp120; CD4	9MET-CXCR4-Gp120; CD4
5.56	Single	9UAZ	Atropine	9UAZ-M₁-Atropine
5.56	Consensus	a3_on	Orthosteric Ligand	a3a_on
5.56	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
5.56	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-CXCL8-Gi1/β1/γ2
5.56	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
5.56	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
5.56	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
5.56	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.56	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
5.56	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
5.56	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
5.56	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
5.26	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
5.26	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
5.26	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
5.26	Single	5N2R	PSB36	5N2R-A_2A-PSB36-Na
5.26	Single	5N2S	PSB36	5N2S-A₁-PSB36
5.26	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
5.26	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
5.26	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
5.26	Single	6GPX	MK0812	6GPX-CCR2-MK0812
5.26	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
5.26	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
5.26	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
5.26	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
5.26	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
5.26	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
5.26	Single	7EPF	NAM597	7EPF-mGlu₂-NAM597
5.26	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
5.26	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
5.26	Single	7M3J	NPS-2143; PO4	7M3J-CaS; CaS-NPS-2143; PO4
5.26	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.26	Single	7VFX	fMIFL	7VFX-FPR1-ALX-fMIFL-Gi1/β1/γ2
5.26	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
5.26	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
5.26	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
5.26	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
5.26	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
5.26	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
5.26	Single	8IZ4	Lysophosphatidylserine (TJR)	8IZ4-GPR34-Lysophosphatidylserine (TJR)-Gi1/β1/γ2
5.26	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
5.26	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
5.26	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
5.26	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
5.26	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.26	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.26	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
5.26	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.26	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
5.26	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
5.26	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
5.26	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
5.26	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
5.26	Single	9KUV	CMPD644	9KUV-Apelin-CMPD644-Arrestin2
5.26	Single	9PXY	Naloxone	9PXY-μ-Naloxone-GDPβS-Gi1/β1/γ2
5.26	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
5.26	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.26	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.26	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMIFL-Gi1/β1/γ2
5.26	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMIFL-Gi1/β1/γ2
5.26	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.26	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.26	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
5.26	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.13	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
5.13	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
5.00	Single	2YDV	NECA	2YDV-A_2A-NECA
5.00	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
5.00	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
5.00	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
5.00	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
5.00	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
5.00	Single	5G53	NECA	5G53-A_2A-NECA-Gs
5.00	Single	5V56	TC114	5V56-SMO-TC114
5.00	Single	5V57	TC114	5V57-SMO-TC114
5.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.00	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
5.00	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.00	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
5.00	Single	6DDE	DAMGO	6DDE-μ-DAMGO-Gi1/β1/γ2
5.00	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
5.00	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.00	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
5.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
5.00	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
5.00	Single	7L0P	Neurotensin-(8-13)	7L0P-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
5.00	Single	7L0Q	Neurotensin-(8-13)	7L0Q-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
5.00	Single	7P2L	4YI	7P2L-mGlu₅-4YI
5.00	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
5.00	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
5.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
5.00	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
5.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.00	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
5.00	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	7XOW	Sulfated Gastrin-(10-17)	7XOW-CCK_B-Sulfated Gastrin-(10-17)-chim(NtGi1-Gq)/β1/γ2
5.00	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
5.00	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
5.00	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
5.00	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
5.00	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
5.00	Single	8FN1	Neurotensin-(8-13)	8FN1-NTS₁-Neurotensin-(8-13)-chim(NtGi1-Go)/β1/γ2
5.00	Single	8HPT	C5a (C-terminal peptide)	8HPT-C5a₁-C5a (C-terminal peptide)-Go/β1/γ2
5.00	Single	8HQC	C5a	8HQC-C5a₁-C5a-Go/β1/γ2
5.00	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
5.00	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
5.00	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
5.00	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
5.00	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.00	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.00	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
5.00	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
5.00	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.00	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.00	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
5.00	Single	8XBI	PubChem 162656636	8XBI-GPR34-PubChem 162656636
5.00	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
5.00	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
5.00	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
5.00	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
5.00	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
5.00	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9E9S	PGD2	9E9S-DP₁-PGD2-Gs/β1/γ1
5.00	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
5.00	Single	9JCL	ADP	9JCL-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
5.00	Single	9KUX	CMPD644	9KUX-Apelin; Apelin-CMPD644-Arrestin2
5.00	Single	9MEN	Gp120 (V3 loop)	9MEN-CXCR4-Gp120 (V3 loop)
5.00	Single	9PY3	Loperamide	9PY3-μ-Loperamide-GDPβS-Gi1/β1/γ2
5.00	Single	9UCP	Iperoxo	9UCP-M₁-Iperoxo-G11(CT)
5.00	Single	9UY3	Anamorelin	9UY3-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9YDV	MRS2905	9YDV-P2Y₁₄-MRS2905-Gi1/β1/γ2
5.00	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
5.00	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.00	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.00	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
5.00	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
5.00	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
5.00	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
5.00	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
5.00	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.00	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
4.76	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
4.76	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
4.76	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.76	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
4.76	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
4.76	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
4.76	Single	4XEE	Neurotensin-(8-13)	4XEE-NTS₁-Neurotensin-(8-13)
4.76	Single	4XES	Neurotensin-(8-13)	4XES-NTS₁-Neurotensin-(8-13)
4.76	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
4.76	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
4.76	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
4.76	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
4.76	Single	6OS0	Angiotensin II	6OS0-AT₁-Angiotensin II
4.76	Single	6OS2	TRV026	6OS2-AT₁-TRV026
4.76	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
4.76	Single	6YVR	Neurotensin-(6-13)	6YVR-NTS₁-Neurotensin-(6-13)
4.76	Single	7EPE	NAM563	7EPE-mGlu₂-NAM563
4.76	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.76	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
4.76	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7W0L	PubChem 122701908	7W0L-Apelin; Apelin-PubChem 122701908-Gi1/β1/γ2
4.76	Single	7W0N	Elabela	7W0N-Apelin; Apelin-Elabela-Gi1/β1/γ2
4.76	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
4.76	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
4.76	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8ID9	Icosapent	8ID9-FFA4-Icosapent-Gi1/β1/γ2
4.76	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
4.76	Single	8JJP	Chemerin-9	8JJP-CML2-Chemerin-9-Gi1/β1/γ2
4.76	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
4.76	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
4.76	Single	8JWY	2-118	8JWY-A_2A-2-118
4.76	Single	8JWZ	Etrumadenant	8JWZ-A_2A-Etrumadenant-Na
4.76	Single	8T3Q	Doconexent	8T3Q-FFA4-Doconexent-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
4.76	Single	8XQJ	JN241	8XQJ-Apelin; Apelin-JN241
4.76	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
4.76	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
4.76	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
4.76	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
4.76	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
4.76	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
4.76	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
4.76	Single	9ECJ	S-geranylgeranyl-L-glutathione	9ECJ-P2Y8-S-geranylgeranyl-L-glutathione-G13/β1/γ2
4.76	Single	9EK0	Iperoxo	9EK0-M₅-Iperoxo-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	9L3W	Chemerin	9L3W-CML1-Chemerin-Gi1/β1/γ2
4.76	Single	9VIF	Neuropeptide-VF	9VIF-NPFF1-Neuropeptide-VF-Gi1/β1/γ2
4.76	Single	9WXM	GPR15L(CT)	9WXM-GPR15-GPR15L(CT)-Gi3/β1/γ2
4.76	Single	9YDQ	DADLE	9YDQ-δ-DADLE-MIPS3614-chim(NtGi1L-Gs-CtGi1)/β1/γ2
4.76	Single	9YDU	UDP-Glucose	9YDU-P2Y₁₄-UDP-Glucose-Gi1/β1/γ2
4.76	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
4.76	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
4.76	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
4.76	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
4.76	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
4.76	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
4.76	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
4.76	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.76	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
4.76	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
4.76	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
4.76	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.76	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.76	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
4.76	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-(8-13)-Gi1/β1/γ1
4.76	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
4.55	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.55	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
4.55	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
4.55	Single	6DDF	DAMGO	6DDF-μ-DAMGO-Gi1/β1/γ2
4.55	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.55	Single	7EZC	UK-432097	7EZC-A_2A-UK-432097
4.55	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.55	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
4.55	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
4.55	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
4.55	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
4.55	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
4.55	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
4.55	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
4.55	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
4.55	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
4.55	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
4.55	Single	8JPF	Neurotensin-(8-13)	8JPF-NTS₁-Neurotensin-(8-13)-SBI-553
4.55	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
4.55	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
4.55	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8XBE	S3E-Lysophosphatidylserine	8XBE-GPR34-S3E-Lysophosphatidylserine-Gi1/β1/γ1
4.55	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
4.55	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
4.55	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
4.55	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
4.55	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
4.55	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
4.55	Single	9CGJ	C6-Quino	9CGJ-δ-C6-Quino-Gi1/β1/γ2
4.55	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
4.55	Single	9IZF	LPA	9IZF-LPA₁-LPA-Gi1/β1/γ2
4.55	Single	9J0B	UDP-Glucose	9J0B-P2Y₁₄-UDP-Glucose-Gi1/β1/γ2
4.55	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	9KUG	EP67	9KUG-C5a₁-EP67-Go/β1/γ2
4.55	Single	9KV8	TLQP21	9KV8-C3a_B-TLQP21-Go/β1/γ2
4.55	Single	9UYH	Chemerin-9	9UYH-CML2-Chemerin-9-Arrestin2
4.55	Single	9UYM	Chemerin-9	9UYM-CML2-Chemerin-9-chim(Arrestin3-CtArrestin2)
4.55	Single	9VI9	RFRP-3	9VI9-NPFF1-RFRP-3-Gi1/β1/γ2
4.55	Single	9YDP	DADLE	9YDP-δ-DADLE-chim(NtGi1L-Gs-CtGi1)/β1/γ2
4.55	Single	9YDR	DADLE	9YDR-δ-DADLE-MIPS3983-chim(NtGi1L-Gs-CtGi1)/β1/γ2
4.55	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
4.55	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
4.55	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.55	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.55	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
4.55	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.55	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
4.35	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
4.35	Single	5VBL	AMG3054	5VBL-Apelin-AMG3054
4.35	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
4.35	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
4.35	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
4.35	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
4.35	Single	6PT3	DPI-287	6PT3-δ-DPI-287
4.35	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
4.35	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
4.35	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.35	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
4.35	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8SAI	Lysophosphatidylserine (S12)	8SAI-GPR34-Lysophosphatidylserine (S12)-Gi1/β1/γ2
4.35	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
4.35	Single	8XQJ	JN241	8XQJ-Apelin; Apelin-JN241
4.35	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
4.35	Single	8XZF	WN561	8XZF-Apelin; Apelin-WN561-Gi1/β1/γ2
4.35	Single	8Z74	JN241-9	8Z74-Apelin; Apelin-JN241-9
4.35	Single	8Z74	JN241-9	8Z74-Apelin; Apelin-JN241-9
4.35	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
4.35	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
4.35	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
4.35	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	9KX6	C5a-des-Arg	9KX6-C5a₁-C5a-des-Arg-Go/β1/γ2
4.35	Single	9KZ8	EP67	9KZ8-C3a_B-EP67-Go/β1/γ2
4.35	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
4.35	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
4.35	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
4.35	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.35	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
4.17	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
4.17	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
4.17	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
4.17	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
4.17	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
4.17	Single	7NA7	Ghrelin	7NA7-Ghrelin-Ghrelin-Gi1/β1/γ2
4.17	Single	7QA8	Antagonist Peptide	7QA8-STE2; STE2-Antagonist Peptide
4.17	Single	7QA8	Antagonist Peptide	7QA8-STE2; STE2-Antagonist Peptide
4.17	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
4.17	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
4.17	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
4.17	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
4.17	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.17	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
4.17	Single	8IZB	Lysophosphatidylserine (UBL)	8IZB-GPR174-Lysophosphatidylserine (UBL)-Gs/β1/γ2
4.17	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
4.17	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
4.17	Single	8WKY	PG-934	8WKY-MC₄-PG-934
4.17	Single	8XBH	PubChem 162656636	8XBH-GPR34-PubChem 162656636-Gi1/β1/γ2
4.17	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
4.17	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
4.17	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
4.17	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
4.17	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
4.17	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
4.17	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
4.17	Single	9KWG	C5a	9KWG-C5a₁-C5a-Go/β1/γ2
4.17	Single	9L3Y	Chemerin	9L3Y-CML2-Chemerin-Gi1/β1/γ2
4.17	Single	9MEJ	Gp120	9MEJ-CXCR4-Gp120
4.17	Single	9UMR	C5a-pep	9UMR-C5a₁-C5a-pep-Go/β1/γ2
4.17	Single	9UYJ	Chemerin-9	9UYJ-CML2-Chemerin-9-Arrestin2
4.17	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
4.17	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
4.17	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.17	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.17	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
4.17	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.17	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.17	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.17	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
4.17	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
4.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
4.00	Single	6DO1	(Sar1,Ile8)-Angiotensin II	6DO1-AT₁-(Sar1,Ile8)-Angiotensin II
4.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
4.00	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
4.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
4.00	Single	7F1Q	CCL3	7F1Q-CCR5-CCL3-Gi1/β1/γ2
4.00	Single	7PIV	Afamelanotide	7PIV-MC₄-Afamelanotide-Gs/β1/γ2
4.00	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
4.00	Single	7VBI	Tirzepatide (non-acylated)	7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
4.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
4.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
4.00	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
4.00	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
4.00	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
4.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
4.00	Single	8JZZ	C5a-des-Arg	8JZZ-C5a₁-C5a-des-Arg-Go/β1/γ2
4.00	Single	8K6O	Neuropeptide-Y	8K6O-Y₁-Neuropeptide-Y-Gi2/β1/γ1
4.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
4.00	Single	8WSS	MCH	8WSS-MCH1-MCH-Gi1/β1/γ1
4.00	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
4.00	Single	8Z7J	JN241-9	8Z7J-Apelin-JN241-9-Gi1/β1/γ2
4.00	Single	9IQR	Muscarinic toxin 3	9IQR-α_2a-Muscarinic toxin 3
4.00	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
4.00	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
4.00	Single	9L60	Dynorphin	9L60-κ-Dynorphin-MPAM-15-Gi1/β1/γ2
4.00	Single	9ME1	CXCL12	9ME1-CXCR4-CXCL12
4.00	Single	9UMX	EP54	9UMX-C5a₁-EP54-Go/β1/γ2
4.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
4.00	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
4.00	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-Ibutamoren-Gi1/β1/γ2
4.00	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-Ibutamoren-Gi1/β1/γ2
4.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-Gi1/β1/γ2 7NA8-Ghrelin-Ibutamoren-Gi1/β1/γ2
4.00	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.00	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
4.00	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
3.85	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
3.85	Single	6MEO	Gp160; CD4	6MEO-CCR5-Gp160; CD4
3.85	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
3.85	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.85	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
3.85	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
3.85	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
3.85	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
3.85	Single	8K6N	Neuropeptide-Y	8K6N-Y₂-Neuropeptide-Y-Gi2/β1/γ1
3.85	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
3.85	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
3.85	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
3.85	Single	8XZG	Apelin-13	8XZG-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
3.85	Single	8XZH	MM07	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2
3.85	Single	9B54	VIP36	9B54-CB₁-VIP36-Gi1/β1/γ2
3.85	Single	9B5Y	LA-PTH Analog	9B5Y-PTH1-LA-PTH Analog-chim(NtGi1-Gq)/β1/γ2
3.85	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
3.85	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
3.85	Single	9MEU	CXCL12	9MEU-CXCR4-CXCL12
3.85	Single	9UYI	Chemerin-9	9UYI-CML2-Chemerin-9-Arrestin2
3.85	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
3.85	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
3.85	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
3.85	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
3.85	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-14-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.85	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.85	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
3.85	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
3.85	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
3.70	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
3.70	Single	6M1I	PACAP27	6M1I-PAC₁-PACAP27-Gs/β1/γ2
3.70	Single	6MET	Gp160; CD4	6MET-CCR5-Gp160; CD4
3.70	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
3.70	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
3.70	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7F6G	(Sar1)-Angiotensin II	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
3.70	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
3.70	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
3.70	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
3.70	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
3.70	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	8WST	MCH	8WST-MCH2-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
3.70	Single	8XZJ	WN353	8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2
3.70	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
3.70	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
3.70	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	9BLC	Cagrilintide (non-acylated)	9BLC-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
3.70	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
3.70	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
3.70	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin; Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
3.70	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin; Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
3.70	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
3.70	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
3.70	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
3.70	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-(Sar1)-Angiotensin II-Gq/β1/γ2
3.70	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
3.70	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
3.70	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
3.70	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
3.70	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
3.70	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
3.70	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
3.70	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
3.57	Single	5YQZ	NNC1702	5YQZ-Glucagon-NNC1702
3.57	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
3.57	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
3.57	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
3.57	Single	7F9Y	Ghrelin	7F9Y-Ghrelin-Ghrelin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
3.57	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2; STE2-α-factor mating pheromone
3.57	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
3.57	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.57	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.57	Single	7XV3	Lysophosphatidylserine (WJS)	7XV3-GPR174-Lysophosphatidylserine (WJS)-chim(NtGi1-Gs)/β1/γ2
3.57	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
3.57	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.57	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.57	Single	8HK5	C5a	8HK5-C5a₁-C5a-Gi1/β1/γ2
3.57	Single	8IA2	C5a	8IA2-C5a₁-C5a-Go/β1/γ2
3.57	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
3.57	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
3.57	Single	8YG4	LA-PTH Analog	8YG4-PTH1-LA-PTH Analog-chim(NtGi1-Gs)/β1/γ2
3.57	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.57	Single	8ZRT	Endothelin-1	8ZRT-ET_B-Endothelin-1
3.57	Single	9E2A	GLP-1	9E2A-GLP-1-GLP-1-Gs/β1/γ2
3.57	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
3.57	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
3.57	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.57	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin; Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin; Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin; Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin; Apelin-Apelin-13-Gi1/β1/γ2
3.57	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
3.57	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.45	Single	4XT3	CX3CL1	4XT3-US28-CX3CL1
3.45	Single	6FJ3	PTH	6FJ3-PTH1-PTH
3.45	Single	6NBI	LA-PTH Analog	6NBI-PTH1-LA-PTH Analog-Gs/β1/γ2
3.45	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
3.45	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2; STE2-α-factor mating pheromone
3.45	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
3.45	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
3.45	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
3.45	Single	7VAB	Tirzepatide (non-acylated)	7VAB-GIP-Tirzepatide (non-acylated)-chim(NtGi1-Gs)/β1/γ2
3.45	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.45	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.45	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
3.45	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
3.45	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
3.45	Single	9BLB	Cagrilintide (non-acylated)	9BLB-CT-Cagrilintide (non-acylated)-Gs/β1/γ2
3.45	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
3.45	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
3.45	Single	9P92	VIP	9P92-PAC₁-VIP-Gs/β1/γ2
3.45	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-CCL3-Gi1/β1/γ2
3.45	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
3.45	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-C5a-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a-Gi1/β1/γ2 7Y64-C5a₁-C5a-Gi1/β1/γ2
3.45	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
3.45	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
3.45	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.45	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.45	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
3.45	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.45	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.45	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
3.45	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
3.45	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.33	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
3.33	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
3.33	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2; STE2-α-factor mating pheromone
3.33	Single	7S1M	Exendin-4-D-Ala	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2
3.33	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
3.33	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
3.33	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.33	Single	8FU6	ZP3780	8FU6-Glucagon-ZP3780-Gs/β1/γ2
3.33	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
3.33	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
3.33	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
3.33	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
3.33	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
3.33	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
3.33	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
3.33	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
3.33	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.33	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.33	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
3.33	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
3.33	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
3.33	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.33	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.33	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
3.33	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
3.33	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
3.23	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
3.23	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
3.23	Single	6NBH	LA-PTH Analog	6NBH-PTH1-LA-PTH Analog-Gs/β1/γ2
3.23	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
3.23	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
3.23	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
3.23	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2; STE2-α-factor mating pheromone
3.23	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.23	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
3.23	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
3.23	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
3.23	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
3.23	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.23	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.23	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
3.23	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
3.23	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
3.23	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.23	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.23	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
3.23	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.23	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
3.23	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
3.12	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
3.12	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
3.12	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
3.12	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-CCL3-Gi1/β1/γ2
3.12	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.12	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.12	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
3.12	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
3.12	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
3.12	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
3.03	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
3.03	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.03	Single	8FLU	LA-PTH Analog	8FLU-PTH1-LA-PTH Analog-Gs/β1/γ2
3.03	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
3.03	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
3.03	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.03	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
2.94	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
2.94	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.94	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
2.94	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
2.94	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Exendin-4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Tirzepatide (non-acylated)-Gs/β1/γ2
2.94	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
2.94	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-LA-PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-PTH-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
2.86	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.86	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
2.86	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
2.86	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
2.86	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
2.78	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.78	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
2.70	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.70	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.63	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
2.63	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
2.33	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

PDB Summary
PDB	9MBC
Class	C
SubFamily	Aminoacid
Type	Metabotropic glutamate
SubType	mGlu8; mGlu8
Species	Homo Sapiens
Ligand	DCPG
Other Ligand(s)	AZ12216052
Protein Partners	-
PDB Resolution	2.97
Date	2025-10-01
D.O.I.	doi.org/10.1016/j.molcel.2025.08.019

Net Summary
I_min	2.61
Number of Linked Nodes	1411
Number of Links	1701
Number of Hubs	262
Number of Links mediated by Hubs	941
Number of Communities	51
Number of Nodes involved in Communities	374
Number of Links involved in Communities	516

Path Summary
Number Of Nodes in MetaPath	125
Number Of Links MetaPath	124
Number of Shortest Paths	6632735
Length Of Smallest Path	3
Average Path Length	45.5151
Length of Longest Path	99
Minimum Path Strength	1.345
Average Path Strength	5.92583
Maximum Path Strength	18.615
Minimum Path Correlation	0.72
Average Path Correlation	0.998618
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.08333
Average % Of Corr. Nodes	54.6092
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.8375
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • cell surface receptor signaling pathway • signaling • biological regulation • glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • multicellular organismal process • sensory perception of light stimulus • system process • sensory perception • nervous system process • visual perception • trans-synaptic signaling • regulation of signaling • modulation of chemical synaptic transmission • synaptic transmission, glutamatergic • cell-cell signaling • regulation of synaptic transmission, glutamatergic • chemical synaptic transmission • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • regulation of cell communication • cell periphery • cellular anatomical structure • plasma membrane • membrane
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Type 1 solute binding protein-like
SCOP2	Family Identifier	• Type 1 solute binding protein-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	HVG
PDB Residues	L:L:?1 M:M:?1
Environment Details	Open EMBL-EBI Page
Code	HVG
Name	4-[(S)-amino(carboxy)methyl]benzene-1,2-dicarboxylic acid
Synonyms	(S)-3,4-Dicarboxyphenylglycine (DCPG)
Identifier
Formula	C10 H9 N O6
Molecular Weight	239.182
SMILES
PubChem	16062593
Formal Charge	0
Total Atoms	26
Total Chiral Atoms	1
Total Bonds	26
Total Aromatic Bonds	6


Code	_W_
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	_W_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


Code	_X_
PDB Residues	X:X:?1
Environment Details	Open EMBL-EBI Page
Code	_X_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O00222
Sequence	>9MBC_Chain_R H S I R V D G D I I L G G L F P V H A K G E R G V P C G E L K K E K G I H R L E A M L Y A I D Q I N K D P D L L S N I T L G V R I L D T C S R D T Y A L E Q S L T F V Q A L P D K I S G V I G A A A S S V S I M V A N I L R L F K I P Q I S Y A S T A P E L S D N T R Y D F F S R V V P P D S Y Q A Q A M V D I V T A L G W N Y V S T L A S E G N Y G E S G V E A F T Q I S R E I G G V C I A Q S Q K I P R E P R P G E F E K I I K R L L E T P N A R A V I M F A N E D D I R R I L E A A K K L N Q S G H F L W I G S D S W G S K I A P V Y Q Q E E I A E G A V T I L P K R A S I D G F D R Y F R S R T L A N N R R N V W F A E F W E E N F G C K L I K K C T G L E R I A R D S S Y E Q E G K V Q F V I D A V Y S M A Y A L H N M H K D L C P G Y I G L C P R M S T I D G K E L L G Y I R A V N F N G S A G T P V T F N E N G D A P G R Y D I F Q Y Q I T N K S T E Y K V I G H W T N Q L H L K V E D M Q W A T H P A S V C S L P C K P G E R K K T V K G V P C C W H C E R C E G Y N Y Q V D E L S C E L C P L D Q R P N M N R T G C Q L I P I I K L E W H S P W A V V P V F V A I L G I I A T T F V I V T F V R Y N D T P I V R A S G R E L S Y V L L T G I F L C Y S I T F L M I A A P D T I I C S F R R V F L G L G M C F S Y A A L P A S Q L V I T F S L I S V Q L L G V F V W F V V D P P H I I I D Y G E Q R T L D P E K A R G V L K C D I S D L S L I C S L G Y S I L L M V T C T V T F N E A K P I G F T M Y T T C I I W L A F I P I F F G T A Q S A E K M Y I Q T T T L T V S M S L S A S V S L G M L Y M P K V Y I I I F H P E Q N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	O00222
Sequence	>9MBC_Chain_S H S I R V D G D I I L G G L F P V H A K G E R G V P C G E L K K E K G I H R L E A M L Y A I D Q I N K D P D L L S N I T L G V R I L D T C S R D T Y A L E Q S L T F V Q A L P D K I S G V I G A A A S S V S I M V A N I L R L F K I P Q I S Y A S T A P E L S D N T R Y D F F S R V V P P D S Y Q A Q A M V D I V T A L G W N Y V S T L A S E G N Y G E S G V E A F T Q I S R E I G G V C I A Q S Q K I P R E P R P G E F E K I I K R L L E T P N A R A V I M F A N E D D I R R I L E A A K K L N Q S G H F L W I G S D S W G S K I A P V Y Q Q E E I A E G A V T I L P K R A S I D G F D R Y F R S R T L A N N R R N V W F A E F W E E N F G C K L I K K C T G L E R I A R D S S Y E Q E G K V Q F V I D A V Y S M A Y A L H N M H K D L C P G Y I G L C P R M S T I D G K E L L G Y I R A V N F N G S A G T P V T F N E N G D A P G R Y D I F Q Y Q I T N K S T E Y K V I G H W T N Q L H L K V E D M Q W A T H P A S V C S L P C K P G E R K K T V K G V P C C W H C E R C E G Y N Y Q V D E L S C E L C P L D Q R P N M N R T G C Q L I P I I K L E W H S P W A V V P V F V A I L G I I A T T F V I V T F V R Y N D T P I V R A S G R E L S Y V L L T G I F L C Y S I T F L M I A A P D T I I C S F R R V F L G L G M C F S Y A A L P A S Q L V I T F S L I S V Q L L G V F V W F V V D P P H I I I D Y G E Q R T L D P E K A R G V L K C D I S D L S L I C S L G Y S I L L M V T C T V T F N E A K P I G F T M Y T T C I I W L A F I P I F F G T A Q S A E K M Y I Q T T T L T V S M S L S A S V S L G M L Y M P K V Y I I I F H P E Q N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9MBA	C	Aminoacid	Metabotropic glutamate	mGlu8; mGlu8	Homo sapiens	Glutamate	-	Arrestin2 ; Arrestin2	3.14	2025-10-01	doi.org/10.1016/j.molcel.2025.08.019
	9MBB	C	Aminoacid	Metabotropic glutamate	mGlu8; mGlu8	Homo sapiens	LY341495	-	-	3.25	2025-10-01	doi.org/10.1016/j.molcel.2025.08.019
	9MBC	C	Aminoacid	Metabotropic glutamate	mGlu8; mGlu8	Homo sapiens	DCPG	AZ12216052	-	2.97	2025-10-01	doi.org/10.1016/j.molcel.2025.08.019
	9MBD	C	Aminoacid	Metabotropic glutamate	mGlu8; mGlu8	Homo sapiens	-	-	-	3.32	2025-10-01	doi.org/10.1016/j.molcel.2025.08.019

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