psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.33	4.4588	No	No	0	7	4
2	G.HN.39	b.b5x5	3.26779	No	Yes	0	5	5
3	G.HN.40	b.b5x2	7.06171	No	Yes	0	7	7
4	G.HN.40	b.b5x3	3.42585	No	Yes	0	7	9
5	G.HN.43	b.b5x3	5.73974	No	Yes	0	9	9
6	G.HN.44	b.b5x3	9.89707	No	Yes	0	6	9
7	G.HN.47	b.b4x2	3.72702	No	Yes	0	6	8
8	G.HN.50	b.b4x2	6.09704	No	Yes	0	5	8
9	G.S1.01	G.S3.02	7.03526	No	No	0	6	4
10	G.S1.01	G.S3.04	9.34746	No	Yes	0	6	6
11	G.S1.02	G.S1.04	2.75032	Yes	No	7	5	7
12	G.S1.02	G.S3.01	3.12756	Yes	Yes	7	5	4
13	G.S1.02	G.S3.03	8.03154	Yes	Yes	7	5	7
14	G.S1.02	G.h2s4.05	5.13721	Yes	No	0	5	7
15	G.H5.11	G.S1.02	4.73958	No	Yes	7	8	5
16	G.S1.03	G.S3.06	6.67895	No	Yes	0	9	5
17	G.S1.04	G.S3.03	3.63114	No	Yes	7	7	7
18	G.S1.04	G.S4.03	4.70943	No	No	0	7	7
19	G.S1.05	G.S1.07	5.97496	No	No	0	9	9
20	G.S1.05	G.h2s4.01	9.64509	No	Yes	0	9	9
21	G.S1.05	G.S4.02	2.69879	No	No	0	9	8
22	G.H1.01	G.S1.06	5.32884	Yes	No	17	9	8
23	G.S1.06	G.S3.05	5.70488	No	No	0	8	7
24	G.S1.06	G.S3.07	3.54972	No	Yes	17	8	9
25	G.S1.07	G.S4.04	2.80587	No	Yes	0	9	9
26	G.H3.12	G.S1.07	4.37142	No	No	0	8	9
27	G.H1.01	G.s1h1.01	3.3463	Yes	No	0	9	9
28	G.H3.01	G.s1h1.04	4.39072	Yes	No	0	9	9
29	G.H1.01	G.S3.07	6.55314	Yes	Yes	17	9	9
30	G.H1.04	G.S4.05	3.56172	No	No	0	7	7
31	G.H1.04	G.S5.05	3.30576	No	Yes	0	7	9
32	G.H1.04	G.S5.07	4.10736	No	Yes	0	7	9
33	G.H1.07	G.s6h5.05	3.04776	No	No	0	9	9
34	G.H1.07	G.H5.03	7.23441	No	Yes	0	9	8
35	G.H1.08	G.S2.06	8.01253	No	No	0	8	9
36	G.H1.08	G.H5.04	2.80226	No	No	0	8	7
37	G.hfs2.06	b.l7x4	2.7121	No	Yes	0	7	9
38	G.hfs2.07	b.l7x4	4.36227	No	Yes	0	9	9
39	G.S2.01	G.S3.08	3.50204	No	No	0	9	9
40	G.S2.01	b.l5x5	6.28297	No	Yes	1	9	9
41	G.S2.01	b.l7x2	2.92936	No	Yes	1	9	9
42	G.S2.03	G.S3.06	7.32089	Yes	Yes	1	9	5
43	G.S2.03	b.l5x5	2.6859	Yes	Yes	1	9	9
44	G.S2.05	G.S3.04	9.5005	Yes	Yes	1	3	6
45	G.S2.06	G.S3.03	14.0872	No	Yes	0	9	7
46	G.S2.06	G.S3.05	3.40933	No	No	0	9	7
47	G.S2.07	G.S3.02	8.06273	No	No	0	3	4
48	G.S2.08	G.s2s3.01	11.1877	Yes	No	7	5	4
49	G.H5.04	G.S2.08	8.93689	No	Yes	0	7	5
50	G.H5.05	G.S2.08	4.04644	No	Yes	7	5	5
51	G.H5.08	G.S2.08	6.3147	Yes	Yes	7	8	5
52	G.H5.05	G.s2s3.01	3.33987	No	No	7	5	4
53	G.H5.08	G.s2s3.01	6.88178	Yes	No	7	8	4
54	G.S3.01	G.S3.03	7.38477	Yes	Yes	7	4	7
55	G.H5.08	G.S3.01	4.17444	Yes	Yes	7	8	4
56	G.H5.11	G.S3.03	4.61098	No	Yes	7	8	7
57	G.S3.04	G.S3.06	5.74735	Yes	Yes	1	6	5
58	G.S3.06	G.h2s4.01	4.16731	Yes	Yes	1	5	9
59	G.S3.06	b.l5x5	13.3397	Yes	Yes	1	5	9
60	G.H2.07	G.S3.08	7.15808	Yes	No	0	9	9
61	G.H2.02	G.s3h2.03	2.88446	No	Yes	1	8	9
62	G.H2.07	G.s3h2.03	5.17672	Yes	Yes	1	9	9
63	G.s3h2.03	b.l9x6	4.04216	Yes	Yes	1	9	8
64	G.H2.02	b.l9x6	4.70197	No	Yes	1	8	8
65	G.H2.03	G.H2.05	8.1626	No	No	1	9	8
66	G.H2.03	b.l13x6	4.12673	No	Yes	1	9	9
67	G.H2.04	G.H2.07	3.50966	No	Yes	0	9	9
68	G.H2.04	G.H3.08	3.40543	No	No	0	9	9
69	G.H2.04	G.H3.11	3.95124	No	No	0	9	7
70	G.H2.06	b.l9x6	3.74598	Yes	Yes	1	9	8
71	G.H2.06	b.b14x1	7.6586	Yes	No	1	9	8
72	G.H2.06	b.l15x1	4.60774	Yes	Yes	1	9	7
73	G.H2.06	b.l17x6	7.55967	Yes	Yes	1	9	9
74	G.H2.06	b.b18x1	3.64894	Yes	No	0	9	9
75	G.H2.07	G.h2s4.01	3.62522	Yes	Yes	1	9	9
76	G.H2.07	b.l7x2	2.99016	Yes	Yes	1	9	9
77	G.H2.07	b.l9x6	3.02769	Yes	Yes	1	9	8
78	G.H2.08	G.H3.18	4.88867	No	Yes	0	8	9
79	G.H2.09	G.H2.10	2.69999	Yes	No	1	8	7
80	G.H2.09	G.H3.17	8.32284	Yes	Yes	1	8	5
81	G.H2.09	b.b2x1	6.56319	Yes	Yes	1	8	8
82	G.H2.09	b.l28x1	5.75672	Yes	Yes	1	8	9
83	G.H2.10	b.b2x1	4.77578	No	Yes	1	7	8
84	G.H2.10	b.l3x1	2.72874	No	No	1	7	9
85	G.h2s4.01	b.l5x5	9.5738	Yes	Yes	1	9	9
86	G.H3.17	G.h2s4.02	8.17478	Yes	No	0	5	7
87	G.h2s4.02	b.l1x6	5.984	No	No	0	7	9
88	G.H3.18	G.S4.02	7.38963	Yes	No	16	9	8
89	G.S4.02	G.h3s5.03	3.31096	No	No	16	8	7
90	G.S4.04	G.S4.06	2.80682	Yes	No	0	9	7
91	G.H3.08	G.S4.04	5.35879	No	Yes	0	9	9
92	G.H3.09	G.S4.04	13.084	Yes	Yes	6	9	9
93	G.S4.04	G.S5.04	2.88926	Yes	Yes	6	9	9
94	G.H3.05	G.S4.06	2.6783	No	No	0	9	7
95	G.H4.15	G.S4.06	6.41331	Yes	No	0	8	7
96	G.S4.07	G.s4h3.03	3.49063	No	No	0	8	8
97	G.S5.06	G.s4h3.01	7.56302	No	No	0	8	7
98	G.HG.04	G.s4h3.01	8.65347	Yes	No	0	9	7
99	G.H4.11	G.s4h3.01	3.21011	No	No	0	7	7
100	G.s4h3.02	G.s5hg.01	5.32183	No	No	0	9	9
101	G.HG.03	G.s4h3.02	5.17961	No	No	0	6	9
102	G.HG.07	G.s4h3.02	3.27826	No	No	0	9	9
103	G.H3.01	G.s4h3.03	9.61099	Yes	No	0	9	8
104	G.HG.04	G.s4h3.04	4.29363	Yes	Yes	9	9	8
105	G.hgh4.01	G.s4h3.04	3.58006	No	Yes	0	6	8
106	G.HG.07	G.s4h3.05	5.91733	No	Yes	9	9	9
107	G.H3.01	G.s4h3.06	4.97129	Yes	No	0	9	8
108	G.H3.06	G.hgh4.02	4.53933	No	Yes	0	6	7
109	G.H3.06	G.H4.15	4.96955	No	Yes	0	6	8
110	G.H3.06	G.h4s6.01	2.92694	No	No	0	6	4
111	G.H3.09	G.S5.02	3.8766	Yes	No	6	9	6
112	G.H3.09	G.S5.04	2.91099	Yes	Yes	6	9	9
113	G.H3.09	G.h4s6.01	3.83559	Yes	No	0	9	4
114	G.H3.09	G.S6.01	3.17452	Yes	No	0	9	5
115	G.H3.10	G.H3.14	5.89297	No	No	0	5	8
116	G.H3.13	G.S5.02	2.77505	Yes	No	6	5	6
117	G.H3.13	G.h4s6.02	3.45905	Yes	Yes	6	5	8
118	G.H3.13	G.h4s6.11	4.72141	Yes	Yes	6	5	7
119	G.H3.14	G.h4s6.03	8.1895	No	No	0	8	5
120	G.H3.15	G.H3.17	4.60159	No	Yes	0	8	5
121	G.H3.15	G.H3.18	4.34416	No	Yes	0	8	9
122	G.H3.16	G.H3.17	11.8623	No	Yes	0	4	5
123	G.H3.17	b.l25x6	3.84918	Yes	No	1	5	8
124	G.H3.17	b.l28x1	3.36573	Yes	Yes	1	5	9
125	G.H3.18	G.h3s5.03	5.25782	Yes	No	16	9	7
126	G.h3s5.01	G.h3s5.02	3.62966	No	No	0	3	4
127	G.h3s5.01	G.h4s6.04	4.30375	No	No	0	3	4
128	G.S5.01	G.S6.02	3.4148	No	Yes	0	7	7
129	G.H5.14	G.S5.01	5.1774	No	No	0	7	7
130	G.S5.02	G.h4s6.11	4.03934	No	Yes	6	6	7
131	G.S5.03	G.S5.05	3.01056	No	Yes	0	8	9
132	G.H5.10	G.S5.03	3.29146	No	No	0	6	8
133	G.S5.04	G.S5.06	3.72995	Yes	No	0	9	8
134	G.H4.15	G.S5.04	3.64731	Yes	Yes	6	8	9
135	G.S5.04	G.S6.03	5.75933	Yes	No	6	9	5
136	G.S5.05	G.S6.04	4.22055	Yes	No	12	9	9
137	G.S5.05	G.s6h5.01	4.82437	Yes	No	12	9	9
138	G.H5.03	G.S5.05	3.17333	Yes	Yes	12	8	9
139	G.S5.06	G.S6.05	7.91361	No	No	0	8	4
140	G.S5.07	G.s5hg.01	2.71054	Yes	No	0	9	9
141	G.S5.07	G.s6h5.01	5.85442	Yes	No	0	9	9
142	G.H4.03	G.HG.01	6.40887	Yes	No	0	4	5
143	G.HG.01	G.s6h5.02	3.49126	No	No	0	5	7
144	G.HG.04	G.HG.08	5.14396	Yes	No	9	9	6
145	G.H4.03	G.HG.04	3.42394	Yes	Yes	0	4	9
146	G.HG.13	G.HG.14	3.17095	Yes	No	0	7	5
147	G.HG.14	G.HG.16	3.04682	No	No	0	5	4
148	G.hgh4.01	G.hgh4.02	7.87889	No	Yes	0	6	7
149	G.H4.10	G.hgh4.02	5.87463	No	Yes	18	6	7
150	G.H4.14	G.hgh4.02	8.58918	No	Yes	18	5	7
151	G.hgh4.05	G.hgh4.07	5.79281	Yes	No	0	7	7
152	G.H4.05	G.hgh4.05	3.6338	No	Yes	0	4	7
153	G.H4.10	G.hgh4.05	15.1532	No	Yes	0	6	7
154	G.H4.02	G.hgh4.08	3.67925	No	No	19	5	3
155	G.H4.05	G.hgh4.08	5.00765	No	No	19	4	3
156	G.H4.02	G.H4.05	3.26171	No	No	19	5	4
157	G.H4.03	G.H4.04	3.55168	Yes	No	0	4	4
158	G.H4.07	G.S6.05	3.11583	No	No	0	5	4
159	G.H4.10	G.H4.14	11.5358	No	No	18	6	5
160	G.H4.12	G.H4.16	5.05126	No	No	6	5	3
161	G.H4.12	G.S6.03	13.9883	No	No	6	5	5
162	G.H4.12	G.S6.05	4.53302	No	No	0	5	4
163	G.H4.16	G.S6.01	3.18363	No	No	0	3	5
164	G.H4.16	G.S6.03	3.88763	No	No	6	3	5
165	G.h4s6.02	G.h4s6.08	5.11862	Yes	No	0	8	3
166	G.S6.01	G.h4s6.02	5.51197	No	Yes	0	5	8
167	G.h4s6.04	G.h4s6.10	2.81816	No	No	0	4	3
168	G.h4s6.09	G.h4s6.10	4.12695	No	No	0	3	3
169	G.S6.02	G.h4s6.12	12.24	Yes	Yes	0	7	4
170	G.H5.10	G.S6.02	5.44347	No	Yes	0	6	7
171	G.H5.13	G.S6.02	6.03686	Yes	Yes	0	8	7
172	G.H5.03	G.S6.04	3.1767	Yes	No	12	8	9
173	G.H5.06	G.S6.04	20.3783	No	No	0	3	9
174	G.H5.03	G.s6h5.01	7.54563	Yes	No	12	8	9
175	G.H5.02	G.s6h5.04	3.17233	No	No	0	4	8
176	G.H5.08	G.H5.12	5.51392	Yes	No	0	8	6
177	5x68	G.H5.13	3.4676	No	Yes	0	7	8
178	G.H5.16	I2x50	4.17505	No	No	0	6	8
179	5x68	G.H5.16	3.3048	No	No	0	7	6
180	G.H5.17	G.H5.26	3.68612	No	Yes	0	5	5
181	G.H5.20	G.H5.25	2.8984	Yes	Yes	0	9	7
182	G.H5.20	G.H5.26	5.73568	Yes	Yes	0	9	5
183	3x54	G.H5.20	3.51473	No	Yes	0	9	9
184	5x65	G.H5.20	2.71592	No	Yes	0	8	9
185	G.H5.21	G.H5.26	4.31536	No	Yes	0	5	5
186	G.H5.23	G.H5.25	2.71737	No	Yes	2	4	7
187	3x50	G.H5.23	5.0621	Yes	No	2	9	4
188	6x29	G.H5.26	6.98162	No	Yes	0	7	5
189	b.b21x1	g.l1x4	9.33408	Yes	Yes	0	7	8
190	g.h2x3	g.l1x5	4.27834	No	No	0	5	4
191	b.b21x2	g.h2x1	3.49042	No	No	0	6	8
192	b.lh12x2	g.h2x2	5.08354	No	No	0	8	9
193	b.l20x2	g.h2x7	5.49639	Yes	No	0	9	5
194	b.l18x1	g.h2x8	6.12053	Yes	No	0	6	7
195	g.h2x11	g.h2x15	12.8432	Yes	No	0	6	6
196	b.l18x1	g.h2x11	4.14033	Yes	Yes	10	6	6
197	b.l18x2	g.h2x11	5.23281	Yes	Yes	10	7	6
198	b.l18x3	g.h2x11	10.7546	Yes	Yes	10	5	6
199	b.l22x5	g.h2x12	2.80038	Yes	No	8	9	7
200	b.l24x2	g.h2x12	5.31237	Yes	No	8	6	7
201	g.ctx2	g.h2x15	3.79143	No	No	0	3	6
202	g.ctx1	g.ctx2	2.7067	No	No	0	1	3
203	g.ctx3	g.ctx4	3.77686	Yes	No	0	9	7
204	g.ctx3	g.ctx6	7.42072	Yes	Yes	8	9	6
205	b.l22x1	g.ctx3	7.7122	No	Yes	8	9	9
206	b.l22x3	g.ctx3	8.79931	No	Yes	0	9	9
207	b.lhb1x11	g.ctx5	3.2426	No	Yes	0	4	9
208	b.l22x1	g.ctx5	2.73675	No	Yes	8	9	9
209	b.b27x1	g.ctx5	2.72735	No	Yes	0	6	9
210	b.lhb1x6	g.ctx6	2.6884	Yes	Yes	8	3	6
211	b.l22x5	g.ctx6	4.83219	Yes	Yes	8	9	6
212	g.ctx10	g.ctx9	3.5015	No	No	3	5	6
213	g.ctx13	g.ctx9	3.92238	No	No	3	5	6
214	g.ctx14	g.ctx9	2.9144	Yes	No	3	9	6
215	g.ctx10	g.ctx13	5.86142	No	No	3	5	5
216	g.ctx14	g.ctx15	4.5079	Yes	Yes	3	9	9
217	g.ctx14	g.ctx16	2.68444	Yes	Yes	3	9	8
218	b.b28x7	g.ctx14	8.46564	No	Yes	3	9	9
219	g.ctx15	g.ctx16	3.62663	Yes	Yes	3	9	8
220	b.l4x2	g.ctx15	10.126	Yes	Yes	3	4	9
221	b.l27x5	g.ctx15	5.42307	No	Yes	0	5	9
222	b.b1x4	g.ctx16	5.58818	No	Yes	3	7	8
223	b.l4x1	g.ctx16	4.148	No	Yes	0	5	8
224	b.l27x6	g.ctx16	4.16413	No	Yes	0	7	8
225	b.b28x5	g.ctx16	3.86769	No	Yes	3	5	8
226	b.b28x7	g.ctx16	3.91713	No	Yes	3	9	8
227	1x39	2x61	3.6951	Yes	No	0	7	7
228	1x39	7x39	3.88437	Yes	Yes	2	7	8
229	1x42	7x47	2.7302	No	No	0	7	7
230	1x43	2x57	4.58411	No	Yes	0	7	8
231	1x46	1x50	2.97864	No	Yes	0	8	9
232	1x46	2x54	2.93713	No	No	0	8	8
233	1x46	7x47	3.13763	No	No	0	8	7
234	1x50	2x50	7.86493	Yes	Yes	0	9	9
235	1x50	2x51	4.19258	Yes	Yes	0	9	8
236	1x50	7x50	7.12235	Yes	No	0	9	9
237	1x52	8x54	3.31899	No	No	0	8	8
238	1x53	7x54	2.68629	No	Yes	0	9	8
239	1x57	2x44	4.42476	No	No	0	8	6
240	1x60	I1x50	3.55941	Yes	No	0	7	8
241	1x60	8x53	3.14866	Yes	No	0	7	8
242	2x40	I1x50	4.44647	Yes	No	0	9	8
243	2x37	2x40	4.83395	No	Yes	0	8	9
244	2x38	I2x57	3.47719	No	No	0	7	8
245	2x39	3x49	4.33026	No	Yes	0	8	9
246	2x41	4x42	3.42736	No	No	0	6	7
247	2x42	3x46	2.71619	Yes	Yes	0	8	9
248	2x42	3x49	4.33312	Yes	Yes	0	8	9
249	2x42	4x42	2.7417	Yes	No	0	8	7
250	2x42	4x46	2.85253	Yes	No	0	8	8
251	2x45	3x42	6.31747	No	No	0	9	8
252	2x45	4x46	7.39034	No	No	0	9	8
253	2x46	2x50	3.95083	Yes	Yes	2	9	9
254	2x46	3x42	4.16212	Yes	No	0	9	8
255	2x46	3x43	3.42753	Yes	Yes	2	9	8
256	2x46	7x49	5.36134	Yes	Yes	2	9	9
257	2x49	4x50	2.82583	No	No	0	9	9
258	2x50	3x39	4.23729	Yes	No	0	9	9
259	2x50	7x46	6.69127	Yes	No	0	9	9
260	2x50	7x49	6.30138	Yes	Yes	2	9	9
261	2x53	2x57	3.08002	No	Yes	0	8	8
262	2x53	3x35	4.92346	No	No	0	8	7
263	2x56	3x31	2.87238	No	No	0	8	5
264	2x56	3x32	4.03587	No	No	0	8	8
265	2x57	7x42	6.43859	Yes	Yes	2	8	8
266	2x59	3x28	4.43912	No	No	0	6	6
267	2x62	2x66	2.81011	No	No	0	6	5
268	2x63	E1x50	5.15112	No	Yes	0	6	9
269	2x64	7x35	2.77524	Yes	No	2	7	6
270	2x66	E1x51	3.458	No	No	0	5	5
271	E1x49	E2	3.85477	No	Yes	0	5	5
272	E1x50	E1x52	8.73901	Yes	Yes	0	9	7
273	3x25	E1x50	5.08562	No	Yes	2	9	9
274	E1x50	E2x50	6.38206	Yes	No	2	9	9
275	E1x51	E1x52	3.10109	No	Yes	0	5	7
276	3x24	E1x52	5.30026	No	Yes	0	6	7
277	3x22	3x26	4.40096	No	No	2	4	7
278	3x25	E2x50	6.45659	No	No	2	9	9
279	3x30	4x57	3.04714	No	No	0	7	8
280	3x30	4x61	3.68785	No	No	0	7	6
281	3x32	7x42	2.7936	No	Yes	2	8	8
282	3x32	Lig	6.89137	No	Yes	2	8	0
283	3x33	4x57	2.99009	No	No	0	8	8
284	3x33	Lig	5.76865	No	Yes	2	8	0
285	3x34	4x54	5.04394	No	No	0	6	5
286	3x34	4x57	4.33408	No	No	0	6	8
287	3x36	6x48	3.93863	No	Yes	2	7	8
288	3x36	Lig	5.76671	No	Yes	2	7	0
289	3x37	3x41	3.39407	Yes	No	0	8	7
290	3x37	4x53	2.79817	Yes	No	0	8	8
291	3x37	4x56	3.84746	Yes	No	0	8	8
292	3x37	5x461	4.19532	Yes	No	0	8	8
293	3x38	4x50	6.98274	No	No	0	8	9
294	3x40	5x50	3.25876	No	No	0	8	9
295	3x40	6x48	7.45958	No	Yes	2	8	8
296	3x41	4x49	3.40246	No	No	0	7	8
297	3x42	4x49	3.63774	No	No	0	8	8
298	3x43	6x44	3.3721	Yes	Yes	2	8	9
299	3x43	7x49	3.83296	Yes	Yes	2	8	9
300	3x43	7x53	5.49294	Yes	Yes	2	8	9
301	3x44	5x50	3.55909	No	No	0	7	9
302	3x44	5x53	3.63388	No	No	0	7	7
303	3x46	3x50	4.89409	Yes	Yes	2	9	9
304	3x46	7x53	4.30698	Yes	Yes	2	9	9
305	3x47	5x54	3.69516	No	No	0	9	9
306	3x47	5x57	2.76009	No	No	0	9	7
307	3x47	5x58	4.79979	No	Yes	0	9	9
308	3x49	I2x57	5.03521	Yes	No	20	9	8
309	3x50	5x58	5.01114	Yes	Yes	0	9	9
310	3x50	7x53	5.66399	Yes	Yes	2	9	9
311	3x51	3x55	9.01462	No	No	0	9	8
312	3x51	5x57	6.39861	No	No	0	9	7
313	3x51	5x60	6.22532	No	No	0	9	7
314	3x53	I2x53	7.21045	No	Yes	0	8	8
315	3x54	5x61	4.66281	No	No	0	9	9
316	3x55	3x56	2.96468	No	No	0	8	7
317	3x56	I2x52	3.19948	No	No	0	7	6
318	I2x52	I2x56	3.29177	No	No	0	6	5
319	I2x53	I2x57	3.89756	Yes	No	20	8	8
320	4x59	4x60	3.52022	No	No	0	8	7
321	4x60	5x39	5.39736	No	No	0	7	8
322	E2	E2x51	6.45882	Yes	No	2	5	5
323	E2x52	Lig	8.64019	No	Yes	2	6	0
324	5x36	E2	5.62848	No	Yes	2	6	5
325	5x39	E2	4.43608	No	Yes	2	8	5
326	5x36	5x38	2.83867	No	No	0	6	5
327	5x39	5x43	3.34632	No	No	2	8	8
328	5x40	6x59	2.91158	No	Yes	0	7	7
329	5x43	Lig	4.01341	No	Yes	2	8	0
330	5x44	6x52	5.40564	No	No	0	7	7
331	5x44	6x56	2.65848	No	No	0	7	7
332	5x47	5x51	3.65151	Yes	No	0	8	7
333	5x47	6x48	2.70102	Yes	Yes	2	8	8
334	5x47	6x49	3.60547	Yes	Yes	0	8	7
335	5x47	6x52	11.3894	Yes	No	2	8	7
336	5x49	5x50	3.7592	No	No	0	6	9
337	5x51	6x44	4.21643	No	Yes	0	7	9
338	5x54	6x44	2.73113	No	Yes	0	9	9
339	5x55	6x41	2.8978	No	No	0	6	8
340	5x56	5x60	4.54452	No	No	0	5	7
341	5x58	6x37	5.908	Yes	No	0	9	8
342	5x58	6x40	3.76461	Yes	No	0	9	8
343	5x58	6x41	5.05239	Yes	No	0	9	8
344	5x62	5x66	3.20874	No	No	0	6	7
345	5x62	6x34	4.6702	No	No	0	6	8
346	6x32	6x36	2.68443	No	No	0	8	8
347	6x40	7x53	5.00569	No	Yes	0	8	9
348	6x44	6x48	6.80449	Yes	Yes	2	9	8
349	6x45	6x49	2.81082	No	Yes	0	7	7
350	6x47	7x45	6.07591	No	No	0	8	9
351	6x48	6x52	3.08543	Yes	No	2	8	7
352	6x48	7x41	4.98117	Yes	No	0	8	8
353	6x48	7x45	8.88264	Yes	No	0	8	9
354	6x49	6x50	2.68036	Yes	No	0	7	9
355	6x51	7x37	2.8621	Yes	No	0	8	6
356	6x51	7x38	4.73115	Yes	No	2	8	7
357	6x51	Lig	5.88919	Yes	Yes	2	8	0
358	6x54	7x37	3.17063	No	No	0	6	6
359	6x55	Lig	3.87678	No	Yes	2	8	0
360	6x58	E3	3.06914	No	Yes	0	4	4
361	6x61	E3	6.22822	No	Yes	0	5	4
362	E3	E3	7.2189	Yes	Yes	2	4	4
363	7x38	7x42	4.69333	No	Yes	2	7	8
364	7x42	Lig	4.48438	Yes	Yes	2	8	0
365	7x45	7x49	7.50435	No	Yes	0	9	9
366	7x52	7x53	2.84057	No	Yes	0	8	9
367	7x54	8x50	3.84527	Yes	Yes	0	8	8
368	8x47	8x50	3.4917	No	Yes	0	9	8
369	8x48	8x51	4.43685	No	No	0	6	9
370	b.b21x2	b.lh12x1	2.88124	No	No	0	6	3
371	b.h2x3	b.lh12x4	7.31042	No	No	0	1	3
372	b.h2x1	b.h2x5	3.17501	Yes	Yes	0	5	5
373	b.b21x4	b.h2x1	2.85902	No	Yes	0	5	5
374	b.b21x5	b.h2x1	6.32402	Yes	Yes	0	4	5
375	b.h2x5	b.l24x2	4.69087	Yes	Yes	0	5	6
376	b.l22x5	b.lhb1x3	4.114	Yes	Yes	0	9	2
377	b.lhb1x4	b.lhb1x5	3.61941	No	No	0	1	1
378	b.l24x3	b.lhb1x5	2.97007	Yes	No	0	5	1
379	b.l22x5	b.lhb1x6	5.3206	Yes	Yes	8	9	3
380	b.b24x7	b.lhb1x6	6.24036	No	Yes	8	9	3
381	b.lhb1x11	b.lhb1x9	2.85349	No	No	0	4	3
382	b.b23x1	b.lhb1x9	2.96897	No	No	0	5	3
383	b.b25x7	b.lhb1x11	5.52798	No	No	0	7	4
384	b.b1x2	b.b28x4	7.42071	No	Yes	11	3	6
385	b.b1x2	b.b28x6	8.81903	No	Yes	11	3	9
386	b.b1x3	b.b28x7	8.22044	No	No	0	7	9
387	b.b1x4	b.b5x1	3.73531	No	No	0	7	5
388	b.b1x4	b.b28x5	3.98097	No	No	3	7	5
389	b.b1x5	b.l1x1	7.74251	No	No	0	3	7
390	b.b1x5	b.b28x4	6.02254	No	Yes	0	3	6
391	b.b1x6	b.b4x6	16.4595	Yes	Yes	3	9	9
392	b.b1x6	b.b5x1	2.90471	Yes	No	0	9	5
393	b.b1x6	b.b28x3	6.60297	Yes	Yes	3	9	7
394	b.b28x2	b.l1x1	6.52414	Yes	No	0	4	7
395	b.l1x3	b.l1x7	9.09186	Yes	No	0	9	9
396	b.b3x4	b.l1x3	7.50566	No	Yes	3	9	9
397	b.b3x6	b.l1x3	12.2042	No	Yes	3	9	9
398	b.l1x3	b.l3x2	3.66156	Yes	Yes	3	9	9
399	b.b4x4	b.l1x3	12.0682	No	Yes	3	8	9
400	b.b4x6	b.l1x3	3.42897	Yes	Yes	3	9	9
401	b.l1x5	b.l3x2	3.34806	No	Yes	0	7	9
402	b.b2x1	b.l1x6	6.15395	Yes	No	1	8	9
403	b.l1x6	b.l28x1	22.4349	No	Yes	1	9	9
404	b.b28x3	b.l1x7	3.00255	Yes	No	0	7	9
405	b.b2x1	b.l3x1	12.8231	Yes	No	1	8	9
406	b.b2x1	b.l28x1	7.72347	Yes	Yes	1	8	9
407	b.b2x3	b.b2x5	4.25265	No	Yes	3	6	7
408	b.b2x3	b.b3x2	3.45902	No	No	3	6	5
409	b.b26x2	b.b2x3	5.18785	No	No	0	7	6
410	b.b2x4	b.b6x5	2.98502	No	Yes	0	6	6
411	b.b10x4	b.b2x4	11.5709	No	No	0	6	6
412	b.b2x5	b.b3x2	10.395	Yes	No	3	7	5
413	b.b2x5	b.l4x1	5.16159	Yes	No	0	7	5
414	b.b2x5	b.l27x1	11.3991	Yes	No	3	7	7
415	b.b27x2	b.b2x5	4.14549	No	Yes	0	5	7
416	b.b6x5	b.l2x1	4.48009	Yes	No	0	6	5
417	b.l27x2	b.l2x2	2.96013	No	No	0	1	1
418	b.l2x3	b.l2x5	2.89799	No	No	0	8	5
419	b.l27x1	b.l2x4	6.3694	No	No	3	7	5
420	b.l27x3	b.l2x4	9.13255	No	No	3	7	5
421	b.b4x7	b.l2x5	14.103	No	No	0	8	5
422	b.l2x5	b.l4x2	22.4287	No	Yes	0	5	4
423	b.b3x1	b.b6x5	3.92033	No	Yes	0	5	6
424	b.b3x2	b.b4x6	5.43015	No	Yes	3	5	9
425	b.b3x3	b.b4x3	3.44507	No	Yes	0	8	7
426	b.b3x3	b.b4x5	3.19545	No	Yes	0	8	7
427	b.b3x3	b.b6x5	5.06635	No	Yes	0	8	6
428	b.b3x4	b.b4x6	6.49212	No	Yes	3	9	9
429	b.b28x3	b.b3x4	4.14895	Yes	No	3	7	9
430	b.b3x5	b.l5x6	2.92435	No	No	0	9	9
431	b.b3x5	b.b6x3	3.03875	No	No	0	9	8
432	b.b3x6	b.l3x2	7.75933	No	Yes	3	9	9
433	b.l3x1	b.l5x5	5.91918	No	Yes	1	9	9
434	b.b4x2	b.l3x2	6.32843	Yes	Yes	0	8	9
435	b.b4x1	b.l5x1	3.21705	No	Yes	0	8	8
436	b.b4x2	b.b5x8	2.77447	Yes	No	0	8	5
437	b.b4x3	b.b5x7	5.53936	Yes	Yes	0	7	7
438	b.b4x3	b.b7x4	4.11775	Yes	Yes	5	7	8
439	b.b4x4	b.b4x6	14.8791	No	Yes	3	8	9
440	b.b4x4	b.b5x3	4.6518	No	Yes	3	8	9
441	b.b4x5	b.b5x4	3.08504	Yes	No	5	7	5
442	b.b4x5	b.b5x5	6.57373	Yes	Yes	5	7	5
443	b.b4x5	b.l8x1	3.75903	Yes	No	5	7	5
444	b.b4x6	b.b5x3	10.5083	Yes	Yes	3	9	9
445	b.b28x3	b.b4x6	2.77748	Yes	Yes	3	7	9
446	b.b4x7	b.l4x3	7.9823	No	No	0	8	6
447	b.b5x2	b.l4x3	10.0856	Yes	No	0	7	6
448	b.b5x4	b.b5x5	6.10903	No	Yes	5	5	5
449	b.b5x5	b.l8x8	3.64628	Yes	No	0	5	4
450	b.b5x7	b.b5x8	3.36052	Yes	No	0	7	5
451	b.b5x7	b.b8x4	5.69706	Yes	Yes	0	7	6
452	b.b5x7	b.l8x8	6.39165	Yes	No	0	7	4
453	b.l5x1	b.l5x6	3.98225	Yes	No	5	8	9
454	b.b7x4	b.l5x1	3.53069	Yes	Yes	5	8	8
455	b.b8x4	b.l5x1	4.97472	Yes	Yes	5	6	8
456	b.b9x3	b.l5x2	7.10029	No	Yes	0	6	6
457	b.l5x3	b.l7x3	9.3539	No	No	0	8	9
458	b.l5x5	b.l7x2	5.40752	Yes	Yes	1	9	9
459	b.b7x4	b.l5x6	3.00607	Yes	No	5	8	9
460	b.b6x1	b.l7x1	2.89374	No	No	0	9	9
461	b.b10x3	b.b6x2	4.3301	No	No	0	8	8
462	b.b6x5	b.l6x4	4.12025	Yes	No	0	6	5
463	b.b6x5	b.l8x1	2.75603	Yes	No	5	6	5
464	b.b10x5	b.l6x1	6.1403	Yes	No	0	9	6
465	b.b10x5	b.l6x2	2.99321	Yes	No	0	9	6
466	b.l6x3	b.l6x5	6.99686	No	Yes	13	6	4
467	b.l10x3	b.l6x3	8.80824	No	No	13	6	6
468	b.b7x1	b.l6x5	3.84254	Yes	Yes	13	4	4
469	b.l6x5	b.l8x2	8.15624	Yes	No	0	4	4
470	b.l10x3	b.l6x5	4.26754	No	Yes	13	6	4
471	b.b7x1	b.b8x3	3.28167	Yes	Yes	0	4	6
472	b.b7x1	b.b8x5	10.1207	Yes	No	0	4	4
473	b.b7x1	b.l10x3	7.1685	Yes	No	13	4	6
474	b.b7x2	b.b8x4	2.86649	No	Yes	5	8	6
475	b.b7x2	b.l8x1	4.83464	No	No	5	8	5
476	b.b10x5	b.b7x3	3.3748	Yes	No	0	9	9
477	b.b7x4	b.b8x4	3.1942	Yes	Yes	5	8	6
478	b.l7x2	b.l9x6	2.74399	Yes	Yes	1	9	8
479	b.l7x3	b.l7x5	5.13537	No	Yes	0	9	6
480	b.l7x4	b.l9x5	3.96749	Yes	No	0	9	8
481	b.b9x3	b.l7x5	4.0944	No	Yes	0	6	6
482	b.b10x3	b.b8x1	3.27406	No	No	1	8	8
483	b.b8x2	b.b8x4	6.10742	No	Yes	0	8	6
484	b.b8x2	b.b9x3	4.3694	No	No	0	8	6
485	b.b10x5	b.b8x3	3.01038	Yes	Yes	0	9	6
486	b.b8x3	b.l12x1	4.63145	Yes	No	0	6	6
487	b.b8x4	b.l8x10	5.20745	Yes	No	0	6	4
488	b.b8x5	b.l8x3	4.32179	No	No	0	4	3
489	b.l8x3	b.l8x9	3.5038	No	No	0	3	3
490	b.l8x5	b.l8x7	2.98255	Yes	No	0	3	3
491	b.b12x6	b.b9x4	15.3118	Yes	No	0	8	9
492	b.l9x3	b.l9x7	4.00267	Yes	No	1	9	7
493	b.b11x4	b.l9x3	5.77543	Yes	Yes	1	9	9
494	b.b11x6	b.l9x3	15.2409	No	Yes	1	9	9
495	b.b12x4	b.l9x3	2.99458	No	Yes	1	4	9
496	b.b12x6	b.l9x3	6.05697	Yes	Yes	1	8	9
497	b.l11x2	b.l9x4	7.08119	Yes	No	0	9	5
498	b.l11x1	b.l9x6	5.52424	No	Yes	1	9	8
499	b.l13x6	b.l9x6	6.99765	Yes	Yes	1	9	8
500	b.b14x1	b.l9x6	3.88895	No	Yes	1	8	8
501	b.b11x4	b.l9x7	4.40147	Yes	No	1	9	7
502	b.b10x1	b.b11x5	3.19628	No	No	0	9	6
503	b.b10x2	b.b10x4	4.06152	No	No	0	6	6
504	b.b10x2	b.b14x3	4.15616	No	Yes	0	6	5
505	b.b10x3	b.b11x4	2.80316	No	Yes	1	8	9
506	b.b10x4	b.b14x5	2.86602	No	No	0	6	5
507	b.b10x5	b.b11x2	7.08513	Yes	No	0	9	7
508	b.b11x1	b.l10x1	4.82779	No	No	0	5	3
509	b.b14x5	b.l10x1	5.02182	No	No	0	5	3
510	b.l10x1	b.l14x4	2.79995	No	No	0	3	1
511	b.l10x4	b.l12x2	6.50004	No	No	21	3	6
512	b.b11x1	b.b12x5	5.1667	No	No	0	5	6
513	b.b11x2	b.b12x6	2.78997	No	Yes	0	7	8
514	b.b11x2	b.l12x1	3.58863	No	No	0	7	6
515	b.b11x3	b.b14x3	3.55694	No	Yes	4	5	5
516	b.b11x3	b.b15x1	3.51719	No	Yes	4	5	9
517	b.b11x4	b.b12x6	9.56391	Yes	Yes	1	9	8
518	b.b11x5	b.l13x7	5.47786	No	Yes	0	6	9
519	b.b11x5	b.b14x3	4.59257	No	Yes	0	6	5
520	b.b11x6	b.l11x1	2.94992	No	No	1	9	9
521	b.b11x6	b.l11x2	8.42061	No	Yes	1	9	9
522	b.l11x1	b.l13x6	3.94765	No	Yes	1	9	9
523	b.b12x2	b.l11x2	8.42458	No	Yes	0	7	9
524	b.b12x2	b.l13x1	3.5412	No	No	0	7	2
525	b.b12x3	b.b13x7	3.70103	No	Yes	4	8	7
526	b.b12x3	b.l13x7	3.70198	No	Yes	4	8	9
527	b.b12x3	b.b15x3	3.13281	No	Yes	4	8	9
528	b.b12x4	b.b12x6	4.66256	No	Yes	1	4	8
529	b.b12x4	b.b13x3	5.12105	No	No	1	4	4
530	b.b12x5	b.b13x5	4.69864	No	No	0	6	4
531	b.b12x6	b.b13x3	13.6149	Yes	No	1	8	4
532	b.b12x7	b.l12x2	2.98892	Yes	No	21	9	6
533	b.b12x7	b.l12x3	7.35067	Yes	No	0	9	5
534	b.b12x7	b.b13x4	2.6645	Yes	No	0	9	4
535	b.b13x3	b.b13x6	5.77391	No	No	0	4	4
536	b.b13x4	b.b13x5	2.99718	No	No	0	4	4
537	b.b13x5	b.b13x7	5.64497	No	Yes	0	4	7
538	b.b13x7	b.b15x1	10.2037	Yes	Yes	4	7	9
539	b.b13x7	b.b16x6	13.6625	Yes	Yes	4	7	8
540	b.b13x7	b.b17x1	3.6284	Yes	No	0	7	4
541	b.l13x3	b.l13x7	6.09543	Yes	Yes	4	9	9
542	b.b15x5	b.l13x3	8.16301	No	Yes	4	8	9
543	b.l13x3	b.l15x2	5.15142	Yes	Yes	4	9	9
544	b.b16x4	b.l13x3	14.7761	Yes	Yes	4	6	9
545	b.b16x6	b.l13x3	3.87379	Yes	Yes	4	8	9
546	b.l13x4	b.l15x2	7.09195	No	Yes	0	3	9
547	b.l13x6	b.l15x1	4.17128	Yes	Yes	1	9	7
548	b.b15x3	b.l13x7	3.09785	Yes	Yes	4	9	9
549	b.b14x1	b.l15x1	2.9456	No	Yes	1	8	7
550	b.b14x2	b.b18x3	5.06708	No	Yes	0	7	8
551	b.b14x3	b.b15x1	3.96315	Yes	Yes	4	5	9
552	b.b14x4	b.b18x5	6.07845	No	Yes	0	8	5
553	b.l14x1	b.l14x3	2.88847	No	No	0	4	5
554	b.b18x5	b.l14x1	4.2169	Yes	No	0	5	4
555	b.l14x2	b.l18x4	3.24346	No	No	0	4	7
556	b.l14x3	b.l14x5	7.69458	No	No	0	5	5
557	b.l14x5	b.l16x2	5.58849	No	No	0	5	9
558	b.b16x5	b.l14x6	4.3408	Yes	No	0	5	3
559	b.b16x7	b.l14x6	4.10196	No	No	0	9	3
560	b.b15x1	b.b16x6	12.0165	Yes	Yes	4	9	8
561	b.b15x2	b.b16x5	3.2297	Yes	Yes	0	6	5
562	b.b15x2	b.b18x3	5.35345	Yes	Yes	1	6	8
563	b.b15x2	b.b18x5	7.41709	Yes	Yes	0	6	5
564	b.b15x2	b.b19x2	7.62121	Yes	Yes	1	6	6
565	b.b15x3	b.b16x6	6.56917	Yes	Yes	4	9	8
566	b.b15x4	b.l17x7	3.3102	No	No	0	6	7
567	b.l15x1	b.l17x6	9.3233	Yes	Yes	1	7	9
568	b.b16x2	b.l15x2	7.73829	No	Yes	0	5	9
569	b.b16x4	b.b16x6	7.62242	Yes	Yes	4	6	8
570	b.b16x4	b.b17x3	6.87023	Yes	No	4	6	5
571	b.b16x4	b.b17x6	10.8495	Yes	No	0	6	7
572	b.b16x5	b.l20x1	5.99313	Yes	No	0	5	6
573	b.b16x6	b.b17x3	5.9109	Yes	No	4	8	5
574	b.b16x7	b.l16x3	8.94736	No	Yes	22	9	3
575	b.b16x7	b.b17x4	8.64807	No	No	22	9	5
576	b.b17x2	b.l16x3	4.26852	No	Yes	0	3	3
577	b.b17x4	b.l16x3	2.66432	No	Yes	22	5	3
578	b.b17x5	b.b17x7	7.52541	Yes	Yes	1	7	8
579	b.b17x5	b.b21x1	12.1676	Yes	Yes	1	7	7
580	b.b17x7	b.b19x2	10.5143	Yes	Yes	1	8	6
581	b.b17x7	b.b20x6	8.78632	Yes	Yes	1	8	6
582	b.b17x7	b.b21x1	4.34074	Yes	Yes	1	8	7
583	b.l17x3	b.l17x7	7.64119	Yes	No	1	9	7
584	b.b19x4	b.l17x3	8.58922	Yes	Yes	1	8	9
585	b.b19x6	b.l17x3	13.56	No	Yes	1	9	9
586	b.b20x4	b.l17x3	16.8634	Yes	Yes	1	8	9
587	b.l17x4	b.l19x2	7.87839	No	Yes	0	3	9
588	b.l17x5	b.l17x6	2.98783	No	Yes	1	6	9
589	b.l17x5	b.l19x1	3.52338	No	No	1	6	9
590	b.l17x5	b.l19x2	3.7798	No	Yes	1	6	9
591	b.l17x6	b.l19x1	5.59111	Yes	No	1	9	9
592	b.b18x1	b.l19x1	10.2347	No	No	0	9	9
593	b.b18x3	b.b19x2	4.79976	Yes	Yes	1	8	6
594	b.b18x3	b.b19x4	4.51263	Yes	Yes	1	8	8
595	b.l18x1	b.l18x2	10.3015	Yes	Yes	10	6	7
596	b.l18x1	b.l18x3	5.90111	Yes	Yes	10	6	5
597	b.b22x5	b.l18x1	8.59419	Yes	Yes	10	7	6
598	b.l18x1	b.l22x4	4.20882	Yes	No	10	6	9
599	b.b22x5	b.l18x2	4.11077	Yes	Yes	10	7	7
600	b.l18x2	b.l22x4	3.47746	Yes	No	10	7	9
601	b.l18x3	b.l18x5	8.30596	Yes	No	0	5	2
602	b.l18x5	b.l20x2	10.4366	No	Yes	0	2	9
603	b.b19x2	b.b20x6	10.404	Yes	Yes	1	6	6
604	b.b19x2	b.l20x1	2.8577	Yes	No	0	6	6
605	b.b19x3	b.b22x5	3.08272	No	Yes	0	4	7
606	b.b19x4	b.b20x6	7.17161	Yes	Yes	1	8	6
607	b.b19x5	b.l21x9	4.30497	No	No	0	5	6
608	b.b19x6	b.l19x2	6.9244	No	Yes	1	9	9
609	b.b20x2	b.l19x2	7.97056	No	Yes	0	6	9
610	b.b20x2	b.b20x4	7.0621	No	Yes	0	6	8
611	b.b20x2	b.l21x1	4.16493	No	No	0	6	2
612	b.b20x3	b.b21x7	3.72916	No	Yes	0	8	5
613	b.b20x3	b.l21x9	4.2487	No	No	0	8	6
614	b.b20x4	b.b20x6	4.32738	Yes	Yes	1	8	6
615	b.b20x4	b.b21x3	15.0985	Yes	No	1	8	6
616	b.b20x4	b.b21x6	7.29809	Yes	No	1	8	1
617	b.b20x5	b.b21x4	3.80873	No	No	0	7	5
618	b.b20x5	b.b21x7	5.24524	No	Yes	0	7	5
619	b.b20x6	b.b21x3	5.11016	Yes	No	1	6	6
620	b.b20x7	b.l20x3	4.04575	Yes	No	0	9	7
621	b.b20x7	b.b21x4	6.81086	Yes	No	0	9	5
622	b.b21x3	b.b21x6	4.07743	No	No	1	6	1
623	b.b21x5	b.b21x7	8.48512	Yes	Yes	0	4	5
624	b.b21x5	b.b25x1	2.88789	Yes	No	0	4	2
625	b.b21x7	b.b23x2	4.53476	Yes	No	0	5	6
626	b.b21x7	b.b24x6	7.55943	Yes	Yes	0	5	8
627	b.l21x2	b.l21x4	6.5703	Yes	No	0	4	4
628	b.l21x2	b.l21x5	3.23614	Yes	No	0	4	4
629	b.b23x6	b.l21x5	6.18923	Yes	No	0	7	4
630	b.l21x7	b.l23x1	4.44105	No	Yes	0	5	6
631	b.l21x7	b.l23x2	7.13131	No	No	0	5	8
632	b.l21x8	b.l23x1	3.11614	No	Yes	0	4	6
633	b.b23x6	b.l21x9	10.1356	Yes	No	0	7	6
634	b.b22x1	b.b22x2	3.34574	No	No	0	8	8
635	b.b22x1	b.l23x1	3.49552	No	Yes	0	8	6
636	b.b22x2	b.b26x3	4.39674	No	No	0	8	6
637	b.b22x4	b.b26x3	3.24996	No	No	0	5	6
638	b.b22x4	b.b26x5	3.28024	No	No	0	5	7
639	b.b22x5	b.b23x2	8.23687	Yes	No	0	7	6
640	b.b23x1	b.l22x1	3.15856	No	No	0	5	9
641	b.b24x7	b.l22x5	13.0707	No	Yes	8	9	9
642	b.l22x5	b.l24x2	8.61645	Yes	Yes	8	9	6
643	b.b23x1	b.b24x5	5.1187	No	No	0	5	5
644	b.b23x3	b.b24x5	4.5187	No	No	0	7	5
645	b.b23x3	b.b27x1	4.27134	No	No	0	7	6
646	b.b23x4	b.b23x6	4.46656	No	Yes	0	6	7
647	b.b23x5	b.l25x7	2.83239	No	No	0	7	7
648	b.b23x6	b.l23x2	3.30438	Yes	No	0	7	8
649	b.b23x6	b.b24x6	6.89932	Yes	Yes	14	7	8
650	b.l23x1	b.l25x6	18.7549	Yes	No	0	6	8
651	b.b24x2	b.l23x2	5.75053	No	No	0	5	8
652	b.b24x3	b.b25x7	5.02912	No	No	0	5	7
653	b.b24x4	b.b24x6	4.92112	Yes	Yes	14	6	8
654	b.b24x4	b.b25x3	10.4739	Yes	No	14	6	5
655	b.b24x7	b.l24x3	7.411	No	Yes	0	9	5
656	b.b25x2	b.l24x3	3.63076	No	Yes	0	2	5
657	b.b25x7	b.b28x6	15.3234	No	Yes	0	7	9
658	b.l25x3	b.l25x7	3.88146	Yes	No	0	9	7
659	b.b27x3	b.l25x3	7.11339	No	Yes	0	8	9
660	b.b27x5	b.l25x3	13.7103	No	Yes	11	9	9
661	b.l25x3	b.l28x2	7.14157	Yes	Yes	11	9	9
662	b.b28x4	b.l25x3	8.11035	Yes	Yes	11	6	9
663	b.l25x4	b.l28x2	4.73984	No	Yes	0	5	9
664	b.l25x5	b.l28x1	7.5302	No	Yes	0	7	9
665	b.l25x6	b.l28x1	21.0398	No	Yes	1	8	9
666	b.b26x1	b.l28x1	5.38528	No	Yes	0	9	9
667	b.b26x3	b.b27x3	3.35922	No	No	0	6	8
668	b.b26x5	b.b27x1	3.84497	No	No	0	7	6
669	b.b27x3	b.b28x6	8.02569	No	Yes	0	8	9
670	b.b27x5	b.l28x2	7.5851	No	Yes	11	9	9
671	b.b28x2	b.l28x2	7.77458	Yes	Yes	0	4	9
672	b.b28x4	b.b28x6	7.32898	Yes	Yes	11	6	9
673	G.HN.37	b.b5x2	3.72586	No	Yes	0	3	7
674	G.S2.03	G.S2.05	3.92682	Yes	Yes	1	9	3
675	G.S2.03	G.S3.04	3.73484	Yes	Yes	1	9	6
676	G.S2.04	G.S3.05	2.73638	No	No	0	6	7
677	G.S2.05	G.S3.02	5.16283	Yes	No	0	3	4
678	G.s3h2.03	b.l7x2	3.7339	Yes	Yes	1	9	9
679	G.s3h2.03	b.l7x4	4.04027	Yes	Yes	0	9	9
680	G.H2.03	G.H2.06	2.99006	No	Yes	1	9	9
681	G.s4h3.04	G.s4h3.05	11.3761	Yes	Yes	9	8	9
682	G.HG.07	G.s4h3.04	6.90949	No	Yes	9	9	8
683	G.HG.08	G.s4h3.04	3.27025	No	Yes	9	6	8
684	G.HG.13	G.s4h3.04	3.77322	Yes	Yes	9	7	8
685	G.HG.13	G.s4h3.05	3.23001	Yes	Yes	9	7	9
686	G.HG.17	G.s4h3.05	3.25744	No	Yes	0	3	9
687	G.H3.10	G.h4s6.01	5.08161	No	No	0	5	4
688	G.H4.03	G.HG.05	11.1357	Yes	No	0	4	5
689	G.HG.15	G.hgh4.02	3.77434	No	Yes	0	7	7
690	G.HG.15	G.hgh4.05	7.563	No	Yes	0	7	7
691	G.hgh4.02	G.hgh4.04	2.99508	Yes	No	0	7	6
692	G.hgh4.03	G.hgh4.04	4.20024	No	No	0	5	6
693	G.H5.17	G.h4s6.12	3.76345	No	Yes	0	5	4
694	G.H5.05	G.H5.09	7.31052	No	No	0	5	4
695	G.H5.13	G.H5.17	3.18496	Yes	No	0	8	5
696	3x53	G.H5.19	4.51069	No	No	0	8	8
697	b.1x11	g.h1x11	4.79993	No	No	0	6	9
698	b.1x15	b.1x19	4.30639	No	No	0	4	2
699	b.1x19	b.b21x2	3.82292	No	No	0	2	6
700	b.lh12x2	g.l1x6	8.56418	No	No	0	8	4
701	b.b1x1	b.lhb1x10	3.65347	No	No	0	5	4
702	b.b1x1	b.b1x3	6.48441	No	No	0	5	7
703	b.b1x6	b.b28x5	3.53765	Yes	No	3	9	5
704	b.b3x1	b.l2x3	6.37813	No	No	0	5	8
705	b.b4x3	b.l5x1	4.0032	Yes	Yes	5	7	8
706	b.l4x2	g.ctx16	5.99767	Yes	Yes	3	4	8
707	b.b6x1	b.l9x6	4.6394	No	Yes	0	9	8
708	b.b6x5	b.b7x2	3.05258	Yes	No	5	6	8
709	b.b11x4	b.b8x1	2.68339	Yes	No	1	9	8
710	b.l8x5	b.l8x9	2.89942	Yes	No	0	3	3
711	b.l11x2	b.l9x3	7.02489	Yes	Yes	1	9	9
712	b.b11x1	b.l10x2	5.66648	No	No	0	5	5
713	b.b12x7	b.l10x4	7.08375	Yes	No	21	9	3
714	b.b13x2	b.l12x3	4.33056	No	No	0	4	5
715	b.b15x3	b.l13x3	5.54796	Yes	Yes	4	9	9
716	b.b16x5	b.b17x5	4.09805	Yes	Yes	0	5	7
717	b.b17x3	g.h1x10	4.4328	No	No	0	5	9
718	b.b17x6	g.h1x14	6.15338	No	No	0	7	9
719	b.b19x4	b.l17x7	4.20585	Yes	No	1	8	7
720	b.b20x7	g.h2x4	3.7829	Yes	No	0	9	7
721	b.l20x2	g.l1x5	6.29337	Yes	No	0	9	4
722	b.b25x3	b.l21x2	7.0919	No	Yes	0	5	4
723	b.b23x6	b.b24x4	10.4781	Yes	Yes	14	7	6
724	b.b24x2	b.b25x6	3.27421	No	No	0	5	3
725	b.b24x4	b.b25x6	3.93595	Yes	No	0	6	3
726	b.b24x6	b.b25x3	4.62381	Yes	No	14	8	5
727	b.l27x1	b.l27x3	6.3607	No	No	3	7	7
728	b.l27x3	b.l27x5	6.7945	No	No	0	7	5
729	b.l27x5	g.ctx4	5.77563	No	No	0	5	7
730	g.l1x2	g.l1x4	5.25391	No	Yes	0	2	8
731	1x35	1x39	4.9707	Yes	Yes	2	5	7
732	1x35	2x64	3.64724	Yes	Yes	2	5	7
733	1x43	2x58	3.71531	No	No	0	7	9
734	2x40	8x50	3.12956	Yes	Yes	0	9	8
735	2x52	3x35	4.67353	No	No	0	7	7
736	2x53	7x46	3.9873	No	No	0	8	9
737	3x40	6x44	3.14828	No	Yes	2	8	9
738	E2	E2	47.0989	Yes	Yes	2	5	5
739	6x50	7x40	2.80985	No	No	0	9	8
740	6x51	6x55	3.88914	Yes	No	2	8	8
741	G.HN.11	G.HN.33	3.40958	Yes	No	0	2	4
742	G.S3.01	I2x51	3.19087	Yes	No	0	4	6
743	G.H2.02	b.l13x6	3.15792	No	Yes	1	8	9
744	G.H2.05	G.H2.06	3.17324	No	Yes	1	8	9
745	G.H2.05	b.l17x6	3.25695	No	Yes	1	8	9
746	G.H3.03	G.s4h3.15	6.22445	No	No	0	4	9
747	G.H3.09	G.H3.13	3.68557	Yes	Yes	6	9	5
748	G.H3.09	G.H4.15	4.75448	Yes	Yes	6	9	8
749	G.h4s6.02	G.h4s6.11	5.38592	Yes	Yes	6	8	7
750	G.H5.13	I3	2.7058	Yes	No	0	8	0
751	g.h2x3	g.h2x7	3.83235	No	No	0	5	5
752	g.ctx3	g.ctx5	2.68932	Yes	Yes	8	9	9
753	1x55	1x59	3.95926	No	Yes	0	5	6
754	I1x48	I1x51	2.89405	No	No	0	7	8
755	2x42	3x45	4.62702	Yes	No	0	8	8
756	2x45	4x50	3.89403	No	No	0	9	9
757	3x38	4x53	3.16571	No	No	0	8	8
758	3x49	I2x53	3.4197	Yes	Yes	20	9	8
759	4x38	4x41	3.68747	No	No	0	8	7
760	4x64	E2	5.35384	No	Yes	0	0	5
761	6x36	7x56	5.6629	No	No	0	8	8
762	6x43	7x48	3.26772	No	No	0	7	6
763	6x54	7x34	3.49692	No	Yes	0	6	4
764	b.lhb1x10	b.lhb1x8	3.74035	No	No	0	4	2
765	b.l5x2	b.l8x10	3.50686	Yes	No	0	6	4
766	b.b8x1	b.b9x4	3.02708	No	No	0	8	9
767	b.b8x3	b.b9x4	2.70035	Yes	No	0	6	9
768	b.b15x5	b.l15x2	3.46522	No	Yes	4	8	9
769	b.l17x3	b.l19x2	3.22953	Yes	Yes	1	9	9
770	b.1x12	g.h1x11	3.41495	No	No	0	1	9
771	E2	Lig	12.6401	Yes	Yes	2	5	0
772	7x38	Lig	5.76209	No	Yes	2	7	0
773	b.l24x3	b.lhb1x3	3.63012	Yes	Yes	0	5	2
774	g.h1x10	g.h1x14	5.00796	No	No	0	9	9
775	E1x50	E2	3.12304	Yes	Yes	2	9	5
776	3x22	E2	7.76196	No	Yes	2	4	5
777	b.1x1	b.1x5	3.03191	Yes	No	0	0	0
778	b.1x13	b.1x9	3.05845	No	No	0	4	1
779	b.1x19	b.b21x1	8.06302	No	Yes	0	2	7
780	b.l5x4	b.l5x5	4.08714	No	Yes	0	8	9
781	3x50	G.H5.25	5.77736	Yes	Yes	2	9	7
782	b.1x13	b.1x16	3.86676	No	No	0	4	2
783	1x36	2x61	2.72666	No	No	0	5	7
784	3x30	4x62	4.57509	No	No	0	7	6
785	3x55	5x64	3.45278	No	No	0	8	6
786	E2	E2x52	5.7259	Yes	No	2	5	6
787	6x55	7x34	2.78406	No	Yes	2	8	4
788	G.HN.45	G.HN.49	3.15402	Yes	No	0	4	4
789	3x26	E2	4.24768	No	Yes	2	7	5
790	7x34	E2	5.27871	Yes	Yes	2	4	5
791	2x60	Lig	4.55368	No	Yes	0	7	0
792	1x39	2x57	4.09302	Yes	Yes	2	7	8
793	5x41	6x59	3.282	No	Yes	0	7	7
794	1x35	7x35	2.69199	Yes	No	2	5	6
795	1x35	7x39	3.03216	Yes	Yes	2	5	8
796	1x38	7x39	3.51219	No	Yes	0	5	8
797	1x39	7x42	3.89343	Yes	Yes	2	7	8
798	3x25	E2	3.53266	No	Yes	2	9	5
799	E2x51	Lig	4.40833	No	Yes	2	5	0
800	7x34	Lig	2.99052	Yes	Yes	2	4	0
801	b.l16x2	b.l16x3	3.04594	No	Yes	0	9	3
802	6x51	7x41	2.87153	Yes	No	0	8	8
803	NT	NT	7.68672	Yes	Yes	2	0	0
804	E2	NT	5.20348	Yes	Yes	2	5	0
805	Lig	NT	4.48119	Yes	Yes	2	0	0
806	3x29	4x65	3.85613	No	No	0	7	0
807	Lig	Lig	40.6664	Yes	Yes	2	0	0
808	1x42	7x43	2.65338	No	No	0	7	5
809	b.l1x4	b.l3x2	2.65007	No	Yes	0	6	9
810	b.b24x1	b.l25x5	2.6453	No	No	0	4	7
811	5x40	E2	2.62143	No	Yes	2	7	5
812	b.b15x1	b.l16x1	2.62049	Yes	No	0	9	4
813	b.b7x1	b.b9x1	2.60024	Yes	No	0	4	4
814	1x54	2x44	2.59995	No	No	0	7	6
815	G.S4.01	G.S5.03	2.59798	No	No	0	8	8
816	G.H5.07	G.S5.05	2.59552	No	Yes	0	8	9
817	3x53	G.H5.22	2.59284	No	No	0	8	4
818	b.b26x4	b.b2x5	2.58817	No	Yes	0	5	7
819	G.H5.15	G.H5.19	2.58612	No	No	0	7	8
820	b.b19x1	b.l18x1	2.58106	No	Yes	0	6	6
821	G.hgh4.01	G.s4h3.15	2.57258	No	No	0	6	9
822	G.H3.02	G.H4.15	2.55947	No	Yes	0	8	8
823	G.S4.03	G.S5.05	2.55811	No	Yes	0	7	9
824	b.lhb1x1	b.lhb1x2	2.55526	No	No	0	1	1
825	1x47	2x51	2.5521	No	Yes	0	7	8
826	2x42	4x45	2.54542	Yes	No	0	8	6
827	G.H4.01	G.HG.14	2.53589	No	No	0	3	5
828	b.h2x1	g.h2x5	2.52164	Yes	No	0	5	6
829	b.b27x4	b.b28x3	2.52082	No	Yes	0	5	7
830	1x29	1x32	2.51978	No	No	0	0	4
831	G.HN.42	G.HN.45	2.51875	No	Yes	0	4	4
832	2x43	7x54	2.51589	No	Yes	0	8	8
833	b.b5x3	b.l1x2	2.50851	Yes	No	0	9	9
834	1x31	7x32	2.49354	No	No	0	4	3
835	b.b18x2	b.b22x3	2.49319	No	No	0	5	6
836	G.S4.07	G.s5hg.01	2.48879	No	No	0	8	9
837	2x43	3x46	2.48734	No	Yes	0	8	9
838	b.b16x3	b.b19x2	2.47525	No	Yes	0	6	6
839	G.h2s4.01	G.h2s4.04	2.47455	Yes	No	0	9	9
840	g.ctx12	g.ctx13	2.46713	No	No	0	6	5
841	b.1x2	b.1x5	2.4598	No	No	0	0	0
842	8x47	8x49	2.45278	No	No	0	9	7
843	7x30	7x33	2.41638	Yes	No	0	7	6
844	b.b10x5	b.b6x4	2.41269	Yes	No	0	9	7
845	3x48	5x57	2.4105	No	No	0	6	7
846	1x45	7x47	2.40021	No	No	0	5	7
847	b.1x11	g.h1x12	2.3937	No	Yes	0	6	6
848	b.b24x2	b.l25x1	2.38055	No	No	0	5	3
849	2x59	E1x52	2.37106	No	Yes	0	6	7
850	b.l22x2	b.l27x4	2.36483	No	No	0	1	9
851	b.h2x5	g.h2x9	2.34746	Yes	No	0	5	4
852	1x53	2x47	2.34533	No	No	0	9	9
853	g.ctx7	g.ctx8	2.33789	No	No	0	4	8
854	4x65	E2x52	2.33715	No	No	0	0	6
855	b.h2x2	b.lh12x4	2.33237	No	No	0	1	3
856	G.H5.14	G.H5.18	2.29743	No	No	0	7	4
857	2x51	2x55	2.29403	Yes	No	0	8	6
858	b.b2x2	b.b6x3	2.28837	No	No	0	7	8
859	2x63	E1	2.27716	No	No	0	6	0
860	b.h2x4	g.h2x5	2.24889	No	No	0	3	6
861	3x52	3x56	2.23979	No	No	0	5	7
862	E2	E3	2.23905	Yes	Yes	2	5	4
863	b.h2x3	b.lh12x3	2.22816	No	No	0	1	4
864	b.b21x5	b.h2x2	2.22447	Yes	No	0	4	1
865	G.S2.02	G.S3.07	2.21384	No	Yes	0	5	9
866	5x62	6x37	2.20601	No	No	0	6	8
867	b.b18x5	b.l18x4	2.20513	Yes	No	0	5	7
868	G.H4.06	G.HG.04	2.18063	No	Yes	0	7	9
869	5x47	5x48	2.17605	Yes	No	0	8	7
870	b.l22x2	g.ctx2	2.17466	No	No	0	1	3
871	5x37	6x59	2.17436	No	Yes	0	4	7
872	G.HN.37	G.HN.41	2.16867	No	No	0	3	4
873	1x54	2x47	2.15897	No	No	0	7	9
874	I1x48	b.b28x2	2.1368	No	Yes	0	7	4
875	G.H1.01	G.s1h1.05	2.13038	Yes	No	0	9	9
876	6x32	G.H5.26	2.12501	No	Yes	0	8	5
877	b.b7x5	b.l7x1	2.11	No	No	0	9	9
878	b.l7x5	b.l9x1	2.10488	Yes	No	0	6	5
879	6x33	G.H5.25	2.10045	No	Yes	0	8	7
880	1x60	I1x49	2.09944	Yes	No	0	7	6
881	1x56	8x50	2.08864	No	Yes	0	8	8
882	b.b18x4	b.b22x5	2.08251	No	Yes	0	3	7
883	7x55	8x50	2.06945	Yes	Yes	0	6	8
884	G.HG.02	G.HG.03	2.0681	No	No	0	9	6
885	b.b28x1	b.b28x2	2.06569	No	Yes	0	4	4
886	G.HG.12	G.HG.13	2.06498	No	Yes	0	1	7
887	1x48	1x49	2.05072	No	No	0	4	9
888	6x34	6x38	2.04135	No	No	0	8	7
889	4x41	4x45	2.01785	No	No	0	7	6
890	b.b9x2	b.l12x1	2.01727	No	No	0	5	6
891	b.b1x3	g.ctx17	1.99427	No	Yes	0	7	7
892	6x42	6x46	1.98674	No	No	0	6	5
893	g.h2x14	g.h2x15	1.97861	No	No	0	4	6
894	8x50	8x54	1.97683	Yes	No	0	8	8
895	7x31	E2	1.96847	No	Yes	2	2	5
896	b.b25x4	b.lhb1x9	1.96808	No	No	0	4	3
897	5x44	5x45	1.96708	No	No	0	7	5
898	1x54	2x48	1.96323	No	No	0	7	7
899	b.l13x5	b.l15x2	1.95993	No	Yes	0	5	9
900	2x551	3x31	1.94165	No	No	0	6	5
901	b.l17x1	b.l17x2	1.92339	No	No	0	2	6
902	G.HN.11	G.HN.34	1.9142	Yes	No	0	2	3
903	g.h1x1	g.h1x5	1.90605	Yes	Yes	0	9	9
904	5x35	E2	1.89758	No	Yes	2	0	5
905	3x41	4x52	1.89685	No	No	0	7	5
906	I2x53	I2x54	1.89605	Yes	No	0	8	6
907	b.1x7	g.h1x8	1.88422	No	No	0	0	7
908	G.HN.43	b.b5x6	1.88221	No	No	0	9	6
909	G.S3.07	G.s3h2.01	1.8747	Yes	No	0	9	9
910	G.h4s6.04	G.h4s6.11	1.86866	No	Yes	0	4	7
911	G.hns1.03	I2x55	1.86307	Yes	No	0	4	5
912	b.b22x3	b.b23x2	1.85854	No	No	0	6	6
913	8x47	G.H5.24	1.85208	No	No	0	9	8
914	b.1x16	b.1x17	1.83733	No	No	0	2	4
915	G.s4h3.07	G.s4h3.15	1.83647	No	No	0	5	9
916	b.b13x1	b.l12x3	1.83045	No	No	0	4	5
917	G.HN.51	b.l1x4	1.82726	No	No	0	5	6
918	G.s6h5.02	G.s6h5.04	1.82604	No	No	0	7	8
919	b.1x10	b.1x6	1.82217	No	No	0	8	0
920	5x66	5x70	1.81514	No	No	0	7	6
921	G.S5.07	G.s1h1.06	1.80132	Yes	No	0	9	9
922	b.b28x6	b.l25x2	1.79659	Yes	No	0	9	5
923	b.b12x1	b.l13x5	1.79192	No	No	0	6	5
924	b.1x6	b.1x9	1.78824	No	No	0	0	1
925	b.1x15	g.h1x15	1.78057	No	No	0	4	8
926	1x59	1x60	1.77865	Yes	Yes	0	6	7
927	7x51	7x55	1.77199	No	Yes	0	6	6
928	b.b25x5	b.lhb1x8	1.76955	No	No	0	4	2
929	b.1x18	g.l1x4	1.76725	No	Yes	0	6	8
930	g.h1x12	g.h1x8	1.76679	Yes	No	0	6	7
931	b.1x22	g.l1x4	1.76325	No	Yes	0	0	8
932	7x30	E3	1.7492	Yes	Yes	2	7	4
933	b.1x11	b.1x14	1.74409	No	No	0	6	7
934	b.1x1	g.h1x1	1.72908	Yes	Yes	0	0	9
935	b.1x4	g.h1x4	1.72545	No	No	0	0	1
936	b.b17x2	g.h1x13	1.71564	No	No	0	3	1
937	b.l8x4	b.l8x5	1.7029	No	Yes	0	3	3
938	b.b12x6	b.l9x2	1.70217	Yes	No	0	8	5
939	G.HN.45	G.HN.48	1.69568	Yes	No	0	4	3
940	G.H1.03	G.H1.07	1.69086	No	No	0	9	9
941	b.l13x1	b.l13x2	1.6811	No	No	0	2	6
942	7x24	NT	1.67397	No	Yes	0	0	0
943	b.b16x2	b.l17x1	1.67074	No	No	0	5	2
944	2x41	4x43	1.66002	No	No	0	6	4
945	g.h1x12	g.h1x9	1.64487	Yes	No	0	6	6
946	G.H3.01	G.s4h3.08	1.64236	Yes	No	0	9	8
947	5x46	5x461	1.64061	No	No	0	5	8
948	5x69	G.H5.13	1.63694	No	Yes	0	6	8
949	1x40	2x61	1.63052	No	No	0	4	7
950	6x39	7x52	1.62928	No	No	0	7	8
951	6x43	7x52	1.62587	No	No	0	7	8
952	4x38	4x40	1.61524	No	No	0	8	6
953	5x64	5x67	1.61019	No	No	0	6	6
954	b.1x4	g.h1x5	1.60804	No	Yes	0	0	9
955	1x27	2x67	1.60762	No	No	0	0	5
956	5x60	5x63	1.5979	No	No	0	7	5
957	G.hns1.03	I2x54	1.58948	Yes	No	0	4	6
958	1x32	2x64	1.58252	No	Yes	0	4	7
959	4x56	5x42	1.57547	No	No	0	8	5
960	6x25	6x26	1.57522	No	No	0	4	5
961	G.s1h1.02	G.s1h1.05	1.5604	No	No	0	7	9
962	1x36	2x65	1.55565	No	No	0	5	6
963	4x63	E2	1.55436	No	Yes	2	5	5
964	3x21	3x24	1.52323	No	No	0	7	6
965	3x23	3x26	1.51759	No	No	0	4	7
966	b.b21x7	b.l24x1	1.49739	Yes	No	0	5	5
967	b.1x12	b.1x15	1.49073	No	No	0	1	4
968	G.HG.05	G.HG.06	1.48183	No	No	0	5	5
969	6x57	E3	1.48036	No	Yes	0	6	4
970	2x41	4x39	1.47214	No	No	0	6	5
971	b.b20x1	b.l21x5	1.46499	No	No	0	5	4
972	7x55	8x51	1.45975	Yes	No	0	6	9
973	1x36	1x37	1.43864	No	No	0	5	4
974	b.h2x4	g.h2x2	1.43287	No	No	0	3	9
975	2x44	I1	1.42905	No	No	0	6	0
976	g.h1x10	g.h1x6	1.42464	No	No	0	9	8
977	6x59	6x60	1.41555	Yes	Yes	0	7	5
978	G.H3.03	G.H3.07	1.40734	No	No	0	4	5
979	6x49	6x53	1.40119	Yes	No	0	7	7
980	3x27	3x31	1.40001	No	No	0	5	5
981	G.HG.05	G.HG.09	1.38268	No	No	0	5	2
982	5x69	6x30	1.38209	No	No	0	6	8
983	5x34	NT	1.37413	No	Yes	0	0	0
984	1x41	1x45	1.37141	No	No	0	4	5
985	G.H5.01	G.s6h5.05	1.36542	No	No	0	9	9
986	G.HN.50	G.HN.53	1.36158	No	No	0	5	1
987	g.ctx6	g.ctx7	1.3523	Yes	No	0	6	4
988	b.1x7	g.h1x7	1.3428	No	No	0	0	2
989	1x49	7x50	1.34013	No	No	0	9	9
990	g.h1x5	g.h1x9	1.32288	Yes	No	0	9	6
991	1x59	8x57	1.32237	Yes	No	0	6	7
992	1x58	1x59	1.316	No	Yes	0	4	6
993	1x30	1x31	1.31121	No	No	0	0	4
994	7x32	7x36	1.3058	No	No	0	3	4
995	b.1x3	b.1x7	1.29964	No	No	0	0	0
996	1x44	1x48	1.29649	No	No	0	4	4
997	G.H1.05	G.S2.04	1.29003	No	No	0	6	6
998	7x36	7x39	1.28911	No	Yes	0	4	8
999	G.HN.52	G.hns1.03	1.27032	No	Yes	0	4	4
1000	5x32	E2	1.26258	No	Yes	0	0	5
1001	5x68	5x71	1.25602	No	No	0	7	5
1002	G.H3.04	G.H3.07	1.24799	No	No	0	9	5
1003	7x27	Lig	1.24679	No	Yes	0	0	0
1004	6x27	6x30	1.24406	No	No	0	5	8
1005	1x51	2x51	1.22406	No	Yes	0	5	8
1006	b.l2x2	b.l6x2	1.20972	No	No	0	1	6
1007	8x48	8x52	1.19133	No	No	0	6	6
1008	g.h1x1	g.h1x3	1.18615	Yes	No	0	9	6
1009	b.ntx3	g.h1x1	1.17402	No	Yes	0	0	9
1010	7x25	7x28	1.16315	No	No	0	0	0
1011	7x26	E3	1.16281	No	Yes	0	0	4
1012	b.lhb1x6	b.lhb1x7	1.16239	Yes	No	0	3	1
1013	8x56	b.l25x4	1.16229	No	No	0	6	5
1014	G.HN.45	G.HN.46	1.16001	Yes	No	0	4	4
1015	G.H4.13	G.H4.17	1.13297	No	No	0	3	4
1016	b.1x16	b.1x20	1.11586	No	No	0	2	3
1017	g.h1x12	g.l1x1	1.1107	Yes	No	0	6	1
1018	b.b16x1	b.l17x3	1.10918	No	Yes	0	4	9
1019	5x33	6x59	1.10125	No	Yes	0	0	7
1020	b.1x12	b.1x9	1.0993	No	No	0	1	1
1021	7x23	7x25	1.09629	No	No	0	0	0
1022	G.H1.06	G.H1.09	1.08642	No	Yes	0	9	7
1023	6x38	6x42	1.07572	No	No	0	7	6
1024	6x35	6x39	1.07457	No	No	0	7	7
1025	G.HN.44	G.HN.48	1.07195	No	No	0	6	3
1026	5x35	6x62	1.05354	No	No	0	0	0
1027	1x26	7x31	1.04286	No	No	0	0	2
1028	1x28	1x31	1.04213	No	No	0	0	4
1029	5x411	6x60	1.03143	No	Yes	0	0	5
1030	6x31	6x35	1.02076	No	No	0	6	7
1031	6x26	G.h4s6.12	1.01827	No	Yes	0	5	4
1032	G.H1.09	G.S2.04	1.01228	Yes	No	0	7	6
1033	G.s1h1.02	G.s1h1.03	1.00913	No	No	0	7	8
1034	b.1x8	g.h1x8	0.990468	No	No	0	0	7
1035	4x40	4x44	0.982007	No	No	0	6	3
1036	1x27	E2	0.97746	No	Yes	2	0	5
1037	G.H1.02	G.H1.03	0.972823	No	No	0	9	9
1038	G.s4h3.08	G.s4h3.10	0.972789	No	No	0	8	0
1039	g.ctx17	g.ctx18	0.96166	Yes	No	0	7	0
1040	5x72	G.H5.13	0.960371	No	Yes	0	0	8
1041	1x29	1x33	0.960315	No	No	0	0	5
1042	G.HN.36	b.b5x2	0.941808	No	Yes	0	4	7
1043	b.lhb1x3	g.h2x13	0.920909	Yes	No	0	2	1
1044	6x60	6x64	0.91252	Yes	No	0	5	0
1045	5x31	E2	0.896573	No	Yes	0	0	5
1046	g.ctx6	g.h2x16	0.881111	Yes	No	0	6	4
1047	g.ctx11	g.ctx17	0.845739	No	Yes	0	4	7
1048	G.h2s4.02	G.h2s4.03	0.845534	No	No	0	7	5
1049	G.H2.01	b.l9x4	0.844305	No	No	0	9	5
1050	G.s3h2.01	G.s3h2.02	0.842839	No	No	0	9	9
1051	b.1x2	b.ntx2	0.841193	No	No	0	0	0
1052	5x55	5x59	0.829479	No	No	0	6	3
1053	1x25	E2	0.824286	No	Yes	0	0	5
1054	b.l8x3	b.l8x6	0.816446	No	No	0	3	4
1055	G.s4h3.11	G.s4h3.13	0.814948	No	No	0	0	0
1056	4x54	4x58	0.813663	No	No	0	5	6
1057	8x51	8x55	0.813475	No	No	0	9	6
1058	1x26	7x28	0.806042	No	No	0	0	0
1059	G.H3.04	G.s4h3.14	0.791972	No	No	0	9	0
1060	4x48	4x52	0.774931	No	No	0	3	5
1061	b.1x1	g.ntx4	0.772003	Yes	No	0	0	0
1062	G.HN.30	G.HN.32	0.747169	No	No	0	7	5
1063	1x61	2x40	0.740556	No	Yes	0	0	9
1064	5x51	5x52	0.712531	No	No	0	7	5
1065	G.HN.51	G.hns1.01	0.70085	No	No	0	5	3
1066	6x28	6x31	0.689061	No	No	0	5	6
1067	4x48	4x51	0.668832	No	No	0	3	5
1068	G.s4h3.11	G.s4h3.14	0.650104	No	No	0	0	0
1069	G.HN.38	G.HN.42	0.57677	No	No	0	3	4
1070	b.lhb1x2	b.lhb1x3	0.568004	No	Yes	0	1	2
1071	G.HN.11	G.HN.37	0.563302	Yes	No	0	2	3
1072	b.l21x2	b.l21x3	0.530393	Yes	No	0	4	3
1073	1x34	7x36	0.516858	No	No	0	3	4
1074	G.s4h3.11	G.s4h3.12	0.516218	No	No	0	0	0
1075	G.s6h5.03	G.s6h5.04	0.509606	No	No	0	9	8
1076	G.H1.09	G.H1.10	0.502812	Yes	No	0	7	8
1077	G.H4.14	G.H4.17	0.487812	No	No	0	5	4
1078	g.h1x2	g.h1x5	0.48395	No	Yes	0	9	9
1079	b.1x1	g.ntx1	0.463095	Yes	No	0	0	0
1080	b.1x21	g.l1x6	0.388981	No	No	0	3	4
1081	G.s4h3.09	G.s4h3.10	0.386768	No	No	0	0	0
1082	4x54	4x55	0.38607	No	No	0	5	5
1083	6x23	G.h4s6.12	0.368591	No	Yes	0	4	4
1084	E1x501	NT	0.365976	No	Yes	0	0	0
1085	6x60	6x63	0.354298	Yes	No	0	5	0
1086	G.HN.10	G.HN.11	0.336662	No	Yes	0	4	2
1087	G.s2s3.02	I2x55	0.326881	No	No	0	3	5
1088	2x38	I2x58	0.325839	No	No	0	7	0
1089	7x29	7x30	0.325421	No	Yes	0	0	7
1090	5x29	E2	0.323956	No	Yes	2	0	5
1091	4x46	4x47	0.302828	No	No	0	8	5
1092	G.HN.09	G.HN.10	0.295621	No	No	0	0	4
1093	g.h2x6	g.h2x9	0.287531	No	No	0	2	4
1094	8x54	8x58	0.282668	No	No	0	8	7
1095	4x65	4x66	0.278857	No	No	0	0	0
1096	8x60	8x61	0.277512	No	No	0	0	0
1097	g.h3x11	g.h3x15	0.27419	No	No	0	0	0
1098	6x24	6x25	0.273161	No	No	0	5	4
1099	G.HN.31	G.HN.32	0.26289	No	No	0	1	5
1100	G.HN.35	G.HN.38	0.253925	No	No	0	4	3
1101	2x40	I1x52	0.250659	Yes	No	0	9	0
1102	b.l4x2	g.ctx21	0.250571	Yes	No	0	4	0
1103	g.l1x2	g.l1x3	0.237885	No	No	0	2	1
1104	b.1x3	b.ntx1	0.228516	No	No	0	0	0
1105	g.h3x6	g.h3x9	0.228434	No	No	0	0	0
1106	1x24	7x28	0.225714	No	No	0	0	0
1107	4x36	G.HN.52	0.218057	No	No	0	0	4
1108	4x40	I2	0.203341	No	No	0	6	0
1109	G.H1.11	G.S2.05	0.185557	No	Yes	0	0	3
1110	1x57	7x62	0.178857	No	No	0	8	0
1111	7x61	7x62	0.173429	No	No	0	0	0
1112	7x60	7x63	0.171714	No	No	0	0	0
1113	8x57	8x60	0.169661	No	No	0	7	0
1114	b.l20x2	g.h3x7	0.166978	Yes	No	0	9	0
1115	b.l22x3	g.l3x4	0.161827	No	No	0	9	0
1116	b.l18x3	g.h3x11	0.161367	Yes	No	0	5	0
1117	5x69	5x73	0.161364	No	No	0	6	0
1118	b.l18x1	g.h3x8	0.157967	Yes	No	0	6	0
1119	g.h1x1	g.ntx2	0.148484	Yes	No	0	9	0
1120	b.l21x6	b.l21x7	0.143335	No	No	0	3	5
1121	G.hgh4.06	G.hgh4.07	0.143254	No	No	0	3	7
1122	g.h2x10	g.h2x13	0.135282	No	No	0	3	1
1123	b.b20x7	g.h3x4	0.129299	Yes	No	0	9	0
1124	6x32	7x58	0.128571	No	No	0	8	0
1125	g.h3x10	g.h3x6	0.128482	No	No	0	0	0
1126	b.l24x2	g.h3x12	0.117685	Yes	No	0	6	0
1127	5x29	5x30	0.116734	No	No	0	0	0
1128	G.hns1.02	I2x56	0.110965	No	No	0	4	5
1129	G.H4.04	G.H4.08	0.109481	No	No	0	4	3
1130	5x24	5x27	0.107607	No	No	0	0	0
1131	G.H1.11	G.H1.12	0.101978	No	No	0	0	0
1132	g.h3x14	g.h3x15	0.098228	No	No	0	0	0
1133	b.lhb1x3	g.h3x13	0.0975893	Yes	No	0	2	0
1134	6x20	6x23	0.0960992	No	No	0	4	4
1135	G.hfs2.04	G.hfs2.05	0.0938393	No	No	0	0	0
1136	g.h3x1	g.l3x4	0.0928846	No	No	0	0	0
1137	g.ntx1	g.ntx3	0.0926738	No	No	0	0	0
1138	7x54	7x60	0.0926217	Yes	No	0	8	0
1139	g.h3x3	g.l3x4	0.0922527	No	No	0	0	0
1140	5x70	5x74	0.0920952	No	No	0	6	0
1141	1x60	CT	0.0916955	Yes	No	0	7	0
1142	6x65	7x30	0.0869643	No	Yes	0	0	7
1143	2x36	G.H5.22	0.086044	No	No	0	0	4
1144	4x68	E2	0.0859048	No	Yes	2	0	5
1145	5x28	E2	0.0779243	No	Yes	2	0	5
1146	7x55	I4	0.0748571	Yes	No	0	6	0
1147	b.h2x1	g.h3x5	0.074114	Yes	No	0	5	0
1148	b.b17x5	g.l2x1	0.0713393	Yes	No	0	7	0
1149	H.HC.11	H.HD.04	0.0695238	No	No	0	8	6
1150	b.1x1	g.ntx8	0.0666881	Yes	No	0	0	0
1151	b.lh12x2	g.h3x2	0.0657143	No	No	0	8	0
1152	4x34	4x37	0.0639429	No	No	0	0	0
1153	b.b21x1	g.l2x3	0.0638393	Yes	No	0	7	0
1154	7x58	7x59	0.0628603	No	No	0	0	0
1155	7x57	7x58	0.0602857	No	No	0	0	0
1156	E1x48	NT	0.0591429	No	Yes	0	0	0
1157	b.h2x5	g.h3x9	0.0586744	Yes	No	0	5	0
1158	5x75	G.H5.09	0.0582024	No	No	0	0	4
1159	7x64	I4	0.0557143	No	No	0	0	0
1160	G.hfs2.04	b.l7x5	0.0554281	No	Yes	0	0	6
1161	8x56	8x59	0.054	No	No	0	6	0
1162	g.h1x1	g.ntx6	0.0500298	Yes	No	0	9	0
1163	4x63	4x67	0.0499048	No	No	0	5	0
1164	5x25	5x26	0.0499023	No	No	0	0	0
1165	G.HN.02	G.HN.11	0.0489093	No	Yes	0	0	2
1166	2x64	E1x47	0.0486191	Yes	No	0	7	0
1167	6x19	6x23	0.0483175	No	No	0	5	4
1168	H.HA.17	b.b9x2	0.0482222	No	No	0	5	5
1169	2x34	2x36	0.0475824	No	No	0	0	0
1170	g.ctx17	g.ctx19	0.0464534	Yes	No	0	7	0
1171	H.HE.08	H.HE.11	0.0453651	No	No	0	5	8
1172	G.HN.08	G.HN.11	0.0446962	No	Yes	0	0	2
1173	1x23	1x24	0.0446154	No	No	0	0	0
1174	b.l20x2	g.l2x4	0.0442857	Yes	No	0	9	0
1175	5x25	5x28	0.0439927	No	No	0	0	0
1176	5x27	E2	0.0427106	No	Yes	2	0	5
1177	H.HE.04	H.HF.06	0.0424762	No	Yes	0	9	6
1178	6x20	6x21	0.0410714	No	No	0	4	5
1179	8x58	8x62	0.0402857	No	No	0	7	0
1180	H.HA.23	H.HB.08	0.0392064	No	No	0	4	1
1181	3x49	R:R:L77	0.0378571	Yes	No	0	9	0
1182	2x35	G.H5.19	0.0377473	No	No	0	0	8
1183	8x60	8x63	0.0374286	No	No	0	0	0
1184	4x34	G.hns1.03	0.0369714	No	Yes	0	0	4
1185	b.l22x5	g.l3x1	0.0352679	Yes	No	0	9	0
1186	H.HC.08	H.HE.10	0.0351111	No	No	0	3	3
1187	4x68	4x69	0.0350476	No	No	0	0	0
1188	H.HA.12	H.hbhc.14	0.0342222	No	No	0	4	3
1189	H.HD.07	H.HD.11	0.0339365	Yes	No	0	5	6
1190	G.S2.02	G.hfs2.02	0.0332064	No	No	0	5	0
1191	g.l3x1	g.l3x2	0.033125	No	No	0	0	0
1192	H.HA.11	H.HF.03	0.0324444	No	No	0	8	9
1193	6x461	6x47	0.0321786	No	No	0	0	8
1194	H.HA.03	H.HA.07	0.0320635	No	No	0	8	5
1195	H.HA.24	H.HA.28	0.0304762	No	No	0	3	3
1196	H.HB.04	H.HC.10	0.0301587	No	No	0	1	7
1197	H.hbhc.04	b.l8x9	0.0295238	No	No	0	3	3
1198	H.HF.03	H.hehf.04	0.0292063	No	No	0	9	8
1199	g.l3x2	g.l3x3	0.0291964	No	No	0	0	0
1200	G.H5.21	G.H5.27	0.028254	No	No	0	5	0
1201	H.HA.19	H.HC.07	0.0280317	Yes	Yes	15	6	6
1202	b.1x4	b.ntx4	0.0263516	No	No	0	0	0
1203	H.HE.04	H.HE.08	0.0255556	No	No	0	9	5
1204	H.HA.17	H.hdhe.04	0.0251429	No	No	0	5	6
1205	H.HB.07	H.HC.06	0.0249206	No	No	0	2	5
1206	H.HA.28	H.hdhe.01	0.0228571	No	Yes	0	3	6
1207	G.h1ha.05	H.HA.03	0.0228254	No	No	0	0	8
1208	H.HA.22	H.HE.06	0.0226667	No	Yes	0	7	7
1209	6x18	6x22	0.0222222	No	No	0	3	6
1210	H.HB.10	H.HC.02	0.0222222	No	No	0	1	3
1211	6x14	6x15	0.0221905	No	No	0	1	5
1212	G.H1.11	H.HF.01	0.0217778	No	No	0	0	5
1213	G.H1.10	G.h1ha.01	0.0216825	No	No	0	8	0
1214	H.HC.11	H.HE.09	0.0216825	No	No	0	8	5
1215	6x15	6x18	0.021619	No	No	0	5	3
1216	H.HB.04	H.hahb.08	0.0211111	No	No	0	1	2
1217	H.HF.02	H.HF.05	0.0211111	No	No	0	6	8
1218	H.hehf.01	H.hehf.03	0.0209524	No	No	0	1	3
1219	H.HD.10	H.hdhe.01	0.0201905	No	Yes	0	6	6
1220	H.HA.07	H.HF.04	0.0200317	No	No	0	5	8
1221	H.HA.26	H.HD.03	0.0193333	No	No	0	7	6
1222	H.HA.15	H.HE.12	0.0193016	No	No	0	5	7
1223	H.HD.08	H.HD.11	0.0191429	No	No	0	2	6
1224	H.HA.18	H.HE.06	0.0190794	No	Yes	0	7	7
1225	6x22	6x26	0.0188571	No	No	0	6	5
1226	H.HA.20	H.HA.23	0.0186984	No	No	0	5	4
1227	H.HD.03	H.hchd.01	0.0185397	No	No	0	6	8
1228	H.HA.14	H.HE.05	0.0184444	No	Yes	0	9	7
1229	H.HA.16	H.hbhc.04	0.0173651	No	No	0	4	3
1230	6x17	G.H4.17	0.0151111	No	No	0	3	4
1231	g.ntx4	g.ntx5	0.015	No	No	0	0	0
1232	H.hbhc.03	b.l8x4	0.0147619	No	No	0	3	3
1233	H.HA.19	H.HB.11	0.0146349	Yes	No	0	6	1
1234	H.HA.05	H.HA.08	0.0136825	No	No	0	2	5
1235	H.HA.26	H.hahb.08	0.0132063	No	No	0	7	2
1236	H.HE.05	H.HF.06	0.0130794	Yes	Yes	0	7	6
1237	H.HE.01	H.HF.06	0.0125397	No	Yes	0	8	6
1238	6x15	6x16	0.0125079	No	No	0	5	3
1239	H.HA.10	b.l5x2	0.0124444	No	Yes	0	5	6
1240	H.HA.04	H.hehf.06	0.0119683	No	No	0	6	9
1241	g.h1x1	g.ntx7	0.0112747	Yes	No	0	9	0
1242	H.hehf.05	H.hehf.06	0.0107619	No	No	0	3	9
1243	4x41	I2x59	0.0104464	No	No	0	7	0
1244	H.hbhc.12	b.l8x5	0.010381	No	Yes	0	1	3
1245	H.hehf.01	H.hehf.02	0.0100317	No	No	0	1	1
1246	H.HD.02	H.hahb.06	0.00955555	No	No	0	4	4
1247	5x75	5x76	0.00952381	No	No	0	0	0
1248	H.HC.03	H.hbhc.15	0.00936508	Yes	No	0	3	3
1249	H.HE.12	H.hbhc.14	0.00926984	No	No	0	7	3
1250	H.HF.02	H.hehf.07	0.00898413	No	No	0	6	6
1251	G.h1ha.04	H.hehf.06	0.0088254	No	No	0	0	9
1252	H.HB.03	H.HB.07	0.00879365	No	No	0	3	2
1253	H.HD.07	H.HE.03	0.00879365	Yes	No	0	5	3
1254	1x22	E3	0.00868132	No	Yes	0	0	4
1255	H.HA.29	H.hahb.05	0.00860317	No	No	0	6	2
1256	H.HA.25	H.hdhe.01	0.00847619	No	Yes	0	7	6
1257	H.HB.10	H.HC.06	0.00831746	No	No	0	1	5
1258	H.HB.05	H.HB.08	0.00828571	No	No	0	3	1
1259	H.HA.18	H.HE.05	0.00806349	No	Yes	0	7	7
1260	H.HA.11	H.HE.05	0.008	No	Yes	0	8	7
1261	H.HA.15	H.HE.05	0.00793651	No	Yes	0	5	7
1262	g.ctx20	g.ctx21	0.00787302	No	No	0	0	0
1263	g.h3x3	g.l2x5	0.00774725	No	No	0	0	0
1264	H.HB.10	H.HC.03	0.00774603	No	Yes	0	1	3
1265	H.HD.07	H.hdhe.03	0.00774603	Yes	No	0	5	7
1266	H.HD.07	H.HE.06	0.00774603	Yes	Yes	0	5	7
1267	H.HB.07	H.HC.10	0.00771429	No	No	0	2	7
1268	H.hahb.06	H.hahb.08	0.0075873	No	No	0	4	2
1269	H.HA.06	b.l5x2	0.00742857	No	Yes	0	4	6
1270	H.hdhe.01	H.hdhe.03	0.00742857	Yes	No	0	6	7
1271	H.HF.02	H.HF.06	0.00742857	No	Yes	0	6	6
1272	H.HC.11	H.HE.07	0.0071746	No	No	0	8	4
1273	H.hdhe.01	b.b13x2	0.00714286	Yes	No	0	6	4
1274	H.HC.04	H.HE.13	0.00568254	No	No	0	4	4
1275	H.HC.05	H.HC.08	0.00552381	No	No	0	1	3
1276	H.HD.06	H.HD.10	0.00546032	No	No	0	5	6
1277	H.HA.27	H.HA.29	0.00542857	No	No	0	1	6
1278	H.HB.14	H.HC.03	0.00542857	No	Yes	0	3	3
1279	H.HA.27	H.HB.08	0.00520635	No	No	0	1	1
1280	G.hfs2.03	H.HE.01	0.00514286	No	No	0	0	8
1281	G.H1.09	G.h1ha.02	0.00511111	Yes	No	0	7	0
1282	H.HC.04	H.hbhc.14	0.00511111	No	No	0	4	3
1283	G.hfs2.01	H.HA.10	0.00504762	No	No	0	0	5
1284	G.hfs2.01	H.HF.04	0.00504762	No	No	0	0	8
1285	H.HA.21	H.hdhe.03	0.00501587	No	No	0	4	7
1286	H.HE.02	H.HE.06	0.00501587	No	Yes	0	7	7
1287	H.HE.03	H.HE.07	0.00495238	No	No	0	3	4
1288	H.HA.20	H.HB.11	0.00488889	No	No	0	5	1
1289	H.HA.22	H.HD.03	0.00488889	No	No	0	7	6
1290	H.HB.05	H.HB.06	0.00488889	No	No	0	3	4
1291	H.hehf.05	H.hehf.07	0.0048254	No	No	0	3	6
1292	H.hahb.06	H.hahb.07	0.00479365	No	No	0	4	3
1293	H.hbhc.01	H.hbhc.04	0.00479365	No	No	0	2	3
1294	H.hbhc.12	H.hbhc.13	0.00479365	No	No	0	1	1
1295	H.hahb.09	H.hchd.01	0.00466667	No	No	0	1	8
1296	H.HA.19	H.HC.03	0.00453968	Yes	Yes	15	6	3
1297	H.HA.19	H.HE.09	0.00453968	Yes	No	15	6	5
1298	H.HC.03	H.HC.07	0.00453968	Yes	Yes	15	3	6
1299	H.HC.07	H.HC.10	0.00453968	Yes	No	0	6	7
1300	H.HC.07	H.HE.09	0.00453968	Yes	No	15	6	5
1301	H.HE.10	H.HE.11	0.00377778	No	No	0	3	8
1302	H.hdhe.01	H.hdhe.02	0.0035873	Yes	No	0	6	8
1303	G.HN.29	G.HN.30	0.00197802	No	No	0	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.11	1.05289	6	0	2
2	G.HN.45	2.13212	4	0	4
3	G.hns1.03	1.18996	4	0	4
4	G.S1.02	4.75724	5	7	5
5	G.H1.01	4.33967	4	17	9
6	G.H1.09	0.651657	4	0	7
7	G.S2.03	4.41711	4	1	9
8	G.S2.05	4.69393	4	1	3
9	G.S2.08	7.62142	4	7	5
10	G.S3.01	4.46941	4	7	4
11	G.S3.03	7.54913	5	7	7
12	G.S3.04	7.08254	4	1	6
13	G.S3.06	7.45084	5	1	5
14	G.S3.07	3.54785	4	17	9
15	G.s3h2.03	3.9755	5	1	9
16	G.H2.06	4.76918	7	1	9
17	G.H2.07	4.24792	6	1	9
18	G.H2.09	5.83568	4	1	8
19	G.h2s4.01	5.89719	5	1	9
20	G.S4.04	5.38895	5	6	9
21	G.s4h3.04	5.5338	6	9	8
22	G.s4h3.05	5.94523	4	9	9
23	G.H3.01	5.15384	4	0	9
24	G.H3.09	5.04597	7	6	9
25	G.H3.13	3.66027	4	6	5
26	G.H3.17	6.69607	6	1	5
27	G.H3.18	5.47007	4	16	9
28	G.S5.04	3.78737	5	6	9
29	G.S5.05	3.38403	7	12	9
30	G.S5.07	3.61841	4	0	9
31	G.HG.04	4.73913	5	9	9
32	G.HG.13	3.05979	4	9	7
33	G.hgh4.02	5.60858	6	18	7
34	G.hgh4.05	8.0357	4	0	7
35	G.H4.03	6.13004	4	0	4
36	G.H4.15	4.46883	5	6	8
37	G.h4s6.02	4.86889	4	6	8
38	G.h4s6.11	4.00383	4	6	7
39	G.h4s6.12	4.34759	4	0	4
40	G.S6.02	6.78379	4	0	7
41	G.H5.03	5.28252	4	12	8
42	G.H5.08	5.72121	4	7	8
43	G.H5.13	2.99875	6	0	8
44	G.H5.20	3.71618	4	0	9
45	G.H5.25	3.37339	4	2	7
46	G.H5.26	4.56876	5	0	5
47	g.h1x1	0.886442	7	0	9
48	g.h1x5	1.33023	4	0	9
49	g.l1x4	4.52962	4	0	8
50	g.h2x11	8.24273	4	10	6
51	g.ctx3	6.07968	5	8	9
52	g.ctx5	2.84901	4	8	9
53	g.ctx6	3.43494	5	8	6
54	g.ctx14	4.64309	4	3	9
55	g.ctx15	5.92089	4	3	9
56	g.ctx16	4.24923	8	3	8
57	g.ctx17	0.96203	4	0	7
58	1x35	3.58552	4	2	5
59	1x39	4.10732	5	2	7
60	1x50	5.53963	4	0	9
61	1x59	2.09407	4	0	6
62	1x60	2.13557	5	0	7
63	2x40	2.68024	5	0	9
64	2x42	3.30266	6	0	8
65	2x46	4.22545	4	2	9
66	2x50	5.80914	5	2	9
67	2x51	2.56569	4	0	8
68	2x57	4.54893	4	2	8
69	2x64	2.0134	4	2	7
70	E1x50	5.69617	5	2	9
71	E1x52	4.87785	4	0	7
72	3x37	3.55876	4	0	8
73	3x43	4.03138	4	2	8
74	3x46	3.60115	4	2	9
75	3x49	3.43123	5	20	9
76	3x50	5.28174	5	2	9
77	I2x53	4.10594	4	20	8
78	E2	6.5077	28	2	5
79	5x47	4.7047	5	2	8
80	5x58	4.90719	5	0	9
81	6x44	4.05448	5	2	9
82	6x48	5.40757	7	2	8
83	6x49	2.62446	4	0	7
84	6x51	4.04862	5	2	8
85	6x59	2.17695	5	0	7
86	6x60	0.92845	4	0	5
87	E3	3.37503	9	2	4
88	7x30	1.14449	4	2	7
89	7x34	3.63755	4	2	4
90	7x39	2.92946	4	2	8
91	7x42	4.46066	5	2	8
92	7x49	5.75001	4	2	9
93	7x53	4.66204	5	2	9
94	7x54	2.28502	4	0	8
95	7x55	1.34401	4	0	6
96	8x50	2.76691	6	0	8
97	Lig	9.57331	17	2	0
98	b.h2x1	2.99076	5	0	5
99	b.h2x5	2.568	4	0	5
100	b.lhb1x3	1.86612	5	0	2
101	b.lhb1x6	3.85294	4	8	3
102	b.b1x6	7.3762	4	3	9
103	b.l1x3	7.9934	6	3	9
104	b.b2x1	7.6079	5	1	8
105	b.b2x5	6.32366	6	3	7
106	b.l3x2	4.74949	5	3	9
107	b.b4x2	4.73174	4	0	8
108	b.b4x3	4.27635	4	5	7
109	b.b4x5	4.15331	4	5	7
110	b.b4x6	8.56794	7	3	9
111	b.l4x2	9.70073	4	3	4
112	b.b5x2	5.45375	4	0	7
113	b.b5x3	6.12188	6	3	9
114	b.b5x5	4.89921	4	5	5
115	b.b5x7	5.24715	4	0	7
116	b.l5x1	3.94158	5	5	8
117	b.l5x2	2.65676	4	0	6
118	b.l5x5	6.7566	7	1	9
119	b.b6x5	3.76866	7	5	6
120	b.l6x5	5.8158	4	13	4
121	b.b7x1	5.40273	5	13	4
122	b.b7x4	3.46218	4	5	8
123	b.l7x2	3.56099	5	1	9
124	b.l7x4	3.77053	4	0	9
125	b.l7x5	2.84752	4	0	6
126	b.b8x3	3.40596	4	0	6
127	b.b8x4	4.67456	6	5	6
128	b.l8x5	1.89881	4	0	3
129	b.l9x3	6.84924	6	1	9
130	b.l9x6	4.368	9	1	8
131	b.b10x5	4.16942	6	0	9
132	b.b11x4	5.04547	5	1	9
133	b.l11x2	7.73782	4	1	9
134	b.b12x6	7.67175	7	1	8
135	b.b12x7	5.02196	4	21	9
136	b.b13x7	7.36812	5	4	7
137	b.l13x3	7.26796	6	4	9
138	b.l13x6	4.48025	5	1	9
139	b.l13x7	4.59328	4	4	9
140	b.b14x3	4.0672	4	4	5
141	b.b15x1	6.4642	5	4	9
142	b.b15x2	5.90536	4	1	6
143	b.b15x3	4.58695	4	4	9
144	b.l15x1	5.26198	4	1	7
145	b.l15x2	5.08136	5	4	9
146	b.b16x4	10.0296	4	4	6
147	b.b16x5	4.41542	4	0	5
148	b.b16x6	8.27588	6	4	8
149	b.l16x3	4.73153	4	22	3
150	b.b17x5	5.96561	4	1	7
151	b.b17x7	7.7917	4	1	8
152	b.l17x3	8.49874	6	1	9
153	b.l17x6	5.74377	5	1	9
154	b.b18x3	4.93323	4	1	8
155	b.b18x5	4.97939	4	0	5
156	b.l18x1	5.25069	8	10	6
157	b.l18x2	5.78063	4	10	7
158	b.l18x3	6.28075	4	10	5
159	b.b19x2	6.44538	6	1	6
160	b.b19x4	6.11983	4	1	8
161	b.l19x2	5.95653	5	1	9
162	b.b20x4	10.1299	5	1	8
163	b.b20x6	7.1599	5	1	6
164	b.b20x7	3.6922	4	0	9
165	b.l20x2	4.48753	5	0	9
166	b.b21x1	6.79386	5	1	7
167	b.b21x5	4.98038	4	0	4
168	b.b21x7	5.17518	6	0	5
169	b.l21x2	4.35718	4	0	4
170	b.b22x5	5.22141	5	10	7
171	b.l22x5	5.54137	7	8	9
172	b.b23x6	6.9122	6	14	7
173	b.l23x1	7.45189	4	0	6
174	b.b24x4	7.45227	4	14	6
175	b.b24x6	6.00092	4	14	8
176	b.l24x2	4.68435	4	8	6
177	b.l24x3	4.41049	4	0	5
178	b.l25x3	7.99141	5	11	9
179	b.l28x1	10.4623	7	1	9
180	b.l28x2	6.81027	4	11	9
181	b.b28x2	4.6253	4	0	4
182	b.b28x3	3.81055	5	3	7
183	b.b28x4	7.22064	4	11	6
184	b.b28x6	8.25873	5	11	9
185	g.h1x12	1.72902	4	0	6
186	b.1x1	1.21256	5	0	0
187	NT	3.56642	8	2	0
188	H.HA.19	0.0129365	4	15	6
189	H.HC.03	0.00632381	5	15	3
190	H.HC.07	0.0104127	4	15	6
191	H.HD.07	0.0145556	4	0	5
192	H.hdhe.01	0.0116138	6	0	6
193	H.HE.05	0.0111048	5	0	7
194	H.HE.06	0.013627	4	0	7
195	H.HF.06	0.018881	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.l2x3	b.l2x5	35.0739	2.89799	No	No	0	8	5
2	b.b3x1	b.l2x3	34.953	6.37813	No	No	0	5	8
3	b.b3x1	b.b6x5	34.8325	3.92033	No	Yes	0	5	6
4	b.l2x5	b.l4x2	37.0811	22.4287	No	Yes	0	5	4
5	b.l4x2	g.ctx15	36.9463	10.126	Yes	Yes	3	4	9
6	b.l27x5	g.ctx15	45.3504	5.42307	No	Yes	0	5	9
7	b.l27x5	g.ctx4	50.3151	5.77563	No	No	0	5	7
8	g.ctx3	g.ctx4	50.4261	3.77686	Yes	No	0	9	7
9	g.ctx3	g.ctx5	52.2054	2.68932	Yes	Yes	8	9	9
10	b.b27x1	g.ctx5	51.6628	2.72735	No	Yes	0	6	9
11	b.b26x5	b.b27x1	52.1055	3.84497	No	No	0	7	6
12	b.b22x4	b.b26x5	52.2055	3.28024	No	No	0	5	7
13	b.b22x4	b.b26x3	52.3081	3.24996	No	No	0	5	6
14	b.b22x2	b.b26x3	55.9536	4.39674	No	No	0	8	6
15	b.b22x1	b.b22x2	56.0554	3.34574	No	No	0	8	8
16	b.b22x1	b.l23x1	56.1576	3.49552	No	Yes	0	8	6
17	b.l23x1	b.l25x6	69.2007	18.7549	Yes	No	0	6	8
18	b.b2x1	b.l28x1	10.0667	7.72347	Yes	Yes	1	8	9
19	b.b2x1	b.l3x1	10.4362	12.8231	Yes	No	1	8	9
20	b.l3x1	b.l5x5	10.8031	5.91918	No	Yes	1	9	9
21	G.H3.17	b.l25x6	59.5035	3.84918	Yes	No	1	5	8
22	G.H3.15	G.H3.17	60.2812	4.60159	No	Yes	0	8	5
23	G.H3.15	G.H3.18	60.3701	4.34416	No	Yes	0	8	9
24	G.H3.18	G.S4.02	60.5191	7.38963	Yes	No	16	9	8
25	G.S1.05	G.S4.02	60.7318	2.69879	No	No	0	9	8
26	G.S1.05	G.S1.07	64.8461	5.97496	No	No	0	9	9
27	G.S1.07	G.S4.04	64.958	2.80587	No	Yes	0	9	9
28	G.S4.04	G.S5.04	89.7539	2.88926	Yes	Yes	6	9	9
29	G.S5.04	G.S5.06	90.1725	3.72995	Yes	No	0	9	8
30	G.S5.06	G.s4h3.01	90.5002	7.56302	No	No	0	8	7
31	G.HG.04	G.s4h3.01	90.5929	8.65347	Yes	No	0	9	7
32	G.HG.04	G.s4h3.04	91.1372	4.29363	Yes	Yes	9	9	8
33	G.HG.07	G.s4h3.04	98.8635	6.90949	No	Yes	9	9	8
34	G.HG.07	G.s4h3.02	99.5685	3.27826	No	No	0	9	9
35	G.s4h3.02	G.s5hg.01	99.6837	5.32183	No	No	0	9	9
36	G.S5.07	G.s5hg.01	100	2.71054	Yes	No	0	9	9
37	G.H1.04	G.S5.07	49.8367	4.10736	No	Yes	0	7	9
38	G.H1.04	G.S5.05	49.8166	3.30576	No	Yes	0	7	9
39	G.S5.07	G.s6h5.01	50.2379	5.85442	Yes	No	0	9	9
40	G.S5.05	G.s6h5.01	49.7691	4.82437	Yes	No	12	9	9
41	G.H2.06	b.l9x6	30.6526	3.74598	Yes	Yes	1	9	8
42	G.H2.04	G.H2.07	30.7541	3.50966	No	Yes	0	9	9
43	G.H2.04	G.H3.08	30.8027	3.40543	No	No	0	9	9
44	G.H3.08	G.S4.04	30.8841	5.35879	No	Yes	0	9	9
45	G.H2.06	b.l17x6	29.8394	7.55967	Yes	Yes	1	9	9
46	G.H3.06	G.hgh4.02	10.6405	4.53933	No	Yes	0	6	7
47	G.S5.03	G.S5.05	95.7473	3.01056	No	Yes	0	8	9
48	G.H5.10	G.S5.03	95.5985	3.29146	No	No	0	6	8
49	G.H5.10	G.S6.02	95.5239	5.44347	No	Yes	0	6	7
50	G.S6.02	G.h4s6.12	47.6442	12.24	Yes	Yes	0	7	4
51	G.H5.13	G.S6.02	47.5876	6.03686	Yes	Yes	0	8	7
52	G.H5.17	G.h4s6.12	46.6805	3.76345	No	Yes	0	5	4
53	G.H5.13	G.H5.17	46.6674	3.18496	Yes	No	0	8	5
54	G.H5.17	G.H5.26	93.1236	3.68612	No	Yes	0	5	5
55	G.H5.20	G.H5.26	91.1716	5.73568	Yes	Yes	0	9	5
56	G.H5.20	G.H5.25	90.2978	2.8984	Yes	Yes	0	9	7
57	3x50	G.H5.25	89.6211	5.77736	Yes	Yes	2	9	7
58	b.l17x5	b.l17x6	30.2263	2.98783	No	Yes	1	6	9
59	b.l17x5	b.l19x2	30.1142	3.7798	No	Yes	1	6	9
60	b.b20x4	b.b20x6	16.43	4.32738	Yes	Yes	1	8	6
61	b.b17x7	b.b20x6	22.9019	8.78632	Yes	Yes	1	8	6
62	b.b17x7	b.b21x1	21.7312	4.34074	Yes	Yes	1	8	7
63	b.l17x3	b.l19x2	20.7713	3.22953	Yes	Yes	1	9	9
64	b.b19x4	b.l17x3	11.5641	8.58922	Yes	Yes	1	8	9
65	b.1x19	b.b21x1	18.8313	8.06302	No	Yes	0	2	7
66	2x53	2x57	11.5615	3.08002	No	Yes	0	8	8
67	2x53	7x46	13.0314	3.9873	No	No	0	8	9
68	2x50	7x46	13.5222	6.69127	Yes	No	0	9	9
69	2x46	2x50	11.2255	3.95083	Yes	Yes	2	9	9
70	2x46	3x43	14.1727	3.42753	Yes	Yes	2	9	8
71	3x43	7x53	61.9438	5.49294	Yes	Yes	2	8	9
72	3x50	7x53	62.9085	5.66399	Yes	Yes	2	9	9
73	2x50	7x49	11.2118	6.30138	Yes	Yes	2	9	9
74	3x43	7x49	12.0106	3.83296	Yes	Yes	2	8	9
75	3x36	Lig	28.1763	5.76671	No	Yes	2	7	0
76	3x36	6x48	28.3971	3.93863	No	Yes	2	7	8
77	6x44	6x48	32.4952	6.80449	Yes	Yes	2	9	8
78	3x43	6x44	35.9469	3.3721	Yes	Yes	2	8	9
79	2x43	7x54	10.3703	2.51589	No	Yes	0	8	8
80	2x43	3x46	10.6259	2.48734	No	Yes	0	8	9
81	3x46	3x50	19.6418	4.89409	Yes	Yes	2	9	9
82	2x42	3x46	10.0864	2.71619	Yes	Yes	0	8	9
83	E2	Lig	15.1331	12.6401	Yes	Yes	2	5	0
84	b.b2x4	b.b6x5	27.866	2.98502	No	Yes	0	6	6
85	b.b10x4	b.b2x4	27.7282	11.5709	No	No	0	6	6
86	b.b10x2	b.b10x4	16.2028	4.06152	No	No	0	6	6
87	b.b10x2	b.b14x3	16.068	4.15616	No	Yes	0	6	5
88	b.b10x4	b.b14x5	11.4025	2.86602	No	No	0	6	5
89	b.b14x5	b.l10x1	11.2644	5.02182	No	No	0	5	3
90	b.b11x1	b.l10x1	10.9933	4.82779	No	No	0	5	3
91	b.b14x3	b.b15x1	13.8232	3.96315	Yes	Yes	4	5	9
92	b.b13x7	b.b15x1	11.0108	10.2037	Yes	Yes	4	7	9
93	b.b13x5	b.b13x7	10.7091	5.64497	No	Yes	0	4	7
94	b.b13x4	b.b13x5	21.0022	2.99718	No	No	0	4	4
95	b.b12x7	b.b13x4	20.7224	2.6645	Yes	No	0	9	4
96	b.b11x1	b.b12x5	10.7228	5.1667	No	No	0	5	6
97	b.b12x5	b.b13x5	10.5876	4.69864	No	No	0	6	4
98	b.b12x7	b.l12x3	19.8825	7.35067	Yes	No	0	9	5
99	b.b21x7	b.b24x6	11.1233	7.55943	Yes	Yes	0	5	8
100	b.b23x6	b.b24x6	11.1309	6.89932	Yes	Yes	14	7	8
101	b.l21x7	b.l23x1	13.2904	4.44105	No	Yes	0	5	6
102	b.b23x6	b.l23x2	12.5239	3.30438	Yes	No	0	7	8
103	b.l21x7	b.l23x2	13.008	7.13131	No	No	0	5	8
104	b.1x15	b.1x19	17.0804	4.30639	No	No	0	4	2
105	b.1x12	b.1x15	16.2044	1.49073	No	No	0	1	4
106	b.1x12	g.h1x11	12.6961	3.41495	No	No	0	1	9
107	b.1x11	g.h1x11	12.2571	4.79993	No	No	0	6	9
108	b.b13x2	b.l12x3	19.322	4.33056	No	No	0	4	5
109	b.1x11	g.h1x12	11.3788	2.3937	No	Yes	0	6	6
110	H.hdhe.01	b.b13x2	19.0374	0.00714286	Yes	No	0	6	4
111	H.hdhe.01	H.hdhe.03	17.4509	0.00742857	Yes	No	0	6	7
112	H.HD.07	H.hdhe.03	16.9977	0.00774603	Yes	No	0	5	7
113	G.H2.07	b.l9x6	29.6823	3.02769	Yes	Yes	1	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x56	3x32	4.03587	0	No	No	8	8	2	1
2x57	7x42	6.43859	2	Yes	Yes	8	8	2	1
E1x49	E2	3.85477	0	No	Yes	5	5	2	1
3x25	E1x50	5.08562	2	No	Yes	9	9	2	2
3x22	3x26	4.40096	2	No	No	4	7	2	2
3x32	7x42	2.7936	2	No	Yes	8	8	1	1
3x32	Lig	6.89137	2	No	Yes	8	0	1	0
3x33	4x57	2.99009	2	No	No	8	8	1	2
3x33	Lig	5.76865	2	No	Yes	8	0	1	0
3x36	6x48	3.93863	2	No	Yes	7	8	1	2
3x36	Lig	5.76671	2	No	Yes	7	0	1	0
E2	E2x51	6.45882	2	Yes	No	5	5	1	1
E2x52	Lig	8.64019	2	No	Yes	6	0	1	0
5x36	E2	5.62848	2	No	Yes	6	5	2	1
5x39	E2	4.43608	2	No	Yes	8	5	2	1
5x39	5x43	3.34632	2	No	No	8	8	2	1
5x43	Lig	4.01341	2	No	Yes	8	0	1	0
6x48	7x41	4.98117	2	Yes	No	8	8	2	2
6x51	7x37	2.8621	2	Yes	No	8	6	1	2
6x51	7x38	4.73115	2	Yes	No	8	7	1	1
6x51	Lig	5.88919	2	Yes	Yes	8	0	1	0
6x54	7x37	3.17063	0	No	No	6	6	2	2
6x55	Lig	3.87678	2	No	Yes	8	0	1	0
E3	E3	7.2189	2	Yes	Yes	4	4	2	2
7x38	7x42	4.69333	2	No	Yes	7	8	1	1
7x42	Lig	4.48438	2	Yes	Yes	8	0	1	0
E2	E2	47.0989	2	Yes	Yes	5	5	1	1
6x51	6x55	3.88914	2	Yes	No	8	8	1	1
4x64	E2	5.35384	0	No	Yes	0	5	2	1
6x54	7x34	3.49692	0	No	Yes	6	4	2	1
E2	Lig	12.6401	2	Yes	Yes	5	0	1	0
7x38	Lig	5.76209	2	No	Yes	7	0	1	0
E1x50	E2	3.12304	2	Yes	Yes	9	5	2	1
3x22	E2	7.76196	2	No	Yes	4	5	2	1
E2	E2x52	5.7259	2	Yes	No	5	6	1	1
6x55	7x34	2.78406	2	No	Yes	8	4	1	1
3x26	E2	4.24768	2	No	Yes	7	5	2	1
7x34	E2	5.27871	2	Yes	Yes	4	5	1	1
2x60	Lig	4.55368	0	No	Yes	7	0	1	0
1x39	2x57	4.09302	2	Yes	Yes	7	8	2	2
1x39	7x42	3.89343	2	Yes	Yes	7	8	2	1
3x25	E2	3.53266	2	No	Yes	9	5	2	1
E2x51	Lig	4.40833	2	No	Yes	5	0	1	0
7x34	Lig	2.99052	2	Yes	Yes	4	0	1	0
6x51	7x41	2.87153	2	Yes	No	8	8	1	2
NT	NT	7.68672	2	Yes	Yes	0	0	1	1
E2	NT	5.20348	2	Yes	Yes	5	0	1	1
Lig	NT	4.48119	2	Yes	Yes	0	0	0	1
5x40	E2	2.62143	2	No	Yes	7	5	2	1
4x65	E2x52	2.33715	0	No	No	0	6	2	1
E2	E3	2.23905	2	Yes	Yes	5	4	1	2
7x31	E2	1.96847	2	No	Yes	2	5	2	1
5x35	E2	1.89758	2	No	Yes	0	5	2	1
7x24	NT	1.67397	0	No	Yes	0	0	2	1
4x63	E2	1.55436	2	No	Yes	5	5	2	1
5x34	NT	1.37413	0	No	Yes	0	0	2	1
5x32	E2	1.26258	0	No	Yes	0	5	2	1
7x27	Lig	1.24679	0	No	Yes	0	0	1	0
1x27	E2	0.97746	2	No	Yes	0	5	2	1
5x31	E2	0.896573	0	No	Yes	0	5	2	1
1x25	E2	0.824286	0	No	Yes	0	5	2	1
E1x501	NT	0.365976	0	No	Yes	0	0	2	1
5x29	E2	0.323956	2	No	Yes	0	5	2	1
4x68	E2	0.0859048	2	No	Yes	0	5	2	1
5x28	E2	0.0779243	2	No	Yes	0	5	2	1
E1x48	NT	0.0591429	0	No	Yes	0	0	2	1
5x27	E2	0.0427106	2	No	Yes	0	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
70.00	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
68.75	Single	5C1M	BU72	5C1M-μ-BU72
68.42	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
68.42	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
66.67	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
66.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
64.71	Single	8E0G	BU72	8E0G-μ-BU72
64.71	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
63.16	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
62.50	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
62.50	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
62.50	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
62.50	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
61.11	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
61.11	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
60.00	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
60.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
60.00	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
60.00	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
60.00	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
60.00	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
60.00	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
60.00	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
60.00	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
60.00	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
58.82	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
58.82	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
58.82	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
58.82	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
58.82	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
58.82	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
58.82	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
58.82	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
57.14	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
56.52	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
56.25	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
56.25	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
56.25	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
56.25	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
56.25	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
56.25	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
56.25	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
56.00	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
56.00	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
56.00	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
55.56	Single	2YDV	NECA	2YDV-A_2A-NECA
55.56	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
55.56	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
55.56	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
55.56	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
55.56	Single	5G53	NECA	5G53-A_2A-NECA-Gs
55.56	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
55.56	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
55.56	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
55.56	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
55.56	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
55.56	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
55.00	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
55.00	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
55.00	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
55.00	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
54.55	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
54.55	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
54.17	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
53.33	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
53.33	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
53.33	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
53.33	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
52.94	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
52.94	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
52.94	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
52.94	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
52.94	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
52.94	Single	6PS1	Timolol	6PS1-β₂-Timolol
52.94	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
52.94	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
52.94	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
52.94	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
52.94	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
52.94	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
52.94	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
52.94	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
52.94	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
52.94	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
52.94	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
52.94	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
52.94	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
52.94	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
52.94	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
52.94	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
52.94	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
52.94	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
52.94	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
52.94	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
52.94	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
52.94	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
52.94	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
52.94	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
52.63	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
52.63	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
52.63	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
52.63	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
52.63	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
52.63	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
52.63	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
52.63	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
52.63	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
52.63	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
52.63	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
52.63	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
52.63	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
52.63	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
52.63	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
52.63	Consensus	dp_off	Orthosteric Ligand	dp2_off
52.63	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
52.63	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
52.63	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
52.38	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
52.38	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
52.38	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
52.17	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
52.17	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
52.17	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
52.17	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
50.00	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
50.00	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
50.00	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
50.00	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
50.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
50.00	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
50.00	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
50.00	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
50.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
50.00	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
50.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
50.00	Single	6AKX	A4R	6AKX-CCR5-A4R
50.00	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
50.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
50.00	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
50.00	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
50.00	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
50.00	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
50.00	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
50.00	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
50.00	Single	7EZC	UKA	7EZC-A_2A-UKA
50.00	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
50.00	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
50.00	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
50.00	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
50.00	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
50.00	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
50.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
50.00	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
50.00	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
50.00	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
50.00	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
50.00	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
50.00	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
50.00	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
50.00	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
50.00	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
50.00	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
50.00	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
50.00	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
50.00	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
50.00	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
50.00	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
50.00	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
50.00	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
50.00	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
50.00	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
50.00	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
50.00	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
50.00	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
50.00	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
50.00	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
50.00	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
50.00	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
50.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
50.00	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
48.15	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
48.15	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
48.00	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
48.00	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
47.83	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
47.83	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
47.83	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
47.62	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
47.62	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.62	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
47.62	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
47.62	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.62	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
47.62	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
47.62	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
47.62	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
47.62	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
47.37	Single	3P0G	BI167107	3P0G-β₂-BI167107
47.37	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
47.37	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
47.37	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
47.37	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
47.37	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
47.37	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
47.37	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
47.37	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
47.37	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
47.37	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
47.37	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
47.37	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
47.37	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
47.37	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
47.37	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
47.37	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
47.37	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
47.37	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
47.37	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
47.37	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
47.37	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
47.37	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
47.37	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
47.37	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
47.37	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.37	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
47.37	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
47.37	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
47.37	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
47.37	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.37	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
47.37	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
47.06	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
47.06	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
47.06	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
47.06	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
47.06	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
47.06	Single	6TPG	EMPA	6TPG-OX₂-EMPA
47.06	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
47.06	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
47.06	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
47.06	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
47.06	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
47.06	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
47.06	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
47.06	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
47.06	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
47.06	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
47.06	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
47.06	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
47.06	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
47.06	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
47.06	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
47.06	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.06	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
47.06	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
47.06	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
47.06	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
47.06	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
47.06	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
47.06	Consensus	hcar_on	Orthosteric Ligand	hca_on
47.06	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
47.06	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
46.67	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
46.67	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
45.83	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
45.83	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
45.83	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
45.83	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
45.83	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
45.45	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
45.45	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
45.45	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
45.45	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
45.00	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
45.00	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
45.00	Single	4LDE	BI167107	4LDE-β₂-BI167107
45.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
45.00	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
45.00	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
45.00	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
45.00	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
45.00	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
45.00	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
45.00	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
45.00	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
45.00	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
45.00	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
45.00	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
45.00	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
45.00	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
45.00	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
45.00	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
44.83	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
44.44	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
44.44	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
44.44	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
44.44	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
44.44	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
44.44	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
44.44	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
44.44	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
44.44	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
44.44	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
44.44	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
44.44	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
44.44	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
44.44	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
44.44	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
44.44	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
44.44	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
44.44	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
44.44	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
44.44	Single	7BU7	BI167107	7BU7-β₁-BI167107
44.44	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
44.44	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
44.44	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
44.44	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
44.44	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
44.44	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
44.44	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
44.44	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
44.44	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
44.44	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
44.44	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
44.44	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
44.44	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
44.44	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
44.44	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
44.44	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
44.44	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
44.44	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
44.44	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
44.44	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
44.44	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
44.44	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
44.44	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
44.44	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
44.44	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
44.44	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
44.44	Consensus	tar_on	Orthosteric Ligand	ta1_on
44.00	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
44.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
44.00	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.00	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
44.00	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.00	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.00	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.75	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
43.75	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
43.75	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
43.75	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
43.75	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
43.75	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
43.75	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
43.75	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
43.75	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
43.75	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
43.75	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
43.75	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
43.75	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
43.75	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
43.75	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
43.48	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
43.48	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
43.48	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
43.48	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
43.48	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
43.33	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
43.33	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
43.33	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
42.86	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
42.86	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
42.86	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
42.86	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
42.86	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
42.86	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
42.86	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
42.86	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
42.86	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
42.86	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
42.86	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
42.86	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
42.86	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
42.86	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
42.86	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
42.86	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
42.86	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
42.86	Consensus	endothelin_off	Orthosteric Ligand	etb_off
42.86	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
42.86	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
42.86	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
42.31	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
42.31	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
42.11	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
42.11	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
42.11	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
42.11	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
42.11	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
42.11	Single	5WQC	EMPA	5WQC-OX₂-EMPA
42.11	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
42.11	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
42.11	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
42.11	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
42.11	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
42.11	Single	6PS6	Timolol	6PS6-β₂-Timolol
42.11	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
42.11	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
42.11	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
42.11	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
42.11	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
42.11	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
42.11	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
42.11	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
42.11	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
42.11	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
42.11	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
42.11	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
42.11	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
42.11	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
42.11	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
42.11	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
42.11	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
42.11	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
42.11	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
42.11	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
42.11	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
42.11	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
42.11	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
41.67	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
41.67	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
41.67	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
41.67	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
41.67	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
41.18	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
41.18	Single	5WS3	EMPA	5WS3-OX₂-EMPA
41.18	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
41.18	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
41.18	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
41.18	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
41.18	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
41.18	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
41.18	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
41.18	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
41.18	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
41.18	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
41.18	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
41.18	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
41.18	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
41.18	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
41.18	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
41.18	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
41.18	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
41.18	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
41.18	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
41.18	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
41.18	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
41.18	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
41.18	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
41.18	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
41.18	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
41.18	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
41.18	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
41.18	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
41.18	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
41.18	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
41.18	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
41.18	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
41.18	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
41.18	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
40.91	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
40.91	Single	6PT3	DPI-287	6PT3-δ-DPI-287
40.91	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
40.91	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.91	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
40.91	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
40.91	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
40.91	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
40.91	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
40.91	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
40.91	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
40.91	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
40.91	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
40.91	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
40.74	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.74	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
40.74	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
40.74	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
40.74	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
40.00	Single	4DJH	JDTic	4DJH-κ-JDTic
40.00	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
40.00	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
40.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
40.00	Single	5X93	K-8794	5X93-ET_B-K-8794
40.00	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
40.00	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
40.00	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
40.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
40.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
40.00	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
40.00	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
40.00	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
40.00	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
40.00	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
40.00	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
40.00	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
40.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
40.00	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
40.00	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
40.00	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
40.00	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
40.00	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
40.00	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
40.00	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
40.00	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
40.00	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
40.00	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
40.00	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
40.00	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
40.00	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
40.00	Consensus	histamine_off	Orthosteric Ligand	h1_off
40.00	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
40.00	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
40.00	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
40.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
40.00	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
39.29	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
39.29	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
39.29	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
39.29	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
39.13	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
39.13	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
39.13	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
39.13	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
39.13	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
39.13	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
39.13	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
39.13	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
39.13	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
39.13	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
39.13	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
39.13	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
39.13	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
38.89	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
38.89	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
38.89	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
38.89	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
38.89	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
38.89	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
38.89	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
38.89	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
38.89	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
38.89	Single	6VI4	JDTic	6VI4-κ-JDTic
38.89	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
38.89	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
38.89	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
38.89	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
38.89	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
38.89	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
38.89	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
38.89	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
38.89	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
38.89	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
38.89	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
38.89	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
38.89	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
38.89	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
38.89	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
38.89	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
38.89	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
38.89	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
38.89	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
38.89	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
38.89	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
38.89	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
38.89	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
38.89	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
38.89	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
38.89	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
38.89	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
38.71	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
38.46	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
38.46	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
38.46	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
38.46	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
38.10	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
38.10	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
38.10	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
38.10	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
38.10	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
38.10	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
38.10	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
38.10	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
38.10	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
38.10	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.10	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
38.10	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
38.10	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
38.10	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
38.10	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
38.10	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
38.10	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
38.10	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
38.10	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
38.10	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
38.10	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
38.10	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
38.10	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
38.10	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
38.10	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
38.10	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
38.10	Consensus	gi_class-f	Other Ligand	gi_frizzled
38.10	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
38.10	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
38.10	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
38.10	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
38.10	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
38.10	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
37.50	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
37.50	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
37.50	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
37.50	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
37.50	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
37.50	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
37.50	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
37.50	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
37.50	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
37.50	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
37.50	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
37.50	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
37.50	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
37.50	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
37.50	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
37.50	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
37.50	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
37.04	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
37.04	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
37.04	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.04	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.04	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.04	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
37.04	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
37.04	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
37.04	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
36.84	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
36.84	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
36.84	Single	5UEN	DU172	5UEN-A₁-DU172
36.84	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
36.84	Single	6D27	CAY10471	6D27-DP₂-CAY10471
36.84	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
36.84	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
36.84	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
36.84	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
36.84	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
36.84	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
36.84	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
36.84	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
36.84	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
36.84	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
36.84	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
36.84	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
36.84	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
36.84	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
36.84	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
36.84	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
36.84	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
36.84	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
36.84	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
36.84	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
36.84	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
36.84	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
36.84	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
36.84	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
36.67	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
36.36	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
36.36	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
36.36	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
36.36	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
36.36	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
36.36	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
36.36	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
36.36	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
36.36	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
36.36	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
36.36	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
36.00	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
36.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
36.00	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
36.00	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
36.00	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
36.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
36.00	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
36.00	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
36.00	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
36.00	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
36.00	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
36.00	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
36.00	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.71	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
35.71	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
35.71	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
35.71	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
35.48	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
35.29	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
35.29	Single	6HLL	CP99994	6HLL-NK₁-CP99994
35.29	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
35.29	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
35.29	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
35.29	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
35.29	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
35.29	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
35.29	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
35.29	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
35.29	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
35.00	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
35.00	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
35.00	Single	5N2S	PSB36	5N2S-A₁-PSB36
35.00	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
35.00	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
35.00	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
35.00	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
35.00	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
35.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
35.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
35.00	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
35.00	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
35.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
35.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
35.00	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
35.00	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
35.00	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
35.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
35.00	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
35.00	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
35.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.00	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
35.00	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
34.78	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
34.78	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
34.78	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
34.78	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
34.78	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
34.78	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
34.78	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
34.78	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
34.78	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.78	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
34.78	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
34.78	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
34.78	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.62	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
34.62	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
34.62	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
34.62	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
34.62	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
34.62	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
34.62	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
34.62	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.48	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
34.48	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
33.33	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
33.33	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
33.33	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
33.33	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
33.33	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
33.33	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
33.33	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
33.33	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
33.33	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
33.33	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
33.33	Single	5XR8	AM841	5XR8-CB₁-AM841
33.33	Single	5XRA	AM11542	5XRA-CB₁-AM11542
33.33	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
33.33	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
33.33	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
33.33	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
33.33	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
33.33	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
33.33	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
33.33	Single	6OS1	TRV026	6OS1-AT₁-TRV026
33.33	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
33.33	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
33.33	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
33.33	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
33.33	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
33.33	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
33.33	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
33.33	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
33.33	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
33.33	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
33.33	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
33.33	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
33.33	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
33.33	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
33.33	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
33.33	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
33.33	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
33.33	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
33.33	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
33.33	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
33.33	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
33.33	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
33.33	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
33.33	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
33.33	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
33.33	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
33.33	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
33.33	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
33.33	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
33.33	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
33.33	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
33.33	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
33.33	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
33.33	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
33.33	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
33.33	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
33.33	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
33.33	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
33.33	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
33.33	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
33.33	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
33.33	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
33.33	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
33.33	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
33.33	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
33.33	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
33.33	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
33.33	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
33.33	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
33.33	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
33.33	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
33.33	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
33.33	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
33.33	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
33.33	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
33.33	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
33.33	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
33.33	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
33.33	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
33.33	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
33.33	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
33.33	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
33.33	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
33.33	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
33.33	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
33.33	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
33.33	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
33.33	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
32.26	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
32.26	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
32.26	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
32.14	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
32.14	Single	6FJ3	PTH	6FJ3-PTH1-PTH
32.14	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
32.14	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
32.14	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
32.00	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
32.00	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
32.00	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
32.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
32.00	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
31.82	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
31.82	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
31.82	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
31.82	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
31.82	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
31.82	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
31.82	Single	6OS2	TRV026	6OS2-AT₁-TRV026
31.82	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
31.82	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
31.82	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
31.82	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
31.82	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
31.82	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.82	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.82	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
31.82	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
31.82	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
31.82	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
31.82	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
31.82	Consensus	blt_off	Orthosteric Ligand	blt1_off
31.82	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
31.82	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
31.82	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
31.82	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
31.82	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
31.58	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
31.58	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
31.58	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
31.58	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
31.58	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
31.58	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
31.58	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
31.58	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
31.58	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
31.58	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
31.58	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
31.58	Single	6IQL	L745870	6IQL-D₄-L745870
31.58	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
31.58	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
31.58	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
31.58	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
31.58	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
31.58	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
31.58	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
31.58	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
31.58	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
31.58	Single	7T32	ZM241385	7T32-A_2A-ZM241385
31.58	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
31.58	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
31.58	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
31.58	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.58	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.58	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
31.58	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
31.58	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
31.58	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
31.58	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.58	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
31.58	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
31.58	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
31.58	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
31.58	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
31.58	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
31.58	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
31.58	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
31.25	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
31.25	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
31.25	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
31.25	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
31.25	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
31.25	Consensus	sensory_on	Orthosteric Ligand	opsin_on
31.03	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
31.03	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
31.03	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
31.03	Consensus	go_class-b1	Orthosteric Ligand	go_crf
31.03	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
30.77	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
30.77	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
30.43	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
30.43	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
30.43	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
30.43	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
30.43	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
30.43	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
30.43	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
30.43	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
30.43	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
30.43	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
30.30	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
30.00	Single	3EML	ZM241385	3EML-A_2A-ZM241385
30.00	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
30.00	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
30.00	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
30.00	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
30.00	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
30.00	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
30.00	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
30.00	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
30.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
30.00	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
30.00	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
30.00	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
30.00	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
30.00	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
30.00	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
30.00	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
30.00	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
30.00	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
30.00	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
30.00	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
30.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
30.00	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
30.00	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
30.00	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
30.00	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
30.00	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
30.00	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
30.00	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
30.00	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
30.00	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
30.00	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
30.00	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
30.00	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
30.00	Consensus	a2_off	Orthosteric Ligand	a2a_off
30.00	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
30.00	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
30.00	Consensus	blt_on	Orthosteric Ligand	blt1_on
30.00	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
30.00	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
30.00	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.00	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
30.00	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
30.00	Consensus	leuko_on	Orthosteric Ligand	blt_on
30.00	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
30.00	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
30.00	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
30.00	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
29.63	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
29.63	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
29.63	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
29.63	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
29.41	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
29.41	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
29.41	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
29.41	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
29.41	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
29.41	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
29.41	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
29.41	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
29.41	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
29.41	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
29.41	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
29.41	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
29.41	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
29.41	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
29.41	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
29.17	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
29.17	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.17	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
29.17	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
29.17	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
29.17	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
29.17	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
29.17	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.03	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
29.03	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
28.57	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
28.57	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
28.57	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
28.57	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
28.57	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
28.57	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
28.57	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
28.57	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
28.57	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
28.57	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
28.57	Single	7C4S	S1P	7C4S-S1P₃-S1P
28.57	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
28.57	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
28.57	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
28.57	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
28.57	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
28.57	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
28.57	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
28.57	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
28.57	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
28.57	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
28.57	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
28.57	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
28.57	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
28.57	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
28.57	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
28.57	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
28.57	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
28.57	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
28.57	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
28.57	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
28.57	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
28.57	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.12	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
28.12	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
28.12	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
28.12	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
28.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
28.00	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
28.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
28.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
28.00	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
28.00	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
28.00	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
28.00	Consensus	class-d_off	Orthosteric Ligand	ste2_off
28.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
28.00	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.78	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
27.78	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
27.78	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
27.78	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
27.78	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
27.78	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
27.78	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
27.78	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
27.78	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
27.78	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
27.78	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
27.78	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
27.78	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.78	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.78	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
27.78	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.78	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
27.78	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
27.78	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
27.78	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
27.78	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
27.78	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
27.78	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
27.78	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
27.78	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
27.78	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
27.59	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
27.59	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
27.59	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
27.59	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
27.59	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
27.59	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
27.27	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
27.27	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
27.27	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
27.27	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
27.27	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
27.27	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
27.27	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
27.27	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
27.27	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
27.27	Single	7W41	PD176252	7W41-BB₂-PD176252
27.27	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
27.27	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
27.27	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
27.27	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
27.27	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
27.27	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
27.27	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.27	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
27.27	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
27.27	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
27.27	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
27.27	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
27.27	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
27.27	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
26.92	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
26.92	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
26.92	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
26.92	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
26.92	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
26.92	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
26.92	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.67	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
26.67	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
26.67	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
26.67	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
26.67	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
26.47	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
26.47	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
26.47	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
26.47	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
26.32	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
26.32	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
26.32	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
26.32	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
26.32	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
26.32	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
26.32	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
26.32	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
26.32	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
26.32	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
26.32	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
26.32	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
26.32	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
26.32	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
26.32	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
26.32	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.32	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
26.32	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
26.32	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
26.32	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
26.09	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
26.09	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
26.09	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
26.09	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
26.09	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
26.09	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
26.09	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
26.09	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
26.09	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
26.09	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
26.09	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
26.09	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
26.09	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
26.09	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
26.09	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
26.09	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
26.09	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
26.09	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
26.09	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
25.93	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
25.93	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
25.93	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
25.93	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.93	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.93	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
25.81	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
25.81	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
25.81	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
25.81	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
25.81	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
25.81	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
25.81	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
25.71	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
25.64	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
25.00	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
25.00	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
25.00	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
25.00	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
25.00	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
25.00	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
25.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
25.00	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
25.00	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
25.00	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
25.00	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
25.00	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
25.00	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
25.00	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
25.00	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
25.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
25.00	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
25.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
25.00	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
25.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
25.00	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
25.00	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
25.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
25.00	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
25.00	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
25.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
25.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
25.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
25.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
25.00	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
25.00	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
25.00	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
25.00	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
25.00	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
25.00	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
25.00	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
25.00	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
25.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
25.00	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
25.00	Consensus	sensory_off	Orthosteric Ligand	opsin_off
24.24	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
24.14	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
24.14	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
24.14	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
24.14	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
24.14	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
24.14	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
24.14	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
24.00	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
24.00	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
24.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
24.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
24.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
24.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Consensus	class-d_off	Orthosteric Ligand	ste2_off
24.00	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
23.81	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
23.81	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
23.81	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
23.81	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
23.81	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
23.81	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
23.81	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
23.81	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
23.81	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
23.81	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
23.81	Single	6GPS	MK0812	6GPS-CCR2-MK0812
23.81	Single	6IIV	Daltroban	6IIV-TP-Daltroban
23.81	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.81	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
23.81	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
23.81	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
23.81	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
23.81	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
23.81	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
23.81	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
23.81	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
23.81	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
23.81	Consensus	cck_off	Orthosteric Ligand	ccka_off
23.81	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
23.81	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
23.81	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
23.81	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
23.81	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
23.81	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
23.68	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
23.53	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
23.53	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
23.53	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
23.53	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
23.33	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
23.33	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
23.33	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
23.33	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
23.33	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
23.33	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
23.08	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
23.08	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
22.86	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
22.73	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
22.73	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
22.73	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
22.73	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
22.73	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
22.73	Single	6GPX	MK0812	6GPX-CCR2-MK0812
22.73	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
22.73	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
22.73	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
22.73	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
22.73	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
22.73	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
22.73	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
22.73	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
22.73	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
22.73	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
22.73	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
22.73	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
22.73	Consensus	ep_off	Orthosteric Ligand	ep4_off
22.58	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
22.58	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
22.58	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
22.58	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
22.50	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
22.22	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
22.22	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
22.22	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
22.22	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
22.22	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
22.22	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
22.22	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
22.22	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
22.22	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
21.88	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
21.88	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
21.88	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
21.88	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
21.88	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
21.74	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
21.74	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
21.74	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
21.74	Single	5V56	TC114	5V56-SMO-TC114
21.74	Single	6E59	L-760735	6E59-NK₁-L-760735
21.74	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
21.74	Single	7EPE	NAM563	7EPE-mGlu-NAM563
21.74	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
21.74	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
21.74	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
21.74	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
21.74	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.74	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.74	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
21.74	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
21.74	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
21.43	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
21.43	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
21.21	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
21.21	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
21.21	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
21.21	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
21.21	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
21.05	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
21.05	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
21.05	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
21.05	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
21.05	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
21.05	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
21.05	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
21.05	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
21.05	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
21.05	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
21.05	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
21.05	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
20.83	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
20.83	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
20.83	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
20.83	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
20.83	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
20.83	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
20.83	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.83	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
20.83	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
20.83	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
20.83	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
20.83	Consensus	nts_on	Orthosteric Ligand	nts1_on
20.83	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
20.69	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
20.69	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
20.69	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
20.59	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
20.00	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
20.00	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
20.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
20.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
20.00	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
20.00	Single	5U09	Taranabant	5U09-CB₁-Taranabant
20.00	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
20.00	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
20.00	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
20.00	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
20.00	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
20.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
20.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
20.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
20.00	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
20.00	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
20.00	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
20.00	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
20.00	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
20.00	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
20.00	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
20.00	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
20.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
20.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
20.00	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
20.00	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
20.00	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
19.35	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
19.35	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
19.35	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
19.35	Consensus	class-d_on	Orthosteric Ligand	ste2_on
19.23	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
19.23	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.23	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.23	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
19.23	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
19.23	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
19.05	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
19.05	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
19.05	Single	6TPK	Retosiban	6TPK-OT-Retosiban
19.05	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
19.05	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
19.05	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
19.05	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
19.05	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
19.05	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
19.05	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
19.05	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
19.05	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
18.92	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
18.75	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
18.75	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
18.75	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
18.75	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
18.75	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
18.75	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
18.75	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
18.75	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
18.75	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
18.18	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
18.18	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
18.18	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
18.18	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
18.18	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
18.18	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
18.18	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
18.18	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
18.18	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
18.18	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
18.18	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
18.18	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
18.18	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
18.18	Consensus	hcar_off	Orthosteric Ligand	succinate_off
18.18	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
18.18	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
17.86	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
17.86	Consensus	sst_off	Orthosteric Ligand	sst2_off
17.65	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
17.65	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
17.65	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
17.50	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
17.39	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
17.39	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
17.39	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
17.39	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
17.39	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
17.39	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
17.24	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
17.24	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
17.07	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
16.67	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
16.67	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
16.67	Single	5V57	TC114	5V57-SMO-TC114
16.67	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
16.67	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
16.67	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
16.67	Single	7P2L	4YI	7P2L-mGlu₅-4YI
16.67	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
16.67	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
16.67	Consensus	class-d_on	Orthosteric Ligand	ste2_on
16.67	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
16.67	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
16.67	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
16.67	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
16.67	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
16.22	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
16.00	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
16.00	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
16.00	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
16.00	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
16.00	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
16.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.00	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.00	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
16.00	Consensus	nts_off	Orthosteric Ligand	nts1_off
15.79	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
15.79	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
15.79	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
15.79	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
15.62	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
15.62	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
15.38	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
15.38	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
15.38	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
15.38	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
15.38	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
15.15	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
15.15	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
15.15	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
15.00	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
15.00	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
15.00	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
15.00	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
15.00	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
15.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
15.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
15.00	Consensus	class-t_on	Orthosteric Ligand	taste2_on
15.00	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
15.00	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
15.00	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
15.00	Consensus	go_protein	Orthosteric Ligand	go_chemokine
15.00	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
15.00	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
15.00	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
15.00	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
14.81	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
14.29	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
14.29	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
14.29	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
14.29	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
14.29	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
14.29	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
14.29	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
14.29	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
14.29	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
14.29	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
14.29	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
14.29	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
14.29	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
14.29	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
14.29	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
14.29	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
13.79	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
13.79	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
13.64	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
13.64	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
13.64	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
13.64	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
13.64	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
13.64	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.64	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
13.64	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
13.64	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.64	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
13.64	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
13.04	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
13.04	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
13.04	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
13.04	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
13.04	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
13.04	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.90	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
12.50	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
12.50	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
12.50	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
12.50	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
12.00	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
12.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
12.00	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
12.00	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
12.00	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
11.54	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
11.54	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
11.54	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
11.54	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
11.43	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
11.11	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
11.11	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
11.11	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
11.11	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
10.53	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
10.53	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
10.53	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
10.53	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
10.00	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
10.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
10.00	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
10.00	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
10.00	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
9.52	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
9.52	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.52	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
9.52	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
9.52	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
9.09	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
9.09	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
9.09	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.09	Consensus	class-f_off	Orthosteric Ligand	smo_off
8.70	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
8.70	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
8.70	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
8.70	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
8.70	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
8.33	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
8.33	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
8.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
7.41	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.41	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
6.67	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
6.67	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
6.67	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
6.67	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
6.67	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
6.67	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
6.67	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
6.67	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
6.67	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
6.67	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
6.67	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
6.67	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
6.67	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
6.67	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
6.67	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
6.67	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
6.67	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
6.67	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
6.67	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
6.67	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
6.67	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
6.67	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
6.67	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
6.67	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
6.67	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
6.67	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Single	7FII	hCG	7FII-LH-hCG-6fuf
6.67	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
6.67	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
6.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
6.67	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
6.67	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
6.67	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
6.67	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
6.67	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
6.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
6.67	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
6.67	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
6.67	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
6.67	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
6.67	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
6.67	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
6.67	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
6.67	Single	7XW7	K1-70	7XW7-TSH-K1-70
6.67	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
6.67	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
6.67	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
6.67	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
6.67	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
6.67	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
6.67	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
6.67	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
6.67	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
6.67	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
6.67	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
6.67	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
6.67	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
6.67	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
6.67	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
6.67	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
6.67	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
6.67	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
6.67	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
6.67	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
6.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
6.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
6.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
6.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
6.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
6.67	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
6.67	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
6.67	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
6.67	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
6.67	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
6.67	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
6.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
6.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
6.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.67	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.67	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
6.67	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
6.67	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
6.67	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
6.67	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
6.67	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
6.67	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
6.67	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
6.67	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
6.67	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
6.67	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
6.67	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
6.67	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
6.67	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
6.67	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
6.67	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
6.67	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
6.67	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
6.67	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
6.67	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
6.67	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
6.67	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
6.67	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
6.67	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
6.67	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
6.67	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
6.67	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
6.67	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
6.67	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
6.45	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
6.25	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.25	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.88	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
5.88	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
5.88	Single	8HS2	Fab046	8HS2-GPR20-Fab046
5.56	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.56	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
5.56	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.56	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
5.56	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
5.56	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
5.56	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
5.56	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
5.41	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
5.26	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
5.26	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
5.26	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
5.26	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
5.26	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
5.26	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
5.13	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
5.00	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
5.00	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
5.00	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
4.88	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
4.88	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
4.76	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
4.76	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
4.76	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
4.76	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.65	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
4.55	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
4.44	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
4.35	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
4.17	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
4.17	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.17	Single	8IYX	YL-365	8IYX-GPR34-YL-365
3.57	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
3.45	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
3.12	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.56	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
2.56	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2

Consensus Members
	Id	Members
	gi_amine	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
	gi_lipid	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
	gi_melatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
	gi_peptide	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
	gi_protein	gi_chemokine gi_chemerin
	gi_nucleotide	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
	gi_hcar	gi_hca

Net Summary
I_min	2.65405
Number of Linked Nodes	1113
Number of Links	1303
Number of Hubs	195
Number of Links mediated by Hubs	772
Number of Communities	22
Number of Nodes involved in Communities	240
Number of Links involved in Communities	351

Path Summary
Number Of Nodes in MetaPath	114
Number Of Links MetaPath	113
Number of Shortest Paths	2714470
Length Of Smallest Path	3
Average Path Length	40.6534
Length of Longest Path	84
Minimum Path Strength	0.251461
Average Path Strength	4.96682
Maximum Path Strength	21.7374
Minimum Path Correlation	0.700764
Average Path Correlation	0.964229
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.28205
Average % Of Corr. Nodes	26.9886
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	50.2948
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

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