psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.1x3	b.ntx2	5.13781	No	No	0	1	5
2	b.1x2	b.1x5	4.69156	No	No	0	1	3
3	b.1x11	g.h1x11	3.12219	No	No	0	8	9
4	b.1x13	b.1x16	4.63469	No	No	0	1	4
5	b.1x19	b.b21x2	3.25063	No	No	0	6	6
6	b.b21x2	b.lh12x1	3.08	No	No	0	6	3
7	b.lh12x2	g.h2x2	6.89969	No	No	0	8	9
8	b.h2x3	b.lh12x3	4.1225	No	No	0	1	4
9	b.h2x2	b.lh12x4	4.85	No	No	0	1	3
10	b.h2x3	b.lh12x4	5.62625	No	No	0	1	3
11	b.b21x4	b.h2x1	4.24156	No	No	0	5	5
12	b.b21x5	b.h2x1	6.36	No	No	0	4	5
13	b.h2x5	b.l24x2	4.8375	No	Yes	0	5	6
14	b.lhb1x1	b.lhb1x2	5.10656	No	No	0	1	1
15	b.l22x5	b.lhb1x6	6.17125	Yes	Yes	8	9	3
16	b.b24x7	b.lhb1x6	6.15938	Yes	Yes	8	9	3
17	b.lhb1x6	g.ctx6	3.16625	Yes	No	8	3	6
18	b.b25x7	b.lhb1x11	4.99031	No	No	0	7	4
19	b.b1x1	b.b1x3	4.29656	No	Yes	0	5	7
20	b.b1x2	b.b28x4	8.54062	No	Yes	11	3	6
21	b.b1x2	b.b28x6	9.28687	No	Yes	11	3	9
22	b.b1x3	b.b28x7	6.89344	Yes	No	3	7	9
23	b.b1x3	g.ctx16	4.00969	Yes	Yes	3	7	8
24	b.b1x4	b.b5x1	3.99969	No	No	0	7	5
25	b.b1x4	b.b28x5	3.7575	No	No	3	7	5
26	b.b1x4	g.ctx16	7.27969	No	Yes	3	7	8
27	b.b1x5	b.l1x1	7.07656	No	No	0	3	7
28	b.b1x5	b.b28x4	7.50906	No	Yes	0	3	6
29	b.b1x6	b.b4x6	20.6078	Yes	Yes	3	9	9
30	b.b1x6	b.b5x1	3.17719	Yes	No	0	9	5
31	b.b1x6	b.b28x3	6.87687	Yes	Yes	3	9	7
32	b.b1x6	b.b28x5	4.05719	Yes	No	3	9	5
33	b.b28x2	b.l1x1	7.34938	No	No	0	4	7
34	b.l1x3	b.l1x7	9.40531	Yes	No	0	9	9
35	b.b3x4	b.l1x3	6.18937	No	Yes	3	9	9
36	b.b3x6	b.l1x3	13.9909	No	Yes	3	9	9
37	b.l1x3	b.l3x2	3.38625	Yes	Yes	3	9	9
38	b.b4x4	b.l1x3	12.6781	No	Yes	3	8	9
39	b.l1x4	b.l3x2	7.25094	No	Yes	0	6	9
40	G.HN.51	b.l1x4	3.2775	No	No	0	5	6
41	b.b2x1	b.l1x6	4.73844	Yes	No	2	8	9
42	b.l1x6	b.l28x1	23.7175	No	Yes	2	9	9
43	G.h2s4.02	b.l1x6	3.375	Yes	No	2	7	9
44	b.b28x3	b.l1x7	3.52094	Yes	No	0	7	9
45	b.b2x1	b.l3x1	12.365	Yes	Yes	2	8	9
46	b.b2x1	b.l28x1	7.38781	Yes	Yes	2	8	9
47	G.H2.09	b.b2x1	5.34063	Yes	Yes	2	8	8
48	G.H2.10	b.b2x1	3.99	Yes	Yes	2	7	8
49	b.b2x3	b.b2x5	3.05125	No	Yes	0	6	7
50	b.b26x2	b.b2x3	6.02469	No	No	0	7	6
51	b.b10x4	b.b2x4	15.7963	No	No	0	6	6
52	b.b2x5	b.b3x2	8.50688	Yes	No	0	7	5
53	b.b2x5	b.l4x1	5.90625	Yes	No	0	7	5
54	b.b2x5	b.l27x1	10.1597	Yes	No	0	7	7
55	b.b27x2	b.b2x5	3.89	No	Yes	0	5	7
56	b.b6x5	b.l2x1	4.79781	Yes	No	0	6	5
57	b.l2x3	b.l2x5	3.12375	No	No	0	8	5
58	b.b3x1	b.l2x3	5.97969	No	No	0	5	8
59	b.l27x1	b.l2x4	7.04437	No	No	14	7	5
60	b.l27x3	b.l2x4	8.41844	No	No	14	7	5
61	b.b4x7	b.l2x5	15.4094	No	No	0	8	5
62	b.l2x5	b.l4x2	24.0813	No	No	0	5	4
63	b.b3x2	b.b4x6	3.95156	No	Yes	0	5	9
64	b.b3x3	b.b4x3	3.21281	Yes	Yes	0	8	7
65	b.b3x3	b.b4x5	4.22188	Yes	No	0	8	7
66	b.b3x3	b.b6x3	3.68313	Yes	No	0	8	8
67	b.b3x3	b.b6x5	5.3625	Yes	Yes	13	8	6
68	b.b3x3	b.b7x2	3.05688	Yes	No	13	8	8
69	b.b3x4	b.b4x6	5.90719	No	Yes	3	9	9
70	b.b28x3	b.b3x4	6.00688	Yes	No	3	7	9
71	b.b3x5	b.b6x3	3.2725	No	No	0	9	8
72	b.b3x6	b.l3x2	9.11063	No	Yes	3	9	9
73	b.l3x1	b.l5x5	4.51813	Yes	Yes	2	9	9
74	G.H2.10	b.l3x1	4.53156	Yes	Yes	2	7	9
75	b.b4x2	b.l3x2	4.75313	No	Yes	0	8	9
76	b.b4x1	b.l5x1	3.15281	No	Yes	0	8	8
77	G.HN.47	b.b4x2	3.78938	No	No	0	6	8
78	G.HN.50	b.b4x2	6.30937	No	No	0	5	8
79	b.b4x3	b.b5x7	4.86063	Yes	Yes	0	7	7
80	b.b4x3	b.l5x1	4.45594	Yes	Yes	0	7	8
81	b.b4x3	b.b7x4	5.25719	Yes	No	0	7	8
82	b.b4x4	b.b4x6	13.1759	No	Yes	3	8	9
83	b.b4x5	b.b5x5	7.41531	No	Yes	0	7	5
84	b.b4x5	b.l8x1	4.10125	No	Yes	0	7	5
85	b.b4x6	b.b5x3	12.7238	Yes	Yes	3	9	9
86	b.b28x3	b.b4x6	3.52594	Yes	Yes	3	7	9
87	b.b4x7	b.l4x3	7.31906	No	No	0	8	6
88	b.l4x1	g.ctx16	4.00156	No	Yes	0	5	8
89	b.l4x2	g.ctx15	11.345	No	Yes	3	4	9
90	b.l4x2	g.ctx16	7.50937	No	Yes	3	4	8
91	b.b5x2	b.l4x3	9.73375	Yes	No	0	7	6
92	G.HN.37	b.b5x2	4.63906	No	Yes	0	3	7
93	G.HN.40	b.b5x2	8.67625	No	Yes	0	7	7
94	G.HN.43	b.b5x3	5.545	No	Yes	0	9	9
95	G.HN.44	b.b5x3	9.40188	No	Yes	0	6	9
96	b.b5x4	b.b5x5	5.36406	No	Yes	0	5	5
97	b.b5x5	b.l8x8	5.40594	Yes	No	0	5	4
98	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
99	b.b5x7	b.b8x4	8.00688	Yes	Yes	0	7	6
100	b.b5x7	b.l8x8	8.35219	Yes	No	0	7	4
101	b.l5x1	b.l5x6	4.00437	Yes	No	0	8	9
102	b.b8x4	b.l5x1	5.93344	Yes	Yes	0	6	8
103	b.l5x3	b.l7x3	9.52188	No	No	0	8	9
104	b.l5x4	b.l5x5	5.25281	No	Yes	0	8	9
105	b.l5x5	b.l7x2	6.30281	Yes	Yes	2	9	9
106	G.S1.03	b.l5x5	3.73375	No	Yes	0	9	9
107	G.S2.01	b.l5x5	4.80906	No	Yes	2	9	9
108	G.S2.03	b.l5x5	10.7978	No	Yes	2	9	9
109	G.S3.06	b.l5x5	6.32031	No	Yes	2	6	9
110	G.h2s4.01	b.l5x5	8.39313	Yes	Yes	2	9	9
111	b.b6x1	b.l9x6	4.34125	No	Yes	0	9	8
112	b.b10x2	b.b6x2	3.11594	No	No	0	6	8
113	b.b10x3	b.b6x2	3.96094	No	No	0	8	8
114	b.b6x5	b.l6x4	4.30188	Yes	No	0	6	5
115	b.b6x5	b.b7x2	3.03625	Yes	No	13	6	8
116	b.b6x5	b.l8x1	3.07844	Yes	Yes	13	6	5
117	b.b10x5	b.l6x1	7.19406	Yes	No	0	9	6
118	b.l6x3	b.l6x5	7.96219	No	No	0	6	4
119	b.l10x3	b.l6x3	8.14375	No	No	0	6	6
120	b.b7x1	b.l6x5	3.30875	Yes	No	0	4	4
121	b.l6x5	b.l8x2	7.69281	No	No	0	4	4
122	b.b7x1	b.b8x3	4.04594	Yes	No	0	4	6
123	b.b7x1	b.b8x5	11.1556	Yes	No	0	4	4
124	b.b7x1	b.l10x3	4.45375	Yes	No	0	4	6
125	b.b7x2	b.l8x1	4.65625	No	Yes	13	8	5
126	b.b10x5	b.b7x3	3.59531	Yes	No	0	9	9
127	b.b7x4	b.b8x4	3.9475	No	Yes	0	8	6
128	b.l7x2	b.l9x6	4.32188	Yes	Yes	2	9	8
129	G.S2.01	b.l7x2	4.63969	No	Yes	2	9	9
130	G.H2.07	b.l7x2	3.4525	Yes	Yes	2	9	9
131	b.l7x3	b.l7x5	4.6375	No	No	0	9	6
132	b.l7x4	b.l9x5	3.5525	No	No	0	9	8
133	G.s3h2.03	b.l7x4	3.8775	Yes	No	0	9	9
134	b.b9x3	b.l7x5	3.4175	Yes	No	0	6	6
135	b.l7x5	b.l9x1	3.14656	No	No	0	6	5
136	b.b8x1	b.b9x4	3.81687	No	No	0	8	9
137	b.b10x3	b.b8x1	3.46938	No	No	0	8	8
138	b.b11x4	b.b8x1	3.22156	Yes	No	0	9	8
139	b.b8x2	b.b8x4	4.29406	No	Yes	0	8	6
140	b.b8x2	b.b9x3	3.99625	No	Yes	0	8	6
141	b.b10x5	b.b8x3	3.92375	Yes	No	0	9	6
142	b.b8x3	b.l12x1	5.93406	No	No	0	6	6
143	b.b8x4	b.l8x10	5.95438	Yes	No	0	6	4
144	b.b8x5	b.l8x3	5.20937	No	No	0	4	3
145	b.l8x1	b.l8x8	4.0975	Yes	No	0	5	4
146	b.l8x3	b.l8x9	3.1125	No	No	0	3	3
147	b.l8x5	b.l8x7	6.12281	No	No	0	3	3
148	b.l8x5	b.l8x9	4.90625	No	No	0	3	3
149	b.b9x3	b.l8x10	3.70031	Yes	No	0	6	4
150	b.b12x6	b.b9x4	13.7369	Yes	No	0	8	9
151	b.b11x4	b.l9x3	6.165	Yes	Yes	2	9	9
152	b.b11x6	b.l9x3	16.0859	No	Yes	2	9	9
153	b.l11x2	b.l9x3	7.95563	Yes	Yes	2	9	9
154	b.b12x6	b.l9x3	4.10063	Yes	Yes	2	8	9
155	b.l11x2	b.l9x4	7.54469	Yes	No	0	9	5
156	b.l11x1	b.l9x6	4.02969	No	Yes	2	9	8
157	b.b14x1	b.l9x6	4.07688	No	Yes	0	8	8
158	G.s3h2.03	b.l9x6	7.43469	Yes	Yes	2	9	8
159	G.H2.02	b.l9x6	4.65094	Yes	Yes	2	8	8
160	G.H2.07	b.l9x6	7.32625	Yes	Yes	2	9	8
161	b.b10x1	b.b11x5	3.15812	No	Yes	0	9	6
162	b.b10x2	b.b10x4	3.8325	No	No	0	6	6
163	b.b10x2	b.b14x3	3.76594	No	Yes	0	6	5
164	b.b10x3	b.b11x2	3.47656	No	No	0	8	7
165	b.b10x4	b.b14x5	3.37719	No	No	0	6	5
166	b.b10x5	b.b11x2	6.86875	Yes	No	0	9	7
167	b.b11x1	b.l10x1	6.07187	No	No	0	5	3
168	b.b14x5	b.l10x1	3.67562	No	No	0	5	3
169	b.l10x1	b.l14x4	3.13063	No	No	0	3	1
170	b.b11x1	b.l10x2	8.1175	No	No	0	5	5
171	b.b12x7	b.l10x4	4.20781	No	No	0	9	3
172	b.l10x4	b.l12x2	5.54469	No	No	0	3	6
173	b.b11x2	b.l12x1	4.27906	No	No	0	7	6
174	b.b11x3	b.b14x3	4.98219	No	Yes	4	5	5
175	b.b11x3	b.b15x1	4.71094	No	Yes	4	5	9
176	b.b11x4	b.b12x6	9.51125	Yes	Yes	2	9	8
177	b.b11x5	b.b12x3	3.12	Yes	Yes	4	6	8
178	b.b11x5	b.l13x7	5.60469	Yes	No	4	6	9
179	b.b11x5	b.b14x3	4.59812	Yes	Yes	4	6	5
180	b.b11x6	b.l11x1	3.53656	No	No	2	9	9
181	b.b11x6	b.l11x2	8.37313	No	Yes	2	9	9
182	b.l11x1	b.l13x6	5.03031	No	Yes	2	9	9
183	b.b12x2	b.l11x2	9.03563	No	Yes	0	7	9
184	b.b12x2	b.l13x1	3.28719	No	No	0	7	2
185	b.b12x3	b.b13x7	3.9275	Yes	Yes	4	8	7
186	b.b12x3	b.l13x7	4.69469	Yes	No	4	8	9
187	b.b12x3	b.b15x1	3.27344	Yes	Yes	4	8	9
188	b.b12x3	b.b15x3	3.44	Yes	No	0	8	9
189	b.b12x4	b.b12x6	4.66187	No	Yes	2	4	8
190	b.b12x4	b.b13x3	3.5075	No	No	2	4	4
191	b.b12x5	b.b13x4	3.5	No	No	4	6	4
192	b.b12x5	b.b13x5	4.78875	No	No	4	6	4
193	b.b12x5	b.l16x1	3.21281	No	No	0	6	4
194	b.b12x6	b.b13x3	14.9222	Yes	No	2	8	4
195	b.b12x7	b.l12x3	9.30531	No	No	0	9	5
196	b.b13x2	b.l12x3	4.4725	No	No	0	4	5
197	b.b13x3	b.b13x6	5.13875	No	No	0	4	4
198	b.b13x4	b.b13x5	4.61188	No	No	4	4	4
199	b.b13x5	b.b13x7	7.13531	No	Yes	4	4	7
200	b.b13x7	b.b15x1	11.6222	Yes	Yes	4	7	9
201	b.b13x7	b.b16x6	15.9738	Yes	Yes	4	7	8
202	b.b13x7	b.b17x1	3.10687	Yes	No	0	7	4
203	b.l13x3	b.l13x7	5.10406	Yes	No	4	9	9
204	b.b15x3	b.l13x3	4.7075	No	Yes	0	9	9
205	b.b15x5	b.l13x3	7.59313	No	Yes	4	8	9
206	b.l13x3	b.l15x2	5.04	Yes	Yes	4	9	9
207	b.b16x2	b.l13x3	3.79219	No	Yes	4	5	9
208	b.b16x4	b.l13x3	17.1937	Yes	Yes	4	6	9
209	b.l13x4	b.l15x2	7.22687	No	Yes	0	3	9
210	b.l13x5	b.l15x2	3.56281	No	Yes	0	5	9
211	b.l13x6	b.l15x1	3.64813	Yes	No	2	9	7
212	G.H2.02	b.l13x6	3.22031	Yes	Yes	2	8	9
213	G.H2.03	b.l13x6	4.63125	No	Yes	0	9	9
214	G.H2.06	b.b14x1	9.72	Yes	No	0	9	8
215	b.b14x2	b.b18x3	6.045	No	Yes	0	7	8
216	b.b14x3	b.b15x1	4.79656	Yes	Yes	4	5	9
217	b.b14x4	b.b18x5	5.65812	No	Yes	0	8	5
218	b.l14x2	b.l18x4	3.48906	No	No	0	4	7
219	b.l14x3	b.l14x5	6.40281	No	No	0	5	5
220	b.l14x5	b.l16x2	6.86281	No	No	0	5	9
221	b.b16x5	b.l14x6	6.18563	No	No	0	5	3
222	b.b16x7	b.l14x6	3.435	Yes	No	0	9	3
223	b.b15x1	b.b16x6	11.9303	Yes	Yes	4	9	8
224	b.b15x2	b.b18x3	5.47219	No	Yes	5	6	8
225	b.b15x2	b.b18x5	8.56313	No	Yes	5	6	5
226	b.b15x2	b.b19x2	10.0387	No	Yes	5	6	6
227	b.b15x3	b.b16x6	5.86969	No	Yes	0	9	8
228	b.b15x4	b.l17x7	3.695	No	No	0	6	7
229	b.b15x5	b.l15x2	4.00406	No	Yes	4	8	9
230	b.l15x1	b.l17x6	7.78	No	Yes	2	7	9
231	G.H2.06	b.l15x1	4.14156	Yes	No	2	9	7
232	b.b16x2	b.l15x2	9.47969	No	Yes	4	5	9
233	b.b16x4	b.b16x6	7.0325	Yes	Yes	4	6	8
234	b.b16x4	b.b17x3	5.65719	Yes	No	4	6	5
235	b.b16x4	b.b17x6	12.7159	Yes	No	0	6	7
236	b.b16x5	b.b17x4	3.03656	No	No	0	5	5
237	b.b16x5	b.l20x1	4.975	No	No	0	5	6
238	b.b16x6	b.b17x3	5.305	Yes	No	4	8	5
239	b.b16x7	b.l16x3	8.97469	Yes	No	0	9	3
240	b.b16x7	b.b17x4	11.2431	Yes	No	0	9	5
241	b.b17x2	b.l16x3	6.21438	No	No	0	3	3
242	b.b17x2	b.b17x4	4.80656	No	No	0	3	5
243	b.b17x3	g.h1x10	3.19469	No	No	0	5	9
244	b.b17x5	b.b17x7	8.2	No	Yes	5	7	8
245	b.b17x5	b.b21x1	13.6225	No	Yes	5	7	7
246	b.b17x6	g.h1x14	7.27875	No	No	0	7	9
247	b.b17x7	b.b19x2	8.60719	Yes	Yes	5	8	6
248	b.b17x7	b.b20x6	11.6216	Yes	Yes	5	8	6
249	b.b17x7	b.b21x1	4.40469	Yes	Yes	5	8	7
250	b.l17x3	b.l17x7	7.125	Yes	No	5	9	7
251	b.b19x4	b.l17x3	7.2325	Yes	Yes	5	8	9
252	b.b19x6	b.l17x3	15.7366	No	Yes	5	9	9
253	b.l17x3	b.l19x2	3.74062	Yes	Yes	5	9	9
254	b.b20x4	b.l17x3	16.6072	Yes	Yes	5	8	9
255	b.l17x4	b.l19x2	9.33781	No	Yes	0	3	9
256	b.l17x5	b.l19x2	7.22344	No	Yes	0	6	9
257	b.l17x6	b.l19x1	7.19375	Yes	No	0	9	9
258	G.H2.05	b.l17x6	6.29281	No	Yes	2	7	9
259	G.H2.06	b.l17x6	9.5925	Yes	Yes	2	9	9
260	b.b19x4	b.l17x7	6.0325	Yes	No	5	8	7
261	b.b18x1	b.l19x1	9.75906	No	No	0	9	9
262	G.H2.06	b.b18x1	3.805	Yes	No	0	9	9
263	b.b18x2	b.b22x3	3.54938	No	No	0	5	6
264	b.b18x3	b.b19x2	6.35625	Yes	Yes	5	8	6
265	b.b18x3	b.b19x4	3.7525	Yes	Yes	5	8	8
266	b.b18x5	b.b19x2	3.48125	Yes	Yes	5	5	6
267	b.l18x1	b.l18x2	10.3813	Yes	Yes	9	6	7
268	b.l18x1	b.l18x3	4.68531	Yes	No	9	6	5
269	b.b19x1	b.l18x1	3.42188	No	Yes	0	6	6
270	b.b22x5	b.l18x1	7.53406	Yes	Yes	9	7	6
271	b.l18x1	b.l22x4	4.04813	Yes	No	9	6	9
272	b.l18x1	g.h2x8	9.78156	Yes	No	0	6	7
273	b.l18x1	g.h2x11	5.64313	Yes	Yes	9	6	6
274	b.b22x5	b.l18x2	4.15031	Yes	Yes	9	7	7
275	b.l18x2	b.l22x4	3.93313	Yes	No	9	7	9
276	b.l18x2	g.h2x11	4.64781	Yes	Yes	9	7	6
277	b.l18x3	b.l18x5	7.57781	No	No	0	5	2
278	b.l18x3	g.h2x11	11.2638	No	Yes	9	5	6
279	b.l18x5	b.l20x2	8.88906	No	No	0	2	9
280	b.b19x2	b.b20x6	10.9872	Yes	Yes	5	6	6
281	b.b19x3	b.b22x5	3.1175	No	Yes	9	4	7
282	b.b19x3	b.b23x2	3.00563	No	Yes	9	4	6
283	b.b19x4	b.b20x6	7.78031	Yes	Yes	5	8	6
284	b.b19x5	b.l21x9	5.565	No	No	0	5	6
285	b.b19x6	b.l19x2	7.03938	No	Yes	5	9	9
286	b.b20x2	b.l19x2	6.2775	Yes	Yes	5	6	9
287	b.b20x2	b.b20x4	5.335	Yes	Yes	5	6	8
288	b.b20x2	b.b21x6	3.33625	Yes	No	5	6	1
289	b.b20x2	b.l21x1	4.1	Yes	No	0	6	2
290	b.b20x3	b.b21x7	4.07344	No	Yes	0	8	5
291	b.b20x3	b.l21x9	3.93656	No	No	0	8	6
292	b.b20x4	b.b20x6	3.51	Yes	Yes	5	8	6
293	b.b20x4	b.b21x6	8.57031	Yes	No	5	8	1
294	b.b20x5	b.b21x4	4.36812	No	No	0	7	5
295	b.b20x5	b.b21x7	5.60188	No	Yes	0	7	5
296	b.b20x6	b.b21x3	3.78813	Yes	No	5	6	6
297	b.b20x7	b.l20x3	4.53344	No	No	0	9	7
298	b.b20x7	b.b21x4	4.87719	No	No	0	9	5
299	b.b20x7	g.h2x4	4.67844	No	No	0	9	7
300	b.l20x2	g.l1x5	6.42063	No	No	0	9	4
301	b.l20x2	g.h2x7	8.48844	No	No	0	9	5
302	b.b21x1	g.l1x4	12.2838	Yes	No	0	7	8
303	b.b21x2	g.h2x1	4.255	No	No	0	6	8
304	b.b21x5	b.b21x7	4.63938	No	Yes	0	4	5
305	b.b21x7	b.b23x2	4.68969	Yes	Yes	0	5	6
306	b.b21x7	b.b24x6	12.8713	Yes	Yes	0	5	8
307	b.l21x2	b.l21x4	6.06	Yes	No	0	4	4
308	b.l21x2	b.l21x5	5.79969	Yes	No	0	4	4
309	b.b24x6	b.l21x2	4.82812	Yes	Yes	0	8	4
310	b.b25x3	b.l21x2	9.06344	No	Yes	0	5	4
311	b.b23x6	b.l21x5	6.30813	Yes	No	0	7	4
312	b.l21x7	b.l23x1	5.98	No	Yes	0	5	6
313	b.l21x7	b.l23x2	5.7375	No	Yes	0	5	8
314	b.l21x8	b.l23x1	3.03906	No	Yes	0	4	6
315	b.b23x6	b.l21x9	8.38469	Yes	No	0	7	6
316	b.b22x1	b.l23x1	4.51656	No	Yes	0	8	6
317	b.b22x2	b.b26x3	4.505	No	No	0	8	6
318	b.b22x3	b.b23x2	3.02656	No	Yes	0	6	6
319	b.b22x4	b.b26x5	3.48594	No	No	0	5	7
320	b.b22x5	b.b23x2	8.22094	Yes	Yes	9	7	6
321	b.b23x1	b.l22x1	3.75094	No	No	0	5	9
322	b.l22x1	g.ctx3	8.18906	No	Yes	8	9	9
323	b.l22x3	g.ctx3	9.61938	No	Yes	0	9	9
324	b.b24x7	b.l22x5	11.8353	Yes	Yes	8	9	9
325	b.l22x5	b.l24x2	6.26125	Yes	Yes	0	9	6
326	b.l22x5	g.ctx6	4.13562	Yes	No	8	9	6
327	b.b23x3	b.b24x5	3.53875	No	Yes	0	7	5
328	b.b23x3	b.b26x3	3.93563	No	No	0	7	6
329	b.b23x3	b.b27x1	4.65625	No	No	0	7	6
330	b.b23x4	b.b23x6	4.41937	No	Yes	0	6	7
331	b.b23x5	b.b24x3	3.43	No	No	0	7	5
332	b.b23x6	b.l23x2	3.80906	Yes	Yes	7	7	8
333	b.b23x6	b.b24x4	11.1941	Yes	Yes	7	7	6
334	b.b23x6	b.b24x6	6.54156	Yes	Yes	7	7	8
335	b.l23x1	b.l25x6	18.2766	Yes	No	0	6	8
336	b.b24x2	b.l23x2	8.58438	No	Yes	0	5	8
337	CT	b.l23x2	4.4675	Yes	Yes	7	5	8
338	b.b24x3	b.b25x7	4.3125	No	No	0	5	7
339	b.b24x3	b.l25x7	4.375	No	No	0	5	7
340	b.b24x4	b.b24x6	4.55531	Yes	Yes	7	6	8
341	b.b24x4	b.b25x3	9.15187	Yes	No	0	6	5
342	b.b24x4	b.b25x6	4.20344	Yes	No	0	6	3
343	b.b24x7	b.l24x3	8.16594	Yes	No	8	9	5
344	b.b24x7	b.b25x2	3.15906	Yes	No	8	9	2
345	b.b25x2	b.l24x3	4.06219	No	No	8	2	5
346	b.b25x7	b.b28x6	15.5188	No	Yes	0	7	9
347	b.l25x3	b.l25x7	3.33	Yes	No	0	9	7
348	b.b27x3	b.l25x3	6.59219	No	Yes	0	8	9
349	b.b27x5	b.l25x3	14.4716	No	Yes	11	9	9
350	b.l25x3	b.l28x2	9.49281	Yes	Yes	11	9	9
351	b.b28x4	b.l25x3	10.48	Yes	Yes	11	6	9
352	b.l25x4	b.l28x2	6.02719	No	Yes	0	5	9
353	I1x48	b.l25x4	4.01688	No	No	0	7	5
354	b.l25x5	b.l28x1	8.96938	No	Yes	0	7	9
355	b.l25x6	b.l28x1	23.8962	No	Yes	0	8	9
356	b.b26x1	b.b26x2	3.44	No	No	0	9	7
357	b.b26x1	b.l28x1	4.36156	No	Yes	0	9	9
358	b.b26x3	b.b27x3	3.03938	No	No	0	6	8
359	b.b26x5	b.b27x1	4.10938	No	No	0	7	6
360	b.l27x1	b.l27x3	5.33313	No	No	14	7	7
361	b.l27x3	b.l27x5	8.40438	No	No	0	7	5
362	b.l27x5	g.ctx4	4.82156	No	No	0	5	7
363	b.l27x5	g.ctx15	5.03344	No	Yes	0	5	9
364	b.l27x6	g.ctx16	4.85281	No	Yes	0	7	8
365	b.b27x1	g.ctx5	3.11969	No	No	0	6	9
366	b.b27x3	b.b28x6	7.92062	No	Yes	0	8	9
367	b.b27x5	b.l28x2	8.78719	No	Yes	11	9	9
368	G.H2.09	b.l28x1	4.76281	Yes	Yes	2	8	9
369	b.b28x2	b.l28x2	7.98875	No	Yes	0	4	9
370	b.b28x4	b.b28x6	6.27125	Yes	Yes	11	6	9
371	b.b28x5	g.ctx16	4.47469	No	Yes	3	5	8
372	b.b28x7	g.ctx14	9.83406	No	Yes	3	9	9
373	b.b28x7	g.ctx16	3.73531	No	Yes	3	9	8
374	g.h1x1	g.h1x5	4.61906	No	No	0	2	6
375	g.h1x10	g.h1x14	6.92937	No	No	0	9	9
376	g.l1x2	g.l1x4	4.38344	No	No	0	2	8
377	g.h2x3	g.l1x5	5.22594	No	No	0	5	4
378	g.h2x11	g.h2x15	15.8563	Yes	No	0	6	6
379	g.ctx3	g.ctx4	4.57844	Yes	No	0	9	7
380	g.ctx3	g.ctx5	3.56375	Yes	No	8	9	9
381	g.ctx3	g.ctx6	8.10031	Yes	No	8	9	6
382	g.ctx10	g.ctx9	4.36031	No	No	3	5	6
383	g.ctx13	g.ctx9	3.34187	No	No	3	5	6
384	g.ctx14	g.ctx9	3.27688	Yes	No	3	9	6
385	g.ctx10	g.ctx13	5.10875	No	No	3	5	5
386	g.ctx12	g.ctx13	4.22187	No	No	0	6	5
387	g.ctx14	g.ctx15	5.80687	Yes	Yes	3	9	9
388	g.ctx14	g.ctx16	3.35906	Yes	Yes	3	9	8
389	g.ctx15	g.ctx16	3.97031	Yes	Yes	3	9	8
390	g.ctx17	g.ctx18	7.30375	No	No	0	7	6
391	1x30	1x31	4.64594	No	No	0	4	6
392	1x39	2x61	5.34375	No	No	0	6	8
393	1x39	7x39	9.4775	No	Yes	0	6	8
394	1x43	2x57	3.69594	Yes	Yes	0	7	8
395	1x43	2x58	5.06812	Yes	No	0	7	9
396	1x46	2x54	3.40875	No	No	0	8	8
397	1x46	2x57	3.10594	No	Yes	0	8	8
398	1x46	7x47	5.24875	No	No	0	8	8
399	1x50	2x50	7.10875	No	Yes	0	9	9
400	1x50	7x50	9.06219	No	No	0	9	9
401	1x52	8x54	6.325	No	No	0	8	9
402	1x53	2x47	3.995	No	No	0	9	9
403	1x55	8x57	4.01	No	No	0	6	8
404	1x56	8x50	3.92656	No	Yes	0	9	9
405	1x57	I1x51	3.11125	No	No	0	8	7
406	1x57	2x44	4.84844	No	No	0	8	7
407	1x60	I1x49	4.32719	Yes	No	0	8	7
408	1x60	I1x50	4.09656	Yes	No	7	8	9
409	1x60	8x53	5.7775	Yes	No	0	8	8
410	2x40	I1x50	3.09094	No	No	7	9	9
411	8x50	I1x50	3.35	Yes	No	7	9	9
412	2x37	2x40	6.29437	No	No	0	8	9
413	2x38	I2x57	4.29531	No	No	0	7	8
414	2x39	G.H5.23	3.05969	No	Yes	0	8	4
415	2x40	8x50	3.3225	No	Yes	7	9	9
416	2x42	3x45	5.27844	Yes	No	0	8	7
417	2x42	3x46	3.56125	Yes	No	0	8	9
418	2x42	3x49	11.1322	Yes	No	0	8	9
419	2x42	4x46	4.31813	Yes	No	0	8	9
420	2x45	3x42	5.70187	No	No	15	9	8
421	2x45	4x46	7.74	No	No	0	9	9
422	2x45	4x50	4.09	No	Yes	15	9	9
423	2x46	2x50	4.36687	No	Yes	1	9	9
424	2x46	3x43	4.70844	No	Yes	1	9	8
425	2x46	7x49	7.93687	No	Yes	1	9	9
426	2x50	3x39	4.64656	Yes	No	0	9	9
427	2x50	7x46	7.31313	Yes	No	0	9	9
428	2x50	7x49	7.48812	Yes	Yes	1	9	9
429	2x52	3x35	5.54531	No	No	0	8	7
430	2x53	3x35	3.1675	No	No	0	8	7
431	2x53	7x46	5.24062	No	No	0	8	9
432	2x551	3x31	4.62781	No	No	0	6	6
433	2x56	3x32	8.70062	No	No	1	8	9
434	2x56	7x42	3.75281	No	Yes	1	8	8
435	2x57	7x39	3.35	Yes	Yes	1	8	8
436	2x57	7x42	6.8425	Yes	Yes	1	8	8
437	2x59	3x28	9.86469	No	Yes	0	7	7
438	2x60	2x64	3.68313	Yes	No	0	7	7
439	2x60	3x28	4.27625	Yes	Yes	0	7	7
440	2x60	7x38	5.68531	Yes	Yes	1	7	7
441	2x60	7x42	5.55406	Yes	Yes	1	7	8
442	2x63	E1x50	8.63	No	Yes	1	7	9
443	2x64	7x35	3.85969	No	No	0	7	6
444	E1x49	E2	4.21781	No	Yes	0	5	5
445	E1x50	E1x52	11.0109	Yes	Yes	0	9	7
446	3x25	E1x50	6.85875	No	Yes	1	9	9
447	3x28	E1x50	3.58938	Yes	Yes	0	7	9
448	E1x50	E2x50	11.8594	Yes	No	1	9	9
449	3x22	3x26	4.08875	No	No	0	4	7
450	3x22	E2	13.5756	No	Yes	1	4	5
451	3x25	E2x50	7.16625	No	No	1	9	9
452	3x28	3x29	4.11625	Yes	No	0	7	7
453	3x30	4x62	3.89875	No	No	0	8	6
454	3x32	7x42	6.82562	No	Yes	1	9	8
455	3x32	Lig	7.34875	No	Yes	1	9	0
456	3x33	4x57	10.2838	No	No	0	8	8
457	3x33	4x61	3.15188	No	No	0	8	7
458	3x33	Lig	9.68906	No	Yes	1	8	0
459	3x34	4x53	3.22594	No	No	0	8	8
460	3x34	4x54	3.59375	No	No	0	8	6
461	3x36	6x48	4.34125	No	Yes	1	8	8
462	3x36	Lig	8.56906	No	Yes	1	8	0
463	3x37	3x41	4.52094	Yes	No	0	8	7
464	3x37	4x53	3.84969	Yes	No	0	8	8
465	3x37	4x57	4.71062	Yes	No	0	8	8
466	3x37	5x461	4.30062	Yes	No	0	8	8
467	3x37	Lig	4.46125	Yes	Yes	1	8	0
468	3x38	4x50	10.74	No	Yes	0	8	9
469	3x38	4x53	4.24375	No	No	0	8	8
470	3x40	6x48	6.61219	No	Yes	0	9	8
471	3x42	4x50	3.21563	No	Yes	15	8	9
472	3x43	5x54	3.08937	Yes	No	1	8	9
473	3x43	6x44	3.24437	Yes	Yes	1	8	9
474	3x43	7x49	4.78969	Yes	Yes	1	8	9
475	3x43	7x53	5.11688	Yes	Yes	1	8	9
476	3x44	5x53	4.73438	No	No	0	7	7
477	3x46	3x50	4.13594	No	Yes	1	9	9
478	3x46	7x53	4.3375	No	Yes	1	9	9
479	3x47	5x54	5.72937	No	No	0	9	9
480	3x47	5x57	3.59125	No	No	0	9	8
481	3x47	5x58	7.41719	No	Yes	0	9	9
482	3x48	5x57	5.39625	No	No	0	7	8
483	3x49	I2x57	6.19625	No	No	0	9	8
484	3x49	G.H5.23	4.55406	No	Yes	0	9	4
485	3x50	5x58	5.20813	Yes	Yes	0	9	9
486	3x50	7x53	5.85625	Yes	Yes	1	9	9
487	3x50	G.H5.23	10.7053	Yes	Yes	0	9	4
488	3x51	3x55	12.6194	No	No	0	8	8
489	3x51	5x57	9.57	No	No	0	8	8
490	3x51	5x60	6.71875	No	No	0	8	7
491	3x52	I2x53	3.77781	No	No	0	7	9
492	3x53	G.H5.19	5.09875	No	No	0	9	8
493	3x53	G.H5.23	4.97906	No	Yes	0	9	4
494	3x54	G.H5.20	3.805	No	Yes	0	8	8
495	G.H5.12	I2x50	3.53437	No	No	0	7	8
496	G.H5.12	I2x51	4.1775	No	No	0	7	7
497	G.H5.15	I2x51	4.12719	No	No	0	8	7
498	I2x52	I2x56	4.59969	No	No	0	7	6
499	I2x53	I2x57	6.50094	No	No	0	9	8
500	G.S1.02	I2x54	4.09938	No	No	0	5	7
501	4x57	5x43	3.29719	No	No	0	8	8
502	4x61	E2x52	4.12531	No	Yes	0	7	7
503	4x64	E2	9.73344	No	Yes	1	7	5
504	E2	E2	62.7838	Yes	Yes	1	5	5
505	E2	E2x51	12.5359	Yes	No	0	5	4
506	E2	E2x52	9.43875	Yes	Yes	1	5	7
507	5x36	E2	8.47	No	Yes	0	7	5
508	5x39	E2	4.45187	No	Yes	1	8	5
509	5x39	5x43	4.17438	No	No	1	8	8
510	5x40	6x59	3.18156	No	No	0	7	8
511	5x47	5x48	7.57406	Yes	No	0	9	7
512	5x47	5x51	5.71063	Yes	No	0	9	7
513	5x47	6x48	3.24625	Yes	Yes	1	9	8
514	5x47	6x49	4.10437	Yes	Yes	0	9	7
515	5x47	6x52	16.4625	Yes	Yes	1	9	8
516	5x51	6x44	4.85938	No	Yes	0	7	9
517	5x51	6x45	3.70594	No	No	0	7	7
518	5x54	6x44	5.60375	No	Yes	1	9	9
519	5x55	6x41	3.9975	No	No	0	5	7
520	5x56	5x60	3.34438	No	No	0	5	7
521	5x58	6x37	6.17688	Yes	No	0	9	9
522	5x58	6x40	3.41594	Yes	Yes	0	9	8
523	5x58	6x41	5.66938	Yes	No	0	9	7
524	5x62	5x66	4.73	Yes	No	0	7	7
525	5x62	6x34	4.88719	Yes	No	0	7	8
526	5x65	G.H5.20	3.265	No	Yes	0	8	8
527	6x36	7x56	5.68594	No	No	0	8	8
528	6x40	7x53	5.63719	Yes	Yes	0	8	9
529	6x44	6x48	6.73344	Yes	Yes	1	9	8
530	6x45	6x49	3.27688	No	Yes	0	7	7
531	6x47	7x45	7.38438	No	No	0	8	9
532	6x48	6x52	3.39094	Yes	Yes	1	8	8
533	6x48	7x41	8.45875	Yes	No	0	8	8
534	6x48	7x45	8.77938	Yes	No	0	8	9
535	6x48	Lig	5.51937	Yes	Yes	1	8	0
536	6x49	6x50	3.87313	Yes	No	0	7	9
537	6x50	7x40	3.98125	No	No	0	9	8
538	6x51	6x52	4.67281	Yes	Yes	1	8	8
539	6x51	6x55	3.79844	Yes	No	1	8	8
540	6x51	7x38	4.50063	Yes	Yes	1	8	7
541	6x51	Lig	12.1169	Yes	Yes	1	8	0
542	6x52	Lig	3.38094	Yes	Yes	1	8	0
543	6x54	7x33	4.45375	No	No	0	6	5
544	6x61	E3	6.19	No	Yes	0	6	6
545	7x34	7x38	3.43062	No	Yes	1	7	7
546	7x38	7x42	4.14094	Yes	Yes	1	7	8
547	7x38	Lig	7.41875	Yes	Yes	1	7	0
548	7x39	7x42	6.45875	Yes	Yes	1	8	8
549	7x42	Lig	5.23594	Yes	Yes	1	8	0
550	7x45	7x49	6.40063	No	Yes	0	9	9
551	7x54	8x50	3.01937	Yes	Yes	0	8	9
552	8x52	8x55	3.18531	No	No	0	6	6
553	CT	CT	4.8325	Yes	Yes	7	5	5
554	G.HN.11	G.HN.33	3.95719	No	Yes	0	2	4
555	G.HN.30	G.HN.33	4.72094	No	Yes	0	7	4
556	G.HN.37	G.HN.41	3.55031	No	No	0	3	4
557	G.S1.01	G.S3.02	4.09937	No	No	0	7	4
558	G.S1.01	G.S3.04	10.0691	No	Yes	0	7	7
559	G.S1.02	G.S3.03	6.16656	No	Yes	0	5	7
560	G.S1.02	G.h2s4.05	4.74563	No	No	0	5	7
561	G.S1.03	G.S3.04	4.60344	No	Yes	0	9	7
562	G.S1.04	G.S3.03	3.57656	Yes	Yes	0	6	7
563	G.S1.04	G.S3.05	3.53594	Yes	Yes	10	6	7
564	G.S1.04	G.S4.01	4.08063	Yes	No	0	6	8
565	G.S1.04	G.S4.03	4.06187	Yes	No	10	6	7
566	G.S1.05	G.S1.07	5.27781	No	No	0	9	9
567	G.S1.05	G.h2s4.01	10.8106	No	Yes	0	9	9
568	G.H1.01	G.S1.06	3.70125	Yes	No	10	9	8
569	G.S1.06	G.S3.07	4.24031	No	Yes	10	8	9
570	G.S1.07	G.S4.04	4.64375	No	No	2	9	9
571	G.H3.12	G.S1.07	4.45906	Yes	No	2	7	9
572	G.H3.08	G.s1h1.02	3.63812	No	No	0	9	8
573	G.H3.01	G.s1h1.04	5.23438	Yes	No	0	9	9
574	G.S4.05	G.s1h1.05	3.75437	No	No	0	7	9
575	G.H1.01	G.S3.07	8.59625	Yes	Yes	10	9	9
576	G.H1.04	G.H1.08	4.97594	Yes	No	6	7	9
577	G.H1.04	G.S4.05	6.35812	Yes	No	6	7	7
578	G.H1.04	G.S5.05	6.43125	Yes	Yes	6	7	9
579	G.H1.04	G.H5.03	3.17313	Yes	Yes	6	7	8
580	G.H1.05	G.S2.04	11.22	No	Yes	0	6	7
581	G.H1.08	G.S2.06	4.23812	No	Yes	0	9	8
582	G.H1.08	G.H5.03	3.06656	No	Yes	6	9	8
583	G.H1.09	G.S2.06	3.00656	No	Yes	0	7	8
584	G.H1.11	G.H5.01	3.7525	No	No	0	8	9
585	G.H1.12	G.S2.06	3.78219	No	Yes	0	8	8
586	G.S2.01	G.S3.08	5.085	No	No	0	9	9
587	G.S2.02	G.S2.04	11.1447	No	Yes	10	5	7
588	G.S2.02	G.S3.07	4.4625	No	Yes	10	5	9
589	G.S2.03	G.S3.04	11.6684	No	Yes	0	9	7
590	G.S2.03	G.S3.06	4.23281	No	No	2	9	6
591	G.S2.04	G.S3.07	3.91656	Yes	Yes	10	7	9
592	G.S2.05	G.S3.04	5.04688	No	Yes	0	3	7
593	G.S2.06	G.S3.05	5.36625	Yes	Yes	0	8	7
594	G.H5.04	G.S2.06	4.43469	No	Yes	0	7	8
595	G.H5.04	G.S2.08	3.74844	No	No	0	7	5
596	G.H5.08	G.S2.08	4.07406	No	No	0	8	5
597	G.H5.08	G.s2s3.01	7.85375	No	No	0	8	4
598	G.S3.01	G.S3.03	3.77969	No	Yes	0	4	7
599	G.H5.11	G.S3.03	5.77625	No	Yes	0	8	7
600	G.S3.05	G.S4.03	5.59312	Yes	No	10	7	7
601	G.S3.06	G.h2s4.01	3.84812	No	Yes	2	6	9
602	G.H2.07	G.S3.08	5.40156	Yes	No	0	9	9
603	G.H2.02	G.s3h2.03	3.73469	Yes	Yes	2	8	9
604	G.H2.07	G.s3h2.03	7.39687	Yes	Yes	2	9	9
605	G.H2.02	G.H2.07	5.25187	Yes	Yes	2	8	9
606	G.H2.03	G.H2.05	10.6478	No	No	0	9	7
607	G.H2.04	G.H2.07	5	Yes	Yes	2	9	9
608	G.H2.04	G.H3.12	3.13156	Yes	Yes	2	9	7
609	G.H2.04	G.H3.15	4.08375	Yes	Yes	2	9	8
610	G.H2.05	G.H2.06	3.75187	No	Yes	2	7	9
611	G.H2.08	G.H3.15	3.92875	No	Yes	2	8	8
612	G.H2.08	G.H3.17	4.40625	No	No	0	8	5
613	G.H2.08	G.H3.18	4.7875	No	Yes	2	8	9
614	G.H2.09	G.H3.17	6.08469	Yes	No	0	8	5
615	G.H2.10	G.h2s4.01	3.44938	Yes	Yes	2	7	9
616	G.H3.17	G.h2s4.02	6.33594	No	Yes	0	5	7
617	G.S4.01	G.S5.03	6.19	No	No	0	8	8
618	G.H3.18	G.S4.02	9.46031	Yes	No	2	9	7
619	G.S4.02	G.h3s5.03	3.14563	No	No	2	7	7
620	G.H5.07	G.S4.03	3.325	No	No	0	8	7
621	G.H3.09	G.S4.04	14.1994	Yes	No	0	9	9
622	G.H3.12	G.S4.04	4.39656	Yes	No	2	7	9
623	G.S4.05	G.S5.07	3.69094	No	Yes	6	7	9
624	G.H4.15	G.S4.06	7.70219	No	No	0	9	7
625	G.S4.07	G.s4h3.03	3.34906	No	Yes	0	8	7
626	G.S5.06	G.s4h3.01	7.69656	No	No	0	8	7
627	G.HG.04	G.s4h3.01	5.83813	No	No	0	8	7
628	G.H4.11	G.s4h3.01	3.78938	No	No	0	8	7
629	G.s4h3.02	G.s5hg.01	3.15562	No	No	6	9	9
630	G.HG.03	G.s4h3.02	5.67625	No	No	6	5	9
631	G.s4h3.03	G.s4h3.06	9.75437	Yes	No	16	7	9
632	G.H3.01	G.s4h3.03	13.8831	Yes	Yes	16	9	7
633	G.s4h3.04	G.s4h3.05	8.33187	Yes	No	12	8	9
634	G.HG.04	G.s4h3.04	3.91937	No	Yes	0	8	8
635	G.HG.07	G.s4h3.04	7.7975	Yes	Yes	12	9	8
636	G.HG.08	G.s4h3.04	3.55156	No	Yes	0	6	8
637	G.HG.15	G.s4h3.04	6.04344	No	Yes	0	6	8
638	G.HG.07	G.s4h3.05	7.86531	Yes	No	12	9	9
639	G.hgh4.01	G.s4h3.05	9.80781	No	No	0	5	9
640	G.H3.01	G.s4h3.06	9.82031	Yes	No	16	9	9
641	G.H3.04	G.s4h3.14	5.23563	No	No	0	9	6
642	G.H3.03	G.s4h3.15	5.05219	No	No	0	4	9
643	G.hgh4.02	G.s4h3.15	3.24531	Yes	No	0	8	9
644	G.H3.02	G.hgh4.02	4.04437	No	Yes	0	8	8
645	G.H3.02	G.H4.11	3.8725	No	No	0	8	8
646	G.H3.03	G.H3.06	6.53906	No	Yes	0	4	7
647	G.H3.06	G.H4.14	7.425	Yes	No	0	7	5
648	G.H3.06	G.H4.15	4.65	Yes	No	0	7	9
649	G.H3.09	G.H3.13	6.24031	Yes	No	0	9	5
650	G.H3.09	G.S5.04	4.07125	Yes	No	0	9	8
651	G.H3.10	G.h4s6.01	5.69281	No	No	0	5	3
652	G.H3.12	G.H3.15	3.62875	Yes	Yes	2	7	8
653	G.H3.13	G.S5.02	4.70406	No	No	0	5	6
654	G.H3.15	G.H3.16	3.38812	Yes	No	0	8	4
655	G.H3.15	G.H3.18	4.02812	Yes	Yes	2	8	9
656	G.H3.18	G.h3s5.03	4.29031	Yes	No	2	9	7
657	G.S5.01	G.S6.02	4.45219	No	Yes	17	8	8
658	G.H5.14	G.S5.01	8.94094	No	No	17	6	8
659	G.S5.02	G.S6.01	3.33875	No	No	0	6	6
660	G.S5.03	G.S5.05	3.49375	No	Yes	0	8	9
661	G.H5.10	G.S5.03	3.70563	No	No	0	7	8
662	G.S5.04	G.S5.06	3.76156	No	No	0	8	8
663	G.S5.05	G.S6.04	3.18125	Yes	Yes	6	9	9
664	G.S5.05	G.s6h5.01	3.80875	Yes	Yes	6	9	9
665	G.H5.03	G.S5.05	3.36125	Yes	Yes	6	8	9
666	G.S5.06	G.S6.05	7.04281	No	No	0	8	5
667	G.S5.07	G.s5hg.01	5.6375	Yes	No	6	9	9
668	G.S5.07	G.s6h5.01	5.71219	Yes	Yes	6	9	9
669	G.HG.03	G.s5hg.01	3.56906	No	No	6	5	9
670	G.HG.01	G.s6h5.02	3.63969	No	Yes	0	5	7
671	G.HG.12	G.HG.13	3.73594	No	No	12	3	6
672	G.HG.14	G.HG.17	5.75156	No	No	0	5	3
673	G.H4.01	G.HG.14	10.8953	No	No	0	3	5
674	G.H4.02	G.HG.14	4.16062	No	No	0	3	5
675	G.HG.15	G.hgh4.05	9.20344	No	No	0	6	6
676	G.H4.01	G.HG.16	4.20969	No	No	0	3	4
677	G.HG.17	G.hgh4.01	5.42406	No	No	0	3	5
678	G.H4.14	G.hgh4.02	7.15312	No	Yes	0	5	8
679	G.hgh4.03	G.hgh4.04	5.35281	No	No	0	6	5
680	G.hgh4.05	G.hgh4.07	5.11094	No	No	0	6	8
681	G.H4.10	G.hgh4.05	11.2094	No	No	0	7	6
682	G.hgh4.07	G.hgh4.08	4.06	No	No	0	8	3
683	G.H4.03	G.hgh4.08	9.76062	No	No	0	5	3
684	G.H4.03	G.H4.06	4.68156	No	No	0	5	5
685	G.H4.05	G.H4.08	7.84938	No	No	0	3	5
686	G.H4.05	G.H4.09	3.94281	No	No	0	3	3
687	G.H4.08	G.S6.05	12.4263	No	No	0	5	5
688	G.H4.12	G.S6.03	7.74406	No	No	0	5	5
689	G.H4.12	G.S6.05	4.75594	No	No	0	5	5
690	G.H4.13	G.H4.17	8.08125	No	No	0	2	4
691	G.h4s6.08	G.h4s6.09	4.78813	No	No	0	7	4
692	G.S6.02	G.h4s6.20	9.89531	Yes	No	0	8	4
693	G.H5.06	G.S6.02	3.18906	No	Yes	0	4	8
694	G.H5.10	G.S6.02	4.7525	No	Yes	0	7	8
695	G.H5.13	G.S6.02	9.26875	Yes	Yes	0	7	8
696	G.H5.14	G.S6.02	4.17625	No	Yes	17	6	8
697	G.S6.04	G.s6h5.01	3.98156	Yes	Yes	6	9	9
698	G.S6.04	G.s6h5.05	3.66188	Yes	Yes	6	9	9
699	G.H5.06	G.S6.04	13.7534	No	Yes	0	4	9
700	G.s6h5.01	G.s6h5.05	4.02187	Yes	Yes	6	9	9
701	G.H5.03	G.s6h5.01	7.58687	Yes	Yes	6	8	9
702	G.s6h5.02	G.s6h5.05	4.13406	Yes	Yes	0	7	9
703	G.H5.03	G.s6h5.05	7.025	Yes	Yes	6	8	9
704	G.H5.01	G.H5.02	3.48156	No	No	0	9	4
705	G.H5.02	G.H5.05	11.3775	No	No	0	4	5
706	G.H5.08	G.H5.12	3.83656	No	No	0	8	7
707	G.H5.16	G.H5.20	3.15594	No	Yes	0	6	8
708	G.H5.20	G.H5.25	3.72125	Yes	No	0	8	8
709	b.1x19	b.b21x1	3.1275	No	Yes	0	6	7
710	b.lh12x2	g.l1x6	7.00063	No	No	0	8	4
711	b.l22x5	b.lhb1x3	3.40781	Yes	No	0	9	2
712	b.b4x4	b.b5x3	4.58844	No	Yes	3	8	9
713	G.H2.07	b.l13x6	4.1875	Yes	Yes	2	9	9
714	b.b18x5	b.l14x1	3.16344	Yes	No	0	5	4
715	b.b16x7	b.l16x2	4.80281	Yes	No	0	9	9
716	b.b20x4	b.b21x3	11.485	Yes	No	5	8	6
717	b.l22x1	g.ctx5	3.37813	No	No	8	9	9
718	b.b23x1	b.b24x5	3.63188	No	Yes	0	5	5
719	b.b24x2	b.b25x6	3.09219	No	No	0	5	3
720	I1x51	b.l25x4	5.3575	No	No	0	7	5
721	G.h2s4.02	b.l28x1	3.16781	Yes	Yes	2	7	9
722	g.h2x3	g.h2x7	3.80219	No	No	0	5	5
723	2x42	4x45	3.7475	Yes	No	0	8	7
724	2x43	7x54	3.0325	No	Yes	0	9	8
725	2x59	E1x52	4.24531	No	Yes	0	7	7
726	3x24	E1x52	4.74187	No	Yes	0	6	7
727	3x52	I2x52	4.265	No	No	0	7	7
728	I2x54	I2x56	3.5175	No	No	0	7	6
729	4x41	I2x56	4.40969	No	No	0	8	6
730	E2	E3	6.2325	Yes	Yes	1	5	6
731	5x40	6x55	5.16031	No	No	0	7	8
732	5x67	6x29	4.0875	No	No	0	5	0
733	5x68	6x30	4.72188	No	No	0	8	9
734	6x39	7x52	3.10687	No	No	0	8	8
735	6x57	E3	3.14031	No	Yes	0	6	6
736	6x58	7x30	3.115	No	No	0	5	6
737	G.H1.04	G.S5.07	3.96469	Yes	Yes	6	7	9
738	G.H1.04	G.s6h5.01	3.72844	Yes	Yes	6	7	9
739	G.hfs2.06	G.s3h2.03	3.5425	No	Yes	0	8	9
740	G.H2.09	G.H2.10	3.04031	Yes	Yes	2	8	7
741	G.H3.02	G.s4h3.03	3.21438	No	Yes	0	8	7
742	G.H3.05	G.s4h3.03	3.50406	No	Yes	0	8	7
743	G.HG.13	G.s4h3.04	3.26062	No	Yes	12	6	8
744	G.s4h3.12	G.s4h3.13	3.82812	No	No	0	4	4
745	G.H3.06	G.h4s6.01	3.78938	Yes	No	0	7	3
746	G.H3.09	G.H4.15	5.49281	Yes	No	0	9	9
747	G.HG.07	G.HG.12	3.05875	Yes	No	12	9	3
748	G.HG.07	G.HG.13	3.29906	Yes	No	12	9	6
749	G.hgh4.02	G.hgh4.04	3.57188	Yes	No	0	8	5
750	G.H4.10	G.H4.14	5.90781	No	No	0	7	5
751	G.S6.01	G.h4s6.08	3.88281	No	No	0	6	7
752	G.H5.02	G.s6h5.05	3.93813	No	Yes	0	4	9
753	2x63	Lig	3.11812	No	Yes	1	7	0
754	3x29	4x65	6.41625	No	No	0	7	7
755	3x50	G.H5.25	4.63062	Yes	No	0	9	8
756	3x55	5x64	3.21125	No	No	0	8	7
757	4x65	E2x52	3.90875	No	Yes	0	7	7
758	E2	Lig	16.8766	Yes	Yes	1	5	0
759	E2x52	Lig	5.0575	Yes	Yes	1	7	0
760	5x35	E2	3.8625	No	Yes	0	0	5
761	6x55	Lig	4.12063	No	Yes	1	8	0
762	6x58	Lig	5.63688	No	Yes	1	5	0
763	E3	Lig	4.81375	Yes	Yes	1	6	0
764	7x34	Lig	5.61219	No	Yes	1	7	0
765	b.l13x6	b.l9x6	3.48438	Yes	Yes	2	9	8
766	Lig	Lig	17.3556	Yes	Yes	1	0	0
767	G.h4s6.10	G.h4s6.13	3.1975	No	No	0	4	7
768	8x50	G.H5.24	3.73719	Yes	No	0	9	7
769	2x60	Lig	4.59031	Yes	Yes	1	7	0
770	5x43	Lig	3.92594	No	Yes	1	8	0
771	G.H3.01	G.s4h3.08	3.1125	Yes	No	0	9	0
772	E2	NT	9.8575	Yes	Yes	1	5	0
773	NT	NT	3.69062	Yes	Yes	1	0	0
774	Lig	NT	3.08313	Yes	Yes	1	0	0
775	E1	Lig	4.59562	No	Yes	0	0	0
776	7x31	Lig	6.5975	No	Yes	0	3	0
777	H.HC.11	H.HE.06	4.19938	No	No	0	0	0
778	H.HD.07	H.HD.10	3.08625	Yes	No	0	0	0
779	H.HD.09	H.HD.12	4.5075	No	No	0	0	0
780	H.HD.11	H.HD.12	3.19875	No	No	0	0	0
781	H.hdhe.01	H.hdhe.03	3.22375	No	No	0	0	0
782	H.HE.03	H.HE.07	3.4975	No	No	0	0	0
783	H.HE.04	H.HF.06	4.3725	No	No	0	0	0
784	b.b6x1	b.l7x1	3.00031	No	No	0	9	9
785	3x44	5x50	3	No	No	0	7	9
786	G.H2.04	G.H3.08	2.99531	Yes	No	0	9	9
787	1x32	2x67	2.97687	No	No	0	4	6
788	5x49	5x50	2.975	No	No	0	7	9
789	G.S1.06	G.S3.05	2.95937	No	Yes	10	8	7
790	H.HC.11	H.HD.04	2.94375	No	No	0	0	0
791	1x35	1x39	2.9275	No	No	0	7	6
792	6x29	6x30	2.9075	No	No	0	0	9
793	4x59	4x60	2.89906	No	No	0	8	7
794	b.1x15	b.1x19	2.89688	No	No	0	7	6
795	G.HN.43	b.b5x6	2.89406	No	No	0	9	6
796	3x56	I2x50	2.89344	No	No	0	7	8
797	b.l1x5	b.l3x1	2.89219	No	Yes	0	7	9
798	b.b10x5	b.l6x2	2.88687	Yes	No	0	9	6
799	5x66	6x31	2.88656	No	No	0	7	7
800	G.H4.08	G.HG.01	2.86312	No	No	0	5	5
801	b.l27x2	b.l2x2	2.845	No	No	0	1	1
802	b.b24x1	b.l25x5	2.83063	No	No	0	4	7
803	H.HE.08	H.HE.11	2.82812	No	No	0	0	0
804	b.l5x3	b.l5x5	2.82125	No	Yes	0	8	9
805	6x43	7x48	2.81594	No	No	0	7	6
806	b.b11x4	b.l9x7	2.80969	Yes	No	0	9	7
807	6x49	6x53	2.80719	Yes	No	0	7	7
808	G.h3s5.01	G.h3s5.02	2.805	No	No	0	3	4
809	3x27	3x31	2.80156	No	No	0	6	6
810	3x54	5x61	2.7975	No	No	0	8	9
811	6x32	G.H5.24	2.7975	No	No	0	8	7
812	6x51	7x37	2.79187	Yes	No	0	8	6
813	5x29	E3	2.79063	No	Yes	0	0	6
814	b.b5x3	b.l1x2	2.77938	Yes	No	0	9	9
815	b.b16x3	b.b19x2	2.77	No	Yes	0	6	6
816	6x45	6x46	2.7675	No	No	0	7	5
817	b.1x4	g.h1x4	2.7575	Yes	No	0	8	5
818	G.h4s6.08	G.h4s6.13	2.75469	No	No	0	7	7
819	b.b21x7	b.b25x1	2.75344	Yes	No	0	5	2
820	G.h2s4.02	G.h2s4.03	2.74938	Yes	No	0	7	6
821	b.b19x2	b.l20x1	2.7425	Yes	No	0	6	6
822	b.b20x1	b.l21x5	2.74094	No	No	0	5	4
823	4x40	4x44	2.73563	No	No	0	6	2
824	G.H5.13	I3	2.735	Yes	Yes	0	7	4
825	g.ctx7	g.ctx8	2.73438	No	No	0	4	8
826	1x50	2x51	2.70406	No	No	0	9	8
827	G.HN.52	I2x55	2.7	No	No	0	4	6
828	2x66	E1x51	2.69875	No	No	0	6	4
829	b.h2x4	g.h2x5	2.68719	No	No	0	3	6
830	1x59	8x57	2.68656	No	No	0	7	8
831	b.b28x1	b.b28x2	2.68219	No	No	0	4	4
832	G.HN.39	b.b5x5	2.68063	No	Yes	0	5	5
833	b.l24x2	g.h2x12	2.67844	Yes	No	0	6	7
834	b.b9x2	b.l12x1	2.665	No	No	0	5	6
835	b.l27x4	g.ctx4	2.66437	No	No	0	9	7
836	b.b7x1	b.b9x1	2.66375	Yes	No	0	4	4
837	G.H3.11	G.H3.15	2.65375	No	Yes	0	7	8
838	1x60	8x56	2.63312	Yes	No	0	8	6
839	6x36	6x40	2.62625	No	Yes	0	8	8
840	G.S2.07	G.S3.02	2.625	No	No	0	3	4
841	H.HC.08	H.HC.12	2.62313	No	No	0	0	0
842	H.HA.07	H.HF.04	2.6225	No	No	0	0	0
843	b.l17x5	b.l19x1	2.61906	No	No	0	6	9
844	G.H3.03	G.s4h3.14	2.61562	No	No	0	4	6
845	1x60	CT	2.61	Yes	Yes	7	8	5
846	1x53	7x54	2.58469	No	Yes	0	9	8
847	b.1x7	g.h1x8	2.57437	No	No	0	8	7
848	G.HG.03	G.HG.06	2.56969	No	No	0	5	5
849	b.1x5	b.1x9	2.5625	No	No	0	3	4
850	g.h2x14	g.h2x15	2.56219	No	No	0	4	6
851	b.b8x5	b.l8x4	2.56125	No	No	0	4	3
852	b.lhb1x3	g.h2x9	2.5525	No	No	0	2	4
853	5x62	6x37	2.55187	Yes	No	0	7	9
854	6x56	6x60	2.54562	No	No	0	7	5
855	G.H1.06	G.H1.10	2.5425	No	No	0	9	8
856	G.h2s4.01	G.h2s4.04	2.53812	Yes	No	0	9	9
857	4x39	I1x51	2.53688	No	No	0	5	7
858	b.b17x2	g.h1x13	2.52594	No	No	0	3	1
859	G.h1ha.04	H.HF.04	2.52375	Yes	No	0	0	0
860	1x54	1x58	2.52188	No	No	0	7	5
861	8x47	8x50	2.52063	No	Yes	0	9	9
862	b.lhb1x10	b.lhb1x8	2.51844	No	No	0	4	2
863	b.lhb1x11	b.lhb1x9	2.50813	No	No	0	4	3
864	4x68	E2	2.4975	No	Yes	1	4	5
865	2x39	G.H5.22	2.49188	No	No	0	8	4
866	G.hfs2.07	b.l7x4	2.49094	No	No	0	8	9
867	H.HF.02	H.HF.06	2.4825	No	No	0	0	0
868	3x42	4x49	2.47875	No	No	0	8	8
869	6x40	7x52	2.47438	Yes	No	0	8	8
870	G.H5.20	G.H5.26	2.46781	Yes	No	0	8	8
871	G.S3.02	G.hns1.03	2.46625	No	No	0	4	4
872	H.HB.02	H.hchd.01	2.44	No	Yes	0	0	0
873	5x42	5x46	2.43844	No	No	0	6	6
874	7x36	7x40	2.435	No	No	0	5	8
875	4x38	4x41	2.42188	No	No	0	8	8
876	b.b12x6	b.l9x2	2.41656	Yes	No	0	8	5
877	b.b1x1	b.lhb1x10	2.41031	No	No	0	5	4
878	G.H5.13	G.H5.17	2.40969	Yes	No	0	7	5
879	6x54	7x34	2.40938	No	No	0	6	7
880	2x61	2x65	2.40469	No	No	0	8	6
881	1x36	2x65	2.4	No	No	0	5	6
882	H.HA.26	H.hahb.06	2.39438	No	Yes	0	0	0
883	b.b13x1	b.b9x2	2.39062	No	No	0	4	5
884	b.b20x4	b.l17x2	2.39062	Yes	No	0	8	6
885	G.HN.11	G.HN.34	2.37937	No	No	0	2	3
886	G.H4.12	G.H4.16	2.37469	No	No	0	5	3
887	g.h1x12	g.h1x9	2.3625	No	No	0	6	6
888	H.HB.03	H.hahb.09	2.3625	No	No	0	0	0
889	b.b7x5	b.l9x7	2.35125	No	No	0	9	7
890	b.b24x2	b.l25x1	2.34562	No	No	0	5	3
891	2x49	4x50	2.33812	No	Yes	0	9	9
892	2x42	4x42	2.33781	Yes	No	0	8	8
893	2x67	E2	2.33344	No	Yes	1	6	5
894	G.HN.42	G.HN.45	2.33063	No	No	0	4	4
895	4x38	G.hns1.02	2.31437	No	No	0	8	4
896	H.HE.01	H.HF.06	2.30625	No	No	0	0	0
897	8x47	8x48	2.3	No	No	0	9	5
898	H.HE.04	H.HF.03	2.29875	No	No	0	0	0
899	3x40	5x50	2.29813	No	No	0	9	9
900	b.1x1	b.1x5	2.29531	No	No	0	4	3
901	5x65	6x33	2.29	No	No	0	8	9
902	6x62	E2	2.2725	No	Yes	0	0	5
903	G.HN.46	G.HN.49	2.26562	No	No	0	4	4
904	H.HB.07	H.HB.10	2.26312	No	Yes	0	0	0
905	5x68	G.H5.13	2.25312	No	Yes	0	8	7
906	b.l24x3	b.lhb1x5	2.24719	No	No	0	5	1
907	G.H3.10	G.H3.14	2.22156	No	No	0	5	8
908	b.1x2	b.ntx1	2.2075	No	No	0	1	5
909	6x43	7x52	2.20281	No	No	0	7	8
910	4x63	4x64	2.20094	No	No	0	6	7
911	1x40	1x43	2.17438	No	Yes	0	5	7
912	1x56	8x57	2.16781	No	No	0	9	8
913	5x38	5x42	2.16562	No	No	0	5	6
914	b.b18x5	b.l18x4	2.165	Yes	No	0	5	7
915	g.h1x3	g.ntx4	2.165	No	No	0	3	4
916	H.hahb.07	H.hahb.08	2.16437	No	No	0	0	0
917	3x26	4x62	2.16188	No	No	0	7	6
918	G.H1.03	G.s1h1.06	2.16125	No	No	0	9	9
919	3x37	4x56	2.15469	Yes	No	0	8	8
920	b.b27x4	b.b28x3	2.1375	No	Yes	0	5	7
921	G.hns1.03	I2x55	2.13063	No	No	0	4	6
922	H.HA.16	H.HB.12	2.13063	Yes	No	0	0	0
923	g.h1x11	g.h1x7	2.12	No	No	0	9	2
924	G.s6h5.02	G.s6h5.04	2.1125	Yes	No	0	7	9
925	5x44	6x56	2.11125	No	No	0	7	7
926	b.b26x4	b.b2x5	2.1075	No	Yes	0	5	7
927	H.HD.01	H.hahb.07	2.09125	No	No	0	0	0
928	H.HE.11	H.HF.03	2.08437	No	No	0	0	0
929	5x48	6x56	2.0775	No	No	0	7	7
930	g.l1x3	g.l1x5	2.05625	No	No	0	1	4
931	b.1x4	g.h1x8	2.04875	Yes	No	0	8	7
932	G.s3h2.01	G.s3h2.02	2.04406	No	No	0	9	9
933	b.b18x4	b.b22x4	2.0425	No	No	0	3	5
934	4x38	4x40	2.03375	No	No	0	8	6
935	G.H1.01	G.hfs2.02	2.03375	Yes	No	0	9	0
936	G.H3.07	G.H3.10	2.03281	No	No	0	5	5
937	H.HE.02	H.hdhe.03	2.02625	Yes	No	0	0	0
938	3x21	E1x50	2.02125	No	Yes	0	7	9
939	b.l22x2	b.l27x4	2.01312	No	No	0	1	9
940	5x59	5x63	2.01187	No	No	0	4	5
941	g.h1x5	g.h1x9	1.99906	No	No	0	6	6
942	b.1x4	b.ntx2	1.9875	Yes	No	0	8	5
943	H.HF.03	H.hehf.07	1.9875	No	No	0	0	0
944	E1x51	E1x52	1.97719	No	Yes	0	4	7
945	1x29	1x31	1.975	No	No	0	2	6
946	b.lhb1x4	b.lhb1x5	1.96219	No	No	0	1	1
947	1x49	7x50	1.95812	No	No	0	9	9
948	2x52	3x31	1.955	No	No	0	8	6
949	1x54	2x47	1.95156	No	No	0	7	9
950	2x41	4x42	1.95156	No	No	0	7	8
951	G.H4.02	G.HG.09	1.9375	No	No	0	3	1
952	b.b12x1	b.l13x5	1.93375	No	No	0	6	5
953	1x45	7x47	1.92906	No	No	0	5	8
954	b.b9x3	b.l5x2	1.92688	Yes	No	0	6	6
955	G.H4.07	G.HG.15	1.92313	No	No	0	7	6
956	4x60	5x39	1.92094	No	No	0	7	8
957	4x48	4x52	1.90062	No	No	0	4	5
958	5x45	5x48	1.88844	No	No	0	6	7
959	G.H4.04	G.HG.05	1.88625	No	No	0	3	5
960	2x41	4x43	1.885	No	No	0	7	5
961	1x43	1x47	1.87906	Yes	No	0	7	7
962	G.s1h1.02	G.s1h1.03	1.87688	No	No	0	8	7
963	8x50	8x54	1.87625	Yes	No	0	9	9
964	b.1x6	b.1x9	1.86656	No	No	0	3	4
965	b.b2x2	b.b6x3	1.86625	No	No	0	7	8
966	1x42	7x39	1.8625	No	Yes	0	7	8
967	6x25	G.H5.26	1.8625	No	No	0	0	8
968	1x51	2x51	1.86187	No	No	0	5	8
969	7x55	8x54	1.8275	No	No	0	7	9
970	7x24	NT	1.82	No	Yes	0	0	0
971	b.b12x7	b.b13x4	1.81063	No	No	0	9	4
972	H.HC.11	H.HD.07	1.80875	No	Yes	0	0	0
973	8x49	G.H5.24	1.80156	No	No	0	7	7
974	G.HN.46	G.HN.50	1.795	No	No	0	4	5
975	H.HD.07	H.HE.03	1.79125	Yes	No	0	0	0
976	2x62	E1x52	1.77688	No	Yes	0	7	7
977	b.b10x5	b.b6x4	1.77562	Yes	No	0	9	7
978	5x41	5x45	1.76906	No	No	0	7	6
979	b.1x11	g.h1x12	1.7625	No	No	0	8	6
980	b.l2x2	b.l6x2	1.75	No	No	0	1	6
981	G.HN.35	G.HN.38	1.745	No	No	0	4	3
982	b.1x22	g.l1x4	1.74312	No	No	0	3	8
983	G.H1.12	G.h1ha.01	1.73906	No	No	0	8	4
984	H.HE.04	H.HE.05	1.7375	No	No	0	0	0
985	b.b22x5	b.l24x1	1.73469	Yes	No	0	7	5
986	1x44	1x48	1.73063	No	No	0	5	5
987	6x22	I3	1.72375	No	Yes	0	0	4
988	1x38	7x39	1.72219	No	Yes	0	4	8
989	5x62	6x38	1.7025	Yes	No	0	7	7
990	b.b16x2	b.l17x1	1.7	No	No	0	5	2
991	4x65	4x66	1.69	No	No	0	7	5
992	G.HN.45	G.HN.49	1.68313	No	No	0	4	4
993	b.b21x5	b.h2x2	1.67594	No	No	0	4	1
994	b.b16x6	b.l13x2	1.67125	Yes	No	0	8	6
995	b.b28x6	b.l25x2	1.66875	Yes	No	0	9	5
996	b.lhb1x6	b.lhb1x7	1.6675	Yes	No	0	3	1
997	G.S2.04	G.s1h1.11	1.6625	Yes	No	0	7	0
998	H.HB.03	H.hahb.06	1.64188	No	Yes	0	0	0
999	b.1x1	b.1x4	1.6375	No	Yes	0	4	8
1000	b.1x16	b.1x17	1.63688	No	No	0	4	2
1001	G.S3.07	G.s3h2.01	1.62625	Yes	No	0	9	9
1002	G.s1h1.01	G.s1h1.05	1.62594	No	No	0	9	9
1003	b.1x8	g.h1x8	1.60687	No	No	0	5	7
1004	G.s4h3.08	G.s4h3.11	1.595	No	No	0	0	0
1005	2x55	2x551	1.5875	No	No	0	5	6
1006	6x61	7x27	1.5875	No	No	0	6	0
1007	H.HA.25	H.hdhe.01	1.585	No	No	0	0	0
1008	G.HN.45	G.HN.48	1.56562	No	No	0	4	3
1009	H.hehf.04	H.hehf.06	1.56375	Yes	No	0	0	0
1010	4x64	5x34	1.55562	No	No	0	7	0
1011	G.S3.07	G.s1h1.07	1.555	Yes	No	0	9	0
1012	1x30	1x34	1.55438	No	No	0	4	3
1013	b.b16x1	b.l17x3	1.55156	No	Yes	0	4	9
1014	b.1x12	b.1x16	1.55125	No	No	0	6	4
1015	b.1x12	g.h1x11	1.54219	No	No	0	6	9
1016	b.h2x1	g.h2x5	1.53063	No	No	0	5	6
1017	1x47	1x48	1.52437	No	No	0	7	5
1018	8x58	CT	1.5175	No	Yes	0	8	5
1019	G.HG.02	G.s6h5.02	1.5075	No	Yes	0	9	7
1020	b.1x1	g.ntx4	1.5	No	No	0	4	4
1021	H.HA.11	H.hehf.04	1.49813	No	Yes	0	0	0
1022	H.HB.01	H.hahb.08	1.49688	No	No	0	0	0
1023	G.h4s6.10	G.h4s6.12	1.49625	No	No	0	4	3
1024	H.HA.12	H.hbhc.14	1.4825	No	No	0	0	0
1025	7x54	8x51	1.47938	Yes	No	0	8	9
1026	G.H5.14	G.H5.18	1.47031	No	No	0	6	4
1027	G.H4.04	G.HG.08	1.46812	No	No	0	3	6
1028	H.HA.20	H.HA.24	1.46063	No	No	0	0	0
1029	H.HA.02	H.HA.05	1.45375	No	No	0	0	0
1030	7x40	7x43	1.45312	No	No	0	8	7
1031	G.h2s4.03	G.h3s5.02	1.4475	No	No	0	6	4
1032	G.H1.02	G.hfs2.02	1.44375	No	No	0	9	0
1033	G.H5.17	G.H5.21	1.43969	No	No	0	5	5
1034	g.h1x3	g.h1x6	1.43938	No	No	0	3	4
1035	g.ctx1	g.ctx2	1.43437	No	No	0	1	3
1036	G.HN.11	G.HN.37	1.43281	No	No	0	2	3
1037	5x37	6x59	1.42437	No	No	0	5	8
1038	8x52	8x53	1.415	No	No	0	6	8
1039	G.H1.09	G.h1ha.04	1.415	No	Yes	0	7	0
1040	G.H1.10	H.HF.01	1.3725	No	No	0	8	0
1041	H.HA.29	H.HD.09	1.36688	No	No	0	0	0
1042	7x28	NT	1.36312	No	Yes	0	0	0
1043	b.1x2	b.ntx3	1.3625	No	No	0	1	0
1044	1x28	1x30	1.36125	No	No	0	0	4
1045	5x75	G.H5.13	1.3575	No	Yes	0	4	7
1046	H.HE.11	H.hehf.04	1.35063	No	Yes	0	0	0
1047	g.h1x6	g.h1x9	1.35	No	No	0	4	6
1048	H.HE.12	H.hehf.04	1.34125	No	Yes	0	0	0
1049	H.HA.27	H.HB.10	1.34063	No	Yes	0	0	0
1050	b.1x18	b.b21x1	1.34	No	Yes	0	4	7
1051	H.HF.02	H.HF.05	1.33	No	No	0	0	0
1052	b.b24x5	b.b25x5	1.3225	Yes	No	0	5	4
1053	5x71	I3	1.31906	No	Yes	0	5	4
1054	3x41	4x52	1.2925	No	No	0	7	5
1055	H.HA.16	H.HC.03	1.28937	Yes	No	0	0	0
1056	H.HB.02	H.HC.10	1.28813	No	No	0	0	0
1057	7x23	7x26	1.28813	No	No	0	0	0
1058	G.H1.07	G.H1.11	1.28469	No	No	0	9	8
1059	g.ntx1	g.ntx2	1.27781	No	No	0	4	3
1060	g.ctx2	g.h2x15	1.26875	No	No	0	3	6
1061	G.HN.36	b.b5x2	1.2675	No	Yes	0	4	7
1062	5x68	5x72	1.26625	No	No	0	8	4
1063	b.1x12	b.b21x1	1.26562	No	Yes	0	6	7
1064	H.HA.13	H.HB.14	1.25312	Yes	No	0	0	0
1065	1x54	2x48	1.25281	No	No	0	7	6
1066	G.H4.10	G.H4.13	1.24	No	No	0	7	2
1067	H.HE.01	H.hdhe.04	1.2225	No	No	0	0	0
1068	b.b24x5	b.b25x4	1.21938	Yes	No	0	5	4
1069	G.S5.05	G.s1h1.10	1.20625	Yes	No	0	9	0
1070	6x28	I3	1.20375	No	Yes	0	0	4
1071	b.b1x3	g.ctx17	1.19969	Yes	No	0	7	7
1072	b.lhb1x3	g.h2x13	1.15406	No	No	0	2	1
1073	H.HA.19	H.HC.10	1.14875	No	No	0	0	0
1074	H.HC.04	H.hbhc.14	1.14688	No	No	0	0	0
1075	3x37	5x42	1.13625	Yes	No	0	8	6
1076	g.h2x13	g.h2x16	1.1325	No	No	0	1	4
1077	g.ctx1	g.ctx7	1.125	No	No	0	1	4
1078	b.1x15	g.h1x15	1.11687	No	No	0	7	8
1079	b.1x22	g.l1x6	1.11063	No	No	0	3	4
1080	H.HD.01	H.hchd.01	1.10687	No	Yes	0	0	0
1081	H.HA.01	H.hehf.05	1.10312	No	No	0	0	0
1082	5x33	5x37	1.1	No	No	0	0	5
1083	H.HA.08	H.hehf.06	1.09375	No	No	0	0	0
1084	H.HA.22	H.HD.03	1.09375	No	No	0	0	0
1085	G.hfs2.02	H.hdhe.04	1.0825	No	No	0	0	0
1086	G.s4h3.10	G.s4h3.11	1.07812	No	No	0	0	0
1087	H.hahb.06	H.hchd.01	1.07812	Yes	Yes	0	0	0
1088	7x32	7x36	1.0775	No	No	0	4	5
1089	G.h1ha.05	H.HA.02	1.0775	No	No	0	0	0
1090	G.S2.06	G.s1h1.15	1.06875	Yes	No	0	8	0
1091	7x26	E3	1.06125	No	Yes	0	0	6
1092	H.HA.23	H.hahb.06	1.05813	No	Yes	0	0	0
1093	b.1x14	b.1x18	1.05375	No	No	0	4	4
1094	6x27	6x28	1.0525	No	No	0	0	0
1095	H.HB.05	H.HC.09	1.04625	No	No	0	0	0
1096	4x54	4x58	1.04	No	No	0	6	6
1097	G.H1.01	H.hdhe.05	1.0375	Yes	No	0	9	0
1098	b.1x10	b.1x6	1.03375	No	No	0	1	3
1099	H.HA.16	H.HC.07	1.02062	Yes	No	0	0	0
1100	H.HA.23	H.HB.10	1.0175	No	Yes	0	0	0
1101	G.s4h3.07	G.s4h3.15	1.01719	No	No	0	4	9
1102	H.HA.26	H.HD.06	1.01312	No	No	0	0	0
1103	G.H2.01	b.l9x4	1.01031	No	No	0	9	5
1104	H.HD.06	H.hdhe.01	1.00875	No	No	0	0	0
1105	G.h1ha.04	H.HA.03	1.00625	Yes	No	0	0	0
1106	G.hfs2.01	H.HA.07	0.9825	No	No	0	0	0
1107	H.HA.16	H.hbhc.03	0.9825	Yes	No	0	0	0
1108	G.s4h3.09	G.s4h3.10	0.98125	No	No	0	0	0
1109	G.HN.32	G.HN.33	0.975	No	Yes	0	5	4
1110	5x70	6x31	0.970625	No	No	0	7	7
1111	H.HA.04	H.hehf.05	0.969375	No	No	0	0	0
1112	G.H5.03	G.s1h1.14	0.964375	Yes	No	0	8	0
1113	H.HD.03	H.hchd.01	0.9625	No	Yes	0	0	0
1114	1x31	7x35	0.959375	No	No	0	6	6
1115	H.HB.13	H.hbhc.02	0.950625	No	No	0	0	0
1116	H.HD.07	H.HE.02	0.93625	Yes	Yes	0	0	0
1117	5x28	E2	0.93625	No	Yes	1	0	5
1118	G.s4h3.12	G.s4h3.14	0.934375	No	No	0	4	6
1119	H.HB.02	H.HC.09	0.93125	No	No	0	0	0
1120	H.hehf.05	H.hehf.06	0.924375	No	No	0	0	0
1121	G.h1ha.05	H.HA.03	0.92	No	No	0	0	0
1122	4x51	4x54	0.911875	No	No	0	4	6
1123	G.H1.06	G.h1ha.04	0.895	No	Yes	0	9	0
1124	1x41	1x45	0.889063	No	No	0	5	5
1125	g.l1x1	g.l1x2	0.885	No	No	0	1	2
1126	7x51	7x55	0.875312	No	No	0	6	7
1127	H.HA.16	H.hbhc.14	0.87125	Yes	No	0	0	0
1128	H.HA.12	H.hehf.04	0.86875	No	Yes	0	0	0
1129	5x73	G.S6.02	0.86875	No	Yes	0	4	8
1130	G.H5.01	G.s1h1.17	0.855	No	No	0	9	0
1131	G.S5.07	G.s1h1.06	0.85	Yes	No	0	9	9
1132	H.HA.18	H.HE.02	0.84	No	Yes	0	0	0
1133	5x55	5x59	0.839375	No	No	0	5	4
1134	5x69	6x30	0.835	No	No	0	5	9
1135	g.ctx11	g.ctx17	0.822187	No	No	0	4	7
1136	H.HA.23	H.HB.06	0.811875	No	No	0	0	0
1137	G.HN.09	G.HN.34	0.8075	Yes	No	0	5	3
1138	H.HA.29	H.hahb.04	0.8025	No	No	0	0	0
1139	H.HE.02	H.hdhe.04	0.8	Yes	No	0	0	0
1140	5x31	5x34	0.7975	No	No	0	0	0
1141	G.s1h1.04	H.hdhe.02	0.79625	No	No	0	9	0
1142	G.HN.38	G.HN.39	0.783125	No	No	0	3	5
1143	g.ntx1	g.ntx3	0.7825	No	No	0	4	4
1144	1x36	1x37	0.7775	No	No	0	5	4
1145	7x23	7x25	0.775625	No	No	0	0	0
1146	G.HN.53	G.hns1.03	0.775	No	No	0	1	4
1147	G.H1.07	G.s6h5.03	0.75875	No	No	0	9	9
1148	G.hfs2.03	H.HA.10	0.745	No	No	0	0	0
1149	H.HC.04	H.HE.13	0.741875	No	No	0	0	0
1150	G.hfs2.01	H.HA.14	0.74	No	No	0	0	0
1151	H.HA.24	H.HB.10	0.733125	No	Yes	0	0	0
1152	G.HN.51	G.hns1.01	0.73125	No	No	0	5	3
1153	H.HA.26	H.hahb.04	0.72875	No	No	0	0	0
1154	7x26	7x29	0.7275	No	No	0	0	0
1155	H.HA.13	H.hbhc.01	0.716875	Yes	No	0	0	0
1156	H.HA.15	H.HE.09	0.713125	No	Yes	0	0	0
1157	G.S3.01	G.s2s3.02	0.708438	No	No	0	4	4
1158	6x32	6x35	0.699687	No	No	0	8	7
1159	1x29	1x33	0.695625	No	No	0	2	5
1160	H.HA.17	H.HB.14	0.69375	No	No	0	0	0
1161	3x23	3x27	0.6925	No	No	0	4	6
1162	g.h1x2	g.h1x5	0.69125	No	No	0	2	6
1163	G.s1h1.13	G.s1h1.17	0.68625	No	No	0	0	0
1164	6x25	6x26	0.6775	No	No	0	0	0
1165	G.hfs2.03	G.hfs2.04	0.6625	No	No	0	0	0
1166	6x38	6x42	0.66125	No	No	0	7	7
1167	G.H1.09	G.h1ha.02	0.65875	No	No	0	7	0
1168	G.S2.08	G.s1h1.18	0.643125	No	No	0	5	0
1169	H.hahb.04	H.hahb.05	0.635625	No	No	0	0	0
1170	G.HN.31	G.HN.32	0.63375	No	No	0	1	5
1171	H.HD.02	H.hchd.01	0.628125	No	Yes	0	0	0
1172	4x47	4x48	0.61125	No	No	0	4	4
1173	b.1x4	b.ntx4	0.6075	Yes	No	0	8	0
1174	H.HE.06	H.HE.09	0.605625	No	Yes	0	0	0
1175	6x23	I3	0.60125	No	Yes	0	0	4
1176	H.HC.02	H.hbhc.15	0.58875	No	No	0	0	0
1177	H.HA.09	H.hbhc.04	0.57375	No	No	0	0	0
1178	5x52	5x56	0.540625	No	No	0	5	5
1179	G.H2.01	G.hfs2.04	0.54	No	No	0	9	0
1180	H.HA.13	H.hbhc.03	0.5375	Yes	No	0	0	0
1181	H.HA.20	H.HB.09	0.5375	No	No	0	0	0
1182	H.HC.02	H.HC.03	0.52125	No	No	0	0	0
1183	H.HA.09	H.HA.13	0.50875	No	Yes	0	0	0
1184	1x60	8x60	0.49625	Yes	No	0	8	5
1185	5x32	5x34	0.469687	No	No	0	0	0
1186	G.h1ha.02	G.h1ha.03	0.46375	No	No	0	0	0
1187	4x68	4x69	0.46	No	No	0	4	4
1188	H.HD.08	H.HD.10	0.44625	No	No	0	0	0
1189	6x63	E3	0.44625	No	Yes	0	0	6
1190	G.h4s6.09	G.h4s6.11	0.445	No	No	0	4	1
1191	5x28	5x30	0.445	No	No	0	0	0
1192	H.HD.05	H.HD.09	0.436875	No	No	0	0	0
1193	H.HB.07	H.HB.11	0.3975	No	No	0	0	0
1194	5x75	G.H5.09	0.395	No	No	0	4	4
1195	4x51	4x55	0.394375	No	No	0	4	5
1196	g.h1x1	g.ntx8	0.3875	No	No	0	2	0
1197	b.l8x6	b.l8x9	0.375	No	No	0	4	3
1198	4x67	4x68	0.3725	No	No	0	4	4
1199	g.ntx1	g.ntx4	0.3725	No	No	0	4	4
1200	H.HC.08	H.HE.09	0.3525	No	Yes	0	0	0
1201	H.HC.01	H.HC.02	0.305625	No	No	0	0	0
1202	H.hehf.01	H.hehf.02	0.301875	No	No	0	0	0
1203	G.s1h1.09	G.s1h1.12	0.28125	No	No	0	0	0
1204	H.HB.05	H.HC.06	0.274375	No	No	0	0	0
1205	G.s1h1.12	G.s1h1.16	0.2725	No	No	0	0	0
1206	b.l24x2	b.lhb1x1	0.2575	Yes	No	0	6	1
1207	b.1x21	g.l1x6	0.252813	No	No	0	3	4
1208	G.HN.06	G.HN.09	0.23	No	Yes	0	0	5
1209	G.hfs2.05	G.s3h2.02	0.2275	No	No	0	0	9
1210	G.HN.09	G.HN.10	0.21125	Yes	No	0	5	4
1211	b.l21x3	b.l21x4	0.210938	No	No	0	3	4
1212	G.s1h1.18	G.s1h1.19	0.19875	No	No	0	0	0
1213	H.HA.21	H.hdhe.03	0.1975	No	No	0	0	0
1214	g.h2x6	g.h2x7	0.1925	No	No	0	2	5
1215	H.HA.28	H.HA.29	0.18375	No	No	0	0	0
1216	H.HC.04	H.HC.05	0.1825	No	No	0	0	0
1217	8x55	8x59	0.17625	No	No	0	6	5
1218	G.s1h1.13	G.s1h1.16	0.17125	No	No	0	0	0
1219	H.HE.09	H.HE.10	0.17	Yes	No	0	0	0
1220	G.hgh4.06	G.hgh4.07	0.157187	No	No	0	2	8
1221	G.HN.05	G.HN.09	0.127188	No	Yes	0	0	5
1222	G.HN.29	G.HN.33	0.127188	No	Yes	0	0	4
1223	G.s1h1.19	G.s1h1.20	0.11625	No	No	0	0	0
1224	b.l21x6	b.l21x7	0.1025	No	No	0	3	5
1225	5x74	I3	0.095625	No	Yes	0	4	4
1226	H.hbhc.05	H.hbhc.15	0.094375	No	No	0	0	0
1227	H.HB.08	H.HB.11	0.083125	No	No	0	0	0
1228	H.HE.10	H.hehf.01	0.083125	No	No	0	0	0
1229	6x23	6x24	0.0534375	No	No	0	0	0
1230	b.1x20	b.lh12x1	0.0503125	No	No	0	2	3
1231	G.HN.06	G.HN.08	0.045	No	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	b.1x4	1.80775	5	0	8
2	b.lhb1x6	4.29109	4	8	3
3	b.b1x3	4.09984	4	3	7
4	b.b1x6	8.67976	4	3	9
5	b.l1x3	9.13	5	3	9
6	b.b2x1	6.76438	5	2	8
7	b.b2x5	5.60359	6	0	7
8	b.b3x3	3.90744	5	13	8
9	b.l3x1	6.07672	4	2	9
10	b.l3x2	6.12523	4	3	9
11	b.b4x3	4.44664	4	0	7
12	b.b4x6	9.98203	6	3	9
13	b.b5x2	6.07914	4	0	7
14	b.b5x3	7.00769	5	3	9
15	b.b5x5	5.21648	4	0	5
16	b.b5x7	6.15242	4	0	7
17	b.l5x1	4.38664	4	0	8
18	b.l5x5	5.88323	9	2	9
19	b.b6x5	4.11538	5	13	6
20	b.b7x1	5.12556	5	0	4
21	b.l7x2	4.67922	4	2	9
22	b.b8x4	5.62725	5	0	6
23	b.l8x1	3.98336	4	13	5
24	b.b9x3	3.26023	4	0	6
25	b.l9x3	8.5768	4	2	9
26	b.l9x6	4.95824	8	2	8
27	b.b10x5	4.37406	6	0	9
28	b.b11x4	5.42687	4	2	9
29	b.b11x5	4.12023	4	4	6
30	b.l11x2	8.22727	4	2	9
31	b.b12x3	3.69113	5	4	8
32	b.b12x6	8.2249	6	2	8
33	b.b13x7	8.35313	5	4	7
34	b.l13x3	7.23844	6	4	9
35	b.l13x6	4.03365	6	2	9
36	b.b14x3	4.5357	4	4	5
37	b.b15x1	7.26669	5	4	9
38	b.l15x2	5.86269	5	4	9
39	b.b16x4	10.6498	4	4	6
40	b.b16x6	7.96375	6	4	8
41	b.b16x7	7.11391	4	0	9
42	b.b17x7	8.20836	4	5	8
43	b.l17x3	8.66557	6	5	9
44	b.l17x6	7.71477	4	2	9
45	b.b18x3	5.40648	4	5	8
46	b.b18x5	4.60619	5	5	5
47	b.l18x1	6.49933	7	9	6
48	b.l18x2	5.77812	4	9	7
49	b.b19x2	6.42616	7	5	6
50	b.b19x4	6.19945	4	5	8
51	b.l19x2	6.72375	5	5	9
52	b.b20x2	4.76219	4	5	6
53	b.b20x4	7.98302	6	5	8
54	b.b20x6	7.53744	5	5	6
55	b.b21x1	6.00734	6	5	7
56	b.b21x7	5.77151	6	0	5
57	b.l21x2	6.43781	4	0	4
58	b.b22x5	4.9515	5	9	7
59	b.l22x5	6.36225	5	8	9
60	b.b23x2	4.7357	4	9	6
61	b.b23x6	6.77615	6	7	7
62	b.l23x1	7.95305	4	0	6
63	b.l23x2	5.64961	4	7	8
64	b.b24x4	7.27617	4	7	6
65	b.b24x5	2.42812	4	0	5
66	b.b24x6	7.19906	4	7	8
67	b.b24x7	7.32992	4	8	9
68	b.l24x2	3.50867	4	0	6
69	b.l25x3	8.87331	5	11	9
70	b.l28x1	10.8947	7	2	9
71	b.l28x2	8.07398	4	11	9
72	b.b28x3	4.41363	5	3	7
73	b.b28x4	8.20023	4	11	6
74	b.b28x6	8.13325	5	11	9
75	g.h2x11	9.35273	4	9	6
76	g.ctx3	6.81019	5	8	9
77	g.ctx14	5.56922	4	3	9
78	g.ctx15	6.53891	4	3	9
79	g.ctx16	4.79917	9	3	8
80	1x43	3.20438	4	0	7
81	1x60	3.32344	6	7	8
82	2x42	5.06255	6	0	8
83	2x50	6.18469	5	1	9
84	2x57	4.24859	4	1	8
85	2x60	4.75781	5	1	7
86	E1x50	7.32828	6	1	9
87	E1x52	4.75044	5	0	7
88	3x28	5.46164	4	0	7
89	3x37	3.59058	7	1	8
90	3x43	4.18975	5	1	8
91	3x50	6.10725	5	1	9
92	4x50	5.09594	4	15	9
93	E2	13.6976	17	1	5
94	E2x52	5.63258	4	1	7
95	5x47	7.41956	5	1	9
96	5x58	5.5775	5	0	9
97	5x62	3.46789	4	0	7
98	I3	1.27974	6	0	4
99	6x40	3.53844	4	0	8
100	6x44	5.11023	4	1	9
101	6x48	5.8852	8	1	8
102	6x49	3.51539	4	0	7
103	6x51	5.57613	5	1	8
104	6x52	6.9768	4	1	8
105	E3	3.52496	7	1	6
106	7x38	5.03525	5	1	7
107	7x39	4.57419	5	1	8
108	7x42	5.54438	7	1	8
109	7x49	6.65383	4	1	9
110	7x53	5.23695	4	1	9
111	7x54	2.52898	4	0	8
112	8x50	3.1075	7	7	9
113	CT	3.652	5	7	5
114	Lig	7.23823	23	1	0
115	G.HN.09	0.343984	4	0	5
116	G.HN.33	2.44508	4	0	4
117	G.S1.04	3.81375	4	10	6
118	G.H1.01	3.84219	4	10	9
119	G.H1.04	4.77193	6	6	7
120	G.S2.04	6.98594	4	10	7
121	G.S2.06	3.64943	6	0	8
122	G.S3.03	4.82477	4	0	7
123	G.S3.04	7.84695	4	0	7
124	G.S3.05	4.36367	4	10	7
125	G.S3.07	4.06615	6	10	9
126	G.s3h2.03	5.19725	5	2	9
127	G.H2.02	4.21445	4	2	8
128	G.H2.04	3.80266	4	2	9
129	G.H2.06	6.20219	5	2	9
130	G.H2.07	5.43094	7	2	9
131	G.H2.09	4.80711	4	2	8
132	G.H2.10	3.75281	4	2	7
133	G.h2s4.01	5.80788	5	2	9
134	G.h2s4.02	3.90703	4	2	7
135	G.s4h3.03	6.741	5	16	7
136	G.s4h3.04	5.48406	6	12	8
137	G.H3.01	8.01258	4	16	9
138	G.H3.06	5.60086	4	0	7
139	G.H3.09	7.50094	4	0	9
140	G.H3.12	3.90398	4	2	7
141	G.H3.15	3.61854	6	2	8
142	G.H3.18	5.64156	4	2	9
143	G.S5.05	3.58042	6	6	9
144	G.S5.07	3.97106	5	6	9
145	G.HG.07	5.50516	4	12	9
146	G.hgh4.02	4.50367	4	0	8
147	G.S6.02	5.22897	7	17	8
148	G.S6.04	6.14453	4	6	9
149	G.s6h5.01	4.80661	6	6	9
150	G.s6h5.02	2.84844	4	0	7
151	G.s6h5.05	4.55619	5	6	9
152	G.H5.03	4.1962	6	6	8
153	G.H5.13	3.60481	5	0	7
154	G.H5.20	3.283	5	0	8
155	G.H5.23	5.82453	4	0	4
156	NT	3.9175	6	1	0
157	G.h1ha.04	1.46	4	0	0
158	H.HA.13	0.754063	4	0	0
159	H.HA.16	1.25888	5	0	0
160	H.hahb.06	1.54313	4	0	0
161	H.HB.10	1.33859	4	0	0
162	H.hchd.01	1.24312	5	0	0
163	H.HD.07	1.90562	4	0	0
164	H.HE.02	1.15062	4	0	0
165	H.HE.09	0.460312	4	0	0
166	H.hehf.04	1.3245	5	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.1x12	b.b21x1	10.0357	1.26562	No	Yes	0	6	7
2	b.b17x7	b.b21x1	15.3094	4.40469	Yes	Yes	5	8	7
3	b.b17x7	b.b20x6	15.8656	11.6216	Yes	Yes	5	8	6
4	b.b19x4	b.l17x3	10.9912	7.2325	Yes	Yes	5	8	9
5	b.l17x3	b.l19x2	19.4104	3.74062	Yes	Yes	5	9	9
6	b.l17x5	b.l19x2	28.0205	7.22344	No	Yes	0	6	9
7	b.l17x5	b.l19x1	28.1121	2.61906	No	No	0	6	9
8	b.l17x6	b.l19x1	25.2777	7.19375	Yes	No	0	9	9
9	b.l15x1	b.l17x6	22.4163	7.78	No	Yes	2	7	9
10	b.l13x6	b.l15x1	22.6031	3.64813	Yes	No	2	9	7
11	G.H2.07	b.l13x6	25.1194	4.1875	Yes	Yes	2	9	9
12	b.l5x5	b.l7x2	12.802	6.30281	Yes	Yes	2	9	9
13	b.b2x1	b.l28x1	24.6368	7.38781	Yes	Yes	2	8	9
14	b.l25x6	b.l28x1	28.6079	23.8962	No	Yes	0	8	9
15	b.l23x1	b.l25x6	28.3533	18.2766	Yes	No	0	6	8
16	b.l21x7	b.l23x1	27.589	5.98	No	Yes	0	5	6
17	b.l21x7	b.l23x2	27.0792	5.7375	No	Yes	0	5	8
18	b.b23x6	b.l23x2	17.0458	3.80906	Yes	Yes	7	7	8
19	b.b23x6	b.b24x6	13.9517	6.54156	Yes	Yes	7	7	8
20	b.b21x7	b.b24x6	12.9322	12.8713	Yes	Yes	0	5	8
21	b.b20x4	b.b20x6	15.4937	3.51	Yes	Yes	5	8	6
22	b.b26x1	b.l28x1	42.1469	4.36156	No	Yes	0	9	9
23	b.b26x1	b.b26x2	41.8947	3.44	No	No	0	9	7
24	b.b26x2	b.b2x3	41.6425	6.02469	No	No	0	7	6
25	b.b2x3	b.b2x5	41.3902	3.05125	No	Yes	0	6	7
26	b.b2x5	b.l27x1	19.2417	10.1597	Yes	No	0	7	7
27	b.l27x1	b.l27x3	18.7286	5.33313	No	No	14	7	7
28	b.l27x3	b.l27x5	18.4768	8.40438	No	No	0	7	5
29	b.l27x5	g.ctx4	18.4036	4.82156	No	No	0	5	7
30	g.ctx3	g.ctx4	17.6293	4.57844	Yes	No	0	9	7
31	b.b2x5	b.l4x1	10.703	5.90625	Yes	No	0	7	5
32	b.l4x1	g.ctx16	10.4486	4.00156	No	Yes	0	5	8
33	b.b2x5	b.b3x2	10.8234	8.50688	Yes	No	0	7	5
34	b.b3x2	b.b4x6	10.5657	3.95156	No	Yes	0	5	9
35	G.H3.17	G.h2s4.02	15.6692	6.33594	No	Yes	0	5	7
36	G.H2.08	G.H3.17	31.1399	4.40625	No	No	0	8	5
37	G.H2.08	G.H3.15	31.1476	3.92875	No	Yes	2	8	8
38	G.H2.04	G.H2.07	29.169	5	Yes	Yes	2	9	9
39	G.H2.09	G.H2.10	15.4348	3.04031	Yes	Yes	2	8	7
40	G.H2.10	G.h2s4.01	30.9893	3.44938	Yes	Yes	2	7	9
41	G.H2.09	G.H3.17	15.4271	6.08469	Yes	No	0	8	5
42	b.b11x6	b.l11x1	13.8452	3.53656	No	No	2	9	9
43	b.b11x6	b.l9x3	12.7681	16.0859	No	Yes	2	9	9
44	b.b11x4	b.l9x3	11.8937	6.165	Yes	Yes	2	9	9
45	b.b11x4	b.b8x1	11.5267	3.22156	Yes	No	0	9	8
46	b.b10x3	b.b8x1	11.4129	3.46938	No	No	0	8	8
47	b.l5x3	b.l5x5	10.0324	2.82125	No	Yes	0	8	9
48	6x48	Lig	40.7029	5.51937	Yes	Yes	1	8	0
49	6x44	6x48	49.7823	6.73344	Yes	Yes	1	9	8
50	3x43	6x44	58.8878	3.24437	Yes	Yes	1	8	9
51	3x43	7x53	72.9201	5.11688	Yes	Yes	1	8	9
52	3x46	7x53	37.884	4.3375	No	Yes	1	9	9
53	2x42	3x46	38.0746	3.56125	Yes	No	0	8	9
54	2x42	3x49	43.5387	11.1322	Yes	No	0	8	9
55	3x49	I2x57	89.9835	6.19625	No	No	0	9	8
56	I2x53	I2x57	90.3286	6.50094	No	No	0	9	8
57	3x52	I2x53	90.5012	3.77781	No	No	0	7	9
58	3x52	I2x52	90.6736	4.265	No	No	0	7	7
59	I2x52	I2x56	90.846	4.59969	No	No	0	7	6
60	I2x54	I2x56	91.8796	3.5175	No	No	0	7	6
61	G.S1.02	I2x54	92.0517	4.09938	No	No	0	5	7
62	G.S1.02	G.S3.03	92.3957	6.16656	No	Yes	0	5	7
63	G.S1.04	G.S3.03	93.0833	3.57656	Yes	Yes	0	6	7
64	G.S1.04	G.S3.05	24.4483	3.53594	Yes	Yes	10	6	7
65	G.S2.06	G.S3.05	28.222	5.36625	Yes	Yes	0	8	7
66	G.H1.08	G.S2.06	29.2918	4.23812	No	Yes	0	9	8
67	G.H1.08	G.H5.03	29.0984	3.06656	No	Yes	6	9	8
68	G.H5.03	G.s6h5.05	52.2423	7.025	Yes	Yes	6	8	9
69	G.s6h5.02	G.s6h5.05	100	4.13406	Yes	Yes	0	7	9
70	G.HG.01	G.s6h5.02	99.9755	3.63969	No	Yes	0	5	7
71	G.H4.08	G.HG.01	99.9672	2.86312	No	No	0	5	5
72	G.H4.08	G.S6.05	99.9421	12.4263	No	No	0	5	5
73	G.S5.06	G.S6.05	99.9081	7.04281	No	No	0	8	5
74	G.S5.04	G.S5.06	98.6573	3.76156	No	No	0	8	8
75	G.H3.09	G.S5.04	98.6467	4.07125	Yes	No	0	9	8
76	G.H3.09	G.S4.04	99.4124	14.1994	Yes	No	0	9	9
77	G.H3.12	G.S4.04	60.4476	4.39656	Yes	No	2	7	9
78	G.H2.04	G.H3.12	29.141	3.13156	Yes	Yes	2	9	7
79	3x50	7x53	37.9352	5.85625	Yes	Yes	1	9	9
80	3x50	G.H5.23	45.3844	10.7053	Yes	Yes	0	9	4
81	3x49	G.H5.23	46.2765	4.55406	No	Yes	0	9	4
82	G.S1.04	G.S4.01	68.9296	4.08063	Yes	No	0	6	8
83	G.S4.01	G.S5.03	69.0497	6.19	No	No	0	8	8
84	G.S5.03	G.S5.05	68.9804	3.49375	No	Yes	0	8	9
85	G.H5.03	G.S5.05	23.0332	3.36125	Yes	Yes	6	8	9
86	G.S5.05	G.S6.04	23.0438	3.18125	Yes	Yes	6	9	9
87	G.S6.04	G.s6h5.05	24.2151	3.66188	Yes	Yes	6	9	9
88	G.S5.05	G.s6h5.01	23.0642	3.80875	Yes	Yes	6	9	9
89	G.s6h5.01	G.s6h5.05	23.6385	4.02187	Yes	Yes	6	9	9
90	G.S1.05	G.S1.07	38.9254	5.27781	No	No	0	9	9
91	G.S1.05	G.h2s4.01	38.9104	10.8106	No	Yes	0	9	9
92	G.h2s4.02	b.l28x1	15.3945	3.16781	Yes	Yes	2	7	9
93	G.H2.09	b.l28x1	30.65	4.76281	Yes	Yes	2	8	9
94	G.H2.10	b.b2x1	15.4095	3.99	Yes	Yes	2	7	8
95	G.S1.07	G.S4.04	38.9523	4.64375	No	No	2	9	9
96	G.H3.12	G.H3.15	31.3005	3.62875	Yes	Yes	2	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x56	3x32	8.70062	1	No	No	8	9	2	1
2x56	7x42	3.75281	1	No	Yes	8	8	2	1
2x57	7x39	3.35	1	Yes	Yes	8	8	2	2
2x57	7x42	6.8425	1	Yes	Yes	8	8	2	1
2x60	2x64	3.68313	1	Yes	No	7	7	1	2
2x60	3x28	4.27625	1	Yes	Yes	7	7	1	2
2x60	7x38	5.68531	1	Yes	Yes	7	7	1	1
2x60	7x42	5.55406	1	Yes	Yes	7	8	1	1
2x63	E1x50	8.63	1	No	Yes	7	9	1	2
E1x49	E2	4.21781	0	No	Yes	5	5	2	1
3x28	E1x50	3.58938	0	Yes	Yes	7	9	2	2
3x22	E2	13.5756	1	No	Yes	4	5	2	1
3x32	7x42	6.82562	1	No	Yes	9	8	1	1
3x32	Lig	7.34875	1	No	Yes	9	0	1	0
3x33	4x57	10.2838	1	No	No	8	8	1	2
3x33	4x61	3.15188	1	No	No	8	7	1	2
3x33	Lig	9.68906	1	No	Yes	8	0	1	0
3x36	6x48	4.34125	1	No	Yes	8	8	1	1
3x36	Lig	8.56906	1	No	Yes	8	0	1	0
3x37	3x41	4.52094	1	Yes	No	8	7	1	2
3x37	4x53	3.84969	1	Yes	No	8	8	1	2
3x37	4x57	4.71062	1	Yes	No	8	8	1	2
3x37	5x461	4.30062	1	Yes	No	8	8	1	2
3x37	Lig	4.46125	1	Yes	Yes	8	0	1	0
3x40	6x48	6.61219	0	No	Yes	9	8	2	1
4x57	5x43	3.29719	0	No	No	8	8	2	1
4x61	E2x52	4.12531	0	No	Yes	7	7	2	1
4x64	E2	9.73344	1	No	Yes	7	5	2	1
E2	E2	62.7838	1	Yes	Yes	5	5	1	1
E2	E2x51	12.5359	1	Yes	No	5	4	1	2
E2	E2x52	9.43875	1	Yes	Yes	5	7	1	1
5x36	E2	8.47	0	No	Yes	7	5	2	1
5x39	E2	4.45187	1	No	Yes	8	5	2	1
5x39	5x43	4.17438	1	No	No	8	8	2	1
5x47	6x48	3.24625	1	Yes	Yes	9	8	2	1
5x47	6x52	16.4625	1	Yes	Yes	9	8	2	1
6x44	6x48	6.73344	1	Yes	Yes	9	8	2	1
6x48	6x52	3.39094	1	Yes	Yes	8	8	1	1
6x48	7x41	8.45875	1	Yes	No	8	8	1	2
6x48	7x45	8.77938	1	Yes	No	8	9	1	2
6x48	Lig	5.51937	1	Yes	Yes	8	0	1	0
6x51	6x52	4.67281	1	Yes	Yes	8	8	1	1
6x51	6x55	3.79844	1	Yes	No	8	8	1	1
6x51	7x38	4.50063	1	Yes	Yes	8	7	1	1
6x51	Lig	12.1169	1	Yes	Yes	8	0	1	0
6x52	Lig	3.38094	1	Yes	Yes	8	0	1	0
6x61	E3	6.19	0	No	Yes	6	6	2	1
7x34	7x38	3.43062	1	No	Yes	7	7	1	1
7x38	7x42	4.14094	1	Yes	Yes	7	8	1	1
7x38	Lig	7.41875	1	Yes	Yes	7	0	1	0
7x39	7x42	6.45875	1	Yes	Yes	8	8	2	1
7x42	Lig	5.23594	1	Yes	Yes	8	0	1	0
E2	E3	6.2325	1	Yes	Yes	5	6	1	1
5x40	6x55	5.16031	0	No	No	7	8	2	1
6x57	E3	3.14031	0	No	Yes	6	6	2	1
6x58	7x30	3.115	1	No	No	5	6	1	2
2x63	Lig	3.11812	1	No	Yes	7	0	1	0
4x65	E2x52	3.90875	0	No	Yes	7	7	2	1
E2	Lig	16.8766	1	Yes	Yes	5	0	1	0
E2x52	Lig	5.0575	1	Yes	Yes	7	0	1	0
5x35	E2	3.8625	0	No	Yes	0	5	2	1
6x55	Lig	4.12063	1	No	Yes	8	0	1	0
6x58	Lig	5.63688	1	No	Yes	5	0	1	0
E3	Lig	4.81375	1	Yes	Yes	6	0	1	0
7x34	Lig	5.61219	1	No	Yes	7	0	1	0
2x60	Lig	4.59031	1	Yes	Yes	7	0	1	0
5x43	Lig	3.92594	1	No	Yes	8	0	1	0
E2	NT	9.8575	1	Yes	Yes	5	0	1	1
NT	NT	3.69062	1	Yes	Yes	0	0	1	1
Lig	NT	3.08313	1	Yes	Yes	0	0	0	1
E1	Lig	4.59562	0	No	Yes	0	0	1	0
7x31	Lig	6.5975	0	No	Yes	3	0	1	0
6x51	7x37	2.79187	1	Yes	No	8	6	1	2
5x29	E3	2.79063	0	No	Yes	0	6	2	1
4x68	E2	2.4975	1	No	Yes	4	5	2	1
6x54	7x34	2.40938	0	No	No	6	7	2	1
2x67	E2	2.33344	1	No	Yes	6	5	2	1
6x62	E2	2.2725	0	No	Yes	0	5	2	1
3x37	4x56	2.15469	1	Yes	No	8	8	1	2
7x24	NT	1.82	0	No	Yes	0	0	2	1
7x28	NT	1.36312	0	No	Yes	0	0	2	1
3x37	5x42	1.13625	1	Yes	No	8	6	1	2
7x26	E3	1.06125	0	No	Yes	0	6	2	1
5x28	E2	0.93625	1	No	Yes	0	5	2	1
6x63	E3	0.44625	0	No	Yes	0	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
66.67	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
66.67	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
66.67	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
65.22	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
65.22	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
64.29	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
64.00	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
64.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
64.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
62.50	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
60.87	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
60.71	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
60.00	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
60.00	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
60.00	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
59.09	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
59.09	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
59.09	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
59.09	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
58.33	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
58.33	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
58.33	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
58.33	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
58.33	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
57.14	Single	5C1M	BU72	5C1M-μ-BU72
57.14	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
56.52	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
56.52	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
56.52	Single	7EZC	UKA	7EZC-A_2A-UKA
56.52	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
56.52	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
56.52	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
56.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
56.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
56.00	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
55.17	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
54.55	Single	2YDV	NECA	2YDV-A_2A-NECA
54.55	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
54.55	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
54.55	Single	5G53	NECA	5G53-A_2A-NECA-Gs
54.55	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
54.55	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
54.55	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
54.55	Single	8E0G	BU72	8E0G-μ-BU72
54.55	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
54.55	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
54.55	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
54.55	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
54.55	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
54.17	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
54.17	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
54.17	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
54.17	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
54.17	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
54.17	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
53.85	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
53.85	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
53.57	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
53.57	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
53.33	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
53.33	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
53.33	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
53.33	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
52.38	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
52.38	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
52.38	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
52.38	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
52.38	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
52.38	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
52.17	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
52.17	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
52.17	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
52.17	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
52.17	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
52.17	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
52.17	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
52.17	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
52.17	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
52.17	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
52.17	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
52.17	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
52.17	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
52.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
52.00	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
52.00	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
52.00	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
51.85	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
51.85	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
51.72	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
51.72	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
51.61	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
50.00	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
50.00	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
50.00	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
50.00	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
50.00	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
50.00	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
50.00	Single	5N2S	PSB36	5N2S-A₁-PSB36
50.00	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
50.00	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
50.00	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
50.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
50.00	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
50.00	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
50.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
50.00	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
50.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
50.00	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
50.00	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
50.00	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
50.00	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
50.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
50.00	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
50.00	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
50.00	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
50.00	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
50.00	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
50.00	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
50.00	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
50.00	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
50.00	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
50.00	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
50.00	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
50.00	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
50.00	Consensus	endothelin_off	Orthosteric Ligand	etb_off
50.00	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
50.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
50.00	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
50.00	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
50.00	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
50.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
50.00	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
50.00	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
48.28	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.28	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.28	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
48.28	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
48.28	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
48.15	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
48.15	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
48.15	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
48.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
48.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
48.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
48.00	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
48.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
48.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
48.00	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
48.00	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
48.00	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
48.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
48.00	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
48.00	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
48.00	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
47.83	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
47.83	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
47.83	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
47.83	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
47.83	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
47.83	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
47.83	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
47.83	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
47.83	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
47.83	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
47.83	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
47.83	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
47.83	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.83	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
47.83	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
47.83	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.83	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
47.83	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
47.83	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
47.83	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
47.83	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
47.83	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.83	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.83	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
47.83	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
47.62	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
47.62	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
47.62	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
47.62	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
47.62	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
47.62	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
47.62	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
47.62	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
47.62	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.62	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
47.62	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
47.62	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
46.88	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
46.67	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
46.43	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
46.43	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
46.43	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.43	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
46.43	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
46.15	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
46.15	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
46.15	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
46.15	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
46.15	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
46.15	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
46.15	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
46.15	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
46.15	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
45.83	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
45.83	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
45.83	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
45.83	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
45.83	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
45.83	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
45.83	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
45.83	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
45.83	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
45.83	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
45.83	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
45.83	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
45.83	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
45.83	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
45.83	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
45.83	Consensus	dp_off	Orthosteric Ligand	dp2_off
45.83	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
45.45	Single	3EML	ZM241385	3EML-A_2A-ZM241385
45.45	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
45.45	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
45.45	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
45.45	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
45.45	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
45.45	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
45.45	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
45.45	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
45.45	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
45.45	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
45.45	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
45.45	Single	6PS1	Timolol	6PS1-β₂-Timolol
45.45	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
45.45	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
45.45	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
45.45	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
45.45	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
45.45	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
45.45	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
45.45	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
45.45	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
45.45	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
45.45	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
45.45	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
45.45	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
45.45	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
45.45	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
45.45	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
45.45	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
45.45	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
45.45	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
45.45	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
45.45	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
45.45	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
45.45	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
45.45	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
45.45	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
45.45	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
45.45	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
45.45	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
45.45	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
45.45	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
45.45	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
45.45	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
45.45	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
45.45	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
45.45	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
45.45	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
45.45	Consensus	tar_on	Orthosteric Ligand	ta1_on
45.16	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
45.16	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
44.83	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
44.83	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
44.83	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
44.83	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
44.83	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
44.83	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.44	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
44.44	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
44.44	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
44.44	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
44.12	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
44.12	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
44.12	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
44.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
44.00	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
44.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
44.00	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
44.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
44.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
44.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
44.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
44.00	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
44.00	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
44.00	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
44.00	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
44.00	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
44.00	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
43.48	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
43.48	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
43.48	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
43.48	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
43.48	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
43.48	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
43.48	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
43.48	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
43.48	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
43.48	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
43.48	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
43.48	Single	6PS6	Timolol	6PS6-β₂-Timolol
43.48	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
43.48	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
43.48	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
43.48	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
43.48	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
43.48	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
43.48	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
43.48	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
43.48	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
43.48	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
43.48	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
43.48	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
43.48	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
43.48	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
43.48	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
43.48	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
43.48	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
43.48	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
43.48	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
43.48	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
43.48	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
43.48	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
43.48	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
43.48	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
43.48	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
43.33	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
43.33	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.33	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
43.33	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
42.86	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
42.86	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
42.86	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
42.86	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
42.86	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
42.86	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
42.86	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
42.86	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
42.86	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
42.86	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
42.86	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.86	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.86	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
42.86	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
42.86	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
42.86	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.86	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.86	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
42.86	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
42.86	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
42.86	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
42.86	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
42.86	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
42.86	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
42.86	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
42.86	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.31	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
42.31	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
42.31	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
42.31	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
42.31	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
42.31	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.94	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
41.94	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
41.67	Single	3P0G	BI167107	3P0G-β₂-BI167107
41.67	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
41.67	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
41.67	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
41.67	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
41.67	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
41.67	Single	5X93	K-8794	5X93-ET_B-K-8794
41.67	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
41.67	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
41.67	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
41.67	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
41.67	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
41.67	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
41.67	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
41.67	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
41.67	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
41.67	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
41.67	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
41.67	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
41.67	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
41.67	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
41.67	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
41.67	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
41.67	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
41.67	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
41.67	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
41.67	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
41.67	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
41.67	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
41.67	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
41.67	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
41.67	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
41.67	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
41.67	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
41.67	Consensus	histamine_off	Orthosteric Ligand	h1_off
41.67	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
41.67	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
41.67	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
40.91	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
40.91	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
40.91	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
40.91	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
40.91	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
40.91	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
40.91	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
40.91	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
40.91	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
40.91	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
40.91	Single	6TPG	EMPA	6TPG-OX₂-EMPA
40.91	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
40.91	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
40.91	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
40.91	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
40.91	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
40.91	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
40.91	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.91	Single	7T32	ZM241385	7T32-A_2A-ZM241385
40.91	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
40.91	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
40.91	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
40.91	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
40.91	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
40.91	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
40.91	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
40.91	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
40.91	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
40.91	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
40.91	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.91	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
40.91	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.91	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
40.91	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
40.91	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
40.91	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
40.91	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
40.91	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
40.91	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
40.74	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
40.74	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
40.00	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
40.00	Single	4LDE	BI167107	4LDE-β₂-BI167107
40.00	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
40.00	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
40.00	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
40.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
40.00	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
40.00	Single	6OS2	TRV026	6OS2-AT₁-TRV026
40.00	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
40.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
40.00	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
40.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
40.00	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
40.00	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
40.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
40.00	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
40.00	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
40.00	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
40.00	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
40.00	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
40.00	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
40.00	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
40.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
40.00	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
40.00	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
40.00	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
40.00	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
40.00	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
40.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
40.00	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
40.00	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
39.29	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
39.29	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
39.29	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
39.29	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
39.29	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
39.29	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
39.29	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
39.13	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
39.13	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
39.13	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
39.13	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
39.13	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
39.13	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
39.13	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
39.13	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
39.13	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
39.13	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
39.13	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
39.13	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
39.13	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
39.13	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
39.13	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
39.13	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
39.13	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
39.13	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
39.13	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
39.13	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
39.13	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
39.13	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
39.13	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
39.13	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
39.13	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
39.13	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
39.13	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
39.13	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
39.13	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
39.13	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
39.13	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
39.13	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
39.13	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
39.13	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
39.13	Consensus	a2_off	Orthosteric Ligand	a2a_off
39.13	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
39.13	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
39.13	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
39.13	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
38.71	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
38.71	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
38.46	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
38.46	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
38.46	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
38.46	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
38.46	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
38.46	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
38.46	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
38.46	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
38.46	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
38.46	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
38.46	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
38.46	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
38.46	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
38.46	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
38.46	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
38.24	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
38.10	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
38.10	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
38.10	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
38.10	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
38.10	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
38.10	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
38.10	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
38.10	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
38.10	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
38.10	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
38.10	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
38.10	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
38.10	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
38.10	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
38.10	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
38.10	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
38.10	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
38.10	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
37.93	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
37.50	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
37.50	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
37.50	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
37.50	Single	5WQC	EMPA	5WQC-OX₂-EMPA
37.50	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
37.50	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
37.50	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
37.50	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
37.50	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
37.50	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.50	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
37.50	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
37.50	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
37.50	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.50	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.50	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
37.50	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
37.50	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
37.50	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
37.50	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
37.50	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
37.50	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
37.50	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
37.50	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
37.50	Consensus	go_class-b1	Orthosteric Ligand	go_crf
37.50	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
37.50	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.04	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
37.04	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
37.04	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
37.04	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
37.04	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
37.04	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
37.04	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
37.04	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
37.04	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
37.04	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
37.04	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.67	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
36.67	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
36.67	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
36.67	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
36.67	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
36.67	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
36.67	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.67	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
36.67	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
36.36	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
36.36	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
36.36	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
36.36	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
36.36	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
36.36	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
36.36	Single	6AKX	A4R	6AKX-CCR5-A4R
36.36	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
36.36	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
36.36	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
36.36	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
36.36	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
36.36	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
36.36	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
36.36	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
36.36	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
36.36	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
36.36	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
36.36	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
36.36	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
36.36	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
36.36	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
36.36	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
36.36	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
36.36	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
36.36	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
36.36	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
36.36	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
36.36	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
36.36	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
36.36	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
36.36	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
36.36	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.36	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.36	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
36.36	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
36.36	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
36.36	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.36	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.36	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.36	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.36	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
36.36	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
36.36	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
36.36	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
36.36	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
36.36	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
36.36	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
36.36	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
36.36	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
36.36	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
36.36	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
36.11	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
36.00	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
36.00	Single	4DJH	JDTic	4DJH-κ-JDTic
36.00	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
36.00	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
36.00	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
36.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
36.00	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
36.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
36.00	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
36.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
36.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
36.00	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
36.00	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
36.00	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
36.00	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
36.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
36.00	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
36.00	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
36.00	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
36.00	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
36.00	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
36.00	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
36.00	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
36.00	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
36.00	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
36.00	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
36.00	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
36.00	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
36.00	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
36.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
36.00	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
36.00	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
36.00	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
36.00	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
36.00	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
36.00	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
35.71	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
35.71	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
35.71	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.71	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.71	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
35.71	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
35.71	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
35.71	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
35.71	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
35.48	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
35.48	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
35.48	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
35.48	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
35.48	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.48	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.48	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
34.78	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
34.78	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
34.78	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
34.78	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
34.78	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
34.78	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
34.78	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
34.78	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
34.78	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
34.78	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
34.78	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
34.78	Single	6IQL	L745870	6IQL-D₄-L745870
34.78	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
34.78	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
34.78	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
34.78	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
34.78	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
34.78	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
34.78	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
34.78	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
34.78	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
34.78	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
34.78	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
34.78	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.78	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
34.78	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
34.78	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
34.78	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
34.78	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
34.78	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
34.78	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
34.78	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
34.78	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
34.78	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
34.78	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
34.78	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
34.78	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
34.78	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
34.78	Consensus	sensory_off	Orthosteric Ligand	opsin_off
34.62	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
34.62	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
34.62	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
34.62	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
34.62	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
34.62	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
34.62	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
34.62	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
34.62	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.62	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.62	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
34.62	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.62	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
34.62	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.62	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.48	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
34.48	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
34.48	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
34.48	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.38	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
34.38	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
34.38	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
34.38	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
34.38	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
34.38	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
34.29	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
33.33	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
33.33	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
33.33	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
33.33	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
33.33	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
33.33	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
33.33	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
33.33	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
33.33	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
33.33	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
33.33	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
33.33	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
33.33	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
33.33	Single	6D27	CAY10471	6D27-DP₂-CAY10471
33.33	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
33.33	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
33.33	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
33.33	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
33.33	Single	7BU7	BI167107	7BU7-β₁-BI167107
33.33	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
33.33	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
33.33	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
33.33	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
33.33	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
33.33	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
33.33	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
33.33	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
33.33	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
33.33	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
33.33	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
33.33	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
33.33	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
33.33	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
33.33	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
33.33	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
33.33	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
33.33	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
33.33	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
33.33	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
33.33	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
33.33	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
33.33	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
33.33	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
33.33	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
33.33	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
33.33	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
33.33	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
33.33	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
33.33	Consensus	blt_on	Orthosteric Ligand	blt1_on
33.33	Consensus	cck_off	Orthosteric Ligand	ccka_off
33.33	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
33.33	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
33.33	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
33.33	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
33.33	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
33.33	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
33.33	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
33.33	Consensus	leuko_on	Orthosteric Ligand	blt_on
33.33	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
33.33	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
33.33	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
32.35	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
32.35	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
32.35	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
32.26	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
32.26	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
32.26	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
32.26	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
32.26	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
32.26	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
32.26	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
32.14	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
32.14	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
32.14	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
32.14	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
32.14	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
32.14	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
32.14	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
32.00	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
32.00	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
32.00	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
32.00	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
32.00	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
32.00	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
32.00	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
32.00	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
32.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
32.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
32.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
32.00	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
32.00	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
32.00	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
32.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
32.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
32.00	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.00	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
32.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
32.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
32.00	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
32.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
32.00	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
32.00	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
32.00	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
32.00	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
31.82	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
31.82	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
31.82	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
31.82	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
31.82	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
31.82	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
31.82	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
31.82	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
31.82	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
31.82	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
31.82	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
31.82	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
31.82	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
31.82	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
31.82	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
31.82	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
31.82	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
31.82	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
31.82	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
31.82	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
31.82	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
31.43	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
31.43	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
31.25	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
31.25	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
31.25	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
31.25	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
31.25	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
31.03	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
31.03	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
31.03	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
31.03	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
31.03	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
31.03	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.95	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
30.77	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
30.77	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
30.77	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
30.77	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
30.77	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
30.77	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
30.77	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
30.77	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
30.77	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
30.77	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
30.77	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
30.77	Single	7W41	PD176252	7W41-BB₂-PD176252
30.77	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
30.77	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.77	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
30.77	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
30.77	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
30.77	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
30.77	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
30.77	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.77	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
30.77	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
30.77	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
30.77	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
30.77	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
30.77	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
30.77	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
30.77	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
30.56	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
30.43	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
30.43	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
30.43	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
30.43	Single	5WS3	EMPA	5WS3-OX₂-EMPA
30.43	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
30.43	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
30.43	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
30.43	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
30.43	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
30.43	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
30.43	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
30.43	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
30.43	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.43	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.43	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
30.43	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
30.43	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
30.43	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
30.43	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
30.43	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
30.43	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
30.43	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
30.43	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
30.43	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.43	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.43	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
30.43	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
30.43	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
30.43	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
30.30	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
30.30	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
30.30	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
30.00	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
30.00	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.00	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
30.00	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
29.73	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
29.63	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
29.63	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
29.63	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
29.63	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
29.63	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
29.63	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
29.63	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
29.63	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
29.63	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
29.63	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
29.63	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
29.63	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
29.63	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
29.63	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
29.63	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
29.63	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
29.63	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
29.63	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
29.63	Consensus	gi_class-f	Other Ligand	gi_frizzled
29.63	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
29.63	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
29.41	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
29.41	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
29.17	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
29.17	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
29.17	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
29.17	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
29.17	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
29.17	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
29.17	Single	6VI4	JDTic	6VI4-κ-JDTic
29.17	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
29.17	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
29.17	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
29.17	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
29.17	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
29.17	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
29.17	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
29.17	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
29.17	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
29.17	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
29.17	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.17	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
29.17	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.17	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
29.17	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
29.17	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
29.17	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
29.17	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
29.17	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
29.17	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
29.17	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
29.17	Consensus	hcar_on	Orthosteric Ligand	hca_on
29.03	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
29.03	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
29.03	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
29.03	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.03	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
29.03	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
28.95	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
28.95	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
28.57	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
28.57	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
28.57	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
28.57	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
28.57	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
28.57	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
28.57	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
28.57	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
28.57	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
28.57	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
28.57	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
28.57	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
28.57	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
28.57	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
28.57	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
28.57	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
28.57	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
28.57	Consensus	sensory_on	Orthosteric Ligand	opsin_on
28.21	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
28.21	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
28.12	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
28.12	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.12	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
28.00	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
28.00	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
28.00	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
28.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
28.00	Single	5UEN	DU172	5UEN-A₁-DU172
28.00	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
28.00	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
28.00	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
28.00	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
28.00	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
28.00	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
28.00	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
28.00	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
28.00	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
28.00	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
28.00	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
28.00	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
28.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
28.00	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
28.00	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
28.00	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
28.00	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
28.00	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
28.00	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
28.00	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
28.00	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
28.00	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
27.91	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
27.78	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
27.78	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
27.59	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
27.59	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.59	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
27.59	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.59	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
27.59	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.59	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
27.27	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
27.27	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
27.27	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
27.27	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
27.27	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
27.27	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
27.27	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
27.27	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
27.27	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
27.27	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
27.27	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
27.27	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
27.27	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
27.27	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
27.27	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
27.27	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
27.27	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
27.03	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
27.03	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
27.03	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
26.92	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
26.92	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
26.92	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
26.92	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
26.92	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
26.92	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
26.92	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
26.92	Single	7C4S	S1P	7C4S-S1P₃-S1P
26.92	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
26.92	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
26.92	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
26.92	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
26.92	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
26.92	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
26.92	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
26.92	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
26.92	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
26.92	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
26.92	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
26.92	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
26.83	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
26.83	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
26.67	Single	7QA8	Peptide	7QA8-STE2-Peptide
26.67	Single	7QA8	Peptide	7QA8-STE2-Peptide
26.67	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
26.67	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
26.67	Consensus	class-d_off	Orthosteric Ligand	ste2_off
26.67	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
26.47	Single	6FJ3	PTH	6FJ3-PTH1-PTH
26.47	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
26.47	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
26.47	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
26.47	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
26.47	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
26.47	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
26.32	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
26.32	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
26.19	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
26.09	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
26.09	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
26.09	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
26.09	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
26.09	Single	6HLL	CP99994	6HLL-NK₁-CP99994
26.09	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
26.09	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
26.09	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
26.09	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
26.09	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
26.09	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
26.09	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
26.09	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
26.09	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.09	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
26.09	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
26.09	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
26.09	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
26.09	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
26.09	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
25.93	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
25.93	Single	5XR8	AM841	5XR8-CB₁-AM841
25.93	Single	5XRA	AM11542	5XRA-CB₁-AM11542
25.93	Single	6E59	L-760735	6E59-NK₁-L-760735
25.93	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
25.93	Single	7EPE	NAM563	7EPE-mGlu-NAM563
25.93	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
25.93	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
25.93	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.93	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.93	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.93	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
25.93	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
25.93	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
25.81	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
25.81	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
25.81	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
25.81	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
25.71	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
25.71	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
25.71	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
25.71	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
25.71	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
25.71	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
25.64	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
25.64	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
25.64	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
25.00	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
25.00	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
25.00	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
25.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
25.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
25.00	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
25.00	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
25.00	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
25.00	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
25.00	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
25.00	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
25.00	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
25.00	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
25.00	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
25.00	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
25.00	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
25.00	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
25.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
25.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
25.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
25.00	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
25.00	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
25.00	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
25.00	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
25.00	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
25.00	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
25.00	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
25.00	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
25.00	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
25.00	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
25.00	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
25.00	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
25.00	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
25.00	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
25.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
25.00	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
25.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
25.00	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
25.00	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
25.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
25.00	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
25.00	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
25.00	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
25.00	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
25.00	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
25.00	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
25.00	Consensus	nts_on	Orthosteric Ligand	nts1_on
25.00	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
25.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
25.00	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
24.32	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
24.24	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
24.24	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
24.24	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
24.24	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
24.24	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
24.24	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
24.14	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
24.14	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
24.14	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
24.14	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
24.14	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
24.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
24.00	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
24.00	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
24.00	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
24.00	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
24.00	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
24.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
24.00	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
24.00	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
24.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
24.00	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
24.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
24.00	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
24.00	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
24.00	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
24.00	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
24.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
24.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
24.00	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
24.00	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
24.00	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
24.00	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
24.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
24.00	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
24.00	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
23.81	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
23.81	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
23.81	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
23.81	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
23.81	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
23.68	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
23.68	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
23.53	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
23.53	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
23.33	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
23.33	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
23.33	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
23.33	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
23.33	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
23.33	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
23.33	Consensus	class-d_off	Orthosteric Ligand	ste2_off
23.33	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
23.08	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
23.08	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
23.08	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
23.08	Single	6IIV	Daltroban	6IIV-TP-Daltroban
23.08	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
23.08	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
23.08	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
23.08	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
23.08	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
23.08	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
23.08	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
23.08	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
23.08	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
22.86	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
22.86	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
22.86	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
22.86	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
22.86	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
22.86	Consensus	class-d_on	Orthosteric Ligand	ste2_on
22.86	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
22.86	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
22.73	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
22.73	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
22.73	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
22.73	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
22.73	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
22.73	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
22.58	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
22.58	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
22.22	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
22.22	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
22.22	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
22.22	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
22.22	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
22.22	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
22.22	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
22.22	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
22.22	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
22.22	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
22.22	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
21.88	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
21.88	Consensus	sst_off	Orthosteric Ligand	sst2_off
21.74	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
21.74	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
21.74	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
21.74	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
21.74	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
21.74	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
21.74	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.74	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
21.74	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
21.74	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
21.74	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
21.74	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
21.74	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
21.74	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
21.62	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
21.62	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
21.43	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
21.43	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
21.43	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
21.43	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
21.43	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
21.43	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
21.43	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
21.43	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
21.43	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
21.05	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
21.05	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
20.93	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
20.83	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
20.83	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
20.83	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
20.83	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
20.83	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
20.83	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
20.83	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
20.83	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
20.83	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
20.83	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
20.83	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
20.83	Consensus	class-t_on	Orthosteric Ligand	taste2_on
20.83	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
20.83	Consensus	go_protein	Orthosteric Ligand	go_chemokine
20.83	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
20.83	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
20.83	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
20.69	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
20.69	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
20.69	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
20.69	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
20.69	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
20.69	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
20.69	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
20.69	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.69	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
20.69	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
20.69	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
20.69	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
20.59	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
20.59	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
20.59	Consensus	class-d_on	Orthosteric Ligand	ste2_on
20.59	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
20.59	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
20.45	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
20.00	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
20.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
20.00	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
20.00	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
20.00	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
20.00	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
20.00	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
20.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
20.00	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
20.00	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
20.00	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
20.00	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
20.00	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
20.00	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
20.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
20.00	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
20.00	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
20.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
20.00	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
20.00	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
20.00	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
20.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
20.00	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
20.00	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
20.00	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
20.00	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
20.00	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
20.00	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.44	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
19.44	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
19.35	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
19.35	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.23	Single	6TPK	Retosiban	6TPK-OT-Retosiban
19.23	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
19.23	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
19.23	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
19.23	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
19.23	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
19.23	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
19.23	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
19.23	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
19.23	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
19.23	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
19.23	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
19.23	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
19.05	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
19.05	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
19.05	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
19.05	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
19.05	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.05	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
18.92	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
18.75	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
18.75	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
18.60	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
18.52	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
18.52	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
18.52	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
18.52	Single	6GPS	MK0812	6GPS-CCR2-MK0812
18.52	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
18.52	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
18.52	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
18.52	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
18.52	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
18.52	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
18.52	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
18.52	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
18.42	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
18.42	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
18.18	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
18.18	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
18.18	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
18.18	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
17.86	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
17.86	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
17.86	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
17.86	Single	6GPX	MK0812	6GPX-CCR2-MK0812
17.86	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
17.86	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
17.86	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
17.86	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
17.86	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
17.86	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
17.86	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
17.86	Consensus	ep_off	Orthosteric Ligand	ep4_off
17.65	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
17.65	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
17.39	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
17.39	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
17.24	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
17.24	Single	5V56	TC114	5V56-SMO-TC114
17.24	Single	7P2L	4YI	7P2L-mGlu₅-4YI
17.24	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
17.24	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
17.24	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
16.67	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
16.67	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
16.67	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
16.67	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
16.67	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
16.67	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
16.67	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
16.67	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
16.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
16.67	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
16.67	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
16.67	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
16.67	Consensus	nts_off	Orthosteric Ligand	nts1_off
16.67	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
16.67	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
16.00	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
16.00	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
16.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
16.00	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
16.00	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
16.00	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
16.00	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
16.00	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
15.79	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
15.79	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
15.62	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.62	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.62	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
15.62	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
15.38	Single	5U09	Taranabant	5U09-CB₁-Taranabant
15.38	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
15.38	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
15.38	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
15.38	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
15.38	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
15.38	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
15.38	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
15.38	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
15.38	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
15.38	Consensus	class-f_off	Orthosteric Ligand	smo_off
15.15	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
15.15	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
15.15	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
14.81	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
14.81	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
14.81	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
14.81	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.81	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
14.81	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
14.81	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
14.81	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
14.71	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
14.71	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
14.29	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
14.29	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	hcar_off	Orthosteric Ligand	succinate_off
14.29	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
13.89	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
13.79	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
13.79	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
13.79	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
13.79	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
13.79	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
13.79	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
13.79	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
13.33	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
13.33	Single	5V57	TC114	5V57-SMO-TC114
13.33	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
13.33	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
13.33	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.33	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
13.33	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
13.33	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
13.04	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
13.04	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
12.90	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
12.90	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
12.50	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
12.50	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
12.50	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
12.00	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
12.00	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
12.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
11.76	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
11.54	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
11.54	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
11.43	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.11	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.71	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.71	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
10.34	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
10.34	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
10.20	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
9.76	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
9.68	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
9.52	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
9.52	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
9.38	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.38	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.30	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
9.09	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
9.09	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
9.09	Single	8HS2	Fab046	8HS2-GPR20-Fab046
8.89	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
8.89	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
8.51	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
8.33	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
8.33	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
8.33	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
8.16	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
8.00	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
8.00	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
8.00	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
8.00	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
7.69	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
7.69	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
7.69	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
7.69	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
7.69	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
7.41	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
6.98	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
6.98	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
6.98	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
6.90	Single	8IYX	YL-365	8IYX-GPR34-YL-365
6.67	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
6.67	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
5.88	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
5.41	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.76	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
4.76	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
4.76	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
4.76	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
4.76	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
4.76	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
4.76	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.76	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.76	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.76	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
4.76	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
4.76	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.76	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.76	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.76	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.76	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.76	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
4.76	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
4.76	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
4.76	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
4.76	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
4.76	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
4.76	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
4.76	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
4.76	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
4.76	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.76	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.76	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
4.76	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
4.76	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.76	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
4.76	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
4.76	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
4.76	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
4.76	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
4.76	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
4.76	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Single	7FII	hCG	7FII-LH-hCG-6fuf
4.76	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
4.76	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
4.76	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
4.76	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
4.76	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.76	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.76	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.76	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.76	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
4.76	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
4.76	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.76	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.76	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
4.76	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
4.76	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.76	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.76	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.76	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.76	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.76	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
4.76	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
4.76	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
4.76	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
4.76	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
4.76	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
4.76	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
4.76	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
4.76	Single	7XW7	K1-70	7XW7-TSH-K1-70
4.76	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
4.76	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
4.76	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
4.76	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
4.76	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
4.76	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
4.76	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
4.76	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
4.76	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
4.76	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
4.76	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
4.76	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
4.76	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
4.76	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
4.76	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
4.76	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
4.76	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
4.76	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
4.76	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
4.76	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
4.76	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
4.76	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.76	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.76	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.76	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.76	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.76	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
4.76	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
4.76	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.76	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.76	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.76	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.76	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
4.76	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
4.76	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
4.76	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
4.76	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.76	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.76	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.76	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.76	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.76	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.76	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.76	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.76	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
4.76	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
4.76	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
4.76	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
4.76	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
4.76	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
4.76	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.76	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.76	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
4.76	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
4.76	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.76	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
4.76	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.76	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
4.76	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.76	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
4.76	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
4.76	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.76	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.76	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
4.76	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
4.76	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
4.76	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
4.76	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
4.76	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
4.76	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
4.76	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
4.76	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
4.76	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
4.76	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
4.55	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.55	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.55	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.55	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.55	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.55	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.55	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.55	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.55	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.55	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.35	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
4.35	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
4.17	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
4.17	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
4.17	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.17	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
4.17	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
4.17	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
4.17	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
4.17	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
4.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
4.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
4.00	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
3.85	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
3.70	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
3.70	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
3.57	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
3.45	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
3.33	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.33	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
3.23	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
3.23	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
3.12	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
3.03	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
2.94	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
2.94	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
2.63	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

Consensus Members
	Id	Members
	gq_amine	gq_muscarinic gq_histamine
	gq_peptide	gq_cck gq_angiotensin gq_bombesin gq_bradykinin

Net Summary
I_min	3.00063
Number of Linked Nodes	1061
Number of Links	1231
Number of Hubs	166
Number of Links mediated by Hubs	668
Number of Communities	17
Number of Nodes involved in Communities	208
Number of Links involved in Communities	309

Path Summary
Number Of Nodes in MetaPath	97
Number Of Links MetaPath	96
Number of Shortest Paths	5429946
Length Of Smallest Path	3
Average Path Length	40.9362
Length of Longest Path	64
Minimum Path Strength	0.551094
Average Path Strength	5.61093
Maximum Path Strength	23.8069
Minimum Path Correlation	0.700312
Average Path Correlation	0.985878
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.72414
Average % Of Corr. Nodes	26.0723
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.2927
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download gq_class-a.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.