psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D16	A:A:L12	5.43	No	No	0	4	2
2	A:A:D16	A:A:S13	10.31	No	No	0	4	7
3	A:A:V20	B:B:N88	5.91	No	No	0	3	7
4	A:A:E21	A:A:M25	9.47	No	No	0	2	4
5	A:A:R22	B:B:H91	4.51	No	No	0	5	5
6	A:A:E27	A:A:S23	4.31	No	No	3	6	7
7	A:A:S23	B:B:K89	4.59	No	Yes	3	7	9
8	A:A:I26	B:B:K89	7.27	No	Yes	0	9	9
9	A:A:E27	B:B:K89	9.45	No	Yes	3	6	9
10	A:A:D33	A:A:Q29	6.53	No	No	0	5	4
11	A:A:L30	B:B:L55	4.15	No	Yes	0	5	6
12	A:A:K34	A:A:Q31	6.78	Yes	No	0	4	4
13	A:A:D33	B:B:K78	6.91	No	No	0	5	8
14	A:A:K34	A:A:R38	6.19	Yes	No	17	4	4
15	A:A:K34	B:B:L55	4.23	Yes	Yes	0	4	6
16	A:A:K34	R:R:Y722	14.33	Yes	Yes	17	4	6
17	A:A:Q35	R:R:Y722	4.51	No	Yes	0	3	6
18	A:A:Q35	R:R:R724	5.84	No	No	0	3	7
19	A:A:R42	A:A:Y37	24.69	No	No	0	9	4
20	A:A:Y37	B:B:L55	4.69	No	Yes	0	4	6
21	A:A:Y37	B:B:A56	4	No	No	0	4	7
22	A:A:R38	R:R:Y722	5.14	No	Yes	17	4	6
23	A:A:H220	A:A:T40	10.95	No	No	0	7	7
24	A:A:F219	A:A:H41	6.79	Yes	No	0	8	6
25	A:A:H41	A:A:T242	8.21	No	No	0	6	8
26	A:A:H41	R:R:F719	7.92	No	Yes	0	6	9
27	A:A:F222	A:A:R42	4.28	Yes	No	0	7	9
28	A:A:I245	A:A:L43	5.71	Yes	No	0	7	7
29	A:A:C379	A:A:L43	4.76	No	No	0	8	7
30	A:A:L44	A:A:L46	4.15	No	No	0	9	8
31	A:A:F238	A:A:L44	17.05	Yes	No	0	9	9
32	A:A:I244	A:A:L44	4.28	No	No	0	8	9
33	A:A:K53	A:A:L45	5.64	No	Yes	7	9	8
34	A:A:L45	A:A:M221	7.07	Yes	Yes	7	8	8
35	A:A:D223	A:A:L45	5.43	No	Yes	7	9	8
36	A:A:I245	A:A:L45	4.28	Yes	Yes	7	7	8
37	A:A:L46	A:A:R231	9.72	No	Yes	0	8	9
38	A:A:D49	A:A:N50	5.39	No	Yes	11	7	6
39	A:A:D49	A:A:R265	4.76	No	Yes	11	7	9
40	A:A:D249	A:A:N50	6.73	No	Yes	11	8	6
41	A:A:N50	A:A:R265	9.64	Yes	Yes	11	6	9
42	A:A:G52	A:A:S51	3.71	No	No	0	9	9
43	A:A:S51	A:A:V247	4.85	No	No	0	9	7
44	A:A:G52	A:A:T55	3.64	No	No	0	9	9
45	A:A:D223	A:A:K53	4.15	No	No	7	9	9
46	A:A:I56	A:A:N292	8.5	No	No	0	7	9
47	A:A:I56	A:A:N371	4.25	No	Yes	0	7	9
48	A:A:T210	A:A:V57	4.76	No	No	0	7	7
49	A:A:I62	A:A:Q59	5.49	No	No	0	9	9
50	A:A:Q59	A:A:T369	5.67	No	No	0	9	9
51	A:A:F212	A:A:M60	7.46	Yes	No	0	9	9
52	A:A:H64	A:A:Y63	15.24	No	No	0	8	2
53	A:A:T369	A:A:Y63	3.75	No	No	0	9	2
54	A:A:H64	A:A:V214	8.3	No	No	0	8	6
55	A:A:F208	A:A:S205	3.96	No	No	0	5	7
56	A:A:G206	B:B:N119	5.09	No	No	0	8	9
57	A:A:F222	A:A:I207	3.77	Yes	No	1	7	9
58	A:A:I207	B:B:W99	3.52	No	Yes	1	9	9
59	A:A:D223	A:A:F208	8.36	No	No	0	9	5
60	A:A:F208	A:A:G225	4.52	No	No	0	5	9
61	A:A:E209	A:A:F222	11.66	No	Yes	0	9	7
62	A:A:H220	A:A:K211	11.79	No	No	0	7	4
63	A:A:F212	A:A:V214	3.93	Yes	No	0	9	6
64	A:A:F212	A:A:F219	12.86	Yes	Yes	0	9	8
65	A:A:F212	A:A:M221	3.73	Yes	Yes	0	9	8
66	A:A:F212	A:A:I375	5.02	Yes	No	0	9	9
67	A:A:F376	A:A:V214	3.93	Yes	No	0	8	6
68	A:A:D215	A:A:R373	10.72	No	No	0	5	5
69	A:A:D215	A:A:F376	9.55	No	Yes	0	5	8
70	A:A:F219	A:A:V217	3.93	Yes	No	0	8	5
71	A:A:V217	R:R:F719	5.24	No	Yes	0	5	9
72	A:A:V217	R:R:N720	5.91	No	No	0	5	9
73	A:A:F219	A:A:F376	4.29	Yes	Yes	0	8	8
74	A:A:C379	A:A:F219	5.59	No	Yes	0	8	8
75	A:A:F222	A:A:H220	10.18	Yes	No	0	7	7
76	A:A:I245	A:A:M221	4.37	Yes	Yes	7	7	8
77	A:A:F222	B:B:W99	16.04	Yes	Yes	1	7	9
78	A:A:Q227	A:A:V224	5.73	Yes	No	1	9	9
79	A:A:V224	A:A:W234	9.81	No	Yes	1	9	9
80	A:A:Q227	A:A:W234	8.76	Yes	Yes	1	9	9
81	A:A:Q227	B:B:L117	5.32	Yes	No	1	9	9
82	A:A:Q227	B:B:N119	5.28	Yes	No	0	9	9
83	A:A:Q227	B:B:Y145	7.89	Yes	Yes	1	9	8
84	A:A:D229	A:A:R228	3.57	No	Yes	0	8	9
85	A:A:E230	A:A:R228	6.98	No	Yes	1	9	9
86	A:A:R228	B:B:T164	5.17	Yes	No	0	9	6
87	A:A:R228	B:B:D186	3.57	Yes	No	1	9	9
88	A:A:E230	A:A:R232	3.49	No	No	0	9	8
89	A:A:E230	B:B:D186	3.9	No	No	1	9	9
90	A:A:R231	A:A:W234	9	Yes	Yes	1	9	9
91	A:A:I235	A:A:R231	3.76	No	Yes	1	9	9
92	A:A:D272	A:A:R231	13.1	No	Yes	0	8	9
93	A:A:R232	B:B:D228	14.29	No	Yes	0	8	9
94	A:A:K233	A:A:Q236	5.42	Yes	No	1	9	8
95	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
96	A:A:K233	B:B:M188	10.08	Yes	No	1	9	8
97	A:A:K233	B:B:C204	4.85	Yes	No	1	9	7
98	A:A:K233	B:B:D228	6.91	Yes	Yes	1	9	9
99	A:A:K233	B:B:N230	11.19	Yes	No	1	9	9
100	A:A:K233	B:B:D246	5.53	Yes	Yes	1	9	9
101	A:A:I235	A:A:W234	4.7	No	Yes	1	9	9
102	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
103	A:A:W234	B:B:L117	4.56	Yes	No	1	9	9
104	A:A:W234	B:B:Y145	4.82	Yes	Yes	1	9	8
105	A:A:I235	A:A:L282	7.14	No	No	0	9	9
106	A:A:Q236	A:A:W281	7.67	No	Yes	1	8	5
107	A:A:Q236	B:B:R314	7.01	No	Yes	1	8	8
108	A:A:C237	B:B:Y59	5.38	No	Yes	1	8	8
109	A:A:C237	B:B:M101	4.86	No	Yes	1	8	9
110	A:A:F238	A:A:V241	5.24	Yes	No	0	9	9
111	A:A:F238	B:B:W99	16.04	Yes	Yes	0	9	9
112	A:A:D240	A:A:N239	12.12	No	No	0	6	8
113	A:A:N239	B:B:K57	11.19	No	Yes	1	8	9
114	A:A:N239	B:B:W332	11.3	No	Yes	1	8	9
115	A:A:I244	A:A:I285	5.89	No	No	0	8	7
116	A:A:F290	A:A:I245	5.02	Yes	Yes	7	9	7
117	A:A:F246	A:A:F273	4.29	No	Yes	0	9	9
118	A:A:F246	A:A:L289	3.65	No	No	0	9	9
119	A:A:N292	A:A:V247	7.39	No	No	0	9	7
120	A:A:S250	A:A:V248	4.85	No	No	8	6	7
121	A:A:L291	A:A:V248	4.47	Yes	No	8	8	7
122	A:A:F345	A:A:V248	9.18	Yes	No	0	8	7
123	A:A:D249	A:A:S251	5.89	No	No	11	8	9
124	A:A:D249	A:A:K293	12.44	No	No	11	8	9
125	A:A:L291	A:A:S250	4.5	Yes	No	8	8	6
126	A:A:K293	A:A:S251	4.59	No	No	11	9	9
127	A:A:L296	A:A:S251	6.01	No	No	0	6	9
128	A:A:D252	A:A:N254	9.42	No	No	11	8	9
129	A:A:D252	A:A:R265	3.57	No	Yes	11	8	9
130	A:A:K300	A:A:Y253	5.97	No	Yes	25	9	8
131	A:A:S306	A:A:Y253	3.82	No	Yes	25	7	8
132	A:A:I308	A:A:Y253	10.88	No	Yes	0	7	8
133	A:A:Y253	A:A:Y311	3.97	Yes	No	0	8	6
134	A:A:N254	A:A:R265	6.03	No	Yes	11	9	9
135	A:A:N254	A:A:Y311	4.65	No	No	0	9	6
136	A:A:F312	A:A:L266	4.87	Yes	No	0	8	8
137	A:A:L270	A:A:Q267	5.32	No	No	0	6	4
138	A:A:N271	A:A:Q267	7.92	No	No	0	5	4
139	A:A:F312	A:A:Q267	5.86	Yes	No	0	8	4
140	A:A:D272	A:A:E268	11.69	No	No	0	8	9
141	A:A:F345	A:A:L270	10.96	Yes	No	0	8	6
142	A:A:I348	A:A:L270	4.28	No	No	0	4	6
143	A:A:K274	A:A:N271	4.2	No	No	0	5	5
144	A:A:F273	A:A:V287	9.18	Yes	No	0	9	6
145	A:A:F273	A:A:F345	7.5	Yes	Yes	0	9	8
146	A:A:F273	A:A:I348	6.28	Yes	No	0	9	4
147	A:A:I348	A:A:K274	14.54	No	No	0	4	5
148	A:A:I276	A:A:L282	4.28	No	No	0	8	9
149	A:A:N278	A:A:W277	6.78	No	Yes	19	8	6
150	A:A:V287	A:A:W277	4.9	No	Yes	0	6	6
151	A:A:S349	A:A:W277	8.65	Yes	Yes	0	7	6
152	A:A:S352	A:A:W277	3.71	No	Yes	19	5	6
153	A:A:G353	A:A:W277	4.22	No	Yes	19	4	6
154	A:A:H357	A:A:W277	27.51	No	Yes	19	7	6
155	A:A:N278	A:A:S352	8.94	No	No	19	8	5
156	A:A:L282	A:A:N279	10.98	No	No	0	9	8
157	A:A:R280	A:A:W281	4	No	Yes	0	5	5
158	A:A:R280	A:A:R283	9.6	No	Yes	0	5	3
159	A:A:W281	B:B:D290	10.05	Yes	Yes	1	5	6
160	A:A:W281	B:B:R314	21.99	Yes	Yes	1	5	8
161	A:A:R283	A:A:R356	5.33	Yes	No	0	3	2
162	A:A:H357	A:A:R283	4.51	No	Yes	0	7	3
163	A:A:I382	A:A:S286	10.84	No	No	0	6	8
164	A:A:F290	A:A:I288	3.77	Yes	Yes	7	9	9
165	A:A:I288	A:A:I375	5.89	Yes	No	7	9	9
166	A:A:D378	A:A:I288	11.2	No	Yes	0	7	9
167	A:A:L289	A:A:L291	8.3	No	Yes	0	9	8
168	A:A:F345	A:A:L289	6.09	Yes	No	0	8	9
169	A:A:F290	A:A:H362	6.79	Yes	No	0	9	9
170	A:A:F290	A:A:T364	6.49	Yes	Yes	7	9	9
171	A:A:F290	A:A:N371	8.46	Yes	Yes	7	9	9
172	A:A:F290	A:A:I375	5.02	Yes	No	7	9	9
173	A:A:F363	A:A:L291	4.87	Yes	Yes	8	5	8
174	A:A:N292	A:A:T364	7.31	No	Yes	0	9	9
175	A:A:K293	A:A:S366	4.59	No	No	0	9	9
176	A:A:L297	A:A:Q294	5.32	No	No	0	8	6
177	A:A:K338	A:A:Q294	5.42	No	No	8	5	6
178	A:A:F363	A:A:Q294	11.71	Yes	No	8	5	6
179	A:A:K300	A:A:S306	10.71	No	No	25	9	7
180	A:A:D331	A:A:L302	5.43	No	No	0	4	2
181	A:A:K305	A:A:S306	4.59	No	No	0	3	7
182	A:A:E309	A:A:K307	4.05	No	No	0	4	6
183	A:A:D310	A:A:K307	8.3	No	No	0	3	6
184	A:A:F315	A:A:I308	11.3	Yes	No	0	6	7
185	A:A:E309	A:A:F315	9.33	No	Yes	0	4	6
186	A:A:E314	A:A:F312	5.83	Yes	Yes	21	6	8
187	A:A:F312	A:A:F340	5.36	Yes	Yes	21	8	7
188	A:A:E314	A:A:P313	4.72	Yes	No	0	6	6
189	A:A:E314	A:A:F340	4.66	Yes	Yes	21	6	7
190	A:A:E314	A:A:E344	11.42	Yes	No	21	6	5
191	A:A:F315	A:A:R336	10.69	Yes	No	0	6	5
192	A:A:F315	A:A:F340	17.15	Yes	Yes	0	6	7
193	A:A:F340	A:A:Y318	13.41	Yes	No	0	7	6
194	A:A:D343	A:A:Y318	10.34	No	No	0	3	6
195	A:A:P321	A:A:T320	5.25	Yes	No	0	5	1
196	A:A:A324	A:A:P321	3.74	No	Yes	8	3	5
197	A:A:P321	A:A:Y339	6.95	Yes	Yes	8	5	3
198	A:A:A324	A:A:Y339	9.34	No	Yes	8	3	3
199	A:A:P326	A:A:T335	3.5	No	No	0	1	4
200	A:A:E327	A:A:E330	7.61	No	No	0	4	3
201	A:A:E330	A:A:V334	12.84	No	Yes	0	3	4
202	A:A:D331	A:A:P332	8.05	No	No	0	4	1
203	A:A:D331	A:A:R333	15.48	No	No	0	4	5
204	A:A:F363	A:A:K338	18.61	Yes	No	8	5	5
205	A:A:R342	A:A:Y339	8.23	Yes	Yes	8	4	3
206	A:A:F363	A:A:Y339	12.38	Yes	Yes	8	5	3
207	A:A:E344	A:A:F340	12.83	No	Yes	21	5	7
208	A:A:D343	A:A:R342	4.76	No	Yes	0	3	4
209	A:A:L346	A:A:R342	6.07	No	Yes	8	4	4
210	A:A:P361	A:A:R342	7.21	No	Yes	8	5	4
211	A:A:F363	A:A:R342	7.48	Yes	Yes	8	5	4
212	A:A:E344	A:A:R347	9.3	No	No	0	5	4
213	A:A:L346	A:A:S349	4.5	No	Yes	0	4	7
214	A:A:L346	A:A:P361	6.57	No	No	8	4	5
215	A:A:C359	A:A:S349	5.16	No	Yes	0	5	7
216	A:A:G353	A:A:H357	4.77	No	No	19	4	7
217	A:A:Y358	A:A:Y360	9.93	No	Yes	22	4	8
218	A:A:R385	A:A:Y358	17.49	Yes	No	22	5	4
219	A:A:D378	A:A:Y360	16.09	No	Yes	0	7	8
220	A:A:D381	A:A:Y360	12.64	No	Yes	22	8	8
221	A:A:I382	A:A:Y360	6.04	No	Yes	0	6	8
222	A:A:R385	A:A:Y360	4.12	Yes	Yes	22	5	8
223	A:A:H362	A:A:R374	9.03	No	Yes	0	9	4
224	A:A:D378	A:A:H362	12.61	No	No	0	7	9
225	A:A:N371	A:A:T364	4.39	Yes	Yes	7	9	9
226	A:A:R374	A:A:T364	3.88	Yes	Yes	7	4	9
227	A:A:D368	A:A:E370	5.2	Yes	No	0	9	4
228	A:A:D368	A:A:N371	4.04	Yes	Yes	7	9	9
229	A:A:D368	A:A:R374	9.53	Yes	Yes	7	9	4
230	A:A:N371	A:A:R374	3.62	Yes	Yes	7	9	4
231	A:A:N377	A:A:R373	6.03	No	No	0	4	5
232	A:A:F376	R:R:F719	7.5	Yes	Yes	0	8	9
233	A:A:Q384	A:A:R380	4.67	No	No	26	6	7
234	A:A:R380	R:R:V718	9.15	No	No	26	7	9
235	A:A:R380	R:R:F719	4.28	No	Yes	0	7	9
236	A:A:D381	A:A:R385	15.48	No	Yes	22	8	5
237	A:A:I383	A:A:M386	4.37	No	No	0	8	3
238	A:A:H387	A:A:I383	3.98	No	No	0	8	8
239	A:A:I383	R:R:F719	3.77	No	Yes	0	8	9
240	A:A:Q384	R:R:V718	7.16	No	No	26	6	9
241	A:A:Q384	R:R:Q803	7.68	No	No	0	6	9
242	A:A:L394	A:A:R385	4.86	No	Yes	0	8	5
243	A:A:R385	R:R:I807	8.77	Yes	No	0	5	8
244	A:A:H387	A:A:Q390	6.18	No	No	0	8	4
245	A:A:H387	R:R:A714	5.85	No	No	0	8	9
246	A:A:L388	A:A:L393	5.54	Yes	No	27	8	8
247	A:A:L388	A:A:L394	4.15	Yes	No	0	8	8
248	A:A:L388	R:R:L715	4.15	Yes	No	0	8	8
249	A:A:L388	R:R:L804	4.15	Yes	No	27	8	9
250	A:A:L394	A:A:R389	3.64	No	No	0	8	4
251	A:A:Q390	R:R:D651	10.44	No	No	0	4	9
252	A:A:Q390	R:R:P653	7.9	No	No	0	4	9
253	A:A:Y391	R:R:P653	13.91	No	No	28	4	9
254	A:A:Y391	R:R:H710	5.44	No	Yes	28	4	9
255	A:A:Y391	R:R:M711	8.38	No	No	0	4	9
256	A:A:L393	R:R:L804	11.07	No	No	27	8	9
257	A:A:L393	R:R:L830	5.54	No	No	0	8	8
258	B:B:D5	B:B:R8	4.76	No	No	0	1	3
259	B:B:L7	G:G:R13	3.64	No	No	0	8	6
260	B:B:E10	G:G:V16	4.28	No	No	0	8	8
261	B:B:L14	B:B:Q13	3.99	Yes	No	0	8	1
262	B:B:L14	G:G:L19	5.54	Yes	No	0	8	8
263	B:B:L14	G:G:K20	4.23	Yes	No	0	8	6
264	B:B:K15	G:G:L15	4.23	No	No	29	6	3
265	B:B:K15	G:G:L19	11.28	No	No	29	6	8
266	B:B:N16	B:B:R19	3.62	No	No	0	1	4
267	B:B:I18	B:B:R22	5.01	No	No	0	7	6
268	B:B:I18	G:G:E22	5.47	No	No	0	7	1
269	B:B:D20	B:B:R19	3.57	No	No	0	2	4
270	B:B:D258	B:B:R22	7.15	Yes	No	0	7	6
271	B:B:Q259	B:B:R22	4.67	Yes	No	0	6	6
272	B:B:D27	G:G:K29	11.06	No	No	0	8	5
273	B:B:D27	G:G:S31	8.83	No	No	0	8	3
274	B:B:A28	B:B:Q32	4.55	No	No	0	4	1
275	B:B:Q32	B:B:T29	4.25	No	No	0	1	3
276	B:B:L30	B:B:T34	5.9	No	Yes	0	5	5
277	B:B:L261	B:B:L30	8.3	No	No	0	5	5
278	B:B:L30	B:B:M262	4.24	No	Yes	0	5	4
279	B:B:M262	B:B:S31	6.13	Yes	No	0	4	1
280	B:B:I33	G:G:A34	4.87	No	No	0	3	7
281	B:B:I37	B:B:T34	4.56	No	Yes	0	2	5
282	B:B:L300	B:B:T34	5.9	No	Yes	0	6	5
283	B:B:T34	G:G:M38	4.52	Yes	No	0	5	6
284	B:B:I37	B:B:R283	5.01	No	Yes	0	2	9
285	B:B:I37	B:B:K301	4.36	No	Yes	0	2	5
286	B:B:R283	B:B:V40	5.23	Yes	No	30	9	3
287	B:B:D298	B:B:V40	10.22	Yes	No	30	9	3
288	B:B:I43	B:B:L284	7.14	No	No	0	3	5
289	B:B:L308	B:B:M45	8.48	No	No	0	7	4
290	B:B:R46	B:B:R48	7.46	No	No	0	5	7
291	B:B:K337	B:B:T47	12.01	Yes	No	9	6	3
292	B:B:T47	B:B:W339	12.13	No	Yes	9	3	9
293	B:B:N340	B:B:R48	9.64	No	No	5	9	7
294	B:B:R48	G:G:N59	4.82	No	Yes	5	7	9
295	B:B:R49	B:B:T87	5.17	No	No	0	7	5
296	B:B:I338	B:B:R49	5.01	No	No	0	5	7
297	B:B:R52	B:B:T50	11.64	No	No	0	7	3
298	B:B:K337	B:B:T50	7.51	Yes	No	0	6	3
299	B:B:L51	B:B:W82	19.36	No	Yes	0	9	9
300	B:B:L336	B:B:L51	6.92	No	No	0	7	9
301	B:B:F335	B:B:R52	11.76	Yes	No	9	4	7
302	B:B:R52	R:R:E646	4.65	No	No	9	7	6
303	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
304	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
305	B:B:H54	B:B:S72	6.97	Yes	No	0	9	9
306	B:B:H54	B:B:S74	11.16	Yes	No	3	9	9
307	B:B:D76	B:B:H54	6.3	Yes	Yes	3	9	9
308	B:B:H54	B:B:I80	13.26	Yes	No	3	9	8
309	B:B:D76	B:B:L55	8.14	Yes	Yes	0	9	6
310	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
311	B:B:K57	B:B:Y59	3.58	Yes	Yes	1	9	8
312	B:B:K57	B:B:Q75	13.56	Yes	No	1	9	9
313	B:B:K57	B:B:W332	22.05	Yes	Yes	1	9	9
314	B:B:Q75	B:B:Y59	5.64	No	Yes	1	9	8
315	B:B:M101	B:B:Y59	9.58	Yes	Yes	1	9	8
316	B:B:S316	B:B:Y59	6.36	No	Yes	1	9	8
317	B:B:W332	B:B:Y59	3.86	Yes	Yes	1	9	8
318	B:B:M61	B:B:W63	6.98	No	Yes	3	6	7
319	B:B:L70	B:B:M61	5.65	Yes	No	3	5	6
320	B:B:C317	B:B:M61	6.48	No	No	0	7	6
321	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
322	B:B:H62	B:B:R150	12.41	No	No	0	6	6
323	B:B:L70	B:B:W63	10.25	Yes	Yes	3	5	7
324	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
325	B:B:T321	B:B:W63	10.92	No	Yes	3	7	7
326	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
327	B:B:G64	B:B:Y105	5.79	No	Yes	0	5	6
328	B:B:D66	B:B:L69	9.5	No	No	0	8	5
329	B:B:S67	B:B:T321	7.99	No	No	3	5	7
330	B:B:D323	B:B:S67	10.31	No	No	3	7	5
331	B:B:D83	B:B:R68	14.29	No	No	5	8	5
332	B:B:R68	B:B:Y85	26.75	No	Yes	5	5	4
333	B:B:L69	B:B:V90	4.47	No	No	0	5	5
334	B:B:L69	B:B:Y105	7.03	No	Yes	0	5	6
335	B:B:L70	B:B:W82	4.56	Yes	Yes	3	5	9
336	B:B:L336	B:B:L70	4.15	No	Yes	0	7	5
337	B:B:C103	B:B:V71	3.42	No	No	0	8	8
338	B:B:V71	B:B:Y105	3.79	No	Yes	13	8	6
339	B:B:V112	B:B:V71	9.62	No	No	13	8	8
340	B:B:S72	B:B:W82	6.18	No	Yes	0	9	9
341	B:B:A73	B:B:C103	3.61	No	No	0	9	8
342	B:B:D76	B:B:S74	10.31	Yes	No	3	9	9
343	B:B:Q75	B:B:W99	5.48	No	Yes	1	9	9
344	B:B:D76	B:B:K78	5.53	Yes	No	0	9	8
345	B:B:G77	B:B:L95	5.13	No	No	0	8	8
346	B:B:I93	B:B:L79	9.99	Yes	No	0	7	7
347	B:B:L79	B:B:L95	4.15	No	No	0	7	8
348	B:B:C114	B:B:L79	6.35	No	No	0	8	7
349	B:B:I80	B:B:W82	12.92	No	Yes	3	8	9
350	B:B:I80	B:B:K89	8.72	No	Yes	3	8	9
351	B:B:I81	B:B:V90	4.61	No	No	13	7	5
352	B:B:H91	B:B:I81	6.63	No	No	13	5	7
353	B:B:I81	B:B:L126	4.28	No	No	13	7	5
354	B:B:K89	B:B:W82	9.28	Yes	Yes	3	9	9
355	B:B:D83	B:B:Y85	3.45	No	Yes	5	8	4
356	B:B:D83	B:B:T86	7.23	No	No	0	8	6
357	B:B:S84	G:G:F61	7.93	No	Yes	0	5	9
358	B:B:Y85	G:G:P60	13.91	Yes	Yes	5	4	9
359	B:B:Y85	G:G:F61	8.25	Yes	Yes	5	4	9
360	B:B:N88	B:B:T86	8.77	No	No	0	7	6
361	B:B:H91	B:B:V90	5.54	No	No	13	5	5
362	B:B:I93	B:B:Y124	8.46	Yes	Yes	0	7	6
363	B:B:I93	B:B:V133	7.68	Yes	No	0	7	4
364	B:B:L95	B:B:Y124	5.86	No	Yes	0	8	6
365	B:B:R96	B:B:V135	6.54	No	No	32	6	4
366	B:B:E138	B:B:R96	15.12	No	No	32	6	6
367	B:B:S97	B:B:W99	3.71	No	Yes	0	8	9
368	B:B:D118	B:B:S97	11.78	No	No	0	9	8
369	B:B:S98	B:B:W99	7.41	No	Yes	0	8	9
370	B:B:L117	B:B:W99	4.56	No	Yes	1	9	9
371	B:B:C114	B:B:V100	3.42	No	No	0	8	9
372	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
373	B:B:M101	B:B:Y145	7.18	Yes	Yes	1	9	8
374	B:B:C149	B:B:T102	5.07	No	No	0	8	8
375	B:B:G109	B:B:Y105	4.35	No	Yes	0	5	6
376	B:B:V112	B:B:Y105	3.79	No	Yes	13	8	6
377	B:B:L126	B:B:Y105	3.52	No	Yes	13	5	6
378	B:B:A106	B:B:F151	9.71	No	Yes	0	6	9
379	B:B:N110	B:B:S108	8.94	Yes	No	14	4	6
380	B:B:D154	B:B:S108	10.31	Yes	No	14	6	6
381	B:B:N110	B:B:Y111	3.49	Yes	Yes	14	4	4
382	B:B:K127	B:B:N110	5.6	No	Yes	0	4	4
383	B:B:D154	B:B:N110	5.39	Yes	Yes	14	6	4
384	B:B:I123	B:B:Y111	3.63	Yes	Yes	14	6	4
385	B:B:N125	B:B:Y111	11.63	No	Yes	0	4	4
386	B:B:S136	B:B:Y111	5.09	No	Yes	14	4	4
387	B:B:D154	B:B:Y111	4.6	Yes	Yes	14	6	4
388	B:B:L126	B:B:V112	5.96	No	No	13	5	8
389	B:B:C114	B:B:S122	3.44	No	No	0	8	8
390	B:B:G144	B:B:N119	5.09	No	No	0	8	9
391	B:B:C121	B:B:L139	6.35	No	Yes	0	8	9
392	B:B:C121	B:B:C149	3.64	No	No	0	8	8
393	B:B:S122	B:B:Y124	3.82	No	Yes	0	8	6
394	B:B:I123	B:B:S136	4.64	Yes	No	14	6	4
395	B:B:I123	B:B:L139	4.28	Yes	Yes	0	6	9
396	B:B:F151	B:B:I123	5.02	Yes	Yes	0	9	6
397	B:B:I123	B:B:I171	5.89	Yes	No	0	6	6
398	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
399	B:B:N125	B:B:T128	4.39	No	No	0	4	3
400	B:B:E130	B:B:N132	7.89	No	No	33	3	3
401	B:B:E130	B:B:R134	16.28	No	No	33	3	3
402	B:B:N132	B:B:R134	8.44	No	No	33	3	3
403	B:B:E138	B:B:V135	4.28	No	No	32	6	4
404	B:B:L139	B:B:R137	3.64	Yes	No	0	9	5
405	B:B:G174	B:B:R137	4.5	No	No	0	4	5
406	B:B:L139	B:B:W169	6.83	Yes	Yes	0	9	8
407	B:B:H142	B:B:L146	6.43	Yes	No	15	9	7
408	B:B:H142	B:B:T159	6.85	Yes	No	15	9	9
409	B:B:H142	B:B:S161	15.34	Yes	No	15	9	9
410	B:B:D163	B:B:H142	7.56	Yes	Yes	15	9	9
411	B:B:H142	B:B:W169	9.52	Yes	Yes	15	9	8
412	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
413	B:B:S147	B:B:Y145	3.82	No	Yes	0	9	8
414	B:B:G162	B:B:Y145	5.79	No	Yes	0	9	8
415	B:B:D186	B:B:Y145	12.64	No	Yes	1	9	8
416	B:B:M188	B:B:Y145	5.99	No	Yes	1	8	8
417	B:B:L146	B:B:T159	5.9	No	No	15	7	9
418	B:B:C148	B:B:R150	6.96	No	No	31	6	6
419	B:B:C148	B:B:L190	9.52	No	No	31	6	5
420	B:B:C149	B:B:I157	4.91	No	No	0	8	7
421	B:B:L190	B:B:R150	3.64	No	No	31	5	6
422	B:B:F151	B:B:I157	8.79	Yes	No	0	9	7
423	B:B:L152	B:B:Q156	10.65	No	No	0	3	5
424	B:B:L152	B:B:V158	4.47	No	No	0	3	5
425	B:B:L152	B:B:T196	4.42	No	No	0	3	1
426	B:B:D170	B:B:N155	5.39	No	No	23	9	3
427	B:B:E172	B:B:N155	3.94	No	No	23	6	3
428	B:B:L168	B:B:Q156	10.65	Yes	No	0	6	5
429	B:B:L168	B:B:V158	4.47	Yes	No	0	6	5
430	B:B:T159	B:B:W169	8.49	No	Yes	15	9	8
431	B:B:L190	B:B:S160	9.01	No	No	0	5	6
432	B:B:D163	B:B:S161	8.83	Yes	No	15	9	9
433	B:B:D163	B:B:T165	10.12	Yes	No	0	9	7
434	B:B:C166	B:B:F180	4.19	No	Yes	6	8	7
435	B:B:C166	B:B:F199	5.59	No	Yes	6	8	9
436	B:B:C166	B:B:S201	3.44	No	No	6	8	9
437	B:B:A167	B:B:W169	5.19	No	Yes	0	4	8
438	B:B:L168	B:B:T177	4.42	Yes	No	6	6	4
439	B:B:L168	B:B:T178	4.42	Yes	No	6	6	4
440	B:B:Q176	B:B:W169	15.33	No	Yes	0	4	8
441	B:B:D170	B:B:E172	7.8	No	No	23	9	6
442	B:B:D170	B:B:T173	13.01	No	Yes	23	9	5
443	B:B:E172	B:B:T173	4.23	No	Yes	23	6	5
444	B:B:Q176	B:B:T179	9.92	No	No	0	4	4
445	B:B:T177	B:B:T178	4.71	No	No	6	4	4
446	B:B:F180	B:B:T178	3.89	Yes	No	6	7	4
447	B:B:F180	B:B:F199	12.86	Yes	Yes	6	7	9
448	B:B:F180	B:B:W211	14.03	Yes	Yes	6	7	8
449	B:B:H183	B:B:V187	4.15	Yes	No	6	9	9
450	B:B:H183	B:B:S201	5.58	Yes	No	6	9	9
451	B:B:A203	B:B:H183	8.78	No	Yes	6	8	9
452	B:B:D205	B:B:H183	6.3	No	Yes	0	9	9
453	B:B:H183	B:B:K209	18.34	Yes	Yes	6	9	6
454	B:B:H183	B:B:W211	6.35	Yes	Yes	6	9	8
455	B:B:D205	B:B:T184	4.34	No	No	0	9	3
456	B:B:A203	B:B:V187	5.09	No	No	6	8	9
457	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
458	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
459	B:B:A193	B:B:F234	8.32	No	Yes	0	4	5
460	B:B:D195	B:B:R197	4.76	No	No	0	5	5
461	B:B:L198	B:B:L210	9.69	No	Yes	0	3	5
462	B:B:D212	B:B:L198	4.07	Yes	No	0	9	3
463	B:B:F199	B:B:W211	14.03	Yes	Yes	6	9	8
464	B:B:I232	B:B:V200	6.14	Yes	No	4	8	6
465	B:B:F234	B:B:V200	10.49	Yes	No	0	5	6
466	B:B:F241	B:B:V200	22.28	Yes	No	4	6	6
467	B:B:S201	B:B:W211	7.41	No	Yes	6	9	8
468	B:B:G202	B:B:I229	3.53	No	No	0	6	7
469	B:B:G202	B:B:I232	3.53	No	Yes	0	6	8
470	B:B:C204	B:B:D228	12.45	No	Yes	1	7	9
471	B:B:D205	B:B:S207	10.31	No	No	0	9	5
472	B:B:K209	B:B:W211	8.12	Yes	Yes	6	6	8
473	B:B:C218	B:B:K209	4.85	No	Yes	6	5	6
474	B:B:K209	B:B:T221	13.51	Yes	No	0	6	7
475	B:B:L210	B:B:R219	4.86	Yes	Yes	4	5	5
476	B:B:L210	B:B:Q220	6.65	Yes	Yes	4	5	7
477	B:B:L210	B:B:L255	9.69	Yes	Yes	4	5	6
478	B:B:C218	B:B:W211	5.22	No	Yes	6	5	8
479	B:B:D212	B:B:E215	12.99	Yes	No	4	9	3
480	B:B:D212	B:B:R219	14.29	Yes	Yes	4	9	5
481	B:B:E215	B:B:M217	5.41	No	No	4	3	3
482	B:B:E215	B:B:R219	4.65	No	Yes	4	3	5
483	B:B:M217	B:B:R219	9.93	No	Yes	4	3	5
484	B:B:M217	G:G:M21	4.33	No	No	0	3	2
485	B:B:C218	G:G:Q18	9.16	No	No	0	5	9
486	B:B:F222	B:B:Q220	10.54	Yes	Yes	4	8	7
487	B:B:L255	B:B:Q220	3.99	Yes	Yes	4	6	7
488	B:B:D258	B:B:Q220	11.75	Yes	Yes	4	7	7
489	B:B:T221	G:G:E22	8.47	No	No	0	7	1
490	B:B:F222	B:B:F241	13.93	Yes	Yes	4	8	6
491	B:B:F222	B:B:F253	12.86	Yes	Yes	4	8	6
492	B:B:D258	B:B:F222	8.36	Yes	Yes	4	7	8
493	B:B:G224	B:B:T223	3.64	No	No	0	6	2
494	B:B:E260	B:B:G224	4.91	No	No	0	6	6
495	B:B:H225	B:B:I229	7.95	Yes	No	0	9	7
496	B:B:H225	B:B:T243	10.95	Yes	No	0	9	8
497	B:B:H225	B:B:S245	12.55	Yes	No	20	9	9
498	B:B:D247	B:B:H225	10.08	Yes	Yes	20	9	9
499	B:B:H225	B:B:T249	5.48	Yes	Yes	20	9	6
500	B:B:H225	B:B:R251	14.67	Yes	Yes	20	9	8
501	B:B:D247	B:B:E226	12.99	Yes	No	0	9	3
502	B:B:D228	B:B:S227	4.42	Yes	No	0	9	6
503	B:B:D246	B:B:S227	4.42	Yes	No	0	9	6
504	B:B:D246	B:B:N230	6.73	Yes	No	1	9	9
505	B:B:F241	B:B:I232	5.02	Yes	Yes	4	6	8
506	B:B:I232	B:B:T243	4.56	Yes	No	0	8	8
507	B:B:F234	B:B:L255	4.87	Yes	Yes	0	5	6
508	B:B:F235	B:B:P236	8.67	Yes	Yes	16	6	7
509	B:B:F235	B:B:N237	10.87	Yes	Yes	16	6	5
510	B:B:F235	B:B:F278	10.72	Yes	Yes	16	6	7
511	B:B:F235	B:B:G282	4.52	Yes	No	16	6	9
512	B:B:F235	G:G:L37	4.87	Yes	No	0	6	8
513	B:B:F235	G:G:Y40	6.19	Yes	Yes	16	6	8
514	B:B:F278	B:B:P236	4.33	Yes	Yes	16	7	7
515	B:B:G282	B:B:P236	4.06	No	Yes	16	9	7
516	B:B:P236	G:G:Y40	5.56	Yes	Yes	16	7	8
517	B:B:G238	B:B:N237	5.09	No	Yes	0	7	5
518	B:B:N237	B:B:N239	6.81	Yes	No	0	5	2
519	B:B:N237	G:G:Y40	12.79	Yes	Yes	16	5	8
520	B:B:N239	B:B:R256	9.64	No	Yes	0	2	9
521	B:B:A240	G:G:L37	4.73	No	No	0	6	8
522	B:B:F241	B:B:F253	8.57	Yes	Yes	4	6	6
523	B:B:F241	B:B:L255	3.65	Yes	Yes	4	6	6
524	B:B:F253	B:B:T243	3.89	Yes	No	0	6	8
525	B:B:G244	B:B:I273	3.53	No	No	0	5	6
526	B:B:D247	B:B:S245	8.83	Yes	No	20	9	9
527	B:B:D247	B:B:T249	15.9	Yes	Yes	20	9	6
528	B:B:R251	B:B:T249	9.06	Yes	Yes	20	8	6
529	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
530	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
531	B:B:C250	B:B:I273	6.55	No	No	0	8	6
532	B:B:E260	B:B:R251	6.98	No	Yes	0	6	8
533	B:B:R251	B:B:T263	10.35	Yes	No	0	8	1
534	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
535	B:B:E260	B:B:F253	4.66	No	Yes	0	6	6
536	B:B:D254	B:B:R256	8.34	No	Yes	0	9	9
537	B:B:D254	G:G:A33	4.63	No	No	0	9	8
538	B:B:R256	G:G:I28	10.02	Yes	No	0	9	5
539	B:B:R256	G:G:D36	8.34	Yes	No	0	9	6
540	B:B:D258	G:G:R27	5.96	Yes	No	0	7	8
541	B:B:Q259	G:G:V30	7.16	Yes	No	0	6	8
542	B:B:L261	G:G:V30	4.47	No	No	0	5	8
543	B:B:M262	B:B:Y264	8.38	Yes	Yes	0	4	5
544	B:B:W297	B:B:Y264	11.58	No	Yes	0	8	5
545	B:B:D267	B:B:H266	5.04	No	No	0	3	4
546	B:B:H266	B:B:N268	12.75	No	No	12	4	4
547	B:B:H266	B:B:R304	9.03	No	Yes	12	4	5
548	B:B:I269	B:B:N268	5.66	Yes	No	12	4	4
549	B:B:N268	B:B:R304	9.64	No	Yes	12	4	5
550	B:B:I269	B:B:Y289	7.25	Yes	Yes	12	4	7
551	B:B:I269	B:B:N295	4.25	Yes	Yes	12	4	6
552	B:B:C271	B:B:Y289	4.03	No	Yes	12	5	7
553	B:B:C271	B:B:D291	6.22	No	No	12	5	8
554	B:B:I273	B:B:Y289	7.25	No	Yes	0	6	7
555	B:B:D290	B:B:T274	5.78	Yes	No	1	6	8
556	B:B:R314	B:B:T274	6.47	Yes	No	1	8	8
557	B:B:L285	B:B:V276	4.47	Yes	No	0	6	6
558	B:B:S277	B:B:V320	4.85	No	No	0	5	7
559	B:B:F278	B:B:G282	6.02	Yes	No	16	7	9
560	B:B:F278	B:B:L285	13.4	Yes	Yes	0	7	6
561	B:B:L284	B:B:S279	4.5	No	No	0	5	9
562	B:B:S279	G:G:D48	8.83	No	Yes	34	9	9
563	B:B:S279	G:G:L50	6.01	No	No	34	9	9
564	B:B:G324	B:B:K280	3.49	No	No	0	9	1
565	B:B:K280	G:G:E47	8.1	No	No	0	1	3
566	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
567	B:B:D298	B:B:R283	14.29	Yes	Yes	30	9	9
568	B:B:L300	B:B:R283	3.64	No	Yes	0	6	9
569	B:B:L284	B:B:V296	5.96	No	No	0	5	5
570	B:B:L286	B:B:V296	5.96	No	No	0	7	5
571	B:B:L286	B:B:V327	5.96	No	No	0	7	6
572	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
573	B:B:D291	B:B:Y289	5.75	No	Yes	12	8	7
574	B:B:N295	B:B:Y289	16.28	Yes	Yes	12	6	7
575	B:B:W297	B:B:Y289	7.72	No	Yes	0	8	7
576	B:B:D290	B:B:R314	20.25	Yes	Yes	1	6	8
577	B:B:D291	B:B:N293	4.04	No	No	0	8	5
578	B:B:F292	B:B:N313	4.83	No	No	0	4	7
579	B:B:N293	B:B:V307	4.43	No	No	0	5	3
580	B:B:A309	B:B:N293	4.69	No	No	0	3	5
581	B:B:C294	B:B:V315	5.12	No	No	0	5	7
582	B:B:C294	B:B:T329	5.07	No	Yes	0	5	8
583	B:B:N295	B:B:R304	7.23	Yes	Yes	12	6	5
584	B:B:N295	B:B:V307	4.43	Yes	No	0	6	3
585	B:B:R304	B:B:W297	8	Yes	No	0	5	8
586	B:B:D298	B:B:K301	8.3	Yes	Yes	0	9	5
587	B:B:D298	B:B:D303	3.99	Yes	No	0	9	2
588	B:B:L300	G:G:C41	4.76	No	No	0	6	8
589	B:B:L308	B:B:W339	22.78	No	Yes	0	7	9
590	B:B:H311	B:B:V315	5.54	Yes	No	0	9	7
591	B:B:H311	B:B:T329	6.85	Yes	Yes	0	9	8
592	B:B:H311	B:B:S331	12.55	Yes	No	9	9	9
593	B:B:D333	B:B:H311	5.04	Yes	Yes	9	9	9
594	B:B:H311	B:B:K337	13.1	Yes	Yes	9	9	6
595	B:B:D312	B:B:D333	11.98	No	Yes	0	5	9
596	B:B:D312	R:R:K647	15.21	No	No	0	5	9
597	B:B:N313	B:B:W332	4.52	No	Yes	0	7	9
598	B:B:R314	B:B:W332	18.99	Yes	Yes	1	8	9
599	B:B:S316	B:B:W332	4.94	No	Yes	1	9	9
600	B:B:L318	B:B:T329	4.42	No	Yes	0	6	8
601	B:B:V320	B:B:V327	4.81	No	No	0	7	6
602	B:B:D323	B:B:T321	7.23	No	No	3	7	7
603	B:B:M325	G:G:P49	8.39	No	No	5	5	8
604	B:B:M325	G:G:V54	4.56	No	Yes	5	5	6
605	B:B:M325	G:G:P60	8.39	No	Yes	5	5	9
606	B:B:A326	G:G:F61	4.16	No	Yes	0	7	9
607	B:B:V327	G:G:L50	4.47	No	No	0	6	9
608	B:B:T329	B:B:W339	9.7	Yes	Yes	0	8	9
609	B:B:G330	B:B:L336	5.13	No	No	0	5	7
610	B:B:D333	B:B:S331	5.89	Yes	No	9	9	9
611	B:B:D333	B:B:F335	14.33	Yes	Yes	9	9	4
612	B:B:F335	B:B:S334	5.28	Yes	No	0	4	4
613	B:B:F335	R:R:E646	8.16	Yes	No	9	4	6
614	B:B:K337	B:B:W339	5.8	Yes	Yes	9	6	9
615	B:B:I338	G:G:F61	6.28	No	Yes	0	5	9
616	B:B:N340	G:G:N59	14.98	No	Yes	5	9	9
617	G:G:L15	G:G:L19	4.15	No	No	29	3	8
618	G:G:M21	G:G:Q18	4.08	No	No	0	2	9
619	G:G:I25	G:G:R27	11.27	No	No	0	4	8
620	G:G:I28	G:G:K32	14.54	No	No	0	5	6
621	G:G:E42	G:G:M38	4.06	No	No	0	4	6
622	G:G:H44	G:G:Y40	14.16	No	Yes	0	6	8
623	G:G:E47	G:G:H44	4.92	No	No	0	3	6
624	G:G:D48	G:G:L50	5.43	Yes	No	34	9	9
625	G:G:D48	G:G:L51	9.5	Yes	No	0	9	7
626	G:G:P49	G:G:V54	5.3	No	Yes	5	8	6
627	G:G:P53	G:G:T52	3.5	No	No	0	7	5
628	G:G:P55	G:G:V54	3.53	No	Yes	5	7	6
629	G:G:E58	G:G:V54	5.7	No	Yes	5	6	6
630	G:G:N59	G:G:V54	4.43	Yes	Yes	5	9	6
631	G:G:E58	G:G:P55	18.86	No	No	5	6	7
632	G:G:N59	G:G:P60	4.89	Yes	Yes	5	9	9
633	G:G:F61	G:G:N59	3.62	Yes	Yes	5	9	9
634	G:G:F61	G:G:P60	8.67	Yes	Yes	5	9	9
635	L:L:?1	R:R:T624	10.26	Yes	No	0	0	9
636	L:L:?1	R:R:L667	9.64	Yes	No	0	0	9
637	L:L:?1	R:R:N668	5.46	Yes	No	0	0	9
638	L:L:?1	R:R:F671	18.17	Yes	No	2	0	9
639	L:L:?1	R:R:W838	5.67	Yes	Yes	2	0	9
640	L:L:?1	R:R:F856	21.81	Yes	Yes	2	0	9
641	L:L:?1	R:R:T861	4.4	Yes	No	0	0	8
642	R:R:L620	R:R:Y854	5.86	No	No	0	9	9
643	R:R:F622	R:R:T621	7.78	No	No	0	6	9
644	R:R:I623	R:R:I626	5.89	No	No	0	9	9
645	R:R:I623	R:R:Y854	7.25	No	No	0	9	9
646	R:R:S675	R:R:Y625	8.9	No	No	0	7	8
647	R:R:G627	R:R:L862	3.42	No	No	0	9	7
648	R:R:C628	R:R:L672	4.76	No	No	0	9	9
649	R:R:L630	R:R:L862	4.15	No	No	0	5	7
650	R:R:F865	R:R:L630	14.61	No	No	0	7	5
651	R:R:N668	R:R:S631	7.45	No	No	0	9	9
652	R:R:G864	R:R:S631	3.71	No	No	0	9	9
653	R:R:L669	R:R:S632	6.01	No	No	0	8	9
654	R:R:F634	R:R:I633	6.28	No	No	0	9	9
655	R:R:F634	R:R:F865	7.5	No	No	0	9	7
656	R:R:F634	R:R:F868	10.72	No	Yes	0	9	9
657	R:R:G864	R:R:L635	5.13	No	No	0	9	9
658	R:R:F868	R:R:V637	3.93	Yes	No	0	9	4
659	R:R:F868	R:R:T638	5.19	Yes	No	10	9	9
660	R:R:C872	R:R:T638	5.07	Yes	No	10	9	9
661	R:R:L639	R:R:L665	4.15	No	No	0	9	8
662	R:R:C872	R:R:T641	5.07	Yes	No	10	9	9
663	R:R:T641	R:R:W882	6.06	No	Yes	10	9	9
664	R:R:I648	R:R:Y642	9.67	Yes	Yes	0	8	9
665	R:R:S654	R:R:Y642	3.82	No	Yes	0	9	9
666	R:R:L657	R:R:Y642	4.69	No	Yes	0	9	9
667	R:R:I658	R:R:Y642	7.25	No	Yes	0	9	9
668	R:R:K875	R:R:Y642	3.58	No	Yes	0	9	9
669	R:R:I643	R:R:I658	4.42	No	No	0	7	9
670	R:R:F645	R:R:Q881	17.57	No	No	0	9	9
671	R:R:E646	R:R:R649	10.47	No	No	0	6	9
672	R:R:K647	R:R:Q881	5.42	No	No	0	9	9
673	R:R:I648	R:R:N877	5.66	Yes	No	10	8	8
674	R:R:I648	R:R:V878	4.61	Yes	Yes	10	8	9
675	R:R:I648	R:R:Q881	4.12	Yes	No	0	8	9
676	R:R:D651	R:R:S654	7.36	No	No	0	9	9
677	R:R:K655	R:R:Y652	5.97	No	Yes	17	9	8
678	R:R:Y652	R:R:Y722	5.96	Yes	Yes	17	8	6
679	R:R:Y652	R:R:Y726	9.93	Yes	Yes	0	8	8
680	R:R:I727	R:R:Y652	4.84	No	Yes	17	8	8
681	R:R:H710	R:R:P653	7.63	Yes	No	28	9	9
682	R:R:I727	R:R:K655	8.72	No	No	17	8	9
683	R:R:I656	R:R:W703	4.7	Yes	Yes	0	9	9
684	R:R:E707	R:R:I656	13.66	No	Yes	0	9	9
685	R:R:H710	R:R:I656	7.95	Yes	Yes	0	9	9
686	R:R:F730	R:R:I656	3.77	Yes	Yes	0	8	9
687	R:R:L657	R:R:Y871	3.52	No	No	0	9	8
688	R:R:Q659	R:R:W703	12.05	No	Yes	18	7	9
689	R:R:C731	R:R:Q659	4.58	No	No	18	8	7
690	R:R:Q659	R:R:W735	4.38	No	Yes	18	7	9
691	R:R:L664	R:R:S700	7.51	No	No	0	9	7
692	R:R:L664	R:R:Q863	5.32	No	Yes	0	9	9
693	R:R:L665	R:R:L669	4.15	No	No	0	8	8
694	R:R:F696	R:R:L666	13.4	No	No	0	9	5
695	R:R:F692	R:R:I670	3.77	No	No	0	7	6
696	R:R:F696	R:R:I670	5.02	No	No	0	9	6
697	R:R:F671	R:R:L693	4.87	No	Yes	2	9	9
698	R:R:F671	R:R:F769	4.29	No	No	2	9	9
699	R:R:I677	R:R:L673	4.28	No	No	0	8	8
700	R:R:D674	R:R:V689	13.15	Yes	No	0	9	8
701	R:R:D674	R:R:L693	6.79	Yes	Yes	2	9	9
702	R:R:D674	R:R:F769	10.75	Yes	No	2	9	9
703	R:R:C686	R:R:C770	7.28	No	No	0	9	9
704	R:R:G754	R:R:I687	5.29	No	No	0	9	9
705	R:R:C770	R:R:V689	3.42	No	No	0	9	8
706	R:R:A690	R:R:Y753	4	No	Yes	0	9	9
707	R:R:V691	R:R:Y753	6.31	No	Yes	0	6	9
708	R:R:F769	R:R:L693	3.65	No	Yes	2	9	9
709	R:R:L693	R:R:W771	4.56	Yes	No	2	9	9
710	R:R:H694	R:R:L698	9	Yes	No	0	9	9
711	R:R:H694	R:R:V742	6.92	Yes	No	24	9	9
712	R:R:H694	R:R:Y753	15.24	Yes	Yes	24	9	9
713	R:R:H694	R:R:I772	5.3	Yes	No	24	9	8
714	R:R:F696	R:R:Y695	5.16	No	Yes	0	9	9
715	R:R:V699	R:R:Y695	8.83	No	Yes	18	7	9
716	R:R:W735	R:R:Y695	8.68	Yes	Yes	18	9	9
717	R:R:F701	R:R:L697	6.09	No	No	0	9	9
718	R:R:L698	R:R:Y785	4.69	No	No	0	9	9
719	R:R:V699	R:R:W735	15.94	No	Yes	18	7	9
720	R:R:P738	R:R:V699	5.3	No	No	0	9	7
721	R:R:F701	R:R:F786	15	No	No	2	9	9
722	R:R:F701	R:R:W838	14.03	No	Yes	2	9	9
723	R:R:G734	R:R:T702	3.64	No	No	0	9	9
724	R:R:P738	R:R:T702	8.74	No	No	0	9	9
725	R:R:T702	R:R:Y785	6.24	No	No	0	9	9
726	R:R:L706	R:R:W703	5.69	No	Yes	0	9	9
727	R:R:C731	R:R:W703	3.92	No	Yes	18	8	9
728	R:R:G734	R:R:W703	7.04	No	Yes	0	9	9
729	R:R:W703	R:R:W735	9.37	Yes	Yes	18	9	9
730	R:R:G835	R:R:M704	3.49	No	No	2	9	9
731	R:R:M704	R:R:W838	5.82	No	Yes	2	9	9
732	R:R:M704	R:R:Q863	4.08	No	Yes	2	9	9
733	R:R:G705	R:R:I789	3.53	No	No	35	8	7
734	R:R:G705	R:R:N793	5.09	No	Yes	35	8	9
735	R:R:F730	R:R:L706	3.65	Yes	No	0	8	9
736	R:R:L706	R:R:V733	7.45	No	No	0	9	4
737	R:R:E707	R:R:L833	6.63	No	No	0	9	9
738	R:R:F709	R:R:L713	4.87	No	No	0	7	5
739	R:R:F709	R:R:F730	4.29	No	Yes	0	7	8
740	R:R:H710	R:R:Y726	6.53	Yes	Yes	0	9	8
741	R:R:L834	R:R:M711	4.24	No	No	0	9	9
742	R:R:V716	R:R:Y712	10.09	No	No	0	9	9
743	R:R:K717	R:R:Y712	5.97	No	No	0	9	9
744	R:R:M796	R:R:Y712	7.18	Yes	No	0	9	9
745	R:R:L713	R:R:T721	7.37	No	No	0	5	7
746	R:R:L713	R:R:Y726	5.86	No	Yes	0	5	8
747	R:R:I723	R:R:Y726	3.63	No	Yes	0	6	8
748	R:R:K725	R:R:R724	8.66	No	No	0	5	7
749	R:R:K729	R:R:R724	8.66	No	No	0	9	7
750	R:R:K725	R:R:L728	12.69	No	No	0	5	7
751	R:R:F730	R:R:Y726	13.41	Yes	Yes	0	8	8
752	R:R:V742	R:R:Y753	5.05	No	Yes	24	9	9
753	R:R:V745	R:R:Y753	3.79	No	Yes	0	8	9
754	R:R:V745	R:R:V777	4.81	No	No	0	8	7
755	R:R:N752	R:R:S749	4.47	No	No	0	8	6
756	R:R:N752	R:R:S774	11.92	No	No	0	8	7
757	R:R:I772	R:R:Y753	7.25	No	Yes	24	8	9
758	R:R:C770	R:R:I755	6.55	No	No	0	9	6
759	R:R:F778	R:R:W771	7.02	Yes	No	2	9	9
760	R:R:V782	R:R:W771	3.68	No	No	2	9	9
761	R:R:F778	R:R:Y779	7.22	Yes	No	0	9	9
762	R:R:F778	R:R:V782	7.87	Yes	No	2	9	9
763	R:R:F778	R:R:V783	5.24	Yes	No	0	9	9
764	R:R:F786	R:R:W838	8.02	No	Yes	2	9	9
765	R:R:F786	R:R:F842	7.5	No	No	0	9	9
766	R:R:I789	R:R:N793	4.25	No	Yes	35	7	9
767	R:R:F790	R:R:V794	7.87	No	No	0	9	2
768	R:R:F790	R:R:G839	6.02	No	No	0	9	9
769	R:R:F790	R:R:F842	10.72	No	No	0	9	9
770	R:R:L834	R:R:N793	5.49	No	Yes	0	9	9
771	R:R:M796	R:R:V799	4.56	Yes	No	0	9	9
772	R:R:F797	R:R:L801	7.31	No	No	0	9	7
773	R:R:F797	R:R:T831	3.89	No	No	0	9	8
774	R:R:F797	R:R:I836	11.3	No	No	0	9	9
775	R:R:I827	R:R:L801	4.28	No	No	0	7	7
776	R:R:R806	R:R:V802	3.92	No	No	0	9	7
777	R:R:Q803	R:R:R806	10.51	No	No	0	9	9
778	R:R:F870	R:R:G829	4.52	Yes	No	0	9	9
779	R:R:G829	R:R:Y871	4.35	No	No	0	9	8
780	R:R:F832	R:R:T831	3.89	No	No	0	6	8
781	R:R:F832	R:R:T837	5.19	No	Yes	0	6	9
782	R:R:F832	R:R:F866	21.43	No	No	0	6	9
783	R:R:L833	R:R:Y871	16.41	No	No	0	9	8
784	R:R:G835	R:R:W838	4.22	No	Yes	2	9	9
785	R:R:F840	R:R:T837	3.89	No	Yes	0	9	9
786	R:R:F859	R:R:T837	3.89	No	Yes	0	8	9
787	R:R:N860	R:R:T837	8.77	No	Yes	0	9	9
788	R:R:F856	R:R:W838	5.01	Yes	Yes	2	9	9
789	R:R:N860	R:R:W838	19.21	No	Yes	2	9	9
790	R:R:Q863	R:R:W838	4.38	Yes	Yes	2	9	9
791	R:R:F840	R:R:L855	4.87	No	No	0	9	9
792	R:R:A841	R:R:F856	8.32	No	Yes	0	9	9
793	R:R:F843	R:R:F852	9.65	No	Yes	0	9	9
794	R:R:A844	R:R:F856	4.16	No	Yes	0	9	9
795	R:R:G846	R:R:P847	4.06	No	No	0	8	8
796	R:R:N849	R:R:V848	4.43	No	No	0	8	7
797	R:R:N849	R:R:T851	4.39	No	No	36	8	5
798	R:R:F852	R:R:N849	8.46	Yes	No	36	9	8
799	R:R:F852	R:R:T851	3.89	Yes	No	36	9	5
800	R:R:F856	R:R:N860	8.46	Yes	No	2	9	9
801	R:R:F859	R:R:I858	3.77	No	No	0	8	9
802	R:R:F866	R:R:L862	4.87	No	No	0	9	7
803	R:R:I867	R:R:Q863	5.49	No	Yes	0	9	9
804	R:R:F865	R:R:I869	3.77	No	No	0	7	6
805	R:R:F866	R:R:I869	3.77	No	No	0	9	6
806	R:R:C872	R:R:F868	5.59	Yes	Yes	10	9	9
807	R:R:A873	R:R:F868	4.16	No	Yes	0	8	9
808	R:R:F868	R:R:W882	4.01	Yes	Yes	10	9	9
809	R:R:F870	R:R:I869	3.77	Yes	No	0	9	6
810	R:R:C872	R:R:W882	3.92	Yes	Yes	10	9	9
811	R:R:K875	R:R:N877	12.59	No	No	10	9	8
812	R:R:K875	R:R:V878	4.55	No	Yes	10	9	9
813	R:R:N877	R:R:V878	4.43	No	Yes	10	8	9
814	R:R:V878	R:R:W882	4.9	Yes	Yes	10	9	9
815	B:B:A73	B:B:V100	3.39	No	No	0	9	9
816	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
817	B:B:A231	B:B:V276	3.39	No	No	0	5	6
818	R:R:I737	R:R:P738	3.39	No	No	0	4	9
819	B:B:C148	B:B:T102	3.38	No	No	0	6	8
820	B:B:K78	B:B:P94	3.35	No	No	0	8	5
821	B:B:D246	B:B:G272	3.35	Yes	No	0	9	4
822	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
823	R:R:L746	R:R:P750	3.28	No	No	0	8	6
824	A:A:I26	B:B:A92	3.25	No	No	0	9	6
825	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
826	B:B:I18	G:G:A23	3.25	No	No	0	7	8
827	B:B:A28	B:B:I33	3.25	No	No	0	4	3
828	B:B:A305	B:B:I43	3.25	No	No	0	4	3
829	B:B:A248	B:B:I269	3.25	No	Yes	0	5	4
830	B:B:S160	B:B:V187	3.23	No	No	0	6	9
831	R:R:S774	R:R:V777	3.23	No	No	0	7	7
832	A:A:D323	A:A:P321	3.22	No	Yes	0	4	5
833	B:B:D38	B:B:P39	3.22	No	No	0	1	1
834	B:B:A302	B:B:M262	3.22	No	Yes	0	2	4
835	R:R:A708	R:R:M796	3.22	No	Yes	0	9	9
836	A:A:V301	A:A:V334	3.21	No	Yes	0	7	4
837	A:A:A303	A:A:K305	3.21	No	No	0	5	3
838	B:B:S31	B:B:T29	3.2	No	No	0	1	3
839	B:B:S275	B:B:T274	3.2	No	No	0	8	8
840	R:R:C661	R:R:L635	3.17	No	No	0	9	9
841	R:R:C661	R:R:L639	3.17	No	No	0	9	9
842	R:R:C661	R:R:L657	3.17	No	No	0	9	9
843	R:R:T781	R:R:V741	3.17	No	No	0	7	7
844	L:L:?1	R:R:C628	3.16	Yes	No	0	0	9
845	B:B:L7	G:G:A12	3.15	No	No	0	8	5
846	B:B:A11	G:G:L15	3.15	No	No	0	5	3
847	B:B:A242	B:B:L285	3.15	No	Yes	0	4	6
848	R:R:A857	R:R:L620	3.15	No	No	0	7	9
849	A:A:E327	A:A:P328	3.14	No	No	0	4	1
850	B:B:T165	B:B:T181	3.14	No	No	0	7	2
851	A:A:A48	A:A:N50	3.13	No	Yes	0	8	6
852	R:R:A708	R:R:N793	3.13	No	Yes	0	9	9
853	A:A:I341	A:A:S250	3.1	No	No	0	8	6
854	G:G:I9	G:G:S8	3.1	No	No	0	4	5
855	R:R:I748	R:R:S749	3.1	No	No	0	5	6
856	R:R:I827	R:R:S826	3.1	No	No	0	7	9
857	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
858	A:A:K338	A:A:V334	3.04	No	Yes	0	5	4
859	G:G:K20	G:G:V16	3.04	No	No	0	6	8
860	R:R:I780	R:R:T781	3.04	No	No	0	9	7
861	B:B:Q17	G:G:A23	3.03	No	No	0	4	8
862	B:B:A257	B:B:Q259	3.03	No	Yes	0	7	6
863	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
864	B:B:L318	B:B:S277	3	No	No	0	6	5
865	R:R:L672	R:R:S675	3	No	No	0	9	7
866	R:R:G684	R:R:R683	3	No	No	0	6	5
867	A:A:L302	A:A:V334	2.98	No	Yes	0	2	4
868	B:B:L168	B:B:V213	2.98	Yes	No	0	6	4
869	R:R:L804	R:R:V800	2.98	No	No	0	9	9
870	A:A:A372	A:A:H64	2.93	No	No	0	8	8
871	A:A:N218	A:A:T40	2.92	No	No	0	4	7
872	B:B:D322	B:B:T65	2.89	No	No	0	1	1
873	A:A:K28	A:A:K32	2.87	No	No	0	4	4
874	B:B:L7	G:G:I9	2.85	No	No	0	8	4
875	B:B:Q175	B:B:T173	2.83	No	Yes	0	4	5
876	A:A:E330	A:A:T335	2.82	No	No	0	3	4
877	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
878	B:B:G310	B:B:W339	2.81	No	Yes	0	5	9
879	B:B:D118	B:B:I120	2.8	No	No	0	9	6
880	R:R:C787	R:R:F842	2.79	No	No	0	6	9
881	A:A:A269	A:A:F246	2.77	No	No	0	9	9
882	B:B:A21	G:G:R27	2.77	No	No	0	4	8
883	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
884	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
885	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
886	R:R:L660	R:R:L664	2.77	No	No	0	9	9
887	R:R:L660	R:R:L833	2.77	No	No	0	9	9
888	R:R:A688	R:R:F685	2.77	No	No	0	8	8
889	R:R:A828	R:R:F870	2.77	No	Yes	0	5	9
890	R:R:H694	R:R:T781	2.74	Yes	No	0	9	7
891	A:A:K58	A:A:Q59	2.71	No	No	0	9	9
892	B:B:D5	B:B:L4	2.71	No	No	0	1	4
893	R:R:A739	R:R:Y695	2.67	No	Yes	0	9	9
894	B:B:L14	B:B:Q17	2.66	Yes	No	0	8	4
895	B:B:D153	B:B:D154	2.66	No	Yes	0	5	6
896	R:R:A663	R:R:W735	2.59	No	Yes	0	9	9
897	A:A:T325	A:A:Y339	2.5	No	Yes	0	2	3
898	B:B:F199	B:B:L192	2.44	Yes	No	0	9	5
899	B:B:F278	B:B:L252	2.44	Yes	No	0	7	7
900	R:R:F852	R:R:L855	2.44	Yes	No	0	9	9
901	B:B:D212	B:B:R214	2.38	Yes	No	0	9	9
902	B:B:Q9	B:B:R8	2.34	No	No	0	3	3
903	B:B:Q44	B:B:R42	2.34	No	No	0	4	2
904	R:R:E876	R:R:R879	2.33	No	No	0	8	9
905	R:R:F870	R:R:R825	2.14	Yes	No	0	9	9
906	B:B:G115	B:B:G116	2.11	No	No	0	9	9
907	B:B:G238	B:B:P194	2.03	No	No	0	7	4
908	R:R:R879	R:R:W882	2	No	Yes	0	9	9
909	R:R:C686	R:R:G754	1.96	No	No	0	9	9
910	R:R:C787	R:R:G784	1.96	No	No	0	6	8
911	A:A:A226	A:A:G206	1.95	No	No	0	9	8
912	A:A:A303	A:A:G304	1.95	No	No	0	5	5
913	B:B:A140	B:B:G141	1.95	No	No	0	5	5
914	B:B:A287	B:B:G288	1.95	No	No	0	6	7
915	R:R:A739	R:R:G736	1.95	No	No	0	9	9
916	B:B:A106	B:B:P107	1.87	No	No	0	6	6
917	A:A:G47	A:A:S51	1.86	No	No	0	9	9
918	B:B:G41	B:B:V40	1.84	No	No	0	1	3
919	B:B:G131	B:B:T128	1.82	No	No	0	4	3
920	B:B:G185	B:B:T164	1.82	No	No	0	5	6
921	B:B:G174	B:B:T173	1.82	No	Yes	0	4	5
922	B:B:G182	B:B:T181	1.82	No	No	0	6	2
923	R:R:G684	R:R:T682	1.82	No	No	0	6	4
924	B:B:A60	B:B:C103	1.81	No	No	0	7	8
925	G:G:P55	G:G:S57	1.78	No	No	0	7	8
926	R:R:P750	R:R:S749	1.78	No	No	0	6	6
927	R:R:G627	R:R:I626	1.76	No	No	0	9	9
928	B:B:P107	B:B:T65	1.75	No	No	0	6	1
929	B:B:C233	B:B:S277	1.72	No	No	0	3	5
930	B:B:A28	G:G:S31	1.71	No	No	0	4	3
931	R:R:G629	R:R:L672	1.71	No	No	0	9	9
932	A:A:A298	A:A:V334	1.7	No	Yes	0	4	4
933	A:A:A337	A:A:V301	1.7	No	No	0	8	7
934	B:B:A26	G:G:V30	1.7	No	No	0	3	8
935	R:R:G754	R:R:N773	1.7	No	No	0	9	5
936	B:B:K301	B:B:P39	1.67	Yes	No	0	5	1
937	B:B:A140	B:B:I120	1.62	No	No	0	5	6
938	R:R:S636	R:R:V637	1.62	No	No	0	9	4
939	R:R:S774	R:R:V776	1.62	No	No	0	7	5
940	R:R:D751	R:R:P750	1.61	No	No	0	4	6
941	R:R:A844	R:R:M853	1.61	No	No	0	9	8
942	A:A:S349	A:A:T350	1.6	Yes	No	0	7	4
943	R:R:S743	R:R:T747	1.6	No	No	0	7	7
944	R:R:T641	R:R:V640	1.59	No	No	0	9	8
945	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
946	R:R:A662	R:R:L639	1.58	No	No	0	4	9
947	A:A:T319	A:A:T320	1.57	No	No	0	5	1
948	A:A:A19	B:B:N88	1.56	No	No	0	4	7
949	A:A:A39	R:R:N720	1.56	No	No	0	5	9
950	A:A:C365	A:A:D368	1.56	No	Yes	0	8	9
951	B:B:A193	B:B:D195	1.54	No	No	0	4	5
952	R:R:A678	R:R:D674	1.54	No	Yes	0	9	9
953	R:R:I744	R:R:V740	1.54	No	No	0	8	5
954	R:R:I798	R:R:V794	1.54	No	No	0	6	2
955	R:R:I798	R:R:V802	1.54	No	No	0	6	7
956	R:R:M796	R:R:S795	1.53	Yes	No	0	9	4
957	A:A:K24	A:A:V20	1.52	No	No	0	4	3
958	A:A:M221	A:A:T210	1.51	Yes	No	0	8	7
959	A:A:G355	A:A:R389	1.5	No	No	0	2	4
960	B:B:T181	G:G:K14	1.5	No	No	0	2	5
961	A:A:L12	A:A:V20	1.49	No	No	0	2	3
962	R:R:L673	R:R:V689	1.49	No	No	0	8	8
963	A:A:D295	A:A:S366	1.47	No	No	0	9	9
964	R:R:D823	R:R:S826	1.47	No	No	0	7	9
965	A:A:D33	A:A:V36	1.46	No	No	0	5	2
966	B:B:N132	B:B:T128	1.46	No	No	0	3	3
967	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
968	G:G:A43	G:G:H44	1.46	No	No	0	5	6
969	B:B:L4	G:G:I9	1.43	No	No	0	4	4
970	R:R:I677	R:R:L679	1.43	No	No	0	8	8
971	B:B:K301	B:B:N35	1.4	Yes	No	0	5	1
972	G:G:D26	G:G:I28	1.4	No	No	0	4	5
973	R:R:A644	R:R:F645	1.39	No	No	0	7	9
974	R:R:L792	R:R:N793	1.37	No	Yes	0	6	9
975	A:A:K32	A:A:Q29	1.36	No	No	0	4	4
976	A:A:K32	A:A:Q35	1.36	No	No	0	4	3
977	A:A:K216	A:A:Q213	1.36	No	No	0	4	3
978	R:R:D823	R:R:L824	1.36	No	No	0	7	5
979	G:G:E17	G:G:K20	1.35	No	No	0	7	6
980	A:A:E299	A:A:L296	1.33	No	No	0	6	6
981	A:A:N218	A:A:Q213	1.32	No	No	0	4	3
982	B:B:N16	B:B:Q13	1.32	No	No	0	1	1
983	R:R:F685	R:R:T682	1.3	No	No	0	8	4
984	A:A:R61	A:A:T210	1.29	No	No	0	8	7
985	A:A:R283	A:A:T284	1.29	Yes	No	0	3	4
986	A:A:R389	A:A:T284	1.29	No	No	0	4	4
987	A:A:K34	R:R:R650	1.24	Yes	No	0	4	8
988	B:B:K23	B:B:R19	1.24	No	No	0	2	4
989	R:R:K655	R:R:R650	1.24	No	No	0	9	8
990	R:R:K880	R:R:R883	1.24	No	No	0	6	9
991	G:G:N59	G:G:R62	1.21	Yes	No	0	9	7
992	R:R:F778	R:R:N775	1.21	Yes	No	0	9	6
993	R:R:I677	R:R:W676	1.17	No	No	0	8	9
994	R:R:L679	R:R:Y680	1.17	No	No	0	8	8
995	G:G:E17	G:G:R13	1.16	No	No	0	7	6
996	R:R:W845	R:R:Y779	0.96	No	No	0	8	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:K34	6.554	5	17	4
2	A:A:L45	5.605	4	7	8
3	A:A:N50	6.2225	4	11	6
4	A:A:F212	6.6	5	0	9
5	A:A:F219	6.692	5	0	8
6	A:A:M221	4.17	4	7	8
7	A:A:F222	9.186	5	1	7
8	A:A:Q227	6.596	5	1	9
9	A:A:R228	4.8225	4	1	9
10	A:A:R231	8.895	4	1	9
11	A:A:K233	6.79429	7	1	9
12	A:A:W234	6.52286	7	1	9
13	A:A:F238	10.585	4	0	9
14	A:A:I245	4.845	4	7	7
15	A:A:Y253	6.16	4	25	8
16	A:A:R265	6	4	11	9
17	A:A:F273	6.8125	4	0	9
18	A:A:W277	9.295	6	19	6
19	A:A:W281	10.9275	4	1	5
20	A:A:R283	5.1825	4	0	3
21	A:A:I288	6.0275	4	7	9
22	A:A:F290	5.925	6	7	9
23	A:A:L291	5.535	4	8	8
24	A:A:F312	5.48	4	21	8
25	A:A:E314	6.6575	4	21	6
26	A:A:F315	12.1175	4	0	6
27	A:A:P321	4.79	4	8	5
28	A:A:V334	4.754	5	0	4
29	A:A:Y339	7.88	5	8	3
30	A:A:F340	10.682	5	21	7
31	A:A:R342	6.75	5	8	4
32	A:A:F345	8.4325	4	0	8
33	A:A:S349	4.9775	4	0	7
34	A:A:Y360	9.764	5	22	8
35	A:A:F363	11.01	5	8	5
36	A:A:T364	5.5175	4	7	9
37	A:A:D368	5.0825	4	7	9
38	A:A:N371	4.952	5	7	9
39	A:A:R374	6.515	4	7	4
40	A:A:F376	6.3175	4	0	8
41	A:A:R385	10.144	5	22	5
42	A:A:L388	4.4975	4	27	8
43	B:B:L14	4.105	4	0	8
44	B:B:T34	5.22	4	0	5
45	B:B:H54	9.128	5	3	9
46	B:B:L55	5.3025	4	0	6
47	B:B:K57	12.595	4	1	9
48	B:B:Y59	5.73333	6	1	8
49	B:B:W63	6.63167	6	3	7
50	B:B:L70	6.1525	4	3	5
51	B:B:D76	6.982	5	3	9
52	B:B:W82	10.46	5	3	9
53	B:B:Y85	13.09	4	5	4
54	B:B:K89	7.13333	6	3	9
55	B:B:I93	7.38	4	0	7
56	B:B:W99	8.10857	7	1	9
57	B:B:M101	6.2775	4	1	9
58	B:B:Y105	4.66143	7	13	6
59	B:B:N110	5.855	4	14	4
60	B:B:Y111	5.688	5	14	4
61	B:B:I123	4.692	5	14	6
62	B:B:Y124	6.1125	4	0	6
63	B:B:L139	5.275	4	0	9
64	B:B:H142	9.14	5	15	9
65	B:B:Y145	6.46375	8	1	8
66	B:B:F151	5.812	5	0	9
67	B:B:D154	5.74	4	14	6
68	B:B:D163	8.435	4	15	9
69	B:B:L168	5.388	5	6	6
70	B:B:W169	9.072	5	15	8
71	B:B:T173	5.4725	4	23	5
72	B:B:F180	7.596	5	6	7
73	B:B:H183	8.25	6	6	9
74	B:B:F199	8.73	4	6	9
75	B:B:K209	11.205	4	6	6
76	B:B:L210	7.7225	4	4	5
77	B:B:W211	9.19333	6	6	8
78	B:B:D212	8.4325	4	4	9
79	B:B:R219	8.4325	4	4	5
80	B:B:Q220	8.2325	4	4	7
81	B:B:F222	11.4225	4	4	8
82	B:B:H225	9.02	7	20	9
83	B:B:D228	9.5175	4	1	9
84	B:B:I232	4.778	5	4	8
85	B:B:F234	7.5725	4	0	5
86	B:B:F235	7.64	6	16	6
87	B:B:P236	5.655	4	16	7
88	B:B:N237	8.89	4	16	5
89	B:B:F241	9.37	6	4	6
90	B:B:D246	5.0075	4	1	9
91	B:B:D247	11.95	4	20	9
92	B:B:T249	8.81	4	20	6
93	B:B:R251	10.265	4	20	8
94	B:B:F253	7.495	4	4	6
95	B:B:L255	5.55	4	4	6
96	B:B:R256	9.085	4	0	9
97	B:B:D258	8.305	4	4	7
98	B:B:Q259	4.4775	4	0	6
99	B:B:M262	5.4925	4	0	4
100	B:B:Y264	7.4625	4	0	5
101	B:B:I269	5.1025	4	12	4
102	B:B:F278	7.382	5	16	7
103	B:B:R283	7.0425	4	30	9
104	B:B:L285	5.65	4	0	6
105	B:B:Y289	7.66	7	12	7
106	B:B:D290	9.8575	4	1	6
107	B:B:N295	8.0475	4	12	6
108	B:B:D298	9.2	4	30	9
109	B:B:K301	3.9325	4	0	5
110	B:B:R304	8.475	4	12	5
111	B:B:H311	8.616	5	9	9
112	B:B:R314	14.942	5	1	8
113	B:B:T329	6.51	4	0	8
114	B:B:W332	10.9433	6	1	9
115	B:B:D333	9.31	4	9	9
116	B:B:F335	9.8825	4	9	4
117	B:B:K337	9.605	4	9	6
118	B:B:W339	10.644	5	9	9
119	G:G:Y40	9.675	4	16	8
120	G:G:D48	8.5175	4	34	9
121	G:G:V54	4.704	5	5	6
122	G:G:N59	5.65833	6	5	9
123	G:G:P60	8.965	4	5	9
124	G:G:F61	6.485	6	5	9
125	L:L:?1	9.82125	8	2	0
126	R:R:Y642	5.802	5	0	9
127	R:R:I648	6.015	4	10	8
128	R:R:Y652	6.675	4	17	8
129	R:R:I656	7.52	4	0	9
130	R:R:D674	8.0575	4	2	9
131	R:R:L693	4.9675	4	2	9
132	R:R:H694	7.84	5	24	9
133	R:R:Y695	6.335	4	18	9
134	R:R:W703	7.12833	6	18	9
135	R:R:H710	6.8875	4	28	9
136	R:R:F719	5.742	5	0	9
137	R:R:Y722	7.485	4	17	6
138	R:R:Y726	7.872	5	0	8
139	R:R:F730	6.28	4	0	8
140	R:R:W735	8.192	5	18	9
141	R:R:Y753	6.94	6	24	9
142	R:R:F778	5.712	5	2	9
143	R:R:N793	3.866	5	35	9
144	R:R:M796	4.1225	4	0	9
145	R:R:T837	5.435	4	0	9
146	R:R:W838	8.295	8	2	9
147	R:R:F852	6.11	4	36	9
148	R:R:F856	9.552	5	2	9
149	R:R:Q863	4.8175	4	2	9
150	R:R:F868	5.6	6	10	9
151	R:R:F870	3.3	4	0	9
152	R:R:C872	4.9125	4	10	9
153	R:R:V878	4.6225	4	10	9
154	R:R:W882	4.178	5	10	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:S84	G:G:F61	20.1613	7.93	No	Yes	0	5	9
2	B:B:S84	B:B:W63	20.8506	4.94	No	Yes	0	5	7
3	B:B:L70	B:B:W63	24.9642	10.25	Yes	Yes	3	5	7
4	B:B:L70	B:B:W82	28.3989	4.56	Yes	Yes	3	5	9
5	B:B:S72	B:B:W82	15.551	6.18	No	Yes	0	9	9
6	B:B:H54	B:B:S72	15.8863	6.97	Yes	No	0	9	9
7	B:B:D76	B:B:H54	34.4764	6.3	Yes	Yes	3	9	9
8	B:B:D76	B:B:K78	100	5.53	Yes	No	0	9	8
9	B:B:K78	B:B:P94	99.8811	3.35	No	No	0	8	5
10	B:B:I93	B:B:P94	99.6474	3.39	Yes	No	0	7	5
11	B:B:I93	B:B:L79	97.0821	9.99	Yes	No	0	7	7
12	B:B:C114	B:B:L79	96.3716	6.35	No	No	0	8	7
13	B:B:C114	B:B:V100	96.448	3.42	No	No	0	8	9
14	B:B:A73	B:B:V100	96.2091	3.39	No	No	0	9	9
15	B:B:A73	B:B:C103	95.9699	3.61	No	No	0	9	8
16	B:B:C103	B:B:V71	95.4904	3.42	No	No	0	8	8
17	B:B:V71	B:B:Y105	93.7381	3.79	No	Yes	13	8	6
18	B:B:I80	B:B:W82	15.5498	12.92	No	Yes	3	8	9
19	B:B:H54	B:B:I80	17.9584	13.26	Yes	No	3	9	8
20	B:B:D76	B:B:L55	89.1172	8.14	Yes	Yes	0	9	6
21	A:A:K34	B:B:L55	85.0212	4.23	Yes	Yes	0	4	6
22	A:A:K34	R:R:Y722	84.3419	14.33	Yes	Yes	17	4	6
23	A:A:Y37	B:B:L55	60.8874	4.69	No	Yes	0	4	6
24	A:A:R42	A:A:Y37	93.0666	24.69	No	No	0	9	4
25	B:B:A56	B:B:D76	32.6772	4.63	No	Yes	0	7	9
26	A:A:Y37	B:B:A56	32.6655	4	No	No	0	4	7
27	A:A:F222	A:A:R42	92.8588	4.28	Yes	No	0	7	9
28	R:R:Y652	R:R:Y722	85.1694	5.96	Yes	Yes	17	8	6
29	R:R:Y652	R:R:Y726	85.3982	9.93	Yes	Yes	0	8	8
30	R:R:H710	R:R:Y726	53.9112	6.53	Yes	Yes	0	9	8
31	R:R:H710	R:R:P653	29.7851	7.63	Yes	No	28	9	9
32	A:A:Q390	R:R:P653	31.8099	7.9	No	No	0	4	9
33	A:A:H387	A:A:Q390	37.6598	6.18	No	No	0	8	4
34	A:A:H387	A:A:I383	37.5554	3.98	No	No	0	8	8
35	A:A:I383	R:R:F719	37.4816	3.77	No	Yes	0	8	9
36	A:A:H41	R:R:F719	11.4777	7.92	No	Yes	0	6	9
37	A:A:F219	A:A:H41	11.2505	6.79	Yes	No	0	8	6
38	A:A:V217	R:R:F719	11.6375	5.24	No	Yes	0	5	9
39	A:A:F219	A:A:V217	11.2966	3.93	Yes	No	0	8	5
40	A:A:F376	R:R:F719	23.5716	7.5	Yes	Yes	0	8	9
41	A:A:F219	A:A:F376	11.3424	4.29	Yes	Yes	0	8	8
42	A:A:F212	A:A:F219	32.1327	12.86	Yes	Yes	0	9	8
43	A:A:F376	A:A:V214	11.9654	3.93	Yes	No	0	8	6
44	A:A:F212	A:A:V214	11.0816	3.93	Yes	No	0	9	6
45	A:A:F222	B:B:W99	91.0267	16.04	Yes	Yes	1	7	9
46	B:B:L117	B:B:W99	15.9105	4.56	No	Yes	1	9	9
47	B:B:Q75	B:B:W99	64.1194	5.48	No	Yes	1	9	9
48	B:B:K57	B:B:Q75	31.555	13.56	Yes	No	1	9	9
49	B:B:K57	B:B:W332	30.758	22.05	Yes	Yes	1	9	9
50	B:B:R314	B:B:W332	60.3429	18.99	Yes	Yes	1	8	9
51	A:A:W281	B:B:R314	57.1968	21.99	Yes	Yes	1	5	8
52	A:A:R280	A:A:W281	59.0401	4	No	Yes	0	5	5
53	A:A:R280	A:A:R283	58.6514	9.6	No	Yes	0	5	3
54	A:A:H357	A:A:R283	68.6926	4.51	No	Yes	0	7	3
55	A:A:H357	A:A:W277	67.2949	27.51	No	Yes	19	7	6
56	A:A:S349	A:A:W277	45.4034	8.65	Yes	Yes	0	7	6
57	A:A:L346	A:A:S349	43.3065	4.5	No	Yes	0	4	7
58	A:A:L346	A:A:R342	41.8986	6.07	No	Yes	8	4	4
59	A:A:D343	A:A:R342	23.6338	4.76	No	Yes	0	3	4
60	A:A:D343	A:A:Y318	22.9237	10.34	No	No	0	3	6
61	A:A:F340	A:A:Y318	22.2149	13.41	Yes	No	0	7	6
62	A:A:F315	A:A:F340	18.7541	17.15	Yes	Yes	0	6	7
63	A:A:F315	A:A:I308	15.1681	11.3	Yes	No	0	6	7
64	A:A:I308	A:A:Y253	14.4498	10.88	No	Yes	0	7	8
65	A:A:Y253	A:A:Y311	10.1313	3.97	Yes	No	0	8	6
66	B:B:Q75	B:B:Y59	32.3686	5.64	No	Yes	1	9	8
67	B:B:W332	B:B:Y59	30.9544	3.86	Yes	Yes	1	9	8
68	A:A:F212	A:A:I375	35.608	5.02	Yes	No	0	9	9
69	A:A:F290	A:A:I375	10.1385	5.02	Yes	No	7	9	9
70	A:A:W234	B:B:Y145	12.2309	4.82	Yes	Yes	1	9	8
71	A:A:V287	A:A:W277	19.8738	4.9	No	Yes	0	6	6
72	A:A:F273	A:A:V287	19.1858	9.18	Yes	No	0	9	6
73	A:A:F363	A:A:R342	12.9378	7.48	Yes	Yes	8	5	4
74	A:A:R283	A:A:T284	28.1329	1.29	Yes	No	0	3	4
75	A:A:R389	A:A:T284	27.9757	1.29	No	No	0	4	4
76	A:A:L394	A:A:R389	27.6908	3.64	No	No	0	8	4
77	A:A:L394	A:A:R385	26.7059	4.86	No	Yes	0	8	5
78	A:A:R385	A:A:Y360	25.6667	4.12	Yes	Yes	22	5	8
79	A:A:I288	A:A:I375	24.9191	5.89	Yes	No	7	9	9
80	A:A:D378	A:A:I288	24.788	11.2	No	Yes	0	7	9
81	A:A:F363	A:A:K338	10.1505	18.61	Yes	No	8	5	5
82	A:A:R380	R:R:F719	11.1646	4.28	No	Yes	0	7	9
83	A:A:Q384	A:A:R380	10.5855	4.67	No	No	26	6	7
84	A:A:Q384	R:R:Q803	10.3289	7.68	No	No	0	6	9
85	A:A:Q390	R:R:D651	26.0142	10.44	No	No	0	4	9
86	B:B:H62	B:B:Y105	90.8697	4.36	No	Yes	0	6	6
87	B:B:H62	B:B:R150	90.623	12.41	No	No	0	6	6
88	B:B:L190	B:B:R150	69.6139	3.64	No	No	31	5	6
89	B:B:L190	B:B:S160	72.382	9.01	No	No	0	5	6
90	B:B:S160	B:B:V187	72.1075	3.23	No	No	0	6	9
91	B:B:H183	B:B:V187	71.5133	4.15	Yes	No	6	9	9
92	B:B:H183	B:B:K209	58.665	18.34	Yes	Yes	6	9	6
93	B:B:K209	B:B:T221	52.6138	13.51	Yes	No	0	6	7
94	B:B:T221	G:G:E22	52.3193	8.47	No	No	0	7	1
95	B:B:I18	G:G:E22	52.0265	5.47	No	No	0	7	1
96	B:B:I18	B:B:R22	44.2921	5.01	No	No	0	7	6
97	B:B:D258	B:B:R22	12.7934	7.15	Yes	No	0	7	6
98	B:B:Q259	B:B:R22	32.9472	4.67	Yes	No	0	6	6
99	B:B:Q259	G:G:V30	31.9836	7.16	Yes	No	0	6	8
100	B:B:L261	G:G:V30	31.3392	4.47	No	No	0	5	8
101	B:B:L261	B:B:L30	31.0164	8.3	No	No	0	5	5
102	B:B:L30	B:B:M262	23.4839	4.24	No	Yes	0	5	4
103	R:R:D651	R:R:S654	25.7956	7.36	No	No	0	9	9
104	R:R:S654	R:R:Y642	25.5776	3.82	No	Yes	0	9	9
105	R:R:I648	R:R:Y642	17.7685	9.67	Yes	Yes	0	8	9
106	R:R:I648	R:R:Q881	13.6758	4.12	Yes	No	0	8	9
107	R:R:K647	R:R:Q881	12.8287	5.42	No	No	0	9	9
108	B:B:D312	R:R:K647	12.5454	15.21	No	No	0	5	9
109	B:B:D312	B:B:D333	12.2628	11.98	No	Yes	0	5	9
110	B:B:C148	B:B:R150	20.7619	6.96	No	No	31	6	6
111	B:B:C148	B:B:T102	23.4672	3.38	No	No	0	6	8
112	B:B:C149	B:B:T102	23.1299	5.07	No	No	0	8	8
113	B:B:C121	B:B:C149	14.3828	3.64	No	No	0	8	8
114	B:B:C121	B:B:L139	14.0398	6.35	No	Yes	0	8	9
115	B:B:H183	B:B:W211	11.2081	6.35	Yes	Yes	6	9	8
116	B:B:C218	G:G:Q18	12.3225	9.16	No	No	0	5	9
117	G:G:M21	G:G:Q18	11.6673	4.08	No	No	0	2	9
118	B:B:M217	G:G:M21	11.0502	4.33	No	No	0	3	2
119	B:B:M262	B:B:Y264	19.8081	8.38	Yes	Yes	0	4	5
120	B:B:L252	B:B:Y264	12.3139	5.86	No	Yes	0	7	5
121	B:B:F278	B:B:L252	11.9687	2.44	Yes	No	0	7	7
122	R:R:H710	R:R:I656	27.7958	7.95	Yes	Yes	0	9	9
123	R:R:E707	R:R:I656	38.9246	13.66	No	Yes	0	9	9
124	R:R:E707	R:R:L833	38.5885	6.63	No	No	0	9	9
125	R:R:L660	R:R:L833	26.5391	2.77	No	No	0	9	9
126	R:R:L660	R:R:L664	26.1587	2.77	No	No	0	9	9
127	R:R:L664	R:R:Q863	25.4052	5.32	No	Yes	0	9	9
128	R:R:Q863	R:R:W838	23.9286	4.38	Yes	Yes	2	9	9
129	L:L:?1	R:R:W838	22.3295	5.67	Yes	Yes	2	0	9
130	R:R:F730	R:R:Y726	31.71	13.41	Yes	Yes	0	8	8
131	R:R:F730	R:R:I656	25	3.77	Yes	Yes	0	8	9
132	L:L:?1	R:R:F671	18.8872	18.17	Yes	No	2	0	9
133	R:R:L833	R:R:Y871	12.4033	16.41	No	No	0	9	8
134	R:R:G829	R:R:Y871	11.8286	4.35	No	No	0	9	8
135	R:R:F870	R:R:G829	11.3545	4.52	Yes	No	0	9	9
136	R:R:F870	R:R:I869	10.0412	3.77	Yes	No	0	9	6
137	R:R:I656	R:R:W703	16.5399	4.7	Yes	Yes	0	9	9
138	R:R:F671	R:R:L693	10.9389	4.87	No	Yes	2	9	9
139	R:R:D674	R:R:V689	11.9593	13.15	Yes	No	0	9	8
140	R:R:G734	R:R:W703	14.2265	7.04	No	Yes	0	9	9
141	R:R:G734	R:R:T702	13.6607	3.64	No	No	0	9	9
142	R:R:T702	R:R:Y785	12.0076	6.24	No	No	0	9	9
143	R:R:L698	R:R:Y785	11.4397	4.69	No	No	0	9	9
144	R:R:H694	R:R:L698	10.8714	9	Yes	No	0	9	9
145	R:R:F786	R:R:W838	10.084	8.02	No	Yes	2	9	9
146	R:R:F786	R:R:F842	10.1774	7.5	No	No	0	9	9
147	R:R:Q803	R:R:R806	10.0543	10.51	No	No	0	9	9
148	A:A:D378	A:A:Y360	25.8109	16.09	No	Yes	0	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:T624	10.26	2	Yes	No	0	9	0	1
L:L:?1	R:R:L667	9.64	2	Yes	No	0	9	0	1
L:L:?1	R:R:N668	5.46	2	Yes	No	0	9	0	1
L:L:?1	R:R:F671	18.17	2	Yes	No	0	9	0	1
L:L:?1	R:R:W838	5.67	2	Yes	Yes	0	9	0	1
L:L:?1	R:R:F856	21.81	2	Yes	Yes	0	9	0	1
L:L:?1	R:R:T861	4.4	2	Yes	No	0	8	0	1
R:R:C628	R:R:L672	4.76	0	No	No	9	9	1	2
R:R:N668	R:R:S631	7.45	0	No	No	9	9	1	2
R:R:F671	R:R:L693	4.87	2	No	Yes	9	9	1	2
R:R:F671	R:R:F769	4.29	2	No	No	9	9	1	2
R:R:F769	R:R:L693	3.65	2	No	Yes	9	9	2	2
R:R:F701	R:R:F786	15	2	No	No	9	9	2	2
R:R:F701	R:R:W838	14.03	2	No	Yes	9	9	2	1
R:R:G835	R:R:M704	3.49	2	No	No	9	9	2	2
R:R:M704	R:R:W838	5.82	2	No	Yes	9	9	2	1
R:R:M704	R:R:Q863	4.08	2	No	Yes	9	9	2	2
R:R:F786	R:R:W838	8.02	2	No	Yes	9	9	2	1
R:R:G835	R:R:W838	4.22	2	No	Yes	9	9	2	1
R:R:F856	R:R:W838	5.01	2	Yes	Yes	9	9	1	1
R:R:N860	R:R:W838	19.21	2	No	Yes	9	9	2	1
R:R:Q863	R:R:W838	4.38	2	Yes	Yes	9	9	2	1
R:R:A841	R:R:F856	8.32	0	No	Yes	9	9	2	1
R:R:A844	R:R:F856	4.16	0	No	Yes	9	9	2	1
R:R:F856	R:R:N860	8.46	2	Yes	No	9	9	1	2
L:L:?1	R:R:C628	3.16	2	Yes	No	0	9	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
45.45	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
41.67	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
37.50	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
37.50	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
35.29	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
35.29	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
33.33	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
31.25	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
29.41	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
29.41	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
28.57	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
27.78	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
27.27	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
26.67	Single	6IIV	Daltroban	6IIV-TXA2-Daltroban
26.67	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
25.00	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
25.00	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
25.00	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
25.00	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
23.53	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
23.53	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
23.53	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
23.53	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
23.08	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
23.08	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
23.08	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
22.22	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
22.22	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
22.22	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
22.22	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
21.74	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
21.74	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
21.43	Single	5U09	Taranabant	5U09-CB₁-Taranabant
21.43	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
21.43	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
21.43	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
21.05	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
21.05	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
21.05	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
21.05	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
21.05	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
20.00	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
20.00	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
20.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
20.00	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
20.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
20.00	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
20.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
20.00	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
20.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
19.23	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
19.23	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
19.23	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
19.05	Single	7QA8	Peptide	7QA8-STE2-Peptide
19.05	Single	7QA8	Peptide	7QA8-STE2-Peptide
18.75	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
18.75	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
18.75	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
18.75	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
18.52	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
18.18	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
18.18	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
18.18	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
18.18	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
17.86	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
17.86	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
17.65	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
17.65	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
17.65	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
17.65	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
17.65	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
17.65	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
17.65	Consensus	blt_off	Orthosteric Ligand	blt1_off
17.65	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
17.24	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
16.67	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
16.67	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
16.67	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
16.67	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
16.67	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
16.67	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
16.67	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
16.67	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
16.67	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
16.67	Consensus	sensory_on	Orthosteric Ligand	opsins_on
16.13	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
16.00	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
16.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
16.00	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
16.00	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
16.00	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
16.00	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
16.00	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
15.79	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
15.79	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
15.79	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
15.79	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
15.79	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
15.79	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
15.79	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
15.79	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
15.62	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
15.38	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
15.38	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
15.38	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
15.38	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
15.38	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
15.38	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
15.38	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
15.38	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
15.38	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
15.38	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
15.38	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
15.38	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
15.38	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
15.38	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
15.38	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
15.38	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
15.38	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
15.38	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
15.38	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
15.38	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
15.38	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
15.38	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
15.38	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
15.38	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
15.38	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
15.38	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
15.38	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
15.38	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
15.00	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
15.00	Single	5X93	K-8794	5X93-ET_B-K-8794
15.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
15.00	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
15.00	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
15.00	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
15.00	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
15.00	Single	9CGJ	C6-Quino	9CGJ-δ-C6-Quino-Gi1/β1/γ2
15.00	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
15.00	Consensus	endothelin_off	Orthosteric Ligand	etb_off
15.00	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
14.81	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
14.81	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
14.81	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
14.81	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
14.81	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
14.81	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
14.81	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
14.81	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
14.29	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
14.29	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
14.29	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
14.29	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
14.29	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
14.29	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
14.29	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
14.29	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
14.29	Single	6LI0	C17	6LI0-GPR52-C17
14.29	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
14.29	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
14.29	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
14.29	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
14.29	Single	6PT3	DPI-287	6PT3-δ-DPI-287
14.29	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
14.29	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
14.29	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
14.29	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
14.29	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
14.29	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
14.29	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
14.29	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
14.29	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
14.29	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
14.29	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
14.29	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
14.29	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
14.29	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
14.29	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
14.29	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
14.29	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
14.29	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
14.29	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
13.64	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
13.33	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
13.33	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
13.33	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
13.33	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
13.33	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
13.33	Single	6B73	MP1104	6B73-κ-MP1104
13.33	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
13.33	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
13.33	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
13.33	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
13.33	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
13.33	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
13.33	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
13.33	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
13.33	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
13.33	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
13.33	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
13.33	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
13.33	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
13.33	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
13.33	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
13.33	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
13.33	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
13.33	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
13.33	Single	9K6L	SA0	9K6L-TAS2R16-SA0-Gi2/β1/γ2
13.33	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
13.33	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
13.33	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
13.33	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
13.33	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
13.33	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
13.33	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
13.33	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
13.33	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
13.33	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
13.16	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
13.04	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
13.04	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
13.04	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
12.90	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
12.90	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
12.90	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
12.90	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
12.90	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
12.50	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
12.50	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
12.50	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
12.50	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
12.50	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
12.50	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
12.50	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
12.50	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
12.50	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
12.50	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
12.50	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
12.50	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
12.50	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
12.50	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
12.50	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
12.50	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
12.50	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
12.50	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
12.50	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
12.50	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
12.50	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
12.50	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
12.50	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
12.50	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
12.50	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
12.50	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
12.50	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
12.50	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
12.50	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
12.50	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
12.50	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
12.50	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
12.50	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
12.50	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
12.50	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
12.50	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
12.50	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
12.50	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
12.50	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Single	9LRD	Histamine	9LRD-H₁-Histamine-Gi1/β1/γ2
12.50	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
12.50	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
12.50	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
12.50	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
12.50	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
12.50	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
12.50	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
12.50	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
12.50	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
12.50	Consensus	sensory_off	Orthosteric Ligand	opsins_off
12.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
12.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
12.00	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
12.00	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
12.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
12.00	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
11.76	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
11.76	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
11.76	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
11.76	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
11.76	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
11.76	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
11.76	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
11.76	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
11.76	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
11.76	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
11.76	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
11.76	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
11.76	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
11.76	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
11.76	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
11.76	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
11.76	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
11.76	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
11.76	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
11.76	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
11.76	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
11.76	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
11.76	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
11.76	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.76	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
11.76	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
11.76	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
11.76	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
11.76	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
11.76	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8JXR	LSD	8JXR-D₁-LSD
11.76	Single	8T1W	CVN424	8T1W-GPR6-CVN424
11.76	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
11.76	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
11.76	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
11.76	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
11.76	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
11.76	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
11.76	Single	9JEA	Atropine	9JEA-M₁-Atropine
11.76	Single	9KFJ	PubChem 138319674	9KFJ-RXFP3-PubChem 138319674-Gi2/β1/γ2
11.76	Single	9PLN	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLN-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine
11.76	Single	9PLO	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLO-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine-Go/β1/γ2
11.76	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
11.76	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
11.76	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
11.76	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
11.76	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
11.76	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
11.76	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
11.76	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
11.76	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
11.76	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.76	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.76	Consensus	blt_on	Orthosteric Ligand	blt1_on
11.76	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
11.76	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
11.76	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
11.76	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
11.76	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
11.76	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.76	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
11.76	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
11.76	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
11.76	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
11.76	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
11.76	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
11.76	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
11.76	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
11.76	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
11.54	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
11.54	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
11.54	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
11.54	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
11.54	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
11.54	Consensus	pac_on	Orthosteric Ligand	pac1_on
11.54	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
11.43	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
11.11	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
11.11	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
11.11	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
11.11	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
11.11	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
11.11	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-Cmpd-15
11.11	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
11.11	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
11.11	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
11.11	Single	6FJ3	PTH	6FJ3-PTH1-PTH
11.11	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
11.11	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
11.11	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
11.11	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
11.11	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
11.11	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
11.11	Single	6PS6	Timolol	6PS6-β₂-Timolol
11.11	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
11.11	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
11.11	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
11.11	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
11.11	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
11.11	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
11.11	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
11.11	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
11.11	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
11.11	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
11.11	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
11.11	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
11.11	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
11.11	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
11.11	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
11.11	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
11.11	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
11.11	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
11.11	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
11.11	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
11.11	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
11.11	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
11.11	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
11.11	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
11.11	Single	9DYD	Asenapine	9DYD-5-HT_1A-Asenapine-Go/β1/γ2
11.11	Single	9DYF	Asenapine	9DYF-5-HT_1A-Asenapine-Gi1/β1/γ2
11.11	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
11.11	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
11.11	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go/β1/γ2
11.11	Single	9HC0	4YI	9HC0-mGlu₅-4YI
11.11	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
11.11	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
11.11	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
11.11	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
11.11	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
11.11	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
11.11	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
11.11	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
11.11	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
11.11	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
11.11	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
11.11	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
11.11	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
11.11	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
11.11	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
11.11	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
11.11	Consensus	ep_off	Orthosteric Ligand	ep4_off
11.11	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
11.11	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
11.11	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
11.11	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
11.11	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
11.11	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
11.11	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
11.11	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
11.11	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
10.81	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
10.71	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
10.71	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
10.71	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
10.71	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
10.71	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
10.71	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
10.71	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
10.71	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
10.71	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
10.71	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
10.53	Single	2YDV	NECA	2YDV-A_2A-NECA
10.53	Single	4DJH	JDTic	4DJH-κ-JDTic
10.53	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
10.53	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
10.53	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
10.53	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
10.53	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
10.53	Single	5G53	NECA	5G53-A_2A-NECA-Gs
10.53	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
10.53	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
10.53	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
10.53	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
10.53	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
10.53	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
10.53	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
10.53	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
10.53	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
10.53	Single	7P2L	4YI	7P2L-mGlu₅-4YI
10.53	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
10.53	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
10.53	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
10.53	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
10.53	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
10.53	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
10.53	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
10.53	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
10.53	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
10.53	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
10.53	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
10.53	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
10.53	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
10.53	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
10.53	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
10.53	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
10.53	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
10.53	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
10.53	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
10.53	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
10.53	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
10.53	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
10.53	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
10.53	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
10.53	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
10.53	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
10.53	Consensus	a2_on	Orthosteric Ligand	a2b_on
10.53	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
10.53	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.53	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.53	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
10.53	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
10.53	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
10.53	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
10.53	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
10.53	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
10.53	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
10.53	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
10.53	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
10.53	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
10.53	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.53	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
10.53	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
10.34	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
10.34	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
10.34	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
10.34	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
10.34	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
10.34	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
10.34	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
10.00	Single	3D4S	Timolol	3D4S-β₂-Timolol
10.00	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
10.00	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
10.00	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
10.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
10.00	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
10.00	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
10.00	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
10.00	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
10.00	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
10.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
10.00	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
10.00	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
10.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
10.00	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
10.00	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.00	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
10.00	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
10.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
10.00	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
10.00	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
10.00	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
10.00	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
10.00	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
10.00	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
10.00	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
10.00	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
10.00	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
10.00	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
10.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
10.00	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
10.00	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
10.00	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
10.00	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
10.00	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
10.00	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
10.00	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
10.00	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
10.00	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
10.00	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
10.00	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
9.68	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
9.68	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
9.68	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
9.68	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
9.52	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
9.52	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
9.52	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
9.52	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
9.52	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
9.52	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
9.52	Single	7EZC	UKA	7EZC-A_2A-UKA
9.52	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
9.52	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
9.52	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
9.52	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
9.52	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
9.52	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
9.52	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
9.52	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
9.52	Single	8S2T	Isoprenaline	8S2T-β₁-Isoprenaline-chim(NtGi1-Gs)/β1/γ2
9.52	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.52	Single	9AS0	2-bromo-LSD	9AS0-5-HT_2A-2-bromo-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	9DYE	Buspirone	9DYE-5-HT_1A-Buspirone-Go/β1/γ2
9.52	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
9.52	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
9.52	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
9.38	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
9.38	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
9.38	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
9.38	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
9.09	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
9.09	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
9.09	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
9.09	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
9.09	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
9.09	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
9.09	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
9.09	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
9.09	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
9.09	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
8.82	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
8.82	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
8.70	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
8.70	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
8.70	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
8.70	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
8.70	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
8.70	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
8.70	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
8.70	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
8.70	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
8.70	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
8.70	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-Gi1/β1/γ1
8.70	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
8.70	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
8.70	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.70	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
8.70	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
8.70	Single	9M4T	Silodosin	9M4T-Alpha1A-Silodosin
8.70	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.70	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
8.70	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
8.33	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
8.33	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
8.33	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
8.33	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
8.33	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
8.33	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
8.33	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
8.33	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
8.33	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
8.00	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
8.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
8.00	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
8.00	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
8.00	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
8.00	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
8.00	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
8.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
8.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
7.69	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
7.69	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
7.69	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
7.69	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
7.69	Single	7MTB	All-trans-Retinal	7MTB-Rhodopsin-All-trans-Retinal-GRK1
7.69	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
7.69	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
7.69	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
7.69	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
7.69	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
7.69	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
7.69	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8Y02	Retinal	8Y02-OPN1SW-Retinal-Gi1/β1/γ2
7.69	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
7.69	Single	9EE9	Adenosine	9EE9-A_2A-Adenosine-Gs/β1/γ2
7.69	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
7.69	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
7.69	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
7.41	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
7.41	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
7.41	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
7.41	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
7.41	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
7.41	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
7.41	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
7.41	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
7.14	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
7.14	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
7.14	Single	6FUF	All-trans-Retinal	6FUF-Rhodopsin-All-trans-Retinal-Go
7.14	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
7.14	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
7.14	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
7.14	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
7.14	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
7.14	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
7.14	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
7.14	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
7.14	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
7.14	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
7.14	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
7.14	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
7.14	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
7.14	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
7.14	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
7.14	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
7.14	Single	9LRC	Histamine	9LRC-H₄-Histamine
7.14	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
7.14	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
7.14	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
7.14	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
7.14	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
6.90	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
6.90	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
6.90	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
6.90	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
6.90	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
6.67	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
6.67	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
6.67	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
6.67	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
6.67	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.67	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
6.67	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
6.67	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
6.67	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
6.67	Single	7XP6	Strychnine	7XP6-TAS2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
6.67	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
6.67	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
6.67	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
6.67	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
6.67	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
6.67	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
6.67	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
6.67	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
6.67	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
6.67	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
6.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
6.67	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
6.67	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
6.67	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
6.67	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
6.67	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
6.67	Single	9AS2	DMT	9AS2-5-HT_2A-DMT-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	9B9Y	7DY	9B9Y-CB₁-7DY
6.67	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
6.67	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
6.67	Single	9IXJ	Histamine	9IXJ-H₂-Histamine-Gs/β1/γ2
6.67	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
6.67	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
6.67	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
6.67	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
6.67	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
6.67	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
6.45	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
6.25	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
6.25	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
6.25	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
6.25	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
6.25	Single	4XNV	BPTU	4XNV-P2Y₁-BPTU
6.25	Single	5WS3	EMPA	5WS3-OX₂-EMPA
6.25	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
6.25	Single	6AKX	A4R	6AKX-CCR5-A4R
6.25	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
6.25	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
6.25	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
6.25	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
6.25	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
6.25	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
6.25	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
6.25	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
6.25	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
6.25	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
6.25	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
6.25	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
6.25	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
6.25	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.25	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.25	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.25	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.25	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
6.25	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
6.25	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
6.25	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
6.25	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
6.25	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
6.25	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
6.25	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
6.25	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
6.25	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
6.25	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
6.25	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
6.25	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
6.25	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
6.25	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
6.25	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
6.25	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
6.25	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
6.25	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
6.25	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
6.25	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
6.25	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
6.25	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
6.25	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
6.25	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
6.25	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
6.25	Single	9H2X	A1IR1	9H2X-A_2A-A1IR1-Na
6.25	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
6.25	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
6.25	Single	9LRB	Histamine	9LRB-H₁-Histamine-Gs/β1/γ2
6.25	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
6.25	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
6.25	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
6.25	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
6.25	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
6.25	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
6.25	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
6.25	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
6.25	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
6.25	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
6.25	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
6.06	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
5.88	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
5.88	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
5.88	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
5.88	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
5.88	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
5.88	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
5.88	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
5.88	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
5.88	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
5.88	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
5.88	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
5.88	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
5.88	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
5.88	Single	6IQL	L745870	6IQL-D₄-L745870
5.88	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
5.88	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
5.88	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
5.88	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
5.88	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
5.88	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
5.88	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
5.88	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
5.88	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
5.88	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
5.88	Single	6TPG	EMPA	6TPG-OX₂-EMPA
5.88	Single	6TPK	Retosiban	6TPK-OT-Retosiban
5.88	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
5.88	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
5.88	Single	6VI4	JDTic	6VI4-κ-JDTic
5.88	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
5.88	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
5.88	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
5.88	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
5.88	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.88	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.88	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
5.88	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
5.88	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
5.88	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
5.88	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
5.88	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.88	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
5.88	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
5.88	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
5.88	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.88	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
5.88	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
5.88	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
5.88	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
5.88	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
5.88	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.88	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
5.88	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
5.88	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
5.88	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
5.88	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
5.88	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
5.88	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
5.88	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
5.88	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
5.88	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
5.88	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
5.88	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.88	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
5.88	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
5.88	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
5.88	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
5.88	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
5.88	Single	9AS3	LSD	9AS3-5-HT_2A-LSD
5.88	Single	9AS4	LSD	9AS4-5-HT_2A-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AS5	Mescaline	9AS5-5-HT_2A-Mescaline
5.88	Single	9AS6	Mescaline	9AS6-5-HT_2A-Mescaline-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
5.88	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
5.88	Single	9KPD	SA0	9KPD-TAS2R16-SA0-chim(Gs-CtGt3)/β1/γ2
5.88	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
5.88	Consensus	a2_off	Orthosteric Ligand	a2a_off
5.88	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
5.88	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
5.88	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
5.88	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.88	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.88	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.88	Consensus	hca_on	Orthosteric Ligand	hca2_on
5.88	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
5.88	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
5.88	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
5.71	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
5.56	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
5.56	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
5.56	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
5.56	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
5.56	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
5.56	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
5.56	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
5.56	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
5.56	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
5.56	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
5.56	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
5.56	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
5.56	Single	4QKX	35V	4QKX-β₂-35V
5.56	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
5.56	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
5.56	Single	5DHG	C-35	5DHG-NOP-C-35
5.56	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
5.56	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
5.56	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
5.56	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
5.56	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
5.56	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
5.56	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
5.56	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
5.56	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
5.56	Single	6GPS	MK0812	6GPS-CCR2-MK0812
5.56	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
5.56	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
5.56	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
5.56	Single	6PS1	Timolol	6PS1-β₂-Timolol
5.56	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
5.56	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
5.56	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
5.56	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
5.56	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
5.56	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
5.56	Single	7BU7	BI167107	7BU7-β₁-BI167107
5.56	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
5.56	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
5.56	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.56	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
5.56	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
5.56	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
5.56	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
5.56	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.56	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
5.56	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
5.56	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
5.56	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
5.56	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
5.56	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
5.56	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
5.56	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
5.56	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.56	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
5.56	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
5.56	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
5.56	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
5.56	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
5.56	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
5.56	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
5.56	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
5.56	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
5.56	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
5.56	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
5.56	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
5.56	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
5.56	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.56	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.56	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
5.56	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
5.56	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.56	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.56	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
5.56	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
5.56	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
5.56	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-Gi1/β1/γ1
5.56	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
5.56	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
5.56	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
5.56	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
5.56	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
5.56	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
5.56	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
5.56	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
5.56	Single	9AS1	DMT	9AS1-5-HT_2A-DMT
5.56	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
5.56	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
5.56	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
5.56	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
5.56	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
5.56	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
5.56	Single	9PQD	(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole	9PQD-α_2a-(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole
5.56	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
5.56	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.56	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.56	Consensus	a3_on	Orthosteric Ligand	a3a_on
5.56	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
5.56	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
5.56	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
5.56	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.56	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
5.56	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
5.56	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.56	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
5.56	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.56	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
5.56	Consensus	histamine_off	Orthosteric Ligand	h1_off
5.56	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.56	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.26	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
5.26	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
5.26	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
5.26	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
5.26	Single	5C1M	BU72	5C1M-μ-BU72
5.26	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
5.26	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
5.26	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
5.26	Single	5N2S	PSB36	5N2S-A₁-PSB36
5.26	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
5.26	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
5.26	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
5.26	Single	5WQC	EMPA	5WQC-OX₂-EMPA
5.26	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
5.26	Single	6GPX	MK0812	6GPX-CCR2-MK0812
5.26	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
5.26	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
5.26	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
5.26	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
5.26	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
5.26	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
5.26	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
5.26	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
5.26	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
5.26	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
5.26	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
5.26	Single	7C4S	S1P	7C4S-S1P₃-S1P
5.26	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
5.26	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
5.26	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
5.26	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
5.26	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
5.26	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
5.26	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
5.26	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
5.26	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.26	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
5.26	Single	7W41	PD176252	7W41-BB₂-PD176252
5.26	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
5.26	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
5.26	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
5.26	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
5.26	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
5.26	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
5.26	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
5.26	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
5.26	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
5.26	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
5.26	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.26	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
5.26	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
5.26	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
5.26	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
5.26	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
5.26	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.26	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.26	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
5.26	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
5.26	Single	9ARZ	2-bromo-LSD	9ARZ-5-HT_2A-2-bromo-LSD
5.26	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
5.26	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
5.26	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
5.26	Single	9HAP	Tolvaptan	9HAP-V₂-Tolvaptan
5.26	Single	9K07	DSO-5a	9K07-BB₃-DSO-5a-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
5.26	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.26	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
5.26	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
5.26	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.26	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.26	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
5.26	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
5.26	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
5.26	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
5.26	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
5.26	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
5.26	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
5.26	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.26	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.26	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.26	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.26	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
5.26	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
5.26	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
5.26	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
5.26	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.26	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.13	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
5.00	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
5.00	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
5.00	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
5.00	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
5.00	Single	5V56	TC114	5V56-SMO-TC114
5.00	Single	5V57	TC114	5V57-SMO-TC114
5.00	Single	5XR8	AM841	5XR8-CB₁-AM841
5.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.00	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.00	Single	6E59	L-760735	6E59-NK₁-L-760735
5.00	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
5.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
5.00	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
5.00	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
5.00	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
5.00	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
5.00	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
5.00	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.00	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
5.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
5.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
5.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
5.00	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
5.00	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
5.00	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
5.00	Single	8E0G	BU72	8E0G-μ-BU72
5.00	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
5.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
5.00	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
5.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
5.00	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
5.00	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
5.00	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
5.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
5.00	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.00	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
5.00	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
5.00	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
5.00	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
5.00	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
5.00	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
5.00	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
5.00	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.00	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
5.00	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
5.00	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
5.00	Single	9EGO	YVF	9EGO-CB₁-YVF-Gi1/β1/γ2
5.00	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
5.00	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
5.00	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
5.00	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
5.00	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.00	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.00	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
5.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
5.00	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.00	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
5.00	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.00	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
5.00	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
5.00	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
5.00	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
4.76	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
4.76	Single	4LDE	BI167107	4LDE-β₂-BI167107
4.76	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.76	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
4.76	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
4.76	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
4.76	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
4.76	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
4.76	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.76	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
4.76	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
4.76	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
4.76	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
4.76	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.76	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.76	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
4.76	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
4.76	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
4.76	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
4.76	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
4.76	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
4.76	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
4.76	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
4.76	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
4.76	Single	8JD3	JNJ-40411813	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
4.76	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
4.76	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
4.76	Single	8JWY	2-118	8JWY-A_2A-2-118
4.76	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
4.76	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
4.76	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.76	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
4.76	Single	9DGI	Z8526711350	9DGI-CB₁-Z8526711350
4.76	Single	9GL2	Befiradol	9GL2-5-HT_1A-Befiradol-Gs/β1/γ2
4.76	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.76	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.76	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
4.76	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
4.76	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.76	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.76	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
4.76	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
4.76	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
4.76	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
4.76	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.76	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.76	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.76	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
4.76	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
4.76	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
4.76	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
4.76	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.76	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.76	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.76	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.76	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.55	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
4.55	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
4.55	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
4.55	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
4.55	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
4.55	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
4.55	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
4.55	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
4.55	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
4.55	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
4.55	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
4.55	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
4.55	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
4.55	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
4.55	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
4.55	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
4.55	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
4.55	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
4.55	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
4.55	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
4.55	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
4.55	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.55	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.55	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.55	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
4.55	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.55	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
4.55	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
4.55	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
4.35	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
4.35	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
4.35	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
4.35	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
4.35	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.35	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
4.35	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
4.35	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
4.35	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
4.35	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
4.35	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
4.35	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.35	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
4.35	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
4.35	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
4.35	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
4.35	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
4.35	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.35	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
4.35	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
4.35	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
4.35	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
4.35	Single	9IZA	SCH900271	9IZA-HCA₂-SCH900271-Gi1/β1/γ2
4.35	Single	9JF4	PD168368	9JF4-BB₁-PD168368
4.35	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
4.35	Single	9MD1	Buspirone	9MD1-5-HT_1A-Buspirone-Gz/β1/γ2
4.35	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
4.35	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
4.35	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
4.35	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
4.35	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.35	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.17	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
4.17	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
4.17	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
4.17	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
4.17	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
4.17	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
4.17	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
4.17	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
4.17	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
4.17	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
4.17	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
4.17	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
4.17	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.17	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.17	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
4.17	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
4.17	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
4.17	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
4.17	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
4.17	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
4.17	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
4.17	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
4.17	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.17	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
4.00	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
4.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
4.00	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
4.00	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
4.00	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
4.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
4.00	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
4.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
4.00	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
4.00	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
4.00	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
4.00	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
4.00	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
4.00	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
4.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
4.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
4.00	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.00	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.00	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
4.00	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
3.85	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
3.85	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
3.85	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
3.85	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
3.85	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.85	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
3.85	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
3.85	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
3.85	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.85	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
3.85	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.85	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.85	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
3.85	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
3.85	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
3.85	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.85	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
3.85	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
3.70	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
3.70	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
3.70	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
3.70	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
3.70	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
3.70	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.70	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.70	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
3.70	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
3.70	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
3.70	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
3.57	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
3.57	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
3.57	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
3.57	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
3.57	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.57	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
3.57	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
3.57	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
3.57	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
3.57	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.57	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
3.57	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
3.57	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.45	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
3.45	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.45	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
3.45	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
3.45	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.45	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
3.33	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
3.33	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
3.33	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
3.33	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
3.33	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
3.33	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
3.33	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
3.33	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
3.33	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
3.33	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.23	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
3.23	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
3.23	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.23	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.23	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.23	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
3.23	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
3.23	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.23	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
3.23	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.23	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.23	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
3.12	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
3.12	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
3.12	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
3.12	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
3.12	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
3.03	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.03	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
2.94	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
2.94	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
2.86	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
2.63	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2

PDB Summary
PDB	8YKD
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRG2
Species	Mus Musculus
Ligand	Dehydroepiandrosterone
Other Ligand(s)	-
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	2.9
Date	2025-08-13
D.O.I.	doi.org/10.1038/s41589-025-01896-2

Net Summary
I_min	3.42
Number of Linked Nodes	826
Number of Links	996
Number of Hubs	154
Number of Links mediated by Hubs	576
Number of Communities	36
Number of Nodes involved in Communities	258
Number of Links involved in Communities	346

Path Summary
Number Of Nodes in MetaPath	149
Number Of Links MetaPath	148
Number of Shortest Paths	1114478
Length Of Smallest Path	3
Average Path Length	30.9769
Length of Longest Path	67
Minimum Path Strength	1.24
Average Path Strength	7.46528
Maximum Path Strength	21.01
Minimum Path Correlation	0.7
Average Path Correlation	0.974879
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.17391
Average % Of Corr. Nodes	43.2365
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.953
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• peptide hormone receptor binding • protein binding • binding • corticotropin-releasing hormone receptor binding • signaling receptor binding • G protein-coupled receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • mu-type opioid receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • ionotropic glutamate receptor binding • glutamate receptor binding • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • molecular function regulator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • insulin-like growth factor receptor binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • intracellular anatomical structure • cytoplasm • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • developmental process • spermatid development • spermatid differentiation • sexual reproduction • cellular developmental process • spermatogenesis • reproductive process • multicellular organismal reproductive process • cell development • cellular process involved in reproduction in multicellular organism • developmental process involved in reproduction • gamete generation • male gamete generation • cell differentiation • anatomical structure development • germ cell development • cell surface receptor signaling pathway • cytosol • apical part of cell • plasma membrane region • apical plasma membrane • protein binding • binding • G-protein beta-subunit binding • protein-containing complex binding • enzyme binding • GTPase binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • phospholipase C-activating G protein-coupled receptor signaling pathway • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • sensory system development • system development • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle • organelle membrane • synapse • cell junction
SCOP2	Domain Identifier	• WD40 repeat-like
SCOP2	Family Identifier	• WD40 repeat-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	AND
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	AND
Name	Prasterone
Synonyms	Dehydroepiandrosterone
Identifier
Formula	C19 H28 O2
Molecular Weight	288.424
SMILES
PubChem	5881
Formal Charge	0
Total Atoms	49
Total Chiral Atoms	6
Total Bonds	52
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8YKD_Chain_A E K A E K I E K Q L Q K D K Q V Y R A T H R L L L L G A S G K S T I V K Q M R I H S G I F E T K F Q V D K V N F H M F D V G Q R D E R R K W I Q C F N D V T A I I F V V S S Y N R L Q E A L N F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C V D T E N R R F N D C R D I I Q R M H L R Q Y E L L L S A D A V R S M D N Y A D D D S A I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62871
Sequence	>8YKD_Chain_B L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	A0A7J7XNR4
Sequence	>8YKD_Chain_G Q E E S A S I A A R K L V Q L K M A N I D R I K V K A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q8CJ12
Sequence	>8YKD_Chain_R A L T F I T Y I G C G L S S I F L S V T L V T Y I A F E K I R R D Y P S K I L I Q L C A A L L L L N L I F L L D S W I A L Y N T R G F C I A V A V F L H Y F L L V S F T W M G L E A F H M Y L A L V K V F N T Y I R K Y I L K F C I V G W G I P A V V V S I V L T I S P D N Y G I F C W I N S N V V F Y I T V V G Y F C V I F L L N V S M F I V V L V Q L C R I K K K D L R S I A G L T F L L G I T W G F A F F A W G P V N V T F M Y L F A I F N T L Q G F F I F I F Y C A A K E N V R K Q W R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7WUI	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	IP15	-	chim(NtGi1-Gs)/β1/γ2	3.1	2022-04-27	doi.org/10.1038/s41586-022-04590-8
	7WUI (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	IP15	-		3.1	2022-04-27	doi.org/10.1038/s41586-022-04590-8
	7WUQ	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-	Gs/β1/γ2	2.9	2022-04-27	doi.org/10.1038/s41586-022-04590-8
	7WUQ (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-		2.9	2022-04-27	doi.org/10.1038/s41586-022-04590-8
	7XKD	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-	Gs/β1/γ2	2.4	2022-08-10	doi.org/10.1038/s41589-022-01084-6
	7XKD (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-		2.4	2022-08-10	doi.org/10.1038/s41589-022-01084-6
	7XKE	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-08-10	doi.org/10.1038/s41589-022-01084-6
	7XKE (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-		2.9	2022-08-10	doi.org/10.1038/s41589-022-01084-6
	7XKF	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-	Gs/β1/γ2	2.4	2022-08-10	doi.org/10.1038/s41589-022-01084-6
	7XKF (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-		2.4	2022-08-10	doi.org/10.1038/s41589-022-01084-6
	7YP7	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-	Gs/β1/γ2	3.1	2022-08-24	doi.org/10.1038/s41589-022-01084-6
	7YP7 (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-		3.1	2022-08-24	doi.org/10.1038/s41589-022-01084-6
	8YKD	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	Dehydroepiandrosterone	-	chim(NtGi1-Gs)/β1/γ2	2.9	2025-08-13	doi.org/10.1038/s41589-025-01896-2
	8YKD (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	Dehydroepiandrosterone	-		2.9	2025-08-13	doi.org/10.1038/s41589-025-01896-2

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