psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:E16	A:A:R20	4.65	No	No	0	4	3
2	A:A:E16	B:B:T86	8.47	No	Yes	0	4	6
3	A:A:K17	A:A:R20	3.71	No	No	0	4	3
4	A:A:Q19	B:B:D83	10.44	No	Yes	4	4	8
5	A:A:Q19	B:B:T86	7.09	No	Yes	4	4	6
6	A:A:Q19	B:B:N88	13.2	No	No	4	4	7
7	A:A:E27	A:A:N23	9.2	No	No	4	6	7
8	A:A:N23	B:B:N88	12.26	No	No	4	7	7
9	A:A:N23	B:B:K89	6.99	No	Yes	4	7	9
10	A:A:I26	B:B:K89	4.36	No	Yes	0	9	9
11	A:A:E27	B:B:K89	12.15	No	Yes	4	6	9
12	A:A:K32	A:A:Q29	6.78	No	No	0	4	4
13	A:A:D33	A:A:Q29	6.53	No	No	0	5	4
14	A:A:L30	B:B:K78	5.64	No	No	0	5	8
15	A:A:L30	B:B:K89	4.23	No	Yes	0	5	9
16	A:A:Q31	R:R:R724	15.19	No	No	0	4	7
17	A:A:D33	B:B:K78	5.53	No	No	0	5	8
18	A:A:K34	A:A:R38	6.19	No	No	18	4	4
19	A:A:K34	B:B:L55	8.46	No	No	0	4	6
20	A:A:K34	R:R:Y722	9.55	No	No	18	4	6
21	A:A:Q35	R:R:Y722	4.51	No	No	0	3	6
22	A:A:R42	A:A:Y37	19.55	No	No	0	9	4
23	A:A:Y37	B:B:L55	5.86	No	No	0	4	6
24	A:A:R38	R:R:Y722	11.32	No	No	18	4	6
25	A:A:R42	A:A:T40	6.47	No	No	0	9	7
26	A:A:H220	A:A:T40	8.21	No	No	0	7	7
27	A:A:H41	A:A:T242	4.11	No	No	0	6	8
28	A:A:H41	A:A:I383	3.98	No	Yes	5	6	8
29	A:A:H41	R:R:F719	7.92	No	Yes	5	6	9
30	A:A:F222	A:A:R42	5.34	Yes	No	0	7	9
31	A:A:F219	A:A:L43	6.09	Yes	No	0	8	7
32	A:A:F238	A:A:L44	18.27	Yes	No	0	9	9
33	A:A:I244	A:A:L44	5.71	No	No	0	8	9
34	A:A:L45	A:A:N54	4.12	No	No	0	8	9
35	A:A:L45	A:A:M221	9.9	No	No	0	8	8
36	A:A:F246	A:A:L46	6.09	No	No	0	9	8
37	A:A:G47	A:A:N54	5.09	No	No	0	9	9
38	A:A:R265	A:A:S51	13.18	No	No	0	9	9
39	A:A:I56	A:A:K53	10.18	No	No	0	7	9
40	A:A:K293	A:A:K53	8.62	Yes	No	0	9	9
41	A:A:N54	A:A:V247	7.39	No	No	0	9	7
42	A:A:N292	A:A:V57	4.43	No	No	0	9	7
43	A:A:G206	B:B:N119	5.09	No	No	0	8	9
44	A:A:F222	A:A:I207	6.28	Yes	No	2	7	9
45	A:A:I207	B:B:W99	9.4	No	Yes	2	9	9
46	A:A:F208	A:A:G225	4.52	No	No	0	5	9
47	A:A:E209	A:A:F222	4.66	No	Yes	0	9	7
48	A:A:M221	A:A:T210	6.02	No	No	0	8	7
49	A:A:H220	A:A:K211	14.41	No	No	0	7	4
50	A:A:F212	A:A:F219	9.65	No	Yes	0	9	8
51	A:A:F212	A:A:M221	3.73	No	No	0	9	8
52	A:A:N218	A:A:Q213	5.28	No	No	0	4	3
53	A:A:F219	A:A:V214	3.93	Yes	No	0	8	6
54	A:A:R373	A:A:V214	3.92	No	No	0	5	6
55	A:A:F376	A:A:V214	11.8	Yes	No	0	8	6
56	A:A:D215	A:A:R373	10.72	No	No	0	5	5
57	A:A:F219	A:A:V217	5.24	Yes	No	0	8	5
58	A:A:F376	A:A:V217	3.93	Yes	No	5	8	5
59	A:A:V217	R:R:F719	11.8	No	Yes	5	5	9
60	A:A:C379	A:A:F219	5.59	No	Yes	0	8	8
61	A:A:F222	A:A:H220	4.53	Yes	No	0	7	7
62	A:A:F222	B:B:W99	22.05	Yes	Yes	2	7	9
63	A:A:V224	A:A:W234	12.26	No	Yes	0	9	9
64	A:A:Q227	B:B:N119	6.6	No	No	0	9	9
65	A:A:Q227	B:B:Y145	7.89	No	Yes	0	9	8
66	A:A:E230	A:A:R228	11.63	No	Yes	0	9	9
67	A:A:R228	B:B:T164	6.47	Yes	No	0	9	6
68	A:A:R231	A:A:W234	7	No	Yes	0	9	9
69	A:A:L272	A:A:R231	8.5	No	No	0	8	9
70	A:A:K233	A:A:R232	3.71	Yes	No	1	9	8
71	A:A:R232	B:B:C204	5.57	No	Yes	1	8	7
72	A:A:R232	B:B:D228	13.1	No	No	1	8	9
73	A:A:K233	B:B:M188	11.52	Yes	No	0	9	8
74	A:A:K233	B:B:D228	11.06	Yes	No	1	9	9
75	A:A:K233	B:B:N230	4.2	Yes	No	1	9	9
76	A:A:K233	B:B:D246	5.53	Yes	Yes	1	9	9
77	A:A:I235	A:A:W234	4.7	No	Yes	0	9	9
78	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
79	A:A:W234	B:B:Y145	4.82	Yes	Yes	0	9	8
80	A:A:Q236	A:A:W281	9.86	No	Yes	2	8	5
81	A:A:Q236	B:B:R314	4.67	No	Yes	2	8	8
82	A:A:C237	B:B:Y59	5.38	No	No	0	8	8
83	A:A:C237	B:B:M101	4.86	No	Yes	0	8	9
84	A:A:F238	A:A:V241	3.93	Yes	No	0	9	9
85	A:A:F238	B:B:W99	10.02	Yes	Yes	0	9	9
86	A:A:N239	B:B:K57	6.99	No	Yes	2	8	9
87	A:A:N239	B:B:W332	9.04	No	Yes	2	8	9
88	A:A:D240	B:B:K57	6.91	No	Yes	0	6	9
89	A:A:F246	A:A:L272	7.31	No	No	0	9	8
90	A:A:F246	A:A:L289	3.65	No	No	0	9	9
91	A:A:N292	A:A:V247	7.39	No	No	0	9	7
92	A:A:A269	A:A:V248	5.09	No	No	0	9	7
93	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
94	A:A:L297	A:A:S250	6.01	Yes	No	0	8	6
95	A:A:K293	A:A:S251	6.12	Yes	Yes	19	9	9
96	A:A:L296	A:A:S251	7.51	No	Yes	19	6	9
97	A:A:K300	A:A:S251	4.59	No	Yes	0	9	9
98	A:A:N264	A:A:Q267	7.92	No	No	0	9	4
99	A:A:N264	A:A:Y311	20.93	No	No	0	9	6
100	A:A:F312	A:A:L266	7.31	Yes	No	0	8	8
101	A:A:I341	A:A:L266	7.14	No	No	0	8	8
102	A:A:E344	A:A:L270	3.98	Yes	No	0	5	6
103	A:A:F345	A:A:L270	10.96	Yes	No	0	8	6
104	A:A:F273	A:A:W277	4.01	Yes	Yes	20	9	6
105	A:A:F273	A:A:V287	5.24	Yes	No	20	9	6
106	A:A:F273	A:A:F345	8.57	Yes	Yes	0	9	8
107	A:A:F273	A:A:I348	5.02	Yes	No	0	9	4
108	A:A:C359	A:A:F273	4.19	No	Yes	0	5	9
109	A:A:D274	A:A:N278	6.73	No	No	0	5	8
110	A:A:D274	A:A:I348	7	No	No	0	5	4
111	A:A:V287	A:A:W277	4.9	No	Yes	20	6	6
112	A:A:S349	A:A:W277	6.18	No	Yes	0	7	6
113	A:A:S352	A:A:W277	7.41	No	Yes	0	5	6
114	A:A:H357	A:A:W277	28.56	No	Yes	0	7	6
115	A:A:N278	A:A:S352	10.43	No	No	0	8	5
116	A:A:L282	A:A:N279	10.98	No	No	0	9	8
117	A:A:K280	A:A:W281	9.28	No	Yes	2	5	5
118	A:A:K280	A:A:R283	4.95	No	No	0	5	3
119	A:A:K280	B:B:D290	4.15	No	Yes	2	5	6
120	A:A:W281	B:B:D290	10.05	Yes	Yes	2	5	6
121	A:A:W281	B:B:R314	17.99	Yes	Yes	2	5	8
122	A:A:W281	B:B:W332	5.62	Yes	Yes	2	5	9
123	A:A:I382	A:A:S286	9.29	No	No	0	6	8
124	A:A:F290	A:A:I288	3.77	No	No	0	9	9
125	A:A:D378	A:A:I288	13.99	No	No	0	7	9
126	A:A:F345	A:A:L289	10.96	Yes	No	0	8	9
127	A:A:F290	A:A:T364	6.49	No	Yes	17	9	9
128	A:A:F290	A:A:N371	7.25	No	No	17	9	9
129	A:A:F363	A:A:L291	8.53	Yes	No	0	5	8
130	A:A:N292	A:A:T364	7.31	No	Yes	0	9	9
131	A:A:K293	A:A:L296	11.28	Yes	No	19	9	6
132	A:A:K338	A:A:Q294	14.92	No	No	7	5	6
133	A:A:F363	A:A:Q294	8.2	Yes	No	7	5	6
134	A:A:C365	A:A:D295	7.78	No	No	0	8	9
135	A:A:A298	A:A:V334	5.09	No	Yes	0	4	4
136	A:A:D331	A:A:L302	5.43	No	No	0	4	2
137	A:A:D310	A:A:Y311	5.75	No	No	0	3	6
138	A:A:E314	A:A:F312	7	Yes	Yes	16	6	8
139	A:A:F312	A:A:F340	7.5	Yes	Yes	16	8	7
140	A:A:E314	A:A:P313	6.29	Yes	No	0	6	6
141	A:A:E314	A:A:F340	4.66	Yes	Yes	16	6	7
142	A:A:E314	A:A:E344	5.07	Yes	Yes	16	6	5
143	A:A:F315	A:A:R336	17.1	No	No	0	6	5
144	A:A:F315	A:A:F340	17.15	No	Yes	0	6	7
145	A:A:P321	A:A:Y318	5.56	No	Yes	0	5	6
146	A:A:R336	A:A:Y318	4.12	No	Yes	0	5	6
147	A:A:F340	A:A:Y318	12.38	Yes	Yes	0	7	6
148	A:A:D343	A:A:Y318	11.49	No	Yes	0	3	6
149	A:A:R336	A:A:T320	3.88	No	No	0	5	1
150	A:A:P321	A:A:Y339	9.74	No	Yes	0	5	3
151	A:A:E330	A:A:P328	6.29	Yes	No	0	3	1
152	A:A:E330	A:A:V334	11.41	Yes	Yes	0	3	4
153	A:A:D331	A:A:P332	8.05	No	No	0	4	1
154	A:A:D331	A:A:R333	13.1	No	No	0	4	5
155	A:A:K338	A:A:Y339	4.78	No	Yes	7	5	3
156	A:A:F363	A:A:K338	21.09	Yes	No	7	5	5
157	A:A:R342	A:A:Y339	8.23	Yes	Yes	7	4	3
158	A:A:F363	A:A:Y339	8.25	Yes	Yes	7	5	3
159	A:A:E344	A:A:F340	12.83	Yes	Yes	16	5	7
160	A:A:D343	A:A:R342	4.76	No	Yes	0	3	4
161	A:A:L346	A:A:R342	6.07	No	Yes	7	4	4
162	A:A:P361	A:A:R342	7.21	No	Yes	7	5	4
163	A:A:F363	A:A:R342	8.55	Yes	Yes	7	5	4
164	A:A:D343	R:R:L813	4.07	No	No	0	3	8
165	A:A:E344	A:A:R347	9.3	Yes	No	0	5	4
166	A:A:L346	A:A:P361	6.57	No	No	7	4	5
167	A:A:L346	R:R:Q812	9.32	No	No	0	4	8
168	A:A:C359	A:A:S349	6.89	No	No	0	5	7
169	A:A:G353	A:A:S352	3.71	No	No	0	4	5
170	A:A:G353	A:A:R356	4.5	No	No	0	4	2
171	A:A:D354	A:A:G355	6.71	No	No	0	3	2
172	A:A:Y358	A:A:Y360	15.89	No	Yes	8	4	8
173	A:A:R385	A:A:Y358	20.58	Yes	No	8	5	4
174	A:A:Y358	R:R:Q812	18.04	No	No	0	4	8
175	A:A:D378	A:A:Y360	17.24	No	Yes	0	7	8
176	A:A:D381	A:A:Y360	10.34	No	Yes	8	8	8
177	A:A:I382	A:A:Y360	8.46	No	Yes	0	6	8
178	A:A:R385	A:A:Y360	4.12	Yes	Yes	8	5	8
179	A:A:H362	A:A:R374	14.67	No	No	0	9	4
180	A:A:D378	A:A:H362	11.35	No	No	0	7	9
181	A:A:D368	A:A:T364	7.23	No	Yes	17	9	9
182	A:A:N371	A:A:T364	8.77	No	Yes	17	9	9
183	A:A:D368	A:A:E370	3.9	No	No	0	9	4
184	A:A:D368	A:A:N371	8.08	No	No	17	9	9
185	A:A:N377	A:A:R373	7.23	No	No	0	4	5
186	A:A:F376	A:A:N377	4.83	Yes	No	0	8	4
187	A:A:F376	R:R:F719	9.65	Yes	Yes	5	8	9
188	A:A:Q384	A:A:R380	10.51	No	No	5	6	7
189	A:A:R380	R:R:V718	9.15	No	No	5	7	9
190	A:A:D381	A:A:R385	7.15	No	Yes	8	8	5
191	A:A:H387	A:A:I383	3.98	Yes	Yes	0	8	8
192	A:A:I383	R:R:V718	4.61	Yes	No	5	8	9
193	A:A:I383	R:R:F719	3.77	Yes	Yes	5	8	9
194	A:A:Q384	R:R:V718	5.73	No	No	5	6	9
195	A:A:Q384	R:R:Q803	3.84	No	No	0	6	9
196	A:A:R385	A:A:R389	4.26	Yes	No	8	5	4
197	A:A:L394	A:A:R385	4.86	Yes	Yes	8	8	5
198	A:A:R385	R:R:I807	10.02	Yes	No	8	5	8
199	A:A:H387	A:A:M386	6.57	Yes	No	0	8	3
200	A:A:H387	A:A:Q390	3.71	Yes	No	0	8	4
201	A:A:H387	R:R:A714	7.32	Yes	No	0	8	9
202	A:A:L388	A:A:L394	4.15	No	Yes	0	8	8
203	A:A:L388	R:R:L715	5.54	No	No	0	8	8
204	A:A:L394	A:A:R389	3.64	Yes	No	8	8	4
205	A:A:Q390	R:R:D651	6.53	No	No	3	4	9
206	A:A:Q390	R:R:P653	7.9	No	Yes	3	4	9
207	A:A:Y391	R:R:P653	9.74	Yes	Yes	3	4	9
208	A:A:Y391	R:R:E707	6.73	Yes	Yes	3	4	9
209	A:A:Y391	R:R:H710	6.53	Yes	Yes	3	4	9
210	A:A:Y391	R:R:M711	14.37	Yes	No	0	4	9
211	A:A:E392	R:R:R825	11.63	No	No	0	6	9
212	A:A:E392	R:R:K875	6.75	No	No	0	6	9
213	A:A:L393	R:R:L804	4.15	Yes	No	3	8	9
214	A:A:L393	R:R:L830	4.15	Yes	No	0	8	8
215	A:A:L394	R:R:I807	7.14	Yes	No	8	8	8
216	A:A:L394	R:R:R817	7.29	Yes	Yes	0	8	7
217	A:A:L394	R:R:Q822	3.99	Yes	No	0	8	7
218	B:B:L4	B:B:R8	8.5	No	No	0	4	3
219	B:B:L4	G:G:I9	4.28	No	No	0	4	2
220	B:B:L7	B:B:Q6	7.99	No	No	0	8	1
221	B:B:E12	B:B:Q9	7.65	No	No	0	4	3
222	B:B:E10	B:B:Q13	6.37	No	Yes	21	8	1
223	B:B:E10	B:B:L14	7.95	No	Yes	21	8	8
224	B:B:E12	B:B:N16	10.52	No	No	0	4	1
225	B:B:L14	B:B:Q13	5.32	Yes	Yes	21	8	1
226	B:B:Q13	B:B:Q17	3.84	Yes	No	0	1	4
227	B:B:L14	G:G:L19	6.92	Yes	No	0	8	9
228	B:B:K15	G:G:L19	4.23	No	No	0	6	9
229	B:B:N16	B:B:R19	6.03	No	No	0	1	4
230	B:B:I18	B:B:R22	5.01	No	No	0	7	6
231	B:B:A21	G:G:R27	4.15	No	No	0	4	8
232	B:B:D258	B:B:R22	13.1	Yes	No	0	7	6
233	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
234	B:B:D27	G:G:K29	9.68	No	No	0	8	4
235	B:B:D27	G:G:S31	8.83	No	No	0	8	9
236	B:B:S31	B:B:T29	4.8	No	No	0	1	3
237	B:B:Q32	B:B:T29	9.92	No	No	0	1	3
238	B:B:L30	B:B:T34	4.42	Yes	Yes	0	5	5
239	B:B:L261	B:B:L30	4.15	No	Yes	0	5	5
240	B:B:L30	B:B:M262	4.24	Yes	No	0	5	4
241	B:B:L30	G:G:A34	4.73	Yes	No	0	5	6
242	B:B:I33	G:G:A34	6.5	No	No	0	3	6
243	B:B:I37	B:B:T34	4.56	Yes	Yes	6	2	5
244	B:B:L300	B:B:T34	10.32	No	Yes	0	6	5
245	B:B:T34	G:G:M38	6.02	Yes	No	6	5	4
246	B:B:I37	B:B:R283	3.76	Yes	Yes	6	2	9
247	B:B:I37	G:G:M38	5.83	Yes	No	6	2	4
248	B:B:I43	B:B:V40	4.61	No	Yes	0	3	3
249	B:B:R283	B:B:V40	3.92	Yes	Yes	6	9	3
250	B:B:D298	B:B:V40	5.84	Yes	Yes	6	9	3
251	B:B:M45	G:G:L50	7.07	No	No	0	4	9
252	B:B:R46	B:B:R48	9.6	No	No	0	5	7
253	B:B:K337	B:B:T47	9.01	Yes	No	11	6	3
254	B:B:T47	B:B:W339	9.7	No	Yes	11	3	9
255	B:B:N340	B:B:R48	8.44	No	No	0	9	7
256	B:B:R49	G:G:F61	7.48	No	Yes	0	7	8
257	B:B:R52	B:B:T50	10.35	No	No	0	7	3
258	B:B:K337	B:B:T50	7.51	Yes	No	0	6	3
259	B:B:L51	B:B:W82	20.5	No	Yes	0	9	9
260	B:B:L336	B:B:L51	6.92	No	No	0	7	9
261	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
262	B:B:H54	B:B:S72	9.76	Yes	No	4	9	9
263	B:B:H54	B:B:S74	12.55	Yes	No	0	9	9
264	B:B:H54	B:B:I80	13.26	Yes	No	4	9	8
265	B:B:H54	B:B:W82	5.29	Yes	Yes	4	9	9
266	B:B:D76	B:B:L55	12.21	No	No	0	9	6
267	B:B:K57	B:B:Y59	7.17	Yes	No	2	9	8
268	B:B:K57	B:B:Q75	9.49	Yes	No	2	9	9
269	B:B:K57	B:B:W332	19.73	Yes	Yes	2	9	9
270	B:B:Q75	B:B:Y59	9.02	No	No	2	9	8
271	B:B:L70	B:B:M61	5.65	No	No	0	5	6
272	B:B:L336	B:B:M61	8.48	No	No	0	7	6
273	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
274	B:B:H62	B:B:R150	15.8	No	No	0	6	6
275	B:B:L70	B:B:W63	10.25	No	Yes	0	5	7
276	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
277	B:B:T321	B:B:W63	10.92	No	Yes	0	7	7
278	B:B:A328	B:B:W63	5.19	No	Yes	0	5	7
279	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
280	B:B:D322	B:B:T65	4.34	No	No	0	1	1
281	B:B:D66	B:B:L69	5.43	No	No	0	8	5
282	B:B:D323	B:B:S67	10.31	No	No	0	7	5
283	B:B:D83	B:B:R68	15.48	Yes	No	0	8	5
284	B:B:R68	B:B:Y85	24.69	No	No	0	5	4
285	B:B:D83	B:B:L69	5.43	Yes	No	0	8	5
286	B:B:L70	B:B:W82	6.83	No	Yes	0	5	9
287	B:B:V71	B:B:Y105	5.05	No	Yes	0	8	6
288	B:B:S72	B:B:W82	6.18	No	Yes	4	9	9
289	B:B:D76	B:B:S74	7.36	No	No	0	9	9
290	B:B:Q75	B:B:W99	6.57	No	Yes	2	9	9
291	B:B:D76	B:B:K78	8.3	No	No	0	9	8
292	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
293	B:B:I93	B:B:L79	5.71	Yes	No	0	7	7
294	B:B:I80	B:B:W82	12.92	No	Yes	4	8	9
295	B:B:I80	B:B:K89	5.82	No	Yes	4	8	9
296	B:B:H91	B:B:I81	6.63	No	No	0	5	7
297	B:B:I81	B:B:L126	4.28	No	No	0	7	5
298	B:B:K89	B:B:W82	11.6	Yes	Yes	4	9	9
299	B:B:D83	B:B:T86	5.78	Yes	Yes	4	8	6
300	B:B:S84	G:G:F61	5.28	No	Yes	0	5	8
301	B:B:Y85	G:G:P60	11.13	No	Yes	22	4	9
302	B:B:Y85	G:G:F61	6.19	No	Yes	22	4	8
303	B:B:N88	B:B:T86	5.85	No	Yes	4	7	6
304	B:B:H91	B:B:V90	13.84	No	No	0	5	5
305	B:B:H91	B:B:V133	6.92	No	No	0	5	4
306	B:B:I93	B:B:Y124	4.84	Yes	Yes	13	7	6
307	B:B:I93	B:B:V133	7.68	Yes	No	13	7	4
308	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
309	B:B:C114	B:B:L95	4.76	No	Yes	13	8	8
310	B:B:L95	B:B:Y124	5.86	Yes	Yes	13	8	6
311	B:B:E138	B:B:R96	4.65	No	No	0	6	6
312	B:B:D118	B:B:S97	10.31	No	No	0	9	8
313	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
314	B:B:L117	B:B:W99	6.83	No	Yes	0	9	9
315	B:B:L117	B:B:M101	4.24	No	Yes	0	9	9
316	B:B:M101	B:B:Y145	7.18	Yes	Yes	0	9	8
317	B:B:C149	B:B:T102	5.07	No	No	0	8	8
318	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
319	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
320	B:B:N110	B:B:S108	8.94	No	No	23	4	6
321	B:B:D154	B:B:S108	10.31	No	No	23	6	6
322	B:B:K127	B:B:N110	6.99	No	No	0	4	4
323	B:B:D154	B:B:N110	4.04	No	No	23	6	4
324	B:B:N125	B:B:Y111	9.3	No	Yes	0	4	4
325	B:B:S136	B:B:Y111	3.82	No	Yes	0	4	4
326	B:B:D154	B:B:Y111	8.05	No	Yes	0	6	4
327	B:B:L126	B:B:V112	5.96	No	No	0	5	8
328	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
329	B:B:C114	B:B:Y124	4.03	No	Yes	13	8	6
330	B:B:G144	B:B:N119	5.09	No	No	0	8	9
331	B:B:E138	B:B:I120	5.47	No	No	0	6	6
332	B:B:A140	B:B:I120	6.5	No	No	0	5	6
333	B:B:C121	B:B:C149	3.64	No	No	1	8	8
334	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
335	B:B:E138	B:B:S122	4.31	No	No	0	6	8
336	B:B:F151	B:B:I123	3.77	Yes	No	0	9	6
337	B:B:I123	B:B:I171	4.42	No	No	0	6	6
338	B:B:V133	B:B:Y124	3.79	No	Yes	13	4	6
339	B:B:V135	B:B:Y124	7.57	No	Yes	0	4	6
340	B:B:N125	B:B:T128	5.85	No	Yes	0	4	3
341	B:B:E130	B:B:T128	4.23	No	Yes	24	3	3
342	B:B:R134	B:B:T128	6.47	No	Yes	24	3	3
343	B:B:E130	B:B:R134	9.3	No	No	24	3	3
344	B:B:N132	B:B:R134	7.23	No	No	0	3	3
345	B:B:G174	B:B:R137	4.5	No	No	0	4	5
346	B:B:L139	B:B:W169	13.67	No	Yes	0	9	8
347	B:B:G141	B:B:W169	4.22	No	Yes	0	5	8
348	B:B:H142	B:B:L146	5.14	Yes	No	1	9	7
349	B:B:H142	B:B:T159	6.85	Yes	Yes	1	9	9
350	B:B:H142	B:B:S161	13.95	Yes	No	1	9	9
351	B:B:D163	B:B:H142	8.82	Yes	Yes	1	9	9
352	B:B:D163	B:B:T143	8.67	Yes	No	0	9	5
353	B:B:G162	B:B:Y145	8.69	No	Yes	1	9	8
354	B:B:D186	B:B:Y145	10.34	Yes	Yes	1	9	8
355	B:B:L146	B:B:T159	4.42	No	Yes	1	7	9
356	B:B:S147	B:B:S160	4.89	No	No	0	9	6
357	B:B:C148	B:B:R150	4.18	No	No	0	6	6
358	B:B:C148	B:B:L190	4.76	No	No	0	6	5
359	B:B:F151	B:B:I157	8.79	Yes	No	0	9	7
360	B:B:L152	B:B:Q156	6.65	Yes	No	0	3	5
361	B:B:L152	B:B:L192	4.15	Yes	No	0	3	5
362	B:B:L152	B:B:V213	4.47	Yes	No	0	3	4
363	B:B:D153	B:B:Q156	13.05	No	No	0	5	5
364	B:B:D170	B:B:N155	4.04	Yes	No	0	9	3
365	B:B:L168	B:B:Q156	3.99	No	No	0	6	5
366	B:B:I157	B:B:I171	4.42	No	No	0	7	6
367	B:B:L190	B:B:V158	4.47	No	No	0	5	5
368	B:B:F199	B:B:V158	5.24	Yes	No	0	9	5
369	B:B:T159	B:B:W169	9.7	Yes	Yes	1	9	8
370	B:B:S160	B:B:V187	8.08	No	No	0	6	9
371	B:B:G162	B:B:S161	3.71	No	No	1	9	9
372	B:B:D163	B:B:S161	10.31	Yes	No	1	9	9
373	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
374	B:B:D163	B:B:T165	13.01	Yes	No	0	9	7
375	B:B:C166	B:B:F180	4.19	No	Yes	10	8	7
376	B:B:C166	B:B:V187	5.12	No	No	0	8	9
377	B:B:C166	B:B:F199	4.19	No	Yes	10	8	9
378	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
379	B:B:A167	B:B:Q176	6.06	No	No	1	4	4
380	B:B:L168	B:B:T178	7.37	No	No	0	6	4
381	B:B:Q176	B:B:W169	13.14	No	Yes	1	4	8
382	B:B:D170	B:B:T173	8.67	Yes	No	0	9	5
383	B:B:Q176	B:B:T179	5.67	No	No	0	4	4
384	B:B:F180	B:B:T178	5.19	Yes	No	0	7	4
385	B:B:F180	B:B:F199	12.86	Yes	Yes	10	7	9
386	B:B:F180	B:B:W211	15.03	Yes	Yes	10	7	8
387	B:B:H183	B:B:V187	5.54	Yes	No	0	9	9
388	B:B:H183	B:B:S201	6.97	Yes	No	0	9	9
389	B:B:A203	B:B:H183	8.78	No	Yes	0	8	9
390	B:B:D205	B:B:H183	5.04	No	Yes	0	9	9
391	B:B:H183	B:B:K209	14.41	Yes	Yes	0	9	6
392	B:B:G185	B:B:T184	3.64	No	No	0	5	3
393	B:B:D205	B:B:T184	10.12	No	No	0	9	3
394	B:B:C204	B:B:G185	3.92	Yes	No	0	7	5
395	B:B:C204	B:B:D186	7.78	Yes	Yes	1	7	9
396	B:B:I232	B:B:S189	4.64	No	No	0	8	7
397	B:B:A193	B:B:F234	4.16	No	No	0	4	5
398	B:B:G238	B:B:P194	4.06	No	No	0	7	4
399	B:B:D195	B:B:R197	8.34	No	No	0	5	5
400	B:B:R197	B:B:R214	13.86	No	No	0	5	9
401	B:B:L198	B:B:L210	4.15	No	No	0	3	5
402	B:B:L198	B:B:R219	3.64	No	No	0	3	5
403	B:B:F199	B:B:W211	13.03	Yes	Yes	10	9	8
404	B:B:I232	B:B:V200	6.14	No	No	9	8	6
405	B:B:F234	B:B:V200	7.87	No	No	0	5	6
406	B:B:F241	B:B:V200	7.87	Yes	No	9	6	6
407	B:B:S201	B:B:W211	7.41	No	Yes	0	9	8
408	B:B:C204	B:B:D228	7.78	Yes	No	1	7	9
409	B:B:D205	B:B:S207	8.83	No	No	0	9	5
410	B:B:K209	B:B:S207	4.59	Yes	No	0	6	5
411	B:B:K209	B:B:W211	6.96	Yes	Yes	10	6	8
412	B:B:C218	B:B:K209	6.47	No	Yes	10	5	6
413	B:B:K209	B:B:T221	10.51	Yes	No	0	6	7
414	B:B:L210	B:B:Q220	6.65	No	Yes	0	5	7
415	B:B:L210	B:B:L255	4.15	No	No	0	5	6
416	B:B:C218	B:B:W211	7.84	No	Yes	10	5	8
417	B:B:D212	B:B:E215	7.8	No	No	0	9	3
418	B:B:D212	B:B:R219	17.87	No	No	0	9	5
419	B:B:E215	B:B:M217	9.47	No	No	0	3	3
420	B:B:M217	G:G:M21	4.33	No	No	0	3	1
421	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
422	B:B:F222	B:B:Q220	7.03	Yes	Yes	9	8	7
423	B:B:D258	B:B:Q220	6.53	Yes	Yes	9	7	7
424	B:B:Q220	G:G:I25	5.49	Yes	No	0	7	2
425	B:B:T221	G:G:E22	8.47	No	No	0	7	9
426	B:B:F222	B:B:F241	10.72	Yes	Yes	9	8	6
427	B:B:F222	B:B:F253	10.72	Yes	Yes	9	8	6
428	B:B:D258	B:B:F222	7.17	Yes	Yes	9	7	8
429	B:B:H225	B:B:I229	9.28	Yes	No	0	9	7
430	B:B:H225	B:B:T243	8.21	Yes	No	0	9	8
431	B:B:H225	B:B:S245	12.55	Yes	No	25	9	9
432	B:B:D247	B:B:H225	7.56	Yes	Yes	25	9	9
433	B:B:H225	B:B:R251	20.31	Yes	Yes	0	9	8
434	B:B:D247	B:B:E226	6.5	Yes	No	0	9	3
435	B:B:D246	B:B:N230	13.46	Yes	No	1	9	9
436	B:B:F241	B:B:I232	5.02	Yes	No	9	6	8
437	B:B:F235	B:B:P236	10.11	Yes	No	0	6	7
438	B:B:F235	B:B:N237	9.67	Yes	Yes	0	6	5
439	B:B:F235	B:B:F278	10.72	Yes	No	0	6	7
440	B:B:G282	B:B:P236	4.06	No	No	0	9	7
441	B:B:P236	G:G:Y40	5.56	No	No	0	7	6
442	B:B:N237	B:B:N239	12.26	Yes	No	0	5	2
443	B:B:N237	G:G:Y40	6.98	Yes	No	0	5	6
444	B:B:N239	B:B:R256	20.49	No	No	0	2	9
445	B:B:F241	B:B:F253	9.65	Yes	Yes	9	6	6
446	B:B:F253	B:B:T243	7.78	Yes	No	0	6	8
447	B:B:G244	B:B:I273	5.29	No	No	0	5	6
448	B:B:D247	B:B:S245	5.89	Yes	No	25	9	9
449	B:B:D247	B:B:T249	11.56	Yes	No	0	9	6
450	B:B:R251	B:B:T249	6.47	Yes	No	0	8	6
451	B:B:S265	B:B:T249	4.8	No	No	0	2	6
452	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
453	B:B:C250	B:B:I273	6.55	No	No	0	8	6
454	B:B:F253	B:B:R251	4.28	Yes	Yes	0	6	8
455	B:B:R251	B:B:T263	7.76	Yes	No	0	8	1
456	B:B:L252	B:B:L261	6.92	No	No	0	7	5
457	B:B:L252	B:B:Y264	7.03	No	Yes	0	7	5
458	B:B:A257	B:B:D254	4.63	No	No	0	7	9
459	B:B:D254	B:B:L261	16.29	No	No	0	9	5
460	B:B:R256	G:G:D36	5.96	No	No	0	9	5
461	B:B:D258	G:G:E22	5.2	Yes	No	0	7	9
462	B:B:D258	G:G:R27	8.34	Yes	No	0	7	8
463	B:B:Q259	G:G:V30	8.6	No	No	0	6	8
464	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
465	B:B:W297	B:B:Y264	8.68	No	Yes	0	8	5
466	B:B:A302	B:B:Y264	4	No	Yes	0	2	5
467	B:B:H266	B:B:N268	14.03	No	No	0	4	4
468	B:B:H266	B:B:R304	6.77	No	No	0	4	5
469	B:B:I269	B:B:Y289	8.46	No	Yes	0	4	7
470	B:B:I269	B:B:R304	3.76	No	No	0	4	5
471	B:B:C271	B:B:Y289	4.03	No	Yes	26	5	7
472	B:B:C271	B:B:D291	6.22	No	No	26	5	8
473	B:B:I273	B:B:Y289	8.46	No	Yes	0	6	7
474	B:B:S275	B:B:T274	4.8	No	No	0	8	8
475	B:B:D290	B:B:T274	4.34	Yes	No	2	6	8
476	B:B:R314	B:B:T274	5.17	Yes	No	2	8	8
477	B:B:L318	B:B:S275	6.01	No	No	0	6	8
478	B:B:S277	B:B:V320	4.85	No	No	0	5	7
479	B:B:F278	B:B:L285	10.96	No	No	0	7	6
480	B:B:L284	B:B:S279	6.01	No	No	0	5	9
481	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
482	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
483	B:B:D298	B:B:R283	14.29	Yes	Yes	6	9	9
484	B:B:L300	B:B:R283	9.72	No	Yes	0	6	9
485	B:B:R283	G:G:L51	7.29	Yes	Yes	0	9	6
486	B:B:L284	B:B:V296	5.96	No	No	0	5	5
487	B:B:L284	G:G:L51	4.15	No	Yes	0	5	6
488	B:B:L286	B:B:V327	4.47	No	No	0	7	6
489	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
490	B:B:D291	B:B:Y289	5.75	No	Yes	26	8	7
491	B:B:N295	B:B:Y289	17.44	No	Yes	0	6	7
492	B:B:W297	B:B:Y289	6.75	No	Yes	0	8	7
493	B:B:D290	B:B:R314	10.72	Yes	Yes	2	6	8
494	B:B:D291	B:B:N293	5.39	No	No	0	8	5
495	B:B:F292	B:B:N313	4.83	No	No	0	4	7
496	B:B:N293	B:B:V307	4.43	No	No	0	5	3
497	B:B:A309	B:B:N293	6.25	No	No	0	3	5
498	B:B:C294	B:B:V315	5.12	No	No	0	5	7
499	B:B:N295	B:B:R304	14.46	No	No	0	6	5
500	B:B:D298	B:B:K301	8.3	Yes	No	6	9	5
501	B:B:D298	B:B:D303	5.32	Yes	No	6	9	2
502	B:B:L300	G:G:C41	4.76	No	No	0	6	7
503	B:B:D303	B:B:K301	8.3	No	No	6	2	5
504	B:B:L308	B:B:W339	21.64	No	Yes	0	7	9
505	B:B:H311	B:B:T329	6.85	Yes	No	0	9	8
506	B:B:H311	B:B:S331	15.34	Yes	No	11	9	9
507	B:B:D333	B:B:H311	7.56	Yes	Yes	11	9	9
508	B:B:H311	B:B:K337	10.48	Yes	Yes	11	9	6
509	B:B:D312	B:B:D333	9.31	No	Yes	0	5	9
510	B:B:D312	R:R:K647	11.06	No	No	0	5	9
511	B:B:D312	R:R:R650	10.72	No	No	0	5	8
512	B:B:N313	B:B:W332	10.17	No	Yes	0	7	9
513	B:B:R314	B:B:W332	26.99	Yes	Yes	2	8	9
514	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
515	B:B:D323	B:B:T321	7.23	No	No	0	7	7
516	B:B:G324	B:B:T321	3.64	No	No	0	9	7
517	B:B:D323	B:B:M325	8.32	No	No	0	7	5
518	B:B:M325	G:G:P49	8.39	No	No	0	5	7
519	B:B:M325	G:G:P60	8.39	No	Yes	0	5	9
520	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
521	B:B:V327	B:B:W339	3.68	No	Yes	0	6	9
522	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
523	B:B:D333	B:B:S331	8.83	Yes	No	11	9	9
524	B:B:D333	B:B:F335	9.55	Yes	No	0	9	4
525	B:B:F335	R:R:R650	9.62	No	No	0	4	8
526	B:B:K337	B:B:W339	8.12	Yes	Yes	11	6	9
527	B:B:I338	G:G:F61	3.77	No	Yes	0	5	8
528	B:B:N340	G:G:N59	10.9	No	No	0	9	9
529	G:G:I9	G:G:R13	6.26	No	No	0	2	6
530	G:G:A10	G:G:R13	4.15	No	No	0	2	6
531	G:G:L15	G:G:L19	4.15	No	No	0	2	9
532	G:G:K20	G:G:V16	6.07	No	Yes	0	6	7
533	G:G:E17	G:G:K20	5.4	No	No	0	6	6
534	G:G:M21	G:G:Q18	4.08	No	No	0	1	9
535	G:G:I28	G:G:K32	5.82	No	No	0	4	5
536	G:G:D36	G:G:K32	5.53	No	No	0	5	5
537	G:G:H44	G:G:Y40	21.78	No	No	0	6	6
538	G:G:E47	G:G:H44	7.39	No	No	0	3	6
539	G:G:D48	G:G:L51	9.5	Yes	Yes	0	9	6
540	G:G:E58	G:G:V54	4.28	No	No	0	5	6
541	G:G:E58	G:G:P55	14.15	No	No	0	5	5
542	G:G:E58	G:G:S57	8.62	No	No	0	5	6
543	G:G:N59	G:G:P60	6.52	No	Yes	0	9	9
544	G:G:F61	G:G:P60	4.33	Yes	Yes	22	8	9
545	L:L:?1	R:R:L620	5.51	Yes	No	0	0	9
546	L:L:?1	R:R:T624	5.87	Yes	No	0	0	9
547	L:L:?1	R:R:N763	12.29	Yes	No	0	0	5
548	L:L:?1	R:R:T765	10.26	Yes	No	0	0	5
549	L:L:?1	R:R:M853	5.63	Yes	No	0	0	8
550	L:L:?1	R:R:F856	8.48	Yes	Yes	0	0	9
551	R:R:A619	R:R:Q616	4.55	No	No	0	8	7
552	R:R:F622	R:R:I626	5.02	No	No	0	6	9
553	R:R:T624	R:R:T861	4.71	No	Yes	0	9	8
554	R:R:S675	R:R:Y625	8.9	No	No	0	7	8
555	R:R:G627	R:R:T861	3.64	No	Yes	0	9	8
556	R:R:C628	R:R:L672	4.76	No	No	0	9	9
557	R:R:N668	R:R:S631	4.47	No	No	0	9	9
558	R:R:G864	R:R:S631	3.71	No	No	0	9	9
559	R:R:L669	R:R:S632	4.5	No	No	0	8	9
560	R:R:F634	R:R:F865	10.72	No	Yes	0	9	7
561	R:R:F634	R:R:F868	18.22	No	Yes	0	9	9
562	R:R:L635	R:R:L665	4.15	No	No	0	9	8
563	R:R:G864	R:R:L635	5.13	No	No	0	9	9
564	R:R:F868	R:R:T638	6.49	Yes	No	28	9	9
565	R:R:C872	R:R:T638	8.45	No	No	28	9	9
566	R:R:C872	R:R:T641	5.07	No	No	0	9	9
567	R:R:T641	R:R:W882	13.34	No	No	0	9	9
568	R:R:I648	R:R:Y642	9.67	No	Yes	0	8	9
569	R:R:S654	R:R:Y642	3.82	No	Yes	0	9	9
570	R:R:L657	R:R:Y642	4.69	No	Yes	0	9	9
571	R:R:I658	R:R:Y642	7.25	No	Yes	0	9	9
572	R:R:A644	R:R:F645	4.16	No	No	0	7	9
573	R:R:F645	R:R:Q881	8.2	No	No	0	9	9
574	R:R:E646	R:R:R649	10.47	No	No	0	6	9
575	R:R:E646	R:R:R650	15.12	No	No	0	6	8
576	R:R:K647	R:R:Q881	8.14	No	No	0	9	9
577	R:R:I648	R:R:Q881	4.12	No	No	0	8	9
578	R:R:D651	R:R:P653	8.05	No	Yes	3	9	9
579	R:R:D651	R:R:S654	8.83	No	No	0	9	9
580	R:R:H710	R:R:Y652	4.36	Yes	No	3	9	8
581	R:R:Y652	R:R:Y726	20.85	No	Yes	3	8	8
582	R:R:I727	R:R:Y652	7.25	No	No	0	8	8
583	R:R:H710	R:R:P653	9.15	Yes	Yes	3	9	9
584	R:R:I727	R:R:K655	13.09	No	No	0	8	9
585	R:R:E707	R:R:I656	6.83	Yes	No	3	9	9
586	R:R:H710	R:R:I656	5.3	Yes	No	3	9	9
587	R:R:F730	R:R:I656	3.77	Yes	No	0	8	9
588	R:R:L657	R:R:Y871	5.86	No	No	0	9	8
589	R:R:Q659	R:R:W703	15.33	No	Yes	12	7	9
590	R:R:C731	R:R:Q659	6.1	No	No	12	8	7
591	R:R:Q659	R:R:W735	4.38	No	Yes	12	7	9
592	R:R:L660	R:R:L664	4.15	No	No	0	9	9
593	R:R:L664	R:R:S700	7.51	No	No	0	9	7
594	R:R:L664	R:R:Q863	5.32	No	Yes	0	9	9
595	R:R:F696	R:R:L666	14.61	Yes	No	0	9	5
596	R:R:L667	R:R:N668	4.12	No	No	0	9	9
597	R:R:L667	R:R:L697	4.15	No	No	0	9	9
598	R:R:F696	R:R:I670	8.79	Yes	No	0	9	6
599	R:R:F671	R:R:F769	4.29	No	Yes	0	9	9
600	R:R:D674	R:R:V689	5.84	No	No	0	9	8
601	R:R:D674	R:R:F769	14.33	No	Yes	0	9	9
602	R:R:C770	R:R:D674	6.22	No	No	0	9	9
603	R:R:I677	R:R:W676	7.05	No	No	0	8	9
604	R:R:I677	R:R:L679	5.71	No	Yes	0	8	8
605	R:R:L679	R:R:T682	4.42	Yes	No	0	8	4
606	R:R:N681	R:R:Y680	4.65	No	No	0	3	8
607	R:R:F685	R:R:T682	11.67	No	No	0	8	4
608	R:R:I687	R:R:R683	6.26	No	No	0	9	5
609	R:R:D751	R:R:R683	9.53	No	No	0	4	5
610	R:R:C686	R:R:I755	4.91	No	No	0	9	6
611	R:R:C686	R:R:C770	7.28	No	No	29	9	9
612	R:R:A690	R:R:Y753	4	No	Yes	0	9	9
613	R:R:L746	R:R:V691	7.45	No	No	15	8	6
614	R:R:V691	R:R:Y753	11.36	No	Yes	15	6	9
615	R:R:L693	R:R:W771	5.69	No	No	0	9	9
616	R:R:H694	R:R:L698	9	Yes	No	0	9	9
617	R:R:H694	R:R:V742	4.15	Yes	No	0	9	9
618	R:R:H694	R:R:Y753	13.07	Yes	Yes	15	9	9
619	R:R:H694	R:R:I772	7.95	Yes	No	15	9	8
620	R:R:H694	R:R:T781	5.48	Yes	No	0	9	7
621	R:R:H694	R:R:V782	5.54	Yes	No	0	9	9
622	R:R:F696	R:R:Y695	5.16	Yes	Yes	0	9	9
623	R:R:V699	R:R:Y695	8.83	No	Yes	12	7	9
624	R:R:W735	R:R:Y695	6.75	Yes	Yes	12	9	9
625	R:R:A739	R:R:Y695	4	No	Yes	0	9	9
626	R:R:V742	R:R:Y695	5.05	No	Yes	0	9	9
627	R:R:F701	R:R:L697	8.53	No	No	0	9	9
628	R:R:L698	R:R:P738	4.93	No	Yes	0	9	9
629	R:R:V699	R:R:W735	12.26	No	Yes	12	7	9
630	R:R:P738	R:R:V699	5.3	Yes	No	0	9	7
631	R:R:F701	R:R:F786	10.72	No	No	0	9	9
632	R:R:F701	R:R:W838	10.02	No	Yes	0	9	9
633	R:R:G734	R:R:T702	5.46	No	No	0	9	9
634	R:R:P738	R:R:T702	5.25	Yes	No	0	9	9
635	R:R:T702	R:R:Y785	4.99	No	No	0	9	9
636	R:R:L706	R:R:W703	6.83	No	Yes	0	9	9
637	R:R:C731	R:R:W703	3.92	No	Yes	12	8	9
638	R:R:W703	R:R:W735	13.12	Yes	Yes	12	9	9
639	R:R:M704	R:R:W838	5.82	No	Yes	14	9	9
640	R:R:M704	R:R:Q863	5.44	No	Yes	14	9	9
641	R:R:F730	R:R:L706	8.53	Yes	No	0	8	9
642	R:R:E707	R:R:H710	3.69	Yes	Yes	3	9	9
643	R:R:E707	R:R:L833	5.3	Yes	No	0	9	9
644	R:R:F709	R:R:L713	7.31	No	No	0	7	5
645	R:R:F709	R:R:F730	4.29	No	Yes	0	7	8
646	R:R:H710	R:R:Y726	7.62	Yes	Yes	3	9	8
647	R:R:V716	R:R:Y712	8.83	No	No	0	9	9
648	R:R:L715	R:R:Q803	3.99	No	No	0	8	9
649	R:R:I723	R:R:Y726	7.25	No	Yes	0	6	8
650	R:R:K725	R:R:R724	12.38	No	No	0	5	7
651	R:R:K725	R:R:L728	7.05	No	No	0	5	7
652	R:R:F730	R:R:Y726	14.44	Yes	Yes	0	8	8
653	R:R:G734	R:R:V733	3.68	No	No	0	9	4
654	R:R:V745	R:R:Y753	6.31	No	Yes	0	8	9
655	R:R:V745	R:R:V777	4.81	No	No	0	8	7
656	R:R:L746	R:R:Y753	4.69	No	Yes	15	8	9
657	R:R:N752	R:R:S749	5.96	No	No	0	8	6
658	R:R:N752	R:R:S774	4.47	No	No	0	8	7
659	R:R:I772	R:R:Y753	4.84	No	Yes	15	8	9
660	R:R:F769	R:R:G764	4.52	Yes	No	0	9	5
661	R:R:P766	R:R:T765	5.25	No	No	0	5	5
662	R:R:F769	R:R:P766	7.22	Yes	No	0	9	5
663	R:R:D767	R:R:D768	10.65	No	No	0	8	4
664	R:R:S774	R:R:V777	6.46	No	No	0	7	7
665	R:R:F778	R:R:Y779	7.22	Yes	No	31	9	9
666	R:R:F778	R:R:V782	7.87	Yes	No	0	9	9
667	R:R:F778	R:R:V783	3.93	Yes	No	0	9	9
668	R:R:F778	R:R:W845	5.01	Yes	No	31	9	8
669	R:R:W845	R:R:Y779	3.86	No	No	31	8	9
670	R:R:G784	R:R:V783	3.68	No	No	0	8	9
671	R:R:F786	R:R:F790	7.5	No	Yes	30	9	9
672	R:R:F786	R:R:F842	6.43	No	No	30	9	9
673	R:R:I789	R:R:N793	4.25	No	Yes	0	7	9
674	R:R:F790	R:R:V794	7.87	Yes	No	0	9	2
675	R:R:F790	R:R:G839	6.02	Yes	No	0	9	9
676	R:R:F790	R:R:F842	8.57	Yes	No	30	9	9
677	R:R:L834	R:R:N793	4.12	No	Yes	0	9	9
678	R:R:M796	R:R:V799	7.61	No	No	0	9	9
679	R:R:F797	R:R:L801	8.53	Yes	No	0	9	7
680	R:R:F797	R:R:L830	6.09	Yes	No	0	9	8
681	R:R:F797	R:R:T831	7.78	Yes	No	0	9	8
682	R:R:F797	R:R:L834	3.65	Yes	No	0	9	9
683	R:R:F797	R:R:I836	6.28	Yes	No	0	9	9
684	R:R:Q803	R:R:V799	4.3	No	No	0	9	9
685	R:R:R806	R:R:V802	5.23	No	No	0	9	7
686	R:R:K808	R:R:R817	9.9	No	Yes	0	9	7
687	R:R:Q816	R:R:R817	15.19	No	Yes	0	6	7
688	R:R:D823	R:R:T819	7.23	No	No	0	7	6
689	R:R:Q822	R:R:R825	5.84	No	No	0	7	9
690	R:R:D823	R:R:L824	5.43	No	No	0	7	5
691	R:R:A874	R:R:R825	5.53	No	No	0	5	9
692	R:R:A828	R:R:F870	5.55	No	No	0	5	9
693	R:R:F870	R:R:G829	6.02	No	No	0	9	9
694	R:R:G829	R:R:Y871	4.35	No	No	0	9	8
695	R:R:F832	R:R:T837	7.78	No	No	0	6	9
696	R:R:F832	R:R:F866	21.43	No	No	0	6	9
697	R:R:L833	R:R:Y871	12.89	No	No	0	9	8
698	R:R:N860	R:R:T837	5.85	No	No	0	9	9
699	R:R:F856	R:R:W838	4.01	Yes	Yes	14	9	9
700	R:R:N860	R:R:W838	24.86	No	Yes	14	9	9
701	R:R:Q863	R:R:W838	6.57	Yes	Yes	14	9	9
702	R:R:A841	R:R:F856	4.16	No	Yes	0	9	9
703	R:R:F843	R:R:F852	9.65	No	Yes	0	9	9
704	R:R:F852	R:R:N849	6.04	Yes	No	0	9	8
705	R:R:F856	R:R:N860	7.25	Yes	No	14	9	9
706	R:R:F865	R:R:L862	3.65	Yes	No	27	7	7
707	R:R:F866	R:R:L862	4.87	No	No	27	9	7
708	R:R:F865	R:R:F866	5.36	Yes	No	27	7	9
709	R:R:F865	R:R:I869	7.54	Yes	No	0	7	6
710	R:R:C872	R:R:F868	6.98	No	Yes	28	9	9
711	R:R:F870	R:R:I869	3.77	No	No	0	9	6
712	R:R:K875	R:R:N877	8.39	No	No	0	9	8
713	R:R:K875	R:R:V878	4.55	No	No	0	9	9
714	R:R:E876	R:R:R879	6.98	No	No	0	8	9
715	R:R:V878	R:R:W882	4.9	No	No	0	9	9
716	B:B:I81	B:B:Y105	3.63	No	Yes	0	7	6
717	B:B:I123	B:B:Y111	3.63	No	Yes	0	6	4
718	A:A:F312	A:A:N264	3.62	Yes	No	0	8	9
719	B:B:A73	B:B:C103	3.61	No	No	0	9	8
720	R:R:M796	R:R:Y712	3.59	No	No	0	9	9
721	A:A:R228	B:B:D186	3.57	Yes	Yes	0	9	9
722	A:A:D354	R:R:R817	3.57	No	Yes	0	3	7
723	R:R:P750	R:R:S749	3.56	No	No	0	6	6
724	B:B:G202	B:B:I229	3.53	No	No	0	6	7
725	R:R:G705	R:R:I789	3.53	No	No	0	8	7
726	A:A:L393	A:A:Y391	3.52	Yes	Yes	3	8	4
727	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
728	R:R:L620	R:R:Y854	3.52	No	No	0	9	9
729	A:A:P326	A:A:T335	3.5	No	No	0	1	4
730	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
731	B:B:E215	B:B:R214	3.49	No	No	0	3	9
732	B:B:G310	B:B:K337	3.49	No	Yes	0	5	6
733	R:R:D768	R:R:Y680	3.45	No	No	0	4	8
734	B:B:C233	B:B:S277	3.44	No	No	0	3	5
735	B:B:C317	B:B:S316	3.44	No	No	0	7	9
736	A:A:A226	A:A:S205	3.42	No	No	0	9	7
737	A:A:C365	A:A:V367	3.42	No	No	0	8	9
738	B:B:G319	B:B:L318	3.42	No	No	0	5	6
739	B:B:G330	B:B:L336	3.42	No	No	0	5	7
740	B:B:A73	B:B:V100	3.39	No	No	0	9	9
741	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
742	B:B:G238	B:B:N237	3.39	No	Yes	0	7	5
743	R:R:I737	R:R:P738	3.39	No	Yes	0	4	9
744	B:B:C148	B:B:T102	3.38	No	No	0	6	8
745	B:B:C121	B:B:T159	3.38	No	Yes	1	8	9
746	B:B:C149	B:B:T159	3.38	No	Yes	1	8	9
747	R:R:C628	R:R:T861	3.38	No	Yes	0	9	8
748	R:R:C661	R:R:T638	3.38	No	No	0	9	9
749	B:B:E260	B:B:G224	3.27	No	No	0	6	6
750	A:A:I26	B:B:A92	3.25	No	No	0	9	6
751	A:A:A243	A:A:I288	3.25	No	No	0	8	9
752	B:B:I18	G:G:A23	3.25	No	No	0	7	8
753	A:A:D323	A:A:P321	3.22	No	No	0	4	5
754	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
755	R:R:F692	R:R:F696	3.22	No	Yes	0	7	9
756	R:R:F832	R:R:F859	3.22	No	No	0	6	8
757	R:R:F840	R:R:F852	3.22	No	Yes	0	9	9
758	R:R:F840	R:R:F856	3.22	No	Yes	0	9	9
759	R:R:A844	R:R:M853	3.22	No	No	0	9	8
760	A:A:A366	A:A:K53	3.21	No	No	0	9	9
761	A:A:A249	A:A:K293	3.21	No	Yes	0	8	9
762	A:A:V301	A:A:V334	3.21	No	Yes	0	7	4
763	B:B:V320	B:B:V327	3.21	No	No	0	7	6
764	B:B:C294	B:B:L308	3.17	No	No	0	5	7
765	R:R:C661	R:R:L639	3.17	No	No	0	9	9
766	R:R:T781	R:R:V741	3.17	No	No	0	7	7
767	B:B:L7	G:G:A12	3.15	No	No	0	8	5
768	B:B:A240	G:G:L37	3.15	No	No	0	6	7
769	B:B:A242	B:B:L285	3.15	No	No	0	4	6
770	R:R:A662	R:R:L639	3.15	No	No	0	4	9
771	A:A:E327	A:A:P328	3.14	No	No	0	4	1
772	B:B:T165	B:B:T181	3.14	No	No	0	7	2
773	B:B:T177	B:B:T178	3.14	No	No	0	4	4
774	R:R:A708	R:R:N793	3.13	No	Yes	0	9	9
775	A:A:I341	A:A:S250	3.1	No	No	0	8	6
776	B:B:A28	B:B:D27	3.09	No	No	0	4	8
777	B:B:D254	G:G:A33	3.09	No	No	0	9	7
778	A:A:I245	A:A:V375	3.07	No	No	0	7	9
779	B:B:M262	B:B:S31	3.07	No	No	0	4	1
780	R:R:I798	R:R:V794	3.07	No	No	0	6	2
781	B:B:C25	B:B:Q259	3.05	No	No	0	3	6
782	A:A:I56	A:A:T55	3.04	No	No	0	7	9
783	A:A:I244	A:A:T285	3.04	No	No	0	8	7
784	R:R:I780	R:R:T781	3.04	No	No	0	9	7
785	A:A:A22	A:A:E21	3.02	No	No	0	4	2
786	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
787	B:B:F253	B:B:G224	3.01	Yes	No	0	6	6
788	R:R:F769	R:R:W771	3.01	Yes	No	0	9	9
789	A:A:L393	R:R:S826	3	Yes	No	0	8	9
790	A:A:L297	A:A:V301	2.98	Yes	No	0	8	7
791	A:A:L302	A:A:V334	2.98	No	Yes	0	2	4
792	R:R:L830	R:R:V800	2.98	No	No	0	8	9
793	A:A:L282	A:A:T285	2.95	No	No	0	9	7
794	A:A:T350	R:R:L813	2.95	No	No	0	4	8
795	B:B:L51	B:B:T87	2.95	No	No	0	9	5
796	A:A:I235	A:A:I276	2.94	No	No	0	9	8
797	A:A:I244	A:A:I276	2.94	No	No	0	8	8
798	B:B:D246	B:B:S227	2.94	Yes	No	0	9	6
799	B:B:D247	B:B:S227	2.94	Yes	No	0	9	6
800	R:R:I623	R:R:I858	2.94	No	No	0	9	9
801	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
802	A:A:I245	A:A:L43	2.85	No	No	0	7	7
803	A:A:I245	A:A:L45	2.85	No	No	0	7	8
804	A:A:I308	A:A:L297	2.85	No	Yes	0	7	8
805	B:B:E10	G:G:V16	2.85	No	Yes	0	8	7
806	R:R:I626	R:R:L630	2.85	No	No	0	9	5
807	A:A:E330	A:A:T335	2.82	Yes	No	0	3	4
808	R:R:K717	R:R:L713	2.82	No	No	0	9	5
809	B:B:G53	B:B:W82	2.81	No	Yes	0	9	9
810	R:R:G835	R:R:W838	2.81	No	Yes	0	9	9
811	A:A:K17	A:A:N14	2.8	No	No	0	4	3
812	B:B:M45	B:B:N340	2.8	No	No	0	4	9
813	B:B:D118	B:B:I120	2.8	No	No	0	9	6
814	B:B:C25	G:G:R27	2.79	No	No	0	3	8
815	R:R:C787	R:R:F842	2.79	No	No	0	6	9
816	A:A:A337	A:A:F315	2.77	No	No	0	8	6
817	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
818	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
819	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
820	R:R:L665	R:R:L669	2.77	No	No	0	8	8
821	R:R:I867	R:R:Q863	2.74	No	Yes	0	9	9
822	B:B:I37	G:G:E42	2.73	Yes	No	0	2	1
823	R:R:M618	R:R:Q616	2.72	No	No	0	5	7
824	A:A:K216	A:A:Q213	2.71	No	No	0	4	3
825	A:A:K271	A:A:Q267	2.71	No	No	0	5	4
826	R:R:K810	R:R:Q816	2.71	No	No	0	7	6
827	R:R:K811	R:R:Q816	2.71	No	No	0	9	6
828	A:A:E21	A:A:K25	2.7	No	No	0	2	5
829	A:A:Y37	B:B:A56	2.67	No	No	0	4	7
830	B:B:A299	B:B:Y264	2.67	No	Yes	0	5	5
831	R:R:A619	R:R:Y854	2.67	No	No	0	8	9
832	B:B:F234	B:B:S191	2.64	No	No	0	5	8
833	R:R:F868	R:R:V637	2.62	Yes	No	0	9	4
834	B:B:D170	B:B:E172	2.6	Yes	No	0	9	6
835	R:R:A663	R:R:W735	2.59	No	Yes	0	9	9
836	A:A:E10	A:A:Q12	2.55	No	No	0	2	2
837	R:R:V850	R:R:Y854	2.52	No	No	0	5	9
838	A:A:F212	A:A:I372	2.51	No	No	0	9	8
839	R:R:F859	R:R:I858	2.51	No	No	0	8	9
840	R:R:F634	R:R:L630	2.44	No	No	0	9	5
841	R:R:F859	R:R:L855	2.44	No	No	0	8	9
842	B:B:L139	B:B:R137	2.43	No	No	0	9	5
843	R:R:F719	R:R:N720	2.42	Yes	No	0	9	9
844	A:A:D223	A:A:F208	2.39	No	No	0	9	5
845	A:A:D229	A:A:R228	2.38	No	Yes	0	8	9
846	A:A:D284	A:A:R356	2.38	No	No	0	4	2
847	R:R:N775	R:R:Y779	2.33	No	No	0	6	9
848	B:B:G115	B:B:G116	2.11	No	No	0	9	9
849	R:R:G736	R:R:P738	2.03	No	Yes	0	9	9
850	R:R:R879	R:R:W882	2	No	No	0	9	9
851	B:B:C294	B:B:G288	1.96	No	No	0	5	7
852	A:A:A48	A:A:G49	1.95	No	No	0	8	8
853	A:A:A249	A:A:G52	1.95	No	No	0	8	9
854	A:A:A226	A:A:G206	1.95	No	No	0	9	8
855	B:B:A208	B:B:G202	1.95	No	No	0	6	6
856	R:R:A815	R:R:G814	1.95	No	No	0	4	8
857	A:A:A324	A:A:P326	1.87	No	No	0	3	1
858	A:A:G52	A:A:S51	1.86	No	No	0	9	9
859	R:R:G629	R:R:S632	1.86	No	No	0	9	9
860	A:A:G225	A:A:V224	1.84	No	No	0	9	9
861	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
862	B:B:G244	B:B:V276	1.84	No	No	0	5	6
863	B:B:G306	B:B:V296	1.84	No	No	0	4	5
864	B:B:G306	B:B:V307	1.84	No	No	0	4	3
865	B:B:G131	B:B:T128	1.82	No	Yes	0	4	3
866	B:B:G182	B:B:T181	1.82	No	No	0	6	2
867	B:B:A60	B:B:C103	1.81	No	No	0	7	8
868	A:A:A269	A:A:A48	1.79	No	No	0	9	8
869	G:G:P49	G:G:V54	1.77	No	No	0	7	6
870	R:R:G754	R:R:I687	1.76	No	No	0	9	9
871	A:A:P326	A:A:T325	1.75	No	No	0	1	2
872	B:B:P107	B:B:T65	1.75	No	No	0	6	1
873	G:G:P53	G:G:T52	1.75	No	No	0	8	4
874	B:B:A11	G:G:V16	1.7	No	Yes	0	5	7
875	B:B:A231	B:B:V276	1.7	No	No	0	5	6
876	R:R:G754	R:R:N773	1.7	No	No	0	9	5
877	B:B:D246	B:B:G272	1.68	Yes	No	0	9	4
878	B:B:D290	B:B:G272	1.68	Yes	No	0	6	4
879	R:R:A857	R:R:T861	1.68	No	Yes	0	7	8
880	A:A:E330	A:A:G329	1.64	Yes	No	0	3	7
881	B:B:A248	B:B:I269	1.62	No	No	0	5	4
882	R:R:S636	R:R:V637	1.62	No	No	0	9	4
883	R:R:S743	R:R:V742	1.62	No	No	0	7	9
884	R:R:S774	R:R:V776	1.62	No	No	0	7	5
885	B:B:D38	B:B:P39	1.61	No	No	0	1	1
886	R:R:D751	R:R:P750	1.61	No	No	0	4	6
887	B:B:S207	B:B:T223	1.6	No	No	0	5	2
888	R:R:T641	R:R:V640	1.59	No	No	0	9	8
889	R:R:C686	R:R:L679	1.59	No	Yes	29	9	8
890	R:R:C770	R:R:L679	1.59	No	Yes	29	9	8
891	B:B:L4	G:G:A12	1.58	No	No	0	4	5
892	B:B:L14	G:G:A23	1.58	Yes	No	0	8	8
893	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
894	R:R:T621	R:R:T765	1.57	No	No	0	9	5
895	A:A:A39	R:R:N720	1.56	No	No	0	5	9
896	B:B:I33	G:G:S31	1.55	No	No	0	3	9
897	G:G:I9	G:G:S8	1.55	No	No	0	2	4
898	R:R:I633	R:R:S632	1.55	No	No	0	9	9
899	R:R:I748	R:R:S749	1.55	No	No	0	5	6
900	R:R:I744	R:R:V740	1.54	No	No	0	8	5
901	R:R:I798	R:R:V802	1.54	No	No	0	6	7
902	A:A:G49	A:A:R265	1.5	No	No	0	8	9
903	A:A:L297	A:A:S251	1.5	Yes	Yes	0	8	9
904	B:B:G41	B:B:R42	1.5	No	No	0	1	2
905	R:R:L672	R:R:S675	1.5	No	No	0	9	7
906	R:R:G684	R:R:R683	1.5	No	No	0	6	5
907	R:R:K717	R:R:T721	1.5	No	No	0	9	7
908	B:B:L7	G:G:V16	1.49	No	Yes	0	8	7
909	R:R:N849	R:R:V848	1.48	No	No	0	8	7
910	B:B:L152	B:B:T196	1.47	Yes	No	0	3	1
911	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
912	R:R:I744	R:R:I748	1.47	No	No	0	8	5
913	R:R:D823	R:R:S826	1.47	No	No	0	7	9
914	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
915	G:G:A43	G:G:H44	1.46	No	No	0	4	6
916	B:B:D170	B:B:T177	1.45	Yes	No	0	9	4
917	R:R:I723	R:R:K729	1.45	No	No	0	6	9
918	R:R:M617	R:R:M618	1.44	No	No	0	4	5
919	R:R:Q822	R:R:S820	1.44	No	No	0	7	6
920	A:A:Q35	A:A:V36	1.43	No	No	0	3	2
921	A:A:L393	R:R:I827	1.43	Yes	No	3	8	7
922	R:R:I677	R:R:L673	1.43	No	No	0	8	8
923	R:R:I732	R:R:L728	1.43	No	No	0	5	7
924	R:R:I827	R:R:L801	1.43	No	No	0	7	7
925	R:R:I827	R:R:L804	1.43	No	No	3	7	9
926	B:B:Q175	B:B:T173	1.42	No	No	0	4	5
927	A:A:E370	A:A:T369	1.41	No	No	0	4	9
928	R:R:G846	R:R:W845	1.41	No	No	0	8	8
929	B:B:K301	B:B:N35	1.4	No	No	0	5	1
930	G:G:M21	G:G:N24	1.4	No	No	0	1	1
931	R:R:D768	R:R:I755	1.4	No	No	0	4	6
932	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
933	R:R:A873	R:R:F868	1.39	No	Yes	0	8	9
934	A:A:D310	A:A:K307	1.38	No	No	0	3	6
935	G:G:A56	G:G:R62	1.38	No	No	0	4	7
936	A:A:E309	A:A:I308	1.37	No	No	0	4	7
937	R:R:L792	R:R:N793	1.37	No	Yes	0	6	9
938	B:B:N35	B:B:N36	1.36	No	No	0	1	1
939	G:G:E47	G:G:K46	1.35	No	No	0	3	1
940	A:A:E299	A:A:L296	1.33	No	No	0	6	6
941	A:A:D295	A:A:Q294	1.31	No	No	0	9	6
942	B:B:D5	B:B:Q6	1.31	No	No	0	1	1
943	B:B:D20	B:B:Q17	1.31	No	No	0	2	4
944	R:R:F852	R:R:T851	1.3	Yes	No	0	9	5
945	A:A:E15	A:A:Q12	1.27	No	No	0	6	2
946	B:B:E3	B:B:Q6	1.27	No	No	0	5	1
947	B:B:E12	B:B:Q13	1.27	No	Yes	0	4	1
948	R:R:K729	R:R:R724	1.24	No	No	0	9	7
949	R:R:F790	R:R:L791	1.22	Yes	No	0	9	6
950	A:A:E314	A:A:R317	1.16	Yes	No	0	6	2
951	B:B:E130	B:B:R129	1.16	No	No	0	3	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:F219	6.1	5	0	8
2	A:A:F222	8.572	5	2	7
3	A:A:R228	6.0125	4	0	9
4	A:A:K233	7.204	5	1	9
5	A:A:W234	6.558	5	0	9
6	A:A:F238	9.0575	4	0	9
7	A:A:S251	4.93	4	19	9
8	A:A:F273	5.406	5	20	9
9	A:A:W277	10.212	5	20	6
10	A:A:W281	10.56	5	2	5
11	A:A:K293	7.3075	4	19	9
12	A:A:L297	3.335	4	0	8
13	A:A:F312	6.3575	4	16	8
14	A:A:E314	4.836	5	16	6
15	A:A:Y318	8.3875	4	0	6
16	A:A:E330	5.54	4	0	3
17	A:A:V334	5.6725	4	0	4
18	A:A:Y339	7.75	4	7	3
19	A:A:F340	10.904	5	16	7
20	A:A:R342	6.964	5	7	4
21	A:A:E344	7.795	4	16	5
22	A:A:F345	9.59	4	0	8
23	A:A:Y360	11.21	5	8	8
24	A:A:F363	10.924	5	7	5
25	A:A:T364	7.45	4	17	9
26	A:A:F376	7.5525	4	5	8
27	A:A:I383	4.085	4	5	8
28	A:A:R385	8.49833	6	8	5
29	A:A:H387	5.395	4	0	8
30	A:A:Y391	8.178	5	3	4
31	A:A:L393	3.25	5	3	8
32	A:A:L394	5.17833	6	8	8
33	B:B:Q13	4.2	4	21	1
34	B:B:L14	5.4425	4	21	8
35	B:B:L30	4.385	4	0	5
36	B:B:T34	6.33	4	6	5
37	B:B:I37	4.22	4	6	2
38	B:B:V40	4.0525	4	6	3
39	B:B:H54	8.81	6	4	9
40	B:B:K57	10.058	5	2	9
41	B:B:W63	7.825	4	0	7
42	B:B:W82	9.44714	7	4	9
43	B:B:D83	9.2825	4	4	8
44	B:B:T86	6.7975	4	4	6
45	B:B:K89	7.525	6	4	9
46	B:B:I93	5.405	4	13	7
47	B:B:L95	5.055	4	13	8
48	B:B:W99	10.175	6	2	9
49	B:B:M101	4.9425	4	0	9
50	B:B:Y105	4.058	5	0	6
51	B:B:Y111	6.2	4	0	4
52	B:B:Y124	5.40833	6	13	6
53	B:B:T128	4.5925	4	24	3
54	B:B:H142	8.69	4	1	9
55	B:B:Y145	7.784	5	1	8
56	B:B:F151	5.125	6	0	9
57	B:B:L152	4.185	4	0	3
58	B:B:T159	5.546	5	1	9
59	B:B:D163	10.2025	4	1	9
60	B:B:W169	8.24	6	1	8
61	B:B:D170	4.19	4	0	9
62	B:B:F180	8.056	5	10	7
63	B:B:H183	8.148	5	0	9
64	B:B:D186	6.68	4	1	9
65	B:B:F199	8.83	4	10	9
66	B:B:C204	6.2625	4	1	7
67	B:B:K209	8.588	5	10	6
68	B:B:W211	10.054	5	10	8
69	B:B:Q220	6.425	4	9	7
70	B:B:F222	8.91	4	9	8
71	B:B:H225	9.895	6	25	9
72	B:B:F235	8.3175	4	0	6
73	B:B:N237	8.075	4	0	5
74	B:B:F241	8.315	4	9	6
75	B:B:D246	5.9025	4	1	9
76	B:B:D247	6.89	5	25	9
77	B:B:R251	9.705	4	0	8
78	B:B:F253	7.088	5	9	6
79	B:B:D258	8.068	5	9	7
80	B:B:Y264	5.18333	6	0	5
81	B:B:R283	7.796	5	6	9
82	B:B:Y289	8.03286	7	26	7
83	B:B:D290	6.188	5	2	6
84	B:B:D298	8.4375	4	6	9
85	B:B:H311	10.0575	4	11	9
86	B:B:R314	13.108	5	2	8
87	B:B:W332	12.7483	6	2	9
88	B:B:D333	8.8125	4	11	9
89	B:B:K337	7.722	5	11	6
90	B:B:W339	10.568	5	11	9
91	G:G:V16	3.0275	4	0	7
92	G:G:D48	6.926	5	0	9
93	G:G:L51	4.798	5	0	6
94	G:G:P60	7.5925	4	22	9
95	G:G:F61	5.20167	6	22	8
96	L:L:?1	8.00667	6	0	0
97	R:R:Y642	6.3575	4	0	9
98	R:R:P653	8.71	4	3	9
99	R:R:L679	3.3275	4	29	8
100	R:R:H694	7.53167	6	15	9
101	R:R:Y695	5.958	5	12	9
102	R:R:F696	7.945	4	0	9
103	R:R:W703	9.8	4	12	9
104	R:R:E707	5.6375	4	3	9
105	R:R:H710	6.10833	6	3	9
106	R:R:F719	7.112	5	5	9
107	R:R:Y726	12.54	4	3	8
108	R:R:F730	7.7575	4	0	8
109	R:R:W735	7.82	5	12	9
110	R:R:P738	4.18	5	0	9
111	R:R:Y753	7.37833	6	15	9
112	R:R:F769	6.674	5	0	9
113	R:R:F778	6.0075	4	31	9
114	R:R:F790	6.236	5	30	9
115	R:R:N793	3.2175	4	0	9
116	R:R:F797	6.466	5	0	9
117	R:R:R817	8.9875	4	0	7
118	R:R:W838	9.015	6	14	9
119	R:R:F852	5.0525	4	0	9
120	R:R:F856	5.424	5	14	9
121	R:R:T861	3.3525	4	0	8
122	R:R:Q863	5.0175	4	14	9
123	R:R:F865	6.8175	4	27	7
124	R:R:F868	7.14	5	28	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:D76	B:B:L55	81.6647	12.21	No	No	0	9	6
2	A:A:Y37	B:B:L55	83.4095	5.86	No	No	0	4	6
3	A:A:R42	A:A:Y37	83.987	19.55	No	No	0	9	4
4	A:A:F222	A:A:R42	84.4375	5.34	Yes	No	0	7	9
5	A:A:F222	B:B:W99	85.8651	22.05	Yes	Yes	2	7	9
6	A:A:F238	B:B:W99	59.4447	10.02	Yes	Yes	0	9	9
7	A:A:F238	A:A:W234	60.6141	4.01	Yes	Yes	0	9	9
8	A:A:R231	A:A:W234	100	7	No	Yes	0	9	9
9	A:A:L272	A:A:R231	99.9566	8.5	No	No	0	8	9
10	A:A:F246	A:A:L272	99.9136	7.31	No	No	0	9	8
11	A:A:F246	A:A:L289	99.8262	3.65	No	No	0	9	9
12	A:A:F345	A:A:L289	99.7817	10.96	Yes	No	0	8	9
13	A:A:F345	A:A:L270	96.8993	10.96	Yes	No	0	8	6
14	A:A:E344	A:A:L270	96.8428	3.98	Yes	No	0	5	6
15	A:A:E344	A:A:F340	90.0901	12.83	Yes	Yes	16	5	7
16	A:A:F340	A:A:Y318	88.1134	12.38	Yes	Yes	0	7	6
17	A:A:D343	A:A:Y318	85.2189	11.49	No	Yes	0	3	6
18	A:A:D343	A:A:R342	84.9304	4.76	No	Yes	0	3	4
19	A:A:L346	A:A:R342	84.5537	6.07	No	Yes	7	4	4
20	A:A:L346	R:R:Q812	84.5558	9.32	No	No	0	4	8
21	A:A:Y358	R:R:Q812	84.4524	18.04	No	No	0	4	8
22	A:A:R385	A:A:Y358	77.8921	20.58	Yes	No	8	5	4
23	A:A:L394	A:A:R385	78.5244	4.86	Yes	Yes	8	8	5
24	A:A:L388	A:A:L394	52.3458	4.15	No	Yes	0	8	8
25	A:A:L388	R:R:L715	52.1637	5.54	No	No	0	8	8
26	R:R:L715	R:R:Q803	51.9837	3.99	No	No	0	8	9
27	A:A:Q384	R:R:Q803	51.4296	3.84	No	No	0	6	9
28	A:A:Q384	R:R:V718	51.1213	5.73	No	No	5	6	9
29	A:A:I383	R:R:V718	51.1817	4.61	Yes	No	5	8	9
30	A:A:H387	A:A:I383	52.7062	3.98	Yes	Yes	0	8	8
31	A:A:H387	A:A:Q390	52.4255	3.71	Yes	No	0	8	4
32	A:A:Q390	R:R:P653	40.3527	7.9	No	Yes	3	4	9
33	R:R:H710	R:R:P653	34.797	9.15	Yes	Yes	3	9	9
34	R:R:H710	R:R:Y726	17.3531	7.62	Yes	Yes	3	9	8
35	A:A:W234	B:B:Y145	80.9869	4.82	Yes	Yes	0	9	8
36	B:B:L117	B:B:W99	20.4625	6.83	No	Yes	0	9	9
37	B:B:L117	B:B:M101	20.4972	4.24	No	Yes	0	9	9
38	B:B:M101	B:B:Y145	22.1953	7.18	Yes	Yes	0	9	8
39	B:B:D186	B:B:Y145	74.2227	10.34	Yes	Yes	1	9	8
40	B:B:C204	B:B:D186	75.1394	7.78	Yes	Yes	1	7	9
41	A:A:R232	B:B:C204	10.3035	5.57	No	Yes	1	8	7
42	A:A:K233	A:A:R232	10.005	3.71	Yes	No	1	9	8
43	B:B:C204	B:B:D228	10.304	7.78	Yes	No	1	7	9
44	A:A:K233	B:B:D228	10.005	11.06	Yes	No	1	9	9
45	B:B:Q75	B:B:W99	13.7801	6.57	No	Yes	2	9	9
46	B:B:K57	B:B:Q75	13.2849	9.49	Yes	No	2	9	9
47	B:B:K57	B:B:W332	13.5263	19.73	Yes	Yes	2	9	9
48	B:B:D290	B:B:G272	12.0882	1.68	Yes	No	0	6	4
49	B:B:D246	B:B:G272	12.3921	1.68	Yes	No	0	9	4
50	A:A:F312	A:A:L266	13.1843	7.31	Yes	No	0	8	8
51	A:A:I341	A:A:L266	12.6968	7.14	No	No	0	8	8
52	A:A:I341	A:A:S250	12.2096	3.1	No	No	0	8	6
53	A:A:L297	A:A:S250	11.7226	6.01	Yes	No	0	8	6
54	A:A:F312	A:A:F340	10.4899	7.5	Yes	Yes	16	8	7
55	A:A:Q390	R:R:D651	11.9807	6.53	No	No	3	4	9
56	A:A:L394	R:R:Q822	26.6155	3.99	Yes	No	0	8	7
57	R:R:Q822	R:R:R825	26.1136	5.84	No	No	0	7	9
58	A:A:E392	R:R:R825	25.6122	11.63	No	No	0	6	9
59	A:A:E392	R:R:K875	25.3726	6.75	No	No	0	6	9
60	B:B:C204	B:B:G185	57.4255	3.92	Yes	No	0	7	5
61	B:B:G185	B:B:T184	57.1851	3.64	No	No	0	5	3
62	B:B:D205	B:B:T184	56.9596	10.12	No	No	0	9	3
63	B:B:D205	B:B:H183	34.3665	5.04	No	Yes	0	9	9
64	B:B:H183	B:B:K209	21.9706	14.41	Yes	Yes	0	9	6
65	B:B:K209	B:B:T221	27.8813	10.51	Yes	No	0	6	7
66	B:B:T221	G:G:E22	27.2912	8.47	No	No	0	7	9
67	B:B:D258	G:G:E22	26.7366	5.2	Yes	No	0	7	9
68	B:B:D258	B:B:R22	19.1838	13.1	Yes	No	0	7	6
69	B:B:I18	B:B:R22	18.5518	5.01	No	No	0	7	6
70	B:B:I18	G:G:A23	17.9193	3.25	No	No	0	7	8
71	B:B:L14	G:G:A23	17.2863	1.58	Yes	No	0	8	8
72	B:B:E10	B:B:L14	10.2601	7.95	No	Yes	21	8	8
73	B:B:D205	B:B:S207	22.384	8.83	No	No	0	9	5
74	B:B:K209	B:B:S207	21.8605	4.59	Yes	No	0	6	5
75	B:B:M325	G:G:P49	63.1537	8.39	No	No	0	5	7
76	G:G:D48	G:G:P49	61.5326	3.22	Yes	No	0	9	7
77	G:G:D48	G:G:L51	51.3514	9.5	Yes	Yes	0	9	6
78	B:B:R283	G:G:L51	41.259	7.29	Yes	Yes	0	9	6
79	B:B:I37	B:B:R283	19.108	3.76	Yes	Yes	6	2	9
80	B:B:I37	B:B:T34	18.0162	4.56	Yes	Yes	6	2	5
81	B:B:L30	B:B:T34	35.3133	4.42	Yes	Yes	0	5	5
82	B:B:L300	B:B:R283	18.7331	9.72	No	Yes	0	6	9
83	B:B:L300	B:B:T34	18.0167	10.32	No	Yes	0	6	5
84	B:B:L261	B:B:L30	27.2185	4.15	No	Yes	0	5	5
85	R:R:D651	R:R:S654	13.5263	8.83	No	No	0	9	9
86	R:R:S654	R:R:Y642	13.2952	3.82	No	Yes	0	9	9
87	R:R:I648	R:R:Y642	12.7524	9.67	No	Yes	0	8	9
88	R:R:I648	R:R:Q881	12.4436	4.12	No	No	0	8	9
89	R:R:K647	R:R:Q881	11.5141	8.14	No	No	0	9	9
90	B:B:D312	R:R:K647	11.2029	11.06	No	No	0	5	9
91	B:B:H54	B:B:W82	70.68	5.29	Yes	Yes	4	9	9
92	B:B:H54	B:B:S74	72.2806	12.55	Yes	No	0	9	9
93	B:B:L70	B:B:W82	69.3502	6.83	No	Yes	0	5	9
94	B:B:G162	B:B:Y145	25.9946	8.69	No	Yes	1	9	8
95	B:B:G162	B:B:S161	27.6592	3.71	No	No	1	9	9
96	B:B:H142	B:B:S161	25.5914	13.95	Yes	No	1	9	9
97	B:B:H142	B:B:T159	25.1188	6.85	Yes	Yes	1	9	9
98	B:B:C149	B:B:T159	12.2875	3.38	No	Yes	1	8	9
99	B:B:C149	B:B:T102	12.0437	5.07	No	No	0	8	8
100	B:B:C148	B:B:T102	11.772	3.38	No	No	0	6	8
101	B:B:C148	B:B:R150	10.6169	4.18	No	No	0	6	6
102	B:B:H62	B:B:R150	10.2822	15.8	No	No	0	6	6
103	B:B:L70	B:B:W63	68.8293	10.25	No	Yes	0	5	7
104	B:B:D323	B:B:M325	62.297	8.32	No	No	0	7	5
105	B:B:D323	B:B:T321	62.9156	7.23	No	No	0	7	7
106	B:B:T321	B:B:W63	63.5461	10.92	No	Yes	0	7	7
107	B:B:T159	B:B:W169	15.4234	9.7	Yes	Yes	1	9	8
108	B:B:I157	B:B:W169	12.7575	3.52	No	Yes	0	7	8
109	B:B:F180	B:B:T178	17.3541	5.19	Yes	No	0	7	4
110	B:B:F180	B:B:W211	14.6952	15.03	Yes	Yes	10	7	8
111	B:B:K209	B:B:W211	12.7565	6.96	Yes	Yes	10	6	8
112	B:B:D246	B:B:S227	26.1923	2.94	Yes	No	0	9	6
113	B:B:D247	B:B:S227	25.7259	2.94	Yes	No	0	9	6
114	B:B:D247	B:B:H225	16.3241	7.56	Yes	Yes	25	9	9
115	B:B:F253	B:B:R251	12.9041	4.28	Yes	Yes	0	6	8
116	B:B:L252	B:B:L261	24.2626	6.92	No	No	0	7	5
117	B:B:L252	B:B:Y264	23.5231	7.03	No	Yes	0	7	5
118	B:B:L285	B:B:Y264	19.768	4.69	No	Yes	0	6	5
119	B:B:F278	B:B:L285	18.2597	10.96	No	No	0	7	6
120	B:B:F235	B:B:F278	17.5048	10.72	Yes	No	0	6	7
121	B:B:L284	B:B:V296	17.1132	5.96	No	No	0	5	5
122	B:B:G306	B:B:V296	16.3742	1.84	No	No	0	4	5
123	B:B:G306	B:B:V307	15.6363	1.84	No	No	0	4	3
124	B:B:N293	B:B:V307	14.9027	4.43	No	No	0	5	3
125	B:B:D291	B:B:N293	13.4458	5.39	No	No	0	8	5
126	B:B:D291	B:B:Y289	11.9746	5.75	No	Yes	26	8	7
127	R:R:K875	R:R:V878	25.027	4.55	No	No	0	9	9
128	R:R:V878	R:R:W882	24.863	4.9	No	No	0	9	9
129	R:R:T641	R:R:W882	24.3716	13.34	No	No	0	9	9
130	R:R:C872	R:R:T641	24.0466	5.07	No	No	0	9	9
131	R:R:C872	R:R:F868	23.0081	6.98	No	Yes	28	9	9
132	R:R:F634	R:R:F868	22.79	18.22	No	Yes	0	9	9
133	R:R:F634	R:R:F865	22.248	10.72	No	Yes	0	9	7
134	R:R:F865	R:R:F866	26.11	5.36	Yes	No	27	7	9
135	R:R:F832	R:R:F866	25.858	21.43	No	No	0	6	9
136	R:R:F832	R:R:T837	24.4773	7.78	No	No	0	6	9
137	R:R:N860	R:R:T837	24.1996	5.85	No	No	0	9	9
138	R:R:F856	R:R:N860	14.9516	7.25	Yes	No	14	9	9
139	L:L:?1	R:R:F856	12.9696	8.48	Yes	Yes	0	0	9
140	R:R:H710	R:R:I656	15.3704	5.3	Yes	No	3	9	9
141	R:R:F730	R:R:I656	17.9921	3.77	Yes	No	0	8	9
142	R:R:F730	R:R:Y726	15.2943	14.44	Yes	Yes	0	8	8
143	R:R:F730	R:R:L706	30.6264	8.53	Yes	No	0	8	9
144	R:R:L706	R:R:W703	30.0936	6.83	No	Yes	0	9	9
145	R:R:W703	R:R:W735	28.4789	13.12	Yes	Yes	12	9	9
146	R:R:W735	R:R:Y695	22.4966	6.75	Yes	Yes	12	9	9
147	R:R:V742	R:R:Y695	19.2725	5.05	No	Yes	0	9	9
148	R:R:H694	R:R:V742	18.189	4.15	Yes	No	0	9	9
149	R:R:H694	R:R:Y753	11.1281	13.07	Yes	Yes	15	9	9
150	B:B:D76	B:B:S74	72.5709	7.36	No	No	0	9	9
151	A:A:K233	B:B:D246	18.1317	5.53	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:L620	5.51	0	Yes	No	0	9	0	1
L:L:?1	R:R:T624	5.87	0	Yes	No	0	9	0	1
L:L:?1	R:R:N763	12.29	0	Yes	No	0	5	0	1
L:L:?1	R:R:T765	10.26	0	Yes	No	0	5	0	1
L:L:?1	R:R:M853	5.63	0	Yes	No	0	8	0	1
L:L:?1	R:R:F856	8.48	0	Yes	Yes	0	9	0	1
R:R:T624	R:R:T861	4.71	0	No	Yes	9	8	1	2
R:R:P766	R:R:T765	5.25	0	No	No	5	5	2	1
R:R:F856	R:R:W838	4.01	14	Yes	Yes	9	9	1	2
R:R:N860	R:R:W838	24.86	14	No	Yes	9	9	2	2
R:R:A841	R:R:F856	4.16	0	No	Yes	9	9	2	1
R:R:F856	R:R:N860	7.25	14	Yes	No	9	9	1	2
R:R:L620	R:R:Y854	3.52	0	No	No	9	9	1	2
R:R:F840	R:R:F856	3.22	0	No	Yes	9	9	2	1
R:R:A844	R:R:M853	3.22	0	No	No	9	8	2	1
R:R:T621	R:R:T765	1.57	0	No	No	9	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
66.67	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
44.44	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
33.33	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
30.00	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
26.32	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
25.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
25.00	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
25.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
25.00	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
25.00	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
25.00	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
25.00	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
25.00	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
23.81	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
23.81	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
23.81	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
23.81	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
23.81	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
23.81	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
23.08	Single	5UEN	DU172	5UEN-A₁-DU172
23.08	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
23.08	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
23.08	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
22.73	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
22.73	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
22.73	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
22.73	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
22.73	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
22.73	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
22.22	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
22.22	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
21.74	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
21.74	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
21.74	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
21.74	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
21.43	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
21.43	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
21.05	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
21.05	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
20.83	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
20.83	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
20.83	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
20.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
20.00	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
20.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
20.00	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
20.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
20.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
20.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
20.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
19.23	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
19.05	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
19.05	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
19.05	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
18.75	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
18.75	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
18.75	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
18.75	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
18.75	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
18.75	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
18.52	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
18.52	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
18.52	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
18.52	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
18.18	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
18.18	Single	6LI0	C17	6LI0-GPR52-C17
18.18	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
18.18	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
18.18	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
18.18	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
18.18	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
18.18	Single	9B9Y	7DY	9B9Y-CB₁-7DY
18.18	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
18.18	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
18.18	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
17.65	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
17.39	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
17.39	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
17.39	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
17.39	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
17.39	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
17.39	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
17.39	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
16.67	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
16.67	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
16.67	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
16.67	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
16.67	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
16.67	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
16.67	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
16.67	Single	5U09	Taranabant	5U09-CB₁-Taranabant
16.67	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
16.67	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
16.67	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
16.67	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
16.67	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
16.67	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
16.67	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
16.67	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
16.67	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
16.67	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
16.67	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
16.67	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
16.67	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
16.67	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
16.67	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
16.67	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
16.67	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
16.67	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
16.67	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
16.67	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
16.67	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
16.67	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
16.67	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
16.67	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
16.67	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
16.67	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
16.67	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
16.67	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
16.67	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
16.67	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
16.67	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
16.67	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
16.67	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
16.67	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
16.67	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
16.67	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
16.67	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
16.00	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
16.00	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
16.00	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
16.00	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
15.79	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
15.79	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
15.79	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
15.79	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
15.79	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
15.79	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
15.79	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
15.38	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
15.38	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
15.38	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
15.38	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
15.38	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
15.38	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
15.38	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
15.38	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
15.38	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
15.38	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
15.38	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
15.38	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
15.38	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
15.38	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
15.38	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
15.38	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
15.38	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
15.38	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
15.38	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
15.38	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
15.38	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
15.38	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
15.38	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
15.38	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
15.38	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
15.38	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
15.38	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
15.38	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070-Cholesterol
15.38	Consensus	a2_off	Orthosteric Ligand	a2a_off
15.38	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
15.38	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
15.38	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
15.38	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
15.38	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
15.38	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
15.00	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
15.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
15.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
15.00	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
15.00	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
15.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
15.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
14.81	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
14.81	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
14.29	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
14.29	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
14.29	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
14.29	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
14.29	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
14.29	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
14.29	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
14.29	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
14.29	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
14.29	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
14.29	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
14.29	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
14.29	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
14.29	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
14.29	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
14.29	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
14.29	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
14.29	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
14.29	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
14.29	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
14.29	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
14.29	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
14.29	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
14.29	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
14.29	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
14.29	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
14.29	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
14.29	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
14.29	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
14.29	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
14.29	Single	8TH3	AT118-H Nanobody	8TH3-AT₁-AT118-H Nanobody
14.29	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
14.29	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
14.29	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
14.29	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
14.29	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
14.29	Single	9IMA	Talquetamab	9IMA-GPRC5D-Talquetamab
14.29	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
14.29	Consensus	a3_on	Orthosteric Ligand	a3a_on
14.29	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
14.29	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
14.29	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
14.29	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
14.29	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
14.29	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
14.29	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
14.29	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
14.29	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
14.29	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
13.79	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
13.79	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
13.79	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
13.79	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
13.64	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
13.64	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
13.64	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
13.64	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
13.64	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
13.64	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
13.64	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
13.64	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
13.64	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
13.64	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
13.64	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
13.64	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
13.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
13.33	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
13.33	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
13.33	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
13.33	Single	5N2S	PSB36	5N2S-A₁-PSB36
13.33	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
13.33	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
13.33	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
13.33	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
13.33	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
13.33	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
13.33	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
13.33	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
13.33	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
13.33	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
13.33	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
13.33	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
13.33	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/β1/γ2
13.33	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
13.33	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
13.33	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
13.33	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
13.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
13.33	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
13.33	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
13.33	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
13.33	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
13.33	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
13.33	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
13.33	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
13.33	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
13.33	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
13.33	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
13.33	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go1/β1/γ2
13.33	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
13.33	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
13.33	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
13.33	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
13.33	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
13.33	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
13.33	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
13.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
13.33	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
13.33	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
13.33	Consensus	ep_off	Orthosteric Ligand	ep4_off
13.33	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
13.33	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
13.33	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
13.04	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
13.04	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
13.04	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
13.04	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
13.04	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
13.04	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
13.04	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
12.50	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
12.50	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
12.50	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
12.50	Single	5TZR	MK8666	5TZR-FFA1-MK8666
12.50	Single	5V56	TC114	5V56-SMO-TC114
12.50	Single	5V57	TC114	5V57-SMO-TC114
12.50	Single	5XR8	AM841	5XR8-CB₁-AM841
12.50	Single	5XRA	AM11542	5XRA-CB₁-AM11542
12.50	Single	6FJ3	PTH	6FJ3-PTH1-PTH
12.50	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
12.50	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
12.50	Single	6OS1	TRV026	6OS1-AT₁-TRV026
12.50	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
12.50	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
12.50	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
12.50	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
12.50	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
12.50	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
12.50	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
12.50	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
12.50	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
12.50	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
12.50	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
12.50	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
12.50	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
12.50	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
12.50	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
12.50	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
12.50	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
12.50	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
12.50	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
12.50	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
12.50	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
12.50	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
12.50	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
12.50	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
12.50	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
12.50	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
12.50	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
12.50	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
12.50	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
12.50	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
12.50	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
12.50	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
12.50	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
12.50	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
12.50	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
12.50	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
12.50	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
12.50	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
12.50	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
12.50	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
12.50	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	a2_on	Orthosteric Ligand	a2b_on
12.50	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
12.50	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
12.50	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
12.50	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
12.50	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
12.50	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
12.50	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
12.50	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
12.50	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
12.50	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
12.50	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
12.50	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
12.50	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
12.50	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
12.50	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
12.50	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
12.50	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
12.50	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
12.00	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
12.00	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
12.00	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
11.76	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
11.76	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
11.76	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
11.76	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
11.76	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
11.76	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
11.76	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
11.76	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
11.76	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
11.76	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
11.76	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
11.76	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
11.76	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
11.76	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
11.76	Single	6OS2	TRV026	6OS2-AT₁-TRV026
11.76	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
11.76	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
11.76	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
11.76	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
11.76	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
11.76	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
11.76	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
11.76	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
11.76	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
11.76	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
11.76	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
11.76	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
11.76	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
11.76	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
11.76	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
11.76	Single	8JWY	2-118	8JWY-A_2A-2-118
11.76	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
11.76	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
11.76	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
11.76	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
11.76	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
11.76	Single	8XJN	Cloprosetnol	8XJN-TP-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	8XQJ	JN241	8XQJ-Apelin-JN241
11.76	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
11.76	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
11.76	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
11.76	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
11.76	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
11.76	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116-Cholesterol
11.76	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
11.76	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
11.76	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
11.76	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
11.76	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
11.76	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
11.76	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
11.76	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
11.76	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
11.76	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
11.76	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
11.76	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
11.76	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
11.76	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
11.76	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
11.76	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
11.76	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
11.76	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
11.76	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
11.54	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
11.54	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
11.54	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
11.54	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.54	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
11.54	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
11.54	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
11.54	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
11.11	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
11.11	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
11.11	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
11.11	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
11.11	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
11.11	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
11.11	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
11.11	Single	7EZC	UKA	7EZC-A_2A-UKA
11.11	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
11.11	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
11.11	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
11.11	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
11.11	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
11.11	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
11.11	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
11.11	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
11.11	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
11.11	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
11.11	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
11.11	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
11.11	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
11.11	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
11.11	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
11.11	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
11.11	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
11.11	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
11.11	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
11.11	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
11.11	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
11.11	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
11.11	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
11.11	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
11.11	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
11.11	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
11.11	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
11.11	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
11.11	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
11.11	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
11.11	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
11.11	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
11.11	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
11.11	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
11.11	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
11.11	Consensus	tp_on	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
10.71	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
10.71	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
10.71	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
10.53	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
10.53	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
10.53	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
10.53	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
10.53	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
10.53	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
10.53	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
10.53	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
10.53	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
10.53	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
10.53	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
10.53	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
10.53	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
10.53	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
10.53	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.53	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
10.53	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
10.53	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
10.53	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
10.53	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
10.53	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
10.53	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
10.53	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
10.53	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
10.53	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
10.53	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
10.53	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
10.53	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
10.53	Single	8XQJ	JN241	8XQJ-Apelin-JN241
10.53	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
10.53	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
10.53	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
10.53	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
10.53	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
10.53	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
10.53	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
10.53	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
10.53	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
10.53	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
10.00	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
10.00	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
10.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
10.00	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
10.00	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
10.00	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
10.00	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
10.00	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
10.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
10.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
10.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
10.00	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
10.00	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
10.00	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
10.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
10.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
10.00	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
10.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
10.00	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.00	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
10.00	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
10.00	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
10.00	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
10.00	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
10.00	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/β1/γ2
10.00	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
10.00	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
10.00	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
10.00	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
10.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
10.00	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
10.00	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.00	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.00	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
10.00	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
10.00	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
10.00	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
10.00	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
10.00	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
10.00	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
10.00	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
10.00	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
10.00	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
10.00	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
10.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
10.00	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.68	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.52	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
9.52	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
9.52	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
9.52	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
9.52	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
9.52	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
9.52	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
9.52	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
9.52	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
9.52	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
9.52	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
9.52	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
9.52	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
9.52	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
9.52	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
9.52	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
9.52	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
9.52	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
9.52	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
9.52	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
9.52	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
9.52	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
9.52	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
9.52	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
9.52	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
9.52	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
9.52	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
9.52	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
9.52	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
9.52	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
9.52	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
9.52	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
9.38	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
9.38	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
9.09	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
9.09	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
9.09	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
9.09	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
9.09	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
9.09	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
9.09	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
9.09	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
9.09	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
9.09	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
9.09	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
9.09	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
9.09	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
9.09	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
9.09	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
9.09	Single	7F61	Cholesterol	7F61-H₃-PF-03654746-Cholesterol
9.09	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
9.09	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
9.09	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
9.09	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
9.09	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
9.09	Single	7V6A	-	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
9.09	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
9.09	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
9.09	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
9.09	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
9.09	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
9.09	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
9.09	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
9.09	Single	8J6Q	Compound 9n	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
9.09	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
9.09	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
9.09	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
9.09	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
9.09	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.09	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.09	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
9.09	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
9.09	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
9.09	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
9.09	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
9.09	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
9.09	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
9.09	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
9.09	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
9.09	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
9.09	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
9.09	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
9.09	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
9.09	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
9.09	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
9.09	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
8.82	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
8.70	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
8.70	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
8.70	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
8.70	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
8.70	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
8.70	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.70	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
8.70	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
8.70	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
8.70	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
8.70	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
8.70	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
8.70	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
8.70	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
8.70	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
8.70	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
8.70	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
8.70	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
8.70	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
8.70	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
8.70	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
8.33	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
8.33	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
8.33	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
8.33	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
8.33	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
8.33	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
8.33	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
8.33	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
8.33	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
8.33	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
8.33	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
8.33	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
8.33	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
8.33	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
8.33	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
8.33	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
8.33	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
8.33	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
8.33	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
8.33	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
8.33	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
8.33	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
8.33	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
8.33	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
8.33	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
8.33	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
8.33	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
8.33	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
8.33	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
8.33	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
8.33	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/β1/γ2
8.33	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
8.33	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
8.33	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
8.33	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
8.33	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
8.33	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
8.33	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
8.33	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
8.33	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
8.33	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
8.33	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
8.33	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
8.33	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
8.33	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
8.33	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
8.33	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
8.33	Single	8YRG	Fospropofol	8YRG-MRGPRX4-Fospropofol-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
8.33	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
8.33	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
8.33	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
8.33	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
8.33	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
8.33	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
8.33	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
8.33	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
8.33	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
8.33	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
8.33	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
8.33	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
8.33	Consensus	neurotensin_off	Orthosteric Ligand	nts1_off
8.33	Consensus	nts1_off	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
8.33	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
8.33	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
8.00	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
8.00	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
8.00	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
8.00	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
8.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
8.00	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
8.00	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
8.00	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
8.00	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
8.00	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
8.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
8.00	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
8.00	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
8.00	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
8.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
7.89	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
7.69	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
7.69	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
7.69	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
7.69	Single	6AKX	A4R	6AKX-CCR5-A4R
7.69	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
7.69	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
7.69	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
7.69	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
7.69	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
7.69	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
7.69	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
7.69	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
7.69	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
7.69	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
7.69	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
7.69	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
7.69	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
7.69	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
7.69	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
7.69	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
7.69	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
7.69	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
7.69	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
7.69	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
7.69	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
7.69	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
7.69	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
7.69	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
7.69	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
7.69	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
7.69	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
7.69	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
7.69	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
7.69	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.69	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
7.69	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
7.69	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
7.69	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
7.69	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
7.69	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
7.69	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
7.69	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
7.69	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
7.69	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
7.69	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
7.69	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
7.69	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
7.69	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
7.69	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
7.69	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
7.69	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.69	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
7.69	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
7.69	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
7.69	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
7.69	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
7.69	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.69	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
7.69	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
7.69	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.69	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.69	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
7.69	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
7.69	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
7.69	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
7.69	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.69	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.41	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
7.41	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
7.41	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
7.41	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
7.41	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
7.41	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
7.41	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
7.41	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
7.41	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
7.41	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
7.41	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
7.41	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
7.41	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
7.41	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
7.41	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
7.14	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
7.14	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
7.14	Single	3REY	XAC	3REY-A_2A-XAC
7.14	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
7.14	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
7.14	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
7.14	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
7.14	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
7.14	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
7.14	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
7.14	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
7.14	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
7.14	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
7.14	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
7.14	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
7.14	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
7.14	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
7.14	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
7.14	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
7.14	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
7.14	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
7.14	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
7.14	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
7.14	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
7.14	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
7.14	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
7.14	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
7.14	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
7.14	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
7.14	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
7.14	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
7.14	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
7.14	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
7.14	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
7.14	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
7.14	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
7.14	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
7.14	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
7.14	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
7.14	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
7.14	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
7.14	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
7.14	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
7.14	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
7.14	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
7.14	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
7.14	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
7.14	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
7.14	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
7.14	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
7.14	Single	8K9L	Damgo	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
7.14	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
7.14	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
7.14	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
7.14	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
7.14	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
7.14	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
7.14	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
7.14	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
7.14	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
7.14	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
7.14	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100-Cholesterol
7.14	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
7.14	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
7.14	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
7.14	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
7.14	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
7.14	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
7.14	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
7.14	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.14	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
7.14	Consensus	hca_on	Orthosteric Ligand	hca2_on
7.14	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
7.14	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
7.14	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
7.14	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
7.14	Consensus	sensory_off	Orthosteric Ligand	opsins_off
6.90	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
6.90	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
6.90	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
6.90	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
6.90	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
6.67	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
6.67	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
6.67	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
6.67	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
6.67	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
6.67	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
6.67	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
6.67	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
6.67	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
6.67	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
6.67	Single	6D27	CAY10471	6D27-DP₂-CAY10471
6.67	Single	6GPS	MK0812	6GPS-CCR2-MK0812
6.67	Single	6IIV	Daltroban	6IIV-TP-Daltroban
6.67	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
6.67	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
6.67	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
6.67	Single	6PS1	Timolol	6PS1-β₂-Timolol
6.67	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
6.67	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
6.67	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
6.67	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
6.67	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
6.67	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
6.67	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
6.67	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
6.67	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
6.67	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
6.67	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
6.67	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
6.67	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
6.67	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
6.67	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
6.67	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
6.67	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
6.67	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
6.67	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
6.67	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
6.67	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
6.67	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
6.67	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
6.67	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
6.67	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
6.67	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
6.67	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
6.67	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
6.67	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
6.67	Single	8JXR	LSD	8JXR-D₁-LSD
6.67	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
6.67	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
6.67	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
6.67	Single	8T1W	CVN424	8T1W-GPR6-CVN424
6.67	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.67	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.67	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.67	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.67	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.67	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
6.67	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
6.67	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
6.67	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
6.67	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
6.67	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
6.67	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
6.67	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
6.67	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
6.67	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
6.67	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
6.67	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
6.67	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
6.67	Consensus	cck_off	Orthosteric Ligand	ccka_off
6.67	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
6.67	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
6.67	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
6.67	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
6.67	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
6.67	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
6.67	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
6.67	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
6.67	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
6.67	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
6.45	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
6.45	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
6.25	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
6.25	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
6.25	Single	5C1M	BU72	5C1M-μ-BU72
6.25	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
6.25	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
6.25	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
6.25	Single	6GPX	MK0812	6GPX-CCR2-MK0812
6.25	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
6.25	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
6.25	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
6.25	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
6.25	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
6.25	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
6.25	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
6.25	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
6.25	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
6.25	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
6.25	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
6.25	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
6.25	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
6.25	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
6.25	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
6.25	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
6.25	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
6.25	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
6.25	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
6.25	Single	7W41	PD176252	7W41-BB₂-PD176252
6.25	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
6.25	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
6.25	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
6.25	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
6.25	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
6.25	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
6.25	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
6.25	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
6.25	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
6.25	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
6.25	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
6.25	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
6.25	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
6.25	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
6.25	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
6.25	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
6.25	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
6.25	Single	8WGB	W9R	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
6.25	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
6.25	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
6.25	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
6.25	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
6.25	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
6.25	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go1/β1/γ2
6.25	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
6.25	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
6.25	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
6.25	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
6.25	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
6.25	Consensus	dp_off	Orthosteric Ligand	dp2_off
6.25	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
6.25	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
6.25	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
6.25	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
6.25	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
6.25	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
6.25	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
6.25	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
5.88	Single	2YDV	NECA	2YDV-A_2A-NECA
5.88	Single	3P0G	BI167107	3P0G-β₂-BI167107
5.88	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
5.88	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
5.88	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
5.88	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
5.88	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
5.88	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
5.88	Single	5G53	NECA	5G53-A_2A-NECA-Gs
5.88	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
5.88	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.88	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
5.88	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
5.88	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
5.88	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.88	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
5.88	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.88	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.88	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
5.88	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
5.88	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
5.88	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
5.88	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
5.88	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
5.88	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
5.88	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
5.88	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
5.88	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
5.88	Single	8E0G	BU72	8E0G-μ-BU72
5.88	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
5.88	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
5.88	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
5.88	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
5.88	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
5.88	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
5.88	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
5.88	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
5.88	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
5.88	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
5.88	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
5.88	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
5.88	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.88	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
5.88	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
5.88	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
5.88	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
5.88	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
5.88	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
5.88	Single	9GE2	ML184	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
5.88	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
5.88	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.88	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.88	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.88	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.88	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.88	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
5.88	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
5.88	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.88	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
5.88	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
5.88	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.88	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.88	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
5.56	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
5.56	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
5.56	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
5.56	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
5.56	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
5.56	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
5.56	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
5.56	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.56	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
5.56	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
5.56	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
5.56	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
5.56	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
5.56	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
5.56	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
5.56	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
5.56	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.56	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
5.56	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
5.56	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
5.56	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
5.56	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
5.56	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
5.56	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.56	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
5.56	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
5.56	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
5.56	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
5.56	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.56	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
5.56	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
5.56	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
5.56	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
5.56	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
5.56	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
5.56	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
5.56	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
5.56	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
5.56	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
5.56	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
5.56	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
5.56	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
5.56	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.56	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
5.56	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.56	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
5.56	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
5.56	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.56	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
5.56	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
5.56	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.56	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.56	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.56	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
5.26	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
5.26	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
5.26	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
5.26	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
5.26	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
5.26	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
5.26	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
5.26	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
5.26	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
5.26	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
5.26	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
5.26	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
5.26	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
5.26	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
5.26	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
5.26	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
5.26	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
5.26	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
5.26	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
5.26	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
5.26	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
5.26	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
5.26	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
5.26	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
5.26	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
5.26	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
5.26	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
5.26	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
5.26	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
5.26	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
5.26	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
5.26	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
5.26	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
5.26	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.26	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
5.26	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
5.26	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
5.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
5.00	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
5.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
5.00	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
5.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
5.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
5.00	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
5.00	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
5.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
5.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
5.00	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
5.00	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
5.00	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
5.00	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
5.00	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
5.00	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.76	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
4.76	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
4.76	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
4.76	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
4.76	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
4.76	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
4.76	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.76	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
4.76	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.76	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.76	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.76	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.76	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
4.76	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
4.76	Single	8WKY	PG-934	8WKY-MC₄-PG-934
4.76	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.76	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.76	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.76	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
4.76	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.76	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.76	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
4.55	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
4.55	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.55	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.55	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
4.55	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
4.55	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.55	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
4.55	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
4.55	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
4.55	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
4.55	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
4.55	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.35	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
4.35	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
4.35	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
4.35	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
4.35	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
4.35	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
4.35	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
4.17	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
4.17	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
4.17	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
4.17	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
4.17	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
4.17	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
4.17	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
4.17	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
4.17	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
4.17	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
4.17	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
4.17	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
4.17	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
4.17	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
4.17	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
4.00	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
4.00	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.70	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
3.70	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
3.57	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
3.57	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
3.45	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.45	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.45	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
3.45	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
3.45	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.33	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1

PDB Summary
PDB	7XKD
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRG2
Species	Mus Musculus
Ligand	Beta-Hydroxyandrosterone
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	2.4
Date	2022-08-10
D.O.I.	10.1038/s41589-022-01084-6

Net Summary
I_min	3.64
Number of Linked Nodes	841
Number of Links	951
Number of Hubs	124
Number of Links mediated by Hubs	491
Number of Communities	31
Number of Nodes involved in Communities	176
Number of Links involved in Communities	222

Path Summary
Number Of Nodes in MetaPath	152
Number Of Links MetaPath	151
Number of Shortest Paths	802462
Length Of Smallest Path	3
Average Path Length	34.151
Length of Longest Path	81
Minimum Path Strength	1.29
Average Path Strength	7.7782
Maximum Path Strength	23.36
Minimum Path Correlation	0.7
Average Path Correlation	0.977367
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.17391
Average % Of Corr. Nodes	43.1987
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.1511
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • cell surface receptor signaling pathway • response to stimulus • signaling • biological regulation • cellular process • signal transduction • cell communication • apical part of cell • plasma membrane region • apical plasma membrane • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to nitrogen compound • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	AND
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	AND
Name	Prasterone
Synonyms	3-beta-hydroxy-5-androsten-17-one
Identifier
Formula	C19 H28 O2
Molecular Weight	288.424
SMILES
PubChem	5881
Formal Charge	0
Total Atoms	49
Total Chiral Atoms	6
Total Bonds	52
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>7XKD_Chain_A E D Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A G E S G K N T I V K S G I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V A S S T N R L Q A A L K L F D S I W N N K W L R D T S V I L F L N K Q D L L A E K V L A G K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N I R R V F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>7XKD_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>7XKD_Chain_G S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q8CJ12
Sequence	>7XKD_Chain_R Q M M A L T F I T Y I G C G L S S I F L S V T L V T Y I A F E K I R R D Y P S K I L I Q L C A A L L L L N L I F L L D S W I A L Y N T R G F C I A V A V F L H Y F L L V S F T W M G L E A F H M Y L A L V K V F N T Y I R K Y I L K F C I V G W G I P A V V V S I V L T I S P D N Y G I G N G T P D D F C W I N S N V V F Y I T V V G Y F C V I F L L N V S M F I V V L V Q L C R I K K K K Q L G A Q R K T S I Q D L R S I A G L T F L L G I T W G F A F F A W G V N V T F M Y L F A I F N T L Q G F F I F I F Y C A A K E N V R K Q W R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7YP7	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-	Gs/β1/γ2	3.1	2022-08-24	10.1038/s41589-022-01084-6
	7YP7 (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-		3.1	2022-08-24	10.1038/s41589-022-01084-6
	7XKE	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-08-10	10.1038/s41589-022-01084-6
	7XKE (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-		2.9	2022-08-10	10.1038/s41589-022-01084-6
	7XKF	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-	Gs/β1/γ2	2.4	2022-08-10	10.1038/s41589-022-01084-6
	7XKF (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-		2.4	2022-08-10	10.1038/s41589-022-01084-6
	7XKD	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-	Gs/β1/γ2	2.4	2022-08-10	10.1038/s41589-022-01084-6
	7XKD (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	β-Hydroxyandrosterone	-		2.4	2022-08-10	10.1038/s41589-022-01084-6
	7WUI	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	IP15	-	chim(NtGi1-Gs)/β1/γ2	3.1	2022-04-27	10.1038/s41586-022-04590-8
	7WUI (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	IP15	-		3.1	2022-04-27	10.1038/s41586-022-04590-8
	7WUQ	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-	Gs/β1/γ2	2.9	2022-04-27	10.1038/s41586-022-04590-8
	7WUQ (No Gprot)	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-		2.9	2022-04-27	10.1038/s41586-022-04590-8

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