psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:V2	L:L:Y27	6.31	Yes	Yes	1	0	0
2	L:L:R98	L:L:V2	6.54	Yes	Yes	1	0	0
3	L:L:V2	L:L:Y107	20.19	Yes	Yes	1	0	0
4	L:L:L4	L:L:Y27	3.52	No	Yes	0	0	0
5	L:L:Q6	L:L:W36	3.29	Yes	Yes	15	0	0
6	L:L:C96	L:L:Q6	6.1	Yes	Yes	15	0	0
7	L:L:G109	L:L:Q6	3.29	No	Yes	0	0	0
8	L:L:Q110	L:L:Q6	5.12	No	Yes	0	0	0
9	L:L:G111	L:L:Q6	3.29	No	Yes	0	0	0
10	L:L:Q6	L:L:T112	7.09	Yes	No	0	0	0
11	L:L:G8	L:L:S7	3.71	No	No	0	0	0
12	L:L:E10	L:L:K12	4.05	No	No	0	0	0
13	L:L:T115	L:L:V11	4.76	No	No	0	0	0
14	L:L:P152	L:L:V11	3.53	Yes	No	0	0	0
15	L:L:K12	L:L:V18	7.59	No	No	0	0	0
16	L:L:K13	L:L:P14	3.35	No	No	0	0	0
17	L:L:P14	L:L:V116	3.53	No	No	0	0	0
18	L:L:P14	L:L:S118	3.56	No	No	0	0	0
19	L:L:E82	L:L:S17	4.31	No	No	0	0	0
20	L:L:L86	L:L:V18	4.47	Yes	No	0	0	0
21	L:L:V114	L:L:V18	4.81	No	No	0	0	0
22	L:L:K19	L:L:Y80	4.78	No	Yes	0	0	0
23	L:L:E82	L:L:K19	10.8	No	No	0	0	0
24	L:L:V20	L:L:W36	4.9	No	Yes	0	0	0
25	L:L:T112	L:L:V20	4.76	No	No	0	0	0
26	L:L:C22	L:L:C96	7.28	No	Yes	0	0	0
27	L:L:K23	L:L:T78	6.01	No	No	0	0	0
28	L:L:A24	L:L:Y27	4	No	Yes	0	0	0
29	L:L:G26	L:L:S25	3.71	No	No	0	0	0
30	L:L:Y27	L:L:Y32	5.96	Yes	Yes	1	0	0
31	L:L:R98	L:L:Y27	11.32	Yes	Yes	1	0	0
32	L:L:F29	L:L:P53	8.67	No	No	1	0	0
33	L:L:F29	L:L:T72	5.19	No	Yes	1	0	0
34	L:L:F29	L:L:S77	10.57	No	No	0	0	0
35	L:L:T30	L:L:Y54	3.75	No	No	1	0	0
36	L:L:T30	R:R:Q87	7.09	No	Yes	1	0	4
37	L:L:G31	R:R:Q87	4.93	No	Yes	0	0	4
38	L:L:R98	L:L:Y32	18.52	Yes	Yes	1	0	0
39	L:L:Y32	R:R:E83	4.49	Yes	No	0	0	3
40	L:L:Y32	R:R:N85	9.3	Yes	No	0	0	6
41	L:L:L50	L:L:T33	5.9	Yes	No	1	0	0
42	L:L:N52	L:L:T33	5.85	Yes	No	1	0	0
43	L:L:T33	R:R:Q86	5.67	No	Yes	1	0	4
44	L:L:C96	L:L:M34	3.24	Yes	No	0	0	0
45	L:L:M34	L:L:R98	3.72	No	Yes	0	0	0
46	L:L:N35	L:L:W47	13.56	Yes	Yes	1	0	0
47	L:L:L50	L:L:N35	5.49	Yes	Yes	1	0	0
48	L:L:L105	L:L:N35	5.49	Yes	Yes	1	0	0
49	L:L:N35	N:N:Y96	6.98	Yes	Yes	1	0	0
50	L:L:M70	L:L:W36	5.82	Yes	Yes	0	0	0
51	L:L:M81	L:L:W36	13.96	No	Yes	0	0	0
52	L:L:C96	L:L:W36	7.84	Yes	Yes	15	0	0
53	L:L:V37	L:L:W108	6.13	No	Yes	0	0	0
54	L:L:V37	N:N:F98	5.24	No	No	0	0	0
55	L:L:E46	L:L:R38	11.63	No	Yes	0	0	0
56	L:L:M48	L:L:R38	8.69	No	Yes	5	0	0
57	L:L:L64	L:L:R38	3.64	No	Yes	5	0	0
58	L:L:D90	L:L:R38	7.15	Yes	Yes	5	0	0
59	L:L:A92	L:L:R38	4.15	No	Yes	5	0	0
60	L:L:R38	L:L:Y94	9.26	Yes	Yes	5	0	0
61	L:L:L45	L:L:Q39	9.32	Yes	Yes	1	0	0
62	L:L:Q39	L:L:Y95	4.51	Yes	Yes	1	0	0
63	L:L:Q39	N:N:Q38	11.52	Yes	No	1	0	0
64	L:L:Q39	N:N:Y87	4.51	Yes	Yes	1	0	0
65	L:L:L45	N:N:P44	3.28	Yes	Yes	1	0	0
66	L:L:L45	N:N:Y87	7.03	Yes	Yes	1	0	0
67	L:L:L45	N:N:F98	14.61	Yes	No	0	0	0
68	L:L:E46	L:L:K63	6.75	No	No	0	0	0
69	L:L:G49	L:L:W47	9.85	No	Yes	0	0	0
70	L:L:L50	L:L:W47	4.56	Yes	Yes	1	0	0
71	L:L:W47	N:N:Y96	16.4	Yes	Yes	1	0	0
72	L:L:L64	L:L:M48	4.24	No	No	5	0	0
73	L:L:M48	L:L:Y94	4.79	No	Yes	5	0	0
74	L:L:G49	L:L:M70	3.49	No	Yes	0	0	0
75	L:L:L50	L:L:N59	4.12	Yes	No	0	0	0
76	L:L:L50	N:N:Y94	5.86	Yes	Yes	1	0	0
77	L:L:I51	L:L:T58	4.56	No	No	0	0	0
78	L:L:I51	L:L:M70	4.37	No	Yes	0	0	0
79	L:L:I51	L:L:T72	7.6	No	Yes	0	0	0
80	L:L:N52	L:L:P53	4.89	Yes	No	1	0	0
81	L:L:N52	L:L:N55	4.09	Yes	No	0	0	0
82	L:L:N52	R:R:Q86	11.88	Yes	Yes	1	0	4
83	L:L:P53	L:L:T72	6.99	No	Yes	1	0	0
84	L:L:Y54	R:R:Q87	5.64	No	Yes	1	0	4
85	L:L:D57	L:L:N55	4.04	No	No	0	0	0
86	L:L:T58	L:L:Y60	16.23	No	Yes	0	0	0
87	L:L:V68	L:L:Y60	10.09	No	Yes	0	0	0
88	L:L:M70	L:L:Y60	13.17	Yes	Yes	0	0	0
89	L:L:Q62	L:L:Q65	11.52	No	No	0	0	0
90	L:L:L64	L:L:R67	3.64	No	Yes	5	0	0
91	L:L:L83	L:L:R67	3.64	No	Yes	5	0	0
92	L:L:R67	L:L:R87	11.73	Yes	No	0	0	0
93	L:L:D90	L:L:R67	11.91	Yes	Yes	5	0	0
94	L:L:R84	L:L:T69	9.06	No	No	0	0	0
95	L:L:T71	L:L:Y80	3.75	No	Yes	0	0	0
96	L:L:D73	L:L:S75	7.36	No	No	16	0	0
97	L:L:D73	L:L:T76	10.12	No	No	16	0	0
98	L:L:S75	L:L:T76	4.8	No	No	16	0	0
99	L:L:T76	L:L:T78	4.71	No	No	0	0	0
100	L:L:T78	L:L:Y80	11.24	No	Yes	0	0	0
101	L:L:M81	L:L:Y94	3.59	No	Yes	0	0	0
102	L:L:E82	L:L:R84	3.49	No	No	0	0	0
103	L:L:L83	L:L:L86	4.15	No	Yes	5	0	0
104	L:L:D90	L:L:L83	4.07	Yes	No	5	0	0
105	L:L:D90	L:L:L86	5.43	Yes	Yes	5	0	0
106	L:L:L86	L:L:V116	7.45	Yes	No	0	0	0
107	L:L:D89	L:L:R87	11.91	No	No	0	0	0
108	L:L:D89	L:L:D90	6.65	No	Yes	0	0	0
109	L:L:T115	L:L:T91	4.71	No	No	0	0	0
110	L:L:A92	L:L:Y94	5.34	No	Yes	5	0	0
111	L:L:V93	L:L:Y95	8.83	No	Yes	0	0	0
112	L:L:V114	L:L:Y94	6.31	No	Yes	0	0	0
113	L:L:W108	L:L:Y95	6.75	Yes	Yes	1	0	0
114	L:L:G111	L:L:Y95	5.79	No	Yes	0	0	0
115	L:L:Y95	N:N:P44	4.17	Yes	Yes	1	0	0
116	L:L:A97	L:L:L105	6.3	No	Yes	1	0	0
117	L:L:A97	L:L:W108	7.78	No	Yes	1	0	0
118	L:L:D106	L:L:R98	11.91	Yes	Yes	1	0	0
119	L:L:R98	L:L:Y107	6.17	Yes	Yes	1	0	0
120	L:L:L101	R:R:L84	6.92	No	No	0	0	4
121	L:L:R102	R:R:L84	9.72	Yes	No	0	0	4
122	L:L:R102	R:R:P163	5.76	Yes	No	1	0	6
123	L:L:R102	R:R:P235	5.76	Yes	Yes	1	0	4
124	L:L:R102	R:R:D238	7.15	Yes	Yes	1	0	8
125	L:L:R102	R:R:D239	10.72	Yes	No	0	0	9
126	L:L:V103	N:N:Y49	12.62	No	Yes	1	0	0
127	L:L:V103	N:N:Y55	10.09	No	Yes	1	0	0
128	L:L:A104	N:N:Y91	4	No	Yes	0	0	0
129	L:L:L105	L:L:W108	7.97	Yes	Yes	1	0	0
130	L:L:L105	N:N:Y36	5.86	Yes	No	1	0	0
131	L:L:D106	L:L:Y107	9.2	Yes	Yes	1	0	0
132	L:L:D106	N:N:R46	5.96	Yes	Yes	1	0	0
133	L:L:D106	N:N:Y55	4.6	Yes	Yes	1	0	0
134	L:L:Y107	N:N:R46	4.12	Yes	Yes	1	0	0
135	L:L:W108	N:N:Y36	3.86	Yes	No	1	0	0
136	L:L:W108	N:N:P44	12.16	Yes	Yes	1	0	0
137	L:L:L113	L:L:T115	4.42	No	No	0	0	0
138	L:L:F151	L:L:S117	5.28	Yes	No	0	0	0
139	L:L:A119	L:L:F151	5.55	No	Yes	0	0	0
140	L:L:P152	L:L:T121	3.5	Yes	No	0	0	0
141	L:L:K122	L:L:L180	7.05	No	No	0	0	0
142	L:L:G123	L:L:P124	4.06	No	No	0	0	0
143	L:L:G123	L:L:S208	3.71	No	No	0	0	0
144	L:L:H205	L:L:P124	10.68	Yes	No	0	0	0
145	L:L:P124	L:L:T210	8.74	No	No	0	0	0
146	L:L:V126	L:L:V203	6.41	No	No	0	0	0
147	L:L:V126	L:L:V212	9.62	No	No	0	0	0
148	L:L:K214	L:L:V126	4.55	No	No	0	0	0
149	L:L:F127	N:N:Q124	23.42	No	Yes	0	0	0
150	L:L:K214	L:L:P128	3.35	No	No	0	0	0
151	L:L:P128	L:L:V216	5.3	No	No	0	0	0
152	L:L:P128	N:N:S121	7.13	No	No	0	0	0
153	L:L:G144	L:L:L129	5.13	No	Yes	0	0	0
154	L:L:L129	L:L:L146	4.15	Yes	No	0	0	0
155	L:L:L129	N:N:F118	10.96	Yes	No	17	0	0
156	L:L:L129	N:N:V133	5.96	Yes	No	17	0	0
157	L:L:C132	N:N:P119	5.65	No	No	7	0	0
158	L:L:C132	N:N:F209	5.59	No	Yes	7	0	0
159	L:L:C132	N:N:C214	7.28	No	No	0	0	0
160	L:L:R134	L:L:S135	7.91	Yes	No	0	0	0
161	L:L:R134	L:L:S218	3.95	Yes	No	0	0	0
162	L:L:E138	L:L:S137	7.19	No	No	0	0	0
163	L:L:S139	L:L:S191	3.26	No	No	0	0	0
164	L:L:A142	N:N:F116	4.16	No	No	0	0	0
165	L:L:L143	L:L:Y199	3.52	No	Yes	0	0	0
166	L:L:L143	L:L:V216	5.96	No	No	0	0	0
167	L:L:C145	L:L:C201	7.28	No	No	0	0	0
168	L:L:L146	L:L:S184	4.5	No	No	0	0	0
169	L:L:V147	L:L:V203	3.21	No	No	0	0	0
170	L:L:D149	L:L:K148	9.68	No	Yes	0	0	0
171	L:L:K148	L:L:Q176	8.14	Yes	No	18	0	0
172	L:L:K148	L:L:S182	6.12	Yes	No	18	0	0
173	L:L:D149	L:L:L180	6.79	No	No	0	0	0
174	L:L:E153	L:L:Y150	10.1	Yes	Yes	9	0	0
175	L:L:V155	L:L:Y150	11.36	No	Yes	9	0	0
176	L:L:Y150	L:L:Y181	8.94	Yes	Yes	9	0	0
177	L:L:L183	L:L:Y150	5.86	No	Yes	0	0	0
178	L:L:H205	L:L:Y150	4.36	Yes	Yes	9	0	0
179	L:L:F151	L:L:P152	13	Yes	Yes	0	0	0
180	L:L:F151	L:L:Y181	4.13	Yes	Yes	0	0	0
181	L:L:P152	L:L:P207	7.79	Yes	No	0	0	0
182	L:L:E153	L:L:P154	4.72	Yes	No	0	0	0
183	L:L:A173	L:L:E153	4.53	No	Yes	0	0	0
184	L:L:E153	L:L:Y181	15.71	Yes	Yes	9	0	0
185	L:L:H205	L:L:V155	5.54	Yes	No	9	0	0
186	L:L:D204	L:L:T156	4.34	No	No	0	0	0
187	L:L:S185	L:L:V157	6.46	No	No	0	0	0
188	L:L:C201	L:L:V157	3.42	No	No	0	0	0
189	L:L:S158	L:L:S161	6.52	No	No	19	0	0
190	L:L:N202	L:L:S158	7.45	No	No	19	0	0
191	L:L:L164	L:L:W159	4.56	No	Yes	20	0	0
192	L:L:S185	L:L:W159	4.94	No	Yes	0	0	0
193	L:L:V187	L:L:W159	14.71	No	Yes	20	0	0
194	L:L:C201	L:L:W159	9.14	No	Yes	0	0	0
195	L:L:N160	L:L:T200	4.39	No	No	0	0	0
196	L:L:N202	L:L:S161	7.45	No	No	19	0	0
197	L:L:L164	L:L:V187	5.96	No	No	20	0	0
198	L:L:V168	L:L:V187	3.21	No	No	0	0	0
199	L:L:H169	N:N:N138	5.1	No	No	0	0	0
200	L:L:H169	N:N:S174	13.95	No	No	0	0	0
201	L:L:S185	L:L:T170	4.8	No	No	0	0	0
202	L:L:F171	L:L:V186	5.24	Yes	No	0	0	0
203	L:L:F171	N:N:S162	5.28	Yes	No	22	0	0
204	L:L:F171	N:N:T164	5.19	Yes	No	0	0	0
205	L:L:F171	N:N:S176	17.18	Yes	No	22	0	0
206	L:L:V174	N:N:Q160	8.6	No	No	0	0	0
207	L:L:V174	N:N:S162	3.23	No	No	0	0	0
208	L:L:L175	L:L:Y181	10.55	No	Yes	0	0	0
209	L:L:Q176	L:L:S182	4.33	No	No	18	0	0
210	L:L:Q176	N:N:Q160	3.84	No	No	0	0	0
211	L:L:V186	N:N:L135	8.94	No	No	0	0	0
212	L:L:T188	N:N:N137	4.39	No	Yes	0	0	0
213	L:L:V189	L:L:Y199	7.57	No	Yes	0	0	0
214	L:L:P190	L:L:S193	7.13	No	No	0	0	0
215	L:L:K197	L:L:Y199	5.97	No	Yes	0	0	0
216	L:L:R215	L:L:T198	3.88	No	No	0	0	0
217	L:L:D213	L:L:N202	6.73	No	No	0	0	0
218	L:L:D204	L:L:K206	13.83	No	No	0	0	0
219	L:L:D204	L:L:K211	6.91	No	No	0	0	0
220	L:L:H205	L:L:P207	10.68	Yes	No	0	0	0
221	L:L:H205	L:L:S208	9.76	Yes	No	0	0	0
222	L:L:K214	N:N:E123	4.05	No	Yes	0	0	0
223	L:L:E217	L:L:R215	10.47	No	No	0	0	0
224	L:L:K219	N:N:C214	6.47	No	No	0	0	0
225	N:N:D1	N:N:P95	11.27	No	No	0	0	0
226	N:N:I2	N:N:Q27	12.35	Yes	No	0	0	0
227	N:N:I2	N:N:Q90	9.61	Yes	Yes	0	0	0
228	N:N:I2	N:N:R93	6.26	Yes	No	0	0	0
229	N:N:C88	N:N:M4	3.24	Yes	No	0	0	0
230	N:N:M4	N:N:Q90	8.16	No	Yes	23	0	0
231	N:N:M4	N:N:T97	4.52	No	No	23	0	0
232	N:N:C88	N:N:Q6	4.58	Yes	Yes	0	0	0
233	N:N:G99	N:N:Q6	4.93	No	Yes	0	0	0
234	N:N:Q100	N:N:Q6	7.68	No	Yes	0	0	0
235	N:N:G101	N:N:Q6	4.93	No	Yes	0	0	0
236	N:N:Q6	N:N:T102	9.92	Yes	No	0	0	0
237	N:N:S7	N:N:T22	4.8	No	Yes	0	0	0
238	N:N:L11	N:N:P8	6.57	No	No	0	0	0
239	N:N:E105	N:N:S10	5.75	Yes	No	0	0	0
240	N:N:K107	N:N:S12	4.59	No	No	0	0	0
241	N:N:A13	N:N:D17	4.63	No	No	0	0	0
242	N:N:P80	N:N:V15	5.3	No	No	0	0	0
243	N:N:G16	N:N:N77	3.39	No	No	0	0	0
244	N:N:R18	N:N:T74	6.47	No	Yes	0	0	0
245	N:N:I75	N:N:V19	6.14	No	Yes	6	0	0
246	N:N:L78	N:N:V19	5.96	No	Yes	6	0	0
247	N:N:T20	N:N:T74	7.85	No	Yes	12	0	0
248	N:N:I21	N:N:W35	4.7	No	Yes	0	0	0
249	N:N:I21	N:N:Y86	3.63	No	Yes	0	0	0
250	N:N:I21	N:N:T102	9.12	No	No	0	0	0
251	N:N:E70	N:N:T22	4.23	No	Yes	0	0	0
252	N:N:C23	N:N:C88	7.28	No	Yes	0	0	0
253	N:N:E70	N:N:K24	4.05	No	No	0	0	0
254	N:N:A25	N:N:V29	3.39	No	Yes	0	0	0
255	N:N:A25	N:N:T69	3.36	No	No	0	0	0
256	N:N:G68	N:N:N28	3.39	No	No	0	0	0
257	N:N:Q90	N:N:V29	7.16	Yes	Yes	0	0	0
258	N:N:N92	N:N:V29	4.43	No	Yes	0	0	0
259	N:N:H32	N:N:Y91	8.71	Yes	Yes	1	0	0
260	N:N:H32	N:N:N92	11.48	Yes	No	0	0	0
261	N:N:H32	R:R:T162	10.95	Yes	Yes	1	0	5
262	N:N:H32	R:R:Q165	8.65	Yes	Yes	1	0	6
263	N:N:F71	N:N:V33	14.42	No	No	0	0	0
264	N:N:I48	N:N:W35	8.22	No	Yes	0	0	0
265	N:N:L73	N:N:W35	21.64	No	Yes	0	0	0
266	N:N:C88	N:N:W35	9.14	Yes	Yes	0	0	0
267	N:N:Q89	N:N:Y36	7.89	Yes	No	1	0	0
268	N:N:K39	N:N:Q37	5.42	Yes	Yes	24	0	0
269	N:N:L47	N:N:Q37	3.99	No	Yes	0	0	0
270	N:N:A84	N:N:Q37	4.55	No	Yes	24	0	0
271	N:N:Q37	N:N:Y86	11.27	Yes	Yes	0	0	0
272	N:N:P44	N:N:Q38	14.21	Yes	No	1	0	0
273	N:N:Q38	N:N:Y87	7.89	No	Yes	1	0	0
274	N:N:K39	N:N:K42	4.31	Yes	No	0	0	0
275	N:N:A84	N:N:K39	4.82	No	Yes	24	0	0
276	N:N:E165	N:N:P40	4.72	No	No	0	0	0
277	N:N:R46	N:N:Y55	29.84	Yes	Yes	1	0	0
278	N:N:R46	N:N:S56	3.95	Yes	No	0	0	0
279	N:N:F62	N:N:L47	10.96	Yes	No	0	0	0
280	N:N:Y49	N:N:Y53	12.91	Yes	Yes	0	0	0
281	N:N:Y49	N:N:Y55	19.86	Yes	Yes	1	0	0
282	N:N:Y49	R:R:P235	4.17	Yes	Yes	1	0	4
283	N:N:S50	N:N:Y53	7.63	No	Yes	0	0	0
284	N:N:S50	R:R:T162	4.8	No	Yes	0	0	5
285	N:N:S52	N:N:Y53	5.09	No	Yes	0	0	0
286	N:N:Y53	R:R:Q234	12.4	Yes	No	0	0	3
287	N:N:R54	N:N:V58	7.85	No	No	0	0	0
288	N:N:R54	N:N:S60	7.91	No	No	0	0	0
289	N:N:P59	N:N:V58	3.53	No	No	0	0	0
290	N:N:P59	N:N:R61	11.53	No	Yes	6	0	0
291	N:N:F62	N:N:P59	8.67	Yes	No	6	0	0
292	N:N:F62	N:N:R61	3.21	Yes	Yes	6	0	0
293	N:N:Q79	N:N:R61	11.68	Yes	Yes	6	0	0
294	N:N:E81	N:N:R61	5.82	Yes	Yes	6	0	0
295	N:N:D82	N:N:R61	11.91	Yes	Yes	6	0	0
296	N:N:F62	N:N:I75	3.77	Yes	No	6	0	0
297	N:N:D82	N:N:F62	8.36	Yes	Yes	6	0	0
298	N:N:F62	N:N:Y86	5.16	Yes	Yes	0	0	0
299	N:N:S63	N:N:T74	4.8	No	Yes	0	0	0
300	N:N:G66	N:N:S65	3.71	No	No	0	0	0
301	N:N:G68	N:N:S67	3.71	No	No	0	0	0
302	N:N:I75	N:N:L78	4.28	No	No	6	0	0
303	N:N:N77	N:N:Q79	5.28	No	Yes	0	0	0
304	N:N:E81	N:N:Q79	10.19	Yes	Yes	6	0	0
305	N:N:D82	N:N:Q79	7.83	Yes	Yes	6	0	0
306	N:N:E81	N:N:P80	4.72	Yes	No	0	0	0
307	N:N:D82	N:N:E81	3.9	Yes	Yes	6	0	0
308	N:N:F83	N:N:L104	8.53	No	No	0	0	0
309	N:N:F83	N:N:I106	11.3	No	No	0	0	0
310	N:N:T85	N:N:Y87	7.49	No	Yes	0	0	0
311	N:N:K103	N:N:T85	4.5	No	No	0	0	0
312	N:N:L104	N:N:Y86	7.03	No	Yes	0	0	0
313	N:N:G101	N:N:Y87	5.79	No	Yes	0	0	0
314	N:N:Q89	N:N:Y91	7.89	Yes	Yes	1	0	0
315	N:N:Q89	N:N:Y96	7.89	Yes	Yes	1	0	0
316	N:N:F98	N:N:Q89	10.54	No	Yes	0	0	0
317	N:N:Q90	N:N:T97	5.67	Yes	No	23	0	0
318	N:N:Y91	N:N:Y96	3.97	Yes	Yes	1	0	0
319	N:N:Y91	R:R:N160	6.98	Yes	Yes	1	0	1
320	N:N:Y94	N:N:Y96	11.91	Yes	Yes	1	0	0
321	N:N:Y94	R:R:M156	3.59	Yes	No	1	0	3
322	N:N:Y94	R:R:N160	8.14	Yes	Yes	1	0	1
323	N:N:Y96	R:R:N160	10.47	Yes	Yes	1	0	1
324	N:N:E105	N:N:K103	8.1	Yes	No	0	0	0
325	N:N:E165	N:N:K103	5.4	No	No	0	0	0
326	N:N:E105	N:N:Q166	3.82	Yes	Yes	4	0	0
327	N:N:E105	N:N:Y173	8.98	Yes	Yes	4	0	0
328	N:N:I106	N:N:Q166	8.23	No	Yes	4	0	0
329	N:N:I106	N:N:S171	10.84	No	No	4	0	0
330	N:N:R108	N:N:T109	3.88	Yes	No	0	0	0
331	N:N:R108	N:N:Y140	12.35	Yes	No	0	0	0
332	N:N:R108	N:N:T172	5.17	Yes	No	0	0	0
333	N:N:L136	N:N:P113	3.28	Yes	Yes	4	0	0
334	N:N:F139	N:N:P113	7.22	Yes	Yes	4	0	0
335	N:N:H198	N:N:P113	6.1	Yes	Yes	4	0	0
336	N:N:L201	N:N:P113	3.28	No	Yes	0	0	0
337	N:N:N137	N:N:S114	4.47	Yes	No	0	0	0
338	N:N:L136	N:N:V115	4.47	Yes	No	4	0	0
339	N:N:V115	N:N:V196	3.21	No	No	4	0	0
340	N:N:K207	N:N:V115	4.55	No	No	0	0	0
341	N:N:F116	N:N:N137	4.83	No	Yes	0	0	0
342	N:N:F209	N:N:I117	6.28	Yes	No	0	0	0
343	N:N:F118	N:N:V133	6.55	No	No	17	0	0
344	N:N:F118	N:N:L135	7.31	No	No	0	0	0
345	N:N:F209	N:N:P119	5.78	Yes	No	7	0	0
346	N:N:A130	N:N:P120	3.74	No	No	7	0	0
347	N:N:P120	N:N:V132	3.53	No	No	0	0	0
348	N:N:P120	N:N:Y186	9.74	No	Yes	7	0	0
349	N:N:E123	N:N:S121	4.31	Yes	No	0	0	0
350	N:N:D122	N:N:E123	9.09	No	Yes	0	0	0
351	N:N:Q124	N:N:T129	4.25	Yes	No	0	0	0
352	N:N:Q124	N:N:S131	7.22	Yes	Yes	0	0	0
353	N:N:L125	N:N:Y186	4.69	No	Yes	0	0	0
354	N:N:A130	N:N:Y186	5.34	No	Yes	7	0	0
355	N:N:S131	N:N:T180	4.8	Yes	No	0	0	0
356	N:N:V132	N:N:W148	4.9	No	Yes	0	0	0
357	N:N:C134	N:N:W148	3.92	No	Yes	10	0	0
358	N:N:C134	N:N:C194	7.28	No	No	10	0	0
359	N:N:L135	N:N:N137	10.98	No	Yes	0	0	0
360	N:N:L136	N:N:L175	4.15	Yes	No	0	0	0
361	N:N:L136	N:N:V196	4.47	Yes	No	4	0	0
362	N:N:D170	N:N:N138	6.73	No	No	21	0	0
363	N:N:N138	N:N:T172	11.7	No	No	21	0	0
364	N:N:A144	N:N:F139	4.16	No	Yes	4	0	0
365	N:N:F139	N:N:Y173	4.13	Yes	Yes	4	0	0
366	N:N:F139	N:N:H198	5.66	Yes	Yes	4	0	0
367	N:N:P141	N:N:Y140	4.17	Yes	No	0	0	0
368	N:N:Q166	N:N:Y140	5.64	Yes	No	0	0	0
369	N:N:H198	N:N:P141	6.1	Yes	Yes	0	0	0
370	N:N:P141	N:N:Q199	4.74	Yes	No	0	0	0
371	N:N:R142	N:N:V163	14.38	No	No	0	0	0
372	N:N:R142	N:N:Y173	9.26	No	Yes	0	0	0
373	N:N:A144	N:N:H198	4.39	No	Yes	4	0	0
374	N:N:K145	N:N:Q147	8.14	No	No	0	0	0
375	N:N:K145	N:N:T197	4.5	No	No	0	0	0
376	N:N:S177	N:N:V146	3.23	Yes	No	0	0	0
377	N:N:V146	N:N:V196	3.21	No	No	0	0	0
378	N:N:E195	N:N:Q147	12.74	No	No	0	0	0
379	N:N:S159	N:N:W148	3.71	No	Yes	10	0	0
380	N:N:S177	N:N:W148	8.65	Yes	Yes	10	0	0
381	N:N:L179	N:N:W148	12.53	No	Yes	0	0	0
382	N:N:C194	N:N:W148	10.45	No	Yes	10	0	0
383	N:N:K149	N:N:N152	5.6	No	No	0	0	0
384	N:N:E195	N:N:K149	5.4	No	No	0	0	0
385	N:N:Q155	N:N:V150	10.03	No	No	0	0	0
386	N:N:H189	N:N:V150	6.92	Yes	No	7	0	0
387	N:N:V150	N:N:Y192	8.83	No	Yes	7	0	0
388	N:N:D151	N:N:H189	15.13	No	Yes	0	0	0
389	N:N:D151	N:N:V191	5.84	No	No	0	0	0
390	N:N:N158	N:N:Q155	5.28	No	No	0	0	0
391	N:N:L179	N:N:N158	4.12	No	No	0	0	0
392	N:N:S159	N:N:S177	3.26	No	Yes	10	0	0
393	N:N:S162	N:N:S176	3.26	No	No	22	0	0
394	N:N:Q166	N:N:S171	5.78	Yes	No	4	0	0
395	N:N:Q166	N:N:Y173	14.65	Yes	Yes	4	0	0
396	N:N:D167	N:N:K169	8.3	No	No	0	0	0
397	N:N:D167	N:N:D170	5.32	No	No	0	0	0
398	N:N:K169	N:N:S168	6.12	No	No	0	0	0
399	N:N:D170	N:N:T172	14.45	No	No	21	0	0
400	N:N:L179	N:N:L181	4.15	No	No	0	0	0
401	N:N:D185	N:N:L181	13.57	No	No	0	0	0
402	N:N:Y186	N:N:Y192	10.92	Yes	Yes	7	0	0
403	N:N:E187	N:N:R211	3.49	No	No	0	0	0
404	N:N:H189	N:N:K188	6.55	Yes	No	0	0	0
405	N:N:H189	N:N:Y192	3.27	Yes	Yes	7	0	0
406	N:N:N210	N:N:V191	5.91	No	No	0	0	0
407	N:N:F209	N:N:Y192	6.19	Yes	Yes	7	0	0
408	N:N:A193	N:N:S208	3.42	No	No	0	0	0
409	N:N:P204	N:N:T197	6.99	No	No	0	0	0
410	S:S:G20	S:S:P21	4.06	No	No	0	4	4
411	S:S:P240	S:S:W22	18.92	No	No	0	8	9
412	S:S:I244	S:S:L26	4.28	No	Yes	0	8	5
413	S:S:L26	S:S:V247	4.47	Yes	No	0	5	9
414	S:S:E27	S:S:F78	5.83	No	Yes	0	9	9
415	S:S:E27	S:S:I81	4.1	No	No	0	9	9
416	S:S:L29	S:S:W251	3.42	No	Yes	0	4	6
417	S:S:F78	S:S:I31	3.77	Yes	No	0	9	5
418	S:S:L32	S:S:W251	5.69	No	Yes	0	5	6
419	S:S:F74	S:S:G33	9.03	Yes	No	13	9	9
420	S:S:G33	S:S:W251	4.22	No	Yes	13	9	6
421	S:S:F74	S:S:I34	3.77	Yes	No	0	9	4
422	S:S:L71	S:S:T37	5.9	No	No	0	5	6
423	S:S:I258	S:S:L40	7.14	Yes	No	0	6	8
424	S:S:L41	S:S:L67	4.15	No	No	0	5	8
425	S:S:F44	S:S:Q63	5.86	Yes	Yes	0	6	6
426	S:S:F44	S:S:L67	6.09	Yes	No	0	6	8
427	S:S:F44	S:S:L262	3.65	Yes	No	0	6	4
428	S:S:F46	S:S:L47	3.65	No	No	0	4	7
429	S:S:M48	S:S:W57	6.98	No	No	0	3	6
430	S:S:I51	S:S:W57	3.52	No	No	0	5	6
431	S:S:D53	S:S:S55	8.83	No	No	0	4	4
432	S:S:D53	S:S:Q56	3.92	No	No	0	4	5
433	S:S:S55	S:S:W199	4.94	No	Yes	0	4	5
434	S:S:Q56	S:S:W199	5.48	No	Yes	0	5	5
435	S:S:L265	S:S:Q56	3.99	No	No	0	5	5
436	S:S:W126	S:S:W57	11.25	No	No	0	5	6
437	S:S:N58	S:S:S123	4.47	No	No	0	6	5
438	S:S:Q63	S:S:V59	8.6	Yes	No	3	6	5
439	S:S:H110	S:S:V59	8.3	Yes	No	3	8	5
440	S:S:L265	S:S:L60	4.15	No	No	0	5	4
441	S:S:P61	S:S:W126	9.46	No	No	0	5	5
442	S:S:C106	S:S:T62	3.38	Yes	No	0	8	5
443	S:S:H110	S:S:Q63	4.95	Yes	Yes	3	8	6
444	S:S:Q63	S:S:Y257	7.89	Yes	Yes	3	6	8
445	S:S:C106	S:S:L65	4.76	Yes	No	0	8	3
446	S:S:F66	S:S:V70	3.93	Yes	No	0	6	8
447	S:S:C103	S:S:F66	6.98	No	Yes	3	9	6
448	S:S:C106	S:S:F66	6.98	Yes	Yes	0	8	6
449	S:S:F66	S:S:L107	8.53	Yes	No	3	6	9
450	S:S:F253	S:S:F66	5.36	Yes	Yes	3	8	6
451	S:S:F66	S:S:Y257	7.22	Yes	Yes	3	6	8
452	S:S:F66	S:S:I258	5.02	Yes	Yes	3	6	6
453	S:S:I258	S:S:L67	8.56	Yes	No	0	6	8
454	S:S:L102	S:S:S69	7.51	No	No	0	5	5
455	S:S:G72	S:S:L99	3.42	No	No	0	9	8
456	S:S:L73	S:S:L99	4.15	No	No	0	7	8
457	S:S:F100	S:S:L73	7.31	Yes	No	0	9	7
458	S:S:A250	S:S:F74	6.93	No	Yes	0	8	9
459	S:S:F74	S:S:W251	8.02	Yes	Yes	13	9	6
460	S:S:F74	S:S:L254	3.65	Yes	No	13	9	5
461	S:S:F80	S:S:L76	4.87	Yes	No	0	9	8
462	S:S:L76	S:S:L95	5.54	No	No	0	8	9
463	S:S:F80	S:S:R92	23.52	Yes	No	0	9	9
464	S:S:F170	S:S:F80	4.29	Yes	Yes	0	9	9
465	S:S:F80	S:S:V242	6.55	Yes	No	0	9	7
466	S:S:E83	S:S:I82	4.1	No	No	0	3	8
467	S:S:E83	S:S:N85	14.46	No	No	0	3	6
468	S:S:M152	S:S:Q86	4.08	No	No	25	5	4
469	S:S:M157	S:S:Q86	12.23	No	No	25	1	4
470	S:S:Q86	S:S:V159	8.6	No	No	0	4	2
471	S:S:A89	S:S:F158	5.55	No	Yes	0	8	3
472	S:S:M152	S:S:P90	5.03	No	No	0	5	6
473	S:S:F158	S:S:P90	5.78	Yes	No	0	3	6
474	S:S:D239	S:S:R92	9.53	No	No	0	9	9
475	S:S:Y147	S:S:Y93	8.94	Yes	Yes	8	8	8
476	S:S:F158	S:S:Y93	15.47	Yes	Yes	8	3	8
477	S:S:L166	S:S:Y93	4.69	No	Yes	8	4	8
478	S:S:F170	S:S:Y93	11.35	Yes	Yes	0	9	8
479	S:S:F94	S:S:V98	10.49	Yes	No	0	8	9
480	S:S:A144	S:S:F94	4.16	No	Yes	0	8	8
481	S:S:L95	S:S:L99	5.54	No	No	0	9	8
482	S:S:F100	S:S:F96	11.79	Yes	Yes	0	9	9
483	S:S:F170	S:S:F96	15	Yes	Yes	0	9	9
484	S:S:F96	S:S:L174	4.87	Yes	No	0	9	8
485	S:S:F96	S:S:L246	4.87	Yes	No	0	9	9
486	S:S:G97	S:S:Q140	4.93	No	Yes	0	9	9
487	S:S:F100	S:S:F104	7.5	Yes	Yes	3	9	9
488	S:S:F100	S:S:W217	9.02	Yes	Yes	3	9	9
489	S:S:F100	S:S:N249	7.25	Yes	Yes	3	9	9
490	S:S:F100	S:S:F253	4.29	Yes	Yes	3	9	8
491	S:S:L102	S:S:S137	6.01	No	No	0	5	5
492	S:S:C103	S:S:F253	6.98	No	Yes	3	9	8
493	S:S:F104	S:S:M181	14.93	Yes	No	3	9	7
494	S:S:F104	S:S:S213	5.28	Yes	No	3	9	9
495	S:S:F104	S:S:W217	4.01	Yes	Yes	3	9	9
496	S:S:F104	S:S:F253	6.43	Yes	Yes	3	9	8
497	S:S:C136	S:S:S105	3.44	No	No	0	6	8
498	S:S:S105	S:S:S137	3.26	No	No	0	8	5
499	S:S:L107	S:S:Y257	7.03	No	Yes	3	9	8
500	S:S:L108	S:S:L183	5.54	Yes	No	0	7	5
501	S:S:L108	S:S:T184	10.32	Yes	No	0	7	6
502	S:S:L108	S:S:V187	4.47	Yes	No	0	7	5
503	S:S:A109	S:S:I132	3.25	No	No	0	7	4
504	S:S:H110	S:S:L114	9	Yes	No	3	8	8
505	S:S:H110	S:S:H202	3.58	Yes	Yes	3	8	7
506	S:S:H110	S:S:I206	6.63	Yes	Yes	0	8	7
507	S:S:H110	S:S:Y257	8.71	Yes	Yes	3	8	8
508	S:S:E261	S:S:H110	3.69	Yes	Yes	3	8	8
509	S:S:A111	S:S:V187	3.39	No	No	0	5	5
510	S:S:A111	S:S:I206	3.25	No	Yes	0	5	7
511	S:S:N113	S:S:S123	4.47	No	No	0	6	5
512	S:S:F124	S:S:N113	6.04	Yes	No	26	6	6
513	S:S:I129	S:S:N113	8.5	No	No	26	5	6
514	S:S:H202	S:S:L114	6.43	Yes	No	3	7	8
515	S:S:C121	S:S:K116	3.23	No	No	0	5	5
516	S:S:F124	S:S:K116	13.65	Yes	No	0	6	5
517	S:S:L117	S:S:S123	4.5	No	No	0	8	5
518	S:S:L117	S:S:W199	6.83	No	Yes	0	8	5
519	S:S:V118	S:S:W199	3.68	No	Yes	0	5	5
520	S:S:F124	S:S:T128	7.78	Yes	No	0	6	4
521	S:S:F124	S:S:I129	5.02	Yes	No	26	6	5
522	S:S:S125	S:S:T127	4.8	No	No	0	6	4
523	S:S:S125	S:S:T128	4.8	No	No	0	6	4
524	S:S:T127	S:S:W126	10.92	No	No	0	4	5
525	S:S:I134	S:S:L130	4.28	No	No	0	4	4
526	S:S:G135	S:S:L138	5.13	No	No	0	4	5
527	S:S:I143	S:S:L139	4.28	No	No	0	9	9
528	S:S:L139	S:S:Y176	16.41	No	No	0	9	9
529	S:S:Q140	S:S:Y176	6.76	Yes	No	0	9	9
530	S:S:Q140	S:S:V177	5.73	Yes	No	0	9	9
531	R:R:E146	S:S:I143	6.83	No	No	0	8	9
532	R:R:I143	S:S:E146	8.2	No	No	0	9	8
533	R:R:E146	S:S:E146	24.1	No	No	0	8	8
534	S:S:I151	S:S:Y147	12.09	No	Yes	8	8	8
535	S:S:F158	S:S:Y147	6.19	Yes	Yes	8	3	8
536	S:S:D169	S:S:Y147	10.34	No	Yes	0	9	8
537	S:S:L173	S:S:Y147	8.21	No	Yes	0	8	8
538	R:R:L150	S:S:Y147	8.21	No	Yes	0	6	8
539	R:R:Y147	S:S:L150	7.03	Yes	No	0	8	6
540	R:R:L150	S:S:L150	5.54	No	No	0	6	6
541	S:S:F158	S:S:I151	11.3	Yes	No	8	3	8
542	R:R:R154	S:S:I151	3.76	Yes	No	8	8	8
543	S:S:M152	S:S:M157	7.22	No	No	25	5	1
544	S:S:R154	S:S:T153	6.47	No	No	0	8	6
545	R:R:Q165	S:S:R154	16.35	Yes	No	0	6	8
546	R:R:D169	S:S:R154	16.68	No	No	0	9	8
547	S:S:F158	S:S:L166	4.87	Yes	No	8	3	4
548	S:S:N160	S:S:V159	4.43	No	No	0	1	2
549	S:S:M161	S:S:Q165	4.08	No	No	8	3	6
550	S:S:L166	S:S:M161	9.9	No	No	8	4	3
551	R:R:R154	S:S:M161	3.72	Yes	No	8	8	3
552	S:S:Q165	S:S:T162	11.34	No	No	0	6	5
553	R:R:R154	S:S:Q165	11.68	Yes	No	8	8	6
554	S:S:L224	S:S:N167	13.73	No	No	27	8	8
555	S:S:D238	S:S:N167	12.12	Yes	No	27	8	8
556	R:R:R154	S:S:D169	15.48	Yes	No	0	8	9
557	S:S:F170	S:S:W220	5.01	Yes	Yes	0	9	9
558	S:S:L225	S:S:V171	11.92	No	No	0	5	8
559	S:S:L174	S:S:V177	4.47	No	No	3	8	9
560	S:S:L174	S:S:W217	7.97	No	Yes	3	8	9
561	S:S:L180	S:S:Y176	11.72	No	No	0	9	9
562	S:S:V177	S:S:W217	4.9	No	Yes	3	9	9
563	S:S:L178	S:S:W217	4.56	No	Yes	0	7	9
564	S:S:M181	S:S:W217	12.8	No	Yes	3	7	9
565	S:S:F185	S:S:F207	8.57	Yes	Yes	28	4	4
566	S:S:F185	S:S:V210	3.93	Yes	No	0	4	4
567	S:S:F185	S:S:I214	3.77	Yes	No	0	4	4
568	S:S:I206	S:S:S188	4.64	Yes	No	0	7	7
569	S:S:F207	S:S:S188	3.96	Yes	No	0	4	7
570	S:S:F207	S:S:K189	3.72	Yes	No	0	4	1
571	S:S:F192	S:S:R204	4.28	No	No	0	5	4
572	S:S:F192	S:S:F207	8.57	No	Yes	0	5	4
573	S:S:G194	S:S:P195	4.06	No	No	0	8	5
574	S:S:C196	S:S:W199	5.22	No	Yes	0	4	5
575	S:S:E197	S:S:K200	10.8	No	No	0	3	6
576	S:S:N198	S:S:W199	6.78	No	Yes	0	4	5
577	S:S:H202	S:S:Q201	3.71	Yes	No	3	7	4
578	S:S:I264	S:S:Q201	8.23	No	No	3	3	4
579	S:S:E261	S:S:H202	13.54	Yes	Yes	3	8	7
580	S:S:H202	S:S:I264	5.3	Yes	No	3	7	3
581	S:S:L205	S:S:P260	6.57	No	No	0	4	8
582	S:S:E261	S:S:L205	6.63	Yes	No	0	8	4
583	S:S:T209	S:S:Y257	3.75	No	Yes	0	8	8
584	S:S:F212	S:S:L256	7.31	No	No	0	3	3
585	S:S:N249	S:S:S213	8.94	Yes	No	3	9	9
586	S:S:F253	S:S:S213	5.28	Yes	No	3	8	9
587	S:S:I216	S:S:N249	4.25	No	Yes	0	9	9
588	S:S:W217	S:S:W220	10.31	Yes	Yes	0	9	9
589	S:S:N249	S:S:W217	6.78	Yes	Yes	3	9	9
590	S:S:I221	S:S:W220	8.22	No	Yes	0	8	9
591	S:S:L224	S:S:W220	4.56	No	Yes	0	8	9
592	S:S:A245	S:S:W220	6.48	No	Yes	0	9	9
593	S:S:D238	S:S:L224	5.43	Yes	No	27	8	8
594	S:S:N228	S:S:W237	4.52	No	No	0	8	8
595	S:S:D238	S:S:N228	5.39	Yes	No	0	8	8
596	S:S:F231	S:S:W237	5.01	No	No	0	1	8
597	S:S:Q236	S:S:R233	11.68	No	No	0	1	2
598	S:S:R233	S:S:W237	21.99	No	No	0	2	8
599	S:S:D238	S:S:P235	4.83	Yes	No	0	8	4
600	S:S:F253	S:S:N249	6.04	Yes	Yes	3	8	9
601	S:S:L254	S:S:W251	5.69	No	Yes	13	5	6
602	S:S:L255	S:S:W251	5.69	No	Yes	0	4	6
603	S:S:L256	S:S:V252	4.47	No	No	0	3	7
604	S:S:I258	S:S:Y257	3.63	Yes	Yes	3	6	8
605	S:S:E261	S:S:Y257	8.98	Yes	Yes	3	8	8
606	S:S:P260	S:S:V259	3.53	No	No	0	8	5
607	S:S:I264	S:S:R267	6.26	No	No	0	3	5
608	R:R:G20	R:R:P21	4.06	No	No	0	4	4
609	R:R:I25	R:R:P21	3.39	No	No	0	8	4
610	R:R:G23	R:R:W22	4.22	No	Yes	0	9	9
611	R:R:L26	R:R:W22	3.42	Yes	Yes	2	5	9
612	R:R:P240	R:R:W22	20.27	No	Yes	0	8	9
613	R:R:C243	R:R:W22	3.92	Yes	Yes	2	8	9
614	R:R:C243	R:R:L26	4.76	Yes	Yes	2	8	5
615	R:R:I244	R:R:L26	4.28	No	Yes	0	8	5
616	R:R:L26	R:R:V247	4.47	Yes	No	0	5	9
617	R:R:E27	R:R:I31	4.1	No	No	29	9	5
618	R:R:E27	R:R:F78	9.33	No	Yes	29	9	9
619	R:R:F78	R:R:I31	5.02	Yes	No	29	9	5
620	R:R:F74	R:R:G33	9.03	Yes	No	14	9	9
621	R:R:G33	R:R:W251	4.22	No	Yes	14	9	6
622	R:R:I34	R:R:L71	4.28	Yes	No	0	4	5
623	R:R:F78	R:R:I34	3.77	Yes	Yes	0	9	4
624	R:R:T37	R:R:V70	4.76	No	No	0	6	8
625	R:R:L71	R:R:T37	5.9	No	No	0	5	6
626	R:R:L254	R:R:T37	4.42	Yes	No	0	5	6
627	R:R:I258	R:R:L40	5.71	Yes	No	0	6	8
628	R:R:F44	R:R:Q63	9.37	Yes	Yes	2	6	6
629	R:R:F44	R:R:L67	4.87	Yes	No	2	6	8
630	R:R:F44	R:R:I258	3.77	Yes	Yes	2	6	6
631	R:R:F44	R:R:L262	3.65	Yes	No	0	6	4
632	R:R:F46	R:R:K50	11.17	No	No	0	4	6
633	R:R:I51	R:R:L47	7.14	Yes	No	0	5	7
634	R:R:L60	R:R:M48	4.24	No	No	0	4	3
635	R:R:L64	R:R:M48	4.24	No	No	0	5	3
636	R:R:I51	R:R:Q56	4.12	Yes	Yes	30	5	5
637	R:R:I51	R:R:W57	3.52	Yes	No	0	5	6
638	R:R:I51	R:R:L265	5.71	Yes	No	30	5	5
639	R:R:D53	R:R:Q56	14.36	No	Yes	0	4	5
640	R:R:L117	R:R:S55	4.5	Yes	No	11	8	4
641	R:R:S123	R:R:S55	3.26	No	No	11	5	4
642	R:R:S55	R:R:W199	6.18	No	Yes	11	4	5
643	R:R:L265	R:R:Q56	6.65	No	Yes	30	5	5
644	R:R:L60	R:R:W57	4.56	No	No	0	4	6
645	R:R:N58	R:R:W126	3.39	No	Yes	0	6	5
646	R:R:Q63	R:R:V59	7.16	Yes	No	2	6	5
647	R:R:H110	R:R:V59	13.84	Yes	No	2	8	5
648	R:R:P61	R:R:W126	9.46	No	Yes	0	5	5
649	R:R:C106	R:R:T62	3.38	Yes	No	0	8	5
650	R:R:I129	R:R:T62	6.08	No	No	0	5	5
651	R:R:H110	R:R:Q63	3.71	Yes	Yes	2	8	6
652	R:R:Q63	R:R:Y257	6.76	Yes	Yes	2	6	8
653	R:R:E261	R:R:Q63	8.92	Yes	Yes	2	8	6
654	R:R:L102	R:R:L65	4.15	No	No	0	5	3
655	R:R:C106	R:R:L65	4.76	Yes	No	0	8	3
656	R:R:F66	R:R:V70	3.93	Yes	No	0	6	8
657	R:R:C103	R:R:F66	5.59	No	Yes	2	9	6
658	R:R:C106	R:R:F66	5.59	Yes	Yes	0	8	6
659	R:R:F66	R:R:L107	7.31	Yes	No	2	6	9
660	R:R:F253	R:R:F66	9.65	Yes	Yes	2	8	6
661	R:R:F66	R:R:Y257	5.16	Yes	Yes	2	6	8
662	R:R:F66	R:R:I258	5.02	Yes	Yes	2	6	6
663	R:R:I258	R:R:L67	8.56	Yes	No	2	6	8
664	R:R:L102	R:R:S69	7.51	No	No	0	5	5
665	R:R:G72	R:R:L99	3.42	No	No	0	9	8
666	R:R:L73	R:R:L99	4.15	No	No	0	7	8
667	R:R:F100	R:R:L73	8.53	Yes	No	0	9	7
668	R:R:L246	R:R:L73	4.15	No	No	0	9	7
669	R:R:A250	R:R:F74	6.93	No	Yes	0	8	9
670	R:R:F74	R:R:W251	8.02	Yes	Yes	14	9	6
671	R:R:F74	R:R:L254	3.65	Yes	Yes	14	9	5
672	R:R:F80	R:R:L76	3.65	Yes	No	0	9	8
673	R:R:L76	R:R:L95	5.54	No	No	0	8	9
674	R:R:F80	R:R:R92	23.52	Yes	No	0	9	9
675	R:R:F80	R:R:F96	3.22	Yes	Yes	2	9	9
676	R:R:F170	R:R:F80	4.29	Yes	Yes	2	9	9
677	R:R:F80	R:R:V242	6.55	Yes	No	0	9	7
678	R:R:C243	R:R:I81	3.27	Yes	No	0	8	9
679	R:R:L84	R:R:R92	10.93	No	No	0	4	9
680	R:R:N85	R:R:T88	8.77	No	No	0	6	9
681	R:R:M157	R:R:Q86	5.44	No	Yes	0	1	4
682	R:R:Q86	R:R:V159	4.3	Yes	No	0	4	2
683	R:R:A89	R:R:F158	4.16	No	Yes	0	8	3
684	R:R:M152	R:R:P90	8.39	No	No	2	5	6
685	R:R:F158	R:R:P90	4.33	Yes	No	2	3	6
686	R:R:D239	R:R:R92	10.72	No	No	0	9	9
687	R:R:Y147	R:R:Y93	9.93	Yes	Yes	2	8	8
688	R:R:F158	R:R:Y93	7.22	Yes	Yes	2	3	8
689	R:R:L166	R:R:Y93	5.86	No	Yes	0	4	8
690	R:R:F170	R:R:Y93	12.38	Yes	Yes	2	9	8
691	R:R:F94	R:R:V98	3.93	Yes	No	0	8	9
692	R:R:A144	R:R:F94	4.16	No	Yes	0	8	8
693	R:R:F94	R:R:T145	3.89	Yes	No	0	8	6
694	R:R:L95	R:R:L99	4.15	No	No	0	9	8
695	R:R:F100	R:R:F96	11.79	Yes	Yes	2	9	9
696	R:R:F170	R:R:F96	12.86	Yes	Yes	2	9	9
697	R:R:F96	R:R:L174	6.09	Yes	No	0	9	8
698	R:R:F96	R:R:W220	4.01	Yes	Yes	2	9	9
699	R:R:F96	R:R:L246	6.09	Yes	No	0	9	9
700	R:R:G97	R:R:Q140	4.93	No	Yes	0	9	9
701	R:R:I141	R:R:V98	6.14	No	No	0	7	9
702	R:R:F100	R:R:W217	11.02	Yes	Yes	2	9	9
703	R:R:F100	R:R:N249	8.46	Yes	Yes	2	9	9
704	R:R:F100	R:R:F253	3.22	Yes	Yes	2	9	8
705	R:R:L102	R:R:S137	6.01	No	No	0	5	5
706	R:R:C103	R:R:F253	6.98	No	Yes	2	9	8
707	R:R:F104	R:R:M181	13.68	No	No	0	9	7
708	R:R:F104	R:R:S213	5.28	No	No	2	9	9
709	R:R:F104	R:R:F253	6.43	No	Yes	2	9	8
710	R:R:C136	R:R:S105	3.44	No	No	0	6	8
711	R:R:S105	R:R:S137	3.26	No	No	0	8	5
712	R:R:L180	R:R:S105	4.5	No	No	0	9	8
713	R:R:L107	R:R:Y257	8.21	No	Yes	2	9	8
714	R:R:L108	R:R:L183	4.15	Yes	No	0	7	5
715	R:R:L108	R:R:T184	10.32	Yes	No	0	7	6
716	R:R:L108	R:R:V187	4.47	Yes	No	0	7	5
717	R:R:A109	R:R:I132	3.25	No	No	0	7	4
718	R:R:H110	R:R:L114	9	Yes	No	2	8	8
719	R:R:H110	R:R:H202	3.58	Yes	Yes	2	8	7
720	R:R:H110	R:R:I206	7.95	Yes	Yes	2	8	7
721	R:R:H110	R:R:Y257	9.8	Yes	Yes	2	8	8
722	R:R:E261	R:R:H110	6.15	Yes	Yes	2	8	8
723	R:R:A111	R:R:V187	3.39	No	No	0	5	5
724	R:R:A111	R:R:I206	3.25	No	Yes	0	5	7
725	R:R:L117	R:R:N113	5.49	Yes	Yes	11	8	6
726	R:R:N113	R:R:S123	5.96	Yes	No	11	6	5
727	R:R:F124	R:R:N113	3.62	Yes	Yes	0	6	6
728	R:R:I129	R:R:N113	7.08	No	Yes	0	5	6
729	R:R:H202	R:R:L114	6.43	Yes	No	2	7	8
730	R:R:C121	R:R:K116	6.47	No	No	0	5	5
731	R:R:F124	R:R:K116	12.41	Yes	No	0	6	5
732	R:R:L117	R:R:S123	9.01	Yes	No	11	8	5
733	R:R:L117	R:R:W199	12.53	Yes	Yes	11	8	5
734	R:R:C193	R:R:R119	4.18	No	No	0	5	7
735	R:R:F124	R:R:T128	9.08	Yes	No	0	6	4
736	R:R:S125	R:R:T127	4.8	No	No	0	6	4
737	R:R:S125	R:R:T128	4.8	No	No	0	6	4
738	R:R:T127	R:R:W126	10.92	No	Yes	0	4	5
739	R:R:I134	R:R:L130	7.14	No	No	0	4	4
740	R:R:G135	R:R:L138	5.13	No	No	0	4	5
741	R:R:I143	R:R:L139	4.28	No	No	0	9	9
742	R:R:L139	R:R:Y176	21.1	No	No	0	9	9
743	R:R:Q140	R:R:Y176	5.64	Yes	No	0	9	9
744	R:R:Q140	R:R:V177	5.73	Yes	No	0	9	9
745	R:R:E146	R:R:L150	3.98	No	No	0	8	6
746	R:R:I151	R:R:Y147	12.09	No	Yes	2	8	8
747	R:R:F158	R:R:Y147	4.13	Yes	Yes	2	3	8
748	R:R:D169	R:R:Y147	10.34	No	Yes	0	9	8
749	R:R:L173	R:R:Y147	8.21	No	Yes	0	8	8
750	R:R:F158	R:R:I151	10.05	Yes	No	2	3	8
751	R:R:F158	R:R:M152	3.73	Yes	No	2	3	5
752	R:R:R154	R:R:T153	3.88	Yes	No	0	8	6
753	R:R:M156	R:R:N160	7.01	No	Yes	1	3	1
754	R:R:N160	R:R:V159	4.43	Yes	No	0	1	2
755	R:R:M161	R:R:Q165	4.08	No	Yes	0	3	6
756	R:R:L166	R:R:M161	8.48	No	No	0	4	3
757	R:R:P163	R:R:T162	3.5	No	Yes	1	6	5
758	R:R:Q165	R:R:T162	8.5	Yes	Yes	1	6	5
759	R:R:P163	R:R:P235	7.79	No	Yes	1	6	4
760	R:R:C164	R:R:Q234	4.58	No	No	0	1	3
761	R:R:L224	R:R:N167	13.73	No	No	1	8	8
762	R:R:D238	R:R:N167	10.77	Yes	No	1	8	8
763	R:R:F170	R:R:W220	4.01	Yes	Yes	2	9	9
764	R:R:L225	R:R:V171	11.92	No	No	0	5	8
765	R:R:L174	R:R:W217	9.11	No	Yes	0	8	9
766	R:R:L180	R:R:Y176	11.72	No	No	0	9	9
767	R:R:V177	R:R:W217	4.9	No	Yes	0	9	9
768	R:R:L178	R:R:W217	4.56	No	Yes	0	7	9
769	R:R:F179	R:R:L183	4.87	No	No	0	3	5
770	R:R:I214	R:R:M181	4.37	No	No	0	4	7
771	R:R:M181	R:R:W217	15.12	No	Yes	0	7	9
772	R:R:F185	R:R:F207	9.65	Yes	Yes	0	4	4
773	R:R:F185	R:R:V210	3.93	Yes	No	0	4	4
774	R:R:F185	R:R:I214	3.77	Yes	No	0	4	4
775	R:R:F186	R:R:K189	3.72	No	No	0	3	1
776	R:R:I206	R:R:S188	4.64	Yes	No	0	7	7
777	R:R:F207	R:R:S188	5.28	Yes	No	0	4	7
778	R:R:F207	R:R:K189	3.72	Yes	No	0	4	1
779	R:R:G203	R:R:T191	3.64	No	No	0	7	4
780	R:R:F192	R:R:F207	11.79	No	Yes	0	5	4
781	R:R:G194	R:R:P195	4.06	No	No	0	8	5
782	R:R:N198	R:R:W199	13.56	No	Yes	0	4	5
783	R:R:H202	R:R:Q201	3.71	Yes	No	2	7	4
784	R:R:I264	R:R:Q201	10.98	No	No	2	3	4
785	R:R:E261	R:R:H202	13.54	Yes	Yes	2	8	7
786	R:R:H202	R:R:I264	6.63	Yes	No	2	7	3
787	R:R:L205	R:R:P260	6.57	No	No	0	4	8
788	R:R:I206	R:R:Y257	3.63	Yes	Yes	2	7	8
789	R:R:I208	R:R:L256	4.28	No	No	0	3	3
790	R:R:T209	R:R:Y257	3.75	No	Yes	0	8	8
791	R:R:F212	R:R:L256	6.09	No	No	0	3	3
792	R:R:N249	R:R:S213	8.94	Yes	No	2	9	9
793	R:R:F253	R:R:S213	3.96	Yes	No	2	8	9
794	R:R:W217	R:R:W220	17.81	Yes	Yes	2	9	9
795	R:R:N249	R:R:W217	4.52	Yes	Yes	2	9	9
796	R:R:I221	R:R:W220	8.22	No	Yes	0	8	9
797	R:R:A245	R:R:W220	6.48	No	Yes	0	9	9
798	R:R:G227	R:R:M223	3.49	No	No	0	7	7
799	R:R:D238	R:R:L224	5.43	Yes	No	1	8	8
800	R:R:Q230	R:R:R226	10.51	No	No	0	1	4
801	R:R:N228	R:R:W237	6.78	Yes	No	0	8	8
802	R:R:D238	R:R:N228	6.73	Yes	Yes	0	8	8
803	R:R:P229	R:R:Q234	12.63	No	No	0	1	3
804	R:R:R233	R:R:W237	20.99	No	No	0	2	8
805	R:R:P235	R:R:Q236	4.74	Yes	No	0	4	1
806	R:R:D238	R:R:P235	3.22	Yes	Yes	1	8	4
807	R:R:F253	R:R:N249	12.08	Yes	Yes	2	8	9
808	R:R:L254	R:R:W251	4.56	Yes	Yes	14	5	6
809	R:R:L255	R:R:W251	5.69	No	Yes	0	4	6
810	R:R:L256	R:R:V252	4.47	No	No	0	3	7
811	R:R:I258	R:R:Y257	3.63	Yes	Yes	2	6	8
812	R:R:E261	R:R:Y257	5.61	Yes	Yes	2	8	8
813	R:R:P260	R:R:V259	3.53	No	No	0	8	5
814	R:R:I264	R:R:R267	8.77	No	No	0	3	5
815	L:L:S7	L:L:T112	3.2	No	No	0	0	0
816	N:N:S67	N:N:T31	3.2	No	No	0	0	0
817	N:N:S65	N:N:T72	3.2	No	Yes	0	0	0
818	N:N:S131	N:N:T178	3.2	Yes	No	0	0	0
819	N:N:S174	N:N:T164	3.2	No	No	0	0	0
820	N:N:S208	N:N:T206	3.2	No	No	0	0	0
821	L:L:T91	L:L:V116	3.17	No	No	0	0	0
822	S:S:C243	S:S:L26	3.17	No	Yes	0	8	5
823	S:S:T37	S:S:V70	3.17	No	No	0	6	8
824	S:S:T191	S:S:V115	3.17	No	No	0	4	6
825	S:S:H202	S:S:W199	3.17	Yes	Yes	0	7	5
826	S:S:P235	S:S:Q234	3.16	No	No	0	4	3
827	N:N:A112	N:N:L201	3.15	No	No	0	0	0
828	S:S:A250	S:S:L73	3.15	No	No	0	8	7
829	S:S:A89	S:S:L84	3.15	No	No	0	8	4
830	R:R:A43	R:R:L262	3.15	No	No	0	5	4
831	N:N:E143	N:N:P141	3.14	No	Yes	0	0	0
832	S:S:T149	S:S:T153	3.14	No	No	0	7	6
833	L:L:A163	L:L:N160	3.13	No	No	0	0	0
834	N:N:I2	N:N:S26	3.1	Yes	No	0	0	0
835	L:L:A100	L:L:D106	3.09	No	Yes	0	0	0
836	S:S:I141	S:S:V98	3.07	No	No	0	7	9
837	N:N:K190	N:N:V191	3.04	No	No	0	0	0
838	S:S:I216	S:S:T248	3.04	No	No	0	9	5
839	L:L:A40	L:L:Q43	3.03	No	No	0	0	0
840	S:S:A101	S:S:Q140	3.03	No	Yes	0	6	9
841	R:R:A101	R:R:Q140	3.03	No	Yes	0	6	9
842	S:S:F78	S:S:G75	3.01	Yes	No	0	9	5
843	L:L:L146	N:N:S131	3	No	Yes	0	0	0
844	L:L:K148	N:N:T180	3	Yes	No	0	0	0
845	L:L:L180	L:L:S178	3	No	No	0	0	0
846	S:S:L180	S:S:S105	3	No	No	0	9	8
847	S:S:L108	S:S:S112	3	Yes	No	0	7	4
848	R:R:L108	R:R:S112	3	Yes	No	0	7	4
849	L:L:L183	L:L:V147	2.98	No	No	0	0	0
850	N:N:L11	N:N:V19	2.98	No	Yes	0	0	0
851	N:N:L201	N:N:V205	2.98	No	No	0	0	0
852	S:S:L29	S:S:V247	2.98	No	No	0	4	9
853	S:S:L32	S:S:V36	2.98	No	No	0	5	4
854	S:S:L40	S:S:V36	2.98	No	No	0	8	4
855	S:S:L95	S:S:V91	2.98	No	No	0	9	7
856	S:S:L102	S:S:V98	2.98	No	No	0	5	9
857	R:R:L32	R:R:V36	2.98	No	No	0	5	4
858	R:R:L39	R:R:V35	2.98	No	No	0	4	5
859	R:R:L40	R:R:V36	2.98	No	No	0	8	4
860	R:R:L254	R:R:V36	2.98	Yes	No	0	5	4
861	R:R:L40	R:R:V259	2.98	No	No	0	8	5
862	L:L:N35	L:L:V99	2.96	Yes	No	0	0	0
863	S:S:N249	S:S:V252	2.96	Yes	No	0	9	7
864	R:R:N228	R:R:V241	2.96	Yes	No	0	8	8
865	S:S:L130	S:S:T62	2.95	No	No	0	4	5
866	S:S:I34	S:S:I38	2.94	No	No	0	4	3
867	R:R:I142	S:S:I143	2.94	No	No	0	7	9
868	N:N:A30	N:N:H32	2.93	No	Yes	0	0	0
869	R:R:D169	R:R:V168	2.92	No	No	0	9	2
870	L:L:G44	N:N:Y87	2.9	No	Yes	0	0	0
871	L:L:Q3	L:L:S25	2.89	No	No	0	0	0
872	N:N:Q124	N:N:S127	2.89	Yes	No	0	0	0
873	R:R:M156	S:S:M156	2.89	No	No	0	3	3
874	L:L:P131	L:L:R134	2.88	No	Yes	0	0	0
875	L:L:Q1	L:L:V2	2.87	No	Yes	0	0	0
876	L:L:Q110	L:L:V5	2.87	No	No	0	0	0
877	N:N:E105	N:N:S12	2.87	Yes	No	0	0	0
878	N:N:E161	N:N:S177	2.87	No	Yes	0	0	0
879	S:S:I134	S:S:L138	2.85	No	No	0	4	5
880	S:S:I215	S:S:L211	2.85	No	No	0	5	3
881	S:S:I221	S:S:L225	2.85	No	No	0	8	5
882	R:R:I215	R:R:L211	2.85	No	No	0	5	3
883	R:R:I221	R:R:L225	2.85	No	No	0	8	5
884	R:R:I216	R:R:N249	2.83	No	Yes	0	9	9
885	N:N:E195	N:N:T206	2.82	No	No	0	0	0
886	L:L:G144	L:L:W159	2.81	No	Yes	0	0	0
887	S:S:G20	S:S:W22	2.81	No	No	0	4	9
888	R:R:W126	R:R:W57	2.81	Yes	No	0	5	6
889	R:R:M223	R:R:N228	2.8	No	Yes	0	7	8
890	R:R:C243	R:R:F80	2.79	Yes	Yes	2	8	9
891	N:N:A51	N:N:F71	2.77	No	No	0	0	0
892	N:N:A111	N:N:R108	2.77	No	Yes	0	0	0
893	S:S:A30	S:S:F78	2.77	No	Yes	0	9	9
894	R:R:A30	R:R:F78	2.77	No	Yes	0	9	9
895	R:R:L41	R:R:L67	2.77	No	No	0	5	8
896	R:R:L45	R:R:L64	2.77	No	No	0	5	5
897	L:L:L164	L:L:N160	2.75	No	No	0	0	0
898	L:L:W47	N:N:P95	2.7	Yes	No	0	0	0
899	R:R:E197	R:R:K200	2.7	No	No	0	3	6
900	L:L:Y95	N:N:A43	2.67	Yes	No	0	0	0
901	N:N:L154	N:N:Q147	2.66	No	No	0	0	0
902	L:L:F127	L:L:S125	2.64	No	No	0	0	0
903	N:N:F71	N:N:V29	2.62	No	Yes	0	0	0
904	S:S:F94	S:S:V148	2.62	Yes	No	0	8	7
905	R:R:C196	R:R:W199	2.61	No	Yes	0	4	5
906	L:L:A79	L:L:W36	2.59	No	Yes	0	0	0
907	S:S:R92	S:S:T88	2.59	No	No	0	9	9
908	S:S:F94	S:S:T145	2.59	Yes	No	0	8	6
909	R:R:F192	R:R:T191	2.59	No	No	0	5	4
910	L:L:S21	L:L:Y80	2.54	No	Yes	0	0	0
911	S:S:F78	S:S:I34	2.51	Yes	No	0	9	4
912	S:S:F212	S:S:I208	2.51	No	No	0	3	3
913	R:R:F124	R:R:I132	2.51	Yes	No	0	6	4
914	S:S:F231	S:S:M223	2.49	No	No	0	1	7
915	S:S:K50	S:S:R49	2.48	No	No	0	6	6
916	S:S:F186	S:S:K189	2.48	No	No	0	3	1
917	S:S:F44	S:S:L64	2.44	Yes	No	0	6	5
918	S:S:F179	S:S:L183	2.44	No	No	0	3	5
919	R:R:F94	R:R:L95	2.44	Yes	No	0	8	9
920	R:R:F185	R:R:L211	2.44	Yes	No	0	4	3
921	L:L:L194	L:L:R134	2.43	No	Yes	0	0	0
922	L:L:K219	L:L:Y220	2.39	No	No	0	0	0
923	L:L:L194	L:L:Y199	2.34	No	Yes	0	0	0
924	L:L:N52	L:L:Y54	2.33	Yes	No	1	0	0
925	S:S:L26	S:S:W22	2.28	Yes	No	0	5	9
926	R:R:L29	R:R:W251	2.28	No	Yes	0	4	6
927	R:R:G155	S:S:G155	2.11	No	No	0	4	4
928	S:S:P163	S:S:P235	1.95	No	No	0	6	4
929	L:L:A40	L:L:P41	1.87	No	No	0	0	0
930	L:L:A130	L:L:P131	1.87	No	No	0	0	0
931	N:N:G66	N:N:S67	1.86	No	No	0	0	0
932	N:N:G128	N:N:S127	1.86	No	No	0	0	0
933	N:N:G157	N:N:S156	1.86	No	No	0	0	0
934	N:N:G34	N:N:V33	1.84	No	No	0	0	0
935	N:N:G200	N:N:V110	1.84	No	No	0	0	0
936	S:S:G194	S:S:V118	1.84	No	No	0	8	5
937	R:R:G194	R:R:V118	1.84	No	No	0	8	5
938	S:S:G203	S:S:T191	1.82	No	No	0	7	4
939	S:S:A77	S:S:C243	1.81	No	No	0	8	8
940	S:S:A133	S:S:C106	1.81	No	Yes	0	8	8
941	R:R:A77	R:R:C243	1.81	No	Yes	0	8	8
942	R:R:A133	R:R:C106	1.81	No	Yes	0	8	8
943	S:S:A109	S:S:A133	1.79	No	No	0	7	8
944	L:L:P190	L:L:S192	1.78	No	No	0	0	0
945	N:N:P204	N:N:S203	1.78	No	No	0	0	0
946	L:L:P190	L:L:V189	1.77	No	No	0	0	0
947	N:N:P141	N:N:V110	1.77	Yes	No	0	0	0
948	R:R:P90	R:R:V148	1.77	No	No	0	6	7
949	S:S:G203	S:S:I206	1.76	No	Yes	0	7	7
950	R:R:G75	R:R:I34	1.76	No	Yes	0	5	4
951	R:R:G135	R:R:I134	1.76	No	No	0	4	4
952	L:L:P172	N:N:T164	1.75	No	No	0	0	0
953	S:S:G227	S:S:M223	1.75	No	No	0	7	7
954	N:N:G41	N:N:K42	1.74	No	No	0	0	0
955	R:R:G194	R:R:K200	1.74	No	No	0	8	6
956	L:L:G179	L:L:L175	1.71	No	No	0	0	0
957	N:N:G64	N:N:L73	1.71	No	No	0	0	0
958	S:S:C263	S:S:V259	1.71	No	No	0	5	5
959	R:R:C263	R:R:V259	1.71	No	No	0	5	5
960	N:N:A13	N:N:V19	1.7	No	Yes	0	0	0
961	S:S:A79	S:S:V91	1.7	No	No	0	8	7
962	R:R:A79	R:R:V91	1.7	No	No	0	8	7
963	R:R:A190	R:R:V115	1.7	No	No	0	4	6
964	S:S:C164	S:S:T162	1.69	No	No	0	1	5
965	R:R:I24	R:R:P21	1.69	No	No	0	8	4
966	N:N:A51	N:N:T31	1.68	No	No	0	0	0
967	L:L:K206	L:L:P207	1.67	No	No	0	0	0
968	L:L:G26	L:L:Q1	1.64	No	No	0	0	0
969	L:L:G44	L:L:Q43	1.64	No	No	0	0	0
970	L:L:E217	L:L:G221	1.64	No	No	0	0	0
971	R:R:G227	R:R:Q230	1.64	No	No	0	7	1
972	L:L:S21	L:L:S7	1.63	No	No	0	0	0
973	L:L:S135	L:L:S191	1.63	No	No	0	0	0
974	S:S:N228	S:S:P229	1.63	No	No	0	8	1
975	S:S:S222	S:S:V218	1.62	No	No	0	4	7
976	R:R:S222	R:R:V218	1.62	No	No	0	4	7
977	L:L:S56	L:L:T72	1.6	No	Yes	0	0	0
978	L:L:S133	L:L:T136	1.6	No	No	0	0	0
979	S:S:V168	S:S:V172	1.6	No	No	0	2	7
980	R:R:V115	R:R:V187	1.6	No	No	0	6	5
981	R:R:V168	R:R:V172	1.6	No	No	0	2	7
982	R:R:T209	R:R:V252	1.59	No	No	0	8	7
983	L:L:A9	L:L:L113	1.58	No	No	0	0	0
984	L:L:A141	L:L:L194	1.58	No	No	0	0	0
985	S:S:A43	S:S:L262	1.58	No	No	0	5	4
986	R:R:A79	R:R:L76	1.58	No	No	0	8	8
987	L:L:T30	L:L:T74	1.57	No	No	0	0	0
988	L:L:T140	L:L:T188	1.57	No	No	0	0	0
989	N:N:T20	N:N:T22	1.57	No	Yes	12	0	0
990	N:N:T20	N:N:T72	1.57	No	Yes	12	0	0
991	N:N:T22	N:N:T72	1.57	Yes	Yes	12	0	0
992	N:N:T72	N:N:T74	1.57	Yes	Yes	12	0	0
993	R:R:T145	R:R:T149	1.57	No	No	0	6	7
994	R:R:T149	R:R:T153	1.57	No	No	0	7	6
995	S:S:I214	S:S:V218	1.54	No	No	0	4	7
996	N:N:A153	N:N:Q155	1.52	No	No	0	0	0
997	S:S:K200	S:S:V118	1.52	No	No	0	6	5
998	S:S:M223	S:S:V241	1.52	No	No	0	7	8
999	R:R:I216	R:R:T248	1.52	No	No	0	9	5
1000	R:R:I244	R:R:T248	1.52	No	No	0	8	5
1001	S:S:G227	S:S:R226	1.5	No	No	0	7	4
1002	N:N:N77	N:N:S76	1.49	No	No	0	0	0
1003	S:S:L39	S:S:V35	1.49	No	No	0	4	5
1004	N:N:D185	N:N:S182	1.47	No	No	0	0	0
1005	R:R:I34	R:R:I38	1.47	Yes	No	0	4	3
1006	R:R:L130	R:R:T62	1.47	No	No	0	4	5
1007	S:S:N85	S:S:T88	1.46	No	No	0	6	9
1008	L:L:G221	L:L:Y220	1.45	No	No	0	0	0
1009	L:L:S28	R:R:Q87	1.44	No	Yes	0	0	4
1010	N:N:Q3	N:N:S26	1.44	No	No	0	0	0
1011	N:N:Q100	N:N:S9	1.44	No	No	0	0	0
1012	N:N:K39	N:N:K45	1.44	Yes	No	0	0	0
1013	R:R:Q56	R:R:S268	1.44	Yes	No	0	5	4
1014	R:R:I25	R:R:L29	1.43	No	No	0	8	4
1015	N:N:Q100	N:N:T5	1.42	No	No	0	0	0
1016	S:S:Q87	S:S:T88	1.42	No	No	0	4	9
1017	N:N:K183	N:N:L125	1.41	No	No	0	0	0
1018	R:R:C121	R:R:R119	1.39	No	No	0	5	7
1019	S:S:L41	S:S:L68	1.38	No	No	0	5	4
1020	S:S:L45	S:S:L64	1.38	No	No	0	5	5
1021	S:S:L262	S:S:L47	1.38	No	No	0	4	7
1022	S:S:A190	S:S:R119	1.38	No	No	0	4	7
1023	R:R:L41	R:R:L68	1.38	No	No	0	5	4
1024	R:R:L42	R:R:L45	1.38	No	No	0	4	5
1025	N:N:E123	N:N:K126	1.35	Yes	No	0	0	0
1026	L:L:R84	L:L:S85	1.32	No	No	0	0	0
1027	N:N:E213	N:N:N210	1.31	No	No	0	0	0
1028	S:S:R119	S:S:V115	1.31	No	No	0	7	6
1029	R:R:M48	R:R:R49	1.24	No	No	0	3	6
1030	R:R:K200	R:R:R204	1.24	No	No	0	6	4
1031	R:R:F231	R:R:M223	1.24	No	No	0	1	7
1032	R:R:V118	R:R:W199	1.23	No	Yes	0	5	5
1033	S:S:F185	S:S:L211	1.22	Yes	No	28	4	3
1034	S:S:F207	S:S:L211	1.22	Yes	No	28	4	3
1035	L:L:Q65	L:L:Y60	1.13	No	Yes	0	0	0
1036	N:N:R211	N:N:Y186	1.03	No	Yes	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:V2	8.9775	4	1	0
2	L:L:Q6	4.69667	6	15	0
3	L:L:Y27	6.222	5	1	0
4	L:L:Y32	9.5675	4	1	0
5	L:L:N35	6.896	5	1	0
6	L:L:W36	6.4	6	15	0
7	L:L:R38	7.42	6	5	0
8	L:L:Q39	7.465	4	1	0
9	L:L:L45	8.56	4	1	0
10	L:L:W47	9.414	5	1	0
11	L:L:L50	5.186	5	1	0
12	L:L:N52	5.808	5	1	0
13	L:L:Y60	10.155	4	0	0
14	L:L:R67	7.73	4	5	0
15	L:L:M70	6.7125	4	0	0
16	L:L:T72	5.345	4	1	0
17	L:L:Y80	5.5775	4	0	0
18	L:L:L86	5.375	4	5	0
19	L:L:D90	7.042	5	5	0
20	L:L:Y94	5.858	5	5	0
21	L:L:Y95	5.45333	6	1	0
22	L:L:C96	6.115	4	15	0
23	L:L:R98	9.69667	6	1	0
24	L:L:R102	7.822	5	1	0
25	L:L:L105	6.405	4	1	0
26	L:L:D106	6.952	5	1	0
27	L:L:Y107	9.92	4	1	0
28	L:L:W108	7.44167	6	1	0
29	L:L:L129	6.55	4	17	0
30	L:L:R134	4.2925	4	0	0
31	L:L:K148	6.735	4	18	0
32	L:L:Y150	8.124	5	9	0
33	L:L:F151	6.99	4	0	0
34	L:L:P152	6.955	4	0	0
35	L:L:E153	8.765	4	9	0
36	L:L:W159	7.232	5	20	0
37	L:L:F171	8.2225	4	22	0
38	L:L:Y181	9.8325	4	9	0
39	L:L:Y199	4.85	4	0	0
40	L:L:H205	8.204	5	9	0
41	N:N:I2	7.83	4	0	0
42	N:N:Q6	6.408	5	0	0
43	N:N:V19	4.195	4	6	0
44	N:N:T22	3.0425	4	12	0
45	N:N:V29	4.4	4	0	0
46	N:N:H32	8.544	5	1	0
47	N:N:W35	10.925	4	0	0
48	N:N:Q37	6.3075	4	24	0
49	N:N:K39	3.9975	4	24	0
50	N:N:P44	8.455	4	1	0
51	N:N:R46	10.9675	4	1	0
52	N:N:Y49	12.39	4	1	0
53	N:N:Y53	9.5075	4	0	0
54	N:N:Y55	16.0975	4	1	0
55	N:N:R61	8.83	5	6	0
56	N:N:F62	6.68833	6	6	0
57	N:N:T72	1.9775	4	12	0
58	N:N:T74	5.1725	4	12	0
59	N:N:Q79	8.745	4	6	0
60	N:N:E81	6.1575	4	6	0
61	N:N:D82	8	4	6	0
62	N:N:Y86	6.7725	4	0	0
63	N:N:Y87	5.935	6	1	0
64	N:N:C88	6.06	4	0	0
65	N:N:Q89	8.5525	4	1	0
66	N:N:Q90	7.65	4	23	0
67	N:N:Y91	6.31	5	1	0
68	N:N:Y94	7.375	4	1	0
69	N:N:Y96	9.60333	6	1	0
70	N:N:E105	5.904	5	4	0
71	N:N:R108	6.0425	4	0	0
72	N:N:P113	4.97	4	4	0
73	N:N:E123	4.7	4	0	0
74	N:N:Q124	9.445	4	0	0
75	N:N:S131	4.555	4	0	0
76	N:N:L136	4.0925	4	4	0
77	N:N:N137	6.1675	4	0	0
78	N:N:F139	5.2925	4	4	0
79	N:N:P141	3.984	5	0	0
80	N:N:W148	7.36	6	10	0
81	N:N:Q166	7.624	5	4	0
82	N:N:Y173	9.255	4	4	0
83	N:N:S177	4.5025	4	10	0
84	N:N:Y186	6.344	5	7	0
85	N:N:H189	7.9675	4	7	0
86	N:N:Y192	7.3025	4	7	0
87	N:N:H198	5.5625	4	4	0
88	N:N:F209	5.96	4	7	0
89	S:S:L26	3.55	4	0	5
90	S:S:F44	4.51	4	0	6
91	S:S:Q63	6.825	4	3	6
92	S:S:F66	6.28857	7	3	6
93	S:S:F74	6.28	5	13	9
94	S:S:F78	3.578	5	0	9
95	S:S:F80	9.8075	4	0	9
96	S:S:Y93	10.1125	4	8	8
97	S:S:F94	4.965	4	0	8
98	S:S:F96	9.1325	4	0	9
99	S:S:F100	7.86	6	3	9
100	S:S:F104	7.63	5	3	9
101	S:S:C106	4.2325	4	0	8
102	S:S:L108	5.8325	4	0	7
103	S:S:H110	6.40857	7	3	8
104	S:S:F124	8.1225	4	26	6
105	S:S:Q140	5.1125	4	0	9
106	S:S:Y147	8.99667	6	8	8
107	S:S:F158	8.19333	6	8	3
108	S:S:F170	8.9125	4	0	9
109	S:S:F185	4.3725	4	28	4
110	S:S:W199	5.15714	7	0	5
111	S:S:H202	5.955	6	3	7
112	S:S:I206	4.07	4	0	7
113	S:S:F207	5.208	5	28	4
114	S:S:W217	7.54375	8	3	9
115	S:S:W220	6.916	5	0	9
116	S:S:D238	6.9425	4	27	8
117	S:S:N249	6.03667	6	3	9
118	S:S:W251	5.455	6	13	6
119	S:S:F253	5.73	6	3	8
120	S:S:Y257	6.74429	7	3	8
121	S:S:I258	6.0875	4	3	6
122	S:S:E261	8.21	4	3	8
123	R:R:W22	7.9575	4	2	9
124	R:R:L26	4.2325	4	2	5
125	R:R:I34	2.82	4	0	4
126	R:R:F44	5.415	4	2	6
127	R:R:I51	5.1225	4	30	5
128	R:R:Q56	6.6425	4	30	5
129	R:R:Q63	7.184	5	2	6
130	R:R:F66	6.03571	7	2	6
131	R:R:F74	6.9075	4	14	9
132	R:R:F78	5.2225	4	29	9
133	R:R:F80	7.33667	6	2	9
134	R:R:Q86	6.8225	4	1	4
135	R:R:Q87	4.775	4	1	4
136	R:R:Y93	8.8475	4	2	8
137	R:R:F94	3.605	4	0	8
138	R:R:F96	7.34333	6	2	9
139	R:R:F100	8.604	5	2	9
140	R:R:C106	3.885	4	0	8
141	R:R:L108	5.485	4	0	7
142	R:R:H110	7.71857	7	2	8
143	R:R:N113	5.5375	4	11	6
144	R:R:L117	7.8825	4	11	8
145	R:R:F124	6.905	4	0	6
146	R:R:W126	6.645	4	0	5
147	R:R:Q140	4.8325	4	0	9
148	R:R:Y147	8.62167	6	2	8
149	R:R:R154	7.704	5	8	8
150	R:R:F158	5.60333	6	2	3
151	R:R:N160	7.406	5	1	1
152	R:R:T162	6.9375	4	1	5
153	R:R:Q165	9.395	4	1	6
154	R:R:F170	8.385	4	2	9
155	R:R:F185	4.9475	4	0	4
156	R:R:W199	7.222	5	11	5
157	R:R:H202	6.778	5	2	7
158	R:R:I206	4.8675	4	2	7
159	R:R:F207	7.61	4	0	4
160	R:R:W217	9.57714	7	2	9
161	R:R:W220	8.106	5	2	9
162	R:R:N228	4.8175	4	0	8
163	R:R:P235	5.136	5	1	4
164	R:R:D238	6.66	5	1	8
165	R:R:C243	3.31	5	2	8
166	R:R:N249	7.366	5	2	9
167	R:R:W251	4.954	5	14	6
168	R:R:F253	7.05333	6	2	8
169	R:R:L254	3.9025	4	14	5
170	R:R:Y257	5.81875	8	2	8
171	R:R:I258	5.338	5	2	6
172	R:R:E261	8.555	4	2	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:C96	L:L:M34	34.23	3.24	Yes	No	0	0	0
2	L:L:M34	L:L:R98	34.4931	3.72	No	Yes	0	0	0
3	L:L:C96	L:L:W36	28.2943	7.84	Yes	Yes	15	0	0
4	L:L:G111	L:L:Q6	23.8744	3.29	No	Yes	0	0	0
5	L:L:Q6	L:L:T112	10.9002	7.09	Yes	No	0	0	0
6	L:L:S7	L:L:T112	13.7508	3.2	No	No	0	0	0
7	L:L:V114	L:L:V18	40.7723	4.81	No	No	0	0	0
8	L:L:V114	L:L:Y94	41.1656	6.31	No	Yes	0	0	0
9	L:L:M81	L:L:Y94	88.1716	3.59	No	Yes	0	0	0
10	L:L:M81	L:L:W36	88.5218	13.96	No	Yes	0	0	0
11	L:L:T115	L:L:T91	74.618	4.71	No	No	0	0	0
12	L:L:T91	L:L:V116	75.4446	3.17	No	No	0	0	0
13	L:L:L86	L:L:V116	78.7442	7.45	Yes	No	0	0	0
14	L:L:L86	L:L:V18	39.6043	4.47	Yes	No	0	0	0
15	L:L:D90	L:L:L86	39.8614	5.43	Yes	Yes	5	0	0
16	L:L:D90	L:L:R38	42.214	7.15	Yes	Yes	5	0	0
17	L:L:R38	L:L:Y94	44.5547	9.26	Yes	Yes	5	0	0
18	L:L:T115	L:L:V11	72.1338	4.76	No	No	0	0	0
19	L:L:P152	L:L:V11	71.3043	3.53	Yes	No	0	0	0
20	L:L:S21	L:L:Y80	11.1862	2.54	No	Yes	0	0	0
21	L:L:S21	L:L:S7	12.0418	1.63	No	No	0	0	0
22	L:L:M70	L:L:W36	49.984	5.82	Yes	Yes	0	0	0
23	L:L:G49	L:L:W47	49.1961	9.85	No	Yes	0	0	0
24	L:L:G49	L:L:M70	48.9841	3.49	No	Yes	0	0	0
25	L:L:G111	L:L:Y95	24.0542	5.79	No	Yes	0	0	0
26	L:L:W47	N:N:Y96	50.3296	16.4	Yes	Yes	1	0	0
27	L:L:Q39	L:L:Y95	21.3687	4.51	Yes	Yes	1	0	0
28	L:L:L45	N:N:F98	39.5059	14.61	Yes	No	0	0	0
29	L:L:Q39	N:N:Y87	21.0576	4.51	Yes	Yes	1	0	0
30	L:L:D106	L:L:R98	37.5299	11.91	Yes	Yes	1	0	0
31	L:L:R102	R:R:L84	23.7714	9.72	Yes	No	0	0	4
32	L:L:R102	R:R:P235	36.0667	5.76	Yes	Yes	1	0	4
33	N:N:Y49	R:R:P235	41.5214	4.17	Yes	Yes	1	0	4
34	N:N:Y49	N:N:Y55	44.3455	19.86	Yes	Yes	1	0	0
35	L:L:D106	N:N:Y55	40.4599	4.6	Yes	Yes	1	0	0
36	L:L:R102	R:R:D239	23.5566	10.72	Yes	No	0	0	9
37	N:N:H32	N:N:Y91	96.3432	8.71	Yes	Yes	1	0	0
38	N:N:H32	R:R:T162	11.1721	10.95	Yes	Yes	1	0	5
39	R:R:P163	R:R:T162	16.3901	3.5	No	Yes	1	6	5
40	N:N:Y91	N:N:Y96	50.9203	3.97	Yes	Yes	1	0	0
41	L:L:F151	L:L:P152	33.5487	13	Yes	Yes	0	0	0
42	L:L:F171	N:N:T164	21.1934	5.19	Yes	No	0	0	0
43	N:N:S174	N:N:T164	22.0412	3.2	No	No	0	0	0
44	L:L:H169	N:N:S174	22.4641	13.95	No	No	0	0	0
45	L:L:H169	N:N:N138	22.8862	5.1	No	No	0	0	0
46	N:N:N138	N:N:T172	23.2329	11.7	No	No	21	0	0
47	N:N:R108	N:N:T172	25.4042	5.17	Yes	No	0	0	0
48	N:N:R108	N:N:Y140	26.6537	12.35	Yes	No	0	0	0
49	N:N:Q166	N:N:Y140	27.7075	5.64	Yes	No	0	0	0
50	N:N:E105	N:N:Q166	27.0893	3.82	Yes	Yes	4	0	0
51	N:N:E105	N:N:K103	52.9534	8.1	Yes	No	0	0	0
52	N:N:K103	N:N:T85	53.9158	4.5	No	No	0	0	0
53	N:N:T85	N:N:Y87	54.2614	7.49	No	Yes	0	0	0
54	L:L:H205	L:L:P207	31.8943	10.68	Yes	No	0	0	0
55	L:L:P152	L:L:P207	36.1281	7.79	Yes	No	0	0	0
56	L:L:V126	L:L:V203	44.9384	6.41	No	No	0	0	0
57	L:L:V147	L:L:V203	46.6573	3.21	No	No	0	0	0
58	L:L:L183	L:L:V147	48.3755	2.98	No	No	0	0	0
59	L:L:L183	L:L:Y150	50.0929	5.86	No	Yes	0	0	0
60	L:L:Y150	L:L:Y181	25.8772	8.94	Yes	Yes	9	0	0
61	L:L:F151	L:L:Y181	31.0032	4.13	Yes	Yes	0	0	0
62	L:L:H205	L:L:Y150	25.9396	4.36	Yes	Yes	9	0	0
63	L:L:K214	L:L:V126	41.4985	4.55	No	No	0	0	0
64	L:L:L129	N:N:F118	11.1668	10.96	Yes	No	17	0	0
65	N:N:F118	N:N:L135	12.0474	7.31	No	No	0	0	0
66	L:L:V186	N:N:L135	15.074	8.94	No	No	0	0	0
67	L:L:F171	L:L:V186	15.5074	5.24	Yes	No	0	0	0
68	L:L:K214	L:L:P128	32.8786	3.35	No	No	0	0	0
69	L:L:P128	L:L:V216	29.4486	5.3	No	No	0	0	0
70	N:N:P120	N:N:Y186	10.4103	9.74	No	Yes	7	0	0
71	N:N:P120	N:N:V132	11.2705	3.53	No	No	0	0	0
72	N:N:V132	N:N:W148	11.6961	4.9	No	Yes	0	0	0
73	N:N:S177	N:N:W148	19.4086	8.65	Yes	Yes	10	0	0
74	N:N:S177	N:N:V146	20.6687	3.23	Yes	No	0	0	0
75	N:N:V146	N:N:V196	21.082	3.21	No	No	0	0	0
76	N:N:L136	N:N:V196	21.4593	4.47	Yes	No	4	0	0
77	N:N:L136	N:N:P113	23.138	3.28	Yes	Yes	4	0	0
78	N:N:F139	N:N:P113	23.3588	7.22	Yes	Yes	4	0	0
79	N:N:F139	N:N:Y173	24.5511	4.13	Yes	Yes	4	0	0
80	N:N:E105	N:N:Y173	24.5787	8.98	Yes	Yes	4	0	0
81	L:L:L194	L:L:R134	12.1504	2.43	No	Yes	0	0	0
82	L:L:L194	L:L:Y199	15.6157	2.34	No	Yes	0	0	0
83	L:L:L143	L:L:Y199	25.9946	3.52	No	Yes	0	0	0
84	L:L:L143	L:L:V216	27.722	5.96	No	No	0	0	0
85	N:N:H32	N:N:N92	22.5734	11.48	Yes	No	0	0	0
86	N:N:N92	N:N:V29	22.1911	4.43	No	Yes	0	0	0
87	N:N:Q90	N:N:V29	16.4342	7.16	Yes	Yes	0	0	0
88	N:N:G101	N:N:Y87	10.106	5.79	No	Yes	0	0	0
89	N:N:C88	N:N:M4	14.7746	3.24	Yes	No	0	0	0
90	N:N:M4	N:N:Q90	14.6681	8.16	No	Yes	23	0	0
91	N:N:I21	N:N:Y86	16.1803	3.63	No	Yes	0	0	0
92	N:N:F62	N:N:Y86	12.8839	5.16	Yes	Yes	0	0	0
93	N:N:C88	N:N:W35	11.6686	9.14	Yes	Yes	0	0	0
94	R:R:Q165	R:R:T162	11.1682	8.5	Yes	Yes	1	6	5
95	R:R:Q165	S:S:R154	74.2755	16.35	Yes	No	0	6	8
96	R:R:D169	S:S:R154	74.0851	16.68	No	No	0	9	8
97	R:R:D169	R:R:Y147	73.8957	10.34	No	Yes	0	9	8
98	R:R:Y147	S:S:L150	92.8134	7.03	Yes	No	0	8	6
99	R:R:L150	S:S:L150	92.5969	5.54	No	No	0	6	6
100	R:R:L150	S:S:Y147	86.6647	8.21	No	Yes	0	6	8
101	S:S:Y147	S:S:Y93	80.6418	8.94	Yes	Yes	8	8	8
102	S:S:F170	S:S:Y93	82.9969	11.35	Yes	Yes	0	9	8
103	S:S:F170	S:S:F96	65.9473	15	Yes	Yes	0	9	9
104	S:S:F100	S:S:F96	64.5875	11.79	Yes	Yes	0	9	9
105	S:S:F100	S:S:L73	11.2952	7.31	Yes	No	0	9	7
106	S:S:F100	S:S:F253	53.9253	4.29	Yes	Yes	3	9	8
107	S:S:F253	S:S:F66	57.7285	5.36	Yes	Yes	3	8	6
108	S:S:F66	S:S:Y257	46.8823	7.22	Yes	Yes	3	6	8
109	S:S:H110	S:S:Y257	26.8823	8.71	Yes	Yes	3	8	8
110	S:S:H110	S:S:H202	14.9759	3.58	Yes	Yes	3	8	7
111	S:S:H202	S:S:W199	26.1216	3.17	Yes	Yes	0	7	5
112	S:S:L117	S:S:W199	14.0103	6.83	No	Yes	0	8	5
113	S:S:L117	S:S:S123	13.14	4.5	No	No	0	8	5
114	S:S:N113	S:S:S123	11.3971	4.47	No	No	0	6	5
115	S:S:E261	S:S:Y257	16.656	8.98	Yes	Yes	3	8	8
116	S:S:E261	S:S:H202	14.57	13.54	Yes	Yes	3	8	7
117	S:S:F170	S:S:W220	12.4978	5.01	Yes	Yes	0	9	9
118	S:S:H110	S:S:I206	11.5805	6.63	Yes	Yes	0	8	7
119	R:R:L84	R:R:R92	23.7404	10.93	No	No	0	4	9
120	R:R:F80	R:R:R92	47.053	23.52	Yes	No	0	9	9
121	R:R:D239	R:R:R92	23.5411	10.72	No	No	0	9	9
122	R:R:F80	R:R:F96	32.7788	3.22	Yes	Yes	2	9	9
123	R:R:F100	R:R:F96	66.9673	11.79	Yes	Yes	2	9	9
124	R:R:F100	R:R:F253	63.9922	3.22	Yes	Yes	2	9	8
125	R:R:F253	R:R:F66	63.1133	9.65	Yes	Yes	2	8	6
126	R:R:F66	R:R:V70	12.3701	3.93	Yes	No	0	6	8
127	R:R:T37	R:R:V70	11.8129	4.76	No	No	0	6	8
128	R:R:F66	R:R:Y257	17.3822	5.16	Yes	Yes	2	6	8
129	R:R:C106	R:R:F66	28.4372	5.59	Yes	Yes	0	8	6
130	R:R:C106	R:R:T62	25.9234	3.38	Yes	No	0	8	5
131	R:R:I129	R:R:T62	23.1779	6.08	No	No	0	5	5
132	R:R:I129	R:R:N113	22.6266	7.08	No	Yes	0	5	6
133	R:R:F124	R:R:N113	14.8356	3.62	Yes	Yes	0	6	6
134	R:R:F124	R:R:T128	10.8882	9.08	Yes	No	0	6	4
135	R:R:S125	R:R:T128	10.3215	4.8	No	No	0	6	4
136	R:R:M161	R:R:Q165	36.8384	4.08	No	Yes	0	3	6
137	R:R:L166	R:R:M161	36.7721	8.48	No	No	0	4	3
138	R:R:L166	R:R:Y93	36.7093	5.86	No	Yes	0	4	8
139	R:R:F170	R:R:Y93	56.5668	12.38	Yes	Yes	2	9	8
140	R:R:F170	R:R:W220	11.3668	4.01	Yes	Yes	2	9	9
141	R:R:W217	R:R:W220	11.3622	17.81	Yes	Yes	2	9	9
142	N:N:Q89	N:N:Y91	40.4429	7.89	Yes	Yes	1	0	0
143	L:L:Q6	L:L:W36	22.0871	3.29	Yes	Yes	15	0	0
144	N:N:H32	R:R:Q165	100	8.65	Yes	Yes	1	0	6
145	N:N:F98	N:N:Q89	39.7602	10.54	No	Yes	0	0	0
146	R:R:F170	R:R:F96	39.1652	12.86	Yes	Yes	2	9	9
147	L:L:L45	N:N:Y87	39.6279	7.03	Yes	Yes	1	0	0
148	N:N:I21	N:N:W35	10.4597	4.7	No	Yes	0	0	0
149	R:R:Y147	R:R:Y93	21.0735	9.93	Yes	Yes	2	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:T30	R:R:Q87	7.09	1	No	Yes	0	4	0	1
L:L:G31	R:R:Q87	4.93	0	No	Yes	0	4	0	1
L:L:Y32	R:R:E83	4.49	1	Yes	No	0	3	0	1
L:L:Y32	R:R:N85	9.3	1	Yes	No	0	6	0	1
L:L:T33	R:R:Q86	5.67	1	No	Yes	0	4	0	1
L:L:N52	R:R:Q86	11.88	1	Yes	Yes	0	4	0	1
L:L:Y54	R:R:Q87	5.64	1	No	Yes	0	4	0	1
L:L:L101	R:R:L84	6.92	0	No	No	0	4	0	1
L:L:R102	R:R:L84	9.72	1	Yes	No	0	4	0	1
L:L:R102	R:R:P163	5.76	1	Yes	No	0	6	0	1
L:L:R102	R:R:P235	5.76	1	Yes	Yes	0	4	0	1
L:L:R102	R:R:D238	7.15	1	Yes	Yes	0	8	0	1
L:L:R102	R:R:D239	10.72	1	Yes	No	0	9	0	1
N:N:H32	R:R:T162	10.95	1	Yes	Yes	0	5	0	1
N:N:H32	R:R:Q165	8.65	1	Yes	Yes	0	6	0	1
N:N:Y49	R:R:P235	4.17	1	Yes	Yes	0	4	0	1
N:N:S50	R:R:T162	4.8	0	No	Yes	0	5	0	1
N:N:Y53	R:R:Q234	12.4	0	Yes	No	0	3	0	1
N:N:Y91	R:R:N160	6.98	1	Yes	Yes	0	1	0	1
N:N:Y94	R:R:M156	3.59	1	Yes	No	0	3	0	1
N:N:Y94	R:R:N160	8.14	1	Yes	Yes	0	1	0	1
N:N:Y96	R:R:N160	10.47	1	Yes	Yes	0	1	0	1
R:R:Q165	S:S:R154	16.35	1	Yes	No	6	8	1	2
R:R:L84	R:R:R92	10.93	0	No	No	4	9	1	2
R:R:N85	R:R:T88	8.77	0	No	No	6	9	1	2
R:R:M157	R:R:Q86	5.44	0	No	Yes	1	4	2	1
R:R:Q86	R:R:V159	4.3	1	Yes	No	4	2	1	2
R:R:D239	R:R:R92	10.72	0	No	No	9	9	1	2
R:R:M156	R:R:N160	7.01	1	No	Yes	3	1	1	1
R:R:N160	R:R:V159	4.43	1	Yes	No	1	2	1	2
R:R:M161	R:R:Q165	4.08	0	No	Yes	3	6	2	1
R:R:P163	R:R:T162	3.5	1	No	Yes	6	5	1	1
R:R:Q165	R:R:T162	8.5	1	Yes	Yes	6	5	1	1
R:R:P163	R:R:P235	7.79	1	No	Yes	6	4	1	1
R:R:C164	R:R:Q234	4.58	0	No	No	1	3	2	1
R:R:L224	R:R:N167	13.73	1	No	No	8	8	2	2
R:R:D238	R:R:N167	10.77	1	Yes	No	8	8	1	2
R:R:D238	R:R:L224	5.43	1	Yes	No	8	8	1	2
R:R:D238	R:R:N228	6.73	1	Yes	Yes	8	8	1	2
R:R:P229	R:R:Q234	12.63	0	No	No	1	3	2	1
R:R:P235	R:R:Q236	4.74	1	Yes	No	4	1	1	2
R:R:D238	R:R:P235	3.22	1	Yes	Yes	8	4	1	1
R:R:M156	S:S:M156	2.89	1	No	No	3	3	1	2
L:L:S28	R:R:Q87	1.44	0	No	Yes	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
29.41	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
27.78	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
26.67	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
26.32	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
26.32	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
26.32	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
25.00	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
25.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
25.00	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
25.00	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
25.00	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
25.00	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
25.00	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
25.00	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
25.00	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
24.00	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
23.81	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
23.81	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
23.81	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
23.81	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
23.53	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
23.53	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
23.53	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
23.53	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
23.53	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
23.53	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
23.53	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
23.53	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
23.53	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
23.53	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
23.33	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
23.08	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
23.08	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
22.73	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
22.73	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
22.73	Single	8XQJ	JN241	8XQJ-Apelin-JN241
22.73	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
22.22	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
22.22	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
22.22	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
22.22	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
22.22	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
22.22	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
22.22	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
22.22	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
22.22	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
22.22	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
22.22	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
22.22	Single	8TH3	AT118-H Nanobody	8TH3-AT₁-AT118-H Nanobody
21.74	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
21.74	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
21.74	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
21.74	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
21.74	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
21.74	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
21.43	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
21.05	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
21.05	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
21.05	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
21.05	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
21.05	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
21.05	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
21.05	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
21.05	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
21.05	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
21.05	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
21.05	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
21.05	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
20.83	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
20.83	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
20.83	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
20.83	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
20.83	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
20.83	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
20.83	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
20.83	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
20.83	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.83	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
20.69	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
20.69	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
20.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
20.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
20.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
20.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
20.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
20.00	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
20.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
20.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
20.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
20.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
20.00	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
20.00	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
20.00	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
20.00	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
20.00	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
20.00	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
20.00	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
20.00	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
20.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
20.00	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
20.00	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
20.00	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
20.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
19.35	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
19.35	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
19.23	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
19.23	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
19.23	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
19.23	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
19.23	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
19.23	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
19.23	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
19.23	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
19.05	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
19.05	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
19.05	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
19.05	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
19.05	Single	6OS2	TRV026	6OS2-AT₁-TRV026
19.05	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
19.05	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
19.05	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
19.05	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
19.05	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/β1/γ2
19.05	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
19.05	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
19.05	Single	8XQJ	JN241	8XQJ-Apelin-JN241
19.05	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
19.05	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
19.05	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
19.05	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
19.05	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
19.05	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
19.05	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
19.05	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
19.05	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
19.05	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
19.05	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
18.75	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
18.75	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
18.75	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
18.75	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
18.52	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.52	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
18.52	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
18.52	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
18.52	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
18.18	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
18.18	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
18.18	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
18.18	Single	7EZC	UKA	7EZC-A_2A-UKA
18.18	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
18.18	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
18.18	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
18.18	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
18.18	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
18.18	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.18	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
17.86	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
17.86	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
17.86	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
17.86	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
17.86	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
17.86	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
17.86	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
17.65	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
17.65	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
17.65	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
17.65	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
17.65	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
17.65	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
17.65	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
17.65	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
17.65	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
17.65	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
17.65	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
17.65	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
17.65	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
17.65	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
17.65	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
17.39	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
17.39	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
17.39	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
17.39	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
17.39	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
17.39	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
17.39	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
17.39	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
17.39	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
17.24	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
17.24	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
17.24	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
17.24	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
17.24	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
16.67	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
16.67	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
16.67	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
16.67	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
16.67	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
16.67	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
16.67	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
16.67	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
16.67	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
16.67	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
16.67	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
16.67	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
16.67	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
16.67	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
16.67	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
16.67	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
16.67	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
16.67	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
16.67	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
16.67	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
16.67	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
16.67	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
16.67	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
16.67	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
16.67	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
16.67	Single	8YRG	Fospropofol	8YRG-MRGPRX4-Fospropofol-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
16.67	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
16.67	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
16.67	Consensus	a2_off	Orthosteric Ligand	a2a_off
16.67	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
16.67	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
16.67	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
16.67	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
16.67	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
16.67	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
16.67	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
16.67	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
16.13	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
16.13	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
16.13	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
16.13	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
16.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
16.00	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
16.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
16.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
16.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
16.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
16.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
16.00	Single	9E82	SDF-1-beta	9E82-ACKR3-SDF-1-β-Arrestin2
16.00	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
16.00	Single	9IQR	Muscarinic toxin 3	9IQR-α_2a-Muscarinic toxin 3
16.00	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
16.00	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
16.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
16.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
16.00	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
16.00	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
16.00	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
16.00	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
15.79	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
15.79	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
15.79	Single	5UEN	DU172	5UEN-A₁-DU172
15.79	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
15.79	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
15.79	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
15.79	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
15.79	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
15.79	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
15.79	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
15.79	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
15.79	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
15.79	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
15.79	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
15.79	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
15.79	Single	8ZYY	Neurotensin peptide 8-13	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
15.79	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
15.79	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
15.79	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
15.79	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
15.79	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
15.62	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
15.62	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
15.62	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
15.62	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
15.38	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
15.38	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
15.38	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
15.38	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
15.38	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
15.38	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
15.38	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
15.38	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
15.38	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
15.38	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
15.38	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
15.38	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
15.38	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
15.38	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
15.38	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
15.38	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
15.38	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
15.38	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
15.15	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
15.15	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
15.00	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
15.00	Single	5N2S	PSB36	5N2S-A₁-PSB36
15.00	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
15.00	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
15.00	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
15.00	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
15.00	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
15.00	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
15.00	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
15.00	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
15.00	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
15.00	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
15.00	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
15.00	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
15.00	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
15.00	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
15.00	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
14.81	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.81	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
14.81	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
14.81	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
14.81	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
14.81	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
14.81	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
14.81	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
14.81	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
14.81	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
14.81	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
14.81	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
14.81	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
14.81	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
14.29	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
14.29	Single	5V56	TC114	5V56-SMO-TC114
14.29	Single	5V57	TC114	5V57-SMO-TC114
14.29	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
14.29	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
14.29	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
14.29	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
14.29	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
14.29	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
14.29	Single	7V68	LY2119620	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
14.29	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
14.29	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
14.29	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
14.29	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
14.29	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
14.29	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
14.29	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
14.29	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
14.29	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
14.29	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
14.29	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
14.29	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
14.29	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
14.29	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
14.29	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
14.29	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
14.29	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
14.29	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
14.29	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
14.29	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
14.29	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
14.29	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
14.29	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
14.29	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
14.29	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
14.29	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
14.29	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
14.29	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
14.29	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
14.29	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
14.29	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
14.29	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
14.29	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	pac_on	Orthosteric Ligand	pac1_on
14.29	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
14.29	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
14.29	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
14.29	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
13.89	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
13.89	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
13.79	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
13.79	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
13.79	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
13.79	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
13.79	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
13.79	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
13.79	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
13.79	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
13.79	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
13.79	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
13.64	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
13.64	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
13.64	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
13.64	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
13.64	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
13.64	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
13.64	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
13.64	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
13.64	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
13.64	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
13.64	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
13.64	Single	8Y6W	TUG-1375	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
13.64	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
13.64	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
13.64	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
13.64	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
13.64	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
13.64	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
13.64	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
13.64	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
13.64	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
13.33	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
13.33	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
13.33	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
13.33	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
13.33	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
13.33	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
13.33	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
13.33	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
13.33	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
13.33	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
13.33	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
13.04	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
13.04	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
13.04	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
13.04	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
13.04	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
13.04	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
13.04	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
13.04	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
13.04	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
13.04	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
13.04	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
13.04	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
13.04	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
13.04	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
13.04	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
13.04	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
12.90	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
12.90	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
12.90	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
12.90	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
12.90	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
12.90	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
12.90	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
12.90	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
12.90	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
12.50	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
12.50	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
12.50	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
12.50	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
12.50	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
12.50	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
12.50	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
12.50	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
12.50	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
12.50	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
12.50	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
12.50	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
12.50	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
12.50	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
12.50	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
12.50	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
12.50	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
12.50	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
12.50	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
12.50	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
12.50	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
12.50	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
12.50	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
12.50	Single	9CM7	TUG-1375	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
12.50	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	9IZA	SCH900271	9IZA-HCA₂-SCH900271-Gi1/β1/γ2
12.50	Single	9JHJ	C18:0 Ceramide	9JHJ-FPR2-ALX-C18:0 Ceramide-Gi1/β1/γ2
12.50	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
12.50	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
12.50	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
12.12	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
12.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
12.00	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
12.00	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
12.00	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
12.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
12.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
12.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
12.00	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
12.00	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
12.00	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
12.00	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
12.00	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
12.00	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
12.00	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
12.00	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
12.00	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
12.00	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
12.00	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
12.00	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
12.00	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
12.00	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
12.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	6LI0	C17	6LI0-GPR52-C17
11.76	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
11.76	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
11.76	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
11.76	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
11.76	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
11.76	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
11.76	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
11.76	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
11.76	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
11.76	Single	8ZYU	Neurotensin peptide 8-13	8ZYU-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
11.76	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
11.76	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
11.76	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
11.76	Consensus	neurotensin_off	Orthosteric Ligand	nts1_off
11.76	Consensus	nts1_off	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
11.54	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
11.54	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
11.54	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
11.54	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
11.54	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
11.54	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.54	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
11.54	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
11.54	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
11.54	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
11.54	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
11.54	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
11.54	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
11.54	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
11.43	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
11.43	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
11.43	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
11.11	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
11.11	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
11.11	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
11.11	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
11.11	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
11.11	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
11.11	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
11.11	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
11.11	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
11.11	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
11.11	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
11.11	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
11.11	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
11.11	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
11.11	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
11.11	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
11.11	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
11.11	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
11.11	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
11.11	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
11.11	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
11.11	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
11.11	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
11.11	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
11.11	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
11.11	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
11.11	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
11.11	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
11.11	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
11.11	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
11.11	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
11.11	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
11.11	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
11.11	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
11.11	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
11.11	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
11.11	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
11.11	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
11.11	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
11.11	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
10.71	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
10.71	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
10.71	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
10.71	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
10.71	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
10.71	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
10.71	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
10.71	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
10.71	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
10.71	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
10.71	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
10.71	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
10.71	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
10.71	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
10.71	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
10.71	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
10.71	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
10.71	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
10.53	Single	3REY	XAC	3REY-A_2A-XAC
10.53	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
10.53	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
10.53	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
10.53	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
10.53	Single	7F61	PF-03654746	7F61-H₃-PF-03654746
10.53	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
10.53	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
10.53	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
10.53	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
10.53	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
10.53	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
10.53	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
10.53	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.53	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
10.53	Single	8Y6Y	GLPG0974	8Y6Y-FFA2-GLPG0974
10.53	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
10.53	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
10.53	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
10.53	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
10.53	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
10.53	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
10.53	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
10.53	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
10.34	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
10.34	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
10.34	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
10.34	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
10.34	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
10.34	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
10.34	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
10.34	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
10.34	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
10.34	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
10.34	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
10.34	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
10.34	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
10.34	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
10.34	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
10.00	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
10.00	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
10.00	Single	6D27	CAY10471	6D27-DP₂-CAY10471
10.00	Single	6FJ3	PTH	6FJ3-PTH1-PTH
10.00	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
10.00	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
10.00	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
10.00	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.00	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.00	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
10.00	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
10.00	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
10.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
10.00	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
10.00	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
10.00	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
10.00	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
10.00	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
10.00	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
10.00	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
10.00	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
10.00	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
10.00	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
10.00	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
10.00	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
10.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
10.00	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
10.00	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
10.00	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
10.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
10.00	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
10.00	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
10.00	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
10.00	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
10.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
10.00	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
10.00	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
10.00	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
10.00	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
10.00	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
10.00	Single	9KFJ	PubChem 138319674	9KFJ-RXFP3-PubChem 138319674-Gi2/β1/γ2
10.00	Consensus	a3_on	Orthosteric Ligand	a3a_on
10.00	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
10.00	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
10.00	Consensus	cck_off	Orthosteric Ligand	ccka_off
10.00	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
10.00	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
10.00	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
10.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
10.00	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
10.00	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
10.00	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
10.00	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
10.00	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
10.00	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
10.00	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
10.00	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
10.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
10.00	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
10.00	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
10.00	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
9.68	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
9.68	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
9.68	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.68	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
9.68	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
9.68	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
9.68	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
9.68	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
9.68	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.68	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
9.68	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
9.68	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
9.68	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
9.68	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
9.68	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
9.68	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
9.68	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
9.68	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
9.68	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
9.68	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
9.68	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.68	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.68	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
9.52	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
9.52	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
9.52	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
9.52	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
9.52	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
9.52	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
9.52	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
9.52	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
9.52	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
9.52	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
9.52	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
9.52	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
9.52	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
9.52	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
9.52	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
9.52	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
9.52	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
9.52	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
9.52	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
9.52	Single	8WGB	VU0155041	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
9.52	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.52	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
9.52	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
9.52	Single	9GE2	ML184	9GE2-GPR55-ML184-chim(NtGi1-G13)/β1/γ2
9.52	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
9.52	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
9.52	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
9.52	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
9.52	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
9.52	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
9.52	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
9.52	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
9.52	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
9.52	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
9.52	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
9.52	Consensus	dp_off	Orthosteric Ligand	dp2_off
9.52	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
9.52	Consensus	ep_off	Orthosteric Ligand	ep4_off
9.52	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
9.52	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
9.52	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
9.52	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
9.52	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
9.38	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
9.38	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
9.38	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
9.38	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
9.38	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
9.38	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
9.38	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
9.38	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
9.38	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
9.38	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
9.38	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
9.38	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
9.38	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
9.38	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
9.38	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
9.38	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.38	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
9.38	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
9.38	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
9.30	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
9.09	Single	3P0G	BI167107	3P0G-β₂-BI167107
9.09	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
9.09	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
9.09	Single	5TZR	MK8666	5TZR-FFA1-MK8666
9.09	Single	5XR8	AM841	5XR8-CB₁-AM841
9.09	Single	5XRA	AM11542	5XRA-CB₁-AM11542
9.09	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
9.09	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
9.09	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
9.09	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
9.09	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
9.09	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
9.09	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
9.09	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
9.09	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
9.09	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
9.09	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
9.09	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
9.09	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
9.09	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
9.09	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
9.09	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
9.09	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
9.09	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
9.09	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
9.09	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
9.09	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
9.09	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
9.09	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
9.09	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
9.09	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
9.09	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
9.09	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
9.09	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
9.09	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
9.09	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
9.09	Single	8ZWF	JR14a	8ZWF-C3a_B-JR14a
9.09	Single	9CLW	TUG-1375	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
9.09	Consensus	a2_on	Orthosteric Ligand	a2b_on
9.09	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
9.09	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
9.09	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
9.09	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
9.09	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
9.09	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
9.09	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
9.09	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
9.09	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
9.09	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
9.09	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
9.09	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
9.09	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
9.09	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
9.09	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
9.09	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
9.09	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
8.82	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
8.82	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
8.82	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
8.82	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
8.82	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
8.70	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
8.70	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
8.70	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
8.70	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
8.70	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
8.70	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
8.70	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
8.70	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
8.70	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
8.70	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
8.70	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
8.70	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
8.70	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
8.70	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
8.70	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
8.70	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
8.70	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.70	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.70	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
8.70	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
8.70	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
8.70	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
8.70	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
8.70	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
8.70	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
8.70	Single	8JWY	2-118	8JWY-A_2A-2-118
8.70	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
8.70	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
8.70	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
8.70	Single	9CM3	TUG-1375	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.70	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
8.70	Single	9M4Q	Doxazosin	9M4Q-Alpha1A-Doxazosin
8.70	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
8.70	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
8.70	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
8.70	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
8.70	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
8.70	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.70	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
8.70	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
8.70	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
8.70	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
8.70	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.70	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.70	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.57	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
8.57	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
8.57	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
8.57	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
8.57	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.57	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
8.57	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
8.33	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
8.33	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
8.33	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
8.33	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
8.33	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
8.33	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
8.33	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
8.33	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.33	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
8.33	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
8.33	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
8.33	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
8.33	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
8.33	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
8.33	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
8.33	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
8.33	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
8.33	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
8.33	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
8.33	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
8.33	Single	8W8S	AA-14	8W8S-GPR101-AA-14
8.33	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
8.33	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
8.33	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
8.33	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.33	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
8.33	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
8.33	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
8.33	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
8.33	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on adgrf_on adgrl_on adgre_on adgrd_on
8.33	Consensus	class-b2_on_gp	Orthosteric Ligand	adgrg_on_gp adgrf_on_gp adgrl_on_gp adgre_on_gp adgrd_on_gp
8.33	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
8.33	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
8.33	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
8.33	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
8.33	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
8.33	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
8.11	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
8.11	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
8.11	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
8.00	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
8.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
8.00	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
8.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
8.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
8.00	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
8.00	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
8.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
8.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
8.00	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
8.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
8.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
8.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
8.00	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
8.00	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
8.00	Single	9JF4	PD168368	9JF4-BB₁-PD168368
8.00	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
8.00	Single	9NS9	TUG-1375	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
8.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
8.00	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
8.00	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
8.00	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
8.00	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
8.00	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
7.89	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
7.69	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
7.69	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
7.69	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
7.69	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
7.69	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
7.69	Single	7QA8	Peptide	7QA8-STE2-Peptide
7.69	Single	7QA8	Peptide	7QA8-STE2-Peptide
7.69	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
7.69	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
7.69	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
7.69	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
7.69	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
7.69	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
7.69	Single	8W8R	AA-14	8W8R-GPR101-AA-14-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8WKY	PG-934	8WKY-MC₄-PG-934
7.69	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
7.69	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
7.69	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
7.69	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
7.69	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
7.69	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
7.69	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
7.69	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
7.69	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
7.69	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
7.69	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
7.69	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
7.69	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
7.69	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
7.69	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
7.69	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
7.50	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
7.41	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
7.41	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
7.41	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
7.41	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
7.41	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
7.41	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
7.41	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
7.41	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
7.41	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
7.41	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
7.32	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
7.32	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
7.14	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
7.14	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
7.14	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
7.14	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
7.14	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
7.14	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
7.14	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
7.14	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
7.14	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
6.90	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
6.90	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
6.90	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
6.90	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
6.90	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
6.90	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
6.90	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
6.90	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
6.90	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
6.90	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
6.90	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
6.90	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
6.90	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
6.67	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
6.67	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
6.67	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
6.67	Single	8HS2	Fab046	8HS2-GPR20-Fab046
6.67	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
6.67	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
6.45	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
6.45	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
6.45	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
6.45	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
6.45	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
6.25	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
6.25	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
6.25	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
6.25	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
6.25	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
6.25	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
6.25	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.25	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
6.25	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
6.25	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
6.25	Single	9EE9	Adenosine	9EE9-A_2A-Adenosine-Gs/β1/γ2
6.06	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
6.06	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
6.06	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.06	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
6.06	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
5.88	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
5.88	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
5.88	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
5.88	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
5.88	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
5.88	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
5.88	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
5.88	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
5.88	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
5.88	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
5.88	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
5.88	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
5.88	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
5.88	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
5.88	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
5.88	Single	8J6Q	Compound 9n	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
5.88	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
5.88	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
5.88	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
5.88	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
5.88	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
5.88	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
5.56	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
5.56	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
5.56	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
5.56	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
5.56	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
5.56	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
5.56	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
5.56	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
5.56	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
5.56	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
5.56	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
5.56	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
5.56	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
5.56	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.56	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/β1/γ2
5.56	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.56	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
5.56	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
5.56	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
5.56	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
5.56	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
5.56	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9B9Y	7DY	9B9Y-CB₁-7DY
5.56	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
5.56	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
5.56	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
5.56	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
5.56	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
5.56	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
5.56	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
5.56	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
5.56	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.26	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
5.26	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
5.26	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
5.26	Single	5U09	Taranabant	5U09-CB₁-Taranabant
5.26	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
5.26	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
5.26	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
5.26	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
5.26	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
5.26	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
5.26	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
5.26	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
5.26	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
5.26	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
5.26	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
5.26	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
5.26	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
5.26	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
5.26	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
5.26	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
5.26	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
5.26	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
5.26	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
5.26	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
5.26	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
5.26	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
5.26	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
5.26	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
5.26	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
5.26	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
5.26	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
5.26	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
5.26	Single	9H2X	A1IR1	9H2X-A_2A-A1IR1-Na
5.26	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
5.26	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
5.26	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
5.26	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.26	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
5.26	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
5.26	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
5.00	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
5.00	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
5.00	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
5.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
5.00	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
5.00	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
5.00	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
5.00	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
5.00	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
5.00	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
5.00	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
5.00	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
5.00	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
5.00	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.00	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.00	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
5.00	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
5.00	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
5.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
5.00	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
5.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.00	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
5.00	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
5.00	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.00	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
5.00	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
5.00	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
5.00	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
5.00	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
5.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
5.00	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
5.00	Single	8K9L	Damgo	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
5.00	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
5.00	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
5.00	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
5.00	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
5.00	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
5.00	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
5.00	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
5.00	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
5.00	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
5.00	Single	9IXX	LTD4	9IXX-CysLT₂-LTD4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
5.00	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
5.00	Single	9JMD	Azithromycin	9JMD-Motilin-Azithromycin-chim(Gs-CtGq)/β1/γ2
5.00	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Gi1/β1/γ2
5.00	Single	9KPD	SA0	9KPD-TAS2R16-SA0-chim(Gs-CtGt3)/β1/γ2
5.00	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
5.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
5.00	Consensus	hca_on	Orthosteric Ligand	hca2_on
5.00	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
5.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.00	Consensus	sensory_off	Orthosteric Ligand	opsins_off
4.76	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
4.76	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
4.76	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
4.76	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
4.76	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
4.76	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
4.76	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
4.76	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
4.76	Single	6GPS	MK0812	6GPS-CCR2-MK0812
4.76	Single	6IIV	Daltroban	6IIV-TXA2-Daltroban
4.76	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
4.76	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
4.76	Single	6PS1	Timolol	6PS1-β₂-Timolol
4.76	Single	7BU7	BI167107	7BU7-β₁-BI167107
4.76	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
4.76	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
4.76	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
4.76	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
4.76	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
4.76	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
4.76	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
4.76	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
4.76	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
4.76	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
4.76	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
4.76	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.76	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
4.76	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
4.76	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
4.76	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
4.76	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
4.76	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
4.76	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
4.76	Single	8JXR	LSD	8JXR-D₁-LSD
4.76	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
4.76	Single	8T1W	CVN424	8T1W-GPR6-CVN424
4.76	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
4.76	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
4.76	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
4.76	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
4.76	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
4.76	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
4.76	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
4.76	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
4.76	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
4.76	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
4.76	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
4.76	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
4.76	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
4.76	Consensus	blt_on	Orthosteric Ligand	blt1_on
4.76	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
4.76	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
4.76	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.76	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
4.76	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
4.76	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
4.76	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
4.76	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
4.76	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
4.55	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
4.55	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
4.55	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
4.55	Single	5C1M	BU72	5C1M-μ-BU72
4.55	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
4.55	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
4.55	Single	6E67	BI167107	6E67-β₂-BI167107-Gs(CT)
4.55	Single	6GPX	MK0812	6GPX-CCR2-MK0812
4.55	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
4.55	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
4.55	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
4.55	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
4.55	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
4.55	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.55	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.55	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
4.55	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
4.55	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
4.55	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
4.55	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
4.55	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
4.55	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
4.55	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
4.55	Single	7W41	PD176252	7W41-BB₂-PD176252
4.55	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
4.55	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
4.55	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
4.55	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
4.55	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
4.55	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
4.55	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
4.55	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.55	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
4.55	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
4.55	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
4.55	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
4.55	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
4.55	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.55	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
4.55	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.55	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.55	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
4.55	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
4.55	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
4.55	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
4.55	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
4.55	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
4.55	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
4.55	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go/β1/γ2
4.55	Single	9I52	A1IZU	9I52-D₁-A1IZU-Gs/β1/γ2
4.55	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
4.55	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
4.55	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
4.55	Consensus	blt_off	Orthosteric Ligand	blt1_off
4.55	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
4.55	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.55	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.55	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
4.55	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
4.55	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
4.55	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
4.35	Single	2YDV	NECA	2YDV-A_2A-NECA
4.35	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
4.35	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
4.35	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
4.35	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
4.35	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
4.35	Single	5G53	NECA	5G53-A_2A-NECA-Gs
4.35	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
4.35	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
4.35	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
4.35	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
4.35	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
4.35	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
4.35	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
4.35	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
4.35	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.35	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
4.35	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
4.35	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
4.35	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
4.35	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
4.35	Single	8E0G	BU72	8E0G-μ-BU72
4.35	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
4.35	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.35	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
4.35	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
4.35	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
4.35	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
4.35	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
4.35	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
4.35	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
4.35	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
4.35	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
4.35	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
4.35	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
4.35	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
4.35	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
4.35	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
4.35	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
4.35	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
4.35	Single	9EGO	YVF	9EGO-CB₁-YVF-Gi1/β1/γ2
4.35	Single	9I54	A1IZV	9I54-D₁-A1IZV-Gs/β1/γ2
4.35	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
4.35	Single	9UY3	Anamorelin	9UY3-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
4.35	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.35	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.35	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
4.35	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
4.35	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
4.35	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
4.35	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.35	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
4.35	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
4.35	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.35	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
4.17	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
4.17	Single	4LDE	BI167107	4LDE-β₂-BI167107
4.17	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
4.17	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
4.17	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
4.17	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
4.17	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
4.17	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
4.17	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
4.17	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
4.17	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
4.17	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
4.17	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
4.17	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.17	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.17	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
4.17	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.17	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
4.17	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
4.17	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
4.17	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
4.17	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
4.17	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
4.17	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
4.17	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.17	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
4.17	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.17	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
4.17	Single	9DGI	Z8526711350	9DGI-CB₁-Z8526711350
4.17	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
4.17	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
4.17	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.17	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.17	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
4.17	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
4.17	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
4.17	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.17	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
4.17	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
4.17	Consensus	orexin_on	Orthosteric Ligand	ox2_on
4.17	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.17	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.00	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
4.00	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
4.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
4.00	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
4.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
4.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
4.00	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
4.00	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
4.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
4.00	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
4.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
4.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
4.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
4.00	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
4.00	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
4.00	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
4.00	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
4.00	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
4.00	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
4.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
4.00	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
4.00	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
4.00	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
4.00	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
4.00	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
4.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
4.00	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.00	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.00	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
4.00	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
4.00	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.00	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
4.00	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
4.00	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
4.00	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
3.85	Single	6PT3	DPI-287	6PT3-δ-DPI-287
3.85	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
3.85	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
3.85	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
3.85	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
3.85	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
3.85	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
3.85	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
3.85	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
3.70	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
3.70	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
3.70	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
3.70	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
3.70	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
3.70	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
3.70	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
3.70	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
3.70	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
3.70	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
3.70	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
3.70	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
3.57	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
3.57	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
3.57	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
3.57	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
3.57	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
3.45	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
3.45	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.45	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
3.45	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
3.33	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
3.33	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
3.33	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
3.33	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.33	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.23	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
3.23	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.03	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
2.94	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
2.78	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1

PDB Summary
PDB	9IMA
Class	C
SubFamily	Orphan
Type	Orphan
SubType	GPRC5D
Species	Homo sapiens
Ligand	Talquetamab
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	2.65
Date	2024-09-11
D.O.I.	doi.org/10.1016/j.jmb.2024.168748

Net Summary
I_min	3.21
Number of Linked Nodes	882
Number of Links	1036
Number of Hubs	172
Number of Links mediated by Hubs	625
Number of Communities	30
Number of Nodes involved in Communities	226
Number of Links involved in Communities	320

Path Summary
Number Of Nodes in MetaPath	150
Number Of Links MetaPath	149
Number of Shortest Paths	784403
Length Of Smallest Path	3
Average Path Length	25.263
Length of Longest Path	61
Minimum Path Strength	1.345
Average Path Strength	7.28125
Maximum Path Strength	24.85
Minimum Path Correlation	0.71
Average Path Correlation	0.98131
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	59.2183
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	55.8805
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component	• protein-containing complex • receptor complex • cell periphery • cellular anatomical structure • plasma membrane • membrane • membrane-bounded organelle • intracellular organelle • intracellular anatomical structure • organelle • intracellular membrane-bounded organelle • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	S
Protein	Receptor
UniProt	Q9NZD1
Sequence	>9IMA_Chain_S G P W G I I L E S L A I L G I V V T I L L L L A F L F L M R K I Q D C S Q W N V L P T Q L L F L L S V L G L F G L A F A F I I E L N Q Q T A P V R Y F L F G V L F A L C F S C L L A H A S N L V K L V R G C V S F S W T T I L C I A I G C S L L Q I I I A T E Y V T L I M T R G M M F V N M T P C Q L N V D F V V L L V Y V L F L M A L T F F V S K A T F C G P C E N W K Q H G R L I F I T V L F S I I I W V V W I S M L L R G N P Q F Q R Q P Q W D D P V V C I A L V T N A W V F L L L Y I V P E L C I L Y R S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q9NZD1
Sequence	>9IMA_Chain_R G P W G I I L E S L A I L G I V V T I L L L L A F L F L M R K I Q D C S Q W N V L P T Q L L F L L S V L G L F G L A F A F I I E L N Q Q T A P V R Y F L F G V L F A L C F S C L L A H A S N L V K L V R G C V S F S W T T I L C I A I G C S L L Q I I I A T E Y V T L I M T R G M M F V N M T P C Q L N V D F V V L L V Y V L F L M A L T F F V S K A T F C G P C E N W K Q H G R L I F I T V L F S I I I W V V W I S M L L R G N P Q F Q R Q P Q W D D P V V C I A L V T N A W V F L L L Y I V P E L C I L Y R S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8YZK	C	Orphan	Orphan	GPRC5D	Homo sapiens	-	-	-	3.4	2024-07-03	doi.org/10.1038/s41467-024-49625-y
	9IMA	C	Orphan	Orphan	GPRC5D	Homo sapiens	Talquetamab	-	-	2.65	2024-09-11	doi.org/10.1016/j.jmb.2024.168748

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Download 9IMA.zip

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