psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:G2	A:A:K10	3.49	No	No	0	6	3
2	A:A:D9	A:A:L5	6.79	No	No	0	4	2
3	A:A:K10	A:A:L5	5.64	No	No	0	3	2
4	A:A:K17	A:A:V13	3.04	No	No	0	4	3
5	A:A:V13	B:B:N88	2.96	No	Yes	0	3	7
6	A:A:R15	B:B:H91	2.26	No	No	0	5	5
7	A:A:S16	B:B:N88	2.98	No	Yes	0	7	7
8	A:A:S16	B:B:K89	6.12	No	Yes	0	7	9
9	A:A:I19	B:B:K89	7.27	No	Yes	0	9	9
10	A:A:I19	B:B:A92	3.25	No	No	0	9	6
11	A:A:D20	B:B:K89	9.68	No	Yes	0	6	9
12	A:A:R21	A:A:R24	4.26	No	No	0	4	3
13	A:A:E25	A:A:R21	5.82	No	No	0	4	4
14	A:A:L23	B:B:I80	2.85	No	No	0	6	8
15	A:A:D26	B:B:K78	2.77	No	No	0	5	8
16	A:A:K29	A:A:R32	2.48	No	No	0	1	4
17	A:A:R32	R:R:K138	6.19	No	No	0	4	4
18	A:A:E33	A:A:K197	16.2	No	Yes	0	6	6
19	A:A:L36	A:A:V34	2.98	No	Yes	0	7	5
20	A:A:L194	A:A:V34	4.47	Yes	Yes	7	4	5
21	A:A:F196	A:A:V34	9.18	Yes	Yes	7	7	5
22	A:A:T219	A:A:V34	4.76	No	Yes	0	7	5
23	A:A:V339	A:A:V34	4.81	No	Yes	7	8	5
24	A:A:F199	A:A:K35	7.44	Yes	No	0	5	9
25	A:A:K35	A:A:V218	4.55	No	No	0	9	9
26	A:A:L36	A:A:M198	2.83	No	No	0	7	7
27	A:A:I222	A:A:L36	4.28	No	No	0	7	7
28	A:A:L37	A:A:L39	5.54	No	Yes	0	9	9
29	A:A:F215	A:A:L37	7.31	Yes	No	0	9	9
30	A:A:I221	A:A:L37	2.85	No	No	0	8	9
31	A:A:K46	A:A:L38	4.23	Yes	No	21	9	8
32	A:A:D200	A:A:L38	4.07	No	No	21	9	8
33	A:A:I222	A:A:L38	2.85	No	No	0	7	8
34	A:A:F223	A:A:L39	4.87	Yes	Yes	3	9	9
35	A:A:I253	A:A:L39	5.71	No	Yes	3	8	9
36	A:A:G40	A:A:S44	1.86	No	No	0	9	9
37	A:A:G40	A:A:K46	6.97	No	Yes	0	9	9
38	A:A:E43	A:A:R242	6.98	No	Yes	0	9	9
39	A:A:G45	A:A:T48	1.82	No	No	0	9	9
40	A:A:G45	A:A:N269	3.39	No	No	0	9	9
41	A:A:D200	A:A:K46	4.15	No	Yes	21	9	9
42	A:A:G202	A:A:K46	1.74	No	Yes	0	9	9
43	A:A:C224	A:A:K46	3.23	No	Yes	0	7	9
44	A:A:C224	A:A:I49	3.27	No	Yes	0	7	7
45	A:A:F267	A:A:I49	6.28	Yes	Yes	10	9	7
46	A:A:I49	A:A:N331	5.66	Yes	Yes	10	7	8
47	A:A:K51	A:A:K54	4.31	No	No	0	9	7
48	A:A:N331	A:A:Q52	10.56	Yes	No	0	8	9
49	A:A:F189	A:A:M53	2.49	No	No	7	9	8
50	A:A:M198	A:A:M53	2.89	No	No	7	7	8
51	A:A:M53	A:A:V332	6.09	No	No	0	8	7
52	A:A:H188	A:A:I55	2.65	No	No	0	3	8
53	A:A:G183	B:B:N119	3.39	No	No	0	9	9
54	A:A:I184	A:A:V201	4.61	No	No	1	9	9
55	A:A:F215	A:A:I184	2.51	Yes	No	1	9	9
56	A:A:I184	B:B:W99	4.7	No	Yes	1	9	9
57	A:A:E186	A:A:K197	2.7	No	Yes	1	9	6
58	A:A:E186	A:A:F199	10.49	No	Yes	1	9	5
59	A:A:F189	A:A:F196	13.93	No	Yes	7	9	7
60	A:A:F189	A:A:M198	4.98	No	No	7	9	7
61	A:A:H195	A:A:T190	4.11	No	No	0	4	3
62	A:A:F191	A:A:K192	8.69	No	No	7	5	4
63	A:A:F191	A:A:V332	9.18	No	No	0	5	7
64	A:A:F191	A:A:F336	3.22	No	Yes	7	5	8
65	A:A:K192	A:A:Q333	5.42	No	No	7	4	5
66	A:A:F336	A:A:K192	14.89	Yes	No	7	8	4
67	A:A:F196	A:A:L194	7.31	Yes	Yes	7	7	4
68	A:A:F336	A:A:L194	3.65	Yes	Yes	7	8	4
69	A:A:L194	R:R:H133	5.14	Yes	Yes	0	4	6
70	A:A:F196	A:A:F336	2.14	Yes	Yes	7	7	8
71	A:A:F196	A:A:V339	3.93	Yes	No	7	7	8
72	A:A:F199	A:A:K197	2.48	Yes	Yes	1	5	6
73	A:A:F199	A:A:F215	4.29	Yes	Yes	1	5	9
74	A:A:F199	B:B:W99	8.02	Yes	Yes	1	5	9
75	A:A:V201	A:A:W211	7.36	No	Yes	1	9	9
76	A:A:F215	A:A:V201	2.62	Yes	No	1	9	9
77	A:A:Q204	A:A:S206	4.33	No	No	1	9	8
78	A:A:Q204	A:A:W211	6.57	No	Yes	1	9	9
79	A:A:Q204	B:B:Y145	2.25	No	Yes	1	9	8
80	A:A:S206	B:B:Y145	5.09	No	Yes	1	8	8
81	A:A:S206	B:B:D186	4.42	No	Yes	1	8	9
82	A:A:E207	A:A:K210	8.1	No	Yes	0	9	9
83	A:A:E207	B:B:D186	5.2	No	Yes	0	9	9
84	A:A:R208	A:A:W211	4	Yes	Yes	0	9	9
85	A:A:I212	A:A:R208	6.26	No	Yes	0	8	9
86	A:A:L249	A:A:R208	3.64	No	Yes	0	9	9
87	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
88	A:A:K210	B:B:M188	5.76	Yes	No	1	9	8
89	A:A:K210	B:B:C204	4.85	Yes	Yes	1	9	7
90	A:A:K210	B:B:D228	9.68	Yes	No	1	9	9
91	A:A:K210	B:B:N230	2.8	Yes	No	0	9	9
92	A:A:F215	A:A:W211	2	Yes	Yes	1	9	9
93	A:A:W211	B:B:L117	2.28	Yes	Yes	1	9	9
94	A:A:W211	B:B:Y145	3.86	Yes	Yes	1	9	8
95	A:A:I212	A:A:W258	2.35	No	Yes	0	8	5
96	A:A:F259	A:A:I212	5.02	Yes	No	0	9	8
97	A:A:C214	A:A:H213	2.95	Yes	Yes	1	7	8
98	A:A:H213	A:A:W258	11.64	Yes	Yes	1	8	5
99	A:A:H213	B:B:Y59	2.18	Yes	Yes	1	8	8
100	A:A:H213	B:B:W332	4.23	Yes	Yes	1	8	9
101	A:A:C214	A:A:F215	2.79	Yes	Yes	1	7	9
102	A:A:C214	B:B:Q75	3.05	Yes	Yes	1	7	9
103	A:A:C214	B:B:W99	2.61	Yes	Yes	1	7	9
104	A:A:F215	A:A:V218	2.62	Yes	No	0	9	9
105	A:A:F215	B:B:W99	12.03	Yes	Yes	1	9	9
106	A:A:E216	A:A:W258	6.54	No	Yes	0	7	5
107	A:A:E216	B:B:K57	4.05	No	No	0	7	9
108	A:A:T219	A:A:V342	3.17	No	No	0	7	7
109	A:A:F259	A:A:I221	8.79	Yes	No	3	9	8
110	A:A:I221	A:A:T262	3.04	No	No	3	8	7
111	A:A:F267	A:A:I222	2.51	Yes	No	0	9	7
112	A:A:F223	A:A:V225	2.62	Yes	Yes	3	9	7
113	A:A:F223	A:A:L249	6.09	Yes	No	0	9	9
114	A:A:F223	A:A:F250	10.72	Yes	Yes	3	9	9
115	A:A:F223	A:A:I253	2.51	Yes	No	3	9	8
116	A:A:F223	A:A:L266	2.44	Yes	Yes	3	9	9
117	A:A:S246	A:A:V225	4.85	No	Yes	0	9	7
118	A:A:L268	A:A:V225	2.98	Yes	Yes	3	8	7
119	A:A:F307	A:A:V225	7.87	Yes	Yes	3	8	7
120	A:A:A226	A:A:K270	3.21	No	No	0	8	9
121	A:A:L227	A:A:L268	6.92	No	Yes	3	7	8
122	A:A:F274	A:A:L227	6.09	Yes	No	3	9	7
123	A:A:F323	A:A:L227	2.44	Yes	No	3	4	7
124	A:A:K270	A:A:S228	3.06	No	No	0	9	9
125	A:A:L273	A:A:S228	6.01	No	No	0	6	9
126	A:A:D229	A:A:L232	10.86	No	No	3	8	8
127	A:A:D229	A:A:R242	9.53	No	Yes	3	8	9
128	A:A:D231	A:A:Y230	24.14	No	Yes	3	9	8
129	A:A:F274	A:A:Y230	5.16	Yes	Yes	3	9	8
130	A:A:K277	A:A:Y230	2.39	No	Yes	3	9	8
131	A:A:I278	A:A:Y230	4.84	Yes	Yes	3	6	8
132	A:A:S281	A:A:Y230	2.54	Yes	Yes	3	7	8
133	A:A:L283	A:A:Y230	2.34	Yes	Yes	3	7	8
134	A:A:D231	A:A:K277	12.44	No	No	3	9	9
135	A:A:D231	A:A:S281	7.36	No	Yes	3	9	7
136	A:A:L232	A:A:R242	14.58	No	Yes	3	8	9
137	A:A:K277	A:A:L232	2.82	No	No	3	9	8
138	A:A:L234	A:A:R242	3.64	No	Yes	0	8	9
139	A:A:A235	A:A:E236	3.02	No	No	0	4	9
140	A:A:H244	A:A:M240	5.25	Yes	No	0	4	6
141	A:A:H244	A:A:N241	12.75	Yes	No	22	4	9
142	A:A:C286	A:A:N241	7.87	No	No	22	6	9
143	A:A:M243	A:A:Y287	4.79	No	Yes	0	8	7
144	A:A:H244	A:A:M247	3.94	Yes	No	0	4	6
145	A:A:C286	A:A:H244	5.9	No	Yes	22	6	4
146	A:A:M247	A:A:Y287	2.39	No	Yes	0	6	7
147	A:A:F307	A:A:M247	4.98	Yes	No	0	8	6
148	A:A:C254	A:A:F250	4.19	Yes	Yes	3	5	9
149	A:A:F250	A:A:I264	3.77	Yes	No	3	9	6
150	A:A:F250	A:A:L266	3.65	Yes	Yes	3	9	9
151	A:A:F250	A:A:L310	2.44	Yes	No	0	9	4
152	A:A:F250	A:A:I319	5.02	Yes	No	0	9	5
153	A:A:D251	A:A:N255	4.04	No	No	3	5	8
154	A:A:D251	A:A:L310	10.86	No	No	0	5	4
155	A:A:D251	A:A:K312	6.91	No	No	3	5	5
156	A:A:F259	A:A:I253	5.02	Yes	No	3	9	8
157	A:A:C254	A:A:I264	3.27	Yes	No	3	5	6
158	A:A:C254	A:A:N311	4.72	Yes	Yes	3	5	8
159	A:A:C254	A:A:K317	3.23	Yes	Yes	3	5	7
160	A:A:K312	A:A:N255	15.39	No	No	3	5	8
161	A:A:N255	A:A:R313	6.03	No	Yes	3	8	4
162	A:A:K257	A:A:N256	2.8	No	No	1	4	8
163	A:A:N256	A:A:W258	4.52	No	Yes	1	8	5
164	A:A:K257	A:A:W258	15.08	No	Yes	1	4	5
165	A:A:F259	A:A:T262	7.78	Yes	No	3	9	7
166	A:A:D261	A:A:T260	7.23	No	No	0	4	3
167	A:A:R313	A:A:T260	5.17	Yes	No	0	4	3
168	A:A:D261	A:A:T316	4.34	No	No	0	4	3
169	A:A:S263	A:A:V342	3.23	No	No	0	7	7
170	A:A:I264	A:A:K317	4.36	No	Yes	3	6	7
171	A:A:F267	A:A:I265	2.51	Yes	Yes	10	9	8
172	A:A:F334	A:A:I265	2.51	Yes	Yes	10	3	8
173	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
174	A:A:F307	A:A:L266	2.44	Yes	Yes	3	8	9
175	A:A:L266	A:A:T321	8.84	Yes	Yes	3	9	5
176	A:A:F267	A:A:H322	6.79	Yes	Yes	10	9	9
177	A:A:F267	A:A:T324	5.19	Yes	Yes	10	9	9
178	A:A:F267	A:A:N331	7.25	Yes	Yes	10	9	8
179	A:A:F267	A:A:F334	2.14	Yes	Yes	10	9	3
180	A:A:F267	A:A:V335	2.62	Yes	No	0	9	8
181	A:A:F307	A:A:L268	2.44	Yes	Yes	3	8	8
182	A:A:L268	A:A:T321	2.95	Yes	Yes	3	8	5
183	A:A:F323	A:A:L268	7.31	Yes	Yes	3	4	8
184	A:A:N269	A:A:T324	4.39	No	Yes	0	9	9
185	A:A:K271	A:A:Y296	11.94	No	No	0	5	4
186	A:A:F323	A:A:K271	8.69	Yes	No	0	4	5
187	A:A:C325	A:A:K271	9.7	No	No	0	7	5
188	A:A:C325	A:A:D272	9.34	No	No	0	7	9
189	A:A:F274	A:A:I278	3.77	Yes	Yes	3	9	6
190	A:A:F274	A:A:Y296	6.19	Yes	No	0	9	4
191	A:A:A299	A:A:F274	2.77	No	Yes	0	7	9
192	A:A:F274	A:A:I303	2.51	Yes	No	0	9	7
193	A:A:E275	A:A:Y296	5.61	No	No	0	5	4
194	A:A:I278	A:A:L283	4.28	Yes	Yes	3	6	7
195	A:A:P282	A:A:S281	3.56	No	Yes	0	5	7
196	A:A:I285	A:A:S281	3.1	No	Yes	0	3	7
197	A:A:P282	A:A:T284	6.99	No	No	0	5	4
198	A:A:N294	A:A:P282	6.52	No	No	0	3	5
199	A:A:L283	A:A:Y290	7.03	Yes	Yes	0	7	7
200	A:A:L283	A:A:N294	2.75	Yes	No	0	7	3
201	A:A:A299	A:A:L283	3.15	No	Yes	0	7	7
202	A:A:C286	A:A:Y287	5.38	No	Yes	0	6	7
203	A:A:Y287	A:A:Y302	4.96	Yes	No	0	7	6
204	A:A:I303	A:A:Y287	3.63	No	Yes	0	7	7
205	A:A:G292	A:A:Y290	5.79	No	Yes	0	7	7
206	A:A:E298	A:A:Y290	6.73	No	Yes	0	4	7
207	A:A:Y290	A:A:Y302	16.88	Yes	No	0	7	6
208	A:A:E298	A:A:S293	2.87	No	No	0	4	3
209	A:A:E297	A:A:T295	2.82	No	No	0	4	5
210	A:A:E298	A:A:T295	11.29	No	No	0	4	5
211	A:A:A300	A:A:F323	2.77	No	Yes	0	5	4
212	A:A:Q306	A:A:Y302	3.38	No	No	0	5	6
213	A:A:F307	A:A:I303	2.51	Yes	No	0	8	7
214	A:A:E308	A:A:Q304	5.1	No	No	3	3	5
215	A:A:Q304	A:A:T321	11.34	No	Yes	3	5	5
216	A:A:F323	A:A:Q304	3.51	Yes	No	3	4	5
217	A:A:E308	A:A:I319	6.83	No	No	0	3	5
218	A:A:E308	A:A:T321	5.64	No	Yes	3	3	5
219	A:A:N311	A:A:R313	2.41	Yes	Yes	3	8	4
220	A:A:K317	A:A:N311	2.8	Yes	Yes	3	7	8
221	A:A:I319	A:A:N311	5.66	No	Yes	0	5	8
222	A:A:K317	A:A:R313	4.95	Yes	Yes	3	7	4
223	A:A:D315	R:R:K225	2.77	No	No	0	3	5
224	A:A:E318	A:A:Y320	8.98	No	No	0	4	7
225	A:A:E318	A:A:K345	4.05	No	No	0	4	5
226	A:A:E318	R:R:H223	3.69	No	No	0	4	4
227	A:A:F334	A:A:Y320	2.06	Yes	No	0	3	7
228	A:A:A338	A:A:Y320	5.34	No	No	0	6	7
229	A:A:H322	A:A:T324	2.74	Yes	Yes	10	9	9
230	A:A:H322	A:A:K330	2.62	Yes	No	0	9	4
231	A:A:H322	A:A:N331	3.83	Yes	Yes	10	9	8
232	A:A:F334	A:A:H322	12.44	Yes	Yes	10	3	9
233	A:A:T324	A:A:T327	4.71	Yes	No	10	9	8
234	A:A:N331	A:A:T324	8.77	Yes	Yes	10	8	9
235	A:A:K330	A:A:T327	4.5	No	No	0	4	8
236	A:A:N331	A:A:T327	4.39	Yes	No	10	8	8
237	A:A:F336	A:A:Q333	2.34	Yes	No	7	8	5
238	A:A:D337	A:A:Q333	11.75	No	No	0	4	5
239	A:A:F336	A:A:T340	6.49	Yes	Yes	7	8	6
240	A:A:I343	A:A:V339	3.07	No	No	0	7	8
241	A:A:D341	A:A:T340	2.89	No	Yes	7	8	6
242	A:A:I344	A:A:T340	3.04	Yes	Yes	7	6	6
243	A:A:T340	R:R:H133	5.48	Yes	Yes	0	6	6
244	A:A:T340	R:R:R218	5.17	Yes	Yes	7	6	5
245	A:A:D341	R:R:R218	3.57	No	Yes	7	8	5
246	A:A:D341	R:R:M220	5.54	No	Yes	7	8	3
247	A:A:N346	A:A:V342	4.43	No	No	0	4	7
248	A:A:I343	A:A:N347	4.25	No	No	0	7	8
249	A:A:I343	R:R:H133	7.95	No	Yes	0	7	6
250	A:A:I344	R:R:P132	5.08	Yes	No	0	6	8
251	A:A:I344	R:R:R218	3.76	Yes	Yes	7	6	5
252	A:A:I344	R:R:M220	5.83	Yes	Yes	7	6	3
253	A:A:K345	R:R:M220	5.76	No	Yes	0	5	3
254	A:A:N347	R:R:R128	3.62	No	Yes	9	8	8
255	A:A:N347	R:R:N137	2.72	No	No	9	8	4
256	A:A:L348	A:A:L353	4.15	No	Yes	0	9	7
257	A:A:F354	A:A:L348	9.74	Yes	No	23	5	9
258	A:A:L348	R:R:I226	2.85	No	Yes	23	9	6
259	A:A:F354	A:A:K349	7.44	Yes	No	0	5	5
260	A:A:D350	R:R:K60	5.53	No	No	0	4	7
261	A:A:D350	R:R:R128	3.57	No	Yes	0	4	8
262	A:A:L353	R:R:R125	7.29	Yes	No	0	7	9
263	A:A:L353	R:R:I233	2.85	Yes	Yes	0	7	7
264	A:A:F354	R:R:K225	6.2	Yes	No	0	5	5
265	A:A:F354	R:R:I226	6.28	Yes	Yes	23	5	6
266	B:B:E3	B:B:Q6	5.1	No	No	0	5	1
267	B:B:D5	B:B:L4	2.71	No	Yes	0	1	4
268	B:B:L4	B:B:R8	8.5	Yes	No	0	4	3
269	B:B:L4	G:G:S8	3	Yes	No	0	4	4
270	B:B:L7	G:G:A12	4.73	No	No	0	8	5
271	B:B:E12	B:B:Q9	5.1	No	No	0	4	3
272	B:B:E10	G:G:K20	4.05	No	No	0	8	6
273	B:B:L14	B:B:Q13	3.99	Yes	No	0	8	1
274	B:B:L14	B:B:Q17	2.66	Yes	No	0	8	4
275	B:B:L14	G:G:L19	4.15	Yes	Yes	0	8	9
276	B:B:L14	G:G:K20	8.46	Yes	No	0	8	6
277	B:B:K15	G:G:L19	2.82	No	Yes	0	6	9
278	B:B:N16	B:B:R19	8.44	No	No	0	1	4
279	B:B:Q17	G:G:A23	4.55	No	No	0	4	8
280	B:B:I18	B:B:R22	2.51	No	Yes	0	7	6
281	B:B:I18	G:G:A23	3.25	No	No	0	7	8
282	B:B:D20	B:B:R19	11.91	No	No	0	2	4
283	B:B:A21	G:G:R27	5.53	No	No	0	4	8
284	B:B:D258	B:B:R22	20.25	No	Yes	25	7	6
285	B:B:Q259	B:B:R22	5.84	No	Yes	0	6	6
286	B:B:R22	G:G:R27	2.13	Yes	No	25	6	8
287	B:B:C25	B:B:Q259	3.05	No	No	0	3	6
288	B:B:D27	G:G:K29	11.06	No	No	0	8	4
289	B:B:D27	G:G:S31	2.94	No	No	0	8	9
290	B:B:A28	B:B:Q32	4.55	No	No	0	4	1
291	B:B:Q32	B:B:T29	2.83	No	No	0	1	3
292	B:B:L30	B:B:T34	5.9	No	Yes	2	5	5
293	B:B:L30	B:B:M262	5.65	No	Yes	2	5	4
294	B:B:L30	B:B:L300	2.77	No	No	2	5	6
295	B:B:I33	B:B:T34	3.04	No	Yes	0	3	5
296	B:B:I33	G:G:A34	3.25	No	No	0	3	6
297	B:B:I33	G:G:M38	4.37	No	No	0	3	4
298	B:B:I37	B:B:T34	3.04	No	Yes	0	2	5
299	B:B:L300	B:B:T34	7.37	No	Yes	2	6	5
300	B:B:I37	B:B:R283	6.26	No	No	0	2	9
301	B:B:D38	B:B:P39	3.22	No	No	0	1	1
302	B:B:K301	B:B:P39	5.02	Yes	No	0	5	1
303	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
304	B:B:I43	B:B:V40	3.07	No	Yes	0	3	3
305	B:B:V40	G:G:L51	4.47	Yes	Yes	0	3	6
306	B:B:Q44	B:B:R42	9.35	No	No	0	4	2
307	B:B:G306	B:B:R42	6	No	No	0	4	2
308	B:B:I43	B:B:M45	4.37	No	No	0	3	4
309	B:B:Q44	B:B:R46	5.84	No	No	0	4	5
310	B:B:L308	B:B:M45	4.24	No	No	12	7	4
311	B:B:M45	B:B:W339	5.82	No	Yes	12	4	9
312	B:B:R46	B:B:R48	4.26	No	No	0	5	7
313	B:B:K337	B:B:T47	7.51	Yes	No	12	6	3
314	B:B:T47	B:B:W339	4.85	No	Yes	12	3	9
315	B:B:N340	B:B:R48	8.44	No	No	5	9	7
316	B:B:R48	G:G:F61	2.14	No	Yes	5	7	8
317	B:B:R49	B:B:T87	5.17	No	No	0	7	5
318	B:B:I338	B:B:R49	6.26	No	No	5	5	7
319	B:B:R49	G:G:F61	7.48	No	Yes	5	7	8
320	B:B:R52	B:B:T50	5.17	No	No	0	7	3
321	B:B:K337	B:B:T50	4.5	Yes	No	0	6	3
322	B:B:L51	B:B:W82	15.94	Yes	Yes	5	9	9
323	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
324	B:B:L336	B:B:L51	6.92	Yes	Yes	5	7	9
325	B:B:I338	B:B:L51	4.28	No	Yes	5	5	9
326	B:B:F335	B:B:R52	2.14	No	No	0	4	7
327	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
328	B:B:H54	B:B:S72	5.58	Yes	No	0	9	9
329	B:B:H54	B:B:S74	15.34	Yes	No	0	9	9
330	B:B:H54	B:B:I80	11.93	Yes	No	0	9	8
331	B:B:D76	B:B:L55	6.79	No	No	0	9	6
332	B:B:K57	B:B:Y59	2.39	No	Yes	1	9	8
333	B:B:K57	B:B:W332	24.37	No	Yes	1	9	9
334	B:B:G330	B:B:I58	1.76	No	No	5	5	9
335	B:B:I58	B:B:L336	2.85	No	Yes	5	9	7
336	B:B:Q75	B:B:Y59	13.53	Yes	Yes	1	9	8
337	B:B:W332	B:B:Y59	5.79	Yes	Yes	1	9	8
338	B:B:A60	B:B:C103	1.81	No	No	0	7	8
339	B:B:M61	B:B:W63	3.49	Yes	Yes	5	6	7
340	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
341	B:B:G319	B:B:M61	1.75	No	Yes	5	5	6
342	B:B:L336	B:B:M61	2.83	Yes	Yes	5	7	6
343	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
344	B:B:H62	B:B:R150	12.41	No	No	0	6	6
345	B:B:L70	B:B:W63	4.56	No	Yes	5	5	7
346	B:B:S84	B:B:W63	6.18	No	Yes	5	5	7
347	B:B:G319	B:B:W63	2.81	No	Yes	5	5	7
348	B:B:T321	B:B:W63	10.92	Yes	Yes	5	7	7
349	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
350	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
351	B:B:D66	B:B:R68	3.57	No	No	0	8	5
352	B:B:D66	B:B:L69	5.43	No	No	0	8	5
353	B:B:S67	B:B:T321	4.8	No	Yes	5	5	7
354	B:B:D322	B:B:S67	4.42	No	No	0	1	5
355	B:B:D323	B:B:S67	10.31	No	No	5	7	5
356	B:B:D83	B:B:R68	13.1	No	No	0	8	5
357	B:B:R68	B:B:Y85	26.75	No	No	0	5	4
358	B:B:L69	B:B:Y105	2.34	No	Yes	0	5	6
359	B:B:L70	B:B:W82	4.56	No	Yes	5	5	9
360	B:B:L70	B:B:S84	4.5	No	No	5	5	5
361	B:B:I81	B:B:V71	3.07	Yes	No	0	7	8
362	B:B:V71	B:B:Y105	3.79	No	Yes	0	8	6
363	B:B:S72	B:B:W82	3.71	No	Yes	5	9	9
364	B:B:L336	B:B:S72	3	Yes	No	5	7	9
365	B:B:A73	B:B:C103	3.61	No	No	0	9	8
366	B:B:Q75	B:B:W99	4.38	Yes	Yes	1	9	9
367	B:B:D76	B:B:K78	2.77	No	No	0	9	8
368	B:B:I93	B:B:L79	5.71	Yes	No	0	7	7
369	B:B:C114	B:B:L79	4.76	Yes	No	0	8	7
370	B:B:I80	B:B:W82	11.74	No	Yes	0	8	9
371	B:B:I81	B:B:V90	3.07	Yes	No	8	7	5
372	B:B:H91	B:B:I81	6.63	No	Yes	8	5	7
373	B:B:I81	B:B:L126	4.28	Yes	Yes	8	7	5
374	B:B:K89	B:B:W82	12.76	Yes	Yes	0	9	9
375	B:B:L336	B:B:W82	4.56	Yes	Yes	5	7	9
376	B:B:D83	B:B:T86	7.23	No	No	20	8	6
377	B:B:D83	B:B:N88	4.04	No	Yes	20	8	7
378	B:B:S84	G:G:F61	2.64	No	Yes	5	5	8
379	B:B:Y85	G:G:P60	13.91	No	No	5	4	9
380	B:B:Y85	G:G:F61	7.22	No	Yes	5	4	8
381	B:B:N88	B:B:T86	10.24	Yes	No	20	7	6
382	B:B:H91	B:B:V90	5.54	No	No	8	5	5
383	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
384	B:B:I93	B:B:Y124	3.63	Yes	Yes	8	7	6
385	B:B:I93	B:B:V133	4.61	Yes	No	8	7	4
386	B:B:L95	B:B:V100	4.47	Yes	No	8	8	9
387	B:B:C114	B:B:L95	4.76	Yes	Yes	8	8	8
388	B:B:L95	B:B:Y124	3.52	Yes	Yes	8	8	6
389	B:B:R96	B:B:V135	3.92	No	No	0	6	4
390	B:B:E138	B:B:R96	6.98	No	No	0	6	6
391	B:B:D118	B:B:S97	8.83	No	No	0	9	8
392	B:B:L117	B:B:W99	5.69	Yes	Yes	1	9	9
393	B:B:C114	B:B:V100	5.12	Yes	No	8	8	9
394	B:B:G116	B:B:M101	3.49	No	No	0	9	9
395	B:B:L117	B:B:M101	2.83	Yes	No	1	9	9
396	B:B:M101	B:B:Y145	3.59	No	Yes	1	9	8
397	B:B:G115	B:B:T102	1.82	No	No	0	9	8
398	B:B:C149	B:B:T102	3.38	Yes	No	0	8	8
399	B:B:A104	B:B:A113	1.79	No	No	1	7	9
400	B:B:A104	B:B:C149	1.81	No	Yes	1	7	8
401	B:B:A104	B:B:F151	2.77	No	Yes	1	7	9
402	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
403	B:B:V112	B:B:Y105	2.52	No	Yes	8	8	6
404	B:B:L126	B:B:Y105	3.52	Yes	Yes	8	5	6
405	B:B:A106	B:B:P107	1.87	No	No	0	6	6
406	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
407	B:B:G109	B:B:S108	1.86	No	No	0	5	6
408	B:B:N110	B:B:S108	7.45	No	No	0	4	6
409	B:B:D154	B:B:S108	4.42	No	No	0	6	6
410	B:B:N110	B:B:Y111	3.49	No	Yes	0	4	4
411	B:B:K127	B:B:N110	6.99	No	No	0	4	4
412	B:B:N125	B:B:Y111	15.12	No	Yes	0	4	4
413	B:B:S136	B:B:Y111	2.54	No	Yes	0	4	4
414	B:B:F151	B:B:Y111	2.06	Yes	Yes	0	9	4
415	B:B:D154	B:B:Y111	8.05	No	Yes	0	6	4
416	B:B:V112	B:B:Y124	3.79	No	Yes	8	8	6
417	B:B:L126	B:B:V112	5.96	Yes	No	8	5	8
418	B:B:A113	B:B:C149	1.81	No	Yes	1	9	8
419	B:B:A113	B:B:F151	2.77	No	Yes	1	9	9
420	B:B:C114	B:B:G115	3.92	Yes	No	0	8	9
421	B:B:G115	B:B:G116	2.11	No	No	0	9	9
422	B:B:L117	B:B:Y145	4.69	Yes	Yes	1	9	8
423	B:B:D118	B:B:I120	2.8	No	No	0	9	6
424	B:B:G144	B:B:N119	3.39	No	No	0	8	9
425	B:B:E138	B:B:I120	4.1	No	No	0	6	6
426	B:B:C121	B:B:L139	3.17	No	No	0	8	9
427	B:B:C121	B:B:C149	1.82	No	Yes	0	8	8
428	B:B:C121	B:B:T159	3.38	No	Yes	0	8	9
429	B:B:S122	B:B:Y124	3.82	No	Yes	0	8	6
430	B:B:E138	B:B:S122	4.31	No	No	0	6	8
431	B:B:I123	B:B:R137	2.51	No	No	0	6	5
432	B:B:F151	B:B:I123	2.51	Yes	No	0	9	6
433	B:B:V133	B:B:Y124	2.52	No	Yes	8	4	6
434	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
435	B:B:N125	B:B:T128	4.39	No	Yes	27	4	3
436	B:B:N125	B:B:R134	9.64	No	No	27	4	3
437	B:B:L126	B:B:V133	2.98	Yes	No	8	5	4
438	B:B:E130	B:B:T128	2.82	No	Yes	0	3	3
439	B:B:R134	B:B:T128	3.88	No	Yes	27	3	3
440	B:B:E130	B:B:R129	2.33	No	No	0	3	3
441	B:B:R134	B:B:S136	3.95	No	No	0	3	4
442	B:B:I171	B:B:R137	2.51	No	No	0	6	5
443	B:B:G174	B:B:R137	3	No	No	0	4	5
444	B:B:L139	B:B:W169	19.36	No	Yes	0	9	8
445	B:B:H142	B:B:L146	6.43	Yes	No	1	9	7
446	B:B:H142	B:B:T159	4.11	Yes	Yes	1	9	9
447	B:B:H142	B:B:S161	16.74	Yes	No	1	9	9
448	B:B:D163	B:B:H142	8.82	Yes	Yes	1	9	9
449	B:B:H142	B:B:T165	5.48	Yes	No	1	9	7
450	B:B:A167	B:B:H142	2.93	No	Yes	1	4	9
451	B:B:H142	B:B:W169	2.12	Yes	Yes	1	9	8
452	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
453	B:B:G144	B:B:G162	2.11	No	Yes	0	8	9
454	B:B:G162	B:B:Y145	7.24	Yes	Yes	1	9	8
455	B:B:D186	B:B:Y145	5.75	Yes	Yes	1	9	8
456	B:B:M188	B:B:Y145	4.79	No	Yes	1	8	8
457	B:B:L146	B:B:T159	4.42	No	Yes	1	7	9
458	B:B:S147	B:B:S160	4.89	No	No	0	9	6
459	B:B:C148	B:B:L190	6.35	No	Yes	0	6	5
460	B:B:L190	B:B:R150	2.43	Yes	No	0	5	6
461	B:B:L192	B:B:R150	2.43	No	No	0	5	6
462	B:B:F151	B:B:I157	7.54	Yes	No	1	9	7
463	B:B:F151	B:B:I171	2.51	Yes	No	1	9	6
464	B:B:L152	B:B:Q156	6.65	No	No	0	3	5
465	B:B:L152	B:B:L192	4.15	No	No	0	3	5
466	B:B:L152	B:B:T196	4.42	No	No	0	3	1
467	B:B:D153	B:B:Q156	14.36	No	No	0	5	5
468	B:B:D170	B:B:N155	5.39	No	No	14	9	3
469	B:B:E172	B:B:N155	6.57	No	No	14	6	3
470	B:B:I157	B:B:W169	3.52	No	Yes	1	7	8
471	B:B:I157	B:B:I171	5.89	No	No	1	7	6
472	B:B:L190	B:B:V158	2.98	Yes	No	0	5	5
473	B:B:L192	B:B:V158	4.47	No	No	0	5	5
474	B:B:F199	B:B:V158	3.93	Yes	No	0	9	5
475	B:B:T159	B:B:W169	8.49	Yes	Yes	1	9	8
476	B:B:S160	B:B:V187	4.85	No	No	0	6	9
477	B:B:L190	B:B:S160	3	Yes	No	0	5	6
478	B:B:G162	B:B:S161	3.71	Yes	No	1	9	9
479	B:B:D163	B:B:S161	8.83	Yes	No	1	9	9
480	B:B:D186	B:B:G162	3.35	Yes	Yes	1	9	9
481	B:B:D163	B:B:T165	10.12	Yes	No	1	9	7
482	B:B:G185	B:B:T164	1.82	No	No	0	5	6
483	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
484	B:B:C166	B:B:S201	3.44	No	No	0	8	9
485	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
486	B:B:A167	B:B:Q176	6.06	No	Yes	1	4	4
487	B:B:L168	B:B:T178	4.42	No	Yes	0	6	4
488	B:B:L168	B:B:V213	2.98	No	No	0	6	4
489	B:B:Q176	B:B:W169	14.24	Yes	Yes	1	4	8
490	B:B:D170	B:B:E172	2.6	No	No	14	9	6
491	B:B:D170	B:B:T173	4.34	No	No	14	9	5
492	B:B:G174	B:B:T173	1.82	No	No	14	4	5
493	B:B:Q175	B:B:T173	4.25	No	No	14	4	5
494	B:B:G174	B:B:Q175	3.29	No	No	14	4	4
495	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
496	B:B:T177	B:B:T178	3.14	No	Yes	0	4	4
497	B:B:F180	B:B:T178	6.49	Yes	Yes	6	7	4
498	B:B:G216	B:B:T178	1.82	No	Yes	6	4	4
499	B:B:F180	B:B:F199	7.5	Yes	Yes	6	7	9
500	B:B:F180	B:B:W211	14.03	Yes	Yes	6	7	8
501	B:B:F180	B:B:G216	4.52	Yes	No	6	7	4
502	B:B:G182	B:B:T181	1.82	No	No	0	6	2
503	B:B:G182	B:B:K209	1.74	No	Yes	0	6	6
504	B:B:H183	B:B:V187	5.54	Yes	No	6	9	9
505	B:B:H183	B:B:S201	4.18	Yes	No	6	9	9
506	B:B:A203	B:B:H183	5.85	No	Yes	6	8	9
507	B:B:D205	B:B:H183	6.3	Yes	Yes	6	9	9
508	B:B:H183	B:B:K209	13.1	Yes	Yes	6	9	6
509	B:B:H183	B:B:W211	4.23	Yes	Yes	6	9	8
510	B:B:G185	B:B:T184	1.82	No	No	0	5	3
511	B:B:D205	B:B:T184	5.78	Yes	No	0	9	3
512	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
513	B:B:A203	B:B:V187	3.39	No	No	6	8	9
514	B:B:C204	B:B:M188	4.86	Yes	No	1	7	8
515	B:B:G202	B:B:S189	1.86	No	No	0	6	7
516	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
517	B:B:S191	B:B:V200	3.23	No	Yes	2	8	6
518	B:B:I232	B:B:S191	3.1	Yes	No	2	8	8
519	B:B:F234	B:B:S191	5.28	No	No	2	5	8
520	B:B:A193	B:B:P194	1.87	No	No	0	4	4
521	B:B:A193	B:B:F234	2.77	No	No	0	4	5
522	B:B:G238	B:B:P194	4.06	No	No	0	7	4
523	B:B:D195	B:B:R197	4.76	No	No	0	5	5
524	B:B:L198	B:B:L210	5.54	No	Yes	0	3	5
525	B:B:D212	B:B:L198	2.71	Yes	No	0	9	3
526	B:B:F199	B:B:W211	13.03	Yes	Yes	6	9	8
527	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
528	B:B:L210	B:B:V200	2.98	Yes	Yes	0	5	6
529	B:B:I232	B:B:V200	4.61	Yes	Yes	2	8	6
530	B:B:F234	B:B:V200	9.18	No	Yes	2	5	6
531	B:B:F241	B:B:V200	6.55	Yes	Yes	2	6	6
532	B:B:S201	B:B:W211	6.18	No	Yes	6	9	8
533	B:B:G202	B:B:I229	3.53	No	No	0	6	7
534	B:B:A203	B:B:D205	3.09	No	Yes	6	8	9
535	B:B:C204	B:B:D228	9.34	Yes	No	1	7	9
536	B:B:D205	B:B:S207	5.89	Yes	No	0	9	5
537	B:B:A208	B:B:F222	2.77	No	Yes	2	6	8
538	B:B:A208	B:B:F241	2.77	No	Yes	2	6	6
539	B:B:K209	B:B:W211	9.28	Yes	Yes	6	6	8
540	B:B:C218	B:B:K209	6.47	Yes	Yes	6	5	6
541	B:B:K209	B:B:T221	4.5	Yes	No	0	6	7
542	B:B:L210	B:B:R219	2.43	Yes	No	0	5	5
543	B:B:L210	B:B:Q220	3.99	Yes	Yes	0	5	7
544	B:B:C218	B:B:W211	5.22	Yes	Yes	6	5	8
545	B:B:D212	B:B:R214	2.38	Yes	No	0	9	9
546	B:B:D212	B:B:E215	12.99	Yes	Yes	6	9	3
547	B:B:D212	B:B:R219	9.53	Yes	No	6	9	5
548	B:B:R214	B:B:V213	2.62	No	No	0	9	4
549	B:B:E215	B:B:G216	3.27	Yes	No	6	3	4
550	B:B:E215	B:B:M217	6.77	Yes	No	0	3	3
551	B:B:E215	B:B:R219	13.96	Yes	No	6	3	5
552	B:B:M217	G:G:Q18	5.44	No	Yes	0	3	9
553	B:B:C218	G:G:Q18	3.05	Yes	Yes	6	5	9
554	B:B:C218	G:G:E22	3.04	Yes	Yes	6	5	9
555	B:B:F222	B:B:Q220	8.2	Yes	Yes	0	8	7
556	B:B:D258	B:B:Q220	5.22	No	Yes	0	7	7
557	B:B:Q220	G:G:I25	4.12	Yes	No	0	7	2
558	B:B:T221	G:G:E22	7.06	No	Yes	0	7	9
559	B:B:F222	B:B:F241	10.72	Yes	Yes	2	8	6
560	B:B:F222	B:B:F253	6.43	Yes	Yes	2	8	6
561	B:B:G224	B:B:T223	1.82	No	No	0	6	2
562	B:B:H225	B:B:I229	6.63	Yes	No	2	9	7
563	B:B:H225	B:B:T243	6.85	Yes	Yes	2	9	8
564	B:B:H225	B:B:S245	13.95	Yes	No	2	9	9
565	B:B:D247	B:B:H225	2.52	Yes	Yes	2	9	9
566	B:B:H225	B:B:T249	2.74	Yes	Yes	2	9	6
567	B:B:H225	B:B:R251	22.57	Yes	Yes	2	9	8
568	B:B:F253	B:B:H225	3.39	Yes	Yes	2	6	9
569	B:B:D247	B:B:E226	7.8	Yes	No	0	9	3
570	B:B:D247	B:B:S227	4.42	Yes	No	0	9	6
571	B:B:D228	B:B:D246	5.32	No	No	0	9	9
572	B:B:I229	B:B:T243	3.04	No	Yes	2	7	8
573	B:B:D246	B:B:N230	5.39	No	No	0	9	9
574	B:B:A231	B:B:V276	3.39	No	No	0	5	6
575	B:B:F241	B:B:I232	5.02	Yes	Yes	2	6	8
576	B:B:I232	B:B:T243	3.04	Yes	Yes	2	8	8
577	B:B:F235	B:B:P236	10.11	Yes	Yes	15	6	7
578	B:B:F235	B:B:N237	2.42	Yes	No	15	6	5
579	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
580	B:B:F235	B:B:F278	6.43	Yes	Yes	15	6	7
581	B:B:F235	B:B:G282	4.52	Yes	No	15	6	9
582	B:B:F235	G:G:L37	7.31	Yes	No	0	6	7
583	B:B:F235	G:G:Y40	5.16	Yes	Yes	15	6	6
584	B:B:F278	B:B:P236	2.89	Yes	Yes	15	7	7
585	B:B:G282	B:B:P236	4.06	No	Yes	15	9	7
586	B:B:P236	G:G:Y40	4.17	Yes	Yes	15	7	6
587	B:B:N237	G:G:Y40	12.79	No	Yes	15	5	6
588	B:B:N239	B:B:R256	3.62	No	No	0	2	9
589	B:B:F241	B:B:T243	2.59	Yes	Yes	2	6	8
590	B:B:F241	B:B:F253	12.86	Yes	Yes	2	6	6
591	B:B:F241	B:B:L255	2.44	Yes	No	0	6	6
592	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
593	B:B:G244	B:B:T243	1.82	Yes	Yes	2	5	8
594	B:B:F253	B:B:T243	7.78	Yes	Yes	2	6	8
595	B:B:C250	B:B:G244	1.96	Yes	Yes	2	8	5
596	B:B:G244	B:B:I273	3.53	Yes	Yes	2	5	6
597	B:B:G244	B:B:V276	1.84	Yes	No	0	5	6
598	B:B:D247	B:B:S245	8.83	Yes	No	2	9	9
599	B:B:D247	B:B:T249	7.23	Yes	Yes	2	9	6
600	B:B:R251	B:B:T249	10.35	Yes	Yes	2	8	6
601	B:B:S265	B:B:T249	3.2	No	Yes	0	2	6
602	B:B:C250	B:B:Y264	2.69	Yes	Yes	2	8	5
603	B:B:C250	B:B:I273	4.91	Yes	Yes	2	8	6
604	B:B:A287	B:B:C250	1.81	No	Yes	2	6	8
605	B:B:F253	B:B:R251	3.21	Yes	Yes	2	6	8
606	B:B:E260	B:B:R251	11.63	No	Yes	2	6	8
607	B:B:R251	B:B:T263	3.88	Yes	No	2	8	1
608	B:B:L252	B:B:L261	8.3	No	No	0	7	5
609	B:B:E260	B:B:F253	2.33	No	Yes	2	6	6
610	B:B:D254	B:B:L261	12.21	No	No	0	9	5
611	B:B:D254	G:G:A33	4.63	No	No	0	9	7
612	B:B:R256	G:G:I28	8.77	No	No	0	9	4
613	B:B:R256	G:G:D36	5.96	No	No	0	9	5
614	B:B:D258	G:G:R27	11.91	No	No	25	7	8
615	B:B:E260	B:B:T263	2.82	No	No	2	6	1
616	B:B:M262	B:B:Y264	7.18	Yes	Yes	2	4	5
617	B:B:A302	B:B:M262	4.83	No	Yes	2	2	4
618	B:B:S265	B:B:T263	3.2	No	No	0	2	1
619	B:B:L285	B:B:Y264	2.34	Yes	Yes	0	6	5
620	B:B:W297	B:B:Y264	4.82	Yes	Yes	2	8	5
621	B:B:A302	B:B:Y264	2.67	No	Yes	2	2	5
622	B:B:H266	B:B:N268	3.83	Yes	No	0	4	4
623	B:B:H266	B:B:I269	2.65	Yes	Yes	0	4	4
624	B:B:H266	B:B:R304	5.64	Yes	Yes	0	4	5
625	B:B:I269	B:B:Y289	4.84	Yes	Yes	2	4	7
626	B:B:I269	B:B:W297	2.35	Yes	Yes	2	4	8
627	B:B:C271	B:B:G272	1.96	No	No	2	5	4
628	B:B:C271	B:B:D290	7.78	No	No	2	5	6
629	B:B:C271	B:B:D291	4.67	No	No	0	5	8
630	B:B:G272	B:B:I273	1.76	No	Yes	2	4	6
631	B:B:D290	B:B:G272	3.35	No	No	2	6	4
632	B:B:I273	B:B:Y289	7.25	Yes	Yes	2	6	7
633	B:B:S275	B:B:T274	4.8	No	No	0	8	8
634	B:B:G288	B:B:T274	1.82	No	No	0	7	8
635	B:B:R314	B:B:T274	2.59	No	No	0	8	8
636	B:B:L318	B:B:S275	3	Yes	No	0	6	8
637	B:B:L285	B:B:V276	2.98	Yes	No	0	6	6
638	B:B:L318	B:B:S277	3	Yes	No	0	6	5
639	B:B:G319	B:B:S277	1.86	No	No	0	5	5
640	B:B:S277	B:B:V320	4.85	No	No	0	5	7
641	B:B:F278	B:B:L285	4.87	Yes	Yes	0	7	6
642	B:B:G282	B:B:S279	1.86	No	No	0	9	9
643	B:B:L284	B:B:S279	4.5	No	No	0	5	9
644	B:B:S279	G:G:D48	2.94	No	No	0	9	9
645	B:B:G324	B:B:K280	1.74	No	No	0	9	1
646	B:B:K280	G:G:E47	2.7	No	No	0	1	3
647	B:B:S281	G:G:D48	11.78	No	No	0	9	9
648	B:B:D298	B:B:R283	10.72	No	No	0	9	9
649	B:B:R283	G:G:L51	7.29	No	Yes	0	9	6
650	B:B:L284	B:B:V296	2.98	No	No	0	5	5
651	B:B:L284	G:G:L51	2.77	No	Yes	0	5	6
652	B:B:L286	B:B:V296	4.47	No	No	0	7	5
653	B:B:L286	B:B:L318	4.15	No	Yes	0	7	6
654	B:B:L286	B:B:V327	4.47	No	No	0	7	6
655	B:B:A287	B:B:Y289	5.34	No	Yes	2	6	7
656	B:B:A287	B:B:W297	2.59	No	Yes	2	6	8
657	B:B:G288	B:B:V315	3.68	No	No	0	7	7
658	B:B:D291	B:B:Y289	4.6	No	Yes	0	8	7
659	B:B:N295	B:B:Y289	8.14	Yes	Yes	2	6	7
660	B:B:W297	B:B:Y289	2.89	Yes	Yes	2	8	7
661	B:B:D290	B:B:R314	13.1	No	No	0	6	8
662	B:B:D291	B:B:N293	10.77	No	Yes	0	8	5
663	B:B:F292	B:B:N313	4.83	No	No	0	4	7
664	B:B:N293	B:B:N295	2.72	Yes	Yes	0	5	6
665	B:B:N293	B:B:V307	2.96	Yes	No	0	5	3
666	B:B:A309	B:B:N293	3.13	No	Yes	0	3	5
667	B:B:C294	B:B:L308	6.35	No	No	0	5	7
668	B:B:C294	B:B:L318	3.17	No	Yes	0	5	6
669	B:B:N295	B:B:W297	6.78	Yes	Yes	2	6	8
670	B:B:N295	B:B:R304	15.67	Yes	Yes	2	6	5
671	B:B:G306	B:B:V296	1.84	No	No	0	4	5
672	B:B:R304	B:B:W297	3	Yes	Yes	2	5	8
673	B:B:D298	B:B:K301	5.53	No	Yes	26	9	5
674	B:B:D298	B:B:D303	3.99	No	No	26	9	2
675	B:B:L300	G:G:C41	4.76	No	No	0	6	7
676	B:B:D303	B:B:K301	5.53	No	Yes	26	2	5
677	B:B:R304	B:B:V307	2.62	Yes	No	0	5	3
678	B:B:L308	B:B:W339	21.64	No	Yes	12	7	9
679	B:B:H311	B:B:V315	4.15	Yes	No	0	9	7
680	B:B:H311	B:B:T329	6.85	Yes	No	0	9	8
681	B:B:H311	B:B:S331	13.95	Yes	No	12	9	9
682	B:B:D333	B:B:H311	8.82	Yes	Yes	12	9	9
683	B:B:H311	B:B:K337	3.93	Yes	Yes	12	9	6
684	B:B:D312	B:B:D333	3.99	No	Yes	0	5	9
685	B:B:N313	B:B:W332	6.78	No	Yes	0	7	9
686	B:B:R314	B:B:W332	20.99	No	Yes	0	8	9
687	B:B:C317	B:B:S316	3.44	No	No	0	7	9
688	B:B:S316	B:B:W332	3.71	No	Yes	0	9	9
689	B:B:C317	B:B:G330	1.96	No	No	0	7	5
690	B:B:L318	B:B:T329	2.95	Yes	No	0	6	8
691	B:B:D323	B:B:T321	5.78	No	Yes	5	7	7
692	B:B:G324	B:B:T321	1.82	No	Yes	0	9	7
693	B:B:D323	B:B:M325	9.7	No	No	0	7	5
694	B:B:G324	G:G:P49	4.06	No	No	0	9	7
695	B:B:M325	G:G:P49	5.03	No	No	0	5	7
696	B:B:A326	B:B:N340	4.69	No	No	5	7	9
697	B:B:A326	G:G:F61	4.16	No	Yes	5	7	8
698	B:B:T329	B:B:W339	7.28	No	Yes	0	8	9
699	B:B:G330	B:B:L336	3.42	No	Yes	5	5	7
700	B:B:D333	B:B:S331	11.78	Yes	No	12	9	9
701	B:B:D333	B:B:F335	8.36	Yes	No	0	9	4
702	B:B:K337	B:B:W339	8.12	Yes	Yes	12	6	9
703	B:B:I338	G:G:F61	3.77	No	Yes	5	5	8
704	B:B:N340	G:G:F61	13.29	No	Yes	5	9	8
705	G:G:I9	G:G:T6	3.04	No	No	0	2	3
706	G:G:A7	G:G:Q11	3.03	No	No	0	4	3
707	G:G:I9	G:G:R13	11.27	No	No	0	2	6
708	G:G:L15	G:G:L19	2.77	No	Yes	24	2	9
709	G:G:M21	G:G:Q18	9.52	No	Yes	6	1	9
710	G:G:E22	G:G:Q18	12.74	Yes	Yes	6	9	9
711	G:G:E22	G:G:M21	4.06	Yes	No	6	9	1
712	G:G:H44	G:G:Y40	13.07	No	Yes	0	6	6
713	G:G:D48	G:G:L51	10.86	No	Yes	0	9	6
714	G:G:P49	G:G:V54	3.53	No	Yes	0	7	6
715	G:G:P53	G:G:T52	1.75	No	No	0	8	4
716	G:G:P55	G:G:V54	5.3	No	Yes	17	5	6
717	G:G:E58	G:G:V54	5.7	No	Yes	17	5	6
718	G:G:N59	G:G:V54	4.43	No	Yes	0	9	6
719	G:G:P55	G:G:S57	3.56	No	No	17	5	6
720	G:G:E58	G:G:P55	12.58	No	No	17	5	5
721	G:G:E58	G:G:S57	7.19	No	No	17	5	6
722	G:G:N59	G:G:R62	9.64	No	No	0	9	7
723	G:G:F61	G:G:P60	2.89	Yes	No	5	8	9
724	R:R:F10	R:R:F21	7.5	No	Yes	4	7	2
725	R:R:F10	R:R:R270	2.14	No	No	4	7	1
726	R:R:D14	R:R:E12	9.09	No	Yes	0	5	5
727	R:R:E12	R:R:V20	2.85	Yes	No	18	5	2
728	R:R:E12	R:R:N171	5.26	Yes	Yes	18	5	1
729	R:R:E12	R:R:L176	3.98	Yes	Yes	18	5	4
730	R:R:I13	R:R:N17	2.83	No	No	0	3	5
731	R:R:D14	R:R:I169	11.2	No	No	0	5	1
732	R:R:K15	R:R:K165	5.75	No	No	0	3	4
733	R:R:K16	R:R:T185	13.51	No	No	0	4	2
734	R:R:C18	R:R:C183	7.28	No	No	0	9	1
735	R:R:C19	R:R:F21	2.79	No	Yes	4	4	2
736	R:R:C19	R:R:C266	7.28	No	No	4	4	7
737	R:R:N171	R:R:V20	2.96	Yes	No	18	1	2
738	R:R:L176	R:R:V20	4.47	Yes	No	18	4	2
739	R:R:C266	R:R:F21	2.79	No	Yes	4	7	2
740	R:R:F21	R:R:Y269	2.06	Yes	Yes	4	2	2
741	R:R:F21	R:R:R270	14.97	Yes	No	4	2	1
742	R:R:D273	R:R:F21	5.97	No	Yes	0	4	2
743	R:R:N171	R:R:R22	2.41	Yes	No	0	1	3
744	R:R:A174	R:R:R22	4.15	No	No	0	2	3
745	R:R:D23	R:R:R270	19.06	No	No	0	4	1
746	R:R:D24	R:R:V27	2.92	No	No	0	4	3
747	R:R:D24	R:R:R90	3.57	No	No	0	4	4
748	R:R:F25	R:R:K28	7.44	No	No	0	6	3
749	R:R:F25	R:R:V29	5.24	No	No	0	6	5
750	R:R:F25	R:R:L274	12.18	No	No	0	6	1
751	R:R:I26	R:R:L30	4.28	No	Yes	0	5	5
752	R:R:I26	R:R:Y87	6.04	No	Yes	0	5	6
753	R:R:I26	R:R:L274	2.85	No	No	0	5	1
754	R:R:L30	R:R:V29	2.98	Yes	No	0	5	5
755	R:R:I278	R:R:L30	2.85	No	Yes	0	6	5
756	R:R:P31	R:R:P32	7.79	No	No	0	6	5
757	R:R:P31	R:R:V88	3.53	No	No	0	6	3
758	R:R:E37	R:R:V33	2.85	Yes	No	4	7	5
759	R:R:S281	R:R:V33	4.85	No	No	4	6	5
760	R:R:L34	R:R:L80	2.77	No	No	0	8	8
761	R:R:G35	R:R:M84	1.75	No	No	0	5	7
762	R:R:F40	R:R:L36	3.65	No	No	0	6	4
763	R:R:E37	R:R:S281	5.75	Yes	No	4	7	6
764	R:R:E37	R:R:Y284	4.49	Yes	Yes	4	7	7
765	R:R:E37	R:R:M288	4.06	Yes	No	0	7	8
766	R:R:F38	R:R:L42	2.44	Yes	No	29	7	7
767	R:R:F38	R:R:I77	2.51	Yes	No	29	7	6
768	R:R:F38	R:R:L80	2.44	Yes	No	0	7	8
769	R:R:F38	R:R:P81	10.11	Yes	No	0	7	8
770	R:R:F40	R:R:I39	5.02	No	No	0	6	5
771	R:R:G41	R:R:I77	1.76	No	No	0	8	6
772	R:R:G41	R:R:M288	1.75	No	No	0	8	8
773	R:R:I77	R:R:L42	2.85	No	No	29	6	7
774	R:R:G44	R:R:L43	5.13	No	No	0	7	4
775	R:R:G44	R:R:P291	2.03	No	Yes	0	7	9
776	R:R:D73	R:R:N45	14.81	No	No	0	9	9
777	R:R:F74	R:R:N45	2.42	No	No	0	7	9
778	R:R:N45	R:R:P291	8.15	No	Yes	0	9	9
779	R:R:I51	R:R:L47	2.85	No	No	0	7	6
780	R:R:F296	R:R:L47	2.44	No	No	0	8	6
781	R:R:A48	R:R:Y295	2.67	No	Yes	0	9	7
782	R:R:F67	R:R:L49	3.65	No	No	0	6	7
783	R:R:F74	R:R:L49	3.65	No	No	0	7	7
784	R:R:F54	R:R:W50	8.02	No	No	30	4	4
785	R:R:H55	R:R:W50	6.35	No	No	30	5	4
786	R:R:F52	R:R:L56	3.65	Yes	Yes	11	7	5
787	R:R:F52	R:R:R63	4.28	Yes	No	11	7	7
788	R:R:F52	R:R:L66	2.44	Yes	No	11	7	8
789	R:R:F52	R:R:F67	2.14	Yes	No	0	7	6
790	R:R:F52	R:R:Y295	8.25	Yes	Yes	11	7	7
791	R:R:C53	R:R:F54	5.59	No	No	0	4	4
792	R:R:F54	R:R:H55	2.26	No	No	30	4	5
793	R:R:L56	R:R:W59	4.56	Yes	No	0	5	6
794	R:R:L56	R:R:R63	4.86	Yes	No	11	5	7
795	R:R:I64	R:R:W59	2.35	No	No	0	7	6
796	R:R:I139	R:R:S61	7.74	No	No	0	7	6
797	R:R:D124	R:R:S62	5.89	No	No	0	8	8
798	R:R:A144	R:R:I64	3.25	No	No	0	7	7
799	R:R:F65	R:R:V120	7.87	No	No	0	7	7
800	R:R:A144	R:R:F65	2.77	No	No	0	7	7
801	R:R:F65	R:R:S148	2.64	No	No	0	7	8
802	R:R:L66	R:R:V121	2.98	No	No	11	8	9
803	R:R:L66	R:R:Y295	3.52	No	Yes	11	8	7
804	R:R:F117	R:R:N68	13.29	Yes	Yes	16	8	9
805	R:R:N68	R:R:S148	8.94	Yes	No	0	9	8
806	R:R:N68	R:R:W152	5.65	Yes	Yes	16	9	9
807	R:R:L69	R:R:S114	3	Yes	No	0	9	9
808	R:R:F117	R:R:L69	2.44	Yes	Yes	0	8	9
809	R:R:D290	R:R:L69	10.86	Yes	Yes	0	9	9
810	R:R:L69	R:R:Y295	3.52	Yes	Yes	0	9	7
811	R:R:A70	R:R:Y295	4	No	Yes	0	8	7
812	R:R:A72	R:R:W152	2.59	No	Yes	0	8	9
813	R:R:D73	R:R:S287	4.42	No	No	0	9	8
814	R:R:D290	R:R:D73	2.66	Yes	No	0	9	9
815	R:R:L75	R:R:N110	10.98	No	Yes	0	6	9
816	R:R:L107	R:R:L76	4.15	No	No	4	6	7
817	R:R:L76	R:R:N110	5.49	No	Yes	0	7	9
818	R:R:L76	R:R:Y284	4.69	No	Yes	4	7	7
819	R:R:C79	R:R:M103	3.24	No	Yes	0	6	5
820	R:R:C79	R:R:M106	3.24	No	No	0	6	5
821	R:R:C79	R:R:L107	4.76	No	No	0	6	6
822	R:R:L80	R:R:Y284	2.34	No	Yes	0	8	7
823	R:R:F82	R:R:W93	2	No	Yes	13	6	9
824	R:R:F82	R:R:F95	4.29	No	No	13	6	7
825	R:R:L83	R:R:Y87	9.38	No	Yes	0	6	6
826	R:R:L83	R:R:M103	2.83	No	Yes	0	6	5
827	R:R:D85	R:R:F95	3.58	No	No	0	4	7
828	R:R:N86	R:R:W91	9.04	No	No	0	5	4
829	R:R:N86	R:R:W93	2.26	No	Yes	0	5	9
830	R:R:W91	R:R:Y87	9.65	No	Yes	28	4	6
831	R:R:F277	R:R:Y87	3.09	No	Yes	28	5	6
832	R:R:D92	R:R:R89	3.57	No	No	0	4	4
833	R:R:F277	R:R:W91	6.01	No	No	28	5	4
834	R:R:D92	R:R:K94	9.68	No	No	0	4	3
835	R:R:A174	R:R:D92	4.63	No	No	0	2	4
836	R:R:F95	R:R:W93	8.02	No	Yes	13	7	9
837	R:R:C100	R:R:W93	6.53	Yes	Yes	13	9	9
838	R:R:M103	R:R:W93	3.49	Yes	Yes	0	5	9
839	R:R:D97	R:R:R101	4.76	No	No	0	3	6
840	R:R:D97	R:R:K166	5.53	No	No	0	3	4
841	R:R:D97	R:R:P168	14.49	No	No	0	3	4
842	R:R:I98	R:R:P99	3.39	No	No	0	2	5
843	R:R:I98	R:R:R101	2.51	No	No	0	2	6
844	R:R:C100	R:R:M167	3.24	Yes	Yes	13	9	3
845	R:R:C100	R:R:P168	7.53	Yes	No	13	9	4
846	R:R:C100	R:R:C177	7.28	Yes	No	13	9	9
847	R:R:L104	R:R:M103	2.83	No	Yes	0	5	5
848	R:R:L104	R:R:M167	4.24	No	Yes	13	5	3
849	R:R:C177	R:R:L104	4.76	No	No	13	9	5
850	R:R:F105	R:R:M109	3.73	No	Yes	16	6	5
851	R:R:F105	R:R:T159	6.49	No	No	16	6	7
852	R:R:F105	R:R:L163	7.31	No	No	0	6	5
853	R:R:M106	R:R:N110	4.21	No	Yes	0	5	9
854	R:R:L107	R:R:Y284	2.34	No	Yes	4	6	7
855	R:R:M109	R:R:N110	5.61	Yes	Yes	0	5	9
856	R:R:M109	R:R:W152	2.33	Yes	Yes	16	5	9
857	R:R:M109	R:R:T155	3.01	Yes	No	0	5	7
858	R:R:I156	R:R:M109	4.37	No	Yes	0	4	5
859	R:R:M109	R:R:T159	9.03	Yes	No	16	5	7
860	R:R:E196	R:R:R111	4.65	No	No	0	5	8
861	R:R:R111	R:R:T283	2.59	No	Yes	4	8	8
862	R:R:R111	R:R:Y284	2.06	No	Yes	4	8	7
863	R:R:Q112	R:R:T155	4.25	No	No	0	7	7
864	R:R:L158	R:R:Q112	3.99	No	No	0	5	7
865	R:R:M192	R:R:Q112	10.88	No	No	0	5	7
866	R:R:G113	R:R:T155	3.64	No	No	0	7	7
867	R:R:E196	R:R:I115	5.47	No	No	0	5	8
868	R:R:I115	R:R:P200	3.39	No	No	0	8	9
869	R:R:F244	R:R:I115	7.54	Yes	No	0	8	8
870	R:R:I116	R:R:L151	5.71	No	Yes	0	5	7
871	R:R:F117	R:R:L151	7.31	Yes	Yes	0	8	7
872	R:R:F117	R:R:W152	9.02	Yes	Yes	16	8	9
873	R:R:F240	R:R:L118	2.44	Yes	No	0	9	9
874	R:R:L118	R:R:Y294	3.52	No	Yes	0	9	9
875	R:R:P200	R:R:T119	3.5	No	No	0	9	7
876	R:R:I203	R:R:T119	4.56	No	No	0	7	7
877	R:R:R125	R:R:V121	6.54	No	No	11	9	9
878	R:R:V121	R:R:Y294	3.79	No	Yes	11	9	9
879	R:R:F127	R:R:V123	2.62	Yes	No	0	5	6
880	R:R:D124	R:R:R128	4.76	No	Yes	0	8	8
881	R:R:R125	R:R:Y294	4.12	No	Yes	11	9	9
882	R:R:V130	R:R:Y126	13.88	Yes	Yes	9	8	7
883	R:R:H131	R:R:Y126	4.36	No	Yes	9	7	7
884	R:R:F206	R:R:Y126	4.13	No	Yes	9	4	7
885	R:R:C207	R:R:Y126	5.38	No	Yes	0	8	7
886	R:R:R210	R:R:Y126	8.23	Yes	Yes	9	4	7
887	R:R:F127	R:R:H131	3.39	Yes	No	9	5	7
888	R:R:F127	R:R:H134	3.39	Yes	No	9	5	4
889	R:R:F127	R:R:L136	3.65	Yes	No	9	5	4
890	R:R:N137	R:R:R128	9.64	No	Yes	9	4	8
891	R:R:I211	R:R:V129	6.14	No	No	0	8	8
892	R:R:H131	R:R:V130	5.54	No	Yes	9	7	8
893	R:R:R210	R:R:V130	2.62	Yes	Yes	9	4	8
894	R:R:S214	R:R:V130	4.85	No	Yes	0	5	8
895	R:R:H133	R:R:P132	6.1	Yes	No	0	6	8
896	R:R:H134	R:R:L136	2.57	No	No	9	4	4
897	R:R:H134	R:R:N137	5.1	No	No	9	4	4
898	R:R:S140	R:R:T143	3.2	No	No	0	6	3
899	R:R:I147	R:R:L151	2.85	No	Yes	0	5	7
900	R:R:H161	R:R:L162	7.71	No	No	0	7	4
901	R:R:M167	R:R:P168	3.35	Yes	No	13	3	4
902	R:R:I169	R:R:M167	2.92	No	Yes	0	1	3
903	R:R:C177	R:R:M167	4.86	No	Yes	13	9	3
904	R:R:I169	R:R:L176	2.85	No	Yes	0	1	4
905	R:R:N175	R:R:Q170	6.6	No	No	0	4	1
906	R:R:L176	R:R:N171	2.75	Yes	Yes	18	4	1
907	R:R:G172	R:R:G173	2.11	No	No	0	3	4
908	R:R:L176	R:R:S178	3	Yes	No	0	4	4
909	R:R:S178	R:R:S181	3.26	No	No	0	4	4
910	R:R:H189	R:R:S179	8.37	No	No	0	5	4
911	R:R:F180	R:R:H189	7.92	Yes	No	0	3	5
912	R:R:E190	R:R:F180	2.33	Yes	Yes	4	4	3
913	R:R:F180	R:R:F193	2.14	Yes	Yes	4	3	6
914	R:R:F180	R:R:R251	2.14	Yes	Yes	4	3	5
915	R:R:F180	R:R:F276	8.57	Yes	Yes	4	3	4
916	R:R:F180	R:R:L280	3.65	Yes	Yes	4	3	5
917	R:R:I182	R:R:I254	2.94	Yes	No	0	3	4
918	R:R:I182	R:R:L258	4.28	Yes	No	4	3	3
919	R:R:I182	R:R:Y269	6.04	Yes	Yes	4	3	2
920	R:R:D273	R:R:I182	5.6	No	Yes	0	4	3
921	R:R:H184	R:R:T263	4.11	No	No	0	3	3
922	R:R:H184	W:W:?1	8.43	No	Yes	0	3	0
923	R:R:Q187	R:R:T185	4.25	No	No	0	2	2
924	R:R:F186	W:W:?1	7.98	No	Yes	0	4	0
925	R:R:E190	R:R:Q187	2.55	Yes	No	0	4	2
926	R:R:E190	R:R:R251	8.14	Yes	Yes	4	4	5
927	R:R:E190	W:W:?1	13.51	Yes	Yes	4	4	0
928	R:R:A191	W:W:?1	6.88	No	Yes	0	3	0
929	R:R:E196	R:R:F193	7	No	Yes	0	5	6
930	R:R:F193	R:R:R251	3.21	Yes	Yes	4	6	5
931	R:R:F193	R:R:F276	4.29	Yes	Yes	4	6	4
932	R:R:F193	R:R:L280	2.44	Yes	Yes	4	6	5
933	R:R:F255	R:R:L194	2.44	No	Yes	4	5	4
934	R:R:L194	W:W:?1	5.04	Yes	Yes	4	4	0
935	R:R:L195	R:R:L199	2.77	No	No	0	4	4
936	R:R:L195	W:W:?1	4.03	No	Yes	0	4	0
937	R:R:F197	R:R:F198	7.5	Yes	No	0	8	5
938	R:R:F197	R:R:L201	4.87	Yes	Yes	4	8	7
939	R:R:F197	R:R:F240	4.29	Yes	Yes	4	8	9
940	R:R:F197	R:R:F244	4.29	Yes	Yes	4	8	8
941	R:R:F197	R:R:L245	7.31	Yes	No	0	8	6
942	R:R:F198	W:W:?1	3.55	No	Yes	0	5	0
943	R:R:F240	R:R:P200	2.89	Yes	No	0	9	9
944	R:R:L201	R:R:L205	2.77	Yes	No	0	7	4
945	R:R:F240	R:R:L201	2.44	Yes	Yes	4	9	7
946	R:R:F206	R:R:R210	7.48	No	Yes	9	4	4
947	R:R:I233	R:R:S208	3.1	Yes	No	0	7	8
948	R:R:R210	R:R:W213	7	Yes	No	0	4	3
949	R:R:I211	R:R:I233	2.94	No	Yes	0	8	7
950	R:R:I212	R:R:R216	2.51	Yes	No	19	5	4
951	R:R:I212	R:R:I230	7.36	Yes	No	19	5	6
952	R:R:I212	R:R:M234	2.92	Yes	No	0	5	4
953	R:R:Q217	R:R:W213	15.33	No	No	0	5	3
954	R:R:Q217	R:R:S214	2.89	No	No	0	5	5
955	R:R:I226	R:R:L215	7.14	Yes	No	0	6	8
956	R:R:D221	R:R:R216	10.72	No	No	19	3	4
957	R:R:I230	R:R:R216	2.51	No	No	19	6	4
958	R:R:M220	R:R:R218	7.44	Yes	Yes	7	3	5
959	R:R:D221	R:R:K227	4.15	No	No	0	3	4
960	R:R:D221	R:R:I230	4.2	No	No	19	3	6
961	R:R:H223	R:R:K225	5.24	No	No	0	4	5
962	R:R:F232	R:R:R228	7.48	Yes	No	0	7	7
963	R:R:F232	R:R:T231	6.49	Yes	No	0	7	6
964	R:R:F232	R:R:V235	5.24	Yes	No	0	7	5
965	R:R:F232	R:R:S298	3.96	Yes	No	0	7	8
966	R:R:V236	R:R:Y294	7.57	No	Yes	0	8	9
967	R:R:L289	R:R:V239	5.96	No	No	0	7	7
968	R:R:F240	R:R:F244	4.29	Yes	Yes	4	9	8
969	R:R:I242	R:R:V241	3.07	No	No	0	5	5
970	R:R:C243	R:R:M285	3.24	No	No	0	8	5
971	R:R:C243	R:R:N286	9.45	No	No	0	8	9
972	R:R:F244	R:R:T283	3.89	Yes	Yes	4	8	8
973	R:R:F244	R:R:N286	8.46	Yes	No	0	8	9
974	R:R:L245	R:R:P246	3.28	No	No	0	6	9
975	R:R:F282	R:R:P246	5.78	No	No	0	7	9
976	R:R:S247	R:R:T279	3.2	No	No	0	6	7
977	R:R:T279	R:R:V250	3.17	No	No	0	7	5
978	R:R:I254	R:R:R251	2.51	No	Yes	0	4	5
979	R:R:F255	R:R:R251	5.34	No	Yes	4	5	5
980	R:R:F276	R:R:R251	13.9	Yes	Yes	4	4	5
981	R:R:L257	R:R:R253	7.29	Yes	No	0	3	5
982	R:R:I254	R:R:V272	3.07	No	Yes	0	4	4
983	R:R:F255	W:W:?1	15.96	No	Yes	4	5	0
984	R:R:T260	R:R:W256	7.28	No	No	0	1	4
985	R:R:L257	R:R:Y269	2.34	Yes	Yes	4	3	2
986	R:R:L257	R:R:V272	4.47	Yes	Yes	4	3	4
987	R:R:L258	R:R:Y269	7.03	No	Yes	4	3	2
988	R:R:L258	W:W:?1	8.06	No	Yes	4	3	0
989	R:R:S261	R:R:T260	3.2	No	No	0	3	1
990	R:R:G262	R:R:S261	1.86	No	No	0	4	3
991	R:R:E267	R:R:N265	13.15	No	No	0	2	5
992	R:R:V272	R:R:Y269	2.52	Yes	Yes	4	4	2
993	R:R:S271	R:R:V272	3.23	No	Yes	0	3	4
994	R:R:D273	R:R:F277	7.17	No	No	0	4	5
995	R:R:I278	R:R:L274	2.85	No	No	0	6	1
996	R:R:F276	R:R:T279	2.59	Yes	No	0	4	7
997	R:R:F276	R:R:L280	6.09	Yes	Yes	4	4	5
998	R:R:L280	R:R:T283	4.42	Yes	Yes	4	5	8
999	R:R:L280	R:R:Y284	2.34	Yes	Yes	4	5	7
1000	R:R:T283	R:R:Y284	3.75	Yes	Yes	4	8	7
1001	R:R:M285	R:R:M288	4.33	No	No	0	5	8
1002	R:R:L289	R:R:M285	2.83	No	No	0	7	5
1003	R:R:D290	R:R:P291	3.22	Yes	Yes	0	9	9
1004	R:R:D290	R:R:Y294	5.75	Yes	Yes	0	9	9
1005	R:R:P291	R:R:Y295	2.78	Yes	Yes	0	9	7
1006	R:R:Y294	R:R:Y295	1.99	Yes	Yes	11	9	7
1007	R:R:C183	R:R:S181	1.72	No	No	0	1	4
1008	A:A:A7	A:A:S6	1.71	No	No	0	1	7
1009	A:A:G27	B:B:L55	1.71	No	No	0	5	6
1010	A:A:G40	A:A:L39	1.71	No	Yes	0	9	9
1011	A:A:A41	A:A:S44	1.71	No	No	0	7	9
1012	A:A:A41	A:A:S246	1.71	No	No	0	7	9
1013	B:B:G1	B:B:L4	1.71	No	Yes	0	9	4
1014	B:B:C103	B:B:V71	1.71	No	No	0	8	8
1015	B:B:G77	B:B:L95	1.71	No	Yes	0	8	8
1016	R:R:G46	R:R:L49	1.71	No	No	0	4	7
1017	R:R:A144	R:R:S61	1.71	No	No	0	7	6
1018	R:R:G202	R:R:L201	1.71	No	Yes	0	3	7
1019	B:B:A11	G:G:V16	1.7	No	No	0	5	7
1020	B:B:A26	G:G:V30	1.7	No	No	0	3	8
1021	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
1022	B:B:G238	B:B:N239	1.7	No	No	0	7	2
1023	B:B:A257	G:G:V30	1.7	No	No	0	7	8
1024	R:R:A108	R:R:T159	1.68	No	No	0	4	7
1025	A:A:E43	A:A:G42	1.64	No	No	0	9	8
1026	A:A:E216	A:A:G217	1.64	No	No	0	7	5
1027	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
1028	R:R:L30	R:R:P31	1.64	Yes	No	0	5	6
1029	A:A:A220	A:A:I265	1.62	No	Yes	0	8	8
1030	B:B:A140	B:B:I120	1.62	No	No	0	5	6
1031	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
1032	B:B:A257	G:G:I28	1.62	No	No	0	7	4
1033	G:G:A33	G:G:I28	1.62	No	No	0	7	4
1034	R:R:A122	R:R:I204	1.62	No	No	0	9	8
1035	R:R:A237	R:R:I204	1.62	No	No	0	7	8
1036	R:R:A229	R:R:I226	1.62	No	Yes	0	7	6
1037	B:B:S31	B:B:T29	1.6	No	No	0	1	3
1038	B:B:S207	B:B:T223	1.6	No	No	0	5	2
1039	R:R:V235	R:R:V236	1.6	No	No	0	5	8
1040	R:R:V236	R:R:V293	1.6	No	No	0	8	8
1041	R:R:V249	R:R:V250	1.6	No	No	0	6	5
1042	R:R:V292	R:R:V293	1.6	No	No	0	6	8
1043	A:A:T187	A:A:V50	1.59	No	No	0	6	6
1044	A:A:C351	A:A:L353	1.59	No	Yes	0	4	7
1045	R:R:C266	R:R:L11	1.59	No	No	0	7	8
1046	A:A:A245	A:A:L234	1.58	No	No	0	9	8
1047	B:B:A11	G:G:L15	1.58	No	No	24	5	2
1048	B:B:A11	G:G:L19	1.58	No	Yes	24	5	9
1049	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
1050	R:R:A108	R:R:L162	1.58	No	No	0	4	4
1051	R:R:A237	R:R:L205	1.58	No	No	0	7	4
1052	A:A:A12	B:B:N88	1.56	No	Yes	0	4	7
1053	A:A:A226	A:A:N269	1.56	No	No	0	8	9
1054	A:A:C305	A:A:D309	1.56	No	No	0	3	4
1055	G:G:I9	G:G:S8	1.55	No	No	0	2	4
1056	A:A:I49	A:A:V50	1.54	Yes	No	0	7	6
1057	B:B:A28	B:B:D27	1.54	No	No	0	4	8
1058	B:B:A56	B:B:D76	1.54	No	No	0	7	9
1059	B:B:A193	B:B:D195	1.54	No	No	0	4	5
1060	R:R:I156	R:R:V160	1.54	No	No	0	4	4
1061	B:B:M262	B:B:S31	1.53	Yes	No	0	4	1
1062	A:A:K54	A:A:V50	1.52	No	No	0	7	6
1063	B:B:A56	B:B:Q75	1.52	No	Yes	0	7	9
1064	R:R:K28	R:R:V27	1.52	No	No	0	3	3
1065	R:R:M84	R:R:V88	1.52	No	No	0	7	3
1066	R:R:F40	R:R:G41	1.51	No	No	0	6	8
1067	A:A:G352	R:R:R63	1.5	No	No	0	8	7
1068	R:R:L56	R:R:S58	1.5	Yes	No	0	5	6
1069	A:A:L5	A:A:V13	1.49	No	No	0	2	3
1070	B:B:V327	G:G:L50	1.49	No	No	0	6	9
1071	R:R:L194	R:R:V248	1.49	Yes	No	0	4	8
1072	R:R:L201	R:R:V241	1.49	Yes	No	0	7	5
1073	R:R:L257	R:R:V268	1.49	Yes	No	0	3	1
1074	A:A:N241	A:A:V233	1.48	No	No	0	9	5
1075	R:R:N68	R:R:V71	1.48	Yes	No	0	9	6
1076	R:R:I212	R:R:I233	1.47	Yes	Yes	0	5	7
1077	R:R:I238	R:R:I242	1.47	No	No	0	5	5
1078	A:A:D200	A:A:V185	1.46	No	No	0	9	5
1079	B:B:N132	B:B:T128	1.46	No	Yes	0	3	3
1080	G:G:A43	G:G:H44	1.46	No	No	0	4	6
1081	A:A:I55	A:A:K54	1.45	No	No	0	8	7
1082	A:A:I278	A:A:K279	1.45	Yes	No	0	6	2
1083	A:A:D328	A:A:T329	1.45	No	No	0	9	9
1084	B:B:D322	B:B:T65	1.45	No	No	0	1	1
1085	A:A:E8	A:A:S6	1.44	No	No	0	5	7
1086	B:B:E3	B:B:S2	1.44	No	No	0	5	5
1087	B:B:Q75	B:B:S98	1.44	Yes	No	0	9	8
1088	G:G:Q11	G:G:S8	1.44	No	No	0	3	4
1089	R:R:K15	R:R:K16	1.44	No	No	0	3	4
1090	R:R:I13	R:R:L11	1.43	No	No	0	3	8
1091	R:R:I98	R:R:L102	1.43	No	No	0	2	5
1092	R:R:I146	R:R:L150	1.43	No	No	0	3	4
1093	R:R:I154	R:R:L151	1.43	No	Yes	0	5	7
1094	R:R:I154	R:R:L158	1.43	No	No	0	5	5
1095	R:R:I252	R:R:L194	1.43	No	Yes	0	6	4
1096	R:R:E267	R:R:V268	1.43	No	No	0	2	1
1097	R:R:I64	R:R:N141	1.42	No	No	0	7	2
1098	A:A:K51	A:A:N47	1.4	No	No	0	9	9
1099	A:A:K314	A:A:N311	1.4	No	Yes	0	3	8
1100	B:B:K301	B:B:N35	1.4	Yes	No	0	5	1
1101	A:A:P288	A:A:Y287	1.39	No	Yes	0	5	7
1102	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
1103	A:A:R32	R:R:A135	1.38	No	No	0	4	5
1104	G:G:A10	G:G:R13	1.38	No	No	0	2	6
1105	G:G:D36	G:G:K32	1.38	No	No	0	5	5
1106	R:R:A145	R:R:R142	1.38	No	No	0	3	4
1107	A:A:E207	A:A:K209	1.35	No	No	0	9	8
1108	A:A:E276	A:A:K279	1.35	No	No	0	5	2
1109	B:B:L7	B:B:Q6	1.33	No	No	0	8	1
1110	B:B:E10	B:B:L7	1.33	No	No	0	8	8
1111	A:A:R208	A:A:S252	1.32	Yes	No	0	9	7
1112	B:B:N16	B:B:Q13	1.32	No	No	0	1	1
1113	R:R:F232	R:R:S297	1.32	Yes	No	0	7	6
1114	A:A:H195	A:A:K197	1.31	No	Yes	0	4	6
1115	R:R:F296	R:R:V292	1.31	No	No	0	8	6
1116	A:A:D237	A:A:E238	1.3	No	No	0	8	4
1117	A:A:D237	A:A:E239	1.3	No	No	0	8	4
1118	R:R:A191	R:R:W188	1.3	No	No	0	3	5
1119	B:B:D267	B:B:H266	1.26	No	Yes	0	3	4
1120	R:R:F74	R:R:I78	1.26	No	No	0	7	6
1121	R:R:N175	R:R:W93	1.13	No	Yes	0	4	9
1122	R:R:H259	R:R:W256	1.06	No	No	0	1	4
1123	R:R:R253	R:R:W256	1	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:V34	5.24	5	7	5
2	A:A:L39	4.4575	4	3	9
3	A:A:K46	4.064	5	21	9
4	A:A:I49	4.1875	4	10	7
5	A:A:L194	5.1425	4	7	4
6	A:A:F196	7.298	5	7	7
7	A:A:K197	5.6725	4	1	6
8	A:A:F199	6.544	5	1	5
9	A:A:R208	3.805	4	0	9
10	A:A:K210	5.795	6	1	9
11	A:A:W211	4.345	6	1	9
12	A:A:H213	5.25	4	1	8
13	A:A:C214	2.85	4	1	7
14	A:A:F215	4.52125	8	1	9
15	A:A:F223	4.875	6	3	9
16	A:A:V225	4.58	4	3	7
17	A:A:Y230	6.90167	6	3	8
18	A:A:R242	8.6825	4	3	9
19	A:A:H244	6.96	4	22	4
20	A:A:F250	4.965	6	3	9
21	A:A:C254	3.8525	4	3	5
22	A:A:W258	8.026	5	1	5
23	A:A:F259	6.6525	4	3	9
24	A:A:I265	2.4725	4	10	8
25	A:A:L266	4.3425	4	3	9
26	A:A:F267	4.41125	8	10	9
27	A:A:L268	4.52	5	3	8
28	A:A:F274	4.415	6	3	9
29	A:A:I278	3.585	4	3	6
30	A:A:S281	4.14	4	3	7
31	A:A:L283	3.91	5	3	7
32	A:A:Y287	3.75667	6	0	7
33	A:A:Y290	9.1075	4	0	7
34	A:A:F307	4.048	5	3	8
35	A:A:N311	3.398	5	3	8
36	A:A:R313	4.64	4	3	4
37	A:A:K317	3.835	4	3	7
38	A:A:T321	7.1925	4	3	5
39	A:A:H322	5.684	5	10	9
40	A:A:F323	4.944	5	3	4
41	A:A:T324	5.16	5	10	9
42	A:A:N331	6.74333	6	10	8
43	A:A:F334	4.7875	4	10	3
44	A:A:F336	5.455	6	7	8
45	A:A:T340	4.614	5	7	6
46	A:A:I344	4.4275	4	7	6
47	A:A:L353	3.97	4	0	7
48	A:A:F354	7.415	4	23	5
49	B:B:L4	3.98	4	0	4
50	B:B:L14	4.815	4	0	8
51	B:B:R22	7.6825	4	25	6
52	B:B:T34	4.8375	4	2	5
53	B:B:V40	2.77	4	0	3
54	B:B:L51	7.89	4	5	9
55	B:B:H54	8.438	5	0	9
56	B:B:Y59	5.9725	4	1	8
57	B:B:M61	3.2325	4	5	6
58	B:B:W63	5.30833	6	5	7
59	B:B:Q75	4.784	5	1	9
60	B:B:I81	4.2625	4	8	7
61	B:B:W82	8.87833	6	5	9
62	B:B:N88	4.356	5	20	7
63	B:B:K89	8.9575	4	0	9
64	B:B:I93	4.335	4	8	7
65	B:B:L95	3.615	4	8	8
66	B:B:W99	6.23833	6	1	9
67	B:B:Y105	3.81	7	8	6
68	B:B:Y111	6.252	5	0	4
69	B:B:C114	4.64	4	8	8
70	B:B:L117	3.8725	4	1	9
71	B:B:Y124	3.72167	6	8	6
72	B:B:L126	4.185	4	8	5
73	B:B:T128	3.1375	4	27	3
74	B:B:H142	6.66143	7	1	9
75	B:B:Y145	4.53778	9	1	8
76	B:B:C149	2.205	4	1	8
77	B:B:F151	3.87	7	1	9
78	B:B:T159	5.1	4	1	9
79	B:B:G162	4.1025	4	1	9
80	B:B:D163	8.75	4	1	9
81	B:B:W169	8.82	6	1	8
82	B:B:Q176	7.2575	4	1	4
83	B:B:T178	3.9675	4	6	4
84	B:B:F180	7.346	5	6	7
85	B:B:H183	6.53333	6	6	9
86	B:B:D186	4.366	5	1	9
87	B:B:L190	3.69	4	0	5
88	B:B:F199	6.77	4	6	9
89	B:B:V200	5.31	5	2	6
90	B:B:C204	5.54	4	1	7
91	B:B:D205	5.265	4	6	9
92	B:B:K209	7.018	5	6	6
93	B:B:L210	3.735	4	0	5
94	B:B:W211	8.66167	6	6	8
95	B:B:D212	6.9025	4	6	9
96	B:B:E215	9.2475	4	6	3
97	B:B:C218	4.445	4	6	5
98	B:B:Q220	5.3825	4	0	7
99	B:B:F222	7.03	4	2	8
100	B:B:H225	8.37857	7	2	9
101	B:B:I232	4.082	5	2	8
102	B:B:F235	5.53143	7	15	6
103	B:B:P236	5.3075	4	15	7
104	B:B:F241	6.13571	7	2	6
105	B:B:T243	4.18667	6	2	8
106	B:B:G244	2.2875	4	2	5
107	B:B:D247	6.16	5	2	9
108	B:B:T249	5.88	4	2	6
109	B:B:C250	2.8425	4	2	8
110	B:B:R251	10.328	5	2	8
111	B:B:F253	6	6	2	6
112	B:B:M262	4.7975	4	2	4
113	B:B:Y264	3.94	5	2	5
114	B:B:H266	3.345	4	0	4
115	B:B:I269	2.865	4	2	4
116	B:B:I273	4.3625	4	2	6
117	B:B:F278	4.24	4	15	7
118	B:B:L285	2.9425	4	0	6
119	B:B:Y289	5.51	6	2	7
120	B:B:N293	4.895	4	0	5
121	B:B:N295	8.3275	4	2	6
122	B:B:W297	3.73833	6	2	8
123	B:B:K301	4.37	4	26	5
124	B:B:R304	6.7325	4	2	5
125	B:B:H311	7.54	5	12	9
126	B:B:L318	3.254	5	0	6
127	B:B:T321	5.83	4	5	7
128	B:B:W332	10.9783	6	1	9
129	B:B:D333	8.2375	4	12	9
130	B:B:L336	3.93	6	5	7
131	B:B:K337	6.015	4	12	6
132	B:B:W339	9.542	5	12	9
133	G:G:Q18	7.6875	4	6	9
134	G:G:L19	2.83	4	24	9
135	G:G:E22	6.725	4	6	9
136	G:G:Y40	8.7975	4	15	6
137	G:G:L51	6.3475	4	0	6
138	G:G:V54	4.74	4	17	6
139	G:G:F61	5.44875	8	5	8
140	R:R:E12	5.295	4	18	5
141	R:R:F21	6.01333	6	4	2
142	R:R:L30	2.9375	4	0	5
143	R:R:E37	4.2875	4	4	7
144	R:R:F38	4.375	4	29	7
145	R:R:F52	4.152	5	11	7
146	R:R:L56	3.6425	4	11	5
147	R:R:N68	7.34	4	16	9
148	R:R:L69	4.955	4	0	9
149	R:R:Y87	7.04	4	28	6
150	R:R:W93	3.905	6	13	9
151	R:R:C100	6.145	4	13	9
152	R:R:M103	3.0975	4	0	5
153	R:R:M109	4.68	6	16	5
154	R:R:N110	6.5725	4	0	9
155	R:R:F117	8.015	4	16	8
156	R:R:Y126	7.196	5	9	7
157	R:R:F127	3.2625	4	9	5
158	R:R:R128	5.3975	4	9	8
159	R:R:V130	6.7225	4	9	8
160	R:R:H133	6.1675	4	0	6
161	R:R:L151	4.325	4	0	7
162	R:R:W152	4.8975	4	16	9
163	R:R:M167	3.722	5	13	3
164	R:R:N171	3.345	4	18	1
165	R:R:L176	3.41	5	18	4
166	R:R:F180	4.45833	6	4	3
167	R:R:I182	4.715	4	4	3
168	R:R:E190	6.6325	4	4	4
169	R:R:F193	3.816	5	4	6
170	R:R:L194	2.6	4	4	4
171	R:R:F197	5.652	5	4	8
172	R:R:L201	2.656	5	4	7
173	R:R:R210	6.3325	4	9	4
174	R:R:I212	3.565	4	19	5
175	R:R:R218	4.985	4	7	5
176	R:R:M220	6.1425	4	7	3
177	R:R:I226	4.4725	4	23	6
178	R:R:F232	4.898	5	0	7
179	R:R:I233	2.59	4	0	7
180	R:R:F240	3.27	5	4	9
181	R:R:F244	5.694	5	4	8
182	R:R:R251	5.87333	6	4	5
183	R:R:L257	3.8975	4	4	3
184	R:R:Y269	3.998	5	4	2
185	R:R:V272	3.3225	4	4	4
186	R:R:F276	7.088	5	4	4
187	R:R:L280	3.788	5	4	5
188	R:R:T283	3.6625	4	4	8
189	R:R:Y284	3.14429	7	4	7
190	R:R:D290	5.6225	4	0	9
191	R:R:P291	4.045	4	0	9
192	R:R:Y294	4.45667	6	11	9
193	R:R:Y295	3.81857	7	11	7
194	W:W:?1	8.16	9	4	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:S316	B:B:W332	18.6281	3.71	No	Yes	0	9	9
2	B:B:C317	B:B:S316	18.4137	3.44	No	No	0	7	9
3	B:B:C317	B:B:M61	12.0119	4.86	No	Yes	0	7	6
4	A:A:C214	A:A:F215	53.0234	2.79	Yes	Yes	1	7	9
5	A:A:C214	A:A:H213	54.9703	2.95	Yes	Yes	1	7	8
6	A:A:H213	B:B:W332	72.4679	4.23	Yes	Yes	1	8	9
7	A:A:F215	A:A:L37	90.3324	7.31	Yes	No	0	9	9
8	A:A:L37	A:A:L39	90.4191	5.54	No	Yes	0	9	9
9	A:A:G40	A:A:L39	99.9436	1.71	No	Yes	0	9	9
10	A:A:G40	A:A:K46	100	6.97	No	Yes	0	9	9
11	A:A:K46	A:A:L38	52.2932	4.23	Yes	No	21	9	8
12	A:A:I222	A:A:L38	52.321	2.85	No	No	0	7	8
13	A:A:H213	A:A:W258	17.9951	11.64	Yes	Yes	1	8	5
14	A:A:I212	A:A:W258	18.714	2.35	No	Yes	0	8	5
15	A:A:F223	A:A:L39	27.495	4.87	Yes	Yes	3	9	9
16	A:A:F223	A:A:L249	15.5878	6.09	Yes	No	0	9	9
17	A:A:L249	A:A:R208	15.5562	3.64	No	Yes	0	9	9
18	A:A:F274	A:A:Y230	13.0299	5.16	Yes	Yes	3	9	8
19	A:A:F223	A:A:V225	25.9774	2.62	Yes	Yes	3	9	7
20	A:A:F274	A:A:I303	14.6304	2.51	Yes	No	0	9	7
21	A:A:F307	A:A:I303	21.6327	2.51	Yes	No	0	8	7
22	A:A:F307	A:A:V225	15.8535	7.87	Yes	Yes	3	8	7
23	A:A:F307	A:A:L266	16.0394	2.44	Yes	Yes	3	8	9
24	A:A:F223	A:A:L266	16.901	2.44	Yes	Yes	3	9	9
25	A:A:F267	A:A:I222	45.4305	2.51	Yes	No	0	9	7
26	A:A:C224	A:A:K46	47.4342	3.23	No	Yes	0	7	9
27	A:A:C224	A:A:I49	47.3595	3.27	No	Yes	0	7	7
28	A:A:F267	A:A:I49	45.1272	6.28	Yes	Yes	10	9	7
29	A:A:W211	B:B:Y145	22.3642	3.86	Yes	Yes	1	9	8
30	A:A:F215	A:A:W211	29.0513	2	Yes	Yes	1	9	9
31	B:B:L117	B:B:W99	16.2386	5.69	Yes	Yes	1	9	9
32	B:B:M101	B:B:Y145	13.182	3.59	No	Yes	1	9	8
33	B:B:G116	B:B:M101	37.863	3.49	No	No	0	9	9
34	B:B:G115	B:B:G116	37.4786	2.11	No	No	0	9	9
35	B:B:C114	B:B:G115	35.0346	3.92	Yes	No	0	8	9
36	B:B:C114	B:B:L95	31.1599	4.76	Yes	Yes	8	8	8
37	B:B:L95	B:B:Y124	30.6275	3.52	Yes	Yes	8	8	6
38	B:B:V112	B:B:Y124	26.5804	3.79	No	Yes	8	8	6
39	B:B:V112	B:B:Y105	24.6455	2.52	No	Yes	8	8	6
40	A:A:F267	A:A:F334	87.3247	2.14	Yes	Yes	10	9	3
41	R:R:H223	R:R:K225	92.4038	5.24	No	No	0	4	5
42	A:A:E318	R:R:H223	92.6241	3.69	No	No	0	4	4
43	A:A:E318	A:A:Y320	87.7319	8.98	No	No	0	4	7
44	A:A:F334	A:A:Y320	87.8025	2.06	Yes	No	0	3	7
45	A:A:F354	R:R:K225	91.9625	6.2	Yes	No	0	5	5
46	A:A:F354	A:A:L348	90.7404	9.74	Yes	No	23	5	9
47	A:A:L348	A:A:L353	90.6335	4.15	No	Yes	0	9	7
48	A:A:L353	R:R:R125	87.5014	7.29	Yes	No	0	7	9
49	B:B:H62	B:B:Y105	29.7379	4.36	No	Yes	0	6	6
50	B:B:H62	B:B:R150	29.5138	12.41	No	No	0	6	6
51	B:B:L190	B:B:R150	18.4445	2.43	Yes	No	0	5	6
52	B:B:F199	B:B:V158	18.2152	3.93	Yes	No	0	9	5
53	B:B:L210	B:B:R219	12.4929	2.43	Yes	No	0	5	5
54	B:B:D258	B:B:Q220	13.2974	5.22	No	Yes	0	7	7
55	B:B:D258	B:B:R22	11.7656	20.25	No	Yes	25	7	6
56	B:B:I18	B:B:R22	10.2419	2.51	No	Yes	0	7	6
57	B:B:L192	B:B:R150	10.8763	2.43	No	No	0	5	6
58	B:B:R314	B:B:W332	60.8402	20.99	No	Yes	0	8	9
59	B:B:D290	B:B:R314	50.7897	13.1	No	No	0	6	8
60	B:B:D290	B:B:G272	46.5023	3.35	No	No	2	6	4
61	B:B:G272	B:B:I273	46.3707	1.76	No	Yes	2	4	6
62	B:B:G244	B:B:I273	37.832	3.53	Yes	Yes	2	5	6
63	B:B:G244	B:B:T243	37.6826	1.82	Yes	Yes	2	5	8
64	B:B:I232	B:B:T243	13.4796	3.04	Yes	Yes	2	8	8
65	B:B:F241	B:B:T243	15.6589	2.59	Yes	Yes	2	6	8
66	B:B:F241	B:B:V200	10.2179	6.55	Yes	Yes	2	6	6
67	B:B:L210	B:B:V200	13.5966	2.98	Yes	Yes	0	5	6
68	B:B:A193	B:B:F234	12.0096	2.77	No	No	0	4	5
69	B:B:R314	B:B:T274	11.4847	2.59	No	No	0	8	8
70	R:R:R125	R:R:Y294	83.0825	4.12	No	Yes	11	9	9
71	R:R:L118	R:R:Y294	54.1581	3.52	No	Yes	0	9	9
72	R:R:F240	R:R:L118	53.9059	2.44	Yes	No	0	9	9
73	R:R:F197	R:R:F240	19.3255	4.29	Yes	Yes	4	8	9
74	R:R:F197	R:R:F198	18.3861	7.5	Yes	No	0	8	5
75	R:R:F198	W:W:?1	18.1142	3.55	No	Yes	0	5	0
76	R:R:L258	W:W:?1	12.3173	8.06	No	Yes	4	3	0
77	R:R:F240	R:R:F244	29.8967	4.29	Yes	Yes	4	9	8
78	R:R:F244	R:R:T283	25.8128	3.89	Yes	Yes	4	8	8
79	R:R:T283	R:R:Y284	20.958	3.75	Yes	Yes	4	8	7
80	R:R:L107	R:R:Y284	16.9124	2.34	No	Yes	4	6	7
81	R:R:C79	R:R:L107	16.6448	4.76	No	No	0	6	6
82	R:R:C79	R:R:M103	16.8735	3.24	No	Yes	0	6	5
83	R:R:D290	R:R:Y294	12.1141	5.75	Yes	Yes	0	9	9
84	R:R:Y294	R:R:Y295	15.1506	1.99	Yes	Yes	11	9	7
85	R:R:F117	R:R:L69	16.8242	2.44	Yes	Yes	0	8	9
86	B:B:L117	B:B:M101	25.0734	2.83	Yes	No	1	9	9
87	A:A:W211	B:B:L117	12.9605	2.28	Yes	Yes	1	9	9
88	A:A:F215	B:B:W99	11.5932	12.03	Yes	Yes	1	9	9
89	B:B:F222	B:B:Q220	12.3084	8.2	Yes	Yes	0	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:E190	R:R:F180	2.33	4	Yes	Yes	4	3	1	2
R:R:F180	R:R:R251	2.14	4	Yes	Yes	3	5	2	2
R:R:I182	R:R:L258	4.28	4	Yes	No	3	3	2	1
R:R:I182	R:R:Y269	6.04	4	Yes	Yes	3	2	2	2
R:R:H184	R:R:T263	4.11	0	No	No	3	3	1	2
R:R:H184	W:W:?1	8.43	0	No	Yes	3	0	1	0
R:R:F186	W:W:?1	7.98	0	No	Yes	4	0	1	0
R:R:E190	R:R:Q187	2.55	4	Yes	No	4	2	1	2
R:R:E190	R:R:R251	8.14	4	Yes	Yes	4	5	1	2
R:R:E190	W:W:?1	13.51	4	Yes	Yes	4	0	1	0
R:R:A191	W:W:?1	6.88	0	No	Yes	3	0	1	0
R:R:F255	R:R:L194	2.44	4	No	Yes	5	4	1	1
R:R:L194	W:W:?1	5.04	4	Yes	Yes	4	0	1	0
R:R:L195	R:R:L199	2.77	0	No	No	4	4	1	2
R:R:L195	W:W:?1	4.03	0	No	Yes	4	0	1	0
R:R:F197	R:R:F198	7.5	4	Yes	No	8	5	2	1
R:R:F198	W:W:?1	3.55	0	No	Yes	5	0	1	0
R:R:F255	R:R:R251	5.34	4	No	Yes	5	5	1	2
R:R:F255	W:W:?1	15.96	4	No	Yes	5	0	1	0
R:R:L258	R:R:Y269	7.03	4	No	Yes	3	2	1	2
R:R:L258	W:W:?1	8.06	4	No	Yes	3	0	1	0
R:R:L194	R:R:V248	1.49	4	Yes	No	4	8	1	2
R:R:I252	R:R:L194	1.43	0	No	Yes	6	4	2	1
R:R:A191	R:R:W188	1.3	0	No	No	3	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
100.00	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
87.50	Single	8J6Q	Compound 9n	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
25.00	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
22.22	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
21.05	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
21.05	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
20.00	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
20.00	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
17.65	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
17.65	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
17.39	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
16.67	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
16.67	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
16.67	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
16.67	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
16.67	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
15.79	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/β1/γ2
15.79	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
15.79	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
15.38	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
15.38	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
15.38	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
15.38	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
14.29	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
14.29	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
14.29	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
14.29	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
14.29	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
14.29	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
14.29	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
14.29	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
14.29	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
14.29	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
13.64	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
13.64	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.64	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
13.33	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
13.33	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
13.33	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
13.33	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
13.33	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
13.33	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
13.33	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
13.33	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
13.33	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
13.33	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
13.04	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
12.50	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
12.50	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
12.50	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
12.50	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
12.50	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
12.50	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
12.50	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
12.50	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
12.12	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
12.00	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
11.76	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
11.76	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
11.76	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
11.76	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
11.76	Single	8TH3	AT118-H Nanobody	8TH3-AT₁-AT118-H Nanobody
11.76	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
11.76	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
11.76	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
11.54	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
11.54	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
11.54	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
11.11	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
11.11	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
11.11	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
11.11	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.11	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
11.11	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
11.11	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
11.11	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
11.11	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
11.11	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
10.71	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
10.71	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
10.71	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
10.53	Single	5V56	TC114	5V56-SMO-TC114
10.53	Single	5V57	TC114	5V57-SMO-TC114
10.53	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
10.53	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
10.53	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
10.53	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
10.53	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
10.53	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
10.53	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
10.53	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
10.53	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
10.53	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
10.34	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
10.34	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
10.34	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
10.00	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
10.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
10.00	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
10.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
10.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
10.00	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
10.00	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
10.00	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
10.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
10.00	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
10.00	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
10.00	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
10.00	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
10.00	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
10.00	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
10.00	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
10.00	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
10.00	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
10.00	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
10.00	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116-Cholesterol
10.00	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
10.00	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
10.00	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
10.00	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
9.68	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
9.68	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
9.68	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
9.52	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
9.52	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
9.52	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
9.52	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
9.52	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
9.52	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
9.52	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
9.52	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
9.52	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
9.52	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
9.52	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
9.52	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
9.52	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
9.38	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
9.09	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
9.09	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/β1/γ2
9.09	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
9.09	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
9.09	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
9.09	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
9.09	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
9.09	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
8.70	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
8.70	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
8.70	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
8.70	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
8.70	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
8.70	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
8.70	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
8.70	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
8.70	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
8.70	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.70	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
8.70	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
8.70	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
8.70	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
8.70	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
8.70	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
8.70	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.70	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
8.70	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
8.33	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
8.33	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
8.33	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
8.33	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
8.33	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
8.33	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
8.33	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
8.33	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
8.33	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
8.33	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
8.33	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
8.33	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
8.33	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
8.33	Single	9GE2	Cholesterol	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
8.33	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
8.33	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
8.11	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
8.00	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
8.00	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
8.00	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
8.00	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
8.00	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
8.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
8.00	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
8.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.00	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
8.00	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
7.89	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
7.69	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
7.69	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
7.69	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
7.69	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
7.69	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
7.69	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
7.69	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
7.69	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
7.69	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.69	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
7.69	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
7.69	Single	7Y14	Beta-Alanine	7Y14-MRGPRD-β-Alanine
7.69	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
7.69	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/β1/γ2
7.69	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
7.69	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
7.69	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
7.69	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
7.69	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
7.69	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
7.69	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
7.69	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
7.69	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
7.69	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
7.69	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
7.41	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
7.41	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
7.41	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
7.41	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
7.41	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
7.41	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
7.41	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.41	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
7.41	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
7.41	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
7.41	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.41	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
7.41	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
7.41	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
7.41	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
7.41	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
7.41	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
7.41	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
7.14	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
7.14	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
7.14	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
7.14	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
7.14	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
7.14	Single	6OBA	GTPL11074	6OBA-β₂-S-Alprenolol-GTPL11074
7.14	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
7.14	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
7.14	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
7.14	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
7.14	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
7.14	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
7.14	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
7.14	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
7.14	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
7.14	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
7.14	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
7.14	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
7.14	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7Y12	Beta-Alanine	7Y12-MRGPRD-β-Alanine-Gi1/β1/γ2
7.14	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
7.14	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
7.14	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
7.14	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
7.14	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8WG8	Peptide	8WG8-Glucagon-Peptide-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
7.14	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
7.14	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
7.14	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
7.14	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
7.14	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
7.14	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
7.14	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
7.14	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
6.90	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
6.90	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
6.90	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
6.90	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
6.90	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
6.90	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
6.90	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.90	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
6.90	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
6.90	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
6.90	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
6.90	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
6.90	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
6.90	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
6.90	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
6.90	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
6.67	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
6.67	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
6.67	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
6.67	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
6.67	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
6.67	Single	6LI0	C17	6LI0-GPR52-C17
6.67	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
6.67	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
6.67	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
6.67	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
6.67	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
6.67	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
6.67	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
6.67	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
6.67	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.67	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
6.67	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
6.67	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
6.67	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
6.67	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
6.67	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
6.67	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
6.67	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
6.67	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
6.67	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
6.67	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
6.67	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
6.67	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
6.67	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
6.67	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
6.67	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
6.67	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
6.67	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
6.67	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
6.67	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
6.67	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
6.67	Single	8K9L	VV9	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
6.67	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
6.67	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
6.67	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
6.67	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
6.67	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
6.67	Single	9B9Y	7DY	9B9Y-CB₁-7DY
6.67	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
6.67	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
6.67	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
6.67	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
6.67	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
6.67	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
6.67	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
6.67	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
6.67	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
6.67	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
6.67	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
6.67	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
6.67	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
6.67	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
6.45	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
6.45	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
6.45	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
6.45	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
6.45	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
6.45	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
6.45	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
6.45	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
6.45	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
6.45	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
6.25	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
6.25	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
6.25	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
6.25	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
6.25	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
6.25	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
6.25	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
6.25	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
6.25	Single	5U09	Taranabant	5U09-CB₁-Taranabant
6.25	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
6.25	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
6.25	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
6.25	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
6.25	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
6.25	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
6.25	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
6.25	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
6.25	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
6.25	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
6.25	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
6.25	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
6.25	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
6.25	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
6.25	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
6.25	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
6.25	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
6.25	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
6.25	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
6.25	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
6.25	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
6.25	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
6.25	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
6.25	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
6.25	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
6.25	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
6.25	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
6.25	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
6.25	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
6.25	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
6.25	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
6.25	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
6.25	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
6.25	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
6.25	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
6.25	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
6.25	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
6.25	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
6.25	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
6.25	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
6.25	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ
6.25	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
6.25	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
6.25	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
6.25	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
6.25	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
6.25	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
6.25	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
6.25	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
6.25	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
6.25	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
6.25	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
6.25	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
6.06	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
6.06	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
6.06	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
6.06	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
6.06	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
6.06	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
5.88	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
5.88	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
5.88	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
5.88	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
5.88	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
5.88	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
5.88	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
5.88	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
5.88	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
5.88	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
5.88	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
5.88	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
5.88	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
5.88	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
5.88	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
5.88	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
5.88	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
5.88	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
5.88	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
5.88	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
5.88	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
5.88	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
5.88	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
5.88	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
5.88	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
5.88	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
5.88	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
5.88	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.88	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.88	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
5.88	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
5.88	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
5.88	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
5.88	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
5.88	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
5.88	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
5.88	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.88	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
5.88	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.88	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
5.88	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
5.88	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
5.88	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
5.88	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
5.88	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
5.88	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
5.88	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
5.88	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
5.88	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
5.88	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
5.88	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
5.88	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
5.88	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
5.88	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
5.88	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
5.88	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
5.88	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
5.88	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
5.88	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
5.88	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100-Cholesterol
5.88	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
5.88	Consensus	a2_off	Orthosteric Ligand	a2a_off
5.88	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
5.88	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
5.88	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
5.88	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
5.88	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.88	Consensus	hca_on	Orthosteric Ligand	hca2_on
5.88	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
5.88	Consensus	sensory_off	Orthosteric Ligand	opsins_off
5.56	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
5.56	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
5.56	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
5.56	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
5.56	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
5.56	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
5.56	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
5.56	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
5.56	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
5.56	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
5.56	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
5.56	Single	5UEN	DU172	5UEN-A₁-DU172
5.56	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
5.56	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
5.56	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
5.56	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
5.56	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
5.56	Single	6IIV	Daltroban	6IIV-TP-Daltroban
5.56	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
5.56	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
5.56	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
5.56	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
5.56	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
5.56	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
5.56	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
5.56	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
5.56	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
5.56	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
5.56	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.56	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
5.56	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
5.56	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
5.56	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
5.56	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
5.56	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
5.56	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
5.56	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
5.56	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
5.56	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
5.56	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
5.56	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
5.56	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
5.56	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
5.56	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.56	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
5.56	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.56	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.56	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
5.56	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
5.56	Single	8T1W	CVN424	8T1W-GPR6-CVN424
5.56	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
5.56	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
5.56	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
5.56	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
5.56	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
5.56	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
5.56	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
5.56	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
5.56	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
5.56	Single	9IMA	Talquetamab	9IMA-GPRC5D-Talquetamab
5.56	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
5.56	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.56	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.56	Consensus	a3_on	Orthosteric Ligand	a3a_on
5.56	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
5.56	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
5.56	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
5.56	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
5.56	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.56	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
5.56	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
5.56	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
5.56	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.56	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
5.56	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
5.26	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
5.26	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
5.26	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
5.26	Single	5N2S	PSB36	5N2S-A₁-PSB36
5.26	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
5.26	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
5.26	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
5.26	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
5.26	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
5.26	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
5.26	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
5.26	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
5.26	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
5.26	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
5.26	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
5.26	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
5.26	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
5.26	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
5.26	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
5.26	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
5.26	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.26	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.26	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
5.26	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
5.26	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
5.26	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
5.26	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
5.26	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
5.26	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
5.26	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/β1/γ2
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
5.26	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
5.26	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
5.26	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
5.26	Single	7W41	PD176252	7W41-BB₂-PD176252
5.26	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
5.26	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
5.26	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
5.26	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
5.26	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
5.26	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
5.26	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
5.26	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
5.26	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
5.26	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
5.26	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
5.26	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
5.26	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
5.26	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.26	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
5.26	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
5.26	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
5.26	Single	8WGB	W9R	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
5.26	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
5.26	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
5.26	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
5.26	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.26	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.26	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
5.26	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
5.26	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
5.26	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.26	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.26	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.26	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
5.26	Consensus	dp_off	Orthosteric Ligand	dp2_off
5.26	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
5.26	Consensus	ep_off	Orthosteric Ligand	ep4_off
5.26	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
5.26	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
5.26	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
5.26	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.26	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.26	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
5.26	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
5.26	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
5.00	Single	2YDV	NECA	2YDV-A_2A-NECA
5.00	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
5.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
5.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
5.00	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
5.00	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
5.00	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
5.00	Single	5G53	NECA	5G53-A_2A-NECA-Gs
5.00	Single	5TZR	MK8666	5TZR-FFA1-MK8666
5.00	Single	5XR8	AM841	5XR8-CB₁-AM841
5.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.00	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
5.00	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.00	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
5.00	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
5.00	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
5.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
5.00	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
5.00	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
5.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
5.00	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
5.00	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
5.00	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.00	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
5.00	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
5.00	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
5.00	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
5.00	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
5.00	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
5.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
5.00	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
5.00	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
5.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
5.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
5.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
5.00	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
5.00	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
5.00	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
5.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
5.00	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
5.00	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
5.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
5.00	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
5.00	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
5.00	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
5.00	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
5.00	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
5.00	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
5.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
5.00	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
5.00	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.00	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
5.00	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
5.00	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
5.00	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
5.00	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.00	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
5.00	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
5.00	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
5.00	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
5.00	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
5.00	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
5.00	Single	9GE2	ML184	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
5.00	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	a2_on	Orthosteric Ligand	a2b_on
5.00	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
5.00	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
5.00	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
5.00	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
5.00	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.00	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
5.00	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
5.00	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
5.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
5.00	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
5.00	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
5.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.00	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.00	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
5.00	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
5.00	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
5.00	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
5.00	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
5.00	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
5.00	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
5.00	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.00	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
5.00	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
5.00	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
5.00	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.00	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
4.76	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
4.76	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
4.76	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
4.76	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
4.76	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
4.76	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
4.76	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
4.76	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
4.76	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
4.76	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
4.76	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.76	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
4.76	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
4.76	Single	6OS2	TRV026	6OS2-AT₁-TRV026
4.76	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
4.76	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.76	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
4.76	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
4.76	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
4.76	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
4.76	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
4.76	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.76	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.76	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.76	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
4.76	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
4.76	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
4.76	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
4.76	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
4.76	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
4.76	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
4.76	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
4.76	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
4.76	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
4.76	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
4.76	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
4.76	Single	8JWY	2-118	8JWY-A_2A-2-118
4.76	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
4.76	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
4.76	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
4.76	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
4.76	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.76	Single	8XJN	Cloprosetnol	8XJN-TP-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8XQJ	JN241	8XQJ-Apelin-JN241
4.76	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
4.76	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
4.76	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.76	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.76	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
4.76	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
4.76	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
4.76	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
4.76	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.76	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
4.76	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
4.76	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
4.76	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
4.76	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
4.76	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
4.76	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.76	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
4.76	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
4.76	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
4.76	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
4.76	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
4.76	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
4.76	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
4.76	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.76	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
4.76	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.76	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.55	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
4.55	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
4.55	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
4.55	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
4.55	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
4.55	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
4.55	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
4.55	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
4.55	Single	7EZC	UKA	7EZC-A_2A-UKA
4.55	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.55	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
4.55	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
4.55	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
4.55	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
4.55	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
4.55	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
4.55	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
4.55	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
4.55	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
4.55	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
4.55	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
4.55	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
4.55	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
4.55	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
4.55	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
4.55	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
4.55	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
4.55	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
4.55	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
4.55	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
4.55	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
4.55	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
4.55	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
4.55	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
4.55	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
4.55	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
4.55	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
4.55	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.55	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
4.55	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
4.55	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.55	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.55	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
4.55	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
4.55	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
4.55	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
4.55	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
4.55	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
4.55	Consensus	tp_on	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
4.35	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
4.35	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
4.35	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
4.35	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
4.35	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
4.35	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
4.35	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
4.35	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.35	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
4.35	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
4.35	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.35	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
4.35	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
4.35	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
4.35	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
4.35	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.35	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
4.35	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
4.35	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
4.35	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.35	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
4.35	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
4.35	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
4.35	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
4.35	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
4.35	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.35	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
4.35	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
4.35	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
4.35	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
4.35	Single	8XQJ	JN241	8XQJ-Apelin-JN241
4.35	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
4.35	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
4.35	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
4.35	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
4.35	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
4.35	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.35	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
4.35	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.35	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.35	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
4.35	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
4.35	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
4.17	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
4.17	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
4.17	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
4.17	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
4.17	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
4.17	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
4.17	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Single	7QA8	Peptide	7QA8-STE2-Peptide
4.17	Single	7QA8	Peptide	7QA8-STE2-Peptide
4.17	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
4.17	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
4.17	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
4.17	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
4.17	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.17	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
4.17	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.17	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.17	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.17	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.17	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
4.17	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
4.17	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
4.17	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
4.17	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
4.17	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
4.17	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.17	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.17	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
4.17	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
4.17	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
4.17	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
4.17	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
4.17	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.17	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.17	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
4.00	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
4.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
4.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
4.00	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
4.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
4.00	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
4.00	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
4.00	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
4.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
4.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
4.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
4.00	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
4.00	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
4.00	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
4.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.00	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
4.00	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
4.00	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
4.00	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
4.00	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
4.00	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
4.00	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
4.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
4.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
4.00	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
4.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
4.00	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.00	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
4.00	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
4.00	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
4.00	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
3.85	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
3.85	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
3.85	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
3.85	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
3.85	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.85	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
3.85	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.85	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
3.85	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
3.85	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.85	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
3.85	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
3.85	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.85	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.85	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
3.85	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
3.85	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
3.85	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.85	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.85	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.85	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.85	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.85	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
3.85	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
3.85	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.85	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.85	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
3.85	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
3.85	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
3.85	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
3.70	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
3.70	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
3.70	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
3.70	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
3.70	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
3.70	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.70	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.70	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
3.70	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
3.70	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.70	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
3.70	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
3.70	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.70	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
3.70	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
3.70	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
3.70	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
3.70	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
3.57	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
3.57	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
3.57	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
3.57	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.57	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.57	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
3.57	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
3.57	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
3.57	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
3.57	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
3.57	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
3.57	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
3.57	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
3.57	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
3.57	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.57	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
3.57	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
3.57	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.57	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.45	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
3.45	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
3.45	Single	6FJ3	PTH	6FJ3-PTH1-PTH
3.45	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
3.45	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
3.45	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.45	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
3.45	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.45	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.45	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
3.45	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
3.45	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
3.45	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
3.45	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.45	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
3.33	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
3.33	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
3.33	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
3.33	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
3.33	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
3.33	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
3.33	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
3.33	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
3.33	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
3.33	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
3.33	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
3.33	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
3.33	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
3.23	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
3.23	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
3.23	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
3.12	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
3.12	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.12	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.12	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
3.12	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
3.12	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
3.12	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.03	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.03	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
2.94	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
2.86	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
2.70	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.70	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.33	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

PDB Summary
PDB	8JHY
Class	A
SubFamily	Alicarboxylic acid
Type	Hydroxycarboxylic Acid
SubType	HCA2
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	Compound 9n
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	2.87
Date	2023-09-06
D.O.I.	10.1016/j.molcel.2023.07.030

Net Summary
I_min	1.74
Number of Linked Nodes	864
Number of Links	1123
Number of Hubs	194
Number of Links mediated by Hubs	706
Number of Communities	30
Number of Nodes involved in Communities	317
Number of Links involved in Communities	466

Path Summary
Number Of Nodes in MetaPath	90
Number Of Links MetaPath	89
Number of Shortest Paths	1663901
Length Of Smallest Path	3
Average Path Length	27.0526
Length of Longest Path	59
Minimum Path Strength	1.03
Average Path Strength	4.99325
Maximum Path Strength	22.68
Minimum Path Correlation	0.7
Average Path Correlation	0.985516
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.5641
Average % Of Corr. Nodes	47.6438
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.7752
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • nicotinic acid receptor activity • myeloid cell apoptotic process • multicellular organismal process • homeostatic process • leukocyte apoptotic process • cell death • neutrophil homeostasis • neutrophil apoptotic process • multicellular organismal-level homeostasis • leukocyte homeostasis • inflammatory cell apoptotic process • homeostasis of number of cells • apoptotic process • myeloid cell homeostasis • programmed cell death • positive regulation of cell communication • establishment of protein localization • system process • nitrogen compound transport • regulation of adiponectin secretion • positive regulation of establishment of protein localization • positive regulation of adiponectin secretion • adiponectin secretion • regulation of biological quality • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • endocrine hormone secretion • positive regulation of multicellular organismal process • regulation of hormone secretion • transport • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • secretion by cell • regulation of secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • signal release • regulation of multicellular organismal process • regulation of signaling • secretion • regulation of transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • positive regulation of protein secretion • endocrine process • positive regulation of transport • protein transport • hormone transport • regulation of cell communication • positive regulation of signaling • regulation of programmed cell death • regulation of neutrophil apoptotic process • positive regulation of myeloid cell apoptotic process • positive regulation of neutrophil apoptotic process • regulation of immune system process • positive regulation of leukocyte apoptotic process • positive regulation of immune system process • regulation of leukocyte apoptotic process • positive regulation of programmed cell death • regulation of apoptotic process • positive regulation of apoptotic process • regulation of myeloid cell apoptotic process • negative regulation of catabolic process • lipid catabolic process • catabolic process • negative regulation of metabolic process • negative regulation of biological process • regulation of catabolic process • regulation of lipid catabolic process • negative regulation of cellular process • negative regulation of lipid metabolic process • negative regulation of lipid catabolic process
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	IX8
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	IX8
Name	7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide
Synonyms
Identifier
Formula	C26 H28 N4 O2
Molecular Weight	428.526
SMILES
PubChem	25101223
Formal Charge	0
Total Atoms	60
Total Chiral Atoms	1
Total Bonds	63
Total Aromatic Bonds	22


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8JHY_Chain_A G C T L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K N T I V K Q M K I G I V E T H F T F K D L H F K M F D V G A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E D E E M N R M H A S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8JHY_Chain_B G S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8JHY_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q8TDS4
Sequence	>8JHY_Chain_R F L E I D K K N C C V F R D D F I V K V L P P V L G L E F I F G L L G N G L A L W I F C F H L K S W K S S R I F L F N L A V A D F L L I I C L P F L M D N Y V R R W D W K F G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H P H H A L N K I S N R T A A I I S C L L W G I T I G L T V H L L K K K M P I Q N G G A N L C S S F S I C H T F Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q M D R H A K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S G T Q N C E V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8J6L	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.05	2024-04-03	10.1016/j.celrep.2023.113406
	8J6L (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.05	2024-04-03	10.1016/j.celrep.2023.113406
	8J6I	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.92	2024-04-03	10.1016/j.celrep.2023.113406
	8J6I (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.92	2024-04-03	10.1016/j.celrep.2023.113406
	8JHN	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Go/β1/γ2	3.75	2024-03-06	10.1038/s41467-024-46239-2
	8JHN (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		3.75	2024-03-06	10.1038/s41467-024-46239-2
	8JER	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Go/β1/γ2	3.45	2024-03-06	10.1038/s41467-024-46239-2
	8JER (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.45	2024-03-06	10.1038/s41467-024-46239-2
	8IYW	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Go/β1/γ2	3.45	2024-03-06	10.1038/s41467-024-46239-2
	8IYW (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.45	2024-03-06	10.1038/s41467-024-46239-2
	8IYH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Go/β1/γ2	3.3	2024-03-06	10.1038/s41467-024-46239-2
	8IYH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.3	2024-03-06	10.1038/s41467-024-46239-2
	8IY9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Go/β1/γ2	3.37	2024-03-06	10.1038/s41467-024-46239-2
	8IY9 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.37	2024-03-06	10.1038/s41467-024-46239-2
	8I7W	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	3.39	2024-02-07	10.1038/s41467-023-42764-8
	8I7W (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.39	2024-02-07	10.1038/s41467-023-42764-8
	8I7V	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	2.77	2024-02-07	10.1038/s41467-023-42764-8
	8I7V (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		2.77	2024-02-07	10.1038/s41467-023-42764-8
	8J6J	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.8	2024-01-10	10.1016/j.celrep.2023.113406
	8J6J (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.8	2024-01-10	10.1016/j.celrep.2023.113406
	8IJD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.25	2024-01-03	10.1038/s41421-023-00610-7
	8IJD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.25	2024-01-03	10.1038/s41421-023-00610-7
	8IJB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	3.23	2024-01-03	10.1038/s41421-023-00610-7
	8IJB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.23	2024-01-03	10.1038/s41421-023-00610-7
	8IJA	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.69	2024-01-03	10.1038/s41421-023-00610-7
	8IJA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		2.69	2024-01-03	10.1038/s41421-023-00610-7
	8IJ3	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	Gi1/β1/γ2	3.28	2024-01-03	10.1038/s41421-023-00610-7
	8IJ3 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-		3.28	2024-01-03	10.1038/s41421-023-00610-7
	8J6R	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.76	2023-12-06	10.1038/s41467-023-43537-z
	8J6R (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.76	2023-12-06	10.1038/s41467-023-43537-z
	8J6Q	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n	Gi1/β1/γ2	2.6	2023-12-06	10.1038/s41467-023-43537-z
	8J6Q (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n		2.6	2023-12-06	10.1038/s41467-023-43537-z
	8J6P	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	2.55	2023-12-06	10.1038/s41467-023-43537-z
	8J6P (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		2.55	2023-12-06	10.1038/s41467-023-43537-z
	8K5D	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	-	3.74	2023-11-22	10.1038/s41467-023-42764-8
	8K5C	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	-	3.13	2023-11-22	10.1038/s41467-023-42764-8
	8K5B	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	-	3.43	2023-11-22	10.1038/s41467-023-42764-8
	8H2G	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.01	2023-10-11	To be published
	8H2G (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.01	2023-10-11	To be published
	8JZ7	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.6	2023-10-04	10.1038/s41392-023-01625-y
	8JZ7 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.6	2023-10-04	10.1038/s41392-023-01625-y
	8IHB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.85	2023-09-13	10.1038/s41467-023-41650-7
	8IHB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.85	2023-09-13	10.1038/s41467-023-41650-7
	8JIM	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Gi1/β1/γ2	2.98	2023-09-06	10.1016/j.molcel.2023.07.030
	8JIM (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		2.98	2023-09-06	10.1016/j.molcel.2023.07.030
	8JIL	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.5	2023-09-06	10.1016/j.molcel.2023.07.030
	8JIL (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.5	2023-09-06	10.1016/j.molcel.2023.07.030
	8JII	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	3.17	2023-09-06	10.1016/j.molcel.2023.07.030
	8JII (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		3.17	2023-09-06	10.1016/j.molcel.2023.07.030
	8JHY (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n		2.87	2023-09-06	10.1016/j.molcel.2023.07.030
	8IHI	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.11	2023-08-30	10.1038/s41467-023-41650-7
	8IHI (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-		3.11	2023-08-30	10.1038/s41467-023-41650-7
	8IHH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-	Gi1/β1/γ2	3.06	2023-08-30	10.1038/s41467-023-41650-7
	8IHH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-		3.06	2023-08-30	10.1038/s41467-023-41650-7
	8IHF	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.97	2023-08-30	10.1038/s41467-023-41650-7
	8IHF (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.97	2023-08-30	10.1038/s41467-023-41650-7
	7ZLY	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	10.1038/s41467-023-37177-6
	7ZL9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	10.1038/s41467-023-37177-6
	7XK2	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.1	2023-02-22	10.1038/s41467-023-37177-6
	7XK2 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.1	2023-02-22	10.1038/s41467-023-37177-6
	8UUJ	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-	Gi1/β1/γ2	2.62	2025-02-26	10.1016/j.cell.2024.11.001
	8UUJ (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-		2.62	2025-02-26	10.1016/j.cell.2024.11.001
	8UTD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	3.24	2025-02-26	10.1016/j.cell.2024.11.001
	8UTD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-		3.24	2025-02-26	10.1016/j.cell.2024.11.001
	9IQT	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	9IQT (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-		2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795

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