psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:L4	B:B:S2	3	No	No	14	4	5
2	B:B:D5	B:B:S2	2.94	No	No	14	1	5
3	B:B:E3	B:B:Q6	7.65	No	No	0	5	1
4	B:B:D5	B:B:L4	5.43	No	No	14	1	4
5	B:B:L4	G:G:S8	3	No	No	0	4	4
6	B:B:D5	B:B:R8	10.72	No	No	0	1	3
7	B:B:L7	G:G:A12	4.73	No	No	0	8	5
8	B:B:L7	G:G:R13	4.86	No	No	0	8	6
9	B:B:Q9	B:B:R8	9.35	No	No	0	3	3
10	B:B:E10	G:G:V16	7.13	No	Yes	0	8	7
11	B:B:L14	G:G:L19	4.15	No	No	0	8	9
12	B:B:L14	G:G:K20	4.23	No	No	0	8	6
13	B:B:N16	B:B:R19	9.64	No	No	0	1	4
14	B:B:I18	B:B:R22	3.76	No	No	0	7	6
15	B:B:I18	G:G:A23	3.25	No	No	0	7	8
16	B:B:D20	B:B:R19	5.96	No	No	0	2	4
17	B:B:A21	G:G:R27	2.77	No	Yes	0	4	8
18	B:B:D258	B:B:R22	9.53	Yes	No	4	7	6
19	B:B:R22	G:G:R27	3.2	No	Yes	4	6	8
20	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
21	B:B:D27	G:G:K29	9.68	No	No	0	8	4
22	B:B:D27	G:G:S31	7.36	No	No	0	8	9
23	B:B:A28	B:B:I33	3.25	No	No	0	4	3
24	B:B:A28	G:G:S31	3.42	No	No	0	4	9
25	B:B:S31	B:B:T29	4.8	No	No	0	1	3
26	B:B:Q32	B:B:T29	11.34	No	No	0	1	3
27	B:B:L30	B:B:M262	7.07	No	Yes	0	5	4
28	B:B:I33	B:B:T34	3.04	No	Yes	0	3	5
29	B:B:I33	G:G:A34	4.87	No	No	0	3	6
30	B:B:I37	B:B:T34	4.56	Yes	Yes	8	2	5
31	B:B:L300	B:B:T34	4.42	Yes	Yes	8	6	5
32	B:B:T34	G:G:M38	4.52	Yes	No	0	5	4
33	B:B:N35	B:B:N36	2.72	No	No	0	1	1
34	B:B:I37	B:B:R283	5.01	Yes	Yes	8	2	9
35	B:B:I37	B:B:L300	2.85	Yes	Yes	8	2	6
36	B:B:I37	B:B:K301	7.27	Yes	Yes	0	2	5
37	B:B:R283	B:B:V40	7.85	Yes	No	8	9	3
38	B:B:D298	B:B:V40	4.38	No	No	8	9	3
39	B:B:V40	G:G:L51	2.98	No	Yes	8	3	6
40	B:B:Q44	B:B:R42	2.34	No	No	0	4	2
41	B:B:G306	B:B:R42	4.5	No	No	0	4	2
42	B:B:I43	B:B:M45	2.92	No	No	0	3	4
43	B:B:I43	B:B:L284	4.28	No	Yes	0	3	5
44	B:B:A305	B:B:I43	3.25	No	No	0	4	3
45	B:B:L308	B:B:M45	5.65	No	No	0	7	4
46	B:B:R46	B:B:R48	7.46	No	Yes	0	5	7
47	B:B:K337	B:B:T47	6.01	Yes	No	7	6	3
48	B:B:T47	B:B:W339	8.49	No	Yes	7	3	9
49	B:B:R48	B:B:R49	2.13	Yes	Yes	3	7	7
50	B:B:N340	B:B:R48	9.64	No	Yes	3	9	7
51	B:B:R48	G:G:N59	3.62	Yes	No	3	7	9
52	B:B:R48	G:G:F61	2.14	Yes	Yes	3	7	8
53	B:B:I338	B:B:R49	2.51	No	Yes	3	5	7
54	B:B:R49	G:G:F61	3.21	Yes	Yes	3	7	8
55	B:B:R49	G:G:E63	3.49	Yes	No	0	7	6
56	B:B:R52	B:B:T50	5.17	No	No	0	7	3
57	B:B:K337	B:B:T50	4.5	Yes	No	0	6	3
58	B:B:L51	B:B:W82	17.08	Yes	Yes	3	9	9
59	B:B:L336	B:B:L51	8.3	Yes	Yes	3	7	9
60	B:B:I338	B:B:L51	2.85	No	Yes	3	5	9
61	B:B:F335	B:B:R52	9.62	No	No	0	4	7
62	B:B:R52	R:R:R63	11.73	No	No	0	7	6
63	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
64	B:B:H54	B:B:I58	9.28	Yes	No	0	9	9
65	B:B:H54	B:B:S72	5.58	Yes	No	3	9	9
66	B:B:H54	B:B:S74	12.55	Yes	No	3	9	9
67	B:B:D76	B:B:H54	2.52	Yes	Yes	3	9	9
68	B:B:H54	B:B:K78	2.62	Yes	Yes	3	9	8
69	B:B:H54	B:B:I80	13.26	Yes	No	3	9	8
70	B:B:A56	B:B:D76	3.09	No	Yes	0	7	9
71	B:B:K57	B:B:Y59	4.78	No	Yes	1	9	8
72	B:B:K57	B:B:W332	25.53	No	Yes	1	9	9
73	A:A:E216	B:B:K57	5.4	No	No	0	7	9
74	B:B:I58	B:B:L336	2.85	No	Yes	0	9	7
75	B:B:Q75	B:B:Y59	20.29	No	Yes	1	9	8
76	B:B:M101	B:B:Y59	2.39	No	Yes	0	9	8
77	B:B:W332	B:B:Y59	6.75	Yes	Yes	1	9	8
78	A:A:H213	B:B:Y59	5.44	Yes	Yes	1	8	8
79	A:A:C214	B:B:Y59	5.38	Yes	Yes	1	7	8
80	B:B:A60	B:B:C103	3.61	No	No	0	7	8
81	B:B:M61	B:B:W63	3.49	Yes	Yes	3	6	7
82	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
83	B:B:A328	B:B:M61	3.22	No	Yes	3	5	6
84	B:B:L336	B:B:M61	4.24	Yes	Yes	3	7	6
85	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
86	B:B:H62	B:B:R150	14.67	No	No	0	6	6
87	B:B:L70	B:B:W63	7.97	No	Yes	3	5	7
88	B:B:S84	B:B:W63	4.94	Yes	Yes	3	5	7
89	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
90	B:B:T321	B:B:W63	10.92	Yes	Yes	3	7	7
91	B:B:A328	B:B:W63	5.19	No	Yes	3	5	7
92	B:B:D66	B:B:R68	3.57	No	No	0	8	5
93	B:B:D66	B:B:L69	2.71	No	No	0	8	5
94	B:B:S67	B:B:T321	6.4	No	Yes	3	5	7
95	B:B:D323	B:B:S67	10.31	No	No	3	7	5
96	B:B:D83	B:B:R68	13.1	No	No	0	8	5
97	B:B:R68	B:B:Y85	27.78	No	Yes	0	5	4
98	B:B:D83	B:B:L69	4.07	No	No	0	8	5
99	B:B:L69	B:B:Y105	3.52	No	Yes	0	5	6
100	B:B:L70	B:B:W82	4.56	No	Yes	3	5	9
101	B:B:L70	B:B:S84	3	No	Yes	3	5	5
102	B:B:I81	B:B:V71	3.07	Yes	No	0	7	8
103	B:B:C103	B:B:V71	3.42	No	No	0	8	8
104	B:B:V71	B:B:Y105	3.79	No	Yes	0	8	6
105	B:B:S72	B:B:W82	6.18	No	Yes	3	9	9
106	B:B:L336	B:B:S72	4.5	Yes	No	3	7	9
107	B:B:A73	B:B:L79	3.15	No	Yes	0	9	7
108	B:B:A73	B:B:V100	3.39	No	No	0	9	9
109	B:B:D76	B:B:S74	8.83	Yes	No	3	9	9
110	B:B:Q75	B:B:W99	6.57	No	Yes	1	9	9
111	A:A:C214	B:B:Q75	9.16	Yes	No	1	7	9
112	B:B:D76	B:B:K78	8.3	Yes	Yes	3	9	8
113	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
114	B:B:G77	B:B:S98	1.86	No	No	0	8	8
115	B:B:K78	B:B:P94	3.35	Yes	No	0	8	5
116	A:A:L23	B:B:K78	4.23	No	Yes	3	6	8
117	B:B:I93	B:B:L79	2.85	Yes	Yes	6	7	7
118	B:B:L79	B:B:L95	4.15	Yes	Yes	6	7	8
119	B:B:C114	B:B:L79	3.17	Yes	Yes	6	8	7
120	B:B:I80	B:B:W82	14.09	No	Yes	3	8	9
121	B:B:I80	B:B:K89	2.91	No	Yes	3	8	9
122	B:B:I81	B:B:V90	3.07	Yes	No	6	7	5
123	B:B:H91	B:B:I81	6.63	Yes	Yes	6	5	7
124	B:B:I81	B:B:L126	4.28	Yes	Yes	6	7	5
125	B:B:K89	B:B:W82	11.6	Yes	Yes	3	9	9
126	B:B:L336	B:B:W82	3.42	Yes	Yes	3	7	9
127	B:B:D83	B:B:T86	8.67	No	No	0	8	6
128	B:B:S84	B:B:Y85	2.54	Yes	Yes	3	5	4
129	B:B:S84	G:G:F61	5.28	Yes	Yes	3	5	8
130	B:B:Y85	G:G:P60	8.34	Yes	No	0	4	9
131	B:B:Y85	G:G:F61	6.19	Yes	Yes	3	4	8
132	B:B:N88	B:B:T86	8.77	Yes	No	0	7	6
133	A:A:V13	B:B:N88	5.91	No	Yes	0	3	7
134	A:A:S16	B:B:N88	5.96	No	Yes	0	7	7
135	A:A:S16	B:B:K89	3.06	No	Yes	0	7	9
136	A:A:I19	B:B:K89	4.36	Yes	Yes	3	9	9
137	A:A:D20	B:B:K89	11.06	No	Yes	0	6	9
138	A:A:L23	B:B:K89	2.82	No	Yes	3	6	9
139	B:B:H91	B:B:V90	6.92	Yes	No	6	5	5
140	B:B:H91	B:B:V133	4.15	Yes	Yes	6	5	4
141	A:A:R15	B:B:H91	3.39	No	Yes	0	5	5
142	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
143	B:B:I93	B:B:Y124	4.84	Yes	Yes	6	7	6
144	B:B:I93	B:B:V133	6.14	Yes	Yes	6	7	4
145	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
146	B:B:C114	B:B:L95	3.17	Yes	Yes	6	8	8
147	B:B:L95	B:B:Y124	5.86	Yes	Yes	6	8	6
148	B:B:R96	B:B:V135	11.77	No	No	0	6	4
149	B:B:E138	B:B:R96	6.98	No	No	0	6	6
150	B:B:S97	B:B:W99	2.47	No	Yes	0	8	9
151	B:B:D118	B:B:S97	8.83	No	No	0	9	8
152	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
153	B:B:L117	B:B:W99	5.69	Yes	Yes	1	9	9
154	A:A:I184	B:B:W99	4.7	No	Yes	1	9	9
155	A:A:E186	B:B:W99	4.36	Yes	Yes	1	9	9
156	A:A:F199	B:B:W99	9.02	Yes	Yes	1	5	9
157	A:A:C214	B:B:W99	2.61	Yes	Yes	1	7	9
158	A:A:F215	B:B:W99	8.02	Yes	Yes	1	9	9
159	B:B:M101	B:B:Y145	4.79	No	Yes	0	9	8
160	B:B:G115	B:B:T102	1.82	No	No	0	9	8
161	B:B:C149	B:B:T102	5.07	No	No	0	8	8
162	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
163	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
164	B:B:V112	B:B:Y105	3.79	No	Yes	6	8	6
165	B:B:L126	B:B:Y105	3.52	Yes	Yes	6	5	6
166	B:B:A106	B:B:P107	1.87	No	No	1	6	6
167	B:B:A106	B:B:F151	5.55	No	Yes	1	6	9
168	B:B:F151	B:B:P107	2.89	Yes	No	1	9	6
169	B:B:G109	B:B:S108	1.86	No	No	0	5	6
170	B:B:N110	B:B:S108	7.45	Yes	No	1	4	6
171	B:B:D154	B:B:S108	8.83	No	No	1	6	6
172	B:B:N110	B:B:Y111	3.49	Yes	Yes	1	4	4
173	B:B:K127	B:B:N110	9.79	No	Yes	0	4	4
174	B:B:D154	B:B:N110	4.04	No	Yes	1	6	4
175	B:B:I123	B:B:Y111	3.63	Yes	Yes	1	6	4
176	B:B:N125	B:B:Y111	12.79	No	Yes	0	4	4
177	B:B:S136	B:B:Y111	3.82	No	Yes	1	4	4
178	B:B:F151	B:B:Y111	2.06	Yes	Yes	1	9	4
179	B:B:D154	B:B:Y111	8.05	No	Yes	1	6	4
180	B:B:V112	B:B:Y124	3.79	No	Yes	6	8	6
181	B:B:L126	B:B:V112	2.98	Yes	No	6	5	8
182	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
183	B:B:C114	B:B:G115	1.96	Yes	No	0	8	9
184	B:B:C114	B:B:Y124	5.38	Yes	Yes	6	8	6
185	B:B:G115	B:B:G116	2.11	No	No	0	9	9
186	B:B:L117	B:B:Y145	3.52	Yes	Yes	1	9	8
187	A:A:Q204	B:B:L117	2.66	Yes	Yes	1	9	9
188	A:A:W211	B:B:L117	3.42	Yes	Yes	1	9	9
189	A:A:F215	B:B:L117	2.44	Yes	Yes	1	9	9
190	B:B:D118	B:B:I120	5.6	No	No	0	9	6
191	B:B:G144	B:B:N119	5.09	No	Yes	1	8	9
192	A:A:T182	B:B:N119	5.85	No	Yes	1	7	9
193	A:A:G183	B:B:N119	5.09	No	Yes	1	9	9
194	A:A:Q204	B:B:N119	3.96	Yes	Yes	1	9	9
195	B:B:E138	B:B:I120	4.1	No	No	0	6	6
196	B:B:A140	B:B:I120	3.25	No	No	0	5	6
197	B:B:C121	B:B:L139	4.76	Yes	Yes	1	8	9
198	B:B:C121	B:B:L146	3.17	Yes	No	1	8	7
199	B:B:C121	B:B:C149	3.64	Yes	No	0	8	8
200	B:B:C121	B:B:T159	3.38	Yes	Yes	1	8	9
201	B:B:S122	B:B:Y124	3.82	No	Yes	0	8	6
202	B:B:E138	B:B:S122	5.75	No	No	0	6	8
203	B:B:I123	B:B:S136	3.1	Yes	No	1	6	4
204	B:B:I123	B:B:R137	2.51	Yes	No	1	6	5
205	B:B:I123	B:B:L139	2.85	Yes	Yes	1	6	9
206	B:B:F151	B:B:I123	2.51	Yes	Yes	1	9	6
207	B:B:I123	B:B:I171	4.42	Yes	Yes	1	6	6
208	B:B:V133	B:B:Y124	3.79	Yes	Yes	6	4	6
209	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
210	B:B:N125	B:B:T128	2.92	No	Yes	0	4	3
211	B:B:L126	B:B:V133	2.98	Yes	Yes	6	5	4
212	B:B:E130	B:B:T128	2.82	Yes	Yes	15	3	3
213	B:B:G131	B:B:T128	1.82	No	Yes	0	4	3
214	B:B:R134	B:B:T128	6.47	No	Yes	15	3	3
215	B:B:E130	B:B:R129	3.49	Yes	No	0	3	3
216	B:B:E130	B:B:N132	2.63	Yes	No	0	3	3
217	B:B:E130	B:B:R134	5.82	Yes	No	15	3	3
218	B:B:L139	B:B:R137	3.64	Yes	No	1	9	5
219	B:B:I171	B:B:R137	2.51	Yes	No	1	6	5
220	B:B:L139	B:B:W169	13.67	Yes	Yes	1	9	8
221	B:B:A140	B:B:G141	1.95	No	No	0	5	5
222	B:B:H142	B:B:L146	3.86	Yes	No	1	9	7
223	B:B:H142	B:B:T159	5.48	Yes	Yes	1	9	9
224	B:B:H142	B:B:S161	16.74	Yes	Yes	1	9	9
225	B:B:D163	B:B:H142	6.3	Yes	Yes	1	9	9
226	B:B:H142	B:B:T165	2.74	Yes	No	1	9	7
227	B:B:A167	B:B:H142	2.93	No	Yes	1	4	9
228	B:B:H142	B:B:W169	3.17	Yes	Yes	1	9	8
229	B:B:H142	B:B:Q176	3.71	Yes	Yes	1	9	4
230	B:B:D163	B:B:T143	8.67	Yes	No	0	9	5
231	B:B:G144	B:B:S161	1.86	No	Yes	1	8	9
232	B:B:G144	B:B:G162	2.11	No	Yes	1	8	9
233	B:B:G162	B:B:Y145	4.35	Yes	Yes	1	9	8
234	B:B:D186	B:B:Y145	5.75	Yes	Yes	1	9	8
235	A:A:Q204	B:B:Y145	2.25	Yes	Yes	1	9	8
236	A:A:S206	B:B:Y145	7.63	Yes	Yes	1	8	8
237	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
238	A:A:W211	B:B:Y145	4.82	Yes	Yes	1	9	8
239	B:B:L146	B:B:T159	4.42	No	Yes	1	7	9
240	B:B:S147	B:B:S160	3.26	No	No	0	9	6
241	B:B:C148	B:B:L190	4.76	No	Yes	0	6	5
242	B:B:L190	B:B:R150	2.43	Yes	No	0	5	6
243	B:B:L192	B:B:R150	2.43	Yes	No	0	5	6
244	B:B:F151	B:B:I157	7.54	Yes	No	1	9	7
245	B:B:F151	B:B:I171	3.77	Yes	Yes	1	9	6
246	B:B:D153	B:B:L152	2.71	No	Yes	0	5	3
247	B:B:L152	B:B:V158	2.98	Yes	Yes	0	3	5
248	B:B:L152	B:B:L192	6.92	Yes	Yes	5	3	5
249	B:B:L152	B:B:T196	4.42	Yes	No	5	3	1
250	B:B:D153	B:B:Q156	11.75	No	No	0	5	5
251	B:B:D170	B:B:N155	6.73	No	No	0	9	3
252	B:B:E172	B:B:N155	9.2	No	No	0	6	3
253	B:B:I157	B:B:W169	3.52	No	Yes	1	7	8
254	B:B:I157	B:B:I171	2.94	No	Yes	1	7	6
255	B:B:L168	B:B:V158	2.98	Yes	Yes	0	6	5
256	B:B:L190	B:B:V158	2.98	Yes	Yes	0	5	5
257	B:B:F199	B:B:V158	2.62	Yes	Yes	0	9	5
258	B:B:T159	B:B:W169	9.7	Yes	Yes	1	9	8
259	B:B:S160	B:B:V187	6.46	No	Yes	0	6	9
260	B:B:L190	B:B:S160	3	Yes	No	0	5	6
261	B:B:G162	B:B:S161	3.71	Yes	Yes	1	9	9
262	B:B:D163	B:B:S161	7.36	Yes	Yes	1	9	9
263	B:B:D186	B:B:G162	5.03	Yes	Yes	1	9	9
264	B:B:D163	B:B:T165	13.01	Yes	No	1	9	7
265	B:B:G185	B:B:T164	1.82	No	No	0	5	6
266	B:B:T165	B:B:T181	3.14	No	No	0	7	2
267	B:B:C166	B:B:F180	4.19	Yes	Yes	5	8	7
268	B:B:C166	B:B:V187	3.42	Yes	Yes	5	8	9
269	B:B:C166	B:B:F199	4.19	Yes	Yes	5	8	9
270	B:B:C166	B:B:S201	3.44	Yes	Yes	5	8	9
271	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
272	B:B:A167	B:B:Q176	4.55	No	Yes	1	4	4
273	B:B:L168	B:B:T177	2.95	Yes	No	5	6	4
274	B:B:L168	B:B:T178	7.37	Yes	Yes	5	6	4
275	B:B:F180	B:B:L168	2.44	Yes	Yes	5	7	6
276	B:B:Q176	B:B:W169	17.52	Yes	Yes	1	4	8
277	B:B:D170	B:B:T173	7.23	No	No	0	9	5
278	B:B:G174	B:B:T173	1.82	No	No	0	4	5
279	B:B:Q175	B:B:T173	4.25	No	No	0	4	5
280	B:B:Q176	B:B:T179	4.25	Yes	No	0	4	4
281	B:B:T177	B:B:T178	4.71	No	Yes	5	4	4
282	B:B:F180	B:B:T178	3.89	Yes	Yes	5	7	4
283	B:B:G216	B:B:T178	1.82	No	Yes	5	4	4
284	B:B:F180	B:B:F199	12.86	Yes	Yes	5	7	9
285	B:B:F180	B:B:W211	13.03	Yes	Yes	5	7	8
286	B:B:F180	B:B:G216	3.01	Yes	No	5	7	4
287	B:B:G182	B:B:T181	1.82	No	No	0	6	2
288	B:B:H183	B:B:V187	4.15	Yes	Yes	5	9	9
289	B:B:H183	B:B:S201	5.58	Yes	Yes	5	9	9
290	B:B:A203	B:B:H183	8.78	No	Yes	5	8	9
291	B:B:D205	B:B:H183	7.56	Yes	Yes	5	9	9
292	B:B:H183	B:B:S207	2.79	Yes	Yes	5	9	5
293	B:B:H183	B:B:K209	14.41	Yes	Yes	5	9	6
294	B:B:D205	B:B:T184	7.23	Yes	No	0	9	3
295	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
296	A:A:S206	B:B:D186	4.42	Yes	Yes	1	8	9
297	A:A:E207	B:B:D186	2.6	No	Yes	1	9	9
298	B:B:S201	B:B:V187	3.23	Yes	Yes	5	9	9
299	B:B:A203	B:B:V187	3.39	No	Yes	5	8	9
300	B:B:C204	B:B:M188	3.24	Yes	No	1	7	8
301	A:A:K210	B:B:M188	4.32	Yes	No	1	9	8
302	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
303	B:B:L192	B:B:T196	2.95	Yes	No	5	5	1
304	B:B:F199	B:B:L192	2.44	Yes	Yes	5	9	5
305	B:B:A193	B:B:P194	1.87	No	No	0	4	4
306	B:B:A193	B:B:D195	4.63	No	No	0	4	5
307	B:B:A193	B:B:F234	2.77	No	Yes	0	4	5
308	B:B:G238	B:B:P194	4.06	No	No	0	7	4
309	B:B:D195	B:B:R197	4.76	No	No	0	5	5
310	B:B:R197	B:B:R214	14.93	No	No	0	5	9
311	B:B:L198	B:B:L210	2.77	No	Yes	0	3	5
312	B:B:D212	B:B:L198	5.43	Yes	No	0	9	3
313	B:B:F199	B:B:W211	13.03	Yes	Yes	5	9	8
314	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
315	B:B:L210	B:B:V200	2.98	Yes	Yes	0	5	6
316	B:B:I232	B:B:V200	4.61	Yes	Yes	4	8	6
317	B:B:F234	B:B:V200	5.24	Yes	Yes	0	5	6
318	B:B:F241	B:B:V200	3.93	Yes	Yes	4	6	6
319	B:B:S201	B:B:W211	7.41	Yes	Yes	5	9	8
320	B:B:A203	B:B:D205	3.09	No	Yes	5	8	9
321	B:B:C204	B:B:D228	12.45	Yes	No	1	7	9
322	A:A:K210	B:B:C204	6.47	Yes	Yes	1	9	7
323	B:B:D205	B:B:S207	8.83	Yes	Yes	5	9	5
324	B:B:S207	B:B:T221	3.2	Yes	No	0	5	7
325	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
326	B:B:K209	B:B:W211	8.12	Yes	Yes	5	6	8
327	B:B:C218	B:B:K209	8.08	No	Yes	5	5	6
328	B:B:K209	B:B:T221	12.01	Yes	No	0	6	7
329	B:B:L210	B:B:R219	2.43	Yes	No	0	5	5
330	B:B:L210	B:B:Q220	2.66	Yes	Yes	0	5	7
331	B:B:L210	B:B:L255	2.77	Yes	Yes	0	5	6
332	B:B:C218	B:B:W211	7.84	No	Yes	5	5	8
333	B:B:D212	B:B:R214	5.96	Yes	No	16	9	9
334	B:B:D212	B:B:E215	6.5	Yes	No	16	9	3
335	B:B:D212	B:B:R219	7.15	Yes	No	0	9	5
336	B:B:E215	B:B:R214	3.49	No	No	16	3	9
337	B:B:M217	B:B:R219	6.2	No	No	0	3	5
338	B:B:M217	G:G:M21	2.89	No	No	0	3	1
339	B:B:C218	G:G:Q18	3.05	No	No	0	5	9
340	B:B:F222	B:B:Q220	7.03	Yes	Yes	4	8	7
341	B:B:D258	B:B:Q220	11.75	Yes	Yes	4	7	7
342	B:B:Q220	G:G:I25	2.74	Yes	No	4	7	2
343	B:B:T221	G:G:E22	8.47	No	No	0	7	9
344	B:B:F222	B:B:F241	8.57	Yes	Yes	4	8	6
345	B:B:F222	B:B:F253	9.65	Yes	Yes	4	8	6
346	B:B:F222	B:B:L255	2.44	Yes	Yes	4	8	6
347	B:B:D258	B:B:F222	4.78	Yes	Yes	4	7	8
348	B:B:G224	B:B:T223	1.82	No	No	0	6	2
349	B:B:H225	B:B:I229	9.28	Yes	Yes	4	9	7
350	B:B:H225	B:B:T243	6.85	Yes	Yes	4	9	8
351	B:B:H225	B:B:S245	16.74	Yes	No	4	9	9
352	B:B:D247	B:B:H225	5.04	Yes	Yes	4	9	9
353	B:B:H225	B:B:T249	2.74	Yes	Yes	4	9	6
354	B:B:H225	B:B:R251	18.05	Yes	Yes	4	9	8
355	B:B:D247	B:B:E226	9.09	Yes	No	0	9	3
356	B:B:D246	B:B:S227	2.94	No	No	0	9	6
357	B:B:D247	B:B:S227	2.94	Yes	No	0	9	6
358	A:A:K209	B:B:D228	5.53	No	No	1	8	9
359	A:A:K210	B:B:D228	8.3	Yes	No	1	9	9
360	B:B:I229	B:B:T243	6.08	Yes	Yes	4	7	8
361	B:B:I229	B:B:S245	3.1	Yes	No	4	7	9
362	B:B:D246	B:B:N230	6.73	No	No	0	9	9
363	A:A:K210	B:B:N230	5.6	Yes	No	0	9	9
364	B:B:A231	B:B:V276	5.09	No	No	0	5	6
365	B:B:F241	B:B:I232	3.77	Yes	Yes	4	6	8
366	B:B:I232	B:B:T243	4.56	Yes	Yes	4	8	8
367	B:B:C233	B:B:V276	3.42	No	No	0	3	6
368	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
369	B:B:F234	B:B:L255	2.44	Yes	Yes	0	5	6
370	B:B:F235	B:B:P236	18.78	Yes	Yes	9	6	7
371	B:B:F235	B:B:N237	2.42	Yes	No	9	6	5
372	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
373	B:B:F235	B:B:F278	7.5	Yes	Yes	9	6	7
374	B:B:F235	B:B:G282	3.01	Yes	No	9	6	9
375	B:B:F235	G:G:Y40	4.13	Yes	Yes	9	6	6
376	B:B:F278	B:B:P236	4.33	Yes	Yes	9	7	7
377	B:B:G282	B:B:P236	4.06	No	Yes	9	9	7
378	B:B:P236	G:G:Y40	5.56	Yes	Yes	9	7	6
379	B:B:N237	B:B:N239	6.81	No	No	0	5	2
380	B:B:N237	G:G:Y40	11.63	No	Yes	9	5	6
381	B:B:N239	B:B:R256	6.03	No	No	0	2	9
382	B:B:A240	B:B:D254	3.09	No	Yes	0	6	9
383	B:B:F241	B:B:T243	2.59	Yes	Yes	4	6	8
384	B:B:F241	B:B:F253	10.72	Yes	Yes	4	6	6
385	B:B:F241	B:B:L255	2.44	Yes	Yes	4	6	6
386	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
387	B:B:F253	B:B:T243	5.19	Yes	Yes	4	6	8
388	B:B:C250	B:B:G244	1.96	No	No	0	8	5
389	B:B:G244	B:B:V276	1.84	No	No	0	5	6
390	B:B:D247	B:B:S245	7.36	Yes	No	4	9	9
391	B:B:D247	B:B:T249	11.56	Yes	Yes	4	9	6
392	B:B:R251	B:B:T249	3.88	Yes	Yes	4	8	6
393	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
394	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
395	B:B:C250	B:B:I273	3.27	No	No	0	8	6
396	B:B:F253	B:B:R251	3.21	Yes	Yes	4	6	8
397	B:B:E260	B:B:R251	11.63	No	Yes	4	6	8
398	B:B:R251	B:B:T263	5.17	Yes	No	4	8	1
399	B:B:L252	B:B:L261	5.54	No	No	0	7	5
400	B:B:L252	B:B:M262	2.83	No	Yes	1	7	4
401	B:B:L252	B:B:Y264	5.86	No	Yes	1	7	5
402	B:B:E260	B:B:F253	5.83	No	Yes	4	6	6
403	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
404	B:B:D254	B:B:L261	5.43	Yes	No	0	9	5
405	B:B:D254	G:G:A33	3.09	Yes	No	0	9	7
406	B:B:D254	G:G:L37	2.71	Yes	No	0	9	7
407	B:B:R256	G:G:I28	2.51	No	No	0	9	4
408	B:B:R256	G:G:D36	8.34	No	No	0	9	5
409	B:B:D258	G:G:I25	7	Yes	No	4	7	2
410	B:B:D258	G:G:R27	9.53	Yes	Yes	4	7	8
411	B:B:Q259	G:G:V30	4.3	Yes	No	0	6	8
412	B:B:E260	B:B:T263	4.23	No	No	4	6	1
413	B:B:M262	B:B:Y264	10.78	Yes	Yes	1	4	5
414	B:B:A302	B:B:M262	4.83	No	Yes	1	2	4
415	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
416	B:B:W297	B:B:Y264	6.75	Yes	Yes	1	8	5
417	B:B:A302	B:B:Y264	2.67	No	Yes	1	2	5
418	B:B:H266	B:B:N268	10.2	Yes	No	0	4	4
419	B:B:H266	B:B:I269	2.65	Yes	No	0	4	4
420	B:B:H266	B:B:R304	2.26	Yes	Yes	0	4	5
421	B:B:I269	B:B:Y289	7.25	No	Yes	0	4	7
422	B:B:C271	B:B:G272	1.96	Yes	No	1	5	4
423	B:B:C271	B:B:Y289	4.03	Yes	Yes	1	5	7
424	B:B:C271	B:B:D290	4.67	Yes	Yes	1	5	6
425	B:B:C271	B:B:D291	6.22	Yes	No	1	5	8
426	B:B:D290	B:B:G272	5.03	Yes	No	1	6	4
427	B:B:I273	B:B:Y289	8.46	No	Yes	0	6	7
428	B:B:S275	B:B:T274	4.8	No	Yes	0	8	8
429	B:B:G288	B:B:T274	1.82	No	Yes	0	7	8
430	B:B:D290	B:B:T274	2.89	Yes	Yes	1	6	8
431	B:B:R314	B:B:T274	2.59	Yes	Yes	1	8	8
432	B:B:L318	B:B:S275	6.01	No	No	0	6	8
433	B:B:G319	B:B:S277	1.86	No	No	0	5	5
434	B:B:S277	B:B:V320	4.85	No	Yes	0	5	7
435	B:B:F278	B:B:L285	6.09	Yes	No	0	7	6
436	B:B:G282	B:B:S279	1.86	No	No	0	9	9
437	B:B:L284	B:B:S279	3	Yes	No	0	5	9
438	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
439	B:B:G324	B:B:K280	3.49	Yes	No	0	9	1
440	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
441	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
442	B:B:D298	B:B:R283	13.1	No	Yes	8	9	9
443	B:B:L300	B:B:R283	7.29	Yes	Yes	8	6	9
444	B:B:R283	G:G:L51	3.64	Yes	Yes	8	9	6
445	B:B:L284	B:B:V296	5.96	Yes	No	0	5	5
446	B:B:L284	G:G:L51	4.15	Yes	Yes	0	5	6
447	B:B:C294	B:B:L286	3.17	No	No	0	5	7
448	B:B:L286	B:B:V296	2.98	No	No	0	7	5
449	B:B:A287	B:B:Y289	4	No	Yes	0	6	7
450	B:B:G288	B:B:V315	1.84	No	No	0	7	7
451	B:B:D291	B:B:Y289	3.45	No	Yes	1	8	7
452	B:B:N295	B:B:Y289	13.96	Yes	Yes	1	6	7
453	B:B:W297	B:B:Y289	4.82	Yes	Yes	1	8	7
454	B:B:D290	B:B:R314	21.44	Yes	Yes	1	6	8
455	B:B:D291	B:B:N293	12.12	No	No	0	8	5
456	B:B:F292	B:B:N313	2.42	No	No	0	4	7
457	B:B:F292	R:R:R318	8.55	No	No	0	4	4
458	B:B:A309	B:B:N293	3.13	No	No	0	3	5
459	B:B:N293	R:R:S322	4.47	No	No	0	5	4
460	B:B:C294	B:B:L308	7.94	No	No	0	5	7
461	B:B:N295	B:B:W297	5.65	Yes	Yes	1	6	8
462	B:B:N295	B:B:R304	12.05	Yes	Yes	1	6	5
463	B:B:N295	B:B:V307	4.43	Yes	No	1	6	3
464	B:B:A305	B:B:V296	3.39	No	No	0	4	5
465	B:B:R304	B:B:W297	6	Yes	Yes	1	5	8
466	B:B:D298	B:B:K301	6.91	No	Yes	0	9	5
467	B:B:L300	G:G:C41	6.35	Yes	No	0	6	7
468	B:B:D303	B:B:K301	2.77	No	Yes	0	2	5
469	B:B:R304	B:B:V307	3.92	Yes	No	1	5	3
470	B:B:A305	B:B:G306	1.95	No	No	0	4	4
471	B:B:G306	B:B:V307	1.84	No	No	0	4	3
472	B:B:L308	B:B:W339	12.53	No	Yes	0	7	9
473	B:B:G310	R:R:C319	1.96	No	No	0	5	9
474	B:B:H311	B:B:V315	4.15	Yes	No	7	9	7
475	B:B:H311	B:B:T329	5.48	Yes	Yes	7	9	8
476	B:B:H311	B:B:S331	12.55	Yes	No	7	9	9
477	B:B:D333	B:B:H311	7.56	Yes	Yes	7	9	9
478	B:B:H311	B:B:K337	9.17	Yes	Yes	7	9	6
479	B:B:D312	B:B:D333	3.99	No	Yes	0	5	9
480	B:B:D312	R:R:K61	6.91	No	No	0	5	5
481	B:B:D312	R:R:S315	2.94	No	No	0	5	5
482	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
483	B:B:R314	B:B:W332	16.99	Yes	Yes	1	8	9
484	A:A:W258	B:B:R314	3	Yes	Yes	1	5	8
485	B:B:T329	B:B:V315	3.17	Yes	No	7	8	7
486	B:B:C317	B:B:S316	3.44	No	No	0	7	9
487	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
488	B:B:C317	B:B:G330	1.96	No	Yes	0	7	5
489	B:B:L318	B:B:T329	2.95	No	Yes	0	6	8
490	B:B:G324	B:B:V320	1.84	Yes	Yes	0	9	7
491	B:B:V320	B:B:V327	3.21	Yes	No	0	7	6
492	B:B:D323	B:B:T321	4.34	No	Yes	3	7	7
493	B:B:G324	B:B:T321	1.82	Yes	Yes	0	9	7
494	B:B:D323	B:B:M325	6.93	No	No	0	7	5
495	B:B:G324	G:G:P49	2.03	Yes	Yes	0	9	7
496	B:B:M325	G:G:P49	5.03	No	Yes	0	5	7
497	B:B:M325	G:G:P60	5.03	No	No	0	5	9
498	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
499	B:B:V327	B:B:W339	3.68	No	Yes	0	6	9
500	B:B:G330	B:B:T329	1.82	Yes	Yes	0	5	8
501	B:B:T329	B:B:W339	4.85	Yes	Yes	7	8	9
502	B:B:G330	B:B:S331	1.86	Yes	No	0	5	9
503	B:B:G330	B:B:L336	3.42	Yes	Yes	0	5	7
504	B:B:D333	B:B:S331	7.36	Yes	No	7	9	9
505	A:A:H213	B:B:W332	6.35	Yes	Yes	1	8	9
506	A:A:W258	B:B:W332	3.75	Yes	Yes	1	5	9
507	B:B:D333	B:B:F335	10.75	Yes	No	0	9	4
508	B:B:F335	B:B:S334	3.96	No	No	0	4	4
509	B:B:K337	B:B:W339	5.8	Yes	Yes	7	6	9
510	B:B:I338	G:G:F61	5.02	No	Yes	3	5	8
511	B:B:N340	G:G:N59	8.17	No	No	3	9	9
512	B:B:N340	G:G:F61	3.62	No	Yes	3	9	8
513	A:A:G2	A:A:L5	5.13	No	Yes	0	6	2
514	A:A:D9	A:A:L5	8.14	No	Yes	0	4	2
515	A:A:D9	A:A:S6	4.42	No	No	0	4	7
516	A:A:K17	A:A:V13	4.55	No	No	0	4	3
517	A:A:I19	A:A:R15	2.51	Yes	No	0	9	5
518	A:A:M18	A:A:R21	4.96	No	No	0	4	4
519	A:A:I19	A:A:L23	2.85	Yes	No	3	9	6
520	A:A:R21	A:A:R24	2.13	No	No	0	4	3
521	A:A:E25	A:A:R21	3.49	No	No	0	4	4
522	A:A:E28	R:R:K146	8.1	No	No	0	4	6
523	A:A:A31	A:A:R32	4.15	No	No	0	4	4
524	A:A:R32	R:R:F142	7.48	No	No	0	4	5
525	A:A:R32	R:R:H145	23.7	No	No	0	4	7
526	A:A:E33	A:A:K35	2.7	No	No	0	6	9
527	A:A:E33	A:A:H195	7.39	No	No	0	6	4
528	A:A:E33	A:A:K197	10.8	No	Yes	0	6	6
529	A:A:L36	A:A:V34	2.98	No	Yes	0	7	5
530	A:A:F196	A:A:V34	9.18	No	Yes	0	7	5
531	A:A:T219	A:A:V34	4.76	No	Yes	0	7	5
532	A:A:V339	A:A:V34	4.81	No	Yes	0	8	5
533	A:A:F199	A:A:K35	4.96	Yes	No	0	5	9
534	A:A:L36	A:A:M198	5.65	No	No	0	7	7
535	A:A:I222	A:A:L36	2.85	No	No	0	7	7
536	A:A:L37	A:A:L39	4.15	No	Yes	1	9	9
537	A:A:F215	A:A:L37	7.31	Yes	No	1	9	9
538	A:A:I221	A:A:L37	2.85	Yes	No	1	8	9
539	A:A:K46	A:A:L38	5.64	No	No	0	9	8
540	A:A:L38	A:A:M198	4.24	No	No	0	8	7
541	A:A:I222	A:A:L38	2.85	No	No	0	7	8
542	A:A:I221	A:A:L39	2.85	Yes	Yes	1	8	9
543	A:A:F223	A:A:L39	2.44	Yes	Yes	1	9	9
544	A:A:I253	A:A:L39	5.71	Yes	Yes	1	8	9
545	A:A:A41	A:A:E245	3.02	No	No	0	7	9
546	A:A:A41	A:A:S246	3.42	No	No	0	7	9
547	A:A:G45	A:A:T48	1.82	No	No	0	9	9
548	A:A:I49	A:A:T48	3.04	No	No	0	7	9
549	A:A:I49	A:A:N269	2.83	No	No	0	7	9
550	A:A:D328	A:A:K51	8.3	No	No	0	9	9
551	A:A:K51	A:A:N331	5.6	No	Yes	0	9	8
552	A:A:F191	A:A:M53	3.73	Yes	No	0	5	8
553	A:A:G183	A:A:T182	3.64	No	No	1	9	7
554	A:A:I184	A:A:V201	4.61	No	No	1	9	9
555	A:A:F215	A:A:I184	2.51	Yes	No	1	9	9
556	A:A:E186	A:A:H188	7.39	Yes	No	1	9	3
557	A:A:E186	A:A:K197	2.7	Yes	Yes	1	9	6
558	A:A:E186	A:A:F199	10.49	Yes	Yes	1	9	5
559	A:A:F189	A:A:T187	2.59	No	No	0	9	6
560	A:A:H188	A:A:K197	13.1	No	Yes	1	3	6
561	A:A:F189	A:A:F196	12.86	No	No	0	9	7
562	A:A:F189	A:A:M198	4.98	No	No	0	9	7
563	A:A:H195	A:A:T190	4.11	No	No	0	4	3
564	A:A:F191	A:A:K192	14.89	Yes	No	17	5	4
565	A:A:F191	A:A:I332	10.05	Yes	No	0	5	7
566	A:A:F191	A:A:F336	8.57	Yes	No	17	5	8
567	A:A:F336	A:A:K192	4.96	No	No	17	8	4
568	A:A:F196	A:A:L194	7.31	No	No	0	7	4
569	A:A:L194	R:R:M139	2.83	No	Yes	0	4	5
570	A:A:L194	R:R:F142	2.44	No	No	0	4	5
571	A:A:F199	A:A:K197	4.96	Yes	Yes	1	5	6
572	A:A:F199	A:A:F215	4.29	Yes	Yes	1	5	9
573	A:A:V201	A:A:W211	6.13	No	Yes	1	9	9
574	A:A:F215	A:A:V201	2.62	Yes	No	1	9	9
575	A:A:Q204	A:A:S206	4.33	Yes	Yes	1	9	8
576	A:A:Q204	A:A:W211	4.38	Yes	Yes	1	9	9
577	A:A:S206	A:A:W211	3.71	Yes	Yes	1	8	9
578	A:A:E207	A:A:K209	12.15	No	No	1	9	8
579	A:A:E207	A:A:K210	2.7	No	Yes	1	9	9
580	A:A:R208	A:A:W211	4	Yes	Yes	1	9	9
581	A:A:I212	A:A:R208	5.01	Yes	Yes	1	8	9
582	A:A:L249	A:A:R208	3.64	Yes	Yes	1	9	9
583	A:A:R208	A:A:S252	2.64	Yes	No	0	9	7
584	A:A:I253	A:A:R208	2.51	Yes	Yes	1	8	9
585	A:A:K209	A:A:K210	4.31	No	Yes	1	8	9
586	A:A:I212	A:A:W211	2.35	Yes	Yes	1	8	9
587	A:A:F215	A:A:W211	4.01	Yes	Yes	1	9	9
588	A:A:I212	A:A:N256	2.83	Yes	No	1	8	8
589	A:A:I212	A:A:W258	2.35	Yes	Yes	1	8	5
590	A:A:F259	A:A:I212	3.77	Yes	Yes	1	9	8
591	A:A:C214	A:A:H213	2.95	Yes	Yes	1	7	8
592	A:A:H213	A:A:W258	11.64	Yes	Yes	1	8	5
593	A:A:F215	A:A:V218	2.62	Yes	No	0	9	9
594	A:A:E216	A:A:W258	7.63	No	Yes	0	7	5
595	A:A:T262	A:A:V218	3.17	Yes	No	0	7	9
596	A:A:I221	A:A:I253	2.94	Yes	Yes	1	8	8
597	A:A:F259	A:A:I221	8.79	Yes	Yes	1	9	8
598	A:A:I221	A:A:T262	4.56	Yes	Yes	1	8	7
599	A:A:F267	A:A:I222	2.51	Yes	No	0	9	7
600	A:A:F223	A:A:V225	2.62	Yes	Yes	0	9	7
601	A:A:F223	A:A:L249	6.09	Yes	Yes	1	9	9
602	A:A:F223	A:A:F250	12.86	Yes	Yes	1	9	9
603	A:A:F223	A:A:L266	2.44	Yes	Yes	1	9	9
604	A:A:L268	A:A:V225	2.98	Yes	Yes	0	8	7
605	A:A:F307	A:A:V225	6.55	Yes	Yes	0	8	7
606	A:A:A226	A:A:D229	3.09	No	No	0	8	8
607	A:A:A226	A:A:K270	4.82	No	No	0	8	9
608	A:A:L227	A:A:L268	2.77	Yes	Yes	1	7	8
609	A:A:F274	A:A:L227	6.09	Yes	Yes	1	9	7
610	A:A:I303	A:A:L227	4.28	Yes	Yes	1	7	7
611	A:A:F323	A:A:L227	2.44	Yes	Yes	1	4	7
612	A:A:K270	A:A:S228	7.65	No	No	0	9	9
613	A:A:L273	A:A:S228	3	Yes	No	1	6	9
614	A:A:K277	A:A:S228	3.06	Yes	No	1	9	9
615	A:A:D229	A:A:R242	13.1	No	Yes	0	8	9
616	A:A:D231	A:A:Y230	16.09	No	Yes	1	9	8
617	A:A:F274	A:A:Y230	9.28	Yes	Yes	1	9	8
618	A:A:K277	A:A:Y230	8.36	Yes	Yes	1	9	8
619	A:A:I278	A:A:Y230	8.46	No	Yes	1	6	8
620	A:A:S281	A:A:Y230	5.09	No	Yes	1	7	8
621	A:A:L283	A:A:Y230	4.69	Yes	Yes	1	7	8
622	A:A:D231	A:A:K277	12.44	No	Yes	1	9	9
623	A:A:D231	A:A:S281	5.89	No	No	1	9	7
624	A:A:L232	A:A:R242	2.43	No	Yes	0	8	9
625	A:A:N241	A:A:V233	10.35	No	No	0	9	5
626	A:A:L234	A:A:R242	8.5	No	Yes	0	8	9
627	A:A:D237	A:A:E236	2.6	No	No	0	8	9
628	A:A:D237	A:A:M240	12.48	No	No	0	8	6
629	A:A:C286	A:A:N241	6.3	No	No	0	6	9
630	A:A:C286	A:A:M243	3.24	No	Yes	1	6	8
631	A:A:M243	A:A:Y287	3.59	Yes	Yes	1	8	7
632	A:A:I303	A:A:M243	4.37	Yes	Yes	1	7	8
633	A:A:F307	A:A:M243	3.73	Yes	Yes	1	8	8
634	A:A:E245	A:A:K248	2.7	No	No	0	9	5
635	A:A:M247	A:A:Y287	3.59	No	Yes	0	6	7
636	A:A:F307	A:A:M247	4.98	Yes	No	0	8	6
637	A:A:I253	A:A:L249	4.28	Yes	Yes	1	8	9
638	A:A:C254	A:A:F250	5.59	Yes	Yes	1	5	9
639	A:A:F250	A:A:I264	2.51	Yes	Yes	1	9	6
640	A:A:F250	A:A:L266	3.65	Yes	Yes	1	9	9
641	A:A:F250	A:A:F307	6.43	Yes	Yes	1	9	8
642	A:A:F250	A:A:L310	2.44	Yes	No	0	9	4
643	A:A:F250	A:A:I319	2.51	Yes	Yes	1	9	5
644	A:A:D251	A:A:N255	6.73	No	No	0	5	8
645	A:A:D251	A:A:L310	2.71	No	No	0	5	4
646	A:A:C254	A:A:N255	3.15	Yes	No	0	5	8
647	A:A:C254	A:A:I264	3.27	Yes	Yes	1	5	6
648	A:A:C254	A:A:N311	4.72	Yes	No	1	5	8
649	A:A:C254	A:A:K317	3.23	Yes	Yes	1	5	7
650	A:A:K312	A:A:N255	4.2	No	No	0	5	8
651	A:A:N256	A:A:W258	5.65	No	Yes	1	8	5
652	A:A:F259	A:A:N256	4.83	Yes	No	1	9	8
653	A:A:K257	A:A:W258	16.24	No	Yes	0	4	5
654	A:A:F259	A:A:W258	2	Yes	Yes	1	9	5
655	A:A:F259	A:A:T262	3.89	Yes	Yes	1	9	7
656	A:A:S263	A:A:Y320	5.09	No	Yes	11	7	7
657	A:A:S263	A:A:T342	6.4	No	No	11	7	7
658	A:A:I264	A:A:K317	7.27	Yes	Yes	1	6	7
659	A:A:I264	A:A:I319	2.94	Yes	Yes	1	6	5
660	A:A:F267	A:A:I265	2.51	Yes	No	0	9	8
661	A:A:F334	A:A:I265	2.51	Yes	No	0	3	8
662	A:A:A338	A:A:I265	3.25	No	No	0	6	8
663	A:A:L266	A:A:L268	4.15	Yes	Yes	1	9	8
664	A:A:F307	A:A:L266	3.65	Yes	Yes	1	8	9
665	A:A:L266	A:A:T321	8.84	Yes	Yes	1	9	5
666	A:A:F267	A:A:N269	3.62	Yes	No	10	9	9
667	A:A:F267	A:A:H322	2.26	Yes	Yes	10	9	9
668	A:A:F267	A:A:T324	5.19	Yes	No	10	9	9
669	A:A:F267	A:A:N331	3.62	Yes	Yes	10	9	8
670	A:A:F267	A:A:V335	2.62	Yes	No	0	9	8
671	A:A:L268	A:A:T321	2.95	Yes	Yes	1	8	5
672	A:A:F323	A:A:L268	4.87	Yes	Yes	1	4	8
673	A:A:N269	A:A:T324	8.77	No	No	10	9	9
674	A:A:K271	A:A:Y296	7.17	No	Yes	0	5	4
675	A:A:C325	A:A:K271	4.85	No	No	0	7	5
676	A:A:E276	A:A:L273	2.65	No	Yes	0	5	6
677	A:A:K277	A:A:L273	2.82	Yes	Yes	1	9	6
678	A:A:F274	A:A:I278	6.28	Yes	No	1	9	6
679	A:A:F274	A:A:Y296	2.06	Yes	Yes	1	9	4
680	A:A:E275	A:A:Y296	15.71	No	Yes	0	5	4
681	A:A:K277	A:A:K280	5.75	Yes	No	0	9	1
682	A:A:I278	A:A:N294	4.25	No	No	0	6	3
683	A:A:P282	A:A:T284	5.25	No	No	0	5	4
684	A:A:N294	A:A:P282	3.26	No	No	0	3	5
685	A:A:L283	A:A:Y287	7.03	Yes	Yes	1	7	7
686	A:A:L283	A:A:Y290	9.38	Yes	Yes	1	7	7
687	A:A:L283	A:A:Y302	4.69	Yes	Yes	1	7	6
688	A:A:I303	A:A:L283	4.28	Yes	Yes	1	7	7
689	A:A:C286	A:A:Y287	9.41	No	Yes	1	6	7
690	A:A:Y287	A:A:Y302	5.96	Yes	Yes	1	7	6
691	A:A:I303	A:A:Y287	6.04	Yes	Yes	1	7	7
692	A:A:Q306	A:A:Y287	6.76	No	Yes	1	5	7
693	A:A:E289	A:A:P288	6.29	No	No	0	6	5
694	A:A:G292	A:A:Y290	4.35	No	Yes	0	7	7
695	A:A:E298	A:A:Y290	7.86	No	Yes	0	4	7
696	A:A:Y290	A:A:Y302	13.9	Yes	Yes	1	7	6
697	A:A:S293	A:A:T295	6.4	No	No	0	3	5
698	A:A:E298	A:A:S293	7.19	No	No	0	4	3
699	A:A:A300	A:A:Y296	2.67	No	Yes	1	5	4
700	A:A:F323	A:A:Y296	5.16	Yes	Yes	1	4	4
701	A:A:A300	A:A:F323	2.77	No	Yes	1	5	4
702	A:A:Q306	A:A:Y302	13.53	No	Yes	1	5	6
703	A:A:F307	A:A:I303	2.51	Yes	Yes	1	8	7
704	A:A:E308	A:A:Q304	7.65	No	No	1	3	5
705	A:A:Q304	A:A:T321	11.34	No	Yes	1	5	5
706	A:A:D309	A:A:Q306	2.61	No	No	0	4	5
707	A:A:E308	A:A:I319	2.73	No	Yes	1	3	5
708	A:A:E308	A:A:T321	5.64	No	Yes	1	3	5
709	A:A:D309	A:A:L310	2.71	No	No	0	4	4
710	A:A:K317	A:A:N311	4.2	Yes	No	1	7	8
711	A:A:I319	A:A:N311	4.25	Yes	No	1	5	8
712	A:A:D315	A:A:R313	13.1	No	No	1	3	4
713	A:A:R313	A:A:T316	2.59	No	No	1	4	3
714	A:A:E318	A:A:K314	4.05	No	No	0	4	3
715	A:A:D315	A:A:T316	5.78	No	No	1	3	3
716	A:A:I319	A:A:K317	2.91	Yes	Yes	1	5	7
717	A:A:E318	R:R:Q230	8.92	No	Yes	0	4	3
718	A:A:F334	A:A:Y320	2.06	Yes	Yes	0	3	7
719	A:A:A338	A:A:Y320	5.34	No	Yes	0	6	7
720	A:A:D341	A:A:Y320	6.9	Yes	Yes	11	8	7
721	A:A:T342	A:A:Y320	3.75	No	Yes	11	7	7
722	A:A:Y320	R:R:L229	2.34	Yes	No	11	7	2
723	A:A:Y320	R:R:Q230	11.27	Yes	Yes	0	7	3
724	A:A:E330	A:A:H322	2.46	No	Yes	0	4	9
725	A:A:H322	A:A:N331	2.55	Yes	Yes	10	9	8
726	A:A:F334	A:A:H322	20.36	Yes	Yes	0	3	9
727	A:A:N331	A:A:T324	4.39	Yes	No	10	8	9
728	A:A:T327	A:A:T329	6.28	No	No	0	8	9
729	A:A:E330	A:A:T327	7.06	No	No	0	4	8
730	A:A:I332	A:A:V335	3.07	No	No	0	7	8
731	A:A:F334	A:A:R333	2.14	Yes	No	0	3	5
732	A:A:F336	R:R:M139	3.73	No	Yes	0	8	5
733	A:A:I343	A:A:V339	3.07	No	No	0	7	8
734	A:A:K340	R:R:P138	3.35	No	No	0	6	8
735	A:A:K340	R:R:M139	7.2	No	Yes	0	6	5
736	A:A:D341	A:A:Q345	5.22	Yes	No	0	8	5
737	A:A:D341	R:R:L229	2.71	Yes	No	11	8	2
738	A:A:D341	R:R:K236	2.77	Yes	Yes	0	8	5
739	A:A:I343	A:A:N347	2.83	No	No	0	7	8
740	A:A:I343	R:R:M139	2.92	No	Yes	0	7	5
741	A:A:L344	R:R:P138	3.28	No	No	0	6	8
742	A:A:L344	R:R:K236	2.82	No	Yes	0	6	5
743	A:A:Q345	R:R:S233	2.89	No	No	0	5	2
744	A:A:N347	R:R:V134	7.39	No	Yes	2	8	8
745	A:A:N347	R:R:H145	5.1	No	No	2	8	7
746	A:A:L348	A:A:L353	2.77	Yes	Yes	2	9	7
747	A:A:L348	R:R:I135	2.85	Yes	No	0	9	8
748	A:A:K349	A:A:V354	4.55	No	Yes	0	5	8
749	A:A:K349	R:R:D307	6.91	No	No	0	5	4
750	A:A:E350	A:A:Y351	3.37	No	Yes	0	4	4
751	A:A:E350	R:R:K66	10.8	No	No	0	4	7
752	A:A:Y351	R:R:S67	2.54	Yes	No	0	4	6
753	A:A:Y351	R:R:S68	5.09	Yes	No	2	4	8
754	A:A:Y351	R:R:F127	3.09	Yes	Yes	2	4	9
755	A:A:Y351	R:R:R131	2.06	Yes	Yes	2	4	9
756	A:A:Y351	R:R:V134	13.88	Yes	Yes	2	4	8
757	A:A:N352	R:R:M72	2.8	No	Yes	0	7	8
758	A:A:N352	R:R:S306	8.94	No	No	0	7	8
759	A:A:L353	R:R:R131	10.93	Yes	Yes	2	7	9
760	A:A:L353	R:R:T243	2.95	Yes	No	0	7	8
761	A:A:V354	R:R:L235	11.92	Yes	No	0	8	4
762	A:A:V354	R:R:K238	6.07	Yes	No	0	8	6
763	G:G:I9	G:G:R13	5.01	No	No	0	2	6
764	G:G:E17	G:G:K14	2.7	No	No	0	6	4
765	G:G:K20	G:G:V16	3.04	No	Yes	0	6	7
766	G:G:E17	G:G:K20	2.7	No	No	0	6	6
767	G:G:E22	G:G:Q18	7.65	No	No	0	9	9
768	G:G:I25	G:G:R27	11.27	No	Yes	4	2	8
769	G:G:I28	G:G:K32	5.82	No	No	0	4	5
770	G:G:D36	G:G:K32	5.53	No	No	0	5	5
771	G:G:H44	G:G:Y40	13.07	No	Yes	0	6	6
772	G:G:A43	G:G:H44	2.93	No	No	0	4	6
773	G:G:E47	G:G:H44	8.62	No	No	0	3	6
774	G:G:D48	G:G:P49	3.22	Yes	Yes	0	9	7
775	G:G:D48	G:G:L51	6.79	Yes	Yes	0	9	6
776	G:G:L51	G:G:T52	2.95	Yes	No	0	6	4
777	G:G:P55	G:G:V54	3.53	No	No	0	5	6
778	G:G:E58	G:G:P55	9.43	No	No	0	5	5
779	G:G:E58	G:G:S57	2.87	No	No	0	5	6
780	G:G:N59	G:G:P60	4.89	No	No	0	9	9
781	R:R:C24	R:R:C274	7.28	No	No	18	9	8
782	R:R:C24	R:R:E277	3.04	No	No	18	9	3
783	R:R:E27	R:R:T25	5.64	No	No	0	2	5
784	R:R:E27	R:R:N278	9.2	No	No	0	2	3
785	R:R:H281	R:R:N28	5.1	Yes	No	0	4	3
786	R:R:I29	R:R:P30	3.39	No	No	0	3	1
787	R:R:L31	R:R:Y35	4.69	No	No	0	3	5
788	R:R:K32	R:R:L36	4.23	Yes	Yes	2	3	6
789	R:R:K32	R:R:Y93	3.58	Yes	Yes	2	3	5
790	R:R:H281	R:R:K32	3.93	Yes	Yes	2	4	3
791	R:R:I285	R:R:K32	4.36	No	Yes	2	5	3
792	R:R:H34	R:R:Y35	10.89	No	No	0	2	5
793	R:R:L36	R:R:Y40	7.03	Yes	No	0	6	7
794	R:R:L36	R:R:Y93	4.69	Yes	Yes	2	6	5
795	R:R:I285	R:R:L36	4.28	No	Yes	2	5	6
796	R:R:I39	R:R:I43	2.94	No	No	0	5	7
797	R:R:L86	R:R:Y40	2.34	No	No	0	8	7
798	R:R:I90	R:R:Y40	2.42	No	No	0	7	7
799	R:R:F296	R:R:I43	6.28	Yes	No	0	8	7
800	R:R:F44	R:R:F48	7.5	No	Yes	0	7	6
801	R:R:F44	R:R:L86	3.65	No	No	0	7	8
802	R:R:F44	R:R:P87	7.22	No	No	0	7	9
803	R:R:F296	R:R:V46	5.24	Yes	No	0	8	6
804	R:R:F48	R:R:P49	2.89	Yes	No	0	6	4
805	R:R:F48	R:R:L80	9.74	Yes	No	0	6	7
806	R:R:D79	R:R:N51	6.73	No	No	0	9	9
807	R:R:L80	R:R:N51	2.75	No	No	0	7	9
808	R:R:L299	R:R:N51	4.12	No	No	0	9	9
809	R:R:V54	R:R:Y58	5.05	Yes	Yes	0	8	7
810	R:R:V303	R:R:V54	4.81	No	Yes	12	6	8
811	R:R:F309	R:R:V54	2.62	Yes	Yes	12	8	8
812	R:R:I55	R:R:I59	2.94	No	No	0	7	4
813	R:R:A76	R:R:I55	3.25	No	No	0	9	7
814	R:R:F309	R:R:T57	7.78	Yes	Yes	12	8	7
815	R:R:T57	R:R:V313	3.17	Yes	No	12	7	6
816	R:R:M62	R:R:Y58	2.39	No	Yes	0	6	7
817	R:R:T69	R:R:Y58	3.75	No	Yes	0	7	7
818	R:R:M72	R:R:Y58	5.99	Yes	Yes	0	8	7
819	R:R:L73	R:R:Y58	3.52	No	Yes	0	5	7
820	R:R:F60	R:R:I59	2.51	No	No	0	4	4
821	R:R:K61	R:R:T316	6.01	No	No	0	5	5
822	R:R:L73	R:R:W65	4.56	No	No	0	5	6
823	R:R:K66	R:R:T69	3	No	No	0	7	7
824	R:R:F130	R:R:S67	2.64	Yes	No	0	8	6
825	R:R:F127	R:R:S68	2.64	Yes	No	2	9	8
826	R:R:I70	R:R:T147	3.04	No	No	0	7	2
827	R:R:A150	R:R:I70	4.87	No	No	0	7	7
828	R:R:C126	R:R:I71	3.27	No	No	2	7	7
829	R:R:F127	R:R:I71	6.28	Yes	No	2	9	7
830	R:R:F130	R:R:I71	6.28	Yes	No	2	8	7
831	R:R:F127	R:R:M72	6.22	Yes	Yes	2	9	8
832	R:R:M72	R:R:Y302	4.79	Yes	Yes	2	8	9
833	R:R:C77	R:R:L73	3.17	No	No	0	5	5
834	R:R:F123	R:R:N74	9.67	Yes	No	2	8	9
835	R:R:C154	R:R:N74	9.45	No	No	2	7	9
836	R:R:N74	R:R:W158	4.52	No	Yes	2	9	9
837	R:R:F123	R:R:L75	2.44	Yes	No	2	8	9
838	R:R:L124	R:R:L75	2.77	Yes	No	2	8	9
839	R:R:L75	R:R:N298	2.75	No	Yes	2	9	9
840	R:R:N116	R:R:T78	5.85	Yes	Yes	2	8	8
841	R:R:S119	R:R:T78	6.4	Yes	Yes	2	7	8
842	R:R:T78	R:R:W158	6.06	Yes	Yes	2	8	9
843	R:R:D79	R:R:T295	7.23	No	No	0	9	9
844	R:R:D79	R:R:N298	4.04	No	Yes	0	9	9
845	R:R:L81	R:R:N116	6.87	No	Yes	0	7	8
846	R:R:F113	R:R:Y82	12.38	No	No	0	6	7
847	R:R:N116	R:R:Y82	4.65	Yes	No	0	8	7
848	R:R:T295	R:R:Y82	2.5	No	No	0	9	7
849	R:R:L83	R:R:L86	2.77	No	No	0	6	8
850	R:R:I109	R:R:S85	4.64	Yes	No	0	5	7
851	R:R:F88	R:R:W99	3.01	Yes	Yes	2	6	9
852	R:R:F101	R:R:F88	8.57	Yes	Yes	2	7	6
853	R:R:F88	R:R:M105	2.49	Yes	Yes	2	6	6
854	R:R:F88	R:R:I109	10.05	Yes	Yes	2	6	5
855	R:R:L89	R:R:Y93	3.52	No	Yes	2	6	5
856	R:R:L89	R:R:R110	6.07	No	Yes	2	6	5
857	R:R:H91	R:R:S95	8.37	No	No	0	5	3
858	R:R:H91	R:R:I100	5.3	No	No	0	5	1
859	R:R:F101	R:R:H91	10.18	Yes	No	0	7	5
860	R:R:Y92	R:R:Y93	9.93	Yes	Yes	2	5	5
861	R:R:E97	R:R:Y92	12.35	Yes	Yes	2	4	5
862	R:R:W99	R:R:Y92	5.79	Yes	Yes	2	9	5
863	R:R:C183	R:R:Y92	2.69	Yes	Yes	2	9	5
864	R:R:R110	R:R:Y93	2.06	Yes	Yes	2	5	5
865	R:R:E97	R:R:N98	2.63	Yes	No	2	4	4
866	R:R:E97	R:R:R177	4.65	Yes	No	2	4	3
867	R:R:E97	R:R:R180	10.47	Yes	Yes	2	4	2
868	R:R:A182	R:R:E97	3.02	No	Yes	2	3	4
869	R:R:N98	R:R:R180	6.03	No	Yes	2	4	2
870	R:R:F101	R:R:W99	13.03	Yes	Yes	2	7	9
871	R:R:M105	R:R:W99	3.49	Yes	Yes	2	6	9
872	R:R:C106	R:R:W99	6.53	No	Yes	2	9	9
873	R:R:I109	R:R:W99	4.7	Yes	Yes	2	5	9
874	R:R:C183	R:R:W99	6.53	Yes	Yes	2	9	9
875	R:R:F101	R:R:M105	2.49	Yes	Yes	2	7	6
876	R:R:D103	R:R:S174	4.42	No	No	0	3	5
877	R:R:F104	R:R:F108	5.36	No	No	0	3	5
878	R:R:I109	R:R:M105	4.37	Yes	Yes	2	5	6
879	R:R:C106	R:R:C183	7.28	No	Yes	2	9	9
880	R:R:I172	R:R:K107	2.91	No	No	0	4	7
881	R:R:K107	R:R:S174	3.06	No	No	0	7	5
882	R:R:F108	R:R:I109	2.51	No	Yes	0	5	5
883	R:R:C183	R:R:R110	4.18	Yes	Yes	2	9	5
884	R:R:D185	R:R:R110	4.76	Yes	Yes	2	5	5
885	R:R:R110	R:R:R288	3.2	Yes	Yes	2	5	6
886	R:R:F111	R:R:F115	5.36	No	Yes	2	5	5
887	R:R:F111	R:R:V165	6.55	No	No	2	5	7
888	R:R:F111	R:R:T169	5.19	No	No	0	5	4
889	R:R:N116	R:R:S112	4.47	Yes	No	0	8	4
890	R:R:F113	R:R:H114	7.92	No	Yes	0	6	6
891	R:R:H114	R:R:Y118	3.27	Yes	Yes	2	6	7
892	R:R:H114	R:R:M168	9.19	Yes	Yes	2	6	4
893	R:R:H114	R:R:R261	2.26	Yes	Yes	2	6	5
894	R:R:H114	R:R:R288	2.26	Yes	Yes	2	6	6
895	R:R:F115	R:R:N116	3.62	Yes	Yes	2	5	8
896	R:R:F115	R:R:W158	5.01	Yes	Yes	2	5	9
897	R:R:F115	R:R:S161	3.96	Yes	No	0	5	8
898	R:R:F115	R:R:L162	4.87	Yes	No	0	5	4
899	R:R:F115	R:R:V165	6.55	Yes	No	2	5	7
900	R:R:N116	R:R:S119	2.98	Yes	Yes	2	8	7
901	R:R:L117	R:R:Y118	4.69	No	Yes	0	8	7
902	R:R:F254	R:R:L117	3.65	Yes	No	0	8	8
903	R:R:F257	R:R:L117	2.44	Yes	No	0	7	8
904	R:R:L202	R:R:Y118	5.86	No	Yes	2	5	7
905	R:R:T206	R:R:Y118	7.49	Yes	Yes	2	5	7
906	R:R:H258	R:R:Y118	6.53	Yes	Yes	0	8	7
907	R:R:R261	R:R:Y118	5.14	Yes	Yes	2	5	7
908	R:R:S119	R:R:W158	4.94	Yes	Yes	2	7	9
909	R:R:S119	R:R:S161	3.26	Yes	No	0	7	8
910	R:R:I121	R:R:P210	3.39	No	No	0	8	8
911	R:R:F254	R:R:I121	13.82	Yes	No	0	8	8
912	R:R:L122	R:R:V157	4.47	Yes	No	0	6	7
913	R:R:I160	R:R:L122	2.85	No	Yes	2	4	6
914	R:R:L122	R:R:S161	3	Yes	No	0	6	8
915	R:R:L122	R:R:T206	2.95	Yes	Yes	2	6	5
916	R:R:L122	W:W:?1	5.26	Yes	Yes	2	6	0
917	R:R:C154	R:R:F123	5.59	No	Yes	2	7	8
918	R:R:F123	R:R:V157	10.49	Yes	No	0	8	7
919	R:R:F123	R:R:W158	10.02	Yes	Yes	2	8	9
920	R:R:F250	R:R:L124	3.65	No	Yes	0	9	8
921	R:R:L124	R:R:N298	8.24	Yes	Yes	2	8	9
922	R:R:L124	R:R:Y302	4.69	Yes	Yes	2	8	9
923	R:R:P210	R:R:T125	6.99	No	Yes	0	8	7
924	R:R:I213	R:R:T125	3.04	No	Yes	0	7	7
925	R:R:T125	R:R:V214	3.17	Yes	No	0	7	8
926	R:R:T125	W:W:?1	1.87	Yes	Yes	0	7	0
927	R:R:C126	R:R:F130	4.19	No	Yes	2	7	8
928	R:R:F127	R:R:R131	11.76	Yes	Yes	2	9	9
929	R:R:F127	R:R:Y302	4.13	Yes	Yes	2	9	9
930	R:R:S128	R:R:V214	4.85	No	No	2	9	8
931	R:R:C217	R:R:S128	3.44	No	No	0	7	9
932	R:R:S128	R:R:Y218	6.36	No	Yes	2	9	8
933	R:R:I129	R:R:I213	2.94	No	No	0	6	7
934	R:R:F130	R:R:I144	10.05	Yes	No	2	8	4
935	R:R:A153	R:R:F130	2.77	No	Yes	0	6	8
936	R:R:F130	W:W:?1	3.09	Yes	Yes	2	8	0
937	R:R:R131	R:R:Y218	6.17	Yes	Yes	2	9	8
938	R:R:L246	R:R:R131	2.43	Yes	Yes	2	8	9
939	R:R:R131	R:R:Y302	6.17	Yes	Yes	2	9	9
940	R:R:I136	R:R:Y132	14.51	Yes	No	19	8	8
941	R:R:C217	R:R:Y132	9.41	No	No	0	7	8
942	R:R:T220	R:R:Y132	6.24	No	No	19	3	8
943	R:R:C133	R:R:I144	4.91	No	No	2	5	4
944	R:R:C133	W:W:?1	2.01	No	Yes	2	5	0
945	R:R:I135	R:R:V134	3.07	No	Yes	0	8	8
946	R:R:H145	R:R:V134	4.15	No	Yes	2	7	8
947	R:R:H137	R:R:I136	7.95	No	Yes	0	7	8
948	R:R:I136	R:R:T220	3.04	Yes	No	19	8	3
949	R:R:I136	R:R:T224	4.56	Yes	No	0	8	5
950	R:R:H137	R:R:S140	4.18	No	No	0	7	5
951	R:R:C141	W:W:?1	6.03	No	Yes	0	6	0
952	R:R:K146	R:R:S143	3.06	No	No	0	6	4
953	R:R:I144	W:W:?1	5.43	No	Yes	2	4	0
954	R:R:R148	W:W:?1	6.16	No	Yes	0	4	0
955	R:R:C149	W:W:?1	16.09	No	Yes	0	3	0
956	R:R:V152	W:W:?1	16.99	No	Yes	0	2	0
957	R:R:I160	R:R:V156	3.07	No	No	0	4	4
958	R:R:I160	W:W:?1	3.62	No	Yes	2	4	0
959	R:R:I166	R:R:P167	3.39	No	No	0	4	8
960	R:R:P167	R:R:Y198	6.95	No	Yes	0	8	5
961	R:R:I172	R:R:M168	2.92	No	Yes	2	4	4
962	R:R:L186	R:R:M168	7.07	No	Yes	2	3	4
963	R:R:M168	R:R:Y198	4.79	Yes	Yes	2	4	5
964	R:R:F170	R:R:L171	4.87	No	No	0	4	5
965	R:R:E191	R:R:L171	5.3	Yes	No	0	3	5
966	R:R:L171	R:R:T194	2.95	No	No	0	5	3
967	R:R:I172	R:R:L186	2.85	No	No	2	4	3
968	R:R:S189	R:R:T173	6.4	No	Yes	13	4	4
969	R:R:D190	R:R:T173	7.23	No	Yes	13	3	4
970	R:R:E191	R:R:T173	4.23	Yes	Yes	13	3	4
971	R:R:N176	R:R:S181	2.98	No	No	0	1	5
972	R:R:R177	R:R:R180	18.13	No	Yes	2	3	2
973	R:R:A182	R:R:R177	4.15	No	No	2	3	3
974	R:R:N179	R:R:T178	4.39	No	No	0	5	1
975	R:R:N179	R:R:R180	10.85	No	Yes	0	5	2
976	R:R:A182	R:R:L184	4.73	No	No	0	3	4
977	R:R:L184	R:R:S188	7.51	No	No	0	4	5
978	R:R:D185	R:R:T187	7.23	Yes	Yes	2	5	4
979	R:R:D185	R:R:S188	4.42	Yes	No	0	5	5
980	R:R:D185	R:R:Y284	3.45	Yes	Yes	2	5	5
981	R:R:D185	R:R:R288	5.96	Yes	Yes	2	5	6
982	R:R:L186	R:R:Y198	2.34	No	Yes	2	3	5
983	R:R:R261	R:R:T187	2.59	Yes	Yes	2	5	4
984	R:R:R264	R:R:T187	11.64	No	Yes	0	5	4
985	R:R:I265	R:R:T187	3.04	No	Yes	0	5	4
986	R:R:T187	R:R:Y284	11.24	Yes	Yes	2	4	5
987	R:R:E191	R:R:S189	4.31	Yes	No	13	3	4
988	R:R:I195	R:R:S189	3.1	No	No	13	4	4
989	R:R:D190	R:R:E191	12.99	No	Yes	13	3	3
990	R:R:E191	R:R:I195	2.73	Yes	No	13	3	4
991	R:R:L192	R:R:R268	9.72	No	No	0	2	4
992	R:R:L192	R:R:L269	11.07	No	No	0	2	2
993	R:R:N193	R:R:W197	5.65	No	No	0	1	3
994	R:R:I195	R:R:I265	2.94	No	No	0	4	5
995	R:R:K196	R:R:W197	5.8	Yes	No	0	3	3
996	R:R:E266	R:R:K196	8.1	No	Yes	0	4	3
997	R:R:K196	R:R:L269	2.82	Yes	No	0	3	2
998	R:R:L202	R:R:Y198	4.69	No	Yes	2	5	5
999	R:R:N199	R:R:T203	2.92	Yes	No	0	6	4
1000	R:R:N199	R:R:R261	9.64	Yes	Yes	0	6	5
1001	R:R:I265	R:R:N199	5.66	No	Yes	0	5	6
1002	R:R:L202	R:R:T206	2.95	No	Yes	2	5	5
1003	R:R:H258	R:R:T203	4.11	Yes	No	0	8	4
1004	R:R:T205	R:R:T206	4.71	No	Yes	0	4	5
1005	R:R:T205	W:W:?1	5.6	No	Yes	0	4	0
1006	R:R:F207	R:R:L211	6.09	Yes	No	0	8	6
1007	R:R:F207	R:R:F254	3.22	Yes	Yes	0	8	8
1008	R:R:F207	R:R:L255	3.65	Yes	No	0	8	5
1009	R:R:F207	R:R:H258	22.63	Yes	Yes	0	8	8
1010	R:R:L209	W:W:?1	3.51	No	Yes	0	5	0
1011	R:R:F250	R:R:L211	3.65	No	No	0	9	6
1012	R:R:L211	R:R:Y251	10.55	No	No	0	6	6
1013	R:R:L216	R:R:V212	2.98	No	No	0	4	3
1014	R:R:V214	R:R:Y218	2.52	No	Yes	2	8	8
1015	R:R:T215	R:R:Y251	6.24	No	No	0	4	6
1016	R:R:I221	R:R:Y218	2.42	No	Yes	0	8	8
1017	R:R:T243	R:R:Y218	4.99	No	Yes	0	8	8
1018	R:R:L246	R:R:Y218	2.34	Yes	Yes	2	8	8
1019	R:R:L247	R:R:Y218	4.69	No	Yes	0	8	8
1020	R:R:I221	R:R:L225	2.85	No	No	0	8	8
1021	R:R:I222	R:R:R240	3.76	No	No	0	4	6
1022	R:R:I222	R:R:T243	6.08	No	No	0	4	8
1023	R:R:H223	R:R:H227	13.14	No	No	0	2	4
1024	R:R:K236	R:R:L225	2.82	Yes	No	0	5	8
1025	R:R:H227	R:R:T226	5.48	No	No	0	4	4
1026	R:R:R240	R:R:T226	2.59	No	No	0	6	4
1027	R:R:D232	R:R:Q230	3.92	No	Yes	0	5	3
1028	R:R:Q230	R:R:S233	5.78	Yes	No	0	3	2
1029	R:R:K236	R:R:S233	3.06	Yes	No	0	5	2
1030	R:R:Q237	R:R:R241	5.84	No	No	0	5	5
1031	R:R:I244	R:R:R240	2.51	No	No	0	5	6
1032	R:R:L242	R:R:V305	4.47	No	No	0	8	6
1033	R:R:L245	R:R:L301	2.77	No	Yes	0	5	7
1034	R:R:L246	R:R:L301	4.15	Yes	Yes	2	8	7
1035	R:R:L246	R:R:Y302	10.55	Yes	Yes	2	8	9
1036	R:R:L247	R:R:Y251	2.34	No	No	0	8	6
1037	R:R:F250	R:R:F254	9.65	No	Yes	0	9	8
1038	R:R:C253	R:R:N294	11.02	No	No	0	8	9
1039	R:R:F254	R:R:N294	10.87	Yes	No	0	8	9
1040	R:R:I259	R:R:L255	5.71	No	No	0	6	5
1041	R:R:F257	R:R:H258	4.53	Yes	Yes	0	7	8
1042	R:R:F257	R:R:R261	5.34	Yes	Yes	2	7	5
1043	R:R:F257	R:R:Y284	7.22	Yes	Yes	2	7	5
1044	R:R:F257	R:R:S287	3.96	Yes	No	2	7	7
1045	R:R:F257	R:R:R288	2.14	Yes	Yes	2	7	6
1046	R:R:A291	R:R:F257	2.77	No	Yes	0	8	7
1047	R:R:A283	R:R:L260	4.73	No	No	0	5	5
1048	R:R:L260	R:R:S287	4.5	No	No	0	5	7
1049	R:R:R261	R:R:Y284	5.14	Yes	Yes	2	5	5
1050	R:R:I263	R:R:I280	2.94	No	No	0	5	5
1051	R:R:R264	R:R:R268	7.46	No	No	0	5	4
1052	R:R:H281	R:R:R264	15.8	Yes	No	0	4	5
1053	R:R:I280	R:R:S267	4.64	No	No	0	5	5
1054	R:R:I272	R:R:L270	4.28	Yes	No	0	1	3
1055	R:R:I272	R:R:I276	2.94	Yes	No	0	1	3
1056	R:R:E277	R:R:I272	8.2	No	Yes	0	3	1
1057	R:R:S273	R:R:S275	4.89	No	No	0	4	1
1058	R:R:C274	R:R:E277	6.08	No	No	18	8	3
1059	R:R:I276	R:R:Q279	4.12	No	No	0	3	3
1060	R:R:H281	R:R:I285	7.95	Yes	No	2	4	5
1061	R:R:S287	R:R:Y284	2.54	No	Yes	2	7	5
1062	R:R:R288	R:R:Y284	12.35	Yes	Yes	2	6	5
1063	R:R:P289	R:R:R288	2.88	No	Yes	0	6	6
1064	R:R:F296	R:R:L293	4.87	Yes	No	0	8	5
1065	R:R:N294	R:R:N298	6.81	No	Yes	0	9	9
1066	R:R:N298	R:R:Y302	3.49	Yes	Yes	2	9	9
1067	R:R:L301	R:R:Y302	2.34	Yes	Yes	2	7	9
1068	R:R:F309	R:R:V303	9.18	Yes	No	12	8	6
1069	R:R:D307	R:R:Q310	5.22	No	No	0	4	7
1070	R:R:D307	R:R:Q311	5.22	No	No	0	4	5
1071	R:R:F309	R:R:V313	5.24	Yes	No	12	8	6
1072	R:R:C319	R:R:R318	5.57	No	No	0	9	4
1073	G:G:P49	G:G:V54	1.77	Yes	No	0	7	6
1074	R:R:P37	R:R:V38	1.77	No	No	0	5	5
1075	B:B:G202	B:B:I229	1.76	No	Yes	0	6	7
1076	R:R:G41	R:R:I90	1.76	No	No	0	3	7
1077	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1078	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1079	R:R:G96	R:R:M33	1.75	No	No	0	3	4
1080	A:A:G40	A:A:K46	1.74	No	No	0	9	9
1081	A:A:C224	A:A:S44	1.72	No	No	0	7	9
1082	A:A:G27	B:B:L55	1.71	No	No	0	5	6
1083	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
1084	A:A:G40	A:A:L39	1.71	No	Yes	0	9	9
1085	A:A:G40	A:A:L249	1.71	No	Yes	0	9	9
1086	A:A:A226	A:A:S44	1.71	No	No	0	8	9
1087	A:A:A220	A:A:S263	1.71	No	No	0	8	7
1088	R:R:G47	R:R:L83	1.71	No	No	0	8	6
1089	R:R:A150	R:R:S67	1.71	No	No	0	7	6
1090	B:B:A11	G:G:V16	1.7	No	Yes	0	5	7
1091	R:R:A76	R:R:V54	1.7	No	Yes	0	9	8
1092	A:A:T316	R:R:C234	1.69	No	No	0	3	4
1093	R:R:I90	R:R:P37	1.69	No	No	0	7	5
1094	R:R:I39	R:R:P289	1.69	No	No	0	5	6
1095	B:B:D66	B:B:G64	1.68	No	No	0	8	5
1096	B:B:D186	B:B:G185	1.68	Yes	No	0	9	5
1097	A:A:D26	A:A:G27	1.68	No	No	0	5	5
1098	A:A:D200	A:A:G202	1.68	No	No	0	9	9
1099	R:R:A312	R:R:T57	1.68	No	Yes	0	5	7
1100	R:R:A164	R:R:T206	1.68	No	Yes	0	4	5
1101	B:B:K301	B:B:P39	1.67	Yes	No	0	5	1
1102	A:A:E43	A:A:G45	1.64	No	No	0	9	9
1103	R:R:L255	R:R:P256	1.64	No	No	0	5	9
1104	A:A:I19	B:B:A92	1.62	Yes	No	0	9	6
1105	B:B:S191	B:B:V200	1.62	No	Yes	0	8	6
1106	B:B:A248	B:B:I269	1.62	No	No	0	5	4
1107	A:A:S246	A:A:V225	1.62	No	Yes	0	9	7
1108	R:R:A292	R:R:I43	1.62	No	No	0	7	7
1109	R:R:S322	R:R:V321	1.62	No	No	0	4	3
1110	B:B:D38	B:B:P39	1.61	No	No	0	1	1
1111	G:G:A45	G:G:K46	1.61	No	No	0	4	1
1112	B:B:S207	B:B:T223	1.6	Yes	No	0	5	2
1113	R:R:S120	R:R:T78	1.6	No	Yes	0	9	8
1114	R:R:T57	R:R:V53	1.59	Yes	No	0	7	6
1115	R:R:G228	R:R:H227	1.59	No	No	0	6	4
1116	B:B:L14	G:G:A23	1.58	No	No	0	8	8
1117	A:A:A299	A:A:L283	1.58	No	Yes	0	7	7
1118	A:A:L348	R:R:A239	1.58	Yes	No	2	9	7
1119	A:A:L353	R:R:A239	1.58	Yes	No	2	7	7
1120	R:R:A239	R:R:L225	1.58	No	No	0	7	8
1121	R:R:A249	R:R:L301	1.58	No	Yes	0	6	7
1122	R:R:T173	R:R:T175	1.57	Yes	No	0	4	3
1123	R:R:T215	R:R:T219	1.57	No	No	0	4	4
1124	A:A:A12	B:B:N88	1.56	No	Yes	0	4	7
1125	A:A:C305	A:A:D309	1.56	No	No	0	3	4
1126	A:A:I285	A:A:S281	1.55	No	No	0	3	7
1127	R:R:I272	R:R:S267	1.55	Yes	No	0	1	5
1128	G:G:A35	G:G:D36	1.54	No	No	0	2	5
1129	R:R:I42	R:R:V38	1.54	No	No	0	5	5
1130	R:R:I42	R:R:V46	1.54	No	No	0	5	6
1131	R:R:I70	R:R:V151	1.54	No	No	0	7	4
1132	R:R:I159	R:R:V163	1.54	No	No	0	4	4
1133	B:B:C25	B:B:Q259	1.53	No	Yes	0	3	6
1134	B:B:M262	B:B:S31	1.53	Yes	No	0	4	1
1135	B:B:A21	B:B:Q17	1.52	No	No	0	4	4
1136	B:B:Q17	G:G:A23	1.52	No	No	0	4	8
1137	B:B:A257	B:B:Q259	1.52	No	Yes	0	7	6
1138	R:R:I201	R:R:T205	1.52	No	No	0	4	4
1139	R:R:F296	R:R:G297	1.51	Yes	No	0	8	7
1140	A:A:G42	A:A:R242	1.5	No	Yes	0	8	9
1141	G:G:K46	G:G:T52	1.5	No	No	0	1	4
1142	B:B:L7	G:G:V16	1.49	No	Yes	0	8	7
1143	B:B:V320	G:G:L50	1.49	Yes	No	0	7	9
1144	A:A:L5	A:A:V13	1.49	Yes	No	0	2	3
1145	A:A:L348	A:A:V354	1.49	Yes	Yes	0	9	8
1146	R:R:N199	R:R:V262	1.48	Yes	No	0	6	5
1147	B:B:L51	B:B:T87	1.47	Yes	No	0	9	5
1148	B:B:D322	B:B:S67	1.47	No	No	0	1	5
1149	A:A:D272	A:A:S326	1.47	No	No	0	9	9
1150	A:A:L346	A:A:T342	1.47	No	No	0	4	7
1151	R:R:I259	R:R:I263	1.47	No	No	0	6	5
1152	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1153	A:A:D200	A:A:V185	1.46	No	No	0	9	5
1154	R:R:N176	R:R:T178	1.46	No	No	0	1	1
1155	A:A:D261	A:A:T260	1.45	No	No	0	4	3
1156	A:A:D261	A:A:T262	1.45	No	Yes	0	4	7
1157	R:R:P64	R:R:R63	1.44	No	No	0	6	6
1158	A:A:Q52	A:A:T187	1.42	No	No	0	9	6
1159	B:B:K15	G:G:L19	1.41	No	No	0	6	9
1160	A:A:K10	A:A:L5	1.41	No	Yes	0	3	2
1161	A:A:L234	A:A:M240	1.41	No	No	0	8	6
1162	A:A:E297	A:A:T295	1.41	No	No	0	4	5
1163	R:R:K196	R:R:L200	1.41	Yes	No	0	3	4
1164	R:R:M62	R:R:N308	1.4	No	No	0	6	6
1165	B:B:A299	B:B:F278	1.39	No	Yes	0	5	7
1166	A:A:P288	A:A:Y287	1.39	No	Yes	0	5	7
1167	A:A:D200	A:A:K46	1.38	No	No	0	9	9
1168	A:A:L353	R:R:L242	1.38	Yes	No	0	7	8
1169	R:R:L242	R:R:L301	1.38	No	Yes	0	8	7
1170	R:R:L290	R:R:L293	1.38	No	No	0	8	5
1171	B:B:E3	G:G:I9	1.37	No	No	0	5	2
1172	B:B:D76	B:B:L55	1.36	Yes	No	0	9	6
1173	A:A:D272	A:A:L273	1.36	No	Yes	0	9	6
1174	B:B:E12	B:B:K15	1.35	No	No	0	4	6
1175	A:A:E239	A:A:M240	1.35	No	No	0	4	6
1176	R:R:D26	R:R:N28	1.35	No	No	0	4	3
1177	G:G:L15	G:G:Q11	1.33	No	No	0	2	3
1178	R:R:E282	R:R:L31	1.33	No	No	0	2	3
1179	R:R:N278	R:R:Q279	1.32	No	No	0	3	3
1180	A:A:E25	A:A:N22	1.31	No	No	0	4	4
1181	A:A:D237	A:A:E238	1.3	No	No	0	8	4
1182	R:R:F48	R:R:T84	1.3	Yes	No	0	6	5
1183	A:A:H244	A:A:N241	1.28	No	No	0	4	9
1184	R:R:E282	R:R:Q279	1.27	No	No	0	2	3
1185	B:B:D267	B:B:H266	1.26	No	Yes	0	3	4
1186	A:A:K317	A:A:R313	1.24	Yes	No	1	7	4
1187	A:A:D20	A:A:R24	1.19	No	No	0	6	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	B:B:T34	4.135	4	8	5
2	B:B:I37	4.9225	4	8	2
3	B:B:R48	4.998	5	3	7
4	B:B:R49	2.835	4	3	7
5	B:B:L51	7.425	4	3	9
6	B:B:H54	7.635	6	3	9
7	B:B:Y59	7.505	6	1	8
8	B:B:M61	3.9525	4	3	6
9	B:B:W63	5.88667	6	3	7
10	B:B:D76	4.82	5	3	9
11	B:B:K78	4.625	4	3	8
12	B:B:L79	3.33	4	6	7
13	B:B:I81	4.2625	4	6	7
14	B:B:W82	9.48833	6	3	9
15	B:B:S84	3.94	4	3	5
16	B:B:Y85	11.2125	4	3	4
17	B:B:N88	5.55	4	0	7
18	B:B:K89	5.61429	7	3	9
19	B:B:H91	5.2725	4	6	5
20	B:B:I93	4.305	4	6	7
21	B:B:L95	4.556	5	6	8
22	B:B:W99	5.51333	9	1	9
23	B:B:Y105	3.64667	6	6	6
24	B:B:N110	6.1925	4	1	4
25	B:B:Y111	5.64	6	1	4
26	B:B:C114	3.42	4	6	8
27	B:B:L117	3.546	5	1	9
28	B:B:N119	4.9975	4	1	9
29	B:B:C121	3.7375	4	1	8
30	B:B:I123	3.17	6	1	6
31	B:B:Y124	4.64714	7	6	6
32	B:B:L126	3.44	4	6	5
33	B:B:T128	3.5075	4	15	3
34	B:B:E130	3.69	4	15	3
35	B:B:V133	4.265	4	6	4
36	B:B:L139	5.326	5	1	9
37	B:B:H142	5.61625	8	1	9
38	B:B:Y145	4.58625	8	1	8
39	B:B:F151	3.7325	8	1	9
40	B:B:L152	4.2575	4	5	3
41	B:B:V158	2.89	4	0	5
42	B:B:T159	5.745	4	1	9
43	B:B:S161	7.4175	4	1	9
44	B:B:G162	3.8	4	1	9
45	B:B:D163	8.835	4	1	9
46	B:B:C166	3.81	4	5	8
47	B:B:L168	3.935	4	5	6
48	B:B:W169	8.795	6	1	8
49	B:B:I171	3.41	4	1	6
50	B:B:Q176	7.5075	4	1	4
51	B:B:T178	4.4475	4	5	4
52	B:B:F180	6.57	6	5	7
53	B:B:H183	7.21167	6	5	9
54	B:B:D186	3.765	6	1	9
55	B:B:V187	4.13	5	5	9
56	B:B:L190	3.2925	4	0	5
57	B:B:L192	3.685	4	5	5
58	B:B:F199	6.29333	6	5	9
59	B:B:V200	3.676	5	4	6
60	B:B:S201	4.915	4	5	9
61	B:B:C204	6.3175	4	1	7
62	B:B:D205	6.6775	4	5	9
63	B:B:S207	4.105	4	5	5
64	B:B:K209	10.655	4	5	6
65	B:B:L210	2.722	5	0	5
66	B:B:W211	9.886	5	5	8
67	B:B:D212	6.26	4	16	9
68	B:B:Q220	6.045	4	4	7
69	B:B:F222	6.494	5	4	8
70	B:B:H225	8.59429	7	4	9
71	B:B:I229	5.055	4	4	7
72	B:B:I232	4.395	4	4	8
73	B:B:F234	3.365	4	0	5
74	B:B:F235	6.435	6	9	6
75	B:B:P236	8.1825	4	9	7
76	B:B:F241	4.97	7	4	6
77	B:B:T243	5.054	5	4	8
78	B:B:D247	7.198	5	4	9
79	B:B:T249	5.745	4	4	6
80	B:B:R251	8.388	5	4	8
81	B:B:F253	6.92	5	4	6
82	B:B:D254	3.79	5	0	9
83	B:B:L255	2.5225	4	4	6
84	B:B:D258	8.518	5	4	7
85	B:B:Q259	2.975	4	0	6
86	B:B:M262	5.408	5	1	4
87	B:B:Y264	5.79667	6	1	5
88	B:B:H266	4.0925	4	0	4
89	B:B:C271	4.22	4	1	5
90	B:B:T274	3.025	4	1	8
91	B:B:F278	4.416	5	9	7
92	B:B:R283	7.378	5	8	9
93	B:B:L284	4.3475	4	0	5
94	B:B:Y289	6.56714	7	1	7
95	B:B:D290	8.5075	4	1	6
96	B:B:N295	9.0225	4	1	6
97	B:B:W297	5.805	4	1	8
98	B:B:L300	5.2275	4	8	6
99	B:B:K301	4.655	4	0	5
100	B:B:R304	6.0575	4	1	5
101	B:B:H311	7.782	5	7	9
102	B:B:R314	11.005	4	1	8
103	B:B:V320	2.8475	4	0	7
104	B:B:T321	5.87	4	3	7
105	B:B:G324	2.295	4	0	9
106	B:B:T329	3.654	5	7	8
107	B:B:G330	2.265	4	0	5
108	B:B:W332	9.99429	7	1	9
109	B:B:D333	7.415	4	7	9
110	B:B:L336	4.455	6	3	7
111	B:B:K337	6.37	4	7	6
112	B:B:W339	7.07	5	7	9
113	A:A:L5	4.0425	4	0	2
114	A:A:I19	2.835	4	3	9
115	A:A:V34	5.4325	4	0	5
116	A:A:L39	3.372	5	1	9
117	A:A:E186	6.235	4	1	9
118	A:A:F191	9.31	4	17	5
119	A:A:K197	7.89	4	1	6
120	A:A:F199	6.744	5	1	5
121	A:A:Q204	3.516	5	1	9
122	A:A:S206	5.0225	4	1	8
123	A:A:R208	3.56	5	1	9
124	A:A:K210	5.04	7	1	9
125	A:A:W211	4.1025	8	1	9
126	A:A:I212	3.262	5	1	8
127	A:A:H213	6.595	4	1	8
128	A:A:C214	5.025	4	1	7
129	A:A:F215	4.2275	8	1	9
130	A:A:I221	4.398	5	1	8
131	A:A:F223	5.29	5	1	9
132	A:A:V225	3.4425	4	0	7
133	A:A:L227	3.895	4	1	7
134	A:A:Y230	8.66167	6	1	8
135	A:A:R242	6.3825	4	0	9
136	A:A:M243	3.7325	4	1	8
137	A:A:L249	3.93	4	1	9
138	A:A:F250	5.14143	7	1	9
139	A:A:I253	3.86	4	1	8
140	A:A:C254	3.992	5	1	5
141	A:A:W258	6.5325	8	1	5
142	A:A:F259	4.656	5	1	9
143	A:A:T262	3.2675	4	1	7
144	A:A:I264	3.9975	4	1	6
145	A:A:L266	4.546	5	1	9
146	A:A:F267	3.19	7	10	9
147	A:A:L268	3.544	5	1	8
148	A:A:L273	2.4575	4	1	6
149	A:A:F274	5.9275	4	1	9
150	A:A:K277	6.486	5	1	9
151	A:A:L283	5.275	6	1	7
152	A:A:Y287	5.47125	8	1	7
153	A:A:Y290	8.8725	4	1	7
154	A:A:Y296	6.554	5	1	4
155	A:A:Y302	9.52	4	1	6
156	A:A:I303	4.296	5	1	7
157	A:A:F307	4.64167	6	1	8
158	A:A:K317	3.77	5	1	7
159	A:A:I319	3.068	5	1	5
160	A:A:Y320	5.25	7	11	7
161	A:A:T321	7.1925	4	1	5
162	A:A:H322	6.9075	4	10	9
163	A:A:F323	3.81	4	1	4
164	A:A:N331	4.04	4	10	8
165	A:A:F334	6.7675	4	0	3
166	A:A:D341	4.4	4	11	8
167	A:A:L348	2.1725	4	2	9
168	A:A:Y351	5.005	6	2	4
169	A:A:L353	3.922	5	2	7
170	A:A:V354	6.0075	4	0	8
171	G:G:V16	3.34	4	0	7
172	G:G:R27	6.6925	4	4	8
173	G:G:Y40	8.5975	4	9	6
174	G:G:D48	6.384	5	0	9
175	G:G:P49	3.0125	4	0	7
176	G:G:L51	4.102	5	8	6
177	G:G:F61	4.23143	7	3	8
178	R:R:K32	4.025	4	2	3
179	R:R:L36	5.0575	4	2	6
180	R:R:F48	5.3575	4	0	6
181	R:R:V54	3.545	4	12	8
182	R:R:T57	3.555	4	12	7
183	R:R:Y58	4.14	5	0	7
184	R:R:M72	4.95	4	2	8
185	R:R:T78	4.9775	4	2	8
186	R:R:F88	6.03	4	2	6
187	R:R:Y92	7.69	4	2	5
188	R:R:Y93	4.756	5	2	5
189	R:R:E97	6.624	5	2	4
190	R:R:W99	6.15429	7	2	9
191	R:R:F101	8.5675	4	2	7
192	R:R:M105	3.21	4	2	6
193	R:R:I109	5.254	5	2	5
194	R:R:R110	4.054	5	2	5
195	R:R:H114	4.98	5	2	6
196	R:R:F115	4.895	6	2	5
197	R:R:N116	4.74	6	2	8
198	R:R:Y118	5.49667	6	2	7
199	R:R:S119	4.395	4	2	7
200	R:R:L122	3.706	5	2	6
201	R:R:F123	7.642	5	2	8
202	R:R:L124	4.8375	4	2	8
203	R:R:T125	3.7675	4	0	7
204	R:R:F127	5.68667	6	2	9
205	R:R:F130	4.83667	6	2	8
206	R:R:R131	6.58667	6	2	9
207	R:R:V134	7.1225	4	2	8
208	R:R:I136	7.515	4	19	8
209	R:R:M139	4.17	4	0	5
210	R:R:W158	6.11	5	2	9
211	R:R:M168	5.9925	4	2	4
212	R:R:T173	4.8575	4	13	4
213	R:R:R180	11.37	4	2	2
214	R:R:C183	5.17	4	2	9
215	R:R:D185	5.164	5	2	5
216	R:R:T187	7.148	5	2	4
217	R:R:E191	5.912	5	13	3
218	R:R:K196	4.5325	4	0	3
219	R:R:Y198	4.6925	4	2	5
220	R:R:N199	4.925	4	0	6
221	R:R:T206	3.956	5	2	5
222	R:R:F207	8.8975	4	0	8
223	R:R:Y218	4.21286	7	2	8
224	R:R:Q230	7.4725	4	0	3
225	R:R:K236	2.8675	4	0	5
226	R:R:L246	4.8675	4	2	8
227	R:R:F254	8.242	5	0	8
228	R:R:F257	4.05714	7	2	7
229	R:R:H258	9.45	4	0	8
230	R:R:R261	5.01833	6	2	5
231	R:R:I272	4.2425	4	0	1
232	R:R:H281	8.195	4	2	4
233	R:R:Y284	6.99	6	2	5
234	R:R:R288	4.79833	6	2	6
235	R:R:F296	4.475	4	0	8
236	R:R:N298	5.066	5	2	9
237	R:R:L301	2.444	5	2	7
238	R:R:Y302	5.16571	7	2	9
239	R:R:F309	6.205	4	12	8
240	W:W:?1	6.305	12	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:C271	B:B:Y289	10.533	4.03	Yes	Yes	1	5	7
2	B:B:C271	B:B:D290	11.5104	4.67	Yes	Yes	1	5	6
3	B:B:D290	B:B:R314	11.6991	21.44	Yes	Yes	1	6	8
4	A:A:K210	B:B:Y145	16.7492	3.58	Yes	Yes	1	9	8
5	A:A:K210	B:B:N230	16.3168	5.6	Yes	No	0	9	9
6	B:B:D246	B:B:N230	16.2383	6.73	No	No	0	9	9
7	B:B:D246	B:B:S227	16.1598	2.94	No	No	0	9	6
8	B:B:D247	B:B:S227	16.0813	2.94	Yes	No	0	9	6
9	B:B:D247	B:B:H225	12.9068	5.04	Yes	Yes	4	9	9
10	A:A:W258	B:B:R314	16.946	3	Yes	Yes	1	5	8
11	A:A:I212	A:A:W258	25.2117	2.35	Yes	Yes	1	8	5
12	A:A:W211	B:B:Y145	18.4559	4.82	Yes	Yes	1	9	8
13	G:G:D48	G:G:L51	11.8739	6.79	Yes	Yes	0	9	6
14	B:B:G324	B:B:T321	13.7261	1.82	Yes	Yes	0	9	7
15	B:B:T321	B:B:W63	14.4435	10.92	Yes	Yes	3	7	7
16	B:B:M61	B:B:W63	17.1268	3.49	Yes	Yes	3	6	7
17	B:B:C317	B:B:M61	23.3962	4.86	No	Yes	0	7	6
18	B:B:C317	B:B:S316	33.1217	3.44	No	No	0	7	9
19	B:B:S316	B:B:W332	33.2541	4.94	No	Yes	0	9	9
20	A:A:L38	A:A:M198	44.1068	4.24	No	No	0	8	7
21	A:A:K46	A:A:L38	100	5.64	No	No	0	9	8
22	A:A:G40	A:A:K46	99.9573	1.74	No	No	0	9	9
23	A:A:G40	A:A:L249	54.3747	1.71	No	Yes	0	9	9
24	A:A:L249	A:A:R208	43.2577	3.64	Yes	Yes	1	9	9
25	A:A:R208	A:A:W211	18.5976	4	Yes	Yes	1	9	9
26	A:A:L36	A:A:M198	43.4289	5.65	No	No	0	7	7
27	A:A:L36	A:A:V34	86.8357	2.98	No	Yes	0	7	5
28	A:A:V339	A:A:V34	86.7905	4.81	No	Yes	0	8	5
29	A:A:I343	A:A:V339	86.7206	3.07	No	No	0	7	8
30	A:A:I343	A:A:N347	86.9611	2.83	No	No	0	7	8
31	A:A:I222	A:A:L38	55.9171	2.85	No	No	0	7	8
32	A:A:I222	A:A:L36	43.4907	2.85	No	No	0	7	7
33	A:A:F259	A:A:I221	24.6264	8.79	Yes	Yes	1	9	8
34	A:A:F223	A:A:L249	20.9821	6.09	Yes	Yes	1	9	9
35	A:A:F223	A:A:V225	14.2495	2.62	Yes	Yes	0	9	7
36	A:A:F267	A:A:I222	12.5484	2.51	Yes	No	0	9	7
37	A:A:F223	A:A:F250	12.3401	12.86	Yes	Yes	1	9	9
38	A:A:F223	A:A:L266	14.099	2.44	Yes	Yes	1	9	9
39	A:A:K270	A:A:S228	10.3173	7.65	No	No	0	9	9
40	A:A:K277	A:A:S228	11.0522	3.06	Yes	No	1	9	9
41	A:A:K277	A:A:Y230	15.4703	8.36	Yes	Yes	1	9	8
42	A:A:L283	A:A:Y230	11.0658	4.69	Yes	Yes	1	7	8
43	A:A:I303	A:A:L283	15.0163	4.28	Yes	Yes	1	7	7
44	A:A:F307	A:A:I303	17.2252	2.51	Yes	Yes	1	8	7
45	A:A:D341	A:A:Y320	10.2807	6.9	Yes	Yes	11	8	7
46	A:A:D341	R:R:K236	10.0458	2.77	Yes	Yes	0	8	5
47	A:A:N347	R:R:V134	86.796	7.39	No	Yes	2	8	8
48	A:A:Y351	R:R:R131	30.1006	2.06	Yes	Yes	2	4	9
49	A:A:Y351	R:R:V134	85.0861	13.88	Yes	Yes	2	4	8
50	A:A:Y351	R:R:S67	28.8131	2.54	Yes	No	0	4	6
51	A:A:Y351	R:R:F127	25.9011	3.09	Yes	Yes	2	4	9
52	R:R:F127	R:R:Y302	23.756	4.13	Yes	Yes	2	9	9
53	R:R:L124	R:R:Y302	23.5178	4.69	Yes	Yes	2	8	9
54	R:R:F250	R:R:L124	21.9645	3.65	No	Yes	0	9	8
55	R:R:F207	R:R:L211	10.1705	6.09	Yes	No	0	8	6
56	R:R:F207	R:R:L255	16.3663	3.65	Yes	No	0	8	5
57	R:R:I259	R:R:L255	14.7306	5.71	No	No	0	6	5
58	R:R:I259	R:R:I263	13.9127	1.47	No	No	0	6	5
59	R:R:I263	R:R:I280	13.0947	2.94	No	No	0	5	5
60	R:R:I280	R:R:S267	12.2767	4.64	No	No	0	5	5
61	R:R:I272	R:R:S267	11.4586	1.55	Yes	No	0	1	5
62	R:R:R131	R:R:Y302	24.1087	6.17	Yes	Yes	2	9	9
63	R:R:F250	R:R:F254	17.1685	9.65	No	Yes	0	9	8
64	R:R:N298	R:R:Y302	24.0371	3.49	Yes	Yes	2	9	9
65	R:R:N294	R:R:N298	17.5644	6.81	No	Yes	0	9	9
66	R:R:F254	R:R:N294	17.1823	10.87	Yes	No	0	8	9
67	R:R:F130	R:R:S67	28.3477	2.64	Yes	No	0	8	6
68	R:R:F130	W:W:?1	27.9504	3.09	Yes	Yes	2	8	0
69	R:R:L122	W:W:?1	14.2099	5.26	Yes	Yes	2	6	0
70	R:R:L122	R:R:T206	12.6001	2.95	Yes	Yes	2	6	5
71	R:R:T206	R:R:Y118	21.9974	7.49	Yes	Yes	2	5	7
72	R:R:R261	R:R:Y118	10.3771	5.14	Yes	Yes	2	5	7
73	R:R:T205	W:W:?1	12.7385	5.6	No	Yes	0	4	0
74	R:R:T205	R:R:T206	12.5487	4.71	No	Yes	0	4	5
75	R:R:H114	R:R:Y118	11.1825	3.27	Yes	Yes	2	6	7
76	R:R:H114	R:R:R288	10.0316	2.26	Yes	Yes	2	6	6
77	R:R:R110	R:R:R288	20.8457	3.2	Yes	Yes	2	5	6
78	R:R:F254	R:R:L117	24.7771	3.65	Yes	No	0	8	8
79	R:R:F257	R:R:L117	24.2547	2.44	Yes	No	0	7	8
80	R:R:F257	R:R:R288	20.0448	2.14	Yes	Yes	2	7	6
81	R:R:C183	R:R:R110	12.7341	4.18	Yes	Yes	2	9	5
82	A:A:G40	A:A:L39	45.5719	1.71	No	Yes	0	9	9
83	A:A:I221	A:A:L39	24.9109	2.85	Yes	Yes	1	8	9
84	A:A:F259	A:A:W258	24.5396	2	Yes	Yes	1	9	5
85	A:A:I212	A:A:R208	24.6174	5.01	Yes	Yes	1	8	9
86	A:A:F223	A:A:L39	19.8385	2.44	Yes	Yes	1	9	9
87	A:A:W258	B:B:W332	32.1634	3.75	Yes	Yes	1	5	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F130	R:R:S67	2.64	2	Yes	No	8	6	1	2
R:R:C126	R:R:I71	3.27	2	No	No	7	7	2	2
R:R:F130	R:R:I71	6.28	2	Yes	No	8	7	1	2
R:R:L122	R:R:V157	4.47	2	Yes	No	6	7	1	2
R:R:I160	R:R:L122	2.85	2	No	Yes	4	6	1	1
R:R:L122	R:R:S161	3	2	Yes	No	6	8	1	2
R:R:L122	R:R:T206	2.95	2	Yes	Yes	6	5	1	2
R:R:L122	W:W:?1	5.26	2	Yes	Yes	6	0	1	0
R:R:P210	R:R:T125	6.99	0	No	Yes	8	7	2	1
R:R:I213	R:R:T125	3.04	0	No	Yes	7	7	2	1
R:R:T125	R:R:V214	3.17	0	Yes	No	7	8	1	2
R:R:T125	W:W:?1	1.87	0	Yes	Yes	7	0	1	0
R:R:C126	R:R:F130	4.19	2	No	Yes	7	8	2	1
R:R:F130	R:R:I144	10.05	2	Yes	No	8	4	1	1
R:R:A153	R:R:F130	2.77	0	No	Yes	6	8	2	1
R:R:F130	W:W:?1	3.09	2	Yes	Yes	8	0	1	0
R:R:C133	R:R:I144	4.91	2	No	No	5	4	1	1
R:R:C133	W:W:?1	2.01	2	No	Yes	5	0	1	0
R:R:C141	W:W:?1	6.03	0	No	Yes	6	0	1	0
R:R:I144	W:W:?1	5.43	2	No	Yes	4	0	1	0
R:R:R148	W:W:?1	6.16	0	No	Yes	4	0	1	0
R:R:C149	W:W:?1	16.09	0	No	Yes	3	0	1	0
R:R:V152	W:W:?1	16.99	0	No	Yes	2	0	1	0
R:R:I160	R:R:V156	3.07	2	No	No	4	4	1	2
R:R:I160	W:W:?1	3.62	2	No	Yes	4	0	1	0
R:R:T205	R:R:T206	4.71	0	No	Yes	4	5	1	2
R:R:T205	W:W:?1	5.6	0	No	Yes	4	0	1	0
R:R:L209	W:W:?1	3.51	0	No	Yes	5	0	1	0
R:R:I201	R:R:T205	1.52	0	No	No	4	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
38.46	Single	9NS9	Compound 187	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
36.36	Single	5KW2	PubChem 133053953	5KW2-FFA1-PubChem 133053953
35.71	Single	8XXU	A1D5Q	8XXU-DP₂-A1D5Q-Gi1/β1/γ2
33.33	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
33.33	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
33.33	Single	8K9L	BMS-986122	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
33.33	Single	9CM3	Compound 187	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
33.33	Single	9CM7	AZ-1729	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
31.58	Single	8XXV	A1D5Q	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
31.25	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
31.25	Single	8Y72	BMS-986122	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
29.41	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
27.27	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
26.67	Single	6OBA	GTPL11074	6OBA-β₂-S-Alprenolol-GTPL11074
26.32	Single	9IYB	A1D5Q	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
23.53	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
22.22	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
21.05	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
17.65	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
17.65	Single	9K1C	DHA	9K1C-FFA1-DHA-Gi1/β1/γ2
16.67	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
13.33	Single	5XSZ	Glyceryl-mono-oleate	5XSZ-LPA₆-Glyceryl-mono-oleate
11.11	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
11.11	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/β1/γ2
10.53	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
10.53	Single	9JCQ	LPC	9JCQ-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
10.00	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
10.00	Single	8IYX	YL-365	8IYX-GPR34-YL-365
10.00	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
9.38	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
9.09	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
9.09	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
8.70	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/β1/γ2
8.70	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
8.70	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
8.33	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
8.33	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
8.00	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
8.00	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
7.69	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
7.41	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
5.56	Single	8J6Q	Compound 9n	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
5.56	Single	8WG8	Peptide	8WG8-Glucagon-Peptide-chim(NtGi1-Gs)/β1/γ2
5.26	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
5.26	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.26	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/β1/γ2
5.26	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.26	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.00	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
5.00	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
5.00	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
5.00	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
4.76	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
4.55	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
4.17	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
4.17	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
4.17	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
4.17	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
4.17	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
4.17	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
4.17	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
4.17	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
4.00	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
4.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
4.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
4.00	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
4.00	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.00	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
3.85	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
3.85	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
3.85	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
3.85	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
3.85	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
3.70	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
3.57	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
3.57	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
3.45	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
3.23	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
3.12	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
3.03	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
3.03	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.03	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.03	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
2.94	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
2.86	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
2.63	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
2.63	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
2.38	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2

PDB Summary
PDB	8YYX
Class	A
SubFamily	Alicarboxylic acid
Type	Oxoglutarate
SubType	Oxoglutarate
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	Leukotriene e4
Protein Partners	chim(Gi1-CtGq)/Beta1/Gamma2
PDB Resolution	2.84
Date	2025-04-09
D.O.I.	To be published

Net Summary
I_min	1.82
Number of Linked Nodes	870
Number of Links	1187
Number of Hubs	240
Number of Links mediated by Hubs	830
Number of Communities	19
Number of Nodes involved in Communities	326
Number of Links involved in Communities	541

Path Summary
Number Of Nodes in MetaPath	88
Number Of Links MetaPath	87
Number of Shortest Paths	4601063
Length Of Smallest Path	3
Average Path Length	29.3123
Length of Longest Path	54
Minimum Path Strength	1.295
Average Path Strength	4.70082
Maximum Path Strength	21.32
Minimum Path Correlation	0.7
Average Path Correlation	0.991703
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.125
Average % Of Corr. Nodes	38.7084
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	55.3428
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_W_
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	_W_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8YYX_Chain_B S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8YYX_Chain_A G C T L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K S T I V K Q M T G I V E T H F T F K D L H F K M F D V G Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E D E E M N R M H E S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C T D T N F V F A V D I N L K L A S E I R A K T L Q L E Y N V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8YYX_Chain_G S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q96P68
Sequence	>8YYX_Chain_R N C T D E N I P L K M H Y L P V I Y G I I F L V G F P G N A V V I S T Y I F K M R P W K S S T I I M L N L A C T D L L Y L T S L P F L I H Y Y A S G E N W I F G D F M C K F I R F S F H F N L Y S S I L F L T C F S I F R Y C V I I H P M S C F S I H K T R C A V V A C A V V W I I S L V A V I P M T F L I T S T N R T N R S A C L D L T S S D E L N T I K W Y N L I L T A T T F C L P L V I V T L C Y T T I I H T L T H G L Q T D S C L K Q K A R R L T I L L L L A F Y V C F L P F H I L R V I R I E S R L L S I S C S I E N Q I H E A Y I V S R P L A A L N T F G N L L L Y V V V S D N F Q Q A V C S T V R C K V S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8YYX	A	Alicarboxylic acid	Oxoglutarate	Oxoglutarate	Homo sapiens	-	Leukotriene e4	chim(Gi1-CtGq)/β1/γ2	2.84	2025-04-09	To be published
	8YYX (No Gprot)	A	Alicarboxylic acid	Oxoglutarate	Oxoglutarate	Homo sapiens	-	Leukotriene e4		2.84	2025-04-09	To be published
	8YYW	A	Alicarboxylic acid	Oxoglutarate	Oxoglutarate	Homo sapiens	α-ketoglutarate	α-ketoglutarate	chim(Gi1-CtGq)/β1/γ2	3.19	2025-04-09	To be published
	8YYW (No Gprot)	A	Alicarboxylic acid	Oxoglutarate	Oxoglutarate	Homo sapiens	α-ketoglutarate	α-ketoglutarate		3.19	2025-04-09	To be published

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