psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:E15	A:A:L12	5.3	No	No	12	5	2
2	A:A:D16	A:A:L12	5.43	No	No	12	4	2
3	A:A:D16	A:A:E15	6.5	No	No	12	4	5
4	A:A:R22	B:B:H91	3.39	No	Yes	0	5	5
5	A:A:S23	B:B:N88	8.94	No	Yes	0	7	7
6	A:A:I26	B:B:K89	5.82	No	Yes	0	9	9
7	A:A:E27	A:A:Q31	3.82	No	No	0	6	4
8	A:A:E27	B:B:K89	10.8	No	Yes	0	6	9
9	A:A:D33	A:A:Q29	3.92	No	No	0	5	4
10	A:A:D33	A:A:L30	4.07	No	No	8	5	5
11	A:A:L30	B:B:K78	4.23	No	Yes	8	5	8
12	A:A:D33	B:B:K78	8.3	No	Yes	8	5	8
13	A:A:K34	A:A:R38	6.19	No	No	0	4	4
14	A:A:K34	B:B:L55	8.46	No	No	0	4	6
15	A:A:Q35	R:R:E260	5.1	No	No	0	3	6
16	A:A:Q35	R:R:R261	4.67	No	No	0	3	5
17	A:A:R42	A:A:Y37	14.4	No	Yes	0	9	4
18	A:A:Y37	B:B:L55	7.03	Yes	No	8	4	6
19	A:A:Y37	B:B:D76	3.45	Yes	Yes	8	4	9
20	A:A:N218	A:A:T40	5.85	No	No	0	4	7
21	A:A:H220	A:A:T40	6.85	Yes	No	0	7	7
22	A:A:F219	A:A:H41	9.05	Yes	Yes	0	8	6
23	A:A:H41	A:A:T242	13.69	Yes	No	0	6	8
24	A:A:H41	A:A:I383	6.63	Yes	No	0	6	8
25	A:A:H41	R:R:T257	8.21	Yes	No	0	6	7
26	A:A:F219	A:A:L43	4.87	Yes	No	0	8	7
27	A:A:F238	A:A:L44	19.49	No	No	0	9	9
28	A:A:I244	A:A:L44	7.14	No	No	0	8	9
29	A:A:K53	A:A:L45	4.23	Yes	No	0	9	8
30	A:A:L45	A:A:M221	8.48	No	Yes	0	8	8
31	A:A:G47	A:A:L46	3.42	No	No	0	9	8
32	A:A:F246	A:A:L46	3.65	Yes	No	0	9	8
33	A:A:G47	A:A:S51	3.71	No	Yes	13	9	9
34	A:A:G47	A:A:K53	5.23	No	Yes	13	9	9
35	A:A:A48	A:A:S51	3.42	No	Yes	0	8	9
36	A:A:D49	A:A:N50	5.39	No	Yes	14	8	9
37	A:A:D49	A:A:R265	10.72	No	No	14	8	9
38	A:A:N50	A:A:S252	4.47	Yes	No	0	9	8
39	A:A:N50	A:A:R265	10.85	Yes	No	14	9	9
40	A:A:G52	A:A:S51	3.71	No	Yes	0	9	9
41	A:A:K53	A:A:S51	4.59	Yes	Yes	13	9	9
42	A:A:S51	A:A:V247	4.85	Yes	No	0	9	7
43	A:A:D223	A:A:K53	9.68	No	Yes	0	9	9
44	A:A:I56	A:A:N292	5.66	No	No	0	7	9
45	A:A:K58	A:A:V57	4.55	No	No	0	9	7
46	A:A:T210	A:A:V57	4.76	No	No	0	7	7
47	A:A:F212	A:A:Q59	9.37	Yes	No	5	9	9
48	A:A:M221	A:A:Q59	5.44	Yes	No	5	8	9
49	A:A:F212	A:A:R61	6.41	Yes	No	0	9	8
50	A:A:A372	A:A:R61	5.53	No	No	0	8	8
51	A:A:I62	A:A:Q213	4.12	No	No	0	9	3
52	A:A:K203	A:A:S205	9.18	Yes	No	0	7	7
53	A:A:K203	B:B:I120	4.36	Yes	No	0	7	6
54	A:A:K203	B:B:A140	6.42	Yes	No	0	7	5
55	A:A:G206	B:B:N119	3.39	No	No	0	8	9
56	A:A:F208	A:A:F222	6.43	Yes	Yes	1	5	7
57	A:A:F208	A:A:V224	3.93	Yes	No	1	5	9
58	A:A:F208	B:B:W99	7.02	Yes	Yes	1	5	9
59	A:A:F208	B:B:L117	4.87	Yes	No	1	5	9
60	A:A:E209	A:A:K211	5.4	Yes	No	1	9	4
61	A:A:E209	A:A:H220	6.15	Yes	Yes	1	9	7
62	A:A:E209	A:A:F222	7	Yes	Yes	1	9	7
63	A:A:H220	A:A:K211	9.17	Yes	No	1	7	4
64	A:A:F212	A:A:F219	12.86	Yes	Yes	5	9	8
65	A:A:F212	A:A:M221	3.73	Yes	Yes	5	9	8
66	A:A:N218	A:A:Q213	9.24	No	No	0	4	3
67	A:A:D215	A:A:V214	5.84	No	Yes	5	5	6
68	A:A:F219	A:A:V214	3.93	Yes	Yes	5	8	6
69	A:A:R373	A:A:V214	3.92	No	Yes	5	5	6
70	A:A:F376	A:A:V214	3.93	Yes	Yes	5	8	6
71	A:A:D215	A:A:R373	11.91	No	No	5	5	5
72	A:A:D215	A:A:F376	10.75	No	Yes	5	5	8
73	A:A:F219	A:A:V217	3.93	Yes	No	0	8	5
74	A:A:F219	A:A:F376	4.29	Yes	Yes	5	8	8
75	A:A:C379	A:A:F219	6.98	No	Yes	0	8	8
76	A:A:F222	A:A:H220	3.39	Yes	Yes	1	7	7
77	A:A:F222	B:B:W99	19.04	Yes	Yes	1	7	9
78	A:A:Q227	A:A:V224	5.73	Yes	No	1	9	9
79	A:A:V224	A:A:W234	11.03	No	Yes	1	9	9
80	A:A:Q227	A:A:W234	5.48	Yes	Yes	1	9	9
81	A:A:Q227	B:B:N119	5.28	Yes	No	0	9	9
82	A:A:Q227	B:B:Y145	10.15	Yes	Yes	1	9	8
83	A:A:E230	A:A:R228	9.3	No	No	0	9	9
84	A:A:R228	B:B:T164	5.17	No	No	0	9	6
85	A:A:R228	B:B:D186	7.15	No	No	0	9	9
86	A:A:D229	A:A:E230	6.5	No	No	0	8	9
87	A:A:E230	A:A:R232	6.98	No	No	0	9	8
88	A:A:R231	A:A:W234	8	No	Yes	0	9	9
89	A:A:D272	A:A:R231	10.72	Yes	No	0	8	9
90	A:A:I276	A:A:R231	3.76	No	No	0	8	9
91	A:A:R232	B:B:D228	7.15	No	Yes	0	8	9
92	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
93	A:A:K233	B:B:M188	11.52	Yes	No	0	9	8
94	A:A:K233	B:B:C204	4.85	Yes	No	1	9	7
95	A:A:K233	B:B:D228	8.3	Yes	Yes	1	9	9
96	A:A:K233	B:B:N230	8.39	Yes	No	0	9	9
97	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
98	A:A:F238	A:A:W234	4.01	No	Yes	0	9	9
99	A:A:W234	B:B:Y145	5.79	Yes	Yes	1	9	8
100	A:A:Q236	A:A:W281	20.81	No	Yes	1	8	5
101	A:A:Q236	B:B:R314	3.5	No	Yes	1	8	8
102	A:A:C237	B:B:Y59	6.72	No	Yes	1	8	8
103	A:A:C237	B:B:M101	4.86	No	No	1	8	9
104	A:A:F238	B:B:W99	13.03	No	Yes	0	9	9
105	A:A:D240	A:A:N239	4.04	No	Yes	1	6	8
106	A:A:N239	A:A:W281	4.52	Yes	Yes	1	8	5
107	A:A:N239	B:B:K57	5.6	Yes	Yes	1	8	9
108	A:A:N239	B:B:W332	5.65	Yes	Yes	1	8	9
109	A:A:D240	B:B:K57	9.68	No	Yes	1	6	9
110	A:A:I244	A:A:L282	5.71	No	No	0	8	9
111	A:A:I244	A:A:I285	5.89	No	No	0	8	7
112	A:A:D272	A:A:F246	4.78	Yes	Yes	0	8	9
113	A:A:F246	A:A:F273	5.36	Yes	Yes	0	9	9
114	A:A:F246	A:A:L289	3.65	Yes	No	0	9	9
115	A:A:N292	A:A:V247	4.43	No	No	0	9	7
116	A:A:F345	A:A:V248	6.55	Yes	No	0	8	7
117	A:A:Q294	A:A:S250	5.78	Yes	No	4	6	6
118	A:A:L297	A:A:S250	4.5	Yes	No	4	8	6
119	A:A:L297	A:A:Y253	3.52	Yes	No	0	8	8
120	A:A:K300	A:A:Y253	27.47	No	No	0	9	8
121	A:A:Y253	A:A:Y311	6.95	No	Yes	0	8	6
122	A:A:N264	A:A:Y311	9.3	No	Yes	0	9	6
123	A:A:F312	A:A:L266	8.53	Yes	No	0	8	8
124	A:A:I341	A:A:L266	4.28	No	No	0	8	8
125	A:A:L270	A:A:Q267	5.32	No	No	0	6	4
126	A:A:N271	A:A:Q267	7.92	No	No	0	5	4
127	A:A:F312	A:A:Q267	7.03	Yes	No	0	8	4
128	A:A:E344	A:A:L270	3.98	Yes	No	0	5	6
129	A:A:F345	A:A:L270	8.53	Yes	No	0	8	6
130	A:A:F273	A:A:W277	5.01	Yes	Yes	15	9	6
131	A:A:F273	A:A:V287	5.24	Yes	No	15	9	6
132	A:A:F273	A:A:F345	6.43	Yes	Yes	0	9	8
133	A:A:F273	A:A:I348	5.02	Yes	No	0	9	4
134	A:A:C359	A:A:F273	4.19	No	Yes	0	5	9
135	A:A:K274	A:A:N278	5.6	No	No	0	5	8
136	A:A:I348	A:A:K274	4.36	No	No	0	4	5
137	A:A:N278	A:A:W277	6.78	No	Yes	0	8	6
138	A:A:V287	A:A:W277	4.9	No	Yes	15	6	6
139	A:A:S349	A:A:W277	8.65	No	Yes	0	7	6
140	A:A:H357	A:A:W277	22.22	No	Yes	0	7	6
141	A:A:N279	A:A:W281	6.78	No	Yes	0	8	5
142	A:A:L282	A:A:N279	9.61	No	No	0	9	8
143	A:A:R280	A:A:W281	13.99	No	Yes	0	5	5
144	A:A:R280	B:B:D246	4.76	No	Yes	0	5	9
145	A:A:W281	B:B:R314	9	Yes	Yes	1	5	8
146	A:A:R283	A:A:R356	6.4	No	No	0	3	2
147	A:A:I382	A:A:S286	7.74	No	No	0	6	8
148	A:A:F290	A:A:I288	3.77	Yes	No	0	9	9
149	A:A:D378	A:A:I288	12.59	No	No	0	7	9
150	A:A:L289	A:A:L291	5.54	No	No	0	9	8
151	A:A:F345	A:A:L289	8.53	Yes	No	0	8	9
152	A:A:F290	A:A:H362	4.53	Yes	No	0	9	9
153	A:A:F290	A:A:T364	9.08	Yes	Yes	9	9	9
154	A:A:F290	A:A:N371	4.83	Yes	Yes	9	9	9
155	A:A:L291	A:A:Q294	5.32	No	Yes	4	8	6
156	A:A:F363	A:A:L291	4.87	Yes	No	4	5	8
157	A:A:N292	A:A:T364	7.31	No	Yes	0	9	9
158	A:A:K293	A:A:L296	8.46	No	No	0	9	6
159	A:A:L297	A:A:Q294	5.32	Yes	Yes	4	8	6
160	A:A:F363	A:A:Q294	8.2	Yes	Yes	4	5	6
161	A:A:D295	A:A:L296	5.43	No	No	0	9	6
162	A:A:C365	A:A:D295	7.78	No	No	0	8	9
163	A:A:K300	A:A:K305	17.24	No	No	0	9	3
164	A:A:A337	A:A:V301	3.39	No	No	0	8	7
165	A:A:S306	A:A:Y311	3.82	No	Yes	0	7	6
166	A:A:E309	A:A:K307	21.6	No	No	0	4	6
167	A:A:F315	A:A:K307	8.69	Yes	No	0	6	6
168	A:A:F312	A:A:I308	3.77	Yes	No	0	8	7
169	A:A:F315	A:A:I308	13.82	Yes	No	0	6	7
170	A:A:D310	A:A:Y311	4.6	No	Yes	0	3	6
171	A:A:E344	A:A:F312	8.16	Yes	Yes	0	5	8
172	A:A:E314	A:A:R347	3.49	No	No	0	6	4
173	A:A:F315	A:A:R336	14.97	Yes	No	0	6	5
174	A:A:F315	A:A:F340	13.93	Yes	No	0	6	7
175	A:A:P321	A:A:Y318	4.17	Yes	Yes	0	5	6
176	A:A:R336	A:A:Y318	4.12	No	Yes	0	5	6
177	A:A:F340	A:A:Y318	15.47	No	Yes	0	7	6
178	A:A:D343	A:A:Y318	4.6	No	Yes	0	3	6
179	A:A:P321	A:A:T320	3.5	Yes	No	0	5	1
180	A:A:A324	A:A:P321	5.61	No	Yes	4	3	5
181	A:A:P321	A:A:Y339	6.95	Yes	Yes	4	5	3
182	A:A:A324	A:A:Y339	9.34	No	Yes	4	3	3
183	A:A:P326	A:A:T325	3.5	No	No	0	1	2
184	A:A:E327	A:A:K338	4.05	No	No	0	4	5
185	A:A:E330	A:A:V334	7.13	No	No	0	3	4
186	A:A:D331	A:A:P332	6.44	No	No	0	4	1
187	A:A:D331	A:A:R333	19.06	No	No	0	4	5
188	A:A:K338	A:A:Y339	5.97	No	Yes	4	5	3
189	A:A:F363	A:A:K338	13.65	Yes	No	4	5	5
190	A:A:R342	A:A:Y339	9.26	Yes	Yes	4	4	3
191	A:A:F363	A:A:Y339	6.19	Yes	Yes	4	5	3
192	A:A:E344	A:A:F340	18.66	Yes	No	0	5	7
193	A:A:D343	A:A:R342	8.34	No	Yes	0	3	4
194	A:A:L346	A:A:R342	8.5	No	Yes	4	4	4
195	A:A:P361	A:A:R342	5.76	No	Yes	4	5	4
196	A:A:F363	A:A:R342	5.34	Yes	Yes	4	5	4
197	A:A:E344	A:A:R347	4.65	Yes	No	0	5	4
198	A:A:L346	A:A:P361	4.93	No	No	4	4	5
199	A:A:S349	A:A:T350	4.8	No	No	0	7	4
200	A:A:C359	A:A:S349	3.44	No	No	0	5	7
201	A:A:G353	A:A:S352	3.71	No	No	0	4	5
202	A:A:G353	A:A:R356	4.5	No	No	0	4	2
203	A:A:G355	A:A:Y358	4.35	No	Yes	0	2	4
204	A:A:H357	A:A:R356	5.64	No	No	0	7	2
205	A:A:R385	A:A:Y358	6.17	No	Yes	0	5	4
206	A:A:Y358	R:R:R336	7.2	Yes	No	0	4	5
207	A:A:Y358	R:R:Q337	7.89	Yes	No	0	4	7
208	A:A:D378	A:A:Y360	13.79	No	Yes	0	7	8
209	A:A:D381	A:A:Y360	10.34	No	Yes	0	8	8
210	A:A:I382	A:A:Y360	4.84	No	Yes	0	6	8
211	A:A:Y360	R:R:R336	11.32	Yes	No	0	8	5
212	A:A:H362	A:A:R374	16.93	No	Yes	0	9	4
213	A:A:D378	A:A:H362	10.08	No	No	0	7	9
214	A:A:D368	A:A:T364	5.78	Yes	Yes	9	9	9
215	A:A:N371	A:A:T364	7.31	Yes	Yes	9	9	9
216	A:A:D368	A:A:E370	14.29	Yes	No	9	9	4
217	A:A:D368	A:A:N371	4.04	Yes	Yes	9	9	9
218	A:A:D368	A:A:R374	5.96	Yes	Yes	9	9	4
219	A:A:E370	A:A:R374	12.79	No	Yes	9	4	4
220	A:A:N371	A:A:R374	4.82	Yes	Yes	9	9	4
221	A:A:N377	A:A:R373	7.23	No	No	5	4	5
222	A:A:F376	A:A:N377	3.62	Yes	No	5	8	4
223	A:A:F376	A:A:R380	18.17	Yes	No	5	8	7
224	A:A:N377	A:A:R380	12.05	No	No	5	4	7
225	A:A:D381	A:A:R385	8.34	No	No	0	8	5
226	A:A:D381	R:R:K332	5.53	No	No	0	8	9
227	A:A:H387	A:A:I383	3.98	No	No	0	8	8
228	A:A:Q384	R:R:K332	9.49	No	No	0	6	9
229	A:A:H387	A:A:M386	5.25	No	No	0	8	3
230	A:A:M386	A:A:Q390	8.16	No	No	0	3	4
231	A:A:H387	R:R:L252	19.28	No	No	0	8	8
232	A:A:L388	A:A:L394	5.54	No	Yes	0	8	8
233	A:A:L388	R:R:L253	4.15	No	No	0	8	8
234	A:A:L394	A:A:R389	3.64	Yes	No	0	8	4
235	A:A:Y391	R:R:R173	13.38	No	Yes	0	4	9
236	A:A:Y391	R:R:E245	6.73	No	Yes	0	4	9
237	A:A:Y391	R:R:L249	11.72	No	No	0	4	9
238	A:A:E392	R:R:N404	15.77	No	No	0	6	9
239	A:A:E392	R:R:K405	6.75	No	No	0	6	6
240	A:A:L393	R:R:L329	6.92	Yes	No	18	8	9
241	A:A:L393	R:R:T351	4.42	Yes	No	18	8	9
242	A:A:L394	R:R:L333	5.54	Yes	No	16	8	7
243	B:B:L4	B:B:L7	5.54	Yes	Yes	19	4	8
244	B:B:L4	B:B:R8	3.64	Yes	No	0	4	3
245	B:B:L4	G:G:S8	4.5	Yes	No	0	4	4
246	B:B:L4	G:G:I9	9.99	Yes	No	19	4	2
247	B:B:D5	B:B:R8	4.76	No	No	0	1	3
248	B:B:L7	B:B:Q6	6.65	Yes	No	0	8	1
249	B:B:Q6	B:B:Q9	5.12	No	No	0	1	3
250	B:B:L7	G:G:I9	4.28	Yes	No	19	8	2
251	B:B:E10	B:B:Q9	3.82	No	No	0	8	3
252	B:B:Q13	B:B:Q9	8.96	No	No	0	1	3
253	B:B:E10	G:G:V16	8.56	No	No	0	8	7
254	B:B:E12	B:B:Q13	11.47	No	No	0	4	1
255	B:B:N16	B:B:R19	6.03	No	No	0	1	4
256	B:B:I18	B:B:R22	6.26	Yes	No	0	7	6
257	B:B:I18	G:G:E22	4.1	Yes	Yes	0	7	9
258	B:B:K23	B:B:R19	4.95	No	No	0	2	4
259	B:B:D258	B:B:R22	11.91	Yes	No	0	7	6
260	B:B:Q259	B:B:R22	4.67	No	No	0	6	6
261	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
262	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
263	B:B:A26	G:G:V30	3.39	No	No	0	3	8
264	B:B:D27	G:G:K29	11.06	Yes	No	0	8	4
265	B:B:D27	G:G:S31	7.36	Yes	No	0	8	9
266	B:B:S31	B:B:T29	4.8	No	No	0	1	3
267	B:B:Q32	B:B:T29	5.67	No	No	0	1	3
268	B:B:L30	B:B:T34	5.9	No	No	0	5	5
269	B:B:L30	G:G:A34	4.73	No	No	0	5	6
270	B:B:N35	B:B:Q32	5.28	No	No	0	1	1
271	B:B:I37	B:B:T34	7.6	Yes	No	0	2	5
272	B:B:I37	B:B:L300	4.28	Yes	No	0	2	6
273	B:B:I37	B:B:K301	8.72	Yes	Yes	0	2	5
274	B:B:D38	B:B:P39	6.44	No	No	0	1	1
275	B:B:I43	B:B:V40	6.14	No	Yes	0	3	3
276	B:B:D298	B:B:V40	8.76	Yes	Yes	0	9	3
277	B:B:Q44	B:B:R42	17.52	No	No	0	4	2
278	B:B:I43	B:B:M45	4.37	No	No	0	3	4
279	B:B:I43	B:B:L284	5.71	No	No	0	3	5
280	B:B:R46	B:B:R48	23.46	No	No	0	5	7
281	B:B:T47	B:B:W339	9.7	No	Yes	0	3	9
282	B:B:N340	B:B:R48	4.82	No	No	0	9	7
283	B:B:R49	B:B:T87	5.17	No	No	0	7	5
284	B:B:R49	G:G:F61	5.34	No	Yes	0	7	8
285	B:B:R52	B:B:T50	12.94	No	No	0	7	3
286	B:B:K337	B:B:T50	9.01	No	No	0	6	3
287	B:B:L51	B:B:W82	17.08	No	Yes	0	9	9
288	B:B:I338	B:B:L51	4.28	No	No	0	5	9
289	B:B:F335	B:B:R52	9.62	No	No	0	4	7
290	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
291	B:B:H54	B:B:S72	11.16	Yes	No	0	9	9
292	B:B:H54	B:B:S74	13.95	Yes	No	8	9	9
293	B:B:D76	B:B:H54	5.04	Yes	Yes	8	9	9
294	B:B:H54	B:B:I80	13.26	Yes	No	0	9	8
295	B:B:D76	B:B:L55	10.86	Yes	No	8	9	6
296	B:B:K57	B:B:Y59	16.72	Yes	Yes	1	9	8
297	B:B:K57	B:B:Q75	10.85	Yes	No	1	9	9
298	B:B:K57	B:B:W332	15.08	Yes	Yes	1	9	9
299	B:B:Q75	B:B:Y59	21.42	No	Yes	1	9	8
300	B:B:M101	B:B:Y59	3.59	No	Yes	1	9	8
301	B:B:W332	B:B:Y59	10.61	Yes	Yes	1	9	8
302	B:B:M61	B:B:W63	8.14	No	Yes	10	6	7
303	B:B:L70	B:B:M61	4.24	Yes	No	10	5	6
304	B:B:C317	B:B:M61	4.86	No	No	0	7	6
305	B:B:H62	B:B:R150	11.28	No	No	0	6	6
306	B:B:L70	B:B:W63	10.25	Yes	Yes	10	5	7
307	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
308	B:B:T321	B:B:W63	10.92	No	Yes	10	7	7
309	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
310	B:B:I338	B:B:W63	4.7	No	Yes	0	5	7
311	B:B:G64	B:B:Y105	4.35	No	No	0	5	6
312	B:B:D66	B:B:L69	4.07	No	No	0	8	5
313	B:B:S67	B:B:T321	4.8	No	No	10	5	7
314	B:B:D323	B:B:S67	10.31	No	No	10	7	5
315	B:B:D83	B:B:R68	15.48	No	No	0	8	5
316	B:B:R68	B:B:Y85	22.64	No	No	0	5	4
317	B:B:L70	B:B:W82	4.56	Yes	Yes	0	5	9
318	B:B:L336	B:B:L70	4.15	No	Yes	0	7	5
319	B:B:L79	B:B:V71	4.47	No	No	0	7	8
320	B:B:S72	B:B:W82	6.18	No	Yes	0	9	9
321	B:B:A73	B:B:C103	3.61	No	No	0	9	8
322	B:B:D76	B:B:S74	10.31	Yes	No	8	9	9
323	B:B:Q75	B:B:W99	6.57	No	Yes	1	9	9
324	B:B:D76	B:B:K78	6.91	Yes	Yes	8	9	8
325	B:B:K78	B:B:P94	6.69	Yes	No	0	8	5
326	B:B:L79	B:B:L95	5.54	No	No	0	7	8
327	B:B:I80	B:B:W82	14.09	No	Yes	0	8	9
328	B:B:H91	B:B:I81	7.95	Yes	No	0	5	7
329	B:B:I81	B:B:L126	4.28	No	No	0	7	5
330	B:B:K89	B:B:W82	11.6	Yes	Yes	0	9	9
331	B:B:D83	B:B:T86	8.67	No	No	0	8	6
332	B:B:S84	G:G:F61	5.28	No	Yes	0	5	8
333	B:B:Y85	G:G:P60	11.13	No	No	0	4	9
334	B:B:Y85	G:G:F61	7.22	No	Yes	0	4	8
335	B:B:N88	B:B:T86	8.77	Yes	No	0	7	6
336	B:B:H91	B:B:V90	5.54	Yes	No	0	5	5
337	B:B:H91	B:B:V133	5.54	Yes	No	0	5	4
338	B:B:I93	B:B:P94	3.39	No	No	0	7	5
339	B:B:I93	B:B:Y124	8.46	No	Yes	0	7	6
340	B:B:I93	B:B:V133	7.68	No	No	0	7	4
341	B:B:L95	B:B:Y124	5.86	No	Yes	0	8	6
342	B:B:R96	B:B:V135	3.92	No	No	0	6	4
343	B:B:E138	B:B:R96	5.82	No	No	0	6	6
344	B:B:D118	B:B:S97	8.83	No	No	0	9	8
345	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
346	B:B:L117	B:B:W99	3.42	No	Yes	1	9	9
347	B:B:M101	B:B:Y145	7.18	No	Yes	1	9	8
348	B:B:C149	B:B:T102	5.07	No	No	0	8	8
349	B:B:G109	B:B:Y105	5.79	No	No	0	5	6
350	B:B:V112	B:B:Y105	3.79	No	No	0	8	6
351	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
352	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
353	B:B:N110	B:B:S108	8.94	No	No	0	4	6
354	B:B:D154	B:B:S108	8.83	No	No	0	6	6
355	B:B:N110	B:B:Y111	3.49	No	Yes	0	4	4
356	B:B:K127	B:B:N110	8.39	No	No	0	4	4
357	B:B:N125	B:B:Y111	11.63	No	Yes	0	4	4
358	B:B:D154	B:B:Y111	8.05	No	Yes	0	6	4
359	B:B:V112	B:B:Y124	3.79	No	Yes	0	8	6
360	B:B:L126	B:B:V112	5.96	No	No	0	5	8
361	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
362	B:B:C114	B:B:S122	3.44	No	No	21	8	8
363	B:B:C114	B:B:Y124	4.03	No	Yes	21	8	6
364	B:B:D118	B:B:I120	7	No	No	0	9	6
365	B:B:G144	B:B:N119	3.39	No	No	0	8	9
366	B:B:E138	B:B:I120	5.47	No	No	0	6	6
367	B:B:C121	B:B:L139	4.76	No	No	0	8	9
368	B:B:S122	B:B:Y124	3.82	No	Yes	21	8	6
369	B:B:E138	B:B:S122	4.31	No	No	0	6	8
370	B:B:F151	B:B:I123	3.77	Yes	No	0	9	6
371	B:B:I123	B:B:I171	7.36	No	No	0	6	6
372	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
373	B:B:E130	B:B:N132	6.57	No	No	0	3	3
374	B:B:I171	B:B:R137	3.76	No	No	0	6	5
375	B:B:L139	B:B:W169	14.81	No	Yes	0	9	8
376	B:B:H142	B:B:L146	5.14	Yes	No	6	9	7
377	B:B:H142	B:B:T159	6.85	Yes	Yes	6	9	9
378	B:B:H142	B:B:S161	16.74	Yes	No	6	9	9
379	B:B:D163	B:B:H142	3.78	Yes	Yes	6	9	9
380	B:B:H142	B:B:T165	4.11	Yes	No	6	9	7
381	B:B:A167	B:B:H142	4.39	No	Yes	6	4	9
382	B:B:H142	B:B:W169	7.41	Yes	Yes	6	9	8
383	B:B:H142	B:B:Q176	4.95	Yes	Yes	6	9	4
384	B:B:D163	B:B:T143	11.56	Yes	No	0	9	5
385	B:B:D163	B:B:G144	5.03	Yes	No	0	9	8
386	B:B:G162	B:B:Y145	7.24	No	Yes	1	9	8
387	B:B:D186	B:B:Y145	10.34	No	Yes	1	9	8
388	B:B:L146	B:B:T159	5.9	No	Yes	6	7	9
389	B:B:S147	B:B:S160	4.89	No	No	0	9	6
390	B:B:C148	B:B:R150	5.57	No	No	0	6	6
391	B:B:C148	B:B:L190	6.35	No	No	0	6	5
392	B:B:L192	B:B:R150	4.86	Yes	No	0	5	6
393	B:B:F151	B:B:I157	13.82	Yes	No	0	9	7
394	B:B:L152	B:B:Q156	7.99	No	No	0	3	5
395	B:B:L152	B:B:L192	4.15	No	Yes	0	3	5
396	B:B:L152	B:B:T196	4.42	No	No	0	3	1
397	B:B:D153	B:B:Q156	13.05	No	No	0	5	5
398	B:B:D170	B:B:N155	6.73	No	No	0	9	3
399	B:B:E172	B:B:N155	11.83	No	No	0	6	3
400	B:B:L168	B:B:Q156	6.65	No	No	0	6	5
401	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
402	B:B:L192	B:B:V158	4.47	Yes	No	3	5	5
403	B:B:F199	B:B:V158	3.93	Yes	No	3	9	5
404	B:B:T159	B:B:W169	8.49	Yes	Yes	6	9	8
405	B:B:S160	B:B:V187	6.46	No	No	0	6	9
406	B:B:D163	B:B:S161	10.31	Yes	No	6	9	9
407	B:B:S161	B:B:T165	4.8	No	No	6	9	7
408	B:B:D186	B:B:G162	5.03	No	No	1	9	9
409	B:B:D163	B:B:T165	11.56	Yes	No	6	9	7
410	B:B:C166	B:B:F180	4.19	No	Yes	3	8	7
411	B:B:C166	B:B:F199	5.59	No	Yes	3	8	9
412	B:B:C166	B:B:S201	3.44	No	No	0	8	9
413	B:B:A167	B:B:W169	5.19	No	Yes	6	4	8
414	B:B:A167	B:B:Q176	6.06	No	Yes	6	4	4
415	B:B:L168	B:B:T178	5.9	No	No	0	6	4
416	B:B:Q176	B:B:W169	15.33	Yes	Yes	6	4	8
417	B:B:D170	B:B:T173	10.12	No	No	0	9	5
418	B:B:G174	B:B:T173	3.64	No	No	0	4	5
419	B:B:Q175	B:B:T173	4.25	No	No	0	4	5
420	B:B:T177	B:B:T178	4.71	No	No	0	4	4
421	B:B:F180	B:B:T178	5.19	Yes	No	0	7	4
422	B:B:F180	B:B:F199	9.65	Yes	Yes	3	7	9
423	B:B:F180	B:B:W211	11.02	Yes	Yes	3	7	8
424	B:B:H183	B:B:V187	4.15	Yes	No	3	9	9
425	B:B:H183	B:B:S201	5.58	Yes	No	0	9	9
426	B:B:A203	B:B:H183	8.78	No	Yes	3	8	9
427	B:B:D205	B:B:H183	5.04	No	Yes	3	9	9
428	B:B:H183	B:B:S207	8.37	Yes	No	3	9	5
429	B:B:H183	B:B:K209	18.34	Yes	Yes	3	9	6
430	B:B:D205	B:B:T184	5.78	No	No	0	9	3
431	B:B:A203	B:B:V187	3.39	No	No	3	8	9
432	B:B:I232	B:B:S189	7.74	No	No	0	8	7
433	B:B:F234	B:B:S191	7.93	No	No	0	5	8
434	B:B:F199	B:B:L192	3.65	Yes	Yes	3	9	5
435	B:B:A193	B:B:D195	4.63	No	No	0	4	5
436	B:B:A193	B:B:F234	5.55	No	No	0	4	5
437	B:B:G238	B:B:P194	4.06	No	No	0	7	4
438	B:B:D195	B:B:R197	5.96	No	No	0	5	5
439	B:B:D195	B:B:L198	4.07	No	No	0	5	3
440	B:B:R197	B:B:R214	13.86	No	No	0	5	9
441	B:B:L198	B:B:L210	6.92	No	Yes	0	3	5
442	B:B:F199	B:B:W211	10.02	Yes	Yes	3	9	8
443	B:B:L210	B:B:V200	4.47	Yes	Yes	0	5	6
444	B:B:I232	B:B:V200	4.61	No	Yes	0	8	6
445	B:B:F234	B:B:V200	10.49	No	Yes	0	5	6
446	B:B:F241	B:B:V200	6.55	Yes	Yes	0	6	6
447	B:B:S201	B:B:W211	7.41	No	Yes	0	9	8
448	B:B:G202	B:B:I232	3.53	No	No	0	6	8
449	B:B:C204	B:B:D228	4.67	No	Yes	1	7	9
450	B:B:D205	B:B:S207	10.31	No	No	3	9	5
451	B:B:K209	B:B:W211	9.28	Yes	Yes	3	6	8
452	B:B:C218	B:B:K209	6.47	No	Yes	3	5	6
453	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
454	B:B:L210	B:B:Q220	6.65	Yes	Yes	0	5	7
455	B:B:L210	B:B:L255	6.92	Yes	No	0	5	6
456	B:B:C218	B:B:W211	5.22	No	Yes	3	5	8
457	B:B:D212	B:B:E215	14.29	No	No	22	9	3
458	B:B:D212	B:B:R219	15.48	No	No	22	9	5
459	B:B:E215	B:B:R214	3.49	No	No	0	3	9
460	B:B:E215	B:B:R219	5.82	No	No	22	3	5
461	B:B:M217	B:B:R219	4.96	No	No	0	3	5
462	B:B:M217	G:G:M21	4.33	No	No	0	3	1
463	B:B:C218	G:G:Q18	6.1	No	No	0	5	9
464	B:B:F222	B:B:Q220	8.2	Yes	Yes	2	8	7
465	B:B:D258	B:B:Q220	6.53	Yes	Yes	2	7	7
466	B:B:Q220	G:G:E22	7.65	Yes	Yes	2	7	9
467	B:B:F222	B:B:F241	6.43	Yes	Yes	2	8	6
468	B:B:F222	B:B:F253	6.43	Yes	Yes	2	8	6
469	B:B:D258	B:B:F222	4.78	Yes	Yes	2	7	8
470	B:B:H225	B:B:I229	10.61	Yes	No	2	9	7
471	B:B:H225	B:B:T243	10.95	Yes	No	2	9	8
472	B:B:H225	B:B:S245	12.55	Yes	No	2	9	9
473	B:B:D247	B:B:H225	6.3	Yes	Yes	2	9	9
474	B:B:H225	B:B:R251	18.05	Yes	Yes	2	9	8
475	B:B:F253	B:B:H225	4.53	Yes	Yes	2	6	9
476	B:B:D247	B:B:E226	9.09	Yes	No	0	9	3
477	B:B:D228	B:B:S227	5.89	Yes	No	0	9	6
478	B:B:D228	B:B:D246	3.99	Yes	Yes	0	9	9
479	B:B:I229	B:B:T243	9.12	No	No	2	7	8
480	B:B:D246	B:B:N230	6.73	Yes	No	0	9	9
481	B:B:C233	B:B:V276	3.42	No	No	0	3	6
482	B:B:F235	B:B:P236	10.11	Yes	Yes	7	6	7
483	B:B:F235	B:B:N237	9.67	Yes	Yes	7	6	5
484	B:B:F235	B:B:F278	9.65	Yes	Yes	7	6	7
485	B:B:F235	B:B:G282	4.52	Yes	No	7	6	9
486	B:B:F235	G:G:L37	10.96	Yes	No	0	6	7
487	B:B:F235	G:G:Y40	6.19	Yes	Yes	7	6	6
488	B:B:F278	B:B:P236	5.78	Yes	Yes	7	7	7
489	B:B:G282	B:B:P236	4.06	No	Yes	7	9	7
490	B:B:P236	G:G:Y40	6.95	Yes	Yes	7	7	6
491	B:B:G238	B:B:N237	3.39	No	Yes	0	7	5
492	B:B:N237	B:B:N239	12.26	Yes	No	0	5	2
493	B:B:N237	G:G:Y40	6.98	Yes	Yes	7	5	6
494	B:B:N239	B:B:R256	9.64	No	No	0	2	9
495	B:B:F241	B:B:F253	11.79	Yes	Yes	2	6	6
496	B:B:A242	B:B:F278	4.16	No	Yes	0	4	7
497	B:B:F253	B:B:T243	7.78	Yes	No	2	6	8
498	B:B:G244	B:B:I273	3.53	No	No	0	5	6
499	B:B:D247	B:B:S245	5.89	Yes	No	2	9	9
500	B:B:D246	B:B:G272	5.03	Yes	No	0	9	4
501	B:B:D247	B:B:T249	7.23	Yes	No	0	9	6
502	B:B:S265	B:B:T249	4.8	No	No	0	2	6
503	B:B:C250	B:B:Y264	5.38	No	Yes	0	8	5
504	B:B:C250	B:B:I273	6.55	No	No	0	8	6
505	B:B:F253	B:B:R251	4.28	Yes	Yes	2	6	8
506	B:B:E260	B:B:R251	3.49	No	Yes	2	6	8
507	B:B:R251	B:B:T263	7.76	Yes	No	0	8	1
508	B:B:L252	B:B:L261	4.15	No	No	0	7	5
509	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
510	B:B:E260	B:B:F253	11.66	No	Yes	2	6	6
511	B:B:D254	B:B:L261	6.79	No	No	0	9	5
512	B:B:R256	G:G:I28	5.01	No	No	0	9	4
513	B:B:R256	G:G:D36	7.15	No	No	0	9	5
514	B:B:D258	G:G:E22	6.5	Yes	Yes	2	7	9
515	B:B:D258	G:G:R27	11.91	Yes	Yes	2	7	8
516	B:B:M262	B:B:Y264	8.38	No	Yes	0	4	5
517	B:B:A302	B:B:M262	4.83	No	No	0	2	4
518	B:B:L285	B:B:Y264	4.69	Yes	Yes	7	6	5
519	B:B:W297	B:B:Y264	9.65	No	Yes	0	8	5
520	B:B:A299	B:B:Y264	4	No	Yes	7	5	5
521	B:B:H266	B:B:N268	10.2	No	No	0	4	4
522	B:B:H266	B:B:R304	5.64	No	No	0	4	5
523	B:B:I269	B:B:Y289	3.63	No	Yes	0	4	7
524	B:B:C271	B:B:Y289	4.03	No	Yes	23	5	7
525	B:B:C271	B:B:D290	6.22	No	No	0	5	6
526	B:B:C271	B:B:D291	6.22	No	No	23	5	8
527	B:B:I273	B:B:Y289	7.25	No	Yes	0	6	7
528	B:B:R314	B:B:T274	5.17	Yes	No	0	8	8
529	B:B:L318	B:B:S275	6.01	Yes	No	0	6	8
530	B:B:L285	B:B:V276	4.47	Yes	No	0	6	6
531	B:B:A287	B:B:V276	3.39	No	No	0	6	6
532	B:B:L318	B:B:S277	4.5	Yes	No	0	6	5
533	B:B:S277	B:B:V320	4.85	No	No	0	5	7
534	B:B:F278	B:B:L285	7.31	Yes	Yes	7	7	6
535	B:B:S279	G:G:D48	8.83	No	Yes	24	9	9
536	B:B:S279	G:G:L50	6.01	No	No	24	9	9
537	B:B:G324	B:B:K280	3.49	No	No	0	9	1
538	B:B:K280	G:G:D48	5.53	No	Yes	0	1	9
539	B:B:S281	G:G:D48	8.83	No	Yes	0	9	9
540	B:B:D298	B:B:R283	13.1	Yes	No	0	9	9
541	B:B:L300	B:B:R283	10.93	No	No	0	6	9
542	B:B:L284	B:B:V296	4.47	No	No	0	5	5
543	B:B:A299	B:B:L285	4.73	No	Yes	7	5	6
544	B:B:L286	B:B:V296	4.47	No	No	0	7	5
545	B:B:L286	B:B:L318	4.15	No	Yes	0	7	6
546	B:B:L286	B:B:V327	4.47	No	No	0	7	6
547	B:B:A287	B:B:Y289	4	No	Yes	0	6	7
548	B:B:D291	B:B:Y289	4.6	No	Yes	23	8	7
549	B:B:N295	B:B:Y289	11.63	No	Yes	0	6	7
550	B:B:W297	B:B:Y289	9.65	No	Yes	0	8	7
551	B:B:D290	B:B:R314	14.29	No	Yes	0	6	8
552	B:B:D291	B:B:N293	8.08	No	No	0	8	5
553	B:B:F292	B:B:N313	4.83	No	No	0	4	7
554	B:B:F292	R:R:R413	6.41	No	No	0	4	7
555	B:B:N293	B:B:V307	4.43	No	No	0	5	3
556	B:B:C294	B:B:L308	6.35	No	No	0	5	7
557	B:B:N295	B:B:R304	8.44	No	No	0	6	5
558	B:B:N295	B:B:V307	7.39	No	No	0	6	3
559	B:B:R304	B:B:W297	7	No	No	0	5	8
560	B:B:D298	B:B:K301	4.15	Yes	Yes	20	9	5
561	B:B:D298	B:B:D303	3.99	Yes	No	20	9	2
562	B:B:D303	B:B:K301	4.15	No	Yes	20	2	5
563	B:B:G306	R:R:K422	3.49	No	No	0	4	5
564	B:B:L308	B:B:W339	14.81	No	Yes	0	7	9
565	B:B:A309	R:R:R417	6.91	No	No	0	3	7
566	B:B:H311	B:B:V315	5.54	Yes	No	0	9	7
567	B:B:H311	B:B:T329	6.85	Yes	No	0	9	8
568	B:B:H311	B:B:S331	16.74	Yes	No	25	9	9
569	B:B:D333	B:B:H311	7.56	Yes	Yes	25	9	9
570	B:B:H311	B:B:K337	7.86	Yes	No	0	9	6
571	B:B:D312	B:B:D333	5.32	No	Yes	0	5	9
572	B:B:D312	R:R:S167	7.36	No	No	0	5	8
573	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
574	B:B:R314	B:B:W332	23.99	Yes	Yes	1	8	9
575	B:B:C317	B:B:S316	3.44	No	No	0	7	9
576	B:B:S316	B:B:W332	6.18	No	Yes	0	9	9
577	B:B:L318	B:B:T329	4.42	Yes	No	0	6	8
578	B:B:V320	B:B:V327	4.81	No	No	0	7	6
579	B:B:D323	B:B:T321	7.23	No	No	10	7	7
580	B:B:D323	B:B:M325	6.93	No	No	0	7	5
581	B:B:G324	G:G:P49	4.06	No	No	0	9	7
582	B:B:M325	G:G:P60	8.39	No	No	0	5	9
583	B:B:A326	G:G:F61	5.55	No	Yes	0	7	8
584	B:B:V327	G:G:L50	4.47	No	No	0	6	9
585	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
586	B:B:G330	B:B:L336	3.42	No	No	0	5	7
587	B:B:D333	B:B:S331	8.83	Yes	No	25	9	9
588	B:B:D333	B:B:F335	11.94	Yes	No	0	9	4
589	B:B:K337	B:B:W339	6.96	No	Yes	0	6	9
590	B:B:I338	G:G:F61	3.77	No	Yes	0	5	8
591	B:B:N340	G:G:N59	10.9	No	Yes	0	9	9
592	B:B:N340	G:G:F61	3.62	No	Yes	0	9	8
593	G:G:I9	G:G:R13	20.04	No	No	0	2	6
594	G:G:K14	G:G:R13	3.71	No	No	0	4	6
595	G:G:E17	G:G:K20	6.75	No	No	0	6	6
596	G:G:E17	G:G:M21	9.47	No	No	0	6	1
597	G:G:E22	G:G:R27	3.49	Yes	Yes	2	9	8
598	G:G:I25	G:G:R27	5.01	No	Yes	0	2	8
599	G:G:H44	G:G:Y40	13.07	No	Yes	0	6	6
600	G:G:E47	G:G:K46	4.05	No	No	0	3	1
601	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
602	G:G:D48	G:G:L50	4.07	Yes	No	24	9	9
603	G:G:D48	G:G:L51	5.43	Yes	No	0	9	6
604	G:G:P49	G:G:V54	3.53	No	Yes	0	7	6
605	G:G:P53	G:G:T52	3.5	No	No	0	8	4
606	G:G:P55	G:G:V54	5.3	No	Yes	11	5	6
607	G:G:E58	G:G:V54	4.28	No	Yes	11	5	6
608	G:G:N59	G:G:V54	5.91	Yes	Yes	0	9	6
609	G:G:P55	G:G:S57	3.56	No	No	11	5	6
610	G:G:E58	G:G:P55	11	No	No	11	5	5
611	G:G:A56	G:G:R62	4.15	No	No	0	4	7
612	G:G:E58	G:G:S57	7.19	No	No	11	5	6
613	G:G:N59	G:G:P60	6.52	Yes	No	0	9	9
614	G:G:N59	G:G:R62	4.82	Yes	No	0	9	7
615	R:R:A135	R:R:Y138	4	No	No	0	3	5
616	R:R:M137	R:R:Y138	3.59	No	No	0	4	5
617	R:R:F141	R:R:M137	3.73	Yes	No	0	6	4
618	R:R:F141	R:R:S140	3.96	Yes	No	0	6	4
619	R:R:F141	R:R:F383	11.79	Yes	Yes	0	6	5
620	R:R:F141	R:R:L386	6.09	Yes	No	0	6	7
621	R:R:Q142	R:R:Y145	13.53	No	Yes	0	5	7
622	R:R:F383	R:R:M144	4.98	Yes	No	26	5	6
623	R:R:F387	R:R:M144	3.73	Yes	No	26	5	6
624	R:R:T146	R:R:Y145	6.24	No	Yes	0	7	7
625	R:R:D195	R:R:Y145	10.34	No	Yes	0	7	7
626	R:R:L386	R:R:Y145	5.86	No	Yes	0	7	7
627	R:R:F391	R:R:G148	9.03	Yes	No	0	7	7
628	R:R:K187	R:R:Y149	5.97	No	Yes	0	8	8
629	R:R:V191	R:R:Y149	20.19	No	Yes	0	7	8
630	R:R:S390	R:R:Y149	8.9	No	Yes	0	9	8
631	R:R:A188	R:R:L153	4.73	No	Yes	0	8	6
632	R:R:F181	R:R:L156	4.87	No	Yes	0	8	8
633	R:R:F184	R:R:L156	6.09	Yes	Yes	27	8	8
634	R:R:L156	R:R:V185	4.47	Yes	No	0	8	8
635	R:R:G393	R:R:L156	3.42	No	Yes	27	9	8
636	R:R:F402	R:R:L158	6.09	No	No	0	9	5
637	R:R:A159	R:R:C401	3.61	No	Yes	0	9	9
638	R:R:F181	R:R:L160	6.09	No	No	0	8	6
639	R:R:L163	R:R:N174	4.12	Yes	No	0	8	9
640	R:R:E410	R:R:L166	6.63	No	No	0	8	7
641	R:R:L166	R:R:R414	7.29	No	No	0	7	5
642	R:R:E410	R:R:S167	4.31	No	No	0	8	8
643	R:R:H170	R:R:L169	9	No	No	0	7	9
644	R:R:C171	R:R:R173	5.57	No	Yes	0	7	9
645	R:R:T172	R:R:Y248	11.24	No	Yes	0	7	8
646	R:R:S262	R:R:T172	6.4	No	No	0	5	7
647	R:R:N174	R:R:R173	6.03	No	Yes	0	9	9
648	R:R:H177	R:R:R173	6.77	No	Yes	0	9	9
649	R:R:A175	R:R:F264	4.16	No	No	0	6	6
650	R:R:I176	R:R:W241	4.7	No	Yes	0	9	9
651	R:R:E245	R:R:I176	5.47	Yes	No	0	9	9
652	R:R:I176	R:R:Y248	6.04	No	Yes	0	9	8
653	R:R:E245	R:R:H177	13.54	Yes	No	0	9	9
654	R:R:H177	R:R:Y400	13.07	No	No	0	9	8
655	R:R:N179	R:R:W241	15.82	No	Yes	28	8	9
656	R:R:F264	R:R:N179	4.83	No	No	0	6	8
657	R:R:N179	R:R:W272	3.39	No	Yes	28	8	9
658	R:R:F184	R:R:L180	6.09	Yes	No	0	8	9
659	R:R:L180	R:R:L242	5.54	No	No	0	9	9
660	R:R:N238	R:R:S183	5.96	No	No	0	9	9
661	R:R:F184	R:R:N238	21.75	Yes	No	0	8	9
662	R:R:F184	R:R:Q392	10.54	Yes	No	0	8	9
663	R:R:F184	R:R:G393	4.52	Yes	No	27	8	9
664	R:R:F184	R:R:V396	5.24	Yes	No	0	8	9
665	R:R:F230	R:R:L186	10.96	No	No	0	4	7
666	R:R:I235	R:R:K187	5.82	No	No	0	5	8
667	R:R:M231	R:R:S190	7.67	Yes	No	0	6	5
668	R:R:L198	R:R:Y202	3.52	No	No	0	6	1
669	R:R:C224	R:R:C294	5.46	No	No	0	9	9
670	R:R:C287	R:R:R225	8.36	No	No	0	3	8
671	R:R:Q293	R:R:R225	19.86	No	No	0	4	8
672	R:R:M231	R:R:T296	4.52	Yes	No	0	6	5
673	R:R:K286	R:R:Q232	5.42	No	No	0	8	7
674	R:R:Q232	R:R:W304	4.38	No	Yes	0	7	6
675	R:R:W272	R:R:Y233	6.75	Yes	Yes	0	9	9
676	R:R:P275	R:R:Y233	9.74	Yes	Yes	0	9	9
677	R:R:V279	R:R:Y233	3.79	No	Yes	0	6	9
678	R:R:P275	R:R:V236	3.53	Yes	No	0	9	6
679	R:R:L307	R:R:V236	4.47	No	No	0	7	6
680	R:R:A237	R:R:P275	3.74	No	Yes	0	7	9
681	R:R:V311	R:R:Y239	5.05	No	No	0	8	8
682	R:R:C240	R:R:P275	3.77	No	Yes	0	6	9
683	R:R:V244	R:R:W241	7.36	No	Yes	0	8	9
684	R:R:G271	R:R:W241	8.44	No	Yes	0	9	9
685	R:R:W241	R:R:W272	17.81	Yes	Yes	28	9	9
686	R:R:L243	R:R:L247	5.54	No	No	0	8	7
687	R:R:L243	R:R:N318	5.49	No	Yes	0	8	9
688	R:R:V244	R:R:Y267	3.79	No	No	0	8	7
689	R:R:E245	R:R:L358	3.98	Yes	Yes	0	9	9
690	R:R:G246	R:R:L358	3.42	No	Yes	0	9	9
691	R:R:L252	R:R:Y248	5.86	No	Yes	0	8	8
692	R:R:Y248	R:R:Y267	11.91	Yes	No	0	8	7
693	R:R:L249	R:R:L253	4.15	No	No	0	9	8
694	R:R:I325	R:R:L249	4.28	No	No	0	9	9
695	R:R:H250	R:R:I321	9.28	No	No	0	7	8
696	R:R:H250	R:R:R324	3.39	No	No	0	7	8
697	R:R:L253	R:R:L328	4.15	No	No	0	8	8
698	R:R:L255	R:R:P259	4.93	No	No	0	5	6
699	R:R:E260	R:R:F263	3.5	No	No	0	6	5
700	R:R:F263	R:R:R261	9.62	No	No	0	5	5
701	R:R:F264	R:R:L268	7.31	No	No	0	6	5
702	R:R:A274	R:R:F278	4.16	No	Yes	0	4	5
703	R:R:M276	R:R:V280	10.65	No	Yes	0	3	2
704	R:R:L277	W:W:D11	5.43	No	No	0	4	0
705	R:R:F278	R:R:P310	14.45	Yes	No	0	5	9
706	R:R:F278	W:W:M10	4.98	Yes	No	0	5	0
707	R:R:L307	R:R:V279	4.47	No	No	0	7	6
708	R:R:P281	R:R:V280	3.53	No	Yes	0	4	2
709	R:R:V285	R:R:W282	3.68	No	Yes	0	5	9
710	R:R:I306	R:R:W282	8.22	No	Yes	29	8	9
711	R:R:W282	W:W:F5	8.02	Yes	No	29	9	0
712	R:R:W282	W:W:M10	4.65	Yes	No	0	9	0
713	R:R:K286	R:R:Q293	4.07	No	No	0	8	4
714	R:R:W295	R:R:W304	4.69	No	Yes	0	9	6
715	R:R:F303	R:R:W305	9.02	No	No	0	4	7
716	R:R:L307	R:R:W304	7.97	No	Yes	0	7	6
717	R:R:I306	W:W:F5	6.28	No	No	29	8	0
718	R:R:R308	R:R:V311	14.38	No	No	0	6	8
719	R:R:F312	R:R:R308	13.9	No	No	0	5	6
720	R:R:F309	W:W:V9	3.93	No	No	0	4	0
721	R:R:F312	R:R:V363	7.87	No	No	0	5	6
722	R:R:I321	R:R:N318	4.25	No	Yes	0	8	9
723	R:R:F319	R:R:V323	5.24	No	No	0	7	5
724	R:R:F319	R:R:H361	9.05	No	No	0	7	8
725	R:R:F322	R:R:V326	5.24	No	No	0	9	7
726	R:R:F322	R:R:I355	5.02	No	No	0	9	8
727	R:R:Q327	R:R:R324	4.67	No	No	0	8	8
728	R:R:L329	R:R:T351	4.42	No	No	18	9	9
729	R:R:R334	R:R:V330	5.23	No	No	0	7	6
730	R:R:K344	R:R:L333	5.64	No	No	0	6	7
731	R:R:K344	R:R:R334	3.71	No	No	0	6	7
732	R:R:R346	R:R:Y343	4.12	No	No	0	8	7
733	R:R:F345	R:R:K344	3.72	No	No	0	7	6
734	R:R:K349	R:R:L352	4.23	No	No	0	9	8
735	R:R:L357	R:R:L358	5.54	No	Yes	0	9	9
736	R:R:L357	R:R:V396	7.45	No	No	0	9	9
737	R:R:L357	R:R:Y400	10.55	No	No	0	9	8
738	R:R:F365	R:R:V364	3.93	No	No	0	7	6
739	R:R:D385	R:R:F365	5.97	No	No	0	7	7
740	R:R:R378	R:R:V368	7.85	No	No	0	4	5
741	R:R:Q374	R:R:R378	3.5	No	No	0	4	4
742	R:R:L382	R:R:R378	15.79	No	No	0	5	4
743	R:R:D385	R:R:L382	5.43	No	No	0	7	5
744	R:R:F383	R:R:F384	8.57	Yes	No	0	5	4
745	R:R:F383	R:R:F387	5.36	Yes	Yes	26	5	5
746	R:R:F387	R:R:L388	3.65	Yes	No	0	5	6
747	R:R:F387	R:R:F391	7.5	Yes	Yes	0	5	7
748	R:R:F391	R:R:S390	3.96	Yes	No	0	7	9
749	R:R:L395	R:R:L399	6.92	No	No	0	6	8
750	R:R:F402	R:R:V398	3.93	No	No	0	9	6
751	R:R:E406	R:R:N404	14.46	Yes	No	17	9	9
752	R:R:N404	R:R:V407	10.35	No	No	17	9	9
753	R:R:K405	R:R:Q408	5.42	No	No	0	6	7
754	R:R:E406	R:R:V407	5.7	Yes	No	17	9	9
755	R:R:E410	R:R:R413	4.65	No	No	0	8	7
756	R:R:H416	R:R:R412	3.39	No	No	0	3	5
757	R:R:R414	R:R:R417	13.86	No	No	0	5	7
758	R:R:H416	R:R:W415	6.35	No	No	0	3	5
759	R:R:R419	R:R:W415	6	No	No	0	5	5
760	R:R:R419	R:R:W418	13	No	No	0	5	3
761	R:R:G421	R:R:L420	3.42	No	No	0	4	4
762	R:R:K422	R:R:L420	4.23	No	No	0	5	4
763	W:W:P3	W:W:S6	5.34	No	No	0	0	0
764	W:W:N7	W:W:P3	14.66	No	No	0	0	0
765	W:W:F5	W:W:P4	5.78	No	No	0	0	0
766	B:B:C148	B:B:T102	3.38	No	No	0	6	8
767	B:B:C149	B:B:T159	3.38	No	Yes	0	8	9
768	B:B:K301	B:B:P39	3.35	Yes	No	0	5	1
769	R:R:L252	R:R:P259	3.28	No	No	0	8	6
770	R:R:C401	R:R:I162	3.27	Yes	No	0	9	8
771	A:A:I26	B:B:A92	3.25	No	No	0	9	6
772	A:A:A243	A:A:I288	3.25	No	No	0	8	9
773	A:A:D323	A:A:P321	3.22	No	Yes	0	4	5
774	A:A:V301	A:A:V334	3.21	No	No	0	7	4
775	A:A:S366	A:A:T55	3.2	No	No	0	9	9
776	R:R:S379	R:R:T376	3.2	No	No	0	3	2
777	B:B:L300	G:G:C41	3.17	No	No	0	6	7
778	R:R:C401	R:R:L163	3.17	Yes	Yes	0	9	8
779	B:B:L7	G:G:A12	3.15	Yes	No	0	8	5
780	R:R:A314	R:R:L243	3.15	No	No	0	8	8
781	A:A:E327	A:A:P328	3.14	No	No	0	4	1
782	A:A:A249	A:A:N50	3.13	No	Yes	0	8	9
783	A:A:C365	A:A:D368	3.11	No	Yes	0	8	9
784	B:B:I33	G:G:S31	3.1	No	No	0	3	9
785	R:R:I306	W:W:S6	3.1	No	No	0	8	0
786	B:B:A28	B:B:D27	3.09	No	Yes	0	4	8
787	B:B:A257	B:B:D254	3.09	No	No	0	7	9
788	B:B:D254	G:G:A33	3.09	No	No	0	9	7
789	A:A:I285	A:A:V241	3.07	No	No	0	7	9
790	A:A:I245	A:A:V375	3.07	No	No	0	7	9
791	A:A:K17	A:A:S13	3.06	No	No	0	3	7
792	A:A:K24	A:A:V20	3.04	No	No	0	4	3
793	A:A:I285	A:A:T284	3.04	No	No	0	7	4
794	R:R:M231	R:R:V191	3.04	Yes	No	0	6	7
795	B:B:Q17	G:G:A23	3.03	No	No	0	4	8
796	A:A:A298	A:A:E299	3.02	No	No	0	4	6
797	G:G:A43	G:G:E42	3.02	No	No	0	4	1
798	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
799	A:A:K203	A:A:T204	3	Yes	No	0	7	9
800	A:A:L296	A:A:S251	3	No	No	0	6	9
801	A:A:L297	A:A:S251	3	Yes	No	0	8	9
802	R:R:R308	R:R:W304	3	No	Yes	0	6	6
803	A:A:L43	A:A:V375	2.98	No	No	0	7	9
804	A:A:L297	A:A:V301	2.98	Yes	No	0	8	7
805	B:B:L69	B:B:V90	2.98	No	No	0	5	5
806	B:B:L95	B:B:V100	2.98	No	No	0	8	9
807	B:B:L261	G:G:V30	2.98	No	No	0	5	8
808	R:R:L157	R:R:V185	2.98	No	No	0	3	8
809	R:R:L394	R:R:V398	2.98	No	No	0	5	6
810	R:R:L403	R:R:V398	2.98	No	No	0	5	6
811	R:R:N298	R:R:V191	2.96	No	No	0	6	7
812	R:R:I317	R:R:I321	2.94	No	No	0	6	8
813	G:G:A43	G:G:H44	2.93	No	No	0	4	6
814	B:B:D27	G:G:V30	2.92	Yes	No	0	8	8
815	B:B:I37	G:G:M38	2.92	Yes	No	0	2	4
816	R:R:I194	R:R:M231	2.92	No	Yes	0	6	6
817	G:G:I28	G:G:K32	2.91	No	No	0	4	5
818	R:R:G234	R:R:Y233	2.9	No	Yes	0	5	9
819	B:B:D322	B:B:T65	2.89	No	No	0	1	1
820	G:G:Q11	G:G:S8	2.89	No	No	0	3	4
821	R:R:F309	R:R:P310	2.89	No	No	0	4	9
822	A:A:K28	A:A:M25	2.88	No	No	0	4	4
823	A:A:L393	R:R:I355	2.85	Yes	No	0	8	8
824	B:B:I18	G:G:L19	2.85	Yes	Yes	0	7	9
825	R:R:I162	R:R:L411	2.85	No	No	0	8	5
826	R:R:E290	R:R:V292	2.85	No	No	0	6	4
827	R:R:I355	R:R:L358	2.85	No	Yes	0	8	9
828	B:B:Q176	B:B:T179	2.83	Yes	No	0	4	4
829	B:B:K15	G:G:L19	2.82	No	Yes	0	6	9
830	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
831	R:R:C401	R:R:F402	2.79	Yes	No	0	9	9
832	A:A:F376	R:R:A256	2.77	Yes	No	5	8	7
833	A:A:R380	R:R:A256	2.77	No	No	5	7	7
834	A:A:L393	R:R:L354	2.77	Yes	No	0	8	9
835	B:B:L14	G:G:L19	2.77	No	Yes	0	8	9
836	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
837	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
838	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
839	R:R:L153	R:R:L157	2.77	Yes	No	0	6	3
840	R:R:L354	R:R:L399	2.77	No	No	0	9	8
841	R:R:L255	R:R:N251	2.75	No	No	0	5	7
842	R:R:L266	W:W:N15	2.75	No	No	0	3	0
843	R:R:L358	R:R:N318	2.75	Yes	Yes	0	9	9
844	B:B:I18	B:B:Q17	2.74	Yes	No	0	7	4
845	B:B:E172	B:B:I171	2.73	No	No	0	6	6
846	B:B:N35	B:B:N36	2.72	No	No	0	1	1
847	A:A:E21	A:A:M25	2.71	No	No	0	3	4
848	A:A:K32	A:A:Q29	2.71	No	No	0	4	4
849	R:R:E406	R:R:K168	2.7	Yes	No	0	9	8
850	A:A:Y37	B:B:A56	2.67	Yes	No	0	4	7
851	B:B:F335	B:B:S334	2.64	No	No	0	4	4
852	R:R:F230	R:R:S190	2.64	No	No	0	4	5
853	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
854	R:R:F367	R:R:V363	2.62	No	No	0	5	6
855	A:A:D331	A:A:E330	2.6	No	No	0	4	3
856	R:R:E290	R:R:Q293	2.55	No	No	0	6	4
857	R:R:S152	R:R:Y149	2.54	No	Yes	0	9	8
858	A:A:T335	A:A:Y339	2.5	No	Yes	0	4	3
859	R:R:F365	R:R:K381	2.48	No	No	0	7	7
860	R:R:F278	R:R:L277	2.44	Yes	No	0	5	4
861	R:R:F320	R:R:L316	2.44	No	No	0	5	3
862	R:R:F322	R:R:L352	2.44	No	No	0	9	8
863	R:R:F391	R:R:L394	2.44	Yes	No	0	7	5
864	R:R:L198	R:R:R199	2.43	No	No	0	6	4
865	B:B:I123	B:B:Y111	2.42	No	Yes	0	6	4
866	R:R:I315	R:R:Y239	2.42	No	No	0	7	8
867	A:A:E21	A:A:R22	2.33	No	No	0	3	5
868	R:R:F319	R:R:F320	2.14	No	No	0	7	5
869	B:B:G115	B:B:G116	2.11	No	No	0	9	9
870	R:R:G164	R:R:G165	2.11	No	No	0	3	3
871	R:R:R201	R:R:Y202	2.06	No	No	0	4	1
872	R:R:G273	R:R:P275	2.03	No	Yes	0	6	9
873	B:B:C204	B:B:G185	1.96	No	No	0	7	5
874	B:B:C294	B:B:G288	1.96	No	No	0	5	7
875	A:A:A226	A:A:G206	1.95	No	No	0	9	8
876	A:A:A303	A:A:G304	1.95	No	No	0	5	5
877	B:B:A140	B:B:G141	1.95	No	No	0	5	5
878	B:B:A309	B:B:G310	1.95	No	No	0	3	5
879	W:W:P1	W:W:P2	1.95	No	No	0	0	0
880	W:W:P2	W:W:P3	1.95	No	No	0	0	0
881	R:R:A274	R:R:P275	1.87	No	Yes	0	4	9
882	B:B:G77	B:B:S98	1.86	No	No	0	8	8
883	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
884	B:B:G306	B:B:V296	1.84	No	No	0	4	5
885	B:B:G306	B:B:V307	1.84	No	No	0	4	3
886	R:R:G148	R:R:V147	1.84	No	No	0	7	5
887	R:R:G223	R:R:V226	1.84	No	No	0	3	4
888	B:B:G115	B:B:T102	1.82	No	No	0	9	8
889	B:B:G131	B:B:T128	1.82	No	No	0	4	3
890	B:B:G182	B:B:T181	1.82	No	No	0	6	2
891	B:B:G224	B:B:T223	1.82	No	No	0	6	2
892	B:B:A60	B:B:C103	1.81	No	No	0	7	8
893	R:R:A155	R:R:A397	1.79	No	No	0	6	8
894	R:R:A159	R:R:A397	1.79	No	No	0	9	8
895	A:A:P326	A:A:T335	1.75	No	No	0	1	4
896	B:B:P107	B:B:T65	1.75	No	No	0	6	1
897	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
898	B:B:G182	B:B:K209	1.74	No	Yes	0	6	6
899	B:B:C103	B:B:V71	1.71	No	No	0	8	8
900	B:B:A231	B:B:S189	1.71	No	No	0	5	7
901	R:R:G154	R:R:L153	1.71	No	Yes	0	4	6
902	R:R:G164	R:R:L163	1.71	No	Yes	0	3	8
903	R:R:G164	R:R:L169	1.71	No	No	0	3	9
904	R:R:G165	R:R:L166	1.71	No	No	0	3	7
905	R:R:G223	R:R:L197	1.71	No	No	0	3	4
906	R:R:G269	R:R:L268	1.71	No	No	0	4	5
907	A:A:A269	A:A:V248	1.7	No	No	0	9	7
908	A:A:A298	A:A:V334	1.7	No	No	0	4	4
909	B:B:A11	G:G:V16	1.7	No	No	0	5	7
910	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
911	B:B:G131	B:B:N132	1.7	No	No	0	4	3
912	R:R:A227	R:R:V193	1.7	No	No	0	6	5
913	R:R:A283	R:R:V229	1.7	No	No	0	5	6
914	R:R:G359	R:R:N318	1.7	No	Yes	0	9	9
915	A:A:A39	R:R:T257	1.68	No	No	0	5	7
916	A:A:D354	A:A:G355	1.68	No	No	0	3	2
917	R:R:D195	R:R:G196	1.68	No	No	0	7	3
918	R:R:A228	R:R:T296	1.68	No	No	0	5	5
919	B:B:E260	B:B:G224	1.64	No	No	0	6	6
920	R:R:L258	R:R:P259	1.64	No	No	0	6	6
921	R:R:L399	R:R:P356	1.64	No	No	0	8	9
922	A:A:S366	A:A:V367	1.62	No	No	0	9	9
923	R:R:S189	R:R:V193	1.62	No	No	0	4	5
924	R:R:A227	R:R:I194	1.62	No	No	0	6	6
925	A:A:A249	A:A:K293	1.61	No	No	0	8	9
926	B:B:S31	B:B:T34	1.6	No	No	0	1	5
927	R:R:V221	R:R:V292	1.6	No	No	0	4	4
928	R:R:V279	R:R:V280	1.6	No	Yes	0	6	2
929	R:R:V280	R:R:V284	1.6	Yes	No	0	2	4
930	R:R:V363	R:R:V364	1.6	No	No	0	6	6
931	B:B:A11	G:G:L19	1.58	No	Yes	0	5	9
932	R:R:A178	R:R:L160	1.58	No	No	0	7	6
933	R:R:A178	R:R:L163	1.58	No	Yes	0	7	8
934	R:R:A274	W:W:L13	1.58	No	No	0	4	0
935	R:R:C287	R:R:N291	1.57	No	No	0	3	6
936	A:A:A19	B:B:N88	1.56	No	Yes	0	4	7
937	A:A:I207	A:A:V202	1.54	No	No	0	9	6
938	B:B:A21	B:B:D20	1.54	No	No	0	4	2
939	R:R:I162	R:R:V407	1.54	No	No	0	8	9
940	R:R:I270	R:R:V244	1.54	No	No	0	7	8
941	A:A:I56	A:A:T55	1.52	No	No	0	7	9
942	A:A:M221	A:A:V57	1.52	Yes	No	0	8	7
943	B:B:A21	B:B:Q17	1.52	No	No	0	4	4
944	A:A:A14	A:A:E15	1.51	No	No	0	1	5
945	A:A:A18	A:A:E21	1.51	No	No	0	4	3
946	A:A:A39	R:R:E260	1.51	No	No	0	5	6
947	A:A:A316	A:A:E309	1.51	No	No	0	2	4
948	G:G:A39	G:G:E42	1.51	No	No	0	3	1
949	R:R:G196	R:R:R199	1.5	No	No	0	3	4
950	B:B:N125	B:B:S136	1.49	No	No	0	4	4
951	R:R:L197	R:R:V193	1.49	No	No	0	4	5
952	A:A:V20	B:B:N88	1.48	No	Yes	0	3	7
953	A:A:D272	A:A:S275	1.47	Yes	No	0	8	8
954	B:B:D5	B:B:S2	1.47	No	No	0	1	5
955	G:G:L51	G:G:T52	1.47	No	No	0	6	4
956	B:B:N125	B:B:T128	1.46	No	No	0	4	3
957	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
958	A:A:F312	A:A:P313	1.44	Yes	No	0	8	6
959	B:B:E3	B:B:S2	1.44	No	No	0	5	5
960	R:R:K136	R:R:M137	1.44	No	No	0	2	4
961	R:R:E406	R:R:S409	1.44	Yes	No	0	9	4
962	R:R:Q327	R:R:V323	1.43	No	No	0	8	5
963	R:R:E362	R:R:V360	1.43	No	No	0	8	6
964	R:R:Q392	R:R:V360	1.43	No	No	0	9	6
965	A:A:E370	A:A:T369	1.41	No	No	0	4	9
966	G:G:M21	G:G:N24	1.4	No	No	0	1	1
967	A:A:L394	R:R:L347	1.38	Yes	No	16	8	9
968	G:G:A10	G:G:R13	1.38	No	No	0	2	6
969	R:R:L153	R:R:L192	1.38	Yes	No	0	6	7
970	R:R:L333	R:R:L347	1.38	No	No	16	7	9
971	A:A:E209	A:A:I207	1.37	Yes	No	0	9	9
972	A:A:K216	A:A:Q213	1.36	No	No	0	4	3
973	B:B:D20	B:B:N16	1.35	No	No	0	2	1
974	R:R:L377	R:R:Q374	1.33	No	No	0	3	4
975	A:A:D272	A:A:E268	1.3	Yes	No	0	8	9
976	A:A:D323	A:A:E322	1.3	No	No	0	4	1
977	R:R:A182	R:R:W272	1.3	No	Yes	0	4	9
978	B:B:R42	R:R:K422	1.24	No	No	0	2	5
979	R:R:F391	R:R:L151	1.22	Yes	No	0	7	5
980	R:R:F263	R:R:L266	1.22	No	No	0	5	3
981	A:A:L302	A:A:R333	1.21	No	No	0	2	5
982	R:R:E290	R:R:F289	1.17	No	No	0	6	3
983	A:A:E314	A:A:R317	1.16	No	No	0	6	2
984	R:R:W282	W:W:L8	1.14	Yes	No	0	9	0
985	R:R:H340	R:R:Y343	1.09	No	No	0	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Y37	6.8875	4	8	4
2	A:A:H41	9.395	4	0	6
3	A:A:N50	5.96	4	14	9
4	A:A:S51	4.056	5	13	9
5	A:A:K53	5.9325	4	13	9
6	A:A:K203	5.74	4	0	7
7	A:A:F208	5.5625	4	1	5
8	A:A:E209	4.98	4	1	9
9	A:A:F212	8.0925	4	5	9
10	A:A:V214	4.405	4	5	6
11	A:A:F219	6.55857	7	5	8
12	A:A:H220	6.39	4	1	7
13	A:A:M221	4.7925	4	5	8
14	A:A:F222	8.965	4	1	7
15	A:A:Q227	6.66	4	1	9
16	A:A:K233	7.328	5	1	9
17	A:A:W234	6.305	6	1	9
18	A:A:N239	4.9525	4	1	8
19	A:A:F246	4.36	4	0	9
20	A:A:D272	4.5675	4	0	8
21	A:A:F273	5.20833	6	15	9
22	A:A:W277	9.512	5	15	6
23	A:A:W281	11.02	5	1	5
24	A:A:F290	5.5525	4	9	9
25	A:A:Q294	6.155	4	4	6
26	A:A:L297	3.864	5	4	8
27	A:A:Y311	6.1675	4	0	6
28	A:A:F312	5.786	5	0	8
29	A:A:F315	12.8525	4	0	6
30	A:A:Y318	7.09	4	0	6
31	A:A:P321	4.69	5	4	5
32	A:A:Y339	6.70167	6	4	3
33	A:A:R342	7.44	5	4	4
34	A:A:E344	8.8625	4	0	5
35	A:A:F345	7.51	4	0	8
36	A:A:Y358	6.4025	4	0	4
37	A:A:Y360	10.0725	4	0	8
38	A:A:F363	7.65	5	4	5
39	A:A:T364	7.37	4	9	9
40	A:A:D368	6.636	5	9	9
41	A:A:N371	5.25	4	9	9
42	A:A:R374	10.125	4	9	4
43	A:A:F376	7.255	6	5	8
44	A:A:L393	4.24	4	18	8
45	A:A:L394	4.025	4	16	8
46	B:B:L4	5.9175	4	19	4
47	B:B:L7	4.905	4	19	8
48	B:B:I18	3.9875	4	0	7
49	B:B:D27	6.1075	4	0	8
50	B:B:I37	5.88	4	0	2
51	B:B:V40	4.61	4	0	3
52	B:B:H54	10.804	5	8	9
53	B:B:K57	11.586	5	1	9
54	B:B:Y59	11.812	5	1	8
55	B:B:W63	6.52143	7	10	7
56	B:B:L70	5.8	4	10	5
57	B:B:D76	7.314	5	8	9
58	B:B:K78	6.5325	4	8	8
59	B:B:W82	10.702	5	0	9
60	B:B:N88	5.1875	4	0	7
61	B:B:K89	7.49	4	0	9
62	B:B:H91	5.605	4	0	5
63	B:B:W99	9.21	6	1	9
64	B:B:Y111	6.3975	4	0	4
65	B:B:Y124	5.16833	6	21	6
66	B:B:H142	6.67125	8	6	9
67	B:B:Y145	7.38	6	1	8
68	B:B:F151	5.96333	6	0	9
69	B:B:T159	6.155	4	6	9
70	B:B:D163	8.448	5	6	9
71	B:B:W169	9.125	6	6	8
72	B:B:Q176	7.2925	4	6	4
73	B:B:F180	6.612	5	3	7
74	B:B:H183	8.37667	6	3	9
75	B:B:L192	4.2825	4	3	5
76	B:B:F199	5.91	6	3	9
77	B:B:V200	6.53	4	0	6
78	B:B:K209	8.968	5	3	6
79	B:B:L210	6.24	4	0	5
80	B:B:W211	8.59	5	3	8
81	B:B:Q220	7.2575	4	2	7
82	B:B:F222	6.46	4	2	8
83	B:B:H225	9.20714	7	2	9
84	B:B:D228	6	5	1	9
85	B:B:F235	7.69571	7	7	6
86	B:B:P236	6.725	4	7	7
87	B:B:N237	8.075	4	7	5
88	B:B:F241	6.885	4	2	6
89	B:B:D246	5.1275	4	0	9
90	B:B:D247	7.1275	4	2	9
91	B:B:R251	8.395	4	2	8
92	B:B:F253	7.745	6	2	6
93	B:B:D258	8.326	5	2	7
94	B:B:Y264	6.32667	6	7	5
95	B:B:F278	6.725	4	7	7
96	B:B:L285	5.3	4	7	6
97	B:B:Y289	6.39857	7	23	7
98	B:B:D298	7.5	4	20	9
99	B:B:K301	5.0925	4	20	5
100	B:B:H311	8.91	5	25	9
101	B:B:R314	11.19	5	1	8
102	B:B:L318	4.77	4	0	6
103	B:B:W332	11.1933	6	1	9
104	B:B:D333	8.4125	4	25	9
105	B:B:W339	10.2925	4	0	9
106	G:G:L19	2.505	4	0	9
107	G:G:E22	5.435	4	2	9
108	G:G:R27	6.1475	4	2	8
109	G:G:Y40	8.2975	4	7	6
110	G:G:D48	6.25333	6	24	9
111	G:G:V54	4.755	4	11	6
112	G:G:N59	7.0375	4	0	9
113	G:G:F61	5.13	6	0	8
114	R:R:F141	6.3925	4	0	6
115	R:R:Y145	8.9925	4	0	7
116	R:R:Y149	9.4	4	0	8
117	R:R:L153	2.6475	4	0	6
118	R:R:L156	4.7125	4	27	8
119	R:R:L163	2.645	4	0	8
120	R:R:R173	7.9375	4	0	9
121	R:R:F184	9.03833	6	27	8
122	R:R:M231	4.5375	4	0	6
123	R:R:Y233	5.795	4	0	9
124	R:R:W241	10.826	5	28	9
125	R:R:E245	7.43	4	0	9
126	R:R:Y248	8.7625	4	0	8
127	R:R:W272	7.3125	4	28	9
128	R:R:P275	4.11333	6	0	9
129	R:R:F278	6.5075	4	0	5
130	R:R:V280	4.345	4	0	2
131	R:R:W282	5.142	5	29	9
132	R:R:W304	5.01	4	0	6
133	R:R:N318	3.5475	4	0	9
134	R:R:L358	3.708	5	0	9
135	R:R:F383	7.675	4	26	5
136	R:R:F387	5.06	4	26	5
137	R:R:F391	4.83	5	0	7
138	R:R:C401	3.21	4	0	9
139	R:R:E406	6.075	4	17	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:I93	B:B:V133	10.2276	7.68	No	No	0	7	4
2	B:B:I93	B:B:P94	35.0009	3.39	No	No	0	7	5
3	B:B:K78	B:B:P94	35.9054	6.69	Yes	No	0	8	5
4	B:B:D76	B:B:K78	40.4148	6.91	Yes	Yes	8	9	8
5	B:B:D76	B:B:H54	46.6703	5.04	Yes	Yes	8	9	9
6	B:B:H54	B:B:S72	24.685	11.16	Yes	No	0	9	9
7	B:B:S72	B:B:W82	25.1187	6.18	No	Yes	0	9	9
8	B:B:I338	G:G:F61	14.3588	3.77	No	Yes	0	5	8
9	B:B:H54	B:B:I80	24.685	13.26	Yes	No	0	9	8
10	B:B:I80	B:B:W82	25.1187	14.09	No	Yes	0	8	9
11	A:A:F219	A:A:H41	26.6117	9.05	Yes	Yes	0	8	6
12	A:A:F212	A:A:F219	29.1633	12.86	Yes	Yes	5	9	8
13	A:A:F212	A:A:M221	29.5662	3.73	Yes	Yes	5	9	8
14	A:A:L45	A:A:M221	30.8326	8.48	No	Yes	0	8	8
15	A:A:K53	A:A:L45	31.0609	4.23	Yes	No	0	9	8
16	A:A:G47	A:A:K53	24.1242	5.23	No	Yes	13	9	9
17	A:A:G47	A:A:L46	39.7652	3.42	No	No	0	9	8
18	A:A:F246	A:A:L46	40.0409	3.65	Yes	No	0	9	8
19	A:A:D272	A:A:F246	70.3856	4.78	Yes	Yes	0	8	9
20	A:A:D272	A:A:R231	70.9289	10.72	Yes	No	0	8	9
21	A:A:R231	A:A:W234	71.3238	8	No	Yes	0	9	9
22	A:A:W234	B:B:Y145	54.6498	5.79	Yes	Yes	1	9	8
23	B:B:M101	B:B:Y145	92.7563	7.18	No	Yes	1	9	8
24	B:B:M101	B:B:Y59	92.8187	3.59	No	Yes	1	9	8
25	B:B:W332	B:B:Y59	100	10.61	Yes	Yes	1	9	8
26	B:B:S316	B:B:W332	77.0022	6.18	No	Yes	0	9	9
27	B:B:C317	B:B:S316	76.642	3.44	No	No	0	7	9
28	B:B:C317	B:B:M61	76.2852	4.86	No	No	0	7	6
29	B:B:L70	B:B:M61	50.5284	4.24	Yes	No	10	5	6
30	B:B:L70	B:B:W82	49.7499	4.56	Yes	Yes	0	5	9
31	B:B:Q75	B:B:W99	14.419	6.57	No	Yes	1	9	9
32	A:A:H41	A:A:I383	25.0687	6.63	Yes	No	0	6	8
33	B:B:R314	B:B:W332	87.2883	23.99	Yes	Yes	1	8	9
34	A:A:G47	A:A:S51	15.4536	3.71	No	Yes	13	9	9
35	A:A:L297	A:A:Q294	12.3813	5.32	Yes	Yes	4	8	6
36	A:A:L291	A:A:Q294	12.331	5.32	No	Yes	4	8	6
37	A:A:L289	A:A:L291	21.7523	5.54	No	No	0	9	8
38	A:A:F246	A:A:L289	33.5092	3.65	Yes	No	0	9	9
39	A:A:S51	A:A:V247	21.4463	4.85	Yes	No	0	9	7
40	A:A:N292	A:A:V247	20.9857	4.43	No	No	0	9	7
41	B:B:I93	B:B:Y124	24.0503	8.46	No	Yes	0	7	6
42	A:A:Q227	B:B:N119	51.1272	5.28	Yes	No	0	9	9
43	A:A:Q227	B:B:Y145	37.4172	10.15	Yes	Yes	1	9	8
44	A:A:F246	A:A:F273	19.2511	5.36	Yes	Yes	0	9	9
45	A:A:F273	A:A:F345	12.5721	6.43	Yes	Yes	0	9	8
46	A:A:F345	A:A:L289	12.7006	8.53	Yes	No	0	8	9
47	A:A:F345	A:A:L270	21.9674	8.53	Yes	No	0	8	6
48	A:A:E344	A:A:L270	14.8953	3.98	Yes	No	0	5	6
49	A:A:D378	A:A:Y360	11.7748	13.79	No	Yes	0	7	8
50	A:A:F290	A:A:T364	14.2589	9.08	Yes	Yes	9	9	9
51	A:A:N292	A:A:T364	18.715	7.31	No	Yes	0	9	9
52	A:A:H387	R:R:L252	25.9817	19.28	No	No	0	8	8
53	R:R:L252	R:R:Y248	27.7509	5.86	No	Yes	0	8	8
54	R:R:I176	R:R:Y248	28.9648	6.04	No	Yes	0	9	8
55	R:R:E245	R:R:I176	65.1186	5.47	Yes	No	0	9	9
56	A:A:Y391	R:R:E245	39.7097	6.73	No	Yes	0	4	9
57	A:A:Y391	R:R:R173	41.9505	13.38	No	Yes	0	4	9
58	R:R:N174	R:R:R173	80.8445	6.03	No	Yes	0	9	9
59	R:R:L163	R:R:N174	81.0221	4.12	Yes	No	0	8	9
60	R:R:G164	R:R:L163	96.6592	1.71	No	Yes	0	3	8
61	R:R:G164	R:R:G165	97.0715	2.11	No	No	0	3	3
62	R:R:G165	R:R:L166	97.25	1.71	No	No	0	3	7
63	R:R:E410	R:R:L166	98.1356	6.63	No	No	0	8	7
64	R:R:E410	R:R:R413	90.9628	4.65	No	No	0	8	7
65	B:B:F292	R:R:R413	91.093	6.41	No	No	0	4	7
66	B:B:F292	B:B:N313	91.268	4.83	No	No	0	4	7
67	B:B:N313	B:B:W332	91.4789	5.65	No	Yes	0	7	9
68	R:R:E245	R:R:H177	37.9046	13.54	Yes	No	0	9	9
69	R:R:H177	R:R:R173	38.8799	6.77	No	Yes	0	9	9
70	R:R:C401	R:R:L163	33.4353	3.17	Yes	Yes	0	9	8
71	R:R:E245	R:R:L358	24.1758	3.98	Yes	Yes	0	9	9
72	B:B:D290	B:B:R314	86.0006	14.29	No	Yes	0	6	8
73	B:B:C271	B:B:D290	85.7227	6.22	No	No	0	5	6
74	B:B:C271	B:B:Y289	77.1777	4.03	No	Yes	23	5	7
75	B:B:W297	B:B:Y289	59.0559	9.65	No	Yes	0	8	7
76	B:B:W297	B:B:Y264	62.1534	9.65	No	Yes	0	8	5
77	B:B:L252	B:B:Y264	49.2825	5.86	No	Yes	0	7	5
78	B:B:L252	B:B:L261	48.8424	4.15	No	No	0	7	5
79	B:B:L261	G:G:V30	47.0737	2.98	No	No	0	5	8
80	B:B:A26	G:G:V30	44.3949	3.39	No	No	0	3	8
81	B:B:A26	B:B:Q259	43.9455	4.55	No	No	0	3	6
82	B:B:Q259	B:B:R22	43.4952	4.67	No	No	0	6	6
83	B:B:I18	B:B:R22	15.9167	6.26	Yes	No	0	7	6
84	B:B:I18	G:G:L19	12.1824	2.85	Yes	Yes	0	7	9
85	B:B:A11	G:G:L19	10.619	1.58	No	Yes	0	5	9
86	B:B:A11	G:G:V16	10.0961	1.7	No	No	0	5	7
87	B:B:D258	B:B:R22	27.6561	11.91	Yes	No	0	7	6
88	B:B:N340	G:G:F61	12.9904	3.62	No	Yes	0	9	8
89	B:B:N340	G:G:N59	10.4922	10.9	No	Yes	0	9	9
90	B:B:L286	B:B:V327	10.0364	4.47	No	No	0	7	6
91	B:B:L286	B:B:V296	16.2966	4.47	No	No	0	7	5
92	B:B:L284	B:B:V296	17.3731	4.47	No	No	0	5	5
93	B:B:I43	B:B:L284	16.659	5.71	No	No	0	3	5
94	B:B:I43	B:B:V40	15.2283	6.14	No	Yes	0	3	3
95	B:B:D298	B:B:V40	13.0758	8.76	Yes	Yes	0	9	3
96	B:B:N295	B:B:Y289	14.7716	11.63	No	Yes	0	6	7
97	B:B:N295	B:B:V307	17.7414	7.39	No	No	0	6	3
98	B:B:G306	B:B:V307	24.6048	1.84	No	No	0	4	3
99	B:B:L286	B:B:L318	13.2469	4.15	No	Yes	0	7	6
100	B:B:L318	B:B:T329	12.8666	4.42	Yes	No	0	6	8
101	R:R:E410	R:R:S167	17.8071	4.31	No	No	0	8	8
102	B:B:D312	R:R:S167	17.3534	7.36	No	No	0	5	8
103	B:B:D312	B:B:D333	17.0414	5.32	No	Yes	0	5	9
104	B:B:D333	B:B:H311	15.3286	7.56	Yes	Yes	25	9	9
105	B:B:G144	B:B:N119	49.7341	3.39	No	No	0	8	9
106	B:B:D163	B:B:G144	49.268	5.03	Yes	No	0	9	8
107	B:B:D163	B:B:H142	47.3157	3.78	Yes	Yes	6	9	9
108	B:B:H142	B:B:T159	28.6344	6.85	Yes	Yes	6	9	9
109	B:B:C149	B:B:T159	28.9917	3.38	No	Yes	0	8	9
110	B:B:C149	B:B:T102	28.4876	5.07	No	No	0	8	8
111	B:B:C148	B:B:T102	26.9702	3.38	No	No	0	6	8
112	B:B:C148	B:B:R150	25.9544	5.57	No	No	0	6	6
113	B:B:S84	B:B:W63	11.103	4.94	No	Yes	0	5	7
114	B:B:H142	B:B:W169	16.335	7.41	Yes	Yes	6	9	8
115	B:B:I157	B:B:W169	15.5834	3.52	No	Yes	0	7	8
116	B:B:F151	B:B:I157	15.058	13.82	Yes	No	0	9	7
117	B:B:F151	B:B:I123	11.3561	3.77	Yes	No	0	9	6
118	B:B:L192	B:B:R150	24.9351	4.86	Yes	No	0	5	6
119	B:B:F199	B:B:L192	21.3016	3.65	Yes	Yes	3	9	5
120	B:B:F199	B:B:W211	12.8176	10.02	Yes	Yes	3	9	8
121	B:B:D258	B:B:Q220	11.7799	6.53	Yes	Yes	2	7	7
122	B:B:L210	B:B:Q220	11.7441	6.65	Yes	Yes	0	5	7
123	B:B:D258	B:B:F222	13.7634	4.78	Yes	Yes	2	7	8
124	B:B:A287	B:B:Y289	13.0019	4	No	Yes	0	6	7
125	B:B:A287	B:B:V276	12.579	3.39	No	No	0	6	6
126	B:B:L285	B:B:V276	11.8252	4.47	Yes	No	0	6	6
127	B:B:F278	B:B:L285	24.6137	7.31	Yes	Yes	7	7	6
128	B:B:F235	B:B:F278	16.108	9.65	Yes	Yes	7	6	7
129	B:B:L285	B:B:Y264	13.9905	4.69	Yes	Yes	7	6	5
130	R:R:C401	R:R:F402	26.42	2.79	Yes	No	0	9	9
131	R:R:F402	R:R:V398	25.4042	3.93	No	No	0	9	6
132	R:R:L394	R:R:V398	24.3849	2.98	No	No	0	5	6
133	R:R:F391	R:R:L394	23.874	2.44	Yes	No	0	7	5
134	R:R:F387	R:R:F391	11.3561	7.5	Yes	Yes	0	5	7
135	R:R:F391	R:R:S390	10.8239	3.96	Yes	No	0	7	9
136	R:R:S390	R:R:Y149	10.2908	8.9	No	Yes	0	9	8
137	R:R:I176	R:R:W241	55.649	4.7	No	Yes	0	9	9
138	R:R:W241	R:R:W272	49.2351	17.81	Yes	Yes	28	9	9
139	R:R:W272	R:R:Y233	47.8543	6.75	Yes	Yes	0	9	9
140	R:R:V279	R:R:Y233	26.753	3.79	No	Yes	0	6	9
141	R:R:L307	R:R:V279	22.839	4.47	No	No	0	7	6
142	R:R:L307	R:R:W304	22.3601	7.97	No	Yes	0	7	6
143	R:R:P275	R:R:Y233	19.6847	9.74	Yes	Yes	0	9	9
144	R:R:R308	R:R:W304	12.859	3	No	Yes	0	6	6
145	R:R:L358	R:R:N318	11.447	2.75	Yes	Yes	0	9	9
146	R:R:A274	R:R:P275	16.0397	1.87	No	Yes	0	4	9
147	R:R:A274	R:R:F278	14.451	4.16	No	Yes	0	4	5
148	B:B:M61	B:B:W63	25.4059	8.14	No	Yes	10	6	7
149	B:B:S84	G:G:F61	10.6762	5.28	No	Yes	0	5	8
150	B:B:I338	B:B:W63	11.4658	4.7	No	Yes	0	5	7
151	B:B:G306	B:B:V296	22.1975	1.84	No	No	0	4	5
152	B:B:H311	B:B:T329	13.0224	6.85	Yes	No	0	9	8
153	A:A:Q227	A:A:W234	13.757	5.48	Yes	Yes	1	9	9
154	A:A:H387	A:A:I383	24.9407	3.98	No	No	0	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:A274	R:R:F278	4.16	0	No	Yes	4	5	1	1
R:R:L277	W:W:D11	5.43	0	No	No	4	0	1	0
R:R:F278	R:R:P310	14.45	0	Yes	No	5	9	1	2
R:R:F278	W:W:M10	4.98	0	Yes	No	5	0	1	0
R:R:V285	R:R:W282	3.68	0	No	Yes	5	9	2	1
R:R:I306	R:R:W282	8.22	29	No	Yes	8	9	1	1
R:R:W282	W:W:F5	8.02	29	Yes	No	9	0	1	0
R:R:W282	W:W:M10	4.65	29	Yes	No	9	0	1	0
R:R:I306	W:W:F5	6.28	29	No	No	8	0	1	0
R:R:F309	W:W:V9	3.93	0	No	No	4	0	1	0
R:R:I306	W:W:S6	3.1	29	No	No	8	0	1	0
R:R:F309	R:R:P310	2.89	0	No	No	4	9	1	2
R:R:L266	W:W:N15	2.75	0	No	No	3	0	1	0
R:R:F278	R:R:L277	2.44	0	Yes	No	5	4	1	1
R:R:A274	R:R:P275	1.87	0	No	Yes	4	9	1	2
R:R:A274	W:W:L13	1.58	0	No	No	4	0	1	0
R:R:F263	R:R:L266	1.22	0	No	No	5	3	2	1
R:R:W282	W:W:L8	1.14	29	Yes	No	9	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
21.43	Single	8IYX	YL-365	8IYX-GPR34-YL-365
14.29	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
14.29	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
14.29	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
13.33	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
13.33	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
12.00	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
11.76	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
11.11	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
11.11	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
11.11	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
11.11	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
10.71	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
10.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
10.00	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
10.00	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
10.00	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
9.52	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
9.52	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
9.52	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
8.70	Single	5KW2	PubChem 133053953	5KW2-FFA1-PubChem 133053953
8.70	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
8.70	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
8.33	Single	9NS9	Compound 187	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
8.00	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
8.00	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
7.69	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
7.69	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
7.69	Single	8J6Q	Compound 9n	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
7.69	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
7.69	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
7.14	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
7.14	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
7.14	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
7.14	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
7.14	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
7.14	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/β1/γ2
7.14	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
7.14	Single	9CM3	Compound 187	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
7.14	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
6.67	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
6.67	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
6.67	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
6.67	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Single	8Y72	BMS-986122	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
6.67	Single	9JCQ	LPC	9JCQ-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
6.67	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
6.25	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
6.25	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
6.25	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
6.25	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	9IXX	LTD4	9IXX-CysLT₂-LTD4-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Gi1/β1/γ2
5.88	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
5.88	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
5.56	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
5.56	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
5.56	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
5.56	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
5.56	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/β1/γ2
5.56	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
5.56	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.56	Single	8YYX	Leukotriene e4	8YYX-Oxoglutarate-Leukotriene e4-chim(Gi1-CtGq)/β1/γ2
5.56	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
5.56	Single	9CM7	AZ-1729	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
5.56	Single	9IYB	A1D5Q	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
5.56	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
5.56	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
5.26	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
5.26	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
5.26	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
5.26	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
5.26	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
5.26	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
5.26	Single	8XXV	A1D5Q	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
5.26	Single	9CLW	TUG-1375	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
5.26	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
5.26	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
5.26	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
5.26	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
5.26	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.00	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
5.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
5.00	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
5.00	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
5.00	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.00	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
5.00	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
5.00	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
5.00	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
5.00	Single	8Y6W	TUG-1375	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
5.00	Single	9CM3	TUG-1375	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.00	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
5.00	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
5.00	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
4.76	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
4.76	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
4.76	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
4.76	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
4.76	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
4.55	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
4.55	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
4.55	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.55	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.55	Single	9CM7	TUG-1375	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
4.55	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	9NS9	TUG-1375	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
4.35	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
4.35	Single	7QA8	Peptide	7QA8-STE2-Peptide
4.35	Single	7QA8	Peptide	7QA8-STE2-Peptide
4.35	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.35	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.35	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.35	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.35	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.35	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.35	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
4.35	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
4.35	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
4.35	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
4.17	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.17	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
4.00	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.85	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
3.85	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.85	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.85	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.85	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.85	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
3.70	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.57	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
3.45	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
3.45	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
3.33	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
2.70	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
2.70	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2

PDB Summary
PDB	8WG8
Class	B1
SubFamily	Peptide
Type	Glucagon
SubType	Glucagon
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	Peptide
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	2.71
Date	2024-03-06
D.O.I.	doi.org/10.1038/s41421-024-00649-0

Net Summary
I_min	3.39
Number of Linked Nodes	861
Number of Links	985
Number of Hubs	139
Number of Links mediated by Hubs	530
Number of Communities	29
Number of Nodes involved in Communities	173
Number of Links involved in Communities	230

Path Summary
Number Of Nodes in MetaPath	155
Number Of Links MetaPath	154
Number of Shortest Paths	689661
Length Of Smallest Path	3
Average Path Length	24.3139
Length of Longest Path	55
Minimum Path Strength	1.385
Average Path Strength	6.43439
Maximum Path Strength	22.355
Minimum Path Correlation	0.7
Average Path Correlation	0.974479
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.85714
Average % Of Corr. Nodes	53.4166
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.3498
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye
Gene Ontology	Biological Process	• positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • intracellular anatomical structure • cytoplasm • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • organelle • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • synapse • cell junction • cell body • protein binding • binding • G-protein beta-subunit binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • cellular process • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • glucagon receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • amide binding • peptide hormone binding • hormone binding • GTPase regulator activity • enzyme regulator activity • guanyl-nucleotide exchange factor activity • nucleoside-triphosphatase regulator activity • molecular function regulator activity • multicellular organismal process • system process • circulatory system process • regulation of blood pressure • regulation of biological quality • blood circulation • regulation of biosynthetic process • positive regulation of biological process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • regulation of metabolic process • positive regulation of cellular process • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • carbohydrate metabolic process • energy derivation by oxidation of organic compounds • glycogen metabolic process • primary metabolic process • regulation of generation of precursor metabolites and energy • generation of precursor metabolites and energy • regulation of polysaccharide metabolic process • regulation of primary metabolic process • glucan metabolic process • polysaccharide metabolic process • energy reserve metabolic process • regulation of glycogen metabolic process • regulation of carbohydrate metabolic process • cellular response to nutrient levels • response to nutrient levels • cellular response to stress • response to stress • response to starvation • cellular response to starvation • cell surface receptor signaling pathway • response to nutrient • chemical homeostasis • homeostatic process • glucose homeostasis • carbohydrate homeostasis • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • G protein activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • D2 dopamine receptor binding • adenylate cyclase inhibitor activity • molecular function inhibitor activity • cyclase inhibitor activity • enzyme inhibitor activity • magnesium ion binding • GDP binding • G protein-coupled serotonin receptor binding • developmental process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • cell-cell signaling • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • cell division • leukocyte migration • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of small molecule metabolic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • negative regulation of transport • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • negative regulation of peptide hormone secretion • negative regulation of establishment of protein localization • negative regulation of protein secretion • negative regulation of signaling • negative regulation of cell communication • negative regulation of peptide secretion • negative regulation of cellular process • negative regulation of protein localization • negative regulation of insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • lysosomal membrane • lysosome • ciliary basal body
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8WG8_Chain_A L S A E D K A A V E R S K M I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I V K Q M R I V K T S G I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V A S S S Y N R L Q E A L N D F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C S V D T E N A R R V F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8WG8_Chain_B S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8WG8_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P47871
Sequence	>8WG8_Chain_R A K M Y S S F Q V M Y T V G Y S L S L G A L L L A L A I L G G L S K L H C T R N A I H A N L F A S F V L K A S S V L V I D G L L R T R Y A V A G C R V A A V F M Q Y G I V A N Y C W L L V E G L Y L H N L L G L A T L P E R S F F S L Y L G I G W G A P M L F V V P W A V V K C L F E N V Q C W T S N F W W I L R F P V F L A I L I N F F I F V R I V Q L L V A K L R A R Q M H H T D Y K F R L A K S T L T L I P L L G V H E V V F A F V Q G T L R S A K L F F D L F L S S F Q G L L V A V L Y C F L N K E V Q S E L R R R W H R W R L G K V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	doi.org/10.1038/s41586-019-1902-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	doi.org/10.1038/s41467-021-24058-z
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	doi.org/10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	doi.org/10.1038/s41467-021-24058-z
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	doi.org/10.1038/nature22378
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.2	2020-03-18	doi.org/10.1038/s41467-020-14934-5
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.8	2019-11-13	doi.org/10.1107/S2052252519013496
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	3.1	2019-11-13	doi.org/10.1107/S2052252519013496
	8WG8	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide	chim(NtGi1-Gs)/β1/γ2	2.71	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WG8 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide		2.71	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	doi.org/10.1038/nature22378
	5XEZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3	2017-05-24	doi.org/10.1038/nature22363
	5XF1	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3.19	2017-05-24	doi.org/10.1038/nature22363
	5EE7	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	MK0893	-	2.5	2016-04-20	doi.org/10.1038/nature17414
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	LSN3556672	chim(NtGi1-Gs)/β1/γ2	3.08	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RBT (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	LSN3556672		3.08	2022-04-13	doi.org/10.1073/pnas.2116506119
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	doi.org/10.1016/j.apsb.2024.09.002
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	doi.org/10.1038/s41589-020-0589-7
	7CZ5	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-	Gs/β1/γ2	2.6	2020-11-18	doi.org/10.1038/s41467-020-18945-0
	7CZ5 (No Gprot)	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-		2.6	2020-11-18	doi.org/10.1038/s41467-020-18945-0
	7V9M	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-	Gs/β1/γ2	3.29	2021-10-20	doi.org/10.1073/pnas.2106606118
	7V9M (No Gprot)	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-		3.29	2021-10-20	doi.org/10.1073/pnas.2106606118
	7V9L	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2022-04-06	doi.org/10.1073/pnas.2106606118
	7V9L (No Gprot)	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-		2.6	2022-04-06	doi.org/10.1073/pnas.2106606118
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	2.86	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		2.86	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/β1/γ2	3.1	2022-02-23	doi.org/10.1038/s41467-022-28683-0
	7FIN (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-		3.1	2022-02-23	doi.org/10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7FIY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VAB (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-		3.2	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/β1/γ2	3.24	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		3.24	2022-04-13	doi.org/10.1073/pnas.2116506119
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.23	2023-10-18	doi.org/10.1073/pnas.2306145120
	8ITL (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.23	2023-10-18	doi.org/10.1073/pnas.2306145120
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.13	2023-10-18	doi.org/10.1073/pnas.2306145120
	8ITM (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.13	2023-10-18	doi.org/10.1073/pnas.2306145120
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/β1/γ2	2.98	2021-08-04	doi.org/10.7554/eLife.68719
	7DTY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		2.98	2021-08-04	doi.org/10.7554/eLife.68719
	8YW4	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ2	3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW4 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-		3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	doi.org/10.1016/j.apsb.2024.09.002
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	doi.org/10.1016/j.bbrc.2021.09.016
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	doi.org/10.1016/j.celrep.2021.109374
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	doi.org/10.1016/j.molcel.2020.09.020
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	doi.org/10.1016/j.str.2021.04.008
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	doi.org/10.1021/acs.jmedchem.1c01856
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	doi.org/10.1021/jacs.4c12808
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	doi.org/10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	doi.org/10.1038/nature22394
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	doi.org/10.1038/nature22800
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	doi.org/10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	doi.org/10.1038/nature25773
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	doi.org/10.1038/s41421-024-00649-0
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	doi.org/10.1038/s41422-020-0384-8
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	doi.org/10.1038/s41467-021-27760-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	doi.org/10.1038/s41467-022-28683-0
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	doi.org/10.1038/s41589-021-00945-w
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	doi.org/10.1073/pnas.2014879117
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	doi.org/10.1073/pnas.2116506119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	doi.org/10.1073/pnas.2200155119
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	doi.org/10.1073/pnas.2303696120
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	9EBN	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBN (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.44	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-	Gs/β1/γ2	3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (ACPC18)	-		3.13	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	9EBQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.16	2025-03-26	doi.org/10.1073/pnas.2407574122
	8YWF	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ2	2.74	2025-04-16	To be published
	8YWF (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.74	2025-04-16	To be published
	9BYO	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-	Gs/β1/γ2	2.31	2025-06-11	To be published
	9BYO (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-3	-		2.31	2025-06-11	To be published
	9C0K	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	2.72	2025-06-11	To be published
	9C0K (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		2.72	2025-06-11	To be published
	7D68	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-	Gs/β1/γ2	3	2020-12-16	doi.org/10.1038/s41422-020-00442-0
	7D68 (No Gprot)	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-		3	2020-12-16	doi.org/10.1038/s41422-020-00442-0
	8FU6	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/β1/γ2	2.9	2023-04-12	doi.org/10.1016/j.cell.2023.02.028
	8FU6 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-		2.9	2023-04-12	doi.org/10.1016/j.cell.2023.02.028
	4L6R	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	-	3.3	2013-07-24	doi.org/10.1038/nature12393
	5YQZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon analogue	-	-	3	2018-01-17	doi.org/10.1038/nature25153
	7V35	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3.5	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	7V35 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-		3.5	2022-03-02	doi.org/10.1038/s41467-022-28683-0
	8JRU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	Arrestin2	3.5	2023-08-16	doi.org/10.1038/s41586-023-06420-x
	8JRV	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Arrestin2	3.3	2023-08-16	doi.org/10.1038/s41586-023-06420-x
	8JIT	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-	Gs/β1/γ2	2.91	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIT (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-		2.91	2023-09-06	doi.org/10.1073/pnas.2303696120
	8JIQ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-	Gs/β1/γ2	3.4	2023-09-13	doi.org/10.1073/pnas.2303696120
	8JIQ (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-		3.4	2023-09-13	doi.org/10.1073/pnas.2303696120
	8JIU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-	Gs/β1/γ2	2.76	2023-09-13	doi.org/10.1073/pnas.2303696120
	8JIU (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-		2.76	2023-09-13	doi.org/10.1073/pnas.2303696120
	6WHC	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-	Gs/β1/γ2	3.4	2020-05-27	doi.org/10.1074/jbc.RA120.013793
	6WHC (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-		3.4	2020-05-27	doi.org/10.1074/jbc.RA120.013793
	6LMK	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gs/β1/γ2	3.7	2020-04-01	doi.org/10.1126/science.aaz5346
	6LMK (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-		3.7	2020-04-01	doi.org/10.1126/science.aaz5346
	6LML	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gi1/β1/γ1	3.9	2020-04-01	doi.org/10.1126/science.aaz5346
	6LML (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-		3.9	2020-04-01	doi.org/10.1126/science.aaz5346
	6WPW	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/β1/γ2	3.1	2020-08-12	doi.org/10.1126/science.aba3373
	6WPW (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-		3.1	2020-08-12	doi.org/10.1126/science.aba3373
	8YW5	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.84	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW5 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Retatrutide	-		2.84	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	7D3S	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	2.9	2020-11-04	doi.org/10.1016/j.bbrc.2020.08.042
	7D3S (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		2.9	2020-11-04	doi.org/10.1016/j.bbrc.2020.08.042
	6WI9	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	4.3	2020-08-12	doi.org/10.1038/s41467-020-17791-4
	6WI9 (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		4.3	2020-08-12	doi.org/10.1038/s41467-020-17791-4
	6WZG	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	2.3	2020-08-12	doi.org/10.1038/s41467-020-17791-4
	6WZG (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		2.3	2020-08-12	doi.org/10.1038/s41467-020-17791-4

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