psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:P5	R:R:Q6	7.9	No	No	0	7	4
2	R:R:P5	R:R:S69	3.56	No	No	0	7	4
3	R:R:F9	R:R:V13	6.55	No	No	0	6	6
4	R:R:F9	R:R:L67	19.49	No	No	0	6	4
5	R:R:K62	R:R:Y12	16.72	No	Yes	0	7	9
6	R:R:L262	R:R:Y12	3.52	No	Yes	0	5	9
7	R:R:I263	R:R:Y12	8.46	No	Yes	0	6	9
8	R:R:A15	R:R:W267	6.48	No	No	0	7	4
9	R:R:F16	R:R:T56	3.89	No	No	0	6	6
10	R:R:F16	R:R:L59	3.65	No	No	0	6	9
11	R:R:F16	R:R:P60	7.22	No	No	0	6	9
12	R:R:L18	R:R:V270	4.47	No	No	0	6	6
13	R:R:G19	R:R:V269	3.68	No	Yes	0	8	7
14	R:R:F20	R:R:P21	4.33	No	No	0	5	5
15	R:R:F20	R:R:V24	3.93	No	No	0	5	3
16	R:R:D52	R:R:N23	13.46	Yes	No	0	9	9
17	R:R:N23	R:R:P273	13.03	No	No	0	9	9
18	R:R:G49	R:R:I27	3.53	No	Yes	0	8	7
19	R:R:P40	R:R:T39	3.5	Yes	No	0	7	7
20	R:R:P40	R:R:Y114	5.56	Yes	Yes	2	7	6
21	R:R:P40	R:R:R118	5.76	Yes	No	2	7	8
22	R:R:P40	R:R:S123	3.56	Yes	Yes	2	7	8
23	R:R:P40	W:W:?1	5.47	Yes	Yes	2	7	0
24	R:R:R104	R:R:S41	9.22	No	No	0	9	7
25	R:R:S123	R:R:V43	4.85	Yes	No	0	8	7
26	R:R:V43	R:R:W124	17.16	No	No	0	7	4
27	R:R:A99	R:R:Y44	8.01	No	Yes	2	6	7
28	R:R:L100	R:R:Y44	3.52	No	Yes	0	8	7
29	R:R:S123	R:R:Y44	7.63	Yes	Yes	2	8	7
30	R:R:V126	R:R:Y44	8.83	No	Yes	2	5	7
31	R:R:Y44	W:W:?1	10.93	Yes	Yes	2	7	0
32	R:R:A45	R:R:T276	5.03	No	No	0	7	7
33	R:R:F96	R:R:N47	9.67	Yes	No	3	6	9
34	R:R:C127	R:R:N47	12.6	No	No	3	7	9
35	R:R:D52	R:R:L48	4.07	Yes	Yes	3	9	9
36	R:R:F96	R:R:L48	4.87	Yes	Yes	3	6	9
37	R:R:L48	R:R:L97	5.54	Yes	Yes	3	9	8
38	R:R:L48	R:R:N272	9.61	Yes	Yes	3	9	9
39	R:R:F96	R:R:S51	5.28	Yes	No	0	6	8
40	R:R:D52	R:R:V269	4.38	Yes	Yes	0	9	7
41	R:R:D52	R:R:N272	10.77	Yes	Yes	3	9	9
42	R:R:H86	R:R:L55	5.14	Yes	Yes	0	6	7
43	R:R:L55	R:R:P89	4.93	Yes	No	0	7	8
44	R:R:L55	R:R:L90	4.15	Yes	No	0	7	7
45	R:R:L55	R:R:V269	4.47	Yes	Yes	0	7	7
46	R:R:T56	R:R:V269	4.76	No	Yes	0	6	7
47	R:R:F82	R:R:S58	3.96	Yes	No	0	5	7
48	R:R:H86	R:R:S58	8.37	Yes	No	0	6	7
49	R:R:L61	R:R:W72	6.83	No	Yes	1	6	9
50	R:R:F82	R:R:L61	12.18	Yes	No	1	5	6
51	R:R:E65	R:R:K62	9.45	No	No	0	7	7
52	R:R:H86	R:R:K62	6.55	Yes	No	0	6	7
53	R:R:E65	R:R:L171	5.3	No	Yes	0	7	5
54	R:R:E172	R:R:E65	5.07	Yes	No	0	6	7
55	R:R:E172	R:R:G70	6.55	Yes	No	0	6	6
56	R:R:P73	R:R:W72	6.76	No	Yes	1	4	9
57	R:R:L74	R:R:W72	10.25	No	Yes	1	7	9
58	R:R:C79	R:R:W72	6.53	No	Yes	1	9	9
59	R:R:F82	R:R:W72	10.02	Yes	Yes	1	5	9
60	R:R:C170	R:R:W72	10.45	No	Yes	1	9	9
61	R:R:L74	R:R:P73	4.93	No	No	1	7	4
62	R:R:L74	R:R:L78	5.54	No	No	0	7	5
63	R:R:L78	R:R:P75	4.93	No	No	0	5	8
64	R:R:C79	R:R:P80	3.77	No	No	0	9	7
65	R:R:C170	R:R:C79	7.28	No	No	1	9	9
66	R:R:A146	R:R:P80	3.74	No	No	0	3	7
67	R:R:F82	R:R:L171	3.65	Yes	Yes	1	5	5
68	R:R:A83	R:R:F142	5.55	No	No	0	6	4
69	R:R:F87	R:R:H86	4.53	Yes	Yes	1	6	6
70	R:R:H86	R:R:L171	3.86	Yes	Yes	1	6	5
71	R:R:F87	R:R:Y91	4.13	Yes	Yes	0	6	8
72	R:R:F87	R:R:L171	3.65	Yes	Yes	1	6	5
73	R:R:F87	R:R:Y240	9.28	Yes	Yes	1	6	8
74	R:R:L138	R:R:Y91	5.86	No	Yes	0	6	8
75	R:R:L190	R:R:Y91	5.86	No	Yes	0	6	8
76	R:R:N241	R:R:Y91	10.47	No	Yes	0	9	8
77	R:R:A92	R:R:F96	4.16	No	Yes	3	6	6
78	R:R:A92	R:R:W131	3.89	No	No	3	6	9
79	R:R:G95	W:W:?1	5.69	No	Yes	0	5	0
80	R:R:C127	R:R:F96	4.19	No	Yes	3	7	6
81	R:R:F96	R:R:I130	7.54	Yes	No	0	6	6
82	R:R:F96	R:R:W131	11.02	Yes	No	3	6	9
83	R:R:L97	R:R:N272	10.98	Yes	Yes	3	8	9
84	R:R:A99	W:W:?1	5.24	No	Yes	2	6	0
85	R:R:S101	R:R:T198	6.4	No	No	0	9	8
86	R:R:C201	R:R:S101	5.16	No	No	0	7	9
87	R:R:A102	W:W:?1	8.39	No	Yes	0	6	0
88	R:R:R104	R:R:V225	9.15	No	No	0	9	7
89	R:R:L106	R:R:Y105	3.52	No	Yes	2	7	7
90	R:R:A109	R:R:Y105	5.34	No	Yes	2	8	7
91	R:R:F110	R:R:Y105	4.13	No	Yes	2	6	7
92	R:R:F200	R:R:Y105	4.13	No	Yes	0	4	7
93	R:R:C201	R:R:Y105	6.72	No	Yes	0	7	7
94	R:R:G204	R:R:Y105	4.35	No	Yes	0	4	7
95	R:R:L106	R:R:Y114	9.38	No	Yes	2	7	6
96	R:R:L106	W:W:?1	3.69	No	Yes	2	7	0
97	R:R:G107	R:R:Y114	4.35	No	Yes	0	8	6
98	R:R:A109	R:R:F110	5.55	No	No	2	8	6
99	R:R:R118	R:R:Y114	10.29	No	Yes	2	8	6
100	R:R:Y114	W:W:?1	7.02	Yes	Yes	2	6	0
101	R:R:Q115	R:R:R118	5.84	No	No	0	5	8
102	R:R:Q115	R:R:R218	5.84	No	No	0	5	5
103	R:R:R119	R:R:Y122	8.23	No	No	0	5	3
104	R:R:S123	W:W:?1	4	Yes	Yes	2	8	0
105	R:R:V126	W:W:?1	8.93	No	Yes	2	5	0
106	R:R:I130	W:W:?1	6.65	No	Yes	0	6	0
107	R:R:L133	W:W:?1	3.69	No	Yes	0	5	0
108	R:R:H137	R:R:S185	6.97	Yes	No	0	5	5
109	R:R:H137	R:R:L186	10.29	Yes	No	0	5	6
110	R:R:H137	R:R:L189	6.43	Yes	No	0	5	5
111	R:R:H137	R:R:L190	10.29	Yes	No	0	5	6
112	R:R:L138	R:R:L186	5.54	No	No	0	6	6
113	R:R:L186	R:R:V141	11.92	No	No	0	6	5
114	R:R:F142	R:R:R183	11.76	No	No	0	4	6
115	R:R:E172	R:R:K259	8.1	Yes	No	0	6	3
116	R:R:S247	R:R:W174	3.71	No	Yes	0	6	4
117	R:R:L253	R:R:W174	4.56	No	Yes	0	3	4
118	R:R:G255	R:R:W174	4.22	No	Yes	0	5	4
119	R:R:R258	R:R:W174	5	Yes	Yes	0	7	4
120	R:R:D175	R:R:R183	21.44	Yes	No	1	6	6
121	R:R:D175	R:R:N244	4.04	Yes	No	1	6	7
122	R:R:D175	R:R:F248	4.78	Yes	Yes	1	6	5
123	R:R:P176	R:R:S178	3.56	No	No	0	1	1
124	R:R:A179	R:R:P176	3.74	No	No	0	4	1
125	R:R:G180	R:R:P181	4.06	No	No	0	3	4
126	R:R:F248	R:R:G180	10.54	Yes	No	0	5	3
127	R:R:F248	R:R:R183	4.28	Yes	No	1	5	6
128	R:R:F184	R:R:L188	4.87	No	No	0	4	4
129	R:R:F184	R:R:V245	5.24	No	No	0	4	5
130	R:R:N241	R:R:S187	8.94	No	No	0	9	5
131	R:R:F191	R:R:F192	11.79	Yes	No	0	9	4
132	R:R:F191	R:R:L195	7.31	Yes	No	0	9	6
133	R:R:F191	R:R:V237	5.24	Yes	No	0	9	8
134	R:R:F191	R:R:G238	4.52	Yes	No	0	9	4
135	R:R:F191	R:R:N241	13.29	Yes	No	0	9	9
136	R:R:L193	W:W:?1	6.45	No	Yes	0	4	0
137	R:R:P194	W:W:?1	14.21	No	Yes	0	9	0
138	R:R:I197	W:W:?1	4.75	No	Yes	0	6	0
139	R:R:L233	R:R:T198	4.42	No	No	0	9	8
140	R:R:F202	R:R:L206	10.96	Yes	No	0	8	5
141	R:R:F202	R:R:G227	6.02	Yes	No	0	8	4
142	R:R:F202	R:R:L230	4.87	Yes	No	0	8	8
143	R:R:R207	R:R:R211	4.26	No	No	0	4	4
144	R:R:H216	R:R:L209	3.86	No	No	0	2	8
145	R:R:L209	R:R:L220	4.15	No	No	0	8	4
146	R:R:L214	R:R:S212	12.01	No	No	0	3	5
147	R:R:L220	R:R:W224	4.56	No	No	0	4	5
148	R:R:G228	R:R:V275	3.68	No	No	0	5	7
149	R:R:L271	R:R:T232	7.37	No	No	0	6	6
150	R:R:L233	R:R:V237	4.47	No	No	0	9	8
151	R:R:C236	R:R:L271	4.76	No	No	0	8	6
152	R:R:G238	R:R:P239	4.06	No	No	0	4	9
153	R:R:P239	R:R:T264	6.99	No	No	0	9	5
154	R:R:N244	R:R:Y240	13.96	No	Yes	1	7	8
155	R:R:R258	R:R:Y240	8.23	Yes	Yes	1	7	8
156	R:R:L262	R:R:Y240	7.03	No	Yes	0	5	8
157	R:R:R258	R:R:S243	3.95	Yes	No	0	7	5
158	R:R:N244	R:R:R258	7.23	No	Yes	1	7	7
159	R:R:F248	R:R:S247	7.93	Yes	No	0	5	6
160	R:R:L249	R:R:Y250	4.69	No	No	0	4	2
161	R:R:N252	R:R:Y250	4.65	No	No	0	1	2
162	R:R:V270	R:R:W267	8.58	No	No	0	6	4
163	R:R:N272	R:R:S268	5.96	Yes	No	0	9	9
164	R:R:T276	R:R:Y278	7.49	No	No	0	7	7
165	R:R:C236	R:R:S268	3.44	No	No	0	8	9
166	R:R:L46	R:R:W124	3.42	No	No	0	6	4
167	R:R:G94	R:R:L97	3.42	No	Yes	0	8	8
168	R:R:A182	R:R:V141	3.39	No	No	0	4	5
169	R:R:A173	R:R:V169	3.39	No	No	0	5	5
170	R:R:L3	R:R:P4	3.28	No	No	0	7	6
171	R:R:L7	R:R:P4	3.28	No	No	0	7	6
172	R:R:L54	R:R:P89	3.28	No	No	0	7	8
173	R:R:L214	R:R:P111	3.28	No	No	0	3	9
174	R:R:D175	R:R:P176	3.22	Yes	No	0	6	1
175	R:R:R217	R:R:R221	3.2	No	No	0	3	7
176	R:R:T232	R:R:V275	3.17	No	No	0	6	7
177	R:R:A30	R:R:L46	3.15	No	No	0	6	6
178	R:R:A266	R:R:L59	3.15	No	No	0	6	9
179	R:R:A88	R:R:L135	3.15	No	No	0	5	3
180	R:R:A229	R:R:L97	3.15	No	Yes	0	8	8
181	R:R:A103	W:W:?1	3.15	No	Yes	0	8	0
182	R:R:Y122	W:W:?1	3.12	No	Yes	0	3	0
183	R:R:I263	R:R:S8	3.1	No	No	0	6	3
184	R:R:K219	R:R:S212	3.06	No	No	0	6	5
185	R:R:A179	R:R:E145	3.02	No	No	0	4	4
186	R:R:L100	R:R:S41	3	No	No	0	8	7
187	R:R:L230	R:R:T198	2.95	No	No	0	8	8
188	R:R:L260	R:R:T264	2.95	No	No	0	3	5
189	R:R:G29	R:R:Y278	2.9	No	No	0	7	7
190	R:R:I263	R:R:L11	2.85	No	No	0	6	5
191	R:R:I27	R:R:L53	2.85	Yes	No	0	7	7
192	R:R:K219	R:R:L209	2.82	No	No	0	6	8
193	R:R:G254	R:R:W257	2.81	No	No	0	6	5
194	R:R:A63	R:R:F9	2.77	No	No	0	7	6
195	R:R:A222	R:R:R104	2.77	No	No	0	8	9
196	R:R:L195	R:R:L234	2.77	No	No	0	6	5
197	R:R:A226	R:R:F202	2.77	No	Yes	0	7	8
198	R:R:L231	R:R:L235	2.77	No	No	0	5	5
199	R:R:L53	R:R:N23	2.75	No	No	0	7	9
200	R:R:A66	R:R:Y12	2.67	No	Yes	0	6	9
201	R:R:R207	R:R:V203	2.62	No	No	0	4	3
202	R:R:A14	R:R:W267	2.59	No	No	0	4	4
203	R:R:F20	R:R:T56	2.59	No	No	0	5	6
204	R:R:R218	R:R:T215	2.59	No	No	0	5	3
205	R:R:V134	R:R:Y91	2.52	No	Yes	0	7	8
206	R:R:S256	R:R:W257	2.47	No	No	0	1	5
207	R:R:L253	R:R:W257	2.28	No	No	0	3	5
208	R:R:G93	R:R:G94	2.11	No	No	0	9	8
209	R:R:A129	W:W:?1	2.1	No	Yes	0	3	0
210	R:R:G261	R:R:P239	2.03	No	No	0	6	9
211	R:R:C236	R:R:G265	1.96	No	No	0	8	8
212	R:R:P4	R:R:P5	1.95	No	No	0	6	7
213	R:R:A98	R:R:G95	1.95	No	No	0	7	5
214	R:R:A128	R:R:G125	1.95	No	No	0	4	1
215	R:R:A26	R:R:P273	1.87	No	No	0	9	9
216	R:R:A88	R:R:P89	1.87	No	No	0	5	8
217	R:R:G10	R:R:V13	1.84	No	No	0	5	6
218	R:R:G139	R:R:V84	1.84	No	No	0	4	6
219	R:R:G277	R:R:T276	1.82	No	No	0	4	7
220	R:R:A108	R:R:C205	1.81	No	Yes	0	8	7
221	R:R:A222	R:R:C205	1.81	No	Yes	0	8	7
222	R:R:A223	R:R:C205	1.81	No	Yes	0	5	7
223	R:R:A226	R:R:C205	1.81	No	Yes	0	7	7
224	R:R:A30	R:R:A45	1.79	No	No	0	6	7
225	R:R:A68	R:R:A71	1.79	No	No	0	3	4
226	R:R:A108	R:R:A208	1.79	No	No	0	8	5
227	R:R:A109	R:R:A208	1.79	No	No	0	8	5
228	R:R:P73	R:R:V64	1.77	No	No	0	4	4
229	R:R:G19	R:R:L18	1.71	No	No	0	8	6
230	R:R:G139	R:R:L138	1.71	No	No	0	4	6
231	R:R:A42	R:R:T39	1.68	No	No	0	7	7
232	R:R:L22	R:R:P273	1.64	No	No	0	7	9
233	R:R:C50	R:R:I27	1.64	No	Yes	0	4	7
234	R:R:L112	R:R:P111	1.64	No	No	0	6	9
235	R:R:N252	R:R:P251	1.63	No	No	0	1	2
236	R:R:F117	W:W:?1	1.62	No	Yes	0	4	0
237	R:R:A108	R:R:K219	1.61	No	No	0	8	6
238	R:R:A199	R:R:L230	1.58	No	No	0	4	8
239	R:R:I27	R:R:T31	1.52	Yes	No	0	7	1
240	R:R:L78	R:R:S77	1.5	No	No	0	5	1
241	R:R:G204	R:R:R207	1.5	No	No	0	4	4
242	R:R:P120	R:R:R119	1.44	No	No	0	4	5
243	R:R:E172	R:R:V169	1.43	Yes	No	0	6	5
244	R:R:C121	R:R:R119	1.39	No	No	0	4	5
245	R:R:L11	R:R:L7	1.38	No	No	0	5	7
246	R:R:L188	R:R:L189	1.38	No	No	0	4	5
247	R:R:A63	R:R:Y12	1.33	No	Yes	0	7	9
248	R:R:R217	R:R:T215	1.29	No	No	0	3	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y12	6.54	5	0	9
2	R:R:I27	2.385	4	0	7
3	R:R:P40	4.77	5	2	7
4	R:R:Y44	7.784	5	2	7
5	R:R:L48	6.0225	4	3	9
6	R:R:D52	8.17	4	3	9
7	R:R:L55	4.6725	4	0	7
8	R:R:W72	8.47333	6	1	9
9	R:R:F82	7.4525	4	1	5
10	R:R:H86	5.69	5	1	6
11	R:R:F87	5.3975	4	1	6
12	R:R:Y91	5.768	5	0	8
13	R:R:F96	6.67571	7	3	6
14	R:R:L97	5.7725	4	3	8
15	R:R:Y105	4.69833	6	2	7
16	R:R:Y114	7.32	5	2	6
17	R:R:S123	5.01	4	2	8
18	R:R:H137	8.495	4	0	5
19	R:R:L171	4.115	4	1	5
20	R:R:E172	5.2875	4	0	6
21	R:R:W174	4.3725	4	0	4
22	R:R:D175	8.37	4	1	6
23	R:R:F191	8.43	5	0	9
24	R:R:F202	6.155	4	0	8
25	R:R:C205	1.81	4	0	7
26	R:R:Y240	9.625	4	1	8
27	R:R:F248	6.8825	4	1	5
28	R:R:R258	6.1025	4	1	7
29	R:R:V269	4.3225	4	0	7
30	R:R:N272	9.33	4	3	9
31	W:W:?1	5.83889	18	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:A63	R:R:F9	10.9032	2.77	No	No	0	7	6
2	R:R:A63	R:R:Y12	13.5875	1.33	No	Yes	0	7	9
3	R:R:I263	R:R:Y12	23.8087	8.46	No	Yes	0	6	9
4	R:R:I263	R:R:L11	18.8861	2.85	No	No	0	6	5
5	R:R:L11	R:R:L7	16.2543	1.38	No	No	0	5	7
6	R:R:L7	R:R:P4	13.5875	3.28	No	No	0	7	6
7	R:R:K62	R:R:Y12	31.9402	16.72	No	Yes	0	7	9
8	R:R:L262	R:R:Y12	10.9994	3.52	No	Yes	0	5	9
9	R:R:G19	R:R:L18	10.7458	1.71	No	No	0	8	6
10	R:R:G19	R:R:V269	12.8443	3.68	No	Yes	0	8	7
11	R:R:L55	R:R:V269	100	4.47	Yes	Yes	0	7	7
12	R:R:H86	R:R:L55	99.8426	5.14	Yes	Yes	0	6	7
13	R:R:H86	R:R:K62	36.3907	6.55	Yes	No	0	6	7
14	R:R:T56	R:R:V269	16.6477	4.76	No	Yes	0	6	7
15	R:R:D52	R:R:V269	98.4524	4.38	Yes	Yes	0	9	7
16	R:R:D52	R:R:N23	18.956	13.46	Yes	No	0	9	9
17	R:R:L53	R:R:N23	10.7021	2.75	No	No	0	7	9
18	R:R:P40	W:W:?1	13.7973	5.47	Yes	Yes	2	7	0
19	R:R:I130	W:W:?1	81.8396	6.65	No	Yes	0	6	0
20	R:R:F96	R:R:I130	82.3205	7.54	Yes	No	0	6	6
21	R:R:F96	R:R:L48	85.783	4.87	Yes	Yes	3	6	9
22	R:R:D52	R:R:L48	81.4899	4.07	Yes	Yes	3	9	9
23	R:R:Y114	W:W:?1	11.218	7.02	Yes	Yes	2	6	0
24	R:R:R118	R:R:Y114	11.83	10.29	No	Yes	2	8	6
25	R:R:S123	W:W:?1	17.8281	4	Yes	Yes	2	8	0
26	R:R:Y44	W:W:?1	10.3261	10.93	Yes	Yes	2	7	0
27	R:R:L100	R:R:Y44	10.2474	3.52	No	Yes	0	8	7
28	R:R:S123	R:R:V43	18.3789	4.85	Yes	No	0	8	7
29	R:R:V43	R:R:W124	16.4991	17.16	No	No	0	7	4
30	R:R:A30	R:R:A45	10.4398	1.79	No	No	0	6	7
31	R:R:A30	R:R:L46	12.477	3.15	No	No	0	6	6
32	R:R:L46	R:R:W124	14.4968	3.42	No	No	0	6	4
33	R:R:D52	R:R:N272	14.8553	10.77	Yes	Yes	3	9	9
34	R:R:F82	R:R:S58	14.6367	3.96	Yes	No	0	5	7
35	R:R:H86	R:R:S58	16.5341	8.37	Yes	No	0	6	7
36	R:R:F82	R:R:L171	25.8722	3.65	Yes	Yes	1	5	5
37	R:R:H86	R:R:L171	21.2381	3.86	Yes	Yes	1	6	5
38	R:R:E65	R:R:L171	12.5033	5.3	No	Yes	0	7	5
39	R:R:F82	R:R:W72	35.0616	10.02	Yes	Yes	1	5	9
40	R:R:E172	R:R:E65	14.5318	5.07	Yes	No	0	6	7
41	R:R:L74	R:R:W72	13.2465	10.25	No	Yes	1	7	9
42	R:R:L74	R:R:L78	10.0114	5.54	No	No	0	7	5
43	R:R:D175	R:R:N244	19.5156	4.04	Yes	No	1	6	7
44	R:R:N244	R:R:Y240	20.5911	13.96	No	Yes	1	7	8
45	R:R:L262	R:R:Y240	11.83	7.03	No	Yes	0	5	8
46	R:R:F87	R:R:H86	50.118	4.53	Yes	Yes	1	6	6
47	R:R:F87	R:R:Y240	42.686	9.28	Yes	Yes	1	6	8
48	R:R:F87	R:R:Y91	57.4714	4.13	Yes	Yes	0	6	8
49	R:R:L138	R:R:Y91	11.8213	5.86	No	Yes	0	6	8
50	R:R:L190	R:R:Y91	14.287	5.86	No	Yes	0	6	8
51	R:R:N241	R:R:Y91	41.7242	10.47	No	Yes	0	9	8
52	R:R:F191	R:R:N241	40.8062	13.29	Yes	No	0	9	9
53	R:R:F191	R:R:V237	35.4464	5.24	Yes	No	0	9	8
54	R:R:L233	R:R:V237	34.8605	4.47	No	No	0	9	8
55	R:R:L233	R:R:T198	34.4496	4.42	No	No	0	9	8
56	R:R:S101	R:R:T198	18.0205	6.4	No	No	0	9	8
57	R:R:C201	R:R:S101	17.8893	5.16	No	No	0	7	9
58	R:R:L106	W:W:?1	31.1533	3.69	No	Yes	2	7	0
59	R:R:L106	R:R:Y105	35.5863	3.52	No	Yes	2	7	7
60	R:R:A109	R:R:Y105	17.0237	5.34	No	Yes	2	8	7
61	R:R:Q115	R:R:R118	17.8543	5.84	No	No	0	5	8
62	R:R:Q115	R:R:R218	14.1733	5.84	No	No	0	5	5
63	R:R:H137	R:R:L190	12.2235	10.29	Yes	No	0	5	6
64	R:R:R258	R:R:Y240	15.2313	8.23	Yes	Yes	1	7	8
65	R:R:R258	R:R:W174	12.2847	5	Yes	Yes	0	7	4
66	R:R:F202	R:R:L230	20.1889	4.87	Yes	No	0	8	8
67	R:R:L230	R:R:T198	23.5114	2.95	No	No	0	8	8
68	R:R:A108	R:R:K219	19.4282	1.61	No	No	0	8	6
69	R:R:A108	R:R:C205	13.0366	1.81	No	Yes	0	8	7
70	R:R:A226	R:R:C205	15.7821	1.81	No	Yes	0	7	7
71	R:R:A226	R:R:F202	15.5198	2.77	No	Yes	0	7	8
72	R:R:A108	R:R:A208	13.4476	1.79	No	No	0	8	5
73	R:R:A109	R:R:A208	15.31	1.79	No	No	0	8	5
74	R:R:C236	R:R:S268	12.6344	3.44	No	No	0	8	9
75	R:R:N272	R:R:S268	14.6804	5.96	Yes	No	0	9	9
76	R:R:R218	R:R:T215	11.1917	2.59	No	No	0	5	3
77	R:R:F87	R:R:L171	13.2902	3.65	Yes	Yes	1	6	5
78	R:R:C201	R:R:Y105	17.8106	6.72	No	Yes	0	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:P40	R:R:T39	3.5	2	Yes	No	7	7	1	2
R:R:P40	R:R:Y114	5.56	2	Yes	Yes	7	6	1	1
R:R:P40	R:R:R118	5.76	2	Yes	No	7	8	1	2
R:R:P40	R:R:S123	3.56	2	Yes	Yes	7	8	1	1
R:R:P40	W:W:?1	5.47	2	Yes	Yes	7	0	1	0
R:R:S123	R:R:V43	4.85	2	Yes	No	8	7	1	2
R:R:A99	R:R:Y44	8.01	2	No	Yes	6	7	1	1
R:R:L100	R:R:Y44	3.52	0	No	Yes	8	7	2	1
R:R:S123	R:R:Y44	7.63	2	Yes	Yes	8	7	1	1
R:R:V126	R:R:Y44	8.83	2	No	Yes	5	7	1	1
R:R:Y44	W:W:?1	10.93	2	Yes	Yes	7	0	1	0
R:R:G95	W:W:?1	5.69	0	No	Yes	5	0	1	0
R:R:F96	R:R:I130	7.54	3	Yes	No	6	6	2	1
R:R:A99	W:W:?1	5.24	2	No	Yes	6	0	1	0
R:R:A102	W:W:?1	8.39	0	No	Yes	6	0	1	0
R:R:L106	R:R:Y105	3.52	2	No	Yes	7	7	1	2
R:R:L106	R:R:Y114	9.38	2	No	Yes	7	6	1	1
R:R:L106	W:W:?1	3.69	2	No	Yes	7	0	1	0
R:R:G107	R:R:Y114	4.35	0	No	Yes	8	6	2	1
R:R:R118	R:R:Y114	10.29	2	No	Yes	8	6	2	1
R:R:Y114	W:W:?1	7.02	2	Yes	Yes	6	0	1	0
R:R:R119	R:R:Y122	8.23	0	No	No	5	3	2	1
R:R:S123	W:W:?1	4	2	Yes	Yes	8	0	1	0
R:R:V126	W:W:?1	8.93	2	No	Yes	5	0	1	0
R:R:I130	W:W:?1	6.65	0	No	Yes	6	0	1	0
R:R:L133	W:W:?1	3.69	0	No	Yes	5	0	1	0
R:R:L193	W:W:?1	6.45	0	No	Yes	4	0	1	0
R:R:P194	W:W:?1	14.21	0	No	Yes	9	0	1	0
R:R:I197	W:W:?1	4.75	0	No	Yes	6	0	1	0
R:R:A103	W:W:?1	3.15	0	No	Yes	8	0	1	0
R:R:Y122	W:W:?1	3.12	0	No	Yes	3	0	1	0
R:R:A129	W:W:?1	2.1	0	No	Yes	3	0	1	0
R:R:A98	R:R:G95	1.95	0	No	No	7	5	2	1
R:R:F117	W:W:?1	1.62	0	No	Yes	4	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
61.90	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
44.44	Single	9K1C	DHA	9K1C-FFA1-DHA-Gi1/β1/γ2
42.86	Single	9IYB	A1D5Q	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
40.91	Single	8XXV	A1D5Q	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
40.00	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
39.13	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
38.46	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
38.46	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
38.10	Single	9K1D	Cholesterol	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
33.33	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
33.33	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
32.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
31.82	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
30.00	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
30.00	Single	8K9L	VV9	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
29.17	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/β1/γ2
28.57	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
28.57	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/β1/γ2
27.78	Single	5XSZ	Glyceryl-mono-oleate	5XSZ-LPA₆-Glyceryl-mono-oleate
25.00	Single	6OBA	GTPL11074	6OBA-β₂-S-Alprenolol-GTPL11074
25.00	Single	8XXU	A1D5Q	8XXU-DP₂-A1D5Q-Gi1/β1/γ2
21.05	Single	9K1D	Cholesterol	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
20.00	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/β1/γ2
18.18	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
18.18	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
17.39	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
16.67	Single	8IYX	YL-365	8IYX-GPR34-YL-365
8.70	Single	8WG8	Peptide	8WG8-Glucagon-Peptide-chim(NtGi1-Gs)/β1/γ2
8.00	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
6.45	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.25	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
5.41	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
5.13	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
5.00	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
4.55	Single	9GE2	Cholesterol	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
4.00	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
3.45	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
3.33	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
3.33	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
3.33	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
3.33	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
3.23	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
3.23	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
3.23	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
3.23	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
3.03	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
2.94	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
2.94	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
2.94	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2

PDB Summary
PDB	5KW2
Class	A
SubFamily	Lipid
Type	Free Fatty Acid
SubType	FFA1
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	PubChem 133053953
Protein Partners	-
PDB Resolution	2.76
Date	2018-05-02
D.O.I.	10.1038/s41467-017-01240-w

Net Summary
I_min	3.5
Number of Linked Nodes	227
Number of Links	248
Number of Hubs	31
Number of Links mediated by Hubs	126
Number of Communities	3
Number of Nodes involved in Communities	37
Number of Links involved in Communities	52

Path Summary
Number Of Nodes in MetaPath	79
Number Of Links MetaPath	78
Number of Shortest Paths	28314
Length Of Smallest Path	3
Average Path Length	11.5829
Length of Longest Path	26
Minimum Path Strength	1.415
Average Path Strength	5.70408
Maximum Path Strength	13.245
Minimum Path Correlation	0.7
Average Path Correlation	0.906027
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.7619
Average % Of Corr. Nodes	47.5399
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.6193
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• biological process involved in interspecies interaction between organisms • response to stimulus • response to other organism • defense response • response to external stimulus • response to biotic stimulus • defense response to bacterium • defense response to other organism • response to stress • response to bacterium • response to external biotic stimulus • carbohydrate derivative catabolic process • catabolic process • peptidoglycan catabolic process • glycosaminoglycan metabolic process • carbohydrate derivative metabolic process • aminoglycan catabolic process • macromolecule catabolic process • glycosaminoglycan catabolic process • aminoglycan metabolic process • peptidoglycan metabolic process • metabolic process • cellular process • macromolecule metabolic process • symbiont-mediated cytolysis of host cell • viral life cycle • disruption of cell in another organism • cytolysis • biological process involved in interaction with host • biological process involved in symbiotic interaction • viral release from host cell by cytolysis • exit from host cell • viral process • cytolysis in another organism • viral release from host cell • disruption of anatomical structure in another organism • symbiont-mediated killing of host cell • killing of cells of another organism • cell killing • cell wall organization or biogenesis • cell wall macromolecule catabolic process • cell wall macromolecule metabolic process • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • regulation of localization • regulation of calcium ion transport • positive regulation of calcium ion transport • transport • regulation of transport • regulation of monoatomic ion transport • positive regulation of biological process • establishment of localization • calcium ion transport • metal ion transport • localization • positive regulation of transport • positive regulation of monoatomic ion transport • monoatomic ion transport • monoatomic cation transport • regulation of metal ion transport • response to lipid • response to fatty acid • response to chemical • response to oxygen-containing compound • multicellular organismal process • interleukin-1 production • negative regulation of biological process • regulation of interleukin-1 beta production • negative regulation of interleukin-1 beta production • negative regulation of interleukin-1 production • regulation of cytokine production • cytokine production • negative regulation of cellular process • regulation of multicellular organismal process • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • regulation of interleukin-1 production • negative regulation of metabolic process • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • negative regulation of gene expression • biosynthetic process • negative regulation of biosynthetic process • interleukin-1 beta production • negative regulation of macromolecule biosynthetic process • regulation of macromolecule biosynthetic process • negative regulation of multicellular organismal process • regulation of metabolic process • protein localization • positive regulation of cell communication • establishment of protein localization • nitrogen compound transport • positive regulation of establishment of protein localization • cellular macromolecule localization • positive regulation of insulin secretion • regulation of peptide hormone secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • regulation of protein secretion • regulation of secretion • positive regulation of protein localization • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • peptide secretion • regulation of secretion by cell • secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • amide transport • signal release • positive regulation of cellular process • positive regulation of peptide secretion • regulation of signaling • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • positive regulation of protein secretion • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • positive regulation of signaling • chemical homeostasis • homeostatic process • glucose homeostasis • carbohydrate homeostasis • ligand-gated ion channel signaling pathway • host cellular component • host intracellular part • cellular anatomical structure • host cell cytoplasm • host cell part • host intracellular region • cell periphery • plasma membrane • membrane
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• G protein-coupled receptor-like
SCOP2	Family Identifier	• G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	6XQ
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	6XQ
Name	(3~{S})-3-cyclopropyl-3-[2-[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxy-phenyl]piperidin-4-yl]-1-benzofuran-6-yl]propanoic acid
Synonyms
Identifier
Formula	C38 H45 N3 O5
Molecular Weight	623.781
SMILES
PubChem	133053953
Formal Charge	0
Total Atoms	91
Total Chiral Atoms	1
Total Bonds	96
Total Aromatic Bonds	22


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O14842
Sequence	>5KW2_Chain_R L P P Q L S F G L Y V A A F A L G F P L N V L A I R G A T A T P S A V Y A L N L G C S D L L L T V S L P L K A V E A L A S G A W P L P A S L C P V F A V A H F A P L Y A G G G F L A A L S A A R Y L G A A F P L G Y Q A F R R P C Y S W G V C A A I W A L V L C H L G L V F G L E A P V C L E A W D P A S A G P A R F S L S L L L F F L P L A I T A F C F V G C L R A L A R S L T H R R K L R A A W V A G G A L L T L L L C V G P Y N A S N V A S F L Y P N L G G S W R K L G L I T G A W S V V L N P L V T G Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9K1C	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	-	DHA	Gi1/β1/γ2	3.2	2024-12-11	10.1016/j.celrep.2024.115024
	9K1C (No Gprot)	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	-	DHA		3.2	2024-12-11	10.1016/j.celrep.2024.115024
	8T3V	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	Docosa-4,7,10,13,16,19-Hexaenoic acid	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.39	2024-01-24	10.1126/sciadv.adj2384
	8T3V (No Gprot)	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	Docosa-4,7,10,13,16,19-Hexaenoic acid	-		3.39	2024-01-24	10.1126/sciadv.adj2384
	8EJK	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	TAK-875	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	3.4	2023-05-24	10.1073/pnas.2219569120
	8EJK (No Gprot)	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	TAK-875	-		3.4	2023-05-24	10.1073/pnas.2219569120
	8EJC	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	TAK-875	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	3	2023-05-24	10.1073/pnas.2219569120
	8EJC (No Gprot)	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	TAK-875	-		3	2023-05-24	10.1073/pnas.2219569120
	8EIT	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	Doconexent	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.8	2023-05-24	10.1073/pnas.2219569120
	8EIT (No Gprot)	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	Doconexent	-		2.8	2023-05-24	10.1073/pnas.2219569120
	5KW2	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	-	PubChem 133053953	-	2.76	2018-05-02	10.1038/s41467-017-01240-w
	5TZY	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	-	MK8666; PubChem 127053597	-	3.22	2017-06-07	10.1038/nsmb.3417
	5TZR	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	-	MK8666	-	2.2	2017-06-07	10.1038/nsmb.3417
	4PHU	A	Lipid	Free Fatty Acid	FFA1	Homo sapiens	-	Fasiglifam	-	2.33	2014-07-16	10.1038/nature13494

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