psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:A12	A:A:K10	3.21	No	No	0	4	3
2	A:A:K10	A:A:V13	4.55	No	No	0	3	3
3	A:A:V13	B:B:N88	7.39	No	No	0	3	7
4	A:A:R15	B:B:H91	5.64	No	Yes	0	5	5
5	A:A:D20	A:A:S16	4.42	No	No	4	6	7
6	A:A:S16	B:B:N88	5.96	No	No	0	7	7
7	A:A:S16	B:B:K89	4.59	No	Yes	4	7	9
8	A:A:I19	B:B:K89	4.36	Yes	Yes	0	9	9
9	A:A:I19	B:B:A92	3.25	Yes	No	0	9	6
10	A:A:D20	B:B:K89	9.68	No	Yes	4	6	9
11	A:A:D26	B:B:K78	9.68	No	No	0	5	8
12	A:A:E33	A:A:H195	13.54	No	No	0	6	4
13	A:A:E33	A:A:K197	14.85	No	No	0	6	6
14	A:A:L36	A:A:V34	4.47	Yes	Yes	8	7	5
15	A:A:F196	A:A:V34	17.04	Yes	Yes	8	7	5
16	A:A:V339	A:A:V34	4.81	Yes	Yes	8	8	5
17	A:A:F199	A:A:K35	6.2	Yes	No	0	5	9
18	A:A:F196	A:A:L36	3.65	Yes	Yes	8	7	7
19	A:A:I222	A:A:L36	7.14	No	Yes	0	7	7
20	A:A:L36	A:A:V339	4.47	Yes	Yes	8	7	8
21	A:A:L37	A:A:L39	6.92	No	No	0	9	9
22	A:A:F215	A:A:L37	4.87	Yes	No	0	9	9
23	A:A:K46	A:A:L38	5.64	Yes	No	10	9	8
24	A:A:D200	A:A:L38	5.43	No	No	10	9	8
25	A:A:I253	A:A:L39	5.71	No	No	0	8	9
26	A:A:F223	A:A:G40	4.52	No	No	0	9	9
27	A:A:A41	A:A:S44	3.42	No	No	0	7	9
28	A:A:D42	A:A:R242	4.76	No	Yes	0	8	9
29	A:A:K46	A:A:S44	3.06	Yes	No	0	9	9
30	A:A:G45	A:A:N269	5.09	No	Yes	0	9	9
31	A:A:D200	A:A:K46	9.68	No	Yes	10	9	9
32	A:A:C224	A:A:K46	4.85	No	Yes	10	7	9
33	A:A:K51	A:A:S47	3.06	No	No	0	9	9
34	A:A:C224	A:A:I49	4.91	No	Yes	10	7	7
35	A:A:F267	A:A:I49	7.54	Yes	Yes	10	9	7
36	A:A:I49	A:A:N269	8.5	Yes	Yes	10	7	9
37	A:A:I49	A:A:T324	4.56	Yes	Yes	10	7	9
38	A:A:I49	A:A:N331	4.25	Yes	No	10	7	8
39	A:A:K51	A:A:V50	3.04	No	No	0	9	6
40	A:A:T187	A:A:V50	4.76	No	No	17	6	6
41	A:A:M198	A:A:V50	3.04	No	No	17	7	6
42	A:A:D328	A:A:Q52	5.22	No	No	0	9	9
43	A:A:G183	A:A:T182	3.64	No	No	0	9	7
44	A:A:G183	B:B:N119	3.39	No	No	0	9	9
45	A:A:I184	A:A:V201	3.07	Yes	Yes	1	9	9
46	A:A:F215	A:A:I184	3.77	Yes	Yes	1	9	9
47	A:A:I184	B:B:W99	8.22	Yes	Yes	1	9	9
48	A:A:I184	B:B:L117	4.28	Yes	Yes	1	9	9
49	A:A:E186	A:A:F199	9.33	No	Yes	1	9	5
50	A:A:E186	B:B:W99	10.9	No	Yes	1	9	9
51	A:A:M198	A:A:T187	4.52	No	No	17	7	6
52	A:A:H188	A:A:H195	9.55	No	No	0	3	4
53	A:A:H188	A:A:K197	10.48	No	No	0	3	6
54	A:A:F189	A:A:F196	11.79	No	Yes	0	9	7
55	A:A:F189	A:A:M198	3.73	No	No	0	9	7
56	A:A:H195	A:A:T190	6.85	No	No	0	4	3
57	A:A:F191	A:A:K192	11.17	Yes	No	8	5	4
58	A:A:A332	A:A:F191	4.16	No	Yes	0	7	5
59	A:A:F191	A:A:Q333	8.2	Yes	No	0	5	5
60	A:A:F191	A:A:F336	7.5	Yes	Yes	8	5	8
61	A:A:F336	A:A:K192	9.93	Yes	No	8	8	4
62	A:A:F196	A:A:L194	8.53	Yes	No	0	7	4
63	A:A:L194	R:R:F690	8.53	No	Yes	0	4	8
64	A:A:F196	A:A:F336	3.22	Yes	Yes	8	7	8
65	A:A:F196	A:A:V339	3.93	Yes	Yes	8	7	8
66	A:A:F199	A:A:K197	4.96	Yes	No	0	5	6
67	A:A:F199	A:A:F215	8.57	Yes	Yes	1	5	9
68	A:A:F199	B:B:W99	14.03	Yes	Yes	1	5	9
69	A:A:V201	A:A:W211	3.68	Yes	Yes	1	9	9
70	A:A:F215	A:A:V201	5.24	Yes	Yes	1	9	9
71	A:A:Q204	A:A:S206	5.78	Yes	Yes	1	9	8
72	A:A:Q204	A:A:W211	6.57	Yes	Yes	1	9	9
73	A:A:Q204	B:B:L117	3.99	Yes	Yes	1	9	9
74	A:A:Q204	B:B:N119	5.28	Yes	No	0	9	9
75	A:A:Q204	B:B:Y145	5.64	Yes	Yes	1	9	8
76	A:A:S206	A:A:W211	6.18	Yes	Yes	1	8	9
77	A:A:S206	B:B:Y145	5.09	Yes	Yes	1	8	8
78	A:A:S206	B:B:D186	4.42	Yes	Yes	1	8	9
79	A:A:E207	A:A:K209	12.15	Yes	No	1	9	8
80	A:A:E207	A:A:K210	5.4	Yes	Yes	1	9	9
81	A:A:E207	B:B:D186	5.2	Yes	Yes	1	9	9
82	A:A:E207	B:B:C204	4.56	Yes	Yes	1	9	7
83	A:A:E207	B:B:D228	5.2	Yes	Yes	1	9	9
84	A:A:I212	A:A:R208	6.26	No	No	0	8	9
85	A:A:R208	A:A:S252	5.27	No	No	0	9	7
86	A:A:I253	A:A:R208	5.01	No	No	0	8	9
87	A:A:K209	A:A:K210	7.18	No	Yes	1	8	9
88	A:A:K209	B:B:D228	5.53	No	Yes	1	8	9
89	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
90	A:A:K210	B:B:M188	11.52	Yes	Yes	1	9	8
91	A:A:K210	B:B:C204	4.85	Yes	Yes	1	9	7
92	A:A:K210	B:B:D228	9.68	Yes	Yes	1	9	9
93	A:A:K210	B:B:N230	4.2	Yes	No	1	9	9
94	A:A:K210	B:B:D246	4.15	Yes	Yes	1	9	9
95	A:A:W211	B:B:L117	5.69	Yes	Yes	1	9	9
96	A:A:W211	B:B:Y145	8.68	Yes	Yes	1	9	8
97	A:A:H213	A:A:W258	9.52	No	Yes	0	8	5
98	A:A:H213	B:B:Y59	7.62	No	Yes	1	8	8
99	A:A:H213	B:B:W332	6.35	No	Yes	1	8	9
100	A:A:C214	A:A:F215	4.19	No	Yes	1	7	9
101	A:A:C214	B:B:Y59	4.03	No	Yes	1	7	8
102	A:A:C214	B:B:Q75	4.58	No	No	1	7	9
103	A:A:F215	B:B:W99	13.03	Yes	Yes	1	9	9
104	A:A:E216	A:A:W258	8.72	No	Yes	0	7	5
105	A:A:E216	B:B:K57	6.75	No	No	0	7	9
106	A:A:A220	A:A:I265	3.25	No	No	0	8	8
107	A:A:F259	A:A:I221	6.28	No	No	18	9	8
108	A:A:I221	A:A:T262	4.56	No	No	18	8	7
109	A:A:I222	A:A:I265	5.89	No	No	0	7	8
110	A:A:F223	A:A:L249	6.09	No	No	0	9	9
111	A:A:F223	A:A:F250	11.79	No	Yes	0	9	9
112	A:A:C224	A:A:N269	3.15	No	Yes	10	7	9
113	A:A:S246	A:A:V225	4.85	No	No	2	9	7
114	A:A:L268	A:A:V225	4.47	No	No	2	8	7
115	A:A:F307	A:A:V225	10.49	Yes	No	2	8	7
116	A:A:D226	A:A:K270	6.91	No	No	0	8	9
117	A:A:F274	A:A:L227	8.53	Yes	No	0	9	7
118	A:A:I303	A:A:L227	4.28	No	No	0	7	7
119	A:A:K270	A:A:S228	6.12	No	No	19	9	9
120	A:A:L273	A:A:S228	4.5	No	No	19	6	9
121	A:A:D229	A:A:R242	4.76	No	Yes	0	8	9
122	A:A:F274	A:A:Y230	5.16	Yes	Yes	2	9	8
123	A:A:K277	A:A:Y230	14.33	No	Yes	0	9	8
124	A:A:I278	A:A:Y230	3.63	Yes	Yes	2	6	8
125	A:A:L283	A:A:Y230	7.03	No	Yes	2	7	8
126	A:A:C286	A:A:Y230	5.38	No	Yes	0	6	8
127	A:A:Y230	A:A:Y287	5.96	Yes	Yes	2	8	7
128	A:A:E245	A:A:R242	6.98	No	Yes	0	9	9
129	A:A:M243	A:A:Y287	4.79	No	Yes	0	8	7
130	A:A:F307	A:A:M243	3.73	Yes	No	0	8	8
131	A:A:H244	A:A:Y287	5.44	No	Yes	0	4	7
132	A:A:F307	A:A:S246	3.96	Yes	No	2	8	9
133	A:A:F307	A:A:M247	6.22	Yes	No	0	8	6
134	A:A:F250	A:A:I264	6.28	Yes	Yes	2	9	6
135	A:A:F250	A:A:L266	3.65	Yes	No	2	9	9
136	A:A:F250	A:A:F307	6.43	Yes	Yes	2	9	8
137	A:A:F250	A:A:L310	3.65	Yes	No	0	9	4
138	A:A:D251	A:A:N255	9.42	No	Yes	0	5	8
139	A:A:C254	A:A:N255	6.3	No	Yes	0	5	8
140	A:A:C254	A:A:K317	3.23	No	Yes	0	5	7
141	A:A:K312	A:A:N255	8.39	No	Yes	0	5	8
142	A:A:N255	A:A:R313	3.62	Yes	Yes	0	8	4
143	A:A:F259	A:A:N256	6.04	No	No	0	9	8
144	A:A:K257	A:A:W258	18.57	No	Yes	0	4	5
145	A:A:W258	B:B:R314	4	Yes	No	0	5	8
146	A:A:F259	A:A:T262	6.49	No	No	18	9	7
147	A:A:D261	A:A:T260	7.23	No	No	0	4	3
148	A:A:R313	A:A:T260	7.76	Yes	No	0	4	3
149	A:A:D261	A:A:T316	4.34	No	No	0	4	3
150	A:A:S263	A:A:Y320	5.09	No	Yes	2	7	7
151	A:A:S263	A:A:V342	6.46	No	No	2	7	7
152	A:A:I264	A:A:L266	4.28	Yes	No	2	6	9
153	A:A:I264	A:A:K317	5.82	Yes	Yes	0	6	7
154	A:A:I264	A:A:I319	7.36	Yes	No	0	6	5
155	A:A:A338	A:A:I265	4.87	No	No	0	6	8
156	A:A:L266	A:A:T321	5.9	No	No	2	9	5
157	A:A:F267	A:A:N269	3.62	Yes	Yes	10	9	9
158	A:A:F267	A:A:T324	3.89	Yes	Yes	10	9	9
159	A:A:F267	A:A:N331	4.83	Yes	No	10	9	8
160	A:A:F267	A:A:F334	5.36	Yes	Yes	0	9	3
161	A:A:F267	A:A:I335	5.02	Yes	No	0	9	8
162	A:A:L268	A:A:Q304	3.99	No	Yes	2	8	5
163	A:A:F323	A:A:L268	8.53	Yes	No	2	4	8
164	A:A:N269	A:A:T324	7.31	Yes	Yes	10	9	9
165	A:A:K270	A:A:L273	11.28	No	No	19	9	6
166	A:A:K271	A:A:Y296	10.75	No	Yes	2	5	4
167	A:A:F323	A:A:K271	6.2	Yes	No	2	4	5
168	A:A:C325	A:A:D272	4.67	No	No	0	7	9
169	A:A:F274	A:A:I278	8.79	Yes	Yes	2	9	6
170	A:A:F274	A:A:Y296	4.13	Yes	Yes	2	9	4
171	A:A:E275	A:A:E276	3.81	No	No	0	5	5
172	A:A:E275	A:A:Y296	12.35	No	Yes	0	5	4
173	A:A:I285	A:A:P282	10.16	No	No	0	3	5
174	A:A:N294	A:A:P282	3.26	No	No	0	3	5
175	A:A:L283	A:A:Y287	4.69	No	Yes	2	7	7
176	A:A:A291	A:A:L283	4.73	No	No	0	3	7
177	A:A:A291	A:A:T284	3.36	No	No	0	3	4
178	A:A:E289	A:A:Y287	6.73	No	Yes	0	6	7
179	A:A:E289	A:A:Y302	4.49	No	No	0	6	6
180	A:A:E298	A:A:G292	4.91	No	No	0	4	7
181	A:A:S293	A:A:T295	4.8	No	No	0	3	5
182	A:A:E298	A:A:S293	5.75	No	No	0	4	3
183	A:A:E297	A:A:T295	9.88	No	No	0	4	5
184	A:A:A300	A:A:Y296	9.34	No	Yes	0	5	4
185	A:A:F323	A:A:Y296	3.09	Yes	Yes	2	4	4
186	A:A:Q306	A:A:Y302	14.65	No	No	0	5	6
187	A:A:E308	A:A:Q304	7.65	No	Yes	2	3	5
188	A:A:Q304	A:A:T321	11.34	Yes	No	2	5	5
189	A:A:F323	A:A:Q304	7.03	Yes	Yes	2	4	5
190	A:A:C305	A:A:D309	4.67	No	No	0	3	4
191	A:A:E308	A:A:T321	4.23	No	No	2	3	5
192	A:A:E308	R:R:R780	4.65	No	No	2	3	3
193	A:A:K317	A:A:N311	13.99	Yes	No	0	7	8
194	A:A:I319	A:A:N311	7.08	No	No	0	5	8
195	A:A:R313	A:A:T316	3.88	Yes	No	0	4	3
196	A:A:K317	A:A:R313	3.71	Yes	Yes	0	7	4
197	A:A:D315	A:A:T316	8.67	No	No	0	3	3
198	A:A:E318	A:A:Y320	8.98	No	Yes	2	4	7
199	A:A:E318	R:R:R777	6.98	No	Yes	2	4	5
200	A:A:E318	R:R:R780	9.3	No	No	2	4	3
201	A:A:A338	A:A:Y320	5.34	No	Yes	0	6	7
202	A:A:D341	A:A:Y320	5.75	No	Yes	0	8	7
203	A:A:V342	A:A:Y320	3.79	No	Yes	2	7	7
204	A:A:Y320	R:R:V774	5.05	Yes	No	2	7	5
205	A:A:Y320	R:R:R777	11.32	Yes	Yes	2	7	5
206	A:A:H322	A:A:K330	6.55	No	No	0	9	4
207	A:A:F334	A:A:H322	24.89	Yes	No	0	3	9
208	A:A:H322	R:R:E776	8.62	No	No	0	9	5
209	A:A:F323	R:R:E776	9.33	Yes	No	0	4	5
210	A:A:N331	A:A:T324	8.77	No	Yes	10	8	9
211	A:A:T327	A:A:T329	3.14	No	No	0	8	9
212	A:A:K330	A:A:T327	4.5	No	No	0	4	8
213	A:A:D337	A:A:Q333	9.14	No	No	0	4	5
214	A:A:F334	R:R:V774	5.24	Yes	No	0	3	5
215	A:A:F334	R:R:G775	4.52	Yes	No	0	3	6
216	A:A:F336	R:R:F690	3.22	Yes	Yes	8	8	8
217	A:A:T340	R:R:F690	6.49	No	Yes	0	6	8
218	A:A:D341	A:A:K345	8.3	No	No	0	8	5
219	A:A:N346	A:A:V342	4.43	No	No	0	4	7
220	A:A:I343	R:R:V689	3.07	No	No	8	7	9
221	A:A:I343	R:R:F690	3.77	No	Yes	8	7	8
222	A:A:I344	R:R:V689	6.14	No	No	0	6	9
223	A:A:F354	A:A:K345	6.2	Yes	No	0	5	5
224	A:A:N347	R:R:R685	6.03	No	Yes	0	8	8
225	A:A:L348	A:A:L353	6.92	No	No	0	9	7
226	A:A:F354	A:A:L348	8.53	Yes	No	0	5	9
227	A:A:F354	A:A:K349	6.2	Yes	No	0	5	5
228	A:A:D350	R:R:S617	8.83	No	No	3	4	8
229	A:A:D350	R:R:T619	5.78	No	No	3	4	8
230	A:A:C351	R:R:L682	4.76	No	No	0	4	9
231	A:A:L353	R:R:V765	5.96	No	No	0	7	9
232	A:A:L353	R:R:S792	7.51	No	No	0	7	8
233	A:A:F354	R:R:R788	4.28	Yes	No	0	5	7
234	B:B:L4	B:B:R8	4.86	No	No	0	4	3
235	B:B:L4	G:G:I9	9.99	No	No	0	4	2
236	B:B:L7	B:B:Q6	5.32	No	No	0	8	1
237	B:B:L7	G:G:A12	3.15	No	No	0	8	5
238	B:B:E10	B:B:Q13	5.1	No	No	0	8	1
239	B:B:E12	B:B:N16	13.15	No	No	0	4	1
240	B:B:L14	B:B:Q13	6.65	No	No	0	8	1
241	B:B:L14	G:G:L19	5.54	No	No	0	8	9
242	B:B:K15	G:G:L19	5.64	No	No	0	6	9
243	B:B:N16	B:B:R19	12.05	No	No	0	1	4
244	B:B:Q17	G:G:A23	4.55	No	No	0	4	8
245	B:B:I18	B:B:R22	5.01	No	No	0	7	6
246	B:B:D20	B:B:R19	4.76	No	No	0	2	4
247	B:B:D258	B:B:R22	9.53	Yes	No	0	7	6
248	B:B:C25	G:G:V30	3.42	No	No	0	3	8
249	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
250	B:B:A28	B:B:D27	4.63	No	No	0	4	8
251	B:B:A28	G:G:S31	3.42	No	No	0	4	9
252	B:B:S31	B:B:T29	3.2	No	No	0	1	3
253	B:B:Q32	B:B:T29	11.34	No	No	0	1	3
254	B:B:L30	B:B:M262	5.65	No	Yes	0	5	4
255	B:B:L30	G:G:A34	4.73	No	No	0	5	6
256	B:B:M262	B:B:S31	3.07	Yes	No	0	4	1
257	B:B:I37	B:B:T34	4.56	No	No	0	2	5
258	B:B:L300	B:B:T34	4.42	No	No	0	6	5
259	B:B:T34	G:G:M38	4.52	No	No	0	5	4
260	B:B:N35	B:B:N36	6.81	No	No	0	1	1
261	B:B:I37	B:B:R283	6.26	No	Yes	0	2	9
262	B:B:K301	B:B:P39	3.35	No	No	0	5	1
263	B:B:R283	B:B:V40	7.85	Yes	Yes	15	9	3
264	B:B:D298	B:B:V40	8.76	No	Yes	15	9	3
265	B:B:Q44	B:B:R42	7.01	No	No	0	4	2
266	B:B:Q44	B:B:R46	10.51	No	No	0	4	5
267	B:B:M45	B:B:V296	3.04	Yes	Yes	0	4	5
268	B:B:L308	B:B:M45	7.07	No	Yes	0	7	4
269	B:B:M45	G:G:L50	4.24	Yes	No	0	4	9
270	B:B:R46	B:B:R48	6.4	No	No	0	5	7
271	B:B:T47	B:B:T50	3.14	No	No	0	3	3
272	B:B:T47	B:B:W339	7.28	No	Yes	0	3	9
273	B:B:N340	B:B:R48	7.23	No	No	0	9	7
274	B:B:R49	B:B:T87	5.17	No	No	0	7	5
275	B:B:I338	B:B:R49	5.01	Yes	No	4	5	7
276	B:B:R49	G:G:F61	3.21	No	Yes	4	7	8
277	B:B:R52	B:B:T50	3.88	No	No	0	7	3
278	B:B:K337	B:B:T50	9.01	No	No	0	6	3
279	B:B:L51	B:B:W82	15.94	Yes	Yes	4	9	9
280	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
281	B:B:L336	B:B:L51	6.92	Yes	Yes	4	7	9
282	B:B:I338	B:B:L51	4.28	Yes	Yes	4	5	9
283	B:B:F335	B:B:R52	3.21	No	No	0	4	7
284	B:B:H54	B:B:I58	7.95	Yes	No	4	9	9
285	B:B:H54	B:B:S72	8.37	Yes	No	4	9	9
286	B:B:H54	B:B:S74	12.55	Yes	No	4	9	9
287	B:B:H54	B:B:I80	13.26	Yes	No	4	9	8
288	B:B:H54	B:B:W82	3.17	Yes	Yes	4	9	9
289	B:B:D76	B:B:L55	10.86	No	No	0	9	6
290	B:B:K57	B:B:Y59	7.17	No	Yes	1	9	8
291	B:B:K57	B:B:W332	23.21	No	Yes	1	9	9
292	B:B:I58	B:B:S74	3.1	No	No	4	9	9
293	B:B:I58	B:B:L336	4.28	No	Yes	4	9	7
294	B:B:Q75	B:B:Y59	10.15	No	Yes	1	9	8
295	B:B:S316	B:B:Y59	3.82	No	Yes	1	9	8
296	B:B:W332	B:B:Y59	11.58	Yes	Yes	1	9	8
297	B:B:M61	B:B:W63	4.65	No	Yes	4	6	7
298	B:B:L70	B:B:M61	4.24	No	No	4	5	6
299	B:B:C317	B:B:M61	4.86	No	No	0	7	6
300	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
301	B:B:H62	B:B:R150	14.67	No	No	0	6	6
302	B:B:L70	B:B:W63	10.25	No	Yes	4	5	7
303	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
304	B:B:T321	B:B:W63	12.13	No	Yes	4	7	7
305	B:B:A328	B:B:W63	5.19	No	Yes	0	5	7
306	B:B:I338	B:B:W63	3.52	Yes	Yes	4	5	7
307	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
308	B:B:D66	B:B:R68	3.57	No	No	0	8	5
309	B:B:D66	B:B:L69	5.43	No	No	0	8	5
310	B:B:S67	B:B:T321	9.59	No	No	4	5	7
311	B:B:D323	B:B:S67	10.31	No	No	4	7	5
312	B:B:D83	B:B:R68	16.68	No	No	0	8	5
313	B:B:R68	B:B:Y85	14.4	No	No	0	5	4
314	B:B:I81	B:B:L69	4.28	Yes	No	0	7	5
315	B:B:L69	B:B:Y105	3.52	No	Yes	0	5	6
316	B:B:L70	B:B:W82	4.56	No	Yes	4	5	9
317	B:B:L79	B:B:V71	4.47	Yes	Yes	12	7	8
318	B:B:I81	B:B:V71	4.61	Yes	Yes	0	7	8
319	B:B:V71	B:B:Y105	3.79	Yes	Yes	0	8	6
320	B:B:V112	B:B:V71	3.21	No	Yes	12	8	8
321	B:B:S72	B:B:W82	7.41	No	Yes	4	9	9
322	B:B:L336	B:B:S72	7.51	Yes	No	4	7	9
323	B:B:A73	B:B:V100	5.09	No	No	0	9	9
324	B:B:A73	B:B:C103	3.61	No	No	0	9	8
325	B:B:Q75	B:B:W99	6.57	No	Yes	1	9	9
326	B:B:D76	B:B:K78	4.15	No	No	0	9	8
327	B:B:K78	B:B:P94	3.35	No	No	0	8	5
328	B:B:I93	B:B:L79	8.56	Yes	Yes	0	7	7
329	B:B:L79	B:B:L95	5.54	Yes	Yes	12	7	8
330	B:B:L79	B:B:V112	5.96	Yes	No	12	7	8
331	B:B:C114	B:B:L79	6.35	No	Yes	12	8	7
332	B:B:I80	B:B:W82	14.09	No	Yes	4	8	9
333	B:B:I80	B:B:K89	4.36	No	Yes	4	8	9
334	B:B:H91	B:B:I81	3.98	Yes	Yes	0	5	7
335	B:B:I81	B:B:L126	4.28	Yes	No	0	7	5
336	B:B:K89	B:B:W82	13.92	Yes	Yes	4	9	9
337	B:B:L336	B:B:W82	5.69	Yes	Yes	4	7	9
338	B:B:D83	B:B:T86	5.78	No	No	0	8	6
339	B:B:S84	G:G:F61	5.28	No	Yes	0	5	8
340	B:B:Y85	G:G:P60	11.13	No	No	0	4	9
341	B:B:Y85	G:G:F61	8.25	No	Yes	0	4	8
342	B:B:N88	B:B:T86	10.24	No	No	0	7	6
343	B:B:H91	B:B:V90	5.54	Yes	No	0	5	5
344	B:B:H91	B:B:V133	4.15	Yes	No	0	5	4
345	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
346	B:B:I93	B:B:Y124	8.46	Yes	Yes	0	7	6
347	B:B:I93	B:B:V133	3.07	Yes	No	0	7	4
348	B:B:L95	B:B:V100	4.47	Yes	No	12	8	9
349	B:B:C114	B:B:L95	4.76	No	Yes	12	8	8
350	B:B:L95	B:B:Y124	5.86	Yes	Yes	0	8	6
351	B:B:S97	B:B:W99	3.71	No	Yes	0	8	9
352	B:B:D118	B:B:S97	8.83	No	No	0	9	8
353	B:B:S98	B:B:W99	8.65	No	Yes	0	8	9
354	B:B:L117	B:B:W99	5.69	Yes	Yes	1	9	9
355	B:B:C114	B:B:V100	3.42	No	No	12	8	9
356	B:B:G116	B:B:M101	3.49	No	No	0	9	9
357	B:B:M101	B:B:Y145	4.79	No	Yes	0	9	8
358	B:B:C148	B:B:T102	3.38	Yes	No	0	6	8
359	B:B:C149	B:B:T102	6.76	No	No	0	8	8
360	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
361	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
362	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
363	B:B:N110	B:B:S108	7.45	Yes	No	13	4	6
364	B:B:D154	B:B:S108	8.83	No	No	13	6	6
365	B:B:K127	B:B:N110	9.79	No	Yes	0	4	4
366	B:B:D154	B:B:N110	4.04	No	Yes	13	6	4
367	B:B:I123	B:B:Y111	4.84	No	Yes	13	6	4
368	B:B:N125	B:B:Y111	12.79	No	Yes	0	4	4
369	B:B:S136	B:B:Y111	6.36	No	Yes	0	4	4
370	B:B:F151	B:B:Y111	3.09	Yes	Yes	13	9	4
371	B:B:L126	B:B:V112	4.47	No	No	0	5	8
372	B:B:D118	B:B:G115	3.35	No	No	0	9	9
373	B:B:G115	B:B:L146	3.42	No	Yes	0	9	7
374	B:B:D118	B:B:I120	7	No	No	0	9	6
375	B:B:G144	B:B:N119	3.39	No	No	0	8	9
376	B:B:I120	B:B:S122	3.1	No	No	0	6	8
377	B:B:E138	B:B:I120	4.1	No	No	0	6	6
378	B:B:C121	B:B:L139	6.35	No	No	0	8	9
379	B:B:C121	B:B:L146	3.17	No	Yes	1	8	7
380	B:B:C121	B:B:T159	3.38	No	Yes	1	8	9
381	B:B:S122	B:B:Y124	5.09	No	Yes	0	8	6
382	B:B:I123	B:B:L139	4.28	No	No	0	6	9
383	B:B:F151	B:B:I123	3.77	Yes	No	13	9	6
384	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
385	B:B:N125	B:B:T128	4.39	No	No	0	4	3
386	B:B:E130	B:B:N132	6.57	Yes	No	20	3	3
387	B:B:E130	B:B:R134	16.28	Yes	No	20	3	3
388	B:B:N132	B:B:R134	13.26	No	No	20	3	3
389	B:B:L139	B:B:W169	11.39	No	Yes	0	9	8
390	B:B:H142	B:B:L146	3.86	Yes	Yes	1	9	7
391	B:B:H142	B:B:T159	6.85	Yes	Yes	1	9	9
392	B:B:H142	B:B:S161	16.74	Yes	No	1	9	9
393	B:B:D163	B:B:H142	8.82	Yes	Yes	1	9	9
394	B:B:H142	B:B:W169	8.46	Yes	Yes	1	9	8
395	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
396	B:B:D163	B:B:G144	5.03	Yes	No	0	9	8
397	B:B:G162	B:B:Y145	10.14	No	Yes	1	9	8
398	B:B:D186	B:B:Y145	4.6	Yes	Yes	1	9	8
399	B:B:M188	B:B:Y145	3.59	Yes	Yes	1	8	8
400	B:B:L146	B:B:T159	7.37	Yes	Yes	1	7	9
401	B:B:S147	B:B:S160	4.89	No	No	0	9	6
402	B:B:C148	B:B:R150	4.18	Yes	No	0	6	6
403	B:B:C148	B:B:S160	3.44	Yes	No	0	6	6
404	B:B:C148	B:B:L190	3.17	Yes	No	0	6	5
405	B:B:L192	B:B:R150	3.64	No	No	0	5	6
406	B:B:F151	B:B:I157	10.05	Yes	No	0	9	7
407	B:B:L152	B:B:Q156	3.99	No	Yes	0	3	5
408	B:B:D153	B:B:Q156	6.53	No	Yes	0	5	5
409	B:B:D170	B:B:N155	10.77	Yes	No	21	9	3
410	B:B:I171	B:B:N155	4.25	No	No	0	6	3
411	B:B:E172	B:B:N155	19.72	No	No	21	6	3
412	B:B:L168	B:B:Q156	7.99	No	Yes	0	6	5
413	B:B:D170	B:B:Q156	5.22	Yes	Yes	0	9	5
414	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
415	B:B:L190	B:B:V158	4.47	No	No	5	5	5
416	B:B:F199	B:B:V158	5.24	Yes	No	5	9	5
417	B:B:T159	B:B:W169	10.92	Yes	Yes	1	9	8
418	B:B:S160	B:B:V187	6.46	No	Yes	0	6	9
419	B:B:G162	B:B:S161	3.71	No	No	1	9	9
420	B:B:D163	B:B:S161	10.31	Yes	No	1	9	9
421	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
422	B:B:D163	B:B:T165	5.78	Yes	No	0	9	7
423	B:B:T165	B:B:T181	3.14	No	No	0	7	2
424	B:B:C166	B:B:F180	4.19	Yes	Yes	5	8	7
425	B:B:C166	B:B:V187	5.12	Yes	Yes	5	8	9
426	B:B:C166	B:B:F199	4.19	Yes	Yes	5	8	9
427	B:B:C166	B:B:S201	3.44	Yes	Yes	5	8	9
428	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
429	B:B:A167	B:B:Q176	4.55	No	Yes	1	4	4
430	B:B:L168	B:B:T178	4.42	No	No	0	6	4
431	B:B:Q176	B:B:W169	14.24	Yes	Yes	1	4	8
432	B:B:D170	B:B:E172	5.2	Yes	No	21	9	6
433	B:B:D170	B:B:T173	5.78	Yes	No	0	9	5
434	B:B:Q175	B:B:T173	7.09	No	No	0	4	5
435	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
436	B:B:T177	B:B:T178	3.14	No	No	0	4	4
437	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
438	B:B:F180	B:B:F199	12.86	Yes	Yes	5	7	9
439	B:B:F180	B:B:W211	14.03	Yes	Yes	5	7	8
440	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
441	B:B:H183	B:B:V187	5.54	Yes	Yes	5	9	9
442	B:B:H183	B:B:S201	5.58	Yes	Yes	5	9	9
443	B:B:A203	B:B:H183	8.78	No	Yes	5	8	9
444	B:B:D205	B:B:H183	8.82	Yes	Yes	5	9	9
445	B:B:H183	B:B:K209	20.96	Yes	Yes	5	9	6
446	B:B:H183	B:B:W211	3.17	Yes	Yes	5	9	8
447	B:B:D205	B:B:T184	5.78	Yes	No	0	9	3
448	B:B:D205	B:B:G185	5.03	Yes	No	0	9	5
449	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
450	B:B:S201	B:B:V187	3.23	Yes	Yes	5	9	9
451	B:B:A203	B:B:V187	3.39	No	Yes	5	8	9
452	B:B:C204	B:B:M188	3.24	Yes	Yes	1	7	8
453	B:B:M188	B:B:N230	4.21	Yes	No	1	8	9
454	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
455	B:B:F199	B:B:L190	3.65	Yes	No	5	9	5
456	B:B:I232	B:B:S191	3.1	Yes	No	0	8	8
457	B:B:F234	B:B:S191	7.93	No	No	0	5	8
458	B:B:F199	B:B:L192	3.65	Yes	No	0	9	5
459	B:B:A193	B:B:D195	3.09	Yes	No	0	4	5
460	B:B:A193	B:B:L198	3.15	Yes	No	0	4	3
461	B:B:A193	B:B:F234	4.16	Yes	No	0	4	5
462	B:B:G238	B:B:P194	4.06	No	No	0	7	4
463	B:B:D195	B:B:R197	4.76	No	No	0	5	5
464	B:B:R197	B:B:R214	5.33	No	No	0	5	9
465	B:B:L198	B:B:L210	6.92	No	Yes	0	3	5
466	B:B:F199	B:B:W211	12.03	Yes	Yes	5	9	8
467	B:B:L210	B:B:V200	4.47	Yes	No	0	5	6
468	B:B:F234	B:B:V200	7.87	No	No	0	5	6
469	B:B:F241	B:B:V200	10.49	Yes	No	0	6	6
470	B:B:S201	B:B:W211	7.41	Yes	Yes	5	9	8
471	B:B:G202	B:B:I229	3.53	No	No	0	6	7
472	B:B:G202	B:B:I232	3.53	No	Yes	0	6	8
473	B:B:A203	B:B:D205	4.63	No	Yes	5	8	9
474	B:B:C204	B:B:D228	9.34	Yes	Yes	1	7	9
475	B:B:D205	B:B:S207	7.36	Yes	Yes	5	9	5
476	B:B:D205	B:B:K209	4.15	Yes	Yes	5	9	6
477	B:B:K209	B:B:S207	6.12	Yes	Yes	5	6	5
478	B:B:S207	B:B:T221	3.2	Yes	No	5	5	7
479	B:B:K209	B:B:W211	6.96	Yes	Yes	5	6	8
480	B:B:C218	B:B:K209	4.85	No	Yes	5	5	6
481	B:B:K209	B:B:T221	12.01	Yes	No	5	6	7
482	B:B:L210	B:B:Q220	3.99	Yes	No	0	5	7
483	B:B:L210	B:B:L255	8.3	Yes	No	0	5	6
484	B:B:C218	B:B:W211	5.22	No	Yes	5	5	8
485	B:B:D212	B:B:E215	5.2	No	No	0	9	3
486	B:B:D212	B:B:R219	5.96	No	No	0	9	5
487	B:B:E215	B:B:M217	5.41	No	No	0	3	3
488	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
489	B:B:F222	B:B:Q220	7.03	Yes	No	7	8	7
490	B:B:D258	B:B:Q220	13.05	Yes	No	7	7	7
491	B:B:T221	G:G:E22	8.47	No	No	0	7	9
492	B:B:F222	B:B:F241	10.72	Yes	Yes	7	8	6
493	B:B:F222	B:B:F253	11.79	Yes	Yes	7	8	6
494	B:B:D258	B:B:F222	4.78	Yes	Yes	7	7	8
495	B:B:H225	B:B:I229	7.95	Yes	No	0	9	7
496	B:B:H225	B:B:T243	8.21	Yes	No	7	9	8
497	B:B:H225	B:B:S245	15.34	Yes	No	7	9	9
498	B:B:H225	B:B:T249	4.11	Yes	Yes	7	9	6
499	B:B:H225	B:B:R251	21.44	Yes	Yes	7	9	8
500	B:B:F253	B:B:H225	3.39	Yes	Yes	7	6	9
501	B:B:D247	B:B:E226	12.99	No	No	0	9	3
502	B:B:E226	B:B:R251	3.49	No	Yes	0	3	8
503	B:B:D246	B:B:S227	4.42	Yes	No	0	9	6
504	B:B:D247	B:B:S227	8.83	No	No	0	9	6
505	B:B:D228	B:B:D246	5.32	Yes	Yes	1	9	9
506	B:B:D246	B:B:N230	9.42	Yes	No	1	9	9
507	B:B:A231	B:B:V276	5.09	No	No	0	5	6
508	B:B:I232	B:B:T243	3.04	Yes	No	0	8	8
509	B:B:F235	B:B:P236	10.11	Yes	Yes	6	6	7
510	B:B:F235	B:B:F278	9.65	Yes	Yes	6	6	7
511	B:B:F235	B:B:G282	6.02	Yes	No	6	6	9
512	B:B:F235	G:G:L37	7.31	Yes	No	0	6	7
513	B:B:F235	G:G:Y40	5.16	Yes	Yes	6	6	6
514	B:B:F278	B:B:P236	4.33	Yes	Yes	6	7	7
515	B:B:G282	B:B:P236	4.06	No	Yes	6	9	7
516	B:B:P236	G:G:Y40	5.56	Yes	Yes	6	7	6
517	B:B:N237	B:B:N239	8.17	No	No	0	5	2
518	B:B:N237	G:G:Y40	10.47	No	Yes	0	5	6
519	B:B:N239	B:B:R256	15.67	No	No	0	2	9
520	B:B:A240	G:G:L37	3.15	No	No	0	6	7
521	B:B:F241	B:B:F253	9.65	Yes	Yes	7	6	6
522	B:B:F241	B:B:L255	3.65	Yes	No	0	6	6
523	B:B:F253	B:B:T243	9.08	Yes	No	7	6	8
524	B:B:G244	B:B:I273	5.29	No	Yes	0	5	6
525	B:B:D247	B:B:S245	4.42	No	No	0	9	9
526	B:B:S245	B:B:T249	4.8	No	Yes	7	9	6
527	B:B:A248	B:B:I269	4.87	No	No	0	5	4
528	B:B:R251	B:B:T249	9.06	Yes	Yes	7	8	6
529	B:B:S265	B:B:T249	3.2	No	Yes	0	2	6
530	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
531	B:B:C250	B:B:I273	4.91	No	Yes	0	8	6
532	B:B:F253	B:B:R251	4.28	Yes	Yes	7	6	8
533	B:B:E260	B:B:R251	22.1	No	Yes	7	6	8
534	B:B:R251	B:B:T263	7.76	Yes	No	7	8	1
535	B:B:L252	B:B:M262	4.24	No	Yes	6	7	4
536	B:B:L252	B:B:Y264	5.86	No	Yes	6	7	5
537	B:B:E260	B:B:F253	7	No	Yes	7	6	6
538	B:B:A257	B:B:D254	6.18	No	No	0	7	9
539	B:B:D254	B:B:L261	4.07	No	No	0	9	5
540	B:B:D254	G:G:A33	4.63	No	No	0	9	7
541	B:B:R256	G:G:I28	8.77	No	No	0	9	4
542	B:B:R256	G:G:D36	8.34	No	No	0	9	5
543	B:B:D258	G:G:R27	8.34	Yes	No	0	7	8
544	B:B:Q259	G:G:V30	4.3	No	No	0	6	8
545	B:B:E260	B:B:T263	8.47	No	No	7	6	1
546	B:B:M262	B:B:Y264	10.78	Yes	Yes	6	4	5
547	B:B:L285	B:B:Y264	4.69	Yes	Yes	6	6	5
548	B:B:W297	B:B:Y264	11.58	Yes	Yes	6	8	5
549	B:B:H266	B:B:N268	8.93	No	No	0	4	4
550	B:B:H266	B:B:R304	5.64	No	No	0	4	5
551	B:B:I269	B:B:Y289	6.04	No	Yes	0	4	7
552	B:B:I269	B:B:R304	3.76	No	No	0	4	5
553	B:B:C271	B:B:Y289	5.38	No	Yes	6	5	7
554	B:B:C271	B:B:D290	3.11	No	Yes	0	5	6
555	B:B:C271	B:B:D291	7.78	No	No	6	5	8
556	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
557	B:B:A287	B:B:I273	3.25	No	Yes	0	6	6
558	B:B:I273	B:B:Y289	9.67	Yes	Yes	0	6	7
559	B:B:D290	B:B:T274	5.78	Yes	No	0	6	8
560	B:B:S316	B:B:T274	3.2	No	No	0	9	8
561	B:B:L318	B:B:S275	7.51	No	No	0	6	8
562	B:B:G319	B:B:S277	3.71	No	No	0	5	5
563	B:B:S277	B:B:V320	3.23	No	No	0	5	7
564	B:B:F278	B:B:L285	7.31	Yes	Yes	6	7	6
565	B:B:L284	B:B:S279	6.01	No	No	0	5	9
566	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
567	B:B:S281	G:G:D48	8.83	No	Yes	0	9	9
568	B:B:D298	B:B:R283	15.48	No	Yes	15	9	9
569	B:B:L300	B:B:R283	7.29	No	Yes	15	6	9
570	B:B:R283	G:G:C41	5.57	Yes	No	15	9	7
571	B:B:L284	B:B:V296	4.47	No	Yes	0	5	5
572	B:B:L285	B:B:W297	4.56	Yes	Yes	6	6	8
573	B:B:L286	B:B:V327	4.47	No	No	0	7	6
574	B:B:D291	B:B:Y289	8.05	No	Yes	6	8	7
575	B:B:N295	B:B:Y289	10.47	Yes	Yes	6	6	7
576	B:B:W297	B:B:Y289	6.75	Yes	Yes	6	8	7
577	B:B:D290	B:B:R314	25.01	Yes	No	0	6	8
578	B:B:D291	B:B:N293	6.73	No	No	0	8	5
579	B:B:F292	B:B:N313	6.04	No	No	0	4	7
580	B:B:A309	B:B:N293	4.69	No	No	0	3	5
581	B:B:C294	B:B:L308	6.35	Yes	No	0	5	7
582	B:B:C294	B:B:V315	5.12	Yes	No	14	5	7
583	B:B:C294	B:B:T329	5.07	Yes	Yes	14	5	8
584	B:B:N295	B:B:W297	4.52	Yes	Yes	6	6	8
585	B:B:N295	B:B:R304	16.87	Yes	No	0	6	5
586	B:B:D298	B:B:K301	8.3	No	No	0	9	5
587	B:B:L300	G:G:C41	6.35	No	No	15	6	7
588	B:B:D303	B:B:K301	4.15	No	No	0	2	5
589	B:B:L308	B:B:W339	10.25	No	Yes	0	7	9
590	B:B:H311	B:B:V315	4.15	Yes	No	14	9	7
591	B:B:H311	B:B:T329	6.85	Yes	Yes	14	9	8
592	B:B:H311	B:B:S331	16.74	Yes	No	14	9	9
593	B:B:D333	B:B:H311	7.56	Yes	Yes	14	9	9
594	B:B:H311	B:B:K337	10.48	Yes	No	0	9	6
595	B:B:D312	B:B:D333	7.98	No	Yes	0	5	9
596	B:B:D312	R:R:K616	5.53	No	No	0	5	7
597	B:B:N313	B:B:W332	6.78	No	Yes	0	7	9
598	B:B:R314	B:B:W332	19.99	No	Yes	0	8	9
599	B:B:T329	B:B:V315	4.76	Yes	No	14	8	7
600	B:B:S316	B:B:W332	4.94	No	Yes	1	9	9
601	B:B:G319	B:B:L318	3.42	No	No	0	5	6
602	B:B:V320	B:B:V327	3.21	No	No	0	7	6
603	B:B:D323	B:B:T321	8.67	No	No	4	7	7
604	B:B:D323	B:B:M325	5.54	No	Yes	0	7	5
605	B:B:M325	G:G:P49	6.71	Yes	No	0	5	7
606	B:B:M325	G:G:P60	6.71	Yes	No	0	5	9
607	B:B:M325	G:G:F61	3.73	Yes	Yes	0	5	8
608	B:B:A326	G:G:F61	5.55	No	Yes	0	7	8
609	B:B:T329	B:B:W339	4.85	Yes	Yes	0	8	9
610	B:B:D333	B:B:S331	8.83	Yes	No	14	9	9
611	B:B:D333	B:B:F335	10.75	Yes	No	0	9	4
612	B:B:K337	B:B:W339	6.96	No	Yes	0	6	9
613	B:B:I338	G:G:F61	3.77	Yes	Yes	4	5	8
614	B:B:N340	G:G:N59	8.17	No	Yes	0	9	9
615	B:B:N340	G:G:F61	3.62	No	Yes	0	9	8
616	G:G:I9	G:G:R13	8.77	No	No	0	2	6
617	G:G:L15	G:G:Q11	3.99	No	No	0	2	3
618	G:G:E17	G:G:K20	5.4	No	No	0	6	6
619	G:G:I25	G:G:R27	11.27	No	No	0	2	8
620	G:G:A33	G:G:I28	3.25	No	No	0	7	4
621	G:G:H44	G:G:Y40	16.33	No	Yes	0	6	6
622	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
623	G:G:D48	G:G:L51	12.21	Yes	No	0	9	6
624	G:G:P55	G:G:V54	5.3	No	No	22	5	6
625	G:G:E58	G:G:V54	4.28	No	No	22	5	6
626	G:G:N59	G:G:V54	7.39	Yes	No	0	9	6
627	G:G:P55	G:G:S57	3.56	No	No	0	5	6
628	G:G:E58	G:G:P55	9.43	No	No	22	5	5
629	G:G:A56	G:G:R62	5.53	No	No	0	4	7
630	G:G:N59	G:G:P60	6.52	Yes	No	0	9	9
631	G:G:N59	G:G:R62	3.62	Yes	No	0	9	7
632	R:R:S568	R:R:S570	4.89	No	Yes	11	9	9
633	R:R:S568	R:R:V577	3.23	No	Yes	11	9	3
634	R:R:F569	R:R:L572	6.09	Yes	Yes	9	9	9
635	R:R:F569	R:R:T589	6.49	Yes	No	0	9	9
636	R:R:F569	R:R:L593	3.65	Yes	No	0	9	8
637	R:R:F569	R:R:F641	5.36	Yes	No	9	9	9
638	R:R:S570	R:R:S574	4.89	Yes	Yes	11	9	9
639	R:R:S570	R:R:V577	4.85	Yes	Yes	11	9	3
640	R:R:H820	R:R:S570	5.58	Yes	Yes	11	8	9
641	R:R:I571	R:R:V732	6.14	No	No	0	7	4
642	R:R:I571	R:R:W734	3.52	No	Yes	0	7	8
643	R:R:F641	R:R:L572	3.65	No	Yes	9	9	9
644	R:R:L572	R:R:Y668	7.03	Yes	Yes	9	9	8
645	R:R:F747	R:R:L572	3.65	Yes	Yes	9	8	9
646	R:R:M573	R:R:V748	7.61	Yes	No	0	9	7
647	R:R:A751	R:R:M573	3.22	No	Yes	0	9	9
648	R:R:G807	R:R:M573	5.24	No	Yes	0	9	9
649	R:R:F823	R:R:M573	7.46	No	Yes	0	9	9
650	R:R:P575	R:R:S574	3.56	Yes	Yes	11	6	9
651	R:R:S574	R:R:V577	3.23	Yes	Yes	11	9	3
652	R:R:S574	R:R:T810	3.2	Yes	No	11	9	7
653	R:R:S574	R:R:S814	3.26	Yes	No	11	9	5
654	R:R:H820	R:R:S574	4.18	Yes	Yes	11	8	9
655	R:R:P575	R:R:W737	20.27	Yes	No	0	6	6
656	R:R:I811	R:R:P575	3.39	No	Yes	0	5	6
657	R:R:P575	R:R:S814	3.56	Yes	No	11	6	5
658	R:R:P578	R:R:V577	3.53	Yes	Yes	0	4	3
659	R:R:I581	R:R:P578	6.77	Yes	Yes	0	4	4
660	R:R:H820	R:R:P578	4.58	Yes	Yes	0	8	4
661	R:R:I581	R:R:V584	3.07	Yes	No	0	4	3
662	R:R:I581	R:R:V585	6.14	Yes	No	0	4	8
663	R:R:F582	R:R:P583	4.33	No	No	0	1	1
664	R:R:F582	R:R:K586	6.2	No	No	0	1	3
665	R:R:I588	R:R:V585	3.07	No	No	0	9	8
666	R:R:K586	R:R:W587	3.48	No	No	0	3	4
667	R:R:F829	R:R:G592	4.52	No	No	0	7	9
668	R:R:D638	R:R:L593	5.43	Yes	No	0	7	8
669	R:R:F829	R:R:I595	5.02	No	No	0	7	7
670	R:R:D638	R:R:S596	4.42	Yes	No	0	7	9
671	R:R:G831	R:R:S596	3.71	No	No	0	9	9
672	R:R:I597	R:R:L635	4.28	No	No	0	7	8
673	R:R:L600	R:R:L634	4.15	No	No	0	9	9
674	R:R:L600	R:R:L635	8.3	No	No	0	9	8
675	R:R:I601	R:R:L635	4.28	No	No	0	5	8
676	R:R:L602	R:R:L835	4.15	No	No	0	6	8
677	R:R:C603	R:R:L835	3.17	No	No	0	7	8
678	R:R:A631	R:R:L604	3.15	No	No	0	8	8
679	R:R:I606	R:R:L849	5.71	No	No	0	8	7
680	R:R:E607	R:R:W611	6.54	No	No	0	9	9
681	R:R:E607	R:R:R624	9.3	No	Yes	0	9	9
682	R:R:F610	R:R:L848	8.53	Yes	No	0	8	7
683	R:R:F610	R:R:K852	3.72	Yes	No	0	8	4
684	R:R:K615	R:R:W611	4.64	Yes	No	0	8	9
685	R:R:K612	R:R:K615	5.75	No	Yes	3	7	8
686	R:R:K612	R:R:K616	10.06	No	No	0	7	7
687	R:R:H621	R:R:K612	6.55	No	No	3	6	7
688	R:R:I614	R:R:K844	4.36	No	No	0	7	8
689	R:R:K615	R:R:S620	3.06	Yes	No	3	8	8
690	R:R:H621	R:R:K615	22.27	No	Yes	3	6	8
691	R:R:K615	R:R:R624	9.9	Yes	Yes	3	8	9
692	R:R:S617	R:R:T619	4.8	No	No	3	8	8
693	R:R:S617	R:R:S620	3.26	No	No	3	8	8
694	R:R:Q618	R:R:R685	5.84	No	Yes	0	7	8
695	R:R:H692	R:R:Q618	6.18	No	No	0	6	7
696	R:R:Q618	R:R:Q695	7.68	No	No	0	7	6
697	R:R:R685	R:R:T619	12.94	Yes	No	3	8	8
698	R:R:R624	R:R:S620	3.95	Yes	No	3	9	8
699	R:R:L681	R:R:T622	7.37	No	No	0	7	7
700	R:R:T622	W:W:?1	4.85	No	Yes	0	7	0
701	R:R:R623	R:R:R624	7.46	No	Yes	0	9	9
702	R:R:M627	R:R:R623	7.44	No	No	0	7	9
703	R:R:I625	R:R:M699	4.37	No	No	0	7	7
704	R:R:I625	W:W:?1	4.7	No	Yes	0	7	0
705	R:R:C626	R:R:L678	3.17	No	No	0	7	8
706	R:R:C626	W:W:?1	3.92	No	Yes	0	7	0
707	R:R:L799	R:R:M627	8.48	No	No	0	6	7
708	R:R:N629	R:R:W674	25.99	No	Yes	3	9	9
709	R:R:F703	R:R:N629	8.46	Yes	No	3	8	9
710	R:R:N629	R:R:Y707	4.65	No	Yes	3	9	9
711	R:R:S633	R:R:S670	4.89	No	No	0	8	8
712	R:R:D638	R:R:L634	8.14	Yes	No	0	7	9
713	R:R:L634	R:R:L671	4.15	No	No	0	9	7
714	R:R:F667	R:R:I636	8.79	No	No	0	8	7
715	R:R:A637	R:R:F667	4.16	No	No	0	9	8
716	R:R:A637	R:R:Y668	4	No	Yes	0	9	8
717	R:R:D638	R:R:Y668	4.6	Yes	Yes	0	7	8
718	R:R:F663	R:R:W640	16.04	No	No	0	8	6
719	R:R:V647	R:R:V656	9.62	No	No	0	5	5
720	R:R:C657	R:R:T649	5.07	No	Yes	16	9	3
721	R:R:K728	R:R:T649	4.5	Yes	Yes	16	5	3
722	R:R:C733	R:R:T649	3.38	No	Yes	16	9	3
723	R:R:N652	R:R:V651	5.91	No	No	0	4	1
724	R:R:N652	R:R:V656	4.43	No	No	0	4	5
725	R:R:S654	R:R:T658	6.4	No	No	0	4	6
726	R:R:C657	R:R:K728	8.08	No	Yes	16	9	5
727	R:R:C657	R:R:C733	7.28	No	No	16	9	9
728	R:R:V661	R:R:Y727	6.31	No	Yes	0	8	9
729	R:R:K728	R:R:V661	3.04	Yes	No	0	5	8
730	R:R:F662	R:R:F663	5.36	No	No	0	8	8
731	R:R:F662	R:R:S714	3.96	No	No	0	8	9
732	R:R:T664	R:R:Y668	3.75	No	Yes	0	7	8
733	R:R:T664	R:R:W734	4.85	No	Yes	0	7	8
734	R:R:H665	R:R:L669	9	Yes	Yes	0	9	9
735	R:R:H665	R:R:S714	4.18	Yes	No	0	9	9
736	R:R:H665	R:R:T717	5.48	Yes	No	0	9	9
737	R:R:H665	R:R:L735	3.86	Yes	Yes	0	9	9
738	R:R:F747	R:R:H665	6.79	Yes	Yes	0	8	9
739	R:R:F666	R:R:F667	5.36	No	No	0	7	8
740	R:R:F666	R:R:L711	4.87	No	No	0	7	7
741	R:R:F666	R:R:S714	9.25	No	No	0	7	9
742	R:R:F747	R:R:Y668	4.13	Yes	Yes	9	8	8
743	R:R:L669	R:R:P710	3.28	Yes	No	0	9	9
744	R:R:L669	R:R:P750	3.28	Yes	No	0	9	9
745	R:R:S670	R:R:Y707	3.82	No	Yes	0	8	9
746	R:R:P710	R:R:S670	3.56	No	No	0	9	8
747	R:R:L671	R:R:M675	4.24	No	Yes	0	7	9
748	R:R:F672	R:R:M675	3.73	Yes	Yes	0	9	9
749	R:R:F672	R:R:F747	7.5	Yes	Yes	0	9	8
750	R:R:A751	R:R:F672	5.55	No	Yes	0	9	9
751	R:R:F672	R:R:W804	16.04	Yes	Yes	0	9	9
752	R:R:F673	R:R:L705	6.09	No	No	0	8	6
753	R:R:C709	R:R:F673	4.19	No	No	0	8	8
754	R:R:F673	R:R:P710	11.56	No	No	0	8	9
755	R:R:M677	R:R:W674	4.65	Yes	Yes	3	6	9
756	R:R:F703	R:R:W674	8.02	Yes	Yes	3	8	9
757	R:R:G706	R:R:W674	4.22	No	Yes	0	9	9
758	R:R:W674	R:R:Y707	7.72	Yes	Yes	3	9	9
759	R:R:W674	W:W:?1	3.75	Yes	Yes	3	9	0
760	R:R:G801	R:R:M675	3.49	No	Yes	0	9	9
761	R:R:L676	R:R:M677	4.24	Yes	Yes	0	7	6
762	R:R:I680	R:R:L676	4.28	No	Yes	0	8	7
763	R:R:I754	R:R:L676	7.14	No	Yes	0	9	7
764	R:R:G702	R:R:M677	3.49	No	Yes	3	7	6
765	R:R:L705	R:R:M677	5.65	No	Yes	0	6	6
766	R:R:M677	W:W:?1	8.14	Yes	Yes	3	6	0
767	R:R:I680	W:W:?1	5.87	No	Yes	0	8	0
768	R:R:L681	R:R:R685	4.86	No	Yes	0	7	8
769	R:R:A683	R:R:V761	3.39	No	No	0	6	8
770	R:R:R685	R:R:Y684	10.29	Yes	Yes	3	8	8
771	R:R:L688	R:R:Y684	7.03	No	Yes	3	6	8
772	R:R:H691	R:R:Y684	6.53	Yes	Yes	3	7	8
773	R:R:M693	R:R:Y684	7.18	No	Yes	3	5	8
774	R:R:M698	R:R:Y684	3.59	No	Yes	3	8	8
775	R:R:M698	R:R:R685	4.96	No	Yes	3	8	8
776	R:R:I686	R:R:L764	5.71	No	No	0	7	7
777	R:R:I686	R:R:K768	7.27	No	No	0	7	8
778	R:R:I687	R:R:L764	4.28	No	No	0	6	7
779	R:R:I687	W:W:?1	9.39	No	Yes	0	6	0
780	R:R:H691	R:R:L688	6.43	Yes	No	3	7	6
781	R:R:L688	W:W:?1	9.11	No	Yes	3	6	0
782	R:R:F690	R:R:V689	9.18	Yes	No	8	8	9
783	R:R:H691	R:R:M693	9.19	Yes	No	3	7	5
784	R:R:H691	W:W:?1	5.29	Yes	Yes	3	7	0
785	R:R:M693	W:W:?1	3.49	No	Yes	3	5	0
786	R:R:H696	R:R:Q695	7.42	No	No	0	5	6
787	R:R:F703	R:R:M699	6.22	Yes	No	0	8	7
788	R:R:G702	W:W:?1	5.63	No	Yes	3	7	0
789	R:R:F703	R:R:Y707	3.09	Yes	Yes	3	8	9
790	R:R:T717	R:R:Y727	4.99	No	Yes	0	9	9
791	R:R:I718	R:R:Q722	6.86	No	No	9	7	7
792	R:R:I718	R:R:Y727	8.46	No	Yes	9	7	9
793	R:R:T721	R:R:Y727	3.75	Yes	Yes	0	9	9
794	R:R:S741	R:R:T721	3.2	No	Yes	0	8	9
795	R:R:P743	R:R:T721	12.24	No	Yes	0	8	9
796	R:R:P723	R:R:Q722	3.16	No	No	0	8	7
797	R:R:Q722	R:R:Y727	5.64	No	Yes	9	7	9
798	R:R:S724	R:R:T726	4.8	No	Yes	0	3	4
799	R:R:N736	R:R:T726	4.39	No	Yes	0	8	4
800	R:R:S738	R:R:T726	3.2	No	Yes	0	2	4
801	R:R:S741	R:R:T726	3.2	No	Yes	0	8	4
802	R:R:L735	R:R:Y727	5.86	Yes	Yes	9	9	9
803	R:R:C733	R:R:K728	3.23	No	Yes	16	9	5
804	R:R:R729	R:R:V732	6.54	No	No	0	5	4
805	R:R:R729	R:R:W734	5	No	Yes	0	5	8
806	R:R:L735	R:R:W734	9.11	Yes	Yes	9	9	8
807	R:R:L744	R:R:W734	4.56	Yes	Yes	9	8	8
808	R:R:F747	R:R:W734	5.01	Yes	Yes	9	8	8
809	R:R:L735	R:R:P743	3.28	Yes	No	0	9	8
810	R:R:L735	R:R:L744	4.15	Yes	Yes	9	9	8
811	R:R:K742	R:R:W737	6.96	No	No	0	7	6
812	R:R:L744	R:R:W737	6.83	Yes	No	0	8	6
813	R:R:K742	R:R:L745	4.23	No	No	0	7	8
814	R:R:L744	R:R:V748	4.47	Yes	No	0	8	7
815	R:R:I811	R:R:V748	4.61	No	No	0	5	7
816	R:R:P750	R:R:V749	3.53	No	No	0	9	7
817	R:R:I808	R:R:L752	4.28	No	No	0	7	8
818	R:R:I754	R:R:N758	4.25	No	No	0	9	9
819	R:R:L800	R:R:N758	10.98	No	No	0	9	9
820	R:R:F759	R:R:L763	6.09	No	No	0	4	4
821	R:R:L796	R:R:V762	4.47	No	No	0	9	8
822	R:R:L802	R:R:V762	4.47	No	No	0	7	8
823	R:R:L766	R:R:V789	4.47	No	Yes	0	7	8
824	R:R:L766	R:R:L793	5.54	No	No	0	7	7
825	R:R:R771	R:R:T767	3.88	No	No	0	8	4
826	R:R:T785	R:R:W770	3.64	No	No	0	7	6
827	R:R:V789	R:R:W770	3.68	Yes	No	0	8	6
828	R:R:P772	R:R:R771	5.76	No	No	0	7	8
829	R:R:R777	R:R:T773	10.35	Yes	No	0	5	6
830	R:R:R777	R:R:V774	6.54	Yes	No	2	5	5
831	R:R:E776	R:R:G775	3.27	No	No	0	5	6
832	R:R:R777	R:R:R780	8.53	Yes	No	2	5	3
833	R:R:D782	R:R:S779	4.42	No	No	0	7	4
834	R:R:I787	R:R:R788	5.01	No	No	0	4	7
835	R:R:K791	R:R:R788	7.43	No	No	0	8	7
836	R:R:F837	R:R:L794	9.74	No	No	0	8	6
837	R:R:L794	R:R:L841	4.15	No	No	0	6	5
838	R:R:G838	R:R:I795	3.53	No	No	0	8	7
839	R:R:L796	R:R:L800	6.92	No	No	0	9	9
840	R:R:P798	R:R:T797	3.5	No	No	0	9	9
841	R:R:L802	R:R:T797	8.84	No	No	0	7	9
842	R:R:T803	R:R:W804	3.64	No	Yes	24	9	9
843	R:R:N827	R:R:T803	10.24	No	No	24	9	9
844	R:R:N827	R:R:W804	18.08	No	Yes	24	9	9
845	R:R:Q830	R:R:W804	7.67	No	Yes	0	9	9
846	R:R:F806	R:R:I822	3.77	No	No	0	8	5
847	R:R:F806	R:R:F823	4.29	No	No	0	8	9
848	R:R:F806	R:R:L826	3.65	No	No	0	8	6
849	R:R:H820	R:R:T810	6.85	Yes	No	11	8	7
850	R:R:D813	R:R:Q815	6.53	No	No	0	4	3
851	R:R:D813	R:R:N816	10.77	No	No	0	4	5
852	R:R:N816	R:R:W819	14.69	No	No	0	5	6
853	R:R:F823	R:R:N827	10.87	No	No	0	9	9
854	R:R:L825	R:R:L826	5.54	No	No	0	5	6
855	R:R:F829	R:R:F832	3.22	No	No	0	7	5
856	R:R:F832	R:R:F833	6.43	No	No	0	5	7
857	R:R:C836	R:R:F832	6.98	No	No	0	7	5
858	R:R:C836	R:R:F837	5.59	No	No	0	7	8
859	R:R:F850	R:R:L840	6.09	No	No	0	3	7
860	R:R:D842	R:R:K844	6.91	No	No	23	9	8
861	R:R:D842	R:R:L845	4.07	No	No	23	9	8
862	R:R:R846	R:R:S843	6.59	No	No	0	7	5
863	R:R:K844	R:R:L845	7.05	No	No	23	8	8
864	R:R:F850	R:R:R846	5.34	No	No	0	3	7
865	R:R:K852	R:R:N851	4.2	No	No	0	4	4
866	B:B:F253	B:B:G224	3.01	Yes	No	0	6	6
867	A:A:G352	R:R:R623	3	No	No	0	8	9
868	R:R:L835	R:R:S599	3	No	No	0	8	8
869	R:R:K730	R:R:T649	3	No	Yes	0	2	3
870	R:R:K728	R:R:T658	3	Yes	No	0	5	6
871	R:R:K768	R:R:T767	3	No	No	0	8	4
872	R:R:L769	R:R:S792	3	No	No	0	7	8
873	B:B:V40	G:G:L51	2.98	Yes	No	0	3	6
874	B:B:L152	B:B:V213	2.98	No	No	0	3	4
875	B:B:L168	B:B:V213	2.98	No	No	0	6	4
876	B:B:L261	G:G:V30	2.98	No	No	0	5	8
877	B:B:L286	B:B:V296	2.98	No	Yes	0	7	5
878	R:R:L676	R:R:V757	2.98	Yes	No	0	7	7
879	R:R:L711	R:R:V715	2.98	No	No	0	7	6
880	R:R:L769	R:R:V789	2.98	No	Yes	0	7	8
881	B:B:N295	B:B:V307	2.96	Yes	No	0	6	3
882	R:R:L793	R:R:T797	2.95	No	No	0	7	9
883	R:R:I606	R:R:I839	2.94	No	No	0	8	7
884	G:G:A43	G:G:H44	2.93	No	No	0	4	6
885	R:R:A746	R:R:H665	2.93	No	Yes	0	9	9
886	A:A:I19	A:A:M18	2.92	Yes	No	0	9	4
887	A:A:D200	A:A:V185	2.92	No	No	0	9	5
888	B:B:I43	B:B:M45	2.92	No	Yes	0	3	4
889	R:R:I630	R:R:M675	2.92	No	Yes	0	8	9
890	R:R:D648	R:R:V651	2.92	No	No	0	5	1
891	R:R:I786	R:R:K783	2.91	No	No	0	6	6
892	A:A:G292	A:A:Y290	2.9	No	No	0	7	7
893	A:A:D328	A:A:T329	2.89	No	No	0	9	9
894	B:B:D322	B:B:T65	2.89	No	No	0	1	1
895	R:R:F833	R:R:P798	2.89	No	No	0	7	9
896	A:A:I19	A:A:L23	2.85	Yes	No	0	9	6
897	A:A:I221	A:A:L39	2.85	No	No	0	8	9
898	B:B:E10	G:G:V16	2.85	No	No	0	8	7
899	R:R:I614	R:R:L848	2.85	No	No	0	7	7
900	R:R:I636	R:R:L632	2.85	No	No	0	7	5
901	R:R:I713	R:R:L669	2.85	No	Yes	0	9	9
902	R:R:I795	R:R:L841	2.85	No	No	0	7	5
903	R:R:I834	R:R:L799	2.85	No	No	0	9	6
904	A:A:I278	A:A:N294	2.83	Yes	No	0	6	3
905	B:B:L14	G:G:K20	2.82	No	No	0	8	6
906	R:R:G809	R:R:W819	2.81	No	No	0	7	6
907	A:A:M18	A:A:N22	2.8	No	No	0	4	4
908	A:A:D217	A:A:K35	2.77	No	No	0	5	9
909	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
910	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
911	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
912	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
913	R:R:A828	R:R:F569	2.77	No	Yes	0	8	9
914	R:R:L678	R:R:L682	2.77	No	No	0	8	9
915	R:R:D731	R:R:K730	2.77	No	No	0	3	2
916	A:A:E14	A:A:K17	2.7	No	No	0	3	4
917	A:A:E276	A:A:K279	2.7	No	No	0	5	2
918	B:B:K280	G:G:E47	2.7	No	No	0	1	3
919	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
920	A:A:D226	A:A:D229	2.66	No	No	0	8	8
921	A:A:Q304	R:R:L778	2.66	Yes	No	0	5	5
922	B:B:F335	B:B:S334	2.64	No	No	0	4	4
923	R:R:N851	R:R:Q847	2.64	No	No	0	4	6
924	R:R:A660	R:R:W640	2.59	No	No	0	7	6
925	R:R:A683	W:W:?1	2.59	No	Yes	0	6	0
926	B:B:E10	B:B:Q6	2.55	No	No	0	8	1
927	R:R:T589	R:R:Y590	2.5	No	Yes	0	9	5
928	R:R:V628	R:R:W611	2.45	No	No	0	7	9
929	R:R:V643	R:R:W640	2.45	No	No	0	8	6
930	R:R:V701	W:W:?1	2.45	No	Yes	0	6	0
931	B:B:L7	G:G:R13	2.43	No	No	0	8	6
932	B:B:L210	B:B:R219	2.43	Yes	No	0	5	5
933	R:R:I642	R:R:Y590	2.42	No	Yes	0	8	5
934	A:A:N241	A:A:R242	2.41	No	Yes	0	9	9
935	R:R:K586	R:R:Y590	2.39	No	Yes	0	3	5
936	R:R:I786	R:R:W770	2.35	No	No	0	6	6
937	R:R:F610	R:R:Q613	2.34	Yes	No	0	8	5
938	A:A:E28	A:A:R32	2.33	No	No	0	4	4
939	B:B:N110	B:B:Y111	2.33	Yes	Yes	13	4	4
940	A:A:R21	A:A:R24	2.13	No	No	0	4	3
941	A:A:G202	A:A:G203	2.11	No	No	0	9	9
942	B:B:C294	B:B:G288	1.96	Yes	No	0	5	7
943	B:B:C317	B:B:G330	1.96	No	No	0	7	5
944	B:B:A140	B:B:G141	1.95	No	No	0	5	5
945	B:B:A231	B:B:G244	1.95	No	No	0	5	5
946	B:B:A309	B:B:G310	1.95	No	No	0	3	5
947	R:R:A660	R:R:G644	1.95	No	No	0	7	6
948	B:B:A193	B:B:P194	1.87	Yes	No	0	4	4
949	B:B:G77	B:B:S98	1.86	No	No	0	8	8
950	R:R:G831	R:R:S599	1.86	No	No	0	9	8
951	R:R:G740	R:R:S738	1.86	No	No	0	4	2
952	A:A:G202	A:A:V201	1.84	No	Yes	0	9	9
953	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
954	B:B:G306	B:B:V296	1.84	No	Yes	0	4	5
955	B:B:G324	B:B:V320	1.84	No	No	0	9	7
956	R:R:G592	R:R:V591	1.84	No	No	0	9	7
957	R:R:G644	R:R:V647	1.84	No	No	0	6	5
958	R:R:G679	R:R:V761	1.84	No	No	0	9	8
959	R:R:G805	R:R:V755	1.84	No	No	0	6	8
960	R:R:G790	R:R:V789	1.84	No	Yes	0	5	8
961	R:R:G809	R:R:V812	1.84	No	No	0	7	6
962	B:B:G185	B:B:T164	1.82	No	No	0	5	6
963	B:B:G174	B:B:T173	1.82	No	No	0	4	5
964	B:B:G182	B:B:T181	1.82	No	No	0	6	2
965	A:A:A326	A:A:C325	1.81	No	No	0	9	7
966	B:B:A60	B:B:C103	1.81	No	No	0	7	8
967	R:R:A567	R:R:A645	1.79	No	No	0	9	7
968	A:A:P282	A:A:S281	1.78	No	No	0	5	7
969	R:R:G598	R:R:I597	1.76	No	No	0	3	7
970	R:R:G598	R:R:I601	1.76	No	No	0	3	5
971	R:R:G809	R:R:I808	1.76	No	No	0	7	7
972	G:G:P53	G:G:T52	1.75	No	No	0	8	4
973	R:R:P578	R:R:T580	1.75	Yes	No	0	4	3
974	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
975	A:A:G27	B:B:L55	1.71	No	No	0	5	6
976	B:B:A56	B:B:S74	1.71	No	No	0	7	9
977	B:B:C233	B:B:V276	1.71	No	No	0	3	6
978	R:R:G708	R:R:L711	1.71	No	No	0	6	7
979	A:A:A219	A:A:V34	1.7	No	Yes	8	7	5
980	A:A:A219	A:A:V339	1.7	No	Yes	8	7	8
981	B:B:A11	G:G:V16	1.7	No	No	0	5	7
982	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
983	B:B:A305	B:B:V296	1.7	No	Yes	0	4	5
984	R:R:A824	R:R:V585	1.7	No	No	0	8	8
985	A:A:C325	A:A:T327	1.69	No	No	0	7	8
986	A:A:G352	R:R:D842	1.68	No	No	0	8	9
987	B:B:E130	B:B:G131	1.64	Yes	No	0	3	4
988	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
989	R:R:C603	R:R:I839	1.64	No	No	0	7	7
990	R:R:N652	R:R:P653	1.63	No	No	0	4	4
991	A:A:A299	A:A:I278	1.62	No	Yes	0	7	6
992	B:B:I18	G:G:A23	1.62	No	No	0	7	8
993	B:B:I33	G:G:A34	1.62	No	No	0	3	6
994	A:A:A11	A:A:K10	1.61	No	No	0	4	3
995	B:B:D38	B:B:P39	1.61	No	No	0	1	1
996	B:B:S207	B:B:T223	1.6	Yes	No	0	5	2
997	A:A:T262	A:A:V218	1.59	No	No	0	7	9
998	R:R:T650	R:R:V651	1.59	No	No	0	3	1
999	R:R:T721	R:R:V720	1.59	Yes	No	0	9	5
1000	B:B:A11	G:G:L15	1.58	No	No	0	5	2
1001	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
1002	R:R:A631	R:R:L600	1.58	No	No	0	8	9
1003	R:R:A694	R:R:L697	1.58	No	No	0	8	3
1004	R:R:A751	R:R:L752	1.58	No	No	0	9	8
1005	B:B:I33	G:G:S31	1.55	No	No	0	3	9
1006	R:R:I581	R:R:V821	1.54	Yes	No	0	4	7
1007	R:R:I588	R:R:V821	1.54	No	No	0	9	7
1008	R:R:I636	R:R:V639	1.54	No	No	0	7	6
1009	R:R:I642	R:R:V639	1.54	No	No	0	8	6
1010	R:R:I716	R:R:V715	1.54	No	No	0	7	6
1011	R:R:A784	R:R:D781	1.54	No	No	0	6	6
1012	A:A:C305	A:A:Q306	1.53	No	No	0	3	5
1013	G:G:K29	G:G:S31	1.53	No	No	0	4	9
1014	A:A:K17	A:A:V13	1.52	No	No	0	4	3
1015	B:B:L4	G:G:S8	1.5	No	No	0	4	4
1016	R:R:N739	R:R:S738	1.49	No	No	0	4	2
1017	A:A:D226	A:A:S44	1.47	No	No	0	8	9
1018	G:G:L51	G:G:T52	1.47	No	No	0	6	4
1019	R:R:I601	R:R:I605	1.47	No	No	0	5	6
1020	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1021	B:B:D66	B:B:T65	1.45	No	No	0	8	1
1022	B:B:M217	G:G:M21	1.44	No	No	0	3	1
1023	G:G:K29	G:G:K32	1.44	No	No	0	4	5
1024	B:B:I18	G:G:L19	1.43	No	No	0	7	9
1025	R:R:I581	R:R:L817	1.43	Yes	No	0	4	2
1026	B:B:E130	B:B:T128	1.41	Yes	No	0	3	3
1027	A:A:D26	A:A:K29	1.38	No	No	0	5	1
1028	A:A:K314	R:R:D781	1.38	No	No	0	3	6
1029	B:B:D20	B:B:K23	1.38	No	No	0	2	2
1030	B:B:K280	G:G:D48	1.38	No	Yes	0	1	9
1031	G:G:A10	G:G:R13	1.38	No	No	0	2	6
1032	R:R:D782	R:R:K783	1.38	No	No	0	7	6
1033	B:B:E3	G:G:I9	1.37	No	No	0	5	2
1034	B:B:I37	G:G:E42	1.37	No	No	0	2	1
1035	A:A:E276	A:A:K280	1.35	No	No	0	5	1
1036	R:R:A567	R:R:Y590	1.33	No	Yes	0	9	5
1037	B:B:N16	B:B:Q13	1.32	No	No	0	1	1
1038	B:B:R137	B:B:S136	1.32	No	No	0	5	4
1039	R:R:F576	R:R:S814	1.32	No	No	0	3	5
1040	A:A:E25	A:A:N22	1.31	No	No	0	4	4
1041	B:B:D5	B:B:Q6	1.31	No	No	0	1	1
1042	B:B:R96	B:B:V135	1.31	No	No	0	6	4
1043	R:R:A818	R:R:W819	1.3	No	No	0	6	6
1044	A:A:E289	A:A:Q288	1.27	No	No	0	6	5
1045	B:B:E12	B:B:Q9	1.27	No	No	0	4	3
1046	A:A:M18	A:A:R21	1.24	No	No	0	4	4
1047	R:R:V755	R:R:W804	1.23	No	Yes	0	8	9
1048	R:R:F610	R:R:L609	1.22	Yes	No	0	8	4
1049	R:R:F759	R:R:L802	1.22	No	No	0	4	7
1050	A:A:E297	A:A:Y296	1.12	No	Yes	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:I19	3.345	4	0	9
2	A:A:V34	7.005	4	8	5
3	A:A:L36	4.9325	4	8	7
4	A:A:K46	5.8075	4	10	9
5	A:A:I49	5.952	5	10	7
6	A:A:I184	4.835	4	1	9
7	A:A:F191	7.7575	4	8	5
8	A:A:F196	8.02667	6	8	7
9	A:A:F199	8.618	5	1	5
10	A:A:V201	3.4575	4	1	9
11	A:A:Q204	5.452	5	1	9
12	A:A:S206	5.3675	4	1	8
13	A:A:E207	6.502	5	1	9
14	A:A:K210	6.32	8	1	9
15	A:A:W211	6.16	5	1	9
16	A:A:F215	6.61167	6	1	9
17	A:A:Y230	6.915	6	2	8
18	A:A:R242	4.7275	4	0	9
19	A:A:F250	6.36	5	2	9
20	A:A:N255	6.9325	4	0	8
21	A:A:W258	10.2025	4	0	5
22	A:A:I264	5.935	4	2	6
23	A:A:F267	5.04333	6	10	9
24	A:A:N269	5.534	5	10	9
25	A:A:F274	6.6525	4	2	9
26	A:A:I278	4.2175	4	2	6
27	A:A:Y287	5.522	5	2	7
28	A:A:Y296	6.79667	6	2	4
29	A:A:Q304	6.534	5	2	5
30	A:A:F307	6.166	5	2	8
31	A:A:R313	4.7425	4	0	4
32	A:A:K317	6.6875	4	0	7
33	A:A:Y320	6.47429	7	2	7
34	A:A:F323	6.836	5	2	4
35	A:A:T324	6.1325	4	10	9
36	A:A:F334	10.0025	4	0	3
37	A:A:F336	5.9675	4	8	8
38	A:A:V339	3.7275	4	8	8
39	A:A:F354	6.3025	4	0	5
40	B:B:V40	4.626	5	15	3
41	B:B:M45	4.3175	4	0	4
42	B:B:L51	7.89	4	4	9
43	B:B:H54	9.06	5	4	9
44	B:B:Y59	7.395	6	1	8
45	B:B:W63	6.78	6	4	7
46	B:B:V71	4.02	4	12	8
47	B:B:L79	6.176	5	12	7
48	B:B:I81	4.2875	4	0	7
49	B:B:W82	9.25429	7	4	9
50	B:B:K89	6.44167	6	4	9
51	B:B:H91	4.8275	4	0	5
52	B:B:I93	5.87	4	0	7
53	B:B:L95	5.1575	4	12	8
54	B:B:W99	8.85	8	1	9
55	B:B:Y105	4.144	5	0	6
56	B:B:N110	5.9025	4	13	4
57	B:B:Y111	5.882	5	13	4
58	B:B:L117	4.9125	4	1	9
59	B:B:Y124	6.43	4	0	6
60	B:B:E130	6.475	4	20	3
61	B:B:H142	8.946	5	1	9
62	B:B:Y145	5.76375	8	1	8
63	B:B:L146	4.455	4	1	7
64	B:B:C148	3.5425	4	0	6
65	B:B:F151	4.81571	7	13	9
66	B:B:Q156	5.9325	4	0	5
67	B:B:T159	7.13	4	1	9
68	B:B:D163	7.434	5	1	9
69	B:B:C166	4.235	4	5	8
70	B:B:W169	8.95333	6	1	8
71	B:B:D170	6.7425	4	21	9
72	B:B:Q176	6.88	4	1	4
73	B:B:F180	8.418	5	5	7
74	B:B:H183	8.80833	6	5	9
75	B:B:D186	4.472	5	1	9
76	B:B:V187	4.748	5	5	9
77	B:B:M188	5.64	4	1	8
78	B:B:A193	3.0675	4	0	4
79	B:B:F199	6.93667	6	5	9
80	B:B:S201	4.915	4	5	9
81	B:B:C204	5.02	5	1	7
82	B:B:D205	5.96167	6	5	9
83	B:B:S207	4.57	4	5	5
84	B:B:K209	9.175	6	5	6
85	B:B:L210	5.222	5	0	5
86	B:B:W211	8.13667	6	5	8
87	B:B:F222	8.58	4	7	8
88	B:B:H225	8.84286	7	7	9
89	B:B:D228	7.014	5	1	9
90	B:B:I232	3.965	4	0	8
91	B:B:F235	7.65	5	6	6
92	B:B:P236	6.015	4	6	7
93	B:B:F241	7.456	5	7	6
94	B:B:D246	5.8275	4	1	9
95	B:B:T249	5.2925	4	7	6
96	B:B:R251	11.355	6	7	8
97	B:B:F253	6.88571	7	7	6
98	B:B:D258	8.925	4	7	7
99	B:B:M262	5.935	4	6	4
100	B:B:Y264	6.60167	6	6	5
101	B:B:I273	5.78	4	0	6
102	B:B:F278	6.015	4	6	7
103	B:B:R283	8.49	5	15	9
104	B:B:L285	4.535	4	6	6
105	B:B:Y289	7.72667	6	6	7
106	B:B:D290	9.3125	4	0	6
107	B:B:C294	4.625	4	14	5
108	B:B:N295	8.705	4	6	6
109	B:B:V296	2.806	5	0	5
110	B:B:W297	6.8525	4	6	8
111	B:B:H311	9.156	5	14	9
112	B:B:M325	5.6725	4	0	5
113	B:B:T329	5.3825	4	14	8
114	B:B:W332	12.1417	6	1	9
115	B:B:D333	8.78	4	14	9
116	B:B:L336	6.1	4	4	7
117	B:B:I338	4.145	4	4	5
118	B:B:W339	7.335	4	0	9
119	G:G:Y40	9.38	4	6	6
120	G:G:D48	6.894	5	0	9
121	G:G:N59	6.425	4	0	9
122	G:G:F61	4.77286	7	4	8
123	R:R:F569	4.872	5	9	9
124	R:R:S570	5.0525	4	11	9
125	R:R:L572	5.105	4	9	9
126	R:R:M573	5.8825	4	0	9
127	R:R:S574	3.72	6	11	9
128	R:R:P575	7.695	4	11	6
129	R:R:V577	3.71	4	11	3
130	R:R:P578	4.1575	4	0	4
131	R:R:I581	3.79	5	0	4
132	R:R:Y590	2.16	4	0	5
133	R:R:F610	3.9525	4	0	8
134	R:R:K615	9.124	5	3	8
135	R:R:R624	7.6525	4	3	9
136	R:R:D638	5.6475	4	0	7
137	R:R:T649	3.9875	4	16	3
138	R:R:H665	5.37333	6	0	9
139	R:R:Y668	4.702	5	9	8
140	R:R:L669	4.6025	4	0	9
141	R:R:F672	8.205	4	0	9
142	R:R:W674	9.05833	6	3	9
143	R:R:M675	3.595	4	0	9
144	R:R:L676	4.66	4	0	7
145	R:R:M677	5.234	5	3	6
146	R:R:Y684	6.924	5	3	8
147	R:R:R685	7.48667	6	3	8
148	R:R:F690	6.238	5	8	8
149	R:R:H691	6.86	4	3	7
150	R:R:F703	6.4475	4	3	8
151	R:R:Y707	4.82	4	3	9
152	R:R:T721	5.195	4	0	9
153	R:R:T726	3.8975	4	0	4
154	R:R:Y727	5.835	6	9	9
155	R:R:K728	4.37	5	16	5
156	R:R:W734	5.34167	6	9	8
157	R:R:L735	5.252	5	9	9
158	R:R:L744	5.0025	4	9	8
159	R:R:F747	5.416	5	9	8
160	R:R:R777	8.744	5	2	5
161	R:R:V789	3.2425	4	0	8
162	R:R:W804	9.332	5	24	9
163	R:R:H820	5.2975	4	11	8
164	W:W:?1	5.32154	13	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:D66	B:B:R68	100	3.57	No	No	0	8	5
2	B:B:D66	B:B:L69	100	5.43	No	No	0	8	5
3	B:B:I81	B:B:L69	100	4.28	Yes	No	0	7	5
4	B:B:H91	B:B:I81	100	3.98	Yes	Yes	0	5	7
5	B:B:I81	B:B:V71	100	4.61	Yes	Yes	0	7	8
6	B:B:L79	B:B:V71	100	4.47	Yes	Yes	12	7	8
7	B:B:I93	B:B:L79	100	8.56	Yes	Yes	0	7	7
8	B:B:L69	B:B:Y105	100	3.52	No	Yes	0	5	6
9	B:B:V71	B:B:Y105	100	3.79	Yes	Yes	0	8	6
10	B:B:H91	B:B:V133	100	4.15	Yes	No	0	5	4
11	B:B:I93	B:B:V133	100	3.07	Yes	No	0	7	4
12	B:B:I93	B:B:Y124	100	8.46	Yes	Yes	0	7	6
13	B:B:S122	B:B:Y124	100	5.09	No	Yes	0	8	6
14	B:B:I120	B:B:S122	100	3.1	No	No	0	6	8
15	B:B:D118	B:B:I120	100	7	No	No	0	9	6
16	B:B:D118	B:B:S97	100	8.83	No	No	0	9	8
17	B:B:S97	B:B:W99	100	3.71	No	Yes	0	8	9
18	A:A:F199	B:B:W99	12.1307	14.03	Yes	Yes	1	5	9
19	B:B:L79	B:B:L95	100	5.54	Yes	Yes	12	7	8
20	B:B:L95	B:B:Y124	100	5.86	Yes	Yes	0	8	6
21	B:B:R68	B:B:Y85	100	14.4	No	No	0	5	4
22	B:B:Y85	G:G:P60	100	11.13	No	No	0	4	9
23	B:B:M325	G:G:P60	100	6.71	Yes	No	0	5	9
24	B:B:M325	G:G:P49	100	6.71	Yes	No	0	5	7
25	G:G:D48	G:G:P49	100	3.22	Yes	No	0	9	7
26	B:B:S279	G:G:D48	100	8.83	No	Yes	0	9	9
27	B:B:L284	B:B:S279	100	6.01	No	No	0	5	9
28	B:B:L284	B:B:V296	100	4.47	No	Yes	0	5	5
29	B:B:M45	B:B:V296	100	3.04	Yes	Yes	0	4	5
30	B:B:L308	B:B:M45	100	7.07	No	Yes	0	7	4
31	B:B:C294	B:B:L308	100	6.35	Yes	No	0	5	7
32	B:B:C294	B:B:V315	100	5.12	Yes	No	14	5	7
33	B:B:H311	B:B:V315	100	4.15	Yes	No	14	9	7
34	B:B:D333	B:B:H311	100	7.56	Yes	Yes	14	9	9
35	B:B:D312	B:B:D333	100	7.98	No	Yes	0	5	9
36	B:B:D312	R:R:K616	100	5.53	No	No	0	5	7
37	R:R:K612	R:R:K616	100	10.06	No	No	0	7	7
38	R:R:K612	R:R:K615	100	5.75	No	Yes	3	7	8
39	R:R:K615	R:R:S620	100	3.06	Yes	No	3	8	8
40	R:R:S617	R:R:S620	100	3.26	No	No	3	8	8
41	R:R:S617	R:R:T619	100	4.8	No	No	3	8	8
42	R:R:R685	R:R:T619	100	12.94	Yes	No	3	8	8
43	R:R:L681	R:R:R685	100	4.86	No	Yes	0	7	8
44	R:R:L681	R:R:T622	100	7.37	No	No	0	7	7
45	R:R:T622	W:W:?1	100	4.85	No	Yes	0	7	0
46	R:R:M677	W:W:?1	100	8.14	Yes	Yes	3	6	0
47	R:R:L676	R:R:M677	100	4.24	Yes	Yes	0	7	6
48	R:R:I754	R:R:L676	100	7.14	No	Yes	0	9	7
49	R:R:I754	R:R:N758	100	4.25	No	No	0	9	9
50	R:R:L800	R:R:N758	100	10.98	No	No	0	9	9
51	R:R:L796	R:R:L800	100	6.92	No	No	0	9	9
52	R:R:L796	R:R:V762	100	4.47	No	No	0	9	8
53	R:R:L802	R:R:V762	100	4.47	No	No	0	7	8
54	R:R:L802	R:R:T797	100	8.84	No	No	0	7	9
55	R:R:L793	R:R:T797	100	2.95	No	No	0	7	9
56	R:R:L766	R:R:L793	100	5.54	No	No	0	7	7
57	R:R:L766	R:R:V789	100	4.47	No	Yes	0	7	8
58	R:R:L769	R:R:V789	100	2.98	No	Yes	0	7	8
59	R:R:L769	R:R:S792	100	3	No	No	0	7	8
60	A:A:L353	R:R:S792	100	7.51	No	No	0	7	8
61	A:A:L348	A:A:L353	100	6.92	No	No	0	9	7
62	A:A:F354	A:A:L348	100	8.53	Yes	No	0	5	9
63	A:A:F354	A:A:K345	100	6.2	Yes	No	0	5	5
64	A:A:D341	A:A:K345	100	8.3	No	No	0	8	5
65	A:A:D341	A:A:Y320	100	5.75	No	Yes	0	8	7
66	A:A:A338	A:A:Y320	44.1369	5.34	No	Yes	0	6	7
67	A:A:A338	A:A:I265	42.7996	4.87	No	No	0	6	8
68	A:A:I222	A:A:I265	40.1249	5.89	No	No	0	7	8
69	A:A:I222	A:A:L36	38.7876	7.14	No	Yes	0	7	7
70	B:B:Y85	G:G:F61	100	8.25	No	Yes	0	4	8
71	B:B:M325	G:G:F61	100	3.73	Yes	Yes	0	5	8
72	B:B:C294	B:B:T329	100	5.07	Yes	Yes	14	5	8
73	B:B:H311	B:B:T329	100	6.85	Yes	Yes	14	9	8
74	B:B:L308	B:B:W339	100	10.25	No	Yes	0	7	9
75	B:B:T329	B:B:W339	100	4.85	Yes	Yes	0	8	9
76	B:B:K337	B:B:W339	100	6.96	No	Yes	0	6	9
77	B:B:H311	B:B:K337	100	10.48	Yes	No	0	9	6
78	R:R:R685	R:R:Y684	100	10.29	Yes	Yes	3	8	8
79	R:R:L688	R:R:Y684	100	7.03	No	Yes	3	6	8
80	R:R:L688	W:W:?1	100	9.11	No	Yes	3	6	0
81	R:R:H691	R:R:Y684	100	6.53	Yes	Yes	3	7	8
82	R:R:H691	W:W:?1	100	5.29	Yes	Yes	3	7	0
83	R:R:M693	R:R:Y684	100	7.18	No	Yes	3	5	8
84	R:R:M693	W:W:?1	100	3.49	No	Yes	3	5	0
85	R:R:I680	W:W:?1	100	5.87	No	Yes	0	8	0
86	R:R:I680	R:R:L676	100	4.28	No	Yes	0	8	7
87	A:A:F196	A:A:L36	32.1002	3.65	Yes	Yes	8	7	7
88	A:A:F215	B:B:W99	19.3552	13.03	Yes	Yes	1	9	9
89	A:A:F215	A:A:L37	13.3352	4.87	Yes	No	0	9	9
90	A:A:L37	A:A:L39	12.123	6.92	No	No	0	9	9
91	A:A:Y320	R:R:V774	100	5.05	Yes	No	2	7	5
92	A:A:F334	R:R:V774	100	5.24	Yes	No	0	3	5
93	A:A:F267	A:A:F334	52.1421	5.36	Yes	Yes	0	9	3
94	A:A:F267	A:A:I49	22.7288	7.54	Yes	Yes	10	9	7
95	A:A:C224	A:A:I49	21.3921	4.91	No	Yes	10	7	7
96	A:A:C224	A:A:K46	40.1103	4.85	No	Yes	10	7	9
97	A:A:F267	A:A:N269	24.0658	3.62	Yes	Yes	10	9	9
98	A:A:C224	A:A:N269	21.3921	3.15	No	Yes	10	7	9
99	A:A:E318	A:A:Y320	100	8.98	No	Yes	2	4	7
100	A:A:E318	R:R:R780	100	9.3	No	No	2	4	3
101	A:A:E308	R:R:R780	100	4.65	No	No	2	3	3
102	A:A:E308	A:A:T321	96.1861	4.23	No	No	2	3	5
103	A:A:L266	A:A:T321	93.5302	5.9	No	No	2	9	5
104	A:A:F250	A:A:L266	42.7514	3.65	Yes	No	2	9	9
105	A:A:Y320	R:R:R777	100	11.32	Yes	Yes	2	7	5
106	R:R:R777	R:R:R780	100	8.53	Yes	No	2	5	3
107	A:A:K46	A:A:S44	29.4145	3.06	Yes	No	0	9	9
108	A:A:D226	A:A:S44	24.0665	1.47	No	No	0	8	9
109	A:A:D226	A:A:D229	13.3704	2.66	No	No	0	8	8
110	A:A:D229	A:A:R242	10.6964	4.76	No	Yes	0	8	9
111	A:A:F334	A:A:H322	62.8043	24.89	Yes	No	0	3	9
112	A:A:H322	A:A:K330	10.6925	6.55	No	No	0	9	4
113	B:B:L117	B:B:W99	100	5.69	Yes	Yes	1	9	9
114	A:A:Q204	B:B:L117	100	3.99	Yes	Yes	1	9	9
115	A:A:F196	A:A:F336	14.7134	3.22	Yes	Yes	8	7	8
116	A:A:W211	B:B:L117	100	5.69	Yes	Yes	1	9	9
117	A:A:Q204	B:B:Y145	100	5.64	Yes	Yes	1	9	8
118	A:A:W211	B:B:Y145	100	8.68	Yes	Yes	1	9	8
119	B:B:D118	B:B:G115	72.6236	3.35	No	No	0	9	9
120	B:B:G115	B:B:L146	71.4144	3.42	No	Yes	0	9	7
121	B:B:H142	B:B:L146	29.0449	3.86	Yes	Yes	1	9	7
122	A:A:K210	B:B:Y145	100	3.58	Yes	Yes	1	9	8
123	A:A:K210	B:B:D246	100	4.15	Yes	Yes	1	9	9
124	B:B:Q75	B:B:W99	100	6.57	No	Yes	1	9	9
125	B:B:Q75	B:B:Y59	100	10.15	No	Yes	1	9	8
126	B:B:W332	B:B:Y59	100	11.58	Yes	Yes	1	9	8
127	A:A:E308	A:A:Q304	100	7.65	No	Yes	2	3	5
128	A:A:L268	A:A:Q304	37.4036	3.99	No	Yes	2	8	5
129	A:A:L268	A:A:V225	34.7384	4.47	No	No	2	8	7
130	A:A:F307	A:A:V225	29.3939	10.49	Yes	No	2	8	7
131	A:A:F250	A:A:F307	29.3957	6.43	Yes	Yes	2	9	8
132	A:A:F323	A:A:Q304	98.8693	7.03	Yes	Yes	2	4	5
133	A:A:F323	A:A:Y296	100	3.09	Yes	Yes	2	4	4
134	A:A:F274	A:A:Y296	100	4.13	Yes	Yes	2	9	4
135	A:A:H322	R:R:E776	50.7837	8.62	No	No	0	9	5
136	A:A:F323	R:R:E776	98.8918	9.33	Yes	No	0	4	5
137	A:A:F334	R:R:G775	52.1156	4.52	Yes	No	0	3	6
138	R:R:E776	R:R:G775	50.78	3.27	No	No	0	5	6
139	A:A:F274	A:A:L227	10.6887	8.53	Yes	No	0	9	7
140	A:A:F274	A:A:Y230	74.8162	5.16	Yes	Yes	2	9	8
141	A:A:F274	A:A:I278	32.0639	8.79	Yes	Yes	2	9	6
142	A:A:L283	A:A:Y230	16.0321	7.03	No	Yes	2	7	8
143	A:A:F307	A:A:M243	48.0948	3.73	Yes	No	0	8	8
144	A:A:M243	A:A:Y287	42.7509	4.79	No	Yes	0	8	7
145	A:A:Y230	A:A:Y287	42.7543	5.96	Yes	Yes	2	8	7
146	A:A:H244	A:A:Y287	10.6876	5.44	No	Yes	0	4	7
147	A:A:I264	A:A:L266	48.1065	4.28	Yes	No	2	6	9
148	A:A:I264	A:A:K317	40.0919	5.82	Yes	Yes	0	6	7
149	A:A:C254	A:A:K317	10.6913	3.23	No	Yes	0	5	7
150	A:A:K317	A:A:R313	24.0554	3.71	Yes	Yes	0	7	4
151	B:B:R314	B:B:W332	100	19.99	No	Yes	0	8	9
152	A:A:E275	A:A:Y296	21.3771	12.35	No	Yes	0	5	4
153	A:A:E275	A:A:E276	16.0328	3.81	No	No	0	5	5
154	A:A:I278	A:A:N294	21.377	2.83	Yes	No	0	6	3
155	A:A:N294	A:A:P282	16.0328	3.26	No	No	0	3	5
156	A:A:A291	A:A:L283	10.6885	4.73	No	No	0	3	7
157	A:A:E289	A:A:Y287	64.1255	6.73	No	Yes	0	6	7
158	A:A:E289	A:A:Y302	42.7504	4.49	No	No	0	6	6
159	A:A:E297	A:A:Y296	32.0656	1.12	No	Yes	0	4	4
160	A:A:E297	A:A:T295	26.7214	9.88	No	No	0	4	5
161	A:A:S293	A:A:T295	21.3771	4.8	No	No	0	3	5
162	A:A:E298	A:A:S293	16.0328	5.75	No	No	0	4	3
163	A:A:E298	A:A:G292	10.6886	4.91	No	No	0	4	7
164	A:A:Q306	A:A:Y302	32.0628	14.65	No	No	0	5	6
165	A:A:C305	A:A:Q306	21.3752	1.53	No	No	0	3	5
166	A:A:C305	A:A:D309	10.6876	4.67	No	No	0	3	4
167	B:B:D246	B:B:S227	100	4.42	Yes	No	0	9	6
168	B:B:D247	B:B:S227	100	8.83	No	No	0	9	6
169	B:B:D247	B:B:E226	100	12.99	No	No	0	9	3
170	B:B:E226	B:B:R251	100	3.49	No	Yes	0	3	8
171	B:B:F253	B:B:R251	100	4.28	Yes	Yes	7	6	8
172	B:B:F222	B:B:F253	100	11.79	Yes	Yes	7	8	6
173	B:B:D258	B:B:F222	100	4.78	Yes	Yes	7	7	8
174	B:B:D258	B:B:R22	100	9.53	Yes	No	0	7	6
175	B:B:I18	B:B:R22	100	5.01	No	No	0	7	6
176	B:B:I18	G:G:L19	100	1.43	No	No	0	7	9
177	B:B:L14	G:G:L19	100	5.54	No	No	0	8	9
178	B:B:L14	B:B:Q13	100	6.65	No	No	0	8	1
179	B:B:E10	B:B:Q13	77.5355	5.1	No	No	0	8	1
180	B:B:E10	B:B:Q6	53.306	2.55	No	No	0	8	1
181	B:B:L7	B:B:Q6	43.6141	5.32	No	No	0	8	1
182	B:B:L7	G:G:R13	33.9222	2.43	No	No	0	8	6
183	G:G:I9	G:G:R13	24.2302	8.77	No	No	0	2	6
184	B:B:L4	G:G:I9	14.5381	9.99	No	No	0	4	2
185	B:B:D247	B:B:S245	100	4.42	No	No	0	9	9
186	B:B:H225	B:B:S245	100	15.34	Yes	No	7	9	9
187	B:B:F253	B:B:H225	100	3.39	Yes	Yes	7	6	9
188	B:B:N16	B:B:Q13	29.0762	1.32	No	No	0	1	1
189	B:B:N16	B:B:R19	14.5381	12.05	No	No	0	1	4
190	B:B:S316	B:B:Y59	100	3.82	No	Yes	1	9	8
191	B:B:S316	B:B:T274	100	3.2	No	No	0	9	8
192	B:B:D290	B:B:T274	100	5.78	Yes	No	0	6	8
193	B:B:C271	B:B:D290	100	3.11	No	Yes	0	5	6
194	B:B:C271	B:B:Y289	100	5.38	No	Yes	6	5	7
195	B:B:W297	B:B:Y289	100	6.75	Yes	Yes	6	8	7
196	B:B:L285	B:B:W297	100	4.56	Yes	Yes	6	6	8
197	B:B:F278	B:B:L285	97.0836	7.31	Yes	Yes	6	7	6
198	B:B:F235	B:B:F278	48.542	9.65	Yes	Yes	6	6	7
199	B:B:F235	G:G:Y40	38.834	5.16	Yes	Yes	6	6	6
200	B:B:N237	G:G:Y40	63.1053	10.47	No	Yes	0	5	6
201	B:B:N237	B:B:N239	58.2511	8.17	No	No	0	5	2
202	B:B:N239	B:B:R256	53.3969	15.67	No	No	0	2	9
203	B:B:R256	G:G:I28	43.6885	8.77	No	No	0	9	4
204	G:G:A33	G:G:I28	38.8343	3.25	No	No	0	7	4
205	B:B:D254	G:G:A33	33.98	4.63	No	No	0	9	7
206	B:B:D254	B:B:L261	24.2715	4.07	No	No	0	9	5
207	B:B:L261	G:G:V30	19.4172	2.98	No	No	0	5	8
208	B:B:D290	B:B:R314	100	25.01	Yes	No	0	6	8
209	B:B:F278	B:B:P236	43.6878	4.33	Yes	Yes	6	7	7
210	B:B:P236	G:G:Y40	38.8338	5.56	Yes	Yes	6	7	6
211	B:B:W297	B:B:Y264	36.4037	11.58	Yes	Yes	6	8	5
212	B:B:M262	B:B:Y264	29.1266	10.78	Yes	Yes	6	4	5
213	B:B:L30	B:B:M262	19.4179	5.65	No	Yes	0	5	4
214	B:B:L30	G:G:A34	16.9907	4.73	No	No	0	5	6
215	B:B:I33	G:G:A34	14.5635	1.62	No	No	0	3	6
216	B:B:I33	G:G:S31	12.1363	1.55	No	No	0	3	9
217	B:B:H62	B:B:Y105	15.2362	3.27	No	Yes	0	6	6
218	B:B:H62	B:B:R150	14.9867	14.67	No	No	0	6	6
219	B:B:C121	B:B:L146	25.4246	3.17	No	Yes	1	8	7
220	B:B:C121	B:B:L139	24.2129	6.35	No	No	0	8	9
221	B:B:I123	B:B:L139	23.02	4.28	No	No	0	6	9
222	B:B:H142	B:B:W169	14.5776	8.46	Yes	Yes	1	9	8
223	B:B:I157	B:B:W169	14.5522	3.52	No	Yes	0	7	8
224	B:B:F151	B:B:I157	12.1297	10.05	Yes	No	0	9	7
225	B:B:L146	B:B:T159	15.7382	7.37	Yes	Yes	1	7	9
226	B:B:T159	B:B:W169	14.5278	10.92	Yes	Yes	1	9	8
227	B:B:I123	B:B:Y111	15.755	4.84	No	Yes	13	6	4
228	B:B:H225	B:B:T243	26.6511	8.21	Yes	No	7	9	8
229	B:B:I232	B:B:T243	24.2294	3.04	Yes	No	0	8	8
230	B:B:I232	B:B:S191	19.3832	3.1	Yes	No	0	8	8
231	B:B:F241	B:B:F253	100	9.65	Yes	Yes	7	6	6
232	B:B:F241	B:B:V200	72.686	10.49	Yes	No	0	6	6
233	B:B:F234	B:B:V200	33.9209	7.87	No	No	0	5	6
234	B:B:F234	B:B:S191	16.9607	7.93	No	No	0	5	8
235	B:B:A193	B:B:F234	43.6114	4.16	Yes	No	0	4	5
236	B:B:A193	B:B:D195	21.8065	3.09	Yes	No	0	4	5
237	B:B:F222	B:B:Q220	38.7655	7.03	Yes	No	7	8	7
238	B:B:L210	B:B:Q220	33.9235	3.99	Yes	No	0	5	7
239	B:B:L198	B:B:L210	14.5389	6.92	No	Yes	0	3	5
240	B:B:L210	B:B:V200	33.9207	4.47	Yes	No	0	5	6
241	B:B:F241	B:B:L255	38.7658	3.65	Yes	No	0	6	6
242	B:B:L210	B:B:L255	33.9201	8.3	Yes	No	0	5	6
243	B:B:A193	B:B:P194	14.5377	1.87	Yes	No	0	4	4
244	B:B:D195	B:B:R197	14.5377	4.76	No	No	0	5	5
245	B:B:L210	B:B:R219	72.6868	2.43	Yes	No	0	5	5
246	B:B:D212	B:B:R219	58.1495	5.96	No	No	0	9	5
247	B:B:D212	B:B:E215	43.6121	5.2	No	No	0	9	3
248	B:B:E215	B:B:M217	29.0748	5.41	No	No	0	3	3
249	B:B:I273	B:B:Y289	16.99	9.67	Yes	Yes	0	6	7
250	B:B:I269	B:B:Y289	12.1352	6.04	No	Yes	0	4	7
251	B:B:N295	B:B:Y289	12.1345	10.47	Yes	Yes	6	6	7
252	B:B:E10	G:G:V16	19.3842	2.85	No	No	0	8	7
253	B:B:A11	G:G:V16	14.5381	1.7	No	No	0	5	7
254	R:R:W674	W:W:?1	100	3.75	Yes	Yes	3	9	0
255	R:R:W674	R:R:Y707	100	7.72	Yes	Yes	3	9	9
256	R:R:S670	R:R:Y707	100	3.82	No	Yes	0	8	9
257	R:R:P710	R:R:S670	100	3.56	No	No	0	9	8
258	R:R:L669	R:R:P710	100	3.28	Yes	No	0	9	9
259	R:R:H665	R:R:L669	100	9	Yes	Yes	0	9	9
260	R:R:H665	R:R:L735	100	3.86	Yes	Yes	0	9	9
261	R:R:L735	R:R:L744	57.4842	4.15	Yes	Yes	9	9	8
262	R:R:L744	R:R:W737	44.1313	6.83	Yes	No	0	8	6
263	R:R:P575	R:R:W737	40.1196	20.27	Yes	No	0	6	6
264	R:R:P575	R:R:S574	36.1133	3.56	Yes	Yes	11	6	9
265	R:R:L705	R:R:M677	100	5.65	No	Yes	0	6	6
266	R:R:F673	R:R:L705	100	6.09	No	No	0	8	6
267	R:R:F673	R:R:P710	100	11.56	No	No	0	8	9
268	R:R:S574	R:R:V577	16.0506	3.23	Yes	Yes	11	9	3
269	R:R:F747	R:R:H665	100	6.79	Yes	Yes	0	8	9
270	R:R:F747	R:R:L572	18.7251	3.65	Yes	Yes	9	8	9
271	R:R:F569	R:R:L572	16.0504	6.09	Yes	Yes	9	9	9
272	R:R:F569	R:R:T589	12.0391	6.49	Yes	No	0	9	9
273	R:R:F747	R:R:Y668	32.0988	4.13	Yes	Yes	9	8	8
274	R:R:D638	R:R:Y668	28.0966	4.6	Yes	Yes	0	7	8
275	R:R:H820	R:R:S574	14.713	4.18	Yes	Yes	11	8	9
276	R:R:L744	R:R:V748	12.0348	4.47	Yes	No	0	8	7
277	R:R:F672	R:R:F747	44.1263	7.5	Yes	Yes	0	9	8
278	R:R:A751	R:R:F672	22.7343	5.55	No	Yes	0	9	9
279	R:R:F823	R:R:M573	13.3712	7.46	No	Yes	0	9	9
280	R:R:F672	R:R:W804	14.7106	16.04	Yes	Yes	0	9	9
281	R:R:P578	R:R:V577	13.3756	3.53	Yes	Yes	0	4	3
282	R:R:H820	R:R:P578	13.3756	4.58	Yes	Yes	0	8	4
283	R:R:I581	R:R:P578	21.4011	6.77	Yes	Yes	0	4	4
284	R:R:T589	R:R:Y590	10.7015	2.5	No	Yes	0	9	5
285	R:R:P798	R:R:T797	17.3888	3.5	No	No	0	9	9
286	R:R:F833	R:R:P798	16.0513	2.89	No	No	0	7	9
287	R:R:F832	R:R:F833	14.7137	6.43	No	No	0	5	7
288	R:R:D638	R:R:S596	12.0436	4.42	Yes	No	0	7	9
289	R:R:G831	R:R:S596	10.7055	3.71	No	No	0	9	9
290	R:R:D638	R:R:L634	13.3802	8.14	Yes	No	0	7	9
291	R:R:L600	R:R:L634	12.0437	4.15	No	No	0	9	9
292	R:R:H665	R:R:S714	32.0968	4.18	Yes	No	0	9	9
293	R:R:F666	R:R:S714	13.3729	9.25	No	No	0	7	9
294	R:R:F662	R:R:S714	17.3893	3.96	No	No	0	8	9
295	R:R:F662	R:R:F663	16.0518	5.36	No	No	0	8	8
296	R:R:F663	R:R:W640	14.7142	16.04	No	No	0	8	6
297	R:R:A660	R:R:W640	12.039	2.59	No	No	0	7	6
298	R:R:A660	R:R:G644	10.7014	1.95	No	No	0	7	6
299	R:R:H665	R:R:T717	30.7501	5.48	Yes	No	0	9	9
300	R:R:T717	R:R:Y727	29.4132	4.99	No	Yes	0	9	9
301	R:R:V661	R:R:Y727	24.0735	6.31	No	Yes	0	8	9
302	R:R:K728	R:R:V661	21.3987	3.04	Yes	No	0	5	8
303	R:R:L735	R:R:Y727	29.4319	5.86	Yes	Yes	9	9	9
304	R:R:T721	R:R:Y727	24.0735	3.75	Yes	Yes	0	9	9
305	R:R:L735	R:R:P743	13.378	3.28	Yes	No	0	9	8
306	R:R:P743	R:R:T721	12.0403	12.24	No	Yes	0	8	9
307	R:R:S741	R:R:T721	28.0885	3.2	No	Yes	0	8	9
308	R:R:S741	R:R:T726	24.0759	3.2	No	Yes	0	8	4
309	R:R:S738	R:R:T726	12.038	3.2	No	Yes	0	2	4
310	R:R:A751	R:R:L752	12.0412	1.58	No	No	0	9	8
311	R:R:I808	R:R:L752	10.7034	4.28	No	No	0	7	8
312	R:R:F806	R:R:F823	16.0433	4.29	No	No	0	8	9
313	B:B:M217	G:G:M21	14.5374	1.44	No	No	0	3	1
314	A:A:E289	A:A:Q288	10.6876	1.27	No	No	0	6	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L681	R:R:T622	7.37	0	No	No	7	7	2	1
R:R:T622	W:W:?1	4.85	0	No	Yes	7	0	1	0
R:R:I625	R:R:M699	4.37	0	No	No	7	7	1	2
R:R:I625	W:W:?1	4.7	0	No	Yes	7	0	1	0
R:R:C626	R:R:L678	3.17	0	No	No	7	8	1	2
R:R:C626	W:W:?1	3.92	0	No	Yes	7	0	1	0
R:R:N629	R:R:W674	25.99	3	No	Yes	9	9	2	1
R:R:F703	R:R:N629	8.46	3	Yes	No	8	9	2	2
R:R:N629	R:R:Y707	4.65	3	No	Yes	9	9	2	2
R:R:M677	R:R:W674	4.65	3	Yes	Yes	6	9	1	1
R:R:F703	R:R:W674	8.02	3	Yes	Yes	8	9	2	1
R:R:G706	R:R:W674	4.22	0	No	Yes	9	9	2	1
R:R:W674	R:R:Y707	7.72	3	Yes	Yes	9	9	1	2
R:R:W674	W:W:?1	3.75	3	Yes	Yes	9	0	1	0
R:R:L676	R:R:M677	4.24	0	Yes	Yes	7	6	2	1
R:R:I680	R:R:L676	4.28	0	No	Yes	8	7	1	2
R:R:G702	R:R:M677	3.49	3	No	Yes	7	6	1	1
R:R:L705	R:R:M677	5.65	0	No	Yes	6	6	2	1
R:R:M677	W:W:?1	8.14	3	Yes	Yes	6	0	1	0
R:R:I680	W:W:?1	5.87	0	No	Yes	8	0	1	0
R:R:A683	R:R:V761	3.39	0	No	No	6	8	1	2
R:R:L688	R:R:Y684	7.03	3	No	Yes	6	8	1	2
R:R:H691	R:R:Y684	6.53	3	Yes	Yes	7	8	1	2
R:R:M693	R:R:Y684	7.18	3	No	Yes	5	8	1	2
R:R:I687	R:R:L764	4.28	0	No	No	6	7	1	2
R:R:I687	W:W:?1	9.39	0	No	Yes	6	0	1	0
R:R:H691	R:R:L688	6.43	3	Yes	No	7	6	1	1
R:R:L688	W:W:?1	9.11	3	No	Yes	6	0	1	0
R:R:H691	R:R:M693	9.19	3	Yes	No	7	5	1	1
R:R:H691	W:W:?1	5.29	3	Yes	Yes	7	0	1	0
R:R:M693	W:W:?1	3.49	3	No	Yes	5	0	1	0
R:R:F703	R:R:M699	6.22	3	Yes	No	8	7	2	2
R:R:G702	W:W:?1	5.63	3	No	Yes	7	0	1	0
R:R:F703	R:R:Y707	3.09	3	Yes	Yes	8	9	2	2
R:R:A683	W:W:?1	2.59	0	No	Yes	6	0	1	0
R:R:V701	W:W:?1	2.45	0	No	Yes	6	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
56.25	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/β1/γ2
46.67	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
40.00	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/β1/γ2
23.53	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
23.53	Single	9JCQ	LPC	9JCQ-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
21.43	Single	5XSZ	Glyceryl-mono-oleate	5XSZ-LPA₆-Glyceryl-mono-oleate
20.00	Single	5KW2	PubChem 133053953	5KW2-FFA1-PubChem 133053953
20.00	Single	9IYB	A1D5Q	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
17.65	Single	9CM3	Compound 187	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
17.65	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
17.65	Single	9K1C	DHA	9K1C-FFA1-DHA-Gi1/β1/γ2
16.67	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
16.67	Single	8Y72	BMS-986122	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
15.79	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
15.00	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
14.29	Single	9CM7	AZ-1729	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
13.64	Single	8XXV	A1D5Q	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
11.11	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
11.11	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
11.11	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
11.11	Single	8K9L	BMS-986122	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
11.11	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
10.53	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
10.00	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
6.67	Single	4PXF	Octyl-Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl-β-D-Glucopyranoside-Arrestin1 Finger Loop
6.25	Single	9JCQ	LPC	9JCQ-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
5.88	Single	6KQI	Org27569	6KQI-CB₁-CP55940-Org27569
5.88	Single	9NS9	Compound 187	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
5.56	Single	6OBA	GTPL11074	6OBA-β₂-S-Alprenolol-GTPL11074
5.56	Single	8WG8	Peptide	8WG8-Glucagon-Peptide-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8XXU	A1D5Q	8XXU-DP₂-A1D5Q-Gi1/β1/γ2
5.56	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
5.00	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/β1/γ2
4.76	Single	8IYX	YL-365	8IYX-GPR34-YL-365

PDB Summary
PDB	7WU5
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRF1
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	K6G
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3
Date	2022-04-27
D.O.I.	doi.org/10.1038/s41586-022-04580-w

Net Summary
I_min	3.04
Number of Linked Nodes	851
Number of Links	1050
Number of Hubs	164
Number of Links mediated by Hubs	608
Number of Communities	24
Number of Nodes involved in Communities	234
Number of Links involved in Communities	353

Path Summary
Number Of Nodes in MetaPath	315
Number Of Links MetaPath	314
Number of Shortest Paths	142208846
Length Of Smallest Path	3
Average Path Length	128
Length of Longest Path	96
Minimum Path Strength	1.46
Average Path Strength	8.0253
Maximum Path Strength	22.7367
Minimum Path Correlation	0.71
Average Path Correlation	1
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.63934
Average % Of Corr. Nodes	64.7743
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	64.2557
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cell surface receptor signaling pathway • regulation of lipid metabolic process • primary metabolic process • metabolic process • regulation of metabolic process • lipid metabolic process • regulation of primary metabolic process • fat cell differentiation • cellular developmental process • cell differentiation • behavior • learning or memory • cognition • memory • nervous system development • cellular component organization • cellular component biogenesis • cell junction organization • cellular component assembly • cell junction assembly • synapse organization • cellular component organization or biogenesis • synapse assembly • energy derivation by oxidation of organic compounds • energy reserve metabolic process • generation of precursor metabolites and energy • plasma membrane bounded cell projection organization • cell projection organization • cell development • neuron projection development • generation of neurons • neurogenesis • neuron differentiation • neuron development • cytoplasmic vesicle • intracellular vesicle
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	K6G
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	K6G
Name	[(2~{R})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] hexadecanoate
Synonyms
Identifier
Formula	C24 H51 N O7 P
Molecular Weight	496.638
SMILES
PubChem
Formal Charge	0
Total Atoms	84
Total Chiral Atoms	1
Total Bonds	83
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>7WU5_Chain_A K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A D N S G K S T I V K Q M T G I V E T H F T F K D L H F K M F D V G G Q R S E R K K W I H C F E D V A A I I F C V D L S D Y N R M H E S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y Q E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C A T D T K N A Q F I F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>7WU5_Chain_B S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>7WU5_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q5T601
Sequence	>7WU5_Chain_R A S F S I L M S P F V P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W K Q I K K S Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V D T T V N P S G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L V F H H M A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q P S N T Y K R K D V C W L N W S N G S K P L L A F V V P A L A I V A V N F V V V L L V L T K L W R P T V G E R L S R D D K A T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S Q N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L R Q L L F N K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8G2Y	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC	chim(Gs-CtGq)/β1/γ2	3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	8G2Y (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC		3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	7WU3	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gs/β1/γ2	3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU3 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WXU	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXU (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1L-G13)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-G12)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	Gi1/β1/γ2	3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4

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