psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:K25	A:A:K28	25.86	No	No	0	5	4
2	A:A:K25	A:A:Q29	6.78	No	No	0	5	4
3	A:A:E27	A:A:I26	6.83	No	Yes	8	6	9
4	A:A:I26	A:A:L30	2.85	Yes	No	8	9	5
5	A:A:I26	B:B:K89	4.36	Yes	Yes	8	9	9
6	A:A:I26	B:B:A92	3.25	Yes	No	0	9	6
7	A:A:E27	B:B:K89	6.75	No	Yes	8	6	9
8	A:A:K28	A:A:K32	2.87	No	No	0	4	4
9	A:A:K32	A:A:Q29	6.78	No	No	0	4	4
10	A:A:D33	A:A:Q29	2.61	No	No	0	5	4
11	A:A:L30	B:B:L55	2.77	No	No	0	5	6
12	A:A:L30	B:B:K89	2.82	No	Yes	8	5	9
13	A:A:D33	B:B:K78	11.06	No	No	0	5	8
14	A:A:K34	A:A:R38	7.43	No	No	3	4	4
15	A:A:K34	B:B:L55	5.64	No	No	0	4	6
16	A:A:K34	R:R:Q695	5.42	No	No	3	4	6
17	A:A:R42	A:A:Y37	12.35	Yes	Yes	1	9	4
18	A:A:D240	A:A:Y37	3.45	Yes	Yes	1	6	4
19	A:A:Y37	B:B:A56	4	Yes	No	0	4	7
20	A:A:Y37	B:B:Q75	3.38	Yes	Yes	1	4	9
21	A:A:Y37	B:B:D76	3.45	Yes	Yes	0	4	9
22	A:A:R38	R:R:H692	7.9	No	No	0	4	6
23	A:A:R38	R:R:Q695	11.68	No	No	3	4	6
24	A:A:H41	A:A:V217	2.77	Yes	Yes	9	6	5
25	A:A:F219	A:A:H41	4.53	Yes	Yes	9	8	6
26	A:A:H41	A:A:I383	2.65	Yes	Yes	9	6	8
27	A:A:H41	R:R:F690	7.92	Yes	Yes	9	6	8
28	A:A:H41	R:R:H692	3.58	Yes	No	0	6	6
29	A:A:F222	A:A:R42	5.34	Yes	Yes	0	7	9
30	A:A:D240	A:A:R42	4.76	Yes	Yes	1	6	9
31	A:A:R42	B:B:Q75	5.84	Yes	Yes	1	9	9
32	A:A:L43	A:A:M221	5.65	No	Yes	0	7	8
33	A:A:I375	A:A:L43	5.71	No	No	0	9	7
34	A:A:F238	A:A:L44	13.4	Yes	Yes	1	9	9
35	A:A:L44	A:A:V241	2.98	Yes	No	1	9	9
36	A:A:I244	A:A:L44	4.28	No	Yes	0	8	9
37	A:A:K53	A:A:L45	7.05	No	No	19	9	8
38	A:A:D223	A:A:L45	5.43	No	No	19	9	8
39	A:A:I245	A:A:L45	5.71	Yes	No	0	7	8
40	A:A:I244	A:A:L46	2.85	No	No	0	8	8
41	A:A:A48	A:A:S51	3.42	No	Yes	0	8	9
42	A:A:A48	A:A:R265	4.15	No	No	0	8	9
43	A:A:D249	A:A:N50	14.81	Yes	No	20	8	9
44	A:A:D252	A:A:N50	4.04	Yes	No	20	8	9
45	A:A:S51	A:A:V247	3.23	Yes	Yes	0	9	7
46	A:A:D249	A:A:S51	2.94	Yes	Yes	0	8	9
47	A:A:G52	A:A:N292	3.39	No	Yes	0	9	9
48	A:A:D223	A:A:K53	8.3	No	No	19	9	9
49	A:A:K53	A:A:V247	3.04	No	Yes	0	9	7
50	A:A:I56	A:A:T55	4.56	Yes	No	0	7	9
51	A:A:F290	A:A:I56	2.51	Yes	Yes	13	9	7
52	A:A:I56	A:A:N292	5.66	Yes	Yes	13	7	9
53	A:A:I56	A:A:T364	3.04	Yes	Yes	13	7	9
54	A:A:I56	A:A:N371	8.5	Yes	No	13	7	9
55	A:A:E209	A:A:I207	4.1	No	No	0	9	9
56	A:A:F222	A:A:I207	2.51	Yes	No	0	7	9
57	A:A:D223	A:A:F208	4.78	No	No	0	9	5
58	A:A:E209	A:A:H220	4.92	No	No	0	9	7
59	A:A:M221	A:A:T210	6.02	Yes	No	0	8	7
60	A:A:H220	A:A:K211	5.24	No	No	0	7	4
61	A:A:F212	A:A:F219	8.57	No	Yes	0	9	8
62	A:A:F212	A:A:M221	2.49	No	Yes	0	9	8
63	A:A:N218	A:A:Q213	17.17	No	No	0	4	3
64	A:A:F219	A:A:V214	3.93	Yes	No	9	8	6
65	A:A:R373	A:A:V214	3.92	No	No	9	5	6
66	A:A:F376	A:A:V214	3.93	Yes	No	9	8	6
67	A:A:D215	A:A:F376	8.36	No	Yes	0	5	8
68	A:A:F219	A:A:V217	3.93	Yes	Yes	9	8	5
69	A:A:F376	A:A:V217	2.62	Yes	Yes	9	8	5
70	A:A:V217	R:R:F690	3.93	Yes	Yes	9	5	8
71	A:A:F219	A:A:F376	3.22	Yes	Yes	9	8	8
72	A:A:C379	A:A:F219	4.19	No	Yes	0	8	8
73	A:A:F222	A:A:H220	9.05	Yes	No	0	7	7
74	A:A:I245	A:A:M221	2.92	Yes	Yes	0	7	8
75	A:A:F222	B:B:W99	18.04	Yes	Yes	0	7	9
76	A:A:Q227	A:A:V224	2.87	Yes	No	1	9	9
77	A:A:V224	A:A:W234	4.9	No	Yes	1	9	9
78	A:A:Q227	A:A:W234	6.57	Yes	Yes	1	9	9
79	A:A:Q227	B:B:L117	3.99	Yes	Yes	1	9	9
80	A:A:Q227	B:B:N119	6.6	Yes	No	1	9	9
81	A:A:Q227	B:B:G144	4.93	Yes	No	1	9	8
82	A:A:Q227	B:B:Y145	4.51	Yes	Yes	1	9	8
83	A:A:E230	A:A:R228	5.82	No	No	0	9	9
84	A:A:R228	B:B:T164	5.17	No	No	0	9	6
85	A:A:R228	B:B:D186	3.57	No	Yes	0	9	9
86	A:A:D229	A:A:R231	3.57	No	No	0	8	9
87	A:A:E230	A:A:R232	6.98	No	No	1	9	8
88	A:A:E230	A:A:K233	6.75	No	Yes	1	9	9
89	A:A:R231	A:A:W234	7	No	Yes	0	9	9
90	A:A:L272	A:A:R231	8.5	No	No	0	8	9
91	A:A:K233	A:A:R232	3.71	Yes	No	1	9	8
92	A:A:R232	B:B:D228	11.91	No	Yes	1	8	9
93	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
94	A:A:K233	B:B:D186	19.36	Yes	Yes	1	9	9
95	A:A:K233	B:B:M188	5.76	Yes	Yes	1	9	8
96	A:A:K233	B:B:C204	6.47	Yes	Yes	1	9	7
97	A:A:F238	A:A:W234	3.01	Yes	Yes	1	9	9
98	A:A:Q236	A:A:W281	6.57	No	No	1	8	5
99	A:A:Q236	B:B:R314	4.67	No	Yes	1	8	8
100	A:A:C237	B:B:Y59	9.41	No	Yes	0	8	8
101	A:A:C237	B:B:M101	4.86	No	Yes	0	8	9
102	A:A:F238	A:A:V241	2.62	Yes	No	1	9	9
103	A:A:F238	B:B:W99	8.02	Yes	Yes	1	9	9
104	A:A:F238	B:B:L117	3.65	Yes	Yes	1	9	9
105	A:A:N239	B:B:K57	9.79	No	Yes	1	8	9
106	A:A:N239	B:B:W332	11.3	No	Yes	1	8	9
107	A:A:D240	B:B:K57	2.77	Yes	Yes	1	6	9
108	A:A:D240	B:B:Q75	7.83	Yes	Yes	1	6	9
109	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
110	A:A:I244	A:A:I285	2.94	No	No	0	8	7
111	A:A:F290	A:A:I245	2.51	Yes	Yes	0	9	7
112	A:A:I245	A:A:I375	2.94	Yes	No	0	7	9
113	A:A:F246	A:A:V248	5.24	No	Yes	0	9	7
114	A:A:F246	A:A:I276	3.77	No	No	0	9	8
115	A:A:F290	A:A:V247	2.62	Yes	Yes	0	9	7
116	A:A:N292	A:A:V247	4.43	Yes	Yes	0	9	7
117	A:A:A269	A:A:V248	3.39	No	Yes	0	9	7
118	A:A:L291	A:A:V248	2.98	Yes	Yes	0	8	7
119	A:A:F345	A:A:V248	6.55	Yes	Yes	0	8	7
120	A:A:D249	A:A:D252	3.99	Yes	Yes	20	8	8
121	A:A:D249	A:A:K293	9.68	Yes	No	0	8	9
122	A:A:Q294	A:A:S250	5.78	Yes	No	0	6	6
123	A:A:L297	A:A:S250	6.01	No	No	0	8	6
124	A:A:L296	A:A:S251	9.01	No	No	0	6	9
125	A:A:L297	A:A:S251	4.5	No	No	0	8	9
126	A:A:K300	A:A:S251	4.59	No	No	0	9	9
127	A:A:D252	A:A:N264	4.04	Yes	No	0	8	9
128	A:A:D252	A:A:R265	10.72	Yes	No	0	8	9
129	A:A:L297	A:A:Y253	3.52	No	No	0	8	8
130	A:A:N264	A:A:Y311	12.79	No	No	0	9	6
131	A:A:E268	A:A:R265	10.47	No	No	0	9	9
132	A:A:F312	A:A:L266	3.65	No	No	0	8	8
133	A:A:I341	A:A:L266	5.71	No	No	0	8	8
134	A:A:L270	A:A:Q267	2.66	No	No	0	6	4
135	A:A:N271	A:A:Q267	9.24	No	No	0	5	4
136	A:A:E344	A:A:L270	2.65	Yes	No	0	5	6
137	A:A:F345	A:A:L270	8.53	Yes	No	0	8	6
138	A:A:F273	A:A:W277	8.02	Yes	Yes	5	9	6
139	A:A:F273	A:A:V287	3.93	Yes	No	5	9	6
140	A:A:F273	A:A:F345	7.5	Yes	Yes	0	9	8
141	A:A:F273	A:A:I348	2.51	Yes	No	0	9	4
142	A:A:F273	A:A:S349	2.64	Yes	Yes	5	9	7
143	A:A:C359	A:A:F273	2.79	Yes	Yes	5	5	9
144	A:A:I348	A:A:K274	8.72	No	No	0	4	5
145	A:A:V287	A:A:W277	3.68	No	Yes	5	6	6
146	A:A:S349	A:A:W277	3.71	Yes	Yes	5	7	6
147	A:A:H357	A:A:W277	24.33	No	Yes	0	7	6
148	A:A:C359	A:A:W277	3.92	Yes	Yes	5	5	6
149	A:A:N278	A:A:S352	2.98	No	No	0	8	5
150	A:A:L282	A:A:N279	6.87	No	No	0	9	8
151	A:A:W281	B:B:R314	13.99	No	Yes	1	5	8
152	A:A:I285	A:A:L282	2.85	No	No	0	7	9
153	A:A:H357	A:A:R283	6.77	No	No	0	7	3
154	A:A:R356	A:A:T284	3.88	No	No	0	2	4
155	A:A:S286	A:A:Y360	2.54	No	Yes	21	8	8
156	A:A:I382	A:A:S286	9.29	Yes	No	21	6	8
157	A:A:F290	A:A:I288	2.51	Yes	Yes	0	9	9
158	A:A:D378	A:A:I288	11.2	No	Yes	0	7	9
159	A:A:I288	A:A:I382	2.94	Yes	Yes	0	9	6
160	A:A:L289	A:A:L291	4.15	No	Yes	0	9	8
161	A:A:F345	A:A:L289	6.09	Yes	No	0	8	9
162	A:A:C359	A:A:L289	3.17	Yes	No	0	5	9
163	A:A:F290	A:A:H362	5.66	Yes	No	0	9	9
164	A:A:F290	A:A:T364	5.19	Yes	Yes	13	9	9
165	A:A:L291	A:A:Q294	5.32	Yes	Yes	5	8	6
166	A:A:F363	A:A:L291	4.87	Yes	Yes	5	5	8
167	A:A:N292	A:A:T364	4.39	Yes	Yes	13	9	9
168	A:A:K293	A:A:L296	4.23	No	No	0	9	6
169	A:A:K338	A:A:Q294	6.78	No	Yes	5	5	6
170	A:A:F363	A:A:Q294	10.54	Yes	Yes	5	5	6
171	A:A:R333	A:A:V301	2.62	No	No	0	5	7
172	A:A:V301	A:A:V334	3.21	No	No	0	7	4
173	A:A:E314	A:A:F312	13.99	Yes	No	18	6	8
174	A:A:F312	A:A:F340	6.43	No	Yes	18	8	7
175	A:A:E314	A:A:P313	6.29	Yes	No	0	6	6
176	A:A:E314	A:A:F340	7	Yes	Yes	18	6	7
177	A:A:E314	A:A:E344	6.34	Yes	Yes	18	6	5
178	A:A:F315	A:A:R336	14.97	No	No	0	6	5
179	A:A:F315	A:A:F340	12.86	No	Yes	0	6	7
180	A:A:P321	A:A:Y318	5.56	No	No	0	5	6
181	A:A:F340	A:A:Y318	10.32	Yes	No	0	7	6
182	A:A:D343	A:A:Y318	11.49	No	No	0	3	6
183	A:A:P321	A:A:T320	3.5	No	No	0	5	1
184	A:A:R336	A:A:T320	3.88	No	No	0	5	1
185	A:A:P321	A:A:Y339	4.17	No	Yes	0	5	3
186	A:A:K338	A:A:V334	3.04	No	No	0	5	4
187	A:A:T335	A:A:Y339	2.5	No	Yes	0	4	3
188	A:A:F363	A:A:K338	7.44	Yes	No	5	5	5
189	A:A:R342	A:A:Y339	8.23	Yes	Yes	5	4	3
190	A:A:F363	A:A:Y339	4.13	Yes	Yes	5	5	3
191	A:A:E344	A:A:F340	7	Yes	Yes	18	5	7
192	A:A:F345	A:A:I341	2.51	Yes	No	0	8	8
193	A:A:L346	A:A:R342	7.29	No	Yes	5	4	4
194	A:A:P361	A:A:R342	5.76	No	Yes	5	5	4
195	A:A:F363	A:A:R342	7.48	Yes	Yes	5	5	4
196	A:A:E344	A:A:R347	6.98	Yes	No	0	5	4
197	A:A:L346	A:A:S349	6.01	No	Yes	5	4	7
198	A:A:L346	A:A:P361	6.57	No	No	5	4	5
199	A:A:S349	A:A:T350	4.8	Yes	No	0	7	4
200	A:A:C359	A:A:S349	3.44	Yes	Yes	5	5	7
201	A:A:D354	A:A:G355	6.71	No	No	0	3	2
202	A:A:R356	A:A:R389	5.33	No	No	0	2	5
203	A:A:Y358	A:A:Y360	2.98	No	Yes	0	4	8
204	A:A:C359	A:A:P361	3.77	Yes	No	5	5	5
205	A:A:D378	A:A:Y360	9.2	No	Yes	0	7	8
206	A:A:D381	A:A:Y360	5.75	No	Yes	0	8	8
207	A:A:I382	A:A:Y360	8.46	Yes	Yes	21	6	8
208	A:A:H362	A:A:R374	10.16	No	No	0	9	4
209	A:A:D378	A:A:H362	10.08	No	No	0	7	9
210	A:A:D368	A:A:T364	8.67	No	Yes	13	9	9
211	A:A:N371	A:A:T364	7.31	No	Yes	13	9	9
212	A:A:R374	A:A:T364	2.59	No	Yes	0	4	9
213	A:A:D368	A:A:E370	5.2	No	No	0	9	4
214	A:A:D368	A:A:N371	9.42	No	No	13	9	9
215	A:A:E370	A:A:T369	4.23	No	No	0	4	9
216	A:A:F376	A:A:R373	4.28	Yes	No	9	8	5
217	A:A:F376	A:A:N377	6.04	Yes	No	0	8	4
218	A:A:F376	A:A:K380	6.2	Yes	No	9	8	7
219	A:A:F376	R:R:F690	7.5	Yes	Yes	9	8	8
220	A:A:K380	R:R:V689	3.04	No	No	9	7	9
221	A:A:K380	R:R:F690	6.2	No	Yes	9	7	8
222	A:A:D381	A:A:Q385	3.92	No	No	0	8	5
223	A:A:I382	A:A:M386	2.92	Yes	No	0	6	4
224	A:A:I383	A:A:N387	2.83	Yes	No	0	8	8
225	A:A:I383	R:R:V689	3.07	Yes	No	9	8	9
226	A:A:I383	R:R:F690	3.77	Yes	Yes	9	8	8
227	A:A:L384	A:A:L388	2.77	No	Yes	0	6	8
228	A:A:N387	R:R:R685	9.64	No	No	0	8	8
229	A:A:L388	A:A:L393	2.77	Yes	Yes	0	8	8
230	A:A:L388	A:A:V394	2.98	Yes	No	0	8	8
231	A:A:L388	R:R:I686	2.85	Yes	Yes	0	8	7
232	A:A:R389	A:A:V394	14.38	No	No	0	5	8
233	A:A:E390	R:R:S620	4.31	No	No	0	4	8
234	A:A:Y391	R:R:T619	2.5	Yes	Yes	0	4	8
235	A:A:Y391	R:R:R623	10.29	Yes	No	0	4	9
236	A:A:Y391	R:R:L678	4.69	Yes	Yes	0	4	8
237	A:A:Y391	R:R:L681	4.69	Yes	Yes	0	4	7
238	A:A:Y391	R:R:L682	10.55	Yes	No	0	4	9
239	A:A:N392	R:R:D842	10.77	No	No	0	7	9
240	A:A:L393	R:R:S792	3	Yes	No	0	8	8
241	A:A:L393	R:R:L796	8.3	Yes	No	22	8	9
242	B:B:I43	B:B:M45	4.37	No	Yes	0	3	4
243	B:B:L308	B:B:M45	7.07	Yes	Yes	0	7	4
244	B:B:M45	B:B:N340	2.8	Yes	No	0	4	9
245	B:B:M45	G:G:L50	5.65	Yes	No	0	4	9
246	B:B:K337	B:B:T47	4.5	Yes	No	6	6	3
247	B:B:T47	B:B:W339	7.28	No	Yes	6	3	9
248	B:B:R48	B:B:R49	3.2	Yes	No	15	7	7
249	B:B:A326	B:B:R48	4.15	No	Yes	15	7	7
250	B:B:I338	B:B:R48	6.26	No	Yes	15	5	7
251	B:B:N340	B:B:R48	4.82	No	Yes	15	9	7
252	B:B:R49	B:B:T87	3.88	No	No	0	7	5
253	B:B:I338	B:B:R49	2.51	No	No	15	5	7
254	B:B:R52	B:B:T50	9.06	No	No	6	7	3
255	B:B:F335	B:B:T50	2.59	No	No	6	4	3
256	B:B:K337	B:B:T50	4.5	Yes	No	6	6	3
257	B:B:L51	B:B:W82	15.94	Yes	Yes	0	9	9
258	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
259	B:B:L336	B:B:L51	5.54	Yes	Yes	0	7	9
260	B:B:I338	B:B:L51	4.28	No	Yes	0	5	9
261	B:B:F335	B:B:R52	11.76	No	No	6	4	7
262	B:B:G53	B:B:W82	2.81	No	Yes	0	9	9
263	B:B:H54	B:B:I58	7.95	Yes	No	8	9	9
264	B:B:H54	B:B:S72	4.18	Yes	Yes	8	9	9
265	B:B:H54	B:B:S74	12.55	Yes	No	0	9	9
266	B:B:H54	B:B:I80	9.28	Yes	Yes	8	9	8
267	B:B:H54	B:B:W82	7.41	Yes	Yes	8	9	9
268	B:B:H54	B:B:S334	4.18	Yes	No	0	9	4
269	B:B:H54	B:B:L336	3.86	Yes	Yes	8	9	7
270	B:B:D76	B:B:L55	10.86	Yes	No	0	9	6
271	B:B:K57	B:B:Y59	11.94	Yes	Yes	1	9	8
272	B:B:K57	B:B:Q75	6.78	Yes	Yes	1	9	9
273	B:B:K57	B:B:W332	8.12	Yes	Yes	1	9	9
274	B:B:G330	B:B:I58	3.53	No	No	0	5	9
275	B:B:I58	B:B:L336	7.14	No	Yes	8	9	7
276	B:B:Q75	B:B:Y59	10.15	Yes	Yes	1	9	8
277	B:B:W332	B:B:Y59	3.86	Yes	Yes	1	9	8
278	B:B:L70	B:B:M61	5.65	No	No	0	5	6
279	B:B:M61	B:B:S72	3.07	No	Yes	0	6	9
280	B:B:C317	B:B:M61	6.48	No	No	0	7	6
281	B:B:H62	B:B:R150	4.51	No	Yes	0	6	6
282	B:B:L70	B:B:W63	9.11	No	Yes	24	5	7
283	B:B:S84	B:B:W63	6.18	No	Yes	24	5	7
284	B:B:T321	B:B:W63	10.92	No	Yes	0	7	7
285	B:B:A328	B:B:W63	5.19	No	Yes	0	5	7
286	B:B:I81	B:B:L69	4.28	Yes	No	11	7	5
287	B:B:L69	B:B:Y105	3.52	No	Yes	11	5	6
288	B:B:L70	B:B:S84	3	No	No	24	5	5
289	B:B:L79	B:B:V71	2.98	Yes	No	11	7	8
290	B:B:V71	B:B:Y105	7.57	No	Yes	11	8	6
291	B:B:V112	B:B:V71	3.21	No	No	11	8	8
292	B:B:S72	B:B:W82	4.94	Yes	Yes	8	9	9
293	B:B:L336	B:B:S72	9.01	Yes	Yes	8	7	9
294	B:B:A73	B:B:V100	3.39	No	No	0	9	9
295	B:B:A73	B:B:C103	3.61	No	No	0	9	8
296	B:B:D76	B:B:S74	4.42	Yes	No	0	9	9
297	B:B:Q75	B:B:W99	9.86	Yes	Yes	1	9	9
298	B:B:D76	B:B:G77	3.35	Yes	No	0	9	8
299	B:B:D76	B:B:K78	8.3	Yes	No	0	9	8
300	B:B:I80	B:B:K78	2.91	Yes	No	0	8	8
301	B:B:L79	B:B:L95	5.54	Yes	Yes	11	7	8
302	B:B:L79	B:B:V112	2.98	Yes	No	11	7	8
303	B:B:C114	B:B:L79	3.17	No	Yes	11	8	7
304	B:B:I80	B:B:W82	9.4	Yes	Yes	8	8	9
305	B:B:I80	B:B:K89	2.91	Yes	Yes	8	8	9
306	B:B:H91	B:B:I81	11.93	No	Yes	0	5	7
307	B:B:I81	B:B:I93	2.94	Yes	No	0	7	7
308	B:B:I81	B:B:Y105	4.84	Yes	Yes	11	7	6
309	B:B:I81	B:B:L126	4.28	Yes	No	0	7	5
310	B:B:K89	B:B:W82	13.92	Yes	Yes	8	9	9
311	B:B:D83	B:B:T86	10.12	No	No	0	8	6
312	B:B:D83	B:B:V90	4.38	No	No	0	8	5
313	B:B:N88	B:B:T86	8.77	No	No	0	7	6
314	B:B:H91	B:B:V90	5.54	No	No	0	5	5
315	B:B:I93	B:B:P94	3.39	No	No	0	7	5
316	B:B:I93	B:B:V133	3.07	No	No	0	7	4
317	B:B:P94	B:B:R134	2.88	No	No	0	5	3
318	B:B:L95	B:B:V100	2.98	Yes	No	11	8	9
319	B:B:C114	B:B:L95	4.76	No	Yes	11	8	8
320	B:B:L95	B:B:Y124	8.21	Yes	No	0	8	6
321	B:B:I120	B:B:R96	2.51	Yes	No	25	6	6
322	B:B:E138	B:B:R96	11.63	Yes	No	25	6	6
323	B:B:D118	B:B:S97	8.83	No	No	0	9	8
324	B:B:L117	B:B:W99	3.42	Yes	Yes	1	9	9
325	B:B:C114	B:B:V100	3.42	No	No	11	8	9
326	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
327	B:B:L117	B:B:M101	2.83	Yes	Yes	1	9	9
328	B:B:M101	B:B:Y145	4.79	Yes	Yes	1	9	8
329	B:B:C149	B:B:T102	5.07	No	No	0	8	8
330	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
331	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
332	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
333	B:B:N110	B:B:S108	4.47	No	No	10	4	6
334	B:B:D154	B:B:S108	8.83	No	No	10	6	6
335	B:B:K127	B:B:N110	5.6	No	No	10	4	4
336	B:B:D154	B:B:N110	4.04	No	No	10	6	4
337	B:B:I123	B:B:Y111	6.04	Yes	Yes	10	6	4
338	B:B:N125	B:B:Y111	5.81	No	Yes	10	4	4
339	B:B:K127	B:B:Y111	7.17	No	Yes	10	4	4
340	B:B:S136	B:B:Y111	5.09	No	Yes	0	4	4
341	B:B:D154	B:B:Y111	9.2	No	Yes	10	6	4
342	B:B:L126	B:B:V112	5.96	No	No	0	5	8
343	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
344	B:B:L117	B:B:Y145	3.52	Yes	Yes	1	9	8
345	B:B:D118	B:B:I120	5.6	No	Yes	0	9	6
346	B:B:G144	B:B:N119	3.39	No	No	1	8	9
347	B:B:E138	B:B:I120	6.83	Yes	Yes	25	6	6
348	B:B:A140	B:B:I120	3.25	No	Yes	0	5	6
349	B:B:C121	B:B:L139	4.76	No	No	0	8	9
350	B:B:C121	B:B:L146	3.17	No	No	12	8	7
351	B:B:C121	B:B:T159	3.38	No	Yes	12	8	9
352	B:B:S122	B:B:Y124	6.36	No	No	0	8	6
353	B:B:E138	B:B:S122	4.31	Yes	No	0	6	8
354	B:B:F151	B:B:I123	5.02	Yes	Yes	10	9	6
355	B:B:I123	B:B:I171	4.42	Yes	No	10	6	6
356	B:B:V135	B:B:Y124	3.79	No	No	0	4	6
357	B:B:K127	B:B:N125	18.19	No	No	10	4	4
358	B:B:E138	B:B:V135	2.85	Yes	No	0	6	4
359	B:B:L139	B:B:W169	13.67	No	Yes	0	9	8
360	B:B:G141	B:B:W169	2.81	No	Yes	0	5	8
361	B:B:H142	B:B:L146	5.14	Yes	No	12	9	7
362	B:B:H142	B:B:T159	6.85	Yes	Yes	12	9	9
363	B:B:H142	B:B:S161	16.74	Yes	No	0	9	9
364	B:B:H142	B:B:T165	2.74	Yes	No	0	9	7
365	B:B:A167	B:B:H142	4.39	No	Yes	12	4	9
366	B:B:D163	B:B:T143	13.01	No	No	0	9	5
367	B:B:S147	B:B:Y145	10.17	No	Yes	0	9	8
368	B:B:G162	B:B:Y145	2.9	No	Yes	1	9	8
369	B:B:D186	B:B:Y145	4.6	Yes	Yes	1	9	8
370	B:B:M188	B:B:Y145	3.59	Yes	Yes	1	8	8
371	B:B:L146	B:B:T159	4.42	No	Yes	12	7	9
372	B:B:C148	B:B:R150	6.96	No	Yes	0	6	6
373	B:B:C149	B:B:I157	3.27	No	No	0	8	7
374	B:B:F151	B:B:I157	12.56	Yes	No	0	9	7
375	B:B:F151	B:B:I171	2.51	Yes	No	10	9	6
376	B:B:L152	B:B:V158	4.47	No	No	0	3	5
377	B:B:L152	B:B:L192	5.54	No	No	0	3	5
378	B:B:L152	B:B:V213	2.98	No	No	0	3	4
379	B:B:D153	B:B:N155	12.12	No	No	0	5	3
380	B:B:D153	B:B:Q156	10.44	No	No	0	5	5
381	B:B:L168	B:B:Q156	6.65	Yes	No	0	6	5
382	B:B:L168	B:B:V158	4.47	Yes	No	0	6	5
383	B:B:L190	B:B:V158	2.98	Yes	No	0	5	5
384	B:B:T159	B:B:W169	7.28	Yes	Yes	12	9	8
385	B:B:S160	B:B:V187	4.85	No	No	0	6	9
386	B:B:L190	B:B:S160	6.01	Yes	No	0	5	6
387	B:B:G162	B:B:S161	3.71	No	No	0	9	9
388	B:B:D163	B:B:S161	2.94	No	No	0	9	9
389	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
390	B:B:D163	B:B:T165	7.23	No	No	0	9	7
391	B:B:T165	B:B:T181	3.14	No	No	0	7	2
392	B:B:C166	B:B:F180	2.79	Yes	Yes	7	8	7
393	B:B:C166	B:B:V187	5.12	Yes	No	7	8	9
394	B:B:C166	B:B:F199	5.59	Yes	Yes	7	8	9
395	B:B:C166	B:B:S201	3.44	Yes	Yes	7	8	9
396	B:B:A167	B:B:W169	2.59	No	Yes	12	4	8
397	B:B:A167	B:B:Q176	4.55	No	No	12	4	4
398	B:B:L168	B:B:T178	4.42	Yes	No	7	6	4
399	B:B:F180	B:B:L168	4.87	Yes	Yes	7	7	6
400	B:B:G174	B:B:W169	2.81	No	Yes	0	4	8
401	B:B:Q176	B:B:W169	14.24	No	Yes	12	4	8
402	B:B:D170	B:B:T173	5.78	Yes	No	26	9	5
403	B:B:D170	B:B:Q175	2.61	Yes	No	26	9	4
404	B:B:D170	B:B:T177	4.34	Yes	No	0	9	4
405	B:B:Q175	B:B:T173	8.5	No	No	26	4	5
406	B:B:Q176	B:B:T179	9.92	No	No	0	4	4
407	B:B:F180	B:B:T178	9.08	Yes	No	7	7	4
408	B:B:F180	B:B:F199	10.72	Yes	Yes	7	7	9
409	B:B:F180	B:B:W211	12.03	Yes	Yes	7	7	8
410	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
411	B:B:G182	B:B:T181	3.64	No	No	0	6	2
412	B:B:H183	B:B:S201	2.79	Yes	Yes	0	9	9
413	B:B:A203	B:B:H183	8.78	No	Yes	0	8	9
414	B:B:H183	B:B:S207	5.58	Yes	No	0	9	5
415	B:B:H183	B:B:K209	17.03	Yes	Yes	0	9	6
416	B:B:D205	B:B:T184	5.78	No	No	0	9	3
417	B:B:D205	B:B:G185	5.03	No	No	0	9	5
418	B:B:C204	B:B:D186	6.22	Yes	Yes	1	7	9
419	B:B:S201	B:B:V187	4.85	Yes	No	7	9	9
420	B:B:C204	B:B:M188	4.86	Yes	Yes	1	7	8
421	B:B:M188	B:B:N230	2.8	Yes	No	0	8	9
422	B:B:I232	B:B:S189	3.1	Yes	No	0	8	7
423	B:B:F199	B:B:L190	6.09	Yes	Yes	0	9	5
424	B:B:I232	B:B:S191	4.64	Yes	No	0	8	8
425	B:B:F234	B:B:S191	3.96	Yes	No	0	5	8
426	B:B:A193	B:B:D195	3.09	No	No	0	4	5
427	B:B:A193	B:B:F234	4.16	No	Yes	0	4	5
428	B:B:F234	B:B:P194	2.89	Yes	No	2	5	4
429	B:B:G238	B:B:P194	4.06	No	No	2	7	4
430	B:B:D195	B:B:R197	3.57	No	Yes	16	5	5
431	B:B:D195	B:B:L198	4.07	No	Yes	16	5	3
432	B:B:L198	B:B:R197	4.86	Yes	Yes	16	3	5
433	B:B:D212	B:B:R197	16.68	Yes	Yes	16	9	5
434	B:B:R197	B:B:R219	4.26	Yes	No	16	5	5
435	B:B:L198	B:B:L210	2.77	Yes	Yes	0	3	5
436	B:B:L198	B:B:R219	4.86	Yes	No	16	3	5
437	B:B:F199	B:B:W211	10.02	Yes	Yes	7	9	8
438	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
439	B:B:L210	B:B:V200	4.47	Yes	Yes	0	5	6
440	B:B:I232	B:B:V200	4.61	Yes	Yes	2	8	6
441	B:B:F234	B:B:V200	10.49	Yes	Yes	2	5	6
442	B:B:F241	B:B:V200	6.55	Yes	Yes	2	6	6
443	B:B:S201	B:B:W211	7.41	Yes	Yes	7	9	8
444	B:B:G202	B:B:I229	3.53	No	Yes	2	6	7
445	B:B:G202	B:B:I232	3.53	No	Yes	2	6	8
446	B:B:C204	B:B:D228	7.78	Yes	Yes	1	7	9
447	B:B:D205	B:B:S207	4.42	No	No	0	9	5
448	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
449	B:B:K209	B:B:W211	15.08	Yes	Yes	7	6	8
450	B:B:C218	B:B:K209	6.47	No	Yes	7	5	6
451	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
452	B:B:K209	G:G:Q18	4.07	Yes	Yes	7	6	9
453	B:B:L210	B:B:Q220	7.99	Yes	Yes	0	5	7
454	B:B:L210	B:B:L255	9.69	Yes	No	0	5	6
455	B:B:C218	B:B:W211	2.61	No	Yes	7	5	8
456	B:B:D212	B:B:E215	5.2	Yes	No	0	9	3
457	B:B:D212	B:B:R219	7.15	Yes	No	16	9	5
458	B:B:E215	B:B:M217	4.06	No	No	0	3	3
459	B:B:M217	G:G:M21	4.33	No	No	0	3	1
460	B:B:C218	G:G:Q18	9.16	No	Yes	7	5	9
461	B:B:F222	B:B:Q220	3.51	Yes	Yes	2	8	7
462	B:B:D258	B:B:Q220	13.05	No	Yes	2	7	7
463	B:B:Q220	G:G:E22	6.37	Yes	No	0	7	9
464	B:B:Q220	G:G:I25	4.12	Yes	No	0	7	2
465	B:B:T221	G:G:E22	8.47	No	No	0	7	9
466	B:B:F222	B:B:F241	7.5	Yes	Yes	2	8	6
467	B:B:F222	B:B:F253	10.72	Yes	Yes	2	8	6
468	B:B:F222	B:B:L255	3.65	Yes	No	0	8	6
469	B:B:D258	B:B:F222	4.78	No	Yes	2	7	8
470	B:B:H225	B:B:I229	7.95	Yes	Yes	2	9	7
471	B:B:H225	B:B:T243	8.21	Yes	Yes	2	9	8
472	B:B:H225	B:B:S245	11.16	Yes	No	2	9	9
473	B:B:D247	B:B:H225	3.78	Yes	Yes	2	9	9
474	B:B:H225	B:B:R251	14.67	Yes	Yes	2	9	8
475	B:B:F253	B:B:H225	4.53	Yes	Yes	2	6	9
476	B:B:D247	B:B:E226	6.5	Yes	No	0	9	3
477	B:B:E226	B:B:R251	3.49	No	Yes	0	3	8
478	B:B:D228	B:B:S227	2.94	Yes	No	1	9	6
479	B:B:D246	B:B:S227	4.42	No	No	1	9	6
480	B:B:D228	B:B:D246	2.66	Yes	No	1	9	9
481	B:B:I229	B:B:I232	2.94	Yes	Yes	2	7	8
482	B:B:I229	B:B:T243	3.04	Yes	Yes	2	7	8
483	B:B:A231	B:B:V276	3.39	No	No	0	5	6
484	B:B:F241	B:B:I232	6.28	Yes	Yes	2	6	8
485	B:B:I232	B:B:T243	7.6	Yes	Yes	2	8	8
486	B:B:F234	B:B:G238	3.01	Yes	No	2	5	7
487	B:B:F235	B:B:P236	10.11	Yes	Yes	2	6	7
488	B:B:F235	B:B:N237	12.08	Yes	Yes	2	6	5
489	B:B:F235	B:B:F278	6.43	Yes	Yes	2	6	7
490	B:B:F235	G:G:L37	4.87	Yes	No	0	6	7
491	B:B:F235	G:G:Y40	4.13	Yes	Yes	2	6	6
492	B:B:F278	B:B:P236	2.89	Yes	Yes	2	7	7
493	B:B:G282	B:B:P236	4.06	No	Yes	2	9	7
494	B:B:P236	G:G:Y40	6.95	Yes	Yes	2	7	6
495	B:B:G238	B:B:N237	3.39	No	Yes	2	7	5
496	B:B:N237	B:B:N239	6.81	Yes	No	0	5	2
497	B:B:N237	G:G:Y40	8.14	Yes	Yes	2	5	6
498	B:B:F241	B:B:T243	3.89	Yes	Yes	2	6	8
499	B:B:F241	B:B:F253	6.43	Yes	Yes	2	6	6
500	B:B:A242	B:B:L252	3.15	No	No	0	4	7
501	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
502	B:B:F253	B:B:T243	7.78	Yes	Yes	2	6	8
503	B:B:G244	B:B:I273	5.29	No	No	0	5	6
504	B:B:D247	B:B:S245	10.31	Yes	No	2	9	9
505	B:B:D247	B:B:T249	10.12	Yes	Yes	2	9	6
506	B:B:R251	B:B:T249	3.88	Yes	Yes	2	8	6
507	B:B:T249	B:B:T263	3.14	Yes	No	2	6	1
508	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
509	B:B:C250	B:B:Y264	4.03	No	Yes	2	8	5
510	B:B:C250	B:B:I273	6.55	No	No	0	8	6
511	B:B:C250	B:B:L285	3.17	No	No	2	8	6
512	B:B:R251	B:B:T263	14.23	Yes	No	2	8	1
513	B:B:L252	B:B:Y264	3.52	No	Yes	0	7	5
514	B:B:D254	B:B:R256	3.57	Yes	No	0	9	9
515	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
516	B:B:D254	B:B:L261	9.5	Yes	No	0	9	5
517	B:B:D254	G:G:A33	3.09	Yes	No	0	9	7
518	B:B:R256	G:G:I28	5.01	No	No	0	9	4
519	B:B:E260	B:B:Q259	6.37	No	No	0	6	6
520	B:B:L285	B:B:Y264	4.69	No	Yes	2	6	5
521	B:B:W297	B:B:Y264	14.47	Yes	Yes	2	8	5
522	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
523	B:B:H266	B:B:N268	15.31	No	No	0	4	4
524	B:B:I269	B:B:Y289	3.63	No	Yes	0	4	7
525	B:B:C271	B:B:D291	6.22	No	No	0	5	8
526	B:B:I273	B:B:Y289	10.88	No	Yes	0	6	7
527	B:B:S275	B:B:T274	3.2	No	No	0	8	8
528	B:B:D290	B:B:T274	7.23	No	No	1	6	8
529	B:B:R314	B:B:T274	7.76	Yes	No	1	8	8
530	B:B:F278	B:B:G282	3.01	Yes	No	2	7	9
531	B:B:F278	B:B:L285	3.65	Yes	No	2	7	6
532	B:B:L284	B:B:S279	4.5	No	No	0	5	9
533	B:B:S279	G:G:D48	4.42	No	No	0	9	9
534	B:B:S279	G:G:L50	3	No	No	0	9	9
535	B:B:S281	G:G:D48	10.31	No	No	0	9	9
536	B:B:D298	B:B:R283	10.72	No	Yes	0	9	9
537	B:B:L300	B:B:R283	3.64	No	Yes	27	6	9
538	B:B:R283	G:G:C41	5.57	Yes	No	27	9	7
539	B:B:L284	B:B:V296	2.98	No	Yes	0	5	5
540	B:B:L286	B:B:V296	4.47	No	Yes	0	7	5
541	B:B:L286	B:B:V327	4.47	No	Yes	0	7	6
542	B:B:A287	B:B:Y289	2.67	No	Yes	2	6	7
543	B:B:A287	B:B:W297	2.59	No	Yes	2	6	8
544	B:B:C294	B:B:G288	3.92	Yes	No	6	5	7
545	B:B:G288	B:B:L318	3.42	No	No	6	7	6
546	B:B:N293	B:B:Y289	4.65	No	Yes	2	5	7
547	B:B:N295	B:B:Y289	5.81	No	Yes	2	6	7
548	B:B:W297	B:B:Y289	8.68	Yes	Yes	2	8	7
549	B:B:D290	B:B:R314	15.48	No	Yes	1	6	8
550	B:B:D291	B:B:N293	4.04	No	No	0	8	5
551	B:B:N293	B:B:N295	5.45	No	No	2	5	6
552	B:B:C294	B:B:L308	6.35	Yes	Yes	0	5	7
553	B:B:C294	B:B:V315	3.42	Yes	No	6	5	7
554	B:B:C294	B:B:L318	3.17	Yes	No	6	5	6
555	B:B:N295	B:B:R304	10.85	No	No	0	6	5
556	B:B:L308	B:B:V296	2.98	Yes	Yes	0	7	5
557	B:B:R304	B:B:W297	9	No	Yes	0	5	8
558	B:B:D298	B:B:K301	9.68	No	No	0	9	5
559	B:B:L300	G:G:M38	2.83	No	No	0	6	4
560	B:B:L300	G:G:C41	3.17	No	No	27	6	7
561	B:B:D303	B:B:K301	5.53	No	No	0	2	5
562	B:B:R304	B:B:V307	2.62	No	No	0	5	3
563	B:B:L308	B:B:W339	3.42	Yes	Yes	0	7	9
564	B:B:H311	B:B:V315	2.77	Yes	No	6	9	7
565	B:B:H311	B:B:T329	5.48	Yes	Yes	6	9	8
566	B:B:H311	B:B:S331	8.37	Yes	No	0	9	9
567	B:B:H311	B:B:K337	7.86	Yes	Yes	6	9	6
568	B:B:D312	B:B:D333	5.32	No	No	0	5	9
569	B:B:N313	B:B:W332	4.52	No	Yes	0	7	9
570	B:B:D333	B:B:N313	10.77	No	No	0	9	7
571	B:B:R314	B:B:W332	6	Yes	Yes	1	8	9
572	B:B:T329	B:B:V315	3.17	Yes	No	6	8	7
573	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
574	B:B:L318	B:B:T329	5.9	No	Yes	6	6	8
575	B:B:V320	B:B:V327	6.41	No	Yes	0	7	6
576	B:B:D323	B:B:T321	7.23	No	No	0	7	7
577	B:B:G324	B:B:T321	3.64	No	No	0	9	7
578	B:B:D322	B:B:D323	5.32	No	No	0	1	7
579	B:B:D323	B:B:M325	5.54	No	No	0	7	5
580	B:B:M325	G:G:P49	6.71	No	No	0	5	7
581	B:B:A326	B:B:N340	4.69	No	No	15	7	9
582	B:B:V327	B:B:W339	3.68	Yes	Yes	0	6	9
583	B:B:V327	G:G:L50	4.47	Yes	No	0	6	9
584	B:B:T329	B:B:W339	8.49	Yes	Yes	6	8	9
585	B:B:K337	B:B:W339	6.96	Yes	Yes	6	6	9
586	G:G:R13	G:G:V16	6.54	No	No	0	6	7
587	G:G:E17	G:G:R13	15.12	No	No	0	6	6
588	G:G:K14	G:G:Q18	6.78	No	Yes	0	4	9
589	G:G:M21	G:G:Q18	6.8	No	Yes	0	1	9
590	G:G:E22	G:G:Q18	2.55	No	Yes	0	9	9
591	G:G:K20	G:G:N24	6.99	No	No	0	6	1
592	G:G:I28	G:G:K32	7.27	No	No	0	4	5
593	G:G:D36	G:G:K32	12.44	No	No	0	5	5
594	G:G:D36	G:G:L37	5.43	No	No	0	5	7
595	G:G:E42	G:G:M38	2.71	No	No	0	1	4
596	G:G:H44	G:G:Y40	21.78	No	Yes	0	6	6
597	G:G:A43	G:G:H44	2.93	No	No	0	4	6
598	G:G:E47	G:G:H44	4.92	No	No	0	3	6
599	G:G:E47	G:G:K46	2.7	No	No	0	3	1
600	G:G:D48	G:G:P49	3.22	No	No	0	9	7
601	R:R:K586	R:R:T567	3	No	No	0	3	9
602	R:R:S568	R:R:V577	3.23	No	No	0	9	3
603	R:R:S568	R:R:V585	3.23	No	No	0	9	8
604	R:R:F569	R:R:T589	7.78	Yes	No	4	9	9
605	R:R:F569	R:R:L593	6.09	Yes	Yes	4	9	8
606	R:R:F569	R:R:Y668	3.09	Yes	Yes	4	9	8
607	R:R:F569	R:R:W804	3.01	Yes	Yes	4	9	9
608	R:R:F569	R:R:F823	3.22	Yes	Yes	4	9	9
609	R:R:F569	R:R:N827	3.62	Yes	Yes	4	9	9
610	R:R:S570	R:R:T810	3.2	No	Yes	4	9	7
611	R:R:H820	R:R:S570	13.95	Yes	No	4	8	9
612	R:R:I571	R:R:V577	4.61	No	No	0	7	3
613	R:R:F641	R:R:I571	5.02	Yes	No	0	9	7
614	R:R:I571	R:R:R729	10.02	No	No	0	7	5
615	R:R:F641	R:R:L572	3.65	Yes	No	0	9	9
616	R:R:L572	R:R:Y668	8.21	No	Yes	0	9	8
617	R:R:G807	R:R:M573	5.24	No	No	4	9	9
618	R:R:M573	R:R:T810	4.52	No	Yes	4	9	7
619	R:R:F823	R:R:M573	4.98	Yes	No	4	9	9
620	R:R:P575	R:R:S574	3.56	No	Yes	0	6	9
621	R:R:F576	R:R:S574	2.64	No	Yes	4	3	9
622	R:R:S574	R:R:T810	4.8	Yes	Yes	4	9	7
623	R:R:I811	R:R:S574	4.64	No	Yes	0	5	9
624	R:R:S574	R:R:S814	3.26	Yes	No	4	9	5
625	R:R:P575	R:R:W737	12.16	No	Yes	0	6	6
626	R:R:F576	R:R:S814	10.57	No	No	4	3	5
627	R:R:H820	R:R:P578	6.1	Yes	No	0	8	4
628	R:R:L817	R:R:T580	7.37	No	No	0	2	3
629	R:R:I581	R:R:V584	3.07	No	No	0	4	3
630	R:R:I581	R:R:L817	4.28	No	No	0	4	2
631	R:R:F582	R:R:P583	4.33	No	No	0	1	1
632	R:R:F582	R:R:K586	38.47	No	No	0	1	3
633	R:R:I588	R:R:L825	8.56	No	No	0	9	5
634	R:R:L593	R:R:T589	2.95	Yes	No	4	8	9
635	R:R:F829	R:R:G592	6.02	Yes	No	0	7	9
636	R:R:D638	R:R:L593	4.07	Yes	Yes	0	7	8
637	R:R:I642	R:R:L593	4.28	No	Yes	0	8	8
638	R:R:F829	R:R:I595	3.77	Yes	No	0	7	7
639	R:R:G831	R:R:S596	3.71	No	No	0	9	9
640	R:R:I597	R:R:L635	4.28	Yes	No	0	7	8
641	R:R:D638	R:R:I597	2.8	Yes	Yes	0	7	7
642	R:R:I597	R:R:V639	3.07	Yes	No	0	7	6
643	R:R:G598	R:R:I601	3.53	No	No	0	3	5
644	R:R:F832	R:R:S599	2.64	Yes	No	0	5	8
645	R:R:L835	R:R:S599	9.01	No	No	0	8	8
646	R:R:L600	R:R:L634	5.54	No	Yes	0	9	9
647	R:R:L600	R:R:L635	2.77	No	No	0	9	8
648	R:R:G831	R:R:L600	5.13	No	No	0	9	9
649	R:R:I601	R:R:I605	2.94	No	No	0	5	6
650	R:R:I601	R:R:L635	2.85	No	No	0	5	8
651	R:R:L602	R:R:L835	4.15	No	No	0	6	8
652	R:R:C603	R:R:E607	6.08	No	No	0	7	9
653	R:R:L604	R:R:L632	6.92	No	No	0	8	5
654	R:R:I606	R:R:I839	2.94	No	No	0	8	7
655	R:R:E607	R:R:R624	5.82	No	Yes	0	9	9
656	R:R:E607	R:R:M627	6.77	No	No	0	9	7
657	R:R:F610	R:R:R624	6.41	No	Yes	0	8	9
658	R:R:H621	R:R:W611	3.17	No	No	0	6	9
659	R:R:Q618	R:R:T619	2.83	No	Yes	0	7	8
660	R:R:R685	R:R:T619	19.41	No	Yes	0	8	8
661	R:R:H621	R:R:I625	3.98	No	No	3	6	7
662	R:R:H621	R:R:M699	2.63	No	Yes	3	6	7
663	R:R:L681	R:R:T622	2.95	Yes	No	0	7	7
664	R:R:M698	R:R:T622	3.01	No	No	0	8	7
665	R:R:R623	R:R:R624	4.26	No	Yes	0	9	9
666	R:R:R624	R:R:V628	2.62	Yes	No	0	9	7
667	R:R:I625	R:R:M699	2.92	No	Yes	3	7	7
668	R:R:I625	W:W:?1	3.6	No	Yes	3	7	0
669	R:R:C626	R:R:W674	2.61	No	Yes	0	7	9
670	R:R:C626	R:R:L678	3.17	No	Yes	0	7	8
671	R:R:C626	W:W:?1	2.67	No	Yes	0	7	0
672	R:R:L799	R:R:M627	7.07	Yes	No	0	6	7
673	R:R:N629	R:R:V628	2.96	No	No	0	9	7
674	R:R:N629	R:R:W674	18.08	No	Yes	3	9	9
675	R:R:F703	R:R:N629	3.62	No	No	3	8	9
676	R:R:I630	R:R:L671	2.85	No	Yes	28	8	7
677	R:R:I630	R:R:M675	5.83	No	Yes	28	8	9
678	R:R:I630	R:R:L799	2.85	No	Yes	0	8	6
679	R:R:S633	R:R:S670	4.89	No	No	0	8	8
680	R:R:L671	R:R:S633	4.5	Yes	No	0	7	8
681	R:R:D638	R:R:L634	6.79	Yes	Yes	0	7	9
682	R:R:L634	R:R:L671	5.54	Yes	Yes	0	9	7
683	R:R:L634	R:R:Q830	5.32	Yes	No	0	9	9
684	R:R:F667	R:R:I636	18.84	No	No	0	8	7
685	R:R:A637	R:R:Y668	9.34	No	Yes	0	9	8
686	R:R:D638	R:R:Y668	3.45	Yes	Yes	0	7	8
687	R:R:V643	R:R:W640	3.68	No	No	0	8	6
688	R:R:A660	R:R:W640	3.89	No	No	0	7	6
689	R:R:F663	R:R:W640	18.04	No	No	0	8	6
690	R:R:F641	R:R:T664	2.59	Yes	No	0	9	7
691	R:R:C657	R:R:K728	3.23	No	No	0	9	5
692	R:R:C657	R:R:C733	7.28	No	No	0	9	9
693	R:R:V661	R:R:Y727	5.05	No	Yes	0	8	9
694	R:R:F662	R:R:F663	7.5	No	No	0	8	8
695	R:R:F662	R:R:S714	6.61	No	No	0	8	9
696	R:R:F663	R:R:F667	4.29	No	No	0	8	8
697	R:R:T664	R:R:Y668	2.5	No	Yes	0	7	8
698	R:R:T664	R:R:W734	3.64	No	Yes	0	7	8
699	R:R:H665	R:R:L669	5.14	Yes	Yes	14	9	9
700	R:R:H665	R:R:T717	2.74	Yes	No	0	9	9
701	R:R:H665	R:R:L735	3.86	Yes	Yes	0	9	9
702	R:R:F747	R:R:H665	7.92	No	Yes	14	8	9
703	R:R:F666	R:R:F667	6.43	Yes	No	0	7	8
704	R:R:F666	R:R:P710	2.89	Yes	Yes	0	7	9
705	R:R:F666	R:R:L711	8.53	Yes	No	0	7	7
706	R:R:F666	R:R:S714	3.96	Yes	No	0	7	9
707	R:R:W804	R:R:Y668	4.82	Yes	Yes	4	9	8
708	R:R:L669	R:R:P710	3.28	Yes	Yes	14	9	9
709	R:R:F747	R:R:L669	3.65	No	Yes	14	8	9
710	R:R:L669	R:R:P750	3.28	Yes	No	0	9	9
711	R:R:P710	R:R:S670	3.56	Yes	No	0	9	8
712	R:R:F672	R:R:L671	4.87	No	Yes	0	9	7
713	R:R:L671	R:R:M675	2.83	Yes	Yes	28	7	9
714	R:R:A751	R:R:F672	4.16	No	No	0	9	9
715	R:R:F672	R:R:W804	19.04	No	Yes	0	9	9
716	R:R:C709	R:R:F673	5.59	No	No	14	8	8
717	R:R:F673	R:R:P710	10.11	No	Yes	14	8	9
718	R:R:F673	R:R:I754	3.77	No	No	0	8	9
719	R:R:G702	R:R:W674	2.81	Yes	Yes	3	7	9
720	R:R:F703	R:R:W674	3.01	No	Yes	3	8	9
721	R:R:G706	R:R:W674	4.22	No	Yes	0	9	9
722	R:R:W674	R:R:Y707	7.72	Yes	No	3	9	9
723	R:R:M675	R:R:N758	4.21	Yes	No	0	9	9
724	R:R:G801	R:R:M675	3.49	No	Yes	0	9	9
725	R:R:I754	R:R:L676	4.28	No	No	0	9	7
726	R:R:G702	R:R:M677	5.24	Yes	No	3	7	6
727	R:R:L705	R:R:M677	5.65	No	No	0	6	6
728	R:R:M677	W:W:?1	9.52	No	Yes	3	6	0
729	R:R:L678	R:R:L799	4.15	Yes	Yes	0	8	6
730	R:R:I680	W:W:?1	15.62	No	Yes	0	8	0
731	R:R:L681	R:R:R685	6.07	Yes	No	0	7	8
732	R:R:L681	W:W:?1	9.32	Yes	Yes	0	7	0
733	R:R:I686	R:R:L682	2.85	Yes	No	23	7	9
734	R:R:L682	R:R:V765	4.47	No	No	23	9	9
735	R:R:A683	R:R:V761	3.39	No	No	0	6	8
736	R:R:L688	R:R:Y684	5.86	No	Yes	3	6	8
737	R:R:M693	R:R:Y684	5.99	No	Yes	0	5	8
738	R:R:M698	R:R:Y684	4.79	No	Yes	3	8	8
739	R:R:Y684	W:W:?1	2.96	Yes	Yes	3	8	0
740	R:R:I686	R:R:V765	4.61	Yes	No	23	7	9
741	R:R:I686	R:R:K768	2.91	Yes	No	0	7	8
742	R:R:I687	R:R:L764	7.14	No	No	0	6	7
743	R:R:L688	W:W:?1	3.49	No	Yes	3	6	0
744	R:R:F690	R:R:V689	2.62	Yes	No	9	8	9
745	R:R:M699	R:R:Q695	2.72	Yes	No	3	7	6
746	R:R:L697	R:R:V701	2.98	No	No	0	3	6
747	R:R:M698	W:W:?1	9.52	No	Yes	3	8	0
748	R:R:G702	W:W:?1	2.88	Yes	Yes	3	7	0
749	R:R:F703	R:R:Y707	3.09	No	No	3	8	9
750	R:R:C709	R:R:P710	3.77	No	Yes	14	8	9
751	R:R:S714	R:R:V715	3.23	No	No	0	9	6
752	R:R:P743	R:R:T717	5.25	Yes	No	0	8	9
753	R:R:I718	R:R:Y727	13.3	No	Yes	0	7	9
754	R:R:Q722	R:R:T721	2.83	No	No	29	7	9
755	R:R:T721	R:R:Y727	6.24	No	Yes	29	9	9
756	R:R:Q722	R:R:Y727	5.64	No	Yes	29	7	9
757	R:R:R729	R:R:V732	14.38	No	No	0	5	4
758	R:R:R729	R:R:W734	4	No	Yes	0	5	8
759	R:R:D731	R:R:V732	4.38	No	No	0	3	4
760	R:R:L735	R:R:W734	13.67	Yes	Yes	0	9	8
761	R:R:F747	R:R:W734	9.02	No	Yes	0	8	8
762	R:R:L735	R:R:P743	6.57	Yes	Yes	0	9	8
763	R:R:L735	R:R:L744	4.15	Yes	No	0	9	8
764	R:R:N736	R:R:N739	4.09	No	No	0	8	4
765	R:R:G740	R:R:N736	5.09	No	No	0	4	8
766	R:R:S741	R:R:W737	6.18	No	Yes	0	8	6
767	R:R:L744	R:R:W737	6.83	No	Yes	0	8	6
768	R:R:L745	R:R:W737	3.42	No	Yes	0	8	6
769	R:R:I811	R:R:W737	3.52	No	Yes	0	5	6
770	R:R:G740	R:R:P743	6.09	No	Yes	0	4	8
771	R:R:K742	R:R:P743	3.35	No	Yes	0	7	8
772	R:R:L744	R:R:V748	2.98	No	No	0	8	7
773	R:R:L752	R:R:V748	4.47	No	No	0	8	7
774	R:R:I811	R:R:V748	3.07	No	No	0	5	7
775	R:R:P750	R:R:V749	5.3	No	No	0	9	7
776	R:R:I808	R:R:L752	5.71	No	No	0	7	8
777	R:R:I754	R:R:N758	4.25	No	No	0	9	9
778	R:R:G805	R:R:V755	3.68	No	No	0	6	8
779	R:R:L800	R:R:N758	8.24	Yes	No	0	9	9
780	R:R:L802	R:R:V762	4.47	No	No	0	7	8
781	R:R:L766	R:R:V789	2.98	No	No	0	7	8
782	R:R:L766	R:R:S792	4.5	No	No	0	7	8
783	R:R:L769	R:R:S792	3	No	No	0	7	8
784	R:R:R788	R:R:T785	15.52	No	No	0	7	7
785	R:R:K791	R:R:L841	2.82	No	No	0	8	5
786	R:R:L793	R:R:T797	2.95	No	No	0	7	9
787	R:R:F837	R:R:L794	12.18	No	No	0	8	6
788	R:R:L794	R:R:L841	4.15	No	No	0	6	5
789	R:R:G838	R:R:I795	3.53	No	No	0	8	7
790	R:R:P798	R:R:T797	3.5	Yes	No	0	9	9
791	R:R:F833	R:R:P798	2.89	Yes	Yes	17	7	9
792	R:R:F837	R:R:P798	2.89	No	Yes	17	8	9
793	R:R:L799	R:R:L800	2.77	Yes	Yes	0	6	9
794	R:R:L826	R:R:T803	8.84	No	No	0	6	9
795	R:R:N827	R:R:T803	4.39	Yes	No	0	9	9
796	R:R:F823	R:R:W804	4.01	Yes	Yes	4	9	9
797	R:R:N827	R:R:W804	15.82	Yes	Yes	4	9	9
798	R:R:Q830	R:R:W804	6.57	No	Yes	0	9	9
799	R:R:G807	R:R:T810	5.46	No	Yes	4	9	7
800	R:R:F823	R:R:G807	3.01	Yes	No	4	9	9
801	R:R:G809	R:R:I808	3.53	No	No	0	7	7
802	R:R:G809	R:R:W819	4.22	No	No	0	7	6
803	R:R:H820	R:R:T810	5.48	Yes	Yes	4	8	7
804	R:R:F823	R:R:T810	3.89	Yes	Yes	4	9	7
805	R:R:D813	R:R:N816	4.04	No	No	30	4	5
806	R:R:D813	R:R:W819	5.58	No	No	30	4	6
807	R:R:H820	R:R:S814	4.18	Yes	No	4	8	5
808	R:R:A818	R:R:N816	4.69	No	No	0	6	5
809	R:R:N816	R:R:W819	7.91	No	No	30	5	6
810	R:R:F823	R:R:N827	15.71	Yes	Yes	4	9	9
811	R:R:F829	R:R:L825	3.65	Yes	No	0	7	5
812	R:R:F829	R:R:F832	9.65	Yes	Yes	17	7	5
813	R:R:F829	R:R:F833	3.22	Yes	Yes	17	7	7
814	R:R:F832	R:R:F833	5.36	Yes	Yes	17	5	7
815	R:R:C836	R:R:F832	6.98	No	Yes	0	7	5
816	R:R:F833	R:R:F837	3.22	Yes	No	17	7	8
817	R:R:C836	R:R:L840	3.17	No	No	0	7	7
818	R:R:I839	R:R:L845	4.28	No	Yes	0	7	8
819	R:R:D842	R:R:K844	4.15	No	No	0	9	8
820	R:R:D842	R:R:L845	8.14	No	Yes	0	9	8
821	R:R:R846	R:R:S843	7.91	No	No	0	7	5
822	R:R:K844	R:R:L848	4.23	No	No	0	8	7
823	R:R:L845	R:R:L848	2.77	Yes	No	0	8	7
824	R:R:V591	R:R:W587	2.45	No	No	0	7	4
825	R:R:F610	R:R:L845	2.44	No	Yes	0	8	8
826	R:R:F806	R:R:L826	2.44	No	No	0	8	6
827	R:R:F833	R:R:L826	2.44	Yes	No	0	7	6
828	B:B:L190	B:B:R150	2.43	Yes	Yes	0	5	6
829	B:B:L192	B:B:R150	2.43	No	Yes	0	5	6
830	B:B:L284	B:B:R283	2.43	No	Yes	0	5	9
831	R:R:T785	R:R:W770	2.43	No	No	0	7	6
832	B:B:F292	B:B:N313	2.42	No	No	0	4	7
833	B:B:M262	B:B:Y264	2.39	No	Yes	0	4	5
834	B:B:D212	B:B:R214	2.38	Yes	No	0	9	9
835	B:B:I157	B:B:W169	2.35	No	Yes	0	7	8
836	B:B:E260	B:B:F253	2.33	No	Yes	0	6	6
837	B:B:H62	B:B:Y105	2.18	No	Yes	0	6	6
838	A:A:G225	A:A:G226	2.11	No	No	0	9	9
839	B:B:G115	B:B:G116	2.11	No	No	0	9	9
840	B:B:R48	B:B:Y85	2.06	Yes	No	0	7	4
841	B:B:A231	B:B:G244	1.95	No	No	0	5	5
842	B:B:A248	B:B:G272	1.95	No	No	0	5	4
843	B:B:A309	B:B:G310	1.95	No	No	0	3	5
844	R:R:A828	R:R:G592	1.95	No	No	0	8	9
845	R:R:A660	R:R:G644	1.95	No	No	0	7	6
846	B:B:A106	B:B:P107	1.87	No	No	0	6	6
847	A:A:G47	A:A:S51	1.86	No	Yes	0	9	9
848	A:A:G353	A:A:S352	1.86	No	No	0	4	5
849	B:B:G319	B:B:S277	1.86	No	No	0	5	5
850	B:B:G282	B:B:S281	1.86	No	No	0	9	9
851	B:B:G306	B:B:V296	1.84	No	Yes	0	4	5
852	B:B:G319	B:B:V320	1.84	No	No	0	5	7
853	R:R:G592	R:R:V591	1.84	No	No	0	9	7
854	R:R:G644	R:R:V647	1.84	No	No	0	6	5
855	R:R:G679	R:R:V761	1.84	No	No	0	9	8
856	R:R:G702	R:R:V701	1.84	Yes	No	0	7	6
857	R:R:G790	R:R:V789	1.84	No	No	0	5	8
858	R:R:G809	R:R:V812	1.84	No	No	0	7	6
859	R:R:G655	R:R:T658	1.82	No	No	0	3	6
860	B:B:A60	B:B:C103	1.81	No	No	0	7	8
861	R:R:A631	R:R:C603	1.81	No	No	0	8	7
862	R:R:A660	R:R:C657	1.81	No	No	0	7	9
863	R:R:G594	R:R:I597	1.76	No	Yes	0	5	7
864	R:R:P578	R:R:T580	1.75	No	No	0	4	3
865	R:R:P743	R:R:T721	1.75	Yes	No	0	8	9
866	B:B:G324	B:B:K280	1.74	No	No	0	9	1
867	B:B:G310	B:B:K337	1.74	No	Yes	0	5	6
868	A:A:C365	A:A:V367	1.71	No	No	0	8	9
869	B:B:C233	B:B:V276	1.71	No	No	0	3	6
870	R:R:G679	R:R:L678	1.71	No	Yes	0	9	8
871	R:R:G679	R:R:L800	1.71	No	Yes	0	9	9
872	R:R:G708	R:R:L711	1.71	No	No	0	6	7
873	A:A:A298	A:A:V334	1.7	No	No	0	4	4
874	B:B:A257	G:G:V30	1.7	No	No	0	7	8
875	B:B:A305	B:B:V296	1.7	No	Yes	0	4	5
876	R:R:A824	R:R:V585	1.7	No	No	0	8	8
877	A:A:C379	A:A:T242	1.69	No	No	0	8	8
878	R:R:I581	R:R:P583	1.69	No	No	0	4	1
879	R:R:I834	R:R:P798	1.69	No	Yes	0	9	9
880	A:A:D354	A:A:G353	1.68	No	No	0	3	4
881	B:B:D170	B:B:G174	1.68	Yes	No	0	9	4
882	A:A:G226	A:A:Q227	1.64	No	Yes	0	9	9
883	R:R:C709	R:R:I713	1.64	No	No	0	8	9
884	A:A:D331	A:A:P332	1.61	No	No	0	4	1
885	B:B:S207	B:B:T223	1.6	No	No	0	5	2
886	A:A:G353	A:A:H357	1.59	No	No	0	4	7
887	B:B:A240	B:B:L252	1.58	No	No	0	6	7
888	B:B:A240	G:G:L37	1.58	No	No	0	6	7
889	R:R:A631	R:R:L604	1.58	No	No	0	8	8
890	R:R:A608	R:R:L609	1.58	No	No	0	5	4
891	R:R:A694	R:R:L697	1.58	No	No	0	8	3
892	A:A:A366	A:A:D295	1.54	No	No	0	9	9
893	R:R:I588	R:R:V821	1.54	No	No	0	9	7
894	R:R:I716	R:R:V720	1.54	No	No	0	7	5
895	R:R:I822	R:R:V821	1.54	No	No	0	5	7
896	A:A:C365	A:A:Q294	1.53	No	Yes	0	8	6
897	B:B:F253	B:B:G224	1.51	Yes	No	0	6	6
898	B:B:G41	B:B:R42	1.5	No	No	0	1	2
899	R:R:K728	R:R:T658	1.5	No	No	0	5	6
900	A:A:L302	A:A:V301	1.49	No	No	0	2	7
901	R:R:L676	R:R:V757	1.49	No	No	0	7	7
902	R:R:L766	R:R:V762	1.49	No	No	0	7	8
903	R:R:L800	R:R:V762	1.49	Yes	No	0	9	8
904	R:R:I686	R:R:I687	1.47	Yes	No	0	7	6
905	A:A:N218	A:A:T40	1.46	No	No	0	4	7
906	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
907	R:R:I787	R:R:K791	1.45	No	No	0	4	8
908	R:R:Q847	R:R:S843	1.44	No	No	0	6	5
909	A:A:I235	A:A:L44	1.43	No	Yes	0	9	9
910	A:A:I235	A:A:L46	1.43	No	No	0	9	8
911	A:A:I235	A:A:L282	1.43	No	No	0	9	9
912	A:A:L393	R:R:I795	1.43	Yes	No	22	8	7
913	R:R:I795	R:R:L796	1.43	No	No	22	7	9
914	A:A:E390	R:R:T619	1.41	No	Yes	0	4	8
915	B:B:G64	B:B:W63	1.41	No	Yes	0	5	7
916	A:A:A372	A:A:F212	1.39	No	No	0	8	9
917	B:B:A299	B:B:F278	1.39	No	Yes	0	5	7
918	R:R:A645	R:R:F641	1.39	No	Yes	0	7	9
919	A:A:D295	A:A:K293	1.38	No	No	0	9	9
920	A:A:K32	A:A:Q35	1.36	No	No	0	4	3
921	A:A:E299	A:A:L296	1.33	No	No	0	6	6
922	B:B:H266	B:B:I269	1.33	No	No	0	4	4
923	R:R:F582	R:R:S579	1.32	No	No	0	1	3
924	R:R:H696	R:R:M699	1.31	No	Yes	0	5	7
925	R:R:D813	R:R:Q815	1.31	No	No	0	4	3
926	A:A:R42	A:A:T40	1.29	Yes	No	0	9	7
927	R:R:H691	R:R:L688	1.29	No	No	0	7	6
928	B:B:I123	B:B:R137	1.25	Yes	No	10	6	5
929	B:B:I171	B:B:R137	1.25	No	No	10	6	5
930	R:R:V755	R:R:W804	1.23	No	Yes	0	8	9
931	R:R:F759	R:R:L763	1.22	No	No	0	4	4
932	R:R:F759	R:R:L802	1.22	No	No	0	4	7
933	A:A:N279	A:A:R280	1.21	No	No	0	8	5
934	R:R:L769	R:R:R788	1.21	No	No	0	7	7
935	B:B:Q44	B:B:R42	1.17	No	No	0	4	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:I26	4.3225	4	8	9
2	A:A:Y37	5.326	5	1	4
3	A:A:H41	4.29	5	9	6
4	A:A:R42	5.916	5	1	9
5	A:A:L44	5.5225	4	1	9
6	A:A:S51	2.8625	4	0	9
7	A:A:I56	4.854	5	13	7
8	A:A:V217	3.3125	4	9	5
9	A:A:F219	4.72833	6	9	8
10	A:A:M221	4.27	4	0	8
11	A:A:F222	8.735	4	0	7
12	A:A:Q227	4.44429	7	1	9
13	A:A:K233	7.605	6	1	9
14	A:A:W234	5.37	4	1	9
15	A:A:F238	6.14	5	1	9
16	A:A:D240	4.7025	4	1	6
17	A:A:I245	3.52	4	0	7
18	A:A:V247	3.33	4	0	7
19	A:A:V248	4.54	4	0	7
20	A:A:D249	7.855	4	20	8
21	A:A:D252	5.6975	4	20	8
22	A:A:F273	4.565	6	5	9
23	A:A:W277	8.732	5	5	6
24	A:A:I288	4.975	4	0	9
25	A:A:F290	3.5	6	13	9
26	A:A:L291	4.33	4	5	8
27	A:A:N292	4.4675	4	13	9
28	A:A:Q294	5.99	5	5	6
29	A:A:E314	8.405	4	18	6
30	A:A:Y339	4.7575	4	5	3
31	A:A:F340	8.722	5	18	7
32	A:A:R342	7.19	4	5	4
33	A:A:E344	5.7425	4	18	5
34	A:A:F345	6.236	5	0	8
35	A:A:S349	4.12	5	5	7
36	A:A:C359	3.418	5	5	5
37	A:A:Y360	5.786	5	21	8
38	A:A:F363	6.892	5	5	5
39	A:A:T364	5.19833	6	13	9
40	A:A:F376	5.26875	8	9	8
41	A:A:I382	5.9025	4	21	6
42	A:A:I383	3.08	4	9	8
43	A:A:L388	2.8425	4	0	8
44	A:A:Y391	6.544	5	0	4
45	A:A:L393	3.875	4	22	8
46	B:B:M45	4.9725	4	0	4
47	B:B:R48	4.098	5	15	7
48	B:B:L51	7.1775	4	0	9
49	B:B:H54	7.05857	7	8	9
50	B:B:K57	7.88	5	1	9
51	B:B:Y59	8.84	4	1	8
52	B:B:W63	6.562	5	24	7
53	B:B:S72	5.3	4	8	9
54	B:B:Q75	7.30667	6	1	9
55	B:B:D76	6.076	5	0	9
56	B:B:L79	3.6675	4	11	7
57	B:B:I80	6.125	4	8	8
58	B:B:I81	5.654	5	11	7
59	B:B:W82	9.07	6	8	9
60	B:B:K89	6.152	5	8	9
61	B:B:L95	5.3725	4	11	8
62	B:B:W99	9.835	4	1	9
63	B:B:M101	3.9925	4	1	9
64	B:B:Y105	4.202	5	11	6
65	B:B:Y111	6.662	5	10	4
66	B:B:L117	3.482	5	1	9
67	B:B:I120	4.5475	4	25	6
68	B:B:I123	4.1825	4	10	6
69	B:B:E138	6.405	4	25	6
70	B:B:H142	7.172	5	12	9
71	B:B:Y145	4.7075	8	1	8
72	B:B:R150	4.0825	4	0	6
73	B:B:F151	5.42667	6	10	9
74	B:B:T159	5.4825	4	12	9
75	B:B:C166	4.235	4	7	8
76	B:B:L168	5.1025	4	7	6
77	B:B:W169	6.53571	7	12	8
78	B:B:D170	3.6025	4	26	9
79	B:B:F180	7.08333	6	7	7
80	B:B:H183	8.545	4	0	9
81	B:B:D186	7.756	5	1	9
82	B:B:M188	4.2525	4	1	8
83	B:B:L190	4.3775	4	0	5
84	B:B:R197	7.3425	4	16	5
85	B:B:L198	4.14	4	16	3
86	B:B:F199	7.008	5	7	9
87	B:B:V200	6.53	4	2	6
88	B:B:S201	4.6225	4	7	9
89	B:B:C204	6.3325	4	1	7
90	B:B:K209	10.332	5	7	6
91	B:B:L210	6.23	4	0	5
92	B:B:W211	9.43	5	7	8
93	B:B:D212	7.8525	4	16	9
94	B:B:Q220	7.008	5	2	7
95	B:B:F222	6.032	5	2	8
96	B:B:H225	7.39429	7	2	9
97	B:B:D228	6.3225	4	1	9
98	B:B:I229	4.365	4	2	7
99	B:B:I232	4.67143	7	2	8
100	B:B:F234	4.902	5	2	5
101	B:B:F235	7.524	5	2	6
102	B:B:P236	6.0025	4	2	7
103	B:B:N237	7.605	4	2	5
104	B:B:F241	5.57	6	2	6
105	B:B:T243	6.104	5	2	8
106	B:B:D247	7.6775	4	2	9
107	B:B:T249	5.485	4	2	6
108	B:B:R251	9.0675	4	2	8
109	B:B:F253	5.55	6	2	6
110	B:B:D254	5.1975	4	0	9
111	B:B:Y264	5.295	6	2	5
112	B:B:F278	3.35667	6	2	7
113	B:B:R283	5.59	4	27	9
114	B:B:Y289	6.05333	6	2	7
115	B:B:C294	4.215	4	6	5
116	B:B:V296	2.794	5	0	5
117	B:B:W297	8.685	4	2	8
118	B:B:L308	4.955	4	0	7
119	B:B:H311	6.12	4	6	9
120	B:B:R314	9.58	5	1	8
121	B:B:V327	4.7575	4	0	6
122	B:B:T329	5.76	4	6	8
123	B:B:W332	6.45667	6	1	9
124	B:B:L336	6.3875	4	8	7
125	B:B:K337	5.112	5	6	6
126	B:B:W339	5.966	5	6	9
127	G:G:Q18	5.872	5	7	9
128	G:G:Y40	10.25	4	2	6
129	R:R:F569	4.46833	6	4	9
130	R:R:S574	3.78	5	4	9
131	R:R:L593	4.3475	4	4	8
132	R:R:I597	2.9775	4	0	7
133	R:R:T619	6.5375	4	0	8
134	R:R:R624	4.7775	4	0	9
135	R:R:L634	5.7975	4	0	9
136	R:R:D638	4.2775	4	0	7
137	R:R:F641	3.1625	4	0	9
138	R:R:H665	4.915	4	14	9
139	R:R:F666	5.4525	4	0	7
140	R:R:Y668	5.235	6	4	8
141	R:R:L669	3.8375	4	14	9
142	R:R:L671	4.118	5	28	7
143	R:R:W674	6.40833	6	3	9
144	R:R:M675	4.09	4	28	9
145	R:R:L678	3.43	4	0	8
146	R:R:L681	5.7575	4	0	7
147	R:R:Y684	4.9	4	3	8
148	R:R:I686	2.938	5	23	7
149	R:R:F690	5.32333	6	9	8
150	R:R:M699	2.395	4	3	7
151	R:R:G702	3.1925	4	3	7
152	R:R:P710	4.722	5	14	9
153	R:R:Y727	7.5575	4	29	9
154	R:R:W734	7.5825	4	0	8
155	R:R:L735	7.0625	4	0	9
156	R:R:W737	6.422	5	0	6
157	R:R:P743	4.602	5	0	8
158	R:R:P798	2.7425	4	17	9
159	R:R:L799	4.21	4	0	6
160	R:R:L800	3.5525	4	0	9
161	R:R:W804	7.78571	7	4	9
162	R:R:T810	4.55833	6	4	7
163	R:R:H820	7.4275	4	4	8
164	R:R:F823	5.80333	6	4	9
165	R:R:N827	9.885	4	4	9
166	R:R:F829	5.262	5	17	7
167	R:R:F832	6.1575	4	17	5
168	R:R:F833	3.426	5	17	7
169	R:R:L845	4.4075	4	0	8
170	W:W:?1	6.62	9	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:I80	B:B:K78	14.1455	2.91	Yes	No	0	8	8
2	B:B:D76	B:B:K78	13.9507	8.3	Yes	No	0	9	8
3	A:A:L30	B:B:L55	45.5603	2.77	No	No	0	5	6
4	A:A:L30	B:B:K89	45.4359	2.82	No	Yes	8	5	9
5	A:A:K34	B:B:L55	53.7447	5.64	No	No	0	4	6
6	A:A:K34	A:A:R38	15.6615	7.43	No	No	3	4	4
7	A:A:K34	R:R:Q695	38.0346	5.42	No	No	3	4	6
8	A:A:Y37	B:B:D76	60.177	3.45	Yes	Yes	0	4	9
9	A:A:Y37	B:B:Q75	51.5076	3.38	Yes	Yes	1	4	9
10	A:A:R38	R:R:H692	15.6724	7.9	No	No	0	4	6
11	A:A:H41	R:R:H692	15.621	3.58	Yes	No	0	6	6
12	A:A:F219	A:A:H41	21.2761	4.53	Yes	Yes	9	8	6
13	A:A:F212	A:A:F219	20.4473	8.57	No	Yes	0	9	8
14	A:A:F212	A:A:M221	20.1926	2.49	No	Yes	0	9	8
15	A:A:I245	A:A:M221	19.6729	2.92	Yes	Yes	0	7	8
16	B:B:Q75	B:B:W99	41.3146	9.86	Yes	Yes	1	9	9
17	A:A:S51	A:A:V247	13.9646	3.23	Yes	Yes	0	9	7
18	A:A:F290	A:A:V247	14.2881	2.62	Yes	Yes	0	9	7
19	A:A:F290	A:A:I245	18.884	2.51	Yes	Yes	0	9	7
20	A:A:D249	A:A:S51	13.2834	2.94	Yes	Yes	0	8	9
21	B:B:L117	B:B:W99	35.872	3.42	Yes	Yes	1	9	9
22	B:B:L117	B:B:Y145	32.704	3.52	Yes	Yes	1	9	8
23	A:A:Q294	A:A:S250	11.2685	5.78	Yes	No	0	6	6
24	A:A:L297	A:A:S250	11.4045	6.01	No	No	0	8	6
25	A:A:L297	A:A:S251	11.676	4.5	No	No	0	8	9
26	A:A:L296	A:A:S251	11.9471	9.01	No	No	0	6	9
27	A:A:K293	A:A:L296	12.2177	4.23	No	No	0	9	6
28	A:A:D249	A:A:K293	12.6226	9.68	Yes	No	0	8	9
29	R:R:M699	R:R:Q695	38.0764	2.72	Yes	No	3	7	6
30	R:R:I625	R:R:M699	37.7424	2.92	No	Yes	3	7	7
31	R:R:I625	W:W:?1	37.7257	3.6	No	Yes	3	7	0
32	R:R:C626	W:W:?1	32.1054	2.67	No	Yes	0	7	0
33	R:R:C626	R:R:L678	31.6578	3.17	No	Yes	0	7	8
34	R:R:L678	R:R:L799	31.3673	4.15	Yes	Yes	0	8	6
35	B:B:I80	B:B:W82	14.1329	9.4	Yes	Yes	8	8	9
36	B:B:L51	B:B:W82	72.8696	15.94	Yes	Yes	0	9	9
37	B:B:I338	B:B:L51	86.6165	4.28	No	Yes	0	5	9
38	B:B:I338	B:B:R48	86.5367	6.26	No	Yes	15	5	7
39	B:B:N340	B:B:R48	86.5948	4.82	No	Yes	15	9	7
40	B:B:M45	B:B:N340	86.6619	2.8	Yes	No	0	4	9
41	B:B:M45	G:G:L50	84.5298	5.65	Yes	No	0	4	9
42	B:B:H54	B:B:L336	13.7242	3.86	Yes	Yes	8	9	7
43	B:B:H54	B:B:S72	13.7288	4.18	Yes	Yes	8	9	9
44	B:B:D76	B:B:S74	40.7527	4.42	Yes	No	0	9	9
45	B:B:M61	B:B:S72	14.3171	3.07	No	Yes	0	6	9
46	B:B:L70	B:B:M61	14.2664	5.65	No	No	0	5	6
47	B:B:S279	G:G:L50	85.5195	3	No	No	0	9	9
48	B:B:S279	G:G:D48	86.0689	4.42	No	No	0	9	9
49	B:B:S281	G:G:D48	100	10.31	No	No	0	9	9
50	B:B:G282	B:B:S281	99.9778	1.86	No	No	0	9	9
51	B:B:G282	B:B:P236	64.3019	4.06	No	Yes	2	9	7
52	B:B:F235	B:B:P236	32.4422	10.11	Yes	Yes	2	6	7
53	B:B:F235	B:B:N237	63.721	12.08	Yes	Yes	2	6	5
54	B:B:G238	B:B:N237	94.6871	3.39	No	Yes	2	7	5
55	B:B:F234	B:B:G238	94.1622	3.01	Yes	No	2	5	7
56	B:B:F234	B:B:V200	83.0453	10.49	Yes	Yes	2	5	6
57	B:B:L210	B:B:V200	65.9631	4.47	Yes	Yes	0	5	6
58	B:B:L210	B:B:Q220	64.9419	7.99	Yes	Yes	0	5	7
59	B:B:Q220	G:G:E22	64.5788	6.37	Yes	No	0	7	9
60	B:B:T221	G:G:E22	22.3584	8.47	No	No	0	7	9
61	B:B:K209	B:B:T221	22.0871	9.01	Yes	No	0	6	7
62	B:B:K209	B:B:W211	37.6102	15.08	Yes	Yes	7	6	8
63	B:B:F199	B:B:W211	44.8348	10.02	Yes	Yes	7	9	8
64	B:B:F199	B:B:L190	40.7248	6.09	Yes	Yes	0	9	5
65	B:B:L190	B:B:R150	38.28	2.43	Yes	Yes	0	5	6
66	B:B:H62	B:B:R150	35.7969	4.51	No	Yes	0	6	6
67	B:B:F278	B:B:G282	35.6534	3.01	Yes	No	2	7	9
68	B:B:F235	B:B:F278	33.179	6.43	Yes	Yes	2	6	7
69	B:B:P236	G:G:Y40	31.8237	6.95	Yes	Yes	2	7	6
70	B:B:N237	G:G:Y40	31.4695	8.14	Yes	Yes	2	5	6
71	G:G:E22	G:G:Q18	41.9593	2.55	No	Yes	0	9	9
72	B:B:K209	G:G:Q18	22.1258	4.07	Yes	Yes	7	6	9
73	B:B:C218	G:G:Q18	19.0831	9.16	No	Yes	7	5	9
74	B:B:C218	B:B:W211	18.8107	2.61	No	Yes	7	5	8
75	B:B:L70	B:B:W63	14.152	9.11	No	Yes	24	5	7
76	B:B:T321	B:B:W63	14.1636	10.92	No	Yes	0	7	7
77	B:B:H62	B:B:Y105	34.967	2.18	No	Yes	0	6	6
78	B:B:V71	B:B:Y105	23.3328	7.57	No	Yes	11	8	6
79	B:B:L79	B:B:V71	21.6683	2.98	Yes	No	11	7	8
80	B:B:L79	B:B:L95	16.6836	5.54	Yes	Yes	11	7	8
81	B:B:L95	B:B:Y124	12.5182	8.21	Yes	No	0	8	6
82	B:B:G162	B:B:Y145	24.7792	2.9	No	Yes	1	9	8
83	B:B:G162	B:B:S161	24.5077	3.71	No	No	0	9	9
84	B:B:H142	B:B:S161	22.5592	16.74	Yes	No	0	9	9
85	B:B:H142	B:B:T159	10.1468	6.85	Yes	Yes	12	9	9
86	B:B:I157	B:B:W169	13.1107	2.35	No	Yes	0	7	8
87	B:B:A167	B:B:H142	10.1471	4.39	No	Yes	12	4	9
88	B:B:F151	B:B:I157	11.1472	12.56	Yes	No	0	9	7
89	B:B:D323	B:B:T321	14.1039	7.23	No	No	0	7	7
90	B:B:D323	B:B:M325	14.0645	5.54	No	No	0	7	5
91	B:B:M325	G:G:P49	14.0451	6.71	No	No	0	5	7
92	R:R:I630	R:R:L799	23.7507	2.85	No	Yes	0	8	6
93	R:R:I630	R:R:L671	23.4295	2.85	No	Yes	28	8	7
94	R:R:F672	R:R:L671	12.411	4.87	No	Yes	0	9	7
95	R:R:F672	R:R:W804	12.1922	19.04	No	Yes	0	9	9
96	R:R:L800	R:R:N758	12.3588	8.24	Yes	No	0	9	9
97	R:R:I754	R:R:N758	12.0266	4.25	No	No	0	9	9
98	R:R:F673	R:R:I754	11.3613	3.77	No	No	0	8	9
99	R:R:F673	R:R:P710	10.7011	10.11	No	Yes	14	8	9
100	B:B:K89	B:B:W82	45.5892	13.92	Yes	Yes	8	9	9
101	B:B:H54	B:B:W82	13.6988	7.41	Yes	Yes	8	9	9
102	B:B:L336	B:B:L51	13.9027	5.54	Yes	Yes	0	7	9
103	B:B:H54	B:B:S74	40.9146	12.55	Yes	No	0	9	9
104	G:G:D48	G:G:P49	14.0259	3.22	No	No	0	9	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:Y391	R:R:L678	4.69	0	Yes	Yes	4	8	2	2
A:A:Y391	R:R:L681	4.69	0	Yes	Yes	4	7	2	1
R:R:H621	R:R:I625	3.98	3	No	No	6	7	2	1
R:R:H621	R:R:M699	2.63	3	No	Yes	6	7	2	2
R:R:L681	R:R:T622	2.95	0	Yes	No	7	7	1	2
R:R:M698	R:R:T622	3.01	3	No	No	8	7	1	2
R:R:I625	R:R:M699	2.92	3	No	Yes	7	7	1	2
R:R:I625	W:W:?1	3.6	3	No	Yes	7	0	1	0
R:R:C626	R:R:W674	2.61	0	No	Yes	7	9	1	2
R:R:C626	R:R:L678	3.17	0	No	Yes	7	8	1	2
R:R:C626	W:W:?1	2.67	0	No	Yes	7	0	1	0
R:R:G702	R:R:W674	2.81	3	Yes	Yes	7	9	1	2
R:R:G702	R:R:M677	5.24	3	Yes	No	7	6	1	1
R:R:L705	R:R:M677	5.65	0	No	No	6	6	2	1
R:R:M677	W:W:?1	9.52	3	No	Yes	6	0	1	0
R:R:I680	W:W:?1	15.62	0	No	Yes	8	0	1	0
R:R:L681	R:R:R685	6.07	0	Yes	No	7	8	1	2
R:R:L681	W:W:?1	9.32	0	Yes	Yes	7	0	1	0
R:R:L688	R:R:Y684	5.86	3	No	Yes	6	8	1	1
R:R:M693	R:R:Y684	5.99	0	No	Yes	5	8	2	1
R:R:M698	R:R:Y684	4.79	3	No	Yes	8	8	1	1
R:R:Y684	W:W:?1	2.96	3	Yes	Yes	8	0	1	0
R:R:L688	W:W:?1	3.49	3	No	Yes	6	0	1	0
R:R:M698	W:W:?1	9.52	3	No	Yes	8	0	1	0
R:R:G702	W:W:?1	2.88	3	Yes	Yes	7	0	1	0
R:R:G702	R:R:V701	1.84	3	Yes	No	7	6	1	2
R:R:H691	R:R:L688	1.29	0	No	No	7	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
69.23	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/&β;1/&γ;2
58.33	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/&β;1/&γ;2
40.00	Single	5XSZ	Glyceryl Mono-oleate	5XSZ-LPA₆-Glyceryl Mono-oleate
40.00	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2
28.57	Single	5KW2	PubChem 133053953	5KW2-FFA1 (GPR40)-PubChem 133053953
25.00	Consensus	adgrf1_on_allo	Other Ligand	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2 8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
20.00	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
18.75	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
15.38	Single	8U4P	Cholesterol	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
13.33	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
13.33	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
13.33	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
13.33	Single	8U4Q	Cholesterol	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
12.50	Single	7LJC	Mevidalen	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
12.50	Consensus	d1_on_allo	Other Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
11.11	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
11.11	Consensus	c5a1_off_ortoallo	Other Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
9.52	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
8.33	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
8.00	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
8.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
7.69	Single	8U4N	Cholesterol	8U4N-CXCR4-Cholesterol-Gi1/&β;1/&γ;2
7.14	Single	6KQI	ORG27569	6KQI-CB₁-PubMed 104895-ORG27569
7.14	Consensus	cb1_off_allo	Other Ligand	6KQI-CB₁-PubMed 104895-ORG27569
6.67	Single	6OBA	GTPL11074	6OBA-β₂-(S)-Alprenolol-GTPL11074
6.67	Single	8U4O	Cholesterol	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
6.67	Single	8U4R	Cholesterol	8U4R-CXCR4-REGN7663-Fab-Cholesterol
6.67	Consensus	beta2_off_allo	Other Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
5.88	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
5.88	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/&β;1/&γ;2
5.56	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
5.56	Single	8IYX	YL-365	8IYX-GPR34-YL-365
4.35	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

PDB Summary
PDB	8G2Y
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRF1
Species	Homo sapiens
Ligand	-
Other Ligand(s)	LPC
Protein Partners	chim(Gs-CtGq)/Beta1/Gamma2
PDB Resolution	3.44
Date	2023-05-10
D.O.I.	10.1038/s41467-023-38083-7

Net Summary
I_min	2.49
Number of Linked Nodes	729
Number of Links	935
Number of Hubs	170
Number of Links mediated by Hubs	604
Number of Communities	30
Number of Nodes involved in Communities	248
Number of Links involved in Communities	359

Path Summary
Number Of Nodes in MetaPath	105
Number Of Links MetaPath	104
Number of Shortest Paths	2147838
Length Of Smallest Path	3
Average Path Length	35.2102
Length of Longest Path	66
Minimum Path Strength	1.22
Average Path Strength	5.79025
Maximum Path Strength	21.4
Minimum Path Correlation	0.7
Average Path Correlation	0.982568
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.32558
Average % Of Corr. Nodes	37.7136
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	56.2292
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	LPC
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	LPC
Name	[1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE
Synonyms
Identifier	2-[hydroxy-[(2R)-2-hydroxy-3-tetradecanoyloxy-propoxy]phosphoryl]oxyethyl-trimethyl-azanium
Formula	C22 H47 N O7 P
Molecular Weight	468.585
SMILES	CCCCCCCCCCCCCC(=O)OC[C@H](CO[P@](=O)(O)OCC[N+](C)(C)C)O
PubChem	444675
Formal Charge	1
Total Atoms	78
Total Chiral Atoms	2
Total Bonds	77
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8G2Y_Chain_A K I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I I F E T K F Q V D K V N F H M F D V G G Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N L F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A Y F P E F A R Y T T P D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N A R R I F N D C K D I I L Q M N L R E Y N L V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8G2Y_Chain_B G R I Q M R T R R T L R G H L A K I Y A M H W G L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8G2Y_Chain_G R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q5T601
Sequence	>8G2Y_Chain_R T S F S I L M S P F V P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L V F H H M A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q Y K R K D V C W L N W S N G S K P L L A F V V P A L A I V A V N F V V V L L V L T K L W T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S Q N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L R Q L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This network is also present in following consensuses:
	Id	Components
	adgrf1_on_allo	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2 8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7WU3	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gs/&β;1/&γ;2	3.1	2022-04-27	10.1038/s41586-022-04580-w
	7WU4	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/&β;1/&γ;2	3.4	2022-04-27	10.1038/s41586-022-04580-w
	7WU5	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/&β;1/&γ;2	3	2022-04-27	10.1038/s41586-022-04580-w
	7WXU	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.85	2022-09-28	10.1038/s41467-022-33173-4
	7WXW	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.84	2022-09-28	10.1038/s41467-022-33173-4
	7WY0	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1L-G13)/&β;1/&γ;2	2.83	2022-09-28	10.1038/s41467-022-33173-4
	7WZ7	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-G12)/&β;1/&γ;2	2.83	2022-09-28	10.1038/s41467-022-33173-4
	7X2V	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.09	2022-09-28	10.1038/s41467-022-33173-4
	8G2Y	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC	chim(Gs-CtGq)/&β;1/&γ;2	3.44	2023-05-10	10.1038/s41467-023-38083-7

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