psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D9	A:A:L5	6.79	No	Yes	0	4	2
2	A:A:D9	A:A:S6	8.83	No	No	0	4	7
3	A:A:K17	A:A:V13	4.55	No	No	0	4	3
4	A:A:V13	B:B:N88	5.91	No	No	0	3	7
5	A:A:I19	A:A:R15	5.01	No	No	0	9	5
6	A:A:D20	A:A:S16	4.42	No	No	8	6	7
7	A:A:S16	B:B:N88	8.94	No	No	0	7	7
8	A:A:S16	B:B:K89	3.06	No	Yes	8	7	9
9	A:A:I19	B:B:K89	5.82	No	Yes	0	9	9
10	A:A:D20	B:B:K89	11.06	No	Yes	8	6	9
11	A:A:R21	A:A:R24	3.2	No	No	0	4	3
12	A:A:E25	A:A:R21	3.49	No	No	0	4	4
13	A:A:L23	B:B:K78	4.23	No	No	0	6	8
14	A:A:R32	R:R:T144	3.88	No	No	0	4	6
15	A:A:E33	A:A:H195	6.15	No	No	0	6	4
16	A:A:E33	A:A:K197	9.45	No	Yes	0	6	6
17	A:A:L194	A:A:V34	4.47	Yes	Yes	9	4	5
18	A:A:F196	A:A:V34	5.24	Yes	Yes	9	7	5
19	A:A:T219	A:A:V34	6.35	No	Yes	0	7	5
20	A:A:V339	A:A:V34	4.81	No	Yes	9	8	5
21	A:A:K197	A:A:K35	4.31	Yes	No	1	6	9
22	A:A:F199	A:A:K35	7.44	Yes	No	1	5	9
23	A:A:K35	B:B:W99	4.64	No	Yes	1	9	9
24	A:A:L36	A:A:M198	7.07	No	Yes	0	7	7
25	A:A:L37	A:A:L39	6.92	No	No	0	9	9
26	A:A:F215	A:A:L37	9.74	Yes	No	0	9	9
27	A:A:K46	A:A:L38	9.87	Yes	No	0	9	8
28	A:A:L38	A:A:M198	7.07	No	Yes	0	8	7
29	A:A:D200	A:A:L38	4.07	No	No	0	9	8
30	A:A:I253	A:A:L39	4.28	No	No	0	8	9
31	A:A:G40	A:A:K46	5.23	No	Yes	0	9	9
32	A:A:A41	A:A:E43	4.53	No	No	0	7	9
33	A:A:A41	A:A:S44	3.42	No	No	0	7	9
34	A:A:E43	A:A:R242	9.3	No	No	0	9	9
35	A:A:K46	A:A:S44	6.12	Yes	No	20	9	9
36	A:A:C224	A:A:S44	3.44	No	No	20	7	9
37	A:A:G45	A:A:N269	3.39	No	Yes	0	9	9
38	A:A:C224	A:A:K46	3.23	No	Yes	20	7	9
39	A:A:I49	A:A:Q52	6.86	No	No	0	7	9
40	A:A:I49	A:A:M53	4.37	No	No	0	7	8
41	A:A:I49	A:A:N269	8.5	No	Yes	0	7	9
42	A:A:D328	A:A:Q52	9.14	No	No	0	9	9
43	A:A:D328	A:A:I56	8.4	No	No	0	9	7
44	A:A:F189	A:A:H57	4.53	No	No	0	9	8
45	A:A:H57	A:A:T190	4.11	No	No	0	8	3
46	A:A:T182	B:B:N119	8.77	No	Yes	0	7	9
47	A:A:G183	B:B:N119	6.79	No	Yes	0	9	9
48	A:A:I184	A:A:V201	4.61	No	No	1	9	9
49	A:A:I184	B:B:W99	4.7	No	Yes	1	9	9
50	A:A:I184	B:B:L117	7.14	No	No	1	9	9
51	A:A:E186	A:A:H188	13.54	No	No	1	9	3
52	A:A:E186	A:A:K197	4.05	No	Yes	1	9	6
53	A:A:E186	A:A:F199	5.83	No	Yes	1	9	5
54	A:A:H188	A:A:K197	6.55	No	Yes	1	3	6
55	A:A:F189	A:A:F196	16.08	No	Yes	0	9	7
56	A:A:F189	A:A:M198	3.73	No	Yes	0	9	7
57	A:A:H195	A:A:T190	8.21	No	No	0	4	3
58	A:A:F191	A:A:K192	13.65	Yes	No	9	5	4
59	A:A:F191	A:A:V332	10.49	Yes	No	0	5	7
60	A:A:F191	A:A:Q333	3.51	Yes	No	0	5	5
61	A:A:F191	A:A:F336	6.43	Yes	No	9	5	8
62	A:A:F336	A:A:K192	7.44	No	No	9	8	4
63	A:A:D193	R:R:N141	4.04	No	No	0	3	5
64	A:A:F196	A:A:L194	9.74	Yes	Yes	9	7	4
65	A:A:F336	A:A:L194	6.09	No	Yes	9	8	4
66	A:A:L194	R:R:V137	5.96	Yes	No	0	4	6
67	A:A:F196	A:A:V339	6.55	Yes	No	9	7	8
68	A:A:F199	A:A:K197	7.44	Yes	Yes	1	5	6
69	A:A:F199	B:B:W99	14.03	Yes	Yes	1	5	9
70	A:A:V201	A:A:W211	7.36	No	Yes	1	9	9
71	A:A:F215	A:A:V201	3.93	Yes	No	1	9	9
72	A:A:Q204	A:A:S206	8.66	Yes	No	0	9	8
73	A:A:Q204	A:A:W211	4.38	Yes	Yes	1	9	9
74	A:A:Q204	B:B:N119	3.96	Yes	Yes	1	9	9
75	A:A:Q204	B:B:G144	4.93	Yes	No	1	9	8
76	A:A:Q204	B:B:Y145	5.64	Yes	Yes	1	9	8
77	A:A:E207	A:A:K209	17.55	No	No	0	9	8
78	A:A:L249	A:A:R208	4.86	No	No	0	9	9
79	A:A:R208	A:A:S252	3.95	No	No	0	9	7
80	A:A:K210	B:B:M188	5.76	No	No	0	9	8
81	A:A:K210	B:B:N230	11.19	No	No	0	9	9
82	A:A:F215	A:A:W211	5.01	Yes	Yes	1	9	9
83	A:A:W211	B:B:Y145	6.75	Yes	Yes	1	9	8
84	A:A:F259	A:A:I212	5.02	Yes	No	0	9	8
85	A:A:C214	A:A:H213	4.42	No	Yes	1	7	8
86	A:A:H213	A:A:W258	8.46	Yes	Yes	1	8	5
87	A:A:H213	B:B:Y59	6.53	Yes	Yes	1	8	8
88	A:A:H213	B:B:W332	10.58	Yes	Yes	1	8	9
89	A:A:C214	B:B:Y59	5.38	No	Yes	1	7	8
90	A:A:C214	B:B:Q75	3.05	No	No	1	7	9
91	A:A:F215	B:B:W99	15.03	Yes	Yes	1	9	9
92	A:A:E216	A:A:W258	10.9	No	Yes	0	7	5
93	A:A:E216	B:B:K57	8.1	No	No	0	7	9
94	A:A:T262	A:A:V218	3.17	No	No	0	7	9
95	A:A:F259	A:A:I221	8.79	Yes	No	6	9	8
96	A:A:I221	A:A:T262	3.04	No	No	6	8	7
97	A:A:I221	A:A:I264	4.42	No	Yes	6	8	6
98	A:A:I222	A:A:I265	5.89	No	Yes	16	7	8
99	A:A:F267	A:A:I222	6.28	Yes	No	16	9	7
100	A:A:F223	A:A:F250	13.93	No	No	0	9	9
101	A:A:F223	A:A:L266	4.87	No	Yes	0	9	9
102	A:A:C224	A:A:N269	3.15	No	Yes	0	7	9
103	A:A:S246	A:A:V225	3.23	No	No	0	9	7
104	A:A:F307	A:A:V225	3.93	No	No	0	8	7
105	A:A:A226	A:A:D229	6.18	No	Yes	0	8	8
106	A:A:L227	A:A:L268	6.92	No	No	0	7	8
107	A:A:F274	A:A:L227	9.74	Yes	No	0	9	7
108	A:A:I303	A:A:L227	4.28	No	No	0	7	7
109	A:A:D229	A:A:S228	4.42	Yes	No	0	8	9
110	A:A:K270	A:A:S228	6.12	No	No	0	9	9
111	A:A:L273	A:A:S228	6.01	No	No	0	6	9
112	A:A:D229	A:A:L232	4.07	Yes	No	0	8	8
113	A:A:D229	A:A:R242	4.76	Yes	No	0	8	9
114	A:A:D231	A:A:Y230	11.49	Yes	Yes	17	9	8
115	A:A:F274	A:A:Y230	8.25	Yes	Yes	0	9	8
116	A:A:K277	A:A:Y230	11.94	No	Yes	17	9	8
117	A:A:S281	A:A:Y230	3.82	No	Yes	17	7	8
118	A:A:L283	A:A:Y230	4.69	No	Yes	0	7	8
119	A:A:C286	A:A:Y230	4.03	No	Yes	0	6	8
120	A:A:D231	A:A:L232	5.43	Yes	No	0	9	8
121	A:A:D231	A:A:K277	12.44	Yes	No	17	9	9
122	A:A:D231	A:A:S281	5.89	Yes	No	17	9	7
123	A:A:M240	A:A:V233	3.04	No	No	0	6	5
124	A:A:L234	A:A:R242	9.72	No	No	0	8	9
125	A:A:E239	A:A:H244	4.92	No	No	0	4	4
126	A:A:M243	A:A:N241	5.61	No	No	0	8	9
127	A:A:H244	A:A:N241	3.83	No	No	0	4	9
128	A:A:C286	A:A:M243	3.24	No	No	0	6	8
129	A:A:M247	A:A:Q306	5.44	No	No	0	6	5
130	A:A:F307	A:A:M247	4.98	No	No	0	8	6
131	A:A:L310	A:A:M247	7.07	No	No	0	4	6
132	A:A:I253	A:A:L249	4.28	No	No	0	8	9
133	A:A:F250	A:A:I264	7.54	No	Yes	0	9	6
134	A:A:F250	A:A:I319	5.02	No	No	0	9	5
135	A:A:D251	A:A:N255	9.42	No	No	6	5	8
136	A:A:D251	A:A:K312	5.53	No	No	6	5	5
137	A:A:C254	A:A:N255	3.15	Yes	No	6	5	8
138	A:A:C254	A:A:I264	3.27	Yes	Yes	6	5	6
139	A:A:C254	A:A:N311	6.3	Yes	Yes	6	5	8
140	A:A:C254	A:A:K317	4.85	Yes	No	6	5	7
141	A:A:K312	A:A:N255	15.39	No	No	6	5	8
142	A:A:N256	A:A:W258	7.91	No	Yes	0	8	5
143	A:A:F259	A:A:N256	7.25	Yes	No	0	9	8
144	A:A:K257	A:A:W258	17.4	No	Yes	0	4	5
145	A:A:W258	B:B:R314	8	Yes	No	1	5	8
146	A:A:W258	B:B:W332	7.5	Yes	Yes	1	5	9
147	A:A:F259	A:A:T262	5.19	Yes	No	6	9	7
148	A:A:R313	A:A:T260	3.88	No	No	0	4	3
149	A:A:D261	A:A:T316	7.23	No	No	0	4	3
150	A:A:S263	A:A:V342	3.23	No	No	18	7	7
151	A:A:K345	A:A:S263	4.59	Yes	No	18	5	7
152	A:A:I264	A:A:K317	5.82	Yes	No	6	6	7
153	A:A:F267	A:A:I265	6.28	Yes	Yes	16	9	8
154	A:A:I265	A:A:Y320	3.63	Yes	Yes	0	8	7
155	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
156	A:A:L266	A:A:L268	5.54	Yes	No	0	9	8
157	A:A:F307	A:A:L266	3.65	No	Yes	0	8	9
158	A:A:L266	A:A:T321	4.42	Yes	No	0	9	5
159	A:A:F267	A:A:H322	4.53	Yes	Yes	16	9	9
160	A:A:F267	A:A:T324	3.89	Yes	No	0	9	9
161	A:A:F267	A:A:F334	3.22	Yes	No	16	9	3
162	A:A:F323	A:A:L268	6.09	No	No	0	4	8
163	A:A:N269	A:A:T324	8.77	Yes	No	0	9	9
164	A:A:E275	A:A:K271	5.4	No	No	21	5	5
165	A:A:K271	A:A:Y296	3.58	No	Yes	21	5	4
166	A:A:C325	A:A:K271	6.47	No	No	0	7	5
167	A:A:D272	A:A:L273	8.14	No	No	0	9	6
168	A:A:F274	A:A:Y296	5.16	Yes	Yes	0	9	4
169	A:A:E275	A:A:Y296	24.69	No	Yes	21	5	4
170	A:A:I278	A:A:N294	5.66	No	No	0	6	3
171	A:A:P282	A:A:S281	3.56	No	No	0	5	7
172	A:A:P282	A:A:T284	3.5	No	No	0	5	4
173	A:A:L283	A:A:Y287	4.69	No	Yes	0	7	7
174	A:A:C286	A:A:Y287	8.06	No	Yes	0	6	7
175	A:A:E289	A:A:Y287	7.86	No	Yes	22	6	7
176	A:A:Y287	A:A:Y302	4.96	Yes	No	22	7	6
177	A:A:I303	A:A:Y287	4.84	No	Yes	0	7	7
178	A:A:E289	A:A:P288	4.72	No	No	0	6	5
179	A:A:E289	A:A:Y302	5.61	No	No	22	6	6
180	A:A:G292	A:A:Y290	5.79	No	No	0	7	7
181	A:A:Y290	A:A:Y302	10.92	No	No	0	7	6
182	A:A:S293	A:A:T295	4.8	No	No	0	3	5
183	A:A:A300	A:A:Y296	4	No	Yes	0	5	4
184	A:A:Q304	A:A:T321	9.92	No	No	0	5	5
185	A:A:F323	A:A:Q304	3.51	No	No	0	4	5
186	A:A:D309	A:A:E308	6.5	No	No	0	4	3
187	A:A:E308	A:A:K314	8.1	No	No	0	3	3
188	A:A:K314	A:A:N311	8.39	No	Yes	0	3	8
189	A:A:K317	A:A:N311	6.99	No	Yes	6	7	8
190	A:A:I319	A:A:N311	5.66	No	Yes	0	5	8
191	A:A:R313	A:A:T316	5.17	No	No	0	4	3
192	A:A:D315	A:A:T316	7.23	No	No	0	3	3
193	A:A:E318	A:A:Y320	15.71	No	Yes	0	4	7
194	A:A:E318	R:R:R238	5.82	No	Yes	23	4	3
195	A:A:E318	R:R:R239	3.49	No	No	23	4	4
196	A:A:D341	A:A:Y320	5.75	No	Yes	0	8	7
197	A:A:H322	A:A:K330	7.86	Yes	No	0	9	4
198	A:A:H322	A:A:N331	6.38	Yes	No	0	9	8
199	A:A:F334	A:A:H322	16.97	No	Yes	16	3	9
200	A:A:N331	A:A:T324	13.16	No	No	0	8	9
201	A:A:C325	A:A:S326	3.44	No	No	0	7	9
202	A:A:D328	A:A:T329	4.34	No	No	0	9	9
203	A:A:D337	A:A:Q333	11.75	No	No	0	4	5
204	A:A:I343	A:A:V339	3.07	No	No	0	7	8
205	A:A:T340	R:R:R236	3.88	No	No	0	6	5
206	A:A:D341	R:R:R236	9.53	No	No	0	8	5
207	A:A:D341	R:R:R238	9.53	No	Yes	0	8	3
208	A:A:K345	A:A:V342	7.59	Yes	No	18	5	7
209	A:A:N346	A:A:V342	4.43	No	No	18	4	7
210	A:A:I343	A:A:N347	4.25	No	No	0	7	8
211	A:A:I343	R:R:Q140	5.49	No	No	0	7	4
212	A:A:I344	R:R:P136	8.47	No	No	0	6	8
213	A:A:K345	A:A:N346	6.99	Yes	No	18	5	4
214	A:A:K345	A:A:K349	7.18	Yes	No	0	5	5
215	A:A:N347	R:R:Q132	5.28	No	Yes	0	8	7
216	A:A:F354	A:A:L348	13.4	No	No	0	5	9
217	A:A:C351	A:A:L353	4.76	No	No	0	4	7
218	A:A:L353	R:R:F244	8.53	No	Yes	0	7	7
219	A:A:F354	R:R:P241	10.11	No	No	0	5	6
220	A:A:F354	R:R:F244	3.22	No	Yes	0	5	7
221	B:B:D5	B:B:Q9	5.22	No	No	0	1	3
222	B:B:L7	G:G:A12	4.73	No	No	0	8	5
223	B:B:E10	G:G:V16	12.84	No	No	0	8	7
224	B:B:E12	B:B:N16	9.2	No	No	0	4	1
225	B:B:Q13	B:B:Q17	5.12	No	No	0	1	4
226	B:B:L14	G:G:L19	8.3	Yes	No	0	8	9
227	B:B:K15	G:G:L19	7.05	No	No	0	6	9
228	B:B:I18	G:G:A23	3.25	No	No	0	7	8
229	B:B:A21	G:G:R27	5.53	No	No	0	4	8
230	B:B:D258	B:B:R22	10.72	No	No	0	7	6
231	B:B:Q259	B:B:R22	4.67	No	No	0	6	6
232	B:B:C25	G:G:R27	4.18	No	No	0	3	8
233	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
234	B:B:A28	B:B:D27	3.09	No	No	0	4	8
235	B:B:D27	G:G:K29	17.97	No	No	0	8	4
236	B:B:D27	G:G:S31	5.89	No	No	0	8	9
237	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
238	B:B:L30	B:B:M262	7.07	No	No	0	5	4
239	B:B:I33	G:G:S31	3.1	No	No	0	3	9
240	B:B:I33	G:G:M38	4.37	No	Yes	0	3	4
241	B:B:L300	B:B:T34	5.9	Yes	No	12	6	5
242	B:B:K301	B:B:T34	3	Yes	No	0	5	5
243	B:B:T34	G:G:M38	4.52	No	Yes	12	5	4
244	B:B:I37	G:G:M38	4.37	No	Yes	0	2	4
245	B:B:K301	B:B:P39	3.35	Yes	No	0	5	1
246	B:B:I43	B:B:V40	3.07	No	Yes	0	3	3
247	B:B:R283	B:B:V40	5.23	No	Yes	12	9	3
248	B:B:D298	B:B:V40	4.38	Yes	Yes	12	9	3
249	B:B:Q44	B:B:R42	18.69	No	No	0	4	2
250	B:B:G306	B:B:R42	6	No	No	0	4	2
251	B:B:A305	B:B:I43	3.25	No	No	0	4	3
252	B:B:L308	B:B:M45	4.24	No	No	0	7	4
253	B:B:K337	B:B:T47	4.5	Yes	No	5	6	3
254	B:B:T47	B:B:W339	9.7	No	Yes	5	3	9
255	B:B:R48	B:B:R49	3.2	No	No	0	7	7
256	B:B:R49	G:G:F61	7.48	No	Yes	0	7	8
257	B:B:R49	G:G:K64	3.71	No	No	0	7	8
258	B:B:R52	B:B:T50	11.64	No	No	0	7	3
259	B:B:T50	R:R:R60	3.88	No	Yes	0	3	5
260	B:B:L51	B:B:W82	15.94	No	Yes	0	9	9
261	B:B:L336	B:B:L51	6.92	No	No	0	7	9
262	B:B:F335	B:B:R52	5.34	Yes	No	0	4	7
263	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
264	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
265	B:B:H54	B:B:S72	5.58	Yes	No	8	9	9
266	B:B:H54	B:B:S74	8.37	Yes	No	0	9	9
267	B:B:H54	B:B:I80	11.93	Yes	No	8	9	8
268	B:B:H54	B:B:W82	10.58	Yes	Yes	8	9	9
269	B:B:L55	R:R:R62	3.64	No	No	0	6	5
270	B:B:A56	B:B:D76	3.09	No	No	0	7	9
271	B:B:K57	B:B:Y59	5.97	No	Yes	1	9	8
272	B:B:K57	B:B:W332	13.92	No	Yes	1	9	9
273	B:B:I58	B:B:S316	3.1	No	No	0	9	9
274	B:B:Q75	B:B:Y59	12.4	No	Yes	1	9	8
275	B:B:W332	B:B:Y59	22.19	Yes	Yes	1	9	8
276	B:B:A60	B:B:C103	3.61	No	No	0	7	8
277	B:B:M61	B:B:W63	3.49	No	Yes	0	6	7
278	B:B:C317	B:B:M61	4.86	No	No	0	7	6
279	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
280	B:B:L70	B:B:W63	18.22	No	Yes	0	5	7
281	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
282	B:B:T321	B:B:W63	9.7	No	Yes	0	7	7
283	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
284	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
285	B:B:D66	B:B:R68	3.57	No	No	0	8	5
286	B:B:D66	B:B:L69	9.5	No	No	0	8	5
287	B:B:S67	B:B:T321	3.2	No	No	4	5	7
288	B:B:D322	B:B:S67	4.42	No	No	0	1	5
289	B:B:D323	B:B:S67	11.78	No	No	4	7	5
290	B:B:D83	B:B:R68	20.25	No	No	0	8	5
291	B:B:R68	B:B:Y85	21.61	No	Yes	0	5	4
292	B:B:D83	B:B:L69	4.07	No	No	0	8	5
293	B:B:I81	B:B:V71	3.07	No	No	0	7	8
294	B:B:V71	B:B:Y105	5.05	No	Yes	0	8	6
295	B:B:S72	B:B:W82	6.18	No	Yes	8	9	9
296	B:B:A73	B:B:V100	3.39	No	No	0	9	9
297	B:B:A73	B:B:C103	3.61	No	No	0	9	8
298	B:B:D76	B:B:S74	10.31	No	No	0	9	9
299	B:B:Q75	B:B:W99	5.48	No	Yes	1	9	9
300	B:B:D76	B:B:K78	8.3	No	No	0	9	8
301	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
302	B:B:K78	B:B:P94	3.35	No	No	0	8	5
303	B:B:L79	B:B:L95	11.07	No	Yes	13	7	8
304	B:B:C114	B:B:L79	3.17	No	No	13	8	7
305	B:B:I80	B:B:W82	16.44	No	Yes	8	8	9
306	B:B:I80	B:B:K89	8.72	No	Yes	8	8	9
307	B:B:I81	B:B:V90	4.61	No	No	0	7	5
308	B:B:I81	B:B:L126	4.28	No	No	0	7	5
309	B:B:K89	B:B:W82	11.6	Yes	Yes	8	9	9
310	B:B:D83	B:B:T86	7.23	No	No	0	8	6
311	B:B:S84	B:B:Y85	6.36	No	Yes	4	5	4
312	B:B:S84	G:G:F61	5.28	No	Yes	4	5	8
313	B:B:Y85	G:G:P60	12.52	Yes	Yes	4	4	9
314	B:B:Y85	G:G:F61	7.22	Yes	Yes	4	4	8
315	B:B:N88	B:B:T86	10.24	No	No	0	7	6
316	B:B:H91	B:B:V90	4.15	No	No	0	5	5
317	B:B:H91	B:B:V133	5.54	No	Yes	0	5	4
318	B:B:I93	B:B:P94	3.39	No	No	0	7	5
319	B:B:I93	B:B:Y124	10.88	No	Yes	13	7	6
320	B:B:I93	B:B:V133	7.68	No	Yes	13	7	4
321	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
322	B:B:C114	B:B:L95	3.17	No	Yes	13	8	8
323	B:B:L95	B:B:Y124	3.52	Yes	Yes	13	8	6
324	B:B:E138	B:B:R96	4.65	No	No	0	6	6
325	B:B:D118	B:B:S97	4.42	No	No	0	9	8
326	B:B:S98	B:B:W99	4.94	No	Yes	0	8	9
327	B:B:L117	B:B:W99	6.83	No	Yes	1	9	9
328	B:B:G116	B:B:M101	3.49	No	No	0	9	9
329	B:B:M101	B:B:Y145	3.59	No	Yes	0	9	8
330	B:B:C149	B:B:T102	5.07	Yes	No	0	8	8
331	B:B:G109	B:B:Y105	7.24	No	Yes	0	5	6
332	B:B:A106	B:B:F151	9.71	No	Yes	0	6	9
333	B:B:N110	B:B:S108	10.43	No	No	0	4	6
334	B:B:K127	B:B:N110	11.19	No	No	0	4	4
335	B:B:N125	B:B:Y111	17.44	No	No	0	4	4
336	B:B:S136	B:B:Y111	3.82	No	No	0	4	4
337	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
338	B:B:G115	B:B:L146	3.42	No	No	0	9	7
339	B:B:L117	B:B:Y145	3.52	No	Yes	1	9	8
340	B:B:G144	B:B:N119	5.09	No	Yes	1	8	9
341	B:B:A140	B:B:I120	4.87	No	No	0	5	6
342	B:B:C121	B:B:L139	4.76	No	No	0	8	9
343	B:B:C121	B:B:T159	3.38	No	Yes	0	8	9
344	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
345	B:B:I123	B:B:S136	6.19	No	No	0	6	4
346	B:B:V133	B:B:Y124	3.79	Yes	Yes	13	4	6
347	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
348	B:B:N125	B:B:T128	5.85	No	No	0	4	3
349	B:B:L126	B:B:V133	4.47	No	Yes	0	5	4
350	B:B:E130	B:B:N132	18.4	No	No	0	3	3
351	B:B:E138	B:B:V135	4.28	No	No	0	6	4
352	B:B:R137	B:B:S136	3.95	No	No	0	5	4
353	B:B:G174	B:B:R137	3	No	No	0	4	5
354	B:B:L139	B:B:W169	12.53	No	Yes	0	9	8
355	B:B:H142	B:B:L146	3.86	Yes	No	0	9	7
356	B:B:H142	B:B:T159	6.85	Yes	Yes	10	9	9
357	B:B:H142	B:B:S161	11.16	Yes	No	10	9	9
358	B:B:D163	B:B:H142	3.78	Yes	Yes	10	9	9
359	B:B:H142	B:B:W169	10.58	Yes	Yes	10	9	8
360	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
361	B:B:S147	B:B:Y145	6.36	No	Yes	0	9	8
362	B:B:D186	B:B:Y145	3.45	No	Yes	0	9	8
363	B:B:M188	B:B:Y145	4.79	No	Yes	0	8	8
364	B:B:C148	B:B:R150	4.18	No	No	0	6	6
365	B:B:C148	B:B:L190	4.76	No	No	0	6	5
366	B:B:C149	B:B:T159	3.38	Yes	Yes	0	8	9
367	B:B:L192	B:B:R150	6.07	No	No	0	5	6
368	B:B:F151	B:B:I157	8.79	Yes	No	0	9	7
369	B:B:L152	B:B:Q156	3.99	Yes	No	0	3	5
370	B:B:L152	B:B:V158	8.94	Yes	No	0	3	5
371	B:B:L152	B:B:L192	4.15	Yes	No	0	3	5
372	B:B:E172	B:B:N155	15.77	No	No	0	6	3
373	B:B:L168	B:B:Q156	7.99	No	No	0	6	5
374	B:B:T159	B:B:W169	4.85	Yes	Yes	10	9	8
375	B:B:C166	B:B:S160	3.44	No	No	7	8	6
376	B:B:S160	B:B:V187	8.08	No	No	7	6	9
377	B:B:L190	B:B:S160	7.51	No	No	0	5	6
378	B:B:D163	B:B:S161	8.83	Yes	No	10	9	9
379	B:B:D186	B:B:G162	5.03	No	No	0	9	9
380	B:B:D163	B:B:T165	10.12	Yes	No	0	9	7
381	B:B:T165	B:B:T181	4.71	No	No	0	7	2
382	B:B:C166	B:B:V187	5.12	No	No	7	8	9
383	B:B:A167	B:B:W169	5.19	No	Yes	10	4	8
384	B:B:A167	B:B:Q176	4.55	No	No	10	4	4
385	B:B:Q176	B:B:W169	17.52	No	Yes	10	4	8
386	B:B:D170	B:B:E172	6.5	No	No	24	9	6
387	B:B:D170	B:B:T173	4.34	No	Yes	24	9	5
388	B:B:D170	B:B:T177	11.56	No	No	0	9	4
389	B:B:E172	B:B:T173	8.47	No	Yes	24	6	5
390	B:B:Q176	B:B:T179	5.67	No	No	0	4	4
391	B:B:T177	B:B:T178	4.71	No	No	0	4	4
392	B:B:F180	B:B:T178	7.78	Yes	No	0	7	4
393	B:B:F180	B:B:F199	8.57	Yes	No	7	7	9
394	B:B:F180	B:B:W211	12.03	Yes	Yes	7	7	8
395	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
396	B:B:H183	B:B:V187	6.92	Yes	No	7	9	9
397	B:B:H183	B:B:S201	6.97	Yes	No	7	9	9
398	B:B:A203	B:B:H183	5.85	No	Yes	0	8	9
399	B:B:H183	B:B:K209	20.96	Yes	Yes	7	9	6
400	B:B:H183	B:B:W211	11.64	Yes	Yes	7	9	8
401	B:B:D205	B:B:T184	5.78	No	No	0	9	3
402	B:B:C204	B:B:M188	4.86	No	No	0	7	8
403	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
404	B:B:S191	B:B:V200	4.85	No	Yes	2	8	6
405	B:B:I232	B:B:S191	7.74	Yes	No	2	8	8
406	B:B:F234	B:B:S191	7.93	Yes	No	2	5	8
407	B:B:A193	B:B:D195	3.09	No	No	0	4	5
408	B:B:A193	B:B:F234	8.32	No	Yes	0	4	5
409	B:B:G238	B:B:P194	4.06	No	No	0	7	4
410	B:B:D195	B:B:R197	3.57	No	Yes	0	5	5
411	B:B:L198	B:B:R197	3.64	Yes	Yes	2	3	5
412	B:B:D212	B:B:R197	5.96	Yes	Yes	2	9	5
413	B:B:R197	B:B:R214	14.93	Yes	No	2	5	9
414	B:B:L198	B:B:L210	4.15	Yes	Yes	2	3	5
415	B:B:D212	B:B:L198	5.43	Yes	Yes	2	9	3
416	B:B:L198	B:B:R219	3.64	Yes	No	2	3	5
417	B:B:F199	B:B:W211	8.02	No	Yes	7	9	8
418	B:B:L210	B:B:V200	5.96	Yes	Yes	2	5	6
419	B:B:I232	B:B:V200	4.61	Yes	Yes	2	8	6
420	B:B:F234	B:B:V200	6.55	Yes	Yes	2	5	6
421	B:B:F241	B:B:V200	18.35	Yes	Yes	2	6	6
422	B:B:S201	B:B:W211	7.41	No	Yes	7	9	8
423	B:B:A203	B:B:D205	4.63	No	No	0	8	9
424	B:B:C204	B:B:D228	10.89	No	No	0	7	9
425	B:B:D205	B:B:S207	8.83	No	No	0	9	5
426	B:B:K209	B:B:W211	9.28	Yes	Yes	7	6	8
427	B:B:C218	B:B:K209	4.85	No	Yes	7	5	6
428	B:B:K209	B:B:T221	4.5	Yes	No	0	6	7
429	B:B:L210	B:B:R219	6.07	Yes	No	2	5	5
430	B:B:L210	B:B:L255	4.15	Yes	No	0	5	6
431	B:B:C218	B:B:W211	6.53	No	Yes	7	5	8
432	B:B:D212	B:B:R214	4.76	Yes	No	2	9	9
433	B:B:D212	B:B:E215	7.8	Yes	No	0	9	3
434	B:B:D212	B:B:R219	5.96	Yes	No	2	9	5
435	B:B:E215	B:B:M217	6.77	No	No	0	3	3
436	B:B:C218	G:G:Q18	7.63	No	No	0	5	9
437	B:B:F222	B:B:Q220	14.05	No	No	0	8	7
438	B:B:D258	B:B:Q220	14.36	No	No	0	7	7
439	B:B:Q220	G:G:I25	5.49	No	No	0	7	2
440	B:B:T221	G:G:E22	8.47	No	No	0	7	9
441	B:B:F222	B:B:F241	13.93	No	Yes	2	8	6
442	B:B:F222	B:B:F253	10.72	No	Yes	2	8	6
443	B:B:G224	B:B:R251	3	No	Yes	0	6	8
444	B:B:H225	B:B:I229	15.91	Yes	No	2	9	7
445	B:B:H225	B:B:T243	10.95	Yes	Yes	2	9	8
446	B:B:H225	B:B:S245	9.76	Yes	Yes	2	9	9
447	B:B:H225	B:B:R251	16.93	Yes	Yes	2	9	8
448	B:B:F253	B:B:H225	4.53	Yes	Yes	2	6	9
449	B:B:S227	B:B:S245	3.26	No	Yes	0	6	9
450	B:B:I229	B:B:T243	3.04	No	Yes	2	7	8
451	B:B:I229	B:B:S245	3.1	No	Yes	2	7	9
452	B:B:D246	B:B:N230	13.46	No	No	0	9	9
453	B:B:A231	B:B:V276	3.39	No	No	0	5	6
454	B:B:F241	B:B:I232	3.77	Yes	Yes	2	6	8
455	B:B:I232	B:B:T243	4.56	Yes	Yes	2	8	8
456	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
457	B:B:F235	B:B:P236	10.11	Yes	Yes	19	6	7
458	B:B:F235	B:B:F278	9.65	Yes	Yes	19	6	7
459	B:B:F235	B:B:G282	3.01	Yes	No	19	6	9
460	B:B:F235	G:G:L37	3.65	Yes	No	0	6	7
461	B:B:F278	B:B:P236	5.78	Yes	Yes	19	7	7
462	B:B:G282	B:B:P236	4.06	No	Yes	19	9	7
463	B:B:P236	G:G:Y40	4.17	Yes	No	0	7	6
464	B:B:N237	B:B:N239	8.17	No	No	0	5	2
465	B:B:N237	G:G:Y40	12.79	No	No	0	5	6
466	B:B:N239	B:B:R256	8.44	No	Yes	0	2	9
467	B:B:F241	B:B:F253	8.57	Yes	Yes	2	6	6
468	B:B:F241	B:B:L255	3.65	Yes	No	0	6	6
469	B:B:A242	B:B:F278	4.16	No	Yes	0	4	7
470	B:B:F253	B:B:T243	5.19	Yes	Yes	2	6	8
471	B:B:G244	B:B:I273	3.53	No	No	0	5	6
472	B:B:D247	B:B:S245	8.83	No	Yes	0	9	9
473	B:B:D247	B:B:T249	7.23	No	No	0	9	6
474	B:B:D247	B:B:R251	3.57	No	Yes	0	9	8
475	B:B:T249	B:B:T263	4.71	No	No	0	6	1
476	B:B:S265	B:B:T249	4.8	No	No	0	2	6
477	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
478	B:B:F253	B:B:R251	7.48	Yes	Yes	2	6	8
479	B:B:E260	B:B:R251	17.45	No	Yes	2	6	8
480	B:B:L252	B:B:Y264	3.52	No	Yes	0	7	5
481	B:B:E260	B:B:F253	5.83	No	Yes	2	6	6
482	B:B:D254	B:B:R256	5.96	Yes	Yes	0	9	9
483	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
484	B:B:D254	B:B:L261	4.07	Yes	No	0	9	5
485	B:B:D254	G:G:A33	4.63	Yes	No	0	9	7
486	B:B:R256	G:G:I28	10.02	Yes	No	0	9	4
487	B:B:R256	G:G:D36	5.96	Yes	No	0	9	5
488	B:B:Q259	G:G:V30	4.3	No	No	0	6	8
489	B:B:E260	B:B:T263	9.88	No	No	0	6	1
490	B:B:A302	B:B:M262	3.22	No	No	0	2	4
491	B:B:W297	B:B:Y264	7.72	No	Yes	0	8	5
492	B:B:A302	B:B:Y264	4	No	Yes	0	2	5
493	B:B:H266	B:B:N268	11.48	No	No	14	4	4
494	B:B:H266	B:B:R304	9.03	No	No	14	4	5
495	B:B:I269	B:B:N268	7.08	No	No	0	4	4
496	B:B:N268	B:B:R304	8.44	No	No	14	4	5
497	B:B:I269	B:B:Y289	7.25	No	Yes	0	4	7
498	B:B:C271	B:B:D290	6.22	No	No	0	5	6
499	B:B:C271	B:B:D291	4.67	No	No	0	5	8
500	B:B:I273	B:B:Y289	7.25	No	Yes	0	6	7
501	B:B:S275	B:B:T274	3.2	No	No	0	8	8
502	B:B:D290	B:B:T274	4.34	No	No	0	6	8
503	B:B:T274	B:B:V315	3.17	No	No	0	8	7
504	B:B:L318	B:B:S275	9.01	No	No	0	6	8
505	B:B:L285	B:B:V276	4.47	No	No	0	6	6
506	B:B:L318	B:B:S277	3	No	No	0	6	5
507	B:B:S277	B:B:V320	4.85	No	No	0	5	7
508	B:B:F278	B:B:L285	12.18	Yes	No	0	7	6
509	B:B:S279	G:G:D48	4.42	No	Yes	25	9	9
510	B:B:S279	G:G:L50	6.01	No	No	25	9	9
511	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
512	B:B:D298	B:B:R283	9.53	Yes	No	12	9	9
513	B:B:L300	B:B:R283	15.79	Yes	No	12	6	9
514	B:B:L286	B:B:V327	4.47	No	No	0	7	6
515	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
516	B:B:C294	B:B:G288	3.92	No	No	0	5	7
517	B:B:G288	B:B:V315	3.68	No	No	0	7	7
518	B:B:D291	B:B:Y289	3.45	No	Yes	0	8	7
519	B:B:N295	B:B:Y289	9.3	Yes	Yes	14	6	7
520	B:B:W297	B:B:Y289	8.68	No	Yes	14	8	7
521	B:B:D290	B:B:R314	23.82	No	No	0	6	8
522	B:B:D291	B:B:N293	13.46	No	No	0	8	5
523	B:B:F292	R:R:R317	5.34	No	No	0	4	4
524	B:B:N295	B:B:W297	3.39	Yes	No	14	6	8
525	B:B:N295	B:B:R304	6.03	Yes	No	14	6	5
526	B:B:N295	B:B:V307	4.43	Yes	No	0	6	3
527	B:B:A305	B:B:V296	3.39	No	No	0	4	5
528	B:B:D298	B:B:L300	5.43	Yes	Yes	12	9	6
529	B:B:D298	B:B:K301	9.68	Yes	Yes	0	9	5
530	B:B:L300	G:G:M38	4.24	Yes	Yes	12	6	4
531	B:B:D303	B:B:K301	6.91	No	Yes	0	2	5
532	B:B:L308	B:B:W339	9.11	No	Yes	0	7	9
533	B:B:H311	B:B:T329	8.21	Yes	No	0	9	8
534	B:B:H311	B:B:S331	12.55	Yes	No	5	9	9
535	B:B:D333	B:B:H311	6.3	No	Yes	5	9	9
536	B:B:H311	B:B:K337	7.86	Yes	Yes	5	9	6
537	B:B:D312	R:R:R317	9.53	No	No	0	5	4
538	B:B:N313	B:B:W332	7.91	No	Yes	0	7	9
539	B:B:R314	B:B:W332	7	No	Yes	1	8	9
540	B:B:C317	B:B:S316	3.44	No	No	0	7	9
541	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
542	B:B:V320	B:B:V327	4.81	No	No	0	7	6
543	B:B:D323	B:B:T321	8.67	No	No	4	7	7
544	B:B:D323	B:B:M325	4.16	No	Yes	4	7	5
545	B:B:M325	G:G:P49	5.03	Yes	No	0	5	7
546	B:B:M325	G:G:V54	3.04	Yes	No	4	5	6
547	B:B:M325	G:G:E58	5.41	Yes	No	4	5	5
548	B:B:M325	G:G:N59	4.21	Yes	Yes	4	5	9
549	B:B:M325	G:G:P60	6.71	Yes	Yes	4	5	9
550	B:B:M325	G:G:F61	3.73	Yes	Yes	4	5	8
551	B:B:A326	B:B:N340	4.69	No	No	4	7	9
552	B:B:A326	G:G:F61	5.55	No	Yes	4	7	8
553	B:B:T329	B:B:W339	3.64	No	Yes	0	8	9
554	B:B:G330	B:B:L336	3.42	No	No	0	5	7
555	B:B:D333	B:B:S331	8.83	No	No	5	9	9
556	B:B:D333	B:B:F335	8.36	No	Yes	0	9	4
557	B:B:F335	B:B:S334	5.28	Yes	No	0	4	4
558	B:B:S334	R:R:R62	5.27	No	No	0	4	5
559	B:B:F335	R:R:R60	5.34	Yes	Yes	0	4	5
560	B:B:K337	B:B:W339	4.64	Yes	Yes	5	6	9
561	B:B:K337	R:R:R60	7.43	Yes	Yes	5	6	5
562	B:B:I338	G:G:F61	5.02	No	Yes	0	5	8
563	B:B:N340	G:G:N59	6.81	No	Yes	4	9	9
564	B:B:N340	G:G:F61	4.83	No	Yes	4	9	8
565	G:G:I9	G:G:R13	5.01	No	No	0	2	6
566	G:G:M21	G:G:Q18	4.08	No	No	0	1	9
567	G:G:E22	G:G:Q18	12.74	No	No	0	9	9
568	G:G:I28	G:G:K32	8.72	No	No	0	4	5
569	G:G:H44	G:G:Y40	26.13	No	No	0	6	6
570	G:G:E47	G:G:H44	9.85	No	No	0	3	6
571	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
572	G:G:D48	G:G:L50	4.07	Yes	No	25	9	9
573	G:G:D48	G:G:L51	8.14	Yes	Yes	0	9	6
574	G:G:P55	G:G:V54	3.53	No	No	0	5	6
575	G:G:E58	G:G:V54	5.7	No	No	4	5	6
576	G:G:P55	G:G:S57	3.56	No	No	0	5	6
577	G:G:N59	G:G:P60	6.52	Yes	Yes	4	9	9
578	G:G:F61	G:G:N59	6.04	Yes	Yes	4	8	9
579	G:G:F61	G:G:P60	4.33	Yes	Yes	4	8	9
580	R:R:E15	R:R:L10	3.98	No	No	0	7	7
581	R:R:C11	R:R:P12	3.77	No	No	0	7	6
582	R:R:C11	R:R:L187	3.17	No	No	0	7	4
583	R:R:C11	R:R:C199	7.28	No	No	0	7	2
584	R:R:H273	R:R:P12	3.05	Yes	No	0	1	6
585	R:R:I13	R:R:M17	4.37	No	Yes	26	7	7
586	R:R:I13	R:R:Y183	13.3	No	Yes	26	7	4
587	R:R:H273	R:R:I13	5.3	Yes	No	0	1	7
588	R:R:L14	R:R:S18	3	No	No	0	7	7
589	R:R:D171	R:R:L14	4.07	Yes	No	0	5	7
590	R:R:L14	R:R:Y183	8.21	No	Yes	0	7	4
591	R:R:E15	R:R:R195	4.65	No	No	0	7	2
592	R:R:Q16	R:R:R279	4.67	No	Yes	0	7	1
593	R:R:M17	R:R:Y183	8.38	Yes	Yes	26	7	4
594	R:R:M17	R:R:W283	5.82	Yes	Yes	0	7	4
595	R:R:R19	R:R:S18	6.59	No	No	0	5	7
596	R:R:L20	R:R:S22	3	No	No	0	5	4
597	R:R:L20	R:R:W283	11.39	No	Yes	0	5	4
598	R:R:H23	R:R:R179	5.64	No	No	0	5	1
599	R:R:S24	R:R:Y30	6.36	No	No	0	4	2
600	R:R:T26	R:R:Y30	7.49	No	No	0	3	2
601	R:R:H33	R:R:Y30	4.36	No	No	0	3	2
602	R:R:G178	R:R:V36	3.68	No	No	0	5	4
603	R:R:H39	R:R:S291	4.18	No	No	0	8	5
604	R:R:F294	R:R:H39	12.44	Yes	No	0	6	8
605	R:R:A42	R:R:F295	4.16	No	No	0	7	5
606	R:R:P85	R:R:S43	7.13	No	No	0	9	7
607	R:R:L47	R:R:S81	10.51	Yes	No	0	6	6
608	R:R:E49	R:R:V298	5.7	No	No	0	7	8
609	R:R:E49	R:R:P301	3.14	No	Yes	0	7	9
610	R:R:E49	R:R:V302	4.28	No	No	0	7	6
611	R:R:D77	R:R:N50	13.46	No	No	15	9	9
612	R:R:L78	R:R:N50	8.24	Yes	No	15	8	9
613	R:R:N50	R:R:P301	3.26	No	Yes	15	9	9
614	R:R:I53	R:R:V52	3.07	Yes	No	0	9	6
615	R:R:A74	R:R:I53	3.25	No	Yes	0	9	9
616	R:R:I53	R:R:P301	3.39	Yes	Yes	0	9	9
617	R:R:I53	R:R:V305	4.61	Yes	No	0	9	7
618	R:R:A74	R:R:L54	4.73	No	No	0	9	7
619	R:R:R60	R:R:V56	3.92	Yes	Yes	5	5	7
620	R:R:K314	R:R:V56	4.55	Yes	Yes	5	4	7
621	R:R:M61	R:R:V57	9.13	Yes	No	5	6	7
622	R:R:T67	R:R:V57	3.17	No	No	5	7	7
623	R:R:L71	R:R:V57	7.45	No	No	0	6	7
624	R:R:K314	R:R:R60	12.38	Yes	Yes	5	4	5
625	R:R:M61	R:R:T67	4.52	Yes	No	5	6	7
626	R:R:M311	R:R:M61	4.33	Yes	Yes	0	8	6
627	R:R:K314	R:R:M61	8.64	Yes	Yes	5	4	6
628	R:R:L71	R:R:Q63	3.99	No	No	0	6	5
629	R:R:T64	R:R:T67	10.99	No	No	0	7	7
630	R:R:V65	R:R:W69	3.68	No	Yes	0	5	7
631	R:R:R143	R:R:V65	10.46	No	No	0	7	5
632	R:R:H149	R:R:T68	10.95	No	No	0	4	7
633	R:R:A124	R:R:W69	5.19	No	Yes	0	7	7
634	R:R:I125	R:R:W69	8.22	No	Yes	0	8	7
635	R:R:A148	R:R:W69	3.89	No	Yes	0	7	7
636	R:R:V151	R:R:W69	3.68	No	Yes	0	5	7
637	R:R:C152	R:R:W69	5.22	No	Yes	0	7	7
638	R:R:M311	R:R:V70	6.09	Yes	No	0	8	8
639	R:R:C152	R:R:H72	14.74	No	No	0	7	9
640	R:R:H72	R:R:W156	3.17	No	Yes	0	9	9
641	R:R:L73	R:R:S118	3	No	No	0	9	9
642	R:R:L73	R:R:Y304	3.52	No	Yes	0	9	9
643	R:R:L75	R:R:L79	4.15	No	No	0	6	6
644	R:R:N114	R:R:S76	4.47	Yes	Yes	0	8	8
645	R:R:A117	R:R:S76	3.42	No	Yes	28	7	8
646	R:R:S118	R:R:S76	3.26	No	Yes	0	9	8
647	R:R:S76	R:R:W156	4.94	Yes	Yes	28	8	9
648	R:R:D77	R:R:S297	11.78	No	No	0	9	9
649	R:R:D77	R:R:P301	6.44	No	Yes	15	9	9
650	R:R:A80	R:R:N114	6.25	No	Yes	0	7	8
651	R:R:L84	R:R:S83	3	Yes	No	0	8	6
652	R:R:I110	R:R:S83	9.29	No	No	0	5	6
653	R:R:L84	R:R:P85	3.28	Yes	No	0	8	9
654	R:R:H107	R:R:L84	3.86	No	Yes	0	5	8
655	R:R:F294	R:R:L84	8.53	Yes	Yes	0	6	8
656	R:R:F103	R:R:T88	5.19	Yes	No	0	6	7
657	R:R:D177	R:R:Y89	17.24	No	No	0	3	4
658	R:R:F90	R:R:L91	6.09	No	No	0	5	5
659	R:R:F103	R:R:L91	8.53	Yes	No	0	6	5
660	R:R:E98	R:R:F103	9.33	No	Yes	0	3	6
661	R:R:K105	R:R:T101	3	Yes	No	0	7	4
662	R:R:D171	R:R:T101	4.34	Yes	No	0	5	4
663	R:R:K105	R:R:T102	4.5	Yes	No	0	7	3
664	R:R:C104	R:R:R170	5.57	No	Yes	3	9	5
665	R:R:C104	R:R:T172	10.14	No	No	0	9	6
666	R:R:C104	R:R:C182	7.28	No	No	3	9	9
667	R:R:K105	R:R:R170	4.95	Yes	Yes	0	7	5
668	R:R:I110	R:R:L106	7.14	No	No	0	5	4
669	R:R:C182	R:R:H107	10.32	No	No	0	9	5
670	R:R:F112	R:R:S108	6.61	Yes	No	0	5	5
671	R:R:R170	R:R:S108	15.81	Yes	No	0	5	5
672	R:R:F167	R:R:S109	7.93	No	No	0	4	5
673	R:R:I110	R:R:N114	5.66	No	Yes	0	5	8
674	R:R:F111	R:R:F112	4.29	No	Yes	3	6	5
675	R:R:F111	R:R:Y262	10.32	No	Yes	3	6	7
676	R:R:F111	R:R:F294	7.5	No	Yes	0	6	6
677	R:R:F112	R:R:Y166	13.41	Yes	Yes	3	5	4
678	R:R:F112	R:R:K210	4.96	Yes	Yes	3	5	5
679	R:R:F112	R:R:Y262	5.16	Yes	Yes	3	5	7
680	R:R:L113	R:R:W156	6.83	No	Yes	0	5	9
681	R:R:L113	R:R:V160	4.47	No	No	0	5	4
682	R:R:F116	R:R:M115	4.98	No	Yes	0	7	8
683	R:R:A214	R:R:M115	4.83	No	Yes	0	6	8
684	R:R:M115	R:R:W259	12.8	Yes	Yes	0	8	8
685	R:R:H263	R:R:M115	5.25	Yes	Yes	0	8	8
686	R:R:F116	R:R:F120	3.22	No	No	0	7	6
687	R:R:F116	R:R:L213	6.09	No	No	0	7	4
688	R:R:A117	R:R:W156	7.78	No	Yes	28	7	9
689	R:R:G119	R:R:P218	4.06	No	No	0	7	9
690	R:R:F120	R:R:L155	9.74	No	No	0	6	7
691	R:R:L122	R:R:Y304	5.86	No	Yes	0	9	9
692	R:R:P218	R:R:S123	3.56	No	No	0	9	7
693	R:R:I221	R:R:S123	4.64	Yes	No	0	7	7
694	R:R:I125	R:R:R129	6.26	No	No	27	8	9
695	R:R:I125	R:R:Y304	3.63	No	Yes	27	8	9
696	R:R:I222	R:R:S126	9.29	No	No	0	8	9
697	R:R:S126	R:R:S225	3.26	No	No	0	9	8
698	R:R:I221	R:R:L127	4.28	Yes	No	0	7	6
699	R:R:L127	W:W:?1	6.2	No	Yes	0	6	0
700	R:R:D128	R:R:Q132	10.44	No	Yes	11	8	7
701	R:R:D128	R:R:R143	7.15	No	No	11	8	7
702	R:R:D128	W:W:?1	6.08	No	Yes	11	8	0
703	R:R:R129	R:R:Y304	3.09	No	Yes	27	9	9
704	R:R:C130	R:R:S225	3.44	No	No	0	8	8
705	R:R:Q132	R:R:R143	11.68	Yes	No	11	7	7
706	R:R:V133	R:R:V229	12.83	No	No	0	8	8
707	R:R:R135	R:R:V134	5.23	No	No	0	6	8
708	R:R:R232	R:R:V134	9.15	No	No	0	5	8
709	R:R:N141	R:R:V137	4.43	No	No	0	5	6
710	R:R:H142	R:R:W138	21.16	No	No	11	4	4
711	R:R:W138	W:W:?1	8.5	No	Yes	11	4	0
712	R:R:H142	R:R:N141	6.38	No	No	0	4	5
713	R:R:H142	W:W:?1	27.83	No	Yes	11	4	0
714	R:R:A147	W:W:?1	7.06	No	Yes	0	3	0
715	R:R:K150	W:W:?1	7.37	No	Yes	0	2	0
716	R:R:T163	R:R:V160	3.17	No	No	0	7	4
717	R:R:L213	R:R:N162	9.61	No	No	0	4	5
718	R:R:P165	R:R:V164	3.53	No	No	0	7	4
719	R:R:Y166	R:R:Y184	9.93	Yes	Yes	3	4	4
720	R:R:L206	R:R:Y166	14.07	Yes	Yes	3	5	4
721	R:R:S209	R:R:Y166	6.36	No	Yes	0	4	4
722	R:R:K210	R:R:Y166	7.17	Yes	Yes	3	5	4
723	R:R:F169	R:R:V168	11.8	No	No	0	5	4
724	R:R:L189	R:R:V168	4.47	No	No	0	5	4
725	R:R:F169	R:R:V186	22.28	No	No	0	5	5
726	R:R:C182	R:R:R170	5.57	No	Yes	3	9	5
727	R:R:R170	R:R:Y184	15.43	Yes	Yes	3	5	4
728	R:R:D171	R:R:N185	6.73	Yes	No	0	5	4
729	R:R:D171	R:R:L188	4.07	Yes	No	0	5	7
730	R:R:M181	R:R:T172	3.01	No	No	0	4	6
731	R:R:I173	R:R:S174	3.1	No	No	0	3	1
732	R:R:D177	R:R:G178	6.71	No	No	0	3	5
733	R:R:N185	R:R:Y183	3.49	No	Yes	0	4	4
734	R:R:Q203	R:R:Y184	16.91	No	Yes	0	3	4
735	R:R:L206	R:R:Y184	11.72	Yes	Yes	3	5	4
736	R:R:L187	R:R:N185	10.98	No	No	0	4	4
737	R:R:R202	R:R:V186	11.77	No	No	0	3	5
738	R:R:N190	R:R:R202	4.82	No	No	0	7	3
739	R:R:G192	R:R:P193	4.06	No	No	0	5	5
740	R:R:A197	R:R:D194	4.63	No	No	0	1	1
741	R:R:D194	R:R:T198	5.78	No	No	0	1	3
742	R:R:D196	R:R:H273	8.82	No	Yes	0	2	1
743	R:R:N200	R:R:V204	4.43	No	No	0	1	2
744	R:R:H273	R:R:N200	16.58	Yes	No	0	1	1
745	R:R:K210	R:R:Y262	7.17	Yes	Yes	3	5	7
746	R:R:H263	R:R:K210	9.17	Yes	Yes	3	8	5
747	R:R:K210	R:R:S266	7.65	Yes	No	0	5	5
748	R:R:F211	R:R:L212	3.65	Yes	No	3	6	6
749	R:R:F211	R:R:F215	9.65	Yes	Yes	3	6	9
750	R:R:F211	R:R:L216	8.53	Yes	No	3	6	5
751	R:R:F211	R:R:H263	9.05	Yes	Yes	3	6	8
752	R:R:L212	R:R:L216	4.15	No	No	3	6	5
753	R:R:F215	R:R:L219	3.65	Yes	No	0	9	5
754	R:R:F215	R:R:G260	6.02	Yes	No	0	9	5
755	R:R:F215	R:R:H263	3.39	Yes	Yes	3	9	8
756	R:R:P218	R:R:V217	3.53	No	No	0	9	5
757	R:R:I221	R:R:V217	3.07	Yes	No	0	7	5
758	R:R:F255	R:R:L219	3.65	No	No	0	9	5
759	R:R:I221	R:R:S224	3.1	Yes	No	0	7	4
760	R:R:H226	R:R:I222	5.3	No	No	0	9	8
761	R:R:H226	R:R:V248	16.61	No	No	0	9	7
762	R:R:F244	R:R:V229	3.93	Yes	No	0	7	8
763	R:R:F244	R:R:S230	5.28	Yes	No	0	7	5
764	R:R:H235	R:R:L231	3.86	No	No	0	4	4
765	R:R:L233	R:R:R238	4.86	No	Yes	0	8	3
766	R:R:L233	R:R:R240	8.5	No	No	0	8	5
767	R:R:Q234	R:R:R240	8.18	No	No	0	5	5
768	R:R:R238	R:R:R239	6.4	Yes	No	23	3	4
769	R:R:F244	R:R:R240	4.28	Yes	No	0	7	5
770	R:R:R243	R:R:R246	5.33	No	No	0	7	5
771	R:R:F244	R:R:V248	6.55	Yes	No	0	7	7
772	R:R:L247	R:R:T307	4.42	No	No	0	7	7
773	R:R:A250	R:R:L303	3.15	No	No	0	6	8
774	R:R:V251	R:R:Y304	8.83	No	Yes	0	8	9
775	R:R:F255	R:R:W259	13.03	No	Yes	0	9	8
776	R:R:C258	R:R:N296	7.87	No	No	0	8	9
777	R:R:A293	R:R:W259	3.89	No	Yes	0	8	8
778	R:R:N296	R:R:W259	14.69	No	Yes	0	9	8
779	R:R:G260	R:R:P261	4.06	No	No	0	5	9
780	R:R:P261	R:R:V289	3.53	No	No	0	9	7
781	R:R:H263	R:R:Y262	5.44	Yes	Yes	3	8	7
782	R:R:F265	R:R:G285	4.52	No	No	0	5	5
783	R:R:F265	R:R:V289	5.24	No	No	0	5	7
784	R:R:E269	R:R:V282	8.56	No	No	0	5	4
785	R:R:P276	R:R:R279	5.76	No	Yes	0	1	1
786	R:R:R279	R:R:W283	3	Yes	Yes	0	1	4
787	R:R:L286	R:R:P287	3.28	No	No	0	5	4
788	R:R:F294	R:R:T290	5.19	Yes	No	0	6	6
789	R:R:F295	R:R:S291	3.96	No	No	0	5	5
790	R:R:N296	R:R:N300	14.98	No	No	0	9	9
791	R:R:C308	R:R:M311	4.86	No	Yes	0	8	8
792	R:R:D310	R:R:P309	3.22	No	No	0	5	5
793	R:R:D310	R:R:M311	6.93	No	Yes	0	5	8
794	R:R:R313	R:R:R317	26.66	No	No	0	5	4
795	R:R:L319	R:R:R316	3.64	No	No	0	7	5
796	R:R:R316	R:R:R320	3.2	No	No	0	5	5
797	R:R:S318	R:R:T321	3.2	No	No	0	4	3
798	R:R:L323	R:R:R320	7.29	No	No	0	5	5
799	R:R:E324	R:R:S325	4.31	No	No	0	4	5
800	B:B:L284	B:B:V40	2.98	No	Yes	0	5	3
801	B:B:V40	G:G:L51	2.98	Yes	Yes	0	3	6
802	B:B:L126	B:B:V112	2.98	No	No	0	5	8
803	B:B:L152	B:B:V213	2.98	Yes	No	0	3	4
804	B:B:L286	B:B:V296	2.98	No	No	0	7	5
805	R:R:L158	R:R:V154	2.98	No	No	0	5	3
806	R:R:L212	R:R:V208	2.98	No	No	0	6	4
807	R:R:L268	R:R:V264	2.98	No	No	0	5	6
808	R:R:L306	R:R:V305	2.98	No	No	0	7	7
809	A:A:L5	A:A:T4	2.95	Yes	No	0	2	4
810	B:B:L51	B:B:T87	2.95	No	No	0	9	5
811	B:B:L318	B:B:T329	2.95	No	No	0	6	8
812	B:B:D246	B:B:S227	2.94	No	No	0	9	6
813	B:B:D212	B:B:V213	2.92	Yes	No	0	9	4
814	R:R:P12	R:R:R195	2.88	No	No	0	6	2
815	A:A:E28	R:R:V145	2.85	No	No	0	4	1
816	A:A:I344	A:A:L348	2.85	No	No	0	6	9
817	B:B:L4	G:G:I9	2.85	No	No	0	4	2
818	B:B:Q175	B:B:T173	2.83	No	Yes	0	4	5
819	A:A:E28	R:R:T144	2.82	No	No	0	4	6
820	A:A:E297	A:A:T295	2.82	No	No	0	4	5
821	A:A:E298	A:A:T295	2.82	No	No	0	4	5
822	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
823	A:A:K51	A:A:N47	2.8	No	No	0	9	9
824	A:A:D231	A:A:I285	2.8	Yes	No	0	9	3
825	B:B:D118	B:B:I120	2.8	No	No	0	9	6
826	B:B:K127	B:B:N125	2.8	No	No	0	4	4
827	B:B:C233	B:B:F278	2.79	No	Yes	0	3	7
828	R:R:C59	R:R:F55	2.79	No	No	0	5	4
829	A:A:K209	B:B:D228	2.77	No	No	0	8	9
830	A:A:D261	A:A:K349	2.77	No	No	0	4	5
831	A:A:A299	A:A:F274	2.77	No	Yes	0	7	9
832	B:B:L261	B:B:L30	2.77	No	No	0	5	5
833	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
834	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
835	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
836	B:B:L252	B:B:L261	2.77	No	No	0	7	5
837	B:B:D312	R:R:K314	2.77	No	Yes	0	5	4
838	R:R:L41	R:R:L44	2.77	No	No	0	5	6
839	R:R:L47	R:R:L78	2.77	Yes	Yes	15	6	8
840	R:R:L54	R:R:L71	2.77	No	No	0	7	6
841	R:R:L121	R:R:L73	2.77	No	No	0	7	9
842	R:R:A159	R:R:F120	2.77	No	No	0	8	6
843	R:R:H149	R:R:V145	2.77	No	No	0	4	1
844	R:R:L306	R:R:L312	2.77	No	No	0	7	7
845	R:R:H72	R:R:T68	2.74	No	No	0	9	7
846	R:R:E269	R:R:M17	2.71	No	Yes	0	5	7
847	G:G:E17	G:G:K14	2.7	No	No	0	6	4
848	B:B:E10	B:B:L14	2.65	No	Yes	0	8	8
849	A:A:F267	A:A:V335	2.62	Yes	No	0	9	8
850	R:R:R232	R:R:V133	2.62	No	No	0	5	8
851	B:B:D153	B:B:Q156	2.61	No	No	0	5	5
852	B:B:R134	B:B:T128	2.59	No	No	0	3	3
853	A:A:S263	A:A:Y320	2.54	No	Yes	0	7	7
854	B:B:I18	B:B:R22	2.51	No	No	0	7	6
855	A:A:M18	A:A:R21	2.48	No	No	0	4	4
856	R:R:F167	R:R:K105	2.48	No	Yes	0	4	7
857	B:B:S97	B:B:W99	2.47	No	Yes	0	8	9
858	R:R:F86	R:R:L44	2.44	No	No	0	7	6
859	R:R:F86	R:R:L47	2.44	No	Yes	0	7	6
860	R:R:F169	R:R:L206	2.44	No	Yes	0	5	5
861	B:B:L7	G:G:R13	2.43	No	No	0	8	6
862	A:A:I278	A:A:Y230	2.42	No	Yes	0	6	8
863	A:A:D20	A:A:R24	2.38	No	No	0	6	3
864	B:B:D258	G:G:R27	2.38	No	No	0	7	8
865	B:B:E130	B:B:R134	2.33	No	No	0	3	3
866	B:B:D154	B:B:Y111	2.3	No	No	0	6	4
867	A:A:E297	A:A:Y296	2.24	No	Yes	0	4	4
868	B:B:G115	B:B:G116	2.11	No	No	0	9	9
869	R:R:L131	W:W:?1	2.07	No	Yes	0	6	0
870	A:A:G352	R:R:P309	2.03	No	No	0	8	5
871	B:B:G324	G:G:P49	2.03	No	No	0	9	7
872	R:R:G192	R:R:P191	2.03	No	No	0	5	6
873	R:R:G242	R:R:P241	2.03	No	No	0	5	6
874	R:R:G285	R:R:P287	2.03	No	No	0	5	4
875	B:B:C204	B:B:G185	1.96	No	No	0	7	5
876	B:B:C271	B:B:G272	1.96	No	No	0	5	4
877	A:A:A41	A:A:G42	1.95	No	No	0	7	8
878	B:B:A140	B:B:G141	1.95	No	No	0	5	5
879	B:B:A208	B:B:G202	1.95	No	No	0	6	6
880	B:B:A309	B:B:G310	1.95	No	No	0	3	5
881	B:B:A106	B:B:P107	1.87	No	No	0	6	6
882	R:R:G40	R:R:S43	1.86	No	No	0	4	7
883	R:R:G100	R:R:S174	1.86	Yes	No	0	8	1
884	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
885	B:B:G306	B:B:V296	1.84	No	No	0	4	5
886	R:R:G46	R:R:V298	1.84	No	No	0	8	8
887	R:R:G242	R:R:V245	1.84	No	No	0	5	5
888	B:B:G131	B:B:T128	1.82	No	No	0	4	3
889	B:B:G185	B:B:T164	1.82	No	No	0	5	6
890	B:B:G174	B:B:T173	1.82	No	Yes	0	4	5
891	B:B:G182	B:B:T181	1.82	No	No	0	6	2
892	B:B:G224	B:B:T223	1.82	No	No	0	6	2
893	R:R:G100	R:R:T172	1.82	Yes	No	0	8	6
894	R:R:G192	R:R:T198	1.82	No	No	0	5	3
895	B:B:A104	B:B:C149	1.81	No	Yes	0	7	8
896	B:B:A113	B:B:C121	1.81	No	No	0	9	8
897	B:B:A113	B:B:C149	1.81	No	Yes	0	9	8
898	R:R:A228	R:R:C130	1.81	No	No	0	3	8
899	R:R:A254	R:R:A299	1.79	No	No	0	7	6
900	B:B:P107	B:B:T65	1.75	No	No	0	6	1
901	G:G:P53	G:G:T52	1.75	No	No	0	8	4
902	A:A:G202	A:A:K46	1.74	No	Yes	0	9	9
903	B:B:G324	B:B:K280	1.74	No	No	0	9	1
904	B:B:G310	B:B:K337	1.74	No	Yes	0	5	6
905	A:A:G27	B:B:L55	1.71	No	No	0	5	6
906	R:R:G46	R:R:L45	1.71	No	No	0	8	6
907	R:R:G51	R:R:L78	1.71	No	Yes	0	5	8
908	R:R:C308	R:R:V66	1.71	No	No	0	8	7
909	R:R:G100	R:R:L99	1.71	Yes	No	0	8	7
910	R:R:A207	R:R:S266	1.71	No	No	0	5	5
911	B:B:A11	G:G:V16	1.7	No	No	0	5	7
912	R:R:A270	R:R:V204	1.7	No	No	0	5	2
913	R:R:C308	R:R:T307	1.69	No	No	0	8	7
914	A:A:D26	A:A:G27	1.68	No	No	0	5	5
915	R:R:A146	R:R:T144	1.68	No	No	0	4	6
916	A:A:E216	A:A:G217	1.64	No	No	0	7	5
917	R:R:L206	R:R:P165	1.64	Yes	No	0	5	7
918	R:R:N190	R:R:P191	1.63	No	No	0	7	6
919	R:R:N275	R:R:P276	1.63	No	No	0	2	1
920	A:A:I19	B:B:A92	1.62	No	No	0	9	6
921	A:A:A220	A:A:I265	1.62	No	Yes	0	8	8
922	B:B:I33	G:G:A34	1.62	No	No	0	3	6
923	B:B:A248	B:B:I269	1.62	No	No	0	5	4
924	R:R:S318	R:R:V56	1.62	No	Yes	0	4	7
925	R:R:S318	R:R:V322	1.62	No	No	0	4	4
926	B:B:D38	B:B:P39	1.61	No	No	0	1	1
927	B:B:S31	B:B:T29	1.6	No	No	0	1	3
928	R:R:V248	R:R:V252	1.6	No	No	0	7	8
929	A:A:T187	A:A:V50	1.59	No	No	0	6	6
930	A:A:T187	A:A:V185	1.59	No	No	0	6	5
931	B:B:L300	G:G:C41	1.59	Yes	No	0	6	7
932	B:B:A299	B:B:L300	1.58	No	Yes	0	5	6
933	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
934	R:R:A82	R:R:L47	1.58	No	Yes	15	5	6
935	R:R:A82	R:R:L78	1.58	No	Yes	15	5	8
936	R:R:A207	R:R:L267	1.58	No	No	0	5	6
937	R:R:A254	R:R:L303	1.58	No	No	0	7	8
938	R:R:A272	R:R:L278	1.58	No	No	0	3	1
939	R:R:A274	R:R:N275	1.56	No	No	0	1	2
940	B:B:M262	B:B:S31	1.53	No	No	0	4	1
941	A:A:M198	A:A:V50	1.52	Yes	No	0	7	6
942	R:R:A139	R:R:Q132	1.52	No	Yes	0	5	7
943	R:R:F103	R:R:G100	1.51	Yes	Yes	0	6	8
944	R:R:F288	R:R:G285	1.51	No	No	0	5	5
945	A:A:K330	A:A:T327	1.5	No	No	0	4	8
946	B:B:L4	G:G:S8	1.5	No	No	0	4	4
947	R:R:L91	R:R:S96	1.5	No	No	0	5	4
948	R:R:G242	R:R:R246	1.5	No	No	0	5	5
949	A:A:L5	A:A:V13	1.49	Yes	No	0	2	3
950	R:R:L315	R:R:V52	1.49	No	No	0	5	6
951	R:R:L315	R:R:V56	1.49	No	Yes	0	5	7
952	R:R:L268	R:R:V282	1.49	No	No	0	5	4
953	R:R:L327	R:R:V326	1.49	No	No	0	4	5
954	B:B:I123	B:B:I171	1.47	No	No	0	6	6
955	B:B:I157	B:B:I171	1.47	No	No	0	7	6
956	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
957	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
958	G:G:A43	G:G:H44	1.46	No	No	0	4	6
959	R:R:D32	R:R:V36	1.46	No	No	0	4	4
960	A:A:I278	A:A:K279	1.45	No	No	0	6	2
961	A:A:E8	A:A:S6	1.44	No	No	0	5	7
962	B:B:E226	B:B:S227	1.44	No	No	0	3	6
963	R:R:P280	R:R:R279	1.44	No	Yes	0	2	1
964	B:B:I18	G:G:L19	1.43	No	No	0	7	9
965	A:A:K10	A:A:L5	1.41	No	Yes	0	3	2
966	B:B:L14	G:G:K20	1.41	Yes	No	0	8	6
967	A:A:M18	A:A:N22	1.4	No	No	0	4	4
968	B:B:K301	B:B:N35	1.4	Yes	No	0	5	1
969	B:B:R52	R:R:C59	1.39	No	No	0	7	5
970	R:R:H23	R:R:S22	1.39	No	No	0	5	4
971	A:A:D350	A:A:K349	1.38	No	No	0	4	5
972	G:G:A10	G:G:R13	1.38	No	No	0	2	6
973	G:G:A56	G:G:R62	1.38	No	No	0	4	7
974	R:R:A272	R:R:R279	1.38	No	Yes	0	3	1
975	R:R:L278	R:R:L281	1.38	No	No	0	1	2
976	B:B:I37	G:G:E42	1.37	No	No	0	2	1
977	R:R:L79	R:R:N114	1.37	No	Yes	0	6	8
978	R:R:L158	R:R:N162	1.37	No	No	0	5	5
979	A:A:E14	A:A:M18	1.35	No	No	0	3	4
980	B:B:E12	B:B:K15	1.35	No	No	0	4	6
981	A:A:E276	A:A:L273	1.33	No	No	0	5	6
982	B:B:L14	B:B:Q17	1.33	Yes	No	0	8	4
983	R:R:L231	R:R:Q234	1.33	No	No	0	4	5
984	R:R:R284	R:R:S22	1.32	No	No	0	1	4
985	R:R:R202	R:R:S201	1.32	No	No	0	3	1
986	R:R:D32	R:R:H33	1.26	No	No	0	4	3
987	R:R:S96	R:R:W97	1.24	No	No	0	4	9
988	R:R:L303	R:R:Y304	1.17	No	Yes	0	8	9
989	G:G:E63	G:G:R62	1.16	No	No	0	6	7
990	R:R:E324	R:R:R320	1.16	No	No	0	4	5
991	R:R:Q21	R:R:W283	1.1	No	Yes	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:L5	3.16	4	0	2
2	A:A:V34	5.2175	4	9	5
3	A:A:K46	5.238	5	20	9
4	A:A:F191	8.52	4	9	5
5	A:A:L194	6.565	4	9	4
6	A:A:F196	9.4025	4	9	7
7	A:A:K197	6.36	5	1	6
8	A:A:M198	4.8475	4	0	7
9	A:A:F199	8.685	4	1	5
10	A:A:Q204	5.514	5	1	9
11	A:A:W211	5.875	4	1	9
12	A:A:H213	7.4975	4	1	8
13	A:A:F215	8.4275	4	1	9
14	A:A:D229	4.8575	4	0	8
15	A:A:Y230	6.66286	7	17	8
16	A:A:D231	7.61	5	17	9
17	A:A:C254	4.3925	4	6	5
18	A:A:W258	10.0283	6	1	5
19	A:A:F259	6.5625	4	6	9
20	A:A:I264	5.2625	4	6	6
21	A:A:I265	4.134	5	16	8
22	A:A:L266	4.62	4	0	9
23	A:A:F267	4.47	6	16	9
24	A:A:N269	5.9525	4	0	9
25	A:A:F274	6.48	4	0	9
26	A:A:Y287	6.082	5	22	7
27	A:A:Y296	7.934	5	21	4
28	A:A:N311	6.835	4	6	8
29	A:A:Y320	6.9075	4	0	7
30	A:A:H322	8.935	4	16	9
31	A:A:K345	6.5875	4	18	5
32	B:B:L14	3.4225	4	0	8
33	B:B:V40	3.41333	6	12	3
34	B:B:H54	8.882	5	8	9
35	B:B:Y59	10.494	5	1	8
36	B:B:W63	7.175	6	0	7
37	B:B:W82	12.148	5	8	9
38	B:B:Y85	11.9275	4	4	4
39	B:B:K89	7.29167	6	8	9
40	B:B:L95	5.472	5	13	8
41	B:B:W99	7.265	8	1	9
42	B:B:Y105	4.9775	4	0	6
43	B:B:N119	6.1525	4	1	9
44	B:B:Y124	6.172	5	13	6
45	B:B:V133	5.37	4	13	4
46	B:B:H142	7.246	5	10	9
47	B:B:Y145	4.87143	7	1	8
48	B:B:C149	3.0175	4	0	8
49	B:B:F151	6.3575	4	0	9
50	B:B:L152	5.015	4	0	3
51	B:B:T159	4.615	4	10	9
52	B:B:D163	7.1275	4	10	9
53	B:B:W169	10.134	5	10	8
54	B:B:T173	4.365	4	24	5
55	B:B:F180	7.8475	4	7	7
56	B:B:H183	10.468	5	7	9
57	B:B:R197	7.025	4	2	5
58	B:B:L198	4.215	4	2	3
59	B:B:V200	8.064	5	2	6
60	B:B:K209	9.8975	4	7	6
61	B:B:L210	5.0825	4	2	5
62	B:B:W211	9.15167	6	7	8
63	B:B:D212	5.47167	6	2	9
64	B:B:H225	9.92333	6	2	9
65	B:B:I232	5.064	5	2	8
66	B:B:F234	6.4525	4	2	5
67	B:B:F235	5.838	5	19	6
68	B:B:P236	6.03	4	19	7
69	B:B:F241	8.50667	6	2	6
70	B:B:T243	5.935	4	2	8
71	B:B:S245	6.2375	4	2	9
72	B:B:R251	9.686	5	2	8
73	B:B:F253	7.05333	6	2	6
74	B:B:D254	4.8225	4	0	9
75	B:B:R256	7.595	4	0	9
76	B:B:Y264	4.8175	4	0	5
77	B:B:F278	6.912	5	19	7
78	B:B:Y289	6.87833	6	14	7
79	B:B:N295	5.7875	4	14	6
80	B:B:D298	7.255	4	12	9
81	B:B:L300	5.755	6	12	6
82	B:B:K301	4.868	5	0	5
83	B:B:H311	8.73	4	5	9
84	B:B:M325	4.61286	7	4	5
85	B:B:W332	10.5771	7	1	9
86	B:B:F335	6.08	4	0	4
87	B:B:K337	5.234	5	5	6
88	B:B:W339	6.7725	4	5	9
89	G:G:M38	4.375	4	12	4
90	G:G:D48	6.032	5	25	9
91	G:G:L51	3.5425	4	0	6
92	G:G:N59	5.895	4	4	9
93	G:G:P60	7.52	4	4	9
94	G:G:F61	5.49778	9	4	8
95	R:R:M17	5.32	4	26	7
96	R:R:L47	4.325	4	15	6
97	R:R:I53	3.58	4	0	9
98	R:R:V56	2.895	4	5	7
99	R:R:R60	6.59	5	5	5
100	R:R:M61	6.655	4	5	6
101	R:R:W69	4.98	6	0	7
102	R:R:S76	4.0225	4	28	8
103	R:R:L78	3.575	4	15	8
104	R:R:L84	4.6675	4	0	8
105	R:R:G100	1.725	4	0	8
106	R:R:F103	6.14	4	0	6
107	R:R:K105	3.7325	4	0	7
108	R:R:F112	6.886	5	3	5
109	R:R:N114	4.4375	4	0	8
110	R:R:M115	6.965	4	0	8
111	R:R:Q132	7.23	4	11	7
112	R:R:W156	5.68	4	28	9
113	R:R:Y166	10.188	5	3	4
114	R:R:R170	9.466	5	3	5
115	R:R:D171	4.8025	4	0	5
116	R:R:Y183	8.345	4	26	4
117	R:R:Y184	13.4975	4	3	4
118	R:R:L206	7.4675	4	3	5
119	R:R:K210	7.224	5	3	5
120	R:R:F211	7.72	4	3	6
121	R:R:F215	5.6775	4	3	9
122	R:R:I221	3.7725	4	0	7
123	R:R:R238	6.6525	4	23	3
124	R:R:F244	5.29833	6	0	7
125	R:R:W259	11.1025	4	0	8
126	R:R:Y262	7.0225	4	3	7
127	R:R:H263	6.46	5	3	8
128	R:R:H273	8.4375	4	0	1
129	R:R:R279	3.25	5	0	1
130	R:R:W283	5.3275	4	0	4
131	R:R:F294	8.415	4	0	6
132	R:R:P301	4.0575	4	15	9
133	R:R:Y304	4.35	6	27	9
134	R:R:M311	5.5525	4	0	8
135	R:R:K314	7.085	4	5	4
136	W:W:?1	9.30143	7	11	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:H54	B:B:I58	18.2917	7.95	Yes	No	0	9	9
2	B:B:I58	B:B:S316	18.5047	3.1	No	No	0	9	9
3	B:B:S316	B:B:W332	43.4588	4.94	No	Yes	0	9	9
4	B:B:W332	B:B:Y59	77.3642	22.19	Yes	Yes	1	9	8
5	B:B:Q75	B:B:Y59	85.0597	12.4	No	Yes	1	9	8
6	B:B:Q75	B:B:W99	92.4564	5.48	No	Yes	1	9	9
7	A:A:K35	B:B:W99	50.3049	4.64	No	Yes	1	9	9
8	A:A:K197	A:A:K35	50.2065	4.31	Yes	No	1	6	9
9	A:A:E33	A:A:K197	100	9.45	No	Yes	0	6	6
10	A:A:E33	A:A:H195	99.7834	6.15	No	No	0	6	4
11	A:A:H195	A:A:T190	99.5688	8.21	No	No	0	4	3
12	A:A:H57	A:A:T190	99.3558	4.11	No	No	0	8	3
13	A:A:F189	A:A:H57	99.1509	4.53	No	No	0	9	8
14	A:A:F189	A:A:F196	74.114	16.08	No	Yes	0	9	7
15	A:A:F196	A:A:V339	66.2844	6.55	Yes	No	9	7	8
16	A:A:I343	A:A:V339	66.3006	3.07	No	No	0	7	8
17	A:A:I343	A:A:N347	65.7817	4.25	No	No	0	7	8
18	A:A:N347	R:R:Q132	65.5227	5.28	No	Yes	0	8	7
19	R:R:Q132	R:R:R143	64.7022	11.68	Yes	No	11	7	7
20	R:R:R143	R:R:V65	65.2074	10.46	No	No	0	7	5
21	R:R:V65	R:R:W69	64.9417	3.68	No	Yes	0	5	7
22	R:R:C152	R:R:W69	60.3398	5.22	No	Yes	0	7	7
23	R:R:C152	R:R:H72	60.0698	14.74	No	No	0	7	9
24	A:A:F199	B:B:W99	50.5991	14.03	Yes	Yes	1	5	9
25	A:A:F199	A:A:K197	50.2063	7.44	Yes	Yes	1	5	6
26	A:A:F189	A:A:M198	37.596	3.73	No	Yes	0	9	7
27	A:A:L38	A:A:M198	36.2394	7.07	No	Yes	0	8	7
28	A:A:K46	A:A:L38	35.7188	9.87	Yes	No	0	9	8
29	A:A:N256	A:A:W258	24.862	7.91	No	Yes	0	8	5
30	A:A:F259	A:A:N256	24.316	7.25	Yes	No	0	9	8
31	A:A:F259	A:A:I221	22.3088	8.79	Yes	No	6	9	8
32	A:A:I221	A:A:I264	21.9162	4.42	No	Yes	6	8	6
33	A:A:F250	A:A:I264	15.4978	7.54	No	Yes	0	9	6
34	A:A:F223	A:A:F250	14.7148	13.93	No	No	0	9	9
35	A:A:F223	A:A:L266	14.514	4.87	No	Yes	0	9	9
36	A:A:L266	A:A:L268	12.6452	5.54	Yes	No	0	9	8
37	A:A:L227	A:A:L268	12.2998	6.92	No	No	0	7	8
38	A:A:C224	A:A:K46	30.1013	3.23	No	Yes	20	7	9
39	A:A:C224	A:A:N269	31.0509	3.15	No	Yes	0	7	9
40	B:B:L117	B:B:W99	89.4727	6.83	No	Yes	1	9	9
41	B:B:L117	B:B:Y145	89.3993	3.52	No	Yes	1	9	8
42	B:B:M188	B:B:Y145	58.6857	4.79	No	Yes	0	8	8
43	A:A:K210	B:B:M188	57.5287	5.76	No	No	0	9	8
44	A:A:K210	B:B:N230	57.3675	11.19	No	No	0	9	9
45	A:A:N269	A:A:T324	28.7887	8.77	Yes	No	0	9	9
46	A:A:F267	A:A:T324	27.3288	3.89	Yes	No	0	9	9
47	A:A:F267	A:A:I265	25.3294	6.28	Yes	Yes	16	9	8
48	B:B:R314	B:B:W332	36.2036	7	No	Yes	1	8	9
49	A:A:I265	A:A:Y320	24.4792	3.63	Yes	Yes	0	8	7
50	A:A:E318	A:A:Y320	10.2091	15.71	No	Yes	0	4	7
51	A:A:D341	A:A:Y320	10.5096	5.75	No	Yes	0	8	7
52	R:R:L233	R:R:R238	18.6414	4.86	No	Yes	0	8	3
53	R:R:L233	R:R:R240	18.044	8.5	No	No	0	8	5
54	R:R:F244	R:R:R240	15.652	4.28	Yes	No	0	7	5
55	B:B:D246	B:B:N230	57.208	13.46	No	No	0	9	9
56	B:B:D246	B:B:S227	57.0496	2.94	No	No	0	9	6
57	B:B:S227	B:B:S245	56.7351	3.26	No	Yes	0	6	9
58	B:B:H225	B:B:S245	41.6697	9.76	Yes	Yes	2	9	9
59	B:B:F253	B:B:H225	27.4478	4.53	Yes	Yes	2	6	9
60	B:B:M325	G:G:P49	19.2649	5.03	Yes	No	0	5	7
61	G:G:D48	G:G:P49	18.1314	3.22	Yes	No	0	9	7
62	G:G:D48	G:G:L51	16.6195	8.14	Yes	Yes	0	9	6
63	B:B:V40	G:G:L51	15.1359	2.98	Yes	Yes	0	3	6
64	B:B:M325	G:G:F61	10.6772	3.73	Yes	Yes	4	5	8
65	B:B:D290	B:B:R314	38.4451	23.82	No	No	0	6	8
66	B:B:C271	B:B:D290	11.7052	6.22	No	No	0	5	6
67	B:B:C271	B:B:D291	11.2683	4.67	No	No	0	5	8
68	B:B:D291	B:B:Y289	10.8304	3.45	No	Yes	0	8	7
69	B:B:D290	B:B:T274	29.0975	4.34	No	No	0	6	8
70	B:B:S275	B:B:T274	28.368	3.2	No	No	0	8	8
71	B:B:L318	B:B:S275	28.1864	9.01	No	No	0	6	8
72	B:B:L318	B:B:T329	26.7522	2.95	No	No	0	6	8
73	B:B:T329	B:B:W339	12.4218	3.64	No	Yes	0	8	9
74	B:B:H311	B:B:T329	14.1352	8.21	Yes	No	0	9	8
75	B:B:H311	B:B:K337	11.5806	7.86	Yes	Yes	5	9	6
76	B:B:K337	B:B:W339	11.5917	4.64	Yes	Yes	5	6	9
77	B:B:K337	R:R:R60	21.9158	7.43	Yes	Yes	5	6	5
78	B:B:S84	B:B:W63	13.9154	4.94	No	Yes	0	5	7
79	B:B:M61	B:B:W63	25.8556	3.49	No	Yes	0	6	7
80	B:B:C317	B:B:S316	26.2488	3.44	No	No	0	7	9
81	B:B:T321	B:B:W63	11.1883	9.7	No	Yes	0	7	7
82	B:B:D323	B:B:M325	10.3774	4.16	No	Yes	4	7	5
83	B:B:M101	B:B:Y145	32.5851	3.59	No	Yes	0	9	8
84	B:B:G116	B:B:M101	32.3754	3.49	No	No	0	9	9
85	B:B:G115	B:B:G116	32.1683	2.11	No	No	0	9	9
86	B:B:G115	B:B:L146	31.9624	3.42	No	No	0	9	7
87	B:B:H142	B:B:L146	31.7578	3.86	Yes	No	0	9	7
88	B:B:H142	B:B:T159	29.1981	6.85	Yes	Yes	10	9	9
89	B:B:C149	B:B:T159	19.3868	3.38	Yes	Yes	0	8	9
90	B:B:A113	B:B:F151	18.5583	4.16	No	Yes	0	9	9
91	B:B:F151	B:B:I157	25.2198	8.79	Yes	No	0	9	7
92	B:B:I157	B:B:I171	24.5837	1.47	No	No	0	7	6
93	B:B:I123	B:B:I171	23.953	1.47	No	No	0	6	6
94	B:B:I123	B:B:S136	23.3274	6.19	No	No	0	6	4
95	B:B:R137	B:B:S136	15.9287	3.95	No	No	0	5	4
96	B:B:G174	B:B:R137	15.337	3	No	No	0	4	5
97	B:B:H225	B:B:T243	13.0526	10.95	Yes	Yes	2	9	8
98	B:B:I232	B:B:T243	25.6846	4.56	Yes	Yes	2	8	8
99	B:B:I232	B:B:V200	22.4011	4.61	Yes	Yes	2	8	6
100	B:B:L210	B:B:V200	30.4537	5.96	Yes	Yes	2	5	6
101	B:B:L198	B:B:L210	20.8749	4.15	Yes	Yes	2	3	5
102	B:B:D212	B:B:L198	18.3949	5.43	Yes	Yes	2	9	3
103	B:B:D212	B:B:V213	30.2338	2.92	Yes	No	0	9	4
104	B:B:L152	B:B:V213	28.5953	2.98	Yes	No	0	3	4
105	B:B:L152	B:B:L192	20.4176	4.15	Yes	No	0	3	5
106	B:B:L192	B:B:R150	18.7861	6.07	No	No	0	5	6
107	B:B:C148	B:B:R150	17.1646	4.18	No	No	0	6	6
108	B:B:I229	B:B:S245	13.232	3.1	No	Yes	2	7	9
109	B:B:I229	B:B:T243	13.0396	3.04	No	Yes	2	7	8
110	B:B:F241	B:B:F253	22.2656	8.57	Yes	Yes	2	6	6
111	B:B:F241	B:B:V200	11.7078	18.35	Yes	Yes	2	6	6
112	B:B:F241	B:B:L255	10.6516	3.65	Yes	No	0	6	6
113	B:B:L210	B:B:L255	10.4561	4.15	Yes	No	0	5	6
114	B:B:L210	B:B:R219	19.2176	6.07	Yes	No	2	5	5
115	B:B:D212	B:B:R219	18.3953	5.96	Yes	No	2	9	5
116	B:B:C148	B:B:L190	15.5507	4.76	No	No	0	6	5
117	B:B:G174	B:B:T173	14.7542	1.82	No	Yes	0	4	5
118	B:B:L190	B:B:S160	13.938	7.51	No	No	0	5	6
119	B:B:S160	B:B:V187	10.7018	8.08	No	No	7	6	9
120	B:B:D170	B:B:T173	12.3819	4.34	No	Yes	24	9	5
121	B:B:D170	B:B:T177	11.8703	11.56	No	No	0	9	4
122	B:B:T177	B:B:T178	11.2965	4.71	No	No	0	4	4
123	B:B:F180	B:B:T178	10.7238	7.78	Yes	No	0	7	4
124	R:R:H72	R:R:W156	57.9047	3.17	No	Yes	0	9	9
125	R:R:S76	R:R:W156	56.5261	4.94	Yes	Yes	28	8	9
126	R:R:N114	R:R:S76	56.5729	4.47	Yes	Yes	0	8	8
127	R:R:I110	R:R:N114	55.4743	5.66	No	Yes	0	5	8
128	R:R:I110	R:R:S83	54.9235	9.29	No	No	0	5	6
129	R:R:L84	R:R:S83	54.6476	3	Yes	No	0	8	6
130	R:R:H107	R:R:L84	33.167	3.86	No	Yes	0	5	8
131	R:R:C182	R:R:H107	32.8757	10.32	No	No	0	9	5
132	R:R:C182	R:R:R170	28.3766	5.57	No	Yes	3	9	5
133	R:R:K105	R:R:R170	23.8104	4.95	Yes	Yes	0	7	5
134	R:R:K105	R:R:T101	22.5608	3	Yes	No	0	7	4
135	R:R:D171	R:R:T101	22.2477	4.34	Yes	No	0	5	4
136	R:R:D171	R:R:N185	11.6186	6.73	Yes	No	0	5	4
137	R:R:D171	R:R:L14	10.0051	4.07	Yes	No	0	5	7
138	R:R:M17	R:R:Y183	13.5757	8.38	Yes	Yes	26	7	4
139	R:R:M17	R:R:W283	10.3796	5.82	Yes	Yes	0	7	4
140	R:R:F294	R:R:L84	20.5319	8.53	Yes	Yes	0	6	8
141	R:R:R60	R:R:V56	12.0859	3.92	Yes	Yes	5	5	7
142	R:R:L315	R:R:V56	10.4205	1.49	No	Yes	0	5	7
143	R:R:F111	R:R:F294	18.7657	7.5	No	Yes	0	6	6
144	R:R:F111	R:R:Y262	11.1678	10.32	No	Yes	3	6	7
145	R:R:H263	R:R:Y262	10.0568	5.44	Yes	Yes	3	8	7
146	B:B:C317	B:B:M61	26.0501	4.86	No	No	0	7	6
147	B:B:D323	B:B:T321	10.5413	8.67	No	No	4	7	7
148	B:B:S84	G:G:F61	12.2357	5.28	No	Yes	4	5	8
149	A:A:H213	A:A:W258	14.0459	8.46	Yes	Yes	1	8	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I221	R:R:L127	4.28	0	Yes	No	7	6	2	1
R:R:L127	W:W:?1	6.2	0	No	Yes	6	0	1	0
R:R:D128	R:R:Q132	10.44	11	No	Yes	8	7	1	2
R:R:D128	R:R:R143	7.15	11	No	No	8	7	1	2
R:R:D128	W:W:?1	6.08	11	No	Yes	8	0	1	0
R:R:Q132	R:R:R143	11.68	11	Yes	No	7	7	2	2
R:R:H142	R:R:W138	21.16	11	No	No	4	4	1	1
R:R:W138	W:W:?1	8.5	11	No	Yes	4	0	1	0
R:R:H142	R:R:N141	6.38	11	No	No	4	5	1	2
R:R:H142	W:W:?1	27.83	11	No	Yes	4	0	1	0
R:R:A147	W:W:?1	7.06	0	No	Yes	3	0	1	0
R:R:K150	W:W:?1	7.37	0	No	Yes	2	0	1	0
R:R:L131	W:W:?1	2.07	0	No	Yes	6	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
50.00	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
50.00	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
50.00	Single	9CM3	Compound 187	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
46.15	Single	9IYB	A1D5Q	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
45.45	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
44.44	Single	9NS9	Compound 187	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
42.86	Single	8XXV	A1D5Q	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
41.67	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
35.71	Single	8YYX	Leukotriene e4	8YYX-Oxoglutarate-Leukotriene e4-chim(Gi1-CtGq)/β1/γ2
26.67	Single	9CM7	AZ-1729	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
25.00	Single	5KW2	PubChem 133053953	5KW2-FFA1-PubChem 133053953
25.00	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
25.00	Single	9K1C	DHA	9K1C-FFA1-DHA-Gi1/β1/γ2
23.08	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/β1/γ2
20.00	Single	5XSZ	Glyceryl-mono-oleate	5XSZ-LPA₆-Glyceryl-mono-oleate
17.65	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/β1/γ2
15.38	Single	8K9L	BMS-986122	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
14.29	Single	8Y72	BMS-986122	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
14.29	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
13.33	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
9.52	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
7.69	Single	6OBA	GTPL11074	6OBA-β₂-S-Alprenolol-GTPL11074
7.14	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
7.14	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	9JCQ	LPC	9JCQ-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
5.88	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
5.56	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/β1/γ2

PDB Summary
PDB	8XXU
Class	A
SubFamily	Lipid
Type	Prostanoid
SubType	DP2
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	A1D5Q
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	2.54
Date	2024-12-04
D.O.I.	doi.org/10.1073/pnas.2403304121

Net Summary
I_min	3
Number of Linked Nodes	866
Number of Links	991
Number of Hubs	136
Number of Links mediated by Hubs	520
Number of Communities	28
Number of Nodes involved in Communities	197
Number of Links involved in Communities	267

Path Summary
Number Of Nodes in MetaPath	150
Number Of Links MetaPath	149
Number of Shortest Paths	1335563
Length Of Smallest Path	3
Average Path Length	34.2489
Length of Longest Path	65
Minimum Path Strength	1.27
Average Path Strength	6.65601
Maximum Path Strength	20.93
Minimum Path Correlation	0.7
Average Path Correlation	0.982075
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.96078
Average % Of Corr. Nodes	40.6078
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.8242
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_W_
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	_W_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8XXU_Chain_A T L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K T I V K Q M K I I H T T G I V E T H F T F K D L H F K M F D V G Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E M N R M H S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C T D T K N V Q F V F D A V T D V I I K N N L K D C G L F N A A S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8XXU_Chain_B L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8XXU_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R E K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q9Y5Y4
Sequence	>8XXU_Chain_R L C P I L E Q M S R L Q S H S N T S I R Y I D H A A V L L H G L A S L L G L V E N G V I L F V V G C R M R Q T V V T T W V L H L A L S D L L A S A S L P F F T Y F L A V G H S W E L G T T F C K L H S S I F F L N M F A S G F L L S A I S L D R C L Q V V R P V W A Q N H R T V A A A H K V C L V L W A L A V L N T V P Y F V F R D T I S D G R I M C Y Y N V L L L N P G P D R D A T C N S R Q V A L A V S K F L L A F L V P L A I I A S S H A A V S L R L Q H R G R R R P G R F V R L V A A V V A A F A L C W G P Y H V F S L L E A R A H A N P G L R P L V W R G L P F V T S L A F F N S V A N P V L Y V L T C P D M L R K L R R S L R T V L E S V L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7M8W	A	Lipid	Prostanoid	DP₂	Homo sapiens	15r-Methyl-Prostaglandin D2	Na	-	2.61	2021-08-25	doi.org/10.1073/pnas.2102813118
	9IYB	A	Lipid	Prostanoid	DP₂	Homo sapiens	Prostaglandin	A1D5Q	Gi1/β1/γ2	2.82	2024-12-04	doi.org/10.1073/pnas.2403304121
	9IYB (No Gprot)	A	Lipid	Prostanoid	DP₂	Homo sapiens	Prostaglandin	A1D5Q		2.82	2024-12-04	doi.org/10.1073/pnas.2403304121
	8XXU (No Gprot)	A	Lipid	Prostanoid	DP₂	Homo sapiens	-	A1D5Q		2.54	2024-12-04	doi.org/10.1073/pnas.2403304121
	8XXV	A	Lipid	Prostanoid	DP₂	Homo sapiens	Indomethacin	A1D5Q	Gi1/β1/γ2	2.33	2024-12-04	doi.org/10.1073/pnas.2403304121
	8XXV (No Gprot)	A	Lipid	Prostanoid	DP₂	Homo sapiens	Indomethacin	A1D5Q		2.33	2024-12-04	doi.org/10.1073/pnas.2403304121
	6D26	A	Lipid	Prostanoid	DP₂	Homo sapiens	Fevipiprant	-	-	2.8	2018-10-03	doi.org/10.1016/j.molcel.2018.08.009
	6D27	A	Lipid	Prostanoid	DP₂	Homo sapiens	CAY10471	-	-	2.74	2018-10-03	doi.org/10.1016/j.molcel.2018.08.009

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XXU.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.