psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:A12	B:B:N88	3.13	No	No	0	4	7
2	A:A:I19	A:A:R15	3.76	No	No	0	9	5
3	A:A:R15	B:B:H91	3.39	No	Yes	0	5	5
4	A:A:D20	A:A:S16	2.94	No	No	4	6	7
5	A:A:S16	B:B:N88	5.96	No	No	0	7	7
6	A:A:S16	B:B:K89	3.06	No	Yes	4	7	9
7	A:A:M18	A:A:N22	4.21	No	No	0	4	4
8	A:A:I19	B:B:K89	7.27	No	Yes	0	9	9
9	A:A:I19	B:B:A92	3.25	No	No	0	9	6
10	A:A:D20	B:B:K89	11.06	No	Yes	4	6	9
11	A:A:R21	A:A:R24	3.2	No	No	0	4	3
12	A:A:L23	B:B:K78	7.05	No	Yes	0	6	8
13	A:A:E28	A:A:R24	4.65	No	No	0	4	3
14	A:A:D26	B:B:K78	5.53	No	Yes	0	5	8
15	A:A:A31	R:R:H692	2.93	No	No	0	4	6
16	A:A:E33	A:A:K35	4.05	No	No	1	6	9
17	A:A:E33	A:A:H195	16	No	No	0	6	4
18	A:A:E33	A:A:K197	22.95	No	Yes	1	6	6
19	A:A:L36	A:A:V34	2.98	Yes	Yes	9	7	5
20	A:A:L194	A:A:V34	4.47	Yes	Yes	9	4	5
21	A:A:F196	A:A:V34	11.8	Yes	Yes	9	7	5
22	A:A:V339	A:A:V34	6.41	Yes	Yes	9	8	5
23	A:A:K197	A:A:K35	2.87	Yes	No	1	6	9
24	A:A:F196	A:A:L36	2.44	Yes	Yes	9	7	7
25	A:A:I222	A:A:L36	7.14	No	Yes	0	7	7
26	A:A:L36	A:A:V339	4.47	Yes	Yes	9	7	8
27	A:A:L37	A:A:L39	4.15	Yes	Yes	1	9	9
28	A:A:L37	A:A:V201	2.98	Yes	Yes	1	9	9
29	A:A:F215	A:A:L37	2.44	Yes	Yes	1	9	9
30	A:A:I221	A:A:L37	2.85	No	Yes	1	8	9
31	A:A:F259	A:A:L37	2.44	Yes	Yes	1	9	9
32	A:A:K46	A:A:L38	5.64	Yes	Yes	6	9	8
33	A:A:L38	A:A:M198	2.83	Yes	Yes	6	8	7
34	A:A:D200	A:A:L38	4.07	No	Yes	6	9	8
35	A:A:I222	A:A:L38	8.56	No	Yes	0	7	8
36	A:A:F223	A:A:L39	2.44	Yes	Yes	1	9	9
37	A:A:L249	A:A:L39	2.77	No	Yes	1	9	9
38	A:A:I253	A:A:L39	5.71	Yes	Yes	1	8	9
39	A:A:G40	A:A:K46	3.49	No	Yes	0	9	9
40	A:A:A41	A:A:S44	3.42	No	No	0	7	9
41	A:A:A41	A:A:R242	4.15	No	Yes	0	7	9
42	A:A:D42	A:A:R242	7.15	No	Yes	0	8	9
43	A:A:K46	A:A:S44	3.06	Yes	No	0	9	9
44	A:A:G45	A:A:N269	5.09	No	Yes	0	9	9
45	A:A:D200	A:A:K46	8.3	No	Yes	6	9	9
46	A:A:C224	A:A:K46	4.85	No	Yes	6	7	9
47	A:A:C224	A:A:I49	4.91	No	Yes	6	7	7
48	A:A:F267	A:A:I49	6.28	Yes	Yes	6	9	7
49	A:A:I49	A:A:N269	8.5	Yes	Yes	6	7	9
50	A:A:I49	A:A:N331	2.83	Yes	No	6	7	8
51	A:A:T187	A:A:V50	4.76	No	No	6	6	6
52	A:A:M198	A:A:V50	3.04	Yes	No	6	7	6
53	A:A:D328	A:A:Q52	7.83	No	No	0	9	9
54	A:A:G183	A:A:T182	3.64	No	No	0	9	7
55	A:A:G183	A:A:Q204	3.29	No	Yes	1	9	9
56	A:A:G183	B:B:N119	5.09	No	No	1	9	9
57	A:A:I184	A:A:Q204	2.74	Yes	Yes	1	9	9
58	A:A:F215	A:A:I184	2.51	Yes	Yes	1	9	9
59	A:A:I184	B:B:W99	5.87	Yes	Yes	1	9	9
60	A:A:I184	B:B:L117	2.85	Yes	Yes	1	9	9
61	A:A:E186	A:A:H188	3.69	No	No	0	9	3
62	A:A:E186	A:A:F199	10.49	No	Yes	1	9	5
63	A:A:E186	B:B:W99	6.54	No	Yes	1	9	9
64	A:A:M198	A:A:T187	3.01	Yes	No	6	7	6
65	A:A:H188	A:A:H195	5.97	No	No	0	3	4
66	A:A:H188	A:A:K197	10.48	No	Yes	0	3	6
67	A:A:F189	A:A:F196	16.08	No	Yes	0	9	7
68	A:A:F189	A:A:M198	4.98	No	Yes	0	9	7
69	A:A:H195	A:A:T190	9.58	No	No	0	4	3
70	A:A:F191	A:A:K192	14.89	Yes	No	9	5	4
71	A:A:A332	A:A:F191	6.93	No	Yes	0	7	5
72	A:A:F191	A:A:Q333	7.03	Yes	No	9	5	5
73	A:A:F191	A:A:F336	6.43	Yes	Yes	9	5	8
74	A:A:K192	A:A:Q333	8.14	No	No	9	4	5
75	A:A:F336	A:A:K192	9.93	Yes	No	9	8	4
76	A:A:F196	A:A:L194	8.53	Yes	Yes	9	7	4
77	A:A:F336	A:A:L194	4.87	Yes	Yes	9	8	4
78	A:A:L194	R:R:F690	12.18	Yes	Yes	9	4	8
79	A:A:F196	A:A:V339	5.24	Yes	Yes	9	7	8
80	A:A:F199	A:A:K197	3.72	Yes	Yes	1	5	6
81	A:A:F199	A:A:F215	6.43	Yes	Yes	1	5	9
82	A:A:F199	B:B:W99	11.02	Yes	Yes	1	5	9
83	A:A:V201	A:A:W211	3.68	Yes	Yes	1	9	9
84	A:A:F215	A:A:V201	5.24	Yes	Yes	1	9	9
85	A:A:Q204	A:A:S206	5.78	Yes	No	1	9	8
86	A:A:Q204	A:A:W211	7.67	Yes	Yes	1	9	9
87	A:A:Q204	B:B:L117	7.99	Yes	Yes	1	9	9
88	A:A:Q204	B:B:N119	6.6	Yes	No	1	9	9
89	A:A:Q204	B:B:Y145	4.51	Yes	Yes	1	9	8
90	A:A:S206	A:A:W211	6.18	No	Yes	1	8	9
91	A:A:S206	B:B:Y145	5.09	No	Yes	1	8	8
92	A:A:E207	A:A:K209	8.1	Yes	No	1	9	8
93	A:A:E207	A:A:K210	5.4	Yes	Yes	1	9	9
94	A:A:E207	B:B:D186	7.8	Yes	No	1	9	9
95	A:A:E207	B:B:C204	3.04	Yes	Yes	1	9	7
96	A:A:E207	B:B:D228	2.6	Yes	Yes	1	9	9
97	A:A:K209	A:A:K210	2.87	No	Yes	1	8	9
98	A:A:K209	B:B:D228	5.53	No	Yes	1	8	9
99	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
100	A:A:K210	B:B:M188	10.08	Yes	Yes	1	9	8
101	A:A:K210	B:B:C204	4.85	Yes	Yes	1	9	7
102	A:A:K210	B:B:D228	8.3	Yes	Yes	1	9	9
103	A:A:K210	B:B:N230	5.6	Yes	No	1	9	9
104	A:A:K210	B:B:D246	4.15	Yes	No	1	9	9
105	A:A:F215	A:A:W211	4.01	Yes	Yes	1	9	9
106	A:A:W211	B:B:L117	5.69	Yes	Yes	1	9	9
107	A:A:W211	B:B:Y145	5.79	Yes	Yes	1	9	8
108	A:A:F215	A:A:I212	3.77	Yes	No	0	9	8
109	A:A:F259	A:A:I212	5.02	Yes	No	0	9	8
110	A:A:H213	A:A:W258	7.41	No	Yes	2	8	5
111	A:A:H213	B:B:Y59	7.62	No	Yes	2	8	8
112	A:A:H213	B:B:W332	9.52	No	Yes	2	8	9
113	A:A:C214	A:A:F215	2.79	No	Yes	0	7	9
114	A:A:C214	B:B:Q75	4.58	No	Yes	0	7	9
115	A:A:F215	B:B:W99	5.01	Yes	Yes	1	9	9
116	A:A:F215	B:B:L117	2.44	Yes	Yes	1	9	9
117	A:A:E216	A:A:W258	5.45	No	Yes	0	7	5
118	A:A:E216	B:B:K57	8.1	No	No	0	7	9
119	A:A:T262	A:A:V218	3.17	No	No	0	7	9
120	A:A:A220	A:A:I265	3.25	No	Yes	0	8	8
121	A:A:F259	A:A:I221	8.79	Yes	No	1	9	8
122	A:A:I221	A:A:T262	6.08	No	No	1	8	7
123	A:A:I222	A:A:I265	5.89	No	Yes	0	7	8
124	A:A:F223	A:A:V225	2.62	Yes	No	1	9	7
125	A:A:F223	A:A:F250	5.36	Yes	Yes	1	9	9
126	A:A:F223	A:A:L266	2.44	Yes	Yes	1	9	9
127	A:A:C224	A:A:N269	4.72	No	Yes	6	7	9
128	A:A:M243	A:A:V225	3.04	No	No	1	8	7
129	A:A:F307	A:A:V225	7.87	Yes	No	1	8	7
130	A:A:D226	A:A:S228	2.94	No	No	11	8	9
131	A:A:D226	A:A:D229	14.64	No	No	11	8	8
132	A:A:D226	A:A:K270	15.21	No	No	11	8	9
133	A:A:L227	A:A:L268	9.69	No	No	0	7	8
134	A:A:F274	A:A:L227	15.83	Yes	No	0	9	7
135	A:A:I303	A:A:L227	4.28	No	No	0	7	7
136	A:A:K270	A:A:S228	4.59	No	No	11	9	9
137	A:A:L273	A:A:S228	9.01	No	No	0	6	9
138	A:A:D229	A:A:N241	4.04	No	No	11	8	9
139	A:A:D229	A:A:R242	4.76	No	Yes	11	8	9
140	A:A:F274	A:A:Y230	7.22	Yes	Yes	1	9	8
141	A:A:K277	A:A:Y230	16.72	No	Yes	1	9	8
142	A:A:L283	A:A:Y230	4.69	No	Yes	1	7	8
143	A:A:C286	A:A:Y230	13.44	No	Yes	0	6	8
144	A:A:Y230	A:A:Y287	5.96	Yes	No	1	8	7
145	A:A:N241	A:A:R242	6.03	No	Yes	11	9	9
146	A:A:E245	A:A:R242	16.28	No	Yes	0	9	9
147	A:A:M243	A:A:Y287	5.99	No	No	1	8	7
148	A:A:F307	A:A:M243	2.49	Yes	No	1	8	8
149	A:A:M247	A:A:Q306	2.72	No	No	0	6	5
150	A:A:F307	A:A:M247	3.73	Yes	No	0	8	6
151	A:A:L310	A:A:M247	4.24	No	No	0	4	6
152	A:A:I253	A:A:L249	2.85	Yes	No	1	8	9
153	A:A:F250	A:A:I264	6.28	Yes	Yes	1	9	6
154	A:A:F250	A:A:L266	3.65	Yes	Yes	1	9	9
155	A:A:F250	A:A:L310	4.87	Yes	No	0	9	4
156	A:A:D251	A:A:N255	6.73	No	No	0	5	8
157	A:A:D251	A:A:L310	4.07	No	No	0	5	4
158	A:A:I253	A:A:N256	4.25	Yes	No	0	8	8
159	A:A:F259	A:A:I253	2.51	Yes	Yes	1	9	8
160	A:A:C254	A:A:N255	4.72	No	No	0	5	8
161	A:A:C254	A:A:N311	4.72	No	No	1	5	8
162	A:A:C254	A:A:K317	3.23	No	Yes	1	5	7
163	A:A:K312	A:A:N255	13.99	No	No	0	5	8
164	A:A:K257	A:A:W258	8.12	No	Yes	0	4	5
165	A:A:W258	B:B:R314	5	Yes	Yes	2	5	8
166	A:A:W258	B:B:W332	2.81	Yes	Yes	2	5	9
167	A:A:F259	A:A:T262	7.78	Yes	No	1	9	7
168	A:A:D261	A:A:T260	8.67	No	No	0	4	3
169	A:A:R313	A:A:T260	10.35	Yes	No	0	4	3
170	A:A:D261	A:A:T316	4.34	No	No	0	4	3
171	A:A:D261	A:A:K349	2.77	No	No	0	4	5
172	A:A:S263	A:A:Y320	2.54	No	Yes	6	7	7
173	A:A:S263	A:A:V342	6.46	No	No	6	7	7
174	A:A:I264	A:A:L266	4.28	Yes	Yes	1	6	9
175	A:A:I264	A:A:K317	5.82	Yes	Yes	1	6	7
176	A:A:I264	A:A:I319	5.89	Yes	No	1	6	5
177	A:A:I265	A:A:Y320	4.84	Yes	Yes	6	8	7
178	A:A:F334	A:A:I265	3.77	Yes	Yes	6	3	8
179	A:A:A338	A:A:I265	4.87	No	Yes	6	6	8
180	A:A:L266	A:A:T321	4.42	Yes	No	0	9	5
181	A:A:F267	A:A:H322	6.79	Yes	Yes	6	9	9
182	A:A:F267	A:A:N331	4.83	Yes	No	6	9	8
183	A:A:F267	A:A:F334	5.36	Yes	Yes	6	9	3
184	A:A:F267	A:A:I335	3.77	Yes	No	0	9	8
185	A:A:F307	A:A:L268	2.44	Yes	No	0	8	8
186	A:A:F323	A:A:L268	6.09	Yes	No	0	4	8
187	A:A:N269	A:A:T324	5.85	Yes	No	0	9	9
188	A:A:K271	A:A:Y296	3.58	No	No	0	5	4
189	A:A:F323	A:A:K271	4.96	Yes	No	0	4	5
190	A:A:K271	A:A:T324	3	No	No	0	5	9
191	A:A:D272	A:A:L273	4.07	No	No	0	9	6
192	A:A:E276	A:A:L273	6.63	No	No	0	5	6
193	A:A:F274	A:A:K277	2.48	Yes	No	1	9	9
194	A:A:F274	A:A:I278	12.56	Yes	No	0	9	6
195	A:A:F274	A:A:Y296	8.25	Yes	No	0	9	4
196	A:A:E275	A:A:Y296	24.69	No	No	0	5	4
197	A:A:E276	A:A:K277	2.7	No	No	0	5	9
198	A:A:E276	A:A:K280	4.05	No	No	0	5	1
199	A:A:P282	A:A:S281	3.56	No	No	0	5	7
200	A:A:I285	A:A:P282	3.39	No	No	0	3	5
201	A:A:L283	A:A:Y287	3.52	No	No	1	7	7
202	A:A:A291	A:A:L283	4.73	No	No	0	3	7
203	A:A:A291	A:A:T284	3.36	No	No	0	3	4
204	A:A:C286	A:A:I285	3.27	No	No	0	6	3
205	A:A:G292	A:A:Y290	2.9	No	No	0	7	7
206	A:A:Y290	A:A:Y302	8.94	No	No	0	7	6
207	A:A:S293	A:A:T295	6.4	No	No	13	3	5
208	A:A:E298	A:A:S293	5.75	No	No	13	4	3
209	A:A:E298	A:A:T295	5.64	No	No	13	4	5
210	A:A:E297	A:A:E298	2.54	No	No	0	4	4
211	A:A:A300	A:A:F323	2.77	No	Yes	0	5	4
212	A:A:Q306	A:A:Y302	15.78	No	No	0	5	6
213	A:A:I303	A:A:Q306	6.86	No	No	0	7	5
214	A:A:F307	A:A:I303	5.02	Yes	No	0	8	7
215	A:A:Q304	A:A:T321	9.92	No	No	0	5	5
216	A:A:F323	A:A:Q304	4.68	Yes	No	0	4	5
217	A:A:E308	A:A:I319	6.83	No	No	1	3	5
218	A:A:E308	R:R:R780	5.82	No	Yes	1	3	3
219	A:A:K317	A:A:N311	18.19	Yes	No	1	7	8
220	A:A:K312	A:A:R313	3.71	No	Yes	0	5	4
221	A:A:R313	A:A:T316	2.59	Yes	No	0	4	3
222	A:A:K317	A:A:R313	3.71	Yes	Yes	0	7	4
223	A:A:K314	R:R:R780	7.43	No	Yes	0	3	3
224	A:A:E318	A:A:Y320	7.86	No	Yes	0	4	7
225	A:A:E318	R:R:R777	8.14	No	Yes	0	4	5
226	A:A:I319	R:R:R780	5.01	No	Yes	1	5	3
227	A:A:A338	A:A:Y320	2.67	No	Yes	6	6	7
228	A:A:D341	A:A:Y320	5.75	No	Yes	0	8	7
229	A:A:V342	A:A:Y320	5.05	No	Yes	6	7	7
230	A:A:Y320	R:R:V774	5.05	Yes	No	0	7	5
231	A:A:T321	R:R:R777	2.59	No	Yes	0	5	5
232	A:A:C325	A:A:H322	2.95	No	Yes	0	7	9
233	A:A:H322	A:A:N331	2.55	Yes	No	6	9	8
234	A:A:F334	A:A:H322	21.5	Yes	Yes	6	3	9
235	A:A:F323	R:R:E776	9.33	Yes	No	0	4	5
236	A:A:C325	A:A:K330	8.08	No	No	0	7	4
237	A:A:T327	A:A:T329	7.85	No	No	0	8	9
238	A:A:D337	A:A:Q333	7.83	No	No	0	4	5
239	A:A:F334	R:R:V774	2.62	Yes	No	0	3	5
240	A:A:F334	R:R:G775	3.01	Yes	No	0	3	6
241	A:A:F336	R:R:F690	3.22	Yes	Yes	9	8	8
242	A:A:V339	R:R:F690	2.62	Yes	Yes	9	8	8
243	A:A:T340	R:R:V689	6.35	No	Yes	9	6	9
244	A:A:T340	R:R:F690	6.49	No	Yes	9	6	8
245	A:A:D341	A:A:K345	9.68	No	No	0	8	5
246	A:A:I343	A:A:N347	2.83	No	No	0	7	8
247	A:A:I343	R:R:V689	3.07	No	Yes	9	7	9
248	A:A:I343	R:R:F690	6.28	No	Yes	9	7	8
249	A:A:I344	R:R:V689	4.61	No	Yes	0	6	9
250	A:A:F354	A:A:K345	4.96	Yes	No	0	5	5
251	A:A:K349	A:A:N346	2.8	No	No	0	5	4
252	A:A:N347	R:R:R685	8.44	No	Yes	0	8	8
253	A:A:F354	A:A:L348	8.53	Yes	No	0	5	9
254	A:A:L348	R:R:I686	5.71	No	No	0	9	7
255	A:A:F354	A:A:K349	2.48	Yes	No	0	5	5
256	A:A:D350	R:R:T619	2.89	No	No	0	4	8
257	A:A:C351	R:R:L682	3.17	No	No	0	4	9
258	A:A:C351	R:R:R685	2.79	No	Yes	0	4	8
259	A:A:L353	R:R:L682	2.77	No	No	0	7	9
260	A:A:L353	R:R:V765	2.98	No	No	0	7	9
261	A:A:L353	R:R:S792	6.01	No	No	0	7	8
262	A:A:F354	R:R:L769	2.44	Yes	No	0	5	7
263	A:A:F354	R:R:R788	12.83	Yes	No	0	5	7
264	A:A:F354	R:R:K791	3.72	Yes	No	0	5	8
265	B:B:E3	B:B:Q6	5.1	No	No	14	5	1
266	B:B:E3	B:B:L7	2.65	No	Yes	14	5	8
267	B:B:L4	B:B:R8	7.29	No	No	0	4	3
268	B:B:L7	B:B:Q6	5.32	Yes	No	14	8	1
269	B:B:L7	G:G:A12	3.15	Yes	No	0	8	5
270	B:B:E10	B:B:Q13	12.74	No	No	15	8	1
271	B:B:E10	B:B:L14	3.98	No	Yes	15	8	8
272	B:B:E10	G:G:V16	2.85	No	No	0	8	7
273	B:B:E12	B:B:N16	7.89	No	No	0	4	1
274	B:B:L14	B:B:Q13	6.65	Yes	No	15	8	1
275	B:B:L14	G:G:L19	4.15	Yes	No	0	8	9
276	B:B:N16	B:B:R19	12.05	No	No	0	1	4
277	B:B:I18	B:B:R22	5.01	No	No	0	7	6
278	B:B:I18	G:G:R27	5.01	No	No	0	7	8
279	B:B:D20	B:B:R19	3.57	No	No	16	2	4
280	B:B:K23	B:B:R19	3.71	No	No	16	2	4
281	B:B:D20	B:B:K23	5.53	No	No	16	2	2
282	B:B:D258	B:B:R22	13.1	Yes	No	0	7	6
283	B:B:Q259	B:B:R22	7.01	No	No	0	6	6
284	B:B:C25	G:G:R27	2.79	No	No	0	3	8
285	B:B:D27	G:G:K29	5.53	Yes	No	0	8	4
286	B:B:D27	G:G:V30	2.92	Yes	No	0	8	8
287	B:B:D27	G:G:S31	7.36	Yes	No	0	8	9
288	B:B:S31	B:B:T29	3.2	No	No	0	1	3
289	B:B:Q32	B:B:T29	5.67	No	No	0	1	3
290	B:B:L30	B:B:T34	2.95	Yes	No	0	5	5
291	B:B:L261	B:B:L30	4.15	No	Yes	0	5	5
292	B:B:L30	B:B:M262	4.24	Yes	No	0	5	4
293	B:B:M262	B:B:S31	4.6	No	No	0	4	1
294	B:B:N35	B:B:N36	10.9	No	No	0	1	1
295	B:B:I37	B:B:R283	8.77	Yes	Yes	2	2	9
296	B:B:I37	B:B:K301	5.82	Yes	Yes	0	2	5
297	B:B:I37	G:G:M38	4.37	Yes	No	2	2	4
298	B:B:I37	G:G:E42	4.1	Yes	No	2	2	1
299	B:B:K301	B:B:P39	6.69	Yes	No	0	5	1
300	B:B:R283	B:B:V40	6.54	Yes	Yes	2	9	3
301	B:B:D298	B:B:V40	8.76	No	Yes	2	9	3
302	B:B:V40	G:G:L51	2.98	Yes	Yes	2	3	6
303	B:B:G306	B:B:R42	4.5	No	No	0	4	2
304	B:B:I43	B:B:M45	5.83	No	Yes	0	3	4
305	B:B:Q44	B:B:R46	3.5	No	No	0	4	5
306	B:B:L308	B:B:M45	8.48	No	Yes	0	7	4
307	B:B:M45	B:B:N340	4.21	Yes	Yes	0	4	9
308	B:B:M45	G:G:L50	2.83	Yes	No	0	4	9
309	B:B:R46	B:B:R48	12.79	No	No	0	5	7
310	B:B:T47	B:B:T50	3.14	No	Yes	2	3	3
311	B:B:K337	B:B:T47	7.51	Yes	No	2	6	3
312	B:B:T47	B:B:W339	9.7	No	Yes	2	3	9
313	B:B:N340	B:B:R48	8.44	Yes	No	0	9	7
314	B:B:R48	G:G:R62	4.26	No	No	0	7	7
315	B:B:R49	B:B:T87	5.17	No	No	0	7	5
316	B:B:I338	B:B:R49	5.01	No	No	4	5	7
317	B:B:R49	G:G:F61	7.48	No	Yes	4	7	8
318	B:B:R52	B:B:T50	5.17	No	Yes	2	7	3
319	B:B:F335	B:B:T50	2.59	No	Yes	2	4	3
320	B:B:K337	B:B:T50	6.01	Yes	Yes	2	6	3
321	B:B:L51	B:B:L70	2.77	Yes	Yes	4	9	5
322	B:B:L51	B:B:W82	19.36	Yes	Yes	4	9	9
323	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
324	B:B:L336	B:B:L51	11.07	Yes	Yes	4	7	9
325	B:B:I338	B:B:L51	5.71	No	Yes	4	5	9
326	B:B:F335	B:B:R52	7.48	No	No	2	4	7
327	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
328	B:B:H54	B:B:I58	13.26	Yes	No	4	9	9
329	B:B:H54	B:B:S72	2.79	Yes	Yes	4	9	9
330	B:B:H54	B:B:S74	11.16	Yes	No	4	9	9
331	B:B:H54	B:B:I80	15.91	Yes	Yes	4	9	8
332	B:B:D76	B:B:L55	6.79	No	No	0	9	6
333	B:B:K57	B:B:Q75	6.78	No	Yes	0	9	9
334	B:B:K57	B:B:W332	13.92	No	Yes	0	9	9
335	B:B:I58	B:B:S74	3.1	No	No	4	9	9
336	B:B:I58	B:B:L336	5.71	No	Yes	4	9	7
337	B:B:Q75	B:B:Y59	7.89	Yes	Yes	0	9	8
338	B:B:M101	B:B:Y59	9.58	No	Yes	0	9	8
339	B:B:S316	B:B:Y59	5.09	No	Yes	2	9	8
340	B:B:W332	B:B:Y59	3.86	Yes	Yes	2	9	8
341	B:B:L70	B:B:M61	4.24	Yes	No	4	5	6
342	B:B:M61	B:B:S72	4.6	No	Yes	4	6	9
343	B:B:C317	B:B:M61	3.24	No	No	0	7	6
344	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
345	B:B:H62	B:B:R150	14.67	No	No	0	6	6
346	B:B:L70	B:B:W63	9.11	Yes	Yes	0	5	7
347	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
348	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
349	B:B:T321	B:B:W63	10.92	No	Yes	0	7	7
350	B:B:A328	B:B:W63	5.19	No	Yes	0	5	7
351	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
352	B:B:D322	B:B:T65	2.89	No	No	0	1	1
353	B:B:D66	B:B:R68	3.57	No	No	0	8	5
354	B:B:D66	B:B:L69	6.79	No	No	0	8	5
355	B:B:S67	B:B:T321	9.59	No	No	4	5	7
356	B:B:D323	B:B:S67	8.83	No	No	4	7	5
357	B:B:D83	B:B:R68	16.68	No	No	0	8	5
358	B:B:R68	B:B:Y85	14.4	No	Yes	0	5	4
359	B:B:L69	B:B:Y105	5.86	No	Yes	0	5	6
360	B:B:L70	B:B:S72	3	Yes	Yes	4	5	9
361	B:B:L70	B:B:W82	4.56	Yes	Yes	4	5	9
362	B:B:L79	B:B:V71	4.47	Yes	No	10	7	8
363	B:B:C103	B:B:V71	5.12	No	No	10	8	8
364	B:B:V71	B:B:Y105	7.57	No	Yes	10	8	6
365	B:B:S72	B:B:W82	4.94	Yes	Yes	4	9	9
366	B:B:L336	B:B:S72	7.51	Yes	Yes	4	7	9
367	B:B:A73	B:B:V100	5.09	No	No	0	9	9
368	B:B:Q75	B:B:W99	4.38	Yes	Yes	0	9	9
369	B:B:D76	B:B:K78	4.15	No	Yes	0	9	8
370	B:B:G77	B:B:S98	3.71	No	No	0	8	8
371	B:B:I80	B:B:K78	2.91	Yes	Yes	0	8	8
372	B:B:I93	B:B:L79	2.85	Yes	Yes	10	7	7
373	B:B:L79	B:B:L95	4.15	Yes	Yes	10	7	8
374	B:B:C103	B:B:L79	3.17	No	Yes	10	8	7
375	B:B:L79	B:B:V112	2.98	Yes	No	10	7	8
376	B:B:C114	B:B:L79	6.35	No	Yes	10	8	7
377	B:B:I80	B:B:W82	11.74	Yes	Yes	4	8	9
378	B:B:I80	B:B:K89	4.36	Yes	Yes	4	8	9
379	B:B:I81	B:B:V90	4.61	No	No	10	7	5
380	B:B:H91	B:B:I81	3.98	Yes	No	10	5	7
381	B:B:I81	B:B:L126	4.28	No	Yes	10	7	5
382	B:B:K89	B:B:W82	12.76	Yes	Yes	4	9	9
383	B:B:L336	B:B:W82	6.83	Yes	Yes	4	7	9
384	B:B:D83	B:B:T86	5.78	No	No	0	8	6
385	B:B:S84	B:B:Y85	2.54	No	Yes	4	5	4
386	B:B:S84	G:G:F61	5.28	No	Yes	4	5	8
387	B:B:Y85	G:G:P60	11.13	Yes	Yes	4	4	9
388	B:B:Y85	G:G:F61	8.25	Yes	Yes	4	4	8
389	B:B:N88	B:B:T86	10.24	No	No	0	7	6
390	B:B:H91	B:B:V90	5.54	Yes	No	10	5	5
391	B:B:H91	B:B:L126	3.86	Yes	Yes	10	5	5
392	B:B:H91	B:B:V133	5.54	Yes	No	0	5	4
393	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
394	B:B:I93	B:B:L95	2.85	Yes	Yes	10	7	8
395	B:B:I93	B:B:Y124	4.84	Yes	Yes	10	7	6
396	B:B:I93	B:B:V133	4.61	Yes	No	0	7	4
397	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
398	B:B:C114	B:B:L95	3.17	No	Yes	10	8	8
399	B:B:L95	B:B:Y124	7.03	Yes	Yes	10	8	6
400	B:B:D118	B:B:S97	10.31	No	No	0	9	8
401	B:B:L117	B:B:W99	4.56	Yes	Yes	1	9	9
402	B:B:G116	B:B:M101	3.49	No	No	0	9	9
403	B:B:M101	B:B:Y145	7.18	No	Yes	0	9	8
404	B:B:L146	B:B:T102	2.95	Yes	No	0	7	8
405	B:B:C148	B:B:T102	3.38	No	No	0	6	8
406	B:B:C149	B:B:T102	8.45	Yes	No	0	8	8
407	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
408	B:B:V112	B:B:Y105	3.79	No	Yes	10	8	6
409	B:B:L126	B:B:Y105	3.52	Yes	Yes	10	5	6
410	B:B:A106	B:B:F151	2.77	No	Yes	0	6	9
411	B:B:N110	B:B:S108	7.45	No	No	17	4	6
412	B:B:D154	B:B:S108	8.83	No	No	17	6	6
413	B:B:K127	B:B:N110	2.8	No	No	0	4	4
414	B:B:D154	B:B:N110	6.73	No	No	17	6	4
415	B:B:I123	B:B:Y111	3.63	Yes	Yes	8	6	4
416	B:B:N125	B:B:Y111	12.79	No	Yes	0	4	4
417	B:B:S136	B:B:Y111	3.82	No	Yes	0	4	4
418	B:B:F151	B:B:Y111	3.09	Yes	Yes	8	9	4
419	B:B:L126	B:B:V112	4.47	Yes	No	10	5	8
420	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
421	B:B:C114	B:B:Y124	4.03	No	Yes	10	8	6
422	B:B:G115	B:B:L146	5.13	No	Yes	0	9	7
423	B:B:D118	B:B:I120	8.4	No	Yes	0	9	6
424	B:B:G144	B:B:N119	5.09	No	No	0	8	9
425	B:B:I120	B:B:S122	3.1	Yes	No	0	6	8
426	B:B:C121	B:B:L139	4.76	No	Yes	0	8	9
427	B:B:C121	B:B:L146	3.17	No	Yes	0	8	7
428	B:B:C121	B:B:C149	3.64	No	Yes	0	8	8
429	B:B:S122	B:B:Y124	7.63	No	Yes	0	8	6
430	B:B:I123	B:B:L139	2.85	Yes	Yes	8	6	9
431	B:B:F151	B:B:I123	6.28	Yes	Yes	8	9	6
432	B:B:I123	B:B:I157	2.94	Yes	Yes	8	6	7
433	B:B:I123	B:B:I171	5.89	Yes	No	8	6	6
434	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
435	B:B:N125	B:B:T128	4.39	No	No	0	4	3
436	B:B:K127	B:B:L126	4.23	No	Yes	0	4	5
437	B:B:E130	B:B:T128	8.47	Yes	No	0	3	3
438	B:B:E130	B:B:G131	3.27	Yes	No	0	3	4
439	B:B:E138	B:B:V135	4.28	No	No	0	6	4
440	B:B:I171	B:B:R137	2.51	No	No	0	6	5
441	B:B:I157	B:B:L139	2.85	Yes	Yes	8	7	9
442	B:B:L139	B:B:W169	9.11	Yes	Yes	8	9	8
443	B:B:H142	B:B:T159	5.48	Yes	Yes	8	9	9
444	B:B:H142	B:B:S161	13.95	Yes	No	8	9	9
445	B:B:A167	B:B:H142	2.93	No	Yes	8	4	9
446	B:B:H142	B:B:W169	9.52	Yes	Yes	8	9	8
447	B:B:H142	B:B:Q176	2.47	Yes	Yes	8	9	4
448	B:B:D163	B:B:T143	10.12	No	No	0	9	5
449	B:B:S147	B:B:Y145	2.54	No	Yes	1	9	8
450	B:B:G162	B:B:Y145	5.79	No	Yes	0	9	8
451	B:B:D186	B:B:Y145	3.45	No	Yes	1	9	8
452	B:B:M188	B:B:Y145	4.79	Yes	Yes	1	8	8
453	B:B:L146	B:B:T159	4.42	Yes	Yes	0	7	9
454	B:B:S147	B:B:S160	4.89	No	No	0	9	6
455	B:B:M188	B:B:S147	3.07	Yes	No	1	8	9
456	B:B:C148	B:B:R150	2.79	No	No	0	6	6
457	B:B:C148	B:B:L190	3.17	No	No	0	6	5
458	B:B:C149	B:B:T159	3.38	Yes	Yes	0	8	9
459	B:B:F151	B:B:I157	7.54	Yes	Yes	8	9	7
460	B:B:F151	B:B:I171	2.51	Yes	No	8	9	6
461	B:B:L152	B:B:V158	2.98	Yes	Yes	5	3	5
462	B:B:L152	B:B:L168	2.77	Yes	Yes	5	3	6
463	B:B:L152	B:B:L192	2.77	Yes	No	5	3	5
464	B:B:L152	B:B:V213	4.47	Yes	No	0	3	4
465	B:B:D153	B:B:N155	2.69	No	No	0	5	3
466	B:B:D153	B:B:Q156	3.92	No	No	0	5	5
467	B:B:D170	B:B:N155	6.73	Yes	No	5	9	3
468	B:B:E172	B:B:N155	3.94	No	No	5	6	3
469	B:B:L168	B:B:Q156	6.65	Yes	No	0	6	5
470	B:B:I157	B:B:T159	3.04	Yes	Yes	8	7	9
471	B:B:I157	B:B:W169	3.52	Yes	Yes	8	7	8
472	B:B:L190	B:B:V158	4.47	No	Yes	5	5	5
473	B:B:L192	B:B:V158	2.98	No	Yes	5	5	5
474	B:B:F199	B:B:V158	5.24	Yes	Yes	5	9	5
475	B:B:T159	B:B:W169	9.7	Yes	Yes	8	9	8
476	B:B:C166	B:B:S160	3.44	Yes	No	0	8	6
477	B:B:S160	B:B:V187	8.08	No	No	0	6	9
478	B:B:D163	B:B:S161	8.83	No	No	8	9	9
479	B:B:S161	B:B:T165	3.2	No	No	8	9	7
480	B:B:D163	B:B:T165	10.12	No	No	8	9	7
481	B:B:C166	B:B:F180	4.19	Yes	Yes	5	8	7
482	B:B:C166	B:B:F199	5.59	Yes	Yes	5	8	9
483	B:B:C166	B:B:S201	3.44	Yes	Yes	5	8	9
484	B:B:A167	B:B:W169	5.19	No	Yes	8	4	8
485	B:B:A167	B:B:Q176	6.06	No	Yes	8	4	4
486	B:B:L168	B:B:T177	2.95	Yes	No	5	6	4
487	B:B:L168	B:B:T178	8.84	Yes	No	5	6	4
488	B:B:F180	B:B:L168	2.44	Yes	Yes	5	7	6
489	B:B:Q176	B:B:W169	13.14	Yes	Yes	8	4	8
490	B:B:D170	B:B:E172	7.8	Yes	No	5	9	6
491	B:B:D170	B:B:T173	8.67	Yes	Yes	5	9	5
492	B:B:D170	B:B:T177	2.89	Yes	No	5	9	4
493	B:B:E172	B:B:T173	8.47	No	Yes	5	6	5
494	B:B:Q176	B:B:T179	8.5	Yes	No	0	4	4
495	B:B:T177	B:B:T178	3.14	No	No	5	4	4
496	B:B:F180	B:B:T178	9.08	Yes	No	5	7	4
497	B:B:F180	B:B:F199	7.5	Yes	Yes	5	7	9
498	B:B:F180	B:B:W211	13.03	Yes	Yes	5	7	8
499	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
500	B:B:G182	B:B:T181	3.64	No	No	0	6	2
501	B:B:H183	B:B:V187	8.3	Yes	No	5	9	9
502	B:B:H183	B:B:S201	5.58	Yes	Yes	5	9	9
503	B:B:A203	B:B:H183	5.85	No	Yes	0	8	9
504	B:B:H183	B:B:S207	2.79	Yes	Yes	5	9	5
505	B:B:H183	B:B:K209	15.72	Yes	Yes	5	9	6
506	B:B:H183	B:B:W211	10.58	Yes	Yes	5	9	8
507	B:B:D205	B:B:T184	10.12	Yes	No	0	9	3
508	B:B:D205	B:B:G185	3.35	Yes	No	0	9	5
509	B:B:C204	B:B:D186	3.11	Yes	No	1	7	9
510	B:B:S201	B:B:V187	3.23	Yes	No	5	9	9
511	B:B:M188	B:B:N230	2.8	Yes	No	1	8	9
512	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
513	B:B:F199	B:B:L190	9.74	Yes	No	5	9	5
514	B:B:I232	B:B:S191	6.19	Yes	No	0	8	8
515	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
516	B:B:F199	B:B:L192	2.44	Yes	No	5	9	5
517	B:B:A193	B:B:D195	3.09	No	No	0	4	5
518	B:B:A193	B:B:F234	5.55	No	Yes	0	4	5
519	B:B:G238	B:B:P194	4.06	No	No	0	7	4
520	B:B:D195	B:B:R197	13.1	No	No	0	5	5
521	B:B:D195	B:B:L198	2.71	No	No	0	5	3
522	B:B:R197	B:B:T196	3.88	No	No	0	5	1
523	B:B:R197	B:B:R214	5.33	No	No	0	5	9
524	B:B:L198	B:B:L210	6.92	No	Yes	0	3	5
525	B:B:F199	B:B:S201	3.96	Yes	Yes	5	9	9
526	B:B:F199	B:B:W211	8.02	Yes	Yes	5	9	8
527	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
528	B:B:L210	B:B:V200	4.47	Yes	No	0	5	6
529	B:B:F234	B:B:V200	6.55	Yes	No	7	5	6
530	B:B:F241	B:B:V200	14.42	Yes	No	7	6	6
531	B:B:S201	B:B:W211	4.94	Yes	Yes	5	9	8
532	B:B:G202	B:B:I229	3.53	No	No	0	6	7
533	B:B:G202	B:B:I232	3.53	No	Yes	0	6	8
534	B:B:A203	B:B:D205	3.09	No	Yes	0	8	9
535	B:B:C204	B:B:D228	9.34	Yes	Yes	1	7	9
536	B:B:D205	B:B:S207	8.83	Yes	Yes	0	9	5
537	B:B:K209	B:B:S207	3.06	Yes	Yes	5	6	5
538	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
539	B:B:K209	B:B:W211	9.28	Yes	Yes	5	6	8
540	B:B:C218	B:B:K209	8.08	Yes	Yes	5	5	6
541	B:B:K209	B:B:T221	16.52	Yes	No	5	6	7
542	B:B:L210	B:B:Q220	5.32	Yes	Yes	0	5	7
543	B:B:L210	B:B:L255	11.07	Yes	Yes	0	5	6
544	B:B:C218	B:B:W211	5.22	Yes	Yes	5	5	8
545	B:B:D212	B:B:R214	3.57	No	No	0	9	9
546	B:B:D212	B:B:E215	10.39	No	No	0	9	3
547	B:B:D212	B:B:R219	10.72	No	No	0	9	5
548	B:B:R214	B:B:V213	9.15	No	No	0	9	4
549	B:B:E215	B:B:M217	4.06	No	No	0	3	3
550	B:B:M217	B:B:R219	4.96	No	No	0	3	5
551	B:B:M217	G:G:M21	4.33	No	No	0	3	1
552	B:B:C218	B:B:T221	3.38	Yes	No	5	5	7
553	B:B:C218	G:G:Q18	7.63	Yes	No	0	5	9
554	B:B:F222	B:B:Q220	7.03	Yes	Yes	7	8	7
555	B:B:D258	B:B:Q220	9.14	Yes	Yes	7	7	7
556	B:B:Q220	G:G:E22	2.55	Yes	Yes	0	7	9
557	B:B:T221	G:G:E22	5.64	No	Yes	0	7	9
558	B:B:F222	B:B:F241	7.5	Yes	Yes	7	8	6
559	B:B:F222	B:B:F253	9.65	Yes	Yes	7	8	6
560	B:B:F222	B:B:L255	2.44	Yes	Yes	7	8	6
561	B:B:D258	B:B:F222	8.36	Yes	Yes	7	7	8
562	B:B:F253	B:B:G224	3.01	Yes	No	0	6	6
563	B:B:E226	B:B:H225	2.46	No	Yes	7	3	9
564	B:B:H225	B:B:I229	10.61	Yes	No	0	9	7
565	B:B:H225	B:B:T243	8.21	Yes	Yes	7	9	8
566	B:B:H225	B:B:S245	12.55	Yes	No	7	9	9
567	B:B:H225	B:B:T249	2.74	Yes	Yes	7	9	6
568	B:B:H225	B:B:R251	15.8	Yes	Yes	7	9	8
569	B:B:D247	B:B:E226	11.69	No	No	0	9	3
570	B:B:E226	B:B:R251	3.49	No	Yes	7	3	8
571	B:B:D247	B:B:S227	8.83	No	No	0	9	6
572	B:B:D228	B:B:D246	5.32	Yes	No	1	9	9
573	B:B:D246	B:B:N230	9.42	No	No	1	9	9
574	B:B:A231	B:B:V276	5.09	No	No	0	5	6
575	B:B:I232	B:B:T243	3.04	Yes	Yes	0	8	8
576	B:B:C233	B:B:F278	2.79	No	Yes	0	3	7
577	B:B:F234	B:B:F241	3.22	Yes	Yes	7	5	6
578	B:B:F234	B:B:L255	4.87	Yes	Yes	7	5	6
579	B:B:F235	B:B:P236	10.11	Yes	Yes	2	6	7
580	B:B:A240	B:B:F235	4.16	No	Yes	0	6	6
581	B:B:F235	B:B:F278	9.65	Yes	Yes	2	6	7
582	B:B:F235	B:B:G282	6.02	Yes	No	2	6	9
583	B:B:F235	G:G:L37	6.09	Yes	No	0	6	7
584	B:B:F235	G:G:Y40	5.16	Yes	Yes	2	6	6
585	B:B:F235	G:G:C41	2.79	Yes	No	2	6	7
586	B:B:F278	B:B:P236	4.33	Yes	Yes	2	7	7
587	B:B:G282	B:B:P236	4.06	No	Yes	2	9	7
588	B:B:P236	G:G:Y40	5.56	Yes	Yes	2	7	6
589	B:B:N237	B:B:N239	5.45	No	No	0	5	2
590	B:B:N237	G:G:Y40	19.77	No	Yes	0	5	6
591	B:B:N239	B:B:R256	12.05	No	No	0	2	9
592	B:B:F241	B:B:T243	2.59	Yes	Yes	7	6	8
593	B:B:F241	B:B:F253	8.57	Yes	Yes	7	6	6
594	B:B:F241	B:B:L255	2.44	Yes	Yes	7	6	6
595	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
596	B:B:F253	B:B:T243	9.08	Yes	Yes	7	6	8
597	B:B:G244	B:B:I273	5.29	No	No	0	5	6
598	B:B:S245	B:B:T249	4.8	No	Yes	7	9	6
599	B:B:D247	B:B:T249	2.89	No	Yes	0	9	6
600	B:B:A248	B:B:I269	4.87	No	Yes	2	5	4
601	B:B:A248	B:B:Y289	2.67	No	Yes	2	5	7
602	B:B:R251	B:B:T249	3.88	Yes	Yes	7	8	6
603	B:B:T249	B:B:T263	4.71	Yes	No	7	6	1
604	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
605	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
606	B:B:C250	B:B:I273	3.27	No	No	0	8	6
607	B:B:F253	B:B:R251	5.34	Yes	Yes	7	6	8
608	B:B:E260	B:B:R251	17.45	No	Yes	7	6	8
609	B:B:R251	B:B:T263	12.94	Yes	No	7	8	1
610	B:B:L252	B:B:L261	8.3	No	No	0	7	5
611	B:B:L252	B:B:Y264	7.03	No	Yes	0	7	5
612	B:B:F278	B:B:L252	2.44	Yes	No	0	7	7
613	B:B:E260	B:B:F253	7	No	Yes	7	6	6
614	B:B:A257	B:B:D254	4.63	No	No	0	7	9
615	B:B:D254	G:G:A33	4.63	No	No	0	9	7
616	B:B:R256	G:G:I28	8.77	No	No	0	9	4
617	B:B:R256	G:G:D36	10.72	No	No	0	9	5
618	B:B:A257	B:B:Q259	3.03	No	No	0	7	6
619	B:B:D258	G:G:R27	11.91	Yes	No	0	7	8
620	B:B:Q259	G:G:V30	4.3	No	No	0	6	8
621	B:B:E260	B:B:T263	4.23	No	No	7	6	1
622	B:B:M262	B:B:Y264	7.18	No	Yes	0	4	5
623	B:B:L285	B:B:Y264	4.69	Yes	Yes	2	6	5
624	B:B:W297	B:B:Y264	6.75	Yes	Yes	2	8	5
625	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
626	B:B:H266	B:B:I269	2.65	No	Yes	0	4	4
627	B:B:I269	B:B:Y289	9.67	Yes	Yes	2	4	7
628	B:B:D291	B:B:I269	2.8	Yes	Yes	2	8	4
629	B:B:I269	B:B:R304	2.51	Yes	Yes	2	4	5
630	B:B:C271	B:B:G272	3.92	Yes	No	2	5	4
631	B:B:C271	B:B:Y289	4.03	Yes	Yes	2	5	7
632	B:B:C271	B:B:D290	9.34	Yes	Yes	2	5	6
633	B:B:C271	B:B:D291	6.22	Yes	Yes	2	5	8
634	B:B:D290	B:B:G272	3.35	Yes	No	2	6	4
635	B:B:I273	B:B:Y289	8.46	No	Yes	0	6	7
636	B:B:S275	B:B:T274	3.2	No	No	0	8	8
637	B:B:D290	B:B:T274	2.89	Yes	No	2	6	8
638	B:B:R314	B:B:T274	2.59	Yes	No	2	8	8
639	B:B:L318	B:B:S275	6.01	Yes	No	0	6	8
640	B:B:L318	B:B:S277	3	Yes	No	0	6	5
641	B:B:G319	B:B:S277	3.71	No	No	0	5	5
642	B:B:F278	B:B:G282	4.52	Yes	No	2	7	9
643	B:B:F278	B:B:L285	8.53	Yes	Yes	2	7	6
644	B:B:L284	B:B:S279	3	Yes	No	2	5	9
645	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
646	B:B:S279	G:G:L50	4.5	No	No	2	9	9
647	B:B:K280	G:G:E47	2.7	No	No	0	1	3
648	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
649	B:B:D298	B:B:R283	15.48	No	Yes	2	9	9
650	B:B:L300	B:B:R283	7.29	No	Yes	2	6	9
651	B:B:R283	G:G:C41	2.79	Yes	No	2	9	7
652	B:B:R283	G:G:L51	3.64	Yes	Yes	2	9	6
653	B:B:L284	B:B:V296	4.47	Yes	No	0	5	5
654	B:B:L284	G:G:L50	2.77	Yes	No	2	5	9
655	B:B:L284	G:G:L51	6.92	Yes	Yes	2	5	6
656	B:B:L285	B:B:W297	3.42	Yes	Yes	2	6	8
657	B:B:L286	B:B:V296	4.47	No	No	0	7	5
658	B:B:L286	B:B:V327	4.47	No	No	0	7	6
659	B:B:A287	B:B:Y289	2.67	No	Yes	0	6	7
660	B:B:C294	B:B:G288	3.92	Yes	No	0	5	7
661	B:B:D291	B:B:Y289	6.9	Yes	Yes	2	8	7
662	B:B:N295	B:B:Y289	10.47	No	Yes	2	6	7
663	B:B:W297	B:B:Y289	6.75	Yes	Yes	2	8	7
664	B:B:D290	B:B:R314	15.48	Yes	Yes	2	6	8
665	B:B:D291	B:B:N293	6.73	Yes	No	0	8	5
666	B:B:N293	B:B:V307	2.96	No	No	0	5	3
667	B:B:A309	B:B:N293	4.69	No	No	0	3	5
668	B:B:C294	B:B:L308	3.17	Yes	No	0	5	7
669	B:B:C294	B:B:V315	5.12	Yes	No	0	5	7
670	B:B:C294	B:B:L318	3.17	Yes	Yes	2	5	6
671	B:B:C294	B:B:T329	3.38	Yes	Yes	2	5	8
672	B:B:N295	B:B:W297	4.52	No	Yes	2	6	8
673	B:B:N295	B:B:R304	13.26	No	Yes	2	6	5
674	B:B:R304	B:B:W297	3	Yes	Yes	2	5	8
675	B:B:D298	B:B:K301	9.68	No	Yes	0	9	5
676	B:B:L300	G:G:M38	2.83	No	No	2	6	4
677	B:B:L300	G:G:C41	6.35	No	No	2	6	7
678	B:B:D303	B:B:K301	6.91	No	Yes	0	2	5
679	B:B:R304	B:B:V307	2.62	Yes	No	0	5	3
680	B:B:L308	B:B:W339	21.64	No	Yes	0	7	9
681	B:B:H311	B:B:T329	5.48	Yes	Yes	2	9	8
682	B:B:H311	B:B:S331	16.74	Yes	No	2	9	9
683	B:B:D333	B:B:H311	5.04	Yes	Yes	2	9	9
684	B:B:H311	B:B:K337	13.1	Yes	Yes	2	9	6
685	B:B:D312	B:B:N313	4.04	No	Yes	2	5	7
686	B:B:D312	B:B:D333	11.98	No	Yes	2	5	9
687	B:B:N313	B:B:W332	5.65	Yes	Yes	2	7	9
688	B:B:D333	B:B:N313	2.69	Yes	Yes	2	9	7
689	B:B:R314	B:B:W332	20.99	Yes	Yes	2	8	9
690	B:B:S316	B:B:W332	4.94	No	Yes	2	9	9
691	B:B:L318	B:B:T329	4.42	Yes	Yes	2	6	8
692	B:B:V320	B:B:V327	3.21	No	No	0	7	6
693	B:B:D323	B:B:T321	5.78	No	No	4	7	7
694	B:B:D323	B:B:M325	4.16	No	Yes	4	7	5
695	B:B:M325	G:G:P49	6.71	Yes	No	0	5	7
696	B:B:M325	G:G:N59	2.8	Yes	Yes	4	5	9
697	B:B:M325	G:G:P60	5.03	Yes	Yes	4	5	9
698	B:B:M325	G:G:F61	3.73	Yes	Yes	4	5	8
699	B:B:A326	B:B:N340	6.25	No	Yes	4	7	9
700	B:B:A326	G:G:F61	5.55	No	Yes	4	7	8
701	B:B:T329	B:B:W339	6.06	Yes	Yes	2	8	9
702	B:B:D333	B:B:S331	8.83	Yes	No	2	9	9
703	B:B:D333	B:B:F335	14.33	Yes	No	2	9	4
704	B:B:K337	B:B:W339	9.28	Yes	Yes	2	6	9
705	B:B:I338	G:G:F61	3.77	No	Yes	4	5	8
706	B:B:N340	G:G:N59	6.81	Yes	Yes	4	9	9
707	B:B:N340	G:G:F61	3.62	Yes	Yes	4	9	8
708	G:G:I9	G:G:R13	3.76	No	No	0	2	6
709	G:G:M21	G:G:Q18	4.08	No	No	0	1	9
710	G:G:E22	G:G:Q18	3.82	Yes	No	0	9	9
711	G:G:E22	G:G:I25	2.73	Yes	No	0	9	2
712	G:G:I28	G:G:K32	2.91	No	No	0	4	5
713	G:G:E42	G:G:M38	5.41	No	No	2	1	4
714	G:G:H44	G:G:Y40	6.53	No	Yes	0	6	6
715	G:G:A43	G:G:H44	2.93	No	No	0	4	6
716	G:G:E47	G:G:H44	4.92	No	No	0	3	6
717	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
718	G:G:D48	G:G:L51	14.93	Yes	Yes	0	9	6
719	G:G:P55	G:G:V54	5.3	No	No	4	5	6
720	G:G:E58	G:G:V54	4.28	No	No	4	5	6
721	G:G:N59	G:G:V54	5.91	Yes	No	4	9	6
722	G:G:P55	G:G:S57	3.56	No	No	4	5	6
723	G:G:E58	G:G:P55	12.58	No	No	4	5	5
724	G:G:A56	G:G:R62	8.3	No	No	0	4	7
725	G:G:E58	G:G:S57	7.19	No	No	4	5	6
726	G:G:N59	G:G:P60	6.52	Yes	Yes	4	9	9
727	G:G:N59	G:G:R62	12.05	Yes	No	0	9	7
728	G:G:F61	G:G:P60	2.89	Yes	Yes	4	8	9
729	R:R:F582	R:R:T567	3.89	Yes	No	0	1	9
730	R:R:S568	R:R:S570	3.26	Yes	No	0	9	9
731	R:R:I571	R:R:S568	4.64	No	Yes	0	7	9
732	R:R:S568	R:R:V577	9.7	Yes	No	0	9	3
733	R:R:F569	R:R:L572	7.31	Yes	Yes	3	9	9
734	R:R:F569	R:R:T589	5.19	Yes	No	0	9	9
735	R:R:F569	R:R:F641	3.22	Yes	Yes	3	9	9
736	R:R:F569	R:R:F823	5.36	Yes	Yes	3	9	9
737	R:R:F569	R:R:N827	3.62	Yes	Yes	3	9	9
738	R:R:H820	R:R:S570	8.37	No	No	0	8	9
739	R:R:F641	R:R:L572	2.44	Yes	Yes	3	9	9
740	R:R:L572	R:R:Y668	7.03	Yes	Yes	3	9	8
741	R:R:F747	R:R:L572	4.87	Yes	Yes	3	8	9
742	R:R:F747	R:R:M573	2.49	Yes	No	3	8	9
743	R:R:G807	R:R:M573	5.24	No	No	3	9	9
744	R:R:F823	R:R:M573	2.49	Yes	No	3	9	9
745	R:R:P575	R:R:S574	3.56	Yes	No	0	6	9
746	R:R:S574	R:R:T810	4.8	No	Yes	0	9	7
747	R:R:P575	R:R:W737	8.11	Yes	No	0	6	6
748	R:R:F576	R:R:S814	2.64	No	No	0	3	5
749	R:R:P578	R:R:V577	3.53	Yes	No	0	4	3
750	R:R:I581	R:R:P578	5.08	Yes	Yes	0	4	4
751	R:R:H820	R:R:P578	4.58	No	Yes	0	8	4
752	R:R:I581	R:R:V585	3.07	Yes	No	0	4	8
753	R:R:I581	R:R:L817	9.99	Yes	No	0	4	2
754	R:R:I581	R:R:V821	3.07	Yes	No	0	4	7
755	R:R:F582	R:R:P583	4.33	Yes	No	0	1	1
756	R:R:F582	R:R:K586	6.2	Yes	No	0	1	3
757	R:R:K586	R:R:Y590	11.94	No	No	0	3	5
758	R:R:I595	R:R:V591	3.07	No	No	0	7	7
759	R:R:F829	R:R:G592	4.52	Yes	No	0	7	9
760	R:R:F641	R:R:L593	2.44	Yes	No	0	9	8
761	R:R:I642	R:R:L593	4.28	No	No	0	8	8
762	R:R:F829	R:R:I595	10.05	Yes	No	0	7	7
763	R:R:F832	R:R:I595	3.77	Yes	No	0	5	7
764	R:R:I597	R:R:S596	3.1	Yes	No	18	7	9
765	R:R:D638	R:R:S596	4.42	No	No	18	7	9
766	R:R:I597	R:R:L635	2.85	Yes	No	0	7	8
767	R:R:D638	R:R:I597	2.8	No	Yes	18	7	7
768	R:R:G831	R:R:S599	3.71	No	No	0	9	8
769	R:R:F832	R:R:S599	2.64	Yes	No	0	5	8
770	R:R:L835	R:R:S599	7.51	No	No	0	8	8
771	R:R:L600	R:R:L634	9.69	No	No	0	9	9
772	R:R:L600	R:R:L635	5.54	No	No	0	9	8
773	R:R:L602	R:R:L835	2.77	No	No	0	6	8
774	R:R:C603	R:R:I839	3.27	No	No	0	7	7
775	R:R:F610	R:R:I606	3.77	Yes	No	0	8	8
776	R:R:I606	R:R:L849	4.28	No	No	0	8	7
777	R:R:E607	R:R:W611	4.36	No	No	0	9	9
778	R:R:E607	R:R:R624	10.47	No	Yes	0	9	9
779	R:R:E607	R:R:V628	2.85	No	No	0	9	7
780	R:R:F610	R:R:L609	7.31	Yes	No	0	8	4
781	R:R:F610	R:R:I614	3.77	Yes	No	19	8	7
782	R:R:F610	R:R:L845	2.44	Yes	Yes	19	8	8
783	R:R:F610	R:R:L848	12.18	Yes	No	0	8	7
784	R:R:K612	R:R:W611	10.44	No	No	0	7	9
785	R:R:K615	R:R:W611	11.6	Yes	No	0	8	9
786	R:R:I614	R:R:Q613	5.49	No	No	0	7	5
787	R:R:I614	R:R:L845	2.85	No	Yes	19	7	8
788	R:R:K615	R:R:S620	3.06	Yes	No	0	8	8
789	R:R:H621	R:R:K615	28.82	No	Yes	0	6	8
790	R:R:K615	R:R:R624	2.48	Yes	Yes	0	8	9
791	R:R:Q618	R:R:S617	2.89	No	No	0	7	8
792	R:R:S617	R:R:T619	3.2	No	No	0	8	8
793	R:R:H692	R:R:Q618	7.42	No	No	0	6	7
794	R:R:Q618	R:R:Q695	3.84	No	No	0	7	6
795	R:R:R685	R:R:T619	14.23	Yes	No	0	8	8
796	R:R:R623	R:R:S620	3.95	No	No	0	9	8
797	R:R:L681	R:R:T622	5.9	No	Yes	3	7	7
798	R:R:R685	R:R:T622	3.88	Yes	Yes	3	8	7
799	R:R:M698	R:R:T622	4.52	No	Yes	3	8	7
800	R:R:M699	R:R:T622	4.52	Yes	Yes	3	7	7
801	R:R:T622	W:W:?1	2.69	Yes	Yes	3	7	0
802	R:R:R623	R:R:R624	8.53	No	Yes	20	9	9
803	R:R:M627	R:R:R623	7.44	No	No	20	7	9
804	R:R:M627	R:R:R624	2.48	No	Yes	20	7	9
805	R:R:I625	R:R:M699	4.37	No	Yes	3	7	7
806	R:R:F703	R:R:I625	2.51	Yes	No	3	8	7
807	R:R:I625	W:W:?1	2.61	No	Yes	3	7	0
808	R:R:C626	R:R:W674	2.61	No	Yes	3	7	9
809	R:R:C626	W:W:?1	4.35	No	Yes	3	7	0
810	R:R:L799	R:R:M627	2.83	No	No	0	6	7
811	R:R:N629	R:R:W674	22.6	No	Yes	3	9	9
812	R:R:F703	R:R:N629	8.46	Yes	No	3	8	9
813	R:R:N629	R:R:Y707	5.81	No	Yes	3	9	9
814	R:R:I630	R:R:L671	2.85	No	Yes	0	8	7
815	R:R:I630	R:R:W674	3.52	No	Yes	0	8	9
816	R:R:I636	R:R:L632	5.71	No	No	0	7	5
817	R:R:F667	R:R:S633	2.64	Yes	Yes	3	8	8
818	R:R:S633	R:R:S670	3.26	Yes	Yes	3	8	8
819	R:R:L671	R:R:S633	3	Yes	Yes	0	7	8
820	R:R:S633	R:R:Y707	3.82	Yes	Yes	3	8	9
821	R:R:D638	R:R:L634	5.43	No	No	0	7	9
822	R:R:L634	R:R:L671	4.15	No	Yes	0	9	7
823	R:R:F667	R:R:I636	15.07	Yes	No	0	8	7
824	R:R:A637	R:R:F667	2.77	No	Yes	0	9	8
825	R:R:A637	R:R:Y668	4	No	Yes	0	9	8
826	R:R:V643	R:R:W640	3.68	No	Yes	0	8	6
827	R:R:A660	R:R:W640	2.59	No	Yes	0	7	6
828	R:R:F663	R:R:W640	15.03	No	Yes	3	8	6
829	R:R:T664	R:R:W640	3.64	Yes	Yes	3	7	6
830	R:R:F667	R:R:W640	3.01	Yes	Yes	3	8	6
831	R:R:F641	R:R:T664	3.89	Yes	Yes	3	9	7
832	R:R:F641	R:R:Y668	5.16	Yes	Yes	3	9	8
833	R:R:V647	R:R:V656	4.81	Yes	No	0	5	5
834	R:R:D648	R:R:V651	5.84	No	No	0	5	1
835	R:R:N652	R:R:V651	4.43	Yes	No	0	4	1
836	R:R:G655	R:R:N652	5.09	No	Yes	0	3	4
837	R:R:N652	R:R:V656	7.39	Yes	No	0	4	5
838	R:R:S654	R:R:T658	3.2	No	No	0	4	6
839	R:R:C657	R:R:C733	7.28	No	No	0	9	9
840	R:R:V661	R:R:Y727	3.79	No	Yes	0	8	9
841	R:R:V661	R:R:W734	4.9	No	Yes	0	8	8
842	R:R:F662	R:R:S714	3.96	No	No	0	8	9
843	R:R:F662	R:R:I718	8.79	No	No	0	8	7
844	R:R:F663	R:R:F667	4.29	No	Yes	3	8	8
845	R:R:T664	R:R:Y668	8.74	Yes	Yes	3	7	8
846	R:R:T664	R:R:W734	4.85	Yes	Yes	3	7	8
847	R:R:H665	R:R:S714	4.18	No	No	0	9	9
848	R:R:A746	R:R:H665	2.93	No	No	0	9	9
849	R:R:F747	R:R:H665	9.05	Yes	No	0	8	9
850	R:R:F666	R:R:F667	9.65	No	Yes	0	7	8
851	R:R:F666	R:R:P710	2.89	No	Yes	0	7	9
852	R:R:F666	R:R:S714	5.28	No	No	0	7	9
853	R:R:F667	R:R:S670	2.64	Yes	Yes	3	8	8
854	R:R:W734	R:R:Y668	4.82	Yes	Yes	3	8	8
855	R:R:F747	R:R:Y668	7.22	Yes	Yes	3	8	8
856	R:R:F673	R:R:L669	9.74	Yes	No	0	8	9
857	R:R:I713	R:R:L669	2.85	Yes	No	0	9	9
858	R:R:S670	R:R:Y707	3.82	Yes	Yes	3	8	9
859	R:R:P710	R:R:S670	3.56	Yes	Yes	0	9	8
860	R:R:L671	R:R:M675	5.65	Yes	No	0	7	9
861	R:R:A751	R:R:F672	8.32	No	No	0	9	9
862	R:R:F672	R:R:V755	2.62	No	No	0	9	8
863	R:R:F672	R:R:W804	17.04	No	Yes	0	9	9
864	R:R:C709	R:R:F673	5.59	No	Yes	0	8	8
865	R:R:F673	R:R:P710	7.22	Yes	Yes	0	8	9
866	R:R:F673	R:R:I754	5.02	Yes	No	0	8	9
867	R:R:M677	R:R:W674	4.65	No	Yes	3	6	9
868	R:R:F703	R:R:W674	8.02	Yes	Yes	3	8	9
869	R:R:W674	R:R:Y707	10.61	Yes	Yes	3	9	9
870	R:R:W674	W:W:?1	7.29	Yes	Yes	3	9	0
871	R:R:G801	R:R:M675	3.49	No	No	0	9	9
872	R:R:M675	R:R:Q830	2.72	No	Yes	0	9	9
873	R:R:I680	R:R:L676	2.85	No	No	0	8	7
874	R:R:I754	R:R:L676	11.42	No	No	0	9	7
875	R:R:L676	R:R:V757	2.98	No	No	0	7	7
876	R:R:L705	R:R:M677	4.24	No	No	0	6	6
877	R:R:M677	W:W:?1	5.17	No	Yes	3	6	0
878	R:R:L678	R:R:L682	2.77	No	No	0	8	9
879	R:R:L678	R:R:L800	5.54	No	Yes	21	8	9
880	R:R:I680	W:W:?1	6.52	No	Yes	0	8	0
881	R:R:L681	R:R:R685	12.15	No	Yes	3	7	8
882	R:R:L681	W:W:?1	11.38	No	Yes	3	7	0
883	R:R:A683	R:R:V761	3.39	No	No	0	6	8
884	R:R:L688	R:R:Y684	7.03	Yes	No	3	6	8
885	R:R:H691	R:R:Y684	8.71	No	No	3	7	8
886	R:R:Y684	W:W:?1	31.07	No	Yes	3	8	0
887	R:R:I686	R:R:L764	2.85	No	No	0	7	7
888	R:R:I686	R:R:K768	5.82	No	No	0	7	8
889	R:R:I687	R:R:L688	7.14	No	Yes	3	6	6
890	R:R:I687	W:W:?1	2.61	No	Yes	3	6	0
891	R:R:H691	R:R:L688	2.57	No	Yes	3	7	6
892	R:R:L688	W:W:?1	5.06	Yes	Yes	3	6	0
893	R:R:F690	R:R:V689	11.8	Yes	Yes	9	8	9
894	R:R:H696	R:R:Q695	7.42	No	No	0	5	6
895	R:R:M699	R:R:Q695	6.8	Yes	No	0	7	6
896	R:R:L697	R:R:V701	2.98	No	No	0	3	6
897	R:R:M698	W:W:?1	5.17	No	Yes	3	8	0
898	R:R:M699	W:W:?1	6.46	Yes	Yes	3	7	0
899	R:R:G702	W:W:?1	4.69	No	Yes	0	7	0
900	R:R:F703	R:R:Y707	3.09	Yes	Yes	3	8	9
901	R:R:L711	R:R:V715	2.98	No	No	0	7	6
902	R:R:I713	R:R:I716	2.94	Yes	No	0	9	7
903	R:R:A746	R:R:I713	3.25	No	Yes	0	9	9
904	R:R:T717	R:R:Y727	2.5	No	Yes	0	9	9
905	R:R:I718	R:R:Y727	8.46	No	Yes	0	7	9
906	R:R:T721	R:R:T726	3.14	Yes	Yes	12	9	4
907	R:R:T721	R:R:Y727	6.24	Yes	Yes	0	9	9
908	R:R:S741	R:R:T721	4.8	Yes	Yes	12	8	9
909	R:R:P743	R:R:T721	8.74	Yes	Yes	12	8	9
910	R:R:S724	R:R:T726	9.59	No	Yes	0	3	4
911	R:R:K728	R:R:N725	5.6	No	No	0	5	4
912	R:R:N736	R:R:T726	2.92	Yes	Yes	12	8	4
913	R:R:S741	R:R:T726	7.99	Yes	Yes	12	8	4
914	R:R:L735	R:R:Y727	9.38	Yes	Yes	0	9	9
915	R:R:N736	R:R:R729	10.85	Yes	No	0	8	5
916	R:R:G740	R:R:R729	4.5	No	No	0	4	5
917	R:R:D731	R:R:V732	5.84	No	No	0	3	4
918	R:R:L735	R:R:W734	4.56	Yes	Yes	0	9	8
919	R:R:F747	R:R:W734	5.01	Yes	Yes	3	8	8
920	R:R:L735	R:R:P743	3.28	Yes	Yes	0	9	8
921	R:R:L735	R:R:L744	5.54	Yes	No	0	9	8
922	R:R:N736	R:R:S741	4.47	Yes	Yes	12	8	8
923	R:R:N736	R:R:P743	4.89	Yes	Yes	12	8	8
924	R:R:L744	R:R:W737	4.56	No	No	0	8	6
925	R:R:P743	R:R:S741	7.13	Yes	Yes	12	8	8
926	R:R:K742	R:R:L745	5.64	No	No	0	7	8
927	R:R:L744	R:R:V748	2.98	No	No	0	8	7
928	R:R:L745	R:R:V749	2.98	No	No	0	8	7
929	R:R:I811	R:R:V748	4.61	No	No	0	5	7
930	R:R:P750	R:R:V749	7.07	No	No	0	9	7
931	R:R:I808	R:R:L752	7.14	No	No	0	7	8
932	R:R:I754	R:R:N758	4.25	No	No	0	9	9
933	R:R:L800	R:R:N758	15.1	Yes	No	0	9	9
934	R:R:F759	R:R:L763	4.87	No	No	0	4	4
935	R:R:L796	R:R:V762	4.47	No	No	0	9	8
936	R:R:L802	R:R:V762	2.98	No	No	0	7	8
937	R:R:L764	R:R:T767	2.95	No	No	0	7	4
938	R:R:K768	R:R:T767	3	No	No	0	8	4
939	R:R:K768	R:R:R771	2.48	No	No	0	8	8
940	R:R:L769	R:R:V789	5.96	No	No	0	7	8
941	R:R:L769	R:R:S792	3	No	No	0	7	8
942	R:R:T785	R:R:W770	3.64	No	Yes	0	7	6
943	R:R:I786	R:R:W770	3.52	No	Yes	0	6	6
944	R:R:V789	R:R:W770	7.36	No	Yes	0	8	6
945	R:R:P772	R:R:R771	7.21	No	No	0	7	8
946	R:R:R777	R:R:T773	6.47	Yes	No	0	5	6
947	R:R:R777	R:R:R780	5.33	Yes	Yes	0	5	3
948	R:R:L778	R:R:S779	3	Yes	No	0	5	4
949	R:R:A784	R:R:D781	4.63	No	No	0	6	6
950	R:R:D781	R:R:T785	7.23	No	No	0	6	7
951	R:R:D782	R:R:K783	2.77	No	No	0	7	6
952	R:R:R788	R:R:T785	6.47	No	No	0	7	7
953	R:R:L793	R:R:T797	2.95	No	No	0	7	9
954	R:R:I795	R:R:L841	7.14	No	No	0	7	5
955	R:R:L796	R:R:L800	6.92	No	Yes	0	9	9
956	R:R:P798	R:R:T797	3.5	No	No	0	9	9
957	R:R:L802	R:R:T797	7.37	No	No	0	7	9
958	R:R:F833	R:R:P798	2.89	Yes	No	22	7	9
959	R:R:F837	R:R:P798	5.78	Yes	No	22	8	9
960	R:R:I834	R:R:L799	4.28	No	No	0	9	6
961	R:R:G801	R:R:W804	2.81	No	Yes	0	9	9
962	R:R:L826	R:R:T803	4.42	No	No	0	6	9
963	R:R:N827	R:R:T803	8.77	Yes	No	3	9	9
964	R:R:Q830	R:R:T803	2.83	Yes	No	3	9	9
965	R:R:F823	R:R:W804	3.01	Yes	Yes	3	9	9
966	R:R:N827	R:R:W804	11.3	Yes	Yes	3	9	9
967	R:R:Q830	R:R:W804	14.24	Yes	Yes	3	9	9
968	R:R:F806	R:R:W819	3.01	No	No	23	8	6
969	R:R:F806	R:R:I822	3.77	No	No	23	8	5
970	R:R:F806	R:R:L826	3.65	No	No	0	8	6
971	R:R:G807	R:R:T810	3.64	No	Yes	0	9	7
972	R:R:F823	R:R:G807	3.01	Yes	No	3	9	9
973	R:R:I808	R:R:I811	5.89	No	No	0	7	5
974	R:R:G809	R:R:V812	3.68	No	No	0	7	6
975	R:R:I811	R:R:T810	3.04	No	Yes	0	5	7
976	R:R:H820	R:R:T810	5.48	No	Yes	0	8	7
977	R:R:D813	R:R:V812	4.38	No	No	0	4	6
978	R:R:D813	R:R:Q815	7.83	No	No	0	4	3
979	R:R:D813	R:R:N816	12.12	No	No	0	4	5
980	R:R:N816	R:R:W819	11.3	No	No	0	5	6
981	R:R:I822	R:R:W819	3.52	No	No	23	5	6
982	R:R:F823	R:R:N827	12.08	Yes	Yes	3	9	9
983	R:R:F829	R:R:L825	2.44	Yes	No	0	7	5
984	R:R:F833	R:R:L826	2.44	Yes	No	0	7	6
985	R:R:N827	R:R:Q830	3.96	Yes	Yes	3	9	9
986	R:R:F829	R:R:F833	4.29	Yes	Yes	0	7	7
987	R:R:G831	R:R:I834	3.53	No	No	0	9	9
988	R:R:F832	R:R:F833	4.29	Yes	Yes	0	5	7
989	R:R:C836	R:R:F832	8.38	No	Yes	0	7	5
990	R:R:F833	R:R:F837	4.29	Yes	Yes	22	7	8
991	R:R:I839	R:R:L835	4.28	No	No	0	7	8
992	R:R:C836	R:R:F837	2.79	No	Yes	0	7	8
993	R:R:F837	R:R:L841	6.09	Yes	No	0	8	5
994	R:R:I839	R:R:L845	2.85	No	Yes	0	7	8
995	R:R:D842	R:R:L845	4.07	No	Yes	0	9	8
996	R:R:R846	R:R:S843	2.64	No	No	0	7	5
997	R:R:F850	R:R:R846	4.28	No	No	0	3	7
998	R:R:K852	R:R:N851	2.8	No	No	0	4	4
999	B:B:L7	G:G:R13	2.43	Yes	No	0	8	6
1000	B:B:F292	B:B:N313	2.42	No	Yes	0	4	7
1001	B:B:N268	B:B:R304	2.41	No	Yes	0	4	5
1002	B:B:E130	B:B:R134	2.33	Yes	No	0	3	3
1003	R:R:L766	R:R:W770	2.28	No	Yes	0	7	6
1004	A:A:E289	A:A:Y302	2.24	No	No	0	6	6
1005	A:A:G202	A:A:G203	2.11	No	No	0	9	9
1006	R:R:G706	R:R:P710	2.03	No	Yes	0	9	9
1007	R:R:G708	R:R:P710	2.03	No	Yes	0	6	9
1008	A:A:R208	A:A:W211	2	No	Yes	0	9	9
1009	B:B:A140	B:B:G141	1.95	No	No	0	5	5
1010	B:B:A231	B:B:G244	1.95	No	No	0	5	5
1011	B:B:A309	B:B:G310	1.95	No	No	0	3	5
1012	R:R:A828	R:R:G592	1.95	No	No	0	8	9
1013	R:R:A660	R:R:G644	1.95	No	No	0	7	6
1014	B:B:A106	B:B:P107	1.87	No	No	0	6	6
1015	B:B:A193	B:B:P194	1.87	No	No	0	4	4
1016	A:A:G202	A:A:V201	1.84	No	Yes	0	9	9
1017	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
1018	B:B:G324	B:B:V320	1.84	No	No	0	9	7
1019	R:R:G644	R:R:V647	1.84	No	Yes	0	6	5
1020	R:R:G679	R:R:V761	1.84	No	No	0	9	8
1021	R:R:G702	R:R:V701	1.84	No	No	0	7	6
1022	R:R:G805	R:R:V755	1.84	No	No	0	6	8
1023	B:B:G185	B:B:T164	1.82	No	No	0	5	6
1024	B:B:G174	B:B:T173	1.82	No	Yes	0	4	5
1025	B:B:A60	B:B:C103	1.81	No	No	0	7	8
1026	B:B:A104	B:B:C149	1.81	No	Yes	0	7	8
1027	R:R:P575	R:R:S738	1.78	Yes	No	0	6	2
1028	R:R:P575	R:R:S814	1.78	Yes	No	0	6	5
1029	B:B:G306	B:B:I43	1.76	No	No	0	4	3
1030	R:R:G594	R:R:I597	1.76	No	Yes	0	5	7
1031	R:R:G598	R:R:I601	1.76	No	No	0	3	5
1032	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1033	R:R:P578	R:R:T580	1.75	Yes	No	0	4	3
1034	A:A:G27	B:B:L55	1.71	No	No	0	5	6
1035	A:A:A41	A:A:S246	1.71	No	No	0	7	9
1036	B:B:A56	B:B:S74	1.71	No	No	0	7	9
1037	B:B:G330	B:B:L336	1.71	No	Yes	0	5	7
1038	R:R:C657	R:R:V647	1.71	No	Yes	0	9	5
1039	R:R:G679	R:R:L678	1.71	No	No	21	9	8
1040	R:R:G679	R:R:L800	1.71	No	Yes	21	9	9
1041	R:R:G708	R:R:L711	1.71	No	No	0	6	7
1042	R:R:G790	R:R:L793	1.71	No	No	0	5	7
1043	R:R:G838	R:R:L799	1.71	No	No	0	8	6
1044	A:A:A219	A:A:V34	1.7	No	Yes	0	7	5
1045	B:B:A11	G:G:V16	1.7	No	No	0	5	7
1046	B:B:A26	G:G:V30	1.7	No	No	0	3	8
1047	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
1048	B:B:A305	B:B:V296	1.7	No	No	0	4	5
1049	R:R:A824	R:R:V585	1.7	No	No	0	8	8
1050	R:R:C733	R:R:T649	1.69	No	No	0	9	3
1051	R:R:I713	R:R:P750	1.69	Yes	No	0	9	9
1052	A:A:G352	R:R:D842	1.68	No	No	0	8	9
1053	B:B:D76	B:B:G77	1.68	No	No	0	9	8
1054	R:R:A645	R:R:T567	1.68	No	No	0	7	9
1055	R:R:K728	R:R:P653	1.67	No	No	0	5	4
1056	R:R:N652	R:R:P653	1.63	Yes	No	0	4	4
1057	A:A:A299	A:A:I278	1.62	No	No	0	7	6
1058	B:B:I18	G:G:A23	1.62	No	No	0	7	8
1059	B:B:I33	G:G:A34	1.62	No	No	0	3	6
1060	B:B:A140	B:B:I120	1.62	No	Yes	0	5	6
1061	A:A:A12	A:A:K10	1.61	No	No	0	4	3
1062	B:B:D38	B:B:P39	1.61	No	No	0	1	1
1063	B:B:S207	B:B:T223	1.6	Yes	No	0	5	2
1064	A:A:C305	R:R:L778	1.59	No	Yes	0	3	5
1065	R:R:T646	R:R:V647	1.59	No	Yes	0	5	5
1066	R:R:T721	R:R:V720	1.59	Yes	No	0	9	5
1067	A:A:A301	R:R:L778	1.58	No	Yes	0	3	5
1068	B:B:L14	G:G:A23	1.58	Yes	No	0	8	8
1069	B:B:L30	G:G:A34	1.58	Yes	No	0	5	6
1070	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
1071	R:R:A631	R:R:L600	1.58	No	No	0	8	9
1072	R:R:A631	R:R:L604	1.58	No	No	0	8	8
1073	R:R:A694	R:R:L697	1.58	No	No	0	8	3
1074	R:R:P723	R:R:Q722	1.58	No	No	0	8	7
1075	R:R:A818	R:R:L817	1.58	No	No	0	6	2
1076	B:B:A28	B:B:D27	1.54	No	Yes	0	4	8
1077	R:R:I571	R:R:V732	1.54	No	No	0	7	4
1078	R:R:I581	R:R:V584	1.54	Yes	No	0	4	3
1079	R:R:I597	R:R:V639	1.54	Yes	No	0	7	6
1080	A:A:K51	A:A:S47	1.53	No	No	0	9	9
1081	R:R:K791	R:R:S843	1.53	No	No	0	8	5
1082	A:A:K10	A:A:V13	1.52	No	No	0	3	3
1083	A:A:K51	A:A:V50	1.52	No	No	0	9	6
1084	B:B:Q17	G:G:A23	1.52	No	No	0	4	8
1085	A:A:K330	A:A:T327	1.5	No	No	0	4	8
1086	B:B:L4	G:G:S8	1.5	No	No	0	4	4
1087	B:B:N132	B:B:V133	1.48	No	No	0	3	4
1088	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
1089	R:R:I597	R:R:I601	1.47	Yes	No	0	7	5
1090	R:R:I712	R:R:I716	1.47	No	No	0	5	7
1091	A:A:D200	A:A:V185	1.46	No	No	0	9	5
1092	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1093	R:R:I786	R:R:K783	1.45	No	No	0	6	6
1094	G:G:Q11	G:G:S8	1.44	No	No	0	3	4
1095	R:R:Q847	R:R:S843	1.44	No	No	0	6	5
1096	B:B:L4	G:G:I9	1.43	No	No	0	4	2
1097	R:R:I588	R:R:L825	1.43	No	No	0	9	5
1098	B:B:Q175	B:B:T173	1.42	No	Yes	0	4	5
1099	B:B:L14	G:G:K20	1.41	Yes	No	0	8	6
1100	B:B:G182	B:B:W211	1.41	No	Yes	0	6	8
1101	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
1102	A:A:D20	A:A:K17	1.38	No	No	0	6	4
1103	A:A:A31	A:A:R32	1.38	No	No	0	4	4
1104	A:A:D309	A:A:K314	1.38	No	No	0	4	3
1105	A:A:D350	R:R:K616	1.38	No	No	0	4	7
1106	G:G:A10	G:G:R13	1.38	No	No	0	2	6
1107	R:R:D731	R:R:K730	1.38	No	No	0	3	2
1108	R:R:I718	R:R:Q722	1.37	No	No	0	7	7
1109	A:A:E14	A:A:K17	1.35	No	No	0	3	4
1110	G:G:E17	G:G:K14	1.35	No	No	0	6	4
1111	G:G:E17	G:G:M21	1.35	No	No	0	6	1
1112	A:A:Q304	R:R:L778	1.33	No	Yes	0	5	5
1113	R:R:F582	R:R:S568	1.32	Yes	Yes	0	1	9
1114	A:A:E25	A:A:N22	1.31	No	No	0	4	4
1115	R:R:H691	R:R:M693	1.31	No	No	0	7	5
1116	A:A:D26	A:A:E25	1.3	No	No	0	5	4
1117	B:B:I120	B:B:R96	1.25	Yes	No	0	6	6
1118	A:A:K17	A:A:R21	1.24	No	No	0	4	4
1119	A:A:F189	A:A:M53	1.24	No	No	0	9	8
1120	A:A:E245	A:A:H244	1.23	No	No	0	9	4
1121	R:R:F759	R:R:L802	1.22	No	No	0	4	7
1122	R:R:F837	R:R:L794	1.22	Yes	No	0	8	6
1123	B:B:E130	B:B:R129	1.16	Yes	No	0	3	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:V34	5.472	5	9	5
2	A:A:L36	4.2575	4	9	7
3	A:A:L37	2.972	5	1	9
4	A:A:L38	5.275	4	6	8
5	A:A:L39	3.7675	4	1	9
6	A:A:K46	5.068	5	6	9
7	A:A:I49	5.63	4	6	7
8	A:A:I184	3.4925	4	1	9
9	A:A:F191	8.82	4	9	5
10	A:A:L194	7.5125	4	9	4
11	A:A:F196	8.818	5	9	7
12	A:A:K197	10.005	4	1	6
13	A:A:M198	3.465	4	6	7
14	A:A:F199	7.915	4	1	5
15	A:A:V201	3.435	4	1	9
16	A:A:Q204	5.51143	7	1	9
17	A:A:E207	5.388	5	1	9
18	A:A:K210	5.60375	8	1	9
19	A:A:W211	5.00286	7	1	9
20	A:A:F215	3.84889	9	1	9
21	A:A:F223	3.215	4	1	9
22	A:A:Y230	9.606	5	1	8
23	A:A:R242	7.674	5	11	9
24	A:A:F250	5.04	4	1	9
25	A:A:I253	3.83	4	1	8
26	A:A:W258	5.758	5	2	5
27	A:A:F259	5.308	5	1	9
28	A:A:I264	5.5675	4	1	6
29	A:A:I265	4.524	5	6	8
30	A:A:L266	3.6975	4	1	9
31	A:A:F267	5.406	5	6	9
32	A:A:N269	6.04	4	6	9
33	A:A:F274	9.268	5	1	9
34	A:A:F307	4.31	5	1	8
35	A:A:R313	5.09	4	0	4
36	A:A:K317	7.7375	4	1	7
37	A:A:Y320	4.82286	7	6	7
38	A:A:H322	8.4475	4	6	9
39	A:A:F323	5.566	5	0	4
40	A:A:F334	7.252	5	6	3
41	A:A:F336	6.1125	4	9	8
42	A:A:V339	4.685	4	9	8
43	A:A:F354	5.82667	6	0	5
44	B:B:L7	3.3875	4	14	8
45	B:B:L14	3.554	5	15	8
46	B:B:D27	4.3375	4	0	8
47	B:B:L30	3.23	4	0	5
48	B:B:I37	5.765	4	2	2
49	B:B:V40	4.364	5	2	3
50	B:B:M45	5.3375	4	0	4
51	B:B:T50	4.2275	4	2	3
52	B:B:L51	8.666	5	4	9
53	B:B:H54	8.902	5	4	9
54	B:B:Y59	6.808	5	2	8
55	B:B:W63	6.594	5	0	7
56	B:B:L70	4.736	5	4	5
57	B:B:S72	4.568	5	4	9
58	B:B:Q75	5.9075	4	0	9
59	B:B:K78	4.91	4	0	8
60	B:B:L79	3.995	6	10	7
61	B:B:I80	8.73	4	4	8
62	B:B:W82	10.0317	6	4	9
63	B:B:Y85	9.08	4	4	4
64	B:B:K89	7	6	4	9
65	B:B:H91	4.462	5	10	5
66	B:B:I93	3.708	5	10	7
67	B:B:L95	4.334	5	10	8
68	B:B:W99	6.23	6	1	9
69	B:B:Y105	5.03429	7	10	6
70	B:B:Y111	5.8325	4	8	4
71	B:B:L117	4.706	5	1	9
72	B:B:I120	3.5925	4	0	6
73	B:B:I123	4.318	5	8	6
74	B:B:Y124	5.716	5	10	6
75	B:B:L126	4.072	5	10	5
76	B:B:E130	3.8075	4	0	3
77	B:B:L139	4.8925	4	8	9
78	B:B:H142	6.87	5	8	9
79	B:B:Y145	4.74667	9	1	8
80	B:B:L146	3.9175	4	0	7
81	B:B:C149	4.32	4	0	8
82	B:B:F151	4.39167	6	8	9
83	B:B:L152	3.2475	4	5	3
84	B:B:I157	3.978	5	8	7
85	B:B:V158	3.9175	4	5	5
86	B:B:T159	5.204	5	8	9
87	B:B:C166	4.165	4	5	8
88	B:B:L168	4.73	5	5	6
89	B:B:W169	8.36333	6	8	8
90	B:B:D170	6.5225	4	5	9
91	B:B:T173	5.095	4	5	5
92	B:B:Q176	7.5425	4	8	4
93	B:B:F180	6.54167	6	5	7
94	B:B:H183	8.13667	6	5	9
95	B:B:M188	5.185	4	1	8
96	B:B:F199	5.63875	8	5	9
97	B:B:S201	4.23	5	5	9
98	B:B:C204	5.085	4	1	7
99	B:B:D205	6.3475	4	0	9
100	B:B:S207	4.07	4	5	5
101	B:B:K209	10.532	5	5	6
102	B:B:L210	6.945	4	0	5
103	B:B:W211	7.49714	7	5	8
104	B:B:C218	6.0775	4	5	5
105	B:B:Q220	6.01	4	7	7
106	B:B:F222	6.996	5	7	8
107	B:B:H225	7.69	7	7	9
108	B:B:D228	6.218	5	1	9
109	B:B:I232	4.35	4	0	8
110	B:B:F234	5.36	5	7	5
111	B:B:F235	6.28286	7	2	6
112	B:B:P236	6.015	4	2	7
113	B:B:F241	5.93	7	7	6
114	B:B:T243	5.73	4	7	8
115	B:B:T249	3.97	6	7	6
116	B:B:R251	9.81667	6	7	8
117	B:B:F253	7.10833	6	7	6
118	B:B:L255	5.205	4	7	6
119	B:B:D258	10.6275	4	7	7
120	B:B:Y264	5.39167	6	2	5
121	B:B:I269	4.5	5	2	4
122	B:B:C271	5.8775	4	2	5
123	B:B:F278	5.00429	7	2	7
124	B:B:R283	7.41833	6	2	9
125	B:B:L284	4.29	4	2	5
126	B:B:L285	4.555	4	2	6
127	B:B:Y289	6.4525	8	2	7
128	B:B:D290	7.765	4	2	6
129	B:B:D291	5.6625	4	2	8
130	B:B:C294	3.752	5	2	5
131	B:B:W297	4.888	5	2	8
132	B:B:K301	7.275	4	0	5
133	B:B:R304	4.76	5	2	5
134	B:B:H311	10.09	4	2	9
135	B:B:N313	3.7	4	2	7
136	B:B:R314	11.015	4	2	8
137	B:B:L318	4.15	4	2	6
138	B:B:M325	4.486	5	4	5
139	B:B:T329	4.835	4	2	8
140	B:B:W332	8.81286	7	2	9
141	B:B:D333	8.574	5	2	9
142	B:B:L336	6.566	5	4	7
143	B:B:K337	8.975	4	2	6
144	B:B:W339	11.67	4	2	9
145	B:B:N340	5.866	5	4	9
146	G:G:E22	3.685	4	0	9
147	G:G:Y40	9.255	4	2	6
148	G:G:D48	9.3225	4	0	9
149	G:G:L51	5.988	5	2	6
150	G:G:N59	6.818	5	4	9
151	G:G:P60	6.3925	4	4	9
152	G:G:F61	5.07125	8	4	8
153	R:R:S568	4.73	4	0	9
154	R:R:F569	4.94	5	3	9
155	R:R:L572	5.4125	4	3	9
156	R:R:P575	3.8075	4	0	6
157	R:R:P578	3.735	4	0	4
158	R:R:I581	4.55	5	0	4
159	R:R:F582	3.935	4	0	1
160	R:R:I597	2.25333	6	18	7
161	R:R:F610	5.894	5	19	8
162	R:R:K615	11.49	4	0	8
163	R:R:T622	4.302	5	3	7
164	R:R:R624	5.99	4	20	9
165	R:R:S633	3.18	4	3	8
166	R:R:W640	5.59	5	3	6
167	R:R:F641	3.43	5	3	9
168	R:R:V647	2.4875	4	0	5
169	R:R:N652	4.635	4	0	4
170	R:R:T664	5.28	4	3	7
171	R:R:F667	5.72429	7	3	8
172	R:R:Y668	6.16167	6	3	8
173	R:R:S670	3.32	4	3	8
174	R:R:L671	3.9125	4	0	7
175	R:R:F673	6.8925	4	0	8
176	R:R:W674	8.47143	7	3	9
177	R:R:R685	8.298	5	3	8
178	R:R:L688	5.45	4	3	6
179	R:R:V689	6.4575	4	9	9
180	R:R:F690	7.09833	6	9	8
181	R:R:M699	5.5375	4	3	7
182	R:R:F703	5.52	4	3	8
183	R:R:Y707	5.43	5	3	9
184	R:R:P710	3.546	5	0	9
185	R:R:I713	2.6825	4	0	9
186	R:R:T721	4.902	5	12	9
187	R:R:T726	5.91	4	12	4
188	R:R:Y727	6.074	5	0	9
189	R:R:W734	4.828	5	3	8
190	R:R:L735	5.69	4	0	9
191	R:R:N736	5.7825	4	12	8
192	R:R:S741	6.0975	4	12	8
193	R:R:P743	6.01	4	12	8
194	R:R:F747	5.728	5	3	8
195	R:R:W770	4.2	4	0	6
196	R:R:R777	5.6325	4	0	5
197	R:R:L778	1.875	4	0	5
198	R:R:R780	5.8975	4	1	3
199	R:R:L800	7.3175	4	21	9
200	R:R:W804	9.68	5	3	9
201	R:R:T810	4.24	4	0	7
202	R:R:F823	5.19	5	3	9
203	R:R:N827	7.946	5	3	9
204	R:R:F829	5.325	4	0	7
205	R:R:Q830	5.9375	4	3	9
206	R:R:F832	4.77	4	0	5
207	R:R:F833	3.64	5	22	7
208	R:R:F837	4.034	5	22	8
209	R:R:L845	3.0525	4	19	8
210	W:W:?1	7.31308	13	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:G319	B:B:W63	11.6464	2.81	No	Yes	0	5	7
2	B:B:G319	B:B:S277	11.8021	3.71	No	No	0	5	5
3	B:B:L318	B:B:S277	11.9727	3	Yes	No	0	6	5
4	B:B:L318	B:B:S275	20.4106	6.01	Yes	No	0	6	8
5	B:B:S275	B:B:T274	20.5837	3.2	No	No	0	8	8
6	B:B:R314	B:B:T274	20.6117	2.59	Yes	No	2	8	8
7	B:B:R314	B:B:W332	36.8094	20.99	Yes	Yes	2	8	9
8	B:B:K57	B:B:W332	31.3461	13.92	No	Yes	0	9	9
9	B:B:K57	B:B:Q75	31.6712	6.78	No	Yes	0	9	9
10	A:A:C214	B:B:Q75	31.6234	4.58	No	Yes	0	7	9
11	A:A:C214	A:A:F215	31.6569	2.79	No	Yes	0	7	9
12	A:A:F215	A:A:L37	82.1115	2.44	Yes	Yes	1	9	9
13	A:A:L37	A:A:L39	99.9276	4.15	Yes	Yes	1	9	9
14	A:A:F223	A:A:L39	100	2.44	Yes	Yes	1	9	9
15	A:A:F223	A:A:L266	75.0095	2.44	Yes	Yes	1	9	9
16	A:A:L266	A:A:T321	55.2423	4.42	Yes	No	0	9	5
17	A:A:T321	R:R:R777	54.1318	2.59	No	Yes	0	5	5
18	A:A:E318	R:R:R777	53.9693	8.14	No	Yes	0	4	5
19	A:A:E318	A:A:Y320	53.9247	7.86	No	Yes	0	4	7
20	A:A:I265	A:A:Y320	43.4362	4.84	Yes	Yes	6	8	7
21	A:A:I222	A:A:I265	42.9196	5.89	No	Yes	0	7	8
22	A:A:I222	A:A:L36	43.179	7.14	No	Yes	0	7	7
23	A:A:L36	A:A:V339	41.5618	4.47	Yes	Yes	9	7	8
24	A:A:V339	R:R:F690	41.7958	2.62	Yes	Yes	9	8	8
25	A:A:I343	R:R:F690	41.5488	6.28	No	Yes	9	7	8
26	A:A:I343	A:A:N347	41.5929	2.83	No	No	0	7	8
27	A:A:N347	R:R:R685	41.5531	8.44	No	Yes	0	8	8
28	B:B:W332	B:B:Y59	32.4172	3.86	Yes	Yes	2	9	8
29	B:B:Q75	B:B:Y59	31.7655	7.89	Yes	Yes	0	9	8
30	B:B:Q75	B:B:W99	31.8261	4.38	Yes	Yes	0	9	9
31	A:A:F215	B:B:W99	31.8674	5.01	Yes	Yes	1	9	9
32	A:A:W211	B:B:Y145	35.6765	5.79	Yes	Yes	1	9	8
33	A:A:V201	A:A:W211	18.0031	3.68	Yes	Yes	1	9	9
34	B:B:H62	B:B:Y105	11.5931	4.36	No	Yes	0	6	6
35	B:B:H62	B:B:R150	11.6805	14.67	No	No	0	6	6
36	B:B:C148	B:B:R150	11.7702	2.79	No	No	0	6	6
37	B:B:C148	B:B:L190	21.4174	3.17	No	No	0	6	5
38	B:B:F199	B:B:L190	21.3692	9.74	Yes	No	5	9	5
39	B:B:C166	B:B:F199	21.358	5.59	Yes	Yes	5	8	9
40	B:B:C166	B:B:S160	25.0469	3.44	Yes	No	0	8	6
41	B:B:S147	B:B:S160	35.554	4.89	No	No	0	9	6
42	B:B:S147	B:B:Y145	35.5377	2.54	No	Yes	1	9	8
43	A:A:F223	A:A:F250	20.6011	5.36	Yes	Yes	1	9	9
44	A:A:F250	A:A:I264	20.3258	6.28	Yes	Yes	1	9	6
45	A:A:I264	A:A:L266	19.9264	4.28	Yes	Yes	1	6	9
46	A:A:I264	A:A:K317	39.5396	5.82	Yes	Yes	1	6	7
47	A:A:K317	A:A:R313	39.2767	3.71	Yes	Yes	0	7	4
48	A:A:R313	A:A:T260	19.7983	10.35	Yes	No	0	4	3
49	A:A:D261	A:A:T260	19.6931	8.67	No	No	0	4	3
50	A:A:R313	A:A:T316	19.7983	2.59	Yes	No	0	4	3
51	A:A:D261	A:A:T316	19.6931	4.34	No	No	0	4	3
52	A:A:D261	A:A:K349	39.1484	2.77	No	No	0	4	5
53	A:A:F354	A:A:K349	38.675	2.48	Yes	No	0	5	5
54	A:A:F354	R:R:L769	41.2023	2.44	Yes	No	0	5	7
55	R:R:L769	R:R:S792	39.1418	3	No	No	0	7	8
56	A:A:L353	R:R:S792	38.8369	6.01	No	No	0	7	8
57	A:A:L353	R:R:L682	38.228	2.77	No	No	0	7	9
58	B:B:C271	B:B:D290	15.8404	9.34	Yes	Yes	2	5	6
59	B:B:C271	B:B:Y289	14.0356	4.03	Yes	Yes	2	5	7
60	B:B:W297	B:B:Y289	11.3514	6.75	Yes	Yes	2	8	7
61	B:B:M45	B:B:N340	16.5139	4.21	Yes	Yes	0	4	9
62	B:B:L308	B:B:M45	30.5088	8.48	No	Yes	0	7	4
63	B:B:M45	G:G:L50	11.6811	2.83	Yes	No	0	4	9
64	B:B:L308	B:B:W339	15.6081	21.64	No	Yes	0	7	9
65	B:B:H311	B:B:T329	16.4394	5.48	Yes	Yes	2	9	8
66	B:B:D333	B:B:H311	24.8823	5.04	Yes	Yes	2	9	9
67	B:B:C148	B:B:T102	11.311	3.38	No	No	0	6	8
68	B:B:C294	B:B:L308	15.5868	3.17	Yes	No	0	5	7
69	B:B:D333	B:B:N313	25.9226	2.69	Yes	Yes	2	9	7
70	R:R:R685	R:R:T622	21.3305	3.88	Yes	Yes	3	8	7
71	R:R:T622	W:W:?1	20.846	2.69	Yes	Yes	3	7	0
72	R:R:W674	W:W:?1	39.0685	7.29	Yes	Yes	3	9	0
73	R:R:I630	R:R:W674	19.6119	3.52	No	Yes	0	8	9
74	R:R:I630	R:R:L671	19.4772	2.85	No	Yes	0	8	7
75	R:R:L671	R:R:M675	17.7423	5.65	Yes	No	0	7	9
76	R:R:F823	R:R:W804	10.0216	3.01	Yes	Yes	3	9	9
77	R:R:F823	R:R:G807	14.2474	3.01	Yes	No	3	9	9
78	R:R:G807	R:R:T810	14.0352	3.64	No	Yes	0	9	7
79	R:R:H820	R:R:T810	10.1149	5.48	No	Yes	0	8	7
80	R:R:L681	R:R:R685	20.9045	12.15	No	Yes	3	7	8
81	R:R:L681	W:W:?1	20.8462	11.38	No	Yes	3	7	0
82	R:R:M675	R:R:Q830	11.7461	2.72	No	Yes	0	9	9
83	R:R:W674	R:R:Y707	19.0928	10.61	Yes	Yes	3	9	9
84	R:R:F667	R:R:W640	10.7632	3.01	Yes	Yes	3	8	6
85	R:R:L678	R:R:L682	36.4339	2.77	No	No	0	8	9
86	R:R:L678	R:R:L800	35.1146	5.54	No	Yes	21	8	9
87	R:R:L800	R:R:N758	13.3844	15.1	Yes	No	0	9	9
88	R:R:I754	R:R:N758	13.0613	4.25	No	No	0	9	9
89	R:R:F673	R:R:I754	12.1562	5.02	Yes	No	0	8	9
90	R:R:L796	R:R:L800	21.5114	6.92	No	Yes	0	9	9
91	R:R:L796	R:R:V762	21.1775	4.47	No	No	0	9	8
92	R:R:L802	R:R:V762	20.846	2.98	No	No	0	7	8
93	R:R:L802	R:R:T797	19.8682	7.37	No	No	0	7	9
94	R:R:P798	R:R:T797	18.8993	3.5	No	No	0	9	9
95	R:R:F833	R:R:P798	16.9216	2.89	Yes	No	22	7	9
96	R:R:F832	R:R:F833	11.7316	4.29	Yes	Yes	0	5	7
97	R:R:F832	R:R:S599	10.6986	2.64	Yes	No	0	5	8
98	A:A:L37	A:A:V201	18.0629	2.98	Yes	Yes	1	9	9
99	A:A:F215	A:A:W211	18.232	4.01	Yes	Yes	1	9	9
100	B:B:S160	B:B:V187	10.4295	8.08	No	No	0	6	9
101	B:B:D290	B:B:R314	16.0549	15.48	Yes	Yes	2	6	8
102	B:B:N313	B:B:W332	26.4381	5.65	Yes	Yes	2	7	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L681	R:R:T622	5.9	3	No	Yes	7	7	1	1
R:R:R685	R:R:T622	3.88	3	Yes	Yes	8	7	2	1
R:R:M698	R:R:T622	4.52	3	No	Yes	8	7	1	1
R:R:M699	R:R:T622	4.52	3	Yes	Yes	7	7	1	1
R:R:T622	W:W:?1	2.69	3	Yes	Yes	7	0	1	0
R:R:I625	R:R:M699	4.37	3	No	Yes	7	7	1	1
R:R:F703	R:R:I625	2.51	3	Yes	No	8	7	2	1
R:R:I625	W:W:?1	2.61	3	No	Yes	7	0	1	0
R:R:C626	R:R:W674	2.61	3	No	Yes	7	9	1	1
R:R:C626	W:W:?1	4.35	3	No	Yes	7	0	1	0
R:R:N629	R:R:W674	22.6	3	No	Yes	9	9	2	1
R:R:F703	R:R:N629	8.46	3	Yes	No	8	9	2	2
R:R:N629	R:R:Y707	5.81	3	No	Yes	9	9	2	2
R:R:I630	R:R:W674	3.52	0	No	Yes	8	9	2	1
R:R:M677	R:R:W674	4.65	3	No	Yes	6	9	1	1
R:R:F703	R:R:W674	8.02	3	Yes	Yes	8	9	2	1
R:R:W674	R:R:Y707	10.61	3	Yes	Yes	9	9	1	2
R:R:W674	W:W:?1	7.29	3	Yes	Yes	9	0	1	0
R:R:I680	R:R:L676	2.85	0	No	No	8	7	1	2
R:R:L705	R:R:M677	4.24	0	No	No	6	6	2	1
R:R:M677	W:W:?1	5.17	3	No	Yes	6	0	1	0
R:R:I680	W:W:?1	6.52	0	No	Yes	8	0	1	0
R:R:L681	R:R:R685	12.15	3	No	Yes	7	8	1	2
R:R:L681	W:W:?1	11.38	3	No	Yes	7	0	1	0
R:R:L688	R:R:Y684	7.03	3	Yes	No	6	8	1	1
R:R:H691	R:R:Y684	8.71	3	No	No	7	8	2	1
R:R:Y684	W:W:?1	31.07	3	No	Yes	8	0	1	0
R:R:I687	R:R:L688	7.14	3	No	Yes	6	6	1	1
R:R:I687	W:W:?1	2.61	3	No	Yes	6	0	1	0
R:R:H691	R:R:L688	2.57	3	No	Yes	7	6	2	1
R:R:L688	W:W:?1	5.06	3	Yes	Yes	6	0	1	0
R:R:M699	R:R:Q695	6.8	3	Yes	No	7	6	1	2
R:R:M698	W:W:?1	5.17	3	No	Yes	8	0	1	0
R:R:M699	W:W:?1	6.46	3	Yes	Yes	7	0	1	0
R:R:G702	W:W:?1	4.69	0	No	Yes	7	0	1	0
R:R:F703	R:R:Y707	3.09	3	Yes	Yes	8	9	2	2
R:R:G702	R:R:V701	1.84	0	No	No	7	6	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
69.23	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/β1/γ2
56.25	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/β1/γ2
53.33	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/β1/γ2
31.25	Single	9K1C	DHA	9K1C-FFA1-DHA-Gi1/β1/γ2
29.17	Single	5KW2	PubChem 133053953	5KW2-FFA1-PubChem 133053953
28.57	Single	5XSZ	Glyceryl-mono-oleate	5XSZ-LPA₆-Glyceryl-mono-oleate
23.53	Single	9CM3	Compound 187	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
22.22	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
19.05	Single	9IYB	A1D5Q	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
17.65	Single	8XXU	A1D5Q	8XXU-DP₂-A1D5Q-Gi1/β1/γ2
16.00	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
15.79	Single	8Y72	BMS-986122	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
15.79	Single	9JCQ	LPC	9JCQ-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
15.00	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
13.64	Single	9CM7	AZ-1729	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
13.04	Single	8XXV	A1D5Q	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
11.76	Single	9NS9	Compound 187	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
10.53	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
10.53	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
10.53	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
10.53	Single	8K9L	BMS-986122	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
10.53	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	7LJC	Mevidalen	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
10.00	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/β1/γ2
9.09	Single	6C1R	Avacopan; Na	6C1R-C5a₁-PMX53-Avacopan; Na
8.70	Single	8YYX	Leukotriene e4	8YYX-Oxoglutarate-Leukotriene e4-chim(Gi1-CtGq)/β1/γ2
6.25	Single	4PXF	Octyl-Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl-β-D-Glucopyranoside-Arrestin1 Finger Loop
5.56	Single	6KQI	Org27569	6KQI-CB₁-CP55940-Org27569
5.26	Single	6OBA	GTPL11074	6OBA-β₂-S-Alprenolol-GTPL11074
5.00	Single	9JCO	LPC	9JCO-GPR4-LPC-chim(NtGi1-Gs)/β1/γ2
4.76	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
4.55	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
4.55	Single	8IYX	YL-365	8IYX-GPR34-YL-365

PDB Summary
PDB	7WU4
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRF1
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	K6G
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3.4
Date	2022-04-27
D.O.I.	doi.org/10.1038/s41586-022-04580-w

Net Summary
I_min	2.44
Number of Linked Nodes	842
Number of Links	1123
Number of Hubs	210
Number of Links mediated by Hubs	754
Number of Communities	23
Number of Nodes involved in Communities	307
Number of Links involved in Communities	488

Path Summary
Number Of Nodes in MetaPath	103
Number Of Links MetaPath	102
Number of Shortest Paths	4456634
Length Of Smallest Path	3
Average Path Length	33.6667
Length of Longest Path	54
Minimum Path Strength	1.295
Average Path Strength	5.43287
Maximum Path Strength	21.225
Minimum Path Correlation	0.71
Average Path Correlation	0.993743
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.0303
Average % Of Corr. Nodes	38.853
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	59.5118
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cell surface receptor signaling pathway • regulation of lipid metabolic process • primary metabolic process • metabolic process • regulation of metabolic process • lipid metabolic process • regulation of primary metabolic process • fat cell differentiation • cellular developmental process • cell differentiation • behavior • learning or memory • cognition • memory • nervous system development • cellular component organization • cellular component biogenesis • cell junction organization • cellular component assembly • cell junction assembly • synapse organization • cellular component organization or biogenesis • synapse assembly • energy derivation by oxidation of organic compounds • energy reserve metabolic process • generation of precursor metabolites and energy • plasma membrane bounded cell projection organization • cell projection organization • cell development • neuron projection development • generation of neurons • neurogenesis • neuron differentiation • neuron development • cytoplasmic vesicle • intracellular vesicle
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	K6G
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	K6G
Name	[(2~{R})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] hexadecanoate
Synonyms
Identifier
Formula	C24 H51 N O7 P
Molecular Weight	496.638
SMILES
PubChem
Formal Charge	0
Total Atoms	84
Total Chiral Atoms	1
Total Bonds	83
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>7WU4_Chain_A K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A D N S G K S T I V K Q M T G I V E T H F T F K D L H F K M F D V G G Q R S E R K K W I H C F E D V A A I I F C V D L S D Y N R M H E S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y Q E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C A T D T K N A Q F I F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>7WU4_Chain_B S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>7WU4_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q5T601
Sequence	>7WU4_Chain_R T S F S I L M S P F V P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W K Q I K K S Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V D T T V N P S G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L V F H H M A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q P S N T Y K R K D V C W L N W S N G S K P L L A F V V P A L A I V A V N F V V V L L V L T K L W R P T V G E R L S R D D K A T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S Q N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L R Q L L F N K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8G2Y	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC	chim(Gs-CtGq)/β1/γ2	3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	8G2Y (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC		3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	7WU3	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gs/β1/γ2	3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU3 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WXU	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXU (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1L-G13)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-G12)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	Gi1/β1/γ2	3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4

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