psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:T567	R:R:Y590	9.99	No	No	0	9	5
2	R:R:A645	R:R:T567	5.03	No	No	0	7	9
3	R:R:T567	R:R:V732	4.76	No	No	0	9	4
4	R:R:S568	R:R:S570	4.89	No	No	0	9	9
5	R:R:S568	R:R:V577	9.7	No	No	0	9	3
6	R:R:S568	R:R:V585	6.46	No	No	0	9	8
7	R:R:F569	R:R:L572	6.09	Yes	Yes	0	9	9
8	R:R:F569	R:R:T589	7.78	Yes	No	0	9	9
9	R:R:F569	R:R:L593	6.09	Yes	No	0	9	8
10	R:R:F569	R:R:W804	5.01	Yes	Yes	1	9	9
11	R:R:F569	R:R:F823	5.36	Yes	Yes	1	9	9
12	R:R:A828	R:R:F569	4.16	No	Yes	0	8	9
13	R:R:S570	R:R:S574	6.52	No	No	1	9	9
14	R:R:H820	R:R:S570	11.16	Yes	No	1	8	9
15	R:R:I571	R:R:R729	11.27	No	No	0	7	5
16	R:R:I571	R:R:V732	4.61	No	No	0	7	4
17	R:R:I571	R:R:W734	4.7	No	Yes	0	7	8
18	R:R:F641	R:R:L572	3.65	No	Yes	0	9	9
19	R:R:L572	R:R:Y668	7.03	Yes	Yes	0	9	8
20	R:R:L572	R:R:W734	4.56	Yes	Yes	0	9	8
21	R:R:F747	R:R:M573	6.22	Yes	Yes	1	8	9
22	R:R:M573	R:R:V748	4.56	Yes	No	1	9	7
23	R:R:L752	R:R:M573	4.24	No	Yes	0	8	9
24	R:R:G807	R:R:M573	3.49	No	Yes	0	9	9
25	R:R:I811	R:R:M573	4.37	No	Yes	1	5	9
26	R:R:F823	R:R:M573	6.22	Yes	Yes	1	9	9
27	R:R:S574	R:R:T810	3.2	No	Yes	1	9	7
28	R:R:H820	R:R:S574	6.97	Yes	No	1	8	9
29	R:R:P575	R:R:W737	8.11	No	No	0	6	6
30	R:R:F576	R:R:P578	5.78	No	Yes	0	3	4
31	R:R:P578	R:R:V577	3.53	Yes	No	0	4	3
32	R:R:F582	R:R:V577	3.93	No	No	0	1	3
33	R:R:I581	R:R:P578	5.08	Yes	Yes	0	4	4
34	R:R:H820	R:R:P578	7.63	Yes	Yes	0	8	4
35	R:R:I581	R:R:V585	4.61	Yes	No	0	4	8
36	R:R:I581	R:R:Q815	4.12	Yes	No	0	4	3
37	R:R:F582	R:R:P583	4.33	No	No	0	1	1
38	R:R:F582	R:R:K586	9.93	No	No	0	1	3
39	R:R:K586	R:R:W587	10.44	No	No	0	3	4
40	R:R:W587	R:R:Y590	9.65	No	No	0	4	5
41	R:R:A824	R:R:I588	3.25	No	No	0	8	9
42	R:R:F829	R:R:G592	7.53	No	No	0	7	9
43	R:R:D638	R:R:L593	5.43	Yes	No	0	7	8
44	R:R:I642	R:R:L593	7.14	No	No	0	8	8
45	R:R:F832	R:R:I595	3.77	No	No	0	5	7
46	R:R:D638	R:R:S596	4.42	Yes	No	0	7	9
47	R:R:G831	R:R:S596	3.71	No	No	0	9	9
48	R:R:D638	R:R:I597	4.2	Yes	No	0	7	7
49	R:R:I597	R:R:V639	4.61	No	No	0	7	6
50	R:R:F832	R:R:S599	5.28	No	No	0	5	8
51	R:R:L835	R:R:S599	7.51	No	No	0	8	8
52	R:R:L600	R:R:L634	9.69	No	No	0	9	9
53	R:R:L600	R:R:L635	4.15	No	No	0	9	8
54	R:R:G831	R:R:L600	3.42	No	No	0	9	9
55	R:R:I601	R:R:L635	4.28	No	No	0	5	8
56	R:R:L602	R:R:L835	4.15	No	No	0	6	8
57	R:R:C603	R:R:I839	4.91	No	No	0	7	7
58	R:R:A631	R:R:L604	4.73	No	No	0	8	8
59	R:R:I606	R:R:L845	4.28	No	No	0	8	8
60	R:R:E607	R:R:W611	3.27	No	No	3	9	9
61	R:R:E607	R:R:R624	9.3	No	Yes	0	9	9
62	R:R:E607	R:R:V628	7.13	No	No	3	9	7
63	R:R:F610	R:R:Q613	5.86	Yes	No	4	8	5
64	R:R:F610	R:R:L848	4.87	Yes	No	4	8	7
65	R:R:F610	R:R:L849	4.87	Yes	No	0	8	7
66	R:R:F610	R:R:K852	4.96	Yes	No	0	8	4
67	R:R:V628	R:R:W611	3.68	No	No	3	7	9
68	R:R:L848	R:R:Q613	9.32	No	No	4	7	5
69	R:R:I614	R:R:R624	5.01	No	Yes	0	7	9
70	R:R:H621	R:R:K615	3.93	No	No	0	6	8
71	R:R:S617	R:R:S620	6.52	No	No	0	8	8
72	R:R:R685	R:R:T619	16.82	Yes	No	0	8	8
73	R:R:H621	R:R:I625	9.28	No	No	0	6	7
74	R:R:H621	R:R:Q695	7.42	No	No	0	6	6
75	R:R:L681	R:R:T622	5.9	No	No	0	7	7
76	R:R:Q695	R:R:T622	4.25	No	No	0	6	7
77	R:R:M698	R:R:T622	6.02	No	No	0	8	7
78	R:R:R623	R:R:R624	5.33	No	Yes	0	9	9
79	R:R:M627	R:R:R623	8.69	No	No	0	7	9
80	R:R:D842	R:R:R624	4.76	No	Yes	0	9	9
81	R:R:L845	R:R:R624	3.64	No	Yes	0	8	9
82	R:R:I625	R:R:M699	5.83	No	No	0	7	7
83	R:R:C626	R:R:W674	3.92	No	Yes	0	7	9
84	R:R:C626	R:R:L678	3.17	No	No	0	7	8
85	R:R:L799	R:R:M627	8.48	No	No	0	6	7
86	R:R:N629	R:R:W674	23.73	No	Yes	2	9	9
87	R:R:F703	R:R:N629	8.46	Yes	No	2	8	9
88	R:R:N629	R:R:Y707	8.14	No	Yes	2	9	9
89	R:R:I630	R:R:W674	3.52	No	Yes	0	8	9
90	R:R:I630	R:R:M675	4.37	No	Yes	0	8	9
91	R:R:I636	R:R:L632	7.14	No	No	0	7	5
92	R:R:L632	R:R:Y707	3.52	No	Yes	0	5	9
93	R:R:S633	R:R:S670	6.52	No	No	2	8	8
94	R:R:S633	R:R:Y707	3.82	No	Yes	2	8	9
95	R:R:D638	R:R:L634	10.86	Yes	No	0	7	9
96	R:R:L634	R:R:L671	5.54	No	No	0	9	7
97	R:R:F667	R:R:I636	21.35	No	No	0	8	7
98	R:R:A637	R:R:Y668	9.34	No	Yes	0	9	8
99	R:R:D638	R:R:Y668	4.6	Yes	Yes	0	7	8
100	R:R:V643	R:R:W640	6.13	No	No	0	8	6
101	R:R:F663	R:R:W640	19.04	No	No	0	8	6
102	R:R:G644	R:R:V643	3.68	No	No	0	6	8
103	R:R:V647	R:R:V656	3.21	No	No	0	5	5
104	R:R:C657	R:R:V647	3.42	No	No	0	9	5
105	R:R:D648	R:R:T650	7.23	No	No	0	5	3
106	R:R:T650	R:R:V651	3.17	No	No	0	3	1
107	R:R:N652	R:R:V651	4.43	No	No	0	4	1
108	R:R:N652	R:R:V656	5.91	No	No	0	4	5
109	R:R:G655	R:R:S654	3.71	No	No	0	3	4
110	R:R:C657	R:R:C733	7.28	No	No	0	9	9
111	R:R:K728	R:R:T658	7.51	No	No	0	5	6
112	R:R:V661	R:R:Y727	7.57	No	Yes	0	8	9
113	R:R:F662	R:R:S714	7.93	Yes	No	0	8	9
114	R:R:F662	R:R:V715	3.93	Yes	No	0	8	6
115	R:R:F662	R:R:I718	6.28	Yes	No	1	8	7
116	R:R:F662	R:R:Y727	7.22	Yes	Yes	1	8	9
117	R:R:F663	R:R:F667	7.5	No	No	0	8	8
118	R:R:T664	R:R:Y668	3.75	No	Yes	0	7	8
119	R:R:T664	R:R:W734	7.28	No	Yes	0	7	8
120	R:R:H665	R:R:L669	5.14	Yes	Yes	1	9	9
121	R:R:H665	R:R:S714	4.18	Yes	No	0	9	9
122	R:R:H665	R:R:Y727	5.44	Yes	Yes	1	9	9
123	R:R:H665	R:R:W734	3.17	Yes	Yes	1	9	8
124	R:R:F747	R:R:H665	3.39	Yes	Yes	1	8	9
125	R:R:F666	R:R:F667	15	No	No	0	7	8
126	R:R:F666	R:R:L711	6.09	No	No	0	7	7
127	R:R:F666	R:R:S714	5.28	No	No	0	7	9
128	R:R:F747	R:R:Y668	7.22	Yes	Yes	0	8	8
129	R:R:L669	R:R:P710	3.28	Yes	No	0	9	9
130	R:R:F747	R:R:L669	4.87	Yes	Yes	1	8	9
131	R:R:L669	R:R:P750	6.57	Yes	No	0	9	9
132	R:R:S670	R:R:Y707	7.63	No	Yes	2	8	9
133	R:R:P710	R:R:S670	3.56	No	No	0	9	8
134	R:R:L671	R:R:M675	7.07	No	Yes	0	7	9
135	R:R:F672	R:R:M675	7.46	Yes	Yes	0	9	9
136	R:R:F672	R:R:F747	5.36	Yes	Yes	0	9	8
137	R:R:A751	R:R:F672	9.71	No	Yes	0	9	9
138	R:R:F672	R:R:W804	23.05	Yes	Yes	0	9	9
139	R:R:C709	R:R:F673	9.78	No	Yes	0	8	8
140	R:R:F673	R:R:I754	5.02	Yes	No	0	8	9
141	R:R:M677	R:R:W674	4.65	No	Yes	0	6	9
142	R:R:F703	R:R:W674	8.02	Yes	Yes	2	8	9
143	R:R:G706	R:R:W674	8.44	No	Yes	0	9	9
144	R:R:W674	R:R:Y707	12.54	Yes	Yes	2	9	9
145	R:R:G801	R:R:M675	3.49	No	Yes	0	9	9
146	R:R:I680	R:R:L676	7.14	No	No	0	8	7
147	R:R:I754	R:R:L676	12.85	No	No	0	9	7
148	R:R:G702	R:R:M677	5.24	No	No	0	7	6
149	R:R:L678	R:R:L800	4.15	No	No	0	8	9
150	R:R:G679	R:R:V761	3.68	No	No	0	9	8
151	R:R:L681	R:R:R685	3.64	No	Yes	0	7	8
152	R:R:R685	R:R:Y684	14.4	Yes	Yes	0	8	8
153	R:R:L688	R:R:Y684	4.69	No	Yes	0	6	8
154	R:R:H691	R:R:Y684	13.07	No	Yes	0	7	8
155	R:R:M693	R:R:Y684	8.38	No	Yes	0	5	8
156	R:R:H692	R:R:R685	4.51	No	Yes	0	6	8
157	R:R:I686	R:R:K768	4.36	No	No	0	7	8
158	R:R:M693	R:R:M698	7.22	No	No	0	5	8
159	R:R:A694	R:R:H696	4.39	No	No	0	8	5
160	R:R:F703	R:R:M699	3.73	Yes	No	0	8	7
161	R:R:F703	R:R:Y707	4.13	Yes	Yes	2	8	9
162	R:R:T717	R:R:Y727	3.75	No	Yes	0	9	9
163	R:R:A746	R:R:T717	5.03	No	No	0	9	9
164	R:R:I718	R:R:Y727	16.92	No	Yes	1	7	9
165	R:R:T721	R:R:T726	6.28	No	No	0	9	4
166	R:R:T721	R:R:Y727	8.74	No	Yes	0	9	9
167	R:R:P743	R:R:T721	5.25	No	No	0	8	9
168	R:R:S741	R:R:T726	9.59	No	No	0	8	4
169	R:R:L735	R:R:Y727	7.03	No	Yes	0	9	9
170	R:R:D731	R:R:R729	5.96	No	No	0	3	5
171	R:R:N736	R:R:R729	10.85	No	No	0	8	5
172	R:R:D731	R:R:V732	8.76	No	No	0	3	4
173	R:R:L735	R:R:W734	9.11	No	Yes	0	9	8
174	R:R:L744	R:R:W734	4.56	No	Yes	0	8	8
175	R:R:F747	R:R:W734	7.02	Yes	Yes	1	8	8
176	R:R:L735	R:R:P743	6.57	No	No	0	9	8
177	R:R:K742	R:R:W737	9.28	No	No	0	7	6
178	R:R:L744	R:R:W737	3.42	No	No	0	8	6
179	R:R:L744	R:R:V748	4.47	No	No	0	8	7
180	R:R:L745	R:R:V749	4.47	No	No	0	8	7
181	R:R:I811	R:R:V748	4.61	No	No	1	5	7
182	R:R:P750	R:R:V749	3.53	No	No	0	9	7
183	R:R:I808	R:R:L752	7.14	No	No	0	7	8
184	R:R:L800	R:R:N758	20.6	No	No	0	9	9
185	R:R:F759	R:R:L763	4.87	No	No	0	4	4
186	R:R:F759	R:R:L802	3.65	No	No	0	4	7
187	R:R:L802	R:R:V762	5.96	No	No	0	7	8
188	R:R:L796	R:R:V765	4.47	Yes	No	0	9	9
189	R:R:T785	R:R:W770	6.06	No	No	0	7	6
190	R:R:V789	R:R:W770	14.71	No	No	0	8	6
191	R:R:A784	R:R:I787	3.25	No	No	0	6	4
192	R:R:K791	R:R:L841	4.23	No	No	0	8	5
193	R:R:L793	R:R:L794	4.15	No	No	0	7	6
194	R:R:L796	R:R:L800	5.54	Yes	No	0	9	9
195	R:R:P798	R:R:T797	3.5	No	No	0	9	9
196	R:R:L802	R:R:T797	4.42	No	No	0	7	9
197	R:R:F837	R:R:P798	4.33	No	No	0	8	9
198	R:R:I834	R:R:L799	4.28	No	No	0	9	6
199	R:R:N827	R:R:T803	5.85	No	No	0	9	9
200	R:R:F823	R:R:W804	6.01	Yes	Yes	1	9	9
201	R:R:N827	R:R:W804	16.95	No	Yes	1	9	9
202	R:R:Q830	R:R:W804	10.95	No	Yes	0	9	9
203	R:R:F806	R:R:I822	10.05	No	No	0	8	5
204	R:R:F806	R:R:L826	3.65	No	No	0	8	6
205	R:R:G807	R:R:T810	3.64	No	Yes	0	9	7
206	R:R:G809	R:R:I808	3.53	No	No	0	7	7
207	R:R:G809	R:R:W819	5.63	No	No	0	7	6
208	R:R:H820	R:R:T810	6.85	Yes	Yes	1	8	7
209	R:R:F823	R:R:T810	3.89	Yes	Yes	1	9	7
210	R:R:D813	R:R:N816	8.08	No	No	0	4	5
211	R:R:L817	R:R:N816	6.87	No	No	0	2	5
212	R:R:F823	R:R:N827	15.71	Yes	No	1	9	9
213	R:R:F832	R:R:F833	5.36	No	No	0	5	7
214	R:R:L835	R:R:L840	5.54	No	No	0	8	7
215	R:R:C836	R:R:F837	6.98	No	No	0	7	8
216	R:R:I839	R:R:L845	5.71	No	No	0	7	8
217	R:R:L841	R:R:R846	3.64	No	No	0	5	7
218	R:R:R846	R:R:S843	3.95	No	No	0	7	5
219	R:R:K844	R:R:L848	9.87	No	No	0	8	7
220	R:R:L849	R:R:L853	6.92	No	No	0	7	4
221	R:R:P723	R:R:Q722	3.16	No	No	0	8	7
222	R:R:I581	R:R:V821	3.07	Yes	No	0	4	7
223	R:R:I588	R:R:V584	3.07	No	No	0	9	3
224	R:R:F806	R:R:W819	3.01	No	No	0	8	6
225	R:R:L769	R:R:S792	3	No	No	0	7	8
226	R:R:L604	R:R:V628	2.98	No	No	0	8	7
227	R:R:L676	R:R:V757	2.98	No	No	0	7	7
228	R:R:L682	R:R:V761	2.98	No	No	0	9	8
229	R:R:L796	R:R:V762	2.98	Yes	No	0	9	8
230	R:R:L769	R:R:V765	2.98	No	No	0	7	9
231	R:R:L825	R:R:V821	2.98	No	No	0	5	7
232	R:R:L764	R:R:T767	2.95	No	No	0	7	4
233	R:R:L793	R:R:T797	2.95	No	No	0	7	9
234	R:R:I601	R:R:I605	2.94	No	No	0	5	6
235	R:R:D813	R:R:S814	2.94	No	No	0	4	5
236	R:R:D648	R:R:T649	2.89	No	No	0	5	3
237	R:R:F833	R:R:P798	2.89	No	No	0	7	9
238	R:R:P772	R:R:R771	2.88	No	No	0	7	8
239	R:R:I588	R:R:L825	2.85	No	No	0	9	5
240	R:R:I605	R:R:L609	2.85	No	No	0	6	4
241	R:R:I606	R:R:L849	2.85	No	No	0	8	7
242	R:R:I687	R:R:L688	2.85	No	No	0	6	6
243	R:R:I687	R:R:L764	2.85	No	No	0	6	7
244	R:R:I839	R:R:L840	2.85	No	No	0	7	7
245	R:R:Q722	R:R:T658	2.83	No	No	0	7	6
246	R:R:A659	R:R:F663	2.77	No	No	0	7	8
247	R:R:L682	R:R:L796	2.77	No	Yes	0	9	9
248	R:R:A784	R:R:R788	2.77	No	No	0	6	7
249	R:R:F672	R:R:V755	2.62	Yes	No	0	9	8
250	R:R:A660	R:R:W640	2.59	No	No	0	7	6
251	R:R:R788	R:R:T785	2.59	No	No	0	7	7
252	R:R:Q618	R:R:Q695	2.56	No	No	0	7	6
253	R:R:F673	R:R:I713	2.51	Yes	No	0	8	9
254	R:R:F673	R:R:L669	2.44	Yes	Yes	0	8	9
255	R:R:F829	R:R:L825	2.44	No	No	0	7	5
256	R:R:G708	R:R:P710	2.03	No	No	0	6	9
257	R:R:C733	R:R:G644	1.96	No	No	0	9	6
258	R:R:G592	R:R:V591	1.84	No	No	0	9	7
259	R:R:G702	R:R:V701	1.84	No	No	0	7	6
260	R:R:G805	R:R:V755	1.84	No	No	0	6	8
261	R:R:G790	R:R:V789	1.84	No	No	0	5	8
262	R:R:G809	R:R:V812	1.84	No	No	0	7	6
263	R:R:G838	R:R:I795	1.76	No	No	0	8	7
264	R:R:P578	R:R:T580	1.75	Yes	No	0	4	3
265	R:R:G838	R:R:M627	1.75	No	No	0	8	7
266	R:R:G706	R:R:L705	1.71	No	No	0	9	6
267	R:R:G790	R:R:L793	1.71	No	No	0	5	7
268	R:R:A683	R:R:V761	1.7	No	No	0	6	8
269	R:R:A818	R:R:V821	1.7	No	No	0	6	7
270	R:R:N652	R:R:P653	1.63	No	No	0	4	4
271	R:R:C657	R:R:K728	1.62	No	No	0	9	5
272	R:R:S579	R:R:T580	1.6	No	No	0	3	3
273	R:R:S617	R:R:T619	1.6	No	No	0	8	8
274	R:R:T646	R:R:V647	1.59	No	No	0	5	5
275	R:R:C704	R:R:L705	1.59	No	No	0	4	6
276	R:R:A694	R:R:L697	1.58	No	No	0	8	3
277	R:R:I686	R:R:V765	1.54	No	No	0	7	9
278	R:R:I716	R:R:V720	1.54	No	No	0	7	5
279	R:R:K616	R:R:S620	1.53	No	No	0	7	8
280	R:R:L697	R:R:V701	1.49	No	No	0	3	6
281	R:R:L766	R:R:V762	1.49	No	No	0	7	8
282	R:R:L766	R:R:V789	1.49	No	No	0	7	8
283	R:R:I712	R:R:I716	1.47	No	No	0	5	7
284	R:R:Q815	R:R:S814	1.44	No	No	0	3	5
285	R:R:K728	R:R:N725	1.4	No	No	0	5	4
286	R:R:D731	R:R:K730	1.38	No	No	0	3	2
287	R:R:K612	R:R:Q613	1.36	No	No	0	7	5
288	R:R:K844	R:R:Q847	1.36	No	No	0	8	6
289	R:R:I786	R:R:W770	1.17	No	No	0	6	6
290	R:R:F850	R:R:R846	1.07	No	No	0	3	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F569	5.74833	6	1	9
2	R:R:L572	5.3325	4	0	9
3	R:R:M573	4.85	6	1	9
4	R:R:P578	4.754	5	0	4
5	R:R:I581	4.22	4	0	4
6	R:R:F610	5.14	4	4	8
7	R:R:R624	5.608	5	0	9
8	R:R:D638	5.902	5	0	7
9	R:R:F662	6.34	4	1	8
10	R:R:H665	4.264	5	1	9
11	R:R:Y668	6.388	5	0	8
12	R:R:L669	4.46	5	1	9
13	R:R:F672	9.64	5	0	9
14	R:R:F673	4.9375	4	0	8
15	R:R:W674	9.26	7	2	9
16	R:R:M675	5.5975	4	0	9
17	R:R:Y684	10.135	4	0	8
18	R:R:R685	9.8425	4	0	8
19	R:R:F703	6.085	4	2	8
20	R:R:Y707	6.63	6	2	9
21	R:R:Y727	8.09571	7	1	9
22	R:R:W734	5.77143	7	1	8
23	R:R:F747	5.68	6	1	8
24	R:R:L796	3.94	4	0	9
25	R:R:W804	12.394	5	1	9
26	R:R:T810	4.395	4	1	7
27	R:R:H820	8.1525	4	1	8
28	R:R:F823	7.438	5	1	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L572	R:R:W734	10.6928	4.56	Yes	Yes	0	9	8
2	R:R:I571	R:R:W734	33.2411	4.7	No	Yes	0	7	8
3	R:R:I571	R:R:V732	19.8906	4.61	No	No	0	7	4
4	R:R:T567	R:R:V732	13.1566	4.76	No	No	0	9	4
5	R:R:F747	R:R:W734	31.587	7.02	Yes	Yes	1	8	8
6	R:R:F672	R:R:F747	43.1933	5.36	Yes	Yes	0	9	8
7	R:R:F672	R:R:W804	38.7016	23.05	Yes	Yes	0	9	9
8	R:R:H820	R:R:P578	51.8929	7.63	Yes	Yes	0	8	4
9	R:R:G807	R:R:T810	18.8387	3.64	No	Yes	0	9	7
10	R:R:G807	R:R:M573	20.3405	3.49	No	Yes	0	9	9
11	R:R:F747	R:R:M573	51.616	6.22	Yes	Yes	1	8	9
12	R:R:F823	R:R:T810	52.8687	3.89	Yes	Yes	1	9	7
13	R:R:F823	R:R:M573	21.4617	6.22	Yes	Yes	1	9	9
14	R:R:I571	R:R:R729	11.1219	11.27	No	No	0	7	5
15	R:R:L752	R:R:M573	17.8628	4.24	No	Yes	0	8	9
16	R:R:I581	R:R:P578	37.1098	5.08	Yes	Yes	0	4	4
17	R:R:I581	R:R:Q815	12.07	4.12	Yes	No	0	4	3
18	R:R:L825	R:R:V821	16.8039	2.98	No	No	0	5	7
19	R:R:I581	R:R:V821	21.4825	3.07	Yes	No	0	4	7
20	R:R:D638	R:R:Y668	11.108	4.6	Yes	Yes	0	7	8
21	R:R:F747	R:R:Y668	15.7035	7.22	Yes	Yes	0	8	8
22	R:R:F832	R:R:F833	56.8482	5.36	No	No	0	5	7
23	R:R:F833	R:R:P798	58.3777	2.89	No	No	0	7	9
24	R:R:P798	R:R:T797	62.6687	3.5	No	No	0	9	9
25	R:R:L802	R:R:T797	64.7726	4.42	No	No	0	7	9
26	R:R:L802	R:R:V762	69.0359	5.96	No	No	0	7	8
27	R:R:L796	R:R:V762	84.165	2.98	Yes	No	0	9	8
28	R:R:L796	R:R:L800	95.626	5.54	Yes	No	0	9	9
29	R:R:L678	R:R:L800	97.8407	4.15	No	No	0	8	9
30	R:R:C626	R:R:L678	98.9273	3.17	No	No	0	7	8
31	R:R:C626	R:R:W674	100	3.92	No	Yes	0	7	9
32	R:R:I630	R:R:W674	86.0959	3.52	No	Yes	0	8	9
33	R:R:I630	R:R:M675	86.0544	4.37	No	Yes	0	8	9
34	R:R:F672	R:R:M675	76.4205	7.46	Yes	Yes	0	9	9
35	R:R:F832	R:R:S599	53.7477	5.28	No	No	0	5	8
36	R:R:L835	R:R:S599	52.1766	7.51	No	No	0	8	8
37	R:R:L600	R:R:L634	11.3433	9.69	No	No	0	9	9
38	R:R:D638	R:R:L634	12.1808	10.86	Yes	No	0	7	9
39	R:R:I839	R:R:L840	47.595	2.85	No	No	0	7	7
40	R:R:L835	R:R:L840	48.993	5.54	No	No	0	8	7
41	R:R:L845	R:R:R624	25.8703	3.64	No	Yes	0	8	9
42	R:R:I839	R:R:L845	44.2522	5.71	No	No	0	7	8
43	R:R:F610	R:R:L849	13.5857	4.87	Yes	No	0	8	7
44	R:R:I606	R:R:L849	17.1084	2.85	No	No	0	8	7
45	R:R:I606	R:R:L845	18.7141	4.28	No	No	0	8	8
46	R:R:H621	R:R:I625	54.8827	9.28	No	No	0	6	7
47	R:R:I625	R:R:M699	56.6337	5.83	No	No	0	7	7
48	R:R:F703	R:R:M699	58.6269	3.73	Yes	No	0	8	7
49	R:R:F703	R:R:W674	35.6703	8.02	Yes	Yes	2	8	9
50	R:R:F703	R:R:Y707	24.5138	4.13	Yes	Yes	2	8	9
51	R:R:S670	R:R:Y707	36.3624	7.63	No	Yes	2	8	9
52	R:R:P710	R:R:S670	38.058	3.56	No	No	0	9	8
53	R:R:L669	R:R:P710	39.2622	3.28	Yes	No	0	9	9
54	R:R:F747	R:R:L669	24.5623	4.87	Yes	Yes	1	8	9
55	R:R:H665	R:R:L669	22.306	5.14	Yes	Yes	1	9	9
56	R:R:H665	R:R:W734	15.8212	3.17	Yes	Yes	1	9	8
57	R:R:L681	R:R:R685	26.0572	3.64	No	Yes	0	7	8
58	R:R:L681	R:R:T622	27.9396	5.9	No	No	0	7	7
59	R:R:Q695	R:R:T622	47.0552	4.25	No	No	0	6	7
60	R:R:H621	R:R:Q695	51.1523	7.42	No	No	0	6	6
61	R:R:M698	R:R:T622	17.1084	6.02	No	No	0	8	7
62	R:R:R623	R:R:R624	11.5787	5.33	No	Yes	0	9	9
63	R:R:F667	R:R:I636	24.0501	21.35	No	No	0	8	7
64	R:R:F666	R:R:F667	33.4418	15	No	No	0	7	8
65	R:R:F666	R:R:S714	34.0093	5.28	No	No	0	7	9
66	R:R:H665	R:R:S714	36.2309	4.18	Yes	No	0	9	9
67	R:R:I636	R:R:L632	23.7317	7.14	No	No	0	7	5
68	R:R:L632	R:R:Y707	25.5173	3.52	No	Yes	0	5	9
69	R:R:L671	R:R:M675	12.423	7.07	No	Yes	0	7	9
70	R:R:F663	R:R:F667	45.0619	7.5	No	No	0	8	8
71	R:R:F663	R:R:W640	41.2416	19.04	No	No	0	8	6
72	R:R:V643	R:R:W640	37.3659	6.13	No	No	0	8	6
73	R:R:G644	R:R:V643	35.4073	3.68	No	No	0	6	8
74	R:R:C733	R:R:G644	33.4348	1.96	No	No	0	9	6
75	R:R:C657	R:R:C733	31.4485	7.28	No	No	0	9	9
76	R:R:C657	R:R:V647	19.2401	3.42	No	No	0	9	5
77	R:R:V647	R:R:V656	15.0599	3.21	No	No	0	5	5
78	R:R:N652	R:R:V656	12.949	5.91	No	No	0	4	5
79	R:R:C657	R:R:K728	10.8243	1.62	No	No	0	9	5
80	R:R:H665	R:R:Y727	25.545	5.44	Yes	Yes	1	9	9
81	R:R:F673	R:R:L669	16.0772	2.44	Yes	Yes	0	8	9
82	R:R:M677	R:R:W674	11.4679	4.65	No	Yes	0	6	9
83	R:R:R685	R:R:Y684	13.3642	14.4	Yes	Yes	0	8	8
84	R:R:L688	R:R:Y684	17.4476	4.69	No	Yes	0	6	8
85	R:R:M693	R:R:Y684	12.7967	8.38	No	Yes	0	5	8
86	R:R:M693	R:R:M698	14.9561	7.22	No	No	0	5	8
87	R:R:I808	R:R:L752	15.6897	7.14	No	No	0	7	8
88	R:R:L766	R:R:V762	14.6861	1.49	No	No	0	7	8
89	R:R:L766	R:R:V789	13.0736	1.49	No	No	0	7	8
90	R:R:V789	R:R:W770	11.6133	14.71	No	No	0	8	6
91	R:R:G809	R:R:I808	13.4888	3.53	No	No	0	7	7
92	R:R:I687	R:R:L688	12.9628	2.85	No	No	0	6	6
93	R:R:H820	R:R:T810	60.3917	6.85	Yes	Yes	1	8	7
94	R:R:F823	R:R:W804	28.2303	6.01	Yes	Yes	1	9	9
95	R:R:W674	R:R:Y707	33.6217	12.54	Yes	Yes	2	9	9
96	R:R:F747	R:R:H665	36.57	3.39	Yes	Yes	1	8	9
97	R:R:L634	R:R:L671	10.7135	5.54	No	No	0	9	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7WY0_nogp

PDB Summary
PDB	7WY0_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.17
Number of Linked Nodes	261
Number of Links	290
Number of Hubs	28
Number of Links mediated by Hubs	109
Number of Communities	4
Number of Nodes involved in Communities	30
Number of Links involved in Communities	40

Path Summary
Number Of Nodes in MetaPath	98
Number Of Links MetaPath	97
Number of Shortest Paths	43160
Length Of Smallest Path	3
Average Path Length	14.7594
Length of Longest Path	39
Minimum Path Strength	1.505
Average Path Strength	5.77848
Maximum Path Strength	20
Minimum Path Correlation	0.7
Average Path Correlation	0.927767
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	50.5238
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	35.9235
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell surface receptor signaling pathway • regulation of lipid metabolic process • primary metabolic process • metabolic process • regulation of metabolic process • lipid metabolic process • regulation of primary metabolic process • developmental process • fat cell differentiation • cellular developmental process • cell differentiation • behavior • multicellular organismal process • system process • learning or memory • nervous system process • cognition • memory • nervous system development • cellular component organization • cellular component biogenesis • multicellular organism development • cell junction organization • cellular component assembly • cell junction assembly • anatomical structure development • synapse organization • cellular component organization or biogenesis • synapse assembly • system development • energy derivation by oxidation of organic compounds • energy reserve metabolic process • generation of precursor metabolites and energy • plasma membrane bounded cell projection organization • cell projection organization • cell development • neuron projection development • generation of neurons • neurogenesis • neuron differentiation • neuron development • membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • cytoplasmic vesicle • organelle • intracellular vesicle • cytoplasm • intracellular membrane-bounded organelle • vesicle • membrane • extracellular region • cell periphery • plasma membrane • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular space • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q5T601
Sequence	>7WY0_nogp_Chain_R T S F S I L M S P F V P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W K Q I K K S Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V D T T V N P S G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L V F H H M A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q P S N T Y K R K D V C W L N W S N G S K P L L A F V V P A L A I V A V N F V V V L L V L T K L W R P A T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S Q N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L R Q L L F N K L S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8G2Y	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC	chim(Gs-CtGq)/β1/γ2	3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	8G2Y (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC		3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	7WU3	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gs/β1/γ2	3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU3 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WXU	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXU (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1L-G13)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-G12)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	Gi1/β1/γ2	3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4

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