psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:T567	R:R:Y590	7.49	No	No	0	9	5
2	R:R:A645	R:R:T567	3.36	No	No	0	7	9
3	R:R:S568	R:R:V577	3.23	No	Yes	0	9	3
4	R:R:S568	R:R:V585	3.23	No	No	0	9	8
5	R:R:F569	R:R:L572	4.87	Yes	No	0	9	9
6	R:R:F569	R:R:T589	5.19	Yes	No	1	9	9
7	R:R:F569	R:R:L593	3.65	Yes	Yes	1	9	8
8	R:R:F569	R:R:Y668	2.06	Yes	Yes	0	9	8
9	R:R:F569	R:R:F823	3.22	Yes	Yes	1	9	9
10	R:R:S570	R:R:S574	6.52	No	Yes	0	9	9
11	R:R:S570	R:R:T810	4.8	No	No	1	9	7
12	R:R:H820	R:R:S570	9.76	Yes	No	1	8	9
13	R:R:I571	R:R:S574	3.1	No	Yes	0	7	9
14	R:R:F641	R:R:I571	5.02	No	No	0	9	7
15	R:R:F641	R:R:L572	3.65	No	No	0	9	9
16	R:R:L572	R:R:W734	5.69	No	Yes	0	9	8
17	R:R:G807	R:R:M573	3.49	No	No	1	9	9
18	R:R:F823	R:R:M573	3.73	Yes	No	1	9	9
19	R:R:P575	R:R:S574	1.78	No	Yes	0	6	9
20	R:R:S574	R:R:V577	4.85	Yes	Yes	0	9	3
21	R:R:P575	R:R:W737	10.81	No	No	0	6	6
22	R:R:I811	R:R:P575	1.69	No	No	0	5	6
23	R:R:F576	R:R:P578	7.22	No	Yes	0	3	4
24	R:R:P578	R:R:V577	3.53	Yes	Yes	1	4	3
25	R:R:H820	R:R:V577	4.15	Yes	Yes	1	8	3
26	R:R:P578	R:R:T580	1.75	Yes	No	1	4	3
27	R:R:P578	R:R:S814	1.78	Yes	No	0	4	5
28	R:R:H820	R:R:P578	3.05	Yes	Yes	1	8	4
29	R:R:I581	R:R:T580	4.56	No	No	1	4	3
30	R:R:Q815	R:R:T580	2.83	No	No	1	3	3
31	R:R:I581	R:R:V584	3.07	No	No	0	4	3
32	R:R:I581	R:R:Q815	13.72	No	No	1	4	3
33	R:R:F582	R:R:P583	2.89	No	No	0	1	1
34	R:R:V585	R:R:V821	3.21	No	No	0	8	7
35	R:R:L593	R:R:T589	2.95	Yes	No	1	8	9
36	R:R:G592	R:R:V591	1.84	No	No	0	9	7
37	R:R:A828	R:R:G592	1.95	No	No	0	8	9
38	R:R:F829	R:R:G592	4.52	No	No	0	7	9
39	R:R:G594	R:R:L593	1.71	No	Yes	0	5	8
40	R:R:D638	R:R:L593	2.71	Yes	Yes	0	7	8
41	R:R:I642	R:R:L593	2.85	No	Yes	0	8	8
42	R:R:F832	R:R:I595	3.77	No	No	0	5	7
43	R:R:G598	R:R:I597	3.53	No	Yes	0	3	7
44	R:R:I597	R:R:L635	2.85	Yes	No	0	7	8
45	R:R:D638	R:R:I597	4.2	Yes	Yes	0	7	7
46	R:R:G598	R:R:I601	3.53	No	No	0	3	5
47	R:R:F832	R:R:S599	3.96	No	No	0	5	8
48	R:R:L835	R:R:S599	6.01	Yes	No	0	8	8
49	R:R:L600	R:R:L634	4.15	Yes	Yes	0	9	9
50	R:R:L600	R:R:L635	2.77	Yes	No	0	9	8
51	R:R:G831	R:R:L600	3.42	No	Yes	0	9	9
52	R:R:L602	R:R:L835	2.77	No	Yes	0	6	8
53	R:R:C603	R:R:L835	6.35	No	Yes	0	7	8
54	R:R:C603	R:R:I839	3.27	No	No	0	7	7
55	R:R:I606	R:R:L845	2.85	No	No	0	8	8
56	R:R:I606	R:R:L849	5.71	No	No	0	8	7
57	R:R:E607	R:R:R624	6.98	No	Yes	0	9	9
58	R:R:E607	R:R:V628	5.7	No	No	0	9	7
59	R:R:F610	R:R:L609	17.05	No	No	0	8	4
60	R:R:F610	R:R:L848	6.09	No	No	0	8	7
61	R:R:F610	R:R:K852	4.96	No	No	0	8	4
62	R:R:I614	R:R:W611	4.7	No	No	5	7	9
63	R:R:R624	R:R:W611	2	Yes	No	5	9	9
64	R:R:K612	R:R:Q613	8.14	No	No	0	7	5
65	R:R:L848	R:R:Q613	2.66	No	No	0	7	5
66	R:R:I614	R:R:R624	3.76	No	Yes	5	7	9
67	R:R:H621	R:R:K615	10.48	No	No	0	6	8
68	R:R:S617	R:R:S620	3.26	No	No	0	8	8
69	R:R:Q618	R:R:Q695	11.52	No	No	0	7	6
70	R:R:M698	R:R:Q618	6.8	No	No	0	8	7
71	R:R:R685	R:R:T619	14.23	No	No	0	8	8
72	R:R:H621	R:R:I625	2.65	No	No	6	6	7
73	R:R:H621	R:R:M699	2.63	No	No	6	6	7
74	R:R:C626	R:R:T622	1.69	No	No	0	7	7
75	R:R:L681	R:R:T622	2.95	No	No	0	7	7
76	R:R:M698	R:R:T622	4.52	No	No	0	8	7
77	R:R:R623	R:R:R624	3.2	No	Yes	0	9	9
78	R:R:L845	R:R:R624	7.29	No	Yes	0	8	9
79	R:R:I625	R:R:M699	2.92	No	No	6	7	7
80	R:R:C626	R:R:W674	2.61	No	Yes	0	7	9
81	R:R:C626	R:R:L678	3.17	No	No	0	7	8
82	R:R:L799	R:R:M627	5.65	No	No	0	6	7
83	R:R:N629	R:R:W674	22.6	No	Yes	2	9	9
84	R:R:N629	R:R:Y707	4.65	No	No	2	9	9
85	R:R:I630	R:R:L671	2.85	No	No	0	8	7
86	R:R:I630	R:R:M675	2.92	No	No	0	8	9
87	R:R:I636	R:R:L632	4.28	No	No	0	7	5
88	R:R:S633	R:R:S670	4.89	No	No	0	8	8
89	R:R:D638	R:R:L634	4.07	Yes	Yes	0	7	9
90	R:R:L634	R:R:L671	2.77	Yes	No	0	9	7
91	R:R:L634	R:R:Q830	2.66	Yes	Yes	0	9	9
92	R:R:F667	R:R:I636	13.82	No	No	0	8	7
93	R:R:A637	R:R:Y668	9.34	No	Yes	0	9	8
94	R:R:D638	R:R:Y668	3.45	Yes	Yes	0	7	8
95	R:R:V643	R:R:W640	6.13	No	Yes	0	8	6
96	R:R:A660	R:R:W640	2.59	No	Yes	0	7	6
97	R:R:F663	R:R:W640	15.03	No	Yes	0	8	6
98	R:R:T664	R:R:W640	2.43	No	Yes	0	7	6
99	R:R:G644	R:R:V643	3.68	No	No	0	6	8
100	R:R:G644	R:R:V647	1.84	No	No	0	6	5
101	R:R:A660	R:R:G644	1.95	No	No	0	7	6
102	R:R:C657	R:R:V647	1.71	Yes	No	3	9	5
103	R:R:C733	R:R:V647	3.42	Yes	No	3	9	5
104	R:R:D648	R:R:T650	11.56	No	No	0	5	3
105	R:R:C657	R:R:T649	1.69	Yes	No	3	9	3
106	R:R:C733	R:R:T649	1.69	Yes	No	3	9	3
107	R:R:N652	R:R:P653	6.52	No	No	0	4	4
108	R:R:G655	R:R:S654	3.71	No	No	0	3	4
109	R:R:A660	R:R:V656	1.7	No	No	0	7	5
110	R:R:C657	R:R:K728	4.85	Yes	No	0	9	5
111	R:R:C657	R:R:C733	7.28	Yes	Yes	3	9	9
112	R:R:Q722	R:R:T658	4.25	No	No	0	7	6
113	R:R:V661	R:R:Y727	8.83	No	Yes	0	8	9
114	R:R:C733	R:R:V661	1.71	Yes	No	0	9	8
115	R:R:F662	R:R:F663	5.36	Yes	No	0	8	8
116	R:R:F662	R:R:S714	3.96	Yes	No	0	8	9
117	R:R:F662	R:R:I718	10.05	Yes	No	7	8	7
118	R:R:F662	R:R:Y727	3.09	Yes	Yes	7	8	9
119	R:R:T664	R:R:Y668	2.5	No	Yes	0	7	8
120	R:R:T664	R:R:W734	8.49	No	Yes	0	7	8
121	R:R:H665	R:R:L669	5.14	No	Yes	0	9	9
122	R:R:F747	R:R:H665	2.26	No	No	0	8	9
123	R:R:F666	R:R:F667	7.5	Yes	No	0	7	8
124	R:R:F666	R:R:P710	5.78	Yes	Yes	0	7	9
125	R:R:F666	R:R:L711	2.44	Yes	No	0	7	7
126	R:R:F666	R:R:S714	5.28	Yes	No	0	7	9
127	R:R:F747	R:R:Y668	4.13	No	Yes	0	8	8
128	R:R:F673	R:R:L669	2.44	No	Yes	0	8	9
129	R:R:L669	R:R:P710	3.28	Yes	Yes	0	9	9
130	R:R:I713	R:R:L669	2.85	No	Yes	0	9	9
131	R:R:L669	R:R:P750	1.64	Yes	No	0	9	9
132	R:R:P710	R:R:S670	1.78	Yes	No	0	9	8
133	R:R:F672	R:R:L671	2.44	Yes	No	0	9	7
134	R:R:A751	R:R:F672	6.93	No	Yes	0	9	9
135	R:R:F672	R:R:I754	5.02	Yes	No	0	9	9
136	R:R:F672	R:R:W804	6.01	Yes	No	0	9	9
137	R:R:C709	R:R:F673	4.19	Yes	No	0	8	8
138	R:R:M677	R:R:W674	3.49	No	Yes	0	6	9
139	R:R:G702	R:R:W674	2.81	No	Yes	0	7	9
140	R:R:F703	R:R:W674	3.01	No	Yes	2	8	9
141	R:R:G706	R:R:W674	4.22	No	Yes	0	9	9
142	R:R:W674	R:R:Y707	3.86	Yes	No	2	9	9
143	R:R:G801	R:R:M675	1.75	No	No	0	9	9
144	R:R:I754	R:R:L676	2.85	No	No	0	9	7
145	R:R:L705	R:R:M677	4.24	No	No	0	6	6
146	R:R:G679	R:R:L678	1.71	No	No	0	9	8
147	R:R:L678	R:R:L800	4.15	No	No	0	8	9
148	R:R:G679	R:R:N758	1.7	No	No	0	9	9
149	R:R:G679	R:R:V761	1.84	No	No	0	9	8
150	R:R:L681	R:R:R685	4.86	No	No	0	7	8
151	R:R:L682	R:R:V761	2.98	No	No	0	9	8
152	R:R:R685	R:R:Y684	5.14	No	Yes	0	8	8
153	R:R:L688	R:R:Y684	3.52	No	Yes	0	6	8
154	R:R:H691	R:R:Y684	8.71	No	Yes	8	7	8
155	R:R:M693	R:R:Y684	4.79	No	Yes	8	5	8
156	R:R:I686	R:R:L764	2.85	No	No	0	7	7
157	R:R:H691	R:R:M693	3.94	No	No	8	7	5
158	R:R:L697	R:R:M693	4.24	No	No	0	3	5
159	R:R:A694	R:R:H696	5.85	No	No	0	8	5
160	R:R:M699	R:R:Q695	6.8	No	No	0	7	6
161	R:R:G702	R:R:V701	1.84	No	No	0	7	6
162	R:R:C704	R:R:V701	1.71	No	No	0	4	6
163	R:R:F703	R:R:Y707	4.13	No	No	2	8	9
164	R:R:G708	R:R:P710	2.03	No	Yes	0	6	9
165	R:R:C709	R:R:P710	1.88	Yes	Yes	0	8	9
166	R:R:C709	R:R:I713	1.64	Yes	No	0	8	9
167	R:R:L711	R:R:V715	2.98	No	No	0	7	6
168	R:R:I712	R:R:I716	2.94	No	No	0	5	7
169	R:R:P743	R:R:T717	1.75	Yes	No	0	8	9
170	R:R:A746	R:R:T717	1.68	No	No	0	9	9
171	R:R:I718	R:R:Y727	4.84	No	Yes	7	7	9
172	R:R:T721	R:R:T726	4.71	No	No	0	9	4
173	R:R:T721	R:R:Y727	3.75	No	Yes	0	9	9
174	R:R:P743	R:R:T721	1.75	Yes	No	0	8	9
175	R:R:P723	R:R:Q722	3.16	No	No	0	8	7
176	R:R:S724	R:R:T726	3.2	No	No	0	3	4
177	R:R:S741	R:R:T726	6.4	No	No	0	8	4
178	R:R:D731	R:R:R729	4.76	No	No	9	3	5
179	R:R:R729	R:R:V732	3.92	No	No	9	5	4
180	R:R:N736	R:R:R729	8.44	No	No	0	8	5
181	R:R:D731	R:R:V732	5.84	No	No	9	3	4
182	R:R:L735	R:R:W734	12.53	No	Yes	4	9	8
183	R:R:L744	R:R:W734	3.42	No	Yes	4	8	8
184	R:R:L735	R:R:P743	3.28	No	Yes	0	9	8
185	R:R:L735	R:R:L744	2.77	No	No	4	9	8
186	R:R:K742	R:R:W737	9.28	No	No	0	7	6
187	R:R:P743	R:R:S741	1.78	Yes	No	0	8	8
188	R:R:K742	R:R:P743	1.67	No	Yes	0	7	8
189	R:R:L745	R:R:V749	2.98	No	No	0	8	7
190	R:R:L752	R:R:V748	2.98	No	No	0	8	7
191	R:R:P750	R:R:V749	3.53	No	No	0	9	7
192	R:R:G805	R:R:L752	1.71	No	No	0	6	8
193	R:R:L800	R:R:N758	12.36	No	No	0	9	9
194	R:R:F759	R:R:L763	6.09	No	No	0	4	4
195	R:R:F759	R:R:L802	2.44	No	No	0	4	7
196	R:R:L769	R:R:V765	2.98	No	No	0	7	9
197	R:R:L766	R:R:V789	4.47	No	Yes	0	7	8
198	R:R:K768	R:R:T767	7.51	No	No	0	8	4
199	R:R:K768	R:R:R771	2.48	No	No	0	8	8
200	R:R:L769	R:R:S792	3	No	No	0	7	8
201	R:R:T785	R:R:W770	6.06	No	No	0	7	6
202	R:R:P772	R:R:T785	1.75	No	No	0	7	7
203	R:R:P772	R:R:R788	2.88	No	No	0	7	7
204	R:R:G790	R:R:V789	1.84	No	Yes	0	5	8
205	R:R:S792	R:R:V789	3.23	No	Yes	0	8	8
206	R:R:K791	R:R:L841	2.82	No	No	0	8	5
207	R:R:F837	R:R:L794	7.31	Yes	No	0	8	6
208	R:R:I795	R:R:L796	2.85	No	No	0	7	9
209	R:R:I795	R:R:L841	2.85	No	No	0	7	5
210	R:R:P798	R:R:T797	5.25	No	No	0	9	9
211	R:R:F833	R:R:P798	2.89	No	No	0	7	9
212	R:R:I834	R:R:P798	1.69	No	No	0	9	9
213	R:R:I834	R:R:L799	2.85	No	No	0	9	6
214	R:R:G801	R:R:Q830	1.64	No	Yes	0	9	9
215	R:R:N827	R:R:T803	5.85	Yes	No	0	9	9
216	R:R:N827	R:R:W804	6.78	Yes	No	0	9	9
217	R:R:Q830	R:R:W804	6.57	Yes	No	0	9	9
218	R:R:F806	R:R:L826	2.44	No	No	0	8	6
219	R:R:G807	R:R:T810	3.64	No	No	1	9	7
220	R:R:F823	R:R:G807	3.01	Yes	No	1	9	9
221	R:R:G809	R:R:I808	1.76	No	No	0	7	7
222	R:R:G809	R:R:V812	1.84	No	No	0	7	6
223	R:R:G809	R:R:W819	2.81	No	No	0	7	6
224	R:R:H820	R:R:T810	2.74	Yes	No	1	8	7
225	R:R:I811	R:R:V812	6.14	No	No	0	5	6
226	R:R:D813	R:R:S814	2.94	No	No	0	4	5
227	R:R:D813	R:R:N816	14.81	No	No	0	4	5
228	R:R:N816	R:R:W819	3.39	No	No	0	5	6
229	R:R:L817	R:R:W819	3.42	No	No	0	2	6
230	R:R:A818	R:R:V821	1.7	No	No	0	6	7
231	R:R:A818	R:R:I822	6.5	No	No	0	6	5
232	R:R:F823	R:R:N827	12.08	Yes	Yes	0	9	9
233	R:R:L825	R:R:L826	2.77	No	No	0	5	6
234	R:R:L826	R:R:N827	2.75	No	Yes	0	6	9
235	R:R:G831	R:R:Q830	1.64	No	Yes	0	9	9
236	R:R:G831	R:R:I834	1.76	No	No	0	9	9
237	R:R:F833	R:R:F837	6.43	No	Yes	0	7	8
238	R:R:L835	R:R:L840	2.77	Yes	No	0	8	7
239	R:R:C836	R:R:F837	5.59	No	Yes	0	7	8
240	R:R:D842	R:R:L845	4.07	No	No	0	9	8
241	R:R:K844	R:R:L848	5.64	No	No	0	8	7
242	R:R:F850	R:R:R846	3.21	No	No	0	3	7
243	R:R:F850	R:R:L849	2.44	No	No	0	3	7
244	R:R:N736	R:R:P743	1.63	No	Yes	0	8	8
245	R:R:A824	R:R:I588	1.62	No	No	0	8	9
246	R:R:A683	R:R:I687	1.62	No	No	0	6	6
247	R:R:C603	R:R:L600	1.59	No	Yes	0	7	9
248	R:R:T650	R:R:V651	1.59	No	No	0	3	1
249	R:R:C709	R:R:L705	1.59	Yes	No	0	8	6
250	R:R:A828	R:R:L593	1.58	No	Yes	0	8	8
251	R:R:I597	R:R:V639	1.54	Yes	No	0	7	6
252	R:R:I636	R:R:V639	1.54	No	No	0	7	6
253	R:R:I716	R:R:V715	1.54	No	No	0	7	6
254	R:R:I716	R:R:V720	1.54	No	No	0	7	5
255	R:R:I811	R:R:V748	1.54	No	No	0	5	7
256	R:R:K844	R:R:S843	1.53	No	No	0	8	5
257	R:R:I786	R:R:T785	1.52	No	No	0	6	7
258	R:R:F837	R:R:G838	1.51	Yes	No	0	8	8
259	R:R:L793	R:R:S792	1.5	No	No	0	7	8
260	R:R:N652	R:R:S654	1.49	No	No	0	4	4
261	R:R:L752	R:R:V755	1.49	No	No	0	8	8
262	R:R:L766	R:R:V762	1.49	No	Yes	0	7	8
263	R:R:L793	R:R:V762	1.49	No	Yes	0	7	8
264	R:R:L800	R:R:V762	1.49	No	Yes	0	9	8
265	R:R:L802	R:R:V762	1.49	No	Yes	0	7	8
266	R:R:N629	R:R:V628	1.48	No	No	0	9	7
267	R:R:D638	R:R:S596	1.47	Yes	No	0	7	9
268	R:R:I601	R:R:I605	1.47	No	No	0	5	6
269	R:R:D842	R:R:S843	1.47	No	No	0	9	5
270	R:R:I686	R:R:K768	1.45	No	No	0	7	8
271	R:R:P772	R:R:R771	1.44	No	No	0	7	8
272	R:R:L604	R:R:L635	1.38	No	No	0	8	8
273	R:R:L682	R:R:L796	1.38	No	No	0	9	9
274	R:R:I718	R:R:Q722	1.37	No	No	0	7	7
275	R:R:P583	R:R:W587	1.35	No	No	0	1	4
276	R:R:H696	R:R:L697	1.29	No	No	0	5	3
277	R:R:F829	R:R:I588	1.26	No	No	0	7	9
278	R:R:T646	R:R:Y590	1.25	No	No	0	5	5
279	R:R:V789	R:R:W770	1.23	Yes	No	0	8	6
280	R:R:K586	R:R:Y590	1.19	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F569	3.798	5	1	9
2	R:R:S574	4.0625	4	0	9
3	R:R:V577	3.94	4	1	3
4	R:R:P578	3.466	5	1	4
5	R:R:L593	2.575	6	1	8
6	R:R:I597	3.03	4	0	7
7	R:R:L600	2.9825	4	0	9
8	R:R:R624	4.646	5	5	9
9	R:R:L634	3.4125	4	0	9
10	R:R:D638	3.18	5	0	7
11	R:R:W640	6.545	4	0	6
12	R:R:C657	3.8825	4	3	9
13	R:R:F662	5.615	4	7	8
14	R:R:F666	5.25	4	0	7
15	R:R:Y668	4.296	5	0	8
16	R:R:L669	3.07	5	0	9
17	R:R:F672	5.1	4	0	9
18	R:R:W674	6.08571	7	2	9
19	R:R:Y684	5.54	4	8	8
20	R:R:C709	2.325	4	0	8
21	R:R:P710	2.95	5	0	9
22	R:R:Y727	5.1275	4	7	9
23	R:R:C733	3.525	4	3	9
24	R:R:W734	7.5325	4	4	8
25	R:R:P743	1.97667	6	0	8
26	R:R:V762	1.49	4	0	8
27	R:R:V789	2.6925	4	0	8
28	R:R:H820	4.925	4	1	8
29	R:R:F823	5.51	4	1	9
30	R:R:N827	6.865	4	0	9
31	R:R:Q830	3.1275	4	0	9
32	R:R:L835	4.475	4	0	8
33	R:R:F837	5.21	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F569	R:R:L572	13.2676	4.87	Yes	No	0	9	9
2	R:R:F641	R:R:L572	12.0522	3.65	No	No	0	9	9
3	R:R:F641	R:R:I571	10.9706	5.02	No	No	0	9	7
4	R:R:S568	R:R:V577	10.988	3.23	No	Yes	0	9	3
5	R:R:F569	R:R:F823	26.922	3.22	Yes	Yes	1	9	9
6	R:R:F823	R:R:G807	22.2087	3.01	Yes	No	1	9	9
7	R:R:G807	R:R:T810	21.1939	3.64	No	No	1	9	7
8	R:R:H820	R:R:T810	18.0536	2.74	Yes	No	1	8	7
9	R:R:F569	R:R:L593	12.7704	3.65	Yes	Yes	1	9	8
10	R:R:F569	R:R:Y668	41.9836	2.06	Yes	Yes	0	9	8
11	R:R:A828	R:R:G592	10.392	1.95	No	No	0	8	9
12	R:R:A828	R:R:L593	12.4535	1.58	No	Yes	0	8	8
13	R:R:D638	R:R:L593	12.6832	2.71	Yes	Yes	0	7	8
14	R:R:D638	R:R:Y668	51.3492	3.45	Yes	Yes	0	7	8
15	R:R:C603	R:R:L835	10.1884	6.35	No	Yes	0	7	8
16	R:R:C603	R:R:L600	13.4014	1.59	No	Yes	0	7	9
17	R:R:L600	R:R:L634	21.8365	4.15	Yes	Yes	0	9	9
18	R:R:D638	R:R:L634	43.0827	4.07	Yes	Yes	0	7	9
19	R:R:L634	R:R:Q830	15.3786	2.66	Yes	Yes	0	9	9
20	R:R:F823	R:R:N827	10.2088	12.08	Yes	Yes	0	9	9
21	R:R:G831	R:R:L600	14.7883	3.42	No	Yes	0	9	9
22	R:R:G831	R:R:Q830	12.8983	1.64	No	Yes	0	9	9
23	R:R:L845	R:R:R624	19.8854	7.29	No	Yes	0	8	9
24	R:R:E607	R:R:R624	25.3751	6.98	No	Yes	0	9	9
25	R:R:E607	R:R:V628	26.6399	5.7	No	No	0	9	7
26	R:R:N629	R:R:V628	28.0211	1.48	No	No	0	9	7
27	R:R:N629	R:R:W674	29.2713	22.6	No	Yes	2	9	9
28	R:R:M677	R:R:W674	97.9676	3.49	No	Yes	0	6	9
29	R:R:L705	R:R:M677	98.9794	4.24	No	No	0	6	6
30	R:R:C709	R:R:L705	100	1.59	Yes	No	0	8	6
31	R:R:C709	R:R:F673	27.1807	4.19	Yes	No	0	8	8
32	R:R:F673	R:R:L669	27.3814	2.44	No	Yes	0	8	9
33	R:R:H665	R:R:L669	81.9813	5.14	No	Yes	0	9	9
34	R:R:F747	R:R:H665	81.644	2.26	No	No	0	8	9
35	R:R:F747	R:R:Y668	81.3358	4.13	No	Yes	0	8	8
36	R:R:C709	R:R:P710	47.1418	1.88	Yes	Yes	0	8	9
37	R:R:L669	R:R:P710	29.3702	3.28	Yes	Yes	0	9	9
38	R:R:C709	R:R:I713	27.1807	1.64	Yes	No	0	8	9
39	R:R:I713	R:R:L669	27.3814	2.85	No	Yes	0	9	9
40	R:R:K844	R:R:S843	10.1593	1.53	No	No	0	8	5
41	R:R:D842	R:R:S843	11.6074	1.47	No	No	0	9	5
42	R:R:D842	R:R:L845	13.0495	4.07	No	No	0	9	8
43	R:R:M698	R:R:T622	10.1215	4.52	No	No	0	8	7
44	R:R:C626	R:R:T622	25.4303	1.69	No	No	0	7	7
45	R:R:C626	R:R:W674	67.0708	2.61	No	Yes	0	7	9
46	R:R:L681	R:R:R685	13.0117	4.86	No	No	0	7	8
47	R:R:L681	R:R:T622	14.3057	2.95	No	No	0	7	7
48	R:R:C626	R:R:L678	43.6468	3.17	No	No	0	7	8
49	R:R:G831	R:R:I834	23.5665	1.76	No	No	0	9	9
50	R:R:F666	R:R:S714	13.8899	5.28	Yes	No	0	7	9
51	R:R:F662	R:R:S714	13.7823	3.96	Yes	No	0	8	9
52	R:R:F662	R:R:Y727	10.6565	3.09	Yes	Yes	7	8	9
53	R:R:G679	R:R:L678	11.2933	1.71	No	No	0	9	8
54	R:R:L678	R:R:L800	31.8708	4.15	No	No	0	8	9
55	R:R:R685	R:R:Y684	10.1274	5.14	No	Yes	0	8	8
56	R:R:P772	R:R:T785	10.2553	1.75	No	No	0	7	7
57	R:R:T785	R:R:W770	13.1775	6.06	No	No	0	7	6
58	R:R:V789	R:R:W770	14.6255	1.23	Yes	No	0	8	6
59	R:R:L766	R:R:V789	17.2337	4.47	No	Yes	0	7	8
60	R:R:L766	R:R:V762	18.6555	1.49	No	Yes	0	7	8
61	R:R:L800	R:R:V762	29.5505	1.49	No	Yes	0	9	8
62	R:R:F833	R:R:P798	11.7033	2.89	No	No	0	7	9
63	R:R:I834	R:R:P798	16.466	1.69	No	No	0	9	9
64	R:R:H820	R:R:P578	10.6391	3.05	Yes	Yes	1	8	4
65	R:R:T664	R:R:Y668	13.1542	2.5	No	Yes	0	7	8
66	R:R:F666	R:R:P710	21.5021	5.78	Yes	Yes	0	7	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7WXW_nogp

PDB Summary
PDB	7WXW_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	1.64
Number of Linked Nodes	251
Number of Links	280
Number of Hubs	33
Number of Links mediated by Hubs	127
Number of Communities	9
Number of Nodes involved in Communities	40
Number of Links involved in Communities	46

Path Summary
Number Of Nodes in MetaPath	67
Number Of Links MetaPath	66
Number of Shortest Paths	54433
Length Of Smallest Path	3
Average Path Length	16.041
Length of Longest Path	33
Minimum Path Strength	1.22
Average Path Strength	3.8441
Maximum Path Strength	13.41
Minimum Path Correlation	0.7
Average Path Correlation	0.931575
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	49.4503
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.922
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cell surface receptor signaling pathway • regulation of lipid metabolic process • primary metabolic process • metabolic process • regulation of metabolic process • lipid metabolic process • regulation of primary metabolic process • developmental process • fat cell differentiation • cellular developmental process • cell differentiation • behavior • multicellular organismal process • system process • learning or memory • nervous system process • cognition • memory • nervous system development • cellular component organization • cellular component biogenesis • multicellular organism development • cell junction organization • cellular component assembly • cell junction assembly • anatomical structure development • synapse organization • cellular component organization or biogenesis • synapse assembly • system development • energy derivation by oxidation of organic compounds • energy reserve metabolic process • generation of precursor metabolites and energy • plasma membrane bounded cell projection organization • cell projection organization • cell development • neuron projection development • generation of neurons • neurogenesis • neuron differentiation • neuron development • cytoplasmic vesicle • intracellular vesicle
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q5T601
Sequence	>7WXW_nogp_Chain_R T S F S I L M S P F V P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W K Q I K K S Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V D T T V N P S G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L V F H H M A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q P S N T Y K R K D V C W L N W S N G S K P L L A F V V P A L A I V A V N F V V V L L V L T K L W R P A T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S Q N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L R Q L L F N K L S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7WU3	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gs/β1/γ2	3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU3 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.1	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU4 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3.4	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/β1/γ2	3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU5 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G		3	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WXU	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXU (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.85	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WXW (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.84	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1L-G13)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WY0 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-G12)/β1/γ2	2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7WZ7 (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		2.83	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	Gi1/β1/γ2	3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	7X2V (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-		3.09	2022-09-28	doi.org/10.1038/s41467-022-33173-4
	8G2Y	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC	chim(Gs-CtGq)/β1/γ2	3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7
	8G2Y (No Gprot)	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC		3.44	2023-05-10	doi.org/10.1038/s41467-023-38083-7

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7WXW_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.