Color | ConSurf Grade |
No Conservation data available | |
1 | |
2 | |
3 | |
4 | |
5 | |
6 | |
7 | |
8 | |
9 |
Index: link id, click on each number to highlight the corresponding link in the 3D visualization.
Node1 Node2: the two nodes of the corresponding link.
Int. Strength: the interaction strength between the two nodes.
Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".
Community: the id of the community the link belong to, otherwise 0.
ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.
Index | Node1 | Node2 | Int. Strength | Hub1? | Hub2? | Community | ConSurf1 | ConSurf2 |
---|---|---|---|---|---|---|---|---|
1 | R:R:I128 | R:R:M123 | 4.37 | No | No | 0 | 2 | 3 |
2 | R:R:M123 | R:R:Q131 | 8.16 | No | No | 0 | 3 | 3 |
3 | R:R:D124 | R:R:E127 | 3.9 | No | No | 0 | 2 | 1 |
4 | R:R:E127 | R:R:V130 | 4.28 | No | No | 0 | 1 | 1 |
5 | R:R:E133 | R:R:K136 | 8.1 | No | No | 0 | 2 | 2 |
6 | R:R:F141 | R:R:M137 | 7.46 | No | No | 0 | 6 | 4 |
7 | R:R:F383 | R:R:Y138 | 8.25 | No | No | 0 | 5 | 5 |
8 | R:R:F141 | R:R:M144 | 6.22 | No | No | 0 | 6 | 6 |
9 | R:R:F141 | R:R:F383 | 7.5 | No | No | 0 | 6 | 5 |
10 | R:R:F387 | R:R:M144 | 4.98 | No | No | 0 | 5 | 6 |
11 | R:R:T146 | R:R:Y145 | 4.99 | No | No | 1 | 7 | 7 |
12 | R:R:Y145 | R:R:Y149 | 3.97 | No | Yes | 1 | 7 | 8 |
13 | R:R:D195 | R:R:Y145 | 5.75 | Yes | No | 1 | 7 | 7 |
14 | R:R:D195 | R:R:T146 | 7.23 | Yes | No | 1 | 7 | 7 |
15 | R:R:L151 | R:R:V147 | 2.98 | No | No | 0 | 5 | 5 |
16 | R:R:G148 | R:R:S390 | 3.71 | No | No | 1 | 7 | 9 |
17 | R:R:F391 | R:R:G148 | 9.03 | No | No | 1 | 7 | 7 |
18 | R:R:K187 | R:R:Y149 | 5.97 | Yes | Yes | 1 | 8 | 8 |
19 | R:R:A188 | R:R:Y149 | 4 | No | Yes | 0 | 8 | 8 |
20 | R:R:V191 | R:R:Y149 | 12.62 | No | Yes | 0 | 7 | 8 |
21 | R:R:S389 | R:R:Y149 | 3.82 | No | Yes | 1 | 6 | 8 |
22 | R:R:S390 | R:R:Y149 | 6.36 | No | Yes | 1 | 9 | 8 |
23 | R:R:L192 | R:R:S150 | 3 | No | No | 0 | 7 | 7 |
24 | R:R:G393 | R:R:S152 | 3.71 | No | No | 0 | 9 | 9 |
25 | R:R:L394 | R:R:S152 | 3 | No | No | 0 | 5 | 9 |
26 | R:R:G154 | R:R:L153 | 3.42 | No | No | 3 | 4 | 6 |
27 | R:R:L153 | R:R:L157 | 6.92 | No | No | 3 | 6 | 3 |
28 | R:R:G154 | R:R:L157 | 5.13 | No | No | 3 | 4 | 3 |
29 | R:R:F181 | R:R:L156 | 3.65 | Yes | Yes | 0 | 8 | 8 |
30 | R:R:L156 | R:R:V185 | 2.98 | Yes | No | 0 | 8 | 8 |
31 | R:R:G393 | R:R:L156 | 5.13 | No | Yes | 0 | 9 | 8 |
32 | R:R:A397 | R:R:L156 | 3.15 | No | Yes | 0 | 8 | 8 |
33 | R:R:L157 | R:R:V185 | 2.98 | No | No | 0 | 3 | 8 |
34 | R:R:F402 | R:R:L158 | 6.09 | No | No | 0 | 9 | 5 |
35 | R:R:A159 | R:R:C401 | 3.61 | No | Yes | 0 | 9 | 9 |
36 | R:R:F181 | R:R:L160 | 7.31 | Yes | No | 0 | 8 | 6 |
37 | R:R:C401 | R:R:I162 | 3.27 | Yes | No | 0 | 9 | 8 |
38 | R:R:K168 | R:R:L163 | 4.23 | Yes | No | 0 | 8 | 8 |
39 | R:R:C401 | R:R:L163 | 3.17 | Yes | No | 0 | 9 | 8 |
40 | R:R:K168 | R:R:L166 | 7.05 | Yes | No | 0 | 8 | 7 |
41 | R:R:L166 | R:R:R414 | 10.93 | No | No | 0 | 7 | 5 |
42 | R:R:E410 | R:R:S167 | 7.19 | Yes | No | 0 | 8 | 8 |
43 | R:R:C171 | R:R:K168 | 3.23 | No | Yes | 2 | 7 | 8 |
44 | R:R:K168 | R:R:N174 | 8.39 | Yes | No | 2 | 8 | 9 |
45 | R:R:H170 | R:R:L169 | 7.71 | No | No | 0 | 7 | 9 |
46 | R:R:C171 | R:R:N174 | 11.02 | No | No | 2 | 7 | 9 |
47 | R:R:S262 | R:R:T172 | 3.2 | No | No | 0 | 5 | 7 |
48 | R:R:N174 | R:R:R173 | 7.23 | No | Yes | 2 | 9 | 9 |
49 | R:R:H177 | R:R:R173 | 7.9 | No | Yes | 2 | 9 | 9 |
50 | R:R:N404 | R:R:R173 | 4.82 | Yes | Yes | 2 | 9 | 9 |
51 | R:R:E406 | R:R:R173 | 6.98 | Yes | Yes | 2 | 9 | 9 |
52 | R:R:I176 | R:R:V244 | 6.14 | No | No | 0 | 9 | 8 |
53 | R:R:E245 | R:R:I176 | 8.2 | Yes | No | 0 | 9 | 9 |
54 | R:R:I176 | R:R:L268 | 4.28 | No | No | 0 | 9 | 5 |
55 | R:R:E245 | R:R:H177 | 13.54 | Yes | No | 2 | 9 | 9 |
56 | R:R:H177 | R:R:Y400 | 16.33 | No | Yes | 2 | 9 | 8 |
57 | R:R:N179 | R:R:W241 | 16.95 | No | Yes | 4 | 8 | 9 |
58 | R:R:N179 | R:R:W272 | 5.65 | No | No | 4 | 8 | 9 |
59 | R:R:F184 | R:R:L180 | 3.65 | Yes | No | 0 | 8 | 9 |
60 | R:R:L180 | R:R:W241 | 3.42 | No | Yes | 0 | 9 | 9 |
61 | R:R:E245 | R:R:L180 | 3.98 | Yes | No | 0 | 9 | 9 |
62 | R:R:F181 | R:R:V396 | 3.93 | Yes | No | 0 | 8 | 9 |
63 | R:R:F181 | R:R:Y400 | 3.09 | Yes | Yes | 0 | 8 | 8 |
64 | R:R:F184 | R:R:S183 | 3.96 | Yes | No | 1 | 8 | 9 |
65 | R:R:N238 | R:R:S183 | 2.98 | Yes | No | 1 | 9 | 9 |
66 | R:R:F184 | R:R:N238 | 14.5 | Yes | Yes | 1 | 8 | 9 |
67 | R:R:F184 | R:R:Q392 | 5.86 | Yes | Yes | 1 | 8 | 9 |
68 | R:R:F184 | R:R:G393 | 4.52 | Yes | No | 0 | 8 | 9 |
69 | R:R:F184 | R:R:V396 | 3.93 | Yes | No | 0 | 8 | 9 |
70 | R:R:I235 | R:R:K187 | 5.82 | No | Yes | 0 | 5 | 8 |
71 | R:R:K187 | R:R:N238 | 4.2 | Yes | Yes | 1 | 8 | 9 |
72 | R:R:K187 | R:R:S389 | 4.59 | Yes | No | 1 | 8 | 6 |
73 | R:R:F230 | R:R:S190 | 5.28 | No | No | 0 | 4 | 5 |
74 | R:R:M231 | R:R:S190 | 4.6 | Yes | No | 0 | 6 | 5 |
75 | R:R:M231 | R:R:V191 | 4.56 | Yes | No | 0 | 6 | 7 |
76 | R:R:A227 | R:R:V193 | 3.39 | No | No | 0 | 6 | 5 |
77 | R:R:C224 | R:R:L197 | 4.76 | No | No | 0 | 9 | 4 |
78 | R:R:S217 | R:R:V221 | 3.23 | No | No | 0 | 4 | 4 |
79 | R:R:A222 | R:R:D218 | 3.09 | No | No | 0 | 4 | 4 |
80 | R:R:C224 | R:R:C294 | 5.46 | No | No | 5 | 9 | 9 |
81 | R:R:N291 | R:R:R225 | 9.64 | No | No | 0 | 6 | 8 |
82 | R:R:F303 | R:R:Q232 | 4.68 | Yes | No | 6 | 4 | 7 |
83 | R:R:L307 | R:R:Q232 | 5.32 | Yes | No | 6 | 7 | 7 |
84 | R:R:W272 | R:R:Y233 | 4.82 | No | Yes | 0 | 9 | 9 |
85 | R:R:M276 | R:R:Y233 | 5.99 | No | Yes | 0 | 3 | 9 |
86 | R:R:I235 | R:R:V236 | 3.07 | No | Yes | 0 | 5 | 6 |
87 | R:R:P275 | R:R:V236 | 5.3 | Yes | Yes | 0 | 9 | 6 |
88 | R:R:V236 | R:R:V279 | 6.41 | Yes | No | 7 | 6 | 6 |
89 | R:R:P310 | R:R:V236 | 5.3 | No | Yes | 7 | 9 | 6 |
90 | R:R:V236 | R:R:V311 | 4.81 | Yes | No | 0 | 6 | 8 |
91 | R:R:A237 | R:R:P275 | 3.74 | No | Yes | 0 | 7 | 9 |
92 | R:R:N238 | R:R:Y239 | 4.65 | Yes | Yes | 0 | 9 | 8 |
93 | R:R:L242 | R:R:Y239 | 3.52 | No | Yes | 0 | 9 | 8 |
94 | R:R:L358 | R:R:Y239 | 4.69 | No | Yes | 0 | 9 | 8 |
95 | R:R:G359 | R:R:Y239 | 4.35 | No | Yes | 0 | 9 | 8 |
96 | R:R:E362 | R:R:Y239 | 4.49 | Yes | Yes | 0 | 8 | 8 |
97 | R:R:C240 | R:R:W241 | 5.22 | No | Yes | 0 | 6 | 9 |
98 | R:R:C240 | R:R:P275 | 7.53 | No | Yes | 0 | 6 | 9 |
99 | R:R:V244 | R:R:W241 | 6.13 | No | Yes | 0 | 8 | 9 |
100 | R:R:W241 | R:R:W272 | 14.06 | Yes | No | 4 | 9 | 9 |
101 | R:R:I355 | R:R:L242 | 4.28 | Yes | No | 0 | 8 | 9 |
102 | R:R:L243 | R:R:L247 | 5.54 | No | No | 0 | 8 | 7 |
103 | R:R:I317 | R:R:L243 | 5.71 | No | No | 0 | 6 | 8 |
104 | R:R:L243 | R:R:N318 | 10.98 | No | No | 0 | 8 | 9 |
105 | R:R:V244 | R:R:Y248 | 7.57 | No | No | 0 | 8 | 8 |
106 | R:R:E245 | R:R:Y400 | 14.59 | Yes | Yes | 2 | 9 | 8 |
107 | R:R:F264 | R:R:Y248 | 17.54 | No | No | 0 | 6 | 8 |
108 | R:R:I325 | R:R:L249 | 4.28 | No | No | 0 | 9 | 9 |
109 | R:R:L249 | R:R:L347 | 4.15 | No | No | 0 | 9 | 9 |
110 | R:R:L249 | R:R:T351 | 5.9 | No | No | 0 | 9 | 9 |
111 | R:R:H250 | R:R:N251 | 6.38 | Yes | No | 0 | 7 | 7 |
112 | R:R:H250 | R:R:R324 | 6.77 | Yes | No | 0 | 7 | 8 |
113 | R:R:H250 | R:R:I325 | 3.98 | Yes | No | 0 | 7 | 9 |
114 | R:R:L252 | R:R:L253 | 4.15 | No | No | 0 | 8 | 8 |
115 | R:R:L252 | R:R:R261 | 3.64 | No | No | 0 | 8 | 5 |
116 | R:R:L253 | R:R:Y343 | 7.03 | No | No | 0 | 8 | 7 |
117 | R:R:K344 | R:R:L253 | 7.05 | No | No | 0 | 6 | 8 |
118 | R:R:G254 | R:R:L328 | 3.42 | No | No | 0 | 6 | 8 |
119 | R:R:L255 | R:R:L258 | 5.54 | No | No | 0 | 5 | 6 |
120 | R:R:L258 | R:R:P259 | 3.28 | No | No | 0 | 6 | 6 |
121 | R:R:E260 | R:R:P259 | 9.43 | No | No | 0 | 6 | 6 |
122 | R:R:L266 | R:R:Y267 | 5.86 | No | No | 0 | 3 | 7 |
123 | R:R:M276 | R:R:V280 | 9.13 | No | No | 0 | 3 | 2 |
124 | R:R:F278 | R:R:L277 | 6.09 | No | No | 0 | 5 | 4 |
125 | R:R:F278 | R:R:F309 | 11.79 | No | No | 0 | 5 | 4 |
126 | R:R:P310 | R:R:V279 | 3.53 | No | No | 7 | 9 | 6 |
127 | R:R:P281 | R:R:V280 | 3.53 | No | No | 0 | 4 | 2 |
128 | R:R:V280 | R:R:V284 | 3.21 | No | No | 0 | 2 | 4 |
129 | R:R:P281 | R:R:W282 | 4.05 | No | No | 0 | 4 | 9 |
130 | R:R:W282 | R:R:W305 | 11.25 | No | No | 0 | 9 | 7 |
131 | R:R:A283 | R:R:I306 | 6.5 | No | No | 0 | 5 | 8 |
132 | R:R:G302 | R:R:K286 | 3.49 | No | No | 0 | 2 | 8 |
133 | R:R:E290 | R:R:F289 | 13.99 | No | No | 0 | 6 | 3 |
134 | R:R:Q293 | R:R:V292 | 10.03 | No | No | 0 | 4 | 4 |
135 | R:R:Q293 | R:R:S297 | 7.22 | No | No | 0 | 4 | 4 |
136 | R:R:F303 | R:R:T296 | 5.19 | Yes | No | 0 | 4 | 5 |
137 | R:R:F303 | R:R:I306 | 10.05 | Yes | No | 0 | 4 | 8 |
138 | R:R:F303 | R:R:L307 | 4.87 | Yes | Yes | 6 | 4 | 7 |
139 | R:R:R308 | R:R:W304 | 11 | No | No | 0 | 6 | 6 |
140 | R:R:L307 | R:R:R308 | 3.64 | Yes | No | 0 | 7 | 6 |
141 | R:R:A366 | R:R:R308 | 5.53 | No | No | 0 | 7 | 6 |
142 | R:R:F309 | R:R:P310 | 10.11 | No | No | 0 | 4 | 9 |
143 | R:R:G359 | R:R:I315 | 3.53 | No | No | 0 | 9 | 7 |
144 | R:R:I315 | R:R:V363 | 6.14 | No | No | 0 | 7 | 6 |
145 | R:R:F320 | R:R:L316 | 3.65 | No | No | 0 | 5 | 3 |
146 | R:R:I355 | R:R:N318 | 11.33 | Yes | No | 0 | 8 | 9 |
147 | R:R:F319 | R:R:F320 | 9.65 | No | No | 0 | 7 | 5 |
148 | R:R:F319 | R:R:V323 | 3.93 | No | No | 0 | 7 | 5 |
149 | R:R:F322 | R:R:I355 | 5.02 | No | Yes | 0 | 9 | 8 |
150 | R:R:K332 | R:R:Q337 | 12.2 | No | No | 0 | 9 | 7 |
151 | R:R:K332 | R:R:M338 | 8.64 | No | Yes | 0 | 9 | 5 |
152 | R:R:H339 | R:R:R336 | 7.9 | No | No | 8 | 4 | 5 |
153 | R:R:H340 | R:R:R336 | 3.39 | No | No | 8 | 5 | 5 |
154 | R:R:K344 | R:R:M338 | 23.04 | No | Yes | 0 | 6 | 5 |
155 | R:R:H339 | R:R:H340 | 7.17 | No | No | 8 | 4 | 5 |
156 | R:R:H339 | R:R:T341 | 9.58 | No | No | 0 | 4 | 6 |
157 | R:R:D342 | R:R:Y343 | 4.6 | No | No | 0 | 7 | 7 |
158 | R:R:D342 | R:R:K344 | 12.44 | No | No | 0 | 7 | 6 |
159 | R:R:R346 | R:R:Y343 | 3.09 | Yes | No | 0 | 8 | 7 |
160 | R:R:N404 | R:R:R346 | 7.23 | Yes | Yes | 2 | 9 | 8 |
161 | R:R:K405 | R:R:R346 | 8.66 | No | Yes | 0 | 6 | 8 |
162 | R:R:E406 | R:R:R346 | 4.65 | Yes | Yes | 2 | 9 | 8 |
163 | R:R:L399 | R:R:S350 | 4.5 | No | No | 0 | 8 | 9 |
164 | R:R:S350 | R:R:Y400 | 6.36 | No | Yes | 0 | 9 | 8 |
165 | R:R:T351 | R:R:Y400 | 7.49 | No | Yes | 0 | 9 | 8 |
166 | R:R:L354 | R:R:V396 | 7.45 | No | No | 0 | 9 | 9 |
167 | R:R:L354 | R:R:Y400 | 4.69 | No | Yes | 0 | 9 | 8 |
168 | R:R:I355 | R:R:P356 | 5.08 | Yes | No | 0 | 8 | 9 |
169 | R:R:L358 | R:R:Q392 | 9.32 | No | Yes | 0 | 9 | 9 |
170 | R:R:E362 | R:R:H361 | 9.85 | Yes | No | 1 | 8 | 8 |
171 | R:R:H361 | R:R:L388 | 7.71 | No | No | 0 | 8 | 6 |
172 | R:R:H361 | R:R:Q392 | 11.13 | No | Yes | 1 | 8 | 9 |
173 | R:R:E362 | R:R:F365 | 9.33 | Yes | No | 0 | 8 | 7 |
174 | R:R:E362 | R:R:S389 | 7.19 | Yes | No | 1 | 8 | 6 |
175 | R:R:E362 | R:R:Q392 | 6.37 | Yes | Yes | 1 | 8 | 9 |
176 | R:R:V364 | R:R:V368 | 12.83 | No | No | 0 | 6 | 5 |
177 | R:R:D385 | R:R:F365 | 15.52 | No | No | 0 | 7 | 7 |
178 | R:R:L377 | R:R:Q374 | 9.32 | No | No | 0 | 3 | 4 |
179 | R:R:L382 | R:R:L386 | 4.15 | No | No | 0 | 5 | 7 |
180 | R:R:F384 | R:R:L388 | 4.87 | No | No | 0 | 4 | 6 |
181 | R:R:F391 | R:R:S390 | 6.61 | No | No | 1 | 7 | 9 |
182 | R:R:L394 | R:R:V398 | 2.98 | No | No | 0 | 5 | 6 |
183 | R:R:L395 | R:R:L399 | 8.3 | No | No | 0 | 6 | 8 |
184 | R:R:L403 | R:R:V398 | 2.98 | No | No | 0 | 5 | 6 |
185 | R:R:C401 | R:R:F402 | 4.19 | Yes | No | 0 | 9 | 9 |
186 | R:R:E406 | R:R:N404 | 6.57 | Yes | Yes | 2 | 9 | 9 |
187 | R:R:N404 | R:R:V407 | 7.39 | Yes | No | 0 | 9 | 9 |
188 | R:R:E410 | R:R:R413 | 11.63 | Yes | No | 0 | 8 | 7 |
189 | R:R:E410 | R:R:R414 | 4.65 | Yes | No | 0 | 8 | 5 |
190 | R:R:R413 | R:R:R417 | 5.33 | No | No | 0 | 7 | 7 |
191 | R:R:H416 | R:R:W415 | 8.46 | No | No | 0 | 3 | 5 |
192 | R:R:R419 | R:R:W415 | 14.99 | No | No | 0 | 5 | 5 |
193 | R:R:K422 | R:R:W418 | 9.28 | No | No | 0 | 5 | 3 |
194 | R:R:L420 | R:R:L424 | 6.92 | No | No | 0 | 4 | 4 |
195 | R:R:E426 | R:R:W425 | 4.36 | No | No | 0 | 4 | 2 |
196 | R:R:R428 | R:R:W425 | 7 | No | No | 9 | 2 | 2 |
197 | R:R:N429 | R:R:W425 | 9.04 | No | No | 9 | 5 | 2 |
198 | R:R:N429 | R:R:R428 | 6.03 | No | No | 9 | 5 | 2 |
199 | R:R:L258 | R:R:T257 | 2.95 | No | No | 0 | 6 | 7 |
200 | R:R:L377 | R:R:T376 | 2.95 | No | No | 0 | 3 | 2 |
201 | R:R:I194 | R:R:M231 | 2.92 | Yes | Yes | 0 | 6 | 6 |
202 | R:R:G234 | R:R:Y233 | 2.9 | No | Yes | 0 | 5 | 9 |
203 | R:R:D299 | R:R:T296 | 2.89 | No | No | 0 | 4 | 5 |
204 | R:R:I162 | R:R:L411 | 2.85 | No | No | 0 | 8 | 5 |
205 | R:R:I194 | R:R:L198 | 2.85 | Yes | No | 0 | 6 | 6 |
206 | R:R:I235 | R:R:L307 | 2.85 | No | Yes | 0 | 5 | 7 |
207 | R:R:I321 | R:R:L247 | 2.85 | No | No | 0 | 8 | 7 |
208 | R:R:L329 | R:R:M338 | 2.83 | No | Yes | 0 | 9 | 5 |
209 | R:R:G269 | R:R:W241 | 2.81 | No | Yes | 0 | 4 | 9 |
210 | R:R:D385 | R:R:K381 | 2.77 | No | No | 0 | 7 | 7 |
211 | R:R:E129 | R:R:K132 | 2.7 | No | No | 0 | 1 | 2 |
212 | R:R:A314 | R:R:Y239 | 2.67 | No | Yes | 0 | 8 | 8 |
213 | R:R:F383 | R:R:S379 | 2.64 | No | No | 0 | 5 | 3 |
214 | R:R:D195 | R:R:Q142 | 2.61 | Yes | No | 0 | 7 | 5 |
215 | R:R:V134 | R:R:Y138 | 2.52 | No | No | 0 | 2 | 5 |
216 | R:R:F345 | R:R:M338 | 2.49 | No | Yes | 0 | 7 | 5 |
217 | R:R:F322 | R:R:L352 | 2.44 | No | No | 0 | 9 | 8 |
218 | R:R:L186 | R:R:Y233 | 2.34 | No | Yes | 0 | 7 | 9 |
219 | R:R:M231 | R:R:W295 | 2.33 | Yes | No | 0 | 6 | 9 |
220 | R:R:E260 | R:R:F264 | 2.33 | No | No | 0 | 6 | 6 |
221 | R:R:M301 | R:R:W305 | 2.33 | No | No | 0 | 5 | 7 |
222 | R:R:H416 | R:R:R412 | 2.26 | No | No | 0 | 3 | 5 |
223 | R:R:F387 | R:R:F391 | 2.14 | No | No | 0 | 5 | 7 |
224 | R:R:G164 | R:R:G165 | 2.11 | No | No | 0 | 3 | 3 |
225 | R:R:G273 | R:R:P275 | 2.03 | No | Yes | 0 | 6 | 9 |
226 | R:R:F367 | R:R:W304 | 2 | No | No | 0 | 5 | 6 |
227 | R:R:A274 | R:R:P275 | 1.87 | No | Yes | 0 | 4 | 9 |
228 | R:R:G223 | R:R:V226 | 1.84 | No | No | 0 | 3 | 4 |
229 | R:R:A155 | R:R:A397 | 1.79 | No | No | 0 | 6 | 8 |
230 | R:R:G125 | R:R:I128 | 1.76 | No | No | 0 | 2 | 2 |
231 | R:R:G246 | R:R:I321 | 1.76 | No | No | 0 | 9 | 8 |
232 | R:R:G302 | R:R:I306 | 1.76 | No | No | 0 | 2 | 8 |
233 | R:R:G165 | R:R:L166 | 1.71 | No | No | 0 | 3 | 7 |
234 | R:R:G165 | R:R:L169 | 1.71 | No | No | 0 | 3 | 9 |
235 | R:R:D124 | R:R:G125 | 1.68 | No | No | 0 | 2 | 2 |
236 | R:R:D195 | R:R:G196 | 1.68 | Yes | No | 0 | 7 | 3 |
237 | R:R:C224 | R:R:I194 | 1.64 | No | Yes | 5 | 9 | 6 |
238 | R:R:C294 | R:R:I194 | 1.64 | No | Yes | 5 | 9 | 6 |
239 | R:R:G375 | R:R:Q374 | 1.64 | No | No | 0 | 2 | 4 |
240 | R:R:S139 | R:R:S140 | 1.63 | No | No | 0 | 3 | 4 |
241 | R:R:S189 | R:R:S190 | 1.63 | No | No | 0 | 4 | 5 |
242 | R:R:A227 | R:R:I194 | 1.62 | No | Yes | 0 | 6 | 6 |
243 | R:R:A228 | R:R:I194 | 1.62 | No | Yes | 0 | 5 | 6 |
244 | R:R:A331 | R:R:K332 | 1.61 | No | No | 0 | 7 | 9 |
245 | R:R:A348 | R:R:M338 | 1.61 | No | Yes | 0 | 7 | 5 |
246 | R:R:V130 | R:R:V134 | 1.6 | No | No | 0 | 1 | 2 |
247 | R:R:S150 | R:R:T146 | 1.6 | No | No | 0 | 7 | 7 |
248 | R:R:V229 | R:R:V284 | 1.6 | No | No | 0 | 6 | 4 |
249 | R:R:V284 | R:R:V285 | 1.6 | No | No | 0 | 4 | 5 |
250 | R:R:V360 | R:R:V364 | 1.6 | No | No | 0 | 6 | 6 |
251 | R:R:T369 | R:R:V368 | 1.59 | No | No | 0 | 7 | 5 |
252 | R:R:A178 | R:R:L160 | 1.58 | No | No | 0 | 7 | 6 |
253 | R:R:A220 | R:R:L197 | 1.58 | No | No | 0 | 6 | 4 |
254 | R:R:K136 | R:R:S139 | 1.53 | No | No | 0 | 2 | 3 |
255 | R:R:A373 | R:R:Q374 | 1.52 | No | No | 0 | 3 | 4 |
256 | R:R:A373 | R:R:E371 | 1.51 | No | No | 0 | 3 | 5 |
257 | R:R:K405 | R:R:T341 | 1.5 | No | No | 0 | 6 | 6 |
258 | R:R:K381 | R:R:T369 | 1.5 | No | No | 0 | 7 | 7 |
259 | R:R:G375 | R:R:R378 | 1.5 | No | No | 0 | 2 | 4 |
260 | R:R:L352 | R:R:V326 | 1.49 | No | No | 0 | 8 | 7 |
261 | R:R:L197 | R:R:T200 | 1.47 | No | No | 0 | 4 | 3 |
262 | R:R:D299 | R:R:S297 | 1.47 | No | No | 0 | 4 | 4 |
263 | R:R:L352 | R:R:T353 | 1.47 | No | No | 0 | 8 | 8 |
264 | R:R:L399 | R:R:T353 | 1.47 | No | No | 0 | 8 | 8 |
265 | R:R:D218 | R:R:V221 | 1.46 | No | No | 0 | 4 | 4 |
266 | R:R:N291 | R:R:T296 | 1.46 | No | No | 0 | 6 | 5 |
267 | R:R:Q142 | R:R:S139 | 1.44 | No | No | 0 | 5 | 3 |
268 | R:R:E406 | R:R:S409 | 1.44 | Yes | No | 0 | 9 | 4 |
269 | R:R:E410 | R:R:S409 | 1.44 | Yes | No | 0 | 8 | 4 |
270 | R:R:A222 | R:R:R225 | 1.38 | No | No | 0 | 4 | 8 |
271 | R:R:L357 | R:R:L395 | 1.38 | No | No | 0 | 9 | 6 |
272 | R:R:E129 | R:R:I128 | 1.37 | No | No | 0 | 1 | 2 |
273 | R:R:N298 | R:R:N300 | 1.36 | No | No | 0 | 6 | 5 |
274 | R:R:E427 | R:R:L424 | 1.33 | No | No | 0 | 5 | 4 |
275 | R:R:F322 | R:R:V323 | 1.31 | No | No | 0 | 9 | 5 |
276 | R:R:H250 | R:R:L328 | 1.29 | Yes | No | 0 | 7 | 8 |
277 | R:R:F345 | R:R:K349 | 1.24 | No | No | 0 | 7 | 9 |
278 | R:R:E371 | R:R:H372 | 1.23 | No | No | 0 | 5 | 4 |
279 | R:R:D370 | R:R:F367 | 1.19 | No | No | 0 | 4 | 5 |
280 | R:R:L382 | R:R:W295 | 1.14 | No | No | 0 | 5 | 9 |
281 | R:R:N300 | R:R:W304 | 1.13 | No | No | 0 | 5 | 6 |
282 | R:R:F312 | R:R:F367 | 1.07 | No | No | 0 | 5 | 5 |
283 | R:R:Y248 | R:R:Y267 | 0.99 | No | No | 0 | 8 | 7 |
Color | ConSurf Grade |
No Conservation data available | |
1 | |
2 | |
3 | |
4 | |
5 | |
6 | |
7 | |
8 | |
9 |
Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.
Hub: the hub being considered.
Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.
Num Of Links: the number of links of the corresponding hub.
Community: the id of the community the link belong to, otherwise 0.
ConSurf: this column reports the ConSurf conservation grades of each hub.
Index | Hub | Avg Int. Strength | Num Of Links | Community | ConSurf |
---|---|---|---|---|---|
1 | R:R:Y149 | 6.12333 | 6 | 1 | 8 |
2 | R:R:L156 | 3.7275 | 4 | 0 | 8 |
3 | R:R:K168 | 5.725 | 4 | 2 | 8 |
4 | R:R:R173 | 6.7325 | 4 | 2 | 9 |
5 | R:R:F181 | 4.495 | 4 | 0 | 8 |
6 | R:R:F184 | 6.07 | 6 | 1 | 8 |
7 | R:R:K187 | 5.145 | 4 | 1 | 8 |
8 | R:R:I194 | 2.04833 | 6 | 5 | 6 |
9 | R:R:D195 | 4.3175 | 4 | 1 | 7 |
10 | R:R:M231 | 3.6025 | 4 | 0 | 6 |
11 | R:R:Y233 | 4.0125 | 4 | 0 | 9 |
12 | R:R:V236 | 4.978 | 5 | 7 | 6 |
13 | R:R:N238 | 6.5825 | 4 | 1 | 9 |
14 | R:R:Y239 | 4.06167 | 6 | 0 | 8 |
15 | R:R:W241 | 8.09833 | 6 | 4 | 9 |
16 | R:R:E245 | 10.0775 | 4 | 2 | 9 |
17 | R:R:H250 | 4.605 | 4 | 0 | 7 |
18 | R:R:P275 | 4.094 | 5 | 0 | 9 |
19 | R:R:F303 | 6.1975 | 4 | 6 | 4 |
20 | R:R:L307 | 4.17 | 4 | 6 | 7 |
21 | R:R:M338 | 7.722 | 5 | 0 | 5 |
22 | R:R:R346 | 5.9075 | 4 | 2 | 8 |
23 | R:R:I355 | 6.4275 | 4 | 0 | 8 |
24 | R:R:E362 | 7.446 | 5 | 1 | 8 |
25 | R:R:Q392 | 8.17 | 4 | 1 | 9 |
26 | R:R:Y400 | 8.75833 | 6 | 2 | 8 |
27 | R:R:C401 | 3.56 | 4 | 0 | 9 |
28 | R:R:N404 | 6.5025 | 4 | 2 | 9 |
29 | R:R:E406 | 4.91 | 4 | 2 | 9 |
30 | R:R:E410 | 6.2275 | 4 | 0 | 8 |
Color | ConSurf Grade |
No Conservation data available | |
1 | |
2 | |
3 | |
4 | |
5 | |
6 | |
7 | |
8 | |
9 |
Index: link id, click on each number to highlight the corresponding link in the 3D visualization.
Node1 Node2: the two nodes of the corresponding link.
Recurrence: the relative Recurrence in the pool of shortest paths.
Int. Strength: the interaction strength between the two nodes.
Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".
Community: the id of the community the link belong to, otherwise 0.
ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.
Index | Node1 | Node2 | Recurrence | Int. Strength | Hub1? | Hub2? | Community | ConSurf1 | ConSurf2 |
---|---|---|---|---|---|---|---|---|---|
1 | R:R:D124 | R:R:G125 | 11.1137 | 1.68 | No | No | 0 | 2 | 2 |
2 | R:R:D124 | R:R:E127 | 12.9266 | 3.9 | No | No | 0 | 2 | 1 |
3 | R:R:E127 | R:R:V130 | 14.7281 | 4.28 | No | No | 0 | 1 | 1 |
4 | R:R:D195 | R:R:Y145 | 12.8058 | 5.75 | Yes | No | 1 | 7 | 7 |
5 | R:R:Y145 | R:R:Y149 | 20.0633 | 3.97 | No | Yes | 1 | 7 | 8 |
6 | R:R:S390 | R:R:Y149 | 35.4187 | 6.36 | No | Yes | 1 | 9 | 8 |
7 | R:R:F391 | R:R:S390 | 31.977 | 6.61 | No | No | 1 | 7 | 9 |
8 | R:R:F387 | R:R:F391 | 30.3942 | 2.14 | No | No | 0 | 5 | 7 |
9 | R:R:F387 | R:R:M144 | 28.6964 | 4.98 | No | No | 0 | 5 | 6 |
10 | R:R:F141 | R:R:M144 | 26.987 | 6.22 | No | No | 0 | 6 | 6 |
11 | R:R:F141 | R:R:F383 | 23.5338 | 7.5 | No | No | 0 | 6 | 5 |
12 | R:R:F383 | R:R:Y138 | 20.0288 | 8.25 | No | No | 0 | 5 | 5 |
13 | R:R:V134 | R:R:Y138 | 18.2619 | 2.52 | No | No | 0 | 2 | 5 |
14 | R:R:V130 | R:R:V134 | 16.518 | 1.6 | No | No | 0 | 1 | 2 |
15 | R:R:K187 | R:R:Y149 | 70.3885 | 5.97 | Yes | Yes | 1 | 8 | 8 |
16 | R:R:V191 | R:R:Y149 | 32.0748 | 12.62 | No | Yes | 0 | 7 | 8 |
17 | R:R:S389 | R:R:Y149 | 10.8432 | 3.82 | No | Yes | 1 | 6 | 8 |
18 | R:R:F184 | R:R:G393 | 13.3468 | 4.52 | Yes | No | 0 | 8 | 9 |
19 | R:R:F184 | R:R:N238 | 91.6432 | 14.5 | Yes | Yes | 1 | 8 | 9 |
20 | R:R:K187 | R:R:N238 | 90.3424 | 4.2 | Yes | Yes | 1 | 8 | 9 |
21 | R:R:F181 | R:R:V396 | 11.3381 | 3.93 | Yes | No | 0 | 8 | 9 |
22 | R:R:F184 | R:R:V396 | 20.5986 | 3.93 | Yes | No | 0 | 8 | 9 |
23 | R:R:K168 | R:R:L163 | 11.436 | 4.23 | Yes | No | 0 | 8 | 8 |
24 | R:R:K168 | R:R:N174 | 21.4504 | 8.39 | Yes | No | 2 | 8 | 9 |
25 | R:R:N174 | R:R:R173 | 24.4777 | 7.23 | No | Yes | 2 | 9 | 9 |
26 | R:R:H177 | R:R:R173 | 100 | 7.9 | No | Yes | 2 | 9 | 9 |
27 | R:R:E245 | R:R:H177 | 77.2201 | 13.54 | Yes | No | 2 | 9 | 9 |
28 | R:R:E245 | R:R:L180 | 84.5295 | 3.98 | Yes | No | 0 | 9 | 9 |
29 | R:R:F184 | R:R:L180 | 84.1496 | 3.65 | Yes | No | 0 | 8 | 9 |
30 | R:R:E406 | R:R:R173 | 45.7094 | 6.98 | Yes | Yes | 2 | 9 | 9 |
31 | R:R:N404 | R:R:R173 | 39.7813 | 4.82 | Yes | Yes | 2 | 9 | 9 |
32 | R:R:L180 | R:R:W241 | 33.6978 | 3.42 | No | Yes | 0 | 9 | 9 |
33 | R:R:E245 | R:R:Y400 | 13.9683 | 14.59 | Yes | Yes | 2 | 9 | 8 |
34 | R:R:F181 | R:R:Y400 | 19.0849 | 3.09 | Yes | Yes | 0 | 8 | 8 |
35 | R:R:W241 | R:R:W272 | 19.9712 | 14.06 | Yes | No | 4 | 9 | 9 |
36 | R:R:E362 | R:R:S389 | 14.4518 | 7.19 | Yes | No | 1 | 8 | 6 |
37 | R:R:E362 | R:R:Q392 | 10.1698 | 6.37 | Yes | Yes | 1 | 8 | 9 |
38 | R:R:I235 | R:R:K187 | 44.0115 | 5.82 | No | Yes | 0 | 5 | 8 |
39 | R:R:M231 | R:R:V191 | 30.3885 | 4.56 | Yes | No | 0 | 6 | 7 |
40 | R:R:I194 | R:R:M231 | 18.2964 | 2.92 | Yes | Yes | 0 | 6 | 6 |
41 | R:R:I235 | R:R:L307 | 42.0432 | 2.85 | No | Yes | 0 | 5 | 7 |
42 | R:R:F303 | R:R:L307 | 26.6993 | 4.87 | Yes | Yes | 6 | 4 | 7 |
43 | R:R:F303 | R:R:T296 | 18.7338 | 5.19 | Yes | No | 0 | 4 | 5 |
44 | R:R:N291 | R:R:T296 | 10.3885 | 1.46 | No | No | 0 | 6 | 5 |
45 | R:R:W272 | R:R:Y233 | 18.5727 | 4.82 | No | Yes | 0 | 9 | 9 |
46 | R:R:M276 | R:R:Y233 | 14.0835 | 5.99 | No | Yes | 0 | 3 | 9 |
47 | R:R:I235 | R:R:V236 | 12.9324 | 3.07 | No | Yes | 0 | 5 | 6 |
48 | R:R:P275 | R:R:V236 | 12.8921 | 5.3 | Yes | Yes | 0 | 9 | 6 |
49 | R:R:N238 | R:R:Y239 | 25.4504 | 4.65 | Yes | Yes | 0 | 9 | 8 |
50 | R:R:L242 | R:R:Y239 | 24.5698 | 3.52 | No | Yes | 0 | 9 | 8 |
51 | R:R:C240 | R:R:P275 | 13.7899 | 7.53 | No | Yes | 0 | 6 | 9 |
52 | R:R:I355 | R:R:L242 | 22.8029 | 4.28 | Yes | No | 0 | 8 | 9 |
53 | R:R:I355 | R:R:N318 | 14.0489 | 11.33 | Yes | No | 0 | 8 | 9 |
54 | R:R:L243 | R:R:N318 | 11.7353 | 10.98 | No | No | 0 | 8 | 9 |
55 | R:R:V244 | R:R:Y248 | 14.4978 | 7.57 | No | No | 0 | 8 | 8 |
56 | R:R:T351 | R:R:Y400 | 24.5986 | 7.49 | No | Yes | 0 | 9 | 8 |
57 | R:R:L249 | R:R:T351 | 21.9108 | 5.9 | No | No | 0 | 9 | 9 |
58 | R:R:I325 | R:R:L249 | 16.5007 | 4.28 | No | No | 0 | 9 | 9 |
59 | R:R:H250 | R:R:I325 | 13.7784 | 3.98 | Yes | No | 0 | 7 | 9 |
60 | R:R:N404 | R:R:R346 | 37.5482 | 7.23 | Yes | Yes | 2 | 9 | 8 |
61 | R:R:R346 | R:R:Y343 | 61.6806 | 3.09 | Yes | No | 0 | 8 | 7 |
62 | R:R:L253 | R:R:Y343 | 32.2647 | 7.03 | No | No | 0 | 8 | 7 |
63 | R:R:E406 | R:R:R346 | 39.1885 | 4.65 | Yes | Yes | 2 | 9 | 8 |
64 | R:R:K344 | R:R:L253 | 24.3568 | 7.05 | No | No | 0 | 6 | 8 |
65 | R:R:D342 | R:R:Y343 | 26.8892 | 4.6 | No | No | 0 | 7 | 7 |
66 | R:R:D342 | R:R:K344 | 24.2532 | 12.44 | No | No | 0 | 7 | 6 |
67 | R:R:M276 | R:R:V280 | 12.564 | 9.13 | No | No | 0 | 3 | 2 |
68 | R:R:L307 | R:R:R308 | 13.7612 | 3.64 | Yes | No | 0 | 7 | 6 |
69 | R:R:R308 | R:R:W304 | 10.3885 | 11 | No | No | 0 | 6 | 6 |
70 | R:R:F322 | R:R:I355 | 14.0086 | 5.02 | No | Yes | 0 | 9 | 8 |
71 | R:R:K344 | R:R:M338 | 43.2288 | 23.04 | No | Yes | 0 | 6 | 5 |
72 | R:R:K332 | R:R:M338 | 16.2935 | 8.64 | No | Yes | 0 | 9 | 5 |
73 | R:R:K405 | R:R:T341 | 11.1597 | 1.5 | No | No | 0 | 6 | 6 |
74 | R:R:K405 | R:R:R346 | 13.9223 | 8.66 | No | Yes | 0 | 6 | 8 |
75 | R:R:S350 | R:R:Y400 | 20.7942 | 6.36 | No | Yes | 0 | 9 | 8 |
76 | R:R:L399 | R:R:S350 | 18.2561 | 4.5 | No | No | 0 | 8 | 9 |
77 | R:R:E362 | R:R:F365 | 12.1612 | 9.33 | Yes | No | 0 | 8 | 7 |
78 | R:R:D385 | R:R:F365 | 10.4576 | 15.52 | No | No | 0 | 7 | 7 |
79 | R:R:F345 | R:R:M338 | 10.8719 | 2.49 | No | Yes | 0 | 7 | 5 |
80 | R:R:F322 | R:R:L352 | 11.4763 | 2.44 | No | No | 0 | 9 | 8 |
81 | R:R:L352 | R:R:T353 | 11.1309 | 1.47 | No | No | 0 | 8 | 8 |
82 | R:R:F184 | R:R:Q392 | 14.5784 | 5.86 | Yes | Yes | 1 | 8 | 9 |
83 | R:R:L399 | R:R:T353 | 11.0906 | 1.47 | No | No | 0 | 8 | 8 |
84 | R:R:H177 | R:R:Y400 | 23.4763 | 16.33 | No | Yes | 2 | 9 | 8 |
85 | R:R:C240 | R:R:W241 | 14.3482 | 5.22 | No | Yes | 0 | 6 | 9 |
2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):
A 2D representation of the global communication in the network.
ConSurf Conservation Grade (See documentation):
n/a 1 2 3 4 5 6 7 8 9
there is no ligand in network 4L6R |
|
|
|
Annotation | Type | Links |
---|---|---|
Gene Ontology | Molecular Function | |
Gene Ontology | Biological Process | |
Gene Ontology | Cellular Component | |
SCOP2 | Domain Identifier | |
SCOP2 | Family Identifier | |
Membrane Protein Annotations | - | • Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD |
PDBsum | Open PDBsum Page |
Chain | R |
Protein | Receptor |
UniProt | P47871 |
Sequence | >4L6R_Chain_R MDGEEIEVQ KEVAKMYSS FQVMYTVGY SLSLGALLL ALAILGGLS KLHCTRNAI HANLFASFV LKASSVLVI DGLLRTLSD GAVAGCRVA AVFMQYGIV ANYCWLLVE GLYLHNLLG LATLPERSF FSLYLGIGW GAPMLFVVP WAVVKCLFE NVQCWTSND NMGFWWILR FPVFLAILI NFFIFVRIV QLLVAKLRA RQMHHTDYK FRLAKSTLT LIPLLGVHE VVFAFVTDE HAQGTLRSA KLFFDLFLS SFQGLLVAV LYCFLNKEV QSELRRRWH RWRLGKVLW EERN Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9 |
This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks: | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
7CZ5 | B1 | Peptide | Glucagon | GHRH | Homo sapiens | Somatoliberin | - | Gs/&β;1/&γ;2 | 2.6 | 2020-11-18 | 10.1038/s41467-020-18945-0 | |
7V9L | B1 | Peptide | Glucagon | GHRH (SV1) | Homo sapiens | - | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 2.6 | 2022-04-06 | 10.1073/pnas.2106606118 | |
7V9M | B1 | Peptide | Glucagon | GHRH (SV1) | Homo sapiens | Somatoliberin | - | Gs/&β;1/&γ;2 | 3.29 | 2021-10-20 | 10.1073/pnas.2106606118 | |
7DTY | B1 | Peptide | Glucagon | GIP | Homo sapiens | GIP | - | Gs/&β;1/&γ;2 | 2.98 | 2021-08-04 | 10.7554/eLife.68719 | |
7FIN | B1 | Peptide | Glucagon | GIP | Homo sapiens | Peptide-20; GGL | - | Gs/&β;1/&γ;2 | 3.1 | 2022-02-23 | 10.1038/s41467-022-28683-0 | |
7FIY | B1 | Peptide | Glucagon | GIP | Homo sapiens | Tirzepatide | - | Gs/&β;1/&γ;2 | 3.4 | 2022-03-02 | 10.1038/s41467-022-28683-0 | |
7RA3 | B1 | Peptide | Glucagon | GIP | Homo sapiens | GIP | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 3.24 | 2022-04-13 | 10.1073/pnas.2116506119 | |
7RBT | B1 | Peptide | Glucagon | GIP | Homo sapiens | Tirzepatide | PubChem 163183774 | chim(NtGi1-Gs)/&β;1/&γ;2 | 3.08 | 2022-04-13 | 10.1073/pnas.2116506119 | |
7VAB | B1 | Peptide | Glucagon | GIP | Homo sapiens | Non-Acylated Tirzepatide | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 3.2 | 2022-03-02 | 10.1038/s41467-022-28683-0 | |
8ITL | B1 | Peptide | Glucagon | GIP | Homo sapiens | - | - | Gs/&β;1/&γ;2 | 3.23 | 2023-10-18 | 10.1073/pnas.2306145120 | |
8ITM | B1 | Peptide | Glucagon | GIP | Homo sapiens | - | - | Gs/&β;1/&γ;2 | 3.13 | 2023-10-18 | 10.1073/pnas.2306145120 | |
8WA3 | B1 | Peptide | Glucagon | GIP | Homo sapiens | - | - | Gs/&β;1/&γ;2 | 2.86 | 2024-03-06 | 10.1038/s41421-024-00649-0 | |
5NX2 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | GLP-1 (Truncated) | - | - | 3.7 | 2017-06-14 | 10.1038/nature22800 | |
5VAI | B1 | Peptide | Glucagon | GLP-1 | Oryctolagus cuniculus | GLP-1 | - | Gs/&β;1/&γ;2 | 4.1 | 2017-05-24 | 10.1038/nature22394 | |
5VEW | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PF-06372222 | - | 2.7 | 2017-05-24 | 10.1038/nature22378 | |
5VEX | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | NNC0640 | - | 3 | 2017-05-17 | 10.1038/nature22378 | |
6B3J | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Exendin-P5 | - | Gs/&β;1/&γ;2 | 3.3 | 2018-02-21 | 10.1038/nature25773 | |
6KJV | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PubChem 68178630 | - | 2.8 | 2019-11-13 | 10.1107/S2052252519013496 | |
6KK1 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PubChem 68178630 | - | 2.8 | 2019-11-13 | 10.1107/S2052252519013496 | |
6KK7 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PubChem 68178630 | - | 3.1 | 2019-11-13 | 10.1107/S2052252519013496 | |
6LN2 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PubChem 68178630 | - | 3.2 | 2020-03-18 | 10.1038/s41467-020-14934-5 | |
6ORV | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | TT-OAD2 | Gs/&β;1/&γ;2 | 3 | 2020-01-08 | 10.1038/s41586-019-1902-z | |
6VCB | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | GLP-1 | LSN3160440 | Gs/&β;1/&γ;2 | 3.3 | 2020-07-22 | 10.1038/s41589-020-0589-7 | |
6X18 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | GLP-1 | - | Gs/&β;1/&γ;2 | 2.1 | 2020-09-09 | 10.1016/j.molcel.2020.09.020 | |
6X19 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | CHU-128 | - | Gs/&β;1/&γ;2 | 2.1 | 2020-09-09 | 10.1016/j.molcel.2020.09.020 | |
6X1A | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Danuglipron | - | Gs/&β;1/&γ;2 | 2.5 | 2020-09-09 | 10.1016/j.molcel.2020.09.020 | |
6XOX | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Orforglipron | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 3.1 | 2020-11-18 | 10.1073/pnas.2014879117 | |
7C2E | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | PubChem 149050799 | - | Gs/&β;1/&γ;2 | 4.2 | 2020-08-26 | 10.1038/s41422-020-0384-8 | |
7DUQ | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | GLP-1 | PubChem 156022738 | Gs/&β;1/&γ;2 | 2.5 | 2021-07-14 | 10.1038/s41467-021-24058-z | |
7DUR | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PubChem 156022738 | Gs/&β;1/&γ;2 | 3.3 | 2021-08-11 | 10.1038/s41467-021-24058-z | |
7E14 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Orforglipron | PubChem 156022738 | Gs/&β;1/&γ;2 | 2.9 | 2021-07-07 | 10.1038/s41467-021-24058-z | |
7EVM | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | PubChem 156022738 | Gs/&β;1/&γ;2 | 2.5 | 2021-08-11 | 10.1038/s41467-021-24058-z | |
7FIM | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Tirzepatide | - | Gs/&β;1/&γ;2 | 3.4 | 2022-03-02 | 10.1038/s41467-022-28683-0 | |
7KI0 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Semaglutide | - | Gs/&β;1/&γ;2 | 2.5 | 2021-08-04 | 10.1016/j.celrep.2021.109374 | |
7KI1 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Taspoglutide | - | Gs/&β;1/&γ;2 | 2.5 | 2021-08-04 | 10.1016/j.celrep.2021.109374 | |
7LCI | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Danuglipron | - | Gs/&β;1/&γ;2 | 2.9 | 2021-01-20 | 10.1016/j.str.2021.04.008 | |
7LCJ | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Danuglipron | - | - | 2.82 | 2021-01-20 | 10.1016/j.str.2021.04.008 | |
7LCK | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Danuglipron | - | - | 3.24 | 2021-01-20 | 10.1016/j.str.2021.04.008 | |
7LLL | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Exendin-4 | - | Gs/&β;1/&γ;2 | 3.7 | 2022-01-12 | 10.1038/s41467-021-27760-0 | |
7LLY | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Oxyntomodulin | - | Gs/&β;1/&γ;2 | 3.3 | 2022-01-12 | 10.1038/s41467-021-27760-0 | |
7RG9 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 3.2 | 2022-04-13 | 10.1073/pnas.2116506119 | |
7RGP | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Tirzepatide | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 2.9 | 2022-04-13 | 10.1073/pnas.2116506119 | |
7RTB | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Peptide-19 | - | Gs/&β;1/&γ;2 | 2.14 | 2021-10-06 | 10.1016/j.bbrc.2021.09.016 | |
7S15 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | PubChem 134611223 | - | - | 3.8 | 2022-06-08 | 10.1021/acs.jmedchem.1c01856 | |
7S1M | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Ex4-D-Ala | - | Gs/&β;1/&γ;2 | 2.41 | 2022-01-05 | 10.1038/s41589-021-00945-w | |
7S3I | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | - | Gs/&β;1/&γ;2 | 2.51 | 2022-01-05 | 10.1038/s41589-021-00945-w | |
7VBH | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Peptide-20 | - | Gs/&β;1/&γ;2 | 3 | 2022-04-06 | 10.1038/s41467-022-28683-0 | |
7VBI | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Non-Acylated Tirzepatide | - | Gs/&β;1/&γ;2 | 3 | 2022-03-02 | 10.1038/s41467-022-28683-0 | |
7X8R | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | BOC5 | - | Gs/&β;1/&γ;2 | 2.61 | 2022-06-29 | 10.1073/pnas.2200155119 | |
7X8S | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | WB4-24 | - | Gs/&β;1/&γ;2 | 3.09 | 2022-06-29 | 10.1073/pnas.2200155119 | |
8JIP | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | MEDI0382 | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 2.85 | 2023-09-06 | 10.1073/pnas.2303696120 | |
8JIR | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | SAR425899 | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 2.57 | 2023-09-06 | 10.1073/pnas.2303696120 | |
8JIS | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | Peptide-15 | - | chim(NtGi1-Gs)/&β;1/&γ;2 | 2.46 | 2023-11-08 | 10.1073/pnas.2303696120 | |
8WG7 | B1 | Peptide | Glucagon | GLP-1 | Homo sapiens | - | - | Gs/&β;1/&γ;2 | 2.54 | 2024-03-06 | 10.1038/s41421-024-00649-0 | |
7D68 | B1 | Peptide | Glucagon | GLP-2 | Homo sapiens | GLP-2 | - | Gs/&β;1/&γ;2 | 3 | 2020-12-16 | 10.1038/s41422-020-00442-0 | |
4L6R | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | - | - | 3.3 | 2013-07-24 | 10.1038/nature12393 | |
5EE7 | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | MK0893 | - | 2.5 | 2016-04-20 | 10.1038/nature17414 | |
5XEZ | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | NNC0640 | - | 3 | 2017-05-24 | 10.1038/nature22363 | |
5XF1 | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | NNC0640 | - | 3.19 | 2017-05-24 | 10.1038/nature22363 | |
5YQZ | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon analogue | - | - | 3 | 2018-01-17 | 10.1038/nature25153 | |
6LMK | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon | - | Gs/&β;1/&γ;2 | 3.7 | 2020-04-01 | 10.1126/science.aaz5346 | |
6LML | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon | - | - | 3.9 | 2020-04-01 | 10.1126/science.aaz5346 | |
6WHC | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glu16 analog of GCG | - | Gs/&β;1/&γ;2 | 3.4 | 2020-05-27 | 10.1074/jbc.RA120.013793 | |
6WPW | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon derivative ZP3780 | - | Gs/&β;1/&γ;2 | 3.1 | 2020-08-12 | 10.1126/science.aba3373 | |
7V35 | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Peptide-20 | - | Gs/&β;1/&γ;2 | 3.5 | 2022-03-02 | 10.1038/s41467-022-28683-0 | |
8FU6 | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon derivative ZP3780 | - | Gs/&β;1/&γ;2 | 2.9 | 2023-04-12 | 10.1016/j.cell.2023.02.028 | |
8JIQ | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Peptide-15 | - | Gs/&β;1/&γ;2 | 3.4 | 2023-09-13 | 10.1073/pnas.2303696120 | |
8JIT | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | MEDI0382 | - | Gs/&β;1/&γ;2 | 2.91 | 2023-09-06 | 10.1073/pnas.2303696120 | |
8JIU | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | SAR425899 | - | Gs/&β;1/&γ;2 | 2.76 | 2023-09-13 | 10.1073/pnas.2303696120 | |
8JRU | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | - | Arrestin2 | 3.5 | 2023-08-16 | 10.1038/s41586-023-06420-x | |
8JRV | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon | - | Arrestin2 | 3.3 | 2023-08-16 | 10.1038/s41586-023-06420-x | |
8WG8 | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | Peptide | chim(NtGi1-Gs)/&β;1/&γ;2 | 2.71 | 2024-03-06 | 10.1038/s41421-024-00649-0 | |
6WI9 | B1 | Peptide | Glucagon | Secretin | Homo sapiens | Secretin | - | Gs/&β;1/&γ;2 | 4.3 | 2020-08-12 | 10.1038/s41467-020-17791-4 | |
6WZG | B1 | Peptide | Glucagon | Secretin | Homo sapiens | Secretin | - | Gs/&β;1/&γ;2 | 2.3 | 2020-08-12 | 10.1038/s41467-020-17791-4 | |
7D3S | B1 | Peptide | Glucagon | Secretin | Homo sapiens | Secretin | - | Gs/&β;1/&γ;2 | 2.9 | 2020-11-04 | 10.1016/j.bbrc.2020.08.042 |
You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).
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You can also read or download a guide explaining the meaning of all files and numerical data.