Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:Y1 5.534540
2L:L:Q3 6.3125420
3L:L:F6 6.985420
4L:L:Y10 7.7625420
5L:L:?13 5.674500
6L:L:Q19 4.7375410
7L:L:F22 6.256510
8R:R:M29 4.665415
9R:R:F33 6.648504
10R:R:W36 4.87667616
11R:R:Y39 6.08516
12R:R:F62 5.496517
13R:R:Y65 6.56429716
14R:R:W68 4.6975469
15R:R:P82 7.2418
16R:R:W83 3.8525402
17R:R:Y84 5.405615
18R:R:R94 7.422585
19R:R:W106 5.78571769
20R:R:P110 5.93503
21R:R:C121 6.645409
22R:R:Y138 6.296525
23R:R:Q142 8.73425
24R:R:Y145 7.285627
25R:R:Y149 6.92286728
26R:R:L153 3.8525406
27R:R:L163 4.9325408
28R:R:K168 6.13558
29R:R:N174 6.625459
30R:R:N179 7.8875438
31R:R:L180 6.31409
32R:R:F184 8.13667608
33R:R:R201 9.45474
34R:R:Y202 7.4325471
35R:R:W215 10.51472
36R:R:R225 11.065498
37R:R:M231 4.7575406
38R:R:Q232 6.91447
39R:R:Y233 4.02639
40R:R:N238 8.2425409
41R:R:W241 11.858539
42R:R:L243 3.93408
43R:R:E245 11.1409
44R:R:F264 5.32536
45R:R:W272 8.4825439
46R:R:P275 4.33833639
47R:R:W282 10.5225449
48R:R:E290 6.31754116
49R:R:W295 9.376599
50R:R:F303 10.434114
51R:R:W304 9.77333646
52R:R:R308 12.5175446
53R:R:F322 3.802509
54R:R:H340 8.865405
55R:R:L354 5.36409
56R:R:E362 5.885408
57R:R:C401 3.9575409
58R:R:E410 5.134558
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1L:L:D9 R:R:Y138 10.28295.75NoYes005
2R:R:M231 R:R:Q232 14.13914.08YesYes067
3L:L:T7 R:R:M231 17.53414.52NoYes006
4L:L:Q3 L:L:T7 22.44684.25YesNo000
5L:L:F6 R:R:Y145 48.86397.22YesYes207
6R:R:Y145 R:R:Y149 87.87747.94YesYes278
7L:L:Q3 R:R:Y149 16.82357.89YesYes208
8L:L:L14 L:L:Y10 92.538210.55NoYes000
9L:L:Y10 R:R:Q142 43.10412.4YesYes205
10L:L:L14 R:R:Y202 96.673914.07NoYes001
11R:R:L216 R:R:W215 93.94685.69NoYes022
12R:R:W215 R:R:Y202 89.7615.79YesYes721
13R:R:F33 R:R:L216 86.3616.09YesNo042
14R:R:F33 R:R:W36 75.40264.01YesYes046
15L:L:I23 R:R:L85 12.60644.28NoNo006
16R:R:L85 R:R:Y65 13.6395.86NoYes066
17R:R:Y65 R:R:Y84 56.27944.96YesYes165
18R:R:W36 R:R:Y84 72.06658.68YesYes165
19R:R:Y39 R:R:Y84 14.09525.96YesYes165
20R:R:C121 R:R:Y65 39.59625.38YesYes096
21R:R:C121 R:R:R94 38.393113.93YesYes095
22R:R:R94 R:R:V96 28.32085.23YesNo857
23R:R:I79 R:R:V96 27.3376.14NoNo047
24R:R:I79 R:R:K98 26.31684.36NoNo048
25R:R:K98 R:R:W68 25.29423.48NoYes089
26R:R:W106 R:R:W68 15.90244.69YesYes699
27R:R:K187 R:R:Y149 1004.78NoYes088
28R:R:K187 R:R:N238 99.87728.39NoYes089
29R:R:F184 R:R:N238 41.640214.5YesYes089
30R:R:F184 R:R:V396 19.57695.24YesNo089
31R:R:F181 R:R:V396 18.98163.93NoNo089
32R:R:F181 R:R:L163 17.17823.65NoYes088
33R:R:L163 R:R:N174 10.39569.61YesYes089
34R:R:N238 R:R:S183 40.35825.96YesNo099
35R:R:S183 R:R:W241 21.6567.41NoYes099
36R:R:L180 R:R:S183 25.52864.5YesNo099
37R:R:E245 R:R:L180 71.999.28YesYes099
38R:R:F184 R:R:L180 30.68067.31YesYes089
39R:R:L242 R:R:N238 22.8984.12NoYes099
40R:R:L180 R:R:L242 22.20624.15YesNo099
41R:R:W241 R:R:W272 12.45117.81YesYes399
42R:R:Q232 R:R:W282 10.19519.86YesYes479
43R:R:K286 R:R:W282 10.87949.28NoYes089
44R:R:W272 R:R:Y233 12.39086.75YesYes399
45R:R:E245 R:R:L357 68.895813.25YesNo099
46R:R:L354 R:R:L357 63.36652.77YesNo099
47R:R:L354 R:R:L358 17.78988.3YesNo099
48R:R:L358 R:R:N318 16.3218.24NoNo099
49R:R:F322 R:R:L354 38.05476.09YesYes099
50R:R:F322 R:R:V326 23.60483.93YesNo097
51R:R:V326 R:R:V330 22.14611.6NoNo076
52R:R:R334 R:R:V330 20.68483.92NoNo076
53R:R:K344 R:R:R334 19.2217.43NoNo067
54R:R:H340 R:R:K344 17.78985.24YesNo056
55R:R:Q142 R:R:Y145 43.48510.15YesYes257
56L:L:F6 L:L:Y10 46.52044.13YesYes200
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:Y1 R:R:I235 4.84 4 Yes No 0 5 0 1
L:L:Y1 R:R:W304 10.61 4 Yes Yes 0 6 0 1
L:L:Y1 R:R:R308 4.12 4 Yes Yes 0 6 0 1
L:L:?2 R:R:D385 14.3 0 No No 0 7 0 1
L:L:?2 R:R:L386 7.95 0 No No 0 7 0 1
L:L:Q3 R:R:Y145 4.51 2 Yes Yes 0 7 0 1
L:L:Q3 R:R:Y149 7.89 2 Yes Yes 0 8 0 1
L:L:Q3 R:R:V191 8.6 2 Yes No 0 7 0 1
L:L:T5 R:R:D370 10.12 0 No No 0 4 0 1
L:L:F6 R:R:Y138 9.28 2 Yes Yes 0 5 0 1
L:L:F6 R:R:Y145 7.22 2 Yes Yes 0 7 0 1
L:L:F6 R:R:L386 7.31 2 Yes No 0 7 0 1
L:L:T7 R:R:M231 4.52 0 No Yes 0 6 0 1
L:L:S8 R:R:N298 8.94 0 No No 0 6 0 1
L:L:D9 R:R:Y138 5.75 0 No Yes 0 5 0 1
L:L:Y10 R:R:Y138 3.97 2 Yes Yes 0 5 0 1
L:L:Y10 R:R:Q142 12.4 2 Yes Yes 0 5 0 1
L:L:S11 R:R:L198 4.5 0 No No 0 6 0 1
L:L:S11 R:R:T296 7.99 0 No No 0 5 0 1
L:L:I12 R:R:S297 4.64 0 No No 0 4 0 1
L:L:?13 R:R:Y138 6.17 0 Yes Yes 0 5 0 1
L:L:L14 R:R:Y202 14.07 0 No Yes 0 1 0 1
L:L:D15 R:R:M29 4.16 1 No Yes 0 5 0 1
L:L:D15 R:R:Q293 7.83 1 No No 0 4 0 1
L:L:K16 R:R:Q131 5.42 0 No No 0 3 0 1
L:L:K17 R:R:A135 4.82 0 No No 0 3 0 1
L:L:Q19 R:R:V28 4.3 1 Yes No 0 3 0 1
L:L:Q19 R:R:M29 5.44 1 Yes Yes 0 5 0 1
L:L:Q19 R:R:L32 3.99 1 Yes No 0 4 0 1
L:L:F22 R:R:M29 4.98 1 Yes Yes 0 5 0 1
L:L:F22 R:R:L32 7.31 1 Yes No 0 4 0 1
L:L:F22 R:R:W36 4.01 1 Yes Yes 0 6 0 1
L:L:F22 R:R:V212 5.24 1 Yes No 0 3 0 1
L:L:I23 R:R:L85 4.28 0 No No 0 6 0 1
L:L:I23 R:R:W87 4.7 0 No No 0 3 0 1
L:L:Y25 R:R:I206 7.25 0 No No 0 4 0 1
L:L:Y25 R:R:G207 5.79 0 No No 0 1 0 1
L:L:L26 R:R:W36 5.69 1 No Yes 0 6 0 1
L:L:L26 R:R:Y84 4.69 1 No Yes 0 5 0 1
L:L:L27 R:R:Y65 7.03 0 No Yes 0 6 0 1
R:R:M29 R:R:Q293 4.08 1 Yes No 5 4 1 1
R:R:D30 R:R:Q293 6.53 0 No No 5 4 2 1
R:R:F33 R:R:W36 4.01 0 Yes Yes 4 6 2 1
R:R:F33 R:R:V212 10.49 0 Yes No 4 3 2 1
R:R:K64 R:R:W36 4.64 0 No Yes 4 6 2 1
R:R:W36 R:R:Y84 8.68 1 Yes Yes 6 5 1 1
R:R:S66 R:R:Y39 3.82 0 No Yes 5 6 2 2
R:R:P82 R:R:Y39 9.74 1 Yes Yes 8 6 2 2
R:R:Y39 R:R:Y84 5.96 1 Yes Yes 6 5 2 1
R:R:S66 R:R:Y65 7.63 0 No Yes 5 6 2 1
R:R:P82 R:R:Y65 8.34 1 Yes Yes 8 6 2 1
R:R:Y65 R:R:Y84 4.96 1 Yes Yes 6 5 1 1
R:R:L85 R:R:Y65 5.86 0 No Yes 6 6 1 1
R:R:W115 R:R:Y65 6.75 0 No Yes 4 6 2 1
R:R:C121 R:R:Y65 5.38 0 Yes Yes 9 6 2 1
R:R:P82 R:R:Y84 6.95 1 Yes Yes 8 5 2 1
R:R:P86 R:R:W87 8.11 0 No No 3 3 2 1
R:R:M123 R:R:W87 10.47 0 No No 3 3 2 1
R:R:V134 R:R:Y138 6.31 0 No Yes 2 5 2 1
R:R:Q142 R:R:Y145 10.15 2 Yes Yes 5 7 1 1
R:R:D195 R:R:Q142 6.53 2 No Yes 7 5 2 1
R:R:Q142 R:R:R199 5.84 2 Yes No 5 4 1 2
R:R:Y145 R:R:Y149 7.94 2 Yes Yes 7 8 1 1
R:R:D195 R:R:Y145 9.2 2 No Yes 7 7 2 1
R:R:L386 R:R:Y145 4.69 2 No Yes 7 7 1 1
R:R:K187 R:R:Y149 4.78 0 No Yes 8 8 2 1
R:R:A188 R:R:Y149 5.34 0 No Yes 8 8 2 1
R:R:V191 R:R:Y149 11.36 2 No Yes 7 8 1 1
R:R:S390 R:R:Y149 7.63 2 No Yes 9 8 2 1
R:R:M231 R:R:S190 4.6 0 Yes No 6 5 1 2
R:R:I194 R:R:M231 5.83 0 No Yes 6 6 2 1
R:R:R201 R:R:Y202 7.2 7 Yes Yes 4 1 2 1
R:R:R201 R:R:W215 23.99 7 Yes Yes 4 2 2 2
R:R:W215 R:R:Y202 5.79 7 Yes Yes 2 1 2 1
R:R:I206 R:R:V212 4.61 0 No No 4 3 1 1
R:R:M231 R:R:Q232 4.08 0 Yes Yes 6 7 1 2
R:R:Q232 R:R:W304 4.38 4 Yes Yes 7 6 2 1
R:R:L307 R:R:Q232 9.32 4 No Yes 7 7 2 2
R:R:N298 R:R:W304 22.6 0 No Yes 6 6 1 1
R:R:L307 R:R:W304 4.56 4 No Yes 7 6 2 1
R:R:R308 R:R:W304 13 4 Yes Yes 6 6 1 1
R:R:R308 R:R:W305 26.99 4 Yes No 6 7 1 2
R:R:D370 R:R:R308 5.96 0 No Yes 4 6 1 1
R:R:D385 R:R:E362 7.8 0 No Yes 7 8 1 2
R:R:D385 R:R:F365 14.33 0 No No 7 7 1 2
R:R:L192 R:R:Y149 3.52 0 No Yes 7 8 2 1
R:R:M301 R:R:W304 3.49 0 No Yes 5 6 2 1
R:R:C294 R:R:T296 3.38 0 No No 9 5 2 1
R:R:D208 R:R:G207 3.35 0 No No 4 1 2 1
L:L:T7 R:R:T296 3.14 0 No No 0 5 0 1
L:L:?2 R:R:S389 2.88 0 No No 0 6 0 1
L:L:A18 R:R:Y202 2.67 0 No Yes 0 1 0 1
R:R:D209 R:R:W36 2.23 0 No Yes 4 6 2 1
R:R:A373 R:R:D370 1.54 0 No No 3 4 2 1
R:R:K35 R:R:Y84 1.19 0 No Yes 4 5 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8YW5_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.71
Number of Linked Nodes 372
Number of Links 413
Number of Hubs 58
Number of Links mediated by Hubs 220
Number of Communities 11
Number of Nodes involved in Communities 67
Number of Links involved in Communities 85
Path Summary
Number Of Nodes in MetaPath 57
Number Of Links MetaPath 56
Number of Shortest Paths 139470
Length Of Smallest Path 3
Average Path Length 18.1401
Length of Longest Path 41
Minimum Path Strength 1.27
Average Path Strength 7.07835
Maximum Path Strength 20.8633
Minimum Path Correlation 0.71
Average Path Correlation 0.95415
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 3.33333
Average % Of Corr. Nodes 54.637
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 54.5387
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• FnI-like domain   • G protein-coupled receptor-like   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• FnI-like domain   • G protein-coupled receptor-like   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeAIB
PDB ResiduesL:L:?2 L:L:?20
Environment DetailsOpen EMBL-EBI Page
CodeAIB
Name2-aminoisobutyric acid
Synonymsα,α-dimethylglycine
Identifier
FormulaC4 H9 N O2
Molecular Weight103.12
SMILES
PubChem5245672
Formal Charge0
Total Atoms16
Total Chiral Atoms0
Total Bonds15
Total Aromatic Bonds0

Code2ML
PDB ResiduesL:L:?13
Environment DetailsOpen EMBL-EBI Page
Code2ML
Namealpha-Methylleucine
Synonyms
  • alpha-Methylleucine
  • (S)-2-Methylleucine
  • 2-Methyl-L-leucine
Identifier
FormulaC7 H15 N O2
Molecular Weight145.199
SMILES
PubChem6951130
Formal Charge0
Total Atoms25
Total Chiral Atoms1
Total Bonds24
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP47871
Sequence
>8YW5_nogp_Chain_R
VMDFLFEKW KLYGDQCHH NLVCNRTFD KYSCWPDAN ISCPWYLPW 
HHKVQHRFV FKRCGPDGQ WVRGPRGQP WRDASQCQM DGEEIEVQK 
EVAKMYSSF QVMYTVGYS LSLGALLLA LAILGGLSK LHCTRNAIH 
ANLFASFVL KASSVLVID GLLRTRYSQ KIGDDLSVS TWLSDGAVA 
GCRVAAVFM QYGIVANYC WLLVEGLYL HNLLGLATL PERSFFSLY 
LGIGWGAPM LFVVPWAVV KCLFENVQC WTSNDNMGF WWILRFPVF 
LAILINFFI FVRIVQLLV AKLRARQMH HTDYKFRLA KSTLTLIPL 
LGVHEVVFA FVTDEHAQG TLRSAKLFF DLFLSSFQG LLVAVLYCF 
LNKEVQSEL RRRWHRWRL G


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9IVMB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)LSN3318839chim(NtGi1-Gs)/β2/γ23.222024-11-1310.1016/j.apsb.2024.09.002
9IVM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)LSN33188393.222024-11-1310.1016/j.apsb.2024.09.002
8YW4B1PeptideGlucagonGIPHomo sapiensRetatrutide-chim(NtGi1-Gs)/β1/γ223.262024-09-18doi.org/10.1038/s41421-024-00700-0
8YW4 (No Gprot) B1PeptideGlucagonGIPHomo sapiensRetatrutide-3.262024-09-18doi.org/10.1038/s41421-024-00700-0
8YW3B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-Gs/β1/γ22.682024-09-18doi.org/10.1038/s41421-024-00700-0
8YW3 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-2.682024-09-18doi.org/10.1038/s41421-024-00700-0
8YW5B1PeptideGlucagonGlucagonHomo sapiensRetatrutide-Gs/β1/γ22.842024-09-18doi.org/10.1038/s41421-024-00700-0
8YW5 (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensRetatrutide-2.842024-09-18doi.org/10.1038/s41421-024-00700-0
8WG8B1PeptideGlucagonGlucagonHomo sapiens-Peptidechim(NtGi1-Gs)/β1/γ22.712024-03-0610.1038/s41421-024-00649-0
8WG8 (No Gprot) B1PeptideGlucagonGlucagonHomo sapiens-Peptide2.712024-03-0610.1038/s41421-024-00649-0
8WA3B1PeptideGlucagonGIPHomo sapiens--Gs/β1/γ22.862024-03-0610.1038/s41421-024-00649-0
8WA3 (No Gprot) B1PeptideGlucagonGIPHomo sapiens--2.862024-03-0610.1038/s41421-024-00649-0
8WG7B1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ22.542024-03-0610.1038/s41421-024-00649-0
8WG7 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--2.542024-03-0610.1038/s41421-024-00649-0
8JISB1PeptideGlucagonGLP-1Homo sapiensPeptide-15-chim(NtGi1-Gs)/β1/γ22.462023-11-0810.1073/pnas.2303696120
8JIS (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-15-2.462023-11-0810.1073/pnas.2303696120
8ITMB1PeptideGlucagonGIPHomo sapiens--Gs/β1/γ23.132023-10-1810.1073/pnas.2306145120
8ITM (No Gprot) B1PeptideGlucagonGIPHomo sapiens--3.132023-10-1810.1073/pnas.2306145120
8ITLB1PeptideGlucagonGIPHomo sapiens--Gs/β1/γ23.232023-10-1810.1073/pnas.2306145120
8ITL (No Gprot) B1PeptideGlucagonGIPHomo sapiens--3.232023-10-1810.1073/pnas.2306145120
8JIRB1PeptideGlucagonGLP-1Homo sapiensSAR425899-chim(NtGi1-Gs)/β1/γ22.572023-09-0610.1073/pnas.2303696120
8JIR (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensSAR425899-2.572023-09-0610.1073/pnas.2303696120
8JIPB1PeptideGlucagonGLP-1Homo sapiensMEDI0382-chim(NtGi1-Gs)/β1/γ22.852023-09-0610.1073/pnas.2303696120
8JIP (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensMEDI0382-2.852023-09-0610.1073/pnas.2303696120
8JITB1PeptideGlucagonGlucagonHomo sapiensMEDI0382-Gs/β1/γ22.912023-09-0610.1073/pnas.2303696120
8JIT (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensMEDI0382-2.912023-09-0610.1073/pnas.2303696120
8JRVB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Arrestin23.32023-08-1610.1038/s41586-023-06420-x
8JRUB1PeptideGlucagonGlucagonHomo sapiens--Arrestin23.52023-08-1610.1038/s41586-023-06420-x
8FU6B1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-Gs/β1/γ22.92023-04-1210.1016/j.cell.2023.02.028
8FU6 (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-2.92023-04-1210.1016/j.cell.2023.02.028
9IVGB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ232024-11-2710.1016/j.apsb.2024.09.002
9IVG (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)-32024-11-2710.1016/j.apsb.2024.09.002
9J1PB1PeptideGlucagonGLP-1Homo sapiensg1:Ox-chim(NtGi1-Gs)/β1/γ22.992025-02-2610.1021/jacs.4c12808
9J1P (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensg1:Ox-2.992025-02-2610.1021/jacs.4c12808
8JIUB1PeptideGlucagonGlucagonHomo sapiensSAR425899-Gs/β1/γ22.762023-09-1310.1073/pnas.2303696120
8JIU (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensSAR425899-2.762023-09-1310.1073/pnas.2303696120
8JIQB1PeptideGlucagonGlucagonHomo sapiensPeptide-15-Gs/β1/γ23.42023-09-1310.1073/pnas.2303696120
8JIQ (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensPeptide-15-3.42023-09-1310.1073/pnas.2303696120
7X8SB1PeptideGlucagonGLP-1Homo sapiensWB4-24-Gs/β1/γ23.092022-06-2910.1073/pnas.2200155119
7X8S (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensWB4-24-3.092022-06-2910.1073/pnas.2200155119
7X8RB1PeptideGlucagonGLP-1Homo sapiensBOC5-Gs/β1/γ22.612022-06-2910.1073/pnas.2200155119
7X8R (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensBOC5-2.612022-06-2910.1073/pnas.2200155119
7S15B1PeptideGlucagonGLP-1Homo sapiensPubChem 134611223--3.82022-06-0810.1021/acs.jmedchem.1c01856
7RBTB1PeptideGlucagonGIPHomo sapiensTirzepatidePubChem 163183774chim(NtGi1-Gs)/β1/γ23.082022-04-1310.1073/pnas.2116506119
7RBT (No Gprot) B1PeptideGlucagonGIPHomo sapiensTirzepatidePubChem 1631837743.082022-04-1310.1073/pnas.2116506119
7RA3B1PeptideGlucagonGIPHomo sapiensGIP-chim(NtGi1-Gs)/β1/γ23.242022-04-1310.1073/pnas.2116506119
7RA3 (No Gprot) B1PeptideGlucagonGIPHomo sapiensGIP-3.242022-04-1310.1073/pnas.2116506119
7RGPB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-chim(NtGi1-Gs)/β1/γ22.92022-04-1310.1073/pnas.2116506119
7RGP (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide-2.92022-04-1310.1073/pnas.2116506119
7RG9B1PeptideGlucagonGLP-1Homo sapiens--chim(NtGi1-Gs)/β1/γ23.22022-04-1310.1073/pnas.2116506119
7RG9 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.22022-04-1310.1073/pnas.2116506119
7V9LB1PeptideGlucagonGHRH (SV1)Homo sapiens--chim(NtGi1-Gs)/β1/γ22.62022-04-0610.1073/pnas.2106606118
7V9L (No Gprot) B1PeptideGlucagonGHRH (SV1)Homo sapiens--2.62022-04-0610.1073/pnas.2106606118
7VBHB1PeptideGlucagonGLP-1Homo sapiensPeptide-20-Gs/β1/γ232022-04-0610.1038/s41467-022-28683-0
7VBH (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-20-32022-04-0610.1038/s41467-022-28683-0
7VABB1PeptideGlucagonGIPHomo sapiensNon-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ23.22022-03-0210.1038/s41467-022-28683-0
7VAB (No Gprot) B1PeptideGlucagonGIPHomo sapiensNon-Acylated Tirzepatide-3.22022-03-0210.1038/s41467-022-28683-0
7FIYB1PeptideGlucagonGIPHomo sapiensTirzepatide-Gs/β1/γ23.42022-03-0210.1038/s41467-022-28683-0
7FIY (No Gprot) B1PeptideGlucagonGIPHomo sapiensTirzepatide-3.42022-03-0210.1038/s41467-022-28683-0
7VBIB1PeptideGlucagonGLP-1Homo sapiensNon-Acylated Tirzepatide-Gs/β1/γ232022-03-0210.1038/s41467-022-28683-0
7VBI (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensNon-Acylated Tirzepatide-32022-03-0210.1038/s41467-022-28683-0
7FIMB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-Gs/β1/γ23.42022-03-0210.1038/s41467-022-28683-0
7FIM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide-3.42022-03-0210.1038/s41467-022-28683-0
7V35B1PeptideGlucagonGlucagonHomo sapiensPeptide-20-Gs/β1/γ23.52022-03-0210.1038/s41467-022-28683-0
7V35 (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensPeptide-20-3.52022-03-0210.1038/s41467-022-28683-0
7FINB1PeptideGlucagonGIPHomo sapiensPeptide-20; GGL-Gs/β1/γ23.12022-02-2310.1038/s41467-022-28683-0
7FIN (No Gprot) B1PeptideGlucagonGIPHomo sapiensPeptide-20; GGL-3.12022-02-2310.1038/s41467-022-28683-0
7LLYB1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-Gs/β1/γ23.32022-01-1210.1038/s41467-021-27760-0
7LLY (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-3.32022-01-1210.1038/s41467-021-27760-0
7LLLB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/β1/γ23.72022-01-1210.1038/s41467-021-27760-0
7LLL (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-4-3.72022-01-1210.1038/s41467-021-27760-0
7S3IB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ22.512022-01-0510.1038/s41589-021-00945-w
7S3I (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--2.512022-01-0510.1038/s41589-021-00945-w
7S1MB1PeptideGlucagonGLP-1Homo sapiensEx4-D-Ala-Gs/β1/γ22.412022-01-0510.1038/s41589-021-00945-w
7S1M (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensEx4-D-Ala-2.412022-01-0510.1038/s41589-021-00945-w
7V9MB1PeptideGlucagonGHRH (SV1)Homo sapiensSomatoliberin-Gs/β1/γ23.292021-10-2010.1073/pnas.2106606118
7V9M (No Gprot) B1PeptideGlucagonGHRH (SV1)Homo sapiensSomatoliberin-3.292021-10-2010.1073/pnas.2106606118
7RTBB1PeptideGlucagonGLP-1Homo sapiensPeptide-19-Gs/β1/γ22.142021-10-0610.1016/j.bbrc.2021.09.016
7RTB (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-19-2.142021-10-0610.1016/j.bbrc.2021.09.016
7EVMB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/β1/γ22.52021-08-1110.1038/s41467-021-24058-z
7EVM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-PubChem 1560227382.52021-08-1110.1038/s41467-021-24058-z
7DURB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/β1/γ23.32021-08-1110.1038/s41467-021-24058-z
7DUR (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-PubChem 1560227383.32021-08-1110.1038/s41467-021-24058-z
7DTYB1PeptideGlucagonGIPHomo sapiensGIP-Gs/β1/γ22.982021-08-0410.7554/eLife.68719
7DTY (No Gprot) B1PeptideGlucagonGIPHomo sapiensGIP-2.982021-08-0410.7554/eLife.68719
7KI1B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-Gs/β1/γ22.52021-08-0410.1016/j.celrep.2021.109374
7KI1 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-2.52021-08-0410.1016/j.celrep.2021.109374
7KI0B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-Gs/β1/γ22.52021-08-0410.1016/j.celrep.2021.109374
7KI0 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-2.52021-08-0410.1016/j.celrep.2021.109374
7DUQB1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 156022738Gs/β1/γ22.52021-07-1410.1038/s41467-021-24058-z
7DUQ (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 1560227382.52021-07-1410.1038/s41467-021-24058-z
7E14B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 156022738Gs/β1/γ22.92021-07-0710.1038/s41467-021-24058-z
7E14 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 1560227382.92021-07-0710.1038/s41467-021-24058-z
7LCKB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--3.242021-01-2010.1016/j.str.2021.04.008
7LCJB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--2.822021-01-2010.1016/j.str.2021.04.008
7LCIB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/β1/γ22.92021-01-2010.1016/j.str.2021.04.008
7LCI (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensDanuglipron-2.92021-01-2010.1016/j.str.2021.04.008
7D68B1PeptideGlucagonGLP-2Homo sapiensGLP-2-Gs/β1/γ232020-12-1610.1038/s41422-020-00442-0
7D68 (No Gprot) B1PeptideGlucagonGLP-2Homo sapiensGLP-2-32020-12-1610.1038/s41422-020-00442-0
6XOXB1PeptideGlucagonGLP-1Homo sapiensOrforglipron-chim(NtGi1-Gs)/β1/γ23.12020-11-1810.1073/pnas.2014879117
6XOX (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOrforglipron-3.12020-11-1810.1073/pnas.2014879117
7CZ5B1PeptideGlucagonGHRHHomo sapiensSomatoliberin-Gs/β1/γ22.62020-11-1810.1038/s41467-020-18945-0
7CZ5 (No Gprot) B1PeptideGlucagonGHRHHomo sapiensSomatoliberin-2.62020-11-1810.1038/s41467-020-18945-0
7D3SB1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/β1/γ22.92020-11-0410.1016/j.bbrc.2020.08.042
7D3S (No Gprot) B1PeptideGlucagonSecretinHomo sapiensSecretin-2.92020-11-0410.1016/j.bbrc.2020.08.042
6X1AB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/β1/γ22.52020-09-0910.1016/j.molcel.2020.09.020
6X1A (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensDanuglipron-2.52020-09-0910.1016/j.molcel.2020.09.020
6X19B1PeptideGlucagonGLP-1Homo sapiensCHU-128-Gs/β1/γ22.12020-09-0910.1016/j.molcel.2020.09.020
6X19 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensCHU-128-2.12020-09-0910.1016/j.molcel.2020.09.020
6X18B1PeptideGlucagonGLP-1Homo sapiensGLP-1-Gs/β1/γ22.12020-09-0910.1016/j.molcel.2020.09.020
6X18 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1-2.12020-09-0910.1016/j.molcel.2020.09.020
7C2EB1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-Gs/β1/γ24.22020-08-2610.1038/s41422-020-0384-8
7C2E (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-4.22020-08-2610.1038/s41422-020-0384-8
6WPWB1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-Gs/β1/γ23.12020-08-1210.1126/science.aba3373
6WPW (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-3.12020-08-1210.1126/science.aba3373
6WZGB1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/β1/γ22.32020-08-1210.1038/s41467-020-17791-4
6WZG (No Gprot) B1PeptideGlucagonSecretinHomo sapiensSecretin-2.32020-08-1210.1038/s41467-020-17791-4
6WI9B1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/β1/γ24.32020-08-1210.1038/s41467-020-17791-4
6WI9 (No Gprot) B1PeptideGlucagonSecretinHomo sapiensSecretin-4.32020-08-1210.1038/s41467-020-17791-4
6VCBB1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN3160440Gs/β1/γ23.32020-07-2210.1038/s41589-020-0589-7
6VCB (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN31604403.32020-07-2210.1038/s41589-020-0589-7
6WHCB1PeptideGlucagonGlucagonHomo sapiensGlu16 analog of GCG-Gs/β1/γ23.42020-05-2710.1074/jbc.RA120.013793
6WHC (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensGlu16 analog of GCG-3.42020-05-2710.1074/jbc.RA120.013793
6LMLB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Gi1/β1/γ13.92020-04-0110.1126/science.aaz5346
6LML (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensGlucagon-3.92020-04-0110.1126/science.aaz5346
6LMKB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Gs/β1/γ23.72020-04-0110.1126/science.aaz5346
6LMK (No Gprot) B1PeptideGlucagonGlucagonHomo sapiensGlucagon-3.72020-04-0110.1126/science.aaz5346
6LN2B1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-3.22020-03-1810.1038/s41467-020-14934-5
6ORVB1PeptideGlucagonGLP-1Homo sapiens-TT-OAD2Gs/β1/γ232020-01-0810.1038/s41586-019-1902-z
6ORV (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-TT-OAD232020-01-0810.1038/s41586-019-1902-z
6KK7B1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-3.12019-11-1310.1107/S2052252519013496
6KK1B1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-2.82019-11-1310.1107/S2052252519013496
6KJVB1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-2.82019-11-1310.1107/S2052252519013496
6B3JB1PeptideGlucagonGLP-1Homo sapiensExendin-P5-Gs/β1/γ23.32018-02-2110.1038/nature25773
6B3J (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-P5-3.32018-02-2110.1038/nature25773
5YQZB1PeptideGlucagonGlucagonHomo sapiensGlucagon analogue--32018-01-1710.1038/nature25153
5NX2B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)--3.72017-06-1410.1038/nature22800
5VEWB1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.72017-05-2410.1038/nature22378
5XF1B1PeptideGlucagonGlucagonHomo sapiens-NNC0640-3.192017-05-2410.1038/nature22363
5XEZB1PeptideGlucagonGlucagonHomo sapiens-NNC0640-32017-05-2410.1038/nature22363
5VAIB1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-Gs/β1/γ24.12017-05-2410.1038/nature22394
5VAI (No Gprot) B1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-4.12017-05-2410.1038/nature22394
5VEXB1PeptideGlucagonGLP-1Homo sapiens-NNC0640-32017-05-1710.1038/nature22378
5EE7B1PeptideGlucagonGlucagonHomo sapiens-MK0893-2.52016-04-2010.1038/nature17414
4L6RB1PeptideGlucagonGlucagonHomo sapiens---3.32013-07-2410.1038/nature12393




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