psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:G4	L:L:H1	3.18	No	No	0	0	0
2	L:L:H1	R:R:I235	9.28	No	Yes	0	0	5
3	L:L:H1	R:R:W304	5.29	No	Yes	0	0	6
4	L:L:S2	R:R:L382	3	No	No	0	0	5
5	L:L:S2	R:R:D385	5.89	No	No	0	0	7
6	L:L:S2	R:R:L386	3	No	No	0	0	7
7	L:L:Q3	R:R:Y145	4.51	Yes	Yes	2	0	7
8	L:L:Q3	R:R:Y149	3.38	Yes	Yes	2	0	8
9	L:L:Q3	R:R:V191	2.87	Yes	Yes	2	0	7
10	L:L:Q3	R:R:I235	2.74	Yes	Yes	0	0	5
11	L:L:Q3	R:R:L386	2.66	Yes	No	0	0	7
12	L:L:D9	L:L:T5	2.89	No	No	3	0	0
13	L:L:T5	R:R:D370	7.23	No	No	3	0	4
14	L:L:T5	R:R:R378	2.59	No	Yes	3	0	4
15	L:L:F6	R:R:Y138	5.16	Yes	No	0	0	5
16	L:L:F6	R:R:F141	5.36	Yes	Yes	0	0	6
17	L:L:F6	R:R:Y145	3.09	Yes	Yes	0	0	7
18	L:L:F6	R:R:L386	4.87	Yes	No	0	0	7
19	L:L:K12	L:L:S8	6.12	No	No	0	0	0
20	L:L:S8	R:R:N298	7.45	No	No	0	0	6
21	L:L:D9	R:R:R378	10.72	No	Yes	3	0	4
22	L:L:L14	L:L:Y10	11.72	No	Yes	0	0	0
23	L:L:Y10	R:R:Y138	2.98	Yes	No	0	0	5
24	L:L:Y10	R:R:Q142	6.76	Yes	No	0	0	5
25	L:L:S11	R:R:T296	4.8	No	No	0	0	5
26	L:L:K12	R:R:S297	4.59	No	No	0	0	4
27	L:L:L14	L:L:Y13	3.52	No	Yes	0	0	0
28	L:L:R17	L:L:Y13	10.29	No	Yes	0	0	0
29	L:L:Y13	R:R:V134	2.52	Yes	No	0	0	2
30	L:L:Y13	R:R:A135	2.67	Yes	No	0	0	3
31	L:L:Y13	R:R:Y138	4.96	Yes	No	0	0	5
32	L:L:L14	R:R:Y202	12.89	No	Yes	0	0	1
33	L:L:D15	R:R:V28	5.84	No	No	0	0	3
34	L:L:S16	R:R:P24	3.56	No	No	0	0	5
35	L:L:E20	L:L:R17	9.3	No	No	0	0	0
36	L:L:R17	R:R:Q131	10.51	No	No	0	0	3
37	L:L:R18	R:R:Y202	6.17	No	Yes	0	0	1
38	L:L:R18	R:R:I206	5.01	No	Yes	0	0	4
39	L:L:R18	R:R:W215	14.99	No	Yes	0	0	2
40	L:L:E20	R:R:M123	10.83	No	No	0	0	3
41	L:L:F22	L:L:W25	5.01	No	No	0	0	0
42	L:L:F22	R:R:M29	7.46	No	No	0	0	5
43	L:L:F22	R:R:I206	7.54	No	Yes	0	0	4
44	L:L:K24	L:L:V23	3.04	No	No	0	0	0
45	L:L:V23	R:R:W87	4.9	No	Yes	0	0	3
46	L:L:E27	L:L:K24	12.15	No	No	0	0	0
47	L:L:L26	L:L:W25	3.42	No	No	0	0	0
48	L:L:L26	R:R:W36	3.42	No	Yes	1	0	6
49	L:L:L26	R:R:Y84	4.69	No	Yes	1	0	5
50	L:L:E27	R:R:P114	9.43	No	No	0	0	5
51	L:L:E27	R:R:Q122	7.65	No	No	0	0	3
52	R:R:D299	R:R:S25	4.42	No	No	0	4	4
53	R:R:D30	R:R:Q27	5.22	No	No	0	5	5
54	R:R:Q27	R:R:V292	7.16	No	No	0	5	4
55	R:R:D30	R:R:L216	4.07	No	No	0	5	2
56	R:R:L32	R:R:P86	3.28	No	No	0	4	3
57	R:R:F33	R:R:K37	4.96	No	No	0	4	3
58	R:R:F33	R:R:V212	2.62	No	No	0	4	3
59	R:R:K35	R:R:W83	4.64	No	Yes	0	4	2
60	R:R:W36	R:R:Y84	5.79	Yes	Yes	1	6	5
61	R:R:W115	R:R:W36	7.5	No	Yes	1	4	6
62	R:R:D209	R:R:W36	8.93	No	Yes	0	4	6
63	R:R:W83	R:R:Y39	7.72	Yes	No	0	2	6
64	R:R:Y39	R:R:Y84	6.95	No	Yes	0	6	5
65	R:R:H45	R:R:Q42	13.6	No	No	0	4	5
66	R:R:C121	R:R:C81	7.28	No	No	0	9	9
67	R:R:P82	R:R:Y84	9.74	No	Yes	1	8	5
68	R:R:L85	R:R:P82	3.28	Yes	No	1	6	8
69	R:R:H88	R:R:W83	3.17	No	Yes	0	4	2
70	R:R:L85	R:R:Y84	4.69	Yes	Yes	1	6	5
71	R:R:W115	R:R:Y84	3.86	No	Yes	1	4	5
72	R:R:L85	R:R:P86	3.28	Yes	No	1	6	3
73	R:R:L85	R:R:W87	4.56	Yes	Yes	1	6	3
74	R:R:L85	R:R:P114	4.93	Yes	No	0	6	5
75	R:R:P86	R:R:W87	10.81	No	Yes	1	3	3
76	R:R:M123	R:R:W87	11.63	No	Yes	0	3	3
77	R:R:H88	R:R:Q92	4.95	No	No	0	4	1
78	R:R:H89	R:R:Q92	3.71	No	No	0	5	1
79	R:R:D124	R:R:K90	5.53	No	No	0	2	4
80	R:R:R94	R:R:V91	6.54	No	No	0	5	6
81	R:R:Q120	R:R:R94	5.84	No	No	0	5	5
82	R:R:F95	R:R:V96	6.55	No	No	0	1	7
83	R:R:F95	R:R:K98	3.72	No	No	0	1	8
84	R:R:F97	R:R:R99	11.76	No	No	0	5	3
85	R:R:R116	R:R:W115	5	No	No	0	6	4
86	R:R:Q122	R:R:S119	2.89	No	No	0	3	5
87	R:R:D124	R:R:E126	6.5	No	No	6	2	3
88	R:R:D124	R:R:E127	5.2	No	No	6	2	1
89	R:R:E126	R:R:E127	13.95	No	No	6	3	1
90	R:R:F141	R:R:M137	3.73	Yes	No	0	6	4
91	R:R:M137	R:R:S379	3.07	No	No	0	4	3
92	R:R:F141	R:R:S140	2.64	Yes	No	0	6	4
93	R:R:F141	R:R:F383	5.36	Yes	No	0	6	5
94	R:R:Q142	R:R:Y145	7.89	No	Yes	2	5	7
95	R:R:D195	R:R:Q142	10.44	Yes	No	2	7	5
96	R:R:F383	R:R:M144	6.22	No	No	0	5	6
97	R:R:F387	R:R:M144	3.73	No	No	0	5	6
98	R:R:T146	R:R:Y145	2.5	No	Yes	0	7	7
99	R:R:V191	R:R:Y145	2.52	Yes	Yes	2	7	7
100	R:R:D195	R:R:Y145	6.9	Yes	Yes	2	7	7
101	R:R:F391	R:R:G148	4.52	No	No	0	7	7
102	R:R:A188	R:R:Y149	2.67	No	Yes	0	8	8
103	R:R:V191	R:R:Y149	6.31	Yes	Yes	2	7	8
104	R:R:S390	R:R:Y149	7.63	No	Yes	0	9	8
105	R:R:L153	R:R:V185	4.47	No	No	0	6	8
106	R:R:F181	R:R:L156	4.87	No	Yes	0	8	8
107	R:R:L156	R:R:V185	4.47	Yes	No	0	8	8
108	R:R:F402	R:R:L158	8.53	Yes	No	0	9	5
109	R:R:A159	R:R:C401	3.61	No	No	7	9	9
110	R:R:A159	R:R:F402	2.77	No	Yes	7	9	9
111	R:R:F181	R:R:L160	4.87	No	No	0	8	6
112	R:R:F402	R:R:I162	2.51	Yes	No	0	9	8
113	R:R:L163	R:R:N174	5.49	No	No	0	8	9
114	R:R:C401	R:R:L163	3.17	No	No	0	9	8
115	R:R:L166	R:R:L169	2.77	Yes	No	0	7	9
116	R:R:E410	R:R:L166	5.3	No	Yes	0	8	7
117	R:R:L166	R:R:R414	4.86	Yes	No	0	7	5
118	R:R:E410	R:R:K168	12.15	No	No	0	8	8
119	R:R:E406	R:R:L169	3.98	No	No	0	9	9
120	R:R:T172	R:R:Y248	2.5	No	No	0	7	8
121	R:R:S262	R:R:T172	3.2	No	No	0	5	7
122	R:R:H177	R:R:R173	6.77	No	No	0	9	9
123	R:R:A175	R:R:F264	4.16	No	No	0	6	6
124	R:R:E245	R:R:I176	5.47	Yes	No	0	9	9
125	R:R:F264	R:R:I176	3.77	No	No	0	6	9
126	R:R:E245	R:R:H177	8.62	Yes	No	0	9	9
127	R:R:N179	R:R:W241	13.56	No	Yes	4	8	9
128	R:R:L268	R:R:N179	2.75	No	No	4	5	8
129	R:R:N179	R:R:W272	5.65	No	No	4	8	9
130	R:R:F184	R:R:L180	7.31	Yes	No	0	8	9
131	R:R:E245	R:R:L180	2.65	Yes	No	0	9	9
132	R:R:N238	R:R:S183	5.96	Yes	No	0	9	9
133	R:R:S183	R:R:W241	3.71	No	Yes	0	9	9
134	R:R:F184	R:R:N238	13.29	Yes	Yes	0	8	9
135	R:R:F184	R:R:Q392	5.86	Yes	No	0	8	9
136	R:R:F184	R:R:G393	4.52	Yes	No	0	8	9
137	R:R:F230	R:R:L186	4.87	No	No	0	4	7
138	R:R:I235	R:R:K187	7.27	Yes	No	0	5	8
139	R:R:K187	R:R:N238	8.39	No	Yes	0	8	9
140	R:R:F230	R:R:S190	3.96	No	No	0	4	5
141	R:R:I194	R:R:M231	10.2	No	No	0	6	6
142	R:R:D195	R:R:R199	3.57	Yes	No	0	7	4
143	R:R:C224	R:R:L197	3.17	No	No	0	9	4
144	R:R:R201	R:R:W215	26.99	Yes	Yes	5	4	2
145	R:R:R201	R:R:V221	5.23	Yes	No	0	4	4
146	R:R:Q293	R:R:R201	10.51	No	Yes	5	4	4
147	R:R:D208	R:R:L210	5.43	No	No	0	4	4
148	R:R:D209	R:R:L210	4.07	No	No	0	4	4
149	R:R:L216	R:R:W215	4.56	No	Yes	0	2	2
150	R:R:Q293	R:R:W215	4.38	No	Yes	5	4	2
151	R:R:R225	R:R:V221	6.54	Yes	No	0	8	4
152	R:R:N291	R:R:R225	7.23	No	Yes	8	6	8
153	R:R:R225	R:R:W295	27.99	Yes	Yes	8	8	9
154	R:R:M231	R:R:Q232	2.72	No	Yes	0	6	7
155	R:R:I235	R:R:M231	2.92	Yes	No	0	5	6
156	R:R:Q232	R:R:W282	7.67	Yes	Yes	9	7	9
157	R:R:L307	R:R:Q232	2.66	No	Yes	9	7	7
158	R:R:G234	R:R:Y233	2.9	No	Yes	0	5	9
159	R:R:A237	R:R:Y233	5.34	No	Yes	10	7	9
160	R:R:P275	R:R:Y233	4.17	Yes	Yes	10	9	9
161	R:R:M276	R:R:Y233	3.59	No	Yes	0	3	9
162	R:R:P275	R:R:V236	5.3	Yes	No	0	9	6
163	R:R:A237	R:R:P275	3.74	No	Yes	10	7	9
164	R:R:L242	R:R:N238	4.12	No	Yes	0	9	9
165	R:R:V311	R:R:Y239	3.79	No	No	0	8	8
166	R:R:E362	R:R:Y239	10.1	Yes	No	0	8	8
167	R:R:C240	R:R:P275	3.77	No	Yes	0	6	9
168	R:R:V244	R:R:W241	3.68	No	Yes	0	8	9
169	R:R:G271	R:R:W241	7.04	No	Yes	0	9	9
170	R:R:W241	R:R:W272	17.81	Yes	No	4	9	9
171	R:R:L243	R:R:L247	5.54	Yes	No	0	8	7
172	R:R:A314	R:R:L243	3.15	No	Yes	0	8	8
173	R:R:I317	R:R:L243	4.28	No	Yes	0	6	8
174	R:R:L243	R:R:N318	4.12	Yes	No	0	8	9
175	R:R:V244	R:R:Y267	2.52	No	No	0	8	7
176	R:R:I270	R:R:V244	3.07	No	No	0	7	8
177	R:R:E245	R:R:L357	3.98	Yes	No	0	9	9
178	R:R:L252	R:R:Y248	4.69	No	No	0	8	8
179	R:R:Y248	R:R:Y267	2.98	No	No	0	8	7
180	R:R:I325	R:R:L249	2.85	No	No	0	9	9
181	R:R:H250	R:R:I321	7.95	No	No	0	7	8
182	R:R:L255	R:R:N251	2.75	No	No	0	5	7
183	R:R:L252	R:R:P259	3.28	No	No	0	8	6
184	R:R:L253	R:R:L328	4.15	No	No	0	8	8
185	R:R:L255	R:R:P259	3.28	No	No	0	5	6
186	R:R:L258	R:R:P259	3.28	No	No	0	6	6
187	R:R:F263	R:R:R261	5.34	No	No	0	5	5
188	R:R:I270	R:R:L266	4.28	No	No	0	7	3
189	R:R:L268	R:R:W272	3.42	No	No	4	5	9
190	R:R:F278	R:R:L277	7.31	No	No	0	5	4
191	R:R:F278	R:R:P310	15.89	No	No	0	5	9
192	R:R:P281	R:R:V280	3.53	No	No	0	4	2
193	R:R:K286	R:R:W282	4.64	No	Yes	0	8	9
194	R:R:L307	R:R:W282	12.53	No	Yes	9	7	9
195	R:R:F303	R:R:V285	7.87	No	No	0	4	5
196	R:R:E290	R:R:K286	10.8	No	No	0	6	8
197	R:R:K286	R:R:W295	10.44	No	Yes	0	8	9
198	R:R:C287	R:R:L288	3.17	No	No	0	3	1
199	R:R:C287	R:R:W295	2.61	No	Yes	0	3	9
200	R:R:F289	R:R:L288	7.31	No	No	0	3	1
201	R:R:D299	R:R:E290	2.6	No	No	0	4	6
202	R:R:E290	R:R:F303	4.66	No	No	0	6	4
203	R:R:N291	R:R:W295	5.65	No	Yes	8	6	9
204	R:R:C294	R:R:T296	5.07	No	No	0	9	5
205	R:R:N298	R:R:W304	19.21	No	Yes	0	6	6
206	R:R:F303	R:R:N300	15.71	No	No	0	4	5
207	R:R:E371	R:R:M301	12.18	No	No	0	5	5
208	R:R:G302	R:R:W305	2.81	No	No	0	2	7
209	R:R:L307	R:R:W304	5.69	No	Yes	0	7	6
210	R:R:R308	R:R:W304	13	No	Yes	0	6	6
211	R:R:R308	R:R:W305	20.99	No	No	0	6	7
212	R:R:F312	R:R:W305	3.01	No	No	0	5	7
213	R:R:F309	R:R:P310	4.33	No	No	0	4	9
214	R:R:I317	R:R:L313	5.71	No	No	0	6	3
215	R:R:E362	R:R:I315	4.1	Yes	No	0	8	7
216	R:R:I315	R:R:V363	6.14	No	No	0	7	6
217	R:R:L358	R:R:N318	4.12	No	No	0	9	9
218	R:R:F319	R:R:V323	2.62	No	No	0	7	5
219	R:R:F319	R:R:V360	2.62	No	No	0	7	6
220	R:R:I321	R:R:I325	2.94	No	No	0	8	9
221	R:R:F322	R:R:V326	6.55	Yes	No	0	9	7
222	R:R:F322	R:R:L354	6.09	Yes	No	0	9	9
223	R:R:F322	R:R:I355	2.51	Yes	No	0	9	8
224	R:R:F322	R:R:L358	3.65	Yes	No	0	9	9
225	R:R:Q327	R:R:V323	2.87	No	No	0	8	5
226	R:R:Q327	R:R:R324	4.67	No	No	0	8	8
227	R:R:I325	R:R:L354	2.85	No	No	0	9	9
228	R:R:T351	R:R:V326	3.17	No	No	0	9	7
229	R:R:L329	R:R:S350	3	No	No	0	9	9
230	R:R:L347	R:R:V330	4.47	No	No	0	9	6
231	R:R:L333	R:R:L347	2.77	No	No	0	7	9
232	R:R:K349	R:R:R346	6.19	No	No	0	9	8
233	R:R:R346	R:R:S350	3.95	No	No	0	8	9
234	R:R:L399	R:R:T353	7.37	No	No	0	8	8
235	R:R:I355	R:R:P356	3.39	No	No	0	8	9
236	R:R:L395	R:R:P356	3.28	No	No	0	6	9
237	R:R:L357	R:R:Y400	16.41	No	No	0	9	8
238	R:R:G359	R:R:H361	3.18	No	Yes	0	9	8
239	R:R:V360	R:R:V363	3.21	No	No	0	6	6
240	R:R:E362	R:R:H361	4.92	Yes	Yes	0	8	8
241	R:R:H361	R:R:L388	9	Yes	No	0	8	6
242	R:R:H361	R:R:Q392	8.65	Yes	No	0	8	9
243	R:R:D385	R:R:E362	5.2	No	Yes	0	7	8
244	R:R:F365	R:R:V364	3.93	No	No	11	7	6
245	R:R:F384	R:R:V364	2.62	No	No	11	4	6
246	R:R:F365	R:R:K381	4.96	No	No	0	7	7
247	R:R:F365	R:R:F384	9.65	No	No	11	7	4
248	R:R:L377	R:R:V368	2.98	No	No	0	3	5
249	R:R:E371	R:R:T369	7.06	No	No	0	5	7
250	R:R:H372	R:R:T369	4.11	No	No	0	4	7
251	R:R:D370	R:R:E371	2.6	No	No	0	4	5
252	R:R:D370	R:R:R378	3.57	No	Yes	3	4	4
253	R:R:A373	R:R:R378	4.15	No	Yes	0	3	4
254	R:R:D385	R:R:K381	2.77	No	No	0	7	7
255	R:R:F384	R:R:L388	6.09	No	No	0	4	6
256	R:R:F387	R:R:F391	5.36	No	No	0	5	7
257	R:R:L394	R:R:V398	2.98	No	No	0	5	6
258	R:R:C401	R:R:F402	5.59	No	Yes	7	9	9
259	R:R:E406	R:R:N404	2.63	No	No	0	9	9
260	R:R:N404	R:R:V407	5.91	No	No	0	9	9
261	R:R:K405	R:R:Q408	2.71	No	No	0	6	7
262	R:R:E410	R:R:R413	6.98	No	No	0	8	7
263	R:R:R414	R:R:R417	8.53	No	No	0	5	7
264	R:R:K422	R:R:W418	16.24	No	No	0	5	3
265	R:R:F184	R:R:L156	2.44	Yes	Yes	0	8	8
266	L:L:T29	L:L:W25	2.43	No	No	0	0	0
267	R:R:L382	R:R:R378	2.43	No	Yes	0	5	4
268	R:R:D117	R:R:R99	2.38	No	No	0	7	3
269	R:R:D117	R:R:R116	2.38	No	No	0	7	6
270	R:R:D218	R:R:R225	2.38	No	Yes	0	4	8
271	L:L:Y10	R:R:L198	2.34	Yes	No	0	0	6
272	R:R:F31	R:R:Q27	2.34	No	No	0	4	5
273	R:R:L198	R:R:Y202	2.34	No	Yes	0	6	1
274	R:R:L333	R:R:Y343	2.34	No	No	0	7	7
275	R:R:L399	R:R:Y400	2.34	No	No	0	8	8
276	L:L:D15	R:R:Y202	2.3	No	Yes	0	0	1
277	R:R:H416	R:R:W415	2.12	No	No	0	3	5
278	R:R:G164	R:R:G165	2.11	No	No	0	3	3
279	R:R:C240	R:R:G271	1.96	No	No	0	6	9
280	R:R:A222	R:R:G219	1.95	No	No	0	4	3
281	R:R:A222	R:R:G223	1.95	No	No	0	4	3
282	R:R:C81	R:R:P82	1.88	No	No	0	9	8
283	R:R:A118	R:R:P114	1.87	No	No	0	5	5
284	R:R:A274	R:R:P275	1.87	No	Yes	0	4	9
285	R:R:W415	R:R:W418	1.87	No	No	0	5	3
286	R:R:G26	R:R:S25	1.86	No	No	0	6	4
287	R:R:G393	R:R:S152	1.86	No	No	0	9	9
288	R:R:G219	R:R:S217	1.86	No	No	0	3	4
289	R:R:G148	R:R:V147	1.84	No	No	0	7	5
290	R:R:G393	R:R:V396	1.84	No	No	0	9	9
291	R:R:C224	R:R:C294	1.82	No	No	0	9	9
292	R:R:A159	R:R:A397	1.79	No	No	0	9	8
293	R:R:P356	R:R:V396	1.77	No	No	0	9	9
294	R:R:G125	R:R:I128	1.76	No	No	0	2	2
295	R:R:G207	R:R:I206	1.76	No	Yes	0	1	4
296	R:R:G246	R:R:I321	1.76	No	No	0	9	8
297	R:R:G273	R:R:M276	1.75	No	No	0	6	3
298	R:R:G207	R:R:K205	1.74	No	No	0	1	4
299	R:R:C121	R:R:V91	1.71	No	No	0	9	6
300	R:R:G154	R:R:L153	1.71	No	No	0	4	6
301	R:R:G154	R:R:L157	1.71	No	No	0	4	3
302	R:R:G165	R:R:L166	1.71	No	Yes	0	3	7
303	R:R:A220	R:R:S217	1.71	No	No	0	6	4
304	R:R:G269	R:R:L268	1.71	No	No	0	4	5
305	L:L:A19	R:R:V28	1.7	No	No	0	0	3
306	R:R:A118	R:R:V96	1.7	No	No	0	5	7
307	R:R:A366	R:R:V363	1.7	No	No	0	7	6
308	R:R:D195	R:R:G196	1.68	Yes	No	0	7	3
309	R:R:A228	R:R:T296	1.68	No	No	0	5	5
310	R:R:G375	R:R:Q374	1.64	No	No	0	2	4
311	L:L:S11	R:R:S297	1.63	No	No	0	0	4
312	L:L:S16	R:R:V28	1.62	No	No	0	0	3
313	R:R:S189	R:R:V193	1.62	No	No	0	4	5
314	R:R:S190	R:R:V191	1.62	No	Yes	0	5	7
315	R:R:A348	R:R:K344	1.61	No	No	0	7	6
316	L:L:S11	L:L:T7	1.6	No	No	0	0	0
317	L:L:S28	L:L:T29	1.6	No	No	0	0	0
318	R:R:S217	R:R:T214	1.6	No	No	0	4	1
319	R:R:V279	R:R:V280	1.6	No	No	0	6	2
320	R:R:A155	R:R:L394	1.58	No	No	0	6	5
321	R:R:A397	R:R:L156	1.58	No	Yes	0	8	8
322	R:R:A178	R:R:L160	1.58	No	No	0	7	6
323	R:R:I162	R:R:V407	1.54	No	No	0	8	9
324	R:R:I206	R:R:V212	1.54	Yes	No	0	4	3
325	R:R:L394	R:R:S152	1.5	No	No	0	5	9
326	R:R:L210	R:R:S213	1.5	No	No	0	4	3
327	R:R:L197	R:R:V193	1.49	No	No	0	4	5
328	R:R:L288	R:R:V284	1.49	No	No	0	1	4
329	R:R:L411	R:R:V407	1.49	No	No	0	5	9
330	R:R:C43	R:R:H44	1.47	No	No	0	9	2
331	R:R:L192	R:R:T146	1.47	No	No	0	7	7
332	R:R:D208	R:R:S211	1.47	No	No	0	4	4
333	R:R:L255	R:R:T257	1.47	No	No	0	5	7
334	R:R:I128	R:R:M123	1.46	No	No	0	2	3
335	R:R:G40	R:R:Y39	1.45	No	No	0	4	6
336	R:R:E362	R:R:S389	1.44	Yes	No	0	8	6
337	R:R:E126	R:R:V130	1.43	No	No	0	3	1
338	R:R:Q131	R:R:V130	1.43	No	No	0	3	1
339	R:R:Q232	R:R:V279	1.43	Yes	No	0	7	6
340	R:R:Q204	R:R:T200	1.42	No	No	0	4	3
341	R:R:K332	R:R:L328	1.41	No	No	0	9	8
342	R:R:H170	R:R:S167	1.39	No	No	0	7	8
343	R:R:A366	R:R:F367	1.39	No	No	0	7	5
344	R:R:A220	R:R:R201	1.38	No	Yes	0	6	4
345	R:R:L399	R:R:L403	1.38	No	No	0	8	5
346	R:R:D41	R:R:L38	1.36	No	No	0	4	3
347	R:R:E129	R:R:K132	1.35	No	No	0	1	2
348	R:R:R334	R:R:V330	1.31	No	No	0	7	6
349	R:R:A283	R:R:W282	1.3	No	Yes	0	5	9
350	R:R:R199	R:R:T200	1.29	No	No	0	4	3
351	R:R:H93	R:R:Q92	1.24	No	No	0	4	1
352	R:R:V229	R:R:W282	1.23	No	Yes	0	6	9
353	R:R:F263	R:R:L266	1.22	No	No	0	5	3
354	R:R:K344	R:R:Y343	1.19	No	No	0	6	7
355	R:R:I306	R:R:W282	1.17	No	Yes	0	8	9
356	R:R:L38	R:R:W83	1.14	No	Yes	0	3	2
357	R:R:H416	R:R:R412	1.13	No	No	0	3	5
358	R:R:H416	R:R:R419	1.13	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:Q3	3.232	5	2	0
2	L:L:F6	4.62	4	0	0
3	L:L:Y10	5.95	4	0	0
4	L:L:Y13	4.792	5	0	0
5	R:R:W36	6.41	4	1	6
6	R:R:W83	4.1675	4	0	2
7	R:R:Y84	5.95333	6	1	5
8	R:R:L85	4.148	5	1	6
9	R:R:W87	7.975	4	1	3
10	R:R:F141	4.2725	4	0	6
11	R:R:Y145	4.56833	6	2	7
12	R:R:Y149	4.9975	4	2	8
13	R:R:L156	3.34	4	0	8
14	R:R:L166	3.66	4	0	7
15	R:R:F184	6.684	5	0	8
16	R:R:V191	3.33	4	2	7
17	R:R:D195	5.6475	4	2	7
18	R:R:R201	11.0275	4	5	4
19	R:R:Y202	5.925	4	0	1
20	R:R:I206	3.9625	4	0	4
21	R:R:W215	12.73	4	5	2
22	R:R:R225	11.035	4	8	8
23	R:R:Q232	3.62	4	9	7
24	R:R:Y233	4	4	10	9
25	R:R:I235	5.5525	4	0	5
26	R:R:N238	7.94	4	0	9
27	R:R:W241	9.16	5	4	9
28	R:R:L243	4.2725	4	0	8
29	R:R:E245	5.18	4	0	9
30	R:R:P275	3.77	5	10	9
31	R:R:W282	4.75667	6	9	9
32	R:R:W295	11.6725	4	8	9
33	R:R:W304	10.7975	4	0	6
34	R:R:F322	4.7	4	0	9
35	R:R:H361	6.4375	4	0	8
36	R:R:E362	5.152	5	0	8
37	R:R:R378	4.692	5	3	4
38	R:R:F402	4.85	4	7	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:H1	R:R:I235	22.6496	9.28	No	Yes	0	0	5
2	L:L:H1	R:R:W304	20.7355	5.29	No	Yes	0	0	6
3	L:L:Q3	R:R:I235	100	2.74	Yes	Yes	0	0	5
4	L:L:Q3	R:R:L386	38.8614	2.66	Yes	No	0	0	7
5	L:L:S2	R:R:L386	26.324	3	No	No	0	0	7
6	L:L:S2	R:R:L382	11.7218	3	No	No	0	0	5
7	L:L:S2	R:R:D385	19.4861	5.89	No	No	0	0	7
8	L:L:Q3	R:R:Y145	62.8404	4.51	Yes	Yes	2	0	7
9	R:R:L382	R:R:R378	10.577	2.43	No	Yes	0	5	4
10	L:L:F6	R:R:Y145	35.1069	3.09	Yes	Yes	0	0	7
11	L:L:F6	R:R:L386	50.4108	4.87	Yes	No	0	0	7
12	L:L:F6	R:R:Y138	77.295	5.16	Yes	No	0	0	5
13	L:L:F6	R:R:F141	16.4918	5.36	Yes	Yes	0	0	6
14	R:R:N298	R:R:W304	16.8395	19.21	No	Yes	0	6	6
15	L:L:S8	R:R:N298	15.5809	7.45	No	No	0	0	6
16	L:L:K12	L:L:S8	14.316	6.12	No	No	0	0	0
17	R:R:Q142	R:R:Y145	29.8877	7.89	No	Yes	2	5	7
18	L:L:Y10	R:R:Q142	33.5067	6.76	Yes	No	0	0	5
19	L:L:L14	L:L:Y10	21.9788	11.72	No	Yes	0	0	0
20	L:L:K12	R:R:S297	13.0451	4.59	No	No	0	0	4
21	L:L:S11	R:R:S297	11.768	1.63	No	No	0	0	4
22	L:L:Y13	R:R:Y138	67.8227	4.96	Yes	No	0	0	5
23	L:L:R17	L:L:Y13	63.5821	10.29	No	Yes	0	0	0
24	L:L:L14	R:R:Y202	27.992	12.89	No	Yes	0	0	1
25	L:L:Y10	R:R:L198	20.9325	2.34	Yes	No	0	0	6
26	R:R:L198	R:R:Y202	20.4924	2.34	No	Yes	0	6	1
27	L:L:E20	L:L:R17	55.5562	9.3	No	No	0	0	0
28	L:L:R18	R:R:Y202	41.1263	6.17	No	Yes	0	0	1
29	L:L:R18	R:R:I206	32.248	5.01	No	Yes	0	0	4
30	L:L:R18	R:R:W215	23.8129	14.99	No	Yes	0	0	2
31	R:R:K286	R:R:W282	18.1474	4.64	No	Yes	0	8	9
32	R:R:K286	R:R:W295	14.7746	10.44	No	Yes	0	8	9
33	R:R:R225	R:R:W295	12.3988	27.99	Yes	Yes	8	8	9
34	R:R:R225	R:R:V221	12.3004	6.54	Yes	No	0	8	4
35	R:R:R201	R:R:V221	12.485	5.23	Yes	No	0	4	4
36	R:R:R201	R:R:W215	14.513	26.99	Yes	Yes	5	4	2
37	L:L:E20	R:R:M123	54.3807	10.83	No	No	0	0	3
38	L:L:F22	R:R:I206	23.7914	7.54	No	Yes	0	0	4
39	L:L:F22	L:L:W25	20.9386	5.01	No	No	0	0	0
40	R:R:M123	R:R:W87	50.9678	11.63	No	Yes	0	3	3
41	R:R:L85	R:R:P114	11.6972	4.93	Yes	No	0	6	5
42	R:R:L85	R:R:W87	41.9295	4.56	Yes	Yes	1	6	3
43	L:L:L26	L:L:W25	16.701	3.42	No	No	0	0	0
44	R:R:L85	R:R:Y84	27.3765	4.69	Yes	Yes	1	6	5
45	R:R:Y39	R:R:Y84	14.3376	6.95	No	Yes	0	6	5
46	R:R:W83	R:R:Y39	11.5156	7.72	Yes	No	0	2	6
47	R:R:D209	R:R:W36	11.3525	8.93	No	Yes	0	4	6
48	R:R:I235	R:R:K187	92.4604	7.27	Yes	No	0	5	8
49	R:R:K187	R:R:N238	91.9157	8.39	No	Yes	0	8	9
50	R:R:F184	R:R:N238	69.5276	13.29	Yes	Yes	0	8	9
51	R:R:F184	R:R:L156	34.95	2.44	Yes	Yes	0	8	8
52	R:R:A397	R:R:L156	25.8163	1.58	No	Yes	0	8	8
53	R:R:A159	R:R:A397	24.6469	1.79	No	No	0	9	8
54	R:R:A159	R:R:F402	19.76	2.77	No	Yes	7	9	9
55	R:R:F402	R:R:I162	17.5012	2.51	Yes	No	0	9	8
56	R:R:I162	R:R:V407	16.2887	1.54	No	No	0	8	9
57	R:R:N404	R:R:V407	13.8452	5.91	No	No	0	9	9
58	R:R:E406	R:R:N404	12.6142	2.63	No	No	0	9	9
59	R:R:E406	R:R:L169	11.3771	3.98	No	No	0	9	9
60	R:R:L166	R:R:L169	10.1339	2.77	Yes	No	0	7	9
61	R:R:N238	R:R:S183	39.3784	5.96	Yes	No	0	9	9
62	R:R:S183	R:R:W241	38.2828	3.71	No	Yes	0	9	9
63	R:R:V244	R:R:W241	18.7167	3.68	No	Yes	0	8	9
64	R:R:V244	R:R:Y267	12.6235	2.52	No	No	0	8	7
65	R:R:Y248	R:R:Y267	11.3864	2.98	No	No	0	8	7
66	R:R:F184	R:R:L180	15.0454	7.31	Yes	No	0	8	9
67	R:R:E245	R:R:L180	13.8206	2.65	Yes	No	0	9	9
68	R:R:F184	R:R:Q392	10.2477	5.86	Yes	No	0	8	9
69	R:R:F184	R:R:G393	30.4355	4.52	Yes	No	0	8	9
70	R:R:I235	R:R:M231	22.5912	2.92	Yes	No	0	5	6
71	R:R:M231	R:R:Q232	20.6647	2.72	No	Yes	0	6	7
72	R:R:G271	R:R:W241	12.645	7.04	No	Yes	0	9	9
73	R:R:C240	R:R:G271	11.4079	1.96	No	No	0	6	9
74	R:R:C240	R:R:P275	10.1646	3.77	No	Yes	0	6	9
75	R:R:D385	R:R:E362	16.1933	5.2	No	Yes	0	7	8
76	R:R:G393	R:R:V396	24.6499	1.84	No	No	0	9	9
77	R:R:P356	R:R:V396	23.4744	1.77	No	No	0	9	9
78	R:R:I355	R:R:P356	21.1048	3.39	No	No	0	8	9
79	R:R:F322	R:R:I355	19.9108	2.51	Yes	No	0	9	8
80	R:R:E362	R:R:I315	10.6047	4.1	Yes	No	0	8	7
81	R:R:H361	R:R:Q392	10.1062	8.65	Yes	No	0	8	9
82	R:R:Q232	R:R:W282	16.8888	7.67	Yes	Yes	9	7	9
83	L:L:Y10	R:R:Y138	11.4202	2.98	Yes	No	0	0	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:H1	R:R:I235	9.28	0	No	Yes	0	5	0	1
L:L:H1	R:R:W304	5.29	0	No	Yes	0	6	0	1
L:L:S2	R:R:L382	3	0	No	No	0	5	0	1
L:L:S2	R:R:D385	5.89	0	No	No	0	7	0	1
L:L:S2	R:R:L386	3	0	No	No	0	7	0	1
L:L:Q3	R:R:Y145	4.51	2	Yes	Yes	0	7	0	1
L:L:Q3	R:R:Y149	3.38	2	Yes	Yes	0	8	0	1
L:L:Q3	R:R:V191	2.87	2	Yes	Yes	0	7	0	1
L:L:Q3	R:R:I235	2.74	2	Yes	Yes	0	5	0	1
L:L:Q3	R:R:L386	2.66	2	Yes	No	0	7	0	1
L:L:T5	R:R:D370	7.23	3	No	No	0	4	0	1
L:L:T5	R:R:R378	2.59	3	No	Yes	0	4	0	1
L:L:F6	R:R:Y138	5.16	0	Yes	No	0	5	0	1
L:L:F6	R:R:F141	5.36	0	Yes	Yes	0	6	0	1
L:L:F6	R:R:Y145	3.09	0	Yes	Yes	0	7	0	1
L:L:F6	R:R:L386	4.87	0	Yes	No	0	7	0	1
L:L:S8	R:R:N298	7.45	0	No	No	0	6	0	1
L:L:D9	R:R:R378	10.72	3	No	Yes	0	4	0	1
L:L:Y10	R:R:Y138	2.98	0	Yes	No	0	5	0	1
L:L:Y10	R:R:Q142	6.76	0	Yes	No	0	5	0	1
L:L:S11	R:R:T296	4.8	0	No	No	0	5	0	1
L:L:K12	R:R:S297	4.59	0	No	No	0	4	0	1
L:L:Y13	R:R:V134	2.52	0	Yes	No	0	2	0	1
L:L:Y13	R:R:A135	2.67	0	Yes	No	0	3	0	1
L:L:Y13	R:R:Y138	4.96	0	Yes	No	0	5	0	1
L:L:L14	R:R:Y202	12.89	0	No	Yes	0	1	0	1
L:L:D15	R:R:V28	5.84	0	No	No	0	3	0	1
L:L:S16	R:R:P24	3.56	0	No	No	0	5	0	1
L:L:R17	R:R:Q131	10.51	0	No	No	0	3	0	1
L:L:R18	R:R:Y202	6.17	0	No	Yes	0	1	0	1
L:L:R18	R:R:I206	5.01	0	No	Yes	0	4	0	1
L:L:R18	R:R:W215	14.99	0	No	Yes	0	2	0	1
L:L:E20	R:R:M123	10.83	0	No	No	0	3	0	1
L:L:F22	R:R:M29	7.46	0	No	No	0	5	0	1
L:L:F22	R:R:I206	7.54	0	No	Yes	0	4	0	1
L:L:V23	R:R:W87	4.9	0	No	Yes	0	3	0	1
L:L:L26	R:R:W36	3.42	1	No	Yes	0	6	0	1
L:L:L26	R:R:Y84	4.69	1	No	Yes	0	5	0	1
L:L:E27	R:R:P114	9.43	0	No	No	0	5	0	1
L:L:E27	R:R:Q122	7.65	0	No	No	0	3	0	1
R:R:W36	R:R:Y84	5.79	1	Yes	Yes	6	5	1	1
R:R:W115	R:R:W36	7.5	1	No	Yes	4	6	2	1
R:R:D209	R:R:W36	8.93	0	No	Yes	4	6	2	1
R:R:Y39	R:R:Y84	6.95	0	No	Yes	6	5	2	1
R:R:P82	R:R:Y84	9.74	1	No	Yes	8	5	2	1
R:R:L85	R:R:P82	3.28	1	Yes	No	6	8	2	2
R:R:L85	R:R:Y84	4.69	1	Yes	Yes	6	5	2	1
R:R:W115	R:R:Y84	3.86	1	No	Yes	4	5	2	1
R:R:L85	R:R:P86	3.28	1	Yes	No	6	3	2	2
R:R:L85	R:R:W87	4.56	1	Yes	Yes	6	3	2	1
R:R:L85	R:R:P114	4.93	1	Yes	No	6	5	2	1
R:R:P86	R:R:W87	10.81	1	No	Yes	3	3	2	1
R:R:M123	R:R:W87	11.63	0	No	Yes	3	3	1	1
R:R:Q122	R:R:S119	2.89	0	No	No	3	5	1	2
R:R:F141	R:R:M137	3.73	0	Yes	No	6	4	1	2
R:R:F141	R:R:S140	2.64	0	Yes	No	6	4	1	2
R:R:F141	R:R:F383	5.36	0	Yes	No	6	5	1	2
R:R:Q142	R:R:Y145	7.89	2	No	Yes	5	7	1	1
R:R:D195	R:R:Q142	10.44	2	Yes	No	7	5	2	1
R:R:T146	R:R:Y145	2.5	0	No	Yes	7	7	2	1
R:R:V191	R:R:Y145	2.52	2	Yes	Yes	7	7	1	1
R:R:D195	R:R:Y145	6.9	2	Yes	Yes	7	7	2	1
R:R:A188	R:R:Y149	2.67	0	No	Yes	8	8	2	1
R:R:V191	R:R:Y149	6.31	2	Yes	Yes	7	8	1	1
R:R:S390	R:R:Y149	7.63	0	No	Yes	9	8	2	1
R:R:I235	R:R:K187	7.27	0	Yes	No	5	8	1	2
R:R:R201	R:R:W215	26.99	5	Yes	Yes	4	2	2	1
R:R:Q293	R:R:R201	10.51	5	No	Yes	4	4	2	2
R:R:L216	R:R:W215	4.56	0	No	Yes	2	2	2	1
R:R:Q293	R:R:W215	4.38	5	No	Yes	4	2	2	1
R:R:I235	R:R:M231	2.92	0	Yes	No	5	6	1	2
R:R:C294	R:R:T296	5.07	0	No	No	9	5	2	1
R:R:N298	R:R:W304	19.21	0	No	Yes	6	6	1	1
R:R:L307	R:R:W304	5.69	9	No	Yes	7	6	2	1
R:R:R308	R:R:W304	13	0	No	Yes	6	6	2	1
R:R:D385	R:R:E362	5.2	0	No	Yes	7	8	1	2
R:R:D370	R:R:E371	2.6	3	No	No	4	5	1	2
R:R:D370	R:R:R378	3.57	3	No	Yes	4	4	1	1
R:R:A373	R:R:R378	4.15	0	No	Yes	3	4	2	1
R:R:D385	R:R:K381	2.77	0	No	No	7	7	1	2
R:R:L382	R:R:R378	2.43	0	No	Yes	5	4	1	1
L:L:Y10	R:R:L198	2.34	0	Yes	No	0	6	0	1
R:R:L198	R:R:Y202	2.34	0	No	Yes	6	1	1	1
L:L:D15	R:R:Y202	2.3	0	No	Yes	0	1	0	1
R:R:A118	R:R:P114	1.87	0	No	No	5	5	2	1
R:R:G207	R:R:I206	1.76	0	No	Yes	1	4	2	1
L:L:A19	R:R:V28	1.7	0	No	No	0	3	0	1
R:R:A228	R:R:T296	1.68	0	No	No	5	5	2	1
L:L:S11	R:R:S297	1.63	0	No	No	0	4	0	1
L:L:S16	R:R:V28	1.62	0	No	No	0	3	0	1
R:R:S190	R:R:V191	1.62	0	No	Yes	5	7	2	1
R:R:I206	R:R:V212	1.54	0	Yes	No	4	3	1	2
R:R:I128	R:R:M123	1.46	0	No	No	2	3	2	1
R:R:Q131	R:R:V130	1.43	0	No	No	3	1	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8FU6_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.5
Number of Linked Nodes	343
Number of Links	358
Number of Hubs	38
Number of Links mediated by Hubs	147
Number of Communities	11
Number of Nodes involved in Communities	43
Number of Links involved in Communities	50

Path Summary
Number Of Nodes in MetaPath	84
Number Of Links MetaPath	83
Number of Shortest Paths	69627
Length Of Smallest Path	3
Average Path Length	15.0489
Length of Longest Path	32
Minimum Path Strength	1.13
Average Path Strength	5.80855
Maximum Path Strength	20.99
Minimum Path Correlation	0.7
Average Path Correlation	0.954131
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	62.7485
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.3513
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • glucagon receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • amide binding • peptide hormone binding • hormone binding • GDP binding • nucleoside-triphosphatase regulator activity • GTPase regulator activity • guanyl-nucleotide exchange factor activity • circulatory system process • regulation of blood pressure • blood circulation • regulation of biosynthetic process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • hormone-mediated signaling pathway • carbohydrate metabolic process • energy derivation by oxidation of organic compounds • glycogen metabolic process • primary metabolic process • regulation of generation of precursor metabolites and energy • generation of precursor metabolites and energy • regulation of polysaccharide metabolic process • regulation of primary metabolic process • glucan metabolic process • polysaccharide metabolic process • energy reserve metabolic process • regulation of glycogen metabolic process • regulation of carbohydrate metabolic process • cellular response to nutrient levels • response to nutrient levels • response to starvation • cellular response to starvation • cell surface receptor signaling pathway • response to nutrient • exocytosis • vesicle-mediated transport • glucose homeostasis • carbohydrate homeostasis • endosome • intracellular vesicle • cytoplasmic vesicle
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P47871
Sequence	>8FU6_nogp_Chain_R P S G Q V M D F L F E K W K L Y G D Q C H H C P W Y L P W H H K V Q H R F V F K R C P W R D A S Q C Q M D G E E I E V Q K E V A K M Y S S F Q V M Y T V G Y S L S L G A L L L A L A I L G G L S K L H C T R N A I H A N L F A S F V L K A S S V L V I D G L L R T R Y S Q K I G D D L S V S T W L S D G A V A G C R V A A V F M Q Y G I V A N Y C W L L V E G L Y L H N L L G L A T L P E R S F F S L Y L G I G W G A P M L F V V P W A V V K C L F E N V Q C W T S N D N M G F W W I L R F P V F L A I L I N F F I F V R I V Q L L V A K L R A R Y K F R L A K S T L T L I P L L G V H E V V F A F V T D E H A Q G T L R S A K L F F D L F L S S F Q G L L V A V L Y C F L N K E V Q S E L R R R W H R W R L G K V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	8YW4	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ22	3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW4 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-		3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW5	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.84	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW5 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Retatrutide	-		2.84	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WG8	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide	chim(NtGi1-Gs)/β1/γ2	2.71	2024-03-06	10.1038/s41421-024-00649-0
	8WG8 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide		2.71	2024-03-06	10.1038/s41421-024-00649-0
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	2.86	2024-03-06	10.1038/s41421-024-00649-0
	8WA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		2.86	2024-03-06	10.1038/s41421-024-00649-0
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	10.1038/s41421-024-00649-0
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	10.1073/pnas.2303696120
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.13	2023-10-18	10.1073/pnas.2306145120
	8ITM (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.13	2023-10-18	10.1073/pnas.2306145120
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.23	2023-10-18	10.1073/pnas.2306145120
	8ITL (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.23	2023-10-18	10.1073/pnas.2306145120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	10.1073/pnas.2303696120
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	10.1073/pnas.2303696120
	8JIT	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-	Gs/β1/γ2	2.91	2023-09-06	10.1073/pnas.2303696120
	8JIT (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-		2.91	2023-09-06	10.1073/pnas.2303696120
	8JRV	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Arrestin2	3.3	2023-08-16	10.1038/s41586-023-06420-x
	8JRU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	Arrestin2	3.5	2023-08-16	10.1038/s41586-023-06420-x
	8FU6	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/β1/γ2	2.9	2023-04-12	10.1016/j.cell.2023.02.028
	8FU6 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-		2.9	2023-04-12	10.1016/j.cell.2023.02.028
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	10.1016/j.apsb.2024.09.002
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	10.1021/jacs.4c12808
	8JIU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-	Gs/β1/γ2	2.76	2023-09-13	10.1073/pnas.2303696120
	8JIU (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-		2.76	2023-09-13	10.1073/pnas.2303696120
	8JIQ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-	Gs/β1/γ2	3.4	2023-09-13	10.1073/pnas.2303696120
	8JIQ (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-		3.4	2023-09-13	10.1073/pnas.2303696120
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	10.1073/pnas.2200155119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	10.1073/pnas.2200155119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774	chim(NtGi1-Gs)/β1/γ2	3.08	2022-04-13	10.1073/pnas.2116506119
	7RBT (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774		3.08	2022-04-13	10.1073/pnas.2116506119
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/β1/γ2	3.24	2022-04-13	10.1073/pnas.2116506119
	7RA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		3.24	2022-04-13	10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	10.1073/pnas.2116506119
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	10.1073/pnas.2116506119
	7V9L	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2022-04-06	10.1073/pnas.2106606118
	7V9L (No Gprot)	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-		2.6	2022-04-06	10.1073/pnas.2106606118
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	10.1038/s41467-022-28683-0
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-03-02	10.1038/s41467-022-28683-0
	7VAB (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-		3.2	2022-03-02	10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	10.1038/s41467-022-28683-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7V35	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3.5	2022-03-02	10.1038/s41467-022-28683-0
	7V35 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-		3.5	2022-03-02	10.1038/s41467-022-28683-0
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/β1/γ2	3.1	2022-02-23	10.1038/s41467-022-28683-0
	7FIN (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-		3.1	2022-02-23	10.1038/s41467-022-28683-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	10.1038/s41467-021-27760-0
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	10.1038/s41589-021-00945-w
	7V9M	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-	Gs/β1/γ2	3.29	2021-10-20	10.1073/pnas.2106606118
	7V9M (No Gprot)	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-		3.29	2021-10-20	10.1073/pnas.2106606118
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/β1/γ2	2.98	2021-08-04	10.7554/eLife.68719
	7DTY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		2.98	2021-08-04	10.7554/eLife.68719
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	10.1038/s41467-021-24058-z
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	10.1016/j.str.2021.04.008
	7D68	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-	Gs/β1/γ2	3	2020-12-16	10.1038/s41422-020-00442-0
	7D68 (No Gprot)	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-		3	2020-12-16	10.1038/s41422-020-00442-0
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	10.1073/pnas.2014879117
	7CZ5	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-	Gs/β1/γ2	2.6	2020-11-18	10.1038/s41467-020-18945-0
	7CZ5 (No Gprot)	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-		2.6	2020-11-18	10.1038/s41467-020-18945-0
	7D3S	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	2.9	2020-11-04	10.1016/j.bbrc.2020.08.042
	7D3S (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		2.9	2020-11-04	10.1016/j.bbrc.2020.08.042
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	10.1038/s41422-020-0384-8
	6WPW	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/β1/γ2	3.1	2020-08-12	10.1126/science.aba3373
	6WPW (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-		3.1	2020-08-12	10.1126/science.aba3373
	6WZG	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	2.3	2020-08-12	10.1038/s41467-020-17791-4
	6WZG (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		2.3	2020-08-12	10.1038/s41467-020-17791-4
	6WI9	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	4.3	2020-08-12	10.1038/s41467-020-17791-4
	6WI9 (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		4.3	2020-08-12	10.1038/s41467-020-17791-4
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	10.1038/s41589-020-0589-7
	6WHC	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-	Gs/β1/γ2	3.4	2020-05-27	10.1074/jbc.RA120.013793
	6WHC (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-		3.4	2020-05-27	10.1074/jbc.RA120.013793
	6LML	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gi1/β1/γ1	3.9	2020-04-01	10.1126/science.aaz5346
	6LML (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-		3.9	2020-04-01	10.1126/science.aaz5346
	6LMK	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gs/β1/γ2	3.7	2020-04-01	10.1126/science.aaz5346
	6LMK (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-		3.7	2020-04-01	10.1126/science.aaz5346
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	10.1038/s41586-019-1902-z
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	10.1038/nature25773
	5YQZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon analogue	-	-	3	2018-01-17	10.1038/nature25153
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5XF1	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3.19	2017-05-24	10.1038/nature22363
	5XEZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3	2017-05-24	10.1038/nature22363
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	10.1038/nature22394
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
	5EE7	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	MK0893	-	2.5	2016-04-20	10.1038/nature17414
	4L6R	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	-	3.3	2013-07-24	10.1038/nature12393

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