Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:Y145 4.8665107
2R:R:Y149 5.318577108
3R:R:L153 1.935406
4R:R:L156 3.7325408
5R:R:K168 4.6175498
6R:R:R173 5.53599
7R:R:N174 7.4975499
8R:R:L180 4.255419
9R:R:F181 3.39571718
10R:R:F184 7.10667618
11R:R:D195 5.394107
12R:R:F230 3.2375404
13R:R:Y233 6.8825409
14R:R:Y239 7.65754168
15R:R:W241 8.855619
16R:R:V244 6.542518
17R:R:L249 4.0125409
18R:R:L253 4.185408
19R:R:F263 4.565415
20R:R:Y267 4.775617
21R:R:G271 2.865419
22R:R:W272 2.5625409
23R:R:P275 3.422519
24R:R:W282 8.0165159
25R:R:W295 10.16409
26R:R:R308 4.8175406
27R:R:F312 3.61405
28R:R:I315 3.98254167
29R:R:N318 5.584139
30R:R:K344 7.534176
31R:R:L354 4.38409
32R:R:I355 3.5725138
33R:R:H361 7.39418
34R:R:Q392 5.9125419
35R:R:V396 4.8125419
36R:R:Y400 8.57618
37R:R:E410 4.5598
38R:R:W425 5.26167622
39V:V:N15 4.7785118
40V:V:V20 2.94754126
41V:V:Y21 5.40167658
42V:V:R25 5.51409
43V:V:D26 7.1975409
44V:V:V40 3.475658
45V:V:Y54 8.51534
46V:V:L57 5.485407
47V:V:F61 4.5125429
48V:V:R62 6.5825478
49V:V:D78 5.1478
50V:V:F80 5.15424
51V:V:F87 12.24634
52V:V:P88 6.1325439
53V:V:Q101 3.814559
54V:V:L108 4.754508
55V:V:Y113 5.9075433
56V:V:P114 3.7175458
57V:V:F115 6.0754129
58V:V:F117 6.223336128
59V:V:I119 4.2475405
60V:V:P120 5.4575427
61V:V:L123 3.728526
62V:V:P124 3.64429
63V:V:T128 3.135406
64V:V:L129 4.1375428
65V:V:Q130 5.035409
66V:V:V142 2.6525429
67V:V:Y144 4.5075427
68V:V:F149 7.6375435
69V:V:L166 5.85254128
70V:V:Q172 5.84754239
71V:V:Y173 5.3145224
72V:V:P182 4.8575409
73V:V:L199 3.63754266
74V:V:Y208 5.82566
75V:V:I214 5.83468
76V:V:I233 5.7375485
77V:V:V235 3.678568
78V:V:R236 9.098545
79V:V:Q237 8.5525469
80V:V:Y238 10.235644
81V:V:I241 4.64428
82V:V:L243 5.28527
83V:V:D260 4.7625486
84V:V:F268 4.626585
85V:V:Y272 5.485884
86V:V:L287 4.775407
87V:V:L289 5.24254249
88V:V:K292 5.37254246
89V:V:L293 7.13754218
90V:V:R312 3.5185144
91V:V:I317 5.468528
92V:V:Y321 8.046569
93V:V:K324 5.66546
94V:V:K326 6.1025407
95V:V:L327 4.685407
96V:V:F349 4.25667667
97V:V:H353 9.615408
98V:V:P360 4.2945221
99V:V:?701 7.222540
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:Y145 R:R:Y149 11.15961.99YesYes1078
2R:R:K187 R:R:Y149 27.29082.39NoYes088
3R:R:I235 R:R:K187 27.82775.82NoNo058
4R:R:I235 R:R:Y239 28.36543.63NoYes058
5R:R:V311 R:R:Y239 30.57197.57NoYes088
6R:R:V236 R:R:V311 36.44923.21NoNo068
7R:R:P275 R:R:V236 37.9991.77YesNo096
8R:R:G271 R:R:P275 41.01442.03YesYes199
9R:R:G271 R:R:W241 39.66095.63YesYes199
10R:R:L180 R:R:W241 61.80556.83YesYes199
11R:R:L180 R:R:Y400 69.3912.34YesYes198
12R:R:F181 R:R:Y400 12.98765.16YesYes188
13R:R:F184 R:R:L180 10.99554.87YesYes189
14R:R:V244 R:R:Y267 10.0927.57YesYes187
15R:R:S350 R:R:Y400 92.74325.09NoYes098
16R:R:R346 R:R:S350 93.86336.59NoNo089
17R:R:N404 R:R:R346 94.506819.28NoNo098
18R:R:E406 R:R:N404 94.82643.94NoNo099
19R:R:E406 R:R:K405 95.14462.7NoNo096
20R:R:K405 R:R:Q408 95.46154.07NoNo067
21R:R:Q408 R:R:R412 95.77693.5NoNo075
22R:R:H416 R:R:R412 96.40352.26NoNo035
23R:R:H416 V:V:N245 96.714720.41NoNo038
24V:V:F244 V:V:N245 97.02452.42NoNo088
25V:V:F244 V:V:L243 97.03444.87NoYes287
26V:V:F61 V:V:L243 1006.09YesYes297
27V:V:F61 V:V:I317 56.025.02YesYes298
28V:V:I317 V:V:V127 66.06156.14YesNo088
29V:V:A288 V:V:V127 65.98021.7NoNo098
30V:V:A288 V:V:V319 65.91921.7NoNo098
31V:V:V319 V:V:Y321 45.335.05NoYes689
32V:V:F349 V:V:Y321 42.57616.19YesYes679
33V:V:F349 V:V:Y208 19.11584.13YesYes676
34V:V:L203 V:V:Y208 18.75633.52NoYes086
35V:V:L203 V:V:P182 18.148611.49NoYes089
36V:V:L347 V:V:P182 25.09131.64NoYes069
37V:V:L347 V:V:P348 24.62661.64NoNo069
38V:V:K322 V:V:P348 24.16268.36NoNo059
39V:V:K322 V:V:Y238 14.28510.75NoYes454
40R:R:W272 R:R:Y233 12.90353.86YesYes099
41R:R:W241 R:R:W272 14.64812.81YesYes099
42R:R:V279 R:R:Y233 10.040210.09NoYes069
43R:R:E245 R:R:Y400 10.170510.1NoYes098
44V:V:F61 V:V:V142 44.33753.93YesYes299
45V:V:P124 V:V:V142 53.4981.77YesYes299
46V:V:L123 V:V:P124 48.3984.93YesYes269
47V:V:F80 V:V:L123 42.43662.44YesYes246
48V:V:F80 V:V:L57 21.57682.44YesYes047
49V:V:F117 V:V:L57 28.280512.18YesYes087
50V:V:F115 V:V:F117 48.89435.36YesYes1298
51V:V:F115 V:V:G39 25.78314.52YesNo098
52V:V:G39 V:V:Q101 25.07033.29NoYes089
53V:V:Q101 V:V:V40 14.79812.87YesYes598
54V:V:A82 V:V:F80 21.07644.16NoYes044
55V:V:A82 V:V:F117 20.80232.77NoYes048
56V:V:F115 V:V:V20 34.10882.62YesYes1296
57V:V:L166 V:V:V20 16.03242.98YesYes1286
58V:V:L166 V:V:R25 13.13483.64YesYes089
59V:V:V20 V:V:V41 28.84343.21YesNo065
60V:V:S86 V:V:V41 28.2023.23NoNo065
61V:V:S86 V:V:Y113 26.91512.54NoYes063
62V:V:V43 V:V:Y113 14.39515.05NoYes363
63V:V:L18 V:V:V43 13.97594.47NoNo066
64V:V:L18 V:V:S13 13.29043NoNo068
65V:V:N15 V:V:S13 10.51197.45YesNo088
66V:V:L293 V:V:R25 12.7924.86YesYes089
67V:V:Q237 V:V:V319 20.62854.3YesNo698
68V:V:L287 V:V:Q237 15.20675.32YesYes079
69V:V:L287 V:V:Q130 14.28156.65YesYes079
70V:V:L289 V:V:Q130 13.44047.99YesYes099
71V:V:K292 V:V:L289 12.12614.23YesYes2469
72V:V:H210 V:V:L351 19.16986.43NoNo098
73V:V:H210 V:V:H353 17.457421.5NoYes098
74V:V:H353 V:V:Y173 17.8312.18YesYes084
75V:V:I119 V:V:V34 15.44867.68YesNo057
76V:V:D29 V:V:V34 15.63435.84NoNo097
77V:V:D29 V:V:Q172 22.75866.53NoYes099
78V:V:L305 V:V:Q172 21.7643.99NoYes059
79V:V:P88 V:V:Y113 11.700712.52YesYes393
80V:V:F87 V:V:P88 10.56592.89YesYes349
81V:V:L305 V:V:M352 20.21494.24NoNo058
82V:V:M352 V:V:T350 17.87873.01NoNo084
83V:V:E206 V:V:T350 14.92225.64NoNo074
84V:V:E206 V:V:P182 14.22193.14NoYes079
85V:V:Q237 V:V:V253 21.30774.3YesNo099
86V:V:V235 V:V:V253 18.99463.21YesNo089
87V:V:L274 V:V:V235 35.69855.96NoYes058
88V:V:I233 V:V:L274 54.19754.28YesNo055
89V:V:I233 V:V:Y272 51.62796.04YesYes854
90V:V:I231 V:V:Y272 28.92542.42NoYes864
91V:V:I231 V:V:L327 28.1067.14NoYes067
92V:V:L327 V:V:V228 11.91172.98YesNo078
93V:V:N222 V:V:V228 21.45634.43NoNo098
94V:V:N222 V:V:T224 17.89418.77NoNo099
95V:V:K195 V:V:T224 16.11091.5NoNo079
96V:V:K195 V:V:P196 12.54041.67NoNo076
97V:V:P196 V:V:T187 10.7531.75NoNo065
98V:V:F349 V:V:V235 18.09182.62YesYes678
99V:V:F349 V:V:I214 18.26985.02YesYes678
100V:V:I214 V:V:L274 19.35284.28YesNo085
101V:V:F268 V:V:Y272 18.52712.06YesYes854
102V:V:F268 V:V:V262 17.78975.24YesNo057
103V:V:V228 V:V:V262 12.14868.02NoNo087
104V:V:L199 V:V:L327 15.56144.15YesYes067
105V:V:L199 V:V:V343 11.93622.98YesNo067
106V:V:R188 V:V:V343 11.02649.15NoNo087
107V:V:K324 V:V:R236 11.57736.19YesYes465
108V:V:F117 V:V:V37 11.4146.55YesNo088
109V:V:F349 V:V:L351 13.64163.65YesNo678
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 8JRU
Class B1
SubFamily Peptide
Type Glucagon
SubType Glucagon
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners Arrestin2
PDB Resolution 3.5
Date 2023-08-16
D.O.I. 10.1038/s41586-023-06420-x
Net Summary
Imin 1.77
Number of Linked Nodes 568
Number of Links 677
Number of Hubs 99
Number of Links mediated by Hubs 363
Number of Communities 27
Number of Nodes involved in Communities 172
Number of Links involved in Communities 222
Path Summary
Number Of Nodes in MetaPath 110
Number Of Links MetaPath 109
Number of Shortest Paths 289257
Length Of Smallest Path 3
Average Path Length 23.7214
Length of Longest Path 54
Minimum Path Strength 1.31
Average Path Strength 5.40753
Maximum Path Strength 22.91
Minimum Path Correlation 0.7
Average Path Correlation 0.967534
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.77778
Average % Of Corr. Nodes 51.5116
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 44.3599
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier
SCOP2Family Identifier
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodePIO
PDB ResiduesV:V:?701
Environment DetailsOpen EMBL-EBI Page
CodePIO
Name[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Synonymsdioctanoyl l-alpha-phosphatidyl-d-myo-inositol 4,5-diphosphate
Identifier[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
FormulaC25 H49 O19 P3
Molecular Weight746.566
SMILESCCCCCCCC(=O)OC[C@H](COP(=O)(O)O[C@@H]1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)OP(=O)(O)O)OP(=O)(O)O)O)O)OC(=O)CCCCCCC
PubChem9543520
Formal Charge0
Total Atoms96
Total Chiral Atoms7
Total Bonds96
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP47871
Sequence
>8JRU_Chain_R
SSFQVMYTV GYSLSLGAL LLALAILGG LSKLHCTRN AIHANLFAS 
FVLKASSVL VIDGLLRTR AVAGCRVAA VFMQYGIVA NYCWLLVEG 
LYLHNLLGE RSFFSLYLG IGWGAPMLF VVPWAVVKC LFENVQCWT 
SNDNMGFWW ILRFPVFLA ILINFFIFV RIVQLLVAK LRARQMHHT 
DYKFRLAKS TLTLIPLLG VHEVVFAFA KLFFDLFLS SFQGLLVAV 
LYCFLNKEV QSELRRRWH RWRLGKVLW EER


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainV
ProteinArrestin
UniProtP49407
Sequence
>8JRU_Chain_V
TRVFKKASP NGKLTVYLG KRDFVDHID LVEPVDGVV LVDPEYLKE 
RRVYVTLTA AFRYGTFRK DLFVANVQS FPPAPKKPL TRLQERLIK 
KLGEHAYPF TFEIPPNLP SSVTLQPGP EDTGKAIGV DYEVKAFVA 
ENLEEKIHK RNSVRLVIE KVQYAPERP GPQPTAETT RQFLMSDKP 
LHLEASLDK EIYYHGEPI SVNVHVTNN TNKTVKKIK ISVRQYADI 
VLFNTAQYK VPVAMEEAD DTVAPSSTF SKVYTLTPF LANNREKRG 
LALDGKLKH EDTNLASST LLREGANRE ILGIIVSYK VKVKLVVSR 
GASSDVAVE LPFTLMHPK PKEEPPHRE VPEH


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7CZ5B1PeptideGlucagonGHRHHomo sapiensSomatoliberin-Gs/&β;1/&γ;22.62020-11-1810.1038/s41467-020-18945-0
7V9LB1PeptideGlucagonGHRH (SV1)Homo sapiens--chim(NtGi1-Gs)/&β;1/&γ;22.62022-04-0610.1073/pnas.2106606118
7V9MB1PeptideGlucagonGHRH (SV1)Homo sapiensSomatoliberin-Gs/&β;1/&γ;23.292021-10-2010.1073/pnas.2106606118
7DTYB1PeptideGlucagonGIPHomo sapiensGIP-Gs/&β;1/&γ;22.982021-08-0410.7554/eLife.68719
7FINB1PeptideGlucagonGIPHomo sapiensPeptide-20; GGL-Gs/&β;1/&γ;23.12022-02-2310.1038/s41467-022-28683-0
7FIYB1PeptideGlucagonGIPHomo sapiensTirzepatide-Gs/&β;1/&γ;23.42022-03-0210.1038/s41467-022-28683-0
7RA3B1PeptideGlucagonGIPHomo sapiensGIP-chim(NtGi1-Gs)/&β;1/&γ;23.242022-04-1310.1073/pnas.2116506119
7RBTB1PeptideGlucagonGIPHomo sapiensTirzepatidePubChem 163183774chim(NtGi1-Gs)/&β;1/&γ;23.082022-04-1310.1073/pnas.2116506119
7VABB1PeptideGlucagonGIPHomo sapiensNon-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;23.22022-03-0210.1038/s41467-022-28683-0
8ITLB1PeptideGlucagonGIPHomo sapiens--Gs/&β;1/&γ;23.232023-10-1810.1073/pnas.2306145120
8ITMB1PeptideGlucagonGIPHomo sapiens--Gs/&β;1/&γ;23.132023-10-1810.1073/pnas.2306145120
8WA3B1PeptideGlucagonGIPHomo sapiens--Gs/&β;1/&γ;22.862024-03-0610.1038/s41421-024-00649-0
5NX2B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)--3.72017-06-1410.1038/nature22800
5VAIB1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-Gs/&β;1/&γ;24.12017-05-2410.1038/nature22394
5VEWB1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.72017-05-2410.1038/nature22378
5VEXB1PeptideGlucagonGLP-1Homo sapiens-NNC0640-32017-05-1710.1038/nature22378
6B3JB1PeptideGlucagonGLP-1Homo sapiensExendin-P5-Gs/&β;1/&γ;23.32018-02-2110.1038/nature25773
6KJVB1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-2.82019-11-1310.1107/S2052252519013496
6KK1B1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-2.82019-11-1310.1107/S2052252519013496
6KK7B1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-3.12019-11-1310.1107/S2052252519013496
6LN2B1PeptideGlucagonGLP-1Homo sapiens-PubChem 68178630-3.22020-03-1810.1038/s41467-020-14934-5
6ORVB1PeptideGlucagonGLP-1Homo sapiens-TT-OAD2Gs/&β;1/&γ;232020-01-0810.1038/s41586-019-1902-z
6VCBB1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN3160440Gs/&β;1/&γ;23.32020-07-2210.1038/s41589-020-0589-7
6X18B1PeptideGlucagonGLP-1Homo sapiensGLP-1-Gs/&β;1/&γ;22.12020-09-0910.1016/j.molcel.2020.09.020
6X19B1PeptideGlucagonGLP-1Homo sapiensCHU-128-Gs/&β;1/&γ;22.12020-09-0910.1016/j.molcel.2020.09.020
6X1AB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/&β;1/&γ;22.52020-09-0910.1016/j.molcel.2020.09.020
6XOXB1PeptideGlucagonGLP-1Homo sapiensOrforglipron-chim(NtGi1-Gs)/&β;1/&γ;23.12020-11-1810.1073/pnas.2014879117
7C2EB1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-Gs/&β;1/&γ;24.22020-08-2610.1038/s41422-020-0384-8
7DUQB1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 156022738Gs/&β;1/&γ;22.52021-07-1410.1038/s41467-021-24058-z
7DURB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/&β;1/&γ;23.32021-08-1110.1038/s41467-021-24058-z
7E14B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 156022738Gs/&β;1/&γ;22.92021-07-0710.1038/s41467-021-24058-z
7EVMB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/&β;1/&γ;22.52021-08-1110.1038/s41467-021-24058-z
7FIMB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-Gs/&β;1/&γ;23.42022-03-0210.1038/s41467-022-28683-0
7KI0B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-Gs/&β;1/&γ;22.52021-08-0410.1016/j.celrep.2021.109374
7KI1B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-Gs/&β;1/&γ;22.52021-08-0410.1016/j.celrep.2021.109374
7LCIB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/&β;1/&γ;22.92021-01-2010.1016/j.str.2021.04.008
7LCJB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--2.822021-01-2010.1016/j.str.2021.04.008
7LCKB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--3.242021-01-2010.1016/j.str.2021.04.008
7LLLB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/&β;1/&γ;23.72022-01-1210.1038/s41467-021-27760-0
7LLYB1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-Gs/&β;1/&γ;23.32022-01-1210.1038/s41467-021-27760-0
7RG9B1PeptideGlucagonGLP-1Homo sapiens--chim(NtGi1-Gs)/&β;1/&γ;23.22022-04-1310.1073/pnas.2116506119
7RGPB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-chim(NtGi1-Gs)/&β;1/&γ;22.92022-04-1310.1073/pnas.2116506119
7RTBB1PeptideGlucagonGLP-1Homo sapiensPeptide-19-Gs/&β;1/&γ;22.142021-10-0610.1016/j.bbrc.2021.09.016
7S15B1PeptideGlucagonGLP-1Homo sapiensPubChem 134611223--3.82022-06-0810.1021/acs.jmedchem.1c01856
7S1MB1PeptideGlucagonGLP-1Homo sapiensEx4-D-Ala-Gs/&β;1/&γ;22.412022-01-0510.1038/s41589-021-00945-w
7S3IB1PeptideGlucagonGLP-1Homo sapiens--Gs/&β;1/&γ;22.512022-01-0510.1038/s41589-021-00945-w
7VBHB1PeptideGlucagonGLP-1Homo sapiensPeptide-20-Gs/&β;1/&γ;232022-04-0610.1038/s41467-022-28683-0
7VBIB1PeptideGlucagonGLP-1Homo sapiensNon-Acylated Tirzepatide-Gs/&β;1/&γ;232022-03-0210.1038/s41467-022-28683-0
7X8RB1PeptideGlucagonGLP-1Homo sapiensBOC5-Gs/&β;1/&γ;22.612022-06-2910.1073/pnas.2200155119
7X8SB1PeptideGlucagonGLP-1Homo sapiensWB4-24-Gs/&β;1/&γ;23.092022-06-2910.1073/pnas.2200155119
8JIPB1PeptideGlucagonGLP-1Homo sapiensMEDI0382-chim(NtGi1-Gs)/&β;1/&γ;22.852023-09-0610.1073/pnas.2303696120
8JIRB1PeptideGlucagonGLP-1Homo sapiensSAR425899-chim(NtGi1-Gs)/&β;1/&γ;22.572023-09-0610.1073/pnas.2303696120
8JISB1PeptideGlucagonGLP-1Homo sapiensPeptide-15-chim(NtGi1-Gs)/&β;1/&γ;22.462023-11-0810.1073/pnas.2303696120
8WG7B1PeptideGlucagonGLP-1Homo sapiens--Gs/&β;1/&γ;22.542024-03-0610.1038/s41421-024-00649-0
7D68B1PeptideGlucagonGLP-2Homo sapiensGLP-2-Gs/&β;1/&γ;232020-12-1610.1038/s41422-020-00442-0
4L6RB1PeptideGlucagonGlucagonHomo sapiens---3.32013-07-2410.1038/nature12393
5EE7B1PeptideGlucagonGlucagonHomo sapiens-MK0893-2.52016-04-2010.1038/nature17414
5XEZB1PeptideGlucagonGlucagonHomo sapiens-NNC0640-32017-05-2410.1038/nature22363
5XF1B1PeptideGlucagonGlucagonHomo sapiens-NNC0640-3.192017-05-2410.1038/nature22363
5YQZB1PeptideGlucagonGlucagonHomo sapiensGlucagon analogue--32018-01-1710.1038/nature25153
6LMKB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Gs/&β;1/&γ;23.72020-04-0110.1126/science.aaz5346
6LMLB1PeptideGlucagonGlucagonHomo sapiensGlucagon--3.92020-04-0110.1126/science.aaz5346
6WHCB1PeptideGlucagonGlucagonHomo sapiensGlu16 analog of GCG-Gs/&β;1/&γ;23.42020-05-2710.1074/jbc.RA120.013793
6WPWB1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-Gs/&β;1/&γ;23.12020-08-1210.1126/science.aba3373
7V35B1PeptideGlucagonGlucagonHomo sapiensPeptide-20-Gs/&β;1/&γ;23.52022-03-0210.1038/s41467-022-28683-0
8FU6B1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-Gs/&β;1/&γ;22.92023-04-1210.1016/j.cell.2023.02.028
8JIQB1PeptideGlucagonGlucagonHomo sapiensPeptide-15-Gs/&β;1/&γ;23.42023-09-1310.1073/pnas.2303696120
8JITB1PeptideGlucagonGlucagonHomo sapiensMEDI0382-Gs/&β;1/&γ;22.912023-09-0610.1073/pnas.2303696120
8JIUB1PeptideGlucagonGlucagonHomo sapiensSAR425899-Gs/&β;1/&γ;22.762023-09-1310.1073/pnas.2303696120
8JRUB1PeptideGlucagonGlucagonHomo sapiens--Arrestin23.52023-08-1610.1038/s41586-023-06420-x
8JRVB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Arrestin23.32023-08-1610.1038/s41586-023-06420-x
8WG8B1PeptideGlucagonGlucagonHomo sapiens-Peptidechim(NtGi1-Gs)/&β;1/&γ;22.712024-03-0610.1038/s41421-024-00649-0
6WI9B1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/&β;1/&γ;24.32020-08-1210.1038/s41467-020-17791-4
6WZGB1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/&β;1/&γ;22.32020-08-1210.1038/s41467-020-17791-4
7D3SB1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/&β;1/&γ;22.92020-11-0410.1016/j.bbrc.2020.08.042




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