psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D299	R:R:Q27	13.05	No	No	0	4	5
2	R:R:P86	R:R:V28	3.53	Yes	Yes	0	3	3
3	L:L:D15	R:R:V28	4.38	Yes	Yes	0	0	3
4	R:R:M29	R:R:W215	6.98	No	Yes	3	5	2
5	L:L:D15	R:R:M29	8.32	Yes	No	3	0	5
6	L:L:R18	R:R:M29	6.2	No	No	3	0	5
7	R:R:D30	R:R:L216	4.07	No	No	0	5	2
8	R:R:E34	R:R:F31	3.5	No	No	0	2	4
9	R:R:F31	R:R:K35	6.2	No	No	0	4	4
10	R:R:L32	R:R:Y84	4.69	No	Yes	0	4	5
11	R:R:L32	R:R:P86	3.28	No	Yes	0	4	3
12	L:L:F22	R:R:L32	3.65	Yes	No	0	0	4
13	R:R:F33	R:R:S213	5.28	No	No	0	4	3
14	R:R:F33	R:R:L216	4.87	No	No	0	4	2
15	L:L:F22	R:R:F33	5.36	Yes	No	0	0	4
16	R:R:K35	R:R:W83	6.96	No	No	0	4	2
17	R:R:K37	R:R:W36	3.48	No	Yes	0	3	6
18	R:R:W36	R:R:Y84	10.61	Yes	Yes	1	6	5
19	R:R:D209	R:R:W36	7.82	No	Yes	0	4	6
20	L:L:F22	R:R:W36	4.01	Yes	Yes	1	0	6
21	L:L:L26	R:R:W36	5.69	Yes	Yes	1	0	6
22	R:R:F62	R:R:Y39	6.19	No	Yes	1	7	6
23	R:R:C67	R:R:Y39	4.03	No	Yes	1	9	6
24	R:R:P82	R:R:Y39	5.56	No	Yes	1	8	6
25	R:R:W83	R:R:Y39	10.61	No	Yes	0	2	6
26	R:R:Y39	R:R:Y84	7.94	Yes	Yes	1	6	5
27	R:R:C43	R:R:Q42	4.58	No	No	1	9	5
28	R:R:N46	R:R:Q42	3.96	Yes	No	1	5	5
29	R:R:Q42	R:R:W83	3.29	No	No	0	5	2
30	R:R:C43	R:R:N46	4.72	No	Yes	1	9	5
31	R:R:C43	R:R:C67	7.28	No	No	1	9	9
32	R:R:H44	R:R:L47	5.14	No	No	0	2	5
33	R:R:H45	R:R:N46	6.38	No	Yes	1	4	5
34	R:R:H45	R:R:S48	4.18	No	No	0	4	3
35	R:R:H45	R:R:L49	3.86	No	No	1	4	2
36	R:R:L49	R:R:N46	6.87	No	Yes	1	2	5
37	R:R:L50	R:R:R60	9.72	No	No	0	3	4
38	R:R:P52	R:R:P53	3.9	No	No	0	1	3
39	R:R:P53	R:R:V57	7.07	No	No	0	3	3
40	R:R:E55	R:R:T54	8.47	No	No	0	4	1
41	R:R:E55	R:R:T71	9.88	No	No	0	4	7
42	R:R:G104	R:R:L56	5.13	No	No	0	9	2
43	R:R:R60	R:R:V57	3.92	No	No	0	4	3
44	R:R:C58	R:R:D70	6.22	Yes	Yes	2	9	4
45	R:R:C58	R:R:P72	3.77	Yes	Yes	2	9	1
46	R:R:C100	R:R:C58	7.28	No	Yes	2	9	9
47	R:R:C58	R:R:G104	3.92	Yes	No	0	9	9
48	R:R:C58	R:R:W106	6.53	Yes	Yes	2	9	9
49	R:R:N59	R:R:Q105	6.6	No	Yes	2	4	5
50	R:R:N59	R:R:W106	6.78	No	Yes	2	4	9
51	R:R:D70	R:R:R60	13.1	Yes	No	0	4	4
52	R:R:T61	R:R:W68	6.06	No	Yes	0	6	9
53	R:R:C67	R:R:F62	5.59	No	No	1	9	7
54	R:R:D63	R:R:Y65	11.49	Yes	Yes	2	9	6
55	R:R:D63	R:R:S66	5.89	Yes	No	2	9	5
56	R:R:D63	R:R:W68	10.05	Yes	Yes	2	9	9
57	R:R:D63	R:R:K98	5.53	Yes	No	2	9	8
58	R:R:S66	R:R:Y65	5.09	No	Yes	2	5	6
59	R:R:R116	R:R:Y65	15.43	No	Yes	2	6	6
60	L:L:M27	R:R:Y65	15.57	Yes	Yes	2	0	6
61	R:R:S66	R:R:W68	4.94	No	Yes	2	5	9
62	R:R:D70	R:R:W68	5.58	Yes	Yes	2	4	9
63	R:R:I79	R:R:W68	3.52	Yes	Yes	0	4	9
64	R:R:K98	R:R:W68	4.64	No	Yes	2	8	9
65	R:R:W106	R:R:W68	13.12	Yes	Yes	2	9	9
66	R:R:D70	R:R:P72	4.83	Yes	Yes	2	4	1
67	R:R:D70	R:R:W106	7.82	Yes	Yes	2	4	9
68	R:R:N74	R:R:R99	9.64	No	No	0	7	3
69	R:R:N74	R:R:P102	14.66	No	No	0	7	1
70	R:R:R99	R:R:T76	3.88	No	No	0	3	5
71	R:R:A77	R:R:I79	3.25	No	Yes	0	7	4
72	R:R:C81	R:R:V96	3.42	No	No	0	9	7
73	R:R:C121	R:R:C81	7.28	No	No	0	9	9
74	R:R:P82	R:R:Y84	5.56	No	Yes	1	8	5
75	R:R:L85	R:R:P82	4.93	Yes	No	1	6	8
76	R:R:L85	R:R:P86	4.93	Yes	Yes	1	6	3
77	R:R:L85	R:R:W87	7.97	Yes	No	1	6	3
78	R:R:P86	R:R:W87	12.16	Yes	No	1	3	3
79	R:R:M123	R:R:W87	6.98	Yes	No	0	3	3
80	R:R:H88	R:R:H89	11.94	No	No	0	4	5
81	R:R:D124	R:R:K90	6.91	No	No	6	2	4
82	R:R:E127	R:R:K90	6.75	No	No	6	1	4
83	R:R:R94	R:R:V91	5.23	No	No	0	5	6
84	R:R:C121	R:R:V91	3.42	No	No	0	9	6
85	R:R:H93	R:R:Q92	21.02	No	No	0	4	1
86	R:R:Q120	R:R:R94	11.68	No	No	0	5	5
87	R:R:D117	R:R:F97	13.14	No	No	0	7	5
88	R:R:K98	R:R:W106	11.6	No	Yes	2	8	9
89	R:R:C100	R:R:W106	5.22	No	Yes	2	9	9
90	R:R:G101	R:R:P102	4.06	No	No	0	5	1
91	R:R:D103	R:R:Q105	3.92	No	Yes	0	5	5
92	R:R:Q105	R:R:W106	3.29	Yes	Yes	2	5	9
93	R:R:Q105	R:R:R108	9.35	Yes	No	2	5	1
94	R:R:R108	R:R:W106	4	No	Yes	2	1	9
95	R:R:V107	R:R:W115	3.68	No	No	0	5	4
96	R:R:G109	R:R:P110	4.06	No	No	7	4	3
97	R:R:G109	R:R:Q113	6.58	No	Yes	7	4	4
98	R:R:P110	R:R:Q113	4.74	No	Yes	7	3	4
99	R:R:Q113	R:R:W115	3.29	Yes	No	0	4	4
100	R:R:A118	R:R:R116	8.3	No	No	0	5	6
101	L:L:M27	R:R:R116	12.41	Yes	No	2	0	6
102	R:R:C121	R:R:Q120	6.1	No	No	0	9	5
103	R:R:M123	R:R:Q122	5.44	Yes	No	0	3	3
104	R:R:I128	R:R:M123	5.83	No	Yes	0	2	3
105	L:L:Q20	R:R:M123	6.8	No	Yes	0	0	3
106	R:R:D124	R:R:E127	9.09	No	No	6	2	1
107	R:R:G125	R:R:I128	5.29	No	No	0	2	2
108	L:L:Y13	R:R:Q131	9.02	Yes	No	8	0	3
109	L:L:R17	R:R:Q131	7.01	No	No	8	0	3
110	L:L:Q20	R:R:Q131	10.24	No	No	0	0	3
111	R:R:M137	R:R:Y138	3.59	Yes	Yes	0	4	5
112	R:R:F141	R:R:M137	6.22	No	Yes	0	6	4
113	L:L:D9	R:R:Y138	4.6	No	Yes	0	0	5
114	L:L:Y10	R:R:Y138	6.95	No	Yes	0	0	5
115	L:L:Y13	R:R:Y138	3.97	Yes	Yes	0	0	5
116	R:R:F141	R:R:F383	8.57	No	No	0	6	5
117	L:L:F6	R:R:F141	5.36	No	No	0	0	6
118	R:R:D195	R:R:Q142	3.92	No	No	0	7	5
119	L:L:Y10	R:R:Q142	7.89	No	No	0	0	5
120	R:R:F383	R:R:M144	3.73	No	No	0	5	6
121	R:R:F387	R:R:M144	3.73	No	No	0	5	6
122	R:R:T146	R:R:Y145	6.24	No	Yes	0	7	7
123	R:R:Y145	R:R:Y149	7.94	Yes	Yes	5	7	8
124	R:R:V191	R:R:Y145	3.79	No	Yes	5	7	7
125	R:R:L386	R:R:Y145	3.52	No	Yes	0	7	7
126	L:L:F6	R:R:Y145	6.19	No	Yes	0	0	7
127	R:R:L192	R:R:T146	4.42	No	No	0	7	7
128	R:R:F391	R:R:G148	6.02	Yes	No	0	7	7
129	R:R:A188	R:R:Y149	5.34	No	Yes	0	8	8
130	R:R:V191	R:R:Y149	6.31	No	Yes	5	7	8
131	R:R:L192	R:R:Y149	3.52	No	Yes	0	7	8
132	L:L:Q3	R:R:Y149	5.64	No	Yes	5	0	8
133	R:R:F391	R:R:L151	4.87	Yes	No	9	7	5
134	R:R:L151	R:R:L394	4.15	No	No	9	5	5
135	R:R:F181	R:R:L156	6.09	Yes	Yes	0	8	8
136	R:R:F184	R:R:L156	4.87	Yes	Yes	0	8	8
137	R:R:A397	R:R:L156	4.73	No	Yes	0	8	8
138	R:R:A159	R:R:F181	4.16	No	Yes	10	9	8
139	R:R:A159	R:R:C401	3.61	No	Yes	10	9	9
140	R:R:A159	R:R:F402	4.16	No	No	0	9	9
141	R:R:F181	R:R:L160	7.31	Yes	No	0	8	6
142	R:R:C401	R:R:I162	3.27	Yes	No	0	9	8
143	R:R:C401	R:R:L163	4.76	Yes	No	0	9	8
144	R:R:E410	R:R:L166	6.63	Yes	No	0	8	7
145	R:R:L166	R:R:R414	7.29	No	No	0	7	5
146	R:R:C171	R:R:K168	3.23	No	No	0	7	8
147	R:R:E410	R:R:K168	5.4	Yes	No	0	8	8
148	R:R:H170	R:R:L169	6.43	No	No	0	7	9
149	R:R:C171	R:R:N174	6.3	No	No	0	7	9
150	R:R:F264	R:R:T172	3.89	No	No	0	6	7
151	R:R:N174	R:R:R173	4.82	No	No	0	9	9
152	R:R:R173	R:R:Y248	4.12	No	No	0	9	8
153	R:R:E245	R:R:I176	6.83	Yes	No	0	9	9
154	R:R:I176	R:R:Y248	3.63	No	No	0	9	8
155	R:R:E245	R:R:H177	14.77	Yes	No	0	9	9
156	R:R:H177	R:R:Y400	5.44	No	No	0	9	8
157	R:R:N179	R:R:W241	5.65	No	Yes	0	8	9
158	R:R:F184	R:R:L180	3.65	Yes	Yes	0	8	9
159	R:R:L180	R:R:W241	6.83	Yes	Yes	0	9	9
160	R:R:L180	R:R:L242	4.15	Yes	No	0	9	9
161	R:R:E245	R:R:L180	5.3	Yes	Yes	0	9	9
162	R:R:C401	R:R:F181	5.59	Yes	Yes	10	9	8
163	R:R:N238	R:R:S183	5.96	No	No	0	9	9
164	R:R:S183	R:R:W241	6.18	No	Yes	4	9	9
165	R:R:S183	R:R:W272	3.71	No	Yes	4	9	9
166	R:R:F184	R:R:N238	10.87	Yes	No	0	8	9
167	R:R:F184	R:R:Q392	8.2	Yes	No	0	8	9
168	R:R:F184	R:R:G393	6.02	Yes	No	0	8	9
169	R:R:L186	R:R:W272	3.42	No	Yes	0	7	9
170	R:R:I235	R:R:K187	5.82	No	No	0	5	8
171	R:R:K187	R:R:N238	11.19	No	No	0	8	9
172	R:R:K187	R:R:Y239	4.78	No	No	0	8	8
173	R:R:F230	R:R:S190	7.93	No	No	0	4	5
174	L:L:Q3	R:R:V191	5.73	No	No	5	0	7
175	R:R:I194	R:R:M231	5.83	No	Yes	0	6	6
176	R:R:D195	R:R:G196	5.03	No	No	0	7	3
177	R:R:D195	R:R:R199	3.57	No	No	0	7	4
178	R:R:R201	R:R:Y202	5.14	No	Yes	3	4	1
179	R:R:R201	R:R:W215	13.99	No	Yes	3	4	2
180	R:R:R201	R:R:V221	5.23	No	No	0	4	4
181	R:R:W215	R:R:Y202	4.82	Yes	Yes	3	2	1
182	R:R:Q293	R:R:Y202	4.51	Yes	Yes	3	4	1
183	L:L:L14	R:R:Y202	10.55	No	Yes	0	0	1
184	L:L:D15	R:R:Y202	3.45	Yes	Yes	3	0	1
185	L:L:R18	R:R:I206	7.52	No	No	0	0	4
186	L:L:W25	R:R:I206	5.87	Yes	No	0	0	4
187	L:L:W25	R:R:G207	4.22	Yes	No	0	0	1
188	R:R:D208	R:R:L210	4.07	No	No	0	4	4
189	L:L:W25	R:R:D209	8.93	Yes	No	0	0	4
190	R:R:S211	R:R:V212	3.23	No	No	0	4	3
191	R:R:D218	R:R:T214	4.34	No	No	0	4	1
192	R:R:L216	R:R:W215	4.56	No	Yes	0	2	2
193	L:L:R18	R:R:W215	14.99	No	Yes	3	0	2
194	R:R:D218	R:R:S217	8.83	No	No	0	4	4
195	R:R:R225	R:R:V221	6.54	No	No	0	8	4
196	R:R:C224	R:R:C294	7.28	No	No	0	9	9
197	R:R:N291	R:R:R225	14.46	No	No	11	6	8
198	R:R:R225	R:R:W295	10	No	Yes	11	8	9
199	R:R:V229	R:R:W282	4.9	No	Yes	0	6	9
200	R:R:M231	R:R:Q232	5.44	Yes	Yes	0	6	7
201	L:L:T7	R:R:M231	4.52	No	Yes	0	0	6
202	R:R:Q232	R:R:W282	6.57	Yes	Yes	12	7	9
203	R:R:L307	R:R:Q232	6.65	No	Yes	12	7	7
204	L:L:H1	R:R:Q232	4.95	Yes	Yes	0	0	7
205	R:R:A237	R:R:Y233	9.34	No	Yes	4	7	9
206	R:R:W272	R:R:Y233	4.82	Yes	Yes	4	9	9
207	R:R:P275	R:R:Y233	6.95	Yes	Yes	4	9	9
208	R:R:M276	R:R:Y233	5.99	No	Yes	0	3	9
209	R:R:V279	R:R:Y233	5.05	No	Yes	0	6	9
210	L:L:H1	R:R:I235	9.28	Yes	No	0	0	5
211	R:R:P275	R:R:V236	3.53	Yes	No	0	9	6
212	R:R:L307	R:R:V236	5.96	No	No	0	7	6
213	R:R:V236	R:R:V311	4.81	No	No	0	6	8
214	R:R:A237	R:R:P275	3.74	No	Yes	4	7	9
215	R:R:V311	R:R:Y239	8.83	No	No	0	8	8
216	R:R:H361	R:R:Y239	14.16	Yes	No	0	8	8
217	R:R:W241	R:R:W272	14.06	Yes	Yes	4	9	9
218	R:R:L243	R:R:L247	4.15	No	No	0	8	7
219	R:R:V244	R:R:Y267	7.57	No	No	0	8	7
220	R:R:E245	R:R:L357	3.98	Yes	Yes	0	9	9
221	R:R:G246	R:R:N318	5.09	No	No	0	9	9
222	R:R:G246	R:R:I321	3.53	No	No	0	9	8
223	R:R:H250	R:R:L247	3.86	No	No	0	7	7
224	R:R:L252	R:R:Y248	5.86	No	No	0	8	8
225	R:R:H250	R:R:L255	7.71	No	No	0	7	5
226	R:R:H250	R:R:I321	3.98	No	No	0	7	8
227	R:R:N251	R:R:P259	4.89	No	No	0	7	6
228	R:R:N251	R:R:S262	4.47	No	No	0	7	5
229	R:R:L253	R:R:L328	5.54	No	No	0	8	8
230	R:R:F278	R:R:P310	26.01	No	No	0	5	9
231	R:R:P281	R:R:V280	3.53	No	No	0	4	2
232	R:R:K286	R:R:W282	8.12	No	Yes	0	8	9
233	R:R:L307	R:R:W282	9.11	No	Yes	12	7	9
234	R:R:F303	R:R:V285	6.55	No	No	0	4	5
235	R:R:K286	R:R:W295	9.28	No	Yes	0	8	9
236	R:R:C287	R:R:W295	5.22	No	Yes	0	3	9
237	R:R:F289	R:R:L288	6.09	No	No	0	3	1
238	R:R:E290	R:R:F289	5.83	No	No	0	6	3
239	R:R:F289	R:R:F303	13.93	No	No	0	3	4
240	R:R:E290	R:R:V292	4.28	No	No	0	6	4
241	R:R:N291	R:R:W295	12.43	No	Yes	11	6	9
242	R:R:Q293	R:R:S297	4.33	Yes	No	0	4	4
243	L:L:D15	R:R:Q293	10.44	Yes	Yes	3	0	4
244	R:R:C294	R:R:T296	3.38	No	No	0	9	5
245	L:L:S11	R:R:T296	6.4	No	No	0	0	5
246	L:L:S11	R:R:S297	3.26	No	No	0	0	4
247	R:R:N298	R:R:W304	23.73	No	Yes	0	6	6
248	L:L:S8	R:R:N298	8.94	No	No	0	0	6
249	R:R:F303	R:R:N300	6.04	No	No	0	4	5
250	R:R:M301	R:R:W304	4.65	No	Yes	0	5	6
251	R:R:G302	R:R:W305	4.22	No	No	0	2	7
252	R:R:R308	R:R:W304	10	Yes	Yes	0	6	6
253	R:R:D370	R:R:W304	8.93	No	Yes	14	4	6
254	L:L:T5	R:R:W304	3.64	Yes	Yes	14	0	6
255	R:R:T369	R:R:W305	6.06	No	No	0	7	7
256	R:R:E371	R:R:W305	6.54	No	No	0	5	7
257	R:R:F365	R:R:R308	5.34	Yes	Yes	0	7	6
258	R:R:R308	R:R:T369	3.88	Yes	No	0	6	7
259	L:L:H1	R:R:R308	3.39	Yes	Yes	0	0	6
260	L:L:H1	R:R:V311	8.3	Yes	No	0	0	8
261	R:R:F312	R:R:M366	6.22	No	Yes	0	5	7
262	R:R:H361	R:R:I315	3.98	Yes	No	0	8	7
263	R:R:E362	R:R:I315	5.47	No	No	0	8	7
264	R:R:L358	R:R:N318	15.1	Yes	No	0	9	9
265	R:R:F319	R:R:V323	3.93	No	No	0	7	5
266	R:R:E362	R:R:F319	22.15	No	No	0	8	7
267	R:R:F322	R:R:V326	5.24	No	No	15	9	7
268	R:R:F322	R:R:L352	4.87	No	No	15	9	8
269	R:R:F322	R:R:I355	3.77	No	Yes	0	9	8
270	R:R:L352	R:R:V326	4.47	No	No	15	8	7
271	R:R:L329	R:R:T351	5.9	No	No	0	9	9
272	R:R:K332	R:R:R336	4.95	No	No	0	9	5
273	R:R:D342	R:R:H340	17.65	No	No	0	7	5
274	R:R:H340	R:R:Y343	6.53	No	No	0	5	7
275	R:R:R346	R:R:Y343	7.2	No	No	0	8	7
276	R:R:L347	R:R:Y343	3.52	No	No	0	9	7
277	R:R:L354	R:R:L399	6.92	No	No	0	9	8
278	R:R:I355	R:R:P356	3.39	Yes	No	0	8	9
279	R:R:L357	R:R:L358	8.3	Yes	Yes	0	9	9
280	R:R:L357	R:R:Y400	7.03	Yes	No	0	9	8
281	R:R:G359	R:R:L358	3.42	No	Yes	0	9	9
282	R:R:L388	R:R:V360	7.45	No	No	0	6	6
283	R:R:Q392	R:R:V360	4.3	No	No	0	9	6
284	R:R:F365	R:R:H361	9.05	Yes	Yes	13	7	8
285	R:R:D385	R:R:H361	10.08	No	Yes	13	7	8
286	R:R:H361	R:R:S389	4.18	Yes	No	0	8	6
287	R:R:E362	R:R:M366	4.06	No	Yes	0	8	7
288	R:R:K381	R:R:V364	4.55	Yes	No	0	7	6
289	R:R:F365	R:R:M366	7.46	Yes	Yes	0	7	7
290	R:R:D385	R:R:F365	3.58	No	Yes	13	7	7
291	R:R:K381	R:R:V368	7.59	Yes	No	0	7	5
292	R:R:D370	R:R:R378	7.15	No	No	0	4	4
293	L:L:T5	R:R:D370	14.45	Yes	No	14	0	4
294	R:R:E371	R:R:H372	6.15	No	No	0	5	4
295	R:R:S379	R:R:T376	4.8	No	No	0	3	2
296	L:L:D9	R:R:R378	5.96	No	No	0	0	4
297	L:L:T5	R:R:L382	5.9	Yes	No	0	0	5
298	R:R:F384	R:R:L388	14.61	No	No	0	4	6
299	L:L:S2	R:R:D385	5.89	No	No	0	0	7
300	L:L:Q3	R:R:L386	5.32	No	No	0	0	7
301	R:R:F387	R:R:F391	5.36	No	Yes	0	5	7
302	R:R:F391	R:R:L394	3.65	Yes	No	9	7	5
303	R:R:F402	R:R:V398	5.24	No	No	0	9	6
304	R:R:N404	R:R:V407	7.39	No	No	0	9	9
305	R:R:K405	R:R:Q408	8.14	No	No	0	6	7
306	R:R:E410	R:R:R413	10.47	Yes	No	0	8	7
307	L:L:G4	L:L:H1	4.77	No	Yes	0	0	0
308	L:L:D9	L:L:T5	4.34	No	Yes	0	0	0
309	L:L:L14	L:L:Y10	3.52	No	No	0	0	0
310	L:L:L14	L:L:Y13	3.52	No	Yes	0	0	0
311	L:L:R17	L:L:Y13	8.23	No	Yes	8	0	0
312	L:L:D21	L:L:R17	4.76	No	No	0	0	0
313	L:L:F22	L:L:L26	3.65	Yes	Yes	1	0	0
314	L:L:L26	L:L:W25	4.56	Yes	Yes	0	0	0
315	L:L:T29	L:L:W25	3.64	No	Yes	0	0	0
316	R:R:D63	R:R:P114	3.22	Yes	No	0	9	5
317	R:R:F95	R:R:F97	3.22	No	No	0	1	5
318	R:R:V363	R:R:V364	3.21	No	No	0	6	6
319	R:R:A373	R:R:K381	3.21	No	Yes	0	3	7
320	R:R:R413	R:R:R417	3.2	No	No	0	7	7
321	R:R:R414	R:R:R417	3.2	No	No	0	5	7
322	R:R:A188	R:R:L153	3.15	No	No	0	8	6
323	R:R:A178	R:R:L163	3.15	No	No	0	7	8
324	R:R:A314	R:R:L243	3.15	No	No	0	8	8
325	R:R:F264	R:R:Y267	3.09	No	No	0	6	7
326	R:R:I79	R:R:V96	3.07	Yes	No	0	4	7
327	R:R:M137	R:R:S379	3.07	Yes	No	0	4	3
328	R:R:I176	R:R:V244	3.07	No	No	0	9	8
329	R:R:I206	R:R:V212	3.07	No	No	0	4	3
330	R:R:I306	R:R:V285	3.07	No	No	0	8	5
331	R:R:I355	R:R:T351	3.04	Yes	No	0	8	9
332	L:L:M27	L:L:V23	3.04	Yes	No	0	0	0
333	R:R:L156	R:R:S152	3	Yes	No	0	8	9
334	L:L:V23	R:R:L85	2.98	No	Yes	0	0	6
335	R:R:L153	R:R:V185	2.98	No	No	0	6	8
336	R:R:L156	R:R:V185	2.98	Yes	No	0	8	8
337	R:R:L157	R:R:V185	2.98	No	No	0	3	8
338	R:R:L357	R:R:V396	2.98	Yes	No	0	9	9
339	R:R:D208	R:R:S211	2.94	No	No	0	4	4
340	R:R:I325	R:R:I355	2.94	No	Yes	0	9	8
341	R:R:G234	R:R:Y233	2.9	No	Yes	0	5	9
342	R:R:F309	R:R:P310	2.89	No	No	0	4	9
343	R:R:D342	R:R:T341	2.89	No	No	0	7	6
344	R:R:Q293	R:R:V292	2.87	Yes	No	0	4	4
345	R:R:E133	R:R:V130	2.85	No	No	0	2	1
346	R:R:I317	R:R:L243	2.85	No	No	0	6	8
347	R:R:I325	R:R:L249	2.85	No	No	0	9	9
348	R:R:I325	R:R:L253	2.85	No	No	0	9	8
349	R:R:I317	R:R:L313	2.85	No	No	0	6	3
350	R:R:I355	R:R:L358	2.85	Yes	Yes	0	8	9
351	R:R:K349	R:R:L352	2.82	No	No	0	9	8
352	R:R:K381	R:R:L382	2.82	Yes	No	0	7	5
353	R:R:G271	R:R:W241	2.81	No	Yes	0	9	9
354	L:L:M27	L:L:N28	2.8	Yes	No	0	0	0
355	R:R:L47	R:R:L50	2.77	No	No	0	5	3
356	R:R:L166	R:R:L411	2.77	No	No	0	7	5
357	L:L:K12	R:R:D299	2.77	No	No	0	0	4
358	L:L:Y13	R:R:A135	2.67	Yes	No	0	0	3
359	R:R:F95	R:R:S80	2.64	No	No	0	1	3
360	R:R:F391	R:R:S390	2.64	Yes	No	0	7	9
361	L:L:N28	L:L:Q24	2.64	No	No	0	0	0
362	R:R:D117	R:R:Q120	2.61	No	No	0	7	5
363	R:R:E406	R:R:E410	2.54	No	Yes	0	9	8
364	R:R:H89	R:R:Q92	2.47	No	No	0	5	1
365	R:R:F402	R:R:L158	2.44	No	No	0	9	5
366	R:R:L333	R:R:R334	2.43	No	No	0	7	7
367	R:R:F95	R:R:N78	2.42	No	No	0	1	4
368	R:R:D124	R:R:R126	2.38	No	No	0	2	3
369	R:R:L198	R:R:Y202	2.34	No	Yes	0	6	1
370	R:R:L399	R:R:Y400	2.34	No	No	0	8	8
371	R:R:E129	R:R:R126	2.33	No	No	0	1	3
372	R:R:Q204	R:R:W215	2.19	No	Yes	0	4	2
373	R:R:G164	R:R:G165	2.11	No	No	0	3	3
374	R:R:G273	R:R:P275	2.03	No	Yes	0	6	9
375	R:R:R419	R:R:W415	2	No	No	0	5	5
376	R:R:C100	R:R:G101	1.96	No	No	0	9	5
377	R:R:P51	R:R:P52	1.95	No	No	0	2	1
378	R:R:C240	R:R:P275	1.88	No	Yes	0	6	9
379	R:R:C240	R:R:P310	1.88	No	No	0	6	9
380	R:R:A274	R:R:P275	1.87	No	Yes	0	4	9
381	R:R:G148	R:R:V147	1.84	No	No	0	7	5
382	R:R:G219	R:R:V221	1.84	No	No	0	3	4
383	R:R:G223	R:R:V226	1.84	No	No	0	3	4
384	R:R:G271	R:R:I270	1.76	No	No	0	9	7
385	R:R:P72	R:R:T71	1.75	Yes	No	0	1	7
386	R:R:P72	R:R:T75	1.75	Yes	No	0	1	5
387	R:R:G223	R:R:L197	1.71	No	No	0	3	4
388	R:R:G254	R:R:L258	1.71	No	No	0	6	6
389	R:R:A380	R:R:S379	1.71	No	No	0	4	3
390	L:L:A19	R:R:V28	1.7	No	Yes	0	0	3
391	R:R:A227	R:R:V193	1.7	No	No	0	6	5
392	R:R:I79	R:R:P69	1.69	Yes	No	0	4	6
393	R:R:A73	R:R:T75	1.68	No	No	0	6	5
394	R:R:A228	R:R:T296	1.68	No	No	0	5	5
395	R:R:G112	R:R:Q113	1.64	No	Yes	0	6	4
396	R:R:L258	R:R:P259	1.64	No	No	0	6	6
397	R:R:G375	R:R:Q374	1.64	No	No	0	2	4
398	R:R:S189	R:R:S190	1.63	No	No	0	4	5
399	L:L:S16	R:R:V28	1.62	No	Yes	0	0	3
400	R:R:A227	R:R:I194	1.62	No	No	0	6	6
401	R:R:C224	R:R:L197	1.59	No	No	0	9	4
402	R:R:P114	R:R:Q113	1.58	No	Yes	0	5	4
403	R:R:A155	R:R:L394	1.58	No	No	0	6	5
404	R:R:A182	R:R:L160	1.58	No	No	0	4	6
405	R:R:K136	R:R:S140	1.53	No	No	0	2	4
406	R:R:M231	R:R:S190	1.53	Yes	No	0	6	5
407	R:R:M137	R:R:V134	1.52	Yes	No	0	4	2
408	R:R:L169	R:R:S167	1.5	No	No	0	9	8
409	R:R:L266	R:R:S262	1.5	No	No	0	3	5
410	R:R:L377	R:R:V368	1.49	No	No	0	3	5
411	R:R:Q27	R:R:V292	1.43	No	No	0	5	4
412	R:R:E127	R:R:V130	1.43	No	No	0	1	1
413	R:R:E133	R:R:V134	1.43	No	No	0	2	2
414	R:R:K35	R:R:L38	1.41	No	No	0	4	3
415	L:L:L26	R:R:K64	1.41	Yes	No	0	0	4
416	R:R:K344	R:R:L333	1.41	No	No	0	6	7
417	R:R:L399	R:R:L403	1.38	No	No	0	8	5
418	R:R:L268	R:R:N179	1.37	No	No	0	5	8
419	R:R:D41	R:R:L38	1.36	No	No	0	4	3
420	R:R:R346	R:R:S350	1.32	No	No	0	8	9
421	R:R:H89	R:R:K90	1.31	No	No	0	5	4
422	R:R:F320	R:R:V323	1.31	No	No	0	5	5
423	R:R:E406	R:R:N404	1.31	No	No	0	9	9
424	R:R:A283	R:R:W282	1.3	No	Yes	0	5	9
425	R:R:S262	R:R:Y267	1.27	No	No	0	5	7
426	R:R:K332	R:R:R334	1.24	No	No	0	9	7
427	R:R:F367	R:R:M366	1.24	No	Yes	0	5	7
428	R:R:H372	R:R:Q374	1.24	No	No	0	4	4
429	R:R:L255	R:R:R324	1.21	No	No	0	5	8
430	R:R:Q113	R:R:R111	1.17	Yes	No	0	4	4
431	R:R:H416	R:R:R419	1.13	No	No	0	3	5
432	R:R:F263	R:R:R261	1.07	No	No	0	5	5
433	R:R:R412	R:R:W415	1	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:V28	2.8075	4	0	3
2	R:R:W36	6.322	5	1	6
3	R:R:Y39	6.866	5	1	6
4	R:R:N46	5.4825	4	1	5
5	R:R:C58	5.544	5	2	9
6	R:R:D63	7.236	5	2	9
7	R:R:Y65	11.895	4	2	6
8	R:R:W68	6.84429	7	2	9
9	R:R:D70	7.51	5	2	4
10	R:R:P72	3.025	4	2	1
11	R:R:I79	2.8825	4	0	4
12	R:R:Y84	7.2	4	1	5
13	R:R:L85	5.2025	4	1	6
14	R:R:P86	5.975	4	1	3
15	R:R:Q105	5.79	4	2	5
16	R:R:W106	7.295	8	2	9
17	R:R:Q113	3.16667	6	7	4
18	R:R:M123	6.2625	4	0	3
19	R:R:M137	3.6	4	0	4
20	R:R:Y138	4.7775	4	0	5
21	R:R:Y145	5.536	5	5	7
22	R:R:Y149	5.75	5	5	8
23	R:R:L156	4.334	5	0	8
24	R:R:L180	4.9825	4	0	9
25	R:R:F181	5.7875	4	10	8
26	R:R:F184	6.722	5	0	8
27	R:R:Y202	5.135	6	3	1
28	R:R:W215	7.92167	6	3	2
29	R:R:M231	4.33	4	0	6
30	R:R:Q232	5.9025	4	12	7
31	R:R:Y233	5.84167	6	4	9
32	R:R:W241	7.106	5	4	9
33	R:R:E245	7.72	4	0	9
34	R:R:W272	6.5025	4	4	9
35	R:R:P275	3.33333	6	4	9
36	R:R:W282	6	5	12	9
37	R:R:Q293	5.5375	4	3	4
38	R:R:W295	9.2325	4	11	9
39	R:R:W304	10.19	5	14	6
40	R:R:R308	5.6525	4	0	6
41	R:R:I355	3.198	5	0	8
42	R:R:L357	5.5725	4	0	9
43	R:R:L358	7.4175	4	0	9
44	R:R:H361	8.29	5	13	8
45	R:R:F365	6.3575	4	13	7
46	R:R:M366	4.745	4	0	7
47	R:R:K381	4.5425	4	0	7
48	R:R:F391	4.508	5	9	7
49	R:R:C401	4.3075	4	10	9
50	R:R:E410	6.26	4	0	8
51	L:L:H1	6.138	5	0	0
52	L:L:T5	7.0825	4	14	0
53	L:L:Y13	5.482	5	8	0
54	L:L:D15	6.6475	4	3	0
55	L:L:F22	4.1675	4	1	0
56	L:L:W25	5.444	5	0	0
57	L:L:L26	3.8275	4	1	0
58	L:L:M27	8.455	4	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:Q293	R:R:V292	19.8392	2.87	Yes	No	0	4	4
2	L:L:D15	R:R:V28	40.1103	4.38	Yes	Yes	0	0	3
3	R:R:P86	R:R:V28	37.3874	3.53	Yes	Yes	0	3	3
4	R:R:Q293	R:R:Y202	27.6471	4.51	Yes	Yes	3	4	1
5	R:R:W215	R:R:Y202	12.8952	4.82	Yes	Yes	3	2	1
6	L:L:R18	R:R:W215	11.8267	14.99	No	Yes	3	0	2
7	R:R:L216	R:R:W215	14.0097	4.56	No	Yes	0	2	2
8	R:R:L32	R:R:P86	12.4426	3.28	No	Yes	0	4	3
9	R:R:W83	R:R:Y39	15.0919	10.61	No	Yes	0	2	6
10	R:R:L85	R:R:P86	34.205	4.93	Yes	Yes	1	6	3
11	R:R:L85	R:R:P82	25.3056	4.93	Yes	No	1	6	8
12	R:R:P82	R:R:Y39	17.3208	5.56	No	Yes	1	8	6
13	L:L:F22	R:R:F33	11.744	5.36	Yes	No	0	0	4
14	R:R:F33	R:R:L216	12.8424	4.87	No	No	0	4	2
15	R:R:W36	R:R:Y84	10.2206	10.61	Yes	Yes	1	6	5
16	L:L:W25	R:R:I206	11.5786	5.87	Yes	No	0	0	4
17	L:L:R18	R:R:I206	13.187	7.52	No	No	0	0	4
18	L:L:V23	R:R:L85	100	2.98	No	Yes	0	0	6
19	L:L:M27	L:L:V23	99.5381	3.04	Yes	No	0	0	0
20	L:L:M27	R:R:Y65	96.551	15.57	Yes	Yes	2	0	6
21	R:R:D63	R:R:Y65	57.3414	11.49	Yes	Yes	2	9	6
22	R:R:D63	R:R:W68	39.5037	10.05	Yes	Yes	2	9	9
23	R:R:D70	R:R:W68	29.4393	5.58	Yes	Yes	2	4	9
24	R:R:D70	R:R:R60	13.6006	13.1	Yes	No	0	4	4
25	R:R:S66	R:R:Y65	39.2808	5.09	No	Yes	2	5	6
26	R:R:S66	R:R:W68	38.6098	4.94	No	Yes	2	5	9
27	R:R:D70	R:R:P72	10.0207	4.83	Yes	Yes	2	4	1
28	R:R:W106	R:R:W68	22.8585	13.12	Yes	Yes	2	9	9
29	R:R:D63	R:R:K98	12.0841	5.53	Yes	No	2	9	8
30	R:R:K98	R:R:W106	11.3695	11.6	No	Yes	2	8	9
31	R:R:C100	R:R:W106	14.846	5.22	No	Yes	2	9	9
32	R:R:I79	R:R:W68	25.1241	3.52	Yes	Yes	0	4	9
33	R:R:C100	R:R:G101	12.5896	1.96	No	No	0	9	5
34	R:R:G101	R:R:P102	10.0804	4.06	No	No	0	5	1
35	R:R:C81	R:R:V96	18.5248	3.42	No	No	0	9	7
36	R:R:I79	R:R:V96	20.1815	3.07	Yes	No	0	4	7
37	R:R:C121	R:R:C81	16.8635	7.28	No	No	0	9	9
38	R:R:M123	R:R:W87	68.5478	6.98	Yes	No	0	3	3
39	L:L:L14	R:R:Y202	40.9122	10.55	No	Yes	0	0	1
40	L:L:L14	L:L:Y10	21.6406	3.52	No	No	0	0	0
41	L:L:Y10	R:R:Y138	21.3074	6.95	No	Yes	0	0	5
42	R:R:M137	R:R:Y138	43.8649	3.59	Yes	Yes	0	4	5
43	R:R:M137	R:R:V134	13.8396	1.52	Yes	No	0	4	2
44	R:R:E133	R:R:V134	12.7114	1.43	No	No	0	2	2
45	R:R:E133	R:R:V130	11.5786	2.85	No	No	0	2	1
46	R:R:E127	R:R:V130	10.4412	1.43	No	No	0	1	1
47	L:L:L14	L:L:Y13	19.8989	3.52	No	Yes	0	0	0
48	L:L:Y13	R:R:Y138	87.8516	3.97	Yes	Yes	0	0	5
49	R:R:C121	R:R:Q120	11.8336	6.1	No	No	0	9	5
50	L:L:Q20	R:R:Q131	68.8649	10.24	No	No	0	0	3
51	L:L:Y13	R:R:Q131	68.318	9.02	Yes	No	8	0	3
52	R:R:F141	R:R:M137	34.0855	6.22	No	Yes	0	6	4
53	L:L:D9	R:R:Y138	76.6636	4.6	No	Yes	0	0	5
54	R:R:F141	R:R:F383	11.4637	8.57	No	No	0	6	5
55	L:L:F6	R:R:F141	27.1094	5.36	No	No	0	0	6
56	R:R:F383	R:R:M144	10.3378	3.73	No	No	0	5	6
57	L:L:F6	R:R:Y145	26.4867	6.19	No	Yes	0	0	7
58	R:R:Y145	R:R:Y149	21.4637	7.94	Yes	Yes	5	7	8
59	R:R:A188	R:R:Y149	21.0662	5.34	No	Yes	0	8	8
60	R:R:A188	R:R:L153	20.6572	3.15	No	No	0	8	6
61	R:R:L153	R:R:V185	20.2757	2.98	No	No	0	6	8
62	R:R:L156	R:R:V185	19.614	2.98	Yes	No	0	8	8
63	R:R:F181	R:R:L156	13.2031	6.09	Yes	Yes	0	8	8
64	R:R:R201	R:R:Y202	31.4522	5.14	No	Yes	3	4	1
65	R:R:R201	R:R:V221	46.9669	5.23	No	No	0	4	4
66	R:R:R225	R:R:V221	46.1903	6.54	No	No	0	8	4
67	R:R:R225	R:R:W295	44.9908	10	No	Yes	11	8	9
68	R:R:K286	R:R:W295	44.9494	9.28	No	Yes	0	8	9
69	R:R:K286	R:R:W282	44.761	8.12	No	Yes	0	8	9
70	R:R:Q232	R:R:W282	20.6342	6.57	Yes	Yes	12	7	9
71	L:L:H1	R:R:Q232	19.2004	4.95	Yes	Yes	0	0	7
72	L:L:H1	R:R:I235	63.6926	9.28	Yes	No	0	0	5
73	R:R:I235	R:R:K187	63.079	5.82	No	No	0	5	8
74	R:R:K187	R:R:N238	66.1834	11.19	No	No	0	8	9
75	R:R:F184	R:R:N238	62.8722	10.87	Yes	No	0	8	9
76	L:L:D9	L:L:T5	74.7518	4.34	No	Yes	0	0	0
77	L:L:T5	R:R:W304	70.8111	3.64	Yes	Yes	14	0	6
78	R:R:R308	R:R:W304	69.8966	10	Yes	Yes	0	6	6
79	L:L:H1	R:R:R308	56.4384	3.39	Yes	Yes	0	0	6
80	R:R:F184	R:R:L180	63.7753	3.65	Yes	Yes	0	8	9
81	R:R:E245	R:R:L180	73.3571	5.3	Yes	Yes	0	9	9
82	R:R:E245	R:R:I176	32.4839	6.83	Yes	No	0	9	9
83	R:R:I176	R:R:Y248	19.1131	3.63	No	No	0	9	8
84	R:R:R173	R:R:Y248	16.6222	4.12	No	No	0	9	8
85	R:R:N174	R:R:R173	15.3699	4.82	No	No	0	9	9
86	R:R:C171	R:R:N174	14.1131	6.3	No	No	0	7	9
87	R:R:C171	R:R:K168	12.8516	3.23	No	No	0	7	8
88	R:R:E410	R:R:K168	11.5855	5.4	Yes	No	0	8	8
89	R:R:L307	R:R:W282	24.0901	9.11	No	Yes	12	7	9
90	R:R:L307	R:R:V236	24.1567	5.96	No	No	0	7	6
91	R:R:P275	R:R:V236	26.0455	3.53	Yes	No	0	9	6
92	R:R:P275	R:R:Y233	21.3396	6.95	Yes	Yes	4	9	9
93	R:R:W272	R:R:Y233	19.4347	4.82	Yes	Yes	4	9	9
94	R:R:W241	R:R:W272	17.1415	14.06	Yes	Yes	4	9	9
95	R:R:L180	R:R:W241	15.2688	6.83	Yes	Yes	0	9	9
96	R:R:I176	R:R:V244	12.8653	3.07	No	No	0	9	8
97	R:R:V244	R:R:Y267	11.5993	7.57	No	No	0	8	7
98	R:R:E245	R:R:L357	38.0653	3.98	Yes	Yes	0	9	9
99	R:R:F365	R:R:R308	11.7188	5.34	Yes	Yes	0	7	6
100	L:L:S11	R:R:T296	12.6884	6.4	No	No	0	0	5
101	L:L:S11	R:R:S297	14.483	3.26	No	No	0	0	4
102	R:R:Q293	R:R:S297	16.273	4.33	Yes	No	0	4	4
103	R:R:L357	R:R:L358	31.1098	8.3	Yes	Yes	0	9	9
104	R:R:L358	R:R:N318	14.051	15.1	Yes	No	0	9	9
105	R:R:G246	R:R:N318	12.7964	5.09	No	No	0	9	9
106	R:R:G246	R:R:I321	11.5372	3.53	No	No	0	9	8
107	R:R:H250	R:R:I321	10.2734	3.98	No	No	0	7	8
108	R:R:I355	R:R:L358	15.278	2.85	Yes	Yes	0	8	9
109	R:R:E290	R:R:V292	12.6884	4.28	No	No	0	6	4
110	R:R:E290	R:R:F289	10.8892	5.83	No	No	0	6	3
111	L:L:D15	R:R:Y202	29.3107	3.45	Yes	Yes	3	0	1
112	L:L:Q20	R:R:M123	68.6581	6.8	No	Yes	0	0	3
113	R:R:F184	R:R:L156	15.432	4.87	Yes	Yes	0	8	8
114	R:R:R201	R:R:W215	16.0133	13.99	No	Yes	3	4	2
115	R:R:L85	R:R:W87	66.3695	7.97	Yes	No	1	6	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:D299	R:R:Q27	13.05	0	No	No	4	5	1	2
R:R:P86	R:R:V28	3.53	1	Yes	Yes	3	3	2	1
L:L:D15	R:R:V28	4.38	3	Yes	Yes	0	3	0	1
R:R:M29	R:R:W215	6.98	3	No	Yes	5	2	1	1
L:L:D15	R:R:M29	8.32	3	Yes	No	0	5	0	1
L:L:R18	R:R:M29	6.2	3	No	No	0	5	0	1
R:R:L32	R:R:Y84	4.69	0	No	Yes	4	5	1	2
R:R:L32	R:R:P86	3.28	0	No	Yes	4	3	1	2
L:L:F22	R:R:L32	3.65	1	Yes	No	0	4	0	1
R:R:F33	R:R:S213	5.28	0	No	No	4	3	1	2
R:R:F33	R:R:L216	4.87	0	No	No	4	2	1	2
L:L:F22	R:R:F33	5.36	1	Yes	No	0	4	0	1
R:R:K37	R:R:W36	3.48	0	No	Yes	3	6	2	1
R:R:W36	R:R:Y84	10.61	1	Yes	Yes	6	5	1	2
R:R:D209	R:R:W36	7.82	0	No	Yes	4	6	1	1
L:L:F22	R:R:W36	4.01	1	Yes	Yes	0	6	0	1
L:L:L26	R:R:W36	5.69	1	Yes	Yes	0	6	0	1
R:R:D63	R:R:Y65	11.49	2	Yes	Yes	9	6	2	1
R:R:D63	R:R:S66	5.89	2	Yes	No	9	5	2	2
R:R:S66	R:R:Y65	5.09	2	No	Yes	5	6	2	1
R:R:R116	R:R:Y65	15.43	2	No	Yes	6	6	1	1
L:L:M27	R:R:Y65	15.57	2	Yes	Yes	0	6	0	1
R:R:P82	R:R:Y84	5.56	1	No	Yes	8	5	2	2
R:R:L85	R:R:P82	4.93	1	Yes	No	6	8	1	2
R:R:L85	R:R:P86	4.93	1	Yes	Yes	6	3	1	2
R:R:L85	R:R:W87	7.97	1	Yes	No	6	3	1	2
R:R:P86	R:R:W87	12.16	1	Yes	No	3	3	2	2
R:R:M123	R:R:W87	6.98	0	Yes	No	3	3	1	2
R:R:A118	R:R:R116	8.3	0	No	No	5	6	2	1
L:L:M27	R:R:R116	12.41	2	Yes	No	0	6	0	1
R:R:M123	R:R:Q122	5.44	0	Yes	No	3	3	1	2
R:R:I128	R:R:M123	5.83	0	No	Yes	2	3	2	1
L:L:Q20	R:R:M123	6.8	0	No	Yes	0	3	0	1
L:L:Y13	R:R:Q131	9.02	8	Yes	No	0	3	0	1
L:L:R17	R:R:Q131	7.01	8	No	No	0	3	0	1
L:L:Q20	R:R:Q131	10.24	0	No	No	0	3	0	1
R:R:M137	R:R:Y138	3.59	0	Yes	Yes	4	5	2	1
R:R:F141	R:R:M137	6.22	0	No	Yes	6	4	1	2
L:L:D9	R:R:Y138	4.6	0	No	Yes	0	5	0	1
L:L:Y10	R:R:Y138	6.95	0	No	Yes	0	5	0	1
L:L:Y13	R:R:Y138	3.97	8	Yes	Yes	0	5	0	1
R:R:F141	R:R:F383	8.57	0	No	No	6	5	1	2
L:L:F6	R:R:F141	5.36	0	No	No	0	6	0	1
R:R:D195	R:R:Q142	3.92	0	No	No	7	5	2	1
L:L:Y10	R:R:Q142	7.89	0	No	No	0	5	0	1
R:R:T146	R:R:Y145	6.24	0	No	Yes	7	7	2	1
R:R:Y145	R:R:Y149	7.94	5	Yes	Yes	7	8	1	1
R:R:V191	R:R:Y145	3.79	5	No	Yes	7	7	1	1
R:R:L386	R:R:Y145	3.52	0	No	Yes	7	7	1	1
L:L:F6	R:R:Y145	6.19	0	No	Yes	0	7	0	1
R:R:L192	R:R:T146	4.42	0	No	No	7	7	2	2
R:R:A188	R:R:Y149	5.34	0	No	Yes	8	8	2	1
R:R:V191	R:R:Y149	6.31	5	No	Yes	7	8	1	1
R:R:L192	R:R:Y149	3.52	0	No	Yes	7	8	2	1
L:L:Q3	R:R:Y149	5.64	5	No	Yes	0	8	0	1
R:R:I235	R:R:K187	5.82	0	No	No	5	8	1	2
R:R:K187	R:R:Y239	4.78	0	No	No	8	8	2	2
L:L:Q3	R:R:V191	5.73	5	No	No	0	7	0	1
R:R:I194	R:R:M231	5.83	0	No	Yes	6	6	2	1
R:R:R201	R:R:Y202	5.14	3	No	Yes	4	1	2	1
R:R:R201	R:R:W215	13.99	3	No	Yes	4	2	2	1
R:R:W215	R:R:Y202	4.82	3	Yes	Yes	2	1	1	1
R:R:Q293	R:R:Y202	4.51	3	Yes	Yes	4	1	1	1
L:L:L14	R:R:Y202	10.55	0	No	Yes	0	1	0	1
L:L:D15	R:R:Y202	3.45	3	Yes	Yes	0	1	0	1
L:L:R18	R:R:I206	7.52	3	No	No	0	4	0	1
L:L:W25	R:R:I206	5.87	0	Yes	No	0	4	0	1
L:L:W25	R:R:G207	4.22	0	Yes	No	0	1	0	1
L:L:W25	R:R:D209	8.93	0	Yes	No	0	4	0	1
R:R:L216	R:R:W215	4.56	0	No	Yes	2	2	2	1
L:L:R18	R:R:W215	14.99	3	No	Yes	0	2	0	1
R:R:M231	R:R:Q232	5.44	0	Yes	Yes	6	7	1	1
L:L:T7	R:R:M231	4.52	0	No	Yes	0	6	0	1
R:R:Q232	R:R:W282	6.57	12	Yes	Yes	7	9	1	2
R:R:L307	R:R:Q232	6.65	12	No	Yes	7	7	2	1
L:L:H1	R:R:Q232	4.95	0	Yes	Yes	0	7	0	1
L:L:H1	R:R:I235	9.28	0	Yes	No	0	5	0	1
R:R:L307	R:R:V236	5.96	12	No	No	7	6	2	2
R:R:V236	R:R:V311	4.81	0	No	No	6	8	2	1
R:R:V311	R:R:Y239	8.83	0	No	No	8	8	1	2
R:R:H361	R:R:Y239	14.16	13	Yes	No	8	8	2	2
R:R:L307	R:R:W282	9.11	12	No	Yes	7	9	2	2
R:R:Q293	R:R:S297	4.33	3	Yes	No	4	4	1	1
L:L:D15	R:R:Q293	10.44	3	Yes	Yes	0	4	0	1
R:R:C294	R:R:T296	3.38	0	No	No	9	5	2	1
L:L:S11	R:R:T296	6.4	0	No	No	0	5	0	1
L:L:S11	R:R:S297	3.26	0	No	No	0	4	0	1
R:R:N298	R:R:W304	23.73	0	No	Yes	6	6	1	1
L:L:S8	R:R:N298	8.94	0	No	No	0	6	0	1
R:R:M301	R:R:W304	4.65	0	No	Yes	5	6	2	1
R:R:R308	R:R:W304	10	0	Yes	Yes	6	6	1	1
R:R:D370	R:R:W304	8.93	14	No	Yes	4	6	1	1
L:L:T5	R:R:W304	3.64	14	Yes	Yes	0	6	0	1
R:R:F365	R:R:R308	5.34	13	Yes	Yes	7	6	2	1
R:R:R308	R:R:T369	3.88	0	Yes	No	6	7	1	2
L:L:H1	R:R:R308	3.39	0	Yes	Yes	0	6	0	1
L:L:H1	R:R:V311	8.3	0	Yes	No	0	8	0	1
R:R:F365	R:R:H361	9.05	13	Yes	Yes	7	8	2	2
R:R:D385	R:R:H361	10.08	13	No	Yes	7	8	1	2
R:R:D385	R:R:F365	3.58	13	No	Yes	7	7	1	2
R:R:D370	R:R:R378	7.15	14	No	No	4	4	1	1
L:L:T5	R:R:D370	14.45	14	Yes	No	0	4	0	1
L:L:D9	R:R:R378	5.96	0	No	No	0	4	0	1
L:L:T5	R:R:L382	5.9	14	Yes	No	0	5	0	1
L:L:S2	R:R:D385	5.89	0	No	No	0	7	0	1
L:L:Q3	R:R:L386	5.32	5	No	No	0	7	0	1
R:R:I206	R:R:V212	3.07	0	No	No	4	3	1	2
L:L:V23	R:R:L85	2.98	0	No	Yes	0	6	0	1
R:R:Q293	R:R:V292	2.87	3	Yes	No	4	4	1	2
R:R:K381	R:R:L382	2.82	0	Yes	No	7	5	2	1
L:L:K12	R:R:D299	2.77	0	No	No	0	4	0	1
L:L:Y13	R:R:A135	2.67	8	Yes	No	0	3	0	1
R:R:L198	R:R:Y202	2.34	0	No	Yes	6	1	2	1
R:R:Q204	R:R:W215	2.19	0	No	Yes	4	2	2	1
L:L:A19	R:R:V28	1.7	0	No	Yes	0	3	0	1
R:R:A228	R:R:T296	1.68	0	No	No	5	5	2	1
L:L:S16	R:R:V28	1.62	0	No	Yes	0	3	0	1
R:R:M231	R:R:S190	1.53	0	Yes	No	6	5	1	2
R:R:Q27	R:R:V292	1.43	0	No	No	5	4	2	2
L:L:L26	R:R:K64	1.41	1	Yes	No	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	6LML_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.23
Number of Linked Nodes	387
Number of Links	433
Number of Hubs	58
Number of Links mediated by Hubs	218
Number of Communities	15
Number of Nodes involved in Communities	78
Number of Links involved in Communities	98

Path Summary
Number Of Nodes in MetaPath	116
Number Of Links MetaPath	115
Number of Shortest Paths	114083
Length Of Smallest Path	3
Average Path Length	17.4683
Length of Longest Path	42
Minimum Path Strength	1.375
Average Path Strength	6.14745
Maximum Path Strength	16.865
Minimum Path Correlation	0.7
Average Path Correlation	0.961615
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	62.3699
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	49.1208
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • signaling receptor binding • molecular transducer activity • molecular function activator activity • signaling receptor activity • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • G protein-coupled receptor binding • glucagon receptor binding • hormone activity • identical protein binding • monosaccharide metabolic process • positive regulation of biological process • gluconeogenesis • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • small molecule metabolic process • regulation of carbohydrate metabolic process • regulation of glucose metabolic process • positive regulation of cellular process • positive regulation of gluconeogenesis • regulation of biosynthetic process • carbohydrate metabolic process • small molecule biosynthetic process • carbohydrate biosynthetic process • hexose metabolic process • primary metabolic process • monosaccharide biosynthetic process • hexose biosynthetic process • positive regulation of glucose metabolic process • biosynthetic process • regulation of gluconeogenesis • metabolic process • positive regulation of carbohydrate metabolic process • regulation of carbohydrate biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • glucose metabolic process • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of biological process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • negative regulation of cellular process • apoptotic process • programmed cell death • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • response to activity • protein kinase A signaling • negative regulation of execution phase of apoptosis • regulation of execution phase of apoptosis • execution phase of apoptosis • behavior • feeding behavior • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of biological quality • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • positive regulation of establishment of protein localization • carbohydrate homeostasis • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • positive regulation of peptide hormone secretion • intracellular glucose homeostasis • cellular response to carbohydrate stimulus • chemical homeostasis • response to glucose • glucose homeostasis • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • homeostatic process • positive regulation of secretion by cell • positive regulation of protein transport • positive regulation of hormone secretion • response to monosaccharide • response to carbohydrate • positive regulation of secretion • cellular response to hexose stimulus • intracellular chemical homeostasis • cellular response to monosaccharide stimulus • positive regulation of peptide secretion • cellular response to glucose stimulus • positive regulation of protein secretion • response to hexose • cellular homeostasis • positive regulation of transport • regulation of insulin secretion involved in cellular response to glucose stimulus • regulation of calcium ion import • regulation of calcium ion transport • positive regulation of calcium ion transport • positive regulation of calcium ion import • regulation of monoatomic ion transport • calcium ion transport • metal ion transport • positive regulation of monoatomic ion transport • monoatomic ion transport • calcium ion import • monoatomic cation transport • regulation of metal ion transport • endoplasmic reticulum lumen • endoplasmic reticulum • vesicle lumen • intracellular vesicle • cytoplasmic vesicle lumen • secretory granule lumen • cytoplasmic vesicle • secretory granule • secretory vesicle • glucagon receptor activity • peptide receptor activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • transmembrane signaling receptor activity • amide binding • peptide hormone binding • hormone binding • enzyme regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • GDP binding • purine ribonucleotide binding • ion binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • nucleoside-triphosphatase regulator activity • GTPase regulator activity • purine ribonucleoside triphosphate binding • guanyl-nucleotide exchange factor activity • nucleoside phosphate binding • purine nucleotide binding • small molecule binding • circulatory system process • regulation of blood pressure • blood circulation • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of gene expression • regulation of macromolecule biosynthetic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • hormone-mediated signaling pathway • energy derivation by oxidation of organic compounds • glycogen metabolic process • regulation of generation of precursor metabolites and energy • generation of precursor metabolites and energy • regulation of polysaccharide metabolic process • glucan metabolic process • polysaccharide metabolic process • energy reserve metabolic process • regulation of glycogen metabolic process • cellular response to nutrient levels • response to nutrient levels • cellular response to stress • response to stress • response to starvation • cellular response to starvation • cell surface receptor signaling pathway • response to nutrient • exocytosis • vesicle-mediated transport • endosome
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • FnI-like domain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Ras-like P-loop GTPases • FnI-like domain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P47871
Sequence	>6LML_nogp_Chain_R Q V M D F L F E K W K L Y G D Q C H H N L S L L P P P T E L V C N R T F D K Y S C W P D T P A N T T A N I S C P W Y L P W H H K V Q H R F V F K R C G P D G Q W V R G P R G Q P W R D A S Q C Q M D G R E I E V Q K E V A K M Y S S F Q V M Y T V G Y S L S L G A L L L A L A I L G G L S K L H C T R N A I H A N L F A S F V L K A S S V L V I D G L L R W R Y S Q K I G D D L S V S T W L S D G A V A G C R V A A V F M Q Y G I V A N Y C W L L V E G L Y L H N L L G L A T L P E R S F F S L Y L G I G W G A P M L F V V P W A V V K C L F E N V Q C W T S N D N M G F W W I L R F P V F L A I L I N F F I F V R I V Q L L V A K L R A R Q M H H T D Y K F R L A K S T L T L I P L L G V H E V V F M F V T D E H A Q G T L R S A K L F F D L F L S S F Q G L L V A V L Y C F L N K E V Q S E L R R R W H R W R L G Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	8YW4	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-	chim(NtGi1-Gs)/β1/γ22	3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW4 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Retatrutide	-		3.26	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW5	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.84	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW5 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Retatrutide	-		2.84	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WG8	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide	chim(NtGi1-Gs)/β1/γ2	2.71	2024-03-06	10.1038/s41421-024-00649-0
	8WG8 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide		2.71	2024-03-06	10.1038/s41421-024-00649-0
	8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	2.86	2024-03-06	10.1038/s41421-024-00649-0
	8WA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		2.86	2024-03-06	10.1038/s41421-024-00649-0
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	10.1038/s41421-024-00649-0
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	10.1073/pnas.2303696120
	8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.13	2023-10-18	10.1073/pnas.2306145120
	8ITM (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.13	2023-10-18	10.1073/pnas.2306145120
	8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/β1/γ2	3.23	2023-10-18	10.1073/pnas.2306145120
	8ITL (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-		3.23	2023-10-18	10.1073/pnas.2306145120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	10.1073/pnas.2303696120
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	10.1073/pnas.2303696120
	8JIT	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-	Gs/β1/γ2	2.91	2023-09-06	10.1073/pnas.2303696120
	8JIT (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-		2.91	2023-09-06	10.1073/pnas.2303696120
	8JRV	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Arrestin2	3.3	2023-08-16	10.1038/s41586-023-06420-x
	8JRU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	Arrestin2	3.5	2023-08-16	10.1038/s41586-023-06420-x
	8FU6	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/β1/γ2	2.9	2023-04-12	10.1016/j.cell.2023.02.028
	8FU6 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-		2.9	2023-04-12	10.1016/j.cell.2023.02.028
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	10.1016/j.apsb.2024.09.002
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	10.1021/jacs.4c12808
	8JIU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-	Gs/β1/γ2	2.76	2023-09-13	10.1073/pnas.2303696120
	8JIU (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-		2.76	2023-09-13	10.1073/pnas.2303696120
	8JIQ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-	Gs/β1/γ2	3.4	2023-09-13	10.1073/pnas.2303696120
	8JIQ (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-		3.4	2023-09-13	10.1073/pnas.2303696120
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	10.1073/pnas.2200155119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	10.1073/pnas.2200155119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774	chim(NtGi1-Gs)/β1/γ2	3.08	2022-04-13	10.1073/pnas.2116506119
	7RBT (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774		3.08	2022-04-13	10.1073/pnas.2116506119
	7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/β1/γ2	3.24	2022-04-13	10.1073/pnas.2116506119
	7RA3 (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		3.24	2022-04-13	10.1073/pnas.2116506119
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	10.1073/pnas.2116506119
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	10.1073/pnas.2116506119
	7V9L	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2022-04-06	10.1073/pnas.2106606118
	7V9L (No Gprot)	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-		2.6	2022-04-06	10.1073/pnas.2106606118
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	10.1038/s41467-022-28683-0
	7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-03-02	10.1038/s41467-022-28683-0
	7VAB (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-		3.2	2022-03-02	10.1038/s41467-022-28683-0
	7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	10.1038/s41467-022-28683-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7V35	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3.5	2022-03-02	10.1038/s41467-022-28683-0
	7V35 (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-		3.5	2022-03-02	10.1038/s41467-022-28683-0
	7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/β1/γ2	3.1	2022-02-23	10.1038/s41467-022-28683-0
	7FIN (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-		3.1	2022-02-23	10.1038/s41467-022-28683-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	10.1038/s41467-021-27760-0
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	10.1038/s41589-021-00945-w
	7V9M	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-	Gs/β1/γ2	3.29	2021-10-20	10.1073/pnas.2106606118
	7V9M (No Gprot)	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-		3.29	2021-10-20	10.1073/pnas.2106606118
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/β1/γ2	2.98	2021-08-04	10.7554/eLife.68719
	7DTY (No Gprot)	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-		2.98	2021-08-04	10.7554/eLife.68719
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	10.1038/s41467-021-24058-z
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	10.1016/j.str.2021.04.008
	7D68	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-	Gs/β1/γ2	3	2020-12-16	10.1038/s41422-020-00442-0
	7D68 (No Gprot)	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-		3	2020-12-16	10.1038/s41422-020-00442-0
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	10.1073/pnas.2014879117
	7CZ5	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-	Gs/β1/γ2	2.6	2020-11-18	10.1038/s41467-020-18945-0
	7CZ5 (No Gprot)	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-		2.6	2020-11-18	10.1038/s41467-020-18945-0
	7D3S	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	2.9	2020-11-04	10.1016/j.bbrc.2020.08.042
	7D3S (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		2.9	2020-11-04	10.1016/j.bbrc.2020.08.042
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	10.1038/s41422-020-0384-8
	6WPW	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/β1/γ2	3.1	2020-08-12	10.1126/science.aba3373
	6WPW (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-		3.1	2020-08-12	10.1126/science.aba3373
	6WZG	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	2.3	2020-08-12	10.1038/s41467-020-17791-4
	6WZG (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		2.3	2020-08-12	10.1038/s41467-020-17791-4
	6WI9	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/β1/γ2	4.3	2020-08-12	10.1038/s41467-020-17791-4
	6WI9 (No Gprot)	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-		4.3	2020-08-12	10.1038/s41467-020-17791-4
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	10.1038/s41589-020-0589-7
	6WHC	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-	Gs/β1/γ2	3.4	2020-05-27	10.1074/jbc.RA120.013793
	6WHC (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-		3.4	2020-05-27	10.1074/jbc.RA120.013793
	6LML	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gi1/β1/γ1	3.9	2020-04-01	10.1126/science.aaz5346
	6LML (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-		3.9	2020-04-01	10.1126/science.aaz5346
	6LMK	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gs/β1/γ2	3.7	2020-04-01	10.1126/science.aaz5346
	6LMK (No Gprot)	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-		3.7	2020-04-01	10.1126/science.aaz5346
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	10.1038/s41586-019-1902-z
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	10.1038/nature25773
	5YQZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon analogue	-	-	3	2018-01-17	10.1038/nature25153
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5XF1	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3.19	2017-05-24	10.1038/nature22363
	5XEZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3	2017-05-24	10.1038/nature22363
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	10.1038/nature22394
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
	5EE7	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	MK0893	-	2.5	2016-04-20	10.1038/nature17414
	4L6R	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	-	3.3	2013-07-24	10.1038/nature12393

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 6LML_nogp.zip

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