Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:H1 8.81667610
2L:L:E3 6.9975400
3L:L:F6 6.2425400
4L:L:F22 7.9025430
5L:L:W25 10.445430
6L:L:L26 7.126530
7R:R:W39 8.80667635
8R:R:Y42 6.3925436
9R:R:L56 4.3675442
10R:R:C62 4.54449
11R:R:F66 7.945407
12R:R:Y69 9.65333635
13R:R:W72 7.828549
14R:R:W87 5.555433
15R:R:Y88 6.55286734
16R:R:L89 7.255636
17R:R:W91 11.338534
18R:R:V95 4.9475434
19R:R:R102 8.678548
20R:R:F103 9.16464
21R:R:P119 6.495447
22R:R:S136 4.5425451
23R:R:E139 4.272552
24R:R:Y145 7.128505
25R:R:F156 7.0325406
26R:R:H180 8.286529
27R:R:L183 7.095429
28R:R:F184 5.05286728
29R:R:S186 5.205429
30R:R:F187 12.84408
31R:R:R190 6.402528
32R:R:R227 6.42518
33R:R:N240 11.115429
34R:R:Y241 6.82857727
35R:R:Y242 7.9975476
36R:R:W243 8.918529
37R:R:E247 8.765429
38R:R:W274 7.3825409
39R:R:P277 6.032579
40R:R:W284 11.3357718
41R:R:K288 9.625418
42R:R:Y289 10.564513
43R:R:W297 7.815419
44R:R:R299 9.564514
45R:R:N302 7.334514
46R:R:Y305 8.052513
47R:R:W306 10.438516
48R:R:R310 15.1575417
49R:R:F321 3.8925406
50R:R:L359 7.368529
51R:R:H363 7.664528
52R:R:E364 8.598527
53R:R:V370 5.5415
54R:R:T391 6.34426
55R:R:Q394 6.4575429
56R:R:L396 5.0975405
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:N240 R:R:S186 66.36215.96YesYes299
2R:R:S186 R:R:W243 49.2368.65YesYes299
3R:R:W243 R:R:W274 63.580414.99YesYes099
4R:R:W274 R:R:Y235 62.75068.68YesNo099
5R:R:P277 R:R:Y235 62.19738.34YesNo099
6R:R:P277 R:R:Y242 60.429912.52YesYes796
7R:R:I313 R:R:Y242 58.46136.04NoYes076
8L:L:H1 R:R:I313 58.16433.98YesNo007
9L:L:E3 R:R:R190 1003.49YesYes008
10R:R:N240 R:R:R190 78.038613.26YesYes298
11L:L:E3 R:R:L388 98.952210.6YesNo007
12L:L:H1 R:R:R299 21.093313.54YesYes104
13L:L:F6 R:R:L388 96.34183.65YesNo007
14L:L:F6 L:L:V10 97.9025.24YesNo000
15L:L:T7 L:L:V10 94.80064.76NoNo000
16L:L:T7 R:R:K197 94.319210.51NoNo007
17R:R:K197 R:R:L201 94.0755.64NoNo078
18L:L:L14 R:R:L201 93.82835.54NoNo008
19L:L:L14 R:R:M204 92.5597.07NoNo002
20L:L:E15 R:R:M204 91.76874.06NoNo002
21L:L:E15 R:R:S31 91.22984.31NoNo003
22R:R:E34 R:R:V30 33.44999.98NoNo034
23R:R:E34 R:R:S31 90.68142.87NoNo033
24R:R:P90 R:R:V30 32.16388.84NoNo034
25R:R:L89 R:R:P90 31.79384.93YesNo063
26R:R:E34 R:R:K38 57.2714.05NoNo034
27R:R:K38 R:R:Y88 47.384.78NoYes344
28R:R:L89 R:R:Y88 33.94083.52YesYes364
29R:R:L89 R:R:W91 62.385320.5YesYes364
30R:R:V95 R:R:W91 58.43856.13YesYes344
31R:R:C85 R:R:V95 53.4813.42NoYes094
32R:R:C126 R:R:C85 52.46927.28NoNo099
33R:R:C126 R:R:V100 51.45495.12NoNo097
34R:R:L123 R:R:V100 50.438310.43NoNo067
35R:R:L123 R:R:R121 49.41929.72NoNo066
36R:R:P119 R:R:R121 48.397810.09YesNo076
37R:R:P119 R:R:R102 24.11937.21YesYes478
38R:R:C62 R:R:R102 16.65556.96YesYes498
39R:R:L118 R:R:P119 17.7563.28NoYes037
40R:R:K113 R:R:L118 14.49175.64NoNo043
41R:R:K113 R:R:W120 12.28831.16NoNo046
42R:R:L183 R:R:W243 18.12483.42YesYes299
43R:R:E247 R:R:L183 47.670911.93YesYes299
44R:R:E247 R:R:L359 18.88527.95YesYes299
45R:R:L359 R:R:V398 14.57554.47YesNo298
46R:R:P358 R:R:V398 15.05577.07NoNo098
47R:R:L401 R:R:P358 13.27631.64NoNo089
48R:R:L401 R:R:M397 10.88371.41NoNo087
49R:R:E247 R:R:H180 26.880611.08YesYes299
50R:R:F184 R:R:H180 11.46573.39YesYes289
51R:R:H180 R:R:R176 17.06986.77YesNo099
52R:R:N177 R:R:R176 13.34333.62NoNo099
53R:R:L172 R:R:N177 12.40576.87NoNo099
54R:R:F187 R:R:L183 22.63448.53YesYes089
55L:L:H1 R:R:Q234 15.38983.71YesNo007
56R:R:Q234 R:R:W284 14.913212.05NoYes078
57R:R:K288 R:R:W284 39.07212.76YesYes188
58R:R:K288 R:R:W297 37.928411.6YesYes189
59R:R:R299 R:R:W284 16.62915YesYes148
60L:L:H1 R:R:I309 18.594211.93YesNo006
61R:R:I309 R:R:W284 15.258132.88NoYes068
62R:R:W297 R:R:Y289 16.789.65YesYes193
63R:R:S223 R:R:Y289 10.75325.09NoYes133
64R:R:R227 R:R:W297 10.67785YesYes189
65R:R:I317 R:R:Y241 14.37673.63NoYes277
66R:R:L384 R:R:R376 10.18447.29NoNo064
67R:R:F367 R:R:L384 10.882510.96NoNo076
68R:R:E387 R:R:F367 11.60225.83NoNo077
69R:R:E364 R:R:E387 13.07515.07YesNo077
70R:R:I317 R:R:N320 15.70117.08NoNo079
71R:R:N320 R:R:T362 18.35835.85NoNo096
72R:R:F324 R:R:T362 13.999512.97NoNo096
73R:R:F324 R:R:I328 10.2857.54NoNo097
74R:R:R190 R:R:Y241 15.89156.17YesYes287
75R:R:L183 R:R:S186 16.9984.5YesYes299
76R:R:F187 R:R:N240 18.045721.75YesYes089
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:H1 R:R:Q234 3.71 1 Yes No 0 7 0 1
L:L:H1 R:R:R299 13.54 1 Yes Yes 0 4 0 1
L:L:H1 R:R:W306 8.46 1 Yes Yes 0 6 0 1
L:L:H1 R:R:I309 11.93 1 Yes No 0 6 0 1
L:L:H1 R:R:R310 11.28 1 Yes Yes 0 7 0 1
L:L:H1 R:R:I313 3.98 1 Yes No 0 7 0 1
L:L:A2 R:R:Y241 4 0 No Yes 0 7 0 1
L:L:E3 R:R:R190 3.49 0 Yes Yes 0 8 0 1
L:L:E3 R:R:V194 7.13 0 Yes No 0 7 0 1
L:L:E3 R:R:M233 6.77 0 Yes No 0 6 0 1
L:L:E3 R:R:L388 10.6 0 Yes No 0 7 0 1
L:L:T5 R:R:R299 6.47 1 No Yes 0 4 0 1
L:L:T5 R:R:W306 4.85 1 No Yes 0 6 0 1
L:L:F6 R:R:F381 4.29 0 Yes No 0 3 0 1
L:L:F6 R:R:F385 11.79 0 Yes No 0 5 0 1
L:L:F6 R:R:L388 3.65 0 Yes No 0 7 0 1
L:L:T7 R:R:K197 10.51 0 No No 0 7 0 1
L:L:S8 R:R:T298 4.8 0 No No 0 5 0 1
L:L:V10 R:R:L142 4.47 0 No No 0 3 0 1
L:L:S12 R:R:T298 6.4 0 No No 0 5 0 1
L:L:Y13 R:R:E138 15.71 0 No No 0 2 0 1
L:L:Y13 R:R:L142 3.52 0 No No 0 3 0 1
L:L:L14 R:R:L201 5.54 0 No No 0 8 0 1
L:L:L14 R:R:M204 7.07 0 No No 0 2 0 1
L:L:E15 R:R:S31 4.31 0 No No 0 3 0 1
L:L:E15 R:R:M204 4.06 0 No No 0 2 0 1
L:L:A19 R:R:T35 3.36 0 No No 0 5 0 1
L:L:K20 R:R:W91 6.96 3 No Yes 0 4 0 1
L:L:K20 R:R:E128 5.4 3 No No 0 2 0 1
L:L:F22 R:R:W39 10.02 3 Yes Yes 0 5 0 1
L:L:F22 R:R:H212 9.05 3 Yes No 0 3 0 1
L:L:I23 R:R:Y69 3.63 3 No Yes 0 5 0 1
L:L:I23 R:R:L89 7.14 3 No Yes 0 6 0 1
L:L:W25 R:R:Q211 12.05 3 Yes No 0 3 0 1
L:L:W25 R:R:H212 15.87 3 Yes No 0 3 0 1
L:L:L26 R:R:W39 7.97 3 Yes Yes 0 5 0 1
L:L:L26 R:R:D68 8.14 3 Yes No 0 5 0 1
L:L:L26 R:R:Y69 5.86 3 Yes Yes 0 5 0 1
L:L:V27 R:R:Y69 18.93 0 No Yes 0 5 0 1
R:R:E34 R:R:V30 9.98 0 No No 3 4 2 2
R:R:T35 R:R:V30 3.17 0 No No 5 4 1 2
R:R:P90 R:R:V30 8.84 0 No No 3 4 2 2
R:R:S31 R:R:S33 4.89 0 No No 3 5 1 2
R:R:E34 R:R:S31 2.87 0 No No 3 3 2 1
R:R:R40 R:R:W39 5 0 No Yes 3 5 2 1
R:R:R43 R:R:W39 10 0 No Yes 5 5 2 1
R:R:D68 R:R:W39 11.17 3 No Yes 5 5 1 1
R:R:W39 R:R:Y88 8.68 3 Yes Yes 5 4 1 2
R:R:Q213 R:R:R40 9.35 0 No No 4 3 2 2
R:R:F66 R:R:R43 8.55 0 Yes No 7 5 2 2
R:R:D68 R:R:F66 4.78 3 No Yes 5 7 1 2
R:R:P86 R:R:Y69 16.69 3 No Yes 8 5 2 1
R:R:Y69 R:R:Y88 6.95 3 Yes Yes 5 4 1 2
R:R:L89 R:R:Y69 5.86 3 Yes Yes 6 5 1 1
R:R:P86 R:R:Y88 11.13 3 No Yes 8 4 2 2
R:R:L89 R:R:Y88 3.52 3 Yes Yes 6 4 1 2
R:R:L89 R:R:P90 4.93 3 Yes No 6 3 1 2
R:R:L89 R:R:W91 20.5 3 Yes Yes 6 4 1 1
R:R:N94 R:R:W91 5.65 3 No Yes 4 4 2 1
R:R:V95 R:R:W91 6.13 3 Yes Yes 4 4 2 1
R:R:E128 R:R:W91 17.45 3 No Yes 2 4 1 1
R:R:N94 R:R:V95 7.39 3 No Yes 4 4 2 2
R:R:K113 R:R:L118 5.64 0 No No 4 3 2 1
R:R:L118 R:R:P119 3.28 0 No Yes 3 7 1 2
R:R:E138 R:R:S136 7.19 5 No Yes 2 1 1 2
R:R:E139 R:R:S136 4.31 5 Yes Yes 2 1 1 2
R:R:E138 R:R:E139 7.61 5 No Yes 2 2 1 1
R:R:E139 R:R:L142 5.3 5 Yes No 2 3 1 1
R:R:E139 R:R:S143 2.87 5 Yes No 2 4 1 2
R:R:F385 R:R:L141 8.53 0 No No 5 5 1 2
R:R:F385 R:R:Y145 12.38 0 No Yes 5 5 1 2
R:R:L388 R:R:Y145 3.52 0 No Yes 7 5 1 2
R:R:R190 R:R:V237 3.92 2 Yes No 8 6 1 2
R:R:N240 R:R:R190 13.26 2 Yes Yes 9 8 2 1
R:R:R190 R:R:Y241 6.17 2 Yes Yes 8 7 1 1
R:R:R190 R:R:T391 5.17 2 Yes Yes 8 6 1 2
R:R:M233 R:R:S193 7.67 0 No No 6 5 1 2
R:R:K197 R:R:L201 5.64 0 No No 7 8 1 1
R:R:D215 R:R:M204 9.7 0 No No 3 2 2 1
R:R:H212 R:R:Q211 6.18 3 No No 3 3 1 1
R:R:Q211 R:R:Q213 3.84 3 No No 3 4 1 2
R:R:Q234 R:R:W284 12.05 0 No Yes 7 8 1 2
R:R:V237 R:R:Y241 6.31 2 No Yes 6 7 2 1
R:R:N240 R:R:Y241 3.49 2 Yes Yes 9 7 2 1
R:R:I317 R:R:Y241 3.63 2 No Yes 7 7 2 1
R:R:E364 R:R:Y241 17.96 2 Yes Yes 7 7 2 1
R:R:T391 R:R:Y241 6.24 2 Yes Yes 6 7 2 1
R:R:I313 R:R:Y242 6.04 0 No Yes 7 6 1 2
R:R:F280 R:R:I309 6.28 0 No No 5 6 2 1
R:R:R299 R:R:W284 5 1 Yes Yes 4 8 1 2
R:R:I309 R:R:W284 32.88 0 No Yes 6 8 1 2
R:R:S301 R:R:T298 3.2 1 No No 4 5 2 1
R:R:N302 R:R:R299 4.82 1 Yes Yes 4 4 2 1
R:R:R299 R:R:W306 17.99 1 Yes Yes 4 6 1 1
R:R:N302 R:R:S301 2.98 1 Yes No 4 4 2 2
R:R:R310 R:R:W306 15.99 1 Yes Yes 7 6 1 1
R:R:V370 R:R:W306 4.9 1 Yes Yes 5 6 2 1
R:R:L314 R:R:R310 25.51 0 No Yes 4 7 2 1
R:R:R310 R:R:V370 7.85 1 Yes Yes 7 5 1 2
R:R:E364 R:R:I317 4.1 2 Yes No 7 7 2 2
R:R:E364 R:R:T391 8.47 2 Yes Yes 7 6 2 2
L:L:K28 R:R:L118 2.82 0 No No 0 3 0 1
R:R:K202 R:R:Y205 2.39 0 No No 4 3 2 1
L:L:L14 R:R:Y205 2.34 0 No No 0 3 0 1
R:R:A92 R:R:L89 1.58 0 No Yes 5 6 2 1
L:L:Q17 R:R:E139 1.27 0 No Yes 0 2 0 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 5VAI_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.87
Number of Linked Nodes 372
Number of Links 428
Number of Hubs 56
Number of Links mediated by Hubs 201
Number of Communities 8
Number of Nodes involved in Communities 87
Number of Links involved in Communities 127
Path Summary
Number Of Nodes in MetaPath 77
Number Of Links MetaPath 76
Number of Shortest Paths 140523
Length Of Smallest Path 3
Average Path Length 23.7433
Length of Longest Path 52
Minimum Path Strength 1.215
Average Path Strength 7.18871
Maximum Path Strength 22.82
Minimum Path Correlation 0.7
Average Path Correlation 0.963798
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.85714
Average % Of Corr. Nodes 56.5681
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 42.5053
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtG1SGD4
Sequence
>5VAI_nogp_Chain_R
TVSLSETVQ KWREYRRQC QHFLTEAPP LATGLFCNR TFDDYACWP 
DGAPGSFVN VSCPWYLPW ASNVLQGHV YRFCTAEGH WLPKDNSSL 
PWRDLSECE ESSPEERLL SLYIIYTVG YALSFSALV IASAILLGF 
RHLHCTRNY IHLNLFASF ILRALSVFI KDAALKWMY STAAQQHQW 
DGLLSYQDS LGCRLVFLL MQYCVAANY YWLLVEGAY LYTLLAFAV 
FSEQRIFKL YLSIGWGVP LLFVIPWGI VKYLYEDEG CWTRNSNMN 
YWLIIRLPI LFAIGVNFL IFIRVICIV VSKLKANLM CKTDIKCRL 
AKSTLTLIP LLGTHEVIF AFVMDEHAR GTLRFVKLF TELSFTSFQ 
GLMVAILYC FVNNEVQME FRKSWERWR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6ORVB1PeptideGlucagonGLP-1Homo sapiens-TT-OAD2Gs/β1/γ232020-01-08doi.org/10.1038/s41586-019-1902-z
6ORV (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-TT-OAD232020-01-08doi.org/10.1038/s41586-019-1902-z
7E14B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 156022738Gs/β1/γ22.92021-07-07doi.org/10.1038/s41467-021-24058-z
7E14 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 1560227382.92021-07-07doi.org/10.1038/s41467-021-24058-z
7DUQB1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 156022738Gs/β1/γ22.52021-07-14doi.org/10.1038/s41467-021-24058-z
7DUQ (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 1560227382.52021-07-14doi.org/10.1038/s41467-021-24058-z
7DURB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/β1/γ23.32021-08-11doi.org/10.1038/s41467-021-24058-z
7DUR (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-PubChem 1560227383.32021-08-11doi.org/10.1038/s41467-021-24058-z
7EVMB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/β1/γ22.52021-08-11doi.org/10.1038/s41467-021-24058-z
7EVM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens-PubChem 1560227382.52021-08-11doi.org/10.1038/s41467-021-24058-z
5VEWB1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.72017-05-24doi.org/10.1038/nature22378
6LN2B1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-3.22020-03-18doi.org/10.1038/s41467-020-14934-5
6KJVB1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.82019-11-13doi.org/10.1107/S2052252519013496
6KK1B1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-2.82019-11-13doi.org/10.1107/S2052252519013496
6KK7B1PeptideGlucagonGLP-1Homo sapiens-PF-06372222-3.12019-11-13doi.org/10.1107/S2052252519013496
5VEXB1PeptideGlucagonGLP-1Homo sapiens-NNC0640-32017-05-17doi.org/10.1038/nature22378
9IVMB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)LSN3318839chim(NtGi1-Gs)/β2/γ23.222024-11-13doi.org/10.1016/j.apsb.2024.09.002
9IVM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)LSN33188393.222024-11-13doi.org/10.1016/j.apsb.2024.09.002
6VCBB1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN3160440Gs/β1/γ23.32020-07-22doi.org/10.1038/s41589-020-0589-7
6VCB (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN31604403.32020-07-22doi.org/10.1038/s41589-020-0589-7
9IVGB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ232024-11-27doi.org/10.1016/j.apsb.2024.09.002
9IVG (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)-32024-11-27doi.org/10.1016/j.apsb.2024.09.002
7RTBB1PeptideGlucagonGLP-1Homo sapiensPeptide-19-Gs/β1/γ22.142021-10-06doi.org/10.1016/j.bbrc.2021.09.016
7RTB (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-19-2.142021-10-06doi.org/10.1016/j.bbrc.2021.09.016
7KI0B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-Gs/β1/γ22.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7KI0 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-2.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7KI1B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-Gs/β1/γ22.52021-08-04doi.org/10.1016/j.celrep.2021.109374
7KI1 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-2.52021-08-04doi.org/10.1016/j.celrep.2021.109374
6X18B1PeptideGlucagonGLP-1Homo sapiensGLP-1-Gs/β1/γ22.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X18 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1-2.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X19B1PeptideGlucagonGLP-1Homo sapiensCHU-128-Gs/β1/γ22.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X19 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensCHU-128-2.12020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X1AB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/β1/γ22.52020-09-09doi.org/10.1016/j.molcel.2020.09.020
6X1A (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensDanuglipron-2.52020-09-09doi.org/10.1016/j.molcel.2020.09.020
7LCIB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/β1/γ22.92021-01-20doi.org/10.1016/j.str.2021.04.008
7LCI (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensDanuglipron-2.92021-01-20doi.org/10.1016/j.str.2021.04.008
7LCJB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--2.822021-01-20doi.org/10.1016/j.str.2021.04.008
7LCKB1PeptideGlucagonGLP-1Homo sapiensDanuglipron--3.242021-01-20doi.org/10.1016/j.str.2021.04.008
7S15B1PeptideGlucagonGLP-1Homo sapiensPubChem 134611223--3.82022-06-08doi.org/10.1021/acs.jmedchem.1c01856
9J1PB1PeptideGlucagonGLP-1Homo sapiensg1:Ox-chim(NtGi1-Gs)/β1/γ22.992025-02-26doi.org/10.1021/jacs.4c12808
9J1P (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensg1:Ox-2.992025-02-26doi.org/10.1021/jacs.4c12808
5VAIB1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-Gs/β1/γ24.12017-05-24doi.org/10.1038/nature22394
5VAI (No Gprot) B1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-4.12017-05-24doi.org/10.1038/nature22394
5NX2B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (Truncated)--3.72017-06-14doi.org/10.1038/nature22800
6B3JB1PeptideGlucagonGLP-1Homo sapiensExendin-P5-Gs/β1/γ23.32018-02-21doi.org/10.1038/nature25773
6B3J (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-P5-3.32018-02-21doi.org/10.1038/nature25773
8WG7B1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ22.542024-03-06doi.org/10.1038/s41421-024-00649-0
8WG7 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--2.542024-03-06doi.org/10.1038/s41421-024-00649-0
7C2EB1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-Gs/β1/γ24.22020-08-26doi.org/10.1038/s41422-020-0384-8
7C2E (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-4.22020-08-26doi.org/10.1038/s41422-020-0384-8
7LLLB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/β1/γ23.72022-01-12doi.org/10.1038/s41467-021-27760-0
7LLL (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-4-3.72022-01-12doi.org/10.1038/s41467-021-27760-0
7LLYB1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-Gs/β1/γ23.32022-01-12doi.org/10.1038/s41467-021-27760-0
7LLY (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-3.32022-01-12doi.org/10.1038/s41467-021-27760-0
7FIMB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-Gs/β1/γ23.42022-03-02doi.org/10.1038/s41467-022-28683-0
7FIM (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide-3.42022-03-02doi.org/10.1038/s41467-022-28683-0
7VBIB1PeptideGlucagonGLP-1Homo sapiensNon-Acylated Tirzepatide-Gs/β1/γ232022-03-02doi.org/10.1038/s41467-022-28683-0
7VBI (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensNon-Acylated Tirzepatide-32022-03-02doi.org/10.1038/s41467-022-28683-0
7VBHB1PeptideGlucagonGLP-1Homo sapiensPeptide-20-Gs/β1/γ232022-04-06doi.org/10.1038/s41467-022-28683-0
7VBH (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-20-32022-04-06doi.org/10.1038/s41467-022-28683-0
7S1MB1PeptideGlucagonGLP-1Homo sapiensEx4-D-Ala-Gs/β1/γ22.412022-01-05doi.org/10.1038/s41589-021-00945-w
7S1M (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensEx4-D-Ala-2.412022-01-05doi.org/10.1038/s41589-021-00945-w
7S3IB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ22.512022-01-05doi.org/10.1038/s41589-021-00945-w
7S3I (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--2.512022-01-05doi.org/10.1038/s41589-021-00945-w
6XOXB1PeptideGlucagonGLP-1Homo sapiensOrforglipron-chim(NtGi1-Gs)/β1/γ23.12020-11-18doi.org/10.1073/pnas.2014879117
6XOX (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensOrforglipron-3.12020-11-18doi.org/10.1073/pnas.2014879117
7RG9B1PeptideGlucagonGLP-1Homo sapiens--chim(NtGi1-Gs)/β1/γ23.22022-04-13doi.org/10.1073/pnas.2116506119
7RG9 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.22022-04-13doi.org/10.1073/pnas.2116506119
7RGPB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-chim(NtGi1-Gs)/β1/γ22.92022-04-13doi.org/10.1073/pnas.2116506119
7RGP (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensTirzepatide-2.92022-04-13doi.org/10.1073/pnas.2116506119
7X8RB1PeptideGlucagonGLP-1Homo sapiensBOC5-Gs/β1/γ22.612022-06-29doi.org/10.1073/pnas.2200155119
7X8R (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensBOC5-2.612022-06-29doi.org/10.1073/pnas.2200155119
7X8SB1PeptideGlucagonGLP-1Homo sapiensWB4-24-Gs/β1/γ23.092022-06-29doi.org/10.1073/pnas.2200155119
7X8S (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensWB4-24-3.092022-06-29doi.org/10.1073/pnas.2200155119
8JIPB1PeptideGlucagonGLP-1Homo sapiensMEDI0382-chim(NtGi1-Gs)/β1/γ22.852023-09-06doi.org/10.1073/pnas.2303696120
8JIP (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensMEDI0382-2.852023-09-06doi.org/10.1073/pnas.2303696120
8JIRB1PeptideGlucagonGLP-1Homo sapiensSAR425899-chim(NtGi1-Gs)/β1/γ22.572023-09-06doi.org/10.1073/pnas.2303696120
8JIR (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensSAR425899-2.572023-09-06doi.org/10.1073/pnas.2303696120
8JISB1PeptideGlucagonGLP-1Homo sapiensPeptide-15-chim(NtGi1-Gs)/β1/γ22.462023-11-08doi.org/10.1073/pnas.2303696120
8JIS (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensPeptide-15-2.462023-11-08doi.org/10.1073/pnas.2303696120
8YW3B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-Gs/β1/γ22.682024-09-18doi.org/10.1038/s41421-024-00700-0
8YW3 (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-2.682024-09-18doi.org/10.1038/s41421-024-00700-0
9EBNB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ23.442025-03-26doi.org/10.1073/pnas.2407574122
9EBN (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.442025-03-26doi.org/10.1073/pnas.2407574122
9EBOB1PeptideGlucagonGLP-1Homo sapiensGLP-1 (ACPC18)-Gs/β1/γ23.132025-03-26doi.org/10.1073/pnas.2407574122
9EBO (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensGLP-1 (ACPC18)-3.132025-03-26doi.org/10.1073/pnas.2407574122
9EBQB1PeptideGlucagonGLP-1Homo sapiens--Gs/β1/γ23.162025-03-26doi.org/10.1073/pnas.2407574122
9EBQ (No Gprot) B1PeptideGlucagonGLP-1Homo sapiens--3.162025-03-26doi.org/10.1073/pnas.2407574122
8YWFB1PeptideGlucagonGLP-1Homo sapiensRetatrutide-chim(NtGi1-Gs)/β1/γ22.742025-04-16To be published
8YWF (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensRetatrutide-2.742025-04-16To be published
9BYOB1PeptideGlucagonGLP-1Homo sapiensExendin-3-Gs/β1/γ22.312025-06-11To be published
9BYO (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-3-2.312025-06-11To be published
9C0KB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/β1/γ22.722025-06-11To be published
9C0K (No Gprot) B1PeptideGlucagonGLP-1Homo sapiensExendin-4-2.722025-06-11To be published




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