psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:H1	R:R:Q234	3.71	Yes	No	0	0	7
2	L:L:H1	R:R:R299	13.54	Yes	Yes	1	0	4
3	L:L:H1	R:R:W306	8.46	Yes	Yes	1	0	6
4	L:L:H1	R:R:I309	11.93	Yes	No	0	0	6
5	L:L:H1	R:R:R310	11.28	Yes	Yes	1	0	7
6	L:L:H1	R:R:I313	3.98	Yes	No	0	0	7
7	L:L:A2	R:R:Y241	4	No	Yes	0	0	7
8	L:L:E3	R:R:R190	3.49	Yes	Yes	0	0	8
9	L:L:E3	R:R:V194	7.13	Yes	No	0	0	7
10	L:L:E3	R:R:M233	6.77	Yes	No	0	0	6
11	L:L:E3	R:R:L388	10.6	Yes	No	0	0	7
12	L:L:T5	R:R:R299	6.47	No	Yes	1	0	4
13	L:L:T5	R:R:W306	4.85	No	Yes	1	0	6
14	L:L:F6	L:L:V10	5.24	Yes	No	0	0	0
15	L:L:F6	R:R:F381	4.29	Yes	No	0	0	3
16	L:L:F6	R:R:F385	11.79	Yes	No	0	0	5
17	L:L:F6	R:R:L388	3.65	Yes	No	0	0	7
18	L:L:T7	L:L:V10	4.76	No	No	0	0	0
19	L:L:T7	R:R:K197	10.51	No	No	0	0	7
20	L:L:S8	R:R:T298	4.8	No	No	0	0	5
21	L:L:D9	L:L:Y13	10.34	No	No	0	0	0
22	L:L:V10	R:R:L142	4.47	No	No	0	0	3
23	L:L:S12	R:R:T298	6.4	No	No	0	0	5
24	L:L:Y13	R:R:E138	15.71	No	No	0	0	2
25	L:L:Y13	R:R:L142	3.52	No	No	0	0	3
26	L:L:L14	R:R:L201	5.54	No	No	0	0	8
27	L:L:L14	R:R:M204	7.07	No	No	0	0	2
28	L:L:E15	R:R:S31	4.31	No	No	0	0	3
29	L:L:E15	R:R:M204	4.06	No	No	0	0	2
30	L:L:A19	R:R:T35	3.36	No	No	0	0	5
31	L:L:I23	L:L:K20	2.91	No	No	3	0	0
32	L:L:K20	R:R:W91	6.96	No	Yes	3	0	4
33	L:L:K20	R:R:E128	5.4	No	No	3	0	2
34	L:L:F22	L:L:W25	4.01	Yes	Yes	3	0	0
35	L:L:F22	L:L:L26	8.53	Yes	Yes	3	0	0
36	L:L:F22	R:R:W39	10.02	Yes	Yes	3	0	5
37	L:L:F22	R:R:H212	9.05	Yes	No	3	0	3
38	L:L:I23	R:R:Y69	3.63	No	Yes	3	0	5
39	L:L:I23	R:R:L89	7.14	No	Yes	3	0	6
40	L:L:G31	L:L:W25	9.85	No	Yes	0	0	0
41	L:L:W25	R:R:Q211	12.05	Yes	No	3	0	3
42	L:L:W25	R:R:H212	15.87	Yes	No	3	0	3
43	L:L:G31	L:L:L26	5.13	No	Yes	0	0	0
44	L:L:L26	R:R:W39	7.97	Yes	Yes	3	0	5
45	L:L:L26	R:R:D68	8.14	Yes	No	3	0	5
46	L:L:L26	R:R:Y69	5.86	Yes	Yes	3	0	5
47	L:L:V27	R:R:Y69	18.93	No	Yes	0	0	5
48	R:R:E34	R:R:V30	9.98	No	No	0	3	4
49	R:R:T35	R:R:V30	3.17	No	No	0	5	4
50	R:R:P90	R:R:V30	8.84	No	No	0	3	4
51	R:R:S31	R:R:S33	4.89	No	No	0	3	5
52	R:R:E34	R:R:S31	2.87	No	No	0	3	3
53	R:R:L32	R:R:V36	2.98	No	No	0	5	3
54	R:R:E34	R:R:K38	4.05	No	No	0	3	4
55	R:R:R40	R:R:V36	6.54	No	No	0	3	3
56	R:R:K38	R:R:W87	9.28	No	Yes	3	4	3
57	R:R:K38	R:R:Y88	4.78	No	Yes	3	4	4
58	R:R:R40	R:R:W39	5	No	Yes	0	3	5
59	R:R:R43	R:R:W39	10	No	Yes	0	5	5
60	R:R:D68	R:R:W39	11.17	No	Yes	3	5	5
61	R:R:W39	R:R:Y88	8.68	Yes	Yes	3	5	4
62	R:R:Q213	R:R:R40	9.35	No	No	0	4	3
63	R:R:E41	R:R:R44	16.28	No	No	0	4	3
64	R:R:E41	R:R:Q45	3.82	No	No	0	4	5
65	R:R:F66	R:R:Y42	3.09	Yes	Yes	0	7	6
66	R:R:P86	R:R:Y42	9.74	No	Yes	3	8	6
67	R:R:W87	R:R:Y42	5.79	Yes	Yes	3	3	6
68	R:R:Y42	R:R:Y88	6.95	Yes	Yes	3	6	4
69	R:R:F66	R:R:R43	8.55	Yes	No	0	7	5
70	R:R:H48	R:R:Q45	3.71	No	No	0	4	5
71	R:R:Q45	R:R:W87	3.29	No	Yes	0	5	3
72	R:R:C46	R:R:L50	4.76	No	No	0	9	5
73	R:R:C46	R:R:F66	15.36	No	Yes	0	9	7
74	R:R:C46	R:R:C71	7.28	No	No	0	9	9
75	R:R:F49	R:R:H48	22.63	No	No	0	3	4
76	R:R:E52	R:R:H48	7.39	No	No	0	3	4
77	R:R:C71	R:R:F49	4.19	No	No	0	9	3
78	R:R:L50	R:R:R64	14.58	No	No	0	5	5
79	R:R:A53	R:R:R64	6.91	No	No	0	3	5
80	R:R:F61	R:R:L56	4.87	No	Yes	4	3	2
81	R:R:D74	R:R:L56	8.14	No	Yes	4	4	2
82	R:R:G59	R:R:T58	5.46	No	No	0	3	1
83	R:R:L60	R:R:T58	11.79	No	No	0	1	1
84	R:R:D74	R:R:F61	11.94	No	No	4	4	3
85	R:R:F61	R:R:P77	2.89	No	No	0	3	6
86	R:R:C62	R:R:R102	6.96	Yes	Yes	4	9	8
87	R:R:C104	R:R:C62	7.28	No	Yes	4	9	9
88	R:R:T65	R:R:W72	12.13	No	Yes	0	5	9
89	R:R:D68	R:R:F66	4.78	No	Yes	0	5	7
90	R:R:D67	R:R:W72	8.93	No	Yes	0	9	9
91	R:R:P86	R:R:Y69	16.69	No	Yes	3	8	5
92	R:R:Y69	R:R:Y88	6.95	Yes	Yes	3	5	4
93	R:R:L89	R:R:Y69	5.86	Yes	Yes	3	6	5
94	R:R:A70	R:R:V83	3.39	No	No	0	5	5
95	R:R:V83	R:R:W72	3.68	No	Yes	0	5	9
96	R:R:R102	R:R:W72	9	Yes	Yes	4	8	9
97	R:R:P119	R:R:W72	5.4	Yes	Yes	4	7	9
98	R:R:D74	R:R:G75	6.71	No	No	4	4	7
99	R:R:A76	R:R:S79	3.42	No	No	0	1	5
100	R:R:F80	R:R:Y101	14.44	No	No	6	4	5
101	R:R:F103	R:R:F80	11.79	Yes	No	6	4	4
102	R:R:R102	R:R:V81	5.23	Yes	No	0	8	6
103	R:R:H99	R:R:N82	8.93	No	No	0	3	4
104	R:R:H99	R:R:S84	4.18	No	No	0	3	4
105	R:R:C85	R:R:V95	3.42	No	Yes	0	9	4
106	R:R:C126	R:R:C85	7.28	No	No	0	9	9
107	R:R:P86	R:R:Y88	11.13	No	Yes	3	8	4
108	R:R:W87	R:R:Y88	3.86	Yes	Yes	3	3	4
109	R:R:L89	R:R:Y88	3.52	Yes	Yes	3	6	4
110	R:R:L89	R:R:P90	4.93	Yes	No	0	6	3
111	R:R:L89	R:R:W91	20.5	Yes	Yes	3	6	4
112	R:R:N94	R:R:W91	5.65	No	Yes	3	4	4
113	R:R:V95	R:R:W91	6.13	Yes	Yes	3	4	4
114	R:R:E128	R:R:W91	17.45	No	Yes	3	2	4
115	R:R:N94	R:R:V95	7.39	No	Yes	3	4	4
116	R:R:E125	R:R:G98	6.55	No	No	0	5	5
117	R:R:L123	R:R:V100	10.43	No	No	0	6	7
118	R:R:C126	R:R:V100	5.12	No	No	0	9	7
119	R:R:F103	R:R:Y101	12.38	Yes	No	6	4	5
120	R:R:W120	R:R:Y101	7.72	No	No	0	6	5
121	R:R:R102	R:R:W110	14.99	Yes	No	0	8	9
122	R:R:P119	R:R:R102	7.21	Yes	Yes	4	7	8
123	R:R:F103	R:R:L111	10.96	Yes	No	0	4	4
124	R:R:E107	R:R:T105	9.88	No	No	0	5	4
125	R:R:L111	R:R:P112	4.93	No	No	0	4	2
126	R:R:L111	R:R:W120	5.69	No	No	0	4	6
127	R:R:K113	R:R:S116	9.18	No	No	0	4	4
128	R:R:K113	R:R:L118	5.64	No	No	0	4	3
129	R:R:L118	R:R:P119	3.28	No	Yes	0	3	7
130	R:R:P119	R:R:R121	10.09	Yes	No	0	7	6
131	R:R:L123	R:R:R121	9.72	No	No	0	6	6
132	R:R:D122	R:R:S124	5.89	No	No	0	8	6
133	R:R:S135	R:R:S136	4.89	No	Yes	0	3	1
134	R:R:E138	R:R:S136	7.19	No	Yes	5	2	1
135	R:R:E139	R:R:S136	4.31	Yes	Yes	5	2	1
136	R:R:P137	R:R:R140	4.32	No	No	0	3	4
137	R:R:E138	R:R:E139	7.61	No	Yes	5	2	2
138	R:R:E139	R:R:L142	5.3	Yes	No	0	2	3
139	R:R:E139	R:R:S143	2.87	Yes	No	0	2	4
140	R:R:F385	R:R:L141	8.53	No	No	0	5	5
141	R:R:Y145	R:R:Y148	5.96	Yes	No	0	5	7
142	R:R:T149	R:R:Y145	11.24	No	Yes	0	6	5
143	R:R:F385	R:R:Y145	12.38	No	Yes	0	5	5
144	R:R:L388	R:R:Y145	3.52	No	Yes	0	7	5
145	R:R:D198	R:R:I146	4.2	No	No	0	8	4
146	R:R:F393	R:R:Y148	7.22	No	No	0	7	7
147	R:R:T149	R:R:Y152	4.99	No	No	0	6	8
148	R:R:S392	R:R:Y152	7.63	No	No	0	9	8
149	R:R:F393	R:R:Y152	8.25	No	No	0	7	8
150	R:R:L396	R:R:S155	10.51	Yes	No	0	5	9
151	R:R:F156	R:R:V160	7.87	Yes	No	0	6	3
152	R:R:F156	R:R:I188	8.79	Yes	No	0	6	7
153	R:R:A191	R:R:F156	4.16	No	Yes	0	7	6
154	R:R:F156	R:R:L192	7.31	Yes	No	0	6	3
155	R:R:F184	R:R:L159	8.53	Yes	No	0	8	9
156	R:R:I188	R:R:L159	7.14	No	No	0	7	9
157	R:R:L181	R:R:S163	3	No	No	2	6	6
158	R:R:F184	R:R:S163	3.96	Yes	No	2	8	6
159	R:R:F413	R:R:I165	3.77	No	No	0	5	8
160	R:R:L166	R:R:L181	8.3	No	No	2	8	6
161	R:R:F184	R:R:L166	3.65	Yes	No	2	8	8
162	R:R:C403	R:R:L166	4.76	No	No	2	9	8
163	R:R:F169	R:R:L172	9.74	No	No	0	8	9
164	R:R:E412	R:R:F169	5.83	No	No	0	8	8
165	R:R:L172	R:R:N177	6.87	No	No	0	9	9
166	R:R:L172	R:R:V409	4.47	No	No	0	9	9
167	R:R:H173	R:R:Y178	9.8	No	No	0	8	6
168	R:R:T175	R:R:Y250	9.99	No	No	0	7	8
169	R:R:N177	R:R:R176	3.62	No	No	0	9	9
170	R:R:H180	R:R:R176	6.77	Yes	No	0	9	9
171	R:R:R176	R:R:Y250	3.09	No	No	0	9	8
172	R:R:N182	R:R:Y178	9.3	No	No	0	8	6
173	R:R:F266	R:R:Y178	7.22	No	No	0	6	6
174	R:R:E247	R:R:I179	4.1	Yes	No	0	9	9
175	R:R:F266	R:R:I179	7.54	No	No	0	6	9
176	R:R:F184	R:R:H180	3.39	Yes	Yes	2	8	9
177	R:R:E247	R:R:H180	11.08	Yes	Yes	2	9	9
178	R:R:H180	R:R:L359	3.86	Yes	Yes	2	9	9
179	R:R:H180	R:R:Y402	16.33	Yes	No	2	9	8
180	R:R:F184	R:R:L181	6.09	Yes	No	2	8	6
181	R:R:N182	R:R:W243	10.17	No	Yes	0	8	9
182	R:R:L183	R:R:S186	4.5	Yes	Yes	2	9	9
183	R:R:F187	R:R:L183	8.53	Yes	Yes	0	8	9
184	R:R:L183	R:R:W243	3.42	Yes	Yes	2	9	9
185	R:R:E247	R:R:L183	11.93	Yes	Yes	2	9	9
186	R:R:A399	R:R:F184	4.16	No	Yes	0	8	8
187	R:R:C403	R:R:F184	5.59	No	Yes	2	9	8
188	R:R:N240	R:R:S186	5.96	Yes	Yes	2	9	9
189	R:R:S186	R:R:W243	8.65	Yes	Yes	2	9	9
190	R:R:F187	R:R:N240	21.75	Yes	Yes	0	8	9
191	R:R:F187	R:R:Q394	10.54	Yes	Yes	0	8	9
192	R:R:F187	R:R:G395	10.54	Yes	No	0	8	9
193	R:R:C236	R:R:L189	7.94	No	No	0	5	6
194	R:R:R190	R:R:V237	3.92	Yes	No	2	8	6
195	R:R:N240	R:R:R190	13.26	Yes	Yes	2	9	8
196	R:R:R190	R:R:Y241	6.17	Yes	Yes	2	8	7
197	R:R:R190	R:R:T391	5.17	Yes	Yes	2	8	6
198	R:R:M233	R:R:S193	7.67	No	No	0	6	5
199	R:R:C236	R:R:S193	6.89	No	No	0	5	5
200	R:R:I196	R:R:V229	3.07	No	No	0	5	6
201	R:R:K197	R:R:L201	5.64	No	No	0	7	8
202	R:R:D198	R:R:K202	5.53	No	No	0	8	4
203	R:R:D215	R:R:M204	9.7	No	No	0	3	2
204	R:R:D215	R:R:T207	7.23	No	No	0	3	1
205	R:R:H212	R:R:Q211	6.18	No	No	3	3	3
206	R:R:Q211	R:R:Q213	3.84	No	No	0	3	4
207	R:R:D222	R:R:S219	4.42	No	No	0	6	4
208	R:R:C226	R:R:D222	6.22	No	No	0	9	6
209	R:R:S223	R:R:Y289	5.09	No	Yes	1	3	3
210	R:R:D293	R:R:S223	5.89	No	No	1	6	3
211	R:R:C226	R:R:F230	5.59	No	No	1	9	6
212	R:R:C226	R:R:C296	7.28	No	No	1	9	9
213	R:R:L231	R:R:R227	4.86	No	Yes	0	6	8
214	R:R:R227	R:R:Y289	18.52	Yes	Yes	1	8	3
215	R:R:R227	R:R:W297	5	Yes	Yes	1	8	9
216	R:R:C296	R:R:F230	5.59	No	No	1	9	6
217	R:R:F230	R:R:W297	5.01	No	Yes	1	6	9
218	R:R:C236	R:R:L232	3.17	No	No	0	5	5
219	R:R:Q234	R:R:W284	12.05	No	Yes	0	7	8
220	R:R:W274	R:R:Y235	8.68	Yes	No	0	9	9
221	R:R:P277	R:R:Y235	8.34	Yes	No	0	9	9
222	R:R:L278	R:R:Y235	3.52	No	No	0	4	9
223	R:R:V237	R:R:Y241	6.31	No	Yes	2	6	7
224	R:R:A238	R:R:P277	3.74	No	Yes	0	5	9
225	R:R:N240	R:R:Y241	3.49	Yes	Yes	2	9	7
226	R:R:I317	R:R:Y241	3.63	No	Yes	2	7	7
227	R:R:E364	R:R:Y241	17.96	Yes	Yes	2	7	7
228	R:R:T391	R:R:Y241	6.24	Yes	Yes	2	6	7
229	R:R:L245	R:R:Y242	5.86	No	Yes	0	8	6
230	R:R:V276	R:R:Y242	7.57	No	Yes	7	4	6
231	R:R:P277	R:R:Y242	12.52	Yes	Yes	7	9	6
232	R:R:I313	R:R:Y242	6.04	No	Yes	0	7	6
233	R:R:V246	R:R:W243	7.36	No	Yes	0	8	9
234	R:R:W243	R:R:W274	14.99	Yes	Yes	0	9	9
235	R:R:L244	R:R:N320	5.49	No	No	0	9	9
236	R:R:L244	R:R:Q394	6.65	No	Yes	0	9	9
237	R:R:A316	R:R:L245	4.73	No	No	0	7	8
238	R:R:L245	R:R:V319	4.47	No	No	0	8	6
239	R:R:E247	R:R:L359	7.95	Yes	Yes	2	9	9
240	R:R:G248	R:R:I323	5.29	No	No	0	9	8
241	R:R:T253	R:R:Y269	3.75	No	No	0	7	7
242	R:R:A256	R:R:F257	4.16	No	No	0	6	5
243	R:R:E262	R:R:V259	9.98	No	No	0	6	8
244	R:R:F260	R:R:S261	11.89	No	No	0	6	6
245	R:R:I265	R:R:Y269	9.67	No	No	0	4	7
246	R:R:L270	R:R:W274	4.56	No	Yes	0	5	9
247	R:R:I272	R:R:V276	4.61	No	No	0	7	4
248	R:R:P277	R:R:V276	3.53	Yes	No	7	9	4
249	R:R:F280	R:R:V281	3.93	No	No	0	5	7
250	R:R:F280	R:R:I309	6.28	No	No	0	5	6
251	R:R:F280	R:R:P312	14.45	No	No	0	5	9
252	R:R:I282	R:R:P283	3.39	No	No	0	2	4
253	R:R:G285	R:R:W284	5.63	No	Yes	1	5	8
254	R:R:K288	R:R:W284	12.76	Yes	Yes	1	8	8
255	R:R:R299	R:R:W284	5	Yes	Yes	1	4	8
256	R:R:W284	R:R:Y305	8.68	Yes	Yes	1	8	3
257	R:R:I309	R:R:W284	32.88	No	Yes	0	6	8
258	R:R:G285	R:R:K288	6.97	No	Yes	1	5	8
259	R:R:K288	R:R:W297	11.6	Yes	Yes	1	8	9
260	R:R:K288	R:R:Y305	7.17	Yes	Yes	1	8	3
261	R:R:D293	R:R:Y289	18.39	No	Yes	1	6	3
262	R:R:W297	R:R:Y289	9.65	Yes	Yes	1	9	3
263	R:R:E292	R:R:Y291	7.86	No	No	1	5	3
264	R:R:Y291	R:R:Y305	4.96	No	Yes	1	3	3
265	R:R:E292	R:R:N302	6.57	No	Yes	1	5	4
266	R:R:E292	R:R:Y305	8.98	No	Yes	1	5	3
267	R:R:E294	R:R:S301	8.62	No	No	1	4	4
268	R:R:E294	R:R:N302	11.83	No	Yes	1	4	4
269	R:R:S301	R:R:T298	3.2	No	No	0	4	5
270	R:R:N302	R:R:R299	4.82	Yes	Yes	1	4	4
271	R:R:R299	R:R:W306	17.99	Yes	Yes	1	4	6
272	R:R:N300	R:R:R376	4.82	No	No	0	6	4
273	R:R:N302	R:R:S301	2.98	Yes	No	1	4	4
274	R:R:N302	R:R:Y305	10.47	Yes	Yes	1	4	3
275	R:R:R310	R:R:W306	15.99	Yes	Yes	1	7	6
276	R:R:V370	R:R:W306	4.9	Yes	Yes	1	5	6
277	R:R:D372	R:R:L307	5.43	No	No	0	5	6
278	R:R:L314	R:R:R310	25.51	No	Yes	0	4	7
279	R:R:R310	R:R:V370	7.85	Yes	Yes	1	7	5
280	R:R:L311	R:R:P312	3.28	No	No	0	4	9
281	R:R:F315	R:R:V319	3.93	No	No	0	4	6
282	R:R:I317	R:R:N320	7.08	No	No	0	7	9
283	R:R:E364	R:R:I317	4.1	Yes	No	2	7	7
284	R:R:I323	R:R:V319	3.07	No	No	0	8	6
285	R:R:N320	R:R:T362	5.85	No	No	0	9	6
286	R:R:F321	R:R:I325	7.54	Yes	No	0	6	5
287	R:R:F321	R:R:V365	3.93	Yes	No	0	6	6
288	R:R:L322	R:R:R326	3.64	No	No	0	4	8
289	R:R:F324	R:R:I328	7.54	No	No	0	9	7
290	R:R:F324	R:R:I357	10.05	No	No	0	9	8
291	R:R:F324	R:R:T362	12.97	No	No	0	9	6
292	R:R:L356	R:R:V327	2.98	No	No	0	9	9
293	R:R:I328	R:R:T353	6.08	No	No	0	7	9
294	R:R:L335	R:R:L339	5.54	No	No	0	8	6
295	R:R:K346	R:R:L335	4.23	No	No	0	6	8
296	R:R:L335	R:R:L349	4.15	No	No	0	8	8
297	R:R:K336	R:R:K346	8.62	No	No	0	7	6
298	R:R:D344	R:R:L349	10.86	No	No	0	6	8
299	R:R:K351	R:R:L354	5.64	No	No	0	8	8
300	R:R:I357	R:R:L354	4.28	No	No	0	8	8
301	R:R:L356	R:R:L359	4.15	No	Yes	0	9	9
302	R:R:L356	R:R:L360	5.54	No	No	0	9	9
303	R:R:I357	R:R:P358	3.39	No	No	0	8	9
304	R:R:P358	R:R:V398	7.07	No	No	0	9	8
305	R:R:L359	R:R:V398	4.47	Yes	No	2	9	8
306	R:R:L359	R:R:Y402	16.41	Yes	No	2	9	8
307	R:R:G361	R:R:H363	4.77	No	Yes	2	9	8
308	R:R:G361	R:R:Q394	4.93	No	Yes	2	9	9
309	R:R:E364	R:R:H363	7.39	Yes	Yes	2	7	8
310	R:R:F390	R:R:H363	16.97	No	Yes	0	6	8
311	R:R:H363	R:R:T391	5.48	Yes	Yes	2	8	6
312	R:R:H363	R:R:Q394	3.71	Yes	Yes	2	8	9
313	R:R:E364	R:R:E387	5.07	Yes	No	0	7	7
314	R:R:E364	R:R:T391	8.47	Yes	Yes	2	7	6
315	R:R:F367	R:R:L384	10.96	No	No	0	7	6
316	R:R:E387	R:R:F367	5.83	No	No	0	7	7
317	R:R:F369	R:R:V370	7.87	No	Yes	0	5	5
318	R:R:F369	R:R:R380	16.03	No	No	0	5	6
319	R:R:H374	R:R:M371	10.51	No	No	0	4	8
320	R:R:D372	R:R:E373	6.5	No	No	0	5	4
321	R:R:L384	R:R:R376	7.29	No	No	0	6	4
322	R:R:S389	R:R:T386	3.2	No	No	0	5	4
323	R:R:I400	R:R:L396	4.28	No	Yes	0	5	5
324	R:R:V398	R:R:Y402	5.05	No	No	2	8	8
325	R:R:F404	R:R:I400	6.28	No	No	0	9	5
326	R:R:F404	R:R:V405	3.93	No	No	0	9	5
327	R:R:E408	R:R:N406	10.52	No	No	0	9	9
328	R:R:N406	R:R:V409	5.91	No	No	0	9	9
329	R:R:R414	R:R:W417	16.99	No	No	0	6	6
330	R:R:K415	R:R:R419	3.71	No	No	0	7	6
331	R:R:S416	R:R:W420	6.18	No	No	0	5	4
332	R:R:E418	R:R:W417	4.36	No	No	8	4	6
333	R:R:R421	R:R:W417	4	No	No	8	5	6
334	R:R:E418	R:R:R421	3.49	No	No	8	4	5
335	R:R:E125	R:R:V95	2.85	No	Yes	0	5	4
336	R:R:L396	R:R:M397	2.83	Yes	No	0	5	7
337	L:L:K28	R:R:L118	2.82	No	No	0	0	3
338	R:R:E52	R:R:T51	2.82	No	No	0	3	3
339	R:R:L154	R:R:L396	2.77	No	Yes	0	6	5
340	R:R:D372	R:R:M371	2.77	No	No	0	5	8
341	R:R:L56	R:R:N63	2.75	Yes	No	0	2	5
342	R:R:F321	R:R:T362	2.59	Yes	No	0	6	6
343	R:R:S389	R:R:Y145	2.54	No	Yes	0	5	5
344	R:R:V246	R:R:Y269	2.52	No	No	0	8	7
345	R:R:I286	R:R:R227	2.51	No	Yes	0	3	8
346	R:R:K202	R:R:Y205	2.39	No	No	0	4	3
347	R:R:I308	R:R:W284	2.35	No	Yes	0	8	8
348	L:L:L14	R:R:Y205	2.34	No	No	0	0	3
349	R:R:Q47	R:R:R44	2.34	No	No	0	1	3
350	R:R:L254	R:R:Y250	2.34	No	No	0	8	8
351	R:R:L217	R:R:W214	2.28	No	No	0	2	4
352	R:R:L218	R:R:W214	2.28	No	No	0	4	4
353	R:R:F169	R:R:H171	2.26	No	No	0	8	8
354	R:R:G108	R:R:P77	2.03	No	No	0	9	6
355	R:R:G275	R:R:P277	2.03	No	Yes	0	6	9
356	R:R:C62	R:R:G75	1.96	Yes	No	4	9	7
357	R:R:C62	R:R:G108	1.96	Yes	No	0	9	9
358	R:R:C104	R:R:G75	1.96	No	No	4	9	7
359	R:R:P54	R:R:P55	1.95	No	No	0	3	2
360	R:R:A106	R:R:G78	1.95	No	No	0	2	7
361	R:R:A53	R:R:P54	1.87	No	No	0	3	3
362	R:R:A76	R:R:P77	1.87	No	No	0	1	6
363	R:R:G216	R:R:S219	1.86	No	No	0	3	4
364	R:R:G273	R:R:V246	1.84	No	No	0	9	8
365	L:L:G4	L:L:T7	1.82	No	No	0	0	0
366	R:R:P137	R:R:S136	1.78	No	Yes	0	3	1
367	R:R:P73	R:R:V81	1.77	No	No	0	5	6
368	R:R:P73	R:R:V83	1.77	No	No	0	5	5
369	L:L:G29	L:L:K28	1.74	No	No	0	0	0
370	R:R:G59	R:R:L56	1.71	No	Yes	0	3	2
371	R:R:G168	R:R:L167	1.71	No	No	0	3	3
372	R:R:A239	R:R:S186	1.71	No	Yes	0	7	9
373	R:R:G225	R:R:L224	1.71	No	No	0	4	4
374	R:R:G225	R:R:L228	1.71	No	No	0	4	4
375	R:R:A200	R:R:V229	1.7	No	No	0	5	6
376	R:R:A368	R:R:V365	1.7	No	No	0	6	6
377	R:R:A249	R:R:T253	1.68	No	No	0	6	7
378	R:R:D293	R:R:G295	1.68	No	No	0	6	4
379	L:L:E15	L:L:G16	1.64	No	No	0	0	0
380	R:R:C329	R:R:I325	1.64	No	No	0	7	5
381	R:R:L401	R:R:P358	1.64	No	No	0	8	9
382	L:L:S11	L:L:S8	1.63	No	No	0	0	0
383	R:R:A158	R:R:I400	1.62	No	No	0	6	5
384	R:R:V327	R:R:V331	1.6	No	No	0	9	9
385	R:R:T386	R:R:V382	1.59	No	No	0	4	4
386	R:R:A92	R:R:L89	1.58	No	Yes	0	5	6
387	R:R:C341	R:R:N338	1.57	No	No	0	5	6
388	R:R:I265	R:R:S261	1.55	No	No	0	4	6
389	R:R:I165	R:R:V409	1.54	No	No	0	8	9
390	R:R:I265	R:R:V259	1.54	No	No	0	4	8
391	R:R:I282	R:R:V281	1.54	No	No	0	2	7
392	R:R:I286	R:R:V287	1.54	No	No	0	3	5
393	R:R:I328	R:R:V332	1.54	No	No	0	7	6
394	R:R:K267	R:R:S271	1.53	No	No	0	3	2
395	R:R:K336	R:R:V332	1.52	No	No	0	7	6
396	R:R:F103	R:R:G78	1.51	Yes	No	0	4	7
397	R:R:F321	R:R:G318	1.51	Yes	No	0	6	4
398	R:R:L144	R:R:S143	1.5	No	No	0	5	4
399	R:R:G377	R:R:R376	1.5	No	No	0	5	4
400	R:R:G377	R:R:R380	1.5	No	No	0	5	6
401	R:R:L251	R:R:V327	1.49	No	No	0	9	9
402	R:R:L401	R:R:T355	1.47	No	No	0	8	8
403	R:R:I330	R:R:K334	1.45	No	No	0	8	9
404	R:R:Q210	R:R:S206	1.44	No	No	0	1	3
405	R:R:E412	R:R:S416	1.44	No	No	0	8	5
406	R:R:L401	R:R:M397	1.41	No	No	0	8	7
407	R:R:D344	R:R:I345	1.4	No	No	0	6	7
408	R:R:A162	R:R:F404	1.39	No	No	0	8	9
409	R:R:H374	R:R:V370	1.38	No	Yes	0	4	5
410	R:R:H109	R:R:T105	1.37	No	No	0	6	4
411	R:R:E387	R:R:I366	1.37	No	No	0	7	6
412	R:R:E412	R:R:K415	1.35	No	No	0	8	7
413	R:R:L96	R:R:Q97	1.33	No	No	0	4	1
414	R:R:L218	R:R:Q221	1.33	No	No	0	4	3
415	R:R:R264	R:R:S261	1.32	No	No	0	5	6
416	R:R:D122	R:R:E125	1.3	No	No	0	8	5
417	R:R:A185	R:R:W274	1.3	No	Yes	0	4	9
418	L:L:Q17	R:R:E139	1.27	No	Yes	0	0	2
419	R:R:S223	R:R:Y220	1.27	No	No	0	3	4
420	R:R:K351	R:R:R348	1.24	No	No	0	8	9
421	R:R:K383	R:R:R380	1.24	No	No	0	8	6
422	R:R:L224	R:R:R227	1.21	No	Yes	0	4	8
423	R:R:I323	R:R:Y252	1.21	No	No	0	8	8
424	R:R:L217	R:R:Y220	1.17	No	No	0	2	4
425	R:R:L290	R:R:Y289	1.17	No	Yes	0	1	3
426	R:R:K113	R:R:W120	1.16	No	No	0	4	6
427	R:R:L218	R:R:W203	1.14	No	No	0	4	3
428	R:R:H109	R:R:W110	1.06	No	No	0	6	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:H1	8.81667	6	1	0
2	L:L:E3	6.9975	4	0	0
3	L:L:F6	6.2425	4	0	0
4	L:L:F22	7.9025	4	3	0
5	L:L:W25	10.445	4	3	0
6	L:L:L26	7.126	5	3	0
7	R:R:W39	8.80667	6	3	5
8	R:R:Y42	6.3925	4	3	6
9	R:R:L56	4.3675	4	4	2
10	R:R:C62	4.54	4	4	9
11	R:R:F66	7.945	4	0	7
12	R:R:Y69	9.65333	6	3	5
13	R:R:W72	7.828	5	4	9
14	R:R:W87	5.555	4	3	3
15	R:R:Y88	6.55286	7	3	4
16	R:R:L89	7.255	6	3	6
17	R:R:W91	11.338	5	3	4
18	R:R:V95	4.9475	4	3	4
19	R:R:R102	8.678	5	4	8
20	R:R:F103	9.16	4	6	4
21	R:R:P119	6.495	4	4	7
22	R:R:S136	4.5425	4	5	1
23	R:R:E139	4.272	5	5	2
24	R:R:Y145	7.128	5	0	5
25	R:R:F156	7.0325	4	0	6
26	R:R:H180	8.286	5	2	9
27	R:R:L183	7.095	4	2	9
28	R:R:F184	5.05286	7	2	8
29	R:R:S186	5.205	4	2	9
30	R:R:F187	12.84	4	0	8
31	R:R:R190	6.402	5	2	8
32	R:R:R227	6.42	5	1	8
33	R:R:N240	11.115	4	2	9
34	R:R:Y241	6.82857	7	2	7
35	R:R:Y242	7.9975	4	7	6
36	R:R:W243	8.918	5	2	9
37	R:R:E247	8.765	4	2	9
38	R:R:W274	7.3825	4	0	9
39	R:R:P277	6.032	5	7	9
40	R:R:W284	11.3357	7	1	8
41	R:R:K288	9.625	4	1	8
42	R:R:Y289	10.564	5	1	3
43	R:R:W297	7.815	4	1	9
44	R:R:R299	9.564	5	1	4
45	R:R:N302	7.334	5	1	4
46	R:R:Y305	8.052	5	1	3
47	R:R:W306	10.438	5	1	6
48	R:R:R310	15.1575	4	1	7
49	R:R:F321	3.8925	4	0	6
50	R:R:L359	7.368	5	2	9
51	R:R:H363	7.664	5	2	8
52	R:R:E364	8.598	5	2	7
53	R:R:V370	5.5	4	1	5
54	R:R:T391	6.34	4	2	6
55	R:R:Q394	6.4575	4	2	9
56	R:R:L396	5.0975	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:N240	R:R:S186	66.3621	5.96	Yes	Yes	2	9	9
2	R:R:S186	R:R:W243	49.236	8.65	Yes	Yes	2	9	9
3	R:R:W243	R:R:W274	63.5804	14.99	Yes	Yes	0	9	9
4	R:R:W274	R:R:Y235	62.7506	8.68	Yes	No	0	9	9
5	R:R:P277	R:R:Y235	62.1973	8.34	Yes	No	0	9	9
6	R:R:P277	R:R:Y242	60.4299	12.52	Yes	Yes	7	9	6
7	R:R:I313	R:R:Y242	58.4613	6.04	No	Yes	0	7	6
8	L:L:H1	R:R:I313	58.1643	3.98	Yes	No	0	0	7
9	L:L:E3	R:R:R190	100	3.49	Yes	Yes	0	0	8
10	R:R:N240	R:R:R190	78.0386	13.26	Yes	Yes	2	9	8
11	L:L:E3	R:R:L388	98.9522	10.6	Yes	No	0	0	7
12	L:L:H1	R:R:R299	21.0933	13.54	Yes	Yes	1	0	4
13	L:L:F6	R:R:L388	96.3418	3.65	Yes	No	0	0	7
14	L:L:F6	L:L:V10	97.902	5.24	Yes	No	0	0	0
15	L:L:T7	L:L:V10	94.8006	4.76	No	No	0	0	0
16	L:L:T7	R:R:K197	94.3192	10.51	No	No	0	0	7
17	R:R:K197	R:R:L201	94.075	5.64	No	No	0	7	8
18	L:L:L14	R:R:L201	93.8283	5.54	No	No	0	0	8
19	L:L:L14	R:R:M204	92.559	7.07	No	No	0	0	2
20	L:L:E15	R:R:M204	91.7687	4.06	No	No	0	0	2
21	L:L:E15	R:R:S31	91.2298	4.31	No	No	0	0	3
22	R:R:E34	R:R:V30	33.4499	9.98	No	No	0	3	4
23	R:R:E34	R:R:S31	90.6814	2.87	No	No	0	3	3
24	R:R:P90	R:R:V30	32.1638	8.84	No	No	0	3	4
25	R:R:L89	R:R:P90	31.7938	4.93	Yes	No	0	6	3
26	R:R:E34	R:R:K38	57.271	4.05	No	No	0	3	4
27	R:R:K38	R:R:Y88	47.38	4.78	No	Yes	3	4	4
28	R:R:L89	R:R:Y88	33.9408	3.52	Yes	Yes	3	6	4
29	R:R:L89	R:R:W91	62.3853	20.5	Yes	Yes	3	6	4
30	R:R:V95	R:R:W91	58.4385	6.13	Yes	Yes	3	4	4
31	R:R:C85	R:R:V95	53.481	3.42	No	Yes	0	9	4
32	R:R:C126	R:R:C85	52.4692	7.28	No	No	0	9	9
33	R:R:C126	R:R:V100	51.4549	5.12	No	No	0	9	7
34	R:R:L123	R:R:V100	50.4383	10.43	No	No	0	6	7
35	R:R:L123	R:R:R121	49.4192	9.72	No	No	0	6	6
36	R:R:P119	R:R:R121	48.3978	10.09	Yes	No	0	7	6
37	R:R:P119	R:R:R102	24.1193	7.21	Yes	Yes	4	7	8
38	R:R:C62	R:R:R102	16.6555	6.96	Yes	Yes	4	9	8
39	R:R:L118	R:R:P119	17.756	3.28	No	Yes	0	3	7
40	R:R:K113	R:R:L118	14.4917	5.64	No	No	0	4	3
41	R:R:K113	R:R:W120	12.2883	1.16	No	No	0	4	6
42	R:R:L183	R:R:W243	18.1248	3.42	Yes	Yes	2	9	9
43	R:R:E247	R:R:L183	47.6709	11.93	Yes	Yes	2	9	9
44	R:R:E247	R:R:L359	18.8852	7.95	Yes	Yes	2	9	9
45	R:R:L359	R:R:V398	14.5755	4.47	Yes	No	2	9	8
46	R:R:P358	R:R:V398	15.0557	7.07	No	No	0	9	8
47	R:R:L401	R:R:P358	13.2763	1.64	No	No	0	8	9
48	R:R:L401	R:R:M397	10.8837	1.41	No	No	0	8	7
49	R:R:E247	R:R:H180	26.8806	11.08	Yes	Yes	2	9	9
50	R:R:F184	R:R:H180	11.4657	3.39	Yes	Yes	2	8	9
51	R:R:H180	R:R:R176	17.0698	6.77	Yes	No	0	9	9
52	R:R:N177	R:R:R176	13.3433	3.62	No	No	0	9	9
53	R:R:L172	R:R:N177	12.4057	6.87	No	No	0	9	9
54	R:R:F187	R:R:L183	22.6344	8.53	Yes	Yes	0	8	9
55	L:L:H1	R:R:Q234	15.3898	3.71	Yes	No	0	0	7
56	R:R:Q234	R:R:W284	14.9132	12.05	No	Yes	0	7	8
57	R:R:K288	R:R:W284	39.072	12.76	Yes	Yes	1	8	8
58	R:R:K288	R:R:W297	37.9284	11.6	Yes	Yes	1	8	9
59	R:R:R299	R:R:W284	16.6291	5	Yes	Yes	1	4	8
60	L:L:H1	R:R:I309	18.5942	11.93	Yes	No	0	0	6
61	R:R:I309	R:R:W284	15.2581	32.88	No	Yes	0	6	8
62	R:R:W297	R:R:Y289	16.78	9.65	Yes	Yes	1	9	3
63	R:R:S223	R:R:Y289	10.7532	5.09	No	Yes	1	3	3
64	R:R:R227	R:R:W297	10.6778	5	Yes	Yes	1	8	9
65	R:R:I317	R:R:Y241	14.3767	3.63	No	Yes	2	7	7
66	R:R:L384	R:R:R376	10.1844	7.29	No	No	0	6	4
67	R:R:F367	R:R:L384	10.8825	10.96	No	No	0	7	6
68	R:R:E387	R:R:F367	11.6022	5.83	No	No	0	7	7
69	R:R:E364	R:R:E387	13.0751	5.07	Yes	No	0	7	7
70	R:R:I317	R:R:N320	15.7011	7.08	No	No	0	7	9
71	R:R:N320	R:R:T362	18.3583	5.85	No	No	0	9	6
72	R:R:F324	R:R:T362	13.9995	12.97	No	No	0	9	6
73	R:R:F324	R:R:I328	10.285	7.54	No	No	0	9	7
74	R:R:R190	R:R:Y241	15.8915	6.17	Yes	Yes	2	8	7
75	R:R:L183	R:R:S186	16.998	4.5	Yes	Yes	2	9	9
76	R:R:F187	R:R:N240	18.0457	21.75	Yes	Yes	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:H1	R:R:Q234	3.71	1	Yes	No	0	7	0	1
L:L:H1	R:R:R299	13.54	1	Yes	Yes	0	4	0	1
L:L:H1	R:R:W306	8.46	1	Yes	Yes	0	6	0	1
L:L:H1	R:R:I309	11.93	1	Yes	No	0	6	0	1
L:L:H1	R:R:R310	11.28	1	Yes	Yes	0	7	0	1
L:L:H1	R:R:I313	3.98	1	Yes	No	0	7	0	1
L:L:A2	R:R:Y241	4	0	No	Yes	0	7	0	1
L:L:E3	R:R:R190	3.49	0	Yes	Yes	0	8	0	1
L:L:E3	R:R:V194	7.13	0	Yes	No	0	7	0	1
L:L:E3	R:R:M233	6.77	0	Yes	No	0	6	0	1
L:L:E3	R:R:L388	10.6	0	Yes	No	0	7	0	1
L:L:T5	R:R:R299	6.47	1	No	Yes	0	4	0	1
L:L:T5	R:R:W306	4.85	1	No	Yes	0	6	0	1
L:L:F6	R:R:F381	4.29	0	Yes	No	0	3	0	1
L:L:F6	R:R:F385	11.79	0	Yes	No	0	5	0	1
L:L:F6	R:R:L388	3.65	0	Yes	No	0	7	0	1
L:L:T7	R:R:K197	10.51	0	No	No	0	7	0	1
L:L:S8	R:R:T298	4.8	0	No	No	0	5	0	1
L:L:V10	R:R:L142	4.47	0	No	No	0	3	0	1
L:L:S12	R:R:T298	6.4	0	No	No	0	5	0	1
L:L:Y13	R:R:E138	15.71	0	No	No	0	2	0	1
L:L:Y13	R:R:L142	3.52	0	No	No	0	3	0	1
L:L:L14	R:R:L201	5.54	0	No	No	0	8	0	1
L:L:L14	R:R:M204	7.07	0	No	No	0	2	0	1
L:L:E15	R:R:S31	4.31	0	No	No	0	3	0	1
L:L:E15	R:R:M204	4.06	0	No	No	0	2	0	1
L:L:A19	R:R:T35	3.36	0	No	No	0	5	0	1
L:L:K20	R:R:W91	6.96	3	No	Yes	0	4	0	1
L:L:K20	R:R:E128	5.4	3	No	No	0	2	0	1
L:L:F22	R:R:W39	10.02	3	Yes	Yes	0	5	0	1
L:L:F22	R:R:H212	9.05	3	Yes	No	0	3	0	1
L:L:I23	R:R:Y69	3.63	3	No	Yes	0	5	0	1
L:L:I23	R:R:L89	7.14	3	No	Yes	0	6	0	1
L:L:W25	R:R:Q211	12.05	3	Yes	No	0	3	0	1
L:L:W25	R:R:H212	15.87	3	Yes	No	0	3	0	1
L:L:L26	R:R:W39	7.97	3	Yes	Yes	0	5	0	1
L:L:L26	R:R:D68	8.14	3	Yes	No	0	5	0	1
L:L:L26	R:R:Y69	5.86	3	Yes	Yes	0	5	0	1
L:L:V27	R:R:Y69	18.93	0	No	Yes	0	5	0	1
R:R:E34	R:R:V30	9.98	0	No	No	3	4	2	2
R:R:T35	R:R:V30	3.17	0	No	No	5	4	1	2
R:R:P90	R:R:V30	8.84	0	No	No	3	4	2	2
R:R:S31	R:R:S33	4.89	0	No	No	3	5	1	2
R:R:E34	R:R:S31	2.87	0	No	No	3	3	2	1
R:R:R40	R:R:W39	5	0	No	Yes	3	5	2	1
R:R:R43	R:R:W39	10	0	No	Yes	5	5	2	1
R:R:D68	R:R:W39	11.17	3	No	Yes	5	5	1	1
R:R:W39	R:R:Y88	8.68	3	Yes	Yes	5	4	1	2
R:R:Q213	R:R:R40	9.35	0	No	No	4	3	2	2
R:R:F66	R:R:R43	8.55	0	Yes	No	7	5	2	2
R:R:D68	R:R:F66	4.78	3	No	Yes	5	7	1	2
R:R:P86	R:R:Y69	16.69	3	No	Yes	8	5	2	1
R:R:Y69	R:R:Y88	6.95	3	Yes	Yes	5	4	1	2
R:R:L89	R:R:Y69	5.86	3	Yes	Yes	6	5	1	1
R:R:P86	R:R:Y88	11.13	3	No	Yes	8	4	2	2
R:R:L89	R:R:Y88	3.52	3	Yes	Yes	6	4	1	2
R:R:L89	R:R:P90	4.93	3	Yes	No	6	3	1	2
R:R:L89	R:R:W91	20.5	3	Yes	Yes	6	4	1	1
R:R:N94	R:R:W91	5.65	3	No	Yes	4	4	2	1
R:R:V95	R:R:W91	6.13	3	Yes	Yes	4	4	2	1
R:R:E128	R:R:W91	17.45	3	No	Yes	2	4	1	1
R:R:N94	R:R:V95	7.39	3	No	Yes	4	4	2	2
R:R:K113	R:R:L118	5.64	0	No	No	4	3	2	1
R:R:L118	R:R:P119	3.28	0	No	Yes	3	7	1	2
R:R:E138	R:R:S136	7.19	5	No	Yes	2	1	1	2
R:R:E139	R:R:S136	4.31	5	Yes	Yes	2	1	1	2
R:R:E138	R:R:E139	7.61	5	No	Yes	2	2	1	1
R:R:E139	R:R:L142	5.3	5	Yes	No	2	3	1	1
R:R:E139	R:R:S143	2.87	5	Yes	No	2	4	1	2
R:R:F385	R:R:L141	8.53	0	No	No	5	5	1	2
R:R:F385	R:R:Y145	12.38	0	No	Yes	5	5	1	2
R:R:L388	R:R:Y145	3.52	0	No	Yes	7	5	1	2
R:R:R190	R:R:V237	3.92	2	Yes	No	8	6	1	2
R:R:N240	R:R:R190	13.26	2	Yes	Yes	9	8	2	1
R:R:R190	R:R:Y241	6.17	2	Yes	Yes	8	7	1	1
R:R:R190	R:R:T391	5.17	2	Yes	Yes	8	6	1	2
R:R:M233	R:R:S193	7.67	0	No	No	6	5	1	2
R:R:K197	R:R:L201	5.64	0	No	No	7	8	1	1
R:R:D215	R:R:M204	9.7	0	No	No	3	2	2	1
R:R:H212	R:R:Q211	6.18	3	No	No	3	3	1	1
R:R:Q211	R:R:Q213	3.84	3	No	No	3	4	1	2
R:R:Q234	R:R:W284	12.05	0	No	Yes	7	8	1	2
R:R:V237	R:R:Y241	6.31	2	No	Yes	6	7	2	1
R:R:N240	R:R:Y241	3.49	2	Yes	Yes	9	7	2	1
R:R:I317	R:R:Y241	3.63	2	No	Yes	7	7	2	1
R:R:E364	R:R:Y241	17.96	2	Yes	Yes	7	7	2	1
R:R:T391	R:R:Y241	6.24	2	Yes	Yes	6	7	2	1
R:R:I313	R:R:Y242	6.04	0	No	Yes	7	6	1	2
R:R:F280	R:R:I309	6.28	0	No	No	5	6	2	1
R:R:R299	R:R:W284	5	1	Yes	Yes	4	8	1	2
R:R:I309	R:R:W284	32.88	0	No	Yes	6	8	1	2
R:R:S301	R:R:T298	3.2	1	No	No	4	5	2	1
R:R:N302	R:R:R299	4.82	1	Yes	Yes	4	4	2	1
R:R:R299	R:R:W306	17.99	1	Yes	Yes	4	6	1	1
R:R:N302	R:R:S301	2.98	1	Yes	No	4	4	2	2
R:R:R310	R:R:W306	15.99	1	Yes	Yes	7	6	1	1
R:R:V370	R:R:W306	4.9	1	Yes	Yes	5	6	2	1
R:R:L314	R:R:R310	25.51	0	No	Yes	4	7	2	1
R:R:R310	R:R:V370	7.85	1	Yes	Yes	7	5	1	2
R:R:E364	R:R:I317	4.1	2	Yes	No	7	7	2	2
R:R:E364	R:R:T391	8.47	2	Yes	Yes	7	6	2	2
L:L:K28	R:R:L118	2.82	0	No	No	0	3	0	1
R:R:K202	R:R:Y205	2.39	0	No	No	4	3	2	1
L:L:L14	R:R:Y205	2.34	0	No	No	0	3	0	1
R:R:A92	R:R:L89	1.58	0	No	Yes	5	6	2	1
L:L:Q17	R:R:E139	1.27	0	No	Yes	0	2	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	5VAI_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.87
Number of Linked Nodes	372
Number of Links	428
Number of Hubs	56
Number of Links mediated by Hubs	201
Number of Communities	8
Number of Nodes involved in Communities	87
Number of Links involved in Communities	127

Path Summary
Number Of Nodes in MetaPath	77
Number Of Links MetaPath	76
Number of Shortest Paths	140523
Length Of Smallest Path	3
Average Path Length	23.7433
Length of Longest Path	52
Minimum Path Strength	1.215
Average Path Strength	7.18871
Maximum Path Strength	22.82
Minimum Path Correlation	0.7
Average Path Correlation	0.963776
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.85714
Average % Of Corr. Nodes	56.5908
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.5053
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell surface receptor signaling pathway • multicellular organismal process • system process • circulatory system process • regulation of blood pressure • positive regulation of blood pressure • regulation of biological quality • blood circulation • cell periphery • cellular anatomical structure • plasma membrane • membrane • protein binding • binding • signaling receptor binding • molecular transducer activity • molecular function activator activity • signaling receptor activity • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • G protein-coupled receptor binding • glucagon receptor binding • hormone activity • identical protein binding • monosaccharide metabolic process • positive regulation of biological process • gluconeogenesis • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • small molecule metabolic process • regulation of carbohydrate metabolic process • regulation of glucose metabolic process • positive regulation of cellular process • positive regulation of gluconeogenesis • regulation of biosynthetic process • carbohydrate metabolic process • small molecule biosynthetic process • carbohydrate biosynthetic process • hexose metabolic process • primary metabolic process • monosaccharide biosynthetic process • hexose biosynthetic process • positive regulation of glucose metabolic process • biosynthetic process • regulation of gluconeogenesis • metabolic process • positive regulation of carbohydrate metabolic process • regulation of carbohydrate biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • glucose metabolic process • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • intracellular signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • intracellular signaling cassette • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of biological process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • negative regulation of cellular process • apoptotic process • programmed cell death • cellular response to nitrogen compound • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular response to hormone stimulus • response to activity • protein kinase A signaling • negative regulation of execution phase of apoptosis • regulation of execution phase of apoptosis • execution phase of apoptosis • behavior • feeding behavior • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • positive regulation of establishment of protein localization • carbohydrate homeostasis • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • positive regulation of peptide hormone secretion • intracellular glucose homeostasis • cellular response to carbohydrate stimulus • chemical homeostasis • response to glucose • glucose homeostasis • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • homeostatic process • positive regulation of secretion by cell • positive regulation of protein transport • positive regulation of hormone secretion • response to monosaccharide • response to carbohydrate • positive regulation of secretion • cellular response to hexose stimulus • intracellular chemical homeostasis • cellular response to monosaccharide stimulus • positive regulation of peptide secretion • cellular response to glucose stimulus • positive regulation of protein secretion • response to hexose • cellular homeostasis • positive regulation of transport • regulation of insulin secretion involved in cellular response to glucose stimulus • regulation of calcium ion import • regulation of calcium ion transport • positive regulation of calcium ion transport • positive regulation of calcium ion import • regulation of monoatomic ion transport • calcium ion transport • metal ion transport • positive regulation of monoatomic ion transport • monoatomic ion transport • calcium ion import • monoatomic cation transport • regulation of metal ion transport • membrane-bounded organelle • intracellular anatomical structure • membrane-enclosed lumen • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle lumen • endoplasmic reticulum lumen • intracellular organelle • organelle lumen • organelle • endoplasmic reticulum • cytoplasm • extracellular region • vesicle lumen • intracellular vesicle • cytoplasmic vesicle lumen • secretory granule lumen • cytoplasmic vesicle • secretory granule • secretory vesicle • vesicle • extracellular space • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • trans-Golgi network • organelle membrane • cytoskeletal protein binding • spectrin binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • response to hypoxia • response to oxygen levels • response to abiotic stimulus • cell population proliferation • phospholipase C-activating G protein-coupled receptor signaling pathway • muscle cell apoptotic process • striated muscle cell apoptotic process • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	G1SGD4
Sequence	>5VAI_nogp_Chain_R T V S L S E T V Q K W R E Y R R Q C Q H F L T E A P P L A T G L F C N R T F D D Y A C W P D G A P G S F V N V S C P W Y L P W A S N V L Q G H V Y R F C T A E G H W L P K D N S S L P W R D L S E C E E S S P E E R L L S L Y I I Y T V G Y A L S F S A L V I A S A I L L G F R H L H C T R N Y I H L N L F A S F I L R A L S V F I K D A A L K W M Y S T A A Q Q H Q W D G L L S Y Q D S L G C R L V F L L M Q Y C V A A N Y Y W L L V E G A Y L Y T L L A F A V F S E Q R I F K L Y L S I G W G V P L L F V I P W G I V K Y L Y E D E G C W T R N S N M N Y W L I I R L P I L F A I G V N F L I F I R V I C I V V S K L K A N L M C K T D I K C R L A K S T L T L I P L L G T H E V I F A F V M D E H A R G T L R F V K L F T E L S F T S F Q G L M V A I L Y C F V N N E V Q M E F R K S W E R W R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839	chim(NtGi1-Gs)/β2/γ2	3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	9IVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	LSN3318839		3.22	2024-11-13	10.1016/j.apsb.2024.09.002
	8YW3	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-	Gs/β1/γ2	2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8YW3 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Retatrutide	-		2.68	2024-09-18	doi.org/10.1038/s41421-024-00700-0
	8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.54	2024-03-06	10.1038/s41421-024-00649-0
	8WG7 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.54	2024-03-06	10.1038/s41421-024-00649-0
	8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/β1/γ2	2.46	2023-11-08	10.1073/pnas.2303696120
	8JIS (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-		2.46	2023-11-08	10.1073/pnas.2303696120
	8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/β1/γ2	2.57	2023-09-06	10.1073/pnas.2303696120
	8JIR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-		2.57	2023-09-06	10.1073/pnas.2303696120
	8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/β1/γ2	2.85	2023-09-06	10.1073/pnas.2303696120
	8JIP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-		2.85	2023-09-06	10.1073/pnas.2303696120
	9IVG	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	chim(NtGi1-Gs)/β1/γ2	3	2024-11-27	10.1016/j.apsb.2024.09.002
	9IVG (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-		3	2024-11-27	10.1016/j.apsb.2024.09.002
	9J1P	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-	chim(NtGi1-Gs)/β1/γ2	2.99	2025-02-26	10.1021/jacs.4c12808
	9J1P (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	g1:Ox	-		2.99	2025-02-26	10.1021/jacs.4c12808
	7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/β1/γ2	3.09	2022-06-29	10.1073/pnas.2200155119
	7X8S (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-		3.09	2022-06-29	10.1073/pnas.2200155119
	7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/β1/γ2	2.61	2022-06-29	10.1073/pnas.2200155119
	7X8R (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-		2.61	2022-06-29	10.1073/pnas.2200155119
	7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
	7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2022-04-13	10.1073/pnas.2116506119
	7RGP (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		2.9	2022-04-13	10.1073/pnas.2116506119
	7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2022-04-13	10.1073/pnas.2116506119
	7RG9 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		3.2	2022-04-13	10.1073/pnas.2116506119
	7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/β1/γ2	3	2022-04-06	10.1038/s41467-022-28683-0
	7VBH (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-		3	2022-04-06	10.1038/s41467-022-28683-0
	7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/β1/γ2	3	2022-03-02	10.1038/s41467-022-28683-0
	7VBI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-		3	2022-03-02	10.1038/s41467-022-28683-0
	7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/β1/γ2	3.4	2022-03-02	10.1038/s41467-022-28683-0
	7FIM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-		3.4	2022-03-02	10.1038/s41467-022-28683-0
	7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/β1/γ2	3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLY (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-		3.3	2022-01-12	10.1038/s41467-021-27760-0
	7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/β1/γ2	3.7	2022-01-12	10.1038/s41467-021-27760-0
	7LLL (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-		3.7	2022-01-12	10.1038/s41467-021-27760-0
	7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/β1/γ2	2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S3I (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-		2.51	2022-01-05	10.1038/s41589-021-00945-w
	7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/β1/γ2	2.41	2022-01-05	10.1038/s41589-021-00945-w
	7S1M (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-		2.41	2022-01-05	10.1038/s41589-021-00945-w
	7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/β1/γ2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7RTB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-		2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
	7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	2.5	2021-08-11	10.1038/s41467-021-24058-z
	7EVM (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		2.5	2021-08-11	10.1038/s41467-021-24058-z
	7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/β1/γ2	3.3	2021-08-11	10.1038/s41467-021-24058-z
	7DUR (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738		3.3	2021-08-11	10.1038/s41467-021-24058-z
	7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI1 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/β1/γ2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7KI0 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-		2.5	2021-08-04	10.1016/j.celrep.2021.109374
	7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/β1/γ2	2.5	2021-07-14	10.1038/s41467-021-24058-z
	7DUQ (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738		2.5	2021-07-14	10.1038/s41467-021-24058-z
	7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/β1/γ2	2.9	2021-07-07	10.1038/s41467-021-24058-z
	7E14 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738		2.9	2021-07-07	10.1038/s41467-021-24058-z
	7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
	7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
	7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.9	2021-01-20	10.1016/j.str.2021.04.008
	7LCI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.9	2021-01-20	10.1016/j.str.2021.04.008
	6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/β1/γ2	3.1	2020-11-18	10.1073/pnas.2014879117
	6XOX (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-		3.1	2020-11-18	10.1073/pnas.2014879117
	6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/β1/γ2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X1A (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-		2.5	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X19 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/β1/γ2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	6X18 (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-		2.1	2020-09-09	10.1016/j.molcel.2020.09.020
	7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/β1/γ2	4.2	2020-08-26	10.1038/s41422-020-0384-8
	7C2E (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-		4.2	2020-08-26	10.1038/s41422-020-0384-8
	6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/β1/γ2	3.3	2020-07-22	10.1038/s41589-020-0589-7
	6VCB (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440		3.3	2020-07-22	10.1038/s41589-020-0589-7
	6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
	6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/β1/γ2	3	2020-01-08	10.1038/s41586-019-1902-z
	6ORV (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2		3	2020-01-08	10.1038/s41586-019-1902-z
	6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
	6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
	6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/β1/γ2	3.3	2018-02-21	10.1038/nature25773
	6B3J (No Gprot)	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-		3.3	2018-02-21	10.1038/nature25773
	5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
	5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
	5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/β1/γ2	4.1	2017-05-24	10.1038/nature22394
	5VAI (No Gprot)	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-		4.1	2017-05-24	10.1038/nature22394
	5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378

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