psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:N14	A:A:Q12	9.24	No	No	0	3	2
2	A:A:K17	A:A:R13	4.95	No	No	0	4	4
3	A:A:E15	A:A:E16	5.07	No	No	0	6	4
4	A:A:E16	A:A:K17	12.15	No	No	0	4	4
5	A:A:N23	A:A:Q19	6.6	No	Yes	3	7	4
6	A:A:Q19	B:B:T86	5.67	Yes	Yes	3	4	6
7	A:A:Q19	B:B:N88	11.88	Yes	Yes	3	4	7
8	A:A:R20	B:B:N88	3.62	No	Yes	0	3	7
9	A:A:E21	A:A:K25	8.1	No	No	0	2	5
10	A:A:N23	B:B:N88	16.35	No	Yes	3	7	7
11	A:A:K25	A:A:K28	4.31	No	No	0	5	4
12	A:A:I26	B:B:K89	5.82	No	Yes	0	9	9
13	A:A:E27	A:A:L30	5.3	No	No	0	6	5
14	A:A:E27	B:B:K89	5.4	No	Yes	0	6	9
15	A:A:D33	B:B:K78	4.15	No	No	0	5	8
16	A:A:K34	A:A:R38	3.71	No	No	0	4	4
17	A:A:Q35	R:R:K319	6.78	No	No	0	3	6
18	A:A:R42	A:A:Y37	13.38	No	No	0	9	4
19	A:A:Y37	B:B:L55	4.69	No	No	0	4	6
20	A:A:Y37	B:B:A56	4	No	No	0	4	7
21	A:A:R38	R:R:K318	3.71	No	No	0	4	5
22	A:A:N218	A:A:T40	4.39	Yes	No	14	4	7
23	A:A:H220	A:A:T40	5.48	Yes	No	14	7	7
24	A:A:F219	A:A:H41	10.18	Yes	No	0	8	6
25	A:A:H41	A:A:T242	4.11	No	No	0	6	8
26	A:A:H41	A:A:I383	3.98	No	No	0	6	8
27	A:A:D240	A:A:R42	4.76	No	No	0	6	9
28	A:A:R42	A:A:V241	3.92	No	No	0	9	9
29	A:A:F219	A:A:L43	4.87	Yes	No	0	8	7
30	A:A:L43	A:A:M221	4.24	No	No	0	7	8
31	A:A:I245	A:A:L43	4.28	No	No	0	7	7
32	A:A:L44	A:A:L46	6.92	No	No	2	9	8
33	A:A:F238	A:A:L44	19.49	Yes	No	2	9	9
34	A:A:K53	A:A:L45	4.23	No	No	20	9	8
35	A:A:L45	A:A:M221	7.07	No	No	0	8	8
36	A:A:D223	A:A:L45	5.43	Yes	No	20	9	8
37	A:A:G47	A:A:S51	3.71	No	No	0	9	9
38	A:A:G47	A:A:K53	5.23	No	No	0	9	9
39	A:A:D49	A:A:N50	9.42	No	No	21	8	9
40	A:A:D49	A:A:R265	5.96	No	No	21	8	9
41	A:A:D249	A:A:N50	4.04	No	No	0	8	9
42	A:A:N50	A:A:R265	15.67	No	No	21	9	9
43	A:A:G52	A:A:T55	5.46	No	No	0	9	9
44	A:A:D223	A:A:K53	6.91	Yes	No	20	9	9
45	A:A:I56	A:A:N292	9.91	No	Yes	0	7	9
46	A:A:T210	A:A:V57	7.93	No	No	0	7	7
47	A:A:K58	A:A:Q59	8.14	No	No	0	9	9
48	A:A:F212	A:A:M60	7.46	No	No	0	9	9
49	A:A:I207	A:A:V224	4.61	No	No	0	9	9
50	A:A:D223	A:A:F208	4.78	Yes	No	0	9	5
51	A:A:E209	A:A:K211	8.1	No	No	0	9	4
52	A:A:K211	A:A:N218	6.99	No	Yes	14	4	4
53	A:A:H220	A:A:K211	17.03	Yes	No	14	7	4
54	A:A:F212	A:A:F219	13.93	No	Yes	0	9	8
55	A:A:N218	A:A:Q213	5.28	Yes	No	0	4	3
56	A:A:D215	A:A:V214	4.38	No	No	15	5	6
57	A:A:F219	A:A:V214	3.93	Yes	No	0	8	6
58	A:A:F376	A:A:V214	3.93	Yes	No	15	8	6
59	A:A:D215	A:A:R373	9.53	No	Yes	15	5	5
60	A:A:D215	A:A:F376	4.78	No	Yes	15	5	8
61	A:A:F219	A:A:V217	3.93	Yes	No	0	8	5
62	A:A:V217	R:R:F314	3.93	No	No	0	5	7
63	A:A:H220	A:A:N218	6.38	Yes	Yes	14	7	4
64	A:A:C379	A:A:F219	4.19	No	Yes	0	8	8
65	A:A:F222	A:A:H220	7.92	No	Yes	0	7	7
66	A:A:F222	B:B:W99	14.03	No	Yes	0	7	9
67	A:A:Q227	A:A:V224	5.73	No	No	0	9	9
68	A:A:V224	A:A:W234	12.26	No	Yes	0	9	9
69	A:A:Q227	B:B:N119	7.92	No	No	0	9	9
70	A:A:E230	A:A:R228	15.12	No	No	0	9	9
71	A:A:R228	B:B:T164	3.88	No	No	0	9	6
72	A:A:E230	A:A:R232	9.3	No	No	0	9	8
73	A:A:R231	A:A:W234	9	No	Yes	0	9	9
74	A:A:L272	A:A:R231	6.07	No	No	0	8	9
75	A:A:R232	B:B:C204	4.18	No	Yes	6	8	7
76	A:A:R232	B:B:D228	5.96	No	Yes	6	8	9
77	A:A:K233	B:B:M188	10.08	Yes	Yes	6	9	8
78	A:A:K233	B:B:C204	8.08	Yes	Yes	6	9	7
79	A:A:K233	B:B:D228	11.06	Yes	Yes	6	9	9
80	A:A:K233	B:B:N230	4.2	Yes	No	0	9	9
81	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
82	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
83	A:A:W234	B:B:Y145	7.72	Yes	Yes	0	9	8
84	A:A:Q236	A:A:W281	10.95	No	Yes	0	8	5
85	A:A:C237	A:A:F238	9.78	No	Yes	2	8	9
86	A:A:C237	B:B:Q75	4.58	No	No	2	8	9
87	A:A:C237	B:B:W99	6.53	No	Yes	2	8	9
88	A:A:F238	A:A:V241	3.93	Yes	No	0	9	9
89	A:A:F238	B:B:W99	12.03	Yes	Yes	2	9	9
90	A:A:N239	B:B:K57	8.39	No	Yes	2	8	9
91	A:A:N239	B:B:W332	9.04	No	Yes	2	8	9
92	A:A:D240	B:B:K57	5.53	No	Yes	0	6	9
93	A:A:D240	B:B:W99	4.47	No	Yes	0	6	9
94	A:A:I244	A:A:I285	4.42	No	No	0	8	7
95	A:A:I245	A:A:I288	4.42	No	Yes	0	7	9
96	A:A:F246	A:A:L272	7.31	No	No	0	9	8
97	A:A:F246	A:A:F273	4.29	No	Yes	9	9	9
98	A:A:F246	A:A:L289	3.65	No	Yes	9	9	9
99	A:A:N292	A:A:V247	4.43	Yes	No	0	9	7
100	A:A:L291	A:A:V248	4.47	No	No	0	8	7
101	A:A:F345	A:A:V248	5.24	Yes	No	0	8	7
102	A:A:D249	A:A:K293	8.3	No	Yes	0	8	9
103	A:A:L291	A:A:S250	4.5	No	Yes	10	8	6
104	A:A:Q294	A:A:S250	10.11	Yes	Yes	10	6	6
105	A:A:L297	A:A:S250	6.01	No	Yes	10	8	6
106	A:A:K300	A:A:S251	4.59	No	No	0	9	9
107	A:A:D252	A:A:N264	4.04	No	No	0	8	9
108	A:A:D252	A:A:R265	7.15	No	No	0	8	9
109	A:A:L297	A:A:Y253	3.52	No	Yes	10	8	8
110	A:A:K300	A:A:Y253	19.11	No	Yes	10	9	8
111	A:A:S306	A:A:Y253	6.36	No	Yes	10	7	8
112	A:A:I308	A:A:Y253	9.67	No	Yes	0	7	8
113	A:A:Y253	A:A:Y311	5.96	Yes	No	0	8	6
114	A:A:N264	A:A:Y311	10.47	No	No	0	9	6
115	A:A:E268	A:A:Q267	3.82	No	No	0	9	4
116	A:A:N271	A:A:Q267	11.88	No	No	0	5	4
117	A:A:E344	A:A:L270	7.95	No	No	0	5	6
118	A:A:F345	A:A:L270	14.61	Yes	No	0	8	6
119	A:A:F273	A:A:W277	6.01	Yes	Yes	9	9	6
120	A:A:F273	A:A:V287	6.55	Yes	No	9	9	6
121	A:A:F273	A:A:L289	7.31	Yes	Yes	9	9	9
122	A:A:F273	A:A:F345	6.43	Yes	Yes	9	9	8
123	A:A:F273	A:A:I348	6.28	Yes	No	0	9	4
124	A:A:C359	A:A:F273	4.19	No	Yes	9	5	9
125	A:A:K274	A:A:N278	4.2	No	No	0	5	8
126	A:A:I348	A:A:K274	4.36	No	No	0	4	5
127	A:A:V287	A:A:W277	3.68	No	Yes	9	6	6
128	A:A:S349	A:A:W277	6.18	No	Yes	0	7	6
129	A:A:G353	A:A:W277	5.63	No	Yes	0	4	6
130	A:A:H357	A:A:W277	29.62	No	Yes	0	7	6
131	A:A:N278	A:A:S352	8.94	No	No	0	8	5
132	A:A:L282	A:A:N279	12.36	Yes	No	0	9	8
133	A:A:R280	A:A:W281	15.99	Yes	Yes	2	5	5
134	A:A:R280	B:B:C271	4.18	Yes	No	2	5	5
135	A:A:R280	B:B:D290	11.91	Yes	Yes	2	5	6
136	A:A:W281	B:B:D290	5.58	Yes	Yes	2	5	6
137	A:A:W281	B:B:R314	8	Yes	Yes	2	5	8
138	A:A:W281	B:B:W332	12.18	Yes	Yes	2	5	9
139	A:A:I382	A:A:S286	7.74	No	No	0	6	8
140	A:A:I288	A:A:Y360	3.63	Yes	Yes	22	9	8
141	A:A:I288	A:A:I375	5.89	Yes	No	0	9	9
142	A:A:D378	A:A:I288	7	No	Yes	22	7	9
143	A:A:F345	A:A:L289	4.87	Yes	Yes	9	8	9
144	A:A:C359	A:A:L289	4.76	No	Yes	9	5	9
145	A:A:F290	A:A:T364	5.19	No	Yes	23	9	9
146	A:A:F290	A:A:N371	10.87	No	No	23	9	9
147	A:A:L291	A:A:Q294	6.65	No	Yes	10	8	6
148	A:A:K293	A:A:N292	4.2	Yes	Yes	0	9	9
149	A:A:N292	A:A:T364	5.85	Yes	Yes	0	9	9
150	A:A:K293	A:A:L296	7.05	Yes	No	0	9	6
151	A:A:L297	A:A:Q294	6.65	No	Yes	10	8	6
152	A:A:K338	A:A:Q294	6.78	No	Yes	0	5	6
153	A:A:D295	A:A:L296	6.79	No	No	0	9	6
154	A:A:C365	A:A:D295	6.22	No	No	0	8	9
155	A:A:K300	A:A:S306	7.65	No	No	10	9	7
156	A:A:R333	A:A:V301	6.54	No	No	0	5	7
157	A:A:G304	A:A:R333	4.5	No	No	0	5	5
158	A:A:F315	A:A:I308	8.79	Yes	No	0	6	7
159	A:A:E309	A:A:F315	5.83	No	Yes	0	4	6
160	A:A:A316	A:A:E309	6.03	No	No	0	2	4
161	A:A:D310	A:A:Y311	5.75	No	No	0	3	6
162	A:A:F312	A:A:F340	5.36	No	No	0	8	7
163	A:A:F315	A:A:R336	10.69	Yes	No	0	6	5
164	A:A:F315	A:A:F340	12.86	Yes	No	0	6	7
165	A:A:A316	A:A:R317	4.15	No	No	0	2	2
166	A:A:P321	A:A:Y318	4.17	Yes	No	0	5	6
167	A:A:F340	A:A:Y318	12.38	No	No	0	7	6
168	A:A:D343	A:A:Y318	9.2	No	No	0	3	6
169	A:A:P321	A:A:T320	5.25	Yes	No	0	5	1
170	A:A:P321	A:A:Y339	9.74	Yes	Yes	0	5	3
171	A:A:D323	A:A:E322	9.09	No	No	0	4	1
172	A:A:A324	A:A:Y339	5.34	No	Yes	0	3	3
173	A:A:E330	A:A:P326	9.43	No	No	0	3	1
174	A:A:E327	A:A:E330	5.07	No	No	0	4	3
175	A:A:E330	A:A:T335	14.11	No	No	0	3	4
176	A:A:D331	A:A:P332	9.66	No	No	0	4	1
177	A:A:D331	A:A:R333	4.76	No	No	0	4	5
178	A:A:T335	A:A:Y339	4.99	No	Yes	0	4	3
179	A:A:K338	A:A:Y339	5.97	No	Yes	0	5	3
180	A:A:R342	A:A:Y339	4.12	No	Yes	0	4	3
181	A:A:F363	A:A:R342	4.28	No	No	0	5	4
182	A:A:E344	A:A:R347	12.79	No	No	0	5	4
183	A:A:L346	A:A:P361	8.21	No	No	0	4	5
184	A:A:G355	A:A:Y358	5.79	No	No	0	2	4
185	A:A:R385	A:A:Y358	11.32	No	No	0	5	4
186	A:A:D378	A:A:Y360	11.49	No	Yes	22	7	8
187	A:A:D381	A:A:Y360	12.64	No	Yes	0	8	8
188	A:A:I382	A:A:Y360	4.84	No	Yes	0	6	8
189	A:A:H362	A:A:R374	23.7	No	No	0	9	4
190	A:A:D378	A:A:H362	13.87	No	No	0	7	9
191	A:A:F363	A:A:R374	13.9	No	No	0	5	4
192	A:A:D368	A:A:T364	5.78	No	Yes	0	9	9
193	A:A:N371	A:A:T364	8.77	No	Yes	23	9	9
194	A:A:C365	A:A:D368	7.78	No	No	0	8	9
195	A:A:E370	A:A:R373	6.98	No	Yes	0	4	5
196	A:A:N371	A:A:R374	6.03	No	No	0	9	4
197	A:A:F376	A:A:R373	7.48	Yes	Yes	15	8	5
198	A:A:N377	A:A:R373	3.62	No	Yes	0	4	5
199	A:A:F376	A:A:R380	5.34	Yes	Yes	0	8	7
200	A:A:N377	A:A:R380	3.62	No	Yes	0	4	7
201	A:A:Q384	A:A:R380	4.67	No	Yes	0	6	7
202	A:A:R380	R:R:A313	6.91	Yes	No	0	7	7
203	A:A:D381	A:A:R385	11.91	No	No	0	8	5
204	A:A:D381	R:R:K388	5.53	No	No	0	8	9
205	A:A:Q384	R:R:K388	6.78	No	No	0	6	9
206	A:A:L394	A:A:R385	3.64	No	No	0	8	5
207	A:A:H387	A:A:Q390	3.71	No	No	0	8	4
208	A:A:H387	R:R:L309	21.86	No	Yes	12	8	8
209	A:A:H387	R:R:E317	6.15	No	Yes	12	8	6
210	A:A:L388	A:A:L394	4.15	No	No	0	8	8
211	A:A:L388	R:R:I310	5.71	No	No	0	8	8
212	A:A:Q390	R:R:R219	10.51	No	Yes	0	4	9
213	A:A:Y391	R:R:R219	5.14	No	Yes	0	4	9
214	A:A:Y391	R:R:L306	9.38	No	No	0	4	9
215	A:A:E392	R:R:N463	3.94	No	Yes	0	6	9
216	A:A:L393	R:R:L385	4.15	No	No	24	8	8
217	A:A:L393	R:R:S409	4.5	No	No	24	8	9
218	B:B:E3	B:B:L7	9.28	No	No	0	5	8
219	B:B:Q6	B:B:Q9	5.12	No	No	0	1	3
220	B:B:E10	G:G:V16	4.28	No	No	0	8	7
221	B:B:L14	G:G:L19	5.54	No	Yes	0	8	9
222	B:B:D20	B:B:Q17	3.92	No	No	0	2	4
223	B:B:I18	B:B:R22	7.52	Yes	Yes	0	7	6
224	B:B:I18	G:G:E22	5.47	Yes	No	0	7	9
225	B:B:A21	G:G:R27	5.53	No	Yes	0	4	8
226	B:B:D258	B:B:R22	10.72	Yes	Yes	1	7	6
227	B:B:Q259	B:B:R22	4.67	Yes	Yes	0	6	6
228	B:B:R22	G:G:R27	6.4	Yes	Yes	1	6	8
229	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
230	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
231	B:B:D27	G:G:K29	11.06	No	No	0	8	4
232	B:B:S31	B:B:T29	6.4	No	No	0	1	3
233	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
234	B:B:I33	B:B:L30	4.28	No	Yes	0	3	5
235	B:B:L30	B:B:M262	9.9	Yes	No	0	5	4
236	B:B:L30	G:G:A34	4.73	Yes	No	0	5	6
237	B:B:N35	B:B:N36	4.09	No	No	0	1	1
238	B:B:I37	B:B:N36	5.66	Yes	No	0	2	1
239	B:B:I37	B:B:R283	3.76	Yes	No	0	2	9
240	B:B:I37	B:B:K301	8.72	Yes	Yes	0	2	5
241	B:B:D38	B:B:P39	8.05	No	No	0	1	1
242	B:B:K301	B:B:P39	5.02	Yes	No	0	5	1
243	B:B:V40	G:G:L51	7.45	No	No	0	3	6
244	B:B:I43	B:B:V296	4.61	No	Yes	0	3	5
245	B:B:L308	B:B:M45	7.07	No	No	25	7	4
246	B:B:M45	B:B:W339	5.82	No	Yes	25	4	9
247	B:B:R46	B:B:R48	9.6	No	No	0	5	7
248	B:B:T47	B:B:T50	6.28	No	No	0	3	3
249	B:B:N340	B:B:R48	20.49	No	No	0	9	7
250	B:B:R49	G:G:F61	8.55	No	Yes	0	7	8
251	B:B:R52	B:B:T50	5.17	No	No	0	7	3
252	B:B:K337	B:B:T50	16.52	Yes	No	0	6	3
253	B:B:L51	B:B:L70	4.15	No	No	11	9	5
254	B:B:L51	B:B:W82	15.94	No	Yes	11	9	9
255	B:B:L336	B:B:L51	9.69	No	No	0	7	9
256	B:B:F335	B:B:R52	10.69	No	No	0	4	7
257	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
258	B:B:H54	B:B:S72	5.58	Yes	No	11	9	9
259	B:B:H54	B:B:S74	11.16	Yes	No	0	9	9
260	B:B:H54	B:B:I80	9.28	Yes	No	11	9	8
261	B:B:H54	B:B:W82	9.52	Yes	Yes	11	9	9
262	B:B:D76	B:B:L55	5.43	Yes	No	0	9	6
263	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
264	B:B:K57	B:B:Y59	5.97	Yes	Yes	2	9	8
265	B:B:K57	B:B:Q75	9.49	Yes	No	2	9	9
266	B:B:K57	B:B:W332	11.6	Yes	Yes	2	9	9
267	B:B:G330	B:B:I58	3.53	No	No	0	5	9
268	B:B:I58	B:B:L336	5.71	No	No	0	9	7
269	B:B:Q75	B:B:Y59	27.05	No	Yes	2	9	8
270	B:B:M101	B:B:Y59	5.99	Yes	Yes	0	9	8
271	B:B:S316	B:B:Y59	3.82	No	Yes	2	9	8
272	B:B:W332	B:B:Y59	5.79	Yes	Yes	2	9	8
273	B:B:M61	B:B:W63	5.82	No	Yes	0	6	7
274	B:B:C317	B:B:M61	4.86	No	No	0	7	6
275	B:B:H62	B:B:R150	14.67	No	No	0	6	6
276	B:B:L70	B:B:W63	11.39	No	Yes	0	5	7
277	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
278	B:B:T321	B:B:W63	12.13	No	Yes	0	7	7
279	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
280	B:B:G64	B:B:Y105	5.79	No	Yes	0	5	6
281	B:B:D66	B:B:R68	4.76	No	Yes	3	8	5
282	B:B:D66	B:B:L69	5.43	No	Yes	3	8	5
283	B:B:S67	B:B:T321	4.8	No	No	16	5	7
284	B:B:D322	B:B:S67	5.89	No	No	16	1	5
285	B:B:D323	B:B:S67	10.31	Yes	No	16	7	5
286	B:B:L69	B:B:R68	3.64	Yes	Yes	3	5	5
287	B:B:D83	B:B:R68	4.76	Yes	Yes	3	8	5
288	B:B:R68	B:B:Y85	18.52	Yes	No	3	5	4
289	B:B:R68	B:B:T86	5.17	Yes	Yes	3	5	6
290	B:B:D83	B:B:L69	5.43	Yes	Yes	3	8	5
291	B:B:L69	B:B:Y105	4.69	Yes	Yes	0	5	6
292	B:B:L70	B:B:W82	5.69	No	Yes	11	5	9
293	B:B:L79	B:B:V71	4.47	No	Yes	0	7	8
294	B:B:I81	B:B:V71	4.61	No	Yes	0	7	8
295	B:B:C103	B:B:V71	5.12	No	Yes	0	8	8
296	B:B:V71	B:B:Y105	5.05	Yes	Yes	0	8	6
297	B:B:V112	B:B:V71	4.81	No	Yes	0	8	8
298	B:B:S72	B:B:W82	3.71	No	Yes	11	9	9
299	B:B:L336	B:B:S72	7.51	No	No	0	7	9
300	B:B:A73	B:B:V100	5.09	No	No	0	9	9
301	B:B:A73	B:B:C103	3.61	No	No	0	9	8
302	B:B:D76	B:B:S74	10.31	Yes	No	0	9	9
303	B:B:D76	B:B:K78	8.3	Yes	No	0	9	8
304	B:B:K78	B:B:P94	5.02	No	No	0	8	5
305	B:B:I93	B:B:L79	5.71	No	No	0	7	7
306	B:B:L79	B:B:L95	4.15	No	Yes	0	7	8
307	B:B:I80	B:B:W82	10.57	No	Yes	11	8	9
308	B:B:I80	B:B:K89	5.82	No	Yes	11	8	9
309	B:B:K89	B:B:W82	6.96	Yes	Yes	11	9	9
310	B:B:D83	B:B:T86	5.78	Yes	Yes	3	8	6
311	B:B:D83	B:B:V90	5.84	Yes	No	0	8	5
312	B:B:S84	G:G:F61	7.93	No	Yes	0	5	8
313	B:B:Y85	G:G:P60	8.34	No	No	3	4	9
314	B:B:Y85	G:G:F61	9.28	No	Yes	3	4	8
315	B:B:N88	B:B:T86	7.31	Yes	Yes	3	7	6
316	B:B:H91	B:B:V133	5.54	No	No	0	5	4
317	B:B:I93	B:B:Y124	6.04	No	Yes	0	7	6
318	B:B:I93	B:B:V133	6.14	No	No	0	7	4
319	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
320	B:B:C114	B:B:L95	4.76	No	Yes	13	8	8
321	B:B:L95	B:B:Y124	7.03	Yes	Yes	13	8	6
322	B:B:D118	B:B:S97	7.36	No	No	0	9	8
323	B:B:L117	B:B:M101	4.24	No	Yes	0	9	9
324	B:B:M101	B:B:Y145	3.59	Yes	Yes	0	9	8
325	B:B:A104	B:B:R150	4.15	No	No	0	7	6
326	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
327	B:B:L126	B:B:Y105	3.52	No	Yes	0	5	6
328	B:B:A106	B:B:F151	4.16	No	Yes	0	6	9
329	B:B:N110	B:B:S108	8.94	Yes	No	17	4	6
330	B:B:D154	B:B:S108	5.89	No	No	17	6	6
331	B:B:N110	B:B:Y111	6.98	Yes	Yes	17	4	4
332	B:B:K127	B:B:N110	11.19	No	Yes	0	4	4
333	B:B:D154	B:B:N110	6.73	No	Yes	17	6	4
334	B:B:I123	B:B:Y111	6.04	Yes	Yes	0	6	4
335	B:B:N125	B:B:Y111	8.14	No	Yes	0	4	4
336	B:B:D154	B:B:Y111	14.94	No	Yes	17	6	4
337	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
338	B:B:C114	B:B:Y124	4.03	No	Yes	13	8	6
339	B:B:D118	B:B:I120	11.2	No	No	0	9	6
340	B:B:E138	B:B:I120	12.3	No	No	0	6	6
341	B:B:C121	B:B:C149	7.28	No	No	7	8	8
342	B:B:S122	B:B:Y124	10.17	No	Yes	13	8	6
343	B:B:S122	B:B:V135	6.46	No	Yes	13	8	4
344	B:B:F151	B:B:I123	6.28	Yes	Yes	0	9	6
345	B:B:V135	B:B:Y124	6.31	Yes	Yes	13	4	6
346	B:B:N125	B:B:T128	5.85	No	No	0	4	3
347	B:B:E130	B:B:T128	8.47	Yes	No	0	3	3
348	B:B:E130	B:B:R129	4.65	Yes	No	0	3	3
349	B:B:E130	B:B:N132	5.26	Yes	No	26	3	3
350	B:B:E130	B:B:R134	19.77	Yes	No	26	3	3
351	B:B:N132	B:B:R134	8.44	No	No	26	3	3
352	B:B:E138	B:B:V135	5.7	No	Yes	0	6	4
353	B:B:L139	B:B:W169	11.39	No	Yes	0	9	8
354	B:B:H142	B:B:L146	10.29	Yes	No	0	9	7
355	B:B:H142	B:B:T159	6.85	Yes	Yes	7	9	9
356	B:B:H142	B:B:S161	9.76	Yes	No	7	9	9
357	B:B:D163	B:B:H142	6.3	Yes	Yes	7	9	9
358	B:B:H142	B:B:W169	10.58	Yes	Yes	7	9	8
359	B:B:D163	B:B:T143	8.67	Yes	No	0	9	5
360	B:B:G162	B:B:Y145	8.69	No	Yes	0	9	8
361	B:B:D186	B:B:Y145	9.2	No	Yes	6	9	8
362	B:B:M188	B:B:Y145	4.79	Yes	Yes	6	8	8
363	B:B:S147	B:B:S160	4.89	No	No	0	9	6
364	B:B:C148	B:B:R150	6.96	No	No	0	6	6
365	B:B:C148	B:B:L190	6.35	No	No	0	6	5
366	B:B:F151	B:B:I157	10.05	Yes	No	0	9	7
367	B:B:L152	B:B:Q156	5.32	Yes	No	0	3	5
368	B:B:L152	B:B:L192	4.15	Yes	No	0	3	5
369	B:B:L152	B:B:V213	4.47	Yes	No	0	3	4
370	B:B:D153	B:B:Q156	3.92	No	No	0	5	5
371	B:B:D170	B:B:N155	4.04	No	No	0	9	3
372	B:B:I171	B:B:N155	4.25	Yes	No	0	6	3
373	B:B:L168	B:B:Q156	3.99	No	No	0	6	5
374	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
375	B:B:L190	B:B:V158	4.47	No	No	0	5	5
376	B:B:L192	B:B:V158	4.47	No	No	0	5	5
377	B:B:F199	B:B:V158	6.55	Yes	No	0	9	5
378	B:B:T159	B:B:W169	6.06	Yes	Yes	7	9	8
379	B:B:S160	B:B:V187	4.85	No	No	0	6	9
380	B:B:L190	B:B:S160	6.01	No	No	0	5	6
381	B:B:G162	B:B:S161	3.71	No	No	0	9	9
382	B:B:D163	B:B:S161	8.83	Yes	No	7	9	9
383	B:B:D163	B:B:T165	13.01	Yes	No	0	9	7
384	B:B:C166	B:B:F180	5.59	No	Yes	4	8	7
385	B:B:C166	B:B:F199	4.19	No	Yes	4	8	9
386	B:B:A167	B:B:W169	3.89	No	Yes	7	4	8
387	B:B:A167	B:B:Q176	4.55	No	No	7	4	4
388	B:B:L168	B:B:T177	7.37	No	No	0	6	4
389	B:B:Q176	B:B:W169	12.05	No	Yes	7	4	8
390	B:B:D170	B:B:T173	5.78	No	No	0	9	5
391	B:B:Q175	B:B:T173	15.59	No	No	0	4	5
392	B:B:Q176	B:B:T179	5.67	No	No	0	4	4
393	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
394	B:B:F180	B:B:F199	9.65	Yes	Yes	4	7	9
395	B:B:F180	B:B:W211	14.03	Yes	Yes	4	7	8
396	B:B:H183	B:B:V187	4.15	Yes	No	4	9	9
397	B:B:H183	B:B:S201	4.18	Yes	No	4	9	9
398	B:B:A203	B:B:H183	7.32	No	Yes	4	8	9
399	B:B:D205	B:B:H183	7.56	Yes	Yes	4	9	9
400	B:B:H183	B:B:K209	13.1	Yes	Yes	4	9	6
401	B:B:H183	B:B:W211	7.41	Yes	Yes	4	9	8
402	B:B:D205	B:B:T184	8.67	Yes	No	0	9	3
403	B:B:D186	B:B:M188	5.54	No	Yes	6	9	8
404	B:B:C204	B:B:D186	6.22	Yes	No	6	7	9
405	B:B:S201	B:B:V187	6.46	No	No	4	9	9
406	B:B:C204	B:B:M188	4.86	Yes	Yes	6	7	8
407	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
408	B:B:I232	B:B:S191	4.64	Yes	No	0	8	8
409	B:B:F234	B:B:S191	13.21	No	No	0	5	8
410	B:B:G238	B:B:P194	4.06	No	No	0	7	4
411	B:B:D195	B:B:R197	5.96	No	Yes	0	5	5
412	B:B:L198	B:B:R197	6.07	No	Yes	27	3	5
413	B:B:D212	B:B:R197	7.15	Yes	Yes	27	9	5
414	B:B:R197	B:B:R214	11.73	Yes	No	0	5	9
415	B:B:D212	B:B:L198	6.79	Yes	No	27	9	3
416	B:B:F199	B:B:W211	10.02	Yes	Yes	4	9	8
417	B:B:I232	B:B:V200	4.61	Yes	No	1	8	6
418	B:B:F234	B:B:V200	9.18	No	No	1	5	6
419	B:B:F241	B:B:V200	7.87	Yes	No	1	6	6
420	B:B:S201	B:B:W211	3.71	No	Yes	4	9	8
421	B:B:G202	B:B:I229	7.05	No	No	0	6	7
422	B:B:A203	B:B:D205	4.63	No	Yes	4	8	9
423	B:B:C204	B:B:D228	7.78	Yes	Yes	6	7	9
424	B:B:D205	B:B:S207	8.83	Yes	No	0	9	5
425	B:B:S207	B:B:T223	4.8	No	No	0	5	2
426	B:B:K209	B:B:W211	6.96	Yes	Yes	4	6	8
427	B:B:C218	B:B:K209	6.47	No	Yes	4	5	6
428	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
429	B:B:L210	B:B:R219	4.86	No	No	0	5	5
430	B:B:L210	B:B:Q220	6.65	No	Yes	0	5	7
431	B:B:C218	B:B:W211	5.22	No	Yes	4	5	8
432	B:B:D212	B:B:E215	11.69	Yes	No	0	9	3
433	B:B:D212	B:B:R219	13.1	Yes	No	0	9	5
434	B:B:R214	B:B:V213	3.92	No	No	0	9	4
435	B:B:E215	B:B:G216	4.91	No	No	0	3	4
436	B:B:E215	B:B:M217	6.77	No	No	0	3	3
437	B:B:F222	B:B:Q220	14.05	Yes	Yes	1	8	7
438	B:B:D258	B:B:Q220	13.05	Yes	Yes	1	7	7
439	B:B:Q220	G:G:I25	4.12	Yes	No	1	7	2
440	B:B:F222	B:B:F241	8.57	Yes	Yes	1	8	6
441	B:B:F222	B:B:F253	7.5	Yes	Yes	1	8	6
442	B:B:D258	B:B:F222	4.78	Yes	Yes	1	7	8
443	B:B:H225	B:B:T243	9.58	Yes	Yes	1	9	8
444	B:B:H225	B:B:S245	11.16	Yes	No	1	9	9
445	B:B:D247	B:B:H225	5.04	Yes	Yes	1	9	9
446	B:B:H225	B:B:R251	5.64	Yes	Yes	1	9	8
447	B:B:F253	B:B:H225	5.66	Yes	Yes	1	6	9
448	B:B:D247	B:B:E226	7.8	Yes	No	0	9	3
449	B:B:E226	B:B:R251	5.82	No	Yes	0	3	8
450	B:B:D228	B:B:S227	7.36	Yes	No	6	9	6
451	B:B:D246	B:B:S227	4.42	No	No	6	9	6
452	B:B:D228	B:B:D246	6.65	Yes	No	6	9	9
453	B:B:D246	B:B:N230	5.39	No	No	0	9	9
454	B:B:F241	B:B:I232	6.28	Yes	Yes	1	6	8
455	B:B:I232	B:B:T243	10.64	Yes	Yes	1	8	8
456	B:B:F234	B:B:F241	5.36	No	Yes	1	5	6
457	B:B:F235	B:B:P236	10.11	Yes	Yes	18	6	7
458	B:B:F235	B:B:F278	8.57	Yes	Yes	18	6	7
459	B:B:F235	G:G:L37	4.87	Yes	No	0	6	7
460	B:B:F235	G:G:C41	4.19	Yes	No	0	6	7
461	B:B:F278	B:B:P236	5.78	Yes	Yes	18	7	7
462	B:B:G282	B:B:P236	4.06	No	Yes	18	9	7
463	B:B:P236	G:G:Y40	5.56	Yes	No	0	7	6
464	B:B:N237	B:B:N239	6.81	No	No	0	5	2
465	B:B:N237	G:G:D36	4.04	No	No	0	5	5
466	B:B:N239	B:B:R256	7.23	No	No	0	2	9
467	B:B:F241	B:B:T243	3.89	Yes	Yes	1	6	8
468	B:B:F241	B:B:F253	11.79	Yes	Yes	1	6	6
469	B:B:A242	B:B:F278	4.16	No	Yes	0	4	7
470	B:B:F253	B:B:T243	3.89	Yes	Yes	1	6	8
471	B:B:G244	B:B:I273	3.53	No	No	0	5	6
472	B:B:D247	B:B:S245	8.83	Yes	No	1	9	9
473	B:B:D247	B:B:T249	10.12	Yes	No	1	9	6
474	B:B:R251	B:B:T249	7.76	Yes	No	1	8	6
475	B:B:T249	B:B:T263	4.71	No	Yes	1	6	1
476	B:B:C250	B:B:Y264	5.38	No	Yes	0	8	5
477	B:B:C250	B:B:I273	6.55	No	No	0	8	6
478	B:B:F253	B:B:R251	6.41	Yes	Yes	1	6	8
479	B:B:E260	B:B:R251	11.63	No	Yes	1	6	8
480	B:B:R251	B:B:T263	10.35	Yes	Yes	1	8	1
481	B:B:L252	B:B:L261	4.15	No	No	0	7	5
482	B:B:L252	B:B:Y264	3.52	No	Yes	0	7	5
483	B:B:E260	B:B:F253	4.66	No	Yes	1	6	6
484	B:B:D254	B:B:R256	3.57	Yes	No	0	9	9
485	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
486	B:B:D254	B:B:L261	4.07	Yes	No	0	9	5
487	B:B:D254	G:G:A33	4.63	Yes	No	0	9	7
488	B:B:R256	G:G:I28	6.26	No	No	0	9	4
489	B:B:D258	G:G:I25	5.6	Yes	No	1	7	2
490	B:B:D258	G:G:R27	7.15	Yes	Yes	1	7	8
491	B:B:Q259	G:G:V30	7.16	Yes	No	0	6	8
492	B:B:E260	B:B:T263	5.64	No	Yes	1	6	1
493	B:B:M262	B:B:Y264	4.79	No	Yes	0	4	5
494	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
495	B:B:W297	B:B:Y264	11.58	No	Yes	0	8	5
496	B:B:D267	B:B:H266	6.3	No	No	0	3	4
497	B:B:H266	B:B:N268	3.83	No	No	0	4	4
498	B:B:H266	B:B:R304	5.64	No	Yes	0	4	5
499	B:B:I269	B:B:Y289	8.46	No	Yes	0	4	7
500	B:B:C271	B:B:D290	4.67	No	Yes	2	5	6
501	B:B:C271	B:B:D291	4.67	No	No	0	5	8
502	B:B:D290	B:B:G272	5.03	Yes	No	0	6	4
503	B:B:I273	B:B:Y289	18.13	No	Yes	0	6	7
504	B:B:D290	B:B:T274	4.34	Yes	No	2	6	8
505	B:B:R314	B:B:T274	12.94	Yes	No	2	8	8
506	B:B:L285	B:B:V276	4.47	No	No	0	6	6
507	B:B:S277	B:B:V320	4.85	No	No	0	5	7
508	B:B:F278	B:B:G282	4.52	Yes	No	18	7	9
509	B:B:S279	B:B:S281	4.89	No	No	28	9	9
510	B:B:S279	G:G:D48	7.36	No	Yes	28	9	9
511	B:B:S281	G:G:D48	8.83	No	Yes	28	9	9
512	B:B:D298	B:B:R283	14.29	No	No	0	9	9
513	B:B:L300	B:B:R283	8.5	No	No	0	6	9
514	B:B:L284	B:B:V296	5.96	No	Yes	0	5	5
515	B:B:L286	B:B:L318	4.15	No	No	0	7	6
516	B:B:D291	B:B:Y289	10.34	No	Yes	0	8	7
517	B:B:N295	B:B:Y289	5.81	Yes	Yes	0	6	7
518	B:B:W297	B:B:Y289	7.72	No	Yes	0	8	7
519	B:B:D290	B:B:R314	5.96	Yes	Yes	2	6	8
520	B:B:D291	B:B:N293	14.81	No	Yes	0	8	5
521	B:B:F292	B:B:N313	3.62	No	No	0	4	7
522	B:B:N293	B:B:N295	5.45	Yes	Yes	19	5	6
523	B:B:N293	B:B:V307	4.43	Yes	No	19	5	3
524	B:B:C294	B:B:L308	4.76	No	No	0	5	7
525	B:B:N295	B:B:R304	20.49	Yes	Yes	19	6	5
526	B:B:N295	B:B:V307	4.43	Yes	No	19	6	3
527	B:B:G306	B:B:V296	3.68	No	Yes	0	4	5
528	B:B:R304	B:B:W297	8	Yes	No	0	5	8
529	B:B:D298	B:B:K301	9.68	No	Yes	0	9	5
530	B:B:R304	B:B:V307	3.92	Yes	No	19	5	3
531	B:B:L308	B:B:W339	20.5	No	Yes	25	7	9
532	B:B:H311	B:B:T329	8.21	Yes	No	0	9	8
533	B:B:H311	B:B:S331	16.74	Yes	No	0	9	9
534	B:B:H311	B:B:K337	11.79	Yes	Yes	0	9	6
535	B:B:D312	B:B:D333	6.65	No	No	0	5	9
536	B:B:D312	R:R:R214	7.15	No	No	0	5	7
537	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
538	B:B:D333	B:B:N313	6.73	No	No	0	9	7
539	B:B:R314	B:B:W332	22.99	Yes	Yes	2	8	9
540	B:B:S316	B:B:W332	4.94	No	Yes	2	9	9
541	B:B:V320	B:B:V327	4.81	No	No	0	7	6
542	B:B:D323	B:B:T321	7.23	Yes	No	16	7	7
543	B:B:D322	B:B:D323	3.99	No	Yes	16	1	7
544	B:B:D323	B:B:M325	13.86	Yes	No	0	7	5
545	B:B:M325	G:G:P49	5.03	No	No	0	5	7
546	B:B:T329	B:B:W339	8.49	No	Yes	0	8	9
547	B:B:F335	B:B:K337	4.96	No	Yes	0	4	6
548	B:B:K337	B:B:W339	5.8	Yes	Yes	0	6	9
549	B:B:N340	G:G:V54	4.43	No	Yes	3	9	6
550	B:B:N340	G:G:N59	13.62	No	No	3	9	9
551	G:G:Q11	G:G:S8	4.33	No	No	0	3	4
552	G:G:E17	G:G:K20	5.4	No	No	0	6	6
553	G:G:L19	G:G:Q18	5.32	Yes	No	0	9	9
554	G:G:I25	G:G:R27	7.52	No	Yes	1	2	8
555	G:G:H44	G:G:Y40	7.62	No	No	0	6	6
556	G:G:E47	G:G:H44	7.39	No	No	0	3	6
557	G:G:E47	G:G:K46	8.1	No	No	0	3	1
558	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
559	G:G:D48	G:G:L50	6.79	Yes	No	0	9	9
560	G:G:P49	G:G:V54	3.53	No	Yes	0	7	6
561	G:G:L51	G:G:T52	4.42	No	No	0	6	4
562	G:G:P55	G:G:V54	3.53	No	Yes	3	5	6
563	G:G:E58	G:G:V54	4.28	No	Yes	3	5	6
564	G:G:N59	G:G:V54	7.39	No	Yes	3	9	6
565	G:G:E58	G:G:P55	14.15	No	No	3	5	5
566	G:G:N59	G:G:P60	4.89	No	No	3	9	9
567	G:G:F61	G:G:P60	5.78	Yes	No	3	8	9
568	L:L:S1	R:R:Q364	4.33	No	No	0	0	7
569	L:L:V2	R:R:L292	4.47	Yes	Yes	8	0	6
570	L:L:V2	R:R:Y296	5.05	Yes	Yes	8	0	7
571	L:L:V2	R:R:Y421	10.09	Yes	Yes	8	0	8
572	L:L:S3	R:R:Y191	3.82	No	Yes	0	0	7
573	L:L:S3	R:R:E444	8.62	No	Yes	0	0	7
574	L:L:E4	R:R:Y195	4.49	No	Yes	0	0	7
575	L:L:E4	R:R:I237	12.3	No	No	0	0	7
576	L:L:E4	R:R:L292	7.95	No	Yes	0	0	6
577	R:R:K34	R:R:T33	7.51	No	No	0	4	7
578	R:R:E35	R:R:T33	15.52	No	No	0	5	7
579	R:R:E36	R:R:L40	5.3	No	No	0	6	5
580	R:R:R147	R:R:V126	5.23	Yes	No	0	3	4
581	R:R:A128	R:R:H143	4.39	No	No	0	5	3
582	R:R:P130	R:R:V129	3.53	No	No	0	5	5
583	R:R:C131	R:R:P132	5.65	No	No	0	9	9
584	R:R:C131	R:R:F138	11.17	No	Yes	0	9	4
585	R:R:C131	R:R:C170	7.28	No	No	0	9	9
586	R:R:I135	R:R:P132	5.08	Yes	No	0	7	9
587	R:R:D133	R:R:F138	5.97	No	Yes	0	2	4
588	R:R:D137	R:R:I135	8.4	No	Yes	0	5	7
589	R:R:F138	R:R:I135	10.05	Yes	Yes	0	4	7
590	R:R:D137	R:R:L174	5.43	No	No	0	5	3
591	R:R:F138	R:R:H140	19.23	Yes	No	0	4	3
592	R:R:K141	R:R:N139	5.6	No	No	0	3	4
593	R:R:E169	R:R:N139	5.26	No	No	0	5	4
594	R:R:E169	R:R:G142	6.55	No	No	0	5	5
595	R:R:A144	R:R:Y167	4	No	No	0	7	5
596	R:R:R147	R:R:Y145	6.17	Yes	No	0	3	4
597	R:R:N166	R:R:Y145	22.1	No	No	0	7	4
598	R:R:E155	R:R:R147	4.65	No	Yes	0	4	3
599	R:R:D149	R:R:E155	6.5	No	No	0	5	4
600	R:R:S153	R:R:W154	6.18	No	No	0	4	9
601	R:R:P158	R:R:V157	3.53	No	No	0	4	4
602	R:R:H160	R:R:V157	6.92	No	No	0	4	4
603	R:R:V157	R:R:W164	4.9	No	No	0	4	5
604	R:R:H160	R:R:R162	10.16	No	No	0	4	3
605	R:R:A165	R:R:Y167	5.34	No	No	0	7	5
606	R:R:N166	R:R:S168	8.94	No	No	0	7	6
607	R:R:Y191	R:R:Y195	17.87	Yes	Yes	8	7	7
608	R:R:M445	R:R:Y191	16.76	No	Yes	0	6	7
609	R:R:N448	R:R:Y191	6.98	Yes	Yes	8	6	7
610	R:R:F238	R:R:T192	5.19	No	No	0	7	7
611	R:R:G194	R:R:S449	3.71	No	No	0	9	9
612	R:R:R233	R:R:Y195	11.32	Yes	Yes	8	8	7
613	R:R:A234	R:R:Y195	4	No	Yes	0	8	7
614	R:R:N448	R:R:Y195	5.81	Yes	Yes	8	6	7
615	R:R:G452	R:R:S198	3.71	No	No	0	9	9
616	R:R:L199	R:R:M231	7.07	No	No	0	7	8
617	R:R:L199	R:R:V235	4.47	No	No	0	7	4
618	R:R:F453	R:R:S201	7.93	No	No	0	6	8
619	R:R:F227	R:R:L202	8.53	Yes	No	0	9	9
620	R:R:F230	R:R:L202	7.31	Yes	No	0	8	9
621	R:R:F461	R:R:V204	5.24	No	No	0	8	5
622	R:R:A205	R:R:F227	4.16	No	Yes	0	9	9
623	R:R:L209	R:R:N220	9.61	No	Yes	0	7	9
624	R:R:C460	R:R:L209	7.94	No	No	0	9	7
625	R:R:F212	R:R:Y211	12.38	Yes	No	0	7	2
626	R:R:F212	R:R:L215	3.65	Yes	No	0	7	9
627	R:R:F212	R:R:S473	5.28	Yes	No	0	7	4
628	R:R:E469	R:R:R214	9.3	No	No	0	9	7
629	R:R:L215	R:R:N220	4.12	No	Yes	0	9	9
630	R:R:E469	R:R:L215	5.3	No	No	0	9	9
631	R:R:C217	R:R:R219	6.96	No	Yes	0	8	9
632	R:R:T218	R:R:Y305	6.24	Yes	Yes	12	7	8
633	R:R:E317	R:R:T218	8.47	Yes	Yes	12	6	7
634	R:R:K318	R:R:T218	6.01	No	Yes	0	5	7
635	R:R:L321	R:R:T218	5.9	No	Yes	0	6	7
636	R:R:N220	R:R:R219	3.62	Yes	Yes	0	9	9
637	R:R:H223	R:R:N220	3.83	No	Yes	0	9	9
638	R:R:M224	R:R:Y221	3.59	No	No	5	5	7
639	R:R:H225	R:R:Y221	11.98	Yes	No	5	8	7
640	R:R:L321	R:R:Y221	7.03	No	No	0	6	7
641	R:R:E302	R:R:H223	8.62	No	No	0	9	9
642	R:R:H225	R:R:M224	7.88	Yes	No	5	8	5
643	R:R:H225	R:R:W298	13.75	Yes	Yes	5	8	9
644	R:R:H225	R:R:T325	5.48	Yes	No	0	8	5
645	R:R:H225	R:R:W329	7.41	Yes	Yes	5	8	9
646	R:R:F230	R:R:L226	4.87	Yes	No	0	8	9
647	R:R:L226	R:R:W298	7.97	No	Yes	0	9	9
648	R:R:E302	R:R:L226	7.95	No	No	0	9	9
649	R:R:F227	R:R:V455	5.24	Yes	No	0	9	9
650	R:R:C460	R:R:F227	8.38	No	Yes	0	9	9
651	R:R:N295	R:R:S229	10.43	No	No	0	8	9
652	R:R:S229	R:R:W298	4.94	No	Yes	5	9	9
653	R:R:S229	R:R:W329	6.18	No	Yes	5	9	9
654	R:R:F230	R:R:N295	13.29	Yes	No	0	8	8
655	R:R:F230	R:R:I299	5.02	Yes	No	0	8	9
656	R:R:F230	R:R:Q451	10.54	Yes	No	0	8	9
657	R:R:F230	R:R:G452	4.52	Yes	No	0	8	9
658	R:R:F230	R:R:V455	5.24	Yes	No	0	8	9
659	R:R:F291	R:R:L232	10.96	Yes	No	0	5	8
660	R:R:L292	R:R:R233	6.07	Yes	Yes	8	6	8
661	R:R:N295	R:R:R233	13.26	No	Yes	0	8	8
662	R:R:R233	R:R:Y296	5.14	Yes	Yes	8	8	7
663	R:R:N448	R:R:R233	3.62	Yes	Yes	8	6	8
664	R:R:F288	R:R:I237	5.02	No	No	0	7	7
665	R:R:A284	R:R:K240	6.42	No	No	0	6	7
666	R:R:R282	R:R:V285	6.54	No	No	0	8	6
667	R:R:R282	R:R:R343	9.6	No	No	0	8	8
668	R:R:T286	R:R:W339	3.64	No	Yes	0	7	8
669	R:R:T286	R:R:V340	6.35	No	No	0	7	5
670	R:R:F287	R:R:F291	7.5	No	Yes	0	3	5
671	R:R:I363	R:R:L289	11.42	No	No	0	7	7
672	R:R:F291	R:R:Y290	6.19	Yes	Yes	0	5	9
673	R:R:T294	R:R:Y290	7.49	No	Yes	5	8	9
674	R:R:P332	R:R:Y290	4.17	Yes	Yes	5	9	9
675	R:R:A333	R:R:Y290	4	No	Yes	0	5	9
676	R:R:V336	R:R:Y290	7.57	No	Yes	0	7	9
677	R:R:L292	R:R:Y296	4.69	Yes	Yes	8	6	7
678	R:R:A293	R:R:P332	3.74	No	Yes	0	6	9
679	R:R:T294	R:R:W329	3.64	No	Yes	5	8	9
680	R:R:P332	R:R:T294	6.99	Yes	No	5	9	8
681	R:R:I367	R:R:Y296	4.84	No	Yes	0	7	7
682	R:R:I371	R:R:Y296	4.84	No	Yes	8	7	7
683	R:R:Y296	R:R:Y421	15.89	Yes	Yes	8	7	8
684	R:R:L331	R:R:Y297	7.03	No	Yes	0	4	6
685	R:R:P332	R:R:Y297	5.56	Yes	Yes	5	9	6
686	R:R:F335	R:R:Y297	7.22	Yes	Yes	5	5	6
687	R:R:S370	R:R:Y297	5.09	No	Yes	0	7	6
688	R:R:V301	R:R:W298	9.81	No	Yes	0	8	9
689	R:R:W298	R:R:W329	10.31	Yes	Yes	5	9	9
690	R:R:F327	R:R:L300	3.65	No	No	0	5	8
691	R:R:L300	R:R:S370	4.5	No	No	0	8	7
692	R:R:L300	R:R:L373	6.92	No	No	0	8	7
693	R:R:F324	R:R:V301	5.24	No	No	0	7	8
694	R:R:E302	R:R:L416	14.58	No	No	0	9	9
695	R:R:F417	R:R:G303	6.02	Yes	No	0	9	9
696	R:R:L304	R:R:L377	4.15	No	No	0	5	7
697	R:R:S308	R:R:Y305	3.82	No	Yes	0	7	8
698	R:R:L309	R:R:Y305	9.38	Yes	Yes	12	8	8
699	R:R:E317	R:R:Y305	14.59	Yes	Yes	12	6	8
700	R:R:F324	R:R:Y305	6.19	No	Yes	0	7	8
701	R:R:I381	R:R:L306	5.71	No	No	0	9	9
702	R:R:F311	R:R:H307	10.18	No	Yes	0	6	8
703	R:R:H307	R:R:L377	11.57	Yes	No	0	8	7
704	R:R:H307	R:R:N380	6.38	Yes	No	0	8	8
705	R:R:H307	R:R:I381	5.3	Yes	No	0	8	9
706	R:R:F315	R:R:S308	11.89	Yes	No	0	6	7
707	R:R:F315	R:R:L309	4.87	Yes	Yes	0	6	8
708	R:R:E317	R:R:L309	11.93	Yes	Yes	12	6	8
709	R:R:I310	R:R:V384	4.61	No	No	0	8	8
710	R:R:F315	R:R:M312	8.71	Yes	No	0	6	5
711	R:R:K319	R:R:S316	6.12	No	No	0	6	7
712	R:R:V326	R:R:W322	6.13	No	No	0	4	3
713	R:R:F327	R:R:L331	4.87	No	No	0	5	4
714	R:R:L331	R:R:V334	4.47	No	No	0	4	4
715	R:R:F335	R:R:P332	5.78	Yes	Yes	5	5	9
716	R:R:F335	R:R:V334	5.24	Yes	No	0	5	4
717	R:R:F335	R:R:P366	15.89	Yes	No	0	5	9
718	R:R:R343	R:R:W339	9	No	Yes	0	8	8
719	R:R:I362	R:R:W339	10.57	No	Yes	0	8	8
720	R:R:I363	R:R:W339	11.74	No	Yes	0	7	8
721	R:R:L346	R:R:V342	7.45	No	No	0	3	5
722	R:R:I362	R:R:N358	9.91	No	No	0	8	4
723	R:R:Q364	R:R:W361	13.14	No	No	0	7	8
724	R:R:V365	R:R:W361	12.26	No	No	0	5	8
725	R:R:L368	R:R:Q364	9.32	No	No	0	4	7
726	R:R:P366	R:R:V365	7.07	No	No	0	9	5
727	R:R:I371	R:R:Y421	16.92	No	Yes	8	7	8
728	R:R:M425	R:R:V372	6.09	No	No	0	6	4
729	R:R:F417	R:R:N374	13.29	Yes	No	0	9	9
730	R:R:F375	R:R:I422	13.82	No	No	0	7	5
731	R:R:F417	R:R:L377	3.65	Yes	No	0	9	7
732	R:R:F378	R:R:L413	6.09	Yes	No	29	9	9
733	R:R:F378	R:R:F417	7.5	Yes	Yes	29	9	9
734	R:R:F378	R:R:V419	3.93	Yes	No	0	9	7
735	R:R:T410	R:R:V382	6.35	No	No	0	9	7
736	R:R:L385	R:R:S409	7.51	No	No	24	8	9
737	R:R:L389	R:R:Q402	7.99	No	No	0	8	6
738	R:R:Q402	R:R:T392	7.09	No	No	0	6	7
739	R:R:D398	R:R:Q401	10.44	No	No	0	6	6
740	R:R:Q402	R:R:T399	4.25	No	No	0	6	6
741	R:R:T399	R:R:Y403	3.75	No	No	0	6	7
742	R:R:R400	R:R:Y403	7.2	No	No	0	8	7
743	R:R:K405	R:R:R404	3.71	No	No	0	8	6
744	R:R:K408	R:R:R404	7.43	No	No	0	8	6
745	R:R:L407	R:R:L411	5.54	No	No	0	8	8
746	R:R:I458	R:R:V412	6.14	No	No	0	8	8
747	R:R:F417	R:R:L413	4.87	Yes	No	29	9	9
748	R:R:M414	R:R:V419	7.61	No	No	0	8	7
749	R:R:F454	R:R:P415	8.67	No	No	0	6	9
750	R:R:I458	R:R:P415	5.08	No	No	0	8	9
751	R:R:L416	R:R:Y459	19.93	No	No	0	9	8
752	R:R:F447	R:R:H420	11.31	No	No	0	5	8
753	R:R:H420	R:R:N448	5.1	No	Yes	0	8	6
754	R:R:H420	R:R:Q451	12.36	No	No	0	8	9
755	R:R:E444	R:R:Y421	7.86	Yes	Yes	0	7	8
756	R:R:I422	R:R:M425	4.37	No	No	0	5	6
757	R:R:F424	R:R:V423	11.8	No	No	0	7	6
758	R:R:E444	R:R:F424	7	Yes	No	0	7	7
759	R:R:V432	R:R:Y429	5.05	No	No	0	5	6
760	R:R:L446	R:R:Y443	4.69	No	No	0	5	4
761	R:R:F447	R:R:Y443	10.32	No	No	0	5	4
762	R:R:E444	R:R:N448	3.94	Yes	Yes	0	7	6
763	R:R:F450	R:R:S449	11.89	No	No	0	7	9
764	R:R:F450	R:R:F453	4.29	No	No	0	7	6
765	R:R:I458	R:R:Y459	12.09	No	No	0	8	8
766	R:R:E465	R:R:N463	3.94	No	Yes	0	9	9
767	R:R:N463	R:R:V466	5.91	Yes	No	0	9	9
768	R:R:E465	R:R:E469	6.34	No	No	0	9	9
769	A:A:F312	A:A:Q267	3.51	No	No	0	8	4
770	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
771	B:B:G319	B:B:M61	3.49	No	No	0	5	6
772	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
773	A:A:A48	A:A:S51	3.42	No	No	0	8	9
774	A:A:C365	A:A:V367	3.42	No	No	0	8	9
775	B:B:G77	B:B:L95	3.42	No	Yes	0	8	8
776	R:R:A456	R:R:S201	3.42	No	No	0	8	8
777	A:A:G206	B:B:N119	3.39	No	No	0	8	9
778	B:B:G144	B:B:N119	3.39	No	No	0	8	9
779	B:B:A257	G:G:V30	3.39	No	No	0	7	8
780	B:B:A305	B:B:V296	3.39	No	Yes	0	4	5
781	R:R:H216	R:R:R213	3.39	No	No	0	8	8
782	R:R:N358	R:R:W361	3.39	No	No	0	4	8
783	R:R:G464	R:R:N463	3.39	No	Yes	0	7	9
784	B:B:C148	B:B:T102	3.38	No	No	0	6	8
785	B:B:C149	B:B:T102	3.38	No	No	0	8	8
786	B:B:C121	B:B:T159	3.38	No	Yes	7	8	9
787	B:B:C149	B:B:T159	3.38	No	Yes	7	8	9
788	A:A:G226	A:A:Q227	3.29	No	No	0	9	9
789	R:R:G418	R:R:Q451	3.29	No	No	0	9	9
790	A:A:I26	B:B:A92	3.25	No	No	0	9	6
791	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
792	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
793	B:B:A28	B:B:I33	3.25	No	No	0	4	3
794	B:B:A140	B:B:I120	3.25	No	No	0	5	6
795	A:A:D323	A:A:P321	3.22	No	Yes	0	4	5
796	A:A:V301	A:A:V334	3.21	No	No	0	7	4
797	R:R:A468	R:R:K472	3.21	No	No	0	5	7
798	A:A:R356	A:A:R389	3.2	No	No	0	2	4
799	B:B:S265	B:B:T263	3.2	No	Yes	0	2	1
800	B:B:G310	B:B:H311	3.18	No	Yes	0	5	9
801	B:B:T274	B:B:V315	3.17	No	No	0	8	7
802	B:B:C294	B:B:L318	3.17	No	No	0	5	6
803	B:B:L14	G:G:A23	3.15	No	No	0	8	8
804	B:B:A242	B:B:L285	3.15	No	No	0	4	6
805	R:R:A456	R:R:L202	3.15	No	No	0	8	9
806	R:R:A386	R:R:L406	3.15	No	No	0	6	8
807	A:A:E314	A:A:P313	3.14	No	No	0	6	6
808	A:A:E327	A:A:P328	3.14	No	No	0	4	1
809	A:A:I341	A:A:S250	3.1	No	Yes	0	8	6
810	B:B:I338	B:B:S84	3.1	No	No	0	5	5
811	B:B:I123	B:B:S136	3.1	Yes	No	0	6	4
812	B:B:A193	B:B:D195	3.09	No	No	0	4	5
813	R:R:F315	R:R:Y320	3.09	Yes	No	0	6	4
814	L:L:I5	L:L:V2	3.07	No	Yes	0	0	0
815	G:G:K29	G:G:S31	3.06	No	No	0	4	9
816	R:R:H143	R:R:P130	3.05	No	No	0	3	5
817	A:A:M221	A:A:V57	3.04	No	No	0	8	7
818	B:B:M45	B:B:V327	3.04	No	No	0	4	6
819	B:B:I229	B:B:T243	3.04	No	Yes	0	7	8
820	R:R:M224	R:R:V206	3.04	No	No	0	5	5
821	A:A:F208	A:A:G225	3.01	No	No	0	5	9
822	A:A:L346	A:A:S349	3	No	No	0	4	7
823	B:B:L4	G:G:S8	3	No	No	0	4	4
824	B:B:K301	B:B:T34	3	Yes	No	0	5	5
825	B:B:G174	B:B:R137	3	No	No	0	4	5
826	B:B:L318	B:B:S275	3	No	No	0	6	8
827	B:B:L284	B:B:S279	3	No	No	0	5	9
828	B:B:L7	G:G:V16	2.98	No	No	0	8	7
829	B:B:L286	B:B:V296	2.98	No	Yes	0	7	5
830	B:B:V327	G:G:L50	2.98	No	No	0	6	9
831	R:R:L174	R:R:V171	2.98	No	No	0	3	3
832	B:B:L30	B:B:T34	2.95	Yes	No	0	5	5
833	B:B:L152	B:B:T196	2.95	Yes	No	0	3	1
834	R:R:L406	R:R:T410	2.95	No	No	0	8	9
835	B:B:I123	B:B:I171	2.94	Yes	Yes	0	6	6
836	B:B:I157	B:B:I171	2.94	No	Yes	0	7	6
837	R:R:D149	R:R:S153	2.94	No	No	0	5	4
838	R:R:I371	R:R:I422	2.94	No	No	0	7	5
839	G:G:A43	G:G:H44	2.93	No	No	0	4	6
840	R:R:G323	R:R:Y320	2.9	No	No	0	1	4
841	B:B:D322	B:B:T65	2.89	No	No	0	1	1
842	G:G:E58	G:G:S57	2.87	No	No	0	5	6
843	A:A:I244	A:A:L44	2.85	No	No	2	8	9
844	A:A:I244	A:A:L46	2.85	No	No	2	8	8
845	A:A:I235	A:A:L282	2.85	No	Yes	0	9	9
846	A:A:I276	A:A:L282	2.85	No	Yes	0	8	9
847	A:A:I285	A:A:L282	2.85	No	Yes	0	7	9
848	R:R:I190	R:R:L446	2.85	No	No	0	6	5
849	R:R:I222	R:R:L321	2.85	No	No	0	9	6
850	R:R:L228	R:R:M231	2.83	No	No	0	4	8
851	R:R:E391	R:R:T387	2.82	No	No	0	7	7
852	R:R:K405	R:R:L389	2.82	No	No	0	8	8
853	R:R:G328	R:R:W298	2.81	No	Yes	0	9	9
854	R:R:G323	R:R:W322	2.81	No	No	0	1	3
855	B:B:H54	B:B:S334	2.79	Yes	No	0	9	4
856	A:A:D33	A:A:K32	2.77	No	No	0	5	4
857	A:A:A269	A:A:F345	2.77	No	Yes	0	9	8
858	A:A:A337	A:A:F315	2.77	No	Yes	0	8	6
859	A:A:L388	A:A:L393	2.77	No	No	0	8	8
860	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
861	B:B:L210	B:B:L255	2.77	No	No	0	5	6
862	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
863	B:B:L284	G:G:L51	2.77	No	No	0	5	6
864	B:B:D303	B:B:K301	2.77	No	Yes	0	2	5
865	B:B:A326	G:G:F61	2.77	No	Yes	0	7	8
866	G:G:A56	G:G:R62	2.77	No	No	0	4	7
867	R:R:I135	R:R:Q37	2.74	Yes	No	0	7	7
868	A:A:M386	A:A:Q390	2.72	No	No	0	3	4
869	A:A:K32	A:A:Q29	2.71	No	No	0	4	4
870	A:A:K32	A:A:Q35	2.71	No	No	0	4	3
871	G:G:E17	G:G:M21	2.71	No	No	0	6	1
872	A:A:E309	A:A:K307	2.7	No	No	0	4	6
873	R:R:C170	R:R:Y167	2.69	No	No	0	9	5
874	B:B:A299	B:B:Y264	2.67	No	Yes	0	5	5
875	B:B:A287	B:B:Y289	2.67	No	Yes	0	6	7
876	R:R:A44	R:R:Y134	2.67	No	Yes	0	7	5
877	G:G:L15	G:G:Q11	2.66	No	No	0	2	3
878	R:R:F288	R:R:S236	2.64	No	No	0	7	7
879	R:R:F291	R:R:S236	2.64	Yes	No	0	5	7
880	A:A:E15	A:A:N14	2.63	No	No	0	6	3
881	B:B:R96	B:B:V135	2.62	No	Yes	0	6	4
882	R:R:R383	R:R:V384	2.62	No	No	0	8	8
883	A:A:D229	A:A:E230	2.6	No	No	0	8	9
884	B:B:R49	B:B:T87	2.59	No	No	0	7	5
885	R:R:F378	R:R:T410	2.59	Yes	No	0	9	9
886	A:A:E16	A:A:Q19	2.55	No	Yes	0	4	4
887	A:A:V301	A:A:Y253	2.52	No	Yes	0	7	8
888	B:B:I171	B:B:R137	2.51	Yes	No	0	6	5
889	R:R:F461	R:R:I208	2.51	No	No	0	8	8
890	R:R:F212	R:R:I470	2.51	Yes	No	0	7	5
891	R:R:F454	R:R:I457	2.51	No	No	0	6	6
892	R:R:F461	R:R:I457	2.51	No	No	0	8	6
893	R:R:F288	R:R:K240	2.48	No	No	0	7	7
894	B:B:S98	B:B:W99	2.47	No	Yes	0	8	9
895	R:R:L187	R:R:R186	2.43	No	No	0	5	5
896	R:R:D398	R:R:R400	2.38	No	No	0	6	8
897	A:A:L266	A:A:Y253	2.34	No	Yes	0	8	8
898	A:A:E314	A:A:R317	2.33	No	No	0	6	2
899	R:R:L228	R:R:W329	2.28	No	Yes	0	4	9
900	B:B:R19	B:B:R22	2.13	No	Yes	0	4	6
901	B:B:G115	B:B:G116	2.11	No	No	0	9	9
902	B:B:W339	R:R:R476	2	Yes	No	0	9	7
903	R:R:R147	R:R:W164	2	Yes	No	0	3	5
904	B:B:C294	B:B:G288	1.96	No	No	0	5	7
905	R:R:C148	R:R:G152	1.96	No	No	0	9	9
906	R:R:A279	R:R:G280	1.95	No	No	0	4	4
907	B:B:A106	B:B:P107	1.87	No	No	0	6	6
908	B:B:A193	B:B:P194	1.87	No	No	0	4	4
909	B:B:G41	B:B:V40	1.84	No	No	0	1	3
910	B:B:G324	B:B:V320	1.84	No	No	0	9	7
911	R:R:G194	R:R:V193	1.84	No	No	0	9	6
912	R:R:G194	R:R:V197	1.84	No	No	0	9	5
913	B:B:G185	B:B:T164	1.82	No	No	0	5	6
914	B:B:G185	B:B:T184	1.82	No	No	0	5	3
915	B:B:A60	B:B:C103	1.81	No	No	0	7	8
916	A:A:P326	A:A:T325	1.75	No	No	0	1	2
917	G:G:P53	G:G:T52	1.75	No	No	0	8	4
918	R:R:P428	R:R:T427	1.75	No	No	0	7	5
919	A:A:G52	A:A:K293	1.74	No	Yes	0	9	9
920	B:B:C233	B:B:S191	1.72	No	No	0	3	8
921	B:B:C233	B:B:S277	1.72	No	No	0	3	5
922	A:A:A351	A:A:S352	1.71	No	No	0	4	5
923	B:B:S281	G:G:A45	1.71	No	No	0	9	4
924	R:R:C148	R:R:V127	1.71	No	No	0	9	7
925	R:R:G188	R:R:L187	1.71	No	No	0	5	5
926	R:R:C281	R:R:V285	1.71	No	No	0	9	6
927	A:A:A298	A:A:V334	1.7	No	No	0	4	4
928	B:B:E130	B:B:G131	1.64	Yes	No	0	3	4
929	R:R:S341	R:R:V342	1.62	No	No	0	5	5
930	A:A:A22	A:A:K25	1.61	No	No	0	4	5
931	A:A:A372	A:A:M60	1.61	No	No	0	8	9
932	B:B:A302	B:B:M262	1.61	No	No	0	2	4
933	G:G:A39	G:G:M38	1.61	No	No	0	3	4
934	A:A:S349	A:A:T350	1.6	No	No	0	7	4
935	R:R:V127	R:R:V129	1.6	No	No	0	7	5
936	R:R:V235	R:R:V239	1.6	No	No	0	4	5
937	R:R:G142	R:R:H143	1.59	No	No	0	5	3
938	R:R:G159	R:R:H160	1.59	No	No	0	3	4
939	B:B:L4	G:G:A12	1.58	No	No	0	4	5
940	B:B:L7	G:G:A12	1.58	No	No	0	8	5
941	B:B:A11	G:G:L19	1.58	No	Yes	0	5	9
942	B:B:T165	B:B:T181	1.57	No	No	0	7	2
943	B:B:T179	B:B:T181	1.57	No	No	0	4	2
944	B:B:A309	B:B:N293	1.56	No	Yes	0	3	5
945	G:G:A23	G:G:N24	1.56	No	No	0	8	1
946	B:B:A21	B:B:D20	1.54	No	No	0	4	2
947	B:B:A240	B:B:D254	1.54	No	Yes	0	6	9
948	R:R:I362	R:R:V342	1.54	No	No	0	8	5
949	R:R:I379	R:R:V382	1.54	No	No	0	5	7
950	B:B:A28	B:B:Q32	1.52	No	No	0	4	1
951	A:A:A298	A:A:E299	1.51	No	No	0	4	6
952	G:G:A43	G:G:E42	1.51	No	No	0	4	1
953	R:R:M231	R:R:T203	1.51	No	No	0	8	3
954	A:A:G355	A:A:R389	1.5	No	No	0	2	4
955	B:B:T181	G:G:K14	1.5	No	No	0	2	4
956	R:R:K388	R:R:T387	1.5	No	No	0	9	7
957	A:A:L302	A:A:V334	1.49	No	No	0	2	4
958	A:A:D223	A:A:S54	1.47	Yes	No	0	9	9
959	B:B:I37	G:G:M38	1.46	Yes	No	0	2	4
960	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
961	B:B:I18	B:B:K15	1.45	Yes	No	0	7	6
962	G:G:I28	G:G:K32	1.45	No	No	0	4	5
963	L:L:I5	R:R:K360	1.45	No	No	0	0	7
964	R:R:G330	R:R:Y290	1.45	No	Yes	0	7	9
965	R:R:I470	R:R:K471	1.45	No	No	0	5	5
966	G:G:K29	G:G:K32	1.44	No	No	0	4	5
967	R:R:K359	R:R:K360	1.44	No	No	0	3	7
968	R:R:K471	R:R:K472	1.44	No	No	0	5	7
969	B:B:L4	G:G:I9	1.43	No	No	0	4	2
970	R:R:I135	R:R:L41	1.43	Yes	No	0	7	8
971	B:B:L14	G:G:K20	1.41	No	No	0	8	6
972	B:B:G141	B:B:W169	1.41	No	Yes	0	5	8
973	B:B:E172	B:B:T173	1.41	No	No	0	6	5
974	B:B:G182	B:B:W211	1.41	No	Yes	0	6	8
975	R:R:E36	R:R:T33	1.41	No	No	0	6	7
976	R:R:L187	R:R:M445	1.41	No	No	0	5	6
977	R:R:E431	R:R:T430	1.41	No	No	0	3	5
978	R:R:K172	R:R:N139	1.4	No	No	0	3	4
979	A:A:L394	R:R:L389	1.38	No	No	0	8	8
980	G:G:L15	G:G:L19	1.38	No	Yes	0	2	9
981	A:A:I62	A:A:Q213	1.37	No	No	0	9	3
982	A:A:K28	A:A:Q29	1.36	No	No	0	4	4
983	A:A:M60	A:A:Q59	1.36	No	No	0	9	9
984	B:B:K23	B:B:Q259	1.36	No	Yes	0	2	6
985	R:R:D149	R:R:N151	1.35	No	No	0	5	5
986	B:B:N16	B:B:Q17	1.32	No	No	0	1	4
987	R:R:F238	R:R:S196	1.32	No	No	0	7	7
988	R:R:R146	R:R:V127	1.31	No	No	0	8	7
989	R:R:F424	R:R:T427	1.3	No	No	0	7	5
990	A:A:R283	A:A:T284	1.29	No	No	0	3	4
991	B:B:Q13	B:B:Q17	1.28	No	No	0	1	4
992	A:A:E27	A:A:Q31	1.27	No	No	0	6	4
993	B:B:E10	B:B:Q6	1.27	No	No	0	8	1
994	A:A:I62	A:A:R61	1.25	No	No	0	9	8
995	R:R:M189	R:R:R186	1.24	No	No	0	4	5
996	R:R:E444	R:R:H442	1.23	Yes	No	0	7	5
997	R:R:F39	R:R:L40	1.22	No	No	0	7	5
998	R:R:T163	R:R:W154	1.21	No	No	0	5	9
999	R:R:D241	R:R:F238	1.19	No	No	0	8	7
1000	B:B:Q44	B:B:R42	1.17	No	No	0	4	2
1001	R:R:L40	R:R:Y134	1.17	No	Yes	0	5	5
1002	G:G:E17	G:G:R13	1.16	No	No	0	6	6
1003	R:R:D133	R:R:Y134	1.15	No	Yes	0	2	5
1004	R:R:Q47	R:R:Y134	1.13	No	Yes	0	6	5
1005	A:A:R280	A:A:R283	1.07	Yes	No	0	5	3
1006	A:A:R283	A:A:R356	1.07	No	No	0	3	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Q19	6.675	4	3	4
2	A:A:N218	5.76	4	14	4
3	A:A:F219	6.83833	6	0	8
4	A:A:H220	9.2025	4	14	7
5	A:A:D223	4.6475	4	20	9
6	A:A:K233	8.355	4	6	9
7	A:A:W234	7.302	5	0	9
8	A:A:F238	9.848	5	2	9
9	A:A:S250	5.93	4	10	6
10	A:A:Y253	7.06857	7	10	8
11	A:A:F273	5.86571	7	9	9
12	A:A:W277	10.224	5	9	6
13	A:A:R280	8.2875	4	2	5
14	A:A:W281	10.54	5	2	5
15	A:A:L282	5.2275	4	0	9
16	A:A:I288	4.838	5	22	9
17	A:A:L289	5.1475	4	9	9
18	A:A:N292	6.0975	4	0	9
19	A:A:K293	5.3225	4	0	9
20	A:A:Q294	7.5475	4	10	6
21	A:A:F315	8.188	5	0	6
22	A:A:P321	5.595	4	0	5
23	A:A:Y339	6.032	5	0	3
24	A:A:F345	6.784	5	9	8
25	A:A:Y360	8.15	4	22	8
26	A:A:T364	6.3975	4	23	9
27	A:A:R373	6.9025	4	15	5
28	A:A:F376	5.3825	4	15	8
29	A:A:R380	5.135	4	0	7
30	B:B:I18	4.4225	4	0	7
31	B:B:R22	6.288	5	1	6
32	B:B:L30	5.465	4	0	5
33	B:B:I37	4.9	4	0	2
34	B:B:H54	7.71333	6	11	9
35	B:B:K57	8.196	5	2	9
36	B:B:Y59	9.724	5	2	8
37	B:B:W63	7.634	5	0	7
38	B:B:R68	7.37	5	3	5
39	B:B:L69	4.7975	4	3	5
40	B:B:V71	4.812	5	0	8
41	B:B:D76	7.1675	4	0	9
42	B:B:W82	8.73167	6	11	9
43	B:B:D83	5.4525	4	3	8
44	B:B:T86	5.9825	4	3	6
45	B:B:N88	9.79	4	3	7
46	B:B:K89	5.498	5	11	9
47	B:B:L95	4.766	5	13	8
48	B:B:W99	7.906	5	2	9
49	B:B:M101	4.3275	4	0	9
50	B:B:Y105	4.968	5	0	6
51	B:B:N110	8.46	4	17	4
52	B:B:Y111	9.025	4	17	4
53	B:B:I123	4.59	4	0	6
54	B:B:Y124	6.716	5	13	6
55	B:B:E130	7.958	5	26	3
56	B:B:V135	5.2725	4	13	4
57	B:B:H142	8.756	5	7	9
58	B:B:Y145	6.798	5	6	8
59	B:B:F151	6.1625	4	0	9
60	B:B:L152	4.2225	4	0	3
61	B:B:T159	4.9175	4	7	9
62	B:B:D163	9.2025	4	7	9
63	B:B:W169	6.98571	7	7	8
64	B:B:I171	3.16	4	0	6
65	B:B:F180	8.94	4	4	7
66	B:B:H183	7.28667	6	4	9
67	B:B:M188	6.3175	4	6	8
68	B:B:R197	7.7275	4	27	5
69	B:B:F199	7.6025	4	4	9
70	B:B:C204	6.224	5	6	7
71	B:B:D205	7.4225	4	4	9
72	B:B:K209	8.885	4	4	6
73	B:B:W211	6.96571	7	4	8
74	B:B:D212	9.6825	4	27	9
75	B:B:Q220	9.4675	4	1	7
76	B:B:F222	8.725	4	1	8
77	B:B:H225	6.42333	6	1	9
78	B:B:D228	7.762	5	6	9
79	B:B:I232	6.162	5	1	8
80	B:B:F235	6.935	4	18	6
81	B:B:P236	6.3775	4	18	7
82	B:B:F241	6.64714	7	1	6
83	B:B:T243	6.208	5	1	8
84	B:B:D247	7.9475	4	1	9
85	B:B:R251	7.935	6	1	8
86	B:B:F253	6.65167	6	1	6
87	B:B:D254	3.688	5	0	9
88	B:B:D258	8.26	5	1	7
89	B:B:Q259	4.435	4	0	6
90	B:B:T263	5.975	4	1	1
91	B:B:Y264	5.43833	6	0	5
92	B:B:F278	5.7575	4	18	7
93	B:B:Y289	8.855	6	0	7
94	B:B:D290	6.24833	6	2	6
95	B:B:N293	6.5625	4	19	5
96	B:B:N295	9.045	4	19	6
97	B:B:V296	4.124	5	0	5
98	B:B:K301	5.838	5	0	5
99	B:B:R304	9.5125	4	19	5
100	B:B:H311	9.98	4	0	9
101	B:B:R314	12.4725	4	2	8
102	B:B:D323	8.8475	4	16	7
103	B:B:W332	10.3129	7	2	9
104	B:B:K337	9.7675	4	0	6
105	B:B:W339	8.522	5	25	9
106	G:G:L19	3.455	4	0	9
107	G:G:R27	6.156	5	1	8
108	G:G:D48	6.116	5	28	9
109	G:G:V54	4.632	5	3	6
110	G:G:F61	6.862	5	3	8
111	L:L:V2	5.67	4	8	0
112	R:R:Y134	1.53	4	0	5
113	R:R:I135	5.54	5	0	7
114	R:R:F138	11.605	4	0	4
115	R:R:R147	4.5125	4	0	3
116	R:R:Y191	11.3575	4	8	7
117	R:R:Y195	8.698	5	8	7
118	R:R:F212	5.955	4	0	7
119	R:R:T218	6.655	4	12	7
120	R:R:R219	6.5575	4	0	9
121	R:R:N220	5.295	4	0	9
122	R:R:H225	9.3	5	5	8
123	R:R:F227	6.5775	4	0	9
124	R:R:F230	7.25571	7	0	8
125	R:R:R233	7.882	5	8	8
126	R:R:Y290	5.145	6	5	9
127	R:R:F291	6.8225	4	0	5
128	R:R:L292	5.795	4	8	6
129	R:R:Y296	6.74167	6	8	7
130	R:R:Y297	6.225	4	5	6
131	R:R:W298	8.265	6	5	9
132	R:R:Y305	8.044	5	12	8
133	R:R:H307	8.3575	4	0	8
134	R:R:L309	12.01	4	12	8
135	R:R:F315	7.14	4	0	6
136	R:R:E317	10.285	4	12	6
137	R:R:W329	5.964	5	5	9
138	R:R:P332	5.248	5	5	9
139	R:R:F335	8.5325	4	5	5
140	R:R:W339	8.7375	4	0	8
141	R:R:F378	5.0275	4	29	9
142	R:R:F417	7.066	5	29	9
143	R:R:Y421	12.69	4	8	8
144	R:R:E444	5.73	5	0	7
145	R:R:N448	5.09	5	8	6
146	R:R:N463	4.295	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:D76	B:B:S74	90.5969	10.31	Yes	No	0	9	9
2	B:B:H54	B:B:S74	90.0195	11.16	Yes	No	0	9	9
3	B:B:H54	B:B:W82	80.4929	9.52	Yes	Yes	11	9	9
4	B:B:L70	B:B:W82	75.469	5.69	No	Yes	11	5	9
5	B:B:L70	B:B:W63	75.2652	11.39	No	Yes	0	5	7
6	B:B:S84	B:B:W63	43.8282	4.94	No	Yes	0	5	7
7	B:B:S84	G:G:F61	42.5893	7.93	No	Yes	0	5	8
8	B:B:Y85	G:G:F61	35.1717	9.28	No	Yes	3	4	8
9	B:B:R68	B:B:Y85	39.2344	18.52	Yes	No	3	5	4
10	A:A:Q390	R:R:R219	10.637	10.51	No	Yes	0	4	9
11	R:R:N220	R:R:R219	20.9695	3.62	Yes	Yes	0	9	9
12	R:R:L215	R:R:N220	90.7303	4.12	No	Yes	0	9	9
13	R:R:E469	R:R:L215	93.6106	5.3	No	No	0	9	9
14	R:R:E469	R:R:R214	95.745	9.3	No	No	0	9	7
15	B:B:D312	R:R:R214	96.0985	7.15	No	No	0	5	7
16	B:B:D312	B:B:D333	96.4515	6.65	No	No	0	5	9
17	B:B:D333	B:B:N313	96.8038	6.73	No	No	0	9	7
18	B:B:N313	B:B:W332	97.5066	5.65	No	Yes	0	7	9
19	B:B:K57	B:B:W332	59.4147	11.6	Yes	Yes	2	9	9
20	A:A:D240	B:B:K57	58.6572	5.53	No	Yes	0	6	9
21	A:A:D240	A:A:R42	55.6985	4.76	No	No	0	6	9
22	A:A:R42	A:A:Y37	100	13.38	No	No	0	9	4
23	A:A:Y37	B:B:L55	49.8785	4.69	No	No	0	4	6
24	B:B:D76	B:B:L55	49.5777	5.43	Yes	No	0	9	6
25	A:A:Y37	B:B:A56	49.8785	4	No	No	0	4	7
26	B:B:A56	B:B:D76	49.5777	4.63	No	Yes	0	7	9
27	A:A:D381	A:A:Y360	17.0866	12.64	No	Yes	0	8	8
28	A:A:D381	A:A:R385	21.1573	11.91	No	No	0	8	5
29	A:A:R385	A:A:Y358	26.1596	11.32	No	No	0	5	4
30	A:A:G355	A:A:Y358	26.4091	5.79	No	No	0	2	4
31	A:A:G355	A:A:R389	26.6663	1.5	No	No	0	2	4
32	A:A:R356	A:A:R389	26.925	3.2	No	No	0	2	4
33	A:A:R283	A:A:R356	27.1841	1.07	No	No	0	3	2
34	A:A:R280	A:A:R283	27.7529	1.07	Yes	No	0	5	3
35	A:A:R280	A:A:W281	52.4121	15.99	Yes	Yes	2	5	5
36	A:A:W281	B:B:W332	84.5006	12.18	Yes	Yes	2	5	9
37	A:A:R42	A:A:V241	45.0612	3.92	No	No	0	9	9
38	A:A:F238	A:A:V241	44.857	3.93	Yes	No	0	9	9
39	A:A:Y253	A:A:Y311	12.9414	5.96	Yes	No	0	8	6
40	A:A:L297	A:A:Y253	56.5377	3.52	No	Yes	10	8	8
41	A:A:L297	A:A:S250	28.7821	6.01	No	Yes	10	8	6
42	A:A:L291	A:A:S250	30.3538	4.5	No	Yes	10	8	6
43	A:A:L291	A:A:V248	77.3553	4.47	No	No	0	8	7
44	A:A:F345	A:A:V248	78.0927	5.24	Yes	No	0	8	7
45	A:A:F273	A:A:F345	41.3008	6.43	Yes	Yes	9	9	8
46	A:A:F246	A:A:F273	46.3031	4.29	No	Yes	9	9	9
47	A:A:F246	A:A:L272	87.7153	7.31	No	No	0	9	8
48	A:A:L272	A:A:R231	88.0022	6.07	No	No	0	8	9
49	A:A:R231	A:A:W234	88.3017	9	No	Yes	0	9	9
50	A:A:F238	A:A:W234	46.9472	4.01	Yes	Yes	0	9	9
51	A:A:L297	A:A:Q294	29.3731	6.65	No	Yes	10	8	6
52	A:A:L291	A:A:Q294	46.2642	6.65	No	Yes	10	8	6
53	A:A:F345	A:A:L289	40.4739	4.87	Yes	Yes	9	8	9
54	A:A:F246	A:A:L289	41.1408	3.65	No	Yes	9	9	9
55	A:A:K338	A:A:Y339	16.6929	5.97	No	Yes	0	5	3
56	A:A:K338	A:A:Q294	17.4154	6.78	No	Yes	0	5	6
57	A:A:E230	A:A:R232	12.6151	9.3	No	No	0	9	8
58	A:A:R232	B:B:C204	13.3657	4.18	No	Yes	6	8	7
59	A:A:W234	B:B:Y145	72.9437	7.72	Yes	Yes	0	9	8
60	B:B:M188	B:B:Y145	11.6912	4.79	Yes	Yes	6	8	8
61	A:A:E230	A:A:R228	11.06	15.12	No	No	0	9	9
62	A:A:R228	B:B:T164	10.2927	3.88	No	No	0	9	6
63	A:A:I308	A:A:Y253	21.1134	9.67	No	Yes	0	7	8
64	A:A:F315	A:A:I308	19.5093	8.79	Yes	No	0	6	7
65	A:A:R280	B:B:C271	37.8934	4.18	Yes	No	2	5	5
66	A:A:W281	B:B:D290	31.785	5.58	Yes	Yes	2	5	6
67	B:B:C271	B:B:D290	62.5921	4.67	No	Yes	2	5	6
68	B:B:R314	B:B:W332	32.6011	22.99	Yes	Yes	2	8	9
69	B:B:D290	B:B:R314	31.7609	5.96	Yes	Yes	2	6	8
70	A:A:V301	A:A:Y253	14.8009	2.52	No	Yes	0	7	8
71	A:A:E309	A:A:F315	10.1395	5.83	No	Yes	0	4	6
72	G:G:D48	G:G:P49	28.5505	4.83	Yes	No	0	9	7
73	G:G:D48	G:G:L50	21.2598	6.79	Yes	No	0	9	9
74	B:B:V327	G:G:L50	20.8861	2.98	No	No	0	6	9
75	B:B:V320	B:B:V327	14.41	4.81	No	No	0	7	6
76	B:B:S277	B:B:V320	14.0772	4.85	No	No	0	5	7
77	B:B:C233	B:B:S277	13.9289	1.72	No	No	0	3	5
78	B:B:C233	B:B:S191	14.3779	1.72	No	No	0	3	8
79	B:B:F222	B:B:F241	17.6606	8.57	Yes	Yes	1	8	6
80	B:B:D258	B:B:F222	21.0087	4.78	Yes	Yes	1	7	8
81	B:B:D258	B:B:R22	24.3109	10.72	Yes	Yes	1	7	6
82	B:B:I18	B:B:R22	16.5891	7.52	Yes	Yes	0	7	6
83	B:B:I18	G:G:A23	14.6188	3.25	Yes	No	0	7	8
84	B:B:L14	G:G:A23	13.3021	3.15	No	No	0	8	8
85	B:B:Q259	B:B:R22	38.9682	4.67	Yes	Yes	0	6	6
86	B:B:Q259	G:G:V30	40.1373	7.16	Yes	No	0	6	8
87	B:B:A257	G:G:V30	40.5937	3.39	No	No	0	7	8
88	B:B:A257	B:B:D254	41.109	4.63	No	Yes	0	7	9
89	B:B:C271	B:B:D291	99.6965	4.67	No	No	0	5	8
90	B:B:D291	B:B:Y289	89.2938	10.34	No	Yes	0	8	7
91	B:B:W297	B:B:Y289	80.8041	7.72	No	Yes	0	8	7
92	B:B:W297	B:B:Y264	77.5681	11.58	No	Yes	0	8	5
93	B:B:M262	B:B:Y264	20.5795	4.79	No	Yes	0	4	5
94	B:B:L30	B:B:M262	18.8781	9.9	Yes	No	0	5	4
95	B:B:L30	B:B:T34	12.9038	2.95	Yes	No	0	5	5
96	B:B:K301	B:B:T34	12.0478	3	Yes	No	0	5	5
97	B:B:M45	B:B:V327	12.8133	3.04	No	No	0	4	6
98	B:B:M101	B:B:Y59	70.2724	5.99	Yes	Yes	0	9	8
99	B:B:G162	B:B:Y145	35.7312	8.69	No	Yes	0	9	8
100	B:B:G162	B:B:S161	35.3477	3.71	No	No	0	9	9
101	B:B:H142	B:B:S161	32.6301	9.76	Yes	No	7	9	9
102	B:B:H142	B:B:T159	12.9084	6.85	Yes	Yes	7	9	9
103	B:B:C149	B:B:T159	14.9495	3.38	No	Yes	7	8	9
104	B:B:C149	B:B:T102	14.6697	3.38	No	No	0	8	8
105	B:B:C148	B:B:T102	14.3674	3.38	No	No	0	6	8
106	B:B:T321	B:B:W63	29.3456	12.13	No	Yes	0	7	7
107	B:B:L69	B:B:R68	27.7618	3.64	Yes	Yes	3	5	5
108	B:B:L69	B:B:Y105	27.2141	4.69	Yes	Yes	0	5	6
109	B:B:D323	B:B:T321	26.8321	7.23	Yes	No	16	7	7
110	B:B:V71	B:B:Y105	24.3127	5.05	Yes	Yes	0	8	6
111	B:B:L79	B:B:V71	19.1962	4.47	No	Yes	0	7	8
112	B:B:V135	B:B:Y124	10.364	6.31	Yes	Yes	13	4	6
113	B:B:H142	B:B:W169	19.3049	10.58	Yes	Yes	7	9	8
114	B:B:I157	B:B:W169	19.4117	3.52	No	Yes	0	7	8
115	B:B:I123	B:B:Y111	11.8014	6.04	Yes	Yes	0	6	4
116	B:B:I157	B:B:I171	10.3998	2.94	No	Yes	0	7	6
117	B:B:C148	B:B:L190	13.2064	6.35	No	No	0	6	5
118	B:B:L210	B:B:Q220	10.0367	6.65	No	Yes	0	5	7
119	B:B:L152	B:B:L192	10.641	4.15	Yes	No	0	3	5
120	B:B:L192	B:B:V158	10.7905	4.47	No	No	0	5	5
121	B:B:L190	B:B:V158	11.5025	4.47	No	No	0	5	5
122	B:B:L285	B:B:Y264	12.9038	4.69	No	Yes	0	6	5
123	B:B:A242	B:B:L285	11.1913	3.15	No	No	0	4	6
124	B:B:A242	B:B:F278	10.3341	4.16	No	Yes	0	4	7
125	B:B:D254	B:B:L261	47.3267	4.07	Yes	No	0	9	5
126	B:B:L252	B:B:L261	47.8628	4.15	No	No	0	7	5
127	B:B:L252	B:B:Y264	48.5276	3.52	No	Yes	0	7	5
128	B:B:M325	G:G:P49	24.8478	5.03	No	No	0	5	7
129	R:R:H223	R:R:N220	65.8371	3.83	No	Yes	0	9	9
130	R:R:E302	R:R:H223	65.4452	8.62	No	No	0	9	9
131	R:R:E302	R:R:L226	61.2198	7.95	No	No	0	9	9
132	R:R:L226	R:R:W298	26.6833	7.97	No	Yes	0	9	9
133	R:R:W298	R:R:W329	22.3297	10.31	Yes	Yes	5	9	9
134	R:R:T294	R:R:W329	20.2788	3.64	No	Yes	5	8	9
135	R:R:P332	R:R:T294	14.6083	6.99	Yes	No	5	9	8
136	R:R:F335	R:R:P332	10.8145	5.78	Yes	Yes	5	5	9
137	R:R:F230	R:R:L226	35.4388	4.87	Yes	No	0	8	9
138	R:R:F230	R:R:N295	24.075	13.29	Yes	No	0	8	8
139	R:R:N295	R:R:R233	24.578	13.26	No	Yes	0	8	8
140	R:R:F230	R:R:Q451	10.105	10.54	Yes	No	0	8	9
141	B:B:D323	B:B:M325	25.2548	13.86	Yes	No	0	7	5
142	B:B:W332	B:B:Y59	71.1701	5.79	Yes	Yes	2	9	8
143	B:B:M101	B:B:Y145	69.3924	3.59	Yes	Yes	0	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:S1	R:R:Q364	4.33	0	No	No	0	7	0	1
L:L:V2	R:R:L292	4.47	8	Yes	Yes	0	6	0	1
L:L:V2	R:R:Y296	5.05	8	Yes	Yes	0	7	0	1
L:L:V2	R:R:Y421	10.09	8	Yes	Yes	0	8	0	1
L:L:S3	R:R:Y191	3.82	0	No	Yes	0	7	0	1
L:L:S3	R:R:E444	8.62	0	No	Yes	0	7	0	1
L:L:E4	R:R:Y195	4.49	0	No	Yes	0	7	0	1
L:L:E4	R:R:I237	12.3	0	No	No	0	7	0	1
L:L:E4	R:R:L292	7.95	0	No	Yes	0	6	0	1
R:R:Y191	R:R:Y195	17.87	8	Yes	Yes	7	7	1	1
R:R:M445	R:R:Y191	16.76	0	No	Yes	6	7	2	1
R:R:N448	R:R:Y191	6.98	8	Yes	Yes	6	7	2	1
R:R:R233	R:R:Y195	11.32	8	Yes	Yes	8	7	2	1
R:R:A234	R:R:Y195	4	0	No	Yes	8	7	2	1
R:R:N448	R:R:Y195	5.81	8	Yes	Yes	6	7	2	1
R:R:L292	R:R:R233	6.07	8	Yes	Yes	6	8	1	2
R:R:R233	R:R:Y296	5.14	8	Yes	Yes	8	7	2	1
R:R:N448	R:R:R233	3.62	8	Yes	Yes	6	8	2	2
R:R:F288	R:R:I237	5.02	0	No	No	7	7	2	1
R:R:L292	R:R:Y296	4.69	8	Yes	Yes	6	7	1	1
R:R:I367	R:R:Y296	4.84	0	No	Yes	7	7	2	1
R:R:I371	R:R:Y296	4.84	8	No	Yes	7	7	2	1
R:R:Y296	R:R:Y421	15.89	8	Yes	Yes	7	8	1	1
R:R:Q364	R:R:W361	13.14	0	No	No	7	8	1	2
R:R:L368	R:R:Q364	9.32	0	No	No	4	7	2	1
R:R:I371	R:R:Y421	16.92	8	No	Yes	7	8	2	1
R:R:E444	R:R:Y421	7.86	0	Yes	Yes	7	8	1	1
R:R:E444	R:R:F424	7	0	Yes	No	7	7	1	2
R:R:E444	R:R:N448	3.94	0	Yes	Yes	7	6	1	2
L:L:I5	R:R:K360	1.45	0	No	No	0	7	0	1
R:R:K359	R:R:K360	1.44	0	No	No	3	7	2	1
R:R:E444	R:R:H442	1.23	0	Yes	No	7	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
33.33	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
30.77	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
30.43	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
29.63	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
29.17	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
29.17	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
28.00	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
28.00	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
27.78	Single	8XJN	Cloprosetnol	8XJN-TP-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
26.92	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
26.92	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
26.92	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
26.32	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
26.32	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
26.32	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
26.32	Consensus	tp_on	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
26.32	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
26.09	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
26.09	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
26.09	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
26.09	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
26.09	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
25.93	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
25.00	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
25.00	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
25.00	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
25.00	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
24.14	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
24.14	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
24.00	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
24.00	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
24.00	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
24.00	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
24.00	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
24.00	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
23.53	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
23.53	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
23.53	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
23.53	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
23.53	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
23.53	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
23.53	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
23.53	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
23.53	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
23.53	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
23.53	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
23.33	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
23.08	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
23.08	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
23.08	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
22.73	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
22.73	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
22.22	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
22.22	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
22.22	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
22.22	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
22.22	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
22.22	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
22.22	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
22.22	Single	7P2L	4YI	7P2L-mGlu₅-4YI
22.22	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
22.22	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
22.22	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
22.22	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
22.22	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
22.22	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
22.22	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
22.22	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
22.22	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
22.22	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
22.22	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
21.74	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
21.43	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
21.43	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
21.43	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
21.21	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
21.05	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
21.05	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
21.05	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
21.05	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
21.05	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
21.05	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
20.83	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
20.83	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
20.83	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
20.83	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
20.69	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
20.00	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
20.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
20.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
20.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
20.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
20.00	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
20.00	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
20.00	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
20.00	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
20.00	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
20.00	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
20.00	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
20.00	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
20.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
19.35	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
19.35	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
19.35	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
19.35	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
19.35	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
19.23	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
19.23	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
19.23	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
19.23	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
19.23	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
19.05	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
19.05	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
18.75	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
18.75	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
18.75	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
18.75	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
18.52	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
18.52	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
18.52	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
18.52	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
18.52	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
18.52	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
18.52	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
18.52	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
18.52	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
18.18	Single	7QA8	Peptide	7QA8-STE2-Peptide
18.18	Single	7QA8	Peptide	7QA8-STE2-Peptide
18.18	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
17.86	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
17.86	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
17.86	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
17.86	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
17.86	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
17.65	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
17.65	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
17.65	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
17.65	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
17.65	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
17.65	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
17.65	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
17.65	Single	8T1W	CVN424	8T1W-GPR6-CVN424
17.65	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
17.65	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
17.65	Consensus	histamine_off	Orthosteric Ligand	h1_off
17.65	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
17.24	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
17.14	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
16.67	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
16.67	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
16.67	Single	6PS6	Timolol	6PS6-β₂-Timolol
16.67	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
16.67	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
16.67	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
16.67	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
16.67	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
16.67	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
16.67	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
16.67	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
16.67	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
16.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
16.67	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
16.67	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
16.67	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
16.67	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
16.67	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
16.67	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
16.67	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
16.13	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
16.00	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
16.00	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
16.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
15.79	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
15.79	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
15.79	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
15.79	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
15.79	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
15.79	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
15.79	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
15.79	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
15.79	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
15.79	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
15.79	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
15.79	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
15.79	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
15.79	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
15.79	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
15.79	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
15.62	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
15.38	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
15.38	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
15.38	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
15.38	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
15.38	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
15.15	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
15.00	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
15.00	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
15.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
15.00	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
15.00	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
15.00	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
15.00	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
15.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
15.00	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
15.00	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
15.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
15.00	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
15.00	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
15.00	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
15.00	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
15.00	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
15.00	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
15.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
15.00	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
14.81	Single	6FJ3	PTH	6FJ3-PTH1-PTH
14.81	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
14.29	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
14.29	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
14.29	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
14.29	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
14.29	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
14.29	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
14.29	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
14.29	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
14.29	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
14.29	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
14.29	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
14.29	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
14.29	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
14.29	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
14.29	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
14.29	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
14.29	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
14.29	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
14.29	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
13.79	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
13.79	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
13.64	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
13.64	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
13.64	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
13.64	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
13.64	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
13.64	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
13.64	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
13.64	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
13.64	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
13.64	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
13.64	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
13.33	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
13.33	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
13.33	Single	6LI0	C17	6LI0-GPR52-C17
13.33	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
13.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
13.33	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
13.33	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
13.33	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
13.33	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
13.33	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
13.33	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
13.33	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
13.33	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
13.33	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go1/β1/γ2
13.33	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
13.33	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
13.33	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
13.04	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
13.04	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
13.04	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
12.90	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
12.50	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
12.50	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
12.50	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
12.50	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
12.50	Single	5U09	Taranabant	5U09-CB₁-Taranabant
12.50	Single	6AKX	A4R	6AKX-CCR5-A4R
12.50	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
12.50	Single	6B73	MP1104	6B73-κ-MP1104
12.50	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
12.50	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
12.50	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
12.50	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
12.50	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
12.50	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
12.50	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
12.50	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
12.50	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
12.50	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
12.50	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
12.50	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
12.50	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
12.50	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
12.50	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
12.50	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
12.50	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
12.50	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
12.50	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
12.50	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
12.50	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
12.50	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ
12.50	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
12.50	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
12.50	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
12.50	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
12.50	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
12.50	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
12.50	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
12.50	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
12.00	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
12.00	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
12.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
12.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
11.76	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
11.76	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
11.76	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
11.76	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
11.76	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
11.76	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
11.76	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
11.76	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
11.76	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
11.76	Single	6TPK	Retosiban	6TPK-OT-Retosiban
11.76	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
11.76	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
11.76	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
11.76	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
11.76	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
11.76	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
11.76	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
11.76	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
11.76	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
11.76	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
11.76	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
11.76	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
11.76	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
11.76	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
11.76	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
11.76	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
11.76	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
11.76	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
11.76	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
11.76	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
11.76	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
11.76	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
11.76	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
11.76	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
11.76	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
11.76	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
11.76	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
11.76	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
11.76	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
11.76	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
11.76	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
11.76	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
11.76	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
11.76	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
11.76	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
11.76	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
11.76	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
11.76	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
11.76	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
11.76	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
11.76	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
11.76	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
11.54	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
11.54	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
11.54	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
11.54	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
11.11	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
11.11	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
11.11	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
11.11	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
11.11	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
11.11	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
11.11	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
11.11	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
11.11	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
11.11	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
11.11	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
11.11	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
11.11	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
11.11	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
11.11	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
11.11	Single	6IIV	Daltroban	6IIV-TP-Daltroban
11.11	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
11.11	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
11.11	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
11.11	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
11.11	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
11.11	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
11.11	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
11.11	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
11.11	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
11.11	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
11.11	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
11.11	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
11.11	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.11	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
11.11	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
11.11	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
11.11	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
11.11	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
11.11	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
11.11	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
11.11	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
11.11	Single	8JXR	LSD	8JXR-D₁-LSD
11.11	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
11.11	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
11.11	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
11.11	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
11.11	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
11.11	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
11.11	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
11.11	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
11.11	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
11.11	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
11.11	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
11.11	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
11.11	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
11.11	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
11.11	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
11.11	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
11.11	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
11.11	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
11.11	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
11.11	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
11.11	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
11.11	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
11.11	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
11.11	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
11.11	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
11.11	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.11	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.11	Consensus	blt_on	Orthosteric Ligand	blt1_on
11.11	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
11.11	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
11.11	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
11.11	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
11.11	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
11.11	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
11.11	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
11.11	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
11.11	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
11.11	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
11.11	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
11.11	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
10.53	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
10.53	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
10.53	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
10.53	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
10.53	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
10.53	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-PubChem 129318963
10.53	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
10.53	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
10.53	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
10.53	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
10.53	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
10.53	Single	7C4S	S1P	7C4S-S1P₃-S1P
10.53	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
10.53	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
10.53	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
10.53	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
10.53	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
10.53	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
10.53	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
10.53	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
10.53	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
10.53	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
10.53	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
10.53	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
10.53	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
10.53	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
10.53	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
10.53	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go1/β1/γ2
10.53	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
10.53	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
10.53	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
10.53	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go1/β1/γ2
10.53	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
10.53	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
10.53	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
10.53	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
10.53	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
10.53	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
10.53	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
10.53	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
10.53	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
10.53	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
10.53	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
10.53	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
10.53	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
10.53	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
10.53	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
10.53	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
10.53	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
10.53	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.53	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.53	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
10.53	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.53	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
10.00	Single	2YDV	NECA	2YDV-A_2A-NECA
10.00	Single	4DJH	JDTic	4DJH-κ-JDTic
10.00	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
10.00	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
10.00	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
10.00	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
10.00	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
10.00	Single	5G53	NECA	5G53-A_2A-NECA-Gs
10.00	Single	5XR8	AM841	5XR8-CB₁-AM841
10.00	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
10.00	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
10.00	Single	6E59	L-760735	6E59-NK₁-L-760735
10.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
10.00	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
10.00	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
10.00	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
10.00	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
10.00	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
10.00	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
10.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
10.00	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
10.00	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
10.00	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
10.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
10.00	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
10.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
10.00	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
10.00	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
10.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
10.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
10.00	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
10.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
10.00	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
10.00	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
10.00	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
10.00	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
10.00	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
10.00	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
10.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
10.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
10.00	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
10.00	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
10.00	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
10.00	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
10.00	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
10.00	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
10.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
10.00	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
10.00	Consensus	a2_on	Orthosteric Ligand	a2b_on
10.00	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
10.00	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.00	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.00	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
10.00	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
10.00	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
10.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
10.00	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
10.00	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
10.00	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
10.00	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
10.00	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
10.00	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
10.00	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
9.52	Single	3D4S	Timolol	3D4S-β₂-Timolol
9.52	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
9.52	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
9.52	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
9.52	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
9.52	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
9.52	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
9.52	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
9.52	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
9.52	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
9.52	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
9.52	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
9.52	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
9.52	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
9.52	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
9.52	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
9.52	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
9.52	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
9.52	Single	8JWY	2-118	8JWY-A_2A-2-118
9.52	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
9.52	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
9.52	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
9.52	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
9.52	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
9.52	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
9.52	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
9.52	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
9.52	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
9.52	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
9.52	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
9.52	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
9.52	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
9.52	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
9.52	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
9.52	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
9.52	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
9.52	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
9.52	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
9.52	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
9.09	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
9.09	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
9.09	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
9.09	Single	5X93	K-8794	5X93-ET_B-K-8794
9.09	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
9.09	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
9.09	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
9.09	Single	7EZC	UKA	7EZC-A_2A-UKA
9.09	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
9.09	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
9.09	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
9.09	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
9.09	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
9.09	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
9.09	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
9.09	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
9.09	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
9.09	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
9.09	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
9.09	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
9.09	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
9.09	Consensus	endothelin_off	Orthosteric Ligand	etb_off
9.09	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
9.09	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
9.09	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
9.09	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
8.70	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
8.70	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
8.70	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
8.70	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
8.70	Single	6PT3	DPI-287	6PT3-δ-DPI-287
8.70	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
8.70	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
8.70	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
8.70	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
8.70	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
8.70	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
8.70	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
8.70	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
8.33	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
8.33	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
8.33	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
8.33	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
8.33	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
8.33	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
8.33	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
8.33	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
8.33	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
8.33	Single	8GEJ	Constrained Epinephrine	8GEJ-β₂-Constrained Epinephrine-Gs/β1/γ2
8.33	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
8.33	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
8.33	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
8.33	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
8.33	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
8.33	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
8.33	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
8.33	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
8.33	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
8.33	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
8.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
8.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
8.00	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
8.00	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
8.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
8.00	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
8.00	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
8.00	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
7.69	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
7.69	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
7.69	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
7.69	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
7.69	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
7.69	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
7.69	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
7.69	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
7.69	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
7.69	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
7.69	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
7.41	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
7.41	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
7.41	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
7.41	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
7.41	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
7.41	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
7.41	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
7.41	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
7.41	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
7.14	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
7.14	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
7.14	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
7.14	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
7.14	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
7.14	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
7.14	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
7.14	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
7.14	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
7.14	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
7.14	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
7.14	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
7.14	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
7.14	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
7.14	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
7.14	Consensus	sensory_on	Orthosteric Ligand	opsins_on
6.90	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
6.67	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
6.67	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
6.67	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
6.67	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
6.67	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
6.67	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
6.67	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.67	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
6.67	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
6.67	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
6.67	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
6.67	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
6.67	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
6.67	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
6.67	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
6.67	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
6.67	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.67	Single	8GH1	Constrained Epinephrine	8GH1-β₂-Constrained Epinephrine
6.67	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
6.67	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
6.67	Single	8J6Q	Compound 9n	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
6.67	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
6.67	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
6.67	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
6.67	Consensus	5ht2_on	Orthosteric Ligand	5ht2b_on
6.67	Consensus	5ht2b_on	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
6.67	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
6.67	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
6.67	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
6.67	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
6.67	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
6.67	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
6.67	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
6.67	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
6.45	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
6.45	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
6.25	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
6.25	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
6.25	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
6.25	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
6.25	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
6.25	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
6.25	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
6.25	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
6.25	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
6.25	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
6.25	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
6.25	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
6.25	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
6.25	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
6.25	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
6.25	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
6.25	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
6.25	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
6.25	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
6.25	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
6.25	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/β1/γ2
6.25	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
6.25	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
6.25	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
6.25	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
6.25	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
6.25	Single	8UO4	Constrained Epinephrine	8UO4-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
6.25	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
6.25	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
6.25	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
6.25	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
6.25	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go1/β1/γ2
6.25	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
6.25	Single	9B9Y	7DY	9B9Y-CB₁-7DY
6.25	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
6.25	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
6.25	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
6.25	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
6.25	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
6.25	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
6.25	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
6.25	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
6.25	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
6.25	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
6.25	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.88	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
5.88	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
5.88	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
5.88	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
5.88	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
5.88	Single	4XNV	BPTU	4XNV-P2Y₁-BPTU
5.88	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
5.88	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
5.88	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
5.88	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
5.88	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
5.88	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
5.88	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
5.88	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
5.88	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
5.88	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
5.88	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
5.88	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
5.88	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
5.88	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
5.88	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
5.88	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
5.88	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
5.88	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
5.88	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
5.88	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.88	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
5.88	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
5.88	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
5.88	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
5.88	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
5.88	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
5.88	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
5.88	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
5.88	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
5.88	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
5.88	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
5.88	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
5.88	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
5.88	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
5.88	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
5.88	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
5.88	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
5.88	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
5.88	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
5.88	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
5.88	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
5.88	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
5.88	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
5.88	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
5.88	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
5.88	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
5.88	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
5.88	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
5.88	Consensus	5ht2_on_gp	Orthosteric Ligand	5ht2b_on_gp
5.88	Consensus	5ht2b_on_gp	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
5.88	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
5.88	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
5.88	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
5.88	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
5.88	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
5.88	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
5.88	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.88	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
5.88	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
5.88	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.88	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
5.88	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
5.88	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
5.88	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
5.88	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
5.88	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
5.88	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
5.88	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
5.88	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
5.88	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
5.88	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
5.56	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
5.56	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
5.56	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
5.56	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
5.56	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
5.56	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
5.56	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
5.56	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
5.56	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
5.56	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
5.56	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
5.56	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
5.56	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
5.56	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
5.56	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
5.56	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
5.56	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
5.56	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
5.56	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
5.56	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
5.56	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
5.56	Single	6TPG	EMPA	6TPG-OX₂-EMPA
5.56	Single	6VI4	JDTic	6VI4-κ-JDTic
5.56	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
5.56	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
5.56	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
5.56	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.56	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.56	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
5.56	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
5.56	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
5.56	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
5.56	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
5.56	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
5.56	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
5.56	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
5.56	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.56	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
5.56	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
5.56	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
5.56	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
5.56	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
5.56	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
5.56	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
5.56	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
5.56	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
5.56	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
5.56	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
5.56	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
5.56	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
5.56	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.56	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
5.56	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
5.56	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
5.56	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
5.56	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
5.56	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
5.56	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
5.56	Single	8K9L	Damgo	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
5.56	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
5.56	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
5.56	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
5.56	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
5.56	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
5.56	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
5.56	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
5.56	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go1/β1/γ2
5.56	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070-Cholesterol
5.56	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
5.56	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
5.56	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
5.56	Consensus	a2_off	Orthosteric Ligand	a2a_off
5.56	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
5.56	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
5.56	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
5.56	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
5.56	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.56	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.56	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.56	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
5.56	Consensus	hca_on	Orthosteric Ligand	hca2_on
5.56	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
5.56	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
5.56	Consensus	sensory_off	Orthosteric Ligand	opsins_off
5.41	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.41	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.26	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
5.26	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
5.26	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
5.26	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
5.26	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
5.26	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
5.26	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
5.26	Single	4QKX	35V	4QKX-β₂-35V
5.26	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
5.26	Single	5DHG	C-35	5DHG-NOP-C-35
5.26	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
5.26	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
5.26	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
5.26	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
5.26	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
5.26	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
5.26	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
5.26	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
5.26	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
5.26	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
5.26	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
5.26	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
5.26	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
5.26	Single	6PS1	Timolol	6PS1-β₂-Timolol
5.26	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
5.26	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
5.26	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
5.26	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
5.26	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
5.26	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
5.26	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
5.26	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
5.26	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
5.26	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.26	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
5.26	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
5.26	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
5.26	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
5.26	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
5.26	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
5.26	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
5.26	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
5.26	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
5.26	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
5.26	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
5.26	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
5.26	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
5.26	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
5.26	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
5.26	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
5.26	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
5.26	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
5.26	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
5.26	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
5.26	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
5.26	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
5.26	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
5.26	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
5.26	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
5.26	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
5.26	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
5.26	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
5.26	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.26	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.26	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
5.26	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
5.26	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
5.26	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
5.26	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
5.26	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
5.26	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
5.26	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
5.26	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
5.26	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
5.26	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
5.26	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
5.26	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
5.26	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
5.26	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
5.26	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.26	Consensus	a3_on	Orthosteric Ligand	a3a_on
5.26	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
5.26	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
5.26	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
5.26	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.26	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
5.26	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
5.26	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.26	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
5.26	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
5.26	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.26	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
5.26	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
5.00	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
5.00	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
5.00	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
5.00	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
5.00	Single	5C1M	BU72	5C1M-μ-BU72
5.00	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
5.00	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
5.00	Single	5N2S	PSB36	5N2S-A₁-PSB36
5.00	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
5.00	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
5.00	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
5.00	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
5.00	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
5.00	Single	5WQC	EMPA	5WQC-OX₂-EMPA
5.00	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
5.00	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
5.00	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
5.00	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
5.00	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
5.00	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
5.00	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
5.00	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
5.00	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
5.00	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
5.00	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
5.00	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
5.00	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
5.00	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
5.00	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
5.00	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
5.00	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
5.00	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
5.00	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
5.00	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
5.00	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
5.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
5.00	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/β1/γ2
5.00	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
5.00	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
5.00	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
5.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
5.00	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
5.00	Single	7W41	PD176252	7W41-BB₂-PD176252
5.00	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
5.00	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
5.00	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
5.00	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
5.00	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
5.00	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
5.00	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
5.00	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
5.00	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
5.00	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
5.00	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
5.00	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
5.00	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
5.00	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
5.00	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
5.00	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
5.00	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
5.00	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
5.00	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.00	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
5.00	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
5.00	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.00	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
5.00	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
5.00	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
5.00	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
5.00	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
5.00	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
5.00	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
5.00	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
5.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
5.00	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
5.00	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.00	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.00	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.00	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
5.00	Consensus	ep_off	Orthosteric Ligand	ep4_off
5.00	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
5.00	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
5.00	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
5.00	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
5.00	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
4.76	Single	3P0G	BI167107	3P0G-β₂-BI167107
4.76	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
4.76	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
4.76	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
4.76	Single	5V56	TC114	5V56-SMO-TC114
4.76	Single	5V57	TC114	5V57-SMO-TC114
4.76	Single	5XRA	AM11542	5XRA-CB₁-AM11542
4.76	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
4.76	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
4.76	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
4.76	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
4.76	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
4.76	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
4.76	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
4.76	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
4.76	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
4.76	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
4.76	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
4.76	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
4.76	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
4.76	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
4.76	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
4.76	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
4.76	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
4.76	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
4.76	Single	8E0G	BU72	8E0G-μ-BU72
4.76	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
4.76	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
4.76	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
4.76	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
4.76	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
4.76	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.76	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
4.76	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
4.76	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
4.76	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
4.76	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
4.76	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
4.76	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.76	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
4.76	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
4.76	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go1/β1/γ2
4.76	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
4.76	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
4.76	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
4.76	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
4.76	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.76	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.76	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
4.76	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
4.76	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
4.76	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
4.76	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
4.76	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
4.76	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
4.76	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
4.65	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
4.55	Single	4LDE	BI167107	4LDE-β₂-BI167107
4.55	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
4.55	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
4.55	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
4.55	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
4.55	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.55	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
4.55	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
4.55	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
4.55	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
4.55	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
4.55	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.55	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.55	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
4.55	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.55	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
4.55	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
4.55	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
4.55	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
4.55	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
4.55	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
4.55	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
4.55	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
4.55	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
4.55	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
4.55	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
4.55	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
4.55	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
4.55	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.55	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
4.55	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
4.55	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.55	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.55	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
4.55	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
4.55	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.55	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.55	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
4.55	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
4.55	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.55	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
4.55	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.55	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
4.55	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
4.55	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
4.55	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
4.55	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
4.55	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	orexin_on	Orthosteric Ligand	ox2_on
4.55	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.55	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.35	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
4.35	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
4.35	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
4.35	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
4.35	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
4.35	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
4.35	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
4.35	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
4.35	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.35	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
4.35	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
4.35	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.35	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
4.35	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
4.35	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
4.35	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
4.35	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
4.35	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
4.35	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
4.35	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
4.35	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.35	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
4.35	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
4.35	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
4.35	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
4.35	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.35	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.35	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
4.35	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
4.35	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.35	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.35	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
4.35	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
4.35	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
4.35	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
4.17	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
4.17	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.17	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
4.17	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
4.17	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
4.17	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
4.17	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
4.17	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
4.17	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
4.17	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
4.17	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
4.17	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
4.17	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
4.17	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.17	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.17	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
4.17	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.17	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.00	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
4.00	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
4.00	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
4.00	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
4.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
4.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
4.00	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
4.00	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
4.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
4.00	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
4.00	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.00	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
4.00	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
4.00	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
4.00	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
4.00	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
4.00	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.00	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
4.00	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
4.00	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.00	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
4.00	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.00	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
4.00	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.00	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.00	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
4.00	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
4.00	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
4.00	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
4.00	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.00	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.00	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
4.00	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.85	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
3.85	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
3.85	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
3.85	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
3.85	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
3.85	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
3.85	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
3.85	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
3.85	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
3.85	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
3.85	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
3.85	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
3.85	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
3.85	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
3.85	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.85	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
3.85	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
3.85	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
3.85	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
3.85	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
3.85	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.85	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
3.85	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.85	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.85	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
3.85	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
3.85	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
3.85	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
3.70	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.70	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.70	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
3.70	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
3.70	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.70	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.70	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
3.70	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
3.70	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
3.70	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
3.70	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.70	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.70	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
3.70	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
3.70	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.70	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.70	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
3.70	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.70	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
3.70	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
3.70	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
3.57	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
3.57	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.57	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.57	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
3.57	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
3.57	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
3.57	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.57	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
3.57	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
3.57	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
3.57	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
3.57	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
3.57	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
3.57	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
3.57	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
3.57	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
3.45	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
3.45	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
3.45	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
3.45	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.45	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.45	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
3.45	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.45	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
3.45	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
3.45	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
3.45	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
3.45	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
3.45	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
3.45	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
3.45	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
3.45	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
3.45	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.45	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.33	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
3.33	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.33	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
3.33	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
3.33	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
3.33	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
3.33	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
3.33	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
3.33	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.33	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.33	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
3.33	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
3.23	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
3.23	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.23	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
3.23	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
3.23	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
3.23	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
3.23	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
3.23	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
3.23	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
3.23	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.23	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.23	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.23	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
3.23	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
3.12	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.12	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
3.12	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
3.12	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
3.12	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.12	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.12	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
3.12	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
3.12	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
3.12	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.12	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
3.12	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
3.03	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
3.03	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
3.03	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
3.03	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.03	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
3.03	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
2.94	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
2.94	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
2.94	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
2.94	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
2.94	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
2.86	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
2.78	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2

PDB Summary
PDB	7VVO
Class	B1
SubFamily	Peptide
Type	Parathyroid Hormone
SubType	PTH1
Species	Homo Sapiens
Ligand	PTH
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	4.1
Date	2022-08-03
D.O.I.	10.1016/j.molcel.2022.07.003

Net Summary
I_min	3.52
Number of Linked Nodes	871
Number of Links	1006
Number of Hubs	146
Number of Links mediated by Hubs	552
Number of Communities	29
Number of Nodes involved in Communities	187
Number of Links involved in Communities	259

Path Summary
Number Of Nodes in MetaPath	144
Number Of Links MetaPath	143
Number of Shortest Paths	940416
Length Of Smallest Path	3
Average Path Length	25.8796
Length of Longest Path	54
Minimum Path Strength	1.07
Average Path Strength	6.88731
Maximum Path Strength	18.8
Minimum Path Correlation	0.72
Average Path Correlation	0.993625
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	74.7793
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.4739
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • parathyroid hormone receptor binding • signaling receptor binding • G protein-coupled receptor binding • type 1 parathyroid hormone receptor binding • molecular transducer activity • molecular function activator activity • signaling receptor activity • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • peptide hormone receptor binding • hormone receptor binding • hormone activity • response to xenobiotic stimulus • response to parathyroid hormone • magnesium ion homeostasis • inorganic ion homeostasis • chemical homeostasis • homeostatic process • monoatomic ion homeostasis • monoatomic cation homeostasis • ossification • bone mineralization • biomineral tissue development • tissue development • multicellular organismal-level homeostasis • homeostasis of number of cells within a tissue • anatomical structure homeostasis • tissue homeostasis • homeostasis of number of cells • biosynthetic process • metabolic process • macromolecule metabolic process • macromolecule biosynthetic process • skeletal system development • regulation of biosynthetic process • positive regulation of biological process • regulation of macromolecule metabolic process • gene expression • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • positive regulation of macromolecule metabolic process • regulation of metabolic process • positive regulation of cellular process • RNA metabolic process • primary metabolic process • nucleobase-containing compound biosynthetic process • nucleic acid metabolic process • RNA biosynthetic process • nucleobase-containing compound metabolic process • DNA-templated transcription • nucleic acid biosynthetic process • transcription by RNA polymerase II • negative regulation of apoptotic process in bone marrow cell • negative regulation of programmed cell death • apoptotic process in bone marrow cell • regulation of apoptotic process in bone marrow cell • regulation of apoptotic process • negative regulation of biological process • regulation of programmed cell death • negative regulation of apoptotic process • negative regulation of cellular process • regulation of generation of precursor metabolites and energy • regulation of primary metabolic process • positive regulation of glycogen metabolic process • regulation of small molecule metabolic process • small molecule metabolic process • carbohydrate biosynthetic process • hexose metabolic process • positive regulation of glucose metabolic process • positive regulation of glycogen biosynthetic process • energy reserve metabolic process • positive regulation of carbohydrate metabolic process • regulation of glycogen metabolic process • monosaccharide metabolic process • regulation of glycogen biosynthetic process • glucan biosynthetic process • energy derivation by oxidation of organic compounds • regulation of glucan biosynthetic process • regulation of polysaccharide metabolic process • polysaccharide metabolic process • glucan metabolic process • regulation of carbohydrate metabolic process • regulation of glucose metabolic process • carbohydrate metabolic process • polysaccharide biosynthetic process • glycogen metabolic process • generation of precursor metabolites and energy • glycogen biosynthetic process • regulation of polysaccharide biosynthetic process • regulation of carbohydrate biosynthetic process • positive regulation of small molecule metabolic process • glucose metabolic process • phosphate ion homeostasis • cell-cell signaling • intracellular calcium ion homeostasis • calcium ion homeostasis • cellular homeostasis • intracellular monoatomic cation homeostasis • intracellular chemical homeostasis • intracellular monoatomic ion homeostasis • regulation of developmental process • regulation of biomineral tissue development • regulation of bone mineralization • positive regulation of ossification • positive regulation of developmental process • positive regulation of biomineral tissue development • regulation of multicellular organismal process • regulation of multicellular organismal development • positive regulation of bone mineralization • positive regulation of multicellular organismal process • regulation of ossification • response to ethanol • response to metal ion • response to lead ion • positive regulation of cell population proliferation • positive regulation of cell proliferation in bone marrow • cell proliferation in bone marrow • regulation of cell proliferation in bone marrow • regulation of cell population proliferation • response to nutrient levels • response to vitamin D • response to nutrient • response to vitamin • hormone-mediated signaling pathway • apoptotic signaling pathway • hormone-mediated apoptotic signaling pathway • nucleoside phosphate metabolic process • ribose phosphate metabolic process • cAMP metabolic process • cyclic purine nucleotide metabolic process • carbohydrate derivative metabolic process • nucleotide metabolic process • cyclic nucleotide metabolic process • purine-containing compound metabolic process • purine nucleotide metabolic process • ribonucleotide metabolic process • organophosphate metabolic process • nucleobase-containing small molecule metabolic process • phosphate-containing compound metabolic process • purine ribonucleotide metabolic process • phosphorus metabolic process • regulation of cartilage development • regulation of chondrocyte differentiation • connective tissue development • cellular developmental process • negative regulation of cartilage development • negative regulation of chondrocyte differentiation • regulation of cell differentiation • cell differentiation • negative regulation of cell differentiation • negative regulation of developmental process • chondrocyte differentiation • negative regulation of multicellular organismal process • cartilage development • negative regulation of metabolic process • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of macromolecule metabolic process • regulation of localization • hexose transmembrane transport • D-glucose import • transport • carbohydrate transport • positive regulation of D-glucose transmembrane transport • localization • positive regulation of transmembrane transport • regulation of D-glucose import • positive regulation of D-glucose import • regulation of transport • establishment of localization • transmembrane transport • regulation of transmembrane transport • positive regulation of transport • D-glucose transmembrane transport • regulation of D-glucose transmembrane transport • monosaccharide transmembrane transport • carbohydrate transmembrane transport • positive regulation of cell communication • regulation of signaling • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • regulation of response to stimulus • regulation of cell communication • positive regulation of signaling • response to cadmium ion • small GTPase-mediated signal transduction • Rho protein signal transduction • intracellular signal transduction • intracellular signaling cassette • regulation of leukocyte proliferation • osteoclast proliferation • regulation of osteoclast proliferation • positive regulation of osteoclast proliferation • leukocyte proliferation • positive regulation of leukocyte proliferation • bone maturation • regulation of bone mineralization involved in bone maturation • negative regulation of biomineral tissue development • negative regulation of bone mineralization • ossification involved in bone maturation • bone development • bone mineralization involved in bone maturation • developmental maturation • negative regulation of bone mineralization involved in bone maturation • negative regulation of ossification • anatomical structure maturation • animal organ maturation • positive regulation of DNA-templated transcription • regulation of RNA metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of transcription by RNA polymerase II • positive regulation of nucleobase-containing compound metabolic process • positive regulation of transcription by RNA polymerase II • positive regulation of RNA metabolic process • positive regulation of RNA biosynthetic process • regulation of DNA-templated transcription • regulation of inositol phosphate biosynthetic process • alcohol metabolic process • positive regulation of phosphate metabolic process • inositol phosphate metabolic process • regulation of phosphate metabolic process • polyol biosynthetic process • polyol metabolic process • positive regulation of phosphorus metabolic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • positive regulation of inositol phosphate biosynthetic process • organophosphate biosynthetic process • inositol phosphate biosynthetic process • alcohol biosynthetic process • regulation of phosphorus metabolic process • positive regulation of alcohol biosynthetic process • tissue remodeling • bone remodeling • bone resorption • response to fibroblast growth factor • response to growth factor • identical protein binding • protein homodimerization activity • protein dimerization activity • amide binding • peptide hormone binding • hormone binding • peptide receptor activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • transmembrane signaling receptor activity • parathyroid hormone receptor activity • osteoblast development • cell development • osteoblast differentiation • embryo development ending in birth or egg hatching • chordate embryonic development • embryo development • in utero embryonic development • cell maturation • cell surface receptor signaling pathway • negative regulation of cell population proliferation • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • apical part of cell • apical plasma membrane • basal part of cell • basal plasma membrane • basolateral plasma membrane • receptor complex
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>7VVO_Chain_A Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I V K Q M R I G I F E T K F Q V D K V N F H M F D V G G Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N L F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N A R R I F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>7VVO_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>7VVO_Chain_G A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q03431
Sequence	>7VVO_Chain_R T K E E Q I F L L H R A Q A Q C E K R L V V A V P C P D Y I Y D F N H K G H A Y R R C D R N G S W E L V P G H N R T W A N Y S E C V K F L R L G M I Y T V G Y S V S L A S L T V A V L I L A Y F R R L H C T R N Y I H M H L F L S F M L R A V S I F V K D A G C R V A V T F F L Y F L A T N Y Y W I L V E G L Y L H S L I F M A F F S E K K Y L W G F T V F G W G L P A V F V A V W V S V R A T L A N G N K K W I I Q V P I L A S I V L N F I L F I N I V R V L A T K L R E T D T R Q Q Y R K L L K S T L V L M P L F G V H Y I V F M A T P Y T E V H Y E M L F N S F Q G F F V A I I Y C F C N G E V Q A E I K K S W S R W Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9JR3	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.8	2024-10-16	To be published
	9JR3 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.8	2024-10-16	To be published
	9JR2	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.8	2024-10-16	To be published
	9JR2 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.8	2024-10-16	To be published
	8JR9	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	PCO371	chim(NtGi1-Gs)/β1/γ2	2.57	2023-08-02	10.1038/s41586-023-06467-w
	8JR9 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	PCO371		2.57	2023-08-02	10.1038/s41586-023-06467-w
	7Y36	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Teriparatide	-	Gs/β1/γ2	2.8	2023-07-05	To be published
	7Y36 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Teriparatide	-		2.8	2023-07-05	To be published
	7Y35	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/β1/γ2	2.9	2023-07-05	To be published
	7Y35 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-		2.9	2023-07-05	To be published
	8GW8	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	KHF	Gs/β1/γ2	2.9	2023-06-14	10.1038/s41586-023-06169-3
	8GW8 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	KHF		2.9	2023-06-14	10.1038/s41586-023-06169-3
	8FLU	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH	-	Gs/β1/γ2	2.76	2023-04-26	10.1016/j.str.2023.04.002
	8FLU (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH	-		2.76	2023-04-26	10.1016/j.str.2023.04.002
	8FLT	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	M-PTH(1-14)	-	Gs/β1/γ2	3.03	2023-04-26	10.1016/j.str.2023.04.002
	8FLT (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	M-PTH(1-14)	-		3.03	2023-04-26	10.1016/j.str.2023.04.002
	8FLS	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/β1/γ2	3.09	2023-04-26	10.1016/j.str.2023.04.002
	8FLS (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-		3.09	2023-04-26	10.1016/j.str.2023.04.002
	8FLR	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/β1/γ2	2.94	2023-04-26	10.1016/j.str.2023.04.002
	8FLR (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-		2.94	2023-04-26	10.1016/j.str.2023.04.002
	8FLQ	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	2.55	2023-04-26	10.1016/j.str.2023.04.002
	8FLQ (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.55	2023-04-26	10.1016/j.str.2023.04.002
	8HAO	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/β1/γ2	3.76	2022-12-21	10.1038/s41401-022-01032-z
	8HAO (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.76	2022-12-21	10.1038/s41401-022-01032-z
	8HAF	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	chim(NtGi1-Gs)/β1/γ2	3.25	2022-12-21	10.1038/s41401-022-01032-z
	8HAF (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-		3.25	2022-12-21	10.1038/s41401-022-01032-z
	8HA0	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/β1/γ2	2.62	2022-12-21	10.1038/s41401-022-01032-z
	8HA0 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.62	2022-12-21	10.1038/s41401-022-01032-z
	7VVO	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	4.1	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVO (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		4.1	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVN	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	3.8	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVN (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.8	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVM	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	3.2	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVM (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.2	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVL	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	2.8	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVL (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.8	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVK	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	3.3	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVK (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.3	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVJ	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/β1/γ2	3.2	2022-08-03	10.1016/j.molcel.2022.07.003
	7VVJ (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-		3.2	2022-08-03	10.1016/j.molcel.2022.07.003
	6NBI	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-	Gs/β1/γ2	4	2019-04-17	10.1126/science.aav7942
	6NBI (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-		4	2019-04-17	10.1126/science.aav7942
	6NBH	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-	Gs/β1/γ2	3.5	2019-04-17	10.1126/science.aav7942
	6NBH (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-		3.5	2019-04-17	10.1126/science.aav7942
	6NBF	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-	Gs/β1/γ2	3	2019-04-17	10.1126/science.aav7942
	6NBF (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-		3	2019-04-17	10.1126/science.aav7942
	6FJ3	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	-	2.5	2018-11-21	10.1038/s41594-018-0151-4

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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