psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D16	A:A:E15	9.09	No	No	0	4	6
2	A:A:A19	A:A:D16	3.09	No	No	0	4	4
3	A:A:D16	B:B:T86	5.78	No	No	0	4	6
4	A:A:A19	B:B:N88	3.13	No	Yes	0	4	7
5	A:A:V20	B:B:N88	5.91	No	Yes	0	3	7
6	A:A:S23	B:B:N88	8.94	No	Yes	0	7	7
7	A:A:S23	B:B:K89	3.06	No	Yes	0	7	9
8	A:A:I26	B:B:K89	5.82	No	Yes	0	9	9
9	A:A:I26	B:B:A92	3.25	No	No	0	9	6
10	A:A:E27	B:B:K89	8.1	No	Yes	0	6	9
11	A:A:K34	A:A:Q31	9.49	No	No	0	4	4
12	A:A:D33	B:B:D76	11.98	No	Yes	0	5	9
13	A:A:K34	B:B:L55	2.82	No	No	0	4	6
14	A:A:R42	A:A:Y37	6.17	No	No	0	9	4
15	A:A:Y37	B:B:L55	4.69	No	No	17	4	6
16	A:A:Y37	B:B:D76	5.75	No	Yes	17	4	9
17	A:A:R38	R:R:E668	9.3	No	No	0	4	8
18	A:A:N218	A:A:T40	5.85	No	No	0	4	7
19	A:A:H220	A:A:T40	2.74	Yes	No	0	7	7
20	A:A:H41	A:A:T242	6.85	No	No	0	6	8
21	A:A:H41	R:R:F665	4.53	No	Yes	0	6	8
22	A:A:F219	A:A:L43	2.44	Yes	No	0	8	7
23	A:A:I245	A:A:L43	7.14	No	No	0	7	7
24	A:A:L44	A:A:L46	6.92	No	No	18	9	8
25	A:A:I244	A:A:L44	2.85	No	No	18	8	9
26	A:A:K53	A:A:L45	4.23	Yes	Yes	19	9	8
27	A:A:L45	A:A:M221	2.83	Yes	No	0	8	8
28	A:A:L45	A:A:V247	2.98	Yes	No	19	8	7
29	A:A:I244	A:A:L46	2.85	No	No	18	8	8
30	A:A:A48	A:A:R265	2.77	No	No	0	8	9
31	A:A:D49	A:A:N50	9.42	No	No	0	6	4
32	A:A:K53	A:A:S51	7.65	Yes	No	0	9	9
33	A:A:G52	A:A:K53	3.49	No	Yes	0	9	9
34	A:A:G52	A:A:N292	3.39	No	Yes	0	9	9
35	A:A:K53	A:A:V247	4.55	Yes	No	19	9	7
36	A:A:I56	A:A:N292	2.83	No	Yes	0	7	9
37	A:A:T210	A:A:V57	4.76	No	No	0	7	7
38	A:A:F212	A:A:Q59	4.68	No	No	0	9	9
39	A:A:G206	B:B:N119	5.09	No	No	0	8	9
40	A:A:E209	A:A:I207	4.1	No	Yes	1	9	9
41	A:A:F222	A:A:I207	2.51	Yes	Yes	1	7	9
42	A:A:I207	A:A:V224	3.07	Yes	Yes	1	9	9
43	A:A:I207	B:B:L117	2.85	Yes	No	0	9	9
44	A:A:D223	A:A:F208	4.78	No	No	0	9	5
45	A:A:E209	A:A:H220	2.46	No	Yes	1	9	7
46	A:A:E209	A:A:F222	13.99	No	Yes	1	9	7
47	A:A:M221	A:A:T210	6.02	No	No	0	8	7
48	A:A:H220	A:A:K211	5.24	Yes	No	0	7	4
49	A:A:F212	A:A:V214	2.62	No	Yes	7	9	6
50	A:A:F212	A:A:F219	9.65	No	Yes	7	9	8
51	A:A:N218	A:A:Q213	9.24	No	No	0	4	3
52	A:A:D215	A:A:V214	4.38	No	Yes	0	5	6
53	A:A:F219	A:A:V214	2.62	Yes	Yes	7	8	6
54	A:A:A372	A:A:V214	5.09	No	Yes	0	8	6
55	A:A:D215	A:A:F376	9.55	No	Yes	0	5	8
56	A:A:F219	A:A:V217	2.62	Yes	No	7	8	5
57	A:A:F376	A:A:V217	2.62	Yes	No	7	8	5
58	A:A:V217	R:R:F665	7.87	No	Yes	7	5	8
59	A:A:F219	A:A:I375	3.77	Yes	No	0	8	9
60	A:A:C379	A:A:F219	4.19	No	Yes	0	8	8
61	A:A:F222	A:A:H220	7.92	Yes	Yes	1	7	7
62	A:A:F222	B:B:S98	2.64	Yes	No	1	7	8
63	A:A:F222	B:B:W99	10.02	Yes	Yes	1	7	9
64	A:A:Q227	A:A:V224	7.16	No	Yes	1	9	9
65	A:A:V224	A:A:W234	3.68	Yes	Yes	1	9	9
66	A:A:Q227	A:A:W234	8.76	No	Yes	1	9	9
67	A:A:E230	A:A:R232	12.79	No	No	0	9	8
68	A:A:R231	A:A:W234	4	No	Yes	0	9	9
69	A:A:D272	A:A:R231	2.38	No	No	0	8	9
70	A:A:I276	A:A:R231	5.01	No	No	0	8	9
71	A:A:R232	A:A:S275	5.27	No	No	0	8	8
72	A:A:K233	B:B:Y145	11.94	Yes	Yes	14	9	8
73	A:A:K233	B:B:D186	13.83	Yes	No	14	9	9
74	A:A:K233	B:B:M188	12.96	Yes	No	0	9	8
75	A:A:K233	B:B:C204	6.47	Yes	No	0	9	7
76	A:A:F238	A:A:W234	4.01	No	Yes	1	9	9
77	A:A:I235	A:A:L282	4.28	No	Yes	0	9	9
78	A:A:Q236	A:A:W281	21.9	No	No	0	8	5
79	A:A:C237	A:A:F238	9.78	No	No	1	8	9
80	A:A:C237	B:B:Y59	2.69	No	Yes	1	8	8
81	A:A:C237	B:B:W99	2.61	No	Yes	1	8	9
82	A:A:F238	B:B:W99	9.02	No	Yes	1	9	9
83	A:A:D240	B:B:K57	9.68	No	Yes	0	6	9
84	A:A:I285	A:A:V241	3.07	No	No	0	7	9
85	A:A:A243	A:A:I288	3.25	No	No	0	8	9
86	A:A:F246	A:A:V248	2.62	Yes	No	0	9	7
87	A:A:D272	A:A:F246	4.78	No	Yes	0	8	9
88	A:A:F246	A:A:F273	4.29	Yes	No	0	9	9
89	A:A:F246	A:A:L289	3.65	Yes	No	0	9	9
90	A:A:F345	A:A:V248	9.18	Yes	No	0	8	7
91	A:A:D249	A:A:S261	10.31	No	No	0	8	4
92	A:A:D249	A:A:D262	9.31	No	No	0	8	4
93	A:A:L291	A:A:S260	3	No	No	0	8	8
94	A:A:K293	A:A:S261	6.12	No	No	20	9	4
95	A:A:L296	A:A:S261	4.5	Yes	No	20	6	4
96	A:A:D262	A:A:R265	8.34	No	No	0	4	9
97	A:A:K300	A:A:Y263	13.14	No	Yes	21	9	6
98	A:A:V301	A:A:Y263	3.79	No	Yes	0	7	6
99	A:A:S306	A:A:Y263	6.36	No	Yes	21	7	6
100	A:A:I308	A:A:Y263	3.63	No	Yes	0	7	6
101	A:A:N264	A:A:Y311	12.79	No	No	0	9	6
102	A:A:F345	A:A:L270	3.65	Yes	No	0	8	6
103	A:A:I348	A:A:L270	4.28	No	No	0	4	6
104	A:A:K274	A:A:N271	5.6	No	No	0	5	5
105	A:A:F273	A:A:V287	3.93	No	No	0	9	6
106	A:A:I348	A:A:K274	4.36	No	No	0	4	5
107	A:A:I276	A:A:S275	4.64	No	No	0	8	8
108	A:A:V287	A:A:W277	2.45	No	Yes	10	6	6
109	A:A:S349	A:A:W277	3.71	No	Yes	10	7	6
110	A:A:S352	A:A:W277	3.71	No	Yes	0	5	6
111	A:A:H357	A:A:W277	15.87	No	Yes	0	7	6
112	A:A:C359	A:A:W277	5.22	Yes	Yes	10	5	6
113	A:A:N278	A:A:R280	3.62	No	No	0	8	5
114	A:A:L282	A:A:N279	10.98	Yes	No	0	9	8
115	A:A:R280	A:A:W281	3	No	No	0	5	5
116	A:A:H357	A:A:R283	5.64	No	No	0	7	3
117	A:A:I285	A:A:T284	3.04	No	No	0	7	4
118	A:A:R356	A:A:T284	14.23	Yes	No	0	2	4
119	A:A:H357	A:A:S286	2.79	No	No	0	7	8
120	A:A:I382	A:A:S286	6.19	No	No	0	6	8
121	A:A:C359	A:A:V287	3.42	Yes	No	10	5	6
122	A:A:D378	A:A:I288	9.8	Yes	No	0	7	9
123	A:A:F345	A:A:L289	4.87	Yes	No	0	8	9
124	A:A:F290	A:A:T364	9.08	No	Yes	15	9	9
125	A:A:F290	A:A:N371	4.83	No	No	15	9	9
126	A:A:F363	A:A:L291	7.31	Yes	No	0	5	8
127	A:A:K293	A:A:N292	16.79	No	Yes	0	9	9
128	A:A:N292	A:A:S366	5.96	Yes	Yes	0	9	9
129	A:A:K293	A:A:L296	8.46	No	Yes	20	9	6
130	A:A:F363	A:A:Q294	7.03	Yes	No	0	5	6
131	A:A:D295	A:A:L296	4.07	No	Yes	0	9	6
132	A:A:D295	A:A:S366	4.42	No	Yes	0	9	9
133	A:A:E299	A:A:L296	3.98	No	Yes	0	6	6
134	A:A:K300	A:A:S306	6.12	No	No	21	9	7
135	A:A:V301	A:A:V334	3.21	No	No	0	7	4
136	A:A:E309	A:A:K307	4.05	No	No	0	4	6
137	A:A:I308	A:A:Y311	2.42	No	No	0	7	6
138	A:A:F315	A:A:I308	5.02	Yes	No	0	6	7
139	A:A:E309	A:A:F315	3.5	No	Yes	0	4	6
140	A:A:E314	A:A:F340	13.99	No	Yes	12	6	7
141	A:A:E314	A:A:E344	8.88	No	No	12	6	5
142	A:A:F315	A:A:R333	10.69	Yes	No	0	6	5
143	A:A:F315	A:A:F340	7.5	Yes	Yes	0	6	7
144	A:A:R336	A:A:Y318	3.09	No	Yes	0	5	6
145	A:A:Y318	A:A:Y339	2.98	Yes	Yes	0	6	3
146	A:A:F340	A:A:Y318	11.35	Yes	Yes	12	7	6
147	A:A:D343	A:A:Y318	6.9	Yes	Yes	12	3	6
148	A:A:P321	A:A:T320	3.5	No	No	0	5	1
149	A:A:R336	A:A:T320	9.06	No	No	0	5	1
150	A:A:D323	A:A:P321	3.22	No	No	0	4	5
151	A:A:P321	A:A:Y339	12.52	No	Yes	0	5	3
152	A:A:A324	A:A:Y339	4	No	Yes	0	3	3
153	A:A:E330	A:A:P326	6.29	Yes	No	0	3	1
154	A:A:E327	A:A:E330	7.61	No	Yes	0	4	3
155	A:A:E327	A:A:K338	2.7	No	No	0	4	5
156	A:A:E330	A:A:V334	5.7	Yes	No	0	3	4
157	A:A:E330	A:A:T335	9.88	Yes	No	0	3	4
158	A:A:D331	A:A:P332	3.22	No	No	0	4	1
159	A:A:D331	A:A:R333	3.57	No	No	0	4	5
160	A:A:D331	A:A:V334	8.76	No	No	0	4	4
161	A:A:F363	A:A:K338	16.13	Yes	No	0	5	5
162	A:A:R342	A:A:Y339	10.29	No	Yes	0	4	3
163	A:A:D343	A:A:F340	2.39	Yes	Yes	12	3	7
164	A:A:E344	A:A:F340	8.16	No	Yes	12	5	7
165	A:A:F345	A:A:I341	2.51	Yes	No	0	8	8
166	A:A:P361	A:A:R342	4.32	No	No	0	5	4
167	A:A:F363	A:A:R342	13.9	Yes	No	0	5	4
168	A:A:D343	A:A:E344	12.99	Yes	No	12	3	5
169	A:A:D343	A:A:R347	3.57	Yes	No	0	3	4
170	A:A:L346	A:A:S349	3	No	No	10	4	7
171	A:A:C359	A:A:L346	3.17	Yes	No	10	5	4
172	A:A:L346	A:A:P361	3.28	No	No	0	4	5
173	A:A:C359	A:A:S349	5.16	Yes	No	10	5	7
174	A:A:G353	A:A:S352	3.71	No	No	0	4	5
175	A:A:D354	A:A:G353	3.35	No	No	0	3	4
176	A:A:R356	A:A:R385	4.26	Yes	Yes	11	2	5
177	A:A:M386	A:A:R356	8.69	No	Yes	11	3	2
178	A:A:R385	A:A:Y358	8.23	Yes	No	0	5	4
179	A:A:D378	A:A:Y360	22.99	Yes	No	22	7	8
180	A:A:D381	A:A:Y360	4.6	No	No	0	8	8
181	A:A:I382	A:A:Y360	2.42	No	No	22	6	8
182	A:A:H362	A:A:R374	18.05	No	No	0	9	4
183	A:A:D378	A:A:H362	5.04	Yes	No	0	7	9
184	A:A:D368	A:A:T364	5.78	Yes	Yes	15	9	9
185	A:A:N371	A:A:T364	4.39	No	Yes	15	9	9
186	A:A:R374	A:A:T364	6.47	No	Yes	0	4	9
187	A:A:C365	A:A:D368	3.11	No	Yes	0	8	9
188	A:A:D368	A:A:E370	7.8	Yes	No	0	9	4
189	A:A:D368	A:A:N371	13.46	Yes	No	15	9	9
190	A:A:E370	A:A:T369	2.82	No	No	0	4	9
191	A:A:F376	A:A:R373	4.28	Yes	No	0	8	5
192	A:A:N377	A:A:R373	10.85	No	No	0	4	5
193	A:A:F376	R:R:F665	11.79	Yes	Yes	7	8	8
194	A:A:D378	A:A:N377	2.69	Yes	No	0	7	4
195	A:A:D378	A:A:I382	2.8	Yes	No	22	7	6
196	A:A:R380	R:R:V664	3.92	No	Yes	0	7	9
197	A:A:R380	R:R:F665	4.28	No	Yes	0	7	8
198	A:A:H387	A:A:I383	6.63	Yes	No	23	8	8
199	A:A:I383	R:R:V664	4.61	No	Yes	23	8	9
200	A:A:Q384	R:R:V664	2.87	No	Yes	0	6	9
201	A:A:Q384	R:R:V737	2.87	No	No	0	6	8
202	A:A:M386	A:A:R385	3.72	No	Yes	11	3	5
203	A:A:R385	A:A:R389	10.66	Yes	No	11	5	4
204	A:A:L394	A:A:R385	7.29	Yes	Yes	11	8	5
205	A:A:M386	A:A:R389	2.48	No	No	11	3	4
206	A:A:H387	R:R:M660	7.88	Yes	No	0	8	8
207	A:A:H387	R:R:V664	2.77	Yes	Yes	23	8	9
208	A:A:H387	R:R:S667	4.18	Yes	No	0	8	8
209	A:A:L388	A:A:L394	2.77	No	Yes	0	8	8
210	A:A:L394	A:A:R389	12.15	Yes	No	11	8	4
211	A:A:Q390	R:R:R601	14.02	No	Yes	0	4	8
212	A:A:Y391	R:R:R601	8.23	No	Yes	0	4	8
213	A:A:Y391	R:R:L657	3.52	No	No	0	4	9
214	A:A:Y391	R:R:M660	3.59	No	No	0	4	8
215	A:A:E392	R:R:S811	2.87	No	No	0	6	8
216	A:A:L393	R:R:V764	2.98	No	No	0	8	8
217	A:A:L393	R:R:L765	6.92	No	No	0	8	9
218	A:A:L394	R:R:L757	5.54	Yes	No	0	8	8
219	B:B:D5	B:B:E3	10.39	No	No	0	1	5
220	B:B:E3	B:B:Q6	2.55	No	No	0	5	1
221	B:B:Q9	B:B:R8	8.18	No	No	0	3	3
222	B:B:E12	B:B:Q9	6.37	No	No	0	4	3
223	B:B:E10	B:B:Q13	12.74	No	No	0	8	1
224	B:B:E12	B:B:Q13	3.82	No	No	0	4	1
225	B:B:L14	B:B:Q13	3.99	No	No	0	8	1
226	B:B:L14	B:B:Q17	5.32	No	No	0	8	4
227	B:B:L14	G:G:L19	5.54	No	No	0	8	9
228	B:B:K15	G:G:L19	7.05	No	No	0	6	9
229	B:B:I18	B:B:R19	3.76	No	No	0	7	4
230	B:B:R19	B:B:R22	3.2	No	Yes	0	4	6
231	B:B:R19	B:B:T223	2.59	No	No	0	4	2
232	B:B:D20	B:B:K23	2.77	No	No	0	2	2
233	B:B:D258	B:B:R22	10.72	Yes	Yes	0	7	6
234	B:B:Q259	B:B:R22	5.84	Yes	Yes	0	6	6
235	B:B:R22	G:G:R27	9.6	Yes	No	0	6	8
236	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
237	B:B:C25	G:G:R27	13.93	No	No	0	3	8
238	B:B:A26	B:B:Q259	3.03	No	Yes	0	3	6
239	B:B:A28	B:B:D27	3.09	No	No	0	4	8
240	B:B:D27	G:G:K29	9.68	No	No	0	8	4
241	B:B:L261	B:B:T29	2.95	No	No	0	5	3
242	B:B:M262	B:B:S31	4.6	No	No	0	4	1
243	B:B:L300	B:B:T34	10.32	Yes	Yes	2	6	5
244	B:B:K301	B:B:T34	6.01	No	Yes	0	5	5
245	B:B:T34	G:G:M38	4.52	Yes	No	2	5	4
246	B:B:N35	B:B:N36	9.54	No	No	0	1	1
247	B:B:I37	B:B:R283	5.01	No	Yes	0	2	9
248	B:B:I37	G:G:E42	2.73	No	No	0	2	1
249	B:B:R283	B:B:V40	2.62	Yes	Yes	2	9	3
250	B:B:L284	B:B:V40	2.98	No	Yes	2	5	3
251	B:B:D298	B:B:V40	4.38	Yes	Yes	2	9	3
252	B:B:I43	B:B:M45	2.92	No	No	0	3	4
253	B:B:M45	B:B:N340	5.61	No	No	0	4	9
254	B:B:K337	B:B:T47	4.5	Yes	No	3	6	3
255	B:B:T47	B:B:W339	4.85	No	Yes	3	3	9
256	B:B:N340	B:B:R48	12.05	No	No	13	9	7
257	B:B:R48	G:G:N59	2.41	No	Yes	13	7	9
258	B:B:I338	B:B:R49	3.76	No	No	0	5	7
259	B:B:R52	B:B:T50	9.06	No	No	0	7	3
260	B:B:K337	B:B:T50	6.01	Yes	No	0	6	3
261	B:B:L51	B:B:W82	10.25	No	Yes	8	9	9
262	B:B:L51	B:B:T87	4.42	No	No	0	9	5
263	B:B:L336	B:B:L51	5.54	No	No	8	7	9
264	B:B:F335	B:B:R52	3.21	No	No	0	4	7
265	B:B:G53	B:B:W82	2.81	No	Yes	0	9	9
266	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
267	B:B:H54	B:B:S72	11.16	Yes	No	8	9	9
268	B:B:H54	B:B:S74	5.58	Yes	No	0	9	9
269	B:B:H54	B:B:I80	7.95	Yes	No	8	9	8
270	B:B:H54	B:B:W82	3.17	Yes	Yes	8	9	9
271	B:B:D76	B:B:L55	10.86	Yes	No	17	9	6
272	B:B:K57	B:B:Y59	2.39	Yes	Yes	1	9	8
273	B:B:K57	B:B:Q75	10.85	Yes	Yes	1	9	9
274	B:B:K57	B:B:W332	16.24	Yes	Yes	0	9	9
275	B:B:G330	B:B:I58	3.53	No	No	0	5	9
276	B:B:Q75	B:B:Y59	13.53	Yes	Yes	1	9	8
277	B:B:M101	B:B:Y59	5.99	No	Yes	0	9	8
278	B:B:A60	B:B:C103	3.61	No	No	0	7	8
279	B:B:M61	B:B:W63	4.65	No	No	0	6	7
280	B:B:C317	B:B:M61	6.48	No	No	0	7	6
281	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
282	B:B:H62	B:B:R150	5.64	No	No	0	6	6
283	B:B:T321	B:B:W63	7.28	Yes	No	0	7	7
284	B:B:A328	B:B:W63	3.89	No	No	0	5	7
285	B:B:D66	B:B:R68	5.96	No	No	0	8	5
286	B:B:S67	B:B:T321	7.99	No	Yes	24	5	7
287	B:B:D323	B:B:S67	8.83	No	No	24	7	5
288	B:B:L69	B:B:R68	3.64	No	No	0	5	5
289	B:B:D83	B:B:R68	15.48	No	No	0	8	5
290	B:B:I81	B:B:L69	2.85	Yes	No	0	7	5
291	B:B:V71	B:B:Y105	2.52	No	Yes	0	8	6
292	B:B:I80	B:B:S72	3.1	No	No	8	8	9
293	B:B:Q75	B:B:W99	4.38	Yes	Yes	1	9	9
294	B:B:D76	B:B:K78	11.06	Yes	No	0	9	8
295	B:B:I93	B:B:L79	4.28	Yes	No	0	7	7
296	B:B:I80	B:B:W82	12.92	No	Yes	8	8	9
297	B:B:I81	B:B:V90	3.07	Yes	No	25	7	5
298	B:B:H91	B:B:I81	5.3	No	Yes	25	5	7
299	B:B:I81	B:B:L126	5.71	Yes	No	0	7	5
300	B:B:K89	B:B:W82	12.76	Yes	Yes	0	9	9
301	B:B:L336	B:B:W82	4.56	No	Yes	8	7	9
302	B:B:D83	B:B:Y85	3.45	No	No	0	8	4
303	B:B:D83	B:B:T86	2.89	No	No	0	8	6
304	B:B:S84	B:B:Y85	2.54	No	No	0	5	4
305	B:B:S84	G:G:F61	3.96	No	Yes	0	5	8
306	B:B:Y85	G:G:P60	4.17	No	Yes	0	4	9
307	B:B:N88	B:B:T86	13.16	Yes	No	0	7	6
308	B:B:H91	B:B:V90	8.3	No	No	25	5	5
309	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
310	B:B:I93	B:B:Y124	7.25	Yes	No	0	7	6
311	B:B:I93	B:B:V133	4.61	Yes	No	0	7	4
312	B:B:D118	B:B:S97	8.83	No	No	0	9	8
313	B:B:S98	B:B:W99	9.88	No	Yes	1	8	9
314	B:B:L117	B:B:W99	3.42	No	Yes	0	9	9
315	B:B:M101	B:B:Y145	2.39	No	Yes	0	9	8
316	B:B:C149	B:B:T102	3.38	No	No	0	8	8
317	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
318	B:B:G109	B:B:Y105	4.35	No	Yes	0	5	6
319	B:B:V112	B:B:Y105	5.05	No	Yes	0	8	6
320	B:B:A106	B:B:F151	8.32	No	Yes	0	6	9
321	B:B:N110	B:B:S108	7.45	No	No	0	4	6
322	B:B:N110	B:B:Y111	3.49	No	No	0	4	4
323	B:B:N125	B:B:Y111	5.81	No	No	0	4	4
324	B:B:F151	B:B:Y111	3.09	Yes	No	0	9	4
325	B:B:L126	B:B:V112	4.47	No	No	0	5	8
326	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
327	B:B:C114	B:B:Y124	2.69	No	No	0	8	6
328	B:B:D118	B:B:I120	4.2	No	Yes	0	9	6
329	B:B:G144	B:B:N119	5.09	No	No	0	8	9
330	B:B:E138	B:B:I120	2.73	No	Yes	0	6	6
331	B:B:C121	B:B:L139	3.17	No	No	0	8	9
332	B:B:C121	B:B:L146	3.17	No	No	0	8	7
333	B:B:I123	B:B:S136	6.19	Yes	No	0	6	4
334	B:B:I123	B:B:R137	2.51	Yes	No	0	6	5
335	B:B:I123	B:B:I171	4.42	Yes	No	0	6	6
336	B:B:V135	B:B:Y124	6.31	No	No	0	4	6
337	B:B:E130	B:B:R129	3.49	No	No	0	3	3
338	B:B:N132	B:B:V133	4.43	No	No	0	3	4
339	B:B:L139	B:B:W169	15.94	No	Yes	0	9	8
340	B:B:H142	B:B:S161	16.74	Yes	No	0	9	9
341	B:B:D163	B:B:H142	5.04	No	Yes	0	9	9
342	B:B:H142	B:B:T165	2.74	Yes	No	0	9	7
343	B:B:A167	B:B:H142	4.39	No	Yes	0	4	9
344	B:B:H142	B:B:W169	4.23	Yes	Yes	0	9	8
345	B:B:D163	B:B:T143	11.56	No	No	0	9	5
346	B:B:D163	B:B:G144	3.35	No	No	0	9	8
347	B:B:G162	B:B:Y145	5.79	No	Yes	14	9	8
348	B:B:D186	B:B:Y145	13.79	No	Yes	14	9	8
349	B:B:L146	B:B:T159	2.95	No	No	0	7	9
350	B:B:L146	B:B:S161	3	No	No	0	7	9
351	B:B:M188	B:B:S147	3.07	No	No	0	8	9
352	B:B:C148	B:B:L190	4.76	No	Yes	0	6	5
353	B:B:C149	B:B:I157	3.27	No	No	0	8	7
354	B:B:C149	B:B:T159	3.38	No	No	0	8	9
355	B:B:F151	B:B:I157	3.77	Yes	No	0	9	7
356	B:B:D153	B:B:L152	8.14	No	No	0	5	3
357	B:B:L152	B:B:L192	4.15	No	No	0	3	5
358	B:B:L152	B:B:T196	5.9	No	No	0	3	1
359	B:B:N155	B:B:Q156	6.6	No	No	0	3	5
360	B:B:D170	B:B:Q156	5.22	No	No	0	9	5
361	B:B:L168	B:B:V158	2.98	Yes	No	0	6	5
362	B:B:F199	B:B:V158	2.62	Yes	No	0	9	5
363	B:B:T159	B:B:W169	3.64	No	Yes	0	9	8
364	B:B:C166	B:B:S160	3.44	No	No	0	8	6
365	B:B:S160	B:B:V187	4.85	No	No	0	6	9
366	B:B:L190	B:B:S160	3	Yes	No	0	5	6
367	B:B:D186	B:B:G162	5.03	No	No	14	9	9
368	B:B:T165	B:B:T181	3.14	No	No	0	7	2
369	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
370	B:B:C166	B:B:S201	3.44	No	No	0	8	9
371	B:B:A167	B:B:Q176	4.55	No	No	0	4	4
372	B:B:L168	B:B:T177	4.42	Yes	Yes	6	6	4
373	B:B:L168	B:B:T178	2.95	Yes	No	6	6	4
374	B:B:F180	B:B:L168	3.65	Yes	Yes	6	7	6
375	B:B:Q176	B:B:W169	5.48	No	Yes	0	4	8
376	B:B:D170	B:B:T177	5.78	No	Yes	0	9	4
377	B:B:Q175	B:B:T177	2.83	No	Yes	0	4	4
378	B:B:Q176	B:B:T179	5.67	No	No	0	4	4
379	B:B:T177	B:B:T178	4.71	Yes	No	6	4	4
380	B:B:T179	B:B:T181	4.71	No	No	0	4	2
381	B:B:F180	B:B:F199	7.5	Yes	Yes	6	7	9
382	B:B:F180	B:B:W211	19.04	Yes	Yes	6	7	8
383	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
384	B:B:G182	B:B:T181	3.64	No	No	0	6	2
385	B:B:H183	B:B:V187	5.54	No	No	0	9	9
386	B:B:A203	B:B:H183	4.39	No	No	0	8	9
387	B:B:H183	B:B:K209	17.03	No	No	0	9	6
388	B:B:G185	B:B:T184	3.64	No	No	0	5	3
389	B:B:D205	B:B:T184	7.23	No	No	0	9	3
390	B:B:I229	B:B:S189	4.64	No	No	0	7	7
391	B:B:I232	B:B:S189	6.19	No	No	0	8	7
392	B:B:F199	B:B:L190	3.65	Yes	Yes	0	9	5
393	B:B:L190	B:B:S201	3	Yes	No	0	5	9
394	B:B:F234	B:B:S191	3.96	Yes	No	0	5	8
395	B:B:F199	B:B:L192	2.44	Yes	No	0	9	5
396	B:B:A193	B:B:F234	6.93	No	Yes	0	4	5
397	B:B:D195	B:B:P194	3.22	No	No	0	5	4
398	B:B:L198	B:B:R197	2.43	No	No	0	3	5
399	B:B:D212	B:B:R197	2.38	Yes	No	0	9	5
400	B:B:L198	B:B:L210	4.15	No	Yes	0	3	5
401	B:B:F199	B:B:W211	7.02	Yes	Yes	6	9	8
402	B:B:F199	B:B:V213	3.93	Yes	No	0	9	4
403	B:B:L210	B:B:V200	2.98	Yes	No	0	5	6
404	B:B:F234	B:B:V200	2.62	Yes	No	0	5	6
405	B:B:S201	B:B:W211	2.47	No	Yes	0	9	8
406	B:B:G202	B:B:I229	5.29	No	No	0	6	7
407	B:B:A203	B:B:D205	3.09	No	No	0	8	9
408	B:B:C204	B:B:D228	3.11	No	No	0	7	9
409	B:B:D205	B:B:S207	4.42	No	No	0	9	5
410	B:B:A208	B:B:F222	5.55	No	Yes	0	6	8
411	B:B:K209	B:B:W211	20.89	No	Yes	6	6	8
412	B:B:C218	B:B:K209	12.93	No	No	6	5	6
413	B:B:L210	B:B:R219	4.86	Yes	Yes	0	5	5
414	B:B:L210	B:B:Q220	6.65	Yes	Yes	0	5	7
415	B:B:L210	B:B:L255	4.15	Yes	No	0	5	6
416	B:B:C218	B:B:W211	7.84	No	Yes	6	5	8
417	B:B:D212	B:B:R214	2.38	Yes	No	16	9	9
418	B:B:D212	B:B:E215	15.59	Yes	No	16	9	3
419	B:B:D212	B:B:R219	11.91	Yes	Yes	16	9	5
420	B:B:R214	B:B:V213	5.23	No	No	0	9	4
421	B:B:E215	B:B:R214	4.65	No	No	16	3	9
422	B:B:E215	B:B:R219	3.49	No	Yes	16	3	5
423	B:B:M217	B:B:R219	6.2	No	Yes	0	3	5
424	B:B:M217	G:G:M21	7.22	No	No	0	3	1
425	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
426	B:B:D258	B:B:Q220	7.83	Yes	Yes	0	7	7
427	B:B:Q220	G:G:E22	7.65	Yes	No	0	7	9
428	B:B:Q220	G:G:I25	13.72	Yes	No	0	7	2
429	B:B:F222	B:B:F241	7.5	Yes	Yes	4	8	6
430	B:B:F222	B:B:F253	20.36	Yes	Yes	4	8	6
431	B:B:D258	B:B:F222	11.94	Yes	Yes	4	7	8
432	B:B:G224	B:B:T223	3.64	No	No	0	6	2
433	B:B:E260	B:B:T223	4.23	No	No	0	6	2
434	B:B:H225	B:B:I229	2.65	Yes	No	0	9	7
435	B:B:H225	B:B:T243	6.85	Yes	No	4	9	8
436	B:B:H225	B:B:S245	13.95	Yes	No	0	9	9
437	B:B:H225	B:B:T249	2.74	Yes	No	4	9	6
438	B:B:H225	B:B:R251	14.67	Yes	No	4	9	8
439	B:B:D247	B:B:E226	3.9	No	No	0	9	3
440	B:B:D228	B:B:S227	4.42	No	Yes	26	9	6
441	B:B:S227	B:B:S245	4.89	Yes	No	0	6	9
442	B:B:D246	B:B:S227	4.42	No	Yes	26	9	6
443	B:B:D247	B:B:S227	2.94	No	Yes	0	9	6
444	B:B:D228	B:B:D246	9.31	No	No	26	9	9
445	B:B:D246	B:B:N230	10.77	No	No	0	9	9
446	B:B:F241	B:B:I232	5.02	Yes	No	4	6	8
447	B:B:I232	B:B:T243	4.56	No	No	4	8	8
448	B:B:F234	B:B:G238	4.52	Yes	No	0	5	7
449	B:B:F235	B:B:P236	8.67	Yes	No	0	6	7
450	B:B:F235	B:B:N237	3.62	Yes	No	0	6	5
451	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
452	B:B:F235	B:B:F278	9.65	Yes	No	0	6	7
453	B:B:F235	B:B:G282	3.01	Yes	No	0	6	9
454	B:B:F235	G:G:L37	2.44	Yes	No	0	6	7
455	B:B:F235	G:G:Y40	3.09	Yes	No	0	6	6
456	B:B:N237	B:B:N239	6.81	No	No	0	5	2
457	B:B:N237	G:G:D36	5.39	No	No	0	5	5
458	B:B:F241	B:B:T243	2.59	Yes	No	4	6	8
459	B:B:F241	B:B:F253	17.15	Yes	Yes	4	6	6
460	B:B:D247	B:B:T249	4.34	No	No	0	9	6
461	B:B:R251	B:B:T249	7.76	No	No	4	8	6
462	B:B:C250	B:B:Y264	4.03	Yes	Yes	0	8	5
463	B:B:C250	B:B:I273	6.55	Yes	No	0	8	6
464	B:B:E260	B:B:R251	10.47	No	No	0	6	8
465	B:B:D254	B:B:F253	3.58	Yes	Yes	0	9	6
466	B:B:D258	B:B:F253	8.36	Yes	Yes	4	7	6
467	B:B:E260	B:B:F253	11.66	No	Yes	0	6	6
468	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
469	B:B:D254	B:B:L261	6.79	Yes	No	0	9	5
470	B:B:R256	G:G:I28	3.76	No	No	0	9	4
471	B:B:R256	G:G:K32	7.43	No	No	0	9	5
472	B:B:R256	G:G:A33	2.77	No	No	0	9	7
473	B:B:A257	B:B:Q259	4.55	No	Yes	0	7	6
474	B:B:A257	G:G:R27	2.77	No	No	0	7	8
475	B:B:L261	G:G:V30	2.98	No	No	0	5	8
476	B:B:M262	B:B:Y264	13.17	No	Yes	0	4	5
477	B:B:L285	B:B:Y264	5.86	No	Yes	0	6	5
478	B:B:W297	B:B:Y264	2.89	No	Yes	0	8	5
479	B:B:H266	B:B:I269	2.65	No	No	0	4	4
480	B:B:H266	B:B:R304	9.03	No	No	0	4	5
481	B:B:I269	B:B:Y289	9.67	No	Yes	0	4	7
482	B:B:C271	B:B:D291	7.78	No	No	0	5	8
483	B:B:I273	B:B:Y289	8.46	No	Yes	0	6	7
484	B:B:R314	B:B:T274	2.59	No	No	0	8	8
485	B:B:L318	B:B:S277	3	No	No	0	6	5
486	B:B:G319	B:B:S277	3.71	No	No	0	5	5
487	B:B:S277	B:B:V320	4.85	No	No	0	5	7
488	B:B:F278	B:B:L285	9.74	No	No	0	7	6
489	B:B:S279	B:B:S281	3.26	No	Yes	2	9	9
490	B:B:S279	G:G:D48	4.42	No	Yes	2	9	9
491	B:B:G324	B:B:K280	3.49	No	No	0	9	1
492	B:B:K280	G:G:H44	2.62	No	No	0	1	6
493	B:B:G282	B:B:S281	3.71	No	Yes	0	9	9
494	B:B:S281	G:G:D48	10.31	Yes	Yes	2	9	9
495	B:B:S281	G:G:L51	3	Yes	Yes	2	9	6
496	B:B:L284	B:B:R283	2.43	No	Yes	2	5	9
497	B:B:D298	B:B:R283	7.15	Yes	Yes	2	9	9
498	B:B:L300	B:B:R283	12.15	Yes	Yes	2	6	9
499	B:B:R283	G:G:C41	2.79	Yes	No	2	9	7
500	B:B:R283	G:G:L51	2.43	Yes	Yes	2	9	6
501	B:B:A299	B:B:L285	3.15	No	No	0	5	6
502	B:B:L286	B:B:V296	2.98	No	No	0	7	5
503	B:B:L286	B:B:L318	2.77	No	No	0	7	6
504	B:B:L286	B:B:V327	5.96	No	No	0	7	6
505	B:B:A287	B:B:Y289	2.67	No	Yes	0	6	7
506	B:B:N295	B:B:Y289	5.81	Yes	Yes	0	6	7
507	B:B:W297	B:B:Y289	3.86	No	Yes	0	8	7
508	B:B:D290	B:B:R314	15.48	No	No	0	6	8
509	B:B:F292	B:B:N313	2.42	No	Yes	0	4	7
510	B:B:N293	B:B:N295	2.72	No	Yes	0	5	6
511	B:B:C294	B:B:L308	3.17	No	No	0	5	7
512	B:B:N295	B:B:R304	9.64	Yes	No	27	6	5
513	B:B:N295	B:B:V307	4.43	Yes	No	27	6	3
514	B:B:D298	B:B:L300	4.07	Yes	Yes	2	9	6
515	B:B:D298	B:B:K301	13.83	Yes	No	0	9	5
516	B:B:L300	G:G:M38	4.24	Yes	No	2	6	4
517	B:B:L300	G:G:C41	3.17	Yes	No	2	6	7
518	B:B:R304	B:B:V307	3.92	No	No	27	5	3
519	B:B:V307	R:R:L826	7.45	No	No	0	3	8
520	B:B:L308	B:B:W339	18.22	No	Yes	0	7	9
521	B:B:H311	B:B:V315	4.15	Yes	Yes	3	9	7
522	B:B:H311	B:B:T329	6.85	Yes	Yes	3	9	8
523	B:B:H311	B:B:S331	11.16	Yes	Yes	3	9	9
524	B:B:D333	B:B:H311	6.3	Yes	Yes	3	9	9
525	B:B:H311	B:B:K337	6.55	Yes	Yes	3	9	6
526	B:B:D312	B:B:N313	2.69	No	Yes	3	5	7
527	B:B:D312	B:B:D333	9.31	No	Yes	3	5	9
528	B:B:D312	R:R:S595	8.83	No	No	0	5	9
529	B:B:N313	B:B:S331	2.98	Yes	Yes	3	7	9
530	B:B:N313	B:B:W332	5.65	Yes	Yes	0	7	9
531	B:B:D333	B:B:N313	6.73	Yes	Yes	3	9	7
532	B:B:R314	B:B:W332	14.99	No	Yes	0	8	9
533	B:B:T329	B:B:V315	3.17	Yes	Yes	3	8	7
534	B:B:S331	B:B:V315	3.23	Yes	Yes	3	9	7
535	B:B:S316	B:B:W332	7.41	No	Yes	0	9	9
536	B:B:L318	B:B:T329	2.95	No	Yes	0	6	8
537	B:B:V320	B:B:V327	3.21	No	No	0	7	6
538	B:B:D323	B:B:T321	10.12	No	Yes	24	7	7
539	B:B:D323	B:B:M325	11.09	No	No	0	7	5
540	B:B:M325	G:G:P49	3.35	No	No	0	5	7
541	B:B:M325	G:G:P60	3.35	No	Yes	0	5	9
542	B:B:A326	G:G:F61	2.77	No	Yes	0	7	8
543	B:B:V327	B:B:W339	3.68	No	Yes	0	6	9
544	B:B:G330	B:B:T329	3.64	No	Yes	0	5	8
545	B:B:T329	B:B:W339	6.06	Yes	Yes	3	8	9
546	B:B:D333	B:B:S331	10.31	Yes	Yes	3	9	9
547	B:B:D333	B:B:F335	9.55	Yes	No	0	9	4
548	B:B:F335	B:B:S334	2.64	No	No	0	4	4
549	B:B:K337	B:B:W339	4.64	Yes	Yes	3	6	9
550	B:B:I338	G:G:F61	2.51	No	Yes	0	5	8
551	B:B:N340	G:G:N59	10.9	No	Yes	13	9	9
552	G:G:A7	G:G:N5	4.69	No	No	0	4	4
553	G:G:N5	G:G:S8	2.98	No	No	0	4	4
554	G:G:I9	G:G:S8	3.1	No	No	0	2	4
555	G:G:K14	G:G:R13	3.71	No	No	0	4	6
556	G:G:E17	G:G:K14	2.7	No	No	0	6	4
557	G:G:K20	G:G:V16	6.07	No	No	0	6	7
558	G:G:E17	G:G:Q18	7.65	No	No	0	6	9
559	G:G:K29	G:G:V30	3.04	No	No	0	4	8
560	G:G:K29	G:G:S31	4.59	No	No	0	4	9
561	G:G:E47	G:G:H44	18.46	No	No	0	3	6
562	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
563	G:G:D48	G:G:L50	4.07	Yes	No	0	9	9
564	G:G:D48	G:G:L51	10.86	Yes	Yes	2	9	6
565	G:G:P49	G:G:V54	3.53	No	No	0	7	6
566	G:G:L51	G:G:T52	4.42	Yes	No	0	6	4
567	G:G:P53	G:G:T52	3.5	No	No	0	8	4
568	G:G:P55	G:G:V54	5.3	No	No	0	5	6
569	G:G:A56	G:G:R62	4.15	No	No	0	4	7
570	G:G:E58	G:G:S57	8.62	No	No	0	5	6
571	G:G:N59	G:G:P60	6.52	Yes	Yes	13	9	9
572	G:G:F61	G:G:N59	3.62	Yes	Yes	13	8	9
573	G:G:F61	G:G:P60	5.78	Yes	Yes	13	8	9
574	L:L:?1	R:R:Q563	3.22	Yes	No	0	0	4
575	L:L:?1	R:R:W705	10.09	Yes	Yes	0	0	9
576	L:L:?1	R:R:N795	3.32	Yes	No	0	0	9
577	R:R:V553	R:R:V780	3.21	No	No	0	8	7
578	R:R:P555	R:R:V554	3.53	No	No	0	6	8
579	R:R:L708	R:R:P555	3.28	No	No	0	7	6
580	R:R:H562	R:R:L558	20.57	Yes	No	28	7	5
581	R:R:L558	R:R:Q563	9.32	No	No	0	5	4
582	R:R:L558	R:R:L566	5.54	No	No	28	5	9
583	R:R:H562	R:R:L566	16.71	Yes	No	28	7	9
584	R:R:H562	R:R:Q788	25.96	Yes	No	0	7	8
585	R:R:H562	R:R:Y789	11.98	Yes	No	0	7	9
586	R:R:F623	R:R:S567	2.64	No	No	0	6	7
587	R:R:F623	R:R:Y571	12.38	No	No	29	6	7
588	R:R:R624	R:R:Y571	4.12	No	No	29	4	7
589	R:R:G573	R:R:L797	3.42	No	Yes	0	9	7
590	R:R:C574	R:R:Q616	4.58	No	No	0	8	8
591	R:R:C574	R:R:L620	4.76	No	No	0	8	8
592	R:R:Q616	R:R:S577	11.55	No	No	0	8	9
593	R:R:C580	R:R:F803	9.78	No	No	0	7	9
594	R:R:L581	R:R:S609	4.5	No	No	0	9	8
595	R:R:L581	R:R:V612	2.98	No	No	0	9	8
596	R:R:L581	R:R:L613	4.15	No	No	0	9	8
597	R:R:F588	R:R:T584	2.59	No	No	5	7	9
598	R:R:F803	R:R:T584	6.49	No	No	5	9	9
599	R:R:C807	R:R:T584	6.76	No	No	5	8	9
600	R:R:F610	R:R:L585	2.44	No	No	0	4	7
601	R:R:F588	R:R:Y602	6.19	No	Yes	5	7	8
602	R:R:C807	R:R:F588	4.19	No	No	5	8	7
603	R:R:K820	R:R:L591	5.64	No	No	0	8	8
604	R:R:K820	R:R:S593	4.59	No	No	0	8	8
605	R:R:A816	R:R:V594	5.09	No	No	0	8	8
606	R:R:K820	R:R:V594	3.04	No	No	0	8	8
607	R:R:I597	R:R:T596	3.04	No	No	0	8	9
608	R:R:E812	R:R:T596	2.82	Yes	No	0	8	9
609	R:R:I597	R:R:Y602	12.09	No	Yes	0	8	8
610	R:R:N599	R:R:R601	14.46	No	Yes	5	8	8
611	R:R:N599	R:R:Y602	8.14	No	Yes	5	8	8
612	R:R:H672	R:R:Q600	4.95	No	No	0	7	8
613	R:R:R601	R:R:Y602	5.14	Yes	Yes	5	8	8
614	R:R:H656	R:R:R601	5.64	No	Yes	0	8	8
615	R:R:E812	R:R:R601	5.82	Yes	Yes	5	8	8
616	R:R:N810	R:R:Y602	3.49	No	Yes	5	9	8
617	R:R:E812	R:R:Y602	8.98	Yes	Yes	5	8	8
618	R:R:V813	R:R:Y602	3.79	No	Yes	0	9	8
619	R:R:H603	R:R:H672	5.97	No	No	0	8	7
620	R:R:H603	R:R:Y676	3.27	No	Yes	0	8	8
621	R:R:I604	R:R:W649	5.87	No	Yes	0	9	9
622	R:R:E653	R:R:I604	2.73	Yes	No	0	9	9
623	R:R:I604	R:R:Y675	6.04	No	Yes	0	9	8
624	R:R:E653	R:R:H605	2.46	Yes	No	9	9	9
625	R:R:H605	R:R:I768	5.3	No	Yes	9	9	8
626	R:R:H605	R:R:H806	2.39	No	No	9	9	9
627	R:R:N607	R:R:W649	14.69	No	Yes	30	9	9
628	R:R:N607	R:R:Y676	4.65	No	Yes	30	9	8
629	R:R:L608	R:R:V612	2.98	No	No	0	9	8
630	R:R:L608	R:R:M650	4.24	No	No	0	9	9
631	R:R:Q616	R:R:V612	2.87	No	No	0	8	8
632	R:R:F642	R:R:V614	9.18	Yes	No	0	8	6
633	R:R:A615	R:R:F643	4.16	No	No	0	9	8
634	R:R:I621	R:R:V617	3.07	No	No	0	4	5
635	R:R:L618	R:R:M635	4.24	No	No	0	7	6
636	R:R:L618	R:R:L639	4.15	No	No	0	7	9
637	R:R:F642	R:R:L618	2.44	Yes	No	0	8	7
638	R:R:L619	R:R:W705	3.42	No	Yes	0	9	9
639	R:R:M635	R:R:S622	7.67	No	No	0	6	8
640	R:R:S622	R:R:W705	3.71	No	Yes	0	8	9
641	R:R:F623	R:R:R624	3.21	No	No	29	6	4
642	R:R:E626	R:R:L625	3.98	No	No	0	2	4
643	R:R:L625	R:R:M635	2.83	No	No	0	4	6
644	R:R:P631	R:R:T629	6.99	No	No	0	6	8
645	R:R:P631	R:R:T630	3.5	No	No	0	6	3
646	R:R:Q633	R:R:T630	2.83	No	No	0	5	3
647	R:R:C632	R:R:C704	7.28	No	No	31	9	9
648	R:R:H640	R:R:V637	6.92	No	No	32	9	4
649	R:R:V637	R:R:Y698	3.79	No	Yes	32	4	9
650	R:R:F642	R:R:L638	3.65	Yes	No	0	8	7
651	R:R:C687	R:R:H640	5.9	No	No	0	8	9
652	R:R:H640	R:R:Y698	14.16	No	Yes	32	9	9
653	R:R:W680	R:R:Y641	2.89	No	Yes	0	8	7
654	R:R:P683	R:R:Y641	4.17	Yes	Yes	0	8	7
655	R:R:C687	R:R:Y641	4.03	No	Yes	0	8	7
656	R:R:F643	R:R:F716	3.22	No	No	0	8	9
657	R:R:I686	R:R:L644	2.85	No	No	0	7	9
658	R:R:L644	R:R:P719	3.28	No	No	0	9	9
659	R:R:S645	R:R:W680	7.41	No	No	0	8	8
660	R:R:P683	R:R:S645	3.56	Yes	No	0	8	8
661	R:R:F647	R:R:M650	4.98	Yes	No	0	9	9
662	R:R:F647	R:R:F716	3.22	Yes	No	0	9	9
663	R:R:A720	R:R:F647	2.77	No	Yes	0	9	9
664	R:R:F647	R:R:W773	14.03	Yes	Yes	0	9	9
665	R:R:W649	R:R:Y676	2.89	Yes	Yes	30	9	8
666	R:R:G679	R:R:W649	8.44	No	Yes	0	9	9
667	R:R:W649	R:R:W680	14.99	Yes	No	0	9	8
668	R:R:G770	R:R:M650	3.49	No	No	0	9	9
669	R:R:L651	R:R:V723	4.47	No	No	0	9	8
670	R:R:L651	R:R:V726	2.98	No	No	0	9	8
671	R:R:V652	R:R:Y675	6.31	No	Yes	0	8	8
672	R:R:M678	R:R:V652	3.04	No	No	0	7	8
673	R:R:E653	R:R:G654	3.27	Yes	No	9	9	9
674	R:R:E653	R:R:I768	10.93	Yes	Yes	9	9	8
675	R:R:E653	R:R:L769	9.28	Yes	No	9	9	9
676	R:R:G654	R:R:L769	3.42	No	No	9	9	9
677	R:R:H656	R:R:M660	3.94	No	No	0	8	8
678	R:R:H656	R:R:Y675	11.98	No	Yes	0	8	8
679	R:R:L657	R:R:V661	2.98	No	No	0	9	9
680	R:R:L657	R:R:L765	4.15	No	No	0	9	9
681	R:R:I662	R:R:Y658	9.67	No	No	0	8	8
682	R:R:K663	R:R:Y658	3.58	No	No	0	7	8
683	R:R:I730	R:R:Y658	4.84	No	No	0	8	8
684	R:R:I662	R:R:V661	3.07	No	No	0	8	9
685	R:R:D669	R:R:K671	4.15	No	No	0	6	8
686	R:R:K671	R:R:Y675	2.39	No	Yes	0	8	8
687	R:R:F682	R:R:M678	3.73	No	No	0	4	7
688	R:R:I686	R:R:I689	2.94	No	No	0	7	6
689	R:R:S690	R:R:Y698	3.82	No	Yes	0	8	9
690	R:R:D696	R:R:S697	5.89	No	No	0	3	7
691	R:R:S697	R:R:S710	6.52	No	No	0	7	4
692	R:R:A712	R:R:S697	3.42	No	No	0	7	7
693	R:R:S707	R:R:T700	3.2	No	No	0	8	4
694	R:R:N702	R:R:N703	8.17	No	No	0	3	7
695	R:R:N703	R:R:W705	20.34	No	Yes	0	7	9
696	R:R:S707	R:R:S710	6.52	No	No	0	8	4
697	R:R:I713	R:R:L708	2.85	No	No	0	8	7
698	R:R:G711	R:R:S710	3.71	No	No	0	7	4
699	R:R:I713	R:R:V717	3.07	No	No	0	8	8
700	R:R:L721	R:R:V717	2.98	No	No	0	7	8
701	R:R:F722	R:R:V726	2.62	No	No	0	5	8
702	R:R:I724	R:R:V774	4.61	No	No	0	9	5
703	R:R:L769	R:R:N727	12.36	No	No	0	9	9
704	R:R:G729	R:R:I728	3.53	No	No	0	5	5
705	R:R:L731	R:R:T735	2.95	No	No	0	8	9
706	R:R:L731	R:R:L765	2.77	No	No	0	8	9
707	R:R:L757	R:R:S742	3	No	No	0	8	8
708	R:R:A754	R:R:F755	2.77	No	No	0	8	6
709	R:R:K756	R:R:K760	4.31	No	No	0	6	9
710	R:R:H806	R:R:V764	4.15	No	No	0	9	8
711	R:R:L766	R:R:P767	9.85	No	Yes	0	8	9
712	R:R:L766	R:R:T771	4.42	No	No	0	8	8
713	R:R:F801	R:R:P767	7.22	No	Yes	0	8	9
714	R:R:F805	R:R:P767	2.89	No	Yes	0	8	9
715	R:R:I768	R:R:I802	2.94	Yes	No	0	8	8
716	R:R:H806	R:R:I768	13.26	No	Yes	9	9	8
717	R:R:F775	R:R:S772	2.64	No	No	0	8	9
718	R:R:F791	R:R:W773	4.01	No	Yes	0	9	9
719	R:R:N795	R:R:W773	15.82	No	Yes	0	9	9
720	R:R:F775	R:R:F787	4.29	No	No	0	8	7
721	R:R:F791	R:R:G776	3.01	No	No	0	9	9
722	R:R:A784	R:R:Q788	3.03	No	No	0	6	8
723	R:R:V785	R:R:V786	4.81	No	No	0	5	5
724	R:R:L794	R:R:M790	2.83	Yes	No	0	6	5
725	R:R:F801	R:R:L794	2.44	No	Yes	0	8	6
726	R:R:N795	R:R:Q798	3.96	No	No	0	9	9
727	R:R:L797	R:R:S796	6.01	Yes	No	0	7	9
728	R:R:L797	R:R:L800	4.15	Yes	No	0	7	6
729	R:R:F801	R:R:L797	2.44	No	Yes	0	8	7
730	R:R:C807	R:R:F803	4.19	No	No	5	8	9
731	R:R:N810	R:R:S811	2.98	No	No	0	9	8
732	R:R:E812	R:R:N810	2.63	Yes	No	5	8	9
733	R:R:F817	R:R:T821	7.78	No	No	0	7	8
734	R:R:H819	R:R:V823	6.92	No	No	0	8	7
735	R:R:I724	R:R:W773	2.35	No	Yes	0	9	9
736	A:A:L297	A:A:Y263	2.34	No	Yes	0	8	6
737	R:R:L620	R:R:Y571	2.34	No	No	0	8	7
738	A:A:E314	A:A:F312	2.33	No	No	0	6	8
739	B:B:L70	B:B:W82	2.28	No	Yes	0	5	9
740	A:A:R22	B:B:H91	2.26	No	No	0	5	5
741	A:A:H220	A:A:R42	2.26	Yes	No	0	7	9
742	A:A:R283	A:A:R356	2.13	No	Yes	0	3	2
743	B:B:G115	B:B:G116	2.11	No	No	0	9	9
744	B:B:G144	B:B:G162	2.11	No	No	0	8	9
745	R:R:F642	R:R:Y641	2.06	Yes	Yes	0	8	7
746	B:B:G238	B:B:P194	2.03	No	No	0	7	4
747	R:R:G628	R:R:P627	2.03	Yes	No	0	7	5
748	R:R:G681	R:R:P683	2.03	No	Yes	0	9	8
749	B:B:C114	B:B:G115	1.96	No	No	0	8	9
750	B:B:C250	B:B:G244	1.96	Yes	No	0	8	5
751	R:R:C632	R:R:G628	1.96	No	Yes	31	9	7
752	R:R:C704	R:R:G628	1.96	No	Yes	31	9	7
753	B:B:A140	B:B:G141	1.95	No	No	0	5	5
754	B:B:A206	B:B:G224	1.95	No	No	0	4	6
755	B:B:A309	B:B:G310	1.95	No	No	0	3	5
756	R:R:A779	R:R:G776	1.95	No	No	0	8	9
757	B:B:A106	B:B:P107	1.87	No	No	0	6	6
758	R:R:A718	R:R:P719	1.87	No	No	0	7	9
759	A:A:G206	A:A:S205	1.86	No	No	0	8	7
760	R:R:G799	R:R:S577	1.86	No	No	0	8	9
761	A:A:G225	A:A:V224	1.84	No	Yes	0	9	9
762	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
763	B:B:G288	B:B:V315	1.84	No	Yes	0	7	7
764	B:B:G306	B:B:V296	1.84	No	No	0	4	5
765	B:B:G324	B:B:V320	1.84	No	No	0	9	7
766	R:R:G573	R:R:V572	1.84	No	No	0	9	5
767	B:B:G115	B:B:T102	1.82	No	No	0	9	8
768	B:B:G185	B:B:T164	1.82	No	No	0	5	6
769	R:R:G628	R:R:T629	1.82	Yes	No	0	7	8
770	R:R:G699	R:R:T700	1.82	No	No	0	8	4
771	B:B:A73	B:B:C103	1.81	No	No	0	9	8
772	R:R:A611	R:R:A646	1.79	No	No	0	8	7
773	R:R:A694	R:R:A712	1.79	No	No	0	6	7
774	A:A:P326	A:A:T325	1.75	No	No	0	1	2
775	B:B:P107	B:B:T65	1.75	No	No	0	6	1
776	A:A:G47	A:A:K53	1.74	No	Yes	0	9	9
777	B:B:G77	B:B:K78	1.74	No	No	0	8	8
778	A:A:C365	A:A:S366	1.72	No	Yes	0	8	9
779	B:B:C114	B:B:S122	1.72	No	No	0	8	8
780	A:A:G47	A:A:L46	1.71	No	No	0	9	8
781	B:B:C103	B:B:V71	1.71	No	No	0	8	8
782	B:B:G77	B:B:L95	1.71	No	No	0	8	8
783	B:B:G174	B:B:L139	1.71	No	No	0	4	9
784	B:B:C233	B:B:V276	1.71	No	No	0	3	6
785	B:B:C250	B:B:V276	1.71	Yes	No	0	8	6
786	R:R:A611	R:R:S645	1.71	No	No	0	8	8
787	R:R:G681	R:R:L684	1.71	No	No	0	9	5
788	B:B:A73	B:B:V100	1.7	No	No	0	9	9
789	B:B:A242	B:B:V276	1.7	No	No	0	4	6
790	B:B:A305	B:B:V296	1.7	No	No	0	4	5
791	R:R:A565	R:R:V564	1.7	No	No	0	6	5
792	R:R:I768	R:R:P767	1.69	Yes	Yes	0	8	9
793	B:B:D118	B:B:G116	1.68	No	No	0	9	9
794	B:B:D290	B:B:G272	1.68	No	No	0	6	4
795	R:R:A816	R:R:T596	1.68	No	No	0	8	9
796	B:B:K301	B:B:P39	1.67	No	No	0	5	1
797	B:B:C271	B:B:I270	1.64	No	No	0	5	3
798	R:R:L644	R:R:P683	1.64	No	Yes	0	9	8
799	R:R:S567	R:R:S568	1.63	No	No	0	7	5
800	A:A:S366	A:A:V367	1.62	Yes	No	0	9	9
801	B:B:I33	G:G:A34	1.62	No	No	0	3	6
802	B:B:A113	B:B:I123	1.62	No	Yes	0	9	6
803	B:B:A140	B:B:I120	1.62	No	Yes	0	5	6
804	R:R:S577	R:R:V578	1.62	No	No	0	9	7
805	R:R:A715	R:R:I686	1.62	No	No	0	9	7
806	R:R:A761	R:R:I738	1.62	No	No	0	9	9
807	B:B:D38	B:B:P39	1.61	No	No	0	1	1
808	G:G:A45	G:G:K46	1.61	No	No	0	4	1
809	A:A:S54	A:A:T55	1.6	No	No	0	9	9
810	A:A:S366	A:A:T55	1.6	Yes	No	0	9	9
811	B:B:S275	B:B:T274	1.6	No	No	0	8	8
812	R:R:V578	R:R:V617	1.6	No	No	0	7	5
813	R:R:V586	R:R:V590	1.6	No	No	0	6	4
814	R:R:G561	R:R:H562	1.59	No	Yes	0	2	7
815	R:R:T630	R:R:V634	1.59	No	No	0	3	4
816	A:A:A303	A:A:L302	1.58	No	No	0	5	2
817	B:B:L7	G:G:A12	1.58	No	No	0	8	5
818	B:B:L30	G:G:A34	1.58	No	No	0	5	6
819	B:B:A309	R:R:L826	1.58	No	No	0	3	8
820	R:R:A792	R:R:L566	1.58	No	No	0	8	9
821	A:A:E327	A:A:P328	1.57	No	No	0	4	1
822	R:R:E626	R:R:P627	1.57	No	No	0	2	5
823	B:B:C271	B:B:D290	1.56	No	No	0	5	6
824	R:R:A606	R:R:N607	1.56	No	No	0	7	9
825	R:R:I689	R:R:S692	1.55	No	No	0	6	6
826	A:A:A48	A:A:D49	1.54	No	No	0	8	6
827	A:A:A269	A:A:D272	1.54	No	No	0	9	8
828	B:B:D254	G:G:A33	1.54	Yes	No	0	9	7
829	R:R:I730	R:R:V726	1.54	No	No	0	8	8
830	R:R:I730	R:R:V734	1.54	No	No	0	8	9
831	R:R:K822	R:R:S825	1.53	No	No	0	8	8
832	B:B:A28	B:B:Q32	1.52	No	No	0	4	1
833	B:B:I33	B:B:T34	1.52	No	Yes	0	3	5
834	B:B:A56	B:B:Q75	1.52	No	Yes	0	7	9
835	G:G:A7	G:G:Q11	1.52	No	No	0	4	3
836	R:R:I728	R:R:T771	1.52	No	No	0	5	8
837	R:R:I738	R:R:T758	1.52	No	No	0	9	8
838	A:A:A298	A:A:E299	1.51	No	No	0	4	6
839	A:A:A316	A:A:E309	1.51	No	No	0	2	4
840	A:A:G355	A:A:R283	1.5	No	No	0	2	3
841	B:B:G41	B:B:R42	1.5	No	No	0	1	2
842	R:R:G561	R:R:R560	1.5	No	No	0	2	1
843	R:R:G677	R:R:R673	1.5	No	No	0	5	3
844	R:R:L691	R:R:S690	1.5	No	No	0	4	8
845	R:R:L794	R:R:S772	1.5	Yes	No	0	6	9
846	G:G:L15	G:G:V16	1.49	No	No	0	2	7
847	R:R:L556	R:R:V554	1.49	No	No	0	4	8
848	R:R:L576	R:R:V572	1.49	No	No	0	5	5
849	R:R:L591	R:R:V590	1.49	No	No	0	8	4
850	R:R:L721	R:R:V777	1.49	No	No	0	7	7
851	R:R:I728	R:R:I732	1.47	No	No	0	5	4
852	R:R:L794	R:R:T793	1.47	Yes	No	0	6	5
853	R:R:L797	R:R:T793	1.47	Yes	No	0	7	5
854	B:B:N125	B:B:T128	1.46	No	No	0	4	3
855	R:R:N702	R:R:T700	1.46	No	No	0	3	4
856	B:B:G64	B:B:Y105	1.45	No	Yes	0	5	6
857	B:B:D322	B:B:T321	1.45	No	Yes	0	1	7
858	R:R:G677	R:R:Y676	1.45	No	Yes	0	5	8
859	A:A:E15	A:A:S13	1.44	No	No	0	6	7
860	A:A:Q35	R:R:S670	1.44	No	No	0	3	7
861	A:A:K300	A:A:K305	1.44	No	No	0	9	3
862	A:A:F312	A:A:P313	1.44	No	No	0	8	6
863	R:R:E668	R:R:S667	1.44	No	No	0	8	8
864	A:A:I235	A:A:L44	1.43	No	No	0	9	9
865	A:A:I244	A:A:L282	1.43	No	Yes	0	8	9
866	A:A:I341	A:A:L266	1.43	No	No	0	8	8
867	A:A:L388	R:R:I741	1.43	No	No	0	8	8
868	R:R:I688	R:R:L685	1.43	No	No	0	4	5
869	B:B:Q175	B:B:T173	1.42	No	No	0	4	5
870	B:B:I269	B:B:N268	1.42	No	No	0	4	4
871	B:B:E172	B:B:T173	1.41	No	No	0	6	5
872	B:B:T221	G:G:E22	1.41	No	No	0	7	9
873	B:B:L252	B:B:M262	1.41	No	No	0	7	4
874	B:B:K127	B:B:N110	1.4	No	No	0	4	4
875	B:B:L7	G:G:L15	1.38	No	No	0	8	2
876	G:G:A10	G:G:R13	1.38	No	No	0	2	6
877	R:R:A559	R:R:R560	1.38	No	No	0	3	1
878	R:R:L585	R:R:L613	1.38	No	No	0	7	8
879	R:R:L804	R:R:L808	1.38	No	No	0	8	7
880	R:R:L808	R:R:L809	1.38	No	No	0	7	8
881	A:A:L282	A:A:N239	1.37	Yes	No	0	9	8
882	B:B:I18	B:B:Q17	1.37	No	No	0	7	4
883	A:A:D223	A:A:L45	1.36	No	Yes	0	9	8
884	B:B:D5	B:B:L4	1.36	No	No	0	1	4
885	B:B:D154	B:B:N155	1.35	No	No	0	6	3
886	G:G:E47	G:G:K46	1.35	No	No	0	3	1
887	R:R:R814	R:R:S811	1.32	No	No	0	9	8
888	A:A:E268	A:A:N271	1.31	No	No	0	9	5
889	R:R:R736	R:R:V737	1.31	No	No	0	7	8
890	R:R:F787	R:R:V786	1.31	No	No	0	7	5
891	A:A:D229	A:A:E230	1.3	No	No	0	8	9
892	B:B:E10	B:B:Q6	1.27	No	No	0	8	1
893	B:B:I120	B:B:R96	1.25	Yes	No	0	6	6
894	R:R:F817	R:R:K818	1.24	No	No	0	7	8
895	R:R:F817	R:R:L591	1.22	No	No	0	7	8
896	G:G:N59	G:G:R62	1.21	Yes	No	0	9	7
897	L:L:?1	R:R:S570	1.21	Yes	No	0	0	7
898	R:R:M695	R:R:Y698	1.2	No	Yes	0	2	9
899	A:A:D229	A:A:R228	1.19	No	No	0	8	9
900	B:B:D303	B:B:R42	1.19	No	No	0	2	2
901	R:R:Q740	R:R:R736	1.17	No	No	0	8	7
902	A:A:N279	A:A:W281	1.13	No	No	0	8	5
903	L:L:?1	R:R:E557	1.07	Yes	No	0	0	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:L45	2.85	4	19	8
2	A:A:K53	4.332	5	19	9
3	A:A:I207	3.1325	4	1	9
4	A:A:V214	3.6775	4	7	6
5	A:A:F219	4.215	6	7	8
6	A:A:H220	4.124	5	1	7
7	A:A:F222	7.416	5	1	7
8	A:A:V224	3.9375	4	1	9
9	A:A:K233	11.3	4	14	9
10	A:A:W234	5.1125	4	1	9
11	A:A:F246	3.835	4	0	9
12	A:A:Y263	5.852	5	21	6
13	A:A:W277	6.192	5	10	6
14	A:A:L282	4.515	4	0	9
15	A:A:N292	7.2425	4	0	9
16	A:A:L296	5.2525	4	20	6
17	A:A:F315	6.6775	4	0	6
18	A:A:Y318	6.08	4	12	6
19	A:A:E330	7.37	4	0	3
20	A:A:Y339	7.4475	4	0	3
21	A:A:F340	8.678	5	12	7
22	A:A:D343	6.4625	4	12	3
23	A:A:F345	5.0525	4	0	8
24	A:A:R356	7.3275	4	11	2
25	A:A:C359	4.2425	4	10	5
26	A:A:F363	11.0925	4	0	5
27	A:A:T364	6.43	4	15	9
28	A:A:S366	3.064	5	0	9
29	A:A:D368	7.5375	4	15	9
30	A:A:F376	7.06	4	7	8
31	A:A:D378	8.664	5	22	7
32	A:A:R385	6.832	5	11	5
33	A:A:H387	5.365	4	23	8
34	A:A:L394	6.9375	4	11	8
35	B:B:R22	7.34	4	0	6
36	B:B:T34	5.5925	4	2	5
37	B:B:V40	2.955	4	2	3
38	B:B:H54	7.162	5	8	9
39	B:B:K57	9.79	4	1	9
40	B:B:Y59	6.15	4	1	8
41	B:B:Q75	7.57	4	1	9
42	B:B:D76	9.9125	4	17	9
43	B:B:I81	4.2325	4	25	7
44	B:B:W82	6.96429	7	8	9
45	B:B:N88	7.785	4	0	7
46	B:B:K89	7.435	4	0	9
47	B:B:I93	4.8825	4	0	7
48	B:B:W99	6.555	6	1	9
49	B:B:Y105	3.328	5	0	6
50	B:B:I120	2.45	4	0	6
51	B:B:I123	3.685	4	0	6
52	B:B:H142	6.628	5	0	9
53	B:B:Y145	8.4775	4	14	8
54	B:B:F151	4.144	5	0	9
55	B:B:L168	3.5	4	6	6
56	B:B:W169	7.3225	4	0	8
57	B:B:T177	4.435	4	6	4
58	B:B:F180	7.478	5	6	7
59	B:B:L190	3.6025	4	0	5
60	B:B:F199	4.52667	6	6	9
61	B:B:L210	4.558	5	0	5
62	B:B:W211	11.452	5	6	8
63	B:B:D212	8.065	4	16	9
64	B:B:R219	6.615	4	16	5
65	B:B:Q220	8.9625	4	0	7
66	B:B:F222	11.3375	4	4	8
67	B:B:H225	8.172	5	4	9
68	B:B:S227	4.1675	4	26	6
69	B:B:F234	4.5075	4	0	5
70	B:B:F235	4.75	7	0	6
71	B:B:F241	8.065	4	4	6
72	B:B:C250	3.5625	4	0	8
73	B:B:F253	12.222	5	4	6
74	B:B:D254	4.135	4	0	9
75	B:B:D258	9.7125	4	4	7
76	B:B:Q259	4.1175	4	0	6
77	B:B:Y264	6.4875	4	0	5
78	B:B:S281	5.07	4	2	9
79	B:B:R283	4.94	7	2	9
80	B:B:Y289	6.094	5	0	7
81	B:B:N295	5.65	4	27	6
82	B:B:D298	7.3575	4	2	9
83	B:B:L300	6.79	5	2	6
84	B:B:H311	7.002	5	3	9
85	B:B:N313	4.094	5	3	7
86	B:B:V315	3.0975	4	3	7
87	B:B:T321	6.71	4	24	7
88	B:B:T329	4.534	5	3	8
89	B:B:S331	6.92	4	3	9
90	B:B:W332	11.0725	4	0	9
91	B:B:D333	8.44	5	3	9
92	B:B:K337	5.425	4	3	6
93	B:B:W339	7.49	5	3	9
94	G:G:D48	6.576	5	2	9
95	G:G:L51	5.1775	4	2	6
96	G:G:N59	4.932	5	13	9
97	G:G:P60	4.955	4	13	9
98	G:G:F61	3.728	5	13	8
99	L:L:?1	3.782	5	0	0
100	R:R:H562	15.362	5	28	7
101	R:R:R601	8.885	6	5	8
102	R:R:Y602	6.83143	7	5	8
103	R:R:G628	1.9425	4	31	7
104	R:R:Y641	3.2875	4	0	7
105	R:R:F642	4.3325	4	0	8
106	R:R:F647	6.25	4	0	9
107	R:R:W649	9.376	5	30	9
108	R:R:E653	5.734	5	9	9
109	R:R:V664	3.5425	4	23	9
110	R:R:F665	7.1175	4	7	8
111	R:R:Y675	6.68	4	0	8
112	R:R:Y676	3.065	4	30	8
113	R:R:P683	2.85	4	0	8
114	R:R:Y698	5.7425	4	32	9
115	R:R:W705	9.39	4	0	9
116	R:R:P767	5.4125	4	0	9
117	R:R:I768	6.824	5	9	8
118	R:R:W773	9.0525	4	0	9
119	R:R:L794	2.06	4	0	6
120	R:R:L797	3.498	5	0	7
121	R:R:E812	5.0625	4	5	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:N88	B:B:T86	64.7143	13.16	Yes	No	0	7	6
2	A:A:S23	B:B:N88	68.0506	8.94	No	Yes	0	7	7
3	A:A:S23	B:B:K89	68.5994	3.06	No	Yes	0	7	9
4	B:B:K89	B:B:W82	70.7923	12.76	Yes	Yes	0	9	9
5	B:B:H54	B:B:W82	74.0456	3.17	Yes	Yes	8	9	9
6	B:B:H54	B:B:I58	76.2439	7.95	Yes	No	0	9	9
7	B:B:G330	B:B:I58	76.7892	3.53	No	No	0	5	9
8	B:B:G330	B:B:T329	77.3344	3.64	No	Yes	0	5	8
9	B:B:H311	B:B:T329	60.9245	6.85	Yes	Yes	3	9	8
10	B:B:H311	B:B:S331	33.1639	11.16	Yes	Yes	3	9	9
11	B:B:N313	B:B:S331	64.0667	2.98	Yes	Yes	3	7	9
12	B:B:N313	B:B:W332	98.7574	5.65	Yes	Yes	0	7	9
13	B:B:K57	B:B:W332	100	16.24	Yes	Yes	0	9	9
14	B:B:K57	B:B:Q75	28.9287	10.85	Yes	Yes	1	9	9
15	B:B:Q75	B:B:W99	30.6869	4.38	Yes	Yes	1	9	9
16	B:B:T329	B:B:V315	30.4216	3.17	Yes	Yes	3	8	7
17	B:B:S331	B:B:V315	30.7571	3.23	Yes	Yes	3	9	7
18	B:B:D333	B:B:H311	33.2608	6.3	Yes	Yes	3	9	9
19	B:B:D333	B:B:N313	34.0697	6.73	Yes	Yes	3	9	7
20	B:B:K57	B:B:Y59	71.317	2.39	Yes	Yes	1	9	8
21	A:A:C237	B:B:Y59	65.1882	2.69	No	Yes	1	8	8
22	A:A:C237	A:A:F238	63.322	9.78	No	No	1	8	9
23	A:A:F238	A:A:W234	91.4317	4.01	No	Yes	1	9	9
24	A:A:R231	A:A:W234	92.4909	4	No	Yes	0	9	9
25	A:A:D272	A:A:R231	91.3654	2.38	No	No	0	8	9
26	A:A:D272	A:A:F246	91.0421	4.78	No	Yes	0	8	9
27	A:A:F246	A:A:F273	87.9245	4.29	Yes	No	0	9	9
28	A:A:F273	A:A:V287	87.7582	3.93	No	No	0	9	6
29	A:A:V287	A:A:W277	76.9616	2.45	No	Yes	10	6	6
30	A:A:H357	A:A:W277	79.9603	15.87	No	Yes	0	7	6
31	A:A:H357	A:A:S286	76.7974	2.79	No	No	0	7	8
32	A:A:I382	A:A:S286	76.6093	6.19	No	No	0	6	8
33	A:A:D378	A:A:I382	75.9688	2.8	Yes	No	22	7	6
34	A:A:D378	A:A:N377	64.5139	2.69	Yes	No	0	7	4
35	A:A:N377	A:A:R373	64.3118	10.85	No	No	0	4	5
36	A:A:F376	A:A:R373	64.1094	4.28	Yes	No	0	8	5
37	A:A:F376	R:R:F665	60.9621	11.79	Yes	Yes	7	8	8
38	A:A:R380	R:R:F665	60.6355	4.28	No	Yes	0	7	8
39	A:A:R380	R:R:V664	60.4291	3.92	No	Yes	0	7	9
40	A:A:H387	R:R:V664	59.1583	2.77	Yes	Yes	23	8	9
41	A:A:F238	B:B:W99	28.2649	9.02	No	Yes	1	9	9
42	A:A:D378	A:A:H362	14.4228	5.04	Yes	No	0	7	9
43	A:A:H362	A:A:R374	14.1715	18.05	No	No	0	9	4
44	A:A:R374	A:A:T364	13.9199	6.47	No	Yes	0	4	9
45	A:A:D368	A:A:T364	13.1579	5.78	Yes	Yes	15	9	9
46	A:A:C365	A:A:D368	12.4107	3.11	No	Yes	0	8	9
47	A:A:C365	A:A:S366	12.1574	1.72	No	Yes	0	8	9
48	B:B:M101	B:B:Y59	83.8362	5.99	No	Yes	0	9	8
49	B:B:M101	B:B:Y145	83.8005	2.39	No	Yes	0	9	8
50	B:B:G162	B:B:Y145	11.7566	5.79	No	Yes	14	9	8
51	B:B:G144	B:B:G162	16.0509	2.11	No	No	0	8	9
52	A:A:K233	B:B:Y145	80.9788	11.94	Yes	Yes	14	9	8
53	A:A:K233	B:B:C204	85.4237	6.47	Yes	No	0	9	7
54	A:A:C359	A:A:V287	10.63	3.42	Yes	No	10	5	6
55	A:A:C359	A:A:L346	12.143	3.17	Yes	No	10	5	4
56	A:A:L346	A:A:P361	13.793	3.28	No	No	0	4	5
57	A:A:P361	A:A:R342	13.5047	4.32	No	No	0	5	4
58	A:A:H387	R:R:M660	58.3533	7.88	Yes	No	0	8	8
59	A:A:Y391	R:R:M660	12.2809	3.59	No	No	0	4	8
60	R:R:H656	R:R:M660	46.3168	3.94	No	No	0	8	8
61	B:B:C204	B:B:D228	85.3659	3.11	No	No	0	7	9
62	B:B:D228	B:B:S227	85.0462	4.42	No	Yes	26	9	6
63	B:B:S227	B:B:S245	61.5213	4.89	Yes	No	0	6	9
64	B:B:H225	B:B:S245	61.4422	13.95	Yes	No	0	9	9
65	B:B:H225	B:B:R251	23.3016	14.67	Yes	No	4	9	8
66	B:B:E260	B:B:R251	46.3359	10.47	No	No	0	6	8
67	B:B:D247	B:B:S227	23.6116	2.94	No	Yes	0	9	6
68	B:B:D247	B:B:T249	23.3912	4.34	No	No	0	9	6
69	B:B:R251	B:B:T249	23.2778	7.76	No	No	4	8	6
70	B:B:H225	B:B:T243	37.7791	6.85	Yes	No	4	9	8
71	B:B:F241	B:B:T243	37.5503	2.59	Yes	No	4	6	8
72	B:B:F222	B:B:F241	17.6019	7.5	Yes	Yes	4	8	6
73	B:B:D258	B:B:F222	17.3692	11.94	Yes	Yes	4	7	8
74	B:B:F241	B:B:F253	19.9911	17.15	Yes	Yes	4	6	6
75	B:B:D258	B:B:F253	52.1126	8.36	Yes	Yes	4	7	6
76	B:B:E260	B:B:F253	39.847	11.66	No	Yes	0	6	6
77	B:B:D83	B:B:T86	62.5256	2.89	No	No	0	8	6
78	B:B:D83	B:B:Y85	51.4627	3.45	No	No	0	8	4
79	B:B:Y85	G:G:P60	48.0873	4.17	No	Yes	0	4	9
80	B:B:M325	G:G:P60	41.4054	3.35	No	Yes	0	5	9
81	B:B:M325	G:G:P49	36.3649	3.35	No	No	0	5	7
82	G:G:D48	G:G:P49	34.6807	3.22	Yes	No	0	9	7
83	B:B:S281	G:G:D48	20.4753	10.31	Yes	Yes	2	9	9
84	B:B:G282	B:B:S281	20.0002	3.71	No	Yes	0	9	9
85	B:B:F235	B:B:G282	19.4326	3.01	Yes	No	0	6	9
86	B:B:F235	B:B:F278	14.8834	9.65	Yes	No	0	6	7
87	B:B:F278	B:B:L285	14.3137	9.74	No	No	0	7	6
88	B:B:L285	B:B:Y264	13.1737	5.86	No	Yes	0	6	5
89	G:G:D48	G:G:L51	12.5151	10.86	Yes	Yes	2	9	6
90	B:B:R283	G:G:L51	10.8932	2.43	Yes	Yes	2	9	6
91	B:B:D83	B:B:R68	10.8975	15.48	No	No	0	8	5
92	B:B:D163	B:B:G144	15.0238	3.35	No	No	0	9	8
93	B:B:D163	B:B:H142	14.5089	5.04	No	Yes	0	9	9
94	B:B:H142	B:B:W169	11.6314	4.23	Yes	Yes	0	9	8
95	B:B:T159	B:B:W169	10.0797	3.64	No	Yes	0	9	8
96	B:B:D258	B:B:Q220	66.114	7.83	Yes	Yes	0	7	7
97	B:B:L210	B:B:Q220	64.0348	6.65	Yes	Yes	0	5	7
98	B:B:L210	B:B:R219	58.2748	4.86	Yes	Yes	0	5	5
99	B:B:D212	B:B:R219	28.3533	11.91	Yes	Yes	16	9	5
100	B:B:D212	B:B:R214	27.8354	2.38	Yes	No	16	9	9
101	B:B:R214	B:B:V213	54.5945	5.23	No	No	0	9	4
102	B:B:F199	B:B:V213	53.5296	3.93	Yes	No	0	9	4
103	B:B:E215	B:B:R219	28.353	3.49	No	Yes	16	3	5
104	B:B:E215	B:B:R214	27.8238	4.65	No	No	16	3	9
105	B:B:F199	B:B:V158	11.7875	2.62	Yes	No	0	9	5
106	B:B:L168	B:B:V158	10.7151	2.98	Yes	No	0	6	5
107	B:B:L168	B:B:T177	17.1633	4.42	Yes	Yes	6	6	4
108	B:B:F180	B:B:F199	13.9279	7.5	Yes	Yes	6	7	9
109	B:B:F180	B:B:L168	10.7385	3.65	Yes	Yes	6	7	6
110	B:B:F199	B:B:W211	17.1427	7.02	Yes	Yes	6	9	8
111	R:R:H656	R:R:Y675	39.1142	11.98	No	Yes	0	8	8
112	R:R:I604	R:R:Y675	37.7583	6.04	No	Yes	0	9	8
113	R:R:I604	R:R:W649	30.3736	5.87	No	Yes	0	9	9
114	R:R:W649	R:R:W680	28.0089	14.99	Yes	No	0	9	8
115	R:R:W680	R:R:Y641	24.5482	2.89	No	Yes	0	8	7
116	R:R:F642	R:R:Y641	20.2294	2.06	Yes	Yes	0	8	7
117	R:R:F642	R:R:L618	19.4966	2.44	Yes	No	0	8	7
118	R:R:L618	R:R:M635	19.0069	4.24	No	No	0	7	6
119	R:R:M635	R:R:S622	16.0501	7.67	No	No	0	6	8
120	R:R:S622	R:R:W705	15.8023	3.71	No	Yes	0	8	9
121	L:L:?1	R:R:W705	12.5599	10.09	Yes	Yes	0	0	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:Q563	3.22	0	Yes	No	0	4	0	1
L:L:?1	R:R:W705	10.09	0	Yes	Yes	0	9	0	1
L:L:?1	R:R:N795	3.32	0	Yes	No	0	9	0	1
R:R:L558	R:R:Q563	9.32	28	No	No	5	4	2	1
R:R:L619	R:R:W705	3.42	0	No	Yes	9	9	2	1
R:R:S622	R:R:W705	3.71	0	No	Yes	8	9	2	1
R:R:N703	R:R:W705	20.34	0	No	Yes	7	9	2	1
R:R:N795	R:R:W773	15.82	0	No	Yes	9	9	1	2
R:R:N795	R:R:Q798	3.96	0	No	No	9	9	1	2
L:L:?1	R:R:S570	1.21	0	Yes	No	0	7	0	1
L:L:?1	R:R:E557	1.07	0	Yes	No	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
30.00	Single	6LI0	C17	6LI0-GPR52-C17
30.00	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
27.27	Single	5U09	Taranabant	5U09-CB₁-Taranabant
25.00	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
25.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
25.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
23.08	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
23.08	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
22.22	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
22.22	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
21.43	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
21.43	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
21.43	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
20.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
20.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
20.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
20.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
20.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
20.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
20.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042
20.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
20.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
20.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
20.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
20.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626
20.00	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
20.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
20.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
20.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
20.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
20.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
20.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
20.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
20.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
20.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
20.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
20.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
20.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
20.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
20.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
20.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
20.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
20.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
20.00	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
20.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
20.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
20.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
20.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
20.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
20.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
20.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
20.00	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
20.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
20.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
20.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
20.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
20.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
20.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
20.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
20.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
20.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
20.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
20.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
20.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
20.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
20.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
20.00	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
20.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
20.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
20.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
20.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
20.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
20.00	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
20.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
20.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
20.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
20.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
20.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
20.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
20.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
20.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
20.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
20.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
20.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
20.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
20.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
20.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
20.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
20.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
20.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
20.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
20.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
20.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
20.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
20.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
20.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
20.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
20.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
20.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
20.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
20.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
20.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
20.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
20.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
20.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
20.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
20.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
20.00	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
20.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
20.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
20.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
20.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
20.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
20.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
20.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
20.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
20.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
20.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
20.00	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
20.00	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
20.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
20.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
20.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
20.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
20.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
20.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
20.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
20.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
20.00	Single	8WG9	(2S)-2-amino-4-phosphonobutanoic acid	8WG9-mGlu4; mGlu2-(2S)-2-amino-4-phosphonobutanoic acid
20.00	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
20.00	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
20.00	Single	8WGC	LY379268	8WGC-mGlu4; mGlu2-LY379268
20.00	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
20.00	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
20.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
20.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
20.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	8WVX	Norrin	8WVX-LGR4-Norrin
20.00	Single	8WVY	Norrin	8WVY-LGR4-Norrin
20.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
20.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
20.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
20.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
20.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
20.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
20.00	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
20.00	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
20.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
20.00	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
20.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
20.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
20.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
20.00	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
20.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
20.00	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
20.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
20.00	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
20.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
20.00	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
20.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
20.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
20.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
20.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
20.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
20.00	Single	9KHH	Norrin	9KHH-LGR4-Norrin
20.00	Single	9S37	NB21	9S37-LGR4-NB21
20.00	Single	9UTB	Sucralose	9UTB-TAS1R2; TAS1R3-Sucralose
20.00	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
19.05	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
19.05	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
18.75	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
18.75	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
18.75	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
18.75	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
18.75	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
18.75	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
18.18	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
18.18	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
18.18	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
18.18	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
18.18	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
17.65	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
17.65	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
17.65	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
17.65	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
17.65	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
17.65	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
17.39	Single	6FJ3	PTH	6FJ3-PTH1-PTH
17.39	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
17.39	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
16.67	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
16.67	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
16.67	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
16.67	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
16.67	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
16.67	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
16.67	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
16.67	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
16.67	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
16.67	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
16.67	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
16.67	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
16.67	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
16.67	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
16.67	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
16.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
16.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
16.67	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
16.67	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
16.67	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
16.67	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
16.67	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
16.67	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
16.67	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
16.67	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
16.67	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
16.67	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
16.67	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
16.67	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
16.67	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
16.00	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
16.00	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
16.00	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
15.79	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
15.79	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
15.79	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
15.79	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
15.79	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
15.79	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
15.38	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
15.38	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
15.38	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
15.38	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
15.38	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
15.38	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
15.38	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
15.38	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
15.38	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
15.00	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
15.00	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
15.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
15.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
15.00	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
15.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
14.29	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
14.29	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
14.29	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
14.29	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
14.29	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
14.29	Single	6D27	CAY10471	6D27-DP₂-CAY10471
14.29	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
14.29	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
14.29	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
14.29	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
14.29	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
14.29	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
14.29	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
14.29	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
14.29	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
14.29	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
14.29	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
14.29	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
14.29	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
14.29	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
14.29	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
14.29	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
13.64	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
13.64	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
13.64	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
13.64	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
13.64	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
13.64	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
13.64	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
13.64	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
13.64	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
13.64	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
13.64	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
13.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
13.33	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
13.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
13.33	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
13.33	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
13.33	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
13.33	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
13.33	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
13.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
13.04	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
13.04	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
13.04	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
13.04	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
13.04	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
13.04	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
13.04	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
13.04	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
13.04	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
13.04	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
13.04	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
13.04	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
13.04	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
13.04	Consensus	pac_on	Orthosteric Ligand	pac1_on
13.04	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
13.04	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
12.50	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
12.50	Single	5V56	TC114	5V56-SMO-TC114
12.50	Single	5V57	TC114	5V57-SMO-TC114
12.50	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.50	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
12.50	Single	6OS1	TRV026	6OS1-AT₁-TRV026
12.50	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
12.50	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
12.50	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
12.50	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
12.50	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
12.50	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
12.50	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
12.50	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
12.50	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
12.50	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
12.50	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
12.50	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
12.50	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
12.50	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
12.50	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
12.50	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
12.50	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
12.50	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
12.50	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
12.50	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
12.50	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
12.50	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
12.50	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
12.50	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
12.50	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
12.00	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
12.00	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
12.00	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
12.00	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
12.00	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
12.00	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
12.00	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.00	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
12.00	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
12.00	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
12.00	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
12.00	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
11.76	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
11.76	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
11.76	Single	6OS2	TRV026	6OS2-AT₁-TRV026
11.76	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
11.76	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
11.76	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
11.76	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
11.76	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
11.76	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
11.76	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
11.76	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
11.76	Single	8XQJ	JN241	8XQJ-Apelin-JN241
11.76	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
11.76	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
11.76	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
11.76	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.76	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
11.76	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
11.76	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
11.76	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
11.76	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
11.76	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
11.76	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
11.76	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
11.76	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
11.54	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
11.54	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
11.54	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
11.54	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
11.54	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
11.54	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
11.54	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
11.54	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
11.54	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.54	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
11.54	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
11.54	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
11.54	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
11.54	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
11.54	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
11.54	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
11.11	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
11.11	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
11.11	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
11.11	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
11.11	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
11.11	Single	7V68	LY2119620	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
11.11	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
11.11	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
11.11	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
11.11	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
11.11	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
11.11	Single	8HS2	Fab046	8HS2-GPR20-Fab046
11.11	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
11.11	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
11.11	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
11.11	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
11.11	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
11.11	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
11.11	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
11.11	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
11.11	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
11.11	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
11.11	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
11.11	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
10.71	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
10.71	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
10.71	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
10.71	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
10.53	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
10.53	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
10.53	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
10.53	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
10.53	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
10.53	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
10.53	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
10.53	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
10.53	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
10.53	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Single	8XQJ	JN241	8XQJ-Apelin-JN241
10.53	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
10.53	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
10.53	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
10.53	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
10.53	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
10.53	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
10.34	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
10.34	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
10.34	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
10.34	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
10.34	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
10.34	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
10.00	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
10.00	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
10.00	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
10.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
10.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
10.00	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
10.00	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
10.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
10.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
10.00	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
10.00	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
10.00	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
10.00	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
10.00	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
10.00	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
10.00	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
10.00	Single	8Y02	Retinal	8Y02-OPN1SW-Retinal-Gi1/β1/γ2
10.00	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
10.00	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
10.00	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.00	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.00	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
10.00	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
10.00	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
10.00	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
10.00	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
10.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
10.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
10.00	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
10.00	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
9.68	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.68	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
9.68	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
9.52	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
9.52	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
9.52	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
9.52	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
9.52	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
9.52	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
9.52	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
9.52	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
9.52	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
9.52	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
9.52	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
9.52	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
9.52	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
9.52	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
9.52	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
9.52	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
9.38	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
9.09	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
9.09	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
9.09	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
9.09	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
9.09	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
9.09	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
9.09	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
9.09	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
9.09	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
9.09	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
9.09	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
9.09	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
9.09	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
9.09	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
9.09	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
9.09	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
9.09	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
9.09	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
9.09	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
9.09	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
9.09	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
9.09	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
9.09	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
9.09	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9JHJ	C18:0 Ceramide	9JHJ-FPR2-ALX-C18:0 Ceramide-Gi1/β1/γ2
9.09	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
9.09	Single	9LRC	Histamine	9LRC-H₄-Histamine
9.09	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
9.09	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
9.09	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
9.09	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
9.09	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
9.09	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
9.09	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
9.09	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
9.09	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
9.09	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
9.09	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
9.09	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
9.09	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
9.09	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
8.70	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
8.70	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
8.70	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
8.70	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
8.70	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
8.70	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
8.70	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
8.70	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
8.70	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
8.70	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
8.70	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
8.70	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
8.70	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
8.70	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
8.70	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
8.70	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
8.70	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
8.70	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
8.70	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
8.70	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
8.70	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
8.70	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
8.70	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
8.70	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
8.70	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
8.70	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
8.57	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
8.33	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
8.33	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
8.33	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
8.33	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
8.33	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
8.33	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
8.33	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
8.33	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
8.33	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
8.33	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
8.33	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
8.33	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
8.33	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
8.33	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
8.33	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
8.33	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
8.33	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
8.33	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
8.33	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
8.33	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
8.33	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
8.33	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
8.33	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
8.33	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
8.33	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
8.33	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
8.33	Single	8YKD	Dehydroepiandrosterone	8YKD-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
8.33	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
8.33	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
8.33	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
8.33	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
8.33	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
8.33	Single	9B9Y	7DY	9B9Y-CB₁-7DY
8.33	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
8.33	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
8.33	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
8.33	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
8.33	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
8.33	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
8.33	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
8.33	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
8.33	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
8.33	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
8.33	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
8.00	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
8.00	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
8.00	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
8.00	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
8.00	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
8.00	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
8.00	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
8.00	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
8.00	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
8.00	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
8.00	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
8.00	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
8.00	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
8.00	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
8.00	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
8.00	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
8.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
8.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
8.00	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
7.69	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
7.69	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
7.69	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
7.69	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
7.69	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
7.69	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
7.69	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
7.69	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
7.69	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
7.69	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
7.69	Single	6AKX	A4R	6AKX-CCR5-A4R
7.69	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
7.69	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
7.69	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
7.69	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
7.69	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
7.69	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
7.69	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
7.69	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
7.69	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
7.69	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
7.69	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
7.69	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
7.69	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
7.69	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
7.69	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
7.69	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
7.69	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
7.69	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
7.69	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
7.69	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
7.69	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
7.69	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
7.69	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
7.69	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
7.69	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
7.69	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.69	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
7.69	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
7.69	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
7.69	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
7.69	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
7.69	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
7.69	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
7.69	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
7.69	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
7.69	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
7.69	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
7.69	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
7.69	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
7.69	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
7.69	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
7.69	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
7.69	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
7.69	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.69	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
7.69	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
7.69	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
7.69	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
7.69	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
7.69	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
7.69	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
7.69	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
7.69	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
7.69	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
7.69	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
7.69	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
7.69	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
7.69	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.69	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
7.69	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
7.69	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
7.69	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
7.69	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
7.69	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
7.69	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.69	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.69	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
7.69	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
7.69	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
7.69	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
7.69	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.69	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
7.41	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
7.41	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
7.41	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
7.41	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
7.41	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
7.41	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
7.41	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
7.41	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
7.41	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
7.41	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
7.41	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
7.41	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
7.41	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
7.41	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
7.41	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
7.41	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
7.14	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
7.14	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
7.14	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
7.14	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
7.14	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
7.14	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
7.14	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
7.14	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
7.14	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
7.14	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
7.14	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
7.14	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
7.14	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
7.14	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
7.14	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
7.14	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
7.14	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
7.14	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
7.14	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
7.14	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
7.14	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
7.14	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
7.14	Single	7F61	PF-03654746	7F61-H₃-PF-03654746
7.14	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
7.14	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
7.14	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
7.14	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
7.14	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
7.14	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
7.14	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
7.14	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
7.14	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
7.14	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
7.14	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
7.14	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
7.14	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
7.14	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
7.14	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
7.14	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
7.14	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
7.14	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
7.14	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
7.14	Single	8K9L	Damgo	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
7.14	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
7.14	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
7.14	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
7.14	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
7.14	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
7.14	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
7.14	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
7.14	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
7.14	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
7.14	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Gi1/β1/γ2
7.14	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
7.14	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
7.14	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
7.14	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
7.14	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
7.14	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
7.14	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
7.14	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
7.14	Consensus	hca_on	Orthosteric Ligand	hca2_on
7.14	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
7.14	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
7.14	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
6.90	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
6.90	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
6.90	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
6.90	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
6.90	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
6.90	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
6.90	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
6.67	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
6.67	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
6.67	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
6.67	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
6.67	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
6.67	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
6.67	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
6.67	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
6.67	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
6.67	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
6.67	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
6.67	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
6.67	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
6.67	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
6.67	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
6.67	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
6.67	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
6.67	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
6.67	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
6.67	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
6.67	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
6.67	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
6.67	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
6.67	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
6.67	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
6.67	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
6.67	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
6.67	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
6.67	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
6.67	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
6.67	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
6.67	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
6.67	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
6.67	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
6.67	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
6.67	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
6.67	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
6.67	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
6.67	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
6.67	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
6.67	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
6.67	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
6.67	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
6.67	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
6.67	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
6.67	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
6.67	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
6.67	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
6.67	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
6.67	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
6.67	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
6.67	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
6.67	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
6.67	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
6.67	Single	9JEA	Atropine	9JEA-M₁-Atropine
6.67	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
6.67	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.67	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
6.67	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
6.67	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
6.67	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
6.67	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
6.67	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
6.67	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
6.67	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
6.67	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
6.67	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
6.67	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
6.67	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
6.67	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
6.67	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
6.67	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
6.67	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
6.67	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
6.67	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
6.67	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
6.45	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
6.45	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
6.25	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
6.25	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
6.25	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
6.25	Single	5C1M	BU72	5C1M-μ-BU72
6.25	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
6.25	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
6.25	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
6.25	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
6.25	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
6.25	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
6.25	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
6.25	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
6.25	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
6.25	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
6.25	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
6.25	Single	7C4S	S1P	7C4S-S1P₃-S1P
6.25	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
6.25	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
6.25	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
6.25	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
6.25	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
6.25	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
6.25	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
6.25	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
6.25	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
6.25	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
6.25	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
6.25	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
6.25	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
6.25	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
6.25	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
6.25	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
6.25	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
6.25	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
6.25	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
6.25	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
6.25	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
6.25	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
6.25	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
6.25	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
6.25	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
6.25	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
6.25	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
6.25	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
6.25	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
6.25	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
6.25	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
6.25	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
6.25	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
6.25	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
6.25	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
6.25	Single	9GE2	ML184	9GE2-GPR55-ML184-chim(NtGi1-G13)/β1/γ2
6.25	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
6.25	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
6.25	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
6.25	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
6.25	Consensus	dp_off	Orthosteric Ligand	dp2_off
6.25	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
6.25	Consensus	ep_off	Orthosteric Ligand	ep4_off
6.25	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
6.25	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
6.25	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
6.25	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
6.25	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
6.25	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
6.25	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
6.25	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
6.25	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
6.25	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
6.25	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
6.06	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
6.06	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.88	Single	2YDV	NECA	2YDV-A_2A-NECA
5.88	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
5.88	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
5.88	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
5.88	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
5.88	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
5.88	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
5.88	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
5.88	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
5.88	Single	5G53	NECA	5G53-A_2A-NECA-Gs
5.88	Single	5TZR	MK8666	5TZR-FFA1-MK8666
5.88	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.88	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.88	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
5.88	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
5.88	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.88	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.88	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
5.88	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
5.88	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
5.88	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.88	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
5.88	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
5.88	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
5.88	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
5.88	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
5.88	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
5.88	Single	7P2L	4YI	7P2L-mGlu₅-4YI
5.88	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
5.88	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
5.88	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
5.88	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
5.88	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.88	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
5.88	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.88	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
5.88	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
5.88	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
5.88	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
5.88	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
5.88	Single	8E0G	BU72	8E0G-μ-BU72
5.88	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
5.88	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
5.88	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
5.88	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
5.88	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
5.88	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
5.88	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
5.88	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
5.88	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
5.88	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
5.88	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.88	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
5.88	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.88	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
5.88	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
5.88	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
5.88	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
5.88	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.88	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
5.88	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
5.88	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
5.88	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
5.88	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
5.88	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
5.88	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9CLW	TUG-1375	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
5.88	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
5.88	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
5.88	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.88	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
5.88	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.88	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.88	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
5.88	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
5.88	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
5.88	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
5.88	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
5.88	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
5.88	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
5.88	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
5.88	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
5.88	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
5.88	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
5.88	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.88	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.71	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
5.56	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
5.56	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
5.56	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
5.56	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
5.56	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
5.56	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
5.56	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
5.56	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
5.56	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
5.56	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
5.56	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
5.56	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
5.56	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
5.56	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
5.56	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
5.56	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
5.56	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
5.56	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
5.56	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
5.56	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
5.56	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
5.56	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
5.56	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
5.56	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
5.56	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
5.56	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.56	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
5.56	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
5.56	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
5.56	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
5.56	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
5.56	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
5.56	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
5.56	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
5.56	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
5.56	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
5.56	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
5.56	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
5.56	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.56	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
5.56	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
5.56	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
5.56	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
5.56	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
5.56	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
5.56	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
5.56	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.56	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
5.56	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
5.56	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
5.56	Single	8Y6W	TUG-1375	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
5.56	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
5.56	Single	9CM3	TUG-1375	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
5.56	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
5.56	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
5.56	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
5.56	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
5.56	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.56	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
5.56	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
5.56	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
5.56	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
5.56	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
5.56	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
5.56	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
5.56	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
5.56	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
5.56	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
5.56	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
5.56	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
5.56	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.56	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.56	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
5.26	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
5.26	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
5.26	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
5.26	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
5.26	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
5.26	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
5.26	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
5.26	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
5.26	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
5.26	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
5.26	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
5.26	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
5.26	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
5.26	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
5.26	Single	7EZC	UKA	7EZC-A_2A-UKA
5.26	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
5.26	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
5.26	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
5.26	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
5.26	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
5.26	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
5.26	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
5.26	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
5.26	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
5.26	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
5.26	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
5.26	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
5.26	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
5.26	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
5.26	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
5.26	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
5.26	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
5.26	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
5.26	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
5.26	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
5.26	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
5.26	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
5.26	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
5.26	Single	9AS0	2-bromo-LSD	9AS0-5-HT_2A-2-bromo-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
5.26	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
5.26	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
5.26	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
5.26	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
5.26	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
5.26	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
5.26	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
5.26	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
5.26	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
5.26	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
5.26	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
5.26	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
5.26	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
5.26	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
5.13	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
5.00	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
5.00	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
5.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
5.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
5.00	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
5.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
5.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
5.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
5.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
5.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
5.00	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
5.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
5.00	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
5.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
5.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
5.00	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
5.00	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.00	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
5.00	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
5.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
5.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
5.00	Single	9CM7	TUG-1375	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
5.00	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
5.00	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
5.00	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
5.00	Single	9NS9	TUG-1375	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
5.00	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
5.00	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
5.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
5.00	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
5.00	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
5.00	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
5.00	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.76	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
4.76	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
4.76	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
4.76	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
4.76	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
4.76	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
4.76	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
4.76	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
4.76	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
4.76	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
4.76	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
4.76	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.76	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.76	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.76	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.76	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
4.76	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
4.76	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
4.76	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
4.76	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
4.76	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
4.76	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
4.76	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
4.76	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
4.76	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
4.76	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
4.76	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.76	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.76	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
4.76	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
4.76	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
4.76	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.76	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
4.76	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.55	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
4.55	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
4.55	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
4.55	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
4.55	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
4.55	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
4.55	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
4.55	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
4.55	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
4.55	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
4.55	Single	9E82	SDF-1-beta	9E82-ACKR3-SDF-1-β-Arrestin2
4.55	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
4.55	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
4.55	Single	9IQR	Muscarinic toxin 3	9IQR-α_2a-Muscarinic toxin 3
4.55	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
4.55	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
4.55	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
4.55	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
4.55	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
4.55	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
4.55	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.55	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
4.55	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
4.35	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
4.35	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
4.35	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
4.35	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
4.35	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
4.35	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
4.35	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
4.35	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
4.35	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
4.35	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
4.35	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.35	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
4.35	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
4.35	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
4.35	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
4.35	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
4.35	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.35	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
4.35	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
4.35	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
4.35	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
4.35	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
4.35	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
4.17	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
4.17	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
4.17	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
4.17	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
4.17	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
4.17	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
4.17	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
4.17	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.17	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3
4.17	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
4.17	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
4.17	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
4.17	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
4.17	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
4.17	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
4.00	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
4.00	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
4.00	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
4.00	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
4.00	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.00	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
4.00	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
4.00	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
4.00	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
4.00	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
4.00	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
3.85	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.85	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
3.85	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
3.85	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
3.85	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.85	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.85	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
3.70	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
3.70	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
3.70	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
3.70	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
3.70	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
3.70	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
3.70	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3
3.70	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
3.70	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
3.57	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
3.57	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
3.57	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
3.57	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.57	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.45	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
3.45	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
3.45	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.33	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.33	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.23	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2

PDB Summary
PDB	8X9S
Class	B2
SubFamily	Adhesion
Type	Adhesion
SubType	ADGRD1
Species	Homo Sapiens
Ligand	5alpha-DHT
Other Ligand(s)	-
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	3.49
Date	2025-02-12
D.O.I.	doi.org/10.1016/j.cell.2025.01.006

Net Summary
I_min	2.38
Number of Linked Nodes	809
Number of Links	903
Number of Hubs	121
Number of Links mediated by Hubs	454
Number of Communities	32
Number of Nodes involved in Communities	160
Number of Links involved in Communities	203

Path Summary
Number Of Nodes in MetaPath	122
Number Of Links MetaPath	121
Number of Shortest Paths	1521182
Length Of Smallest Path	3
Average Path Length	37.8505
Length of Longest Path	80
Minimum Path Strength	1.14
Average Path Strength	6.00046
Maximum Path Strength	23.265
Minimum Path Correlation	0.7
Average Path Correlation	0.983606
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.96078
Average % Of Corr. Nodes	40.3296
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.7564
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• peptide hormone receptor binding • protein binding • binding • corticotropin-releasing hormone receptor binding • signaling receptor binding • G protein-coupled receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • mu-type opioid receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • ionotropic glutamate receptor binding • glutamate receptor binding • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • molecular function regulator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • insulin-like growth factor receptor binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • intracellular anatomical structure • cytoplasm • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell surface receptor signaling pathway • multicellular organismal process • system process • nervous system process • neuromuscular process • regulation of system process • skeletal muscle contraction • muscle contraction • muscle system process • regulation of muscle system process • striated muscle contraction • multicellular organismal movement • musculoskeletal movement • regulation of striated muscle contraction • regulation of muscle contraction • regulation of skeletal muscle contraction • regulation of multicellular organismal process • membrane-bounded organelle • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • intracellular organelle lumen • nuclear speck • ribonucleoprotein granule • intracellular organelle • nuclear body • nucleoplasm • organelle lumen • organelle • membraneless organelle • supramolecular complex • nuclear ribonucleoprotein granule • nuclear lumen • cytosol • protein binding • binding • G-protein beta-subunit binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • sensory perception of chemical stimulus • sensory perception • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to stress • response to hypoxia • response to stress • response to oxygen levels • response to abiotic stimulus • cell population proliferation • phospholipase C-activating G protein-coupled receptor signaling pathway • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • synapse • cell junction • cell body
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	DHT
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	DHT
Name	Stanolone
Synonyms	17beta-Hydroxy-5alpha-androstan-3-one
Identifier
Formula	C19 H30 O2
Molecular Weight	290.44
SMILES
PubChem	10635
Formal Charge	0
Total Atoms	51
Total Chiral Atoms	7
Total Bonds	54
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8X9S_Chain_A E K A E K I E K Q L Q K D K Q V Y R A T H R L L L L G A S G K S T I V K Q S G I F E T K F Q V D K V N F H M F D V G Q R D E R R K W I Q C F N D V T A I I F V V N R L Q E A L N F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C V D T E N R R F N D C R D I I Q R M H L R Q Y E L L L S A D A V R S M D N A D S S D Y D S A I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8X9S_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8X9S_Chain_G N T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q6QNK2
Sequence	>8X9S_Chain_R V V P L E L A R G H Q V A L S S I S Y V G C S L S V L C L V A T L V T F A V L S S V S T I R N Q R Y H I H A N L S F A V L V A Q V L L L I S F R L E P G T T P C Q V M A V L L H Y F F L S A F A W M L V E G L H L Y S M V I K V F G S E D S K H R Y Y Y G M G W G F P L L I C I I S L S F A M D S Y G T S N N C W L S L A S G A I W A F V A P A L F V I V V N I G I L I A V T R V I S Q I S A D N S A F K L T A K A V A V L L P I L G T S W V F G V L A V N G C A V V F Q Y M F A T L N S L Q G L F I F L F H C L L N S E V R A A F K H K T K V W S L T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7WU2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/β1/γ1	2.8	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU2 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		2.8	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7EPT	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/β1/γ2	3	2022-05-11	doi.org/10.1038/s41586-022-04619-y
	7EPT (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		3	2022-05-11	doi.org/10.1038/s41586-022-04619-y
	8X9S	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	3.49	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9S (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		3.49	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9T	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	AP503	-	chim(NtGi1-Gs)/β1/γ2	2.75	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9T (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	AP503	-		2.75	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9U	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	Metenolone	-	chim(NtGi1-Gs)/β1/γ2	2.88	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9U (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	Metenolone	-		2.88	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV1	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV1 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		2.98	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	3.53	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV2 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		3.53	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9V0U	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	chim(NtGi1-G13)/β1/γ2	3.51	2025-07-30	doi.org/10.1016/j.bbrc.2025.152165
	9V0U (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		3.51	2025-07-30	doi.org/10.1016/j.bbrc.2025.152165

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