psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:L619	5.57	Yes	No	0	0	9
2	L:L:?1	R:R:H640	5.18	Yes	Yes	0	0	9
3	L:L:?1	R:R:F643	10.79	Yes	Yes	2	0	8
4	L:L:?1	R:R:W705	32.1	Yes	No	0	0	9
5	L:L:?1	R:R:L706	5.57	Yes	No	0	0	9
6	L:L:?1	R:R:L708	10.03	Yes	No	0	0	7
7	L:L:?1	R:R:F716	22.56	Yes	Yes	2	0	9
8	R:R:L566	R:R:Y789	16.41	No	No	0	9	9
9	R:R:L620	R:R:Y571	7.03	No	No	0	8	7
10	R:R:C574	R:R:Q616	4.58	Yes	No	0	8	8
11	R:R:C574	R:R:L620	4.76	Yes	No	0	8	8
12	R:R:Q616	R:R:S577	11.55	No	No	0	8	9
13	R:R:L613	R:R:V578	4.47	No	No	0	8	7
14	R:R:V578	R:R:V617	4.81	No	No	0	7	5
15	R:R:C580	R:R:F803	5.59	No	Yes	0	7	9
16	R:R:L581	R:R:V612	5.96	Yes	No	0	9	8
17	R:R:L581	R:R:L613	8.3	Yes	No	0	9	8
18	R:R:G799	R:R:L581	5.13	No	Yes	0	8	9
19	R:R:I802	R:R:L581	4.28	No	Yes	0	8	9
20	R:R:L613	R:R:V582	4.47	No	No	0	8	4
21	R:R:A583	R:R:F803	4.16	No	Yes	0	6	9
22	R:R:F588	R:R:T584	3.89	Yes	No	1	7	9
23	R:R:F803	R:R:T584	6.49	Yes	No	1	9	9
24	R:R:C807	R:R:T584	10.14	Yes	No	1	8	9
25	R:R:F610	R:R:L585	6.09	No	No	0	4	7
26	R:R:C807	R:R:T587	5.07	Yes	No	0	8	8
27	R:R:F588	R:R:Y602	6.19	Yes	Yes	1	7	8
28	R:R:C807	R:R:F588	4.19	Yes	Yes	1	8	7
29	R:R:A816	R:R:L591	4.73	No	No	0	8	8
30	R:R:F817	R:R:L591	6.09	No	No	0	7	8
31	R:R:R598	R:R:S592	3.95	No	No	0	7	8
32	R:R:K820	R:R:S593	4.59	No	No	0	8	8
33	R:R:A816	R:R:V594	5.09	No	No	0	8	8
34	R:R:E812	R:R:T596	4.23	Yes	No	0	8	9
35	R:R:I597	R:R:Y602	16.92	No	Yes	0	8	8
36	R:R:H603	R:R:R598	5.64	No	No	0	8	7
37	R:R:N599	R:R:R601	13.26	No	Yes	1	8	8
38	R:R:N599	R:R:Y602	6.98	No	Yes	1	8	8
39	R:R:H656	R:R:Q600	6.18	Yes	No	0	8	8
40	R:R:H672	R:R:Q600	12.36	No	No	0	7	8
41	R:R:R601	R:R:Y602	8.23	Yes	Yes	1	8	8
42	R:R:H605	R:R:R601	4.51	No	Yes	0	9	8
43	R:R:E812	R:R:R601	11.63	Yes	Yes	1	8	8
44	R:R:N810	R:R:Y602	9.3	No	Yes	1	9	8
45	R:R:E812	R:R:Y602	14.59	Yes	Yes	1	8	8
46	R:R:V813	R:R:Y602	5.05	No	Yes	1	9	8
47	R:R:H603	R:R:H672	8.36	No	No	0	8	7
48	R:R:H603	R:R:Y676	6.53	No	No	0	8	8
49	R:R:I604	R:R:W649	5.87	Yes	Yes	3	9	9
50	R:R:I604	R:R:V652	6.14	Yes	No	3	9	8
51	R:R:E653	R:R:I604	6.83	No	Yes	0	9	9
52	R:R:H656	R:R:I604	5.3	Yes	Yes	0	8	9
53	R:R:E653	R:R:H605	12.31	No	No	0	9	9
54	R:R:H605	R:R:H806	11.94	No	No	0	9	9
55	R:R:N607	R:R:W649	16.95	No	Yes	0	9	9
56	R:R:N607	R:R:Y676	12.79	No	No	0	9	8
57	R:R:L608	R:R:W649	4.56	No	Yes	0	9	9
58	R:R:I802	R:R:S609	4.64	No	No	0	8	8
59	R:R:Q616	R:R:V612	4.3	No	No	0	8	8
60	R:R:Q798	R:R:V612	5.73	No	No	0	9	8
61	R:R:F642	R:R:V614	7.87	No	No	0	8	6
62	R:R:A615	R:R:F643	6.93	No	Yes	0	9	8
63	R:R:L618	R:R:L639	4.15	No	No	0	7	9
64	R:R:M635	R:R:S622	12.27	No	No	0	6	8
65	R:R:E626	R:R:P627	6.29	No	No	0	2	5
66	R:R:E626	R:R:T629	4.23	No	No	0	2	8
67	R:R:P631	R:R:T629	12.24	No	No	0	6	8
68	R:R:C632	R:R:C704	7.28	No	No	0	9	9
69	R:R:Q633	R:R:Y698	4.51	No	Yes	0	5	9
70	R:R:G699	R:R:Q633	4.93	No	No	0	8	5
71	R:R:C704	R:R:M635	4.86	No	No	0	9	6
72	R:R:A636	R:R:Y698	4	No	Yes	0	9	9
73	R:R:L691	R:R:V637	5.96	No	No	0	4	4
74	R:R:V637	R:R:Y698	20.19	No	Yes	0	4	9
75	R:R:H640	R:R:L644	3.86	Yes	No	0	9	9
76	R:R:C687	R:R:H640	4.42	No	Yes	0	8	9
77	R:R:H640	R:R:Y698	10.89	Yes	Yes	0	9	9
78	R:R:A715	R:R:H640	5.85	No	Yes	0	9	9
79	R:R:F642	R:R:Y641	8.25	No	Yes	0	8	7
80	R:R:W680	R:R:Y641	8.68	Yes	Yes	0	8	7
81	R:R:L684	R:R:Y641	11.72	No	Yes	0	5	7
82	R:R:C687	R:R:Y641	4.03	No	Yes	0	8	7
83	R:R:F643	R:R:F716	8.57	Yes	Yes	2	8	9
84	R:R:I686	R:R:L644	5.71	No	No	0	7	9
85	R:R:L644	R:R:P719	4.93	No	No	0	9	9
86	R:R:S645	R:R:W680	8.65	No	Yes	0	8	8
87	R:R:F647	R:R:M650	4.98	Yes	No	0	9	9
88	R:R:F647	R:R:F716	10.72	Yes	Yes	2	9	9
89	R:R:A720	R:R:F647	5.55	No	Yes	0	9	9
90	R:R:F647	R:R:W773	18.04	Yes	Yes	2	9	9
91	R:R:V652	R:R:W649	7.36	No	Yes	3	8	9
92	R:R:G679	R:R:W649	12.67	No	Yes	0	9	9
93	R:R:W649	R:R:W680	14.99	Yes	Yes	0	9	8
94	R:R:G770	R:R:M650	5.24	No	No	0	9	9
95	R:R:M650	R:R:Q798	4.08	No	No	0	9	9
96	R:R:L651	R:R:L655	5.54	No	No	0	9	7
97	R:R:L651	R:R:M678	5.65	No	No	0	9	7
98	R:R:L651	R:R:V726	4.47	No	No	0	9	8
99	R:R:V652	R:R:Y675	6.31	No	No	0	8	8
100	R:R:E653	R:R:I768	13.66	No	No	0	9	8
101	R:R:H656	R:R:M660	9.19	Yes	No	0	8	8
102	R:R:H656	R:R:Y675	11.98	Yes	No	0	8	8
103	R:R:L657	R:R:V734	5.96	No	No	0	9	9
104	R:R:L657	R:R:L765	5.54	No	No	0	9	9
105	R:R:I662	R:R:Y658	12.09	No	No	0	8	8
106	R:R:K663	R:R:Y658	7.17	No	No	0	7	8
107	R:R:K663	R:R:S659	6.12	No	No	0	7	8
108	R:R:M660	R:R:S667	6.13	No	No	0	8	8
109	R:R:V661	R:R:V734	6.41	No	No	0	9	9
110	R:R:V661	R:R:V737	4.81	No	No	0	9	8
111	R:R:E668	R:R:S667	5.75	No	No	0	8	8
112	R:R:H672	R:R:S670	4.18	No	No	0	7	7
113	R:R:F682	R:R:M678	7.46	No	No	0	4	7
114	R:R:F682	R:R:P683	4.33	No	No	0	4	8
115	R:R:F682	R:R:I686	7.54	No	No	0	4	7
116	R:R:S690	R:R:Y698	5.09	No	Yes	0	8	9
117	R:R:L706	R:R:Y698	19.93	No	Yes	0	9	9
118	R:R:N702	R:R:N703	12.26	No	No	0	3	7
119	R:R:N703	R:R:W705	25.99	No	No	0	7	9
120	R:R:S707	R:R:S710	4.89	No	No	5	8	4
121	R:R:I713	R:R:L708	7.14	No	No	0	8	7
122	R:R:I713	R:R:W714	7.05	No	No	0	8	8
123	R:R:I713	R:R:V717	9.22	No	No	0	8	8
124	R:R:F716	R:R:W773	6.01	Yes	Yes	2	9	9
125	R:R:F722	R:R:V726	14.42	No	No	0	5	8
126	R:R:L769	R:R:N727	5.49	Yes	No	0	9	9
127	R:R:L731	R:R:L765	4.15	Yes	No	4	8	9
128	R:R:L731	R:R:L769	4.15	Yes	Yes	4	8	9
129	R:R:L731	R:R:T771	4.42	Yes	No	0	8	8
130	R:R:T735	R:R:T758	6.28	No	No	0	9	8
131	R:R:K760	R:R:L757	4.23	No	No	0	9	8
132	R:R:K760	R:R:V764	4.55	No	No	0	9	8
133	R:R:F805	R:R:V764	3.93	No	No	0	8	8
134	R:R:L765	R:R:L769	8.3	No	Yes	4	9	9
135	R:R:L766	R:R:T771	4.42	No	No	0	8	8
136	R:R:I768	R:R:L769	4.28	No	Yes	0	8	9
137	R:R:H806	R:R:I768	15.91	No	No	0	9	8
138	R:R:N795	R:R:S772	5.96	No	No	0	9	9
139	R:R:F791	R:R:W773	6.01	No	Yes	2	9	9
140	R:R:N795	R:R:W773	27.12	No	Yes	2	9	9
141	R:R:F775	R:R:V774	5.24	No	No	0	8	5
142	R:R:F775	R:R:F787	8.57	No	No	0	8	7
143	R:R:F775	R:R:M790	4.98	No	No	0	8	5
144	R:R:F791	R:R:G776	4.52	No	No	0	9	9
145	R:R:F787	R:R:L778	28.01	No	No	0	7	7
146	R:R:A779	R:R:F787	4.16	No	No	0	8	7
147	R:R:A784	R:R:Q788	4.55	No	No	0	6	8
148	R:R:F791	R:R:N795	9.67	No	No	2	9	9
149	R:R:L797	R:R:L800	9.69	No	No	6	7	6
150	R:R:F801	R:R:L797	4.87	No	No	0	8	7
151	R:R:C807	R:R:F803	6.98	Yes	Yes	1	8	9
152	R:R:F803	R:R:L808	10.96	Yes	No	0	9	7
153	R:R:L808	R:R:L809	4.15	No	No	0	7	8
154	R:R:E812	R:R:N810	5.26	Yes	No	1	8	9
155	R:R:N810	R:R:V813	4.43	No	No	1	9	9
156	R:R:F817	R:R:T821	3.89	No	No	0	7	8
157	R:R:H819	R:R:V823	4.15	No	No	0	8	7
158	R:R:K820	R:R:W824	5.8	No	No	0	8	7
159	R:R:K822	R:R:L826	8.46	No	No	0	8	8
160	R:R:A648	R:R:P683	3.74	No	No	0	7	8
161	R:R:A718	R:R:P719	3.74	No	No	0	7	9
162	R:R:G573	R:R:S796	3.71	No	No	0	9	9
163	R:R:G711	R:R:S710	3.71	No	No	0	7	4
164	R:R:V590	R:R:W824	3.68	No	No	0	4	7
165	R:R:F643	R:R:L639	3.65	Yes	No	0	8	9
166	R:R:G654	R:R:I730	3.53	No	No	0	9	8
167	R:R:P631	R:R:T630	3.5	No	No	0	6	3
168	R:R:G681	R:R:L684	3.42	No	No	0	9	5
169	R:R:A712	R:R:S697	3.42	No	Yes	0	7	7
170	R:R:C704	R:R:T700	3.38	No	No	0	9	4
171	R:R:D669	R:R:G666	3.35	No	No	0	6	7
172	R:R:L766	R:R:P767	3.28	No	No	0	8	9
173	R:R:S697	R:R:S707	3.26	Yes	No	5	7	8
174	R:R:S697	R:R:S710	3.26	Yes	No	5	7	4
175	R:R:A816	R:R:I597	3.25	No	No	0	8	8
176	R:R:A733	R:R:I662	3.25	No	No	0	8	8
177	R:R:F801	R:R:F805	3.22	No	No	0	8	8
178	R:R:C580	R:R:L800	3.17	No	No	0	7	6
179	R:R:C632	R:R:L625	3.17	No	No	0	9	4
180	R:R:A712	R:R:L706	3.15	No	No	0	7	9
181	R:R:I621	R:R:S622	3.1	No	No	0	4	8
182	R:R:I662	R:R:V661	3.07	No	No	0	8	9
183	R:R:I724	R:R:V774	3.07	No	No	0	9	5
184	R:R:I738	R:R:V734	3.07	No	No	0	9	9
185	R:R:I741	R:R:V737	3.07	No	No	0	8	8
186	R:R:K820	R:R:V594	3.04	No	No	0	8	8
187	R:R:I728	R:R:T771	3.04	No	No	0	5	8
188	R:R:L731	R:R:T735	2.95	Yes	No	0	8	9
189	R:R:L794	R:R:T793	2.95	No	No	0	6	5
190	R:R:I688	R:R:I689	2.94	No	No	0	4	6
191	R:R:D696	R:R:S697	2.94	No	Yes	0	3	7
192	R:R:N703	R:R:T700	2.92	No	No	0	7	4
193	R:R:I730	R:R:L657	2.85	No	No	0	8	9
194	R:R:I724	R:R:L721	2.85	No	No	0	9	7
195	R:R:L691	R:R:M695	2.83	No	No	0	4	2
196	R:R:K756	R:R:L757	2.82	No	No	0	6	8
197	R:R:L576	R:R:L797	2.77	No	No	6	5	7
198	R:R:L576	R:R:L800	2.77	No	No	6	5	6
199	R:R:L618	R:R:L638	2.77	No	No	0	7	7
200	R:R:L804	R:R:L809	2.77	No	No	0	8	8
201	R:R:F722	R:R:V723	2.62	No	No	0	5	8
202	R:R:A611	R:R:W680	2.59	No	Yes	0	8	8
203	R:R:I732	R:R:R736	2.51	No	No	0	4	7
204	R:R:I724	R:R:W773	2.35	No	Yes	0	9	9
205	R:R:Q740	R:R:R736	2.34	No	No	0	8	7
206	R:R:F610	R:R:W680	2	No	Yes	0	4	8
207	R:R:A611	R:R:A646	1.79	No	No	0	8	7
208	R:R:G729	R:R:I728	1.76	No	No	0	5	5
209	R:R:G729	R:R:I732	1.76	No	No	0	5	4
210	R:R:P627	R:R:T700	1.75	No	No	0	5	4
211	R:R:C574	R:R:S570	1.72	Yes	No	0	8	7
212	R:R:C574	R:R:S796	1.72	Yes	No	0	8	9
213	R:R:A694	R:R:S697	1.71	No	Yes	0	6	7
214	R:R:G782	R:R:N781	1.7	No	No	0	3	7
215	R:R:A792	R:R:I569	1.62	No	No	0	8	9
216	R:R:S575	R:R:V572	1.62	No	No	0	7	5
217	R:R:A761	R:R:I738	1.62	No	No	0	9	9
218	R:R:V586	R:R:V590	1.6	No	No	0	6	4
219	R:R:S595	R:R:T596	1.6	No	No	0	9	9
220	R:R:S739	R:R:T758	1.6	No	No	0	8	8
221	R:R:V785	R:R:V786	1.6	No	No	0	5	5
222	R:R:T735	R:R:V762	1.59	No	No	0	9	8
223	R:R:T827	R:R:V823	1.59	No	No	0	8	7
224	R:R:I569	R:R:S570	1.55	No	No	0	9	7
225	R:R:K671	R:R:S659	1.53	No	No	0	8	8
226	R:R:K822	R:R:S825	1.53	No	No	0	8	8
227	R:R:A779	R:R:Q788	1.52	No	No	0	8	8
228	R:R:L620	R:R:S575	1.5	No	No	0	8	7
229	R:R:L794	R:R:S772	1.5	No	No	0	6	9
230	R:R:K818	R:R:T821	1.5	No	No	0	8	8
231	R:R:L579	R:R:V578	1.49	No	No	0	4	7
232	R:R:L721	R:R:V777	1.49	No	No	0	7	7
233	R:R:N781	R:R:V780	1.48	No	No	0	7	7
234	R:R:I569	R:R:L566	1.43	No	No	0	9	9
235	R:R:I689	R:R:L685	1.43	No	No	0	6	5
236	R:R:A606	R:R:F588	1.39	No	Yes	0	7	7
237	R:R:A694	R:R:F693	1.39	No	No	0	6	5
238	R:R:A763	R:R:F805	1.39	No	No	0	7	8
239	R:R:F623	R:R:S567	1.32	No	No	0	6	7
240	R:R:F665	R:R:V664	1.31	No	No	0	8	9
241	R:R:L809	R:R:R814	1.21	No	No	0	8	9
242	R:R:T827	R:R:W824	1.21	No	No	0	8	7
243	R:R:R673	R:R:Y674	1.03	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	13.1143	7	2	0
2	R:R:C574	3.195	4	0	8
3	R:R:L581	5.9175	4	0	9
4	R:R:F588	3.915	4	1	7
5	R:R:R601	9.4075	4	1	8
6	R:R:Y602	9.60857	7	1	8
7	R:R:I604	6.035	4	3	9
8	R:R:H640	6.04	5	0	9
9	R:R:Y641	8.17	4	0	7
10	R:R:F643	7.485	4	2	8
11	R:R:F647	9.8225	4	2	9
12	R:R:W649	10.4	6	3	9
13	R:R:H656	8.1625	4	0	8
14	R:R:W680	7.382	5	0	8
15	R:R:S697	2.918	5	5	7
16	R:R:Y698	10.7683	6	0	9
17	R:R:F716	11.965	4	2	9
18	R:R:L731	3.9175	4	4	8
19	R:R:L769	5.555	4	4	9
20	R:R:W773	11.906	5	2	9
21	R:R:F803	6.836	5	1	9
22	R:R:C807	6.595	4	1	8
23	R:R:E812	8.9275	4	1	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F716	60.5583	22.56	Yes	Yes	2	0	9
2	R:R:F647	R:R:F716	38.2675	10.72	Yes	Yes	2	9	9
3	R:R:F647	R:R:M650	39.2807	4.98	Yes	No	0	9	9
4	R:R:M650	R:R:Q798	36.6906	4.08	No	No	0	9	9
5	R:R:Q798	R:R:V612	35.3754	5.73	No	No	0	9	8
6	R:R:Q616	R:R:V612	21.4856	4.3	No	No	0	8	8
7	R:R:C574	R:R:Q616	18.5466	4.58	Yes	No	0	8	8
8	R:R:L581	R:R:V612	14.2455	5.96	Yes	No	0	9	8
9	L:L:?1	R:R:H640	83.6543	5.18	Yes	Yes	0	0	9
10	R:R:C687	R:R:H640	99.5169	4.42	No	Yes	0	8	9
11	R:R:C687	R:R:Y641	99.6175	4.03	No	Yes	0	8	7
12	R:R:W680	R:R:Y641	99.9195	8.68	Yes	Yes	0	8	7
13	R:R:W649	R:R:W680	100	14.99	Yes	Yes	0	9	8
14	R:R:I604	R:R:W649	95.3432	5.87	Yes	Yes	3	9	9
15	R:R:E653	R:R:I604	97.6112	6.83	No	Yes	0	9	9
16	R:R:E653	R:R:H605	78.0178	12.31	No	No	0	9	9
17	R:R:H605	R:R:R601	89.8007	4.51	No	Yes	0	9	8
18	R:R:R601	R:R:Y602	81.6748	8.23	Yes	Yes	1	8	8
19	R:R:F588	R:R:Y602	61.8533	6.19	Yes	Yes	1	7	8
20	R:R:F588	R:R:T584	28.7526	3.89	Yes	No	1	7	9
21	R:R:F803	R:R:T584	27.2495	6.49	Yes	No	1	9	9
22	R:R:C580	R:R:F803	35.5365	5.59	No	Yes	0	7	9
23	R:R:C807	R:R:F588	30.363	4.19	Yes	Yes	1	8	7
24	R:R:C807	R:R:F803	27.3636	6.98	Yes	Yes	1	8	9
25	R:R:I597	R:R:Y602	26.0619	16.92	No	Yes	0	8	8
26	R:R:A816	R:R:I597	24.3911	3.25	No	No	0	8	8
27	R:R:A816	R:R:V594	15.8357	5.09	No	No	0	8	8
28	R:R:K820	R:R:V594	14.071	3.04	No	No	0	8	8
29	R:R:H656	R:R:I604	13.3195	5.3	Yes	Yes	0	8	9
30	R:R:H605	R:R:H806	14.8091	11.94	No	No	0	9	9
31	R:R:E653	R:R:I768	45.8968	13.66	No	No	0	9	8
32	R:R:H806	R:R:I768	14.5407	15.91	No	No	0	9	8
33	L:L:?1	R:R:W705	22.8947	32.1	Yes	No	0	0	9
34	R:R:N703	R:R:W705	21.4453	25.99	No	No	0	7	9
35	R:R:N703	R:R:T700	18.5063	2.92	No	No	0	7	4
36	R:R:H640	R:R:Y698	20.2912	10.89	Yes	Yes	0	9	9
37	L:L:?1	R:R:L706	17.171	5.57	Yes	No	0	0	9
38	R:R:L706	R:R:Y698	13.1853	19.93	No	Yes	0	9	9
39	R:R:H640	R:R:L644	20.2241	3.86	Yes	No	0	9	9
40	R:R:I686	R:R:L644	15.829	5.71	No	No	0	7	9
41	R:R:F682	R:R:I686	14.3058	7.54	No	No	0	4	7
42	R:R:I768	R:R:L769	56.7671	4.28	No	Yes	0	8	9
43	R:R:L765	R:R:L769	29.4035	8.3	No	Yes	4	9	9
44	R:R:L657	R:R:L765	28.813	5.54	No	No	0	9	9
45	R:R:L657	R:R:V734	23.4449	5.96	No	No	0	9	9
46	R:R:V661	R:R:V734	17.983	6.41	No	No	0	9	9
47	R:R:I662	R:R:V661	12.0311	3.07	No	No	0	8	9
48	R:R:A712	R:R:L706	20.1235	3.15	No	No	0	7	9
49	R:R:A712	R:R:S697	17.6542	3.42	No	Yes	0	7	7
50	R:R:L731	R:R:L769	23.9683	4.15	Yes	Yes	4	8	9
51	R:R:L731	R:R:T771	16.2115	4.42	Yes	No	0	8	8
52	R:R:C580	R:R:L800	32.3089	3.17	No	No	0	7	6
53	R:R:L797	R:R:L800	25.7599	9.69	No	No	6	7	6
54	R:R:F801	R:R:L797	22.5458	4.87	No	No	0	8	7
55	R:R:F801	R:R:F805	19.2646	3.22	No	No	0	8	8
56	R:R:F805	R:R:V764	13.0712	3.93	No	No	0	8	8
57	R:R:K760	R:R:V764	10.0382	4.55	No	No	0	9	8
58	R:R:F716	R:R:W773	22.9685	6.01	Yes	Yes	2	9	9
59	R:R:I724	R:R:W773	16.594	2.35	No	Yes	0	9	9
60	R:R:I724	R:R:V774	12.2727	3.07	No	No	0	9	5
61	R:R:F775	R:R:V774	10.7294	5.24	No	No	0	8	5
62	R:R:F803	R:R:L808	13.3597	10.96	Yes	No	0	9	7
63	R:R:L808	R:R:L809	10.0382	4.15	No	No	0	7	8
64	R:R:K820	R:R:W824	10.7428	5.8	No	No	0	8	7
65	R:R:I728	R:R:T771	10.2597	3.04	No	No	0	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:L619	5.57	2	Yes	No	0	9	0	1
L:L:?1	R:R:H640	5.18	2	Yes	Yes	0	9	0	1
L:L:?1	R:R:F643	10.79	2	Yes	Yes	0	8	0	1
L:L:?1	R:R:W705	32.1	2	Yes	No	0	9	0	1
L:L:?1	R:R:L706	5.57	2	Yes	No	0	9	0	1
L:L:?1	R:R:L708	10.03	2	Yes	No	0	7	0	1
L:L:?1	R:R:F716	22.56	2	Yes	Yes	0	9	0	1
R:R:A615	R:R:F643	6.93	0	No	Yes	9	8	2	1
R:R:H640	R:R:L644	3.86	0	Yes	No	9	9	1	2
R:R:C687	R:R:H640	4.42	0	No	Yes	8	9	2	1
R:R:H640	R:R:Y698	10.89	0	Yes	Yes	9	9	1	2
R:R:A715	R:R:H640	5.85	0	No	Yes	9	9	2	1
R:R:F643	R:R:F716	8.57	2	Yes	Yes	8	9	1	1
R:R:F647	R:R:F716	10.72	2	Yes	Yes	9	9	2	1
R:R:F647	R:R:W773	18.04	2	Yes	Yes	9	9	2	2
R:R:L706	R:R:Y698	19.93	0	No	Yes	9	9	1	2
R:R:N703	R:R:W705	25.99	0	No	No	7	9	2	1
R:R:I713	R:R:L708	7.14	0	No	No	8	7	2	1
R:R:F716	R:R:W773	6.01	2	Yes	Yes	9	9	1	2
R:R:F643	R:R:L639	3.65	2	Yes	No	8	9	1	2
R:R:A712	R:R:L706	3.15	0	No	No	7	9	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9IV1_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.86
Number of Linked Nodes	235
Number of Links	243
Number of Hubs	23
Number of Links mediated by Hubs	88
Number of Communities	6
Number of Nodes involved in Communities	29
Number of Links involved in Communities	36

Path Summary
Number Of Nodes in MetaPath	66
Number Of Links MetaPath	65
Number of Shortest Paths	30683
Length Of Smallest Path	3
Average Path Length	14.3799
Length of Longest Path	34
Minimum Path Strength	1.4
Average Path Strength	7.48981
Maximum Path Strength	29.045
Minimum Path Correlation	0.7
Average Path Correlation	0.917255
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	44.4299
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.1724
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	DHT
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	DHT
Name	Stanolone
Synonyms	Androstanolona
Identifier
Formula	C19 H30 O2
Molecular Weight	290.44
SMILES
PubChem	10635
Formal Charge	0
Total Atoms	51
Total Chiral Atoms	7
Total Bonds	54
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q6QNK2
Sequence	>9IV1_nogp_Chain_R Q V A L S S I S Y V G C S L S V L C L V A T L V T F A V L S S V S T I R N Q R Y H I H A N L S F A V L V A Q V L L L I S F R L E P G T T P C Q V M A V L L H Y F F L S A F A W M L V E G L H L Y S M V I K V F G S E D S K H R Y Y Y G M G W G F P L L I C I I S L S F A M D S Y G T S N N C W L S L A S G A I W A F V A P A L F V I V V N I G I L I A V T R V I S Q I S A A F K L T A K A V A V L L P I L G T S W V F G V L A V N G C A V V F Q Y M F A T L N S L Q G L F I F L F H C L L N S E V R A A F K H K T K V W S L T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9IV2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	3.53	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV2 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		3.53	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV1	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV1 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		2.98	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9U	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	Metenolone	-	chim(NtGi1-Gs)/β1/γ2	2.88	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9U (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	Metenolone	-		2.88	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9T	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	AP503	-	chim(NtGi1-Gs)/β1/γ2	2.75	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9T (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	AP503	-		2.75	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9S	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	3.49	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9S (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		3.49	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	7EPT	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/β1/γ2	3	2022-05-11	10.1038/s41586-022-04619-y
	7EPT (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		3	2022-05-11	10.1038/s41586-022-04619-y
	7WU2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/β1/γ1	2.8	2022-04-27	10.1038/s41586-022-04580-w
	7WU2 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		2.8	2022-04-27	10.1038/s41586-022-04580-w

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9IV1_nogp.zip

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