Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1A:A:I34 6.1125409
2A:A:Y44 6.51754192
3A:A:K50 4.425409
4A:A:L52 6.21419
5A:A:L53 4.8525479
6A:A:L54 9.8419
7A:A:N58 6.0685119
8A:A:I206 3.94419
9A:A:Y209 5.11407
10A:A:P217 3.45254194
11A:A:F218 6.2585167
12A:A:M220 4.98408
13A:A:V223 4.5475419
14A:A:R227 9.475419
15A:A:R230 12.516519
16A:A:R232 9.07833619
17A:A:W233 7619
18A:A:F234 6.4075419
19A:A:E235 5.8925418
20A:A:F237 4.65333619
21A:A:S242 4.3225408
22A:A:I243 5.28418
23A:A:L244 4.0575478
24A:A:V247 5.2475407
25A:A:D248 9.29254118
26A:A:D251 7.384118
27A:A:F252 4.0725409
28A:A:V276 6.2325406
29A:A:V280 6.1175415
30A:A:F281 4.8475419
31A:A:I287 4.6075479
32A:A:F289 4.63779
33A:A:L290 6409
34A:A:I305 5.484176
35A:A:F309 6.1856179
36A:A:F325 7.4545176
37A:A:Y343 10.0275409
38A:A:F346 10.4154215
39A:A:N351 5.572579
40A:A:D361 10.2825407
41A:A:L367 3.5775407
42A:A:N370 6.118538
43B:B:L30 8.844235
44B:B:R49 12.056527
45B:B:H54 7.9629
46B:B:Y59 10.0675418
47B:B:W63 9.8975407
48B:B:S72 4.1725429
49B:B:S74 4.805429
50B:B:D76 7.014529
51B:B:W82 10.2867629
52B:B:D83 9.195428
53B:B:S84 8.7575425
54B:B:Y85 9.444524
55B:B:K89 6.57529
56B:B:I93 7.7654107
57B:B:W99 6.09619
58B:B:Y111 7.06754244
59B:B:L117 5.13619
60B:B:S122 5.49754108
61B:B:I123 4.215406
62B:B:Y124 6.4045106
63B:B:V133 6.38754104
64B:B:E138 6.334106
65B:B:H142 5.72333619
66B:B:Y145 8.788518
67B:B:L146 5.4575417
68B:B:C149 3.045408
69B:B:L152 3.8925403
70B:B:T159 4.835419
71B:B:S161 6.7175419
72B:B:G162 4.11419
73B:B:D163 5.65833619
74B:B:W169 10.496518
75B:B:D170 5.83754259
76B:B:F180 5.7525467
77B:B:H183 9.648569
78B:B:M188 8.8075418
79B:B:L190 5.4425465
80B:B:F199 6.1025469
81B:B:V200 6.205456
82B:B:K209 10.27466
83B:B:W211 7.2425468
84B:B:E215 6.995403
85B:B:H225 11.155659
86B:B:I229 5.655457
87B:B:F234 7.57455
88B:B:F235 7.72875886
89B:B:N239 6.3525402
90B:B:F241 6.162556
91B:B:T243 6.7325458
92B:B:D247 7.948559
93B:B:T249 5.1975456
94B:B:R251 7.73658
95B:B:F253 8.418556
96B:B:Q259 4.325186
97B:B:L261 6.235405
98B:B:H266 8.8025494
99B:B:C271 3.5425405
100B:B:I273 5.7925406
101B:B:F278 5.775487
102B:B:R283 7.9925129
103B:B:L285 5.2425486
104B:B:Y289 5.606597
105B:B:N295 4.74496
106B:B:V296 5.39405
107B:B:W297 8.4625498
108B:B:D298 9.49254129
109B:B:L300 6.9265126
110B:B:H311 10.24254139
111B:B:N313 6.3175417
112B:B:R314 8.8418
113B:B:M325 6.27525
114B:B:W332 10.2567619
115B:B:F335 5.7525404
116B:B:K337 9.31254136
117B:B:W339 8.6085139
118B:B:N340 6.7975429
119G:G:R27 8.4154228
120G:G:V30 3.56754188
121G:G:Y40 10.315486
122G:G:D48 6.9225409
123G:G:N59 7.172529
124G:G:F61 5.69333628
125R:R:F547 7.375649
126R:R:A548 3.4449
127R:R:M551 3.86509
128R:R:H562 11.86254277
129R:R:L581 4.246676149
130R:R:T584 5.3054149
131R:R:L591 4.7225408
132R:R:I597 2.735408
133R:R:I604 6.546539
134R:R:L613 2.475408
135R:R:Q616 6.172548
136R:R:Y641 6.9425407
137R:R:F643 5.778548
138R:R:F647 8.51549
139R:R:W649 9.05857739
140R:R:L651 4.3125409
141R:R:V652 6.975438
142R:R:H656 8.094538
143R:R:L657 4.3725409
144R:R:M660 6.26438
145R:R:F665 6.1954168
146R:R:Y675 9.035438
147R:R:W680 7.718538
148R:R:P683 3.1525408
149R:R:W705 9.648549
150R:R:I713 4.945648
151R:R:W714 6.5525448
152R:R:F716 5.065409
153R:R:L731 4.35408
154R:R:W773 8.4225849
155R:R:F775 6.84754158
156R:R:Q788 5.8325408
157R:R:F791 5.5125449
158R:R:N795 10.9275449
159R:R:L797 4.13754287
160R:R:F803 6.193336149
161R:R:H806 7.24439
162R:R:E812 5.964298
163R:R:K820 4.5025408
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1A:A:I34 A:A:R30 14.111712.53YesNo095
2A:A:R30 B:B:H91 13.23965.64NoNo055
3A:A:I34 B:B:K89 15.41735.82YesYes099
4A:A:E41 A:A:V45 26.93727.13NoNo053
5A:A:V45 B:B:L55 26.81052.98NoNo036
6B:B:D76 B:B:L55 26.62986.79YesNo096
7B:B:D76 B:B:H54 26.16635.04YesYes299
8B:B:H54 B:B:W82 18.03427.41YesYes299
9B:B:K89 B:B:W82 12.19058.12YesYes299
10A:A:E41 A:A:Y44 27.123711.22NoYes052
11A:A:P217 A:A:Y44 26.65585.56YesYes1942
12A:A:K50 A:A:L48 72.19014.23YesNo096
13A:A:F218 A:A:V216 97.6493.93YesNo074
14A:A:P217 A:A:V216 97.98943.53YesNo044
15A:A:K219 A:A:K50 69.5414.31NoYes069
16A:A:F218 A:A:I51 95.22023.77YesNo077
17A:A:I51 A:A:S242 93.49036.19NoYes078
18B:B:C317 B:B:M61 17.75316.48NoNo076
19B:B:C317 B:B:S316 17.75193.44NoNo079
20B:B:S316 B:B:W332 17.99514.94NoYes099
21A:A:E235 B:B:W332 26.72034.36YesYes189
22A:A:F234 A:A:V280 11.47333.93YesYes195
23A:A:F234 A:A:F281 11.23766.43YesYes199
24B:B:W332 B:B:Y59 16.310612.54YesYes198
25B:B:Q75 B:B:Y59 16.838113.53NoYes098
26B:B:Q75 B:B:W99 16.9375.48NoYes099
27A:A:V221 B:B:W99 68.00344.9NoYes069
28A:A:F281 A:A:I243 13.02745.02YesYes198
29A:A:N58 A:A:S59 11.48412.98YesNo099
30A:A:L246 A:A:S59 11.72813NoNo079
31A:A:F289 A:A:L246 10.29264.87YesNo797
32A:A:I287 A:A:S242 48.48494.64YesYes098
33B:B:L117 B:B:W99 58.98494.56YesYes199
34A:A:E235 A:A:K231 22.48256.75YesNo187
35A:A:K231 A:A:R232 29.10874.95NoYes179
36A:A:R230 A:A:R232 46.658519.19YesYes199
37A:A:R230 B:B:Y145 49.083717.49YesYes198
38B:B:L117 B:B:Y145 62.56123.52YesYes198
39A:A:R232 B:B:D228 27.96963.57YesNo099
40A:A:R232 B:B:D246 27.90793.57YesNo199
41A:A:S242 A:A:S285 45.0473.26YesNo088
42A:A:I243 A:A:I286 13.44195.89YesNo087
43A:A:I286 A:A:V276 12.74074.61NoYes076
44A:A:S285 A:A:T365 44.94729.59NoNo086
45A:A:T365 A:A:Y343 44.87933.75NoYes069
46A:A:D361 A:A:I287 51.57735.6YesYes079
47A:A:D361 A:A:Y343 56.986522.99YesYes079
48A:A:D364 A:A:Y343 1009.2NoYes089
49A:A:D364 A:A:L367 99.22332.71NoYes087
50A:A:L367 R:R:V664 49.46374.47YesNo079
51A:A:I366 R:R:V664 48.86183.07NoNo089
52A:A:I366 A:A:N370 48.60675.66NoYes088
53A:A:L367 R:R:V661 49.14522.98YesNo079
54A:A:N370 R:R:M660 40.69735.61YesYes388
55B:B:D228 B:B:S227 27.77124.42NoNo096
56B:B:S227 B:B:S245 55.06893.26NoNo069
57B:B:H225 B:B:S245 36.470613.95YesNo599
58B:B:H225 B:B:T243 18.00929.58YesYes598
59B:B:F253 B:B:T243 14.74165.19YesYes568
60B:B:F222 B:B:F253 35.297420.36NoYes586
61B:B:F222 B:B:Q220 34.020423.42NoNo087
62B:B:D258 B:B:Q220 33.210316.97NoNo077
63B:B:D258 G:G:I25 23.72499.8NoNo2272
64G:G:E22 G:G:I25 22.56384.1NoNo092
65G:G:E22 G:G:Q18 21.379214.02NoNo099
66G:G:L19 G:G:Q18 20.19437.99NoNo099
67B:B:A11 G:G:L19 15.45131.58NoNo059
68B:B:A11 G:G:V16 11.89051.7NoNo057
69B:B:D246 B:B:S227 27.73085.89NoNo096
70B:B:H225 B:B:R251 15.994221.44YesYes598
71B:B:F253 B:B:R251 29.30094.28YesYes568
72B:B:D247 B:B:S245 18.17628.83YesNo599
73B:B:D247 B:B:R251 15.95634.76YesYes598
74B:B:D290 B:B:R314 24.350613.1NoYes068
75B:B:C271 B:B:D290 23.82853.11YesNo056
76B:B:C271 B:B:Y289 20.65354.03YesYes057
77B:B:W297 B:B:Y289 17.19843.86YesYes987
78B:B:W297 B:B:Y264 16.805210.61YesNo085
79B:B:R314 B:B:W332 24.312611YesYes189
80B:B:L51 B:B:W82 13.143322.78NoYes299
81B:B:L51 B:B:R49 12.617415.79NoYes297
82B:B:R49 B:B:S84 12.25414.5YesYes275
83B:B:S84 G:G:F61 20.48316.61YesYes258
84B:B:M325 G:G:F61 14.13943.73YesYes258
85B:B:M325 G:G:P49 14.04285.03YesNo057
86G:G:D48 G:G:P49 12.00394.83YesNo097
87B:B:A328 B:B:M61 10.45313.22NoNo056
88B:B:M188 B:B:S147 11.05253.07YesNo089
89B:B:S147 B:B:S160 10.81854.89NoNo096
90B:B:A328 B:B:W63 10.19035.19NoYes057
91B:B:G162 B:B:Y145 24.11544.35YesYes198
92B:B:G162 B:B:S161 17.03533.71YesYes199
93B:B:H142 B:B:W169 13.5366.35YesYes198
94B:B:L139 B:B:W169 10.90829.61NoYes098
95B:B:I123 B:B:L139 15.30042.85YesNo069
96B:B:D163 B:B:G162 12.21783.35YesYes199
97B:B:H91 B:B:V133 10.15788.3NoYes054
98R:R:V661 R:R:V734 46.38013.21NoNo099
99R:R:L657 R:R:V734 46.08665.96YesNo099
100R:R:G654 R:R:L657 44.38321.71NoYes099
101R:R:G654 R:R:L769 44.10041.71NoNo099
102R:R:L769 R:R:N727 40.130512.36NoNo099
103R:R:N727 R:R:V723 39.85872.96NoNo098
104R:R:F647 R:R:V723 39.16266.55YesNo098
105R:R:F647 R:R:W773 17.792621.05YesYes499
106R:R:F647 R:R:F716 18.90874.29YesYes099
107R:R:F643 R:R:F716 10.01363.22YesYes089
108R:R:H656 R:R:M660 40.30797.88YesYes388
109R:R:H656 R:R:I604 34.92165.3YesYes389
110R:R:I604 R:R:W649 29.77197.05YesYes399
111R:R:L608 R:R:W649 21.76664.56NoYes099
112R:R:L608 R:R:V612 21.45932.98NoNo098
113R:R:Q616 R:R:V612 11.9914.3YesNo088
114R:R:F547 R:R:L619 23.62293.65YesNo099
115R:R:L581 R:R:V612 10.68572.98YesNo098
116R:R:L619 R:R:L639 17.7354.15NoNo099
117R:R:L639 R:R:S622 14.78663NoNo098
118A:A:K219 A:A:V221 69.49733.04NoNo066
119A:A:L48 A:A:P217 71.37073.28NoYes1964
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9V0U
Class B2
SubFamily Adhesion
Type Adhesion
SubType ADGRD1
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners chim(NtGi1-G13)/Beta1/Gamma2
PDB Resolution 3.51
Date 2025-07-30
D.O.I. doi.org/10.1016/j.bbrc.2025.152165
Net Summary
Imin 2.98
Number of Linked Nodes 823
Number of Links 992
Number of Hubs 163
Number of Links mediated by Hubs 580
Number of Communities 29
Number of Nodes involved in Communities 237
Number of Links involved in Communities 334
Path Summary
Number Of Nodes in MetaPath 120
Number Of Links MetaPath 119
Number of Shortest Paths 1092146
Length Of Smallest Path 3
Average Path Length 28.5117
Length of Longest Path 59
Minimum Path Strength 1.265
Average Path Strength 6.60145
Maximum Path Strength 21.89
Minimum Path Correlation 0.7
Average Path Correlation 0.976163
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.38095
Average % Of Corr. Nodes 43.5819
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 50.1872
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • cell surface receptor signaling pathway   • multicellular organismal process   • system process   • nervous system process   • neuromuscular process   • regulation of system process   • skeletal muscle contraction   • muscle contraction   • muscle system process   • regulation of muscle system process   • striated muscle contraction   • multicellular organismal movement   • musculoskeletal movement   • regulation of striated muscle contraction   • regulation of muscle contraction   • regulation of skeletal muscle contraction   • regulation of multicellular organismal process   • cellular anatomical structure   • membrane   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • intracellular organelle lumen   • nuclear speck   • ribonucleoprotein granule   • intracellular organelle   • nuclear body   • nucleoplasm
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • intracellular organelle lumen   • nuclear speck   • ribonucleoprotein granule   • intracellular organelle   • nuclear body   • nucleoplasm   • organelle lumen   • organelle   • membraneless organelle   • supramolecular complex   • nuclear ribonucleoprotein granule   • nuclear lumen   • cytoplasm   • cytosol   • cell periphery   • plasma membrane   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • organelle membrane   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • signaling receptor binding   • G protein-coupled receptor binding   • D5 dopamine receptor binding   • dopamine receptor binding   • GTPase regulator activity   • enzyme regulator activity   • guanyl-nucleotide exchange factor activity   • nucleoside-triphosphatase regulator activity   • molecular function regulator activity   • G-protein beta/gamma-subunit complex binding   • G protein activity   • cation binding   • metal ion binding   • circulatory system process   • regulation of blood pressure   • regulation of biological quality   • blood circulation   • cellular developmental process   • cell differentiation   • regulation of cell motility   • regulation of fibroblast migration   • fibroblast migration   • regulation of locomotion   • ameboidal-type cell migration   • regulation of cell migration   • cell migration   • cell motility   • locomotion   • embryo development ending in birth or egg hatching   • chordate embryonic development   • embryo development   • in utero embryonic development   • regulation of developmental process   • regulation of cell shape   • cell morphogenesis   • regulation of cell morphogenesis   • anatomical structure morphogenesis   • regulation of anatomical structure morphogenesis   • regulation of body fluid levels   • wound healing   • cell activation   • hemostasis   • blood coagulation   • response to stress   • coagulation   • response to wounding   • platelet activation   • branching morphogenesis of an epithelial tube   • angiogenesis   • tube morphogenesis   • epithelial tube morphogenesis   • blood vessel development   • epithelium development   • blood vessel morphogenesis   • tube development   • morphogenesis of an epithelium   • tissue development   • vasculature development   • circulatory system development   • branching involved in blood vessel morphogenesis   • tissue morphogenesis   • morphogenesis of a branching structure   • anatomical structure formation involved in morphogenesis   • morphogenesis of a branching epithelium   • regulation of cellular component organization   • cellular component organization   • cellular component biogenesis   • cellular component assembly   • regulation of postsynapse assembly   • cell junction assembly   • regulation of synapse structure or activity   • synapse organization   • cellular component organization or biogenesis   • regulation of synapse assembly   • postsynapse organization   • postsynapse assembly   • regulation of postsynapse organization   • nervous system development   • regulation of cellular component biogenesis   • regulation of cell junction assembly   • regulation of synapse organization   • cell junction organization   • synapse assembly   • Rho-activating G protein-coupled receptor signaling pathway   • regulation of signaling   • regulation of small GTPase mediated signal transduction   • regulation of signal transduction   • regulation of intracellular signal transduction   • regulation of response to stimulus   • regulation of cell communication   • Rho protein signal transduction   • anchoring junction   • focal adhesion   • cell-substrate junction   • pigment granule   • intracellular vesicle   • melanosome   • cytoplasmic vesicle   • brush border membrane   • cluster of actin-based cell projections   • brush border   • apical part of cell   • plasma membrane region   • apical plasma membrane   • cell projection membrane   • postsynapse
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainA
ProteinG Protein α Sub unit
UniProtQ14344
Sequence
>9V0U_Chain_A
SKEIDKCLS REKTYVKRL VKILLLGAS GKSTFLKQM RIGIHEYDF 
EIKNVPFKM VDVGGQRSE RKRWFECFD SVTSILFLV SSFNRLTES 
LNFETIVNN RVFSNVSII LFLNKTDLL EEKVQIVSI KDYFLEFDP 
HCLRDVQKF LVECFRNKR RDQQKPLYH HFTTAINTE NRLFRDVKD 
TILHDNLKQ LMDKAAAER DNDDDAI


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainB
ProteinG Protein β Sub unit
UniProtP62873
Sequence
>9V0U_Chain_B
LDQLRQEAE QLKNQIRDA RKACADATL SQITNNIDP VGRIQMRTR 
RTLRGHLAK IYAMHWGTD SRLLVSASQ DGKLIIWDS YTTNKVHAI 
PLRSSWVMT CAYAPSGNY VACGGLDNI CSIYNLKTN VRVSRELAG 
HTGYLSCCR FLDDNQIVT SSGDTTCAL WDIETGQQT TTFTGHTGD 
VMSLSLAPD TRLFVSGAC DASAKLWDV REGMCRQTF TGHESDINA 
ICFFPNGNA FATGSDDAT CRLFDLRAD QELMTYSHD NIICGITSV 
SFSKSGRLL LAGYDDFNC NVWDALKAD RAGVLAGHD NRVSCLGVT 
DDGMAVATG SWDSFLKIW N


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainG
ProteinG Protein γ Sub unit
UniProtP59768
Sequence
>9V0U_Chain_G
SIAQARKLV EQLKMEANI DRIKVSKAA ADLMAYCEA HAKEDPLLT 
PVPASENPF R


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ6QNK2
Sequence
>9V0U_Chain_R
NFAILMQVV PLELARGHQ VALSSISYV GCSLSVLCL VATLVTFAV 
LSSVSTIRN QRYHIHANL SFAVLVAQV LLLISFRLE PGTTPCQVM 
AVLLHYFFL SAFAWMLVE GLHLYSMVI KVFGSEDSK HRYYYGMGW 
GFPLLICII SLSFAMDSY GTSNNCWLS LASGAIWAF VAPALFVIV 
VNIGILIAV TRVISQISA DNFKLTAKA VAVLLPILG TSWVFGVLA 
VAVVFQYMF ATLNSLQGL FIFLFHCLL NSEVRAAFK HKTKVWSLT


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7WU2B2AdhesionAdhesionADGRD1Homo sapiens--Gs/β1/γ12.82022-04-27doi.org/10.1038/s41586-022-04580-w
7WU2 (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiens--2.82022-04-27doi.org/10.1038/s41586-022-04580-w
7EPTB2AdhesionAdhesionADGRD1Homo sapiens--Gs/β1/γ232022-05-11doi.org/10.1038/s41586-022-04619-y
7EPT (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiens--32022-05-11doi.org/10.1038/s41586-022-04619-y
8X9SB2AdhesionAdhesionADGRD1Homo sapiens5α-DHT-chim(NtGi1-Gs)/β1/γ23.492025-02-12doi.org/10.1016/j.cell.2025.01.006
8X9S (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiens5α-DHT-3.492025-02-12doi.org/10.1016/j.cell.2025.01.006
8X9TB2AdhesionAdhesionADGRD1Homo sapiensAP503-chim(NtGi1-Gs)/β1/γ22.752025-02-12doi.org/10.1016/j.cell.2025.01.006
8X9T (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiensAP503-2.752025-02-12doi.org/10.1016/j.cell.2025.01.006
8X9UB2AdhesionAdhesionADGRD1Homo sapiensMetenolone-chim(NtGi1-Gs)/β1/γ22.882025-02-12doi.org/10.1016/j.cell.2025.01.006
8X9U (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiensMetenolone-2.882025-02-12doi.org/10.1016/j.cell.2025.01.006
9IV1B2AdhesionAdhesionADGRD1Homo sapiens5α-DHT-chim(NtGi1-Gs)/β1/γ22.982025-02-12doi.org/10.1016/j.cell.2025.01.006
9IV1 (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiens5α-DHT-2.982025-02-12doi.org/10.1016/j.cell.2025.01.006
9IV2B2AdhesionAdhesionADGRD1Homo sapiens5α-DHT-chim(NtGi1-Gs)/β1/γ23.532025-02-12doi.org/10.1016/j.cell.2025.01.006
9IV2 (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiens5α-DHT-3.532025-02-12doi.org/10.1016/j.cell.2025.01.006
9V0UB2AdhesionAdhesionADGRD1Homo sapiens--chim(NtGi1-G13)/β1/γ23.512025-07-30doi.org/10.1016/j.bbrc.2025.152165
9V0U (No Gprot) B2AdhesionAdhesionADGRD1Homo sapiens--3.512025-07-30doi.org/10.1016/j.bbrc.2025.152165




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