psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:C46	L:L:K41	9.7	No	No	3	0	0
2	L:L:K41	L:L:K48	7.18	No	No	0	0	0
3	L:L:C52	L:L:K41	3.23	Yes	No	3	0	0
4	L:L:C43	L:L:C52	7.28	No	Yes	3	0	0
5	L:L:C43	L:L:C55	3.64	No	Yes	3	0	0
6	L:L:C43	L:L:C74	7.28	No	Yes	3	0	0
7	L:L:L44	L:L:Q56	5.32	No	No	0	0	0
8	E:E:L131	L:L:S45	6.01	No	No	0	9	0
9	L:L:C46	L:L:C52	7.28	No	Yes	3	0	0
10	L:L:D49	L:L:S47	2.94	Yes	No	3	0	0
11	L:L:N50	L:L:S47	2.98	Yes	No	3	0	0
12	E:E:E127	L:L:S47	5.75	No	No	3	9	0
13	L:L:D49	L:L:N50	2.69	Yes	Yes	3	0	0
14	E:E:K125	L:L:D49	12.44	Yes	Yes	3	9	0
15	E:E:M192	L:L:D49	5.54	Yes	Yes	3	9	0
16	E:E:H102	L:L:N50	12.75	Yes	Yes	3	9	0
17	E:E:P103	L:L:N50	6.52	No	Yes	3	9	0
18	E:E:K125	L:L:N50	5.6	Yes	Yes	3	9	0
19	E:E:E127	L:L:N50	6.57	No	Yes	3	9	0
20	L:L:G51	L:L:Y71	4.35	No	No	0	0	0
21	L:L:C52	L:L:E73	3.04	Yes	No	0	0	0
22	E:E:E127	L:L:S53	7.19	No	No	0	9	0
23	L:L:C55	L:L:Q56	3.05	Yes	No	0	0	0
24	L:L:C55	L:L:F61	2.79	Yes	Yes	3	0	0
25	L:L:C55	L:L:C74	7.28	Yes	Yes	3	0	0
26	L:L:L59	L:L:Q56	5.32	No	No	0	0	0
27	L:L:K58	R:R:N114	4.2	Yes	No	0	0	9
28	L:L:K58	R:R:H140	7.86	Yes	No	0	0	8
29	L:L:K58	R:R:D162	4.15	Yes	No	0	0	9
30	L:L:C74	L:L:L59	7.94	Yes	No	0	0	0
31	L:L:H76	L:L:L59	6.43	No	No	0	0	0
32	L:L:F60	L:L:G84	4.52	Yes	No	0	0	0
33	L:L:F60	L:L:R86	8.55	Yes	Yes	1	0	0
34	L:L:F60	L:L:N91	3.62	Yes	No	1	0	0
35	L:L:C93	L:L:F60	2.79	Yes	Yes	1	0	0
36	L:L:F61	L:L:L63	6.09	Yes	Yes	3	0	0
37	L:L:F61	L:L:M90	8.71	Yes	No	3	0	0
38	L:L:F61	L:L:R92	4.28	Yes	No	0	0	0
39	E:E:L104	L:L:F61	4.87	No	Yes	3	9	0
40	L:L:F62	L:L:R64	10.69	Yes	No	0	0	0
41	L:L:F62	L:L:P79	4.33	Yes	Yes	1	0	0
42	L:L:F62	L:L:Y82	14.44	Yes	Yes	1	0	0
43	L:L:C93	L:L:F62	2.79	Yes	Yes	1	0	0
44	L:L:L63	L:L:Q70	9.32	Yes	No	3	0	0
45	E:E:H102	L:L:L63	6.43	Yes	Yes	3	9	0
46	L:L:Q70	L:L:R65	14.02	No	No	0	0	0
47	E:E:Y116	L:L:R65	13.38	Yes	No	0	9	0
48	L:L:E66	L:L:R69	4.65	No	No	50	0	0
49	L:L:E66	L:L:Y71	11.22	No	No	50	0	0
50	E:E:I98	L:L:M68	7.29	No	No	3	8	0
51	E:E:V195	L:L:M68	3.04	Yes	No	3	9	0
52	E:E:A201	L:L:M68	3.22	No	No	0	9	0
53	L:L:R69	L:L:Y71	9.26	No	No	50	0	0
54	E:E:N196	L:L:R69	3.62	No	No	0	9	0
55	E:E:H102	L:L:Q70	3.71	Yes	No	3	9	0
56	L:L:E73	L:L:L75	3.98	No	No	0	0	0
57	L:L:L75	L:L:P79	3.28	No	Yes	0	0	0
58	L:L:H76	R:R:G90	3.18	No	No	0	0	9
59	L:L:S77	R:R:R135	3.95	No	Yes	0	0	9
60	L:L:C78	L:L:Y82	2.69	No	Yes	1	0	0
61	L:L:C78	L:L:C93	7.28	No	Yes	1	0	0
62	L:L:P79	L:L:Y82	6.95	Yes	Yes	1	0	0
63	L:L:C93	L:L:Y82	4.03	Yes	Yes	1	0	0
64	L:L:R95	L:L:Y82	15.43	No	Yes	0	0	0
65	L:L:A94	L:L:Y83	6.67	No	No	0	0	0
66	L:L:C104	L:L:Y83	4.03	No	No	0	0	0
67	L:L:K107	L:L:Y83	5.97	No	No	0	0	0
68	L:L:N91	L:L:R86	3.62	No	Yes	1	0	0
69	L:L:R86	R:R:D137	10.72	Yes	Yes	1	0	9
70	L:L:R86	R:R:A138	4.15	Yes	No	1	0	9
71	L:L:R86	R:R:D161	10.72	Yes	Yes	1	0	9
72	L:L:P88	R:R:L186	3.28	No	No	1	0	9
73	L:L:P88	R:R:N210	11.4	No	Yes	1	0	9
74	L:L:D89	L:L:M90	2.77	No	No	0	0	0
75	E:E:L104	L:L:M90	2.83	No	No	3	9	0
76	E:E:N110	L:L:R92	3.62	No	No	0	9	0
77	L:L:R95	L:L:R97	5.33	No	No	0	0	0
78	L:L:C104	L:L:C96	3.64	No	No	0	0	0
79	E:E:E112	L:L:R97	13.96	No	No	0	9	0
80	L:L:E99	L:L:I98	5.47	No	Yes	0	0	0
81	L:L:C101	L:L:I98	4.91	No	Yes	22	0	0
82	L:L:C110	L:L:I98	3.27	Yes	Yes	22	0	0
83	L:L:I98	L:L:R123	2.51	Yes	Yes	0	0	0
84	L:L:E99	L:L:N100	7.89	No	Yes	0	0	0
85	L:L:K114	L:L:N100	4.2	Yes	Yes	22	0	0
86	L:L:F117	L:L:N100	15.71	No	Yes	22	0	0
87	L:L:C124	L:L:N100	3.15	No	Yes	22	0	0
88	L:L:C101	L:L:C110	7.28	No	Yes	22	0	0
89	L:L:D102	L:L:K112	5.53	No	No	0	0	0
90	L:L:D102	L:L:K114	6.91	No	Yes	0	0	0
91	L:L:K112	L:L:S103	3.06	No	No	0	0	0
92	L:L:F105	L:L:S106	7.93	Yes	No	0	0	0
93	L:L:F105	L:L:F109	6.43	Yes	Yes	1	0	0
94	L:L:F105	R:R:W159	14.03	Yes	Yes	1	0	9
95	L:L:F105	R:R:A181	8.32	Yes	No	0	0	9
96	L:L:F105	R:R:T183	3.89	Yes	Yes	1	0	9
97	L:L:F105	R:R:V205	3.93	Yes	Yes	1	0	9
98	L:L:S106	R:R:H207	5.58	No	Yes	0	0	9
99	L:L:D108	L:L:R123	10.72	No	Yes	0	0	0
100	L:L:F109	L:L:G122	6.02	Yes	No	0	0	0
101	L:L:F109	R:R:H157	5.66	Yes	Yes	0	0	9
102	L:L:F109	R:R:Q180	3.51	Yes	Yes	1	0	9
103	L:L:F109	R:R:V204	6.55	Yes	Yes	1	0	9
104	L:L:F109	R:R:V205	5.24	Yes	Yes	1	0	9
105	L:L:C110	L:L:C113	5.46	Yes	No	22	0	0
106	L:L:C110	L:L:C124	3.64	Yes	No	22	0	0
107	L:L:T111	R:R:H157	6.85	No	Yes	0	0	9
108	L:L:C113	L:L:L119	7.94	No	No	0	0	0
109	L:L:C113	L:L:C124	7.28	No	No	22	0	0
110	L:L:G116	L:L:K114	3.49	No	Yes	0	0	0
111	L:L:F117	L:L:K114	6.2	No	Yes	22	0	0
112	L:L:D126	L:L:F117	3.58	No	No	0	0	0
113	L:L:C128	L:L:Y118	5.38	No	No	27	0	0
114	L:L:M139	L:L:Y118	4.79	No	No	0	0	0
115	L:L:C141	L:L:Y118	4.03	Yes	No	27	0	0
116	L:L:H120	L:L:R121	12.41	Yes	No	0	0	0
117	L:L:H120	L:L:P129	4.58	Yes	Yes	27	0	0
118	L:L:F132	L:L:H120	14.71	No	Yes	27	0	0
119	L:L:C141	L:L:H120	5.9	Yes	Yes	27	0	0
120	L:L:R121	R:R:V204	2.62	No	Yes	0	0	9
121	L:L:R121	R:R:N226	8.44	No	No	0	0	8
122	L:L:F125	L:L:R123	6.41	No	Yes	0	0	0
123	L:L:R123	R:R:K251	4.95	Yes	Yes	0	0	9
124	L:L:E127	L:L:P129	7.86	No	Yes	0	0	0
125	L:L:C128	L:L:P129	3.77	No	Yes	27	0	0
126	L:L:C128	L:L:C141	7.28	No	Yes	27	0	0
127	L:L:F132	L:L:P129	5.78	No	Yes	27	0	0
128	L:L:C141	L:L:P129	3.77	Yes	Yes	27	0	0
129	L:L:F132	L:L:G131	3.01	No	No	0	0	0
130	L:L:A133	L:L:D136	4.63	No	No	51	0	0
131	L:L:A133	L:L:E140	4.53	No	No	51	0	0
132	L:L:E137	L:L:L135	10.6	No	No	0	0	0
133	L:L:D136	L:L:E140	12.99	No	No	51	0	0
134	L:L:E140	L:L:T138	2.82	No	No	0	0	0
135	M:M:G42	M:M:K41	3.49	No	No	0	0	0
136	M:M:C46	M:M:K41	6.47	No	No	52	0	0
137	M:M:C52	M:M:K41	4.85	No	No	52	0	0
138	M:M:C43	M:M:C52	5.46	No	No	0	0	0
139	M:M:C43	M:M:C74	3.64	No	No	0	0	0
140	M:M:L44	M:M:R54	7.29	No	No	0	0	0
141	M:M:L44	M:M:Q56	2.66	No	No	0	0	0
142	M:M:R54	M:M:S45	3.95	No	No	4	0	0
143	M:M:S45	T:T:L131	7.51	No	Yes	4	0	9
144	M:M:C46	M:M:C52	7.28	No	No	52	0	0
145	M:M:N50	M:M:S47	4.47	Yes	No	4	0	0
146	M:M:S47	T:T:E127	8.62	No	Yes	4	0	9
147	M:M:D49	T:T:K125	9.68	No	Yes	4	0	9
148	M:M:D49	T:T:M192	6.93	No	Yes	4	0	9
149	M:M:N50	T:T:Q100	3.96	Yes	No	0	0	7
150	M:M:N50	T:T:H102	10.2	Yes	Yes	4	0	9
151	M:M:N50	T:T:P103	6.52	Yes	No	4	0	9
152	M:M:N50	T:T:K125	6.99	Yes	Yes	4	0	9
153	M:M:N50	T:T:E127	6.57	Yes	Yes	4	0	9
154	M:M:S53	T:T:H102	5.58	No	Yes	4	0	9
155	M:M:S53	T:T:L104	3	No	Yes	4	0	9
156	M:M:R54	T:T:L131	7.29	No	Yes	4	0	9
157	M:M:C55	M:M:L59	3.17	No	Yes	4	0	0
158	M:M:C55	M:M:F61	4.19	No	Yes	4	0	0
159	M:M:C55	M:M:C74	7.28	No	No	4	0	0
160	M:M:L59	M:M:Q56	2.66	Yes	No	0	0	0
161	M:M:K58	M:M:Q57	23.05	Yes	No	0	0	0
162	M:M:K58	S:S:N114	2.8	Yes	Yes	6	0	9
163	M:M:K58	S:S:A138	3.21	Yes	No	6	0	9
164	M:M:K58	S:S:H140	2.62	Yes	No	0	0	8
165	M:M:K58	S:S:D162	15.21	Yes	No	6	0	9
166	M:M:C74	M:M:L59	4.76	No	Yes	4	0	0
167	M:M:H76	M:M:L59	3.86	No	Yes	0	0	0
168	M:M:F60	M:M:G84	4.52	No	No	0	0	0
169	M:M:F60	M:M:R86	12.83	No	Yes	0	0	0
170	M:M:F60	M:M:N91	3.62	No	No	0	0	0
171	M:M:F61	M:M:L63	6.09	Yes	Yes	0	0	0
172	M:M:F61	M:M:G72	3.01	Yes	No	0	0	0
173	M:M:F61	M:M:M90	9.95	Yes	No	4	0	0
174	M:M:F61	M:M:R92	4.28	Yes	No	0	0	0
175	M:M:F61	T:T:L104	6.09	Yes	Yes	4	0	9
176	M:M:F62	M:M:R64	9.62	Yes	No	12	0	0
177	M:M:F62	M:M:P79	4.33	Yes	No	12	0	0
178	M:M:F62	M:M:Y82	13.41	Yes	Yes	12	0	0
179	M:M:C93	M:M:F62	4.19	No	Yes	12	0	0
180	M:M:L63	M:M:Q70	7.99	Yes	No	0	0	0
181	M:M:L63	T:T:H102	5.14	Yes	Yes	0	0	9
182	M:M:R64	M:M:Y71	8.23	No	Yes	12	0	0
183	M:M:E73	M:M:R64	13.96	No	No	12	0	0
184	M:M:Q70	M:M:R65	16.35	No	No	0	0	0
185	M:M:R65	T:T:V99	3.92	No	Yes	7	0	7
186	M:M:R65	T:T:Y116	10.29	No	Yes	7	0	9
187	M:M:E66	M:M:R69	4.65	No	No	12	0	0
188	M:M:E66	M:M:Y71	10.1	No	Yes	12	0	0
189	M:M:M68	T:T:I98	2.92	No	No	53	0	8
190	M:M:M68	T:T:V195	4.56	No	No	0	0	9
191	M:M:M68	T:T:A201	3.22	No	No	53	0	9
192	M:M:R69	M:M:Y71	7.2	No	Yes	12	0	0
193	M:M:R69	T:T:N196	3.62	No	No	0	0	9
194	M:M:E73	M:M:Y71	8.98	No	Yes	12	0	0
195	M:M:L75	M:M:P79	4.93	No	No	0	0	0
196	M:M:H76	S:S:G90	3.18	No	No	0	0	9
197	M:M:H76	S:S:Q113	3.71	No	Yes	0	0	9
198	M:M:S77	S:S:Q113	4.33	No	Yes	0	0	9
199	M:M:C78	M:M:Y82	2.69	No	Yes	12	0	0
200	M:M:C78	M:M:C93	7.28	No	No	12	0	0
201	M:M:P79	M:M:Y82	5.56	No	Yes	12	0	0
202	M:M:C93	M:M:Y82	4.03	No	Yes	12	0	0
203	M:M:R95	M:M:Y82	16.46	No	Yes	0	0	0
204	M:M:A94	M:M:Y83	5.34	No	No	0	0	0
205	M:M:C104	M:M:Y83	4.03	No	No	0	0	0
206	M:M:K107	M:M:Y83	5.97	No	No	0	0	0
207	M:M:H85	S:S:H209	3.58	No	Yes	0	0	9
208	M:M:R86	S:S:Q113	3.5	Yes	Yes	6	0	9
209	M:M:R86	S:S:D137	5.96	Yes	Yes	6	0	9
210	M:M:R86	S:S:A138	2.77	Yes	No	6	0	9
211	M:M:R86	S:S:D161	10.72	Yes	No	6	0	9
212	M:M:R86	S:S:D162	3.57	Yes	No	6	0	9
213	M:M:R86	S:S:L186	3.64	Yes	Yes	6	0	9
214	M:M:P88	S:S:N210	9.77	No	Yes	0	0	9
215	M:M:D89	T:T:K134	6.91	No	No	0	0	9
216	M:M:M90	T:T:L104	2.83	No	Yes	4	0	9
217	M:M:R95	M:M:R97	5.33	No	No	0	0	0
218	M:M:C104	M:M:C96	5.46	No	No	0	0	0
219	M:M:R97	T:T:E112	6.98	No	No	0	0	9
220	M:M:C101	M:M:I98	3.27	No	No	17	0	0
221	M:M:C110	M:M:I98	3.27	Yes	No	17	0	0
222	M:M:I98	M:M:R123	2.51	No	No	0	0	0
223	M:M:E99	M:M:N100	13.15	No	Yes	0	0	0
224	M:M:K114	M:M:N100	4.2	Yes	Yes	17	0	0
225	M:M:F117	M:M:N100	13.29	Yes	Yes	17	0	0
226	M:M:C101	M:M:C110	7.28	No	Yes	17	0	0
227	M:M:D102	M:M:K112	5.53	No	No	0	0	0
228	M:M:D102	M:M:K114	2.77	No	Yes	0	0	0
229	M:M:F105	M:M:S106	3.96	Yes	No	6	0	0
230	M:M:F105	M:M:F109	5.36	Yes	Yes	6	0	0
231	M:M:F105	S:S:W159	13.03	Yes	Yes	6	0	9
232	M:M:F105	S:S:A181	8.32	Yes	No	6	0	9
233	M:M:F105	S:S:T183	5.19	Yes	No	0	0	9
234	M:M:F105	S:S:V205	2.62	Yes	Yes	6	0	9
235	M:M:S106	S:S:V205	3.23	No	Yes	6	0	9
236	M:M:S106	S:S:H207	4.18	No	Yes	6	0	9
237	M:M:D108	M:M:K107	4.15	No	No	0	0	0
238	M:M:K107	T:T:D111	4.15	No	No	0	0	9
239	M:M:D108	S:S:T229	5.78	No	No	0	0	9
240	M:M:D108	S:S:E252	5.2	No	No	0	0	9
241	M:M:F109	M:M:G122	6.02	Yes	No	0	0	0
242	M:M:F109	S:S:H157	4.53	Yes	Yes	6	0	9
243	M:M:F109	S:S:Q180	3.51	Yes	No	0	0	9
244	M:M:F109	S:S:A181	2.77	Yes	No	6	0	9
245	M:M:F109	S:S:V204	6.55	Yes	Yes	6	0	9
246	M:M:F109	S:S:V205	6.55	Yes	Yes	6	0	9
247	M:M:C110	M:M:C113	5.46	Yes	No	17	0	0
248	M:M:C110	M:M:C124	3.64	Yes	No	17	0	0
249	M:M:T111	S:S:H157	10.95	No	Yes	0	0	9
250	M:M:C113	M:M:L119	6.35	No	No	0	0	0
251	M:M:C113	M:M:C124	7.28	No	No	17	0	0
252	M:M:K114	M:M:V115	3.04	Yes	No	0	0	0
253	M:M:G116	M:M:K114	3.49	No	Yes	17	0	0
254	M:M:F117	M:M:K114	6.2	Yes	Yes	17	0	0
255	M:M:F117	M:M:G116	3.01	Yes	No	17	0	0
256	M:M:D126	M:M:F117	7.17	No	Yes	0	0	0
257	M:M:L135	M:M:Y118	3.52	No	No	24	0	0
258	M:M:M139	M:M:Y118	8.38	No	No	24	0	0
259	M:M:H120	M:M:R121	10.16	Yes	No	0	0	0
260	M:M:H120	M:M:P129	4.58	Yes	Yes	24	0	0
261	M:M:F132	M:M:H120	5.66	No	Yes	0	0	0
262	M:M:C141	M:M:H120	4.42	Yes	Yes	24	0	0
263	M:M:R121	S:S:V204	3.92	No	Yes	0	0	9
264	M:M:R121	S:S:N226	10.85	No	No	0	0	8
265	M:M:F125	M:M:R123	6.41	No	No	0	0	0
266	M:M:R123	S:S:K251	4.95	No	Yes	0	0	9
267	M:M:E127	M:M:P129	6.29	No	Yes	0	0	0
268	M:M:C128	M:M:P129	3.77	No	Yes	24	0	0
269	M:M:C128	M:M:C141	7.28	No	Yes	24	0	0
270	M:M:C141	M:M:P129	3.77	Yes	Yes	24	0	0
271	M:M:F132	M:M:G131	3.01	No	No	0	0	0
272	M:M:A133	M:M:D136	6.18	No	No	0	0	0
273	M:M:L135	M:M:M139	4.24	No	No	24	0	0
274	M:M:D136	M:M:E140	5.2	No	No	0	0	0
275	E:E:K56	E:E:R87	6.19	No	No	28	8	5
276	E:E:K56	E:E:N169	2.8	No	Yes	28	8	9
277	E:E:E57	E:E:F85	7	No	Yes	41	8	8
278	E:E:E57	E:E:T91	4.23	No	No	41	8	8
279	E:E:E57	E:E:H207	6.15	No	Yes	41	8	9
280	E:E:F60	E:E:T58	5.19	Yes	Yes	18	8	8
281	E:E:T58	E:E:T82	3.14	Yes	No	18	8	8
282	E:E:R84	E:E:T58	6.47	No	Yes	0	8	8
283	E:E:P210	E:E:T58	3.5	Yes	Yes	18	9	8
284	E:E:A59	E:E:F85	8.32	No	Yes	0	9	8
285	E:E:F60	E:E:T82	3.89	Yes	No	18	8	8
286	E:E:F60	E:E:P209	10.11	Yes	Yes	18	8	7
287	E:E:F60	E:E:P210	4.33	Yes	Yes	18	8	9
288	E:E:F60	S:S:I519	6.28	Yes	Yes	18	8	4
289	E:E:L81	E:E:V61	5.96	No	No	0	8	9
290	E:E:I205	E:E:V61	3.07	No	No	0	9	9
291	E:E:E62	E:E:T78	4.23	No	No	7	9	9
292	E:E:E62	E:E:R204	4.65	No	Yes	7	9	9
293	E:E:E62	S:S:R460	12.79	No	No	7	9	9
294	E:E:I194	E:E:V63	3.07	No	No	0	9	9
295	E:E:R204	E:E:V64	7.85	Yes	No	7	9	9
296	E:E:V64	T:T:Y118	3.79	No	Yes	7	9	9
297	E:E:L65	E:E:Q198	6.65	No	No	0	9	9
298	E:E:F66	E:E:V200	3.93	No	No	0	9	9
299	E:E:F66	T:T:Y118	19.6	No	Yes	0	9	9
300	E:E:E67	E:E:T75	7.06	No	No	0	9	8
301	E:E:T75	S:S:R392	11.64	No	Yes	0	8	6
302	E:E:T76	T:T:Y118	4.99	No	Yes	0	9	9
303	E:E:T79	E:E:Y77	3.75	Yes	No	7	9	6
304	E:E:Y77	S:S:G435	2.9	No	No	0	6	4
305	E:E:Y77	S:S:N458	3.49	No	Yes	7	6	4
306	E:E:T78	S:S:N437	2.92	No	Yes	7	9	5
307	E:E:T78	S:S:R460	2.59	No	No	7	9	9
308	E:E:T79	S:S:N458	4.39	Yes	Yes	7	9	4
309	E:E:R84	E:E:Y182	9.26	No	Yes	0	8	9
310	E:E:F85	E:E:T91	10.38	Yes	No	41	8	8
311	E:E:F85	E:E:V181	2.62	Yes	No	0	8	9
312	E:E:L168	E:E:S86	7.51	Yes	No	0	9	9
313	E:E:S86	E:E:Y182	5.09	No	Yes	0	9	9
314	E:E:N169	E:E:R87	8.44	Yes	No	28	9	5
315	E:E:A88	E:E:L168	3.15	No	Yes	0	9	9
316	E:E:A88	E:E:V180	5.09	No	No	0	9	9
317	E:E:H207	E:E:T91	4.11	Yes	No	41	9	8
318	E:E:S93	T:T:S93	6.52	No	No	18	9	9
319	E:E:A94	E:E:T152	3.36	No	No	0	9	9
320	E:E:A94	E:E:I205	3.25	No	No	0	9	9
321	E:E:E95	E:E:R202	18.61	Yes	Yes	0	8	9
322	E:E:E95	E:E:R204	24.42	Yes	Yes	0	8	9
323	E:E:E95	T:T:E95	3.81	Yes	Yes	0	8	8
324	E:E:E95	T:T:T152	4.23	Yes	No	0	8	9
325	E:E:G96	E:E:R202	4.5	No	Yes	0	8	9
326	E:E:E97	E:E:V99	2.85	No	No	0	7	7
327	E:E:E117	E:E:E97	2.54	No	No	0	9	7
328	E:E:I98	E:E:V123	3.07	No	No	0	8	9
329	E:E:I98	E:E:V195	4.61	No	Yes	3	8	9
330	E:E:V99	E:E:Y116	2.52	No	Yes	0	7	9
331	E:E:V99	E:E:W120	4.9	No	Yes	0	7	9
332	E:E:Q100	E:E:V195	4.3	No	Yes	0	7	9
333	E:E:L106	E:E:M101	4.24	No	No	0	9	9
334	E:E:M101	E:E:Y116	7.18	No	Yes	0	9	9
335	E:E:M101	E:E:W120	5.82	No	Yes	0	9	9
336	E:E:H102	E:E:P103	10.68	Yes	No	3	9	9
337	E:E:H102	E:E:L104	6.43	Yes	No	3	9	9
338	E:E:K142	E:E:L106	4.23	No	No	0	7	9
339	E:E:A146	E:E:L106	3.15	No	No	0	9	9
340	E:E:C107	E:E:N109	3.15	No	No	0	9	8
341	E:E:C107	E:E:C136	5.46	No	No	0	9	9
342	E:E:N108	E:E:R145	3.62	No	Yes	0	9	9
343	E:E:N109	E:E:N110	9.54	No	No	0	8	9
344	E:E:E113	E:E:N110	7.89	No	No	0	9	9
345	E:E:D111	E:E:E112	6.5	No	No	0	9	9
346	E:E:E113	E:E:R145	8.14	No	Yes	54	9	9
347	E:E:E113	E:E:R149	11.63	No	No	54	9	9
348	E:E:E117	E:E:Y116	4.49	No	Yes	0	9	9
349	E:E:R149	E:E:Y116	3.09	No	Yes	0	9	9
350	E:E:G119	E:E:Y118	2.9	No	Yes	29	9	9
351	E:E:G150	E:E:Y118	2.9	No	Yes	0	9	9
352	E:E:Y118	T:T:V64	3.79	Yes	Yes	29	9	9
353	E:E:Y118	T:T:F66	18.57	Yes	No	0	9	9
354	E:E:Y118	T:T:T76	8.74	Yes	No	29	9	9
355	E:E:Y118	T:T:R202	3.09	Yes	Yes	29	9	9
356	E:E:Y118	T:T:R204	3.09	Yes	Yes	29	9	9
357	E:E:G119	E:E:W120	2.81	No	Yes	0	9	9
358	E:E:G119	T:T:R202	4.5	No	Yes	29	9	9
359	E:E:G122	E:E:W120	2.81	No	Yes	0	9	9
360	E:E:A151	E:E:W120	10.37	No	Yes	0	9	9
361	E:E:A153	E:E:V121	3.39	No	No	0	9	9
362	E:E:I155	E:E:V121	3.07	Yes	No	0	9	9
363	E:E:A203	E:E:V121	5.09	No	No	0	9	9
364	E:E:I155	E:E:V123	3.07	Yes	No	0	9	9
365	E:E:L126	E:E:V124	2.98	No	No	55	9	9
366	E:E:F156	E:E:V124	7.87	Yes	No	55	9	9
367	E:E:D157	E:E:K125	5.53	Yes	Yes	3	9	9
368	E:E:K125	E:E:M192	2.88	Yes	Yes	3	9	9
369	E:E:F156	E:E:L126	4.87	Yes	No	55	9	9
370	E:E:E130	E:E:Q128	16.57	No	No	0	6	9
371	E:E:E160	E:E:Q128	3.82	No	No	0	9	9
372	E:E:E130	E:E:P129	6.29	No	No	0	6	9
373	E:E:N161	E:E:P129	13.03	Yes	No	0	9	9
374	E:E:D132	E:E:P135	9.66	No	No	0	9	9
375	E:E:K134	E:E:P135	3.35	No	No	0	9	9
376	E:E:C136	E:E:L137	4.76	No	No	0	9	9
377	E:E:L140	E:E:T138	4.42	No	No	0	9	9
378	E:E:L168	E:E:V139	2.98	Yes	No	0	9	9
379	E:E:A143	E:E:F156	2.77	No	Yes	0	9	9
380	E:E:K144	E:E:Q148	5.42	No	No	0	9	9
381	E:E:Q148	E:E:R145	3.5	No	Yes	0	9	9
382	E:E:R145	E:E:R149	4.26	Yes	No	54	9	9
383	E:E:R178	E:E:V147	2.62	Yes	No	0	9	9
384	E:E:R178	E:E:T152	6.47	Yes	No	0	9	9
385	E:E:T152	T:T:E95	7.06	No	Yes	0	9	8
386	E:E:F156	E:E:V154	6.55	Yes	No	0	9	9
387	E:E:I155	E:E:V183	3.07	Yes	No	0	9	9
388	E:E:I155	E:E:L191	2.85	Yes	No	0	9	9
389	E:E:F156	E:E:V180	2.62	Yes	No	0	9	9
390	E:E:D157	E:E:S159	7.36	Yes	No	0	9	9
391	E:E:A188	E:E:D157	4.63	No	Yes	0	9	9
392	E:E:D157	E:E:M192	4.16	Yes	Yes	3	9	9
393	E:E:A164	E:E:V158	3.39	No	No	0	9	9
394	E:E:I165	E:E:V158	3.07	Yes	No	28	9	9
395	E:E:V158	E:E:Y182	5.05	No	Yes	28	9	9
396	E:E:N161	E:E:P162	3.26	Yes	No	56	9	7
397	E:E:E163	E:E:N161	6.57	No	Yes	56	8	9
398	E:E:A164	E:E:N161	4.69	No	Yes	0	9	9
399	E:E:E163	E:E:P162	6.29	No	No	56	8	7
400	E:E:I165	E:E:N169	4.25	Yes	Yes	28	9	9
401	E:E:I165	E:E:Y182	9.67	Yes	Yes	28	9	9
402	E:E:D174	E:E:P175	6.44	No	No	0	9	9
403	E:E:K177	R:R:Q438	6.78	No	Yes	0	9	9
404	E:E:P179	E:E:R178	10.09	No	Yes	0	9	9
405	E:E:R178	T:T:R204	10.66	Yes	Yes	0	9	9
406	E:E:I205	E:E:P179	3.39	No	No	0	9	9
407	E:E:K184	E:E:Y182	7.17	No	Yes	0	9	9
408	E:E:A188	E:E:V183	3.39	No	No	0	9	9
409	E:E:M192	E:E:V195	3.04	Yes	Yes	3	9	9
410	E:E:I194	E:E:Q198	5.49	No	No	0	9	9
411	E:E:K197	E:E:N196	13.99	No	No	0	9	9
412	E:E:K197	E:E:Q198	4.07	No	No	0	9	9
413	E:E:K199	E:E:V200	4.55	No	No	0	9	9
414	E:E:R202	T:T:Y118	3.09	Yes	Yes	7	9	9
415	E:E:R202	T:T:G119	6	Yes	Yes	7	9	9
416	E:E:R204	T:T:Y118	3.09	Yes	Yes	7	9	9
417	E:E:R204	T:T:R178	12.79	Yes	Yes	0	9	9
418	E:E:P209	E:E:Q206	9.47	Yes	Yes	18	7	9
419	E:E:Q206	S:S:I519	5.49	Yes	Yes	18	9	4
420	E:E:H207	E:E:R208	6.77	Yes	No	0	9	9
421	E:E:H207	T:T:R208	4.51	Yes	No	0	9	9
422	E:E:R208	E:E:R211	4.26	No	No	0	9	8
423	E:E:Q212	E:E:R208	7.01	No	No	0	8	9
424	E:E:P209	E:E:P210	7.79	Yes	Yes	18	7	9
425	E:E:P209	S:S:I519	3.39	Yes	Yes	18	7	4
426	E:E:P210	E:E:Q212	7.9	Yes	No	0	9	8
427	E:E:R211	E:E:Y216	4.12	No	Yes	0	8	9
428	E:E:P213	E:E:Y216	4.17	No	Yes	0	9	9
429	E:E:E215	E:E:T214	8.47	Yes	No	0	9	9
430	E:E:E215	E:E:Y216	11.22	Yes	Yes	9	9	9
431	E:E:E215	T:T:Q212	16.57	Yes	Yes	9	9	8
432	E:E:E215	T:T:E215	7.61	Yes	Yes	9	9	9
433	E:E:E215	T:T:D218	3.9	Yes	Yes	9	9	9
434	E:E:Y216	S:S:S778	3.82	Yes	Yes	0	9	6
435	E:E:Y216	T:T:Q212	3.38	Yes	Yes	9	9	8
436	E:E:F217	S:S:S538	5.28	No	No	0	9	9
437	E:E:D218	E:E:I221	4.2	No	No	0	9	9
438	E:E:D218	T:T:E215	2.6	No	Yes	0	9	9
439	E:E:M219	S:S:I781	7.29	No	Yes	9	9	8
440	E:E:M219	T:T:D218	9.7	No	Yes	9	9	9
441	E:E:M219	T:T:F222	4.98	No	Yes	9	9	9
442	E:E:G220	T:T:F222	4.52	No	Yes	0	9	9
443	E:E:I221	S:S:M540	2.92	No	No	0	9	5
444	E:E:F222	R:R:I781	12.56	No	Yes	0	9	8
445	E:E:F222	T:T:M219	24.88	No	Yes	0	9	9
446	E:E:L223	S:S:F789	3.65	No	Yes	0	9	7
447	E:E:L223	T:T:F222	7.31	No	Yes	0	9	9
448	E:E:A224	S:S:M540	3.22	No	No	0	9	5
449	E:E:F225	R:R:F789	3.22	No	Yes	0	9	7
450	E:E:F226	R:R:F789	3.22	No	Yes	0	9	7
451	E:E:F226	T:T:F226	21.43	No	Yes	0	9	9
452	E:E:V227	X:X:?1	4.46	No	Yes	0	9	0
453	E:E:V229	W:W:?1	2.97	No	Yes	0	9	0
454	E:E:S230	T:T:F226	2.64	No	Yes	5	9	9
455	E:E:S230	W:W:?1	2.99	No	Yes	5	9	0
456	E:E:S230	X:X:?1	13.48	No	Yes	5	9	0
457	E:E:L231	E:E:L234	2.77	No	No	0	9	9
458	E:E:L231	S:S:F547	4.87	No	No	0	9	4
459	E:E:V232	R:R:I758	3.07	No	No	0	9	7
460	E:E:L234	X:X:?1	6.9	No	Yes	0	9	0
461	E:E:I240	E:E:L236	2.85	No	No	5	9	9
462	E:E:L236	R:R:W751	6.83	No	Yes	5	9	8
463	E:E:L236	R:R:F754	3.65	No	Yes	0	9	8
464	E:E:I240	E:E:L237	7.14	No	No	0	9	9
465	E:E:K241	E:E:L237	8.46	No	No	0	9	9
466	E:E:L237	W:W:?1	4.14	No	Yes	0	9	0
467	E:E:K239	E:E:V238	3.04	No	No	0	9	8
468	E:E:I240	R:R:W751	8.22	No	Yes	5	9	8
469	E:E:K243	R:R:S743	3.06	No	No	0	9	4
470	R:R:C33	R:R:V41	3.42	No	Yes	0	9	7
471	R:R:C33	R:R:C43	7.28	No	No	0	9	8
472	R:R:C33	R:R:K46	4.85	No	No	0	9	4
473	R:R:D42	R:R:S34	4.42	No	No	0	9	4
474	R:R:C35	R:R:V41	3.42	No	Yes	0	9	7
475	R:R:D38	R:R:R40	14.29	No	Yes	0	6	3
476	R:R:F58	R:R:R39	13.9	No	No	0	6	7
477	R:R:Q60	R:R:R39	3.5	No	No	0	5	7
478	R:R:A61	R:R:R40	6.91	No	Yes	58	4	3
479	R:R:E85	R:R:R40	5.82	No	Yes	58	8	3
480	R:R:L55	R:R:V41	10.43	No	Yes	57	6	7
481	R:R:T59	R:R:V41	6.35	No	Yes	57	8	7
482	R:R:D42	R:R:S44	7.36	No	Yes	42	9	7
483	R:R:D42	R:R:D63	6.65	No	Yes	42	9	9
484	R:R:C43	R:R:P52	3.77	No	No	0	8	8
485	R:R:D63	R:R:S44	5.89	Yes	Yes	42	9	7
486	R:R:S44	R:R:S65	3.26	Yes	No	42	7	9
487	R:R:M66	R:R:S44	3.07	No	Yes	0	9	7
488	R:R:G45	R:R:M66	3.49	No	No	0	8	9
489	R:R:K46	R:R:L48	9.87	No	No	0	4	8
490	R:R:L48	R:R:N67	5.49	No	Yes	0	8	9
491	R:R:A76	R:R:V51	5.09	No	No	0	4	5
492	R:R:F77	R:R:V51	3.93	No	No	0	7	5
493	R:R:L62	R:R:P52	3.28	No	No	0	5	8
494	R:R:L55	R:R:T59	2.95	No	No	57	6	8
495	R:R:E84	R:R:Q60	16.57	No	No	0	6	5
496	R:R:A61	R:R:E85	4.53	No	No	58	4	8
497	R:R:I64	R:R:L62	5.71	No	No	0	6	5
498	R:R:F80	R:R:L62	3.65	Yes	No	0	7	5
499	R:R:D63	R:R:S65	4.42	Yes	No	42	9	9
500	R:R:D63	R:R:Q87	7.83	Yes	No	0	9	8
501	R:R:I64	R:R:N67	9.91	No	Yes	0	6	9
502	R:R:I64	R:R:L88	5.71	No	Yes	0	6	9
503	R:R:A89	R:R:S65	3.42	No	No	0	9	9
504	R:R:I69	R:R:N67	2.83	No	Yes	59	7	9
505	R:R:N67	R:R:N91	6.81	Yes	No	59	9	9
506	R:R:I69	R:R:N91	8.5	No	No	59	7	9
507	R:R:F95	R:R:Q71	3.51	No	No	0	3	4
508	R:R:L72	R:R:P73	4.93	Yes	No	0	7	5
509	R:R:F77	R:R:L72	7.31	No	Yes	0	7	7
510	R:R:I96	R:R:L72	7.14	Yes	Yes	0	9	7
511	R:R:A100	R:R:L72	3.15	No	Yes	0	8	7
512	R:R:A76	R:R:P73	5.61	No	No	0	4	5
513	R:R:D75	R:R:E74	12.99	Yes	No	38	4	5
514	R:R:E74	R:R:H97	29.54	No	Yes	38	5	8
515	R:R:E74	R:R:K99	5.4	No	Yes	38	5	3
516	R:R:D75	R:R:K99	4.15	Yes	Yes	38	4	3
517	R:R:D75	R:R:S102	2.94	Yes	No	38	4	5
518	R:R:F77	R:R:F80	3.22	No	Yes	0	7	7
519	R:R:F80	R:R:N79	10.87	Yes	No	0	7	4
520	R:R:F80	R:R:L83	3.65	Yes	No	0	7	9
521	R:R:F82	R:R:P81	5.78	No	No	0	5	5
522	R:R:L104	R:R:L83	2.77	No	No	0	9	9
523	R:R:E84	R:R:E85	13.95	No	No	0	6	8
524	R:R:E84	R:R:K108	4.05	No	No	0	6	8
525	R:R:L86	R:R:L88	4.15	No	Yes	0	8	9
526	R:R:L107	R:R:L86	2.77	No	No	8	9	8
527	R:R:L110	R:R:L86	2.77	Yes	No	8	9	8
528	R:R:Q87	R:R:T111	7.09	No	No	0	8	9
529	R:R:L88	R:R:N91	6.87	Yes	No	0	9	9
530	R:R:L88	R:R:L93	4.15	Yes	No	0	9	9
531	R:R:L112	R:R:L88	4.15	Yes	Yes	0	9	9
532	R:R:A89	R:R:Q113	6.06	No	Yes	0	9	9
533	R:R:G90	R:R:N114	5.09	No	No	0	9	9
534	R:R:D92	R:R:Q116	7.83	No	No	0	5	6
535	R:R:I96	R:R:L93	2.85	Yes	No	0	9	9
536	R:R:L93	R:R:N115	6.87	No	Yes	0	9	9
537	R:R:F95	R:R:H97	6.79	No	Yes	0	3	8
538	R:R:I96	R:R:L101	4.28	Yes	No	60	9	7
539	R:R:A124	R:R:I96	4.87	No	Yes	60	8	9
540	R:R:H97	R:R:P98	12.2	Yes	No	0	8	4
541	R:R:H97	R:R:K99	5.24	Yes	Yes	38	8	3
542	R:R:E123	R:R:P98	3.14	No	No	0	5	4
543	R:R:K99	R:R:S102	7.65	Yes	No	38	3	5
544	R:R:A124	R:R:L101	3.15	No	No	60	8	7
545	R:R:E106	R:R:K105	2.7	No	No	0	7	3
546	R:R:L107	R:R:L110	2.77	No	Yes	8	9	9
547	R:R:K108	R:R:V109	3.04	No	No	0	8	8
548	R:R:K108	R:R:Q132	13.56	No	No	0	8	8
549	R:R:S133	R:R:V109	6.46	No	No	0	9	8
550	R:R:L110	R:R:L112	5.54	Yes	Yes	0	9	9
551	R:R:L110	R:R:L131	5.54	Yes	Yes	8	9	9
552	R:R:L110	R:R:L134	4.15	Yes	Yes	8	9	9
553	R:R:Q113	R:R:T111	7.09	Yes	No	1	9	9
554	R:R:R135	R:R:T111	9.06	Yes	No	1	9	9
555	R:R:L112	R:R:N115	2.75	Yes	Yes	0	9	9
556	R:R:L112	R:R:L136	4.15	Yes	No	0	9	9
557	R:R:Q113	R:R:R135	3.5	Yes	Yes	1	9	9
558	R:R:D137	R:R:Q113	3.92	Yes	Yes	1	9	9
559	R:R:A138	R:R:N114	4.69	No	No	0	9	9
560	R:R:L117	R:R:N115	2.75	No	Yes	61	8	9
561	R:R:N115	R:R:N139	5.45	Yes	Yes	61	9	9
562	R:R:K118	R:R:Q116	5.42	No	No	0	4	6
563	R:R:H140	R:R:Q116	6.18	No	No	0	8	6
564	R:R:L117	R:R:N139	9.61	No	Yes	61	8	9
565	R:R:S143	R:R:T119	4.8	No	No	0	3	5
566	R:R:P121	R:R:V120	3.53	No	Yes	0	8	7
567	R:R:I141	R:R:V120	3.07	Yes	Yes	0	9	7
568	R:R:V120	R:R:V144	6.41	Yes	Yes	0	7	9
569	R:R:F149	R:R:V120	2.62	Yes	Yes	0	9	7
570	R:R:I125	R:R:P121	3.39	No	No	0	5	8
571	R:R:E123	R:R:S122	2.87	No	No	0	5	5
572	R:R:P145	R:R:S122	5.34	Yes	No	8	9	5
573	R:R:D147	R:R:S122	8.83	No	No	8	3	5
574	R:R:E123	R:R:R126	5.82	No	No	0	5	4
575	R:R:I125	R:R:L134	2.85	No	Yes	0	5	9
576	R:R:I125	R:R:L152	2.85	No	No	0	5	8
577	R:R:E150	R:R:R126	6.98	No	No	0	4	4
578	R:R:L128	R:R:L131	2.77	No	Yes	0	9	9
579	R:R:L131	R:R:L134	2.77	Yes	Yes	8	9	9
580	R:R:L131	R:R:L152	2.77	Yes	No	0	9	8
581	R:R:Q132	R:R:R156	8.18	No	Yes	0	8	9
582	R:R:H157	R:R:S133	5.58	Yes	No	0	9	9
583	R:R:L134	R:R:L136	11.07	Yes	No	0	9	9
584	R:R:F149	R:R:L134	3.65	Yes	Yes	8	9	9
585	R:R:L134	R:R:L158	2.77	Yes	Yes	8	9	9
586	R:R:D137	R:R:R135	4.76	Yes	Yes	1	9	9
587	R:R:R135	R:R:W159	17.99	Yes	Yes	1	9	9
588	R:R:L136	R:R:N139	2.75	No	Yes	0	9	9
589	R:R:A138	R:R:D137	3.09	No	Yes	1	9	9
590	R:R:D137	R:R:D161	7.98	Yes	Yes	1	9	9
591	R:R:I141	R:R:N139	2.83	Yes	Yes	0	9	9
592	R:R:I141	R:R:N163	11.33	Yes	No	0	9	9
593	R:R:I141	R:R:L165	2.85	Yes	No	0	9	9
594	R:R:S143	R:R:T142	3.2	No	No	0	3	6
595	R:R:P145	R:R:V144	3.53	Yes	Yes	8	9	9
596	R:R:S148	R:R:V144	3.23	No	Yes	8	8	9
597	R:R:P172	R:R:V144	3.53	Yes	Yes	8	9	9
598	R:R:D147	R:R:P145	3.22	No	Yes	8	3	9
599	R:R:P145	R:R:S148	3.56	Yes	No	8	9	8
600	R:R:E146	R:R:H171	7.39	No	Yes	8	4	1
601	R:R:E146	R:R:P172	3.14	No	Yes	8	4	9
602	R:R:D147	R:R:E150	3.9	No	No	0	3	4
603	R:R:F149	R:R:S148	11.89	Yes	No	8	9	8
604	R:R:F149	R:R:L158	3.65	Yes	Yes	8	9	9
605	R:R:F149	R:R:L176	6.09	Yes	Yes	0	9	9
606	R:R:E150	R:R:N175	2.63	No	No	0	4	4
607	R:R:L152	R:R:L155	2.77	No	No	0	8	9
608	R:R:Q154	R:R:V153	2.87	No	No	0	8	3
609	R:R:Q154	R:R:R156	3.5	No	Yes	0	8	9
610	R:R:L155	R:R:L176	5.54	No	Yes	0	9	9
611	R:R:H157	R:R:R156	5.64	Yes	Yes	0	9	9
612	R:R:Q180	R:R:R156	7.01	Yes	Yes	0	9	9
613	R:R:H157	R:R:W159	3.17	Yes	Yes	0	9	9
614	R:R:A181	R:R:H157	2.93	No	Yes	0	9	9
615	R:R:L158	R:R:L160	2.77	Yes	No	0	9	9
616	R:R:L158	R:R:L182	4.15	Yes	Yes	0	9	8
617	R:R:D161	R:R:W159	4.47	Yes	Yes	1	9	9
618	R:R:T183	R:R:W159	3.64	Yes	Yes	1	9	9
619	R:R:L160	R:R:N163	4.12	No	No	0	9	9
620	R:R:L160	R:R:L184	4.15	No	Yes	0	9	9
621	R:R:D161	R:R:T183	7.23	Yes	Yes	1	9	9
622	R:R:A185	R:R:D161	4.63	No	Yes	0	9	9
623	R:R:D162	R:R:L186	8.14	No	No	0	9	9
624	R:R:N163	R:R:N187	4.09	No	No	0	9	9
625	R:R:K188	R:R:S164	4.59	No	No	0	4	5
626	R:R:L165	R:R:N187	6.87	No	No	0	9	9
627	R:R:K188	R:R:T166	4.5	No	No	0	4	6
628	R:R:P169	R:R:V168	3.53	No	Yes	0	9	8
629	R:R:I189	R:R:V168	3.07	No	Yes	0	9	8
630	R:R:P193	R:R:V168	3.53	No	Yes	0	9	8
631	R:R:F197	R:R:V168	3.93	Yes	Yes	0	9	8
632	R:R:P169	R:R:P172	5.84	No	Yes	0	9	9
633	R:R:L173	R:R:P169	3.28	No	No	0	9	9
634	R:R:H171	R:R:P172	4.58	Yes	Yes	8	1	9
635	R:R:H171	R:R:S174	6.97	Yes	No	8	1	5
636	R:R:H171	R:R:N175	3.83	Yes	No	8	1	4
637	R:R:L173	R:R:L200	2.77	No	No	0	9	9
638	R:R:N175	R:R:S174	4.47	No	No	8	4	5
639	R:R:L176	R:R:L179	4.15	Yes	No	0	9	9
640	R:R:N199	R:R:P177	4.89	No	No	0	9	4
641	R:R:L179	R:R:L200	5.54	No	No	0	9	9
642	R:R:Q180	R:R:V204	2.87	Yes	Yes	1	9	9
643	R:R:L182	R:R:L184	4.15	Yes	Yes	0	8	9
644	R:R:F197	R:R:L182	3.65	Yes	Yes	0	9	8
645	R:R:L182	R:R:L206	4.15	Yes	No	0	8	9
646	R:R:H207	R:R:T183	5.48	Yes	Yes	1	9	9
647	R:R:I189	R:R:L184	2.85	No	Yes	0	9	9
648	R:R:L184	R:R:L208	4.15	Yes	Yes	0	9	9
649	R:R:A185	R:R:H209	5.85	No	Yes	0	9	9
650	R:R:L186	R:R:N210	8.24	No	Yes	1	9	9
651	R:R:N187	R:R:N211	2.72	No	Yes	0	9	9
652	R:R:K188	R:R:K212	2.87	No	No	0	4	5
653	R:R:I189	R:R:N211	7.08	No	Yes	0	9	9
654	R:R:R214	R:R:S190	2.64	No	No	0	3	3
655	R:R:I192	R:R:P193	3.39	Yes	No	0	8	9
656	R:R:F197	R:R:I192	3.77	Yes	Yes	0	9	8
657	R:R:I192	R:R:I213	2.94	Yes	Yes	2	8	9
658	R:R:I192	R:R:L216	2.85	Yes	Yes	2	8	6
659	R:R:C220	R:R:I192	3.27	Yes	Yes	2	5	8
660	R:R:A196	R:R:P193	3.74	No	No	0	9	9
661	R:R:D194	R:R:S217	11.78	No	No	0	8	6
662	R:R:D194	R:R:H219	2.52	No	Yes	0	8	5
663	R:R:F195	R:R:T198	3.89	No	No	0	2	4
664	R:R:F195	R:R:H219	7.92	No	Yes	62	2	5
665	R:R:D222	R:R:F195	5.97	No	No	62	4	2
666	R:R:A196	R:R:F197	2.77	No	Yes	0	9	9
667	R:R:F197	R:R:L200	4.87	Yes	No	0	9	9
668	R:R:L203	R:R:L224	4.15	No	No	0	9	9
669	R:R:L203	R:R:L227	2.77	No	No	0	9	9
670	R:R:V204	R:R:V205	4.81	Yes	Yes	1	9	9
671	R:R:E228	R:R:V204	5.7	No	Yes	0	9	9
672	R:R:H207	R:R:V205	4.15	Yes	Yes	1	9	9
673	R:R:T229	R:R:V205	7.93	Yes	Yes	1	9	9
674	R:R:L206	R:R:L208	9.69	No	Yes	0	9	9
675	R:R:L206	R:R:L230	4.15	No	Yes	0	9	9
676	R:R:H207	R:R:H209	4.78	Yes	Yes	1	9	9
677	R:R:H207	R:R:T229	2.74	Yes	Yes	1	9	9
678	R:R:D231	R:R:H207	15.13	Yes	Yes	1	9	9
679	R:R:L208	R:R:N211	2.75	Yes	Yes	2	9	9
680	R:R:I213	R:R:L208	2.85	Yes	Yes	2	9	9
681	R:R:L208	R:R:L232	2.77	Yes	No	0	9	9
682	R:R:H209	R:R:N210	7.65	Yes	Yes	1	9	9
683	R:R:D231	R:R:H209	2.52	Yes	Yes	1	9	9
684	R:R:H209	R:R:N233	5.1	Yes	Yes	1	9	9
685	R:R:N210	R:R:Y234	11.63	Yes	No	1	9	6
686	R:R:I213	R:R:N211	7.08	Yes	Yes	2	9	9
687	R:R:N211	R:R:N235	5.45	Yes	Yes	2	9	9
688	R:R:I213	R:R:L216	2.85	Yes	Yes	2	9	6
689	R:R:I213	R:R:N235	11.33	Yes	Yes	2	9	9
690	R:R:I213	R:R:L237	2.85	Yes	Yes	2	9	8
691	R:R:C220	R:R:L216	4.76	Yes	Yes	2	5	6
692	R:R:L216	R:R:L237	2.77	Yes	Yes	2	6	8
693	R:R:L216	R:R:P241	3.28	Yes	Yes	2	6	9
694	R:R:H219	R:R:Q218	13.6	Yes	No	0	5	3
695	R:R:D222	R:R:H219	13.87	No	Yes	62	4	5
696	R:R:C220	R:R:F221	11.17	Yes	Yes	0	5	9
697	R:R:F221	R:R:L224	3.65	Yes	No	0	9	9
698	R:R:F221	R:R:L230	6.09	Yes	Yes	0	9	9
699	R:R:F221	R:R:L247	3.65	Yes	No	0	9	9
700	R:R:A246	R:R:D222	3.09	No	No	0	5	4
701	R:R:D225	R:R:P248	3.22	No	No	0	4	4
702	R:R:E228	R:R:K251	10.8	No	Yes	0	9	9
703	R:R:D231	R:R:T229	4.34	Yes	Yes	1	9	9
704	R:R:E252	R:R:T229	4.23	No	Yes	0	9	9
705	R:R:L230	R:R:L232	4.15	Yes	No	0	9	9
706	R:R:L230	R:R:L253	4.15	Yes	Yes	0	9	9
707	R:R:D231	R:R:N233	4.04	Yes	Yes	1	9	9
708	R:R:L232	R:R:N235	6.87	No	Yes	0	9	9
709	R:R:H256	R:R:N233	14.03	Yes	Yes	1	9	9
710	R:R:H256	R:R:Y234	6.53	Yes	No	1	9	6
711	R:R:S257	R:R:Y234	19.08	No	No	1	8	6
712	R:R:L237	R:R:N235	2.75	Yes	Yes	2	8	9
713	R:R:L237	R:R:P241	3.28	Yes	Yes	2	8	9
714	R:R:L237	R:R:N258	4.12	Yes	Yes	2	8	9
715	R:R:F240	R:R:P241	8.67	Yes	Yes	2	9	9
716	R:R:F240	R:R:F255	6.43	Yes	Yes	2	9	9
717	R:R:F240	R:R:I260	2.51	Yes	Yes	2	9	9
718	R:R:F240	R:R:I263	2.51	Yes	No	2	9	9
719	R:R:F240	R:R:P264	8.67	Yes	No	2	9	9
720	R:R:A267	R:R:F240	4.16	No	Yes	2	9	9
721	R:R:F240	R:R:F268	3.22	Yes	Yes	2	9	9
722	R:R:I244	R:R:P241	6.77	No	Yes	0	8	9
723	R:R:I244	R:R:L253	5.71	No	Yes	0	8	9
724	R:R:I244	R:R:N271	2.83	No	Yes	0	8	9
725	R:R:L247	R:R:L250	5.54	No	No	0	9	9
726	R:R:L250	R:R:N271	6.87	No	Yes	2	9	9
727	R:R:L250	R:R:L274	4.15	No	Yes	2	9	9
728	R:R:E252	R:R:K251	6.75	No	Yes	0	9	9
729	R:R:K251	R:R:R275	3.71	Yes	No	0	9	5
730	R:R:F255	R:R:L253	6.09	Yes	Yes	2	9	9
731	R:R:F268	R:R:L253	3.65	Yes	Yes	2	9	9
732	R:R:F255	R:R:N258	6.04	Yes	Yes	2	9	9
733	R:R:F255	R:R:I260	2.51	Yes	Yes	2	9	9
734	R:R:F255	R:R:F268	4.29	Yes	Yes	2	9	9
735	R:R:F255	R:R:I277	2.51	Yes	Yes	2	9	8
736	R:R:H256	R:R:S257	4.18	Yes	No	1	9	8
737	R:R:H256	R:R:Y280	27.22	Yes	No	0	9	7
738	R:R:I260	R:R:N258	4.25	Yes	Yes	2	9	9
739	R:R:N258	R:R:N282	8.17	Yes	Yes	2	9	9
740	R:R:I260	R:R:N282	4.25	Yes	Yes	2	9	9
741	R:R:I260	R:R:L284	2.85	Yes	No	2	9	8
742	R:R:S261	R:R:V262	4.85	No	No	0	4	5
743	R:R:I263	R:R:P264	3.39	No	No	2	9	9
744	R:R:I263	R:R:L284	4.28	No	No	2	9	8
745	R:R:A267	R:R:P264	3.74	No	No	2	9	9
746	R:R:D265	R:R:G288	5.03	No	No	0	8	9
747	R:R:F268	R:R:N271	3.62	Yes	Yes	2	9	9
748	R:R:F268	R:R:L274	4.87	Yes	Yes	2	9	9
749	R:R:F268	R:R:I277	2.51	Yes	Yes	2	9	8
750	R:R:L274	R:R:N271	4.12	Yes	Yes	2	9	9
751	R:R:L273	R:R:P272	4.93	No	No	0	6	8
752	R:R:I277	R:R:L274	8.56	Yes	Yes	2	8	9
753	R:R:R275	R:R:T276	5.17	No	No	0	5	8
754	R:R:D297	R:R:R275	11.91	No	No	0	5	5
755	R:R:H278	R:R:T276	5.48	No	No	0	8	8
756	R:R:I277	R:R:L279	4.28	Yes	No	0	8	8
757	R:R:I303	R:R:L279	4.28	Yes	No	0	8	8
758	R:R:D281	R:R:Y280	6.9	No	No	0	8	7
759	R:R:L284	R:R:N282	2.75	No	Yes	2	8	9
760	R:R:M308	R:R:S285	3.07	No	No	0	4	8
761	R:R:F286	R:R:G288	6.02	No	No	0	4	9
762	R:R:I303	R:R:V287	3.07	Yes	No	0	8	9
763	R:R:N289	R:R:Q311	10.56	No	No	0	4	4
764	R:R:N289	R:R:N314	6.81	No	No	0	4	7
765	R:R:H293	R:R:S290	5.58	Yes	No	0	7	8
766	R:R:A291	R:R:F292	2.77	No	No	0	9	9
767	R:R:F292	R:R:L295	4.87	No	No	0	9	9
768	R:R:F292	R:R:L301	4.87	No	No	0	9	9
769	R:R:H293	R:R:N294	2.55	Yes	No	0	7	6
770	R:R:H293	R:R:N314	8.93	Yes	No	63	7	7
771	R:R:H293	R:R:T316	2.74	Yes	No	63	7	5
772	R:R:L295	R:R:L298	4.15	No	No	32	9	9
773	R:R:L295	R:R:T318	2.95	No	Yes	32	9	8
774	R:R:D297	R:R:S296	2.94	No	No	0	5	9
775	R:R:L298	R:R:T318	2.95	No	Yes	32	9	8
776	R:R:S300	R:R:V302	3.23	No	No	0	9	7
777	R:R:S300	R:R:S323	3.26	No	No	0	9	7
778	R:R:I303	R:R:L301	4.28	Yes	No	0	8	9
779	R:R:L301	R:R:L324	4.15	No	No	0	9	9
780	R:R:R304	R:R:V302	5.23	No	No	31	8	7
781	R:R:T325	R:R:V302	9.52	Yes	No	31	8	7
782	R:R:I303	R:R:L326	2.85	Yes	Yes	0	8	7
783	R:R:R304	R:R:T325	2.59	No	Yes	31	8	8
784	R:R:R304	R:R:T327	14.23	No	Yes	31	8	9
785	R:R:K330	R:R:Q310	2.71	No	No	0	5	5
786	R:R:F312	R:R:P313	10.11	Yes	No	0	8	9
787	R:R:F312	R:R:L326	3.65	Yes	Yes	19	8	7
788	R:R:F312	R:R:I331	2.51	Yes	Yes	19	8	8
789	R:R:F312	R:R:P335	13	Yes	No	0	8	8
790	R:R:L315	R:R:P313	3.28	No	No	0	9	9
791	R:R:N314	R:R:T316	11.7	No	No	63	7	5
792	R:R:L315	R:R:T318	4.42	No	Yes	0	9	8
793	R:R:L315	R:R:Q342	2.66	No	Yes	0	9	8
794	R:R:L321	R:R:T318	4.42	No	Yes	32	8	8
795	R:R:H320	R:R:V319	4.15	No	No	0	7	4
796	R:R:E341	R:R:V319	2.85	No	No	0	5	4
797	R:R:H320	R:R:M344	6.57	No	No	0	7	4
798	R:R:L321	R:R:Q342	3.99	No	Yes	32	8	8
799	R:R:L321	R:R:L345	2.77	No	No	32	8	9
800	R:R:E322	R:R:R346	6.98	No	No	0	8	7
801	R:R:S323	R:R:T347	4.8	No	No	0	7	6
802	R:R:L324	R:R:L326	4.15	No	Yes	0	9	7
803	R:R:L324	R:R:L348	4.15	No	No	0	9	9
804	R:R:T325	R:R:T327	3.14	Yes	Yes	31	8	9
805	R:R:D349	R:R:T325	7.23	Yes	Yes	31	8	8
806	R:R:L326	R:R:T329	2.95	Yes	No	19	7	8
807	R:R:I331	R:R:L326	4.28	Yes	Yes	19	8	7
808	R:R:G328	R:R:T327	3.64	No	Yes	0	7	9
809	R:R:D349	R:R:T327	4.34	Yes	Yes	31	8	9
810	R:R:S351	R:R:T327	4.8	No	Yes	31	9	9
811	R:R:I331	R:R:T329	6.08	Yes	No	19	8	8
812	R:R:N353	R:R:T329	8.77	Yes	No	19	9	8
813	R:R:K330	R:R:N354	6.99	No	No	0	5	3
814	R:R:I331	R:R:N353	8.5	Yes	Yes	19	8	9
815	R:R:I334	R:R:P335	3.39	No	No	0	7	8
816	R:R:I334	R:R:L350	4.28	No	Yes	0	7	9
817	R:R:I334	R:R:P359	6.77	No	Yes	0	7	9
818	R:R:N337	R:R:P335	4.89	No	No	0	3	8
819	R:R:N336	R:R:P359	3.26	No	Yes	0	1	9
820	R:R:L338	R:R:Q342	3.99	No	Yes	0	5	8
821	R:R:C339	R:R:C364	7.28	No	No	64	9	9
822	R:R:E341	R:R:Q340	5.1	No	No	0	5	4
823	R:R:E341	R:R:Q342	6.37	No	Yes	0	5	8
824	R:R:L345	R:R:Q342	3.99	No	Yes	32	9	8
825	R:R:L345	R:R:L367	4.15	No	No	0	9	7
826	R:R:E368	R:R:R346	6.98	No	No	0	7	7
827	R:R:L348	R:R:L350	4.15	No	Yes	0	9	9
828	R:R:D349	R:R:S351	2.94	Yes	No	31	8	9
829	R:R:D349	R:R:S371	4.42	Yes	No	0	8	6
830	R:R:L350	R:R:N353	5.49	Yes	Yes	0	9	9
831	R:R:L350	R:R:L372	2.77	Yes	Yes	0	9	8
832	R:R:S351	R:R:Y352	8.9	No	No	0	9	7
833	R:R:R374	R:R:Y352	19.55	No	No	0	8	7
834	R:R:I355	R:R:N353	4.25	No	Yes	19	8	9
835	R:R:N353	R:R:N375	2.72	Yes	Yes	19	9	9
836	R:R:N354	R:R:Q376	5.28	No	No	0	3	4
837	R:R:I355	R:R:N375	15.58	No	Yes	19	8	9
838	R:R:D357	R:R:R356	4.76	No	No	0	3	3
839	R:R:Q376	R:R:R356	3.5	No	No	0	4	3
840	R:R:R356	R:R:Y378	4.12	No	No	0	3	1
841	R:R:L358	R:R:P359	3.28	No	Yes	0	8	9
842	R:R:L358	R:R:L372	4.15	No	Yes	0	8	8
843	R:R:I377	R:R:L358	4.28	No	No	0	7	8
844	R:R:F361	R:R:P359	4.33	No	Yes	0	6	9
845	R:R:N362	R:R:S360	4.47	No	No	0	4	7
846	R:R:F361	R:R:I370	2.51	No	Yes	0	6	7
847	R:R:G363	R:R:H365	4.77	Yes	No	0	4	3
848	R:R:G387	R:R:H365	3.18	No	No	0	5	3
849	R:R:H365	R:R:I389	6.63	No	No	0	3	3
850	R:R:I370	R:R:L367	5.71	Yes	No	0	7	7
851	R:R:L367	R:R:L388	2.77	No	Yes	0	7	8
852	R:R:E368	R:R:E369	10.15	No	No	0	7	7
853	R:R:E368	R:R:R392	8.14	No	No	0	7	6
854	R:R:E369	R:R:I393	2.73	No	No	0	7	4
855	R:R:I370	R:R:L372	4.28	Yes	Yes	0	7	8
856	R:R:I370	R:R:L391	2.85	Yes	Yes	0	7	9
857	R:R:Q373	R:R:S371	5.78	No	No	0	8	6
858	R:R:L372	R:R:N375	4.12	Yes	Yes	0	8	9
859	R:R:L372	R:R:L396	2.77	Yes	Yes	0	8	9
860	R:R:Q373	R:R:R374	9.35	No	No	0	8	8
861	R:R:Q373	R:R:S397	5.78	No	No	0	8	8
862	R:R:R374	R:R:R398	8.53	No	No	0	8	5
863	R:R:I377	R:R:N375	5.66	No	Yes	19	7	9
864	R:R:N375	R:R:N399	4.09	Yes	No	19	9	9
865	R:R:I377	R:R:N399	11.33	No	No	19	7	9
866	R:R:Q379	R:R:Y378	13.53	No	No	0	5	1
867	R:R:H402	R:R:Q379	7.42	No	No	0	3	5
868	R:R:I380	R:R:T384	3.04	No	No	0	7	8
869	R:R:I380	R:R:I401	2.94	No	Yes	0	7	8
870	R:R:E382	R:R:H405	25.85	No	No	0	4	6
871	R:R:G383	R:R:Q386	4.93	No	No	0	4	4
872	R:R:F385	R:R:T384	23.35	No	No	0	9	8
873	R:R:F385	R:R:L388	4.87	No	Yes	0	9	8
874	R:R:F385	R:R:L394	7.31	No	No	0	9	7
875	R:R:L388	R:R:L391	6.92	Yes	Yes	0	8	9
876	R:R:L391	R:R:L394	2.77	Yes	No	0	9	7
877	R:R:I415	R:R:L391	2.85	Yes	Yes	0	7	9
878	R:R:R392	T:T:E67	12.79	No	No	65	6	9
879	R:R:R392	T:T:T75	12.94	No	No	65	6	8
880	R:R:D395	R:R:I393	2.8	No	No	0	9	4
881	R:R:I393	R:R:N417	2.83	No	No	0	4	7
882	R:R:L394	R:R:L396	4.15	No	Yes	0	7	9
883	R:R:D395	R:R:D419	2.66	No	No	0	9	9
884	R:R:I401	R:R:L396	2.85	Yes	Yes	0	8	9
885	R:R:L396	R:R:V420	2.98	Yes	No	0	9	6
886	R:R:R398	R:R:S397	3.95	No	No	0	5	8
887	R:R:F422	R:R:R398	9.62	Yes	No	0	4	5
888	R:R:N399	R:R:N423	5.45	No	No	0	9	9
889	R:R:I401	R:R:I404	2.94	Yes	Yes	0	8	7
890	R:R:I401	R:R:N423	9.91	Yes	No	0	8	9
891	R:R:E403	R:R:H402	8.62	No	No	0	2	3
892	R:R:F409	R:R:I404	3.77	Yes	Yes	0	8	7
893	R:R:I404	R:R:L425	2.85	Yes	No	0	7	9
894	R:R:I404	R:R:P429	6.77	Yes	No	0	7	9
895	R:R:H405	R:R:S406	5.58	No	No	39	6	3
896	R:R:H405	R:R:R407	4.51	No	Yes	39	6	4
897	R:R:R407	R:R:S406	2.64	Yes	No	39	4	3
898	R:R:A410	R:R:R407	4.15	No	Yes	39	3	4
899	R:R:E431	R:R:R407	11.63	No	Yes	39	3	4
900	R:R:A408	R:R:F409	2.77	No	Yes	0	8	8
901	R:R:F409	R:R:L412	3.65	Yes	No	0	8	8
902	R:R:F409	R:R:L418	6.09	Yes	Yes	23	8	9
903	R:R:F409	R:R:L433	9.74	Yes	Yes	23	8	9
904	R:R:A410	R:R:E431	4.53	No	No	39	3	3
905	R:R:I415	R:R:L412	12.85	Yes	No	0	7	8
906	R:R:G413	R:R:P414	4.06	No	No	0	3	5
907	R:R:I415	R:R:L418	2.85	Yes	Yes	23	7	9
908	R:R:I415	R:R:L436	2.85	Yes	Yes	23	7	8
909	R:R:N437	R:R:T416	2.92	No	No	66	5	4
910	R:R:T416	T:T:Y77	3.75	No	Yes	66	4	6
911	R:R:N417	R:R:Q438	17.17	No	Yes	30	7	9
912	R:R:K440	R:R:N417	4.2	Yes	No	30	8	7
913	R:R:L418	R:R:V420	2.98	Yes	No	0	9	6
914	R:R:L418	R:R:L433	2.77	Yes	Yes	23	9	9
915	R:R:L418	R:R:L436	2.77	Yes	Yes	23	9	8
916	R:R:L418	R:R:L439	4.15	Yes	Yes	23	9	8
917	R:R:D419	R:R:S421	5.89	No	No	0	9	7
918	R:R:D419	R:R:K440	20.74	No	Yes	0	9	8
919	R:R:N423	R:R:V420	4.43	No	No	0	9	6
920	R:R:F422	R:R:S421	10.57	Yes	No	43	4	7
921	R:R:S421	R:R:V442	3.23	No	No	43	7	4
922	R:R:F422	R:R:V442	2.62	Yes	No	43	4	4
923	R:R:F422	R:R:G443	6.02	Yes	No	43	4	8
924	R:R:L425	R:R:N444	12.36	No	No	0	9	9
925	R:R:L425	R:R:L447	5.54	No	No	0	9	7
926	R:R:K446	R:R:T426	4.5	No	No	0	3	4
927	R:R:F428	R:R:T430	2.59	Yes	No	0	4	5
928	R:R:F428	R:R:L439	7.31	Yes	Yes	23	4	8
929	R:R:F428	R:R:L441	6.09	Yes	No	23	4	8
930	R:R:F428	R:R:L451	4.87	Yes	No	0	4	7
931	R:R:D455	R:R:T430	11.56	No	No	0	4	5
932	R:R:F456	R:R:T430	6.49	Yes	No	0	5	5
933	R:R:L433	R:R:L436	5.54	Yes	Yes	23	9	8
934	R:R:F456	R:R:L433	4.87	Yes	Yes	0	5	9
935	R:R:G435	R:R:N458	5.09	No	No	0	4	4
936	R:R:L436	R:R:L439	4.15	Yes	Yes	23	8	8
937	R:R:L436	R:R:L459	2.77	Yes	No	0	8	7
938	R:R:N437	T:T:Y77	6.98	No	Yes	66	5	6
939	R:R:N437	T:T:T78	2.92	No	Yes	0	5	9
940	R:R:K440	R:R:Q438	10.85	Yes	Yes	30	8	9
941	R:R:Q438	R:R:S461	4.33	Yes	No	0	9	6
942	R:R:L439	R:R:L441	6.92	Yes	No	23	8	8
943	R:R:K440	R:R:S463	3.06	Yes	No	30	8	8
944	R:R:L441	R:R:N444	2.75	No	No	0	8	9
945	R:R:G443	R:R:V442	3.68	No	No	43	8	4
946	R:R:N444	R:R:P465	3.26	No	No	0	9	9
947	R:R:L447	R:R:P465	3.28	No	No	0	7	9
948	R:R:K448	R:R:Y466	7.17	No	Yes	0	7	6
949	R:R:K448	R:R:T614	4.5	No	No	0	7	4
950	R:R:E449	R:R:L451	5.3	No	No	0	4	7
951	R:R:A453	R:R:F473	5.55	No	Yes	0	4	8
952	R:R:D455	R:R:K454	4.15	No	No	0	4	5
953	R:R:F456	R:R:L459	7.31	Yes	No	0	5	7
954	R:R:F456	R:R:F473	4.29	Yes	Yes	0	5	8
955	R:R:N458	R:R:V457	2.96	No	No	0	4	4
956	R:R:N458	T:T:Y77	5.81	No	Yes	0	4	6
957	R:R:R460	T:T:T78	3.88	No	Yes	0	9	9
958	R:R:L462	R:R:V464	4.47	No	No	0	7	7
959	R:R:F473	R:R:L462	3.65	Yes	No	0	8	7
960	R:R:S463	R:R:T523	7.99	No	No	30	8	6
961	R:R:P524	R:R:S463	3.56	No	No	30	9	8
962	R:R:P465	R:R:V464	3.53	No	No	0	9	7
963	R:R:Q469	R:R:V464	7.16	No	No	0	9	7
964	R:R:Q469	R:R:Y466	6.76	No	Yes	0	9	6
965	R:R:I610	R:R:Y466	4.84	No	Yes	0	7	6
966	R:R:K530	R:R:Y468	21.5	No	Yes	11	8	9
967	R:R:G609	R:R:Y468	4.35	No	Yes	0	9	9
968	R:R:I610	R:R:Y468	6.04	No	Yes	0	7	9
969	R:R:E613	R:R:Y468	13.47	Yes	Yes	11	9	9
970	R:R:P691	R:R:Y468	4.17	Yes	Yes	11	9	9
971	R:R:C470	R:R:C522	5.46	No	No	0	9	9
972	R:R:C471	R:R:T526	5.07	No	No	0	9	8
973	R:R:C471	R:R:C532	5.46	No	No	0	9	9
974	R:R:F473	R:R:I520	8.79	Yes	No	0	8	5
975	R:R:I518	R:R:I520	2.94	No	No	0	4	5
976	R:R:H521	R:R:I519	7.95	No	No	0	8	4
977	R:R:I519	T:T:F60	6.28	No	No	0	4	8
978	R:R:I519	T:T:R208	2.51	No	No	0	4	9
979	R:R:P524	R:R:T523	3.5	No	No	30	9	6
980	R:R:K530	R:R:T526	3	No	No	0	8	8
981	R:R:A528	R:R:P779	3.74	No	No	9	9	8
982	R:R:A528	R:R:E780	7.54	No	Yes	9	9	8
983	R:R:F529	R:R:P697	2.89	No	Yes	0	8	7
984	R:R:F529	R:R:P779	4.33	No	No	0	8	8
985	R:R:F529	R:R:M782	8.71	No	No	0	8	5
986	R:R:E613	R:R:K530	5.4	Yes	No	11	9	8
987	R:R:F605	R:R:P531	8.67	Yes	No	0	9	8
988	R:R:A606	R:R:C532	3.61	No	No	0	6	9
989	R:R:E533	R:R:Y534	3.37	No	Yes	11	4	4
990	R:R:E533	R:R:G603	4.91	No	No	11	4	9
991	R:R:W602	R:R:Y534	7.72	No	Yes	0	4	4
992	R:R:G603	R:R:Y534	5.79	No	Yes	11	9	4
993	R:R:L535	R:R:L536	4.15	Yes	Yes	11	9	5
994	R:R:L535	R:R:L594	2.77	Yes	No	0	9	9
995	R:R:D598	R:R:L535	4.07	Yes	Yes	11	9	9
996	R:R:F605	R:R:L535	7.31	Yes	Yes	11	9	9
997	R:R:L535	R:R:P691	3.28	Yes	Yes	11	9	9
998	R:R:L536	R:R:V545	4.47	Yes	No	0	5	8
999	R:R:D598	R:R:L536	10.86	Yes	Yes	11	9	5
1000	R:R:L536	R:R:L787	4.15	Yes	No	0	5	9
1001	R:R:M540	R:R:S538	7.67	Yes	No	0	5	9
1002	R:R:I541	R:R:S538	4.64	Yes	No	0	7	9
1003	R:R:M540	R:R:W539	12.8	Yes	No	0	5	9
1004	R:R:R542	R:R:W539	3	No	No	0	9	9
1005	R:R:L543	R:R:W539	3.42	No	No	0	5	9
1006	R:R:M540	T:T:F217	6.22	Yes	No	0	5	9
1007	R:R:M540	T:T:G220	5.24	Yes	No	0	5	9
1008	R:R:M540	T:T:A224	3.22	Yes	No	0	5	9
1009	R:R:I541	R:R:T544	3.04	Yes	No	9	7	9
1010	R:R:I541	T:T:Y216	18.13	Yes	No	9	7	9
1011	R:R:I541	T:T:L223	8.56	Yes	Yes	9	7	9
1012	R:R:D598	R:R:R542	3.57	Yes	No	0	9	9
1013	R:R:T544	R:R:V545	3.17	No	No	0	9	8
1014	R:R:T544	T:T:L223	4.42	No	Yes	9	9	9
1015	R:R:I548	R:R:V545	3.07	No	No	0	7	8
1016	R:R:F549	R:R:W546	9.02	Yes	No	44	5	9
1017	R:R:T595	R:R:W546	3.64	No	No	44	7	9
1018	R:R:F547	R:R:V551	9.18	No	Yes	0	4	6
1019	R:R:F547	T:T:L231	12.18	No	No	0	4	9
1020	R:R:I548	R:R:P791	5.08	No	Yes	0	7	9
1021	R:R:C795	R:R:I548	3.27	No	No	0	9	7
1022	R:R:F549	R:R:T591	2.59	Yes	No	0	5	7
1023	R:R:F549	R:R:G592	4.52	Yes	No	44	5	5
1024	R:R:F549	R:R:T595	12.97	Yes	No	44	5	7
1025	R:R:F555	R:R:V551	2.62	No	Yes	0	5	6
1026	R:R:A552	R:R:C795	3.61	No	No	0	8	9
1027	R:R:F554	R:R:F555	6.43	No	No	0	3	5
1028	R:R:F555	R:R:V799	5.24	No	No	0	5	9
1029	R:R:I560	R:R:N556	2.83	No	Yes	68	4	9
1030	R:R:N556	R:R:S581	10.43	Yes	No	68	9	7
1031	R:R:N556	R:R:N584	5.45	Yes	Yes	0	9	9
1032	R:R:L585	R:R:N556	6.87	No	Yes	0	4	9
1033	R:R:F808	R:R:L558	6.09	Yes	No	0	7	7
1034	R:R:S581	R:R:V559	6.46	No	No	0	7	8
1035	R:R:F564	R:R:I560	2.51	No	No	0	8	4
1036	R:R:I560	R:R:S581	6.19	No	No	68	4	7
1037	R:R:F808	R:R:T562	3.89	Yes	No	0	7	5
1038	R:R:F564	R:R:T563	6.49	No	No	0	8	4
1039	R:R:G578	R:R:T563	3.64	No	No	0	8	4
1040	R:R:L570	R:R:P571	3.28	No	No	0	4	7
1041	R:R:K574	R:R:P571	15.06	No	No	0	7	7
1042	R:R:F576	R:R:S572	3.96	Yes	No	33	6	6
1043	R:R:E642	R:R:S572	7.19	Yes	No	33	8	6
1044	R:R:F662	R:R:S572	6.61	No	No	0	4	6
1045	R:R:E642	R:R:S573	5.75	Yes	No	33	8	5
1046	R:R:R643	R:R:S573	5.27	Yes	No	33	8	5
1047	R:R:F576	R:R:L575	4.87	Yes	No	0	6	6
1048	R:R:E642	R:R:F576	5.83	Yes	Yes	33	8	6
1049	R:R:I577	R:R:Y801	12.09	No	Yes	0	5	9
1050	R:R:L579	R:R:L635	4.15	No	Yes	0	7	5
1051	R:R:I580	R:R:N584	4.25	No	Yes	0	7	9
1052	R:R:I580	R:R:L635	7.14	No	Yes	0	7	5
1053	R:R:I580	R:R:L636	5.71	No	No	0	7	9
1054	R:R:F586	R:R:V582	3.93	Yes	No	0	6	3
1055	R:R:S583	R:R:S628	4.89	No	No	0	5	8
1056	R:R:S583	R:R:S631	6.52	No	No	0	5	5
1057	R:R:A794	R:R:N584	3.13	No	Yes	0	8	9
1058	R:R:N584	R:R:P798	3.26	Yes	No	0	9	9
1059	R:R:F586	R:R:L624	4.87	Yes	No	0	6	5
1060	R:R:F586	R:R:F627	4.29	Yes	Yes	0	6	5
1061	R:R:F586	R:R:S628	2.64	Yes	No	0	6	8
1062	R:R:M587	R:R:S628	9.2	Yes	No	0	6	8
1063	R:R:F790	R:R:M587	7.46	No	Yes	67	5	6
1064	R:R:M587	R:R:P791	3.35	Yes	Yes	67	6	9
1065	R:R:A794	R:R:M587	3.22	No	Yes	0	8	6
1066	R:R:L594	R:R:Y590	14.07	No	No	0	9	5
1067	R:R:A625	R:R:Y590	5.34	No	No	0	7	5
1068	R:R:L694	R:R:Y590	8.21	Yes	No	0	7	5
1069	R:R:P791	R:R:T591	3.5	Yes	No	0	9	7
1070	R:R:G592	R:R:T595	3.64	No	No	44	5	7
1071	R:R:I593	R:R:L594	2.85	No	No	0	5	9
1072	R:R:L597	R:R:W612	10.25	No	Yes	0	8	9
1073	R:R:F605	R:R:S601	5.28	Yes	No	0	9	9
1074	R:R:F608	R:R:S601	2.64	No	No	0	4	9
1075	R:R:F608	R:R:R604	5.34	No	No	0	4	4
1076	R:R:F605	R:R:G609	3.01	Yes	No	0	9	9
1077	R:R:F605	R:R:P691	5.78	Yes	Yes	11	9	9
1078	R:R:E607	R:R:F608	13.99	No	No	0	1	4
1079	R:R:G617	R:R:W612	5.63	No	Yes	0	7	9
1080	R:R:A621	R:R:W612	2.59	No	Yes	0	5	9
1081	R:R:C693	R:R:W612	3.92	No	Yes	0	9	9
1082	R:R:C618	R:R:E613	3.04	No	Yes	0	9	9
1083	R:R:E613	R:R:P691	3.14	Yes	Yes	11	9	9
1084	R:R:G617	R:R:V620	3.68	No	No	0	7	3
1085	R:R:C618	R:R:C693	7.28	No	No	0	9	9
1086	R:R:K619	R:R:L681	2.82	No	No	0	4	6
1087	R:R:F623	R:R:T674	6.49	No	No	0	4	3
1088	R:R:F623	R:R:G677	3.01	No	No	0	4	8
1089	R:R:C678	R:R:F623	2.79	No	No	0	4	4
1090	R:R:G677	R:R:V626	3.68	No	No	0	8	6
1091	R:R:P695	R:R:V626	3.53	Yes	No	0	9	6
1092	R:R:F627	R:R:F670	8.57	Yes	Yes	0	5	3
1093	R:R:A673	R:R:F627	2.77	No	Yes	0	8	5
1094	R:R:F627	R:R:T674	3.89	Yes	No	0	5	3
1095	R:R:E630	R:R:S629	5.75	Yes	No	0	8	8
1096	R:R:F790	R:R:S629	5.28	No	No	0	5	8
1097	R:R:E630	R:R:F634	8.16	Yes	Yes	10	8	7
1098	R:R:A673	R:R:E630	3.02	No	Yes	10	8	8
1099	R:R:E630	R:R:L710	5.3	Yes	No	10	8	9
1100	R:R:E630	R:R:N714	9.2	Yes	Yes	10	8	9
1101	R:R:L635	R:R:S631	4.5	Yes	No	70	5	5
1102	R:R:F670	R:R:S631	2.64	Yes	No	70	3	5
1103	R:R:F634	R:R:I633	2.51	Yes	Yes	10	7	6
1104	R:R:I633	R:R:N714	5.66	Yes	Yes	10	6	9
1105	R:R:F718	R:R:I633	2.51	Yes	Yes	10	6	6
1106	R:R:I633	R:R:N756	4.25	Yes	No	10	6	9
1107	R:R:A673	R:R:F634	2.77	No	Yes	10	8	7
1108	R:R:F634	R:R:L713	6.09	Yes	No	0	7	5
1109	R:R:F670	R:R:L635	3.65	Yes	Yes	70	3	5
1110	R:R:L638	R:R:M637	5.65	No	No	0	7	5
1111	R:R:A639	R:R:V749	3.39	No	No	0	9	7
1112	R:R:M721	R:R:T640	7.53	No	No	10	7	7
1113	R:R:I724	R:R:T640	6.08	Yes	No	0	6	7
1114	R:R:I753	R:R:T640	3.04	No	No	10	9	7
1115	R:R:S644	R:R:V641	3.23	No	No	0	6	6
1116	R:R:E642	R:R:R643	15.12	Yes	Yes	33	8	8
1117	R:R:E642	R:R:S646	5.75	Yes	No	33	8	6
1118	R:R:R643	R:R:S646	7.91	Yes	No	33	8	6
1119	R:R:M745	R:R:R643	6.2	Yes	Yes	0	7	8
1120	R:R:I746	R:R:R643	3.76	No	Yes	0	7	8
1121	R:R:R643	R:R:V749	5.23	Yes	No	0	8	7
1122	R:R:I724	R:R:S644	3.1	Yes	No	0	6	6
1123	R:R:K660	R:R:N657	2.8	No	No	0	1	3
1124	R:R:F662	R:R:H658	6.79	No	No	0	4	4
1125	R:R:K660	R:R:L659	4.23	No	No	0	1	1
1126	R:R:K660	R:R:R663	4.95	No	No	0	1	4
1127	R:R:Q661	R:R:V664	4.3	No	No	0	5	2
1128	R:R:C678	R:R:L681	6.35	No	No	0	4	6
1129	R:R:C678	R:R:F682	2.79	No	No	0	4	3
1130	R:R:F679	R:R:P680	4.33	No	Yes	13	5	7
1131	R:R:F679	R:R:F706	3.22	No	Yes	13	5	5
1132	R:R:E686	R:R:P680	9.43	Yes	Yes	13	4	7
1133	R:R:P680	R:R:Y687	6.95	Yes	Yes	13	7	5
1134	R:R:F706	R:R:P680	11.56	Yes	Yes	13	5	7
1135	R:R:L681	R:R:Y687	4.69	No	Yes	0	6	5
1136	R:R:E686	R:R:H683	3.69	Yes	No	0	4	4
1137	R:R:E686	R:R:Y687	4.49	Yes	Yes	13	4	5
1138	R:R:E686	R:R:P695	4.72	Yes	Yes	13	4	9
1139	R:R:E686	R:R:S703	11.5	Yes	No	0	4	5
1140	R:R:P695	R:R:Y687	8.34	Yes	Yes	13	9	5
1141	R:R:A689	R:R:T698	5.03	No	No	0	4	4
1142	R:R:P691	R:R:S690	5.34	Yes	No	0	9	8
1143	R:R:L692	R:R:S690	4.5	Yes	No	0	7	8
1144	R:R:L692	R:R:L694	2.77	Yes	Yes	13	7	7
1145	R:R:L692	R:R:P697	3.28	Yes	Yes	13	7	7
1146	R:R:L692	R:R:L787	4.15	Yes	No	0	7	9
1147	R:R:F696	R:R:L694	6.09	No	Yes	13	7	7
1148	R:R:L694	R:R:P697	3.28	Yes	Yes	13	7	7
1149	R:R:F696	R:R:P695	5.78	No	Yes	13	7	9
1150	R:R:F706	R:R:P695	4.33	Yes	Yes	13	5	9
1151	R:R:F696	R:R:P697	14.45	No	Yes	13	7	7
1152	R:R:P702	R:R:T698	12.24	No	No	0	5	4
1153	R:R:E700	R:R:G699	3.27	No	No	0	3	4
1154	R:R:E700	R:R:P770	11	No	No	0	3	9
1155	R:R:E700	R:R:L771	11.93	No	No	0	3	7
1156	R:R:P702	R:R:T701	6.99	No	No	0	5	4
1157	R:R:F706	R:R:S703	3.96	Yes	No	0	5	5
1158	R:R:F706	R:R:T709	2.59	Yes	No	0	5	7
1159	R:R:L710	R:R:N714	2.75	No	Yes	10	9	9
1160	R:R:F768	R:R:V711	7.87	No	No	0	5	9
1161	R:R:L712	R:R:S715	3	No	No	0	8	7
1162	R:R:L712	R:R:L716	2.77	No	No	0	8	5
1163	R:R:L713	R:R:L716	4.15	No	No	0	5	5
1164	R:R:F760	R:R:N714	6.04	No	Yes	0	8	9
1165	R:R:F718	R:R:M721	4.98	Yes	No	10	6	7
1166	R:R:F718	R:R:N756	3.62	Yes	No	10	6	9
1167	R:R:C757	R:R:F718	4.19	No	Yes	10	9	6
1168	R:R:C761	R:R:F718	2.79	No	Yes	10	7	6
1169	R:R:I753	R:R:M721	10.2	No	No	10	9	7
1170	R:R:I724	R:R:L728	4.28	Yes	No	0	6	9
1171	R:R:T726	R:R:Y725	8.74	No	No	0	7	8
1172	R:R:Y725	R:R:Y729	9.93	No	No	0	8	9
1173	R:R:F754	R:R:Y725	22.69	Yes	No	0	8	8
1174	R:R:E739	R:R:Q742	8.92	No	No	0	4	7
1175	R:R:M745	R:R:S744	3.07	Yes	No	0	7	5
1176	R:R:P806	R:R:S744	3.56	No	No	0	9	5
1177	R:R:M745	R:R:N805	2.8	Yes	No	0	7	8
1178	R:R:K807	R:R:M745	8.64	No	Yes	0	6	7
1179	R:R:K747	R:R:W751	9.28	No	Yes	0	7	8
1180	R:R:H748	R:R:L752	3.86	No	No	0	9	9
1181	R:R:H748	R:R:Y801	9.8	No	Yes	69	9	9
1182	R:R:H748	R:R:N805	19.13	No	No	69	9	8
1183	R:R:A750	R:R:F754	2.77	No	Yes	0	9	8
1184	R:R:F804	R:R:W751	8.02	No	Yes	5	9	8
1185	R:R:W751	W:W:?1	6.81	Yes	Yes	5	8	0
1186	R:R:L752	R:R:N797	5.49	No	No	0	9	9
1187	R:R:F754	R:R:I753	6.28	Yes	No	0	8	9
1188	R:R:C757	R:R:C761	7.28	No	No	10	9	7
1189	R:R:F759	R:R:I758	3.77	Yes	No	0	9	7
1190	R:R:F759	R:R:L792	13.4	Yes	No	71	9	9
1191	R:R:F759	R:R:P793	10.11	Yes	No	71	9	9
1192	R:R:F759	R:R:L796	6.09	Yes	No	0	9	8
1193	R:R:F766	R:R:I781	2.51	No	Yes	0	9	8
1194	R:R:F766	R:R:V785	7.87	No	No	0	9	7
1195	R:R:F768	R:R:S767	3.96	No	No	0	5	8
1196	R:R:F768	R:R:L771	3.65	No	No	0	5	7
1197	R:R:A769	R:R:I777	3.25	No	No	0	8	6
1198	R:R:M782	R:R:P770	3.35	No	No	0	5	9
1199	R:R:I772	R:R:L771	2.85	No	No	0	8	7
1200	R:R:I772	R:R:I775	4.42	No	No	0	8	4
1201	R:R:I775	R:R:I777	4.42	No	No	0	4	6
1202	R:R:E780	R:R:S778	5.75	Yes	No	0	8	6
1203	R:R:I781	R:R:S778	4.64	Yes	No	0	8	6
1204	R:R:E780	R:R:P779	11	Yes	No	9	8	8
1205	R:R:E780	T:T:E215	5.07	Yes	Yes	9	8	9
1206	R:R:I781	T:T:E215	2.73	Yes	Yes	0	8	9
1207	R:R:K783	R:R:L787	5.64	No	No	0	9	9
1208	R:R:S784	T:T:Y216	12.72	No	No	9	7	9
1209	R:R:S784	T:T:M219	3.07	No	Yes	9	7	9
1210	R:R:F789	R:R:V785	5.24	Yes	No	0	7	7
1211	R:R:F789	R:R:I788	2.51	Yes	No	0	7	7
1212	R:R:I788	T:T:L223	5.71	No	Yes	0	7	9
1213	R:R:F790	R:R:P791	4.33	No	Yes	67	5	9
1214	R:R:L792	R:R:P793	3.28	No	No	71	9	9
1215	R:R:L796	R:R:N797	5.49	No	No	0	8	9
1216	R:R:L796	R:R:L800	2.77	No	No	0	8	9
1217	R:R:F804	R:R:L800	10.96	No	No	0	9	9
1218	R:R:N805	R:R:Y801	25.59	No	Yes	69	8	9
1219	R:R:F808	R:R:Y801	6.19	Yes	Yes	0	7	9
1220	R:R:F803	R:R:V802	7.87	No	No	0	7	5
1221	R:R:F808	R:R:V802	13.11	Yes	No	0	7	5
1222	R:R:F803	T:T:V238	5.24	No	No	0	7	8
1223	R:R:F804	W:W:?1	24.29	No	Yes	5	9	0
1224	R:R:D811	R:R:K807	2.77	No	No	0	9	6
1225	R:R:F808	R:R:W812	3.01	Yes	No	0	7	5
1226	R:R:D811	R:R:E810	5.2	No	No	0	9	5
1227	R:R:E810	R:R:L814	2.65	No	Yes	0	5	4
1228	R:R:K816	R:R:W812	16.24	No	No	0	4	5
1229	R:R:K813	R:R:K816	7.18	No	No	0	4	4
1230	R:R:K813	R:R:R817	4.95	No	No	0	4	3
1231	R:R:L814	R:R:L815	5.54	Yes	No	0	4	7
1232	R:R:L814	R:R:R817	4.86	Yes	No	0	4	3
1233	R:R:L814	R:R:R818	3.64	Yes	No	0	4	3
1234	R:R:K816	R:R:T820	3	No	No	0	4	1
1235	S:S:C33	S:S:C43	7.28	No	No	25	9	8
1236	S:S:C33	S:S:P52	3.77	No	Yes	25	9	8
1237	S:S:D42	S:S:S34	4.42	No	No	0	9	4
1238	S:S:D36	S:S:D38	6.65	No	No	0	5	6
1239	S:S:D38	S:S:R40	8.34	No	No	0	6	3
1240	S:S:F58	S:S:R39	8.55	No	No	0	6	7
1241	S:S:Q60	S:S:R39	25.7	No	No	0	5	7
1242	S:S:A61	S:S:R40	8.3	No	No	0	4	3
1243	S:S:L55	S:S:V41	11.92	No	No	72	6	7
1244	S:S:T59	S:S:V41	7.93	No	No	72	8	7
1245	S:S:D42	S:S:S44	8.83	No	No	0	9	7
1246	S:S:D42	S:S:D63	10.65	No	No	0	9	9
1247	S:S:C43	S:S:P52	3.77	No	Yes	25	8	8
1248	S:S:C43	S:S:I64	3.27	No	Yes	25	8	6
1249	S:S:M66	S:S:S44	3.07	No	No	0	9	7
1250	S:S:G45	S:S:M66	3.49	No	No	0	8	9
1251	S:S:K46	S:S:L48	2.82	No	No	0	4	8
1252	S:S:L48	S:S:P52	3.28	No	Yes	0	8	8
1253	S:S:L48	S:S:N67	9.61	No	Yes	0	8	9
1254	S:S:N68	S:S:T49	4.39	No	No	0	9	4
1255	S:S:P52	S:S:V51	3.53	Yes	No	0	8	5
1256	S:S:A76	S:S:V51	3.39	No	No	0	4	5
1257	S:S:F77	S:S:V51	5.24	Yes	No	0	7	5
1258	S:S:I64	S:S:P52	3.39	Yes	Yes	25	6	8
1259	S:S:E53	S:S:G54	3.27	No	No	0	2	4
1260	S:S:L55	S:S:T59	8.84	No	No	72	6	8
1261	S:S:F58	S:S:S56	5.28	No	No	0	6	6
1262	S:S:E84	S:S:Q60	21.66	No	No	0	6	5
1263	S:S:A61	S:S:E85	4.53	No	Yes	0	4	8
1264	S:S:I64	S:S:L62	8.56	Yes	No	0	6	5
1265	S:S:L62	S:S:L86	4.15	No	Yes	0	5	8
1266	S:S:D63	S:S:Q87	2.61	No	No	0	9	8
1267	S:S:I64	S:S:N67	7.08	Yes	Yes	25	6	9
1268	S:S:I64	S:S:L88	4.28	Yes	No	0	6	9
1269	S:S:I64	S:S:N91	4.25	Yes	No	25	6	9
1270	S:S:I69	S:S:N67	2.83	No	Yes	25	7	9
1271	S:S:N67	S:S:N91	4.09	Yes	No	25	9	9
1272	S:S:I69	S:S:N91	8.5	No	No	25	7	9
1273	S:S:F95	S:S:Q71	7.03	No	No	0	3	4
1274	S:S:L72	S:S:P73	3.28	No	No	0	7	5
1275	S:S:F77	S:S:L72	4.87	Yes	No	0	7	7
1276	S:S:I96	S:S:L72	8.56	Yes	No	0	9	7
1277	S:S:A76	S:S:P73	5.61	No	No	0	4	5
1278	S:S:D75	S:S:E74	11.69	No	No	45	4	5
1279	S:S:E74	S:S:H97	25.85	No	Yes	45	5	8
1280	S:S:E74	S:S:K99	2.7	No	Yes	45	5	3
1281	S:S:D75	S:S:K99	4.15	No	Yes	45	4	3
1282	S:S:F77	S:S:F80	6.43	Yes	Yes	0	7	7
1283	S:S:F77	S:S:L86	4.87	Yes	Yes	0	7	8
1284	S:S:F80	S:S:N79	21.75	Yes	No	0	7	4
1285	S:S:F82	S:S:P81	4.33	No	No	0	5	5
1286	S:S:E106	S:S:F82	7	No	No	0	7	5
1287	S:S:L104	S:S:L83	4.15	No	No	0	9	9
1288	S:S:E84	S:S:E85	11.42	No	Yes	0	6	8
1289	S:S:E84	S:S:K108	5.4	No	No	0	6	8
1290	S:S:E85	S:S:Q87	3.82	Yes	No	0	8	8
1291	S:S:E85	S:S:V109	4.28	Yes	No	0	8	8
1292	S:S:L86	S:S:L88	5.54	Yes	No	0	8	9
1293	S:S:L110	S:S:L86	4.15	Yes	Yes	0	9	8
1294	S:S:Q87	S:S:T111	7.09	No	No	0	8	9
1295	S:S:L112	S:S:L88	4.15	No	No	0	9	9
1296	S:S:A89	S:S:Q113	6.06	No	Yes	0	9	9
1297	S:S:G90	S:S:N114	3.39	No	Yes	0	9	9
1298	S:S:D92	S:S:Q116	6.53	No	No	0	5	6
1299	S:S:L93	S:S:N115	6.87	No	No	0	9	9
1300	S:S:L117	S:S:L93	2.77	No	No	0	8	9
1301	S:S:F95	S:S:H97	5.66	No	Yes	0	3	8
1302	S:S:I96	S:S:L101	4.28	Yes	No	0	9	7
1303	S:S:A124	S:S:I96	4.87	No	Yes	0	8	9
1304	S:S:H97	S:S:P98	12.2	Yes	No	0	8	4
1305	S:S:H97	S:S:K99	5.24	Yes	Yes	45	8	3
1306	S:S:K99	S:S:S102	4.59	Yes	No	0	3	5
1307	S:S:L107	S:S:L110	2.77	No	Yes	0	9	9
1308	S:S:K108	S:S:Q132	9.49	No	No	0	8	8
1309	S:S:S133	S:S:V109	3.23	No	No	0	9	8
1310	S:S:L110	S:S:L112	6.92	Yes	No	0	9	9
1311	S:S:L110	S:S:L131	5.54	Yes	No	0	9	9
1312	S:S:L110	S:S:L134	4.15	Yes	Yes	0	9	9
1313	S:S:R135	S:S:T111	7.76	Yes	No	0	9	9
1314	S:S:L112	S:S:L136	4.15	No	Yes	0	9	9
1315	S:S:N114	S:S:Q113	2.64	Yes	Yes	6	9	9
1316	S:S:Q113	S:S:R135	5.84	Yes	Yes	6	9	9
1317	S:S:D137	S:S:Q113	10.44	Yes	Yes	6	9	9
1318	S:S:A138	S:S:N114	4.69	No	Yes	6	9	9
1319	S:S:L117	S:S:P121	3.28	No	No	0	8	8
1320	S:S:L117	S:S:N139	6.87	No	No	0	8	9
1321	S:S:H140	S:S:K118	5.24	No	No	0	8	4
1322	S:S:S143	S:S:T119	4.8	No	No	0	3	5
1323	S:S:P145	S:S:T119	3.5	Yes	No	0	9	5
1324	S:S:P121	S:S:V120	3.53	No	Yes	0	8	7
1325	S:S:L136	S:S:V120	2.98	Yes	Yes	14	9	7
1326	S:S:I141	S:S:V120	4.61	Yes	Yes	14	9	7
1327	S:S:V120	S:S:V144	4.81	Yes	Yes	14	7	9
1328	S:S:F149	S:S:V120	2.62	Yes	Yes	0	9	7
1329	S:S:P145	S:S:S122	10.69	Yes	No	0	9	5
1330	S:S:D147	S:S:S122	4.42	No	No	0	3	5
1331	S:S:E123	S:S:R126	8.14	No	No	0	5	4
1332	S:S:D147	S:S:E123	3.9	No	No	0	3	5
1333	S:S:F149	S:S:I125	2.51	Yes	No	0	9	5
1334	S:S:E150	S:S:R126	6.98	No	No	0	4	4
1335	S:S:L128	S:S:L131	2.77	No	No	0	9	9
1336	S:S:L131	S:S:L152	2.77	No	No	0	9	8
1337	S:S:H157	S:S:S133	6.97	Yes	No	0	9	9
1338	S:S:L134	S:S:L136	6.92	Yes	Yes	0	9	9
1339	S:S:F149	S:S:L134	3.65	Yes	Yes	0	9	9
1340	S:S:L134	S:S:L158	4.15	Yes	No	0	9	9
1341	S:S:D137	S:S:R135	16.68	Yes	Yes	6	9	9
1342	S:S:R135	S:S:W159	13	Yes	Yes	6	9	9
1343	S:S:L136	S:S:N139	4.12	Yes	No	14	9	9
1344	S:S:I141	S:S:L136	2.85	Yes	Yes	14	9	9
1345	S:S:L136	S:S:L160	4.15	Yes	No	0	9	9
1346	S:S:D137	S:S:W159	3.35	Yes	Yes	6	9	9
1347	S:S:D137	S:S:D161	11.98	Yes	No	6	9	9
1348	S:S:I141	S:S:N139	7.08	Yes	No	14	9	9
1349	S:S:I141	S:S:N163	8.5	Yes	Yes	14	9	9
1350	S:S:I141	S:S:L165	2.85	Yes	No	14	9	9
1351	S:S:S143	S:S:T142	3.2	No	No	0	3	6
1352	S:S:P145	S:S:V144	3.53	Yes	Yes	14	9	9
1353	S:S:S148	S:S:V144	3.23	No	Yes	14	8	9
1354	S:S:P172	S:S:V144	3.53	No	Yes	0	9	9
1355	S:S:P145	S:S:S148	3.56	Yes	No	14	9	8
1356	S:S:D147	S:S:E150	3.9	No	No	0	3	4
1357	S:S:F149	S:S:S148	10.57	Yes	No	0	9	8
1358	S:S:F149	S:S:L176	3.65	Yes	Yes	0	9	9
1359	S:S:E150	S:S:N175	2.63	No	No	0	4	4
1360	S:S:L152	S:S:L155	4.15	No	No	0	8	9
1361	S:S:Q154	S:S:V153	2.87	No	No	0	8	3
1362	S:S:L155	S:S:L176	4.15	No	Yes	0	9	9
1363	S:S:H157	S:S:R156	10.16	Yes	No	0	9	9
1364	S:S:Q180	S:S:R156	11.68	No	No	0	9	9
1365	S:S:H157	S:S:W159	5.29	Yes	Yes	6	9	9
1366	S:S:A181	S:S:H157	2.93	No	Yes	6	9	9
1367	S:S:L158	S:S:L182	4.15	No	Yes	0	9	8
1368	S:S:D161	S:S:W159	3.35	No	Yes	6	9	9
1369	S:S:L160	S:S:N163	2.75	No	Yes	0	9	9
1370	S:S:L160	S:S:L184	4.15	No	Yes	0	9	9
1371	S:S:D162	S:S:L186	6.79	No	Yes	6	9	9
1372	S:S:L165	S:S:N163	5.49	No	Yes	14	9	9
1373	S:S:N163	S:S:N187	6.81	Yes	No	14	9	9
1374	S:S:L165	S:S:N187	10.98	No	No	14	9	9
1375	S:S:E167	S:S:T166	7.06	No	No	0	6	6
1376	S:S:I192	S:S:V168	3.07	Yes	No	20	8	8
1377	S:S:F197	S:S:V168	3.93	Yes	No	20	9	8
1378	S:S:P169	S:S:P172	5.84	No	No	0	9	9
1379	S:S:L173	S:S:P169	4.93	No	No	0	9	9
1380	S:S:H171	S:S:P172	4.58	No	No	0	1	9
1381	S:S:H171	S:S:S174	4.18	No	No	0	1	5
1382	S:S:L173	S:S:L182	4.15	No	Yes	0	9	8
1383	S:S:L176	S:S:L179	6.92	Yes	No	0	9	9
1384	S:S:P177	S:S:T178	3.5	No	No	0	4	5
1385	S:S:N199	S:S:P177	3.26	No	No	0	9	4
1386	S:S:L179	S:S:L182	2.77	No	Yes	0	9	8
1387	S:S:L179	S:S:L200	5.54	No	No	0	9	9
1388	S:S:Q180	S:S:S202	2.89	No	No	0	9	8
1389	S:S:L182	S:S:L184	6.92	Yes	Yes	0	8	9
1390	S:S:F197	S:S:L182	3.65	Yes	Yes	0	9	8
1391	S:S:L182	S:S:L206	4.15	Yes	Yes	0	8	9
1392	S:S:H207	S:S:T183	9.58	Yes	No	0	9	9
1393	S:S:L184	S:S:N187	4.12	Yes	No	0	9	9
1394	S:S:I189	S:S:L184	2.85	No	Yes	0	9	9
1395	S:S:L184	S:S:L208	4.15	Yes	Yes	0	9	9
1396	S:S:A185	S:S:L186	3.15	No	Yes	0	9	9
1397	S:S:A185	S:S:H209	4.39	No	Yes	0	9	9
1398	S:S:L186	S:S:N210	4.12	Yes	Yes	0	9	9
1399	S:S:K188	S:S:K212	2.87	No	No	0	4	5
1400	S:S:I189	S:S:N211	9.91	No	Yes	0	9	9
1401	S:S:S190	S:S:S191	3.26	No	No	0	3	4
1402	S:S:I192	S:S:P193	3.39	Yes	No	0	8	9
1403	S:S:F197	S:S:I192	2.51	Yes	Yes	20	9	8
1404	S:S:I192	S:S:L216	4.28	Yes	Yes	20	8	6
1405	S:S:C220	S:S:I192	3.27	Yes	Yes	20	5	8
1406	S:S:D194	S:S:F195	3.58	No	Yes	46	8	2
1407	S:S:D194	S:S:S217	8.83	No	No	0	8	6
1408	S:S:D194	S:S:H219	2.52	No	Yes	46	8	5
1409	S:S:F195	S:S:T198	5.19	Yes	No	0	2	4
1410	S:S:F195	S:S:H219	9.05	Yes	Yes	46	2	5
1411	S:S:D222	S:S:F195	5.97	No	Yes	46	4	2
1412	S:S:A196	S:S:F197	2.77	No	Yes	0	9	9
1413	S:S:F197	S:S:L200	3.65	Yes	No	0	9	9
1414	S:S:L200	S:S:L203	5.54	No	Yes	0	9	9
1415	S:S:L203	S:S:L206	2.77	Yes	Yes	0	9	9
1416	S:S:L203	S:S:L224	5.54	Yes	No	73	9	9
1417	S:S:L203	S:S:L227	2.77	Yes	No	73	9	9
1418	S:S:V204	S:S:V205	3.21	Yes	Yes	6	9	9
1419	S:S:E228	S:S:V204	5.7	No	Yes	0	9	9
1420	S:S:H207	S:S:V205	4.15	Yes	Yes	6	9	9
1421	S:S:T229	S:S:V205	9.52	No	Yes	0	9	9
1422	S:S:L206	S:S:L208	5.54	Yes	Yes	0	9	9
1423	S:S:L206	S:S:L230	4.15	Yes	No	0	9	9
1424	S:S:D231	S:S:H207	11.35	No	Yes	0	9	9
1425	S:S:L208	S:S:N211	4.12	Yes	Yes	20	9	9
1426	S:S:I213	S:S:L208	2.85	Yes	Yes	20	9	9
1427	S:S:L208	S:S:L232	4.15	Yes	No	0	9	9
1428	S:S:H209	S:S:N210	3.83	Yes	Yes	0	9	9
1429	S:S:H209	S:S:N233	5.1	Yes	Yes	0	9	9
1430	S:S:N210	S:S:Y234	11.63	Yes	Yes	0	9	6
1431	S:S:I213	S:S:N211	5.66	Yes	Yes	20	9	9
1432	S:S:N211	S:S:N235	2.72	Yes	No	20	9	9
1433	S:S:I213	S:S:L216	4.28	Yes	Yes	20	9	6
1434	S:S:I213	S:S:N235	8.5	Yes	No	20	9	9
1435	S:S:I213	S:S:L237	2.85	Yes	No	0	9	8
1436	S:S:C220	S:S:L216	3.17	Yes	Yes	20	5	6
1437	S:S:L216	S:S:P241	4.93	Yes	No	0	6	9
1438	S:S:H219	S:S:Q218	17.31	Yes	No	0	5	3
1439	S:S:D222	S:S:H219	16.39	No	Yes	46	4	5
1440	S:S:C220	S:S:F221	11.17	Yes	No	0	5	9
1441	S:S:F221	S:S:L230	4.87	No	No	0	9	9
1442	S:S:F221	S:S:L247	3.65	No	Yes	0	9	9
1443	S:S:L224	S:S:L227	6.92	No	No	73	9	9
1444	S:S:D225	S:S:N226	2.69	No	No	0	4	8
1445	S:S:D225	S:S:P248	12.88	No	No	0	4	4
1446	S:S:L227	S:S:L247	5.54	No	Yes	0	9	9
1447	S:S:E228	S:S:K251	5.4	No	Yes	0	9	9
1448	S:S:D231	S:S:T229	2.89	No	No	0	9	9
1449	S:S:L230	S:S:L253	4.15	No	Yes	0	9	9
1450	S:S:D231	S:S:N233	4.04	No	Yes	0	9	9
1451	S:S:N233	S:S:Y234	3.49	Yes	Yes	47	9	6
1452	S:S:H256	S:S:N233	15.31	Yes	Yes	47	9	9
1453	S:S:H256	S:S:Y234	4.36	Yes	Yes	47	9	6
1454	S:S:S257	S:S:Y234	16.53	No	Yes	47	8	6
1455	S:S:L237	S:S:P241	3.28	No	No	0	8	9
1456	S:S:L237	S:S:N258	8.24	No	Yes	0	8	9
1457	S:S:F240	S:S:P241	7.22	Yes	No	0	9	9
1458	S:S:F240	S:S:F255	7.5	Yes	Yes	0	9	9
1459	S:S:F240	S:S:P264	5.78	Yes	No	0	9	9
1460	S:S:A267	S:S:F240	2.77	No	Yes	0	9	9
1461	S:S:F240	S:S:F268	4.29	Yes	Yes	0	9	9
1462	S:S:K245	S:S:Q242	2.71	No	No	0	5	4
1463	S:S:I244	S:S:L253	5.71	No	Yes	0	8	9
1464	S:S:I244	S:S:N271	4.25	No	Yes	0	8	9
1465	S:S:L247	S:S:L250	2.77	Yes	Yes	0	9	9
1466	S:S:L250	S:S:L253	2.77	Yes	Yes	0	9	9
1467	S:S:L250	S:S:N271	4.12	Yes	Yes	15	9	9
1468	S:S:L250	S:S:L274	2.77	Yes	Yes	15	9	9
1469	S:S:E252	S:S:K251	2.7	No	Yes	0	9	9
1470	S:S:K251	S:S:R275	6.19	Yes	Yes	0	9	5
1471	S:S:F255	S:S:L253	7.31	Yes	Yes	0	9	9
1472	S:S:F268	S:S:L253	3.65	Yes	Yes	0	9	9
1473	S:S:F255	S:S:N258	3.62	Yes	Yes	15	9	9
1474	S:S:F255	S:S:I260	5.02	Yes	No	15	9	9
1475	S:S:F255	S:S:I277	2.51	Yes	Yes	15	9	8
1476	S:S:F255	S:S:L279	3.65	Yes	No	15	9	8
1477	S:S:H256	S:S:S257	6.97	Yes	No	47	9	8
1478	S:S:H256	S:S:H278	3.58	Yes	No	0	9	8
1479	S:S:H256	S:S:Y280	26.13	Yes	No	0	9	7
1480	S:S:I260	S:S:N258	8.5	No	Yes	15	9	9
1481	S:S:N258	S:S:N282	2.72	Yes	Yes	15	9	9
1482	S:S:P283	S:S:S259	3.56	No	No	0	9	6
1483	S:S:I260	S:S:N282	7.08	No	Yes	15	9	9
1484	S:S:S261	S:S:V262	4.85	No	No	0	4	5
1485	S:S:F286	S:S:V262	2.62	No	No	0	4	5
1486	S:S:I263	S:S:P264	3.39	No	No	0	9	9
1487	S:S:D265	S:S:G266	3.35	No	No	0	8	4
1488	S:S:D265	S:S:S290	7.36	No	No	0	8	8
1489	S:S:D269	S:S:G266	5.03	No	No	0	3	4
1490	S:S:F268	S:S:N271	3.62	Yes	Yes	15	9	9
1491	S:S:F268	S:S:L274	3.65	Yes	Yes	15	9	9
1492	S:S:F268	S:S:I277	6.28	Yes	Yes	15	9	8
1493	S:S:L274	S:S:N271	4.12	Yes	Yes	15	9	9
1494	S:S:I277	S:S:L274	2.85	Yes	Yes	15	8	9
1495	S:S:L274	S:S:L295	4.15	Yes	No	0	9	9
1496	S:S:R275	S:S:T276	3.88	Yes	No	0	5	8
1497	S:S:D297	S:S:R275	15.48	No	Yes	0	5	5
1498	S:S:H278	S:S:T276	2.74	No	No	0	8	8
1499	S:S:I277	S:S:L279	4.28	Yes	No	15	8	8
1500	S:S:F292	S:S:I277	2.51	Yes	Yes	0	9	8
1501	S:S:D281	S:S:Y280	3.45	No	No	0	8	7
1502	S:S:L284	S:S:N282	2.75	No	Yes	0	8	9
1503	S:S:M308	S:S:S285	4.6	No	No	0	4	8
1504	S:S:F286	S:S:G288	6.02	No	No	0	4	9
1505	S:S:G288	S:S:V287	3.68	No	Yes	0	9	9
1506	S:S:F292	S:S:V287	2.62	Yes	Yes	0	9	9
1507	S:S:I303	S:S:V287	4.61	No	Yes	0	8	9
1508	S:S:V287	S:S:V309	3.21	Yes	Yes	0	9	7
1509	S:S:N289	S:S:S290	5.96	No	No	74	4	8
1510	S:S:N289	S:S:Q311	9.24	No	No	0	4	4
1511	S:S:N289	S:S:N314	6.81	No	No	74	4	7
1512	S:S:N314	S:S:S290	5.96	No	No	74	7	8
1513	S:S:A291	S:S:F292	2.77	No	Yes	0	9	9
1514	S:S:F292	S:S:L301	7.31	Yes	No	0	9	9
1515	S:S:H293	S:S:N294	6.38	No	No	0	7	6
1516	S:S:H293	S:S:T316	2.74	No	No	0	7	5
1517	S:S:L295	S:S:L298	5.54	No	No	0	9	9
1518	S:S:L295	S:S:T318	2.95	No	No	0	9	8
1519	S:S:D297	S:S:S296	8.83	No	No	0	5	9
1520	S:S:L298	S:S:L321	2.77	No	No	0	9	8
1521	S:S:H299	S:S:H320	3.58	No	No	0	7	7
1522	S:S:S300	S:S:S323	3.26	No	No	0	9	7
1523	S:S:I303	S:S:L301	5.71	No	No	0	8	9
1524	S:S:L301	S:S:L324	4.15	No	No	0	9	9
1525	S:S:R304	S:S:V302	3.92	No	No	48	8	7
1526	S:S:T325	S:S:V302	4.76	Yes	No	48	8	7
1527	S:S:R304	S:S:T325	2.59	No	Yes	48	8	8
1528	S:S:R304	S:S:T327	14.23	No	Yes	48	8	9
1529	S:S:A306	S:S:V309	3.39	No	Yes	0	9	7
1530	S:S:M308	S:S:S307	3.07	No	No	0	4	7
1531	S:S:T329	S:S:V309	4.76	Yes	Yes	34	8	7
1532	S:S:I331	S:S:V309	3.07	Yes	Yes	34	8	7
1533	S:S:K330	S:S:Q310	4.07	No	No	0	5	5
1534	S:S:F312	S:S:P313	8.67	No	No	0	8	9
1535	S:S:F312	S:S:I331	2.51	No	Yes	0	8	8
1536	S:S:F312	S:S:P335	11.56	No	No	0	8	8
1537	S:S:L326	S:S:P313	3.28	Yes	No	0	7	9
1538	S:S:N314	S:S:T316	10.24	No	No	0	7	5
1539	S:S:L315	S:S:Q342	2.66	No	Yes	0	9	8
1540	S:S:L321	S:S:T318	4.42	No	No	0	8	8
1541	S:S:H320	S:S:V319	4.15	No	No	0	7	4
1542	S:S:L321	S:S:Q342	9.32	No	Yes	0	8	8
1543	S:S:E322	S:S:M344	6.77	No	No	0	8	4
1544	S:S:E322	S:S:R346	10.47	No	No	0	8	7
1545	S:S:S323	S:S:T347	4.8	No	No	0	7	6
1546	S:S:L324	S:S:L326	5.54	No	Yes	0	9	7
1547	S:S:L324	S:S:L348	4.15	No	No	0	9	9
1548	S:S:T325	S:S:T327	3.14	Yes	Yes	48	8	9
1549	S:S:D349	S:S:T325	7.23	No	Yes	0	8	8
1550	S:S:I331	S:S:L326	4.28	Yes	Yes	0	8	7
1551	S:S:L326	S:S:L350	2.77	Yes	Yes	0	7	9
1552	S:S:G328	S:S:T327	3.64	No	Yes	0	7	9
1553	S:S:S351	S:S:T327	4.8	Yes	Yes	0	9	9
1554	S:S:G328	S:S:T329	3.64	No	Yes	0	7	8
1555	S:S:I331	S:S:T329	6.08	Yes	Yes	34	8	8
1556	S:S:N353	S:S:T329	8.77	Yes	Yes	34	9	8
1557	S:S:K330	S:S:N354	2.8	No	No	0	5	3
1558	S:S:I331	S:S:N353	8.5	Yes	Yes	34	8	9
1559	S:S:I334	S:S:P335	3.39	No	No	0	7	8
1560	S:S:I334	S:S:L350	4.28	No	Yes	0	7	9
1561	S:S:I334	S:S:P359	6.77	No	Yes	0	7	9
1562	S:S:N337	S:S:P335	6.52	No	No	0	3	8
1563	S:S:N337	S:S:Q340	2.64	No	No	0	3	4
1564	S:S:C339	S:S:C364	7.28	No	No	75	9	9
1565	S:S:E341	S:S:Q342	3.82	No	Yes	0	5	8
1566	S:S:L345	S:S:Q342	5.32	No	Yes	0	9	8
1567	S:S:L345	S:S:L367	5.54	No	No	0	9	7
1568	S:S:R346	S:S:T347	2.59	No	No	0	7	6
1569	S:S:E368	S:S:R346	6.98	No	No	0	7	7
1570	S:S:L348	S:S:L350	4.15	No	Yes	0	9	9
1571	S:S:D349	S:S:S351	2.94	No	Yes	0	8	9
1572	S:S:D349	S:S:S371	4.42	No	No	0	8	6
1573	S:S:L350	S:S:N353	5.49	Yes	Yes	0	9	9
1574	S:S:L350	S:S:L372	2.77	Yes	Yes	0	9	8
1575	S:S:S351	S:S:Y352	8.9	Yes	No	0	9	7
1576	S:S:Q373	S:S:S351	2.89	Yes	Yes	0	8	9
1577	S:S:R374	S:S:Y352	23.66	No	No	0	8	7
1578	S:S:I355	S:S:N353	4.25	No	Yes	34	8	9
1579	S:S:N353	S:S:N375	2.72	Yes	No	34	9	9
1580	S:S:N354	S:S:Q376	7.92	No	No	0	3	4
1581	S:S:I355	S:S:N375	11.33	No	No	34	8	9
1582	S:S:I355	S:S:I377	2.94	No	No	0	8	7
1583	S:S:D357	S:S:R356	3.57	No	No	0	3	3
1584	S:S:R356	S:S:Y378	10.29	No	No	0	3	1
1585	S:S:L358	S:S:P359	3.28	No	Yes	0	8	9
1586	S:S:L358	S:S:L372	4.15	No	Yes	0	8	8
1587	S:S:I377	S:S:L358	5.71	No	No	0	7	8
1588	S:S:F361	S:S:P359	4.33	No	Yes	0	6	9
1589	S:S:N362	S:S:S360	4.47	No	No	0	4	7
1590	S:S:F361	S:S:I370	2.51	No	Yes	0	6	7
1591	S:S:N362	S:S:Q386	2.64	No	No	0	4	4
1592	S:S:G363	S:S:H365	3.18	No	No	0	4	3
1593	S:S:G387	S:S:H365	3.18	No	No	0	5	3
1594	S:S:H365	S:S:I389	14.58	No	No	0	3	3
1595	S:S:I370	S:S:L367	5.71	Yes	No	0	7	7
1596	S:S:L367	S:S:L388	6.92	No	No	0	7	8
1597	S:S:E368	S:S:E369	10.15	No	No	0	7	7
1598	S:S:E368	S:S:R392	6.98	No	Yes	0	7	6
1599	S:S:E369	S:S:I393	9.56	No	No	0	7	4
1600	S:S:I370	S:S:L372	4.28	Yes	Yes	0	7	8
1601	S:S:I370	S:S:L391	5.71	Yes	No	0	7	9
1602	S:S:I370	S:S:L394	2.85	Yes	Yes	0	7	7
1603	S:S:Q373	S:S:S371	5.78	Yes	No	0	8	6
1604	S:S:L372	S:S:L396	4.15	Yes	No	0	8	9
1605	S:S:Q373	S:S:R374	8.18	Yes	No	0	8	8
1606	S:S:D395	S:S:Q373	5.22	No	Yes	76	9	8
1607	S:S:Q373	S:S:S397	5.78	Yes	No	76	8	8
1608	S:S:R374	S:S:R398	8.53	No	No	0	8	5
1609	S:S:I377	S:S:N399	9.91	No	No	0	7	9
1610	S:S:Q379	S:S:Y378	11.27	No	No	0	5	1
1611	S:S:K381	S:S:Q379	8.14	No	No	0	1	5
1612	S:S:E403	S:S:Q379	8.92	No	No	0	2	5
1613	S:S:I380	S:S:T384	3.04	No	No	0	7	8
1614	S:S:K381	S:S:T384	3	No	No	0	1	8
1615	S:S:E382	S:S:G383	4.91	No	No	0	4	4
1616	S:S:E382	S:S:H405	12.31	No	No	0	4	6
1617	S:S:F385	S:S:T384	6.49	No	No	0	9	8
1618	S:S:F385	S:S:L394	9.74	No	Yes	0	9	7
1619	S:S:G387	S:S:T411	5.46	No	No	0	5	4
1620	S:S:L388	S:S:L391	5.54	No	No	0	8	9
1621	S:S:I393	S:S:R392	6.26	No	Yes	0	4	6
1622	S:S:R392	S:S:T416	7.76	Yes	No	0	6	4
1623	S:S:L394	S:S:L396	4.15	Yes	No	0	7	9
1624	S:S:L394	S:S:L418	4.15	Yes	Yes	0	7	9
1625	S:S:D395	S:S:S397	5.89	No	No	76	9	8
1626	S:S:D395	S:S:D419	5.32	No	No	0	9	9
1627	S:S:R398	S:S:S397	2.64	No	No	0	5	8
1628	S:S:F422	S:S:R398	11.76	No	No	0	4	5
1629	S:S:I401	S:S:N399	2.83	Yes	No	16	8	9
1630	S:S:N399	S:S:N423	6.81	No	No	16	9	9
1631	S:S:I401	S:S:I404	2.94	Yes	No	16	8	7
1632	S:S:I401	S:S:N423	11.33	Yes	No	16	8	9
1633	S:S:I401	S:S:L425	2.85	Yes	Yes	16	8	9
1634	S:S:E403	S:S:H402	11.08	No	No	0	2	3
1635	S:S:I404	S:S:L425	5.71	No	Yes	16	7	9
1636	S:S:I404	S:S:P429	6.77	No	No	0	7	9
1637	S:S:H405	S:S:S406	2.79	No	Yes	40	6	3
1638	S:S:H405	S:S:R407	4.51	No	Yes	40	6	4
1639	S:S:R407	S:S:S406	2.64	Yes	Yes	40	4	3
1640	S:S:E431	S:S:S406	2.87	No	Yes	40	3	3
1641	S:S:A410	S:S:R407	2.77	No	Yes	40	3	4
1642	S:S:E431	S:S:R407	11.63	No	Yes	40	3	4
1643	S:S:A408	S:S:F409	2.77	No	No	0	8	8
1644	S:S:F409	S:S:L418	6.09	No	Yes	0	8	9
1645	S:S:F409	S:S:L433	10.96	No	No	0	8	9
1646	S:S:A410	S:S:E431	4.53	No	No	40	3	3
1647	S:S:I415	S:S:L412	8.56	No	No	0	7	8
1648	S:S:G413	S:S:P414	4.06	No	No	0	3	5
1649	S:S:I415	S:S:L418	4.28	No	Yes	0	7	9
1650	S:S:I415	S:S:L436	5.71	No	No	0	7	8
1651	S:S:N417	S:S:T416	4.39	No	No	0	7	4
1652	S:S:N437	S:S:T416	4.39	Yes	No	0	5	4
1653	S:S:N417	S:S:Q438	9.24	No	No	0	7	9
1654	S:S:L418	S:S:V420	2.98	Yes	No	0	9	6
1655	S:S:L418	S:S:L439	2.77	Yes	Yes	0	9	8
1656	S:S:D419	S:S:S421	5.89	No	No	0	9	7
1657	S:S:D419	S:S:K440	16.59	No	No	0	9	8
1658	S:S:N423	S:S:V420	5.91	No	No	0	9	6
1659	S:S:L425	S:S:V420	2.98	Yes	No	0	9	6
1660	S:S:F422	S:S:S421	9.25	No	No	0	4	7
1661	S:S:S421	S:S:V442	3.23	No	No	0	7	4
1662	S:S:F422	S:S:G443	4.52	No	No	0	4	8
1663	S:S:E424	S:S:F445	8.16	No	No	0	3	1
1664	S:S:E424	S:S:K446	8.1	No	No	0	3	3
1665	S:S:L425	S:S:N444	5.49	Yes	No	16	9	9
1666	S:S:K446	S:S:T426	4.5	No	No	0	3	4
1667	S:S:E449	S:S:S427	2.87	No	No	0	4	4
1668	S:S:F428	S:S:P429	2.89	Yes	No	0	4	9
1669	S:S:F428	S:S:T430	2.59	Yes	No	0	4	5
1670	S:S:F428	S:S:L439	7.31	Yes	Yes	16	4	8
1671	S:S:F428	S:S:L441	3.65	Yes	Yes	16	4	8
1672	S:S:F428	S:S:L451	3.65	Yes	No	0	4	7
1673	S:S:D455	S:S:T430	8.67	No	No	0	4	5
1674	S:S:F456	S:S:T430	5.19	No	No	0	5	5
1675	S:S:L433	S:S:L436	9.69	No	No	0	9	8
1676	S:S:N434	S:S:V457	7.39	No	No	0	3	4
1677	S:S:L436	S:S:L439	2.77	No	Yes	0	8	8
1678	S:S:N437	S:S:N458	2.72	Yes	Yes	7	5	4
1679	S:S:N437	S:S:R460	4.82	Yes	No	7	5	9
1680	S:S:Q438	S:S:S461	8.66	No	No	0	9	6
1681	S:S:Q438	T:T:K177	10.85	No	No	0	9	9
1682	S:S:L439	S:S:L441	6.92	Yes	Yes	16	8	8
1683	S:S:L439	S:S:L462	4.15	Yes	Yes	0	8	7
1684	S:S:K440	S:S:S463	9.18	No	No	0	8	8
1685	S:S:L441	S:S:N444	2.75	Yes	No	16	8	9
1686	S:S:L441	S:S:L447	2.77	Yes	No	16	8	7
1687	S:S:G443	S:S:V442	3.68	No	No	0	8	4
1688	S:S:S463	S:S:V442	3.23	No	No	0	8	4
1689	S:S:L447	S:S:N444	2.75	No	No	16	7	9
1690	S:S:K448	S:S:Y466	7.17	No	No	0	7	6
1691	S:S:K448	S:S:T614	4.5	No	No	0	7	4
1692	S:S:A450	S:S:Q469	3.03	No	No	0	4	9
1693	S:S:F456	S:S:L451	3.65	No	No	0	5	7
1694	S:S:A452	S:S:K454	3.21	No	No	77	3	5
1695	S:S:A452	S:S:D455	6.18	No	No	77	3	4
1696	S:S:A453	S:S:F473	4.16	No	No	0	4	8
1697	S:S:D455	S:S:K454	6.91	No	No	77	4	5
1698	S:S:F456	S:S:L459	6.09	No	No	0	5	7
1699	S:S:I518	S:S:N458	2.83	No	Yes	0	4	4
1700	S:S:L459	S:S:L462	5.54	No	Yes	0	7	7
1701	S:S:L462	S:S:V464	4.47	Yes	No	0	7	7
1702	S:S:F473	S:S:L462	3.65	No	Yes	0	8	7
1703	S:S:S463	S:S:T523	7.99	No	No	0	8	6
1704	S:S:P465	S:S:V464	3.53	No	No	78	9	7
1705	S:S:Q469	S:S:V464	5.73	No	No	78	9	7
1706	S:S:P465	S:S:Y466	4.17	No	No	0	9	6
1707	S:S:P465	S:S:Q469	3.16	No	No	78	9	9
1708	S:S:K530	S:S:Y468	19.11	No	Yes	21	8	9
1709	S:S:I610	S:S:Y468	3.63	No	Yes	0	7	9
1710	S:S:E613	S:S:Y468	12.35	Yes	Yes	21	9	9
1711	S:S:P691	S:S:Y468	4.17	Yes	Yes	21	9	9
1712	S:S:C470	S:S:C522	7.28	No	No	0	9	9
1713	S:S:C470	S:S:T526	5.07	No	No	0	9	8
1714	S:S:C471	S:S:T526	5.07	No	No	0	9	8
1715	S:S:C471	S:S:C532	7.28	No	No	35	9	9
1716	S:S:F473	S:S:I520	3.77	No	No	0	8	5
1717	S:S:H521	S:S:I519	6.63	No	Yes	0	8	4
1718	S:S:P524	S:S:T523	5.25	No	No	0	9	6
1719	S:S:A528	S:S:E780	4.53	No	No	0	9	8
1720	S:S:F529	S:S:P779	7.22	No	No	0	8	8
1721	S:S:F529	S:S:M782	6.22	No	No	0	8	5
1722	S:S:E613	S:S:K530	2.7	Yes	No	21	9	8
1723	S:S:F605	S:S:P531	10.11	Yes	No	21	9	8
1724	S:S:P531	S:S:P691	3.9	No	Yes	21	8	9
1725	S:S:C532	S:S:E533	3.04	No	No	35	9	4
1726	S:S:E533	S:S:Y534	7.86	No	No	35	4	4
1727	S:S:E533	S:S:G603	6.55	No	No	35	4	9
1728	S:S:W602	S:S:Y534	10.61	No	No	0	4	4
1729	S:S:G603	S:S:Y534	2.9	No	No	35	9	4
1730	S:S:L535	S:S:L536	4.15	Yes	Yes	21	9	5
1731	S:S:D598	S:S:L535	6.79	No	Yes	21	9	9
1732	S:S:F605	S:S:L535	10.96	Yes	Yes	21	9	9
1733	S:S:L535	S:S:P691	3.28	Yes	Yes	21	9	9
1734	S:S:L536	S:S:V545	5.96	Yes	No	0	5	8
1735	S:S:D598	S:S:L536	4.07	No	Yes	21	9	5
1736	S:S:L536	S:S:L787	4.15	Yes	No	0	5	9
1737	S:S:R542	S:S:W539	8	No	No	0	9	9
1738	S:S:I541	S:S:T544	3.04	No	No	0	7	9
1739	S:S:I541	S:S:I788	2.94	No	No	0	7	7
1740	S:S:T595	S:S:V545	3.17	Yes	No	0	7	8
1741	S:S:T595	S:S:W546	7.28	Yes	No	0	7	9
1742	S:S:F547	S:S:V551	3.93	No	No	0	4	6
1743	S:S:I548	S:S:P791	3.39	No	No	0	7	9
1744	S:S:I548	S:S:L792	2.85	No	No	0	7	9
1745	S:S:C795	S:S:I548	6.55	No	No	0	9	7
1746	S:S:F549	S:S:L553	3.65	Yes	No	0	5	5
1747	S:S:F549	S:S:T591	3.89	Yes	No	0	5	7
1748	S:S:F549	S:S:G592	7.53	Yes	No	79	5	5
1749	S:S:F549	S:S:T595	2.59	Yes	Yes	79	5	7
1750	S:S:A552	S:S:C795	3.61	No	No	0	8	9
1751	S:S:F555	S:S:P798	2.89	No	Yes	0	5	9
1752	S:S:F555	S:S:V799	3.93	No	No	0	5	9
1753	S:S:N556	S:S:S581	2.98	Yes	No	0	9	7
1754	S:S:N556	S:S:N584	6.81	Yes	Yes	36	9	9
1755	S:S:L585	S:S:N556	2.75	No	Yes	0	4	9
1756	S:S:N556	S:S:P798	6.52	Yes	Yes	36	9	9
1757	S:S:L557	S:S:L558	2.77	No	No	0	3	7
1758	S:S:T562	S:S:V559	3.17	No	No	0	5	8
1759	S:S:S581	S:S:V559	8.08	No	No	0	7	8
1760	S:S:V559	S:S:Y801	3.79	No	Yes	0	8	9
1761	S:S:I560	S:S:S581	3.1	No	No	0	4	7
1762	S:S:I560	S:S:V582	4.61	No	No	0	4	3
1763	S:S:L561	S:S:L815	8.3	No	No	0	4	7
1764	S:S:D811	S:S:T562	5.78	Yes	No	0	9	5
1765	S:S:F564	S:S:T563	2.59	No	No	0	8	4
1766	S:S:C566	S:S:T568	3.38	No	No	0	5	2
1767	S:S:S569	S:S:T568	3.2	No	No	0	3	2
1768	S:S:P571	S:S:S573	3.56	No	No	81	7	5
1769	S:S:K574	S:S:P571	10.04	No	No	81	7	7
1770	S:S:F576	S:S:S572	3.96	Yes	No	26	6	6
1771	S:S:E642	S:S:S572	8.62	Yes	No	26	8	6
1772	S:S:F662	S:S:S572	7.93	No	No	26	4	6
1773	S:S:K574	S:S:S573	3.06	No	No	81	7	5
1774	S:S:M745	S:S:S573	4.6	No	No	0	7	5
1775	S:S:D811	S:S:K574	4.15	Yes	No	0	9	7
1776	S:S:L575	S:S:L579	6.92	No	No	0	6	7
1777	S:S:A639	S:S:F576	4.16	No	Yes	0	9	6
1778	S:S:E642	S:S:F576	5.83	Yes	Yes	26	8	6
1779	S:S:I577	S:S:Y801	7.25	No	Yes	0	5	9
1780	S:S:L579	S:S:L635	4.15	No	No	0	7	5
1781	S:S:F670	S:S:L579	4.87	No	No	0	3	7
1782	S:S:I580	S:S:S583	3.1	Yes	No	36	7	5
1783	S:S:I580	S:S:N584	4.25	Yes	Yes	36	7	9
1784	S:S:I580	S:S:L635	2.85	Yes	No	0	7	5
1785	S:S:I580	S:S:L636	2.85	Yes	No	0	7	9
1786	S:S:I580	S:S:N797	4.25	Yes	Yes	36	7	9
1787	S:S:N584	S:S:S583	4.47	Yes	No	36	9	5
1788	S:S:S583	S:S:S631	4.89	No	No	0	5	5
1789	S:S:A794	S:S:N584	4.69	No	Yes	0	8	9
1790	S:S:N584	S:S:N797	6.81	Yes	Yes	36	9	9
1791	S:S:N584	S:S:P798	3.26	Yes	Yes	36	9	9
1792	S:S:F586	S:S:F627	5.36	No	Yes	0	6	5
1793	S:S:F586	S:S:S628	2.64	No	No	0	6	8
1794	S:S:M587	S:S:S628	10.73	No	No	0	6	8
1795	S:S:F790	S:S:M587	6.22	Yes	No	0	5	6
1796	S:S:A794	S:S:M587	4.83	No	No	0	8	6
1797	S:S:G588	S:S:T591	3.64	No	No	0	9	7
1798	S:S:L594	S:S:Y590	14.07	No	Yes	0	9	5
1799	S:S:A621	S:S:Y590	2.67	No	Yes	0	5	5
1800	S:S:A625	S:S:Y590	5.34	No	Yes	0	7	5
1801	S:S:L694	S:S:Y590	8.21	Yes	Yes	0	7	5
1802	S:S:G592	S:S:T595	3.64	No	Yes	79	5	7
1803	S:S:F596	S:S:T595	2.59	No	Yes	0	4	7
1804	S:S:L597	S:S:W612	9.11	No	Yes	0	8	9
1805	S:S:F605	S:S:S601	2.64	Yes	No	0	9	9
1806	S:S:F608	S:S:S601	5.28	No	No	0	4	9
1807	S:S:E607	S:S:R604	4.65	No	No	0	1	4
1808	S:S:F605	S:S:P691	2.89	Yes	Yes	21	9	9
1809	S:S:E607	S:S:F608	11.66	No	No	0	1	4
1810	S:S:G617	S:S:W612	2.81	No	Yes	0	7	9
1811	S:S:A621	S:S:W612	2.59	No	Yes	0	5	9
1812	S:S:C693	S:S:W612	6.53	No	Yes	0	9	9
1813	S:S:C618	S:S:E613	3.04	No	Yes	0	9	9
1814	S:S:E613	S:S:P691	3.14	Yes	Yes	21	9	9
1815	S:S:G617	S:S:V620	3.68	No	No	0	7	3
1816	S:S:C618	S:S:C693	7.28	No	No	0	9	9
1817	S:S:K619	S:S:R684	4.95	No	No	82	4	3
1818	S:S:K619	S:S:Y687	3.58	No	Yes	82	4	5
1819	S:S:F623	S:S:T674	6.49	Yes	No	0	4	3
1820	S:S:F623	S:S:G677	3.01	Yes	No	0	4	8
1821	S:S:C678	S:S:F623	5.59	No	Yes	0	4	4
1822	S:S:G677	S:S:V626	3.68	No	No	0	8	6
1823	S:S:F627	S:S:F670	6.43	Yes	No	0	5	3
1824	S:S:A673	S:S:F627	2.77	No	Yes	0	8	5
1825	S:S:F627	S:S:T674	7.78	Yes	No	0	5	3
1826	S:S:E630	S:S:S629	7.19	Yes	No	0	8	8
1827	S:S:F790	S:S:S629	3.96	Yes	No	0	5	8
1828	S:S:E630	S:S:F634	5.83	Yes	Yes	83	8	7
1829	S:S:A673	S:S:E630	3.02	No	Yes	83	8	8
1830	S:S:E630	S:S:L713	2.65	Yes	No	0	8	5
1831	S:S:E630	S:S:N714	11.83	Yes	Yes	0	8	9
1832	S:S:L635	S:S:S631	3	No	No	0	5	5
1833	S:S:F634	S:S:I633	3.77	Yes	Yes	0	7	6
1834	S:S:I633	S:S:N714	4.25	Yes	Yes	0	6	9
1835	S:S:F718	S:S:I633	3.77	Yes	Yes	0	6	6
1836	S:S:A669	S:S:F634	4.16	No	Yes	0	7	7
1837	S:S:A673	S:S:F634	2.77	No	Yes	83	8	7
1838	S:S:I753	S:S:L636	4.28	No	No	0	9	9
1839	S:S:L636	S:S:N756	5.49	No	Yes	0	9	9
1840	S:S:L638	S:S:M637	2.83	No	No	0	7	5
1841	S:S:M721	S:S:T640	6.02	No	No	84	7	7
1842	S:S:I724	S:S:T640	7.6	No	No	0	6	7
1843	S:S:I753	S:S:T640	3.04	No	No	84	9	7
1844	S:S:S644	S:S:V641	3.23	No	No	0	6	6
1845	S:S:E642	S:S:R643	8.14	Yes	Yes	26	8	8
1846	S:S:E642	S:S:S646	5.75	Yes	No	26	8	6
1847	S:S:E642	S:S:F662	5.83	Yes	No	26	8	4
1848	S:S:R643	S:S:S646	5.27	Yes	No	26	8	6
1849	S:S:Q742	S:S:R643	7.01	No	Yes	26	7	8
1850	S:S:I746	S:S:R643	5.01	No	Yes	0	7	8
1851	S:S:R643	S:S:V749	6.54	Yes	No	0	8	7
1852	S:S:I724	S:S:S644	3.1	No	No	0	6	6
1853	S:S:H658	S:S:L645	3.86	No	No	0	4	2
1854	S:S:Q742	S:S:S646	4.33	No	No	26	7	6
1855	S:S:H658	S:S:N657	6.38	No	No	0	4	3
1856	S:S:K660	S:S:L659	8.46	No	No	0	1	1
1857	S:S:C678	S:S:L681	3.17	No	No	0	4	6
1858	S:S:F679	S:S:P680	4.33	No	No	85	5	7
1859	S:S:F679	S:S:F706	4.29	No	Yes	85	5	5
1860	S:S:E686	S:S:P680	4.72	Yes	No	0	4	7
1861	S:S:F706	S:S:P680	14.45	Yes	No	85	5	7
1862	S:S:E686	S:S:H683	8.62	Yes	No	0	4	4
1863	S:S:R684	S:S:Y687	8.23	No	Yes	82	3	5
1864	S:S:E686	S:S:Y687	7.86	Yes	Yes	0	4	5
1865	S:S:E686	S:S:S703	4.31	Yes	No	0	4	5
1866	S:S:S688	S:S:Y687	2.54	No	Yes	0	5	5
1867	S:S:A689	S:S:T698	3.36	No	No	0	4	4
1868	S:S:L692	S:S:L694	2.77	No	Yes	49	7	7
1869	S:S:L692	S:S:P697	3.28	No	Yes	49	7	7
1870	S:S:L692	S:S:L787	2.77	No	No	0	7	9
1871	S:S:F696	S:S:L694	6.09	No	Yes	49	7	7
1872	S:S:L694	S:S:P697	3.28	Yes	Yes	49	7	7
1873	S:S:F696	S:S:P695	4.33	No	No	0	7	9
1874	S:S:F706	S:S:P695	5.78	Yes	No	0	5	9
1875	S:S:F696	S:S:P697	11.56	No	Yes	49	7	7
1876	S:S:P702	S:S:T698	12.24	No	No	0	5	4
1877	S:S:E700	S:S:P770	9.43	No	No	0	3	9
1878	S:S:E700	S:S:L771	14.58	No	No	0	3	7
1879	S:S:P702	S:S:T701	6.99	No	No	0	5	4
1880	S:S:F706	S:S:S703	3.96	Yes	No	0	5	5
1881	S:S:S703	S:S:T707	4.8	No	No	0	5	5
1882	S:S:L710	S:S:N714	2.75	No	Yes	0	9	9
1883	S:S:S767	S:S:V711	3.23	No	No	86	8	9
1884	S:S:F768	S:S:V711	2.62	No	No	86	5	9
1885	S:S:F760	S:S:N714	6.04	Yes	Yes	0	8	9
1886	S:S:F718	S:S:M721	3.73	Yes	No	0	6	7
1887	S:S:F718	S:S:F760	3.22	Yes	Yes	0	6	8
1888	S:S:I753	S:S:M721	7.29	No	No	84	9	7
1889	S:S:I724	S:S:V723	3.07	No	No	0	6	3
1890	S:S:L728	S:S:Y725	5.86	No	Yes	0	9	8
1891	S:S:Y725	S:S:Y729	8.94	Yes	No	0	8	9
1892	S:S:I746	S:S:Y725	3.63	No	Yes	0	7	8
1893	S:S:A750	S:S:Y725	5.34	No	Yes	0	9	8
1894	S:S:Y729	T:T:K239	13.14	No	Yes	0	9	9
1895	S:S:L732	T:T:K243	8.46	No	No	0	7	9
1896	S:S:K807	S:S:S744	4.59	No	No	0	6	5
1897	S:S:M745	S:S:V749	3.04	No	No	0	7	7
1898	S:S:K807	S:S:M745	11.52	No	No	0	6	7
1899	S:S:K747	S:S:W751	4.64	No	Yes	0	7	8
1900	S:S:H748	S:S:L752	14.14	No	No	0	9	9
1901	S:S:H748	S:S:Y801	8.71	No	Yes	80	9	9
1902	S:S:H748	S:S:N805	14.03	No	Yes	80	9	8
1903	S:S:F804	S:S:W751	8.02	No	Yes	5	9	8
1904	S:S:W751	T:T:L236	5.69	Yes	Yes	5	8	9
1905	S:S:W751	T:T:I240	5.87	Yes	No	5	8	9
1906	S:S:W751	X:X:?1	12.49	Yes	Yes	5	8	0
1907	S:S:L752	S:S:N797	4.12	No	Yes	0	9	9
1908	S:S:F754	S:S:I758	6.28	No	No	5	8	7
1909	S:S:F754	T:T:V232	2.62	No	No	5	8	9
1910	S:S:F754	T:T:L236	12.18	No	Yes	5	8	9
1911	S:S:N756	S:S:T755	2.92	Yes	No	0	9	7
1912	S:S:L796	S:S:T755	8.84	No	No	0	8	7
1913	S:S:N756	S:S:P793	4.89	Yes	No	0	9	9
1914	S:S:N756	S:S:N797	2.72	Yes	Yes	0	9	9
1915	S:S:F759	S:S:I758	5.02	No	No	0	9	7
1916	S:S:I758	T:T:V232	3.07	No	No	5	7	9
1917	S:S:F759	S:S:L792	6.09	No	No	0	9	9
1918	S:S:F759	S:S:P793	7.22	No	No	0	9	9
1919	S:S:A764	S:S:F760	5.55	No	Yes	0	9	8
1920	S:S:C761	S:S:P762	3.77	No	No	0	7	9
1921	S:S:F789	S:S:P762	5.78	Yes	No	0	7	9
1922	S:S:F765	S:S:F766	7.5	No	Yes	0	8	9
1923	S:S:F766	S:S:I777	5.02	Yes	No	0	9	6
1924	S:S:F766	S:S:V785	7.87	Yes	No	0	9	7
1925	S:S:F766	T:T:I221	2.51	Yes	No	0	9	9
1926	S:S:F768	S:S:S767	5.28	No	No	86	5	8
1927	S:S:F768	S:S:L771	10.96	No	No	0	5	7
1928	S:S:A769	S:S:I777	4.87	No	No	0	8	6
1929	S:S:M782	S:S:P770	5.03	No	No	0	5	9
1930	S:S:I772	S:S:L771	4.28	No	No	0	8	7
1931	S:S:I772	S:S:I775	2.94	No	No	0	8	4
1932	S:S:I777	S:S:I781	2.94	No	Yes	0	6	8
1933	S:S:P779	S:S:S778	3.56	No	Yes	0	8	6
1934	S:S:I781	S:S:S778	3.1	Yes	Yes	0	8	6
1935	S:S:I781	S:S:S784	3.1	Yes	No	0	8	7
1936	S:S:I781	T:T:F222	6.28	Yes	Yes	9	8	9
1937	S:S:F789	S:S:V785	5.24	Yes	No	0	7	7
1938	S:S:F790	S:S:P791	4.33	Yes	No	0	5	9
1939	S:S:L796	S:S:N797	5.49	No	Yes	0	8	9
1940	S:S:L796	S:S:L800	2.77	No	No	0	8	9
1941	S:S:N797	S:S:P798	3.26	Yes	Yes	36	9	9
1942	S:S:F803	S:S:V799	2.62	No	No	0	7	9
1943	S:S:F804	S:S:L800	6.09	No	No	0	9	9
1944	S:S:N805	S:S:Y801	9.3	Yes	Yes	80	8	9
1945	S:S:F808	S:S:Y801	4.13	Yes	Yes	0	7	9
1946	S:S:F808	S:S:V802	15.73	Yes	No	0	7	5
1947	S:S:F804	X:X:?1	31.58	No	Yes	5	9	0
1948	S:S:N805	S:S:P806	4.89	Yes	No	0	8	9
1949	S:S:K807	S:S:N805	9.79	No	Yes	0	6	8
1950	S:S:F808	S:S:W812	10.02	Yes	No	0	7	5
1951	S:S:D811	S:S:E810	7.8	Yes	No	0	9	5
1952	S:S:D811	S:S:L814	4.07	Yes	No	0	9	4
1953	S:S:K813	S:S:W812	4.64	No	No	87	4	5
1954	S:S:K816	S:S:W812	8.12	No	No	87	4	5
1955	S:S:K813	S:S:K816	7.18	No	No	87	4	4
1956	S:S:K813	S:S:R817	4.95	No	No	0	4	3
1957	S:S:L814	S:S:R817	3.64	No	No	0	4	3
1958	T:T:E57	T:T:F85	3.5	No	Yes	37	8	8
1959	T:T:E57	T:T:T91	7.06	No	No	37	8	8
1960	T:T:E57	T:T:H207	9.85	No	No	37	8	9
1961	T:T:F60	T:T:T58	5.19	No	No	0	8	8
1962	T:T:R84	T:T:T58	6.47	No	No	0	8	8
1963	T:T:A59	T:T:F85	5.55	No	Yes	37	9	8
1964	T:T:A59	T:T:V181	3.39	No	No	37	9	9
1965	T:T:L81	T:T:V61	5.96	No	No	0	8	9
1966	T:T:I205	T:T:V61	3.07	No	No	0	9	9
1967	T:T:E62	T:T:T78	2.82	No	Yes	0	9	9
1968	T:T:E62	T:T:R204	12.79	No	Yes	0	9	9
1969	T:T:I194	T:T:V63	3.07	No	No	0	9	9
1970	T:T:T76	T:T:V64	3.17	No	Yes	29	9	9
1971	T:T:T78	T:T:V64	3.17	Yes	Yes	0	9	9
1972	T:T:R202	T:T:V64	5.23	Yes	Yes	29	9	9
1973	T:T:R204	T:T:V64	6.54	Yes	Yes	29	9	9
1974	T:T:L65	T:T:Q198	7.99	No	No	0	9	9
1975	T:T:E67	T:T:T75	4.23	No	No	65	9	8
1976	T:T:T79	T:T:Y77	4.99	No	Yes	0	9	6
1977	T:T:K190	T:T:T79	3	No	No	0	9	9
1978	T:T:K190	T:T:L81	7.05	No	No	0	9	8
1979	T:T:G83	T:T:T82	3.64	No	No	0	8	8
1980	T:T:D187	T:T:T82	2.89	No	No	0	9	8
1981	T:T:R84	T:T:Y182	7.2	No	Yes	0	8	9
1982	T:T:F85	T:T:T91	18.16	Yes	No	37	8	8
1983	T:T:F85	T:T:V181	2.62	Yes	No	37	8	9
1984	T:T:F85	T:T:H207	4.53	Yes	No	37	8	9
1985	T:T:L168	T:T:S86	7.51	No	No	0	9	9
1986	T:T:N169	T:T:S86	4.47	No	No	0	9	9
1987	T:T:S86	T:T:Y182	5.09	No	Yes	0	9	9
1988	T:T:R87	T:T:S172	13.18	No	No	0	5	5
1989	T:T:A88	T:T:L168	3.15	No	No	0	9	9
1990	T:T:H207	T:T:T91	6.85	No	No	37	9	8
1991	T:T:L92	T:T:P179	3.28	No	Yes	0	7	9
1992	T:T:A94	T:T:R178	2.77	No	Yes	0	9	9
1993	T:T:A94	T:T:I205	3.25	No	No	0	9	9
1994	T:T:E95	T:T:R202	15.12	Yes	Yes	0	8	9
1995	T:T:E95	T:T:R204	19.77	Yes	Yes	0	8	9
1996	T:T:G96	T:T:R202	3	No	Yes	0	8	9
1997	T:T:A201	T:T:I98	4.87	No	No	53	9	8
1998	T:T:A203	T:T:I98	3.25	No	No	0	9	8
1999	T:T:M101	T:T:V99	3.04	Yes	Yes	7	9	7
2000	T:T:V99	T:T:Y116	2.52	Yes	Yes	7	7	9
2001	T:T:V99	T:T:W120	12.26	Yes	Yes	7	7	9
2002	T:T:Q100	T:T:V195	2.87	No	No	0	7	9
2003	T:T:L106	T:T:M101	4.24	No	Yes	0	9	9
2004	T:T:M101	T:T:Y116	5.99	Yes	Yes	7	9	9
2005	T:T:M101	T:T:W120	6.98	Yes	Yes	7	9	9
2006	T:T:H102	T:T:P103	10.68	Yes	No	4	9	9
2007	T:T:H102	T:T:L104	7.71	Yes	Yes	4	9	9
2008	T:T:P103	T:T:V124	3.53	No	No	0	9	9
2009	T:T:K142	T:T:L106	4.23	No	No	0	7	9
2010	T:T:C107	T:T:C136	7.28	No	No	89	9	9
2011	T:T:L137	T:T:N108	4.12	No	No	0	9	9
2012	T:T:N108	T:T:R145	4.82	No	Yes	0	9	9
2013	T:T:E113	T:T:N110	19.72	No	No	0	9	9
2014	T:T:N110	T:T:R145	3.62	No	Yes	0	9	9
2015	T:T:E113	T:T:R149	9.3	No	No	0	9	9
2016	T:T:D114	T:T:Y116	4.6	No	Yes	0	9	9
2017	T:T:W120	T:T:Y116	2.89	Yes	Yes	7	9	9
2018	T:T:G119	T:T:Y118	2.9	Yes	Yes	7	9	9
2019	T:T:G119	T:T:W120	2.81	Yes	Yes	7	9	9
2020	T:T:G119	T:T:T152	3.64	Yes	No	0	9	9
2021	T:T:G122	T:T:W120	2.81	No	Yes	0	9	9
2022	T:T:A151	T:T:W120	10.37	No	Yes	0	9	9
2023	T:T:I155	T:T:V121	4.61	No	No	0	9	9
2024	T:T:A203	T:T:V121	5.09	No	No	0	9	9
2025	T:T:M192	T:T:V123	3.04	Yes	No	0	9	9
2026	T:T:F156	T:T:V124	5.24	Yes	No	0	9	9
2027	T:T:D157	T:T:K125	8.3	Yes	Yes	4	9	9
2028	T:T:K125	T:T:M192	4.32	Yes	Yes	4	9	9
2029	T:T:F156	T:T:L126	4.87	Yes	No	0	9	9
2030	T:T:E127	T:T:Q128	5.1	Yes	Yes	4	9	9
2031	T:T:E127	T:T:L131	2.65	Yes	Yes	4	9	9
2032	T:T:E130	T:T:Q128	7.65	No	Yes	0	6	9
2033	T:T:L131	T:T:Q128	3.99	Yes	Yes	4	9	9
2034	T:T:E160	T:T:Q128	7.65	No	Yes	0	9	9
2035	T:T:E130	T:T:P129	6.29	No	No	0	6	9
2036	T:T:N161	T:T:P129	6.52	No	No	0	9	9
2037	T:T:D132	T:T:L131	4.07	No	Yes	0	9	9
2038	T:T:D132	T:T:P135	3.22	No	No	0	9	9
2039	T:T:C136	T:T:L137	3.17	No	No	0	9	9
2040	T:T:F156	T:T:V139	2.62	Yes	Yes	0	9	9
2041	T:T:A164	T:T:V139	3.39	No	Yes	0	9	9
2042	T:T:L168	T:T:V139	2.98	No	Yes	0	9	9
2043	T:T:A143	T:T:F156	2.77	No	Yes	0	9	9
2044	T:T:K144	T:T:Q148	2.71	No	No	0	9	9
2045	T:T:D174	T:T:K144	2.77	No	No	0	9	9
2046	T:T:R145	T:T:R149	11.73	Yes	No	0	9	9
2047	T:T:A146	T:T:V154	3.39	No	No	0	9	9
2048	T:T:L176	T:T:V147	2.98	No	No	0	9	9
2049	T:T:R178	T:T:V147	2.62	Yes	No	0	9	9
2050	T:T:R178	T:T:T152	9.06	Yes	No	0	9	9
2051	T:T:F156	T:T:V154	2.62	Yes	No	0	9	9
2052	T:T:F156	T:T:V180	2.62	Yes	No	0	9	9
2053	T:T:D157	T:T:S159	7.36	Yes	No	0	9	9
2054	T:T:A188	T:T:D157	4.63	No	Yes	0	9	9
2055	T:T:D157	T:T:M192	6.93	Yes	Yes	4	9	9
2056	T:T:A164	T:T:V158	3.39	No	No	0	9	9
2057	T:T:I165	T:T:V158	4.61	Yes	No	88	9	9
2058	T:T:V158	T:T:Y182	5.05	No	Yes	88	9	9
2059	T:T:E163	T:T:N161	6.57	No	No	0	8	9
2060	T:T:A164	T:T:N161	3.13	No	No	0	9	9
2061	T:T:E163	T:T:P162	7.86	No	No	0	8	7
2062	T:T:I165	T:T:N169	2.83	Yes	No	0	9	9
2063	T:T:I165	T:T:Y182	10.88	Yes	Yes	88	9	9
2064	T:T:G171	T:T:Q170	4.93	No	No	0	5	8
2065	T:T:E173	T:T:G171	4.91	No	No	0	9	5
2066	T:T:P179	T:T:R178	5.76	Yes	Yes	0	9	9
2067	T:T:I205	T:T:P179	3.39	No	Yes	0	9	9
2068	T:T:K184	T:T:Y182	5.97	No	Yes	0	9	9
2069	T:T:A188	T:T:V183	3.39	No	No	0	9	9
2070	T:T:I194	T:T:Q198	2.74	No	No	0	9	9
2071	T:T:K197	T:T:N196	12.59	No	No	0	9	9
2072	T:T:K197	T:T:Q198	4.07	No	No	0	9	9
2073	T:T:K199	T:T:V200	3.04	No	No	0	9	9
2074	T:T:P210	T:T:R208	15.85	No	No	0	9	9
2075	T:T:D218	T:T:Q212	16.97	Yes	Yes	9	9	8
2076	T:T:D218	T:T:E215	10.39	Yes	Yes	9	9	9
2077	T:T:M219	T:T:Y216	4.79	Yes	No	9	9	9
2078	T:T:D218	T:T:M219	2.77	Yes	Yes	9	9	9
2079	T:T:L223	T:T:M219	4.24	Yes	Yes	9	9	9
2080	T:T:F222	T:T:I221	2.51	Yes	No	0	9	9
2081	T:T:F225	T:T:I221	7.54	No	No	0	9	9
2082	T:T:F226	T:T:S230	7.93	Yes	No	5	9	9
2083	T:T:F226	W:W:?1	6.07	Yes	Yes	5	9	0
2084	T:T:L231	T:T:V227	2.98	No	No	0	9	9
2085	T:T:S230	W:W:?1	2.99	No	Yes	5	9	0
2086	T:T:C233	X:X:?1	9.5	No	Yes	0	8	0
2087	T:T:L234	W:W:?1	5.52	No	Yes	0	9	0
2088	T:T:K239	T:T:L236	2.82	Yes	Yes	5	9	9
2089	T:T:I240	T:T:L236	2.85	No	Yes	5	9	9
2090	T:T:K241	T:T:L237	4.23	No	No	0	9	9
2091	T:T:L237	W:W:?1	4.14	No	Yes	5	9	0
2092	T:T:L237	X:X:?1	4.14	No	Yes	5	9	0
2093	T:T:K239	T:T:L242	2.82	Yes	No	5	9	9
2094	T:T:K239	T:T:K243	4.31	Yes	No	5	9	9
2095	T:T:I240	T:T:K241	5.82	No	No	0	9	9
2096	T:T:K243	T:T:L242	4.23	No	No	5	9	9
2097	W:W:?1	X:X:?1	30.28	Yes	Yes	5	0	0
2098	S:S:T726	S:S:Y729	2.5	No	No	0	7	9
2099	S:S:F286	S:S:M308	2.49	No	No	0	4	4
2100	E:E:K177	E:E:R178	2.48	No	Yes	0	9	9
2101	R:R:F808	R:R:K809	2.48	Yes	No	0	7	6
2102	S:S:F808	S:S:K809	2.48	Yes	No	0	7	6
2103	S:S:H140	S:S:Q116	2.47	No	No	0	8	6
2104	S:S:F80	S:S:L55	2.44	Yes	No	0	7	6
2105	S:S:F554	S:S:L558	2.44	No	No	0	3	7
2106	S:S:F623	S:S:L624	2.44	Yes	No	0	4	5
2107	S:S:F706	S:S:L710	2.44	Yes	No	0	5	9
2108	S:S:L575	S:S:R663	2.43	No	No	0	6	4
2109	S:S:L667	S:S:R663	2.43	No	No	0	1	4
2110	E:E:D218	E:E:F217	2.39	No	No	0	9	9
2111	S:S:D598	S:S:R542	2.38	No	No	0	9	9
2112	S:S:I593	S:S:W612	2.35	No	Yes	0	5	9
2113	T:T:F60	T:T:Q206	2.34	No	No	0	8	9
2114	T:T:Q148	T:T:R145	2.34	No	Yes	0	9	9
2115	R:R:D598	R:R:Y534	2.3	Yes	Yes	11	9	4
2116	S:S:L543	S:S:W539	2.28	No	No	0	5	9
2117	S:S:H299	S:S:R275	2.26	No	Yes	0	7	5
2118	S:S:F662	S:S:H658	2.26	No	No	0	4	4
2119	R:R:G305	R:R:G328	2.11	No	No	0	8	7
2120	S:S:G305	S:S:G328	2.11	No	No	0	8	7
2121	R:R:F445	R:R:Y466	2.06	No	Yes	0	1	6
2122	S:S:G699	S:S:P770	2.03	No	No	0	4	9
2123	T:T:R149	T:T:W120	2	No	Yes	0	9	9
2124	L:L:C74	L:L:G42	1.96	Yes	No	0	0	0
2125	L:L:C96	L:L:G81	1.96	No	No	0	0	0
2126	M:M:C78	M:M:G84	1.96	No	No	0	0	0
2127	M:M:C96	M:M:G81	1.96	No	No	0	0	0
2128	R:R:C339	R:R:G363	1.96	No	Yes	64	9	4
2129	R:R:C364	R:R:G363	1.96	No	Yes	64	9	4
2130	R:R:C476	R:R:G475	1.96	No	No	0	8	3
2131	S:S:C339	S:S:G363	1.96	No	No	75	9	4
2132	S:S:C364	S:S:G363	1.96	No	No	75	9	4
2133	S:S:C476	S:S:G475	1.96	No	No	0	8	3
2134	L:L:A130	L:L:G131	1.95	No	No	0	0	0
2135	M:M:A130	M:M:G131	1.95	No	No	0	0	0
2136	R:R:A552	R:R:G588	1.95	No	No	0	8	9
2137	R:R:A625	R:R:G622	1.95	No	No	0	7	8
2138	S:S:A410	S:S:G432	1.95	No	No	0	3	8
2139	S:S:A621	S:S:G622	1.95	No	No	0	5	8
2140	S:S:A625	S:S:G622	1.95	No	No	0	7	8
2141	S:S:A676	S:S:G677	1.95	No	No	0	5	8
2142	T:T:A59	T:T:G83	1.95	No	No	0	9	8
2143	T:T:P209	T:T:P210	1.95	No	No	0	7	9
2144	M:M:C128	M:M:P134	1.88	No	No	0	0	0
2145	R:R:C522	R:R:P524	1.88	No	No	0	9	9
2146	R:R:C761	R:R:P762	1.88	No	No	0	7	9
2147	S:S:C522	S:S:P524	1.88	No	No	0	9	9
2148	L:L:A87	L:L:P88	1.87	No	No	0	0	0
2149	L:L:A133	L:L:P134	1.87	No	No	0	0	0
2150	M:M:A87	M:M:P88	1.87	No	No	0	0	0
2151	M:M:A133	M:M:P134	1.87	No	No	0	0	0
2152	T:T:A153	T:T:P179	1.87	No	Yes	0	9	9
2153	R:R:G527	R:R:S525	1.86	No	No	0	9	4
2154	R:R:G617	R:R:S616	1.86	No	No	0	7	2
2155	S:S:G103	S:S:S102	1.86	No	No	0	8	5
2156	S:S:G617	S:S:S616	1.86	No	No	0	7	2
2157	E:E:G83	E:E:V183	1.84	No	No	0	8	9
2158	R:R:G288	R:R:V287	1.84	No	No	0	9	9
2159	T:T:G83	T:T:V183	1.84	No	No	0	8	9
2160	L:L:C101	L:L:C104	1.82	No	No	0	0	0
2161	E:E:G80	E:E:T79	1.82	No	Yes	0	7	9
2162	E:E:G141	E:E:T138	1.82	No	No	0	6	9
2163	R:R:G387	R:R:T411	1.82	No	No	0	5	4
2164	S:S:G527	S:S:T526	1.82	No	No	0	9	8
2165	S:S:G578	S:S:T563	1.82	No	No	0	8	4
2166	T:T:G80	T:T:T79	1.82	No	No	0	7	9
2167	T:T:G141	T:T:T138	1.82	No	No	0	6	9
2168	R:R:A243	R:R:C220	1.81	No	Yes	0	8	5
2169	R:R:A467	R:R:C470	1.81	No	No	0	9	9
2170	R:R:A472	R:R:C532	1.81	No	No	0	7	9
2171	S:S:A243	S:S:C220	1.81	No	Yes	0	8	5
2172	S:S:A467	S:S:C470	1.81	No	No	0	9	9
2173	S:S:A606	S:S:C471	1.81	No	No	35	6	9
2174	S:S:A606	S:S:C532	1.81	No	No	35	6	9
2175	L:L:P79	L:L:S80	1.78	Yes	No	0	0	0
2176	R:R:P283	R:R:S259	1.78	No	No	0	9	6
2177	R:R:P429	R:R:S406	1.78	No	No	0	9	3
2178	R:R:P571	R:R:S573	1.78	No	No	0	7	5
2179	S:S:P429	S:S:S406	1.78	No	Yes	0	9	3
2180	S:S:P691	S:S:S690	1.78	Yes	No	0	9	8
2181	S:S:P697	S:S:S690	1.78	Yes	No	0	7	8
2182	R:R:G475	R:R:I520	1.76	No	No	0	3	5
2183	S:S:G413	S:S:I389	1.76	No	No	0	3	3
2184	S:S:G578	S:S:I577	1.76	No	No	0	8	5
2185	R:R:P145	R:R:T119	1.75	Yes	No	0	9	5
2186	R:R:P177	R:R:T178	1.75	No	No	0	4	5
2187	E:E:G185	E:E:K184	1.74	No	No	0	9	9
2188	R:R:G103	R:R:K105	1.74	No	No	0	8	3
2189	R:R:G270	R:R:K245	1.74	No	No	0	6	5
2190	S:S:G103	S:S:K105	1.74	No	No	0	8	3
2191	S:S:G537	S:S:K783	1.74	No	No	0	6	9
2192	T:T:G141	T:T:K144	1.74	No	No	0	6	9
2193	T:T:G185	T:T:K184	1.74	No	No	0	9	9
2194	R:R:C220	R:R:S217	1.72	Yes	No	0	5	6
2195	S:S:C220	S:S:S217	1.72	Yes	No	0	5	6
2196	L:L:G72	L:L:L63	1.71	No	Yes	0	0	0
2197	E:E:G105	L:L:L63	1.71	No	Yes	0	9	0
2198	M:M:L63	T:T:G105	1.71	Yes	No	0	0	9
2199	E:E:G89	E:E:L176	1.71	No	No	0	9	9
2200	E:E:G171	E:E:L140	1.71	No	No	0	5	9
2201	E:E:C233	E:E:V232	1.71	No	No	0	8	9
2202	R:R:G238	R:R:L237	1.71	No	Yes	0	2	8
2203	R:R:G387	R:R:L388	1.71	No	Yes	0	5	8
2204	R:R:G413	R:R:L412	1.71	No	No	0	3	8
2205	R:R:C795	R:R:V551	1.71	No	Yes	0	9	6
2206	R:R:G705	R:R:L704	1.71	No	No	0	6	6
2207	R:R:A764	R:R:S767	1.71	No	No	0	9	8
2208	S:S:C35	S:S:V41	1.71	No	No	0	9	7
2209	S:S:G387	S:S:L388	1.71	No	No	0	5	8
2210	S:S:G413	S:S:L412	1.71	No	No	0	3	8
2211	S:S:G537	S:S:L536	1.71	No	Yes	0	6	5
2212	T:T:G89	T:T:L176	1.71	No	No	0	9	9
2213	R:R:G47	R:R:N67	1.7	No	Yes	0	7	9
2214	R:R:G47	R:R:N68	1.7	No	No	0	7	9
2215	R:R:A196	R:R:V170	1.7	No	No	0	9	6
2216	R:R:G254	R:R:N233	1.7	No	Yes	0	7	9
2217	R:R:G270	R:R:N271	1.7	No	Yes	0	6	9
2218	R:R:A306	R:R:V287	1.7	No	No	0	9	9
2219	R:R:G317	R:R:N294	1.7	No	No	0	7	6
2220	R:R:A306	R:R:V309	1.7	No	No	0	9	7
2221	R:R:G363	R:R:N362	1.7	Yes	No	0	4	4
2222	R:R:G432	R:R:N434	1.7	No	No	0	8	3
2223	S:S:G47	S:S:N67	1.7	No	Yes	0	7	9
2224	S:S:A196	S:S:V170	1.7	No	No	0	9	6
2225	S:S:G254	S:S:N233	1.7	No	Yes	0	7	9
2226	S:S:G270	S:S:N271	1.7	No	Yes	0	6	9
2227	S:S:G432	S:S:N434	1.7	No	No	0	8	3
2228	E:E:A224	S:S:T544	1.68	No	No	0	9	9
2229	R:R:D36	R:R:G37	1.68	No	No	0	5	4
2230	R:R:D269	R:R:G270	1.68	No	No	0	3	6
2231	S:S:D36	S:S:G37	1.68	No	No	0	5	4
2232	S:S:D269	S:S:G270	1.68	No	No	0	3	6
2233	T:T:K134	T:T:P133	1.67	No	No	0	9	9
2234	T:T:K134	T:T:P135	1.67	No	No	0	9	9
2235	L:L:L135	L:L:P134	1.64	No	No	0	0	0
2236	E:E:E173	E:E:G171	1.64	No	No	0	9	5
2237	R:R:E53	R:R:G54	1.64	No	No	0	2	4
2238	R:R:L104	R:R:P81	1.64	No	No	0	9	5
2239	R:R:L176	R:R:P177	1.64	Yes	No	0	9	4
2240	R:R:L247	R:R:P248	1.64	No	No	0	9	4
2241	S:S:L104	S:S:P81	1.64	No	No	0	9	5
2242	S:S:L176	S:S:P177	1.64	Yes	No	0	9	4
2243	S:S:E239	S:S:G238	1.64	No	No	0	7	2
2244	S:S:L247	S:S:P248	1.64	Yes	No	0	9	4
2245	S:S:G383	S:S:Q386	1.64	No	No	0	4	4
2246	S:S:L570	S:S:P571	1.64	No	No	0	4	7
2247	S:S:E686	S:S:G685	1.64	Yes	No	0	4	5
2248	T:T:E117	T:T:G119	1.64	No	Yes	0	9	9
2249	R:R:N271	R:R:P272	1.63	Yes	No	0	9	8
2250	R:R:N294	R:R:P272	1.63	No	No	0	6	8
2251	R:R:N282	R:R:P283	1.63	Yes	No	0	9	9
2252	S:S:S44	S:S:S65	1.63	No	No	0	7	9
2253	S:S:N271	S:S:P272	1.63	Yes	No	0	9	8
2254	S:S:N282	S:S:P283	1.63	Yes	No	0	9	9
2255	S:S:N336	S:S:P359	1.63	No	Yes	0	1	9
2256	E:E:A186	E:E:I189	1.62	No	No	0	5	5
2257	E:E:A201	E:E:I194	1.62	No	No	0	9	9
2258	R:R:A632	R:R:I633	1.62	No	Yes	0	5	6
2259	R:R:A717	R:R:I633	1.62	No	Yes	0	9	6
2260	R:R:A774	R:R:I772	1.62	No	No	0	8	8
2261	S:S:A100	S:S:I96	1.62	No	Yes	0	8	9
2262	S:S:S129	S:S:V153	1.62	No	No	0	4	3
2263	S:S:S601	S:S:V600	1.62	No	No	0	9	4
2264	S:S:A632	S:S:I633	1.62	No	Yes	0	5	6
2265	S:S:A717	S:S:I633	1.62	No	Yes	0	9	6
2266	S:S:S715	S:S:V711	1.62	No	No	0	7	9
2267	S:S:A774	S:S:I772	1.62	No	No	0	8	8
2268	T:T:A186	T:T:I189	1.62	No	No	0	5	5
2269	E:E:D132	E:E:P133	1.61	No	No	0	9	9
2270	T:T:D174	T:T:P175	1.61	No	No	0	9	9
2271	E:E:V228	E:E:V232	1.6	No	No	0	9	9
2272	R:R:S94	R:R:T70	1.6	No	No	0	5	8
2273	R:R:S164	R:R:T142	1.6	No	No	0	5	6
2274	R:R:S427	R:R:T426	1.6	No	No	0	4	4
2275	R:R:S703	R:R:T707	1.6	No	No	0	5	5
2276	S:S:S164	S:S:T142	1.6	No	No	0	5	6
2277	S:S:S427	S:S:T426	1.6	No	No	0	4	4
2278	T:T:V228	T:T:V232	1.6	No	No	0	9	9
2279	R:R:G685	R:R:H683	1.59	No	No	0	5	4
2280	R:R:T707	R:R:V708	1.59	No	No	0	5	9
2281	R:R:T786	R:R:V763	1.59	No	No	0	6	9
2282	R:R:T820	R:R:V819	1.59	No	No	0	1	1
2283	S:S:C566	S:S:L814	1.59	No	No	0	5	4
2284	S:S:T707	S:S:V708	1.59	No	No	0	5	9
2285	S:S:T786	S:S:V785	1.59	No	No	0	6	7
2286	E:E:A90	E:E:L92	1.58	No	No	0	9	7
2287	E:E:A143	E:E:L176	1.58	No	No	0	9	9
2288	R:R:A669	R:R:L638	1.58	No	No	0	7	7
2289	S:S:A666	S:S:L638	1.58	No	No	0	5	7
2290	T:T:A88	T:T:L140	1.58	No	No	0	9	9
2291	M:M:C124	M:M:N100	1.57	No	Yes	17	0	0
2292	S:S:E123	S:S:P98	1.57	No	No	0	5	4
2293	T:T:C107	T:T:N109	1.57	No	No	89	9	8
2294	T:T:C136	T:T:N109	1.57	No	No	89	9	8
2295	R:R:A647	R:R:N731	1.56	No	No	0	4	3
2296	S:S:A647	S:S:N731	1.56	No	No	0	4	3
2297	S:S:I746	S:S:S743	1.55	No	No	0	7	4
2298	R:R:A78	R:R:D75	1.54	No	Yes	0	4	4
2299	R:R:A452	R:R:D455	1.54	No	No	0	3	4
2300	R:R:I724	R:R:V723	1.54	Yes	No	0	6	3
2301	S:S:A246	S:S:D222	1.54	No	No	0	5	4
2302	M:M:K112	M:M:S103	1.53	No	No	0	0	0
2303	R:R:K105	R:R:S129	1.53	No	No	0	3	4
2304	S:S:K105	S:S:S129	1.53	No	No	0	3	4
2305	L:L:K114	L:L:V115	1.52	Yes	No	0	0	0
2306	R:R:K343	R:R:V319	1.52	No	No	0	7	4
2307	R:R:K727	R:R:V723	1.52	No	No	0	4	3
2308	R:R:I758	R:R:T755	1.52	No	No	0	7	7
2309	S:S:F605	S:S:G609	1.51	Yes	No	0	9	9
2310	E:E:K190	E:E:T79	1.5	No	Yes	0	9	9
2311	R:R:L645	R:R:S644	1.5	No	No	0	2	6
2312	S:S:L273	S:S:S249	1.5	No	No	0	6	6
2313	S:S:K816	S:S:T820	1.5	No	No	0	4	1
2314	E:E:L242	E:E:V238	1.49	No	No	0	9	8
2315	R:R:N236	R:R:S259	1.49	No	No	0	5	6
2316	R:R:N354	R:R:S332	1.49	No	No	0	3	4
2317	R:R:L550	R:R:V551	1.49	No	Yes	0	3	6
2318	R:R:N740	R:R:S741	1.49	No	No	0	3	3
2319	S:S:N354	S:S:S332	1.49	No	No	0	3	4
2320	S:S:L671	S:S:V675	1.49	No	No	0	1	3
2321	T:T:L191	T:T:V63	1.49	No	No	0	9	9
2322	T:T:V229	X:X:?1	1.49	No	Yes	0	9	0
2323	R:R:N434	R:R:V457	1.48	No	No	0	3	4
2324	R:R:L561	R:R:T562	1.47	No	No	0	4	5
2325	R:R:N68	R:R:T49	1.46	No	No	0	9	4
2326	M:M:G51	M:M:Y71	1.45	No	Yes	0	0	0
2327	M:M:D136	M:M:T138	1.45	No	No	0	0	0
2328	E:E:D187	E:E:T82	1.45	No	No	0	9	8
2329	R:R:G537	R:R:Y534	1.45	No	Yes	0	6	4
2330	T:T:G150	T:T:Y118	1.45	No	Yes	0	9	9
2331	E:E:Q206	E:E:S93	1.44	Yes	No	18	9	9
2332	E:E:S93	T:T:Q206	1.44	No	No	0	9	9
2333	E:E:Q206	T:T:S93	1.44	Yes	No	18	9	9
2334	R:R:Q180	R:R:S202	1.44	Yes	No	0	9	8
2335	R:R:E613	R:R:S688	1.44	Yes	No	0	9	5
2336	R:R:Q742	R:R:S741	1.44	No	No	0	7	3
2337	S:S:F80	S:S:P81	1.44	Yes	No	0	7	5
2338	S:S:E239	S:S:S215	1.44	No	No	0	7	5
2339	S:S:E780	S:S:S778	1.44	No	Yes	0	8	6
2340	E:E:Q167	E:E:V139	1.43	No	No	0	9	9
2341	R:R:I589	R:R:L585	1.43	No	No	0	2	4
2342	R:R:I589	R:R:L624	1.43	No	No	0	2	5
2343	R:R:I746	R:R:L732	1.43	No	No	0	7	7
2344	S:S:I589	S:S:L624	1.43	No	No	0	2	5
2345	T:T:Q167	T:T:V139	1.43	No	Yes	0	9	9
2346	E:E:I189	E:E:N193	1.42	No	No	0	5	9
2347	R:R:Q71	R:R:T70	1.42	No	No	0	4	8
2348	R:R:Q386	R:R:T411	1.42	No	No	0	4	4
2349	S:S:Q71	S:S:T70	1.42	No	No	0	4	8
2350	T:T:I189	T:T:N193	1.42	No	No	0	5	9
2351	E:E:K243	R:R:L732	1.41	No	No	0	9	7
2352	E:E:D166	E:E:I165	1.4	No	Yes	0	9	9
2353	E:E:K197	E:E:N193	1.4	No	No	0	9	9
2354	S:S:K212	S:S:N236	1.4	No	No	0	5	5
2355	S:S:C757	S:S:F718	1.4	No	Yes	0	9	6
2356	T:T:D166	T:T:I165	1.4	No	Yes	0	9	9
2357	R:R:A57	R:R:F80	1.39	No	Yes	0	4	7
2358	R:R:A57	R:R:F82	1.39	No	No	0	4	5
2359	R:R:A666	R:R:F576	1.39	No	Yes	0	5	6
2360	R:R:A669	R:R:F634	1.39	No	Yes	0	7	7
2361	S:S:A57	S:S:F82	1.39	No	No	0	4	5
2362	S:S:C566	S:S:R818	1.39	No	No	0	5	3
2363	S:S:A666	S:S:F576	1.39	No	Yes	0	5	6
2364	M:M:D49	M:M:K48	1.38	No	No	0	0	0
2365	E:E:L140	E:E:L168	1.38	No	Yes	0	9	9
2366	R:R:L553	R:R:L585	1.38	No	No	0	5	4
2367	R:R:D649	R:R:K648	1.38	No	No	0	1	4
2368	S:S:L338	S:S:L348	1.38	No	No	0	5	9
2369	S:S:D649	S:S:K648	1.38	No	No	0	1	4
2370	S:S:L712	S:S:L716	1.38	No	No	0	8	5
2371	R:R:L732	R:R:N731	1.37	No	No	0	7	3
2372	S:S:L732	S:S:N731	1.37	No	No	0	7	3
2373	L:L:K58	L:L:Q57	1.36	Yes	No	0	0	0
2374	E:E:D114	E:E:L115	1.36	No	No	0	9	8
2375	R:R:K381	R:R:Q379	1.36	No	No	0	1	5
2376	R:R:M745	R:R:Q742	1.36	Yes	No	0	7	7
2377	S:S:D649	S:S:L645	1.36	No	No	0	1	2
2378	S:S:E341	S:S:K343	1.35	No	No	0	5	7
2379	S:S:E449	S:S:K448	1.35	No	No	0	4	7
2380	M:M:C141	M:M:Y118	1.34	Yes	No	24	0	0
2381	E:E:L92	T:T:Q206	1.33	No	No	0	7	9
2382	E:E:L131	E:E:Q128	1.33	No	No	0	9	9
2383	R:R:L400	R:R:Q376	1.33	No	No	0	3	4
2384	T:T:E173	T:T:L140	1.33	No	No	0	9	9
2385	E:E:N169	E:E:Q170	1.32	Yes	No	0	9	8
2386	R:R:F58	R:R:S56	1.32	No	No	0	6	6
2387	R:R:F286	R:R:S285	1.32	No	No	0	4	8
2388	R:R:N657	R:R:Q661	1.32	No	No	0	3	5
2389	S:S:F95	S:S:S94	1.32	No	No	0	3	5
2390	S:S:R214	S:S:S190	1.32	No	No	0	3	3
2391	R:R:F789	R:R:V763	1.31	Yes	No	0	7	9
2392	S:S:F760	S:S:V763	1.31	Yes	No	0	8	9
2393	S:S:F789	S:S:V763	1.31	Yes	No	0	7	9
2394	S:S:F790	S:S:V763	1.31	Yes	No	0	5	9
2395	S:S:A599	S:S:W546	1.3	No	No	0	5	9
2396	T:T:E117	T:T:E97	1.27	No	No	0	9	7
2397	R:R:E322	R:R:H299	1.23	No	No	0	8	7
2398	R:R:F670	R:R:L671	1.22	Yes	No	0	3	1
2399	S:S:F549	S:S:L550	1.22	Yes	No	0	5	3
2400	E:E:L131	L:L:R54	1.21	No	No	0	9	0
2401	R:R:L575	R:R:R663	1.21	No	No	0	6	4
2402	T:T:N169	T:T:R87	1.21	No	No	0	9	5
2403	E:E:D114	L:L:R65	1.19	No	No	0	9	0
2404	E:E:K239	R:R:Y729	1.19	No	No	0	9	9
2405	R:R:D36	R:R:R40	1.19	No	Yes	0	5	3
2406	R:R:I610	R:R:W611	1.17	No	No	0	7	4
2407	S:S:Q376	S:S:R356	1.17	No	No	0	4	3
2408	S:S:I518	S:S:W474	1.17	No	No	0	4	4
2409	T:T:Q212	T:T:R211	1.17	Yes	No	0	8	8
2410	S:S:W611	S:S:W612	0.94	No	Yes	0	4	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:D49	5.9025	4	3	0
2	L:L:N50	6.185	6	3	0
3	L:L:C52	5.2075	4	3	0
4	L:L:C55	4.19	4	3	0
5	L:L:K58	4.3925	4	0	0
6	L:L:F60	4.87	4	1	0
7	L:L:F61	5.348	5	3	0
8	L:L:F62	8.0625	4	1	0
9	L:L:L63	5.052	5	3	0
10	L:L:C74	6.115	4	3	0
11	L:L:P79	4.085	4	1	0
12	L:L:Y82	8.708	5	1	0
13	L:L:R86	7.552	5	1	0
14	L:L:C93	4.2225	4	1	0
15	L:L:I98	4.04	4	22	0
16	L:L:N100	7.7375	4	22	0
17	L:L:F105	7.42167	6	1	0
18	L:L:F109	5.56833	6	1	0
19	L:L:C110	4.9125	4	22	0
20	L:L:K114	4.464	5	22	0
21	L:L:H120	9.4	4	27	0
22	L:L:R123	6.1475	4	0	0
23	L:L:P129	5.152	5	27	0
24	L:L:C141	5.245	4	27	0
25	M:M:N50	6.45167	6	4	0
26	M:M:K58	9.378	5	6	0
27	M:M:L59	3.6125	4	4	0
28	M:M:F61	5.60167	6	4	0
29	M:M:F62	7.8875	4	12	0
30	M:M:L63	5.2325	4	0	0
31	M:M:Y71	7.192	5	12	0
32	M:M:Y82	8.43	5	12	0
33	M:M:R86	6.14143	7	6	0
34	M:M:N100	8.0525	4	17	0
35	M:M:F105	6.41333	6	6	0
36	M:M:F109	5.04143	7	6	0
37	M:M:C110	4.9125	4	17	0
38	M:M:K114	3.94	5	17	0
39	M:M:F117	7.4175	4	17	0
40	M:M:H120	6.205	4	24	0
41	M:M:P129	4.6025	4	24	0
42	M:M:C141	4.2025	4	24	0
43	E:E:T58	4.575	4	18	8
44	E:E:F60	5.96	5	18	8
45	E:E:T79	2.865	4	7	9
46	E:E:F85	7.08	4	41	8
47	E:E:E95	12.7675	4	0	8
48	E:E:H102	8	5	3	9
49	E:E:Y116	6.132	5	0	9
50	E:E:Y118	6.15429	7	29	9
51	E:E:W120	5.342	5	0	9
52	E:E:K125	6.6125	4	3	9
53	E:E:R145	4.88	4	54	9
54	E:E:I155	3.015	4	0	9
55	E:E:F156	4.936	5	55	9
56	E:E:D157	5.42	4	3	9
57	E:E:N161	6.8875	4	56	9
58	E:E:I165	4.5975	4	28	9
59	E:E:L168	3.755	4	0	9
60	E:E:N169	4.2025	4	28	9
61	E:E:R178	6.464	5	0	9
62	E:E:Y182	7.248	5	28	9
63	E:E:M192	3.905	4	3	9
64	E:E:V195	3.7475	4	3	9
65	E:E:R202	8.05	4	7	9
66	E:E:R204	10.56	5	7	9
67	E:E:Q206	4.46	4	18	9
68	E:E:H207	5.385	4	41	9
69	E:E:P209	7.69	4	18	7
70	E:E:P210	5.88	4	18	9
71	E:E:E215	9.554	5	9	9
72	E:E:Y216	5.342	5	9	9
73	R:R:R40	7.0525	4	58	3
74	R:R:V41	5.905	4	57	7
75	R:R:S44	4.895	4	42	7
76	R:R:D63	6.1975	4	42	9
77	R:R:N67	5.348	5	59	9
78	R:R:L72	5.6325	4	0	7
79	R:R:D75	5.405	4	38	4
80	R:R:F80	4.556	5	0	7
81	R:R:L88	5.006	5	0	9
82	R:R:I96	4.785	4	60	9
83	R:R:H97	13.4425	4	38	8
84	R:R:K99	5.61	4	38	3
85	R:R:L110	4.154	5	8	9
86	R:R:L112	4.1475	4	0	9
87	R:R:Q113	5.1425	4	1	9
88	R:R:N115	4.455	4	61	9
89	R:R:V120	3.9075	4	0	7
90	R:R:L131	3.4625	4	8	9
91	R:R:L134	4.54333	6	8	9
92	R:R:R135	7.852	5	1	9
93	R:R:D137	6.094	5	1	9
94	R:R:N139	5.16	4	61	9
95	R:R:I141	5.02	4	0	9
96	R:R:V144	4.175	4	8	9
97	R:R:P145	3.48	5	8	9
98	R:R:F149	5.58	5	8	9
99	R:R:R156	6.0825	4	0	9
100	R:R:H157	4.97167	6	0	9
101	R:R:L158	3.335	4	8	9
102	R:R:W159	8.66	5	1	9
103	R:R:D161	7.006	5	1	9
104	R:R:V168	3.515	4	0	8
105	R:R:H171	5.6925	4	8	1
106	R:R:P172	4.2725	4	8	9
107	R:R:L176	4.355	4	0	9
108	R:R:Q180	3.7075	4	1	9
109	R:R:L182	4.025	4	0	8
110	R:R:T183	5.06	4	1	9
111	R:R:L184	3.825	4	0	9
112	R:R:I192	3.244	5	2	8
113	R:R:F197	3.798	5	0	9
114	R:R:V204	4.51	5	1	9
115	R:R:V205	5.212	5	1	9
116	R:R:H207	6.31	6	1	9
117	R:R:L208	4.442	5	2	9
118	R:R:H209	5.18	5	1	9
119	R:R:N210	9.73	4	1	9
120	R:R:N211	5.016	5	2	9
121	R:R:I213	4.98333	6	2	9
122	R:R:L216	3.302	5	2	6
123	R:R:H219	9.4775	4	62	5
124	R:R:C220	4.546	5	2	5
125	R:R:F221	6.14	4	0	9
126	R:R:T229	4.81	4	1	9
127	R:R:L230	4.635	4	0	9
128	R:R:D231	6.5075	4	1	9
129	R:R:N233	6.2175	4	1	9
130	R:R:N235	6.6	4	2	9
131	R:R:L237	2.91333	6	2	8
132	R:R:F240	5.16714	7	2	9
133	R:R:P241	5.5	4	2	9
134	R:R:K251	6.5525	4	0	9
135	R:R:L253	4.9	4	2	9
136	R:R:F255	4.645	6	2	9
137	R:R:H256	12.99	4	1	9
138	R:R:N258	5.645	4	2	9
139	R:R:I260	3.274	5	2	9
140	R:R:F268	3.69333	6	2	9
141	R:R:N271	3.46167	6	2	9
142	R:R:L274	5.425	4	2	9
143	R:R:I277	4.465	4	2	8
144	R:R:N282	4.2	4	2	9
145	R:R:H293	4.95	4	63	7
146	R:R:I303	3.62	4	0	8
147	R:R:F312	7.3175	4	19	8
148	R:R:T318	3.685	4	32	8
149	R:R:T325	5.62	4	31	8
150	R:R:L326	3.576	5	19	7
151	R:R:T327	6.03	5	31	9
152	R:R:I331	5.3425	4	19	8
153	R:R:Q342	4.2	5	32	8
154	R:R:D349	4.7325	4	31	8
155	R:R:L350	4.1725	4	0	9
156	R:R:N353	5.946	5	19	9
157	R:R:P359	4.41	4	0	9
158	R:R:G363	2.5975	4	64	4
159	R:R:I370	3.8375	4	0	7
160	R:R:L372	3.618	5	0	8
161	R:R:N375	6.434	5	19	9
162	R:R:L388	4.0675	4	0	8
163	R:R:L391	3.8475	4	0	9
164	R:R:L396	3.1875	4	0	9
165	R:R:I401	4.66	4	0	8
166	R:R:I404	4.0825	4	0	7
167	R:R:R407	5.7325	4	39	4
168	R:R:F409	5.204	5	23	8
169	R:R:I415	5.35	4	23	7
170	R:R:L418	3.60167	6	23	9
171	R:R:F422	7.2075	4	43	4
172	R:R:F428	5.215	4	23	4
173	R:R:L433	5.73	4	23	9
174	R:R:L436	3.616	5	23	8
175	R:R:Q438	9.7825	4	30	9
176	R:R:L439	5.6325	4	23	8
177	R:R:K440	9.7125	4	30	8
178	R:R:F456	5.74	4	0	5
179	R:R:Y466	5.2075	4	0	6
180	R:R:Y468	9.906	5	11	9
181	R:R:F473	5.57	4	0	8
182	R:R:Y534	4.126	5	11	4
183	R:R:L535	4.316	5	11	9
184	R:R:L536	5.9075	4	11	5
185	R:R:M540	7.03	5	0	5
186	R:R:I541	8.5925	4	9	7
187	R:R:F549	7.275	4	44	5
188	R:R:V551	3.75	4	0	6
189	R:R:N556	6.395	4	68	9
190	R:R:F576	4.0125	4	33	6
191	R:R:N584	4.0225	4	0	9
192	R:R:F586	3.9325	4	0	6
193	R:R:M587	5.8075	4	67	6
194	R:R:D598	5.2	4	11	9
195	R:R:F605	6.01	5	11	9
196	R:R:W612	5.5975	4	0	9
197	R:R:E613	5.298	5	11	9
198	R:R:F627	4.88	4	0	5
199	R:R:E630	6.286	5	10	8
200	R:R:I633	3.02833	6	10	6
201	R:R:F634	4.184	5	10	7
202	R:R:L635	4.86	4	70	5
203	R:R:E642	7.928	5	33	8
204	R:R:R643	7.24833	6	33	8
205	R:R:F670	4.02	4	70	3
206	R:R:P680	8.0675	4	13	7
207	R:R:E686	6.766	5	13	4
208	R:R:Y687	6.1175	4	13	5
209	R:R:P691	4.342	5	11	9
210	R:R:L692	3.675	4	13	7
211	R:R:L694	5.0875	4	13	7
212	R:R:P695	5.34	5	13	9
213	R:R:P697	5.975	4	13	7
214	R:R:F706	5.132	5	13	5
215	R:R:N714	5.9125	4	10	9
216	R:R:F718	3.618	5	10	6
217	R:R:I724	3.75	4	0	6
218	R:R:M745	4.414	5	0	7
219	R:R:W751	7.832	5	5	8
220	R:R:F754	8.8475	4	0	8
221	R:R:F759	8.3425	4	71	9
222	R:R:E780	7.34	4	9	8
223	R:R:I781	5.61	4	0	8
224	R:R:F789	3.1	5	0	7
225	R:R:P791	4.065	4	67	9
226	R:R:Y801	13.4175	4	69	9
227	R:R:F808	5.795	6	0	7
228	R:R:L814	4.1725	4	0	4
229	S:S:P52	3.548	5	25	8
230	S:S:I64	5.13833	6	25	6
231	S:S:N67	5.062	5	25	9
232	S:S:F77	5.3525	4	0	7
233	S:S:F80	8.015	4	0	7
234	S:S:E85	6.0125	4	0	8
235	S:S:L86	4.6775	4	0	8
236	S:S:I96	4.8325	4	0	9
237	S:S:H97	12.2375	4	45	8
238	S:S:K99	4.17	4	45	3
239	S:S:L110	4.706	5	0	9
240	S:S:Q113	5.21714	7	6	9
241	S:S:N114	3.38	4	6	9
242	S:S:V120	3.71	5	14	7
243	S:S:L134	4.7175	4	0	9
244	S:S:R135	10.82	4	6	9
245	S:S:L136	4.195	6	14	9
246	S:S:D137	9.682	5	6	9
247	S:S:I141	5.178	5	14	9
248	S:S:V144	3.775	4	14	9
249	S:S:P145	5.32	4	14	9
250	S:S:F149	4.6	5	0	9
251	S:S:H157	6.805	6	6	9
252	S:S:W159	7.604	5	6	9
253	S:S:N163	5.8875	4	14	9
254	S:S:L176	4.09	4	0	9
255	S:S:L182	4.29833	6	0	8
256	S:S:L184	4.438	5	0	9
257	S:S:L186	4.425	4	6	9
258	S:S:I192	3.304	5	20	8
259	S:S:F195	5.9475	4	46	2
260	S:S:F197	3.302	5	20	9
261	S:S:L203	4.155	4	73	9
262	S:S:V204	4.845	4	6	9
263	S:S:V205	4.88	6	6	9
264	S:S:L206	4.1525	4	0	9
265	S:S:H207	7.315	4	6	9
266	S:S:L208	4.162	5	20	9
267	S:S:H209	4.225	4	0	9
268	S:S:N210	7.3375	4	0	9
269	S:S:N211	5.6025	4	20	9
270	S:S:I213	4.828	5	20	9
271	S:S:L216	4.165	4	20	6
272	S:S:H219	11.3175	4	46	5
273	S:S:C220	4.228	5	20	5
274	S:S:N233	5.928	5	47	9
275	S:S:Y234	9.0025	4	47	6
276	S:S:F240	5.512	5	0	9
277	S:S:L247	3.4	4	0	9
278	S:S:L250	3.1075	4	15	9
279	S:S:K251	4.81	4	0	9
280	S:S:L253	4.718	5	0	9
281	S:S:F255	4.935	6	15	9
282	S:S:H256	11.27	5	47	9
283	S:S:N258	5.77	4	15	9
284	S:S:F268	4.298	5	15	9
285	S:S:N271	3.24	6	15	9
286	S:S:L274	3.508	5	15	9
287	S:S:R275	6.9525	4	0	5
288	S:S:I277	3.686	5	15	8
289	S:S:N282	3.545	4	15	9
290	S:S:V287	3.53	4	0	9
291	S:S:F292	3.8025	4	0	9
292	S:S:V309	3.6075	4	34	7
293	S:S:T325	4.43	4	48	8
294	S:S:L326	3.9675	4	0	7
295	S:S:T327	6.4525	4	48	9
296	S:S:T329	5.8125	4	34	8
297	S:S:I331	4.888	5	34	8
298	S:S:Q342	5.28	4	0	8
299	S:S:L350	3.892	5	0	9
300	S:S:S351	4.8825	4	0	9
301	S:S:N353	5.946	5	34	9
302	S:S:P359	4.0025	4	0	9
303	S:S:I370	4.212	5	0	7
304	S:S:L372	3.8375	4	0	8
305	S:S:Q373	5.57	5	76	8
306	S:S:R392	8.16	4	0	6
307	S:S:L394	5.2225	4	0	7
308	S:S:I401	4.9875	4	16	8
309	S:S:S406	2.52	4	40	3
310	S:S:R407	5.3875	4	40	4
311	S:S:L418	4.054	5	0	9
312	S:S:L425	4.2575	4	16	9
313	S:S:F428	4.018	5	16	4
314	S:S:N437	3.7125	4	7	5
315	S:S:L439	4.784	5	16	8
316	S:S:L441	4.0225	4	16	8
317	S:S:N458	3.3575	4	7	4
318	S:S:L462	4.4525	4	0	7
319	S:S:Y468	9.815	4	21	9
320	S:S:I519	5.4475	4	18	4
321	S:S:L535	6.295	4	21	9
322	S:S:L536	4.008	5	21	5
323	S:S:F549	3.776	5	79	5
324	S:S:N556	4.765	4	36	9
325	S:S:F576	3.835	4	26	6
326	S:S:I580	3.46	5	36	7
327	S:S:N584	5.04833	6	36	9
328	S:S:Y590	7.5725	4	0	5
329	S:S:T595	3.854	5	79	7
330	S:S:F605	5.622	5	21	9
331	S:S:W612	4.055	6	0	9
332	S:S:E613	5.3075	4	21	9
333	S:S:F623	4.3825	4	0	4
334	S:S:F627	5.585	4	0	5
335	S:S:E630	6.104	5	83	8
336	S:S:I633	3.006	5	0	6
337	S:S:F634	4.1325	4	83	7
338	S:S:E642	6.834	5	26	8
339	S:S:R643	6.394	5	26	8
340	S:S:E686	5.43	5	0	4
341	S:S:Y687	5.5525	4	82	5
342	S:S:P691	3.19333	6	21	9
343	S:S:L694	5.0875	4	49	7
344	S:S:P697	4.975	4	49	7
345	S:S:F706	6.184	5	85	5
346	S:S:N714	6.2175	4	0	9
347	S:S:F718	3.03	4	0	6
348	S:S:Y725	5.9425	4	0	8
349	S:S:W751	7.342	5	5	8
350	S:S:N756	4.005	4	0	9
351	S:S:F760	4.03	4	0	8
352	S:S:F766	5.725	4	0	9
353	S:S:S778	2.98	4	0	6
354	S:S:I781	4.542	5	9	8
355	S:S:F789	3.995	4	0	7
356	S:S:F790	3.955	4	0	5
357	S:S:N797	4.44167	6	36	9
358	S:S:P798	3.9825	4	36	9
359	S:S:Y801	6.636	5	80	9
360	S:S:N805	9.5025	4	80	8
361	S:S:F808	8.09	4	0	7
362	S:S:D811	5.45	4	0	9
363	T:T:V64	4.38	5	29	9
364	T:T:Y77	5.3825	4	66	6
365	T:T:T78	3.1975	4	0	9
366	T:T:F85	6.872	5	37	8
367	T:T:E95	11.44	4	0	8
368	T:T:V99	5.435	4	7	7
369	T:T:M101	5.0625	4	7	9
370	T:T:H102	7.862	5	4	9
371	T:T:L104	4.9075	4	4	9
372	T:T:Y116	5.258	5	7	9
373	T:T:Y118	5.55857	7	7	9
374	T:T:G119	3.398	5	7	9
375	T:T:W120	5.73143	7	7	9
376	T:T:K125	7.3225	4	4	9
377	T:T:E127	5.735	4	4	9
378	T:T:Q128	6.0975	4	4	9
379	T:T:L131	5.102	5	4	9
380	T:T:V139	2.605	4	0	9
381	T:T:R145	5.6275	4	0	9
382	T:T:F156	3.45667	6	0	9
383	T:T:D157	6.805	4	4	9
384	T:T:I165	4.93	4	88	9
385	T:T:R178	6.6	5	0	9
386	T:T:P179	3.575	4	0	9
387	T:T:Y182	6.838	5	88	9
388	T:T:M192	5.305	4	4	9
389	T:T:R202	6.188	5	29	9
390	T:T:R204	10.57	5	29	9
391	T:T:Q212	9.5225	4	9	8
392	T:T:E215	5.68	5	9	9
393	T:T:D218	8.746	5	9	9
394	T:T:M219	7.95	5	9	9
395	T:T:F222	5.12	5	9	9
396	T:T:L223	5.7325	4	9	9
397	T:T:F226	9.5175	4	5	9
398	T:T:L236	5.885	4	5	9
399	T:T:K239	5.7725	4	5	9
400	W:W:?1	9.02	10	5	0
401	X:X:?1	12.7022	9	5	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:C43	L:L:C52	100	7.28	No	Yes	3	0	0
2	L:L:C43	L:L:C55	100	3.64	No	Yes	3	0	0
3	L:L:C55	L:L:Q56	100	3.05	Yes	No	0	0	0
4	E:E:A164	E:E:N161	11.3319	4.69	No	Yes	0	9	9
5	E:E:A164	E:E:V158	12.465	3.39	No	No	0	9	9
6	E:E:V158	E:E:Y182	13.5976	5.05	No	Yes	28	9	9
7	E:E:R84	E:E:Y182	44.1875	9.26	No	Yes	0	8	9
8	E:E:R84	E:E:T58	45.3203	6.47	No	Yes	0	8	8
9	E:E:F60	E:E:T58	23.65	5.19	Yes	Yes	18	8	8
10	E:E:F60	E:E:P209	12.69	10.11	Yes	Yes	18	8	7
11	E:E:P209	E:E:Q206	25.8942	9.47	Yes	Yes	18	7	9
12	E:E:Q206	E:E:S93	38.9123	1.44	Yes	No	18	9	9
13	E:E:S93	T:T:Q206	39.2207	1.44	No	No	0	9	9
14	T:T:F60	T:T:Q206	40.8866	2.34	No	No	0	8	9
15	T:T:F60	T:T:T58	100	5.19	No	No	0	8	8
16	T:T:R84	T:T:T58	100	6.47	No	No	0	8	8
17	T:T:R84	T:T:Y182	100	7.2	No	Yes	0	8	9
18	T:T:S86	T:T:Y182	100	5.09	No	Yes	0	9	9
19	T:T:L168	T:T:S86	100	7.51	No	No	0	9	9
20	T:T:L168	T:T:V139	100	2.98	No	Yes	0	9	9
21	T:T:F156	T:T:V139	100	2.62	Yes	Yes	0	9	9
22	T:T:F156	T:T:V124	100	5.24	Yes	No	0	9	9
23	T:T:P103	T:T:V124	100	3.53	No	No	0	9	9
24	T:T:H102	T:T:P103	100	10.68	Yes	No	4	9	9
25	M:M:L63	T:T:H102	100	5.14	Yes	Yes	0	0	9
26	M:M:L63	M:M:Q70	100	7.99	Yes	No	0	0	0
27	M:M:Q70	M:M:R65	100	16.35	No	No	0	0	0
28	M:M:R65	T:T:V99	100	3.92	No	Yes	7	0	7
29	T:T:V99	T:T:W120	100	12.26	Yes	Yes	7	7	9
30	T:T:G119	T:T:W120	100	2.81	Yes	Yes	7	9	9
31	E:E:R202	T:T:G119	100	6	Yes	Yes	7	9	9
32	E:E:E95	E:E:R202	100	18.61	Yes	Yes	0	8	9
33	E:E:E95	T:T:E95	100	3.81	Yes	Yes	0	8	8
34	T:T:E95	T:T:R202	100	15.12	Yes	Yes	0	8	9
35	E:E:G119	T:T:R202	100	4.5	No	Yes	29	9	9
36	E:E:G119	E:E:W120	100	2.81	No	Yes	0	9	9
37	E:E:V99	E:E:W120	100	4.9	No	Yes	0	7	9
38	E:E:V99	E:E:Y116	100	2.52	No	Yes	0	7	9
39	E:E:Y116	L:L:R65	100	13.38	Yes	No	0	9	0
40	L:L:Q70	L:L:R65	100	14.02	No	No	0	0	0
41	L:L:L63	L:L:Q70	100	9.32	Yes	No	3	0	0
42	L:L:F61	L:L:L63	100	6.09	Yes	Yes	3	0	0
43	L:L:C55	L:L:F61	100	2.79	Yes	Yes	3	0	0
44	E:E:P210	E:E:T58	23.338	3.5	Yes	Yes	18	9	8
45	E:E:P209	E:E:P210	13.7195	7.79	Yes	Yes	18	7	9
46	E:E:F60	S:S:I519	13.2258	6.28	Yes	Yes	18	8	4
47	E:E:Q206	S:S:I519	13.2666	5.49	Yes	Yes	18	9	4
48	T:T:V158	T:T:Y182	100	5.05	No	Yes	88	9	9
49	T:T:A164	T:T:V158	100	3.39	No	No	0	9	9
50	T:T:A164	T:T:V139	100	3.39	No	Yes	0	9	9
51	M:M:R65	T:T:Y116	100	10.29	No	Yes	7	0	9
52	T:T:W120	T:T:Y116	100	2.89	Yes	Yes	7	9	9
53	T:T:G119	T:T:T152	100	3.64	Yes	No	0	9	9
54	E:E:E95	T:T:T152	100	4.23	Yes	No	0	8	9
55	E:E:M101	E:E:W120	100	5.82	No	Yes	0	9	9
56	E:E:M101	E:E:Y116	100	7.18	No	Yes	0	9	9
57	E:E:H102	L:L:N50	100	12.75	Yes	Yes	3	9	0
58	L:L:D49	L:L:N50	96.1894	2.69	Yes	Yes	3	0	0
59	E:E:H102	E:E:L104	14.0793	6.43	Yes	No	3	9	9
60	E:E:K125	L:L:N50	100	5.6	Yes	Yes	3	9	0
61	E:E:M192	L:L:D49	91.6096	5.54	Yes	Yes	3	9	0
62	E:E:K125	E:E:M192	91.6091	2.88	Yes	Yes	3	9	9
63	E:E:M192	E:E:V195	100	3.04	Yes	Yes	3	9	9
64	E:E:V195	L:L:M68	100	3.04	Yes	No	3	9	0
65	E:E:A201	L:L:M68	100	3.22	No	No	0	9	0
66	E:E:A201	E:E:I194	100	1.62	No	No	0	9	9
67	E:E:I194	E:E:Q198	100	5.49	No	No	0	9	9
68	E:E:K197	E:E:Q198	82.4495	4.07	No	No	0	9	9
69	E:E:K197	E:E:N196	45.8054	13.99	No	No	0	9	9
70	E:E:N196	L:L:R69	36.6443	3.62	No	No	0	9	0
71	L:L:R69	L:L:Y71	18.3222	9.26	No	No	50	0	0
72	L:L:C52	L:L:E73	82.2389	3.04	Yes	No	0	0	0
73	L:L:C74	L:L:L59	100	7.94	Yes	No	0	0	0
74	L:L:H76	L:L:L59	100	6.43	No	No	0	0	0
75	L:L:H76	R:R:G90	100	3.18	No	No	0	0	9
76	R:R:G90	R:R:N114	100	5.09	No	No	0	9	9
77	L:L:K58	R:R:N114	100	4.2	Yes	No	0	0	9
78	L:L:K58	R:R:H140	36.5532	7.86	Yes	No	0	0	8
79	L:L:K58	R:R:D162	100	4.15	Yes	No	0	0	9
80	L:L:E73	L:L:L75	77.6734	3.98	No	No	0	0	0
81	L:L:L75	L:L:P79	73.108	3.28	No	Yes	0	0	0
82	L:L:F62	L:L:P79	22.8521	4.33	Yes	Yes	1	0	0
83	L:L:C93	L:L:F62	13.7184	2.79	Yes	Yes	1	0	0
84	L:L:C93	L:L:F60	18.3075	2.79	Yes	Yes	1	0	0
85	L:L:P79	L:L:Y82	41.1252	6.95	Yes	Yes	1	0	0
86	L:L:C93	L:L:Y82	13.7227	4.03	Yes	Yes	1	0	0
87	L:L:F60	L:L:G84	18.2744	4.52	Yes	No	0	0	0
88	L:L:F60	L:L:R86	18.3099	8.55	Yes	Yes	1	0	0
89	E:E:I98	E:E:V195	18.3221	4.61	No	Yes	3	8	9
90	R:R:A138	R:R:N114	100	4.69	No	No	0	9	9
91	R:R:A138	R:R:D137	100	3.09	No	Yes	1	9	9
92	R:R:D137	R:R:R135	100	4.76	Yes	Yes	1	9	9
93	L:L:R95	L:L:Y82	18.2789	15.43	No	Yes	0	0	0
94	L:L:A94	L:L:Y83	18.2744	6.67	No	No	0	0	0
95	L:L:C104	L:L:Y83	54.8231	4.03	No	No	0	0	0
96	L:L:C101	L:L:C104	100	1.82	No	No	0	0	0
97	L:L:C101	L:L:I98	100	4.91	No	Yes	22	0	0
98	L:L:I98	L:L:R123	100	2.51	Yes	Yes	0	0	0
99	L:L:R123	R:R:K251	100	4.95	Yes	Yes	0	0	9
100	R:R:E252	R:R:K251	100	6.75	No	Yes	0	9	9
101	R:R:E252	R:R:T229	100	4.23	No	Yes	0	9	9
102	R:R:H207	R:R:T229	100	2.74	Yes	Yes	1	9	9
103	R:R:H207	R:R:T183	100	5.48	Yes	Yes	1	9	9
104	R:R:D161	R:R:T183	100	7.23	Yes	Yes	1	9	9
105	L:L:R86	R:R:D161	100	10.72	Yes	Yes	1	0	9
106	L:L:K107	L:L:Y83	18.2744	5.97	No	No	0	0	0
107	R:R:D162	R:R:L186	100	8.14	No	No	0	9	9
108	L:L:P88	R:R:L186	18.273	3.28	No	No	1	0	9
109	R:R:L186	R:R:N210	91.3713	8.24	No	Yes	1	9	9
110	L:L:R95	L:L:R97	13.7092	5.33	No	No	0	0	0
111	L:L:C104	L:L:C96	36.5487	3.64	No	No	0	0	0
112	L:L:E99	L:L:I98	100	5.47	No	Yes	0	0	0
113	L:L:C110	L:L:I98	73.0968	3.27	Yes	Yes	22	0	0
114	L:L:E99	L:L:N100	100	7.89	No	Yes	0	0	0
115	L:L:K114	L:L:N100	100	4.2	Yes	Yes	22	0	0
116	L:L:F117	L:L:N100	36.5486	15.71	No	Yes	22	0	0
117	L:L:C110	L:L:C124	18.2747	3.64	Yes	No	22	0	0
118	L:L:D102	L:L:K114	54.823	6.91	No	Yes	0	0	0
119	L:L:D102	L:L:K112	36.5487	5.53	No	No	0	0	0
120	L:L:K112	L:L:S103	18.2743	3.06	No	No	0	0	0
121	R:R:D161	R:R:W159	100	4.47	Yes	Yes	1	9	9
122	L:L:F105	R:R:W159	100	14.03	Yes	Yes	1	0	9
123	L:L:F105	R:R:T183	100	3.89	Yes	Yes	1	0	9
124	L:L:F105	L:L:S106	45.6838	7.93	Yes	No	0	0	0
125	L:L:S106	R:R:H207	18.2738	5.58	No	Yes	0	0	9
126	L:L:F105	L:L:F109	100	6.43	Yes	Yes	1	0	0
127	R:R:H157	R:R:W159	100	3.17	Yes	Yes	0	9	9
128	L:L:F109	R:R:H157	100	5.66	Yes	Yes	0	0	9
129	L:L:F105	R:R:A181	45.6845	8.32	Yes	No	0	0	9
130	R:R:A181	R:R:H157	27.4106	2.93	No	Yes	0	9	9
131	L:L:F105	R:R:V205	100	3.93	Yes	Yes	1	0	9
132	R:R:H207	R:R:V205	100	4.15	Yes	Yes	1	9	9
133	L:L:D108	L:L:R123	18.2743	10.72	No	Yes	0	0	0
134	L:L:F109	L:L:G122	73.0934	6.02	Yes	No	0	0	0
135	L:L:F109	R:R:Q180	100	3.51	Yes	Yes	1	0	9
136	R:R:H157	R:R:R156	100	5.64	Yes	Yes	0	9	9
137	R:R:Q180	R:R:R156	54.8307	7.01	Yes	Yes	0	9	9
138	L:L:F109	R:R:V204	100	6.55	Yes	Yes	1	0	9
139	R:R:V204	R:R:V205	100	4.81	Yes	Yes	1	9	9
140	L:L:C110	L:L:C113	36.5485	5.46	Yes	No	22	0	0
141	L:L:T111	R:R:H157	27.4107	6.85	No	Yes	0	0	9
142	L:L:C113	L:L:L119	18.2743	7.94	No	No	0	0	0
143	L:L:G116	L:L:K114	18.2743	3.49	No	Yes	0	0	0
144	L:L:D126	L:L:F117	18.2743	3.58	No	No	0	0	0
145	L:L:C128	L:L:P129	100	3.77	No	Yes	27	0	0
146	L:L:H120	L:L:P129	100	4.58	Yes	Yes	27	0	0
147	L:L:H120	L:L:R121	100	12.41	Yes	No	0	0	0
148	L:L:R121	R:R:V204	100	2.62	No	Yes	0	0	9
149	L:L:C128	L:L:C141	100	7.28	No	Yes	27	0	0
150	L:L:C141	L:L:H120	100	5.9	Yes	Yes	27	0	0
151	L:L:C141	L:L:Y118	100	4.03	Yes	No	27	0	0
152	L:L:M139	L:L:Y118	100	4.79	No	No	0	0	0
153	L:L:F132	L:L:H120	100	14.71	No	Yes	27	0	0
154	L:L:R121	R:R:N226	100	8.44	No	No	0	0	8
155	L:L:F125	L:L:R123	18.2743	6.41	No	Yes	0	0	0
156	L:L:E127	L:L:P129	100	7.86	No	Yes	0	0	0
157	L:L:F132	L:L:G131	100	3.01	No	No	0	0	0
158	M:M:F61	M:M:L63	100	6.09	Yes	Yes	0	0	0
159	M:M:C55	M:M:F61	100	4.19	No	Yes	4	0	0
160	M:M:C55	M:M:L59	100	3.17	No	Yes	4	0	0
161	M:M:L59	M:M:Q56	100	2.66	Yes	No	0	0	0
162	M:M:L44	M:M:Q56	100	2.66	No	No	0	0	0
163	M:M:R54	T:T:L131	100	7.29	No	Yes	4	0	9
164	M:M:N50	T:T:K125	11.9698	6.99	Yes	Yes	4	0	9
165	M:M:F61	T:T:L104	100	6.09	Yes	Yes	4	0	9
166	T:T:H102	T:T:L104	100	7.71	Yes	Yes	4	9	9
167	M:M:H76	M:M:L59	100	3.86	No	Yes	0	0	0
168	M:M:H76	S:S:G90	12.6844	3.18	No	No	0	0	9
169	S:S:G90	S:S:N114	11.2793	3.39	No	Yes	0	9	9
170	M:M:K58	S:S:N114	17.0609	2.8	Yes	Yes	6	0	9
171	M:M:H76	S:S:Q113	100	3.71	No	Yes	0	0	9
172	S:S:N114	S:S:Q113	11.5029	2.64	Yes	Yes	6	9	9
173	M:M:R86	S:S:Q113	100	3.5	Yes	Yes	6	0	9
174	M:M:K58	S:S:H140	11.6318	2.62	Yes	No	0	0	8
175	M:M:F60	M:M:R86	56.0861	12.83	No	Yes	0	0	0
176	M:M:F60	M:M:G84	53.2103	4.52	No	No	0	0	0
177	M:M:C78	M:M:G84	51.7724	1.96	No	No	0	0	0
178	M:M:C78	M:M:Y82	28.7626	2.69	No	Yes	12	0	0
179	M:M:F62	M:M:Y82	20.1341	13.41	Yes	Yes	12	0	0
180	M:M:C78	M:M:C93	21.5719	7.28	No	No	12	0	0
181	M:M:C93	M:M:F62	20.1339	4.19	No	Yes	12	0	0
182	M:M:F62	M:M:R64	37.392	9.62	Yes	No	12	0	0
183	M:M:R64	M:M:Y71	31.6394	8.23	No	Yes	12	0	0
184	M:M:R69	M:M:Y71	23.0106	7.2	No	Yes	12	0	0
185	M:M:R69	T:T:N196	20.1344	3.62	No	No	0	0	9
186	S:S:Q113	S:S:R135	100	5.84	Yes	Yes	6	9	9
187	S:S:R135	S:S:W159	100	13	Yes	Yes	6	9	9
188	M:M:F105	S:S:W159	100	13.03	Yes	Yes	6	0	9
189	M:M:F105	S:S:V205	100	2.62	Yes	Yes	6	0	9
190	S:S:T229	S:S:V205	31.0768	9.52	No	Yes	0	9	9
191	M:M:D108	S:S:T229	25.3571	5.78	No	No	0	0	9
192	M:M:D108	M:M:K107	19.7267	4.15	No	No	0	0	0
193	M:M:K107	M:M:Y83	14.0906	5.97	No	No	0	0	0
194	S:S:D137	S:S:Q113	100	10.44	Yes	Yes	6	9	9
195	S:S:D137	S:S:W159	100	3.35	Yes	Yes	6	9	9
196	M:M:R86	S:S:L186	43.6248	3.64	Yes	Yes	6	0	9
197	S:S:L186	S:S:N210	33.7533	4.12	Yes	Yes	0	9	9
198	M:M:F105	M:M:F109	100	5.36	Yes	Yes	6	0	0
199	M:M:F109	S:S:V204	100	6.55	Yes	Yes	6	0	9
200	S:S:E228	S:S:V204	100	5.7	No	Yes	0	9	9
201	S:S:E228	S:S:K251	100	5.4	No	Yes	0	9	9
202	M:M:R123	S:S:K251	100	4.95	No	Yes	0	0	9
203	M:M:I98	M:M:R123	100	2.51	No	No	0	0	0
204	S:S:H157	S:S:W159	100	5.29	Yes	Yes	6	9	9
205	M:M:F109	S:S:H157	100	4.53	Yes	Yes	6	0	9
206	S:S:V204	S:S:V205	100	3.21	Yes	Yes	6	9	9
207	M:M:C110	M:M:I98	100	3.27	Yes	No	17	0	0
208	M:M:C110	M:M:C124	100	3.64	Yes	No	17	0	0
209	M:M:C124	M:M:N100	92.8704	1.57	No	Yes	17	0	0
210	M:M:K114	M:M:N100	50.6567	4.2	Yes	Yes	17	0	0
211	M:M:F117	M:M:N100	25.3283	13.29	Yes	Yes	17	0	0
212	M:M:D102	M:M:K114	25.3284	2.77	No	Yes	0	0	0
213	M:M:D102	M:M:K112	16.8856	5.53	No	No	0	0	0
214	M:M:F109	S:S:Q180	11.2668	3.51	Yes	No	0	0	9
215	M:M:C110	M:M:C113	16.8855	5.46	Yes	No	17	0	0
216	M:M:R121	S:S:V204	100	3.92	No	Yes	0	0	9
217	M:M:H120	M:M:R121	100	10.16	Yes	No	0	0	0
218	M:M:C141	M:M:H120	84.4281	4.42	Yes	Yes	24	0	0
219	M:M:C141	M:M:Y118	25.3286	1.34	Yes	No	24	0	0
220	M:M:H120	M:M:P129	67.5425	4.58	Yes	Yes	24	0	0
221	M:M:F132	M:M:H120	25.3287	5.66	No	Yes	0	0	0
222	M:M:R121	S:S:N226	100	10.85	No	No	0	0	8
223	M:M:C128	M:M:P129	50.6569	3.77	No	Yes	24	0	0
224	M:M:C128	M:M:C141	50.657	7.28	No	Yes	24	0	0
225	M:M:F132	M:M:G131	16.8858	3.01	No	No	0	0	0
226	M:M:C128	M:M:P134	84.4283	1.88	No	No	0	0	0
227	M:M:A133	M:M:P134	67.5427	1.87	No	No	0	0	0
228	M:M:A133	M:M:D136	50.657	6.18	No	No	0	0	0
229	M:M:D136	M:M:E140	16.8857	5.2	No	No	0	0	0
230	E:E:H207	T:T:R208	100	4.51	Yes	No	0	9	9
231	R:R:I519	T:T:R208	100	2.51	No	No	0	4	9
232	R:R:I519	T:T:F60	100	6.28	No	No	0	4	8
233	E:E:T152	T:T:E95	100	7.06	No	Yes	0	9	8
234	E:E:R178	T:T:R204	100	10.66	Yes	Yes	0	9	9
235	E:E:Y118	T:T:R204	10.1949	3.09	Yes	Yes	29	9	9
236	E:E:E62	E:E:R204	65.9196	4.65	No	Yes	7	9	9
237	E:E:E62	E:E:T78	32.3817	4.23	No	No	7	9	9
238	E:E:E62	S:S:R460	32.3817	12.79	No	No	7	9	9
239	E:E:R204	T:T:Y118	66.282	3.09	Yes	Yes	7	9	9
240	S:S:R392	S:S:T416	30.07	7.76	Yes	No	0	6	4
241	S:S:N437	S:S:T416	41.6349	4.39	Yes	No	0	5	4
242	E:E:T78	S:S:N437	31.2254	2.92	No	Yes	7	9	5
243	S:S:N437	S:S:R460	31.2254	4.82	Yes	No	7	5	9
244	S:S:N437	S:S:N458	18.5049	2.72	Yes	Yes	7	5	4
245	E:E:L168	E:E:S86	19.2634	7.51	Yes	No	0	9	9
246	E:E:S86	E:E:Y182	20.3965	5.09	No	Yes	0	9	9
247	E:E:A88	E:E:L168	10.1987	3.15	No	Yes	0	9	9
248	E:E:C107	E:E:N109	13.7238	3.15	No	No	0	9	8
249	E:E:N109	E:E:N110	18.2984	9.54	No	No	0	8	9
250	E:E:E113	E:E:N110	27.444	7.89	No	No	0	9	9
251	E:E:E113	E:E:R149	31.9784	11.63	No	No	54	9	9
252	T:T:R202	T:T:V64	27.6046	5.23	Yes	Yes	29	9	9
253	E:E:I155	E:E:V121	13.742	3.07	Yes	No	0	9	9
254	E:E:I155	E:E:V183	22.9029	3.07	Yes	No	0	9	9
255	E:E:A188	E:E:V183	32.0636	3.39	No	No	0	9	9
256	E:E:A188	E:E:D157	36.6442	4.63	No	Yes	0	9	9
257	E:E:D157	E:E:K125	45.8047	5.53	Yes	Yes	3	9	9
258	E:E:K177	E:E:R178	100	2.48	No	Yes	0	9	9
259	E:E:K177	R:R:Q438	100	6.78	No	Yes	0	9	9
260	T:T:R178	T:T:T152	23.0039	9.06	Yes	No	0	9	9
261	E:E:H207	E:E:R208	100	6.77	Yes	No	0	9	9
262	E:E:R208	E:E:R211	100	4.26	No	No	0	9	8
263	E:E:Q212	E:E:R208	15.2815	7.01	No	No	0	8	9
264	E:E:R211	E:E:Y216	100	4.12	No	Yes	0	8	9
265	E:E:E215	E:E:Y216	100	11.22	Yes	Yes	9	9	9
266	E:E:Y216	T:T:Q212	100	3.38	Yes	Yes	9	9	8
267	E:E:E215	T:T:E215	100	7.61	Yes	Yes	9	9	9
268	E:E:E215	T:T:D218	100	3.9	Yes	Yes	9	9	9
269	T:T:D218	T:T:Q212	100	16.97	Yes	Yes	9	9	8
270	E:E:Y216	S:S:S778	91.7337	3.82	Yes	Yes	0	9	6
271	S:S:I781	S:S:S778	83.8521	3.1	Yes	Yes	0	8	6
272	E:E:M219	T:T:D218	21.3687	9.7	No	Yes	9	9	9
273	S:S:I781	T:T:F222	79.7508	6.28	Yes	Yes	9	8	9
274	R:R:I781	T:T:E215	58.8885	2.73	Yes	Yes	0	8	9
275	T:T:D218	T:T:M219	100	2.77	Yes	Yes	9	9	9
276	E:E:L223	T:T:F222	96.3821	7.31	No	Yes	0	9	9
277	E:E:L223	S:S:F789	96.0063	3.65	No	Yes	0	9	7
278	R:R:F789	R:R:V785	57.4926	5.24	Yes	No	0	7	7
279	R:R:F766	R:R:V785	57.6932	7.87	No	No	0	9	7
280	R:R:F766	R:R:I781	58.1552	2.51	No	Yes	0	9	8
281	R:R:F789	R:R:I788	100	2.51	Yes	No	0	7	7
282	R:R:I788	T:T:L223	100	5.71	No	Yes	0	7	9
283	T:T:L223	T:T:M219	100	4.24	Yes	Yes	9	9	9
284	E:E:F226	R:R:F789	100	3.22	No	Yes	0	9	7
285	E:E:F226	T:T:F226	100	21.43	No	Yes	0	9	9
286	E:E:S230	X:X:?1	50.8454	13.48	No	Yes	5	9	0
287	E:E:S230	T:T:F226	51.7944	2.64	No	Yes	5	9	9
288	W:W:?1	X:X:?1	51.528	30.28	Yes	Yes	5	0	0
289	T:T:F226	W:W:?1	100	6.07	Yes	Yes	5	9	0
290	R:R:L796	R:R:L800	66.3633	2.77	No	No	0	8	9
291	R:R:F804	R:R:L800	67.3246	10.96	No	No	0	9	9
292	R:R:F804	W:W:?1	68.2542	24.29	No	Yes	5	9	0
293	R:R:W751	W:W:?1	20.3386	6.81	Yes	Yes	5	8	0
294	E:E:L236	R:R:W751	17.4873	6.83	No	Yes	5	9	8
295	E:E:L236	R:R:F754	16.5286	3.65	No	Yes	0	9	8
296	R:R:M745	R:R:R643	25.9751	6.2	Yes	Yes	0	7	8
297	R:R:M745	R:R:N805	38.4778	2.8	Yes	No	0	7	8
298	R:R:H748	R:R:N805	39.4362	19.13	No	No	69	9	8
299	R:R:H748	R:R:L752	55.7874	3.86	No	No	0	9	9
300	R:R:L752	R:R:N797	56.7489	5.49	No	No	0	9	9
301	R:R:L796	R:R:N797	57.7104	5.49	No	No	0	8	9
302	R:R:E780	T:T:E215	100	5.07	Yes	Yes	9	8	9
303	R:R:E780	R:R:P779	100	11	Yes	No	9	8	8
304	R:R:F529	R:R:P779	100	4.33	No	No	0	8	8
305	R:R:F529	R:R:P697	100	2.89	No	Yes	0	8	7
306	R:R:L692	R:R:P697	100	3.28	Yes	Yes	13	7	7
307	R:R:L692	R:R:S690	100	4.5	Yes	No	0	7	8
308	R:R:P691	R:R:S690	100	5.34	Yes	No	0	9	8
309	R:R:P691	R:R:Y468	100	4.17	Yes	Yes	11	9	9
310	R:R:I610	R:R:Y468	100	6.04	No	Yes	0	7	9
311	R:R:I610	R:R:Y466	100	4.84	No	Yes	0	7	6
312	R:R:Q469	R:R:Y466	100	6.76	No	Yes	0	9	6
313	R:R:Q469	R:R:V464	100	7.16	No	No	0	9	7
314	R:R:P465	R:R:V464	100	3.53	No	No	0	9	7
315	R:R:N444	R:R:P465	100	3.26	No	No	0	9	9
316	R:R:L425	R:R:N444	100	12.36	No	No	0	9	9
317	R:R:I404	R:R:L425	100	2.85	Yes	No	0	7	9
318	R:R:I401	R:R:I404	100	2.94	Yes	Yes	0	8	7
319	R:R:I401	R:R:L396	100	2.85	Yes	Yes	0	8	9
320	R:R:L372	R:R:L396	100	2.77	Yes	Yes	0	8	9
321	R:R:L350	R:R:L372	100	2.77	Yes	Yes	0	9	8
322	R:R:L348	R:R:L350	100	4.15	No	Yes	0	9	9
323	R:R:L324	R:R:L348	100	4.15	No	No	0	9	9
324	R:R:L301	R:R:L324	100	4.15	No	No	0	9	9
325	R:R:I303	R:R:L301	100	4.28	Yes	No	0	8	9
326	R:R:I303	R:R:L279	100	4.28	Yes	No	0	8	8
327	R:R:I277	R:R:L279	100	4.28	Yes	No	0	8	8
328	R:R:F255	R:R:I277	100	2.51	Yes	Yes	2	9	8
329	R:R:F255	R:R:L253	100	6.09	Yes	Yes	2	9	9
330	R:R:L230	R:R:L253	100	4.15	Yes	Yes	0	9	9
331	R:R:L206	R:R:L230	100	4.15	No	Yes	0	9	9
332	R:R:L182	R:R:L206	100	4.15	Yes	No	0	8	9
333	R:R:L158	R:R:L182	100	4.15	Yes	Yes	0	9	8
334	R:R:L134	R:R:L158	100	2.77	Yes	Yes	8	9	9
335	R:R:L110	R:R:L134	100	4.15	Yes	Yes	8	9	9
336	R:R:L110	R:R:L86	100	2.77	Yes	No	8	9	8
337	R:R:L86	R:R:L88	100	4.15	No	Yes	0	8	9
338	R:R:I64	R:R:L88	100	5.71	No	Yes	0	6	9
339	R:R:I64	R:R:L62	100	5.71	No	No	0	6	5
340	R:R:L62	R:R:P52	100	3.28	No	No	0	5	8
341	R:R:C43	R:R:P52	100	3.77	No	No	0	8	8
342	R:R:C33	R:R:C43	100	7.28	No	No	0	9	8
343	R:R:T544	T:T:L223	100	4.42	No	Yes	9	9	9
344	R:R:T544	R:R:V545	100	3.17	No	No	0	9	8
345	R:R:L536	R:R:V545	100	4.47	Yes	No	0	5	8
346	R:R:L535	R:R:L536	100	4.15	Yes	Yes	11	9	5
347	R:R:L535	R:R:P691	100	3.28	Yes	Yes	11	9	9
348	R:R:L447	R:R:P465	100	3.28	No	No	0	7	9
349	R:R:L425	R:R:L447	100	5.54	No	No	0	9	7
350	R:R:L324	R:R:L326	100	4.15	No	Yes	0	9	7
351	R:R:I303	R:R:L326	100	2.85	Yes	Yes	0	8	7
352	R:R:L350	R:R:N353	100	5.49	Yes	Yes	0	9	9
353	R:R:N353	R:R:T329	100	8.77	Yes	No	19	9	8
354	R:R:L326	R:R:T329	100	2.95	Yes	No	19	7	8
355	R:R:L372	R:R:N375	100	4.12	Yes	Yes	0	8	9
356	R:R:N353	R:R:N375	100	2.72	Yes	Yes	19	9	9
357	R:R:I401	R:R:N423	100	9.91	Yes	No	0	8	9
358	R:R:N399	R:R:N423	100	5.45	No	No	0	9	9
359	R:R:N375	R:R:N399	100	4.09	Yes	No	19	9	9
360	R:R:I331	R:R:N353	100	8.5	Yes	Yes	19	8	9
361	R:R:I331	R:R:L326	100	4.28	Yes	Yes	19	8	7
362	R:R:F268	R:R:I277	100	2.51	Yes	Yes	2	9	8
363	R:R:F268	R:R:L253	100	3.65	Yes	Yes	2	9	9
364	R:R:L110	R:R:L112	100	5.54	Yes	Yes	0	9	9
365	R:R:L112	R:R:L88	100	4.15	Yes	Yes	0	9	9
366	R:R:L134	R:R:L136	100	11.07	Yes	No	0	9	9
367	R:R:L112	R:R:L136	100	4.15	Yes	No	0	9	9
368	R:R:I64	R:R:N67	100	9.91	No	Yes	0	6	9
369	R:R:L48	R:R:N67	100	5.49	No	Yes	0	8	9
370	R:R:K46	R:R:L48	100	9.87	No	No	0	4	8
371	R:R:C33	R:R:K46	100	4.85	No	No	0	9	4
372	R:R:L88	R:R:N91	100	6.87	Yes	No	0	9	9
373	R:R:N67	R:R:N91	100	6.81	Yes	No	59	9	9
374	R:R:C33	R:R:V41	100	3.42	No	Yes	0	9	7
375	R:R:D137	R:R:Q113	100	3.92	Yes	Yes	1	9	9
376	R:R:A89	R:R:Q113	91.3766	6.06	No	Yes	0	9	9
377	R:R:A89	R:R:S65	82.2381	3.42	No	No	0	9	9
378	R:R:S44	R:R:S65	45.6892	3.26	Yes	No	42	7	9
379	R:R:D42	R:R:S44	18.2736	7.36	No	Yes	42	9	7
380	R:R:D63	R:R:S65	27.4104	4.42	Yes	No	42	9	9
381	R:R:D42	R:R:D63	54.8242	6.65	No	Yes	42	9	9
382	R:R:Q113	R:R:T111	45.6839	7.09	Yes	No	1	9	9
383	R:R:Q87	R:R:T111	73.1058	7.09	No	No	0	8	9
384	R:R:D63	R:R:Q87	54.8306	7.83	Yes	No	0	9	8
385	R:R:R135	R:R:T111	45.6972	9.06	Yes	No	1	9	9
386	R:R:D42	R:R:S34	36.5489	4.42	No	No	0	9	4
387	R:R:C35	R:R:V41	100	3.42	No	Yes	0	9	7
388	R:R:H157	R:R:S133	100	5.58	Yes	No	0	9	9
389	R:R:S133	R:R:V109	100	6.46	No	No	0	9	8
390	R:R:K108	R:R:V109	100	3.04	No	No	0	8	8
391	R:R:E84	R:R:K108	100	4.05	No	No	0	6	8
392	R:R:E84	R:R:E85	100	13.95	No	No	0	6	8
393	R:R:E85	R:R:R40	100	5.82	No	Yes	58	8	3
394	R:R:D38	R:R:R40	54.8212	14.29	No	Yes	0	6	3
395	R:R:Q132	R:R:R156	100	8.18	No	Yes	0	8	9
396	R:R:K108	R:R:Q132	100	13.56	No	No	0	8	8
397	R:R:E84	R:R:Q60	100	16.57	No	No	0	6	5
398	R:R:Q60	R:R:R39	100	3.5	No	No	0	5	7
399	R:R:F58	R:R:R39	100	13.9	No	No	0	6	7
400	R:R:A61	R:R:E85	54.8212	4.53	No	No	58	4	8
401	R:R:L55	R:R:V41	100	10.43	No	Yes	57	6	7
402	R:R:T59	R:R:V41	100	6.35	No	Yes	57	8	7
403	R:R:M66	R:R:S44	18.2802	3.07	No	Yes	0	9	7
404	R:R:L88	R:R:L93	100	4.15	Yes	No	0	9	9
405	R:R:I96	R:R:L93	100	2.85	Yes	No	0	9	9
406	R:R:I96	R:R:L72	100	7.14	Yes	Yes	0	9	7
407	R:R:L72	R:R:P73	100	4.93	Yes	No	0	7	5
408	R:R:A76	R:R:P73	100	5.61	No	No	0	4	5
409	R:R:L112	R:R:N115	100	2.75	Yes	Yes	0	9	9
410	R:R:L93	R:R:N115	100	6.87	No	Yes	0	9	9
411	R:R:L136	R:R:N139	100	2.75	No	Yes	0	9	9
412	R:R:N115	R:R:N139	100	5.45	Yes	Yes	61	9	9
413	R:R:F255	R:R:N258	100	6.04	Yes	Yes	2	9	9
414	R:R:L237	R:R:N258	100	4.12	Yes	Yes	2	8	9
415	R:R:I213	R:R:L237	100	2.85	Yes	Yes	2	9	8
416	R:R:I213	R:R:N211	100	7.08	Yes	Yes	2	9	9
417	R:R:N187	R:R:N211	100	2.72	No	Yes	0	9	9
418	R:R:N163	R:R:N187	100	4.09	No	No	0	9	9
419	R:R:I141	R:R:N163	100	11.33	Yes	No	0	9	9
420	R:R:I141	R:R:N139	100	2.83	Yes	Yes	0	9	9
421	R:R:L237	R:R:N235	100	2.75	Yes	Yes	2	8	9
422	R:R:N211	R:R:N235	100	5.45	Yes	Yes	2	9	9
423	R:R:L165	R:R:N187	100	6.87	No	No	0	9	9
424	R:R:I141	R:R:L165	100	2.85	Yes	No	0	9	9
425	R:R:F80	R:R:L62	100	3.65	Yes	No	0	7	5
426	R:R:F77	R:R:F80	100	3.22	No	Yes	0	7	7
427	R:R:F77	R:R:V51	100	3.93	No	No	0	7	5
428	R:R:F77	R:R:L72	100	7.31	No	Yes	0	7	7
429	R:R:I69	R:R:N91	83.7559	8.5	No	No	59	7	9
430	R:R:F149	R:R:L158	100	3.65	Yes	Yes	8	9	9
431	R:R:F149	R:R:S148	100	11.89	Yes	No	8	9	8
432	R:R:P145	R:R:S148	100	3.56	Yes	No	8	9	8
433	R:R:P145	R:R:S122	100	5.34	Yes	No	8	9	5
434	R:R:E123	R:R:S122	100	2.87	No	No	0	5	5
435	R:R:E123	R:R:P98	100	3.14	No	No	0	5	4
436	R:R:H97	R:R:P98	100	12.2	Yes	No	0	8	4
437	R:R:F95	R:R:H97	100	6.79	No	Yes	0	3	8
438	R:R:F95	R:R:Q71	83.7596	3.51	No	No	0	3	4
439	R:R:A100	R:R:L72	100	3.15	No	Yes	0	8	7
440	R:R:E74	R:R:H97	83.7595	29.54	No	Yes	38	5	8
441	R:R:D75	R:R:E74	55.8397	12.99	Yes	No	38	4	5
442	R:R:H97	R:R:K99	100	5.24	Yes	Yes	38	8	3
443	R:R:D75	R:R:K99	55.8397	4.15	Yes	Yes	38	4	3
444	R:R:K99	R:R:S102	27.9199	7.65	Yes	No	38	3	5
445	R:R:F80	R:R:N79	83.7564	10.87	Yes	No	0	7	4
446	R:R:F80	R:R:L83	100	3.65	Yes	No	0	7	9
447	R:R:A57	R:R:F80	100	1.39	No	Yes	0	4	7
448	R:R:A57	R:R:F82	100	1.39	No	No	0	4	5
449	R:R:L104	R:R:L83	100	2.77	No	No	0	9	9
450	R:R:L104	R:R:P81	83.7564	1.64	No	No	0	9	5
451	R:R:F82	R:R:P81	83.7564	5.78	No	No	0	5	5
452	R:R:L107	R:R:L110	27.9186	2.77	No	Yes	8	9	9
453	R:R:H140	R:R:Q116	27.4149	6.18	No	No	0	8	6
454	R:R:I96	R:R:L101	100	4.28	Yes	No	60	9	7
455	R:R:A124	R:R:I96	100	4.87	No	Yes	60	8	9
456	R:R:L131	R:R:L134	83.7553	2.77	Yes	Yes	8	9	9
457	R:R:L117	R:R:N139	83.7536	9.61	No	Yes	61	8	9
458	R:R:P145	R:R:T119	100	1.75	Yes	No	0	9	5
459	R:R:S143	R:R:T119	100	4.8	No	No	0	3	5
460	R:R:I125	R:R:L134	83.7563	2.85	No	Yes	0	5	9
461	R:R:I125	R:R:P121	27.919	3.39	No	No	0	5	8
462	R:R:F149	R:R:V120	83.7608	2.62	Yes	Yes	0	9	7
463	R:R:P121	R:R:V120	27.9191	3.53	No	Yes	0	8	7
464	R:R:V120	R:R:V144	27.9392	6.41	Yes	Yes	0	7	9
465	R:R:S148	R:R:V144	27.9236	3.23	No	Yes	8	8	9
466	R:R:D147	R:R:P145	83.7578	3.22	No	Yes	8	3	9
467	R:R:E123	R:R:R126	27.919	5.82	No	No	0	5	4
468	R:R:D147	R:R:E150	55.8381	3.9	No	No	0	3	4
469	R:R:E150	R:R:R126	27.92	6.98	No	No	0	4	4
470	R:R:I125	R:R:L152	27.9187	2.85	No	No	0	5	8
471	R:R:L131	R:R:L152	27.9199	2.77	Yes	No	0	9	8
472	R:R:L128	R:R:L131	27.9193	2.77	No	Yes	0	9	9
473	R:R:S143	R:R:T142	100	3.2	No	No	0	3	6
474	R:R:F240	R:R:F255	100	6.43	Yes	Yes	2	9	9
475	R:R:F240	R:R:P241	100	8.67	Yes	Yes	2	9	9
476	R:R:L216	R:R:P241	100	3.28	Yes	Yes	2	6	9
477	R:R:I192	R:R:L216	100	2.85	Yes	Yes	2	8	6
478	R:R:I192	R:R:P193	100	3.39	Yes	No	0	8	9
479	R:R:P193	R:R:V168	100	3.53	No	Yes	0	9	8
480	R:R:P169	R:R:V168	100	3.53	No	Yes	0	9	8
481	R:R:P169	R:R:P172	100	5.84	No	Yes	0	9	9
482	R:R:F240	R:R:F268	100	3.22	Yes	Yes	2	9	9
483	R:R:L216	R:R:L237	100	2.77	Yes	Yes	2	6	8
484	R:R:I192	R:R:I213	100	2.94	Yes	Yes	2	8	9
485	R:R:F197	R:R:I192	100	3.77	Yes	Yes	0	9	8
486	R:R:F197	R:R:V168	100	3.93	Yes	Yes	0	9	8
487	R:R:F197	R:R:L182	100	3.65	Yes	Yes	0	9	8
488	R:R:I189	R:R:N211	100	7.08	No	Yes	0	9	9
489	R:R:I189	R:R:V168	100	3.07	No	Yes	0	9	8
490	R:R:E146	R:R:P172	100	3.14	No	Yes	8	4	9
491	R:R:H171	R:R:P172	100	4.58	Yes	Yes	8	1	9
492	R:R:F149	R:R:L176	100	6.09	Yes	Yes	0	9	9
493	R:R:H171	R:R:N175	100	3.83	Yes	No	8	1	4
494	R:R:L155	R:R:L176	27.9189	5.54	No	Yes	0	9	9
495	R:R:Q154	R:R:R156	54.822	3.5	No	Yes	0	8	9
496	R:R:Q154	R:R:V153	27.411	2.87	No	No	0	8	3
497	R:R:L158	R:R:L160	27.9317	2.77	Yes	No	0	9	9
498	R:R:L182	R:R:L184	55.8479	4.15	Yes	Yes	0	8	9
499	R:R:L160	R:R:L184	97.725	4.15	No	Yes	0	9	9
500	R:R:L206	R:R:L208	83.7635	9.69	No	Yes	0	9	9
501	R:R:L184	R:R:L208	100	4.15	Yes	Yes	0	9	9
502	R:R:L230	R:R:L232	100	4.15	Yes	No	0	9	9
503	R:R:L208	R:R:L232	83.757	2.77	Yes	No	0	9	9
504	R:R:I213	R:R:L208	41.9012	2.85	Yes	Yes	2	9	9
505	R:R:A185	R:R:D161	91.3726	4.63	No	Yes	0	9	9
506	R:R:S164	R:R:T142	100	1.6	No	No	0	5	6
507	R:R:K188	R:R:S164	83.7596	4.59	No	No	0	4	5
508	R:R:K188	R:R:T166	27.9199	4.5	No	No	0	4	6
509	R:R:F197	R:R:L200	100	4.87	Yes	No	0	9	9
510	R:R:L173	R:R:L200	83.7539	2.77	No	No	0	9	9
511	R:R:H171	R:R:S174	100	6.97	Yes	No	8	1	5
512	R:R:L179	R:R:L200	83.757	5.54	No	No	0	9	9
513	R:R:L176	R:R:P177	83.759	1.64	Yes	No	0	9	4
514	R:R:N199	R:R:P177	27.9197	4.89	No	No	0	9	4
515	R:R:A185	R:R:H209	73.0996	5.85	No	Yes	0	9	9
516	R:R:K188	R:R:K212	27.9199	2.87	No	No	0	4	5
517	R:R:C220	R:R:L216	100	4.76	Yes	Yes	2	5	6
518	R:R:F221	R:R:L230	100	6.09	Yes	Yes	0	9	9
519	R:R:C220	R:R:F221	100	11.17	Yes	Yes	0	5	9
520	R:R:I277	R:R:L274	100	8.56	Yes	Yes	2	8	9
521	R:R:L250	R:R:L274	100	4.15	No	Yes	2	9	9
522	R:R:L247	R:R:L250	100	5.54	No	No	0	9	9
523	R:R:F221	R:R:L247	100	3.65	Yes	No	0	9	9
524	R:R:A196	R:R:P193	100	3.74	No	No	0	9	9
525	R:R:A196	R:R:F197	100	2.77	No	Yes	0	9	9
526	R:R:C220	R:R:S217	100	1.72	Yes	No	0	5	6
527	R:R:D194	R:R:S217	100	11.78	No	No	0	8	6
528	R:R:D194	R:R:H219	100	2.52	No	Yes	0	8	5
529	R:R:F195	R:R:H219	100	7.92	No	Yes	62	2	5
530	R:R:F195	R:R:T198	83.7543	3.89	No	No	0	2	4
531	R:R:D222	R:R:H219	100	13.87	No	Yes	62	4	5
532	R:R:F221	R:R:L224	100	3.65	Yes	No	0	9	9
533	R:R:L203	R:R:L224	83.7564	4.15	No	No	0	9	9
534	R:R:L203	R:R:L227	41.8782	2.77	No	No	0	9	9
535	R:R:E228	R:R:V204	100	5.7	No	Yes	0	9	9
536	R:R:D231	R:R:H207	18.2788	15.13	Yes	Yes	1	9	9
537	R:R:D231	R:R:H209	27.4124	2.52	Yes	Yes	1	9	9
538	R:R:H209	R:R:N233	54.827	5.1	Yes	Yes	1	9	9
539	R:R:N210	R:R:Y234	45.6857	11.63	Yes	No	1	9	6
540	R:R:H219	R:R:Q218	83.7543	13.6	Yes	No	0	5	3
541	R:R:A246	R:R:D222	83.7543	3.09	No	No	0	5	4
542	R:R:L247	R:R:P248	27.9227	1.64	No	No	0	9	4
543	R:R:D225	R:R:P248	13.9613	3.22	No	No	0	4	4
544	R:R:H256	R:R:Y234	27.4098	6.53	Yes	No	1	9	6
545	R:R:F255	R:R:I260	83.759	2.51	Yes	Yes	2	9	9
546	R:R:F240	R:R:I263	27.9222	2.51	Yes	No	2	9	9
547	R:R:F240	R:R:P264	27.9218	8.67	Yes	No	2	9	9
548	R:R:A267	R:R:F240	27.9218	4.16	No	Yes	2	9	9
549	R:R:I244	R:R:L253	27.9408	5.71	No	Yes	0	8	9
550	R:R:F268	R:R:N271	100	3.62	Yes	Yes	2	9	9
551	R:R:I244	R:R:N271	27.9528	2.83	No	Yes	0	8	9
552	R:R:L274	R:R:N271	100	4.12	Yes	Yes	2	9	9
553	R:R:K251	R:R:R275	91.3714	3.71	Yes	No	0	9	5
554	R:R:H256	R:R:Y280	18.2789	27.22	Yes	No	0	9	7
555	R:R:N258	R:R:N282	55.8836	8.17	Yes	Yes	2	9	9
556	R:R:I260	R:R:N282	55.8399	4.25	Yes	Yes	2	9	9
557	R:R:I260	R:R:L284	13.9615	2.85	Yes	No	2	9	8
558	R:R:I303	R:R:V287	100	3.07	Yes	No	0	8	9
559	R:R:G288	R:R:V287	69.8186	1.84	No	No	0	9	9
560	R:R:D265	R:R:G288	13.9637	5.03	No	No	0	8	9
561	R:R:N271	R:R:P272	100	1.63	Yes	No	0	9	8
562	R:R:L273	R:R:P272	27.9215	4.93	No	No	0	6	8
563	R:R:R275	R:R:T276	36.5486	5.17	No	No	0	5	8
564	R:R:D297	R:R:R275	36.5486	11.91	No	No	0	5	5
565	R:R:H278	R:R:T276	18.2743	5.48	No	No	0	8	8
566	R:R:F286	R:R:G288	41.8912	6.02	No	No	0	4	9
567	R:R:F286	R:R:S285	27.9275	1.32	No	No	0	4	8
568	R:R:M308	R:R:S285	13.9637	3.07	No	No	0	4	8
569	R:R:N294	R:R:P272	100	1.63	No	No	0	6	8
570	R:R:H293	R:R:N294	100	2.55	Yes	No	0	7	6
571	R:R:H293	R:R:N314	83.7646	8.93	Yes	No	63	7	7
572	R:R:N289	R:R:N314	55.8431	6.81	No	No	0	4	7
573	R:R:N289	R:R:Q311	27.9215	10.56	No	No	0	4	4
574	R:R:H293	R:R:S290	27.9215	5.58	Yes	No	0	7	8
575	R:R:L462	R:R:V464	100	4.47	No	No	0	7	7
576	R:R:F473	R:R:L462	100	3.65	Yes	No	0	8	7
577	R:R:F456	R:R:F473	100	4.29	Yes	Yes	0	5	8
578	R:R:F456	R:R:L433	88.6042	4.87	Yes	Yes	0	5	9
579	R:R:L418	R:R:L433	42.4175	2.77	Yes	Yes	23	9	9
580	R:R:I415	R:R:L418	80.2478	2.85	Yes	Yes	23	7	9
581	R:R:I415	R:R:L391	100	2.85	Yes	Yes	0	7	9
582	R:R:I370	R:R:L391	74.7441	2.85	Yes	Yes	0	7	9
583	R:R:I370	R:R:L367	91.998	5.71	Yes	No	0	7	7
584	R:R:L345	R:R:L367	100	4.15	No	No	0	9	7
585	R:R:L321	R:R:L345	41.942	2.77	No	No	32	8	9
586	R:R:L321	R:R:T318	31.4806	4.42	No	Yes	32	8	8
587	R:R:L295	R:R:T318	10.552	2.95	No	Yes	32	9	8
588	R:R:L441	R:R:N444	87.217	2.75	No	No	0	8	9
589	R:R:L439	R:R:L441	83.771	6.92	Yes	No	23	8	8
590	R:R:L418	R:R:L439	42.2483	4.15	Yes	Yes	23	9	8
591	R:R:L433	R:R:L436	40.9956	5.54	Yes	Yes	23	9	8
592	R:R:I415	R:R:L436	100	2.85	Yes	Yes	23	7	8
593	R:R:F456	R:R:L459	41.8674	7.31	Yes	No	0	5	7
594	R:R:L436	R:R:L459	41.0697	2.77	Yes	No	0	8	7
595	R:R:L436	R:R:L439	40.995	4.15	Yes	Yes	23	8	8
596	R:R:I370	R:R:L372	30.7008	4.28	Yes	Yes	0	7	8
597	R:R:L388	R:R:L391	100	6.92	Yes	Yes	0	8	9
598	R:R:L367	R:R:L388	65.9269	2.77	No	Yes	0	7	8
599	R:R:H293	R:R:T316	27.9215	2.74	Yes	No	63	7	5
600	R:R:L298	R:R:T318	10.4672	2.95	No	Yes	32	9	8
601	R:R:D297	R:R:S296	18.2743	2.94	No	No	0	5	9
602	R:R:K440	R:R:Q438	100	10.85	Yes	Yes	30	8	9
603	R:R:D419	R:R:K440	100	20.74	No	Yes	0	9	8
604	R:R:D419	R:R:S421	100	5.89	No	No	0	9	7
605	R:R:F422	R:R:S421	100	10.57	Yes	No	43	4	7
606	R:R:F422	R:R:R398	100	9.62	Yes	No	0	4	5
607	R:R:R374	R:R:R398	100	8.53	No	No	0	8	5
608	R:R:R374	R:R:Y352	96.1861	19.55	No	No	0	8	7
609	R:R:S351	R:R:Y352	91.6059	8.9	No	No	0	9	7
610	R:R:S351	R:R:T327	59.5439	4.8	No	Yes	31	9	9
611	R:R:R304	R:R:T327	22.9016	14.23	No	Yes	31	8	9
612	R:R:R304	R:R:V302	18.3213	5.23	No	No	31	8	7
613	R:R:S300	R:R:V302	68.7047	3.23	No	No	0	9	7
614	R:R:T325	R:R:T327	22.9016	3.14	Yes	Yes	31	8	9
615	R:R:T325	R:R:V302	73.2849	9.52	Yes	No	31	8	7
616	R:R:D349	R:R:S351	27.4818	2.94	Yes	No	31	8	9
617	R:R:D349	R:R:T325	68.7045	7.23	Yes	Yes	31	8	8
618	R:R:Q373	R:R:R374	36.6423	9.35	No	No	0	8	8
619	R:R:Q373	R:R:S371	64.1242	5.78	No	No	0	8	6
620	R:R:D349	R:R:S371	54.9636	4.42	Yes	No	0	8	6
621	R:R:R398	R:R:S397	41.2226	3.95	No	No	0	5	8
622	R:R:Q373	R:R:S397	36.6424	5.78	No	No	0	8	8
623	R:R:S300	R:R:S323	45.8031	3.26	No	No	0	9	7
624	R:R:F312	R:R:I331	10.4683	2.51	Yes	Yes	19	8	8
625	R:R:L345	R:R:Q342	94.2776	3.99	No	Yes	32	9	8
626	R:R:L315	R:R:Q342	10.5846	2.66	No	Yes	0	9	8
627	R:R:E341	R:R:Q342	62.8346	6.37	No	Yes	0	5	8
628	R:R:E341	R:R:V319	41.8898	2.85	No	No	0	5	4
629	R:R:H320	R:R:V319	20.9449	4.15	No	No	0	7	4
630	R:R:H320	R:R:M344	10.4725	6.57	No	No	0	7	4
631	R:R:N417	R:R:Q438	50.3815	17.17	No	Yes	30	7	9
632	R:R:I393	R:R:N417	45.8018	2.83	No	No	0	4	7
633	R:R:E369	R:R:I393	36.6438	2.73	No	No	0	7	4
634	R:R:E368	R:R:E369	32.0634	10.15	No	No	0	7	7
635	R:R:E368	R:R:R346	13.7415	6.98	No	No	0	7	7
636	R:R:S323	R:R:T347	22.9016	4.8	No	No	0	7	6
637	R:R:L338	R:R:Q342	10.4725	3.99	No	Yes	0	5	8
638	R:R:G387	R:R:L388	48.792	1.71	No	Yes	0	5	8
639	R:R:G387	R:R:H365	31.0496	3.18	No	No	0	5	3
640	R:R:G363	R:R:H365	22.1783	4.77	Yes	No	0	4	3
641	R:R:E341	R:R:Q340	10.4725	5.1	No	No	0	5	4
642	R:R:E368	R:R:R392	13.7415	8.14	No	No	0	7	6
643	R:R:I404	R:R:P429	12.5116	6.77	Yes	No	0	7	9
644	R:R:P429	R:R:S406	10.7243	1.78	No	No	0	9	3
645	R:R:G387	R:R:T411	13.307	1.82	No	No	0	5	4
646	T:T:T78	T:T:V64	46.0545	3.17	Yes	Yes	0	9	9
647	R:R:N437	T:T:T78	55.1344	2.92	No	Yes	0	5	9
648	R:R:N437	T:T:Y77	41.3796	6.98	No	Yes	66	5	6
649	R:R:N458	T:T:Y77	34.387	5.81	No	Yes	0	4	6
650	R:R:K440	R:R:S463	27.4829	3.06	Yes	No	30	8	8
651	R:R:N458	R:R:V457	20.6322	2.96	No	No	0	4	4
652	R:R:P524	R:R:S463	18.322	3.56	No	No	30	9	8
653	R:R:E613	R:R:P691	13.9514	3.14	Yes	Yes	11	9	9
654	R:R:C522	R:R:P524	13.7415	1.88	No	No	0	9	9
655	R:R:I548	R:R:V545	55.1228	3.07	No	No	0	7	8
656	R:R:I548	R:R:P791	47.102	5.08	No	Yes	0	7	9
657	R:R:M587	R:R:P791	20.7018	3.35	Yes	Yes	67	6	9
658	R:R:A794	R:R:M587	10.7007	3.22	No	Yes	0	8	6
659	R:R:A794	R:R:N584	10.0312	3.13	No	Yes	0	8	9
660	R:R:H748	R:R:Y801	15.3897	9.8	No	Yes	69	9	9
661	R:R:F808	R:R:Y801	13.4691	6.19	Yes	Yes	0	7	9
662	R:R:E642	R:R:R643	12.5072	15.12	Yes	Yes	33	8	8
663	R:R:F790	R:R:P791	22.3896	4.33	No	Yes	67	5	9
664	R:R:F696	R:R:P695	11.7135	5.78	No	Yes	13	7	9
665	R:R:F790	R:R:S629	21.727	5.28	No	No	0	5	8
666	R:R:E630	R:R:S629	21.0636	5.75	Yes	No	0	8	8
667	R:R:E630	R:R:F634	11.5325	8.16	Yes	Yes	10	8	7
668	S:S:D225	S:S:N226	100	2.69	No	No	0	4	8
669	S:S:D225	S:S:P248	100	12.88	No	No	0	4	4
670	S:S:L247	S:S:P248	100	1.64	Yes	No	0	9	4
671	S:S:F221	S:S:L247	100	3.65	No	Yes	0	9	9
672	S:S:F221	S:S:L230	100	4.87	No	No	0	9	9
673	S:S:L206	S:S:L230	100	4.15	Yes	No	0	9	9
674	S:S:L182	S:S:L206	100	4.15	Yes	Yes	0	8	9
675	S:S:L158	S:S:L182	100	4.15	No	Yes	0	9	8
676	S:S:L134	S:S:L158	100	4.15	Yes	No	0	9	9
677	S:S:L110	S:S:L134	100	4.15	Yes	Yes	0	9	9
678	S:S:L110	S:S:L86	100	4.15	Yes	Yes	0	9	8
679	S:S:L62	S:S:L86	100	4.15	No	Yes	0	5	8
680	S:S:I64	S:S:L62	100	8.56	Yes	No	0	6	5
681	S:S:C43	S:S:I64	100	3.27	No	Yes	25	8	6
682	S:S:C33	S:S:C43	100	7.28	No	No	25	9	8
683	S:S:L227	S:S:L247	100	5.54	No	Yes	0	9	9
684	S:S:L203	S:S:L227	100	2.77	Yes	No	73	9	9
685	S:S:L203	S:S:L206	100	2.77	Yes	Yes	0	9	9
686	S:S:L86	S:S:L88	100	5.54	Yes	No	0	8	9
687	S:S:I64	S:S:L88	100	4.28	Yes	No	0	6	9
688	S:S:L110	S:S:L112	100	6.92	Yes	No	0	9	9
689	S:S:L112	S:S:L88	100	4.15	No	No	0	9	9
690	S:S:L134	S:S:L136	100	6.92	Yes	Yes	0	9	9
691	S:S:L112	S:S:L136	100	4.15	No	Yes	0	9	9
692	S:S:L182	S:S:L184	100	6.92	Yes	Yes	0	8	9
693	S:S:L160	S:S:L184	100	4.15	No	Yes	0	9	9
694	S:S:L136	S:S:L160	100	4.15	Yes	No	0	9	9
695	S:S:L206	S:S:L208	100	5.54	Yes	Yes	0	9	9
696	S:S:L184	S:S:L208	100	4.15	Yes	Yes	0	9	9
697	S:S:I64	S:S:P52	100	3.39	Yes	Yes	25	6	8
698	S:S:C33	S:S:P52	100	3.77	No	Yes	25	9	8
699	S:S:F77	S:S:L86	100	4.87	Yes	Yes	0	7	8
700	S:S:F77	S:S:V51	100	5.24	Yes	No	0	7	5
701	S:S:P52	S:S:V51	67.5337	3.53	Yes	No	0	8	5
702	S:S:R135	S:S:T111	32.4951	7.76	Yes	No	0	9	9
703	S:S:Q87	S:S:T111	31.0726	7.09	No	No	0	8	9
704	S:S:E85	S:S:Q87	19.7344	3.82	Yes	No	0	8	8
705	S:S:F77	S:S:F80	100	6.43	Yes	Yes	0	7	7
706	S:S:F80	S:S:L55	67.5374	2.44	Yes	No	0	7	6
707	S:S:L55	S:S:V41	33.7687	11.92	No	No	72	6	7
708	S:S:L55	S:S:T59	16.8843	8.84	No	No	72	6	8
709	S:S:L48	S:S:P52	100	3.28	No	Yes	0	8	8
710	S:S:K46	S:S:L48	100	2.82	No	No	0	4	8
711	S:S:I64	S:S:N67	100	7.08	Yes	Yes	25	6	9
712	S:S:L48	S:S:N67	100	9.61	No	Yes	0	8	9
713	S:S:A76	S:S:V51	16.8846	3.39	No	No	0	4	5
714	S:S:I64	S:S:N91	100	4.25	Yes	No	25	6	9
715	S:S:I69	S:S:N67	100	2.83	No	Yes	25	7	9
716	S:S:I69	S:S:N91	100	8.5	No	No	25	7	9
717	S:S:L200	S:S:L203	100	5.54	No	Yes	0	9	9
718	S:S:L179	S:S:L200	100	5.54	No	No	0	9	9
719	S:S:L176	S:S:L179	100	6.92	Yes	No	0	9	9
720	S:S:F149	S:S:L176	100	3.65	Yes	Yes	0	9	9
721	S:S:F149	S:S:S148	100	10.57	Yes	No	0	9	8
722	S:S:P145	S:S:S148	100	3.56	Yes	No	14	9	8
723	S:S:P145	S:S:S122	100	10.69	Yes	No	0	9	5
724	S:S:D147	S:S:S122	100	4.42	No	No	0	3	5
725	S:S:D147	S:S:E123	100	3.9	No	No	0	3	5
726	S:S:E123	S:S:P98	100	1.57	No	No	0	5	4
727	S:S:H97	S:S:P98	100	12.2	Yes	No	0	8	4
728	S:S:F95	S:S:H97	33.8417	5.66	No	Yes	0	3	8
729	S:S:F95	S:S:Q71	16.9209	7.03	No	No	0	3	4
730	S:S:F77	S:S:L72	100	4.87	Yes	No	0	7	7
731	S:S:L72	S:S:P73	16.8842	3.28	No	No	0	7	5
732	S:S:I96	S:S:L72	67.5374	8.56	Yes	No	0	9	7
733	S:S:E74	S:S:H97	16.9208	25.85	No	Yes	45	5	8
734	S:S:H97	S:S:K99	67.6831	5.24	Yes	Yes	45	8	3
735	S:S:F80	S:S:N79	16.8844	21.75	Yes	No	0	7	4
736	S:S:F80	S:S:P81	100	1.44	Yes	No	0	7	5
737	S:S:F82	S:S:P81	50.653	4.33	No	No	0	5	5
738	S:S:E106	S:S:F82	16.8844	7	No	No	0	7	5
739	S:S:L104	S:S:P81	33.7687	1.64	No	No	0	9	5
740	S:S:L104	S:S:L83	16.8844	4.15	No	No	0	9	9
741	S:S:L136	S:S:N139	100	4.12	Yes	No	14	9	9
742	S:S:L117	S:S:N139	100	6.87	No	No	0	8	9
743	S:S:L117	S:S:L93	100	2.77	No	No	0	8	9
744	S:S:F149	S:S:V120	59.0984	2.62	Yes	Yes	0	9	7
745	S:S:P121	S:S:V120	33.7912	3.53	No	Yes	0	8	7
746	S:S:L117	S:S:P121	25.3149	3.28	No	No	0	8	8
747	S:S:L93	S:S:N115	59.0896	6.87	No	No	0	9	9
748	S:S:I96	S:S:L101	16.8844	4.28	Yes	No	0	9	7
749	S:S:A124	S:S:I96	16.8844	4.87	No	Yes	0	8	9
750	S:S:K99	S:S:S102	50.7624	4.59	Yes	No	0	3	5
751	S:S:L107	S:S:L110	16.8843	2.77	No	Yes	0	9	9
752	S:S:L110	S:S:L131	33.7694	5.54	Yes	No	0	9	9
753	S:S:L155	S:S:L176	33.7692	4.15	No	Yes	0	9	9
754	S:S:L152	S:S:L155	25.3231	4.15	No	No	0	8	9
755	S:S:L131	S:S:L152	16.8771	2.77	No	No	0	9	8
756	S:S:P145	S:S:T119	33.8417	3.5	Yes	No	0	9	5
757	S:S:S143	S:S:T119	25.3813	4.8	No	No	0	3	5
758	S:S:I141	S:S:L136	50.6536	2.85	Yes	Yes	14	9	9
759	S:S:L160	S:S:N163	67.537	2.75	No	Yes	0	9	9
760	S:S:I141	S:S:N163	67.5375	8.5	Yes	Yes	14	9	9
761	S:S:L184	S:S:N187	100	4.12	Yes	No	0	9	9
762	S:S:N163	S:S:N187	67.5372	6.81	Yes	No	14	9	9
763	S:S:L165	S:S:N187	67.5366	10.98	No	No	14	9	9
764	S:S:I141	S:S:L165	33.7696	2.85	Yes	No	14	9	9
765	S:S:L173	S:S:L182	100	4.15	No	Yes	0	9	8
766	S:S:L173	S:S:P169	84.6069	4.93	No	No	0	9	9
767	S:S:P169	S:S:P172	67.7239	5.84	No	No	0	9	9
768	S:S:P172	S:S:V144	17.0785	3.53	No	Yes	0	9	9
769	S:S:D147	S:S:E150	25.3812	3.9	No	No	0	3	4
770	S:S:L128	S:S:L131	25.3223	2.77	No	No	0	9	9
771	S:S:S143	S:S:T142	16.9209	3.2	No	No	0	3	6
772	S:S:G103	S:S:S102	42.3021	1.86	No	No	0	8	5
773	S:S:G103	S:S:K105	33.8417	1.74	No	No	0	8	3
774	S:S:K105	S:S:S129	25.3813	1.53	No	No	0	3	4
775	S:S:S129	S:S:V153	16.9209	1.62	No	No	0	4	3
776	S:S:C220	S:S:F221	100	11.17	Yes	No	0	5	9
777	S:S:C220	S:S:I192	50.6549	3.27	Yes	Yes	20	5	8
778	S:S:F197	S:S:I192	25.3643	2.51	Yes	Yes	20	9	8
779	S:S:F197	S:S:L200	25.3238	3.65	Yes	No	0	9	9
780	S:S:H171	S:S:P172	33.7687	4.58	No	No	0	1	9
781	S:S:H171	S:S:S174	16.8844	4.18	No	No	0	1	5
782	S:S:L176	S:S:P177	25.3418	1.64	Yes	No	0	9	4
783	S:S:C220	S:S:L216	67.5292	3.17	Yes	Yes	20	5	6
784	S:S:I213	S:S:L216	42.1975	4.28	Yes	Yes	20	9	6
785	S:S:I213	S:S:N211	16.8827	5.66	Yes	Yes	20	9	9
786	S:S:I189	S:S:N211	25.3205	9.91	No	Yes	0	9	9
787	S:S:L208	S:S:N211	33.7565	4.12	Yes	Yes	20	9	9
788	S:S:I189	S:S:L184	33.7571	2.85	No	Yes	0	9	9
789	S:S:C220	S:S:S217	84.4575	1.72	Yes	No	0	5	6
790	S:S:D194	S:S:S217	76.0118	8.83	No	No	0	8	6
791	S:S:D194	S:S:F195	33.783	3.58	No	Yes	46	8	2
792	S:S:D194	S:S:H219	33.783	2.52	No	Yes	46	8	5
793	S:S:D222	S:S:F195	16.8915	5.97	No	Yes	46	4	2
794	S:S:D222	S:S:H219	16.8915	16.39	No	Yes	46	4	5
795	S:S:A196	S:S:F197	33.7843	2.77	No	Yes	0	9	9
796	S:S:N210	S:S:Y234	22.5332	11.63	Yes	Yes	0	9	6
797	S:S:L208	S:S:L232	16.8866	4.15	Yes	No	0	9	9
798	S:S:L216	S:S:P241	16.9454	4.93	Yes	No	0	6	9
799	S:S:L247	S:S:L250	100	2.77	Yes	Yes	0	9	9
800	S:S:L250	S:S:L253	100	2.77	Yes	Yes	0	9	9
801	S:S:F255	S:S:L253	100	7.31	Yes	Yes	0	9	9
802	S:S:F255	S:S:N258	50.7364	3.62	Yes	Yes	15	9	9
803	S:S:H256	S:S:Y234	15.4702	4.36	Yes	Yes	47	9	6
804	S:S:F240	S:S:F255	33.7942	7.5	Yes	Yes	0	9	9
805	S:S:F268	S:S:L253	43.1337	3.65	Yes	Yes	0	9	9
806	S:S:F240	S:S:F268	100	4.29	Yes	Yes	0	9	9
807	S:S:L250	S:S:N271	100	4.12	Yes	Yes	15	9	9
808	S:S:F268	S:S:N271	42.2288	3.62	Yes	Yes	15	9	9
809	S:S:L250	S:S:L274	100	2.77	Yes	Yes	15	9	9
810	S:S:F268	S:S:L274	42.4692	3.65	Yes	Yes	15	9	9
811	S:S:F240	S:S:P264	67.5225	5.78	Yes	No	0	9	9
812	S:S:A267	S:S:F240	33.7613	2.77	No	Yes	0	9	9
813	S:S:H256	S:S:H278	11.253	3.58	Yes	No	0	9	8
814	S:S:K251	S:S:R275	50.6566	6.19	Yes	Yes	0	9	5
815	S:S:F255	S:S:I260	42.2076	5.02	Yes	No	15	9	9
816	S:S:I277	S:S:L274	100	2.85	Yes	Yes	15	8	9
817	S:S:N258	S:S:N282	33.7726	2.72	Yes	Yes	15	9	9
818	S:S:I260	S:S:N282	33.7655	7.08	No	Yes	15	9	9
819	S:S:N282	S:S:P283	33.7691	1.63	Yes	No	0	9	9
820	S:S:P283	S:S:S259	16.8846	3.56	No	No	0	9	6
821	S:S:F292	S:S:I277	100	2.51	Yes	Yes	0	9	8
822	S:S:F292	S:S:V287	100	2.62	Yes	Yes	0	9	9
823	S:S:G288	S:S:V287	59.1216	3.68	No	Yes	0	9	9
824	S:S:F286	S:S:G288	50.6757	6.02	No	No	0	4	9
825	S:S:F286	S:S:V262	16.892	2.62	No	No	0	4	5
826	S:S:I263	S:S:P264	33.7613	3.39	No	No	0	9	9
827	S:S:G270	S:S:N271	92.9169	1.7	No	Yes	0	6	9
828	S:S:D269	S:S:G270	84.47	1.68	No	No	0	3	6
829	S:S:D269	S:S:G266	76.023	5.03	No	No	0	3	4
830	S:S:D265	S:S:G266	67.5761	3.35	No	No	0	8	4
831	S:S:D265	S:S:S290	59.1291	7.36	No	No	0	8	8
832	S:S:L274	S:S:L295	100	4.15	Yes	No	0	9	9
833	S:S:D297	S:S:R275	19.6934	15.48	No	Yes	0	5	5
834	S:S:L284	S:S:N282	16.8846	2.75	No	Yes	0	8	9
835	S:S:F286	S:S:M308	25.3379	2.49	No	No	0	4	4
836	S:S:F292	S:S:L301	100	7.31	Yes	No	0	9	9
837	S:S:V287	S:S:V309	100	3.21	Yes	Yes	0	9	7
838	S:S:N289	S:S:S290	16.894	5.96	No	No	74	4	8
839	S:S:N314	S:S:S290	33.7881	5.96	No	No	74	7	8
840	S:S:N314	S:S:T316	25.3411	10.24	No	No	0	7	5
841	S:S:H293	S:S:T316	16.8941	2.74	No	No	0	7	5
842	S:S:L295	S:S:L298	100	5.54	No	No	0	9	9
843	S:S:L295	S:S:T318	100	2.95	No	No	0	9	8
844	S:S:L298	S:S:L321	100	2.77	No	No	0	9	8
845	S:S:L321	S:S:T318	100	4.42	No	No	0	8	8
846	S:S:H299	S:S:R275	29.5401	2.26	No	Yes	0	7	5
847	S:S:H299	S:S:H320	19.6934	3.58	No	No	0	7	7
848	S:S:E368	S:S:R392	18.5048	6.98	No	Yes	0	7	6
849	S:S:E368	S:S:R346	13.8787	6.98	No	No	0	7	7
850	S:S:L301	S:S:L324	100	4.15	No	No	0	9	9
851	S:S:T329	S:S:V309	100	4.76	Yes	Yes	34	8	7
852	S:S:G328	S:S:T329	100	3.64	No	Yes	0	7	8
853	S:S:G328	S:S:T327	100	3.64	No	Yes	0	7	9
854	S:S:R304	S:S:T327	16.8879	14.23	No	Yes	48	8	9
855	S:S:T325	S:S:T327	33.7755	3.14	Yes	Yes	48	8	9
856	S:S:I331	S:S:V309	100	3.07	Yes	Yes	34	8	7
857	S:S:L321	S:S:Q342	100	9.32	No	Yes	0	8	8
858	S:S:L345	S:S:Q342	100	5.32	No	Yes	0	9	8
859	S:S:L345	S:S:L367	100	5.54	No	No	0	9	7
860	S:S:I370	S:S:L367	100	5.71	Yes	No	0	7	7
861	S:S:I370	S:S:L394	100	2.85	Yes	Yes	0	7	7
862	S:S:F385	S:S:L394	100	9.74	No	Yes	0	9	7
863	S:S:F385	S:S:T384	100	6.49	No	No	0	9	8
864	S:S:K381	S:S:T384	100	3	No	No	0	1	8
865	S:S:K381	S:S:Q379	100	8.14	No	No	0	1	5
866	S:S:Q379	S:S:Y378	100	11.27	No	No	0	5	1
867	S:S:R356	S:S:Y378	100	10.29	No	No	0	3	1
868	S:S:Q376	S:S:R356	84.5064	1.17	No	No	0	4	3
869	S:S:N354	S:S:Q376	67.6052	7.92	No	No	0	3	4
870	S:S:K330	S:S:N354	33.8026	2.8	No	No	0	5	3
871	S:S:K330	S:S:Q310	16.9013	4.07	No	No	0	5	5
872	S:S:F312	S:S:I331	33.7742	2.51	No	Yes	0	8	8
873	S:S:L324	S:S:L326	76.4281	5.54	No	Yes	0	9	7
874	S:S:F312	S:S:P335	25.3303	11.56	No	No	0	8	8
875	S:S:L315	S:S:Q342	16.8856	2.66	No	Yes	0	9	8
876	S:S:L324	S:S:L348	76.4273	4.15	No	No	0	9	9
877	S:S:D349	S:S:T325	16.8883	7.23	No	Yes	0	8	8
878	S:S:S351	S:S:T327	100	4.8	Yes	Yes	0	9	9
879	S:S:D349	S:S:S351	16.8882	2.94	No	Yes	0	8	9
880	S:S:L326	S:S:L350	59.5559	2.77	Yes	Yes	0	7	9
881	S:S:L348	S:S:L350	59.5457	4.15	No	Yes	0	9	9
882	S:S:N353	S:S:T329	100	8.77	Yes	Yes	34	9	8
883	S:S:I331	S:S:N353	100	8.5	Yes	Yes	34	8	9
884	S:S:I334	S:S:L350	50.6692	4.28	No	Yes	0	7	9
885	S:S:I334	S:S:P359	33.7827	6.77	No	Yes	0	7	9
886	S:S:N337	S:S:P335	16.889	6.52	No	No	0	3	8
887	S:S:L367	S:S:L388	100	6.92	No	No	0	7	8
888	S:S:G387	S:S:L388	100	1.71	No	No	0	5	8
889	S:S:G387	S:S:H365	100	3.18	No	No	0	5	3
890	S:S:G363	S:S:H365	50.6602	3.18	No	No	0	4	3
891	S:S:C339	S:S:G363	16.8867	1.96	No	No	75	9	4
892	S:S:C364	S:S:G363	16.8867	1.96	No	No	75	9	4
893	S:S:E341	S:S:Q342	33.7712	3.82	No	Yes	0	5	8
894	S:S:D349	S:S:S371	16.8881	4.42	No	No	0	8	6
895	S:S:Q373	S:S:S351	100	2.89	Yes	Yes	0	8	9
896	S:S:L350	S:S:L372	51.616	2.77	Yes	Yes	0	9	8
897	S:S:S351	S:S:Y352	42.2192	8.9	Yes	No	0	9	7
898	S:S:R374	S:S:Y352	33.7756	23.66	No	No	0	8	7
899	S:S:Q373	S:S:R374	33.7756	8.18	Yes	No	0	8	8
900	S:S:I355	S:S:N353	100	4.25	No	Yes	34	8	9
901	S:S:N353	S:S:N375	16.8863	2.72	Yes	No	34	9	9
902	S:S:I355	S:S:I377	100	2.94	No	No	0	8	7
903	S:S:D357	S:S:R356	16.9013	3.57	No	No	0	3	3
904	S:S:L358	S:S:L372	16.8889	4.15	No	Yes	0	8	8
905	S:S:F361	S:S:I370	16.8963	2.51	No	Yes	0	6	7
906	S:S:I377	S:S:N399	100	9.91	No	No	0	7	9
907	S:S:I401	S:S:N399	100	2.83	Yes	No	16	8	9
908	S:S:I401	S:S:I404	100	2.94	Yes	No	16	8	7
909	S:S:I404	S:S:P429	100	6.77	No	No	0	7	9
910	S:S:P429	S:S:S406	100	1.78	No	Yes	0	9	3
911	S:S:H405	S:S:S406	100	2.79	No	Yes	40	6	3
912	S:S:E382	S:S:H405	100	12.31	No	No	0	4	6
913	S:S:E382	S:S:G383	100	4.91	No	No	0	4	4
914	S:S:G383	S:S:Q386	100	1.64	No	No	0	4	4
915	S:S:N362	S:S:Q386	67.5255	2.64	No	No	0	4	4
916	S:S:L394	S:S:L418	100	4.15	Yes	Yes	0	7	9
917	S:S:L418	S:S:L439	100	2.77	Yes	Yes	0	9	8
918	S:S:F428	S:S:L439	100	7.31	Yes	Yes	16	4	8
919	S:S:F428	S:S:P429	100	2.89	Yes	No	0	4	9
920	S:S:N362	S:S:S360	33.7627	4.47	No	No	0	4	7
921	S:S:H365	S:S:I389	50.6574	14.58	No	No	0	3	3
922	S:S:I370	S:S:L391	16.9004	5.71	Yes	No	0	7	9
923	S:S:L388	S:S:L391	16.8916	5.54	No	No	0	8	9
924	S:S:L372	S:S:L396	17.3465	4.15	Yes	No	0	8	9
925	S:S:D395	S:S:Q373	100	5.22	No	Yes	76	9	8
926	S:S:Q373	S:S:S397	33.7754	5.78	Yes	No	76	8	8
927	S:S:R374	S:S:R398	50.6634	8.53	No	No	0	8	5
928	S:S:R398	S:S:S397	25.3316	2.64	No	No	0	5	8
929	S:S:E403	S:S:Q379	33.8026	8.92	No	No	0	2	5
930	S:S:I380	S:S:T384	16.9013	3.04	No	No	0	7	8
931	S:S:G387	S:S:T411	16.8868	5.46	No	No	0	5	4
932	S:S:D395	S:S:D419	100	5.32	No	No	0	9	9
933	S:S:F422	S:S:R398	50.6637	11.76	No	No	0	4	5
934	S:S:N399	S:S:N423	16.8946	6.81	No	No	16	9	9
935	S:S:I401	S:S:L425	33.7804	2.85	Yes	Yes	16	8	9
936	S:S:L418	S:S:V420	50.6562	2.98	Yes	No	0	9	6
937	S:S:L425	S:S:V420	33.7546	2.98	Yes	No	0	9	6
938	S:S:E403	S:S:H402	16.9013	11.08	No	No	0	2	3
939	S:S:R407	S:S:S406	100	2.64	Yes	Yes	40	4	3
940	S:S:E431	S:S:S406	100	2.87	No	Yes	40	3	3
941	S:S:A410	S:S:R407	100	2.77	No	Yes	40	3	4
942	S:S:A410	S:S:E431	100	4.53	No	No	40	3	3
943	S:S:F409	S:S:L418	50.7034	6.09	No	Yes	0	8	9
944	S:S:A408	S:S:F409	16.9013	2.77	No	No	0	8	8
945	S:S:F409	S:S:L433	16.9009	10.96	No	No	0	8	9
946	S:S:I415	S:S:L418	50.7096	4.28	No	Yes	0	7	9
947	S:S:I415	S:S:L412	16.91	8.56	No	No	0	7	8
948	S:S:G413	S:S:I389	33.7724	1.76	No	No	0	3	3
949	S:S:G413	S:S:P414	16.887	4.06	No	No	0	3	5
950	S:S:I415	S:S:L436	16.9036	5.71	No	No	0	7	8
951	S:S:L436	S:S:L439	16.9041	2.77	No	Yes	0	8	8
952	S:S:D419	S:S:S421	16.8878	5.89	No	No	0	9	7
953	S:S:D419	S:S:K440	100	16.59	No	No	0	9	8
954	S:S:F422	S:S:G443	25.3319	4.52	No	No	0	4	8
955	S:S:L439	S:S:L462	100	4.15	Yes	Yes	0	8	7
956	S:S:L462	S:S:V464	100	4.47	Yes	No	0	7	7
957	S:S:P465	S:S:V464	100	3.53	No	No	78	9	7
958	S:S:P465	S:S:Y466	100	4.17	No	No	0	9	6
959	S:S:K448	S:S:Y466	100	7.17	No	No	0	7	6
960	S:S:E449	S:S:K448	100	1.35	No	No	0	4	7
961	S:S:E449	S:S:S427	84.5066	2.87	No	No	0	4	4
962	S:S:S427	S:S:T426	67.6053	1.6	No	No	0	4	4
963	S:S:K446	S:S:T426	50.704	4.5	No	No	0	3	4
964	S:S:E424	S:S:K446	33.8027	8.1	No	No	0	3	3
965	S:S:E424	S:S:F445	16.9013	8.16	No	No	0	3	1
966	S:S:L425	S:S:N444	33.7715	5.49	Yes	No	16	9	9
967	S:S:L439	S:S:L441	50.6783	6.92	Yes	Yes	16	8	8
968	S:S:L441	S:S:N444	16.8779	2.75	Yes	No	16	8	9
969	S:S:F428	S:S:T430	84.5085	2.59	Yes	No	0	4	5
970	S:S:F428	S:S:L451	33.8034	3.65	Yes	No	0	4	7
971	S:S:D455	S:S:T430	50.7054	8.67	No	No	0	4	5
972	S:S:F456	S:S:T430	16.9022	5.19	No	No	0	5	5
973	S:S:F456	S:S:L451	16.9018	3.65	No	No	0	5	7
974	S:S:L459	S:S:L462	33.8028	5.54	No	Yes	0	7	7
975	S:S:F456	S:S:L459	16.9019	6.09	No	No	0	5	7
976	S:S:A410	S:S:G432	100	1.95	No	No	0	3	8
977	S:S:G432	S:S:N434	100	1.7	No	No	0	8	3
978	S:S:N434	S:S:V457	67.5254	7.39	No	No	0	3	4
979	S:S:K440	S:S:S463	100	9.18	No	No	0	8	8
980	S:S:L441	S:S:L447	16.9002	2.77	Yes	No	16	8	7
981	S:S:K448	S:S:T614	16.9013	4.5	No	No	0	7	4
982	S:S:Q469	S:S:V464	33.8026	5.73	No	No	78	9	7
983	S:S:A450	S:S:Q469	16.9013	3.03	No	No	0	4	9
984	S:S:A452	S:S:D455	16.9018	6.18	No	No	77	3	4
985	S:S:D455	S:S:K454	16.9018	6.91	No	No	77	4	5
986	S:S:F473	S:S:L462	50.704	3.65	No	Yes	0	8	7
987	S:S:A453	S:S:F473	16.9013	4.16	No	No	0	4	8
988	S:S:S463	S:S:T523	100	7.99	No	No	0	8	6
989	S:S:F789	S:S:V763	94.7197	1.31	Yes	No	0	7	9
990	S:S:F760	S:S:V763	54.2748	1.31	Yes	No	0	8	9
991	S:S:F760	S:S:N714	47.5628	6.04	Yes	Yes	0	8	9
992	S:S:L710	S:S:N714	38.5362	2.75	No	Yes	0	9	9
993	S:S:F706	S:S:L710	38.1514	2.44	Yes	No	0	5	9
994	S:S:F706	S:S:P695	30.4535	5.78	Yes	No	0	5	9
995	S:S:F696	S:S:P695	30.0685	4.33	No	No	0	7	9
996	S:S:F696	S:S:P697	16.191	11.56	No	Yes	49	7	7
997	S:S:P524	S:S:T523	100	5.25	No	No	0	9	6
998	S:S:C522	S:S:P524	100	1.88	No	No	0	9	9
999	S:S:C470	S:S:C522	92.8837	7.28	No	No	0	9	9
1000	S:S:C470	S:S:T526	75.9959	5.07	No	No	0	9	8
1001	S:S:C471	S:S:T526	59.108	5.07	No	No	0	9	8
1002	S:S:C471	S:S:C532	42.22	7.28	No	No	35	9	9
1003	S:S:F473	S:S:I520	16.9013	3.77	No	No	0	8	5
1004	S:S:C532	S:S:E533	33.7761	3.04	No	No	35	9	4
1005	S:S:E533	S:S:Y534	16.888	7.86	No	No	35	4	4
1006	S:S:F696	S:S:L694	13.4925	6.09	No	Yes	49	7	7
1007	S:S:L692	S:S:L787	14.6507	2.77	No	No	0	7	9
1008	S:S:L536	S:S:L787	13.8798	4.15	Yes	No	0	5	9
1009	S:S:F790	S:S:V763	40.3531	1.31	Yes	No	0	5	9
1010	S:S:F790	S:S:M587	28.9007	6.22	Yes	No	0	5	6
1011	S:S:A794	S:S:M587	22.4694	4.83	No	No	0	8	6
1012	S:S:A794	S:S:N584	22.0928	4.69	No	Yes	0	8	9
1013	S:S:N556	S:S:N584	12.9589	6.81	Yes	Yes	36	9	9
1014	S:S:N556	S:S:S581	14.1341	2.98	Yes	No	0	9	7
1015	S:S:S581	S:S:V559	11.9469	8.08	No	No	0	7	8
1016	S:S:N584	S:S:N797	10.8969	6.81	Yes	Yes	36	9	9
1017	S:S:L752	S:S:N797	12.2049	4.12	No	Yes	0	9	9
1018	S:S:H748	S:S:L752	11.7359	14.14	No	No	0	9	9
1019	S:S:W751	X:X:?1	66.8996	12.49	Yes	Yes	5	8	0
1020	S:S:W751	T:T:L236	61.174	5.69	Yes	Yes	5	8	9
1021	T:T:K239	T:T:L236	56.4865	2.82	Yes	Yes	5	9	9
1022	S:S:Y729	T:T:K239	45.0105	13.14	No	Yes	0	9	9
1023	S:S:Y725	S:S:Y729	41.1853	8.94	Yes	No	0	8	9
1024	S:S:I746	S:S:Y725	35.4476	3.63	No	Yes	0	7	8
1025	S:S:I746	S:S:R643	31.6236	5.01	No	Yes	0	7	8
1026	S:S:E642	S:S:R643	24.8934	8.14	Yes	Yes	26	8	8
1027	S:S:E642	S:S:F662	11.4895	5.83	Yes	No	26	8	4
1028	S:S:A673	S:S:E630	11.3734	3.02	No	Yes	83	8	8
1029	S:S:A673	S:S:F627	10.6234	2.77	No	Yes	0	8	5
1030	S:S:F627	S:S:T674	10.1981	7.78	Yes	No	0	5	3
1031	S:S:F804	X:X:?1	20.2418	31.58	No	Yes	5	9	0
1032	S:S:L796	S:S:N797	15.993	5.49	No	Yes	0	8	9
1033	S:S:F804	S:S:L800	18.3539	6.09	No	No	0	9	9
1034	T:T:I205	T:T:V61	11.4766	3.07	No	No	0	9	9
1035	T:T:P179	T:T:R178	10.4244	5.76	Yes	Yes	0	9	9
1036	T:T:E62	T:T:R204	25.1322	12.79	No	Yes	0	9	9
1037	T:T:K197	T:T:N196	17.2581	12.59	No	No	0	9	9
1038	T:T:K197	T:T:Q198	14.3818	4.07	No	No	0	9	9
1039	T:T:R149	T:T:W120	18.7492	2	No	Yes	0	9	9
1040	T:T:R145	T:T:R149	15.2339	11.73	Yes	No	0	9	9
1041	T:T:E130	T:T:Q128	100	7.65	No	Yes	0	6	9
1042	T:T:E130	T:T:P129	100	6.29	No	No	0	6	9
1043	T:T:N161	T:T:P129	100	6.52	No	No	0	9	9
1044	T:T:A164	T:T:N161	100	3.13	No	No	0	9	9
1045	L:L:C96	L:L:G81	18.2744	1.96	No	No	0	0	0
1046	L:L:A130	L:L:G131	100	1.95	No	No	0	0	0
1047	R:R:A243	R:R:C220	83.7543	1.81	No	Yes	0	8	5
1048	R:R:N282	R:R:P283	83.7919	1.63	Yes	No	0	9	9
1049	R:R:P283	R:R:S259	55.8613	1.78	No	No	0	9	6
1050	R:R:P177	R:R:T178	27.9197	1.75	No	No	0	4	5
1051	R:R:G270	R:R:N271	83.7646	1.7	No	Yes	0	6	9
1052	R:R:G270	R:R:K245	27.9215	1.74	No	No	0	6	5
1053	R:R:G238	R:R:L237	13.9696	1.71	No	Yes	0	2	8
1054	S:S:C35	S:S:V41	16.8844	1.71	No	No	0	9	7
1055	R:R:G47	R:R:N67	100	1.7	No	Yes	0	7	9
1056	R:R:G47	R:R:N68	100	1.7	No	No	0	7	9
1057	R:R:A196	R:R:V170	100	1.7	No	No	0	9	6
1058	R:R:G254	R:R:N233	27.4123	1.7	No	Yes	0	7	9
1059	R:R:A306	R:R:V287	27.9275	1.7	No	No	0	9	9
1060	R:R:G317	R:R:N294	27.9215	1.7	No	No	0	7	6
1061	R:R:A306	R:R:V309	13.9637	1.7	No	No	0	9	7
1062	R:R:N434	R:R:V457	13.7548	1.48	No	No	0	3	4
1063	S:S:G47	S:S:N67	100	1.7	No	Yes	0	7	9
1064	S:S:A196	S:S:V170	16.8921	1.7	No	No	0	9	6
1065	R:R:D36	R:R:R40	100	1.19	No	Yes	0	5	3
1066	R:R:D36	R:R:G37	54.8212	1.68	No	No	0	5	4
1067	R:R:D269	R:R:G270	27.9215	1.68	No	No	0	3	6
1068	S:S:N336	S:S:P359	16.8863	1.63	No	Yes	0	1	9
1069	E:E:I189	E:E:N193	18.3222	1.42	No	No	0	5	9
1070	E:E:K197	E:E:N193	27.4833	1.4	No	No	0	9	9
1071	S:S:A100	S:S:I96	16.8844	1.62	No	Yes	0	8	9
1072	R:R:Q71	R:R:T70	55.8397	1.42	No	No	0	4	8
1073	R:R:S94	R:R:T70	27.9199	1.6	No	No	0	5	8
1074	R:R:A78	R:R:D75	55.8397	1.54	No	Yes	0	4	4
1075	S:S:A246	S:S:D222	16.8915	1.54	No	No	0	5	4
1076	L:L:K114	L:L:V115	18.2743	1.52	Yes	No	0	0	0
1077	R:R:K343	R:R:V319	10.4725	1.52	No	No	0	7	4
1078	R:R:N236	R:R:S259	27.9306	1.49	No	No	0	5	6
1079	S:S:N354	S:S:S332	16.9013	1.49	No	No	0	3	4
1080	R:R:N68	R:R:T49	100	1.46	No	No	0	9	4
1081	M:M:D136	M:M:T138	16.8857	1.45	No	No	0	0	0
1082	R:R:Q180	R:R:S202	100	1.44	Yes	No	0	9	8
1083	S:S:A57	S:S:F82	16.8844	1.39	No	No	0	4	5
1084	S:S:E341	S:S:K343	16.8856	1.35	No	No	0	5	7
1085	R:R:F58	R:R:S56	54.8212	1.32	No	No	0	6	6
1086	L:L:R86	R:R:A138	100	4.15	Yes	No	1	0	9
1087	R:R:D137	R:R:D161	100	7.98	Yes	Yes	1	9	9
1088	R:R:R135	R:R:W159	100	17.99	Yes	Yes	1	9	9
1089	R:R:H209	R:R:N210	36.5606	7.65	Yes	Yes	1	9	9
1090	L:L:L59	L:L:Q56	100	5.32	No	No	0	0	0
1091	L:L:C55	L:L:C74	100	7.28	Yes	Yes	3	0	0
1092	E:E:H102	L:L:Q70	100	3.71	Yes	No	3	9	0
1093	E:E:R149	E:E:Y116	54.8107	3.09	No	Yes	0	9	9
1094	T:T:L131	T:T:Q128	100	3.99	Yes	Yes	4	9	9
1095	M:M:L44	M:M:R54	100	7.29	No	No	0	0	0
1096	M:M:N50	T:T:P103	15.0473	6.52	Yes	No	4	0	9
1097	E:E:P210	E:E:Q212	14.7257	7.9	Yes	No	0	9	8
1098	T:T:G119	T:T:Y118	74.1759	2.9	Yes	Yes	7	9	9
1099	E:E:R145	E:E:R149	18.271	4.26	Yes	No	54	9	9
1100	T:T:E95	T:T:R204	100	19.77	Yes	Yes	0	8	9
1101	T:T:R204	T:T:V64	27.4024	6.54	Yes	Yes	29	9	9
1102	E:E:R178	E:E:T152	100	6.47	Yes	No	0	9	9
1103	T:T:E62	T:T:T78	22.8349	2.82	No	Yes	0	9	9
1104	E:E:M219	T:T:F222	18.4894	4.98	No	Yes	9	9	9
1105	S:S:L796	S:S:L800	16.4496	2.77	No	No	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:S45	T:T:L131	7.51	4	No	Yes	0	9	0	1
M:M:S47	T:T:E127	8.62	4	No	Yes	0	9	0	1
M:M:D49	T:T:K125	9.68	4	No	Yes	0	9	0	1
M:M:D49	T:T:M192	6.93	4	No	Yes	0	9	0	1
M:M:N50	T:T:Q100	3.96	4	Yes	No	0	7	0	1
M:M:N50	T:T:H102	10.2	4	Yes	Yes	0	9	0	1
M:M:N50	T:T:P103	6.52	4	Yes	No	0	9	0	1
M:M:N50	T:T:K125	6.99	4	Yes	Yes	0	9	0	1
M:M:N50	T:T:E127	6.57	4	Yes	Yes	0	9	0	1
M:M:S53	T:T:H102	5.58	4	No	Yes	0	9	0	1
M:M:S53	T:T:L104	3	4	No	Yes	0	9	0	1
M:M:R54	T:T:L131	7.29	4	No	Yes	0	9	0	1
M:M:K58	S:S:N114	2.8	6	Yes	Yes	0	9	0	1
M:M:K58	S:S:A138	3.21	6	Yes	No	0	9	0	1
M:M:K58	S:S:H140	2.62	6	Yes	No	0	8	0	1
M:M:K58	S:S:D162	15.21	6	Yes	No	0	9	0	1
M:M:F61	T:T:L104	6.09	4	Yes	Yes	0	9	0	1
M:M:L63	T:T:H102	5.14	0	Yes	Yes	0	9	0	1
M:M:R65	T:T:V99	3.92	7	No	Yes	0	7	0	1
M:M:R65	T:T:Y116	10.29	7	No	Yes	0	9	0	1
M:M:M68	T:T:I98	2.92	53	No	No	0	8	0	1
M:M:M68	T:T:V195	4.56	53	No	No	0	9	0	1
M:M:M68	T:T:A201	3.22	53	No	No	0	9	0	1
M:M:R69	T:T:N196	3.62	12	No	No	0	9	0	1
M:M:H76	S:S:G90	3.18	0	No	No	0	9	0	1
M:M:H76	S:S:Q113	3.71	0	No	Yes	0	9	0	1
M:M:S77	S:S:Q113	4.33	0	No	Yes	0	9	0	1
M:M:H85	S:S:H209	3.58	0	No	Yes	0	9	0	1
M:M:R86	S:S:Q113	3.5	6	Yes	Yes	0	9	0	1
M:M:R86	S:S:D137	5.96	6	Yes	Yes	0	9	0	1
M:M:R86	S:S:A138	2.77	6	Yes	No	0	9	0	1
M:M:R86	S:S:D161	10.72	6	Yes	No	0	9	0	1
M:M:R86	S:S:D162	3.57	6	Yes	No	0	9	0	1
M:M:R86	S:S:L186	3.64	6	Yes	Yes	0	9	0	1
M:M:P88	S:S:N210	9.77	0	No	Yes	0	9	0	1
M:M:D89	T:T:K134	6.91	0	No	No	0	9	0	1
M:M:M90	T:T:L104	2.83	4	No	Yes	0	9	0	1
M:M:R97	T:T:E112	6.98	0	No	No	0	9	0	1
M:M:F105	S:S:W159	13.03	6	Yes	Yes	0	9	0	1
M:M:F105	S:S:A181	8.32	6	Yes	No	0	9	0	1
M:M:F105	S:S:T183	5.19	6	Yes	No	0	9	0	1
M:M:F105	S:S:V205	2.62	6	Yes	Yes	0	9	0	1
M:M:S106	S:S:V205	3.23	6	No	Yes	0	9	0	1
M:M:S106	S:S:H207	4.18	6	No	Yes	0	9	0	1
M:M:K107	T:T:D111	4.15	0	No	No	0	9	0	1
M:M:D108	S:S:T229	5.78	0	No	No	0	9	0	1
M:M:D108	S:S:E252	5.2	0	No	No	0	9	0	1
M:M:F109	S:S:H157	4.53	6	Yes	Yes	0	9	0	1
M:M:F109	S:S:Q180	3.51	6	Yes	No	0	9	0	1
M:M:F109	S:S:A181	2.77	6	Yes	No	0	9	0	1
M:M:F109	S:S:V204	6.55	6	Yes	Yes	0	9	0	1
M:M:F109	S:S:V205	6.55	6	Yes	Yes	0	9	0	1
M:M:T111	S:S:H157	10.95	0	No	Yes	0	9	0	1
M:M:R121	S:S:V204	3.92	0	No	Yes	0	9	0	1
M:M:R121	S:S:N226	10.85	0	No	No	0	8	0	1
M:M:R123	S:S:K251	4.95	0	No	Yes	0	9	0	1
S:S:A89	S:S:Q113	6.06	0	No	Yes	9	9	2	1
S:S:G90	S:S:N114	3.39	0	No	Yes	9	9	1	1
S:S:N114	S:S:Q113	2.64	6	Yes	Yes	9	9	1	1
S:S:Q113	S:S:R135	5.84	6	Yes	Yes	9	9	1	2
S:S:D137	S:S:Q113	10.44	6	Yes	Yes	9	9	1	1
S:S:A138	S:S:N114	4.69	6	No	Yes	9	9	1	1
S:S:H140	S:S:K118	5.24	0	No	No	8	4	1	2
S:S:H157	S:S:S133	6.97	6	Yes	No	9	9	1	2
S:S:D137	S:S:R135	16.68	6	Yes	Yes	9	9	1	2
S:S:R135	S:S:W159	13	6	Yes	Yes	9	9	2	1
S:S:D137	S:S:W159	3.35	6	Yes	Yes	9	9	1	1
S:S:D137	S:S:D161	11.98	6	Yes	No	9	9	1	1
S:S:H157	S:S:R156	10.16	6	Yes	No	9	9	1	2
S:S:Q180	S:S:R156	11.68	0	No	No	9	9	1	2
S:S:H157	S:S:W159	5.29	6	Yes	Yes	9	9	1	1
S:S:A181	S:S:H157	2.93	6	No	Yes	9	9	1	1
S:S:D161	S:S:W159	3.35	6	No	Yes	9	9	1	1
S:S:D162	S:S:L186	6.79	6	No	Yes	9	9	1	1
S:S:Q180	S:S:S202	2.89	0	No	No	9	8	1	2
S:S:H207	S:S:T183	9.58	6	Yes	No	9	9	1	1
S:S:A185	S:S:L186	3.15	0	No	Yes	9	9	2	1
S:S:A185	S:S:H209	4.39	0	No	Yes	9	9	2	1
S:S:L186	S:S:N210	4.12	6	Yes	Yes	9	9	1	1
S:S:V204	S:S:V205	3.21	6	Yes	Yes	9	9	1	1
S:S:E228	S:S:V204	5.7	0	No	Yes	9	9	2	1
S:S:H207	S:S:V205	4.15	6	Yes	Yes	9	9	1	1
S:S:T229	S:S:V205	9.52	0	No	Yes	9	9	1	1
S:S:D231	S:S:H207	11.35	0	No	Yes	9	9	2	1
S:S:H209	S:S:N210	3.83	0	Yes	Yes	9	9	1	1
S:S:H209	S:S:N233	5.1	0	Yes	Yes	9	9	1	2
S:S:N210	S:S:Y234	11.63	0	Yes	Yes	9	6	1	2
S:S:D225	S:S:N226	2.69	0	No	No	4	8	2	1
S:S:E228	S:S:K251	5.4	0	No	Yes	9	9	2	1
S:S:D231	S:S:T229	2.89	0	No	No	9	9	2	1
S:S:D231	S:S:N233	4.04	0	No	Yes	9	9	2	2
S:S:N233	S:S:Y234	3.49	47	Yes	Yes	9	6	2	2
S:S:E252	S:S:K251	2.7	0	No	Yes	9	9	1	1
S:S:K251	S:S:R275	6.19	0	Yes	Yes	9	5	1	2
T:T:A201	T:T:I98	4.87	53	No	No	9	8	1	1
T:T:A203	T:T:I98	3.25	0	No	No	9	8	2	1
T:T:M101	T:T:V99	3.04	7	Yes	Yes	9	7	2	1
T:T:V99	T:T:Y116	2.52	7	Yes	Yes	7	9	1	1
T:T:V99	T:T:W120	12.26	7	Yes	Yes	7	9	1	2
T:T:Q100	T:T:V195	2.87	0	No	No	7	9	1	1
T:T:M101	T:T:Y116	5.99	7	Yes	Yes	9	9	2	1
T:T:M101	T:T:W120	6.98	7	Yes	Yes	9	9	2	2
T:T:H102	T:T:P103	10.68	4	Yes	No	9	9	1	1
T:T:H102	T:T:L104	7.71	4	Yes	Yes	9	9	1	1
T:T:P103	T:T:V124	3.53	4	No	No	9	9	1	2
T:T:D114	T:T:Y116	4.6	0	No	Yes	9	9	2	1
T:T:W120	T:T:Y116	2.89	7	Yes	Yes	9	9	2	1
T:T:M192	T:T:V123	3.04	4	Yes	No	9	9	1	2
T:T:D157	T:T:K125	8.3	4	Yes	Yes	9	9	2	1
T:T:K125	T:T:M192	4.32	4	Yes	Yes	9	9	1	1
T:T:E127	T:T:Q128	5.1	4	Yes	Yes	9	9	1	2
T:T:E127	T:T:L131	2.65	4	Yes	Yes	9	9	1	1
T:T:L131	T:T:Q128	3.99	4	Yes	Yes	9	9	1	2
T:T:D132	T:T:L131	4.07	0	No	Yes	9	9	2	1
T:T:D132	T:T:P135	3.22	0	No	No	9	9	2	2
T:T:D157	T:T:M192	6.93	4	Yes	Yes	9	9	2	1
T:T:K197	T:T:N196	12.59	0	No	No	9	9	2	1
S:S:H140	S:S:Q116	2.47	0	No	No	8	6	1	2
M:M:L63	T:T:G105	1.71	0	Yes	No	0	9	0	1
T:T:K134	T:T:P133	1.67	0	No	No	9	9	1	2
T:T:K134	T:T:P135	1.67	0	No	No	9	9	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
85.71	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3
80.00	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
71.43	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-Cholesterol-ZNRF3
68.00	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3
5.26	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.26	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
5.26	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.26	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.26	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
5.26	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
5.26	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.26	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.26	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.26	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
5.26	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
5.26	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
5.26	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
5.26	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.26	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.26	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.26	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.26	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
5.26	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
5.26	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
5.26	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
5.26	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
5.26	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.26	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.26	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.26	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.26	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.26	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.26	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
5.26	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
5.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.26	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.26	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.26	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.26	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
5.26	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
5.26	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
5.26	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.26	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.26	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.26	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.26	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.26	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.26	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
5.26	Single	7XW7	K1-70	7XW7-TSH-K1-70
5.26	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.26	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.26	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.26	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.26	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.26	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.26	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.26	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.26	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.26	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.26	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.26	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.26	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
5.26	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.26	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.26	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.26	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.26	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
5.26	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
5.26	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.26	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.26	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
5.26	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
5.26	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.26	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
5.26	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
5.26	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
5.26	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.26	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.26	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.26	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.26	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.26	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.26	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
5.26	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
5.26	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
5.26	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
5.26	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
5.26	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
5.26	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
5.26	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
5.26	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
5.26	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
5.26	Single	8WG9	(2S)-2-amino-4-phosphonobutanoic acid	8WG9-mGlu4; mGlu2-(2S)-2-amino-4-phosphonobutanoic acid
5.26	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
5.26	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
5.26	Single	8WGC	LY379268	8WGC-mGlu4; mGlu2-LY379268
5.26	Single	8WGD	WAG/WA6	8WGD-mGlu4; mGlu2-WAG/WA6
5.26	Single	8WGD	WAG/WA6	8WGD-mGlu4; mGlu2-WAG/WA6
5.26	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.26	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.26	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8WVX	Norrin	8WVX-LGR4-Norrin
5.26	Single	8WVY	Norrin	8WVY-LGR4-Norrin
5.26	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
5.26	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
5.26	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
5.26	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
5.26	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
5.26	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
5.26	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
5.26	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
5.26	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.26	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.26	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.26	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.26	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.26	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.26	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.26	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.26	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.26	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.26	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.26	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.26	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.26	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.26	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.26	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.26	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
5.26	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
5.26	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
5.26	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
5.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
4.76	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
4.76	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
4.55	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
4.55	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
4.55	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
4.55	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
4.55	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
4.35	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
4.35	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
4.35	Single	8HS2	Fab046	8HS2-GPR20-Fab046
4.35	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
4.35	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
4.35	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
4.17	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
4.17	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/β1/γ2
4.17	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
4.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
4.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
4.00	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
4.00	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
4.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
4.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
3.85	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
3.85	Single	6LI0	C17	6LI0-GPR52-C17
3.85	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
3.85	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
3.85	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
3.85	Single	9B9Y	7DY	9B9Y-CB₁-7DY
3.70	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
3.70	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
3.70	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
3.70	Single	5U09	Taranabant	5U09-CB₁-Taranabant
3.70	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
3.70	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
3.70	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
3.70	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
3.70	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
3.70	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
3.70	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
3.70	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
3.70	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
3.70	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
3.70	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
3.70	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
3.70	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
3.70	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
3.70	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
3.70	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
3.70	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
3.70	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
3.70	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
3.57	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
3.57	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
3.57	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
3.57	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
3.57	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
3.57	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
3.57	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
3.57	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
3.57	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
3.57	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
3.57	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
3.57	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
3.45	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
3.45	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
3.45	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
3.45	Single	6D27	CAY10471	6D27-DP₂-CAY10471
3.45	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
3.45	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
3.45	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
3.45	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
3.45	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
3.45	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
3.45	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
3.45	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
3.45	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
3.45	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
3.45	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
3.45	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
3.45	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
3.45	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
3.45	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
3.45	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
3.45	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
3.45	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
3.45	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
3.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
3.33	Single	5C1M	BU72	5C1M-μ-BU72
3.33	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
3.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
3.33	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
3.33	Single	7C4S	S1P	7C4S-S1P₃-S1P
3.33	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
3.33	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
3.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
3.33	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
3.33	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
3.33	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.33	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.33	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
3.33	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
3.23	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
3.23	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
3.23	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
3.23	Single	5V56	TC114	5V56-SMO-TC114
3.23	Single	5V57	TC114	5V57-SMO-TC114
3.23	Single	6OS1	TRV026	6OS1-AT₁-TRV026
3.23	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
3.23	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
3.23	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
3.23	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
3.23	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
3.23	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
3.23	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
3.23	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
3.23	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
3.23	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
3.23	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
3.23	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
3.23	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
3.23	Single	8E0G	BU72	8E0G-μ-BU72
3.23	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.23	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
3.23	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
3.23	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
3.23	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
3.23	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
3.23	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
3.23	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
3.23	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
3.23	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
3.23	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
3.23	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.23	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
3.23	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
3.23	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
3.23	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.23	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
3.23	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
3.23	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
3.12	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
3.12	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
3.12	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
3.12	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
3.12	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
3.12	Single	6OS2	TRV026	6OS2-AT₁-TRV026
3.12	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
3.12	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
3.12	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
3.12	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
3.12	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
3.12	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.12	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
3.12	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
3.12	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
3.12	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
3.12	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
3.12	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.12	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
3.12	Single	8XQJ	JN241	8XQJ-Apelin-JN241
3.12	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
3.12	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
3.12	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
3.12	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
3.12	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
3.12	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
3.12	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
3.12	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
3.12	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
3.12	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.12	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
3.12	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
3.12	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
3.12	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
3.12	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
3.12	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
3.12	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
3.12	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
3.12	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
3.12	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.12	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
3.12	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
3.12	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
3.03	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
3.03	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
3.03	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
3.03	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.03	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
3.03	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
3.03	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
3.03	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
3.03	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
3.03	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
3.03	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
3.03	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
3.03	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
3.03	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
3.03	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
3.03	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
3.03	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
3.03	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
3.03	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
3.03	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
3.03	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
3.03	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
3.03	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
3.03	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
3.03	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
3.03	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
3.03	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
2.94	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
2.94	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
2.94	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
2.94	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
2.94	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
2.94	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
2.94	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
2.94	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
2.94	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
2.94	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
2.94	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
2.94	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
2.94	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
2.94	Single	8XQJ	JN241	8XQJ-Apelin-JN241
2.94	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
2.94	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
2.94	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
2.94	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
2.94	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
2.94	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
2.94	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
2.86	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
2.86	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
2.86	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
2.86	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
2.86	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
2.86	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
2.86	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
2.86	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
2.86	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
2.86	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
2.86	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
2.86	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
2.86	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
2.86	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
2.86	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
2.86	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
2.86	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
2.86	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
2.86	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
2.86	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
2.86	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
2.86	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
2.86	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
2.86	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
2.86	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
2.86	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
2.86	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
2.86	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
2.78	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
2.78	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
2.78	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
2.78	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
2.78	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
2.78	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
2.78	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
2.78	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
2.78	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
2.78	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
2.78	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
2.78	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
2.78	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
2.78	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
2.78	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
2.78	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
2.78	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
2.78	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
2.78	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
2.78	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
2.78	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
2.70	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
2.70	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
2.70	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
2.70	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
2.70	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
2.70	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
2.70	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
2.70	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
2.70	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
2.70	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
2.70	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
2.70	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
2.70	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
2.70	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
2.70	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
2.70	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
2.70	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.70	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.70	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
2.70	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
2.70	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
2.70	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
2.70	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
2.70	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
2.70	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
2.63	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
2.63	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
2.63	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
2.63	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
2.63	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.63	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.63	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
2.63	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
2.63	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
2.63	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
2.63	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
2.63	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
2.63	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
2.63	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
2.63	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
2.63	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
2.63	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
2.63	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.63	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.63	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
2.63	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
2.63	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.63	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.63	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
2.63	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
2.63	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
2.63	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
2.63	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
2.63	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.63	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.63	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
2.63	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
2.56	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
2.56	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
2.56	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
2.56	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
2.56	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
2.56	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
2.56	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
2.56	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.56	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
2.56	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
2.56	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
2.56	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.56	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
2.56	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.56	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
2.56	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
2.56	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
2.56	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
2.56	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
2.56	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
2.56	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
2.56	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
2.56	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
2.56	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
2.56	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
2.56	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
2.56	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
2.56	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
2.56	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
2.56	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
2.56	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
2.56	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
2.56	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
2.50	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
2.50	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
2.50	Single	6FJ3	PTH	6FJ3-PTH1-PTH
2.50	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
2.50	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
2.50	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
2.50	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
2.50	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
2.50	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
2.50	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
2.50	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
2.50	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
2.50	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
2.50	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
2.50	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
2.50	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
2.50	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
2.50	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
2.50	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
2.50	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.50	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
2.50	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
2.50	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
2.50	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
2.44	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
2.44	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
2.44	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
2.44	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
2.44	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
2.44	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
2.44	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
2.44	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
2.44	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
2.44	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
2.44	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
2.44	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
2.44	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.44	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
2.44	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
2.44	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
2.44	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
2.44	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
2.44	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
2.44	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.44	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.44	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
2.44	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
2.38	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
2.38	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
2.38	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
2.38	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
2.38	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
2.38	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
2.38	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
2.38	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
2.38	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
2.38	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
2.38	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
2.38	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
2.38	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
2.38	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
2.38	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
2.38	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
2.38	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
2.38	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
2.38	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
2.38	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
2.38	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
2.38	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
2.38	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
2.33	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
2.33	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
2.33	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
2.33	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
2.33	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
2.33	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
2.33	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
2.33	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.33	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
2.33	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
2.27	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
2.27	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
2.27	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
2.27	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
2.27	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
2.27	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
2.27	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
2.27	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
2.27	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
2.27	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
2.27	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
2.22	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
2.22	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
2.22	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.22	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
2.22	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
2.22	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
2.22	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
2.17	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
2.17	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.17	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
2.17	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
2.17	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
2.17	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
2.17	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
2.17	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
2.13	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
2.08	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.08	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.04	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
2.00	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
1.96	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
1.85	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
E:E:V227	X:X:?1	4.46	0	No	Yes	9	0	1	0
E:E:V229	W:W:?1	2.97	0	No	Yes	9	0	2	1
E:E:S230	T:T:F226	2.64	5	No	Yes	9	9	1	2
E:E:S230	W:W:?1	2.99	5	No	Yes	9	0	1	1
E:E:S230	X:X:?1	13.48	5	No	Yes	9	0	1	0
E:E:L231	E:E:L234	2.77	0	No	No	9	9	2	1
E:E:L234	X:X:?1	6.9	0	No	Yes	9	0	1	0
E:E:L237	W:W:?1	4.14	0	No	Yes	9	0	2	1
R:R:F804	R:R:W751	8.02	5	No	Yes	9	8	2	2
R:R:W751	W:W:?1	6.81	5	Yes	Yes	8	0	2	1
R:R:F804	W:W:?1	24.29	5	No	Yes	9	0	2	1
S:S:K747	S:S:W751	4.64	0	No	Yes	7	8	2	1
S:S:F804	S:S:W751	8.02	5	No	Yes	9	8	1	1
S:S:W751	T:T:L236	5.69	5	Yes	Yes	8	9	1	2
S:S:W751	T:T:I240	5.87	5	Yes	No	8	9	1	2
S:S:W751	X:X:?1	12.49	5	Yes	Yes	8	0	1	0
S:S:F804	S:S:L800	6.09	5	No	No	9	9	1	2
S:S:F804	X:X:?1	31.58	5	No	Yes	9	0	1	0
T:T:F226	T:T:S230	7.93	5	Yes	No	9	9	2	2
T:T:F226	W:W:?1	6.07	5	Yes	Yes	9	0	2	1
T:T:S230	W:W:?1	2.99	5	No	Yes	9	0	2	1
T:T:C233	X:X:?1	9.5	0	No	Yes	8	0	1	0
T:T:L234	W:W:?1	5.52	0	No	Yes	9	0	2	1
T:T:I240	T:T:L236	2.85	5	No	Yes	9	9	2	2
T:T:K241	T:T:L237	4.23	0	No	No	9	9	2	1
T:T:L237	W:W:?1	4.14	5	No	Yes	9	0	1	1
T:T:L237	X:X:?1	4.14	5	No	Yes	9	0	1	0
T:T:I240	T:T:K241	5.82	5	No	No	9	9	2	2
W:W:?1	X:X:?1	30.28	5	Yes	Yes	0	0	1	0
T:T:V229	X:X:?1	1.49	0	No	Yes	9	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
66.67	Single	8Y69	Cholesterol	8Y69-LGR4-R-spondin-2-Cholesterol-ZNRF3
14.29	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
14.29	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
13.33	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
13.33	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
13.33	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
12.50	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
11.76	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
10.00	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
9.52	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
9.09	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
9.09	Single	8ZPM	Cholesterol	8ZPM-CXCR4-AMD070-Cholesterol
7.69	Single	7EB2	rac-BHFF	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
7.69	Single	8PKM	t7m	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
6.67	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
6.25	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
6.25	Single	8PJK	t7m	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
6.25	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
5.88	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
5.88	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
5.56	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
5.56	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
5.56	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.26	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/β1/γ2
5.00	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
4.76	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
4.76	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
4.35	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
4.17	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
4.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
E:E:L131	L:L:S45	6.01	0	No	No	9	0	1	0
E:E:E127	L:L:S47	5.75	3	No	No	9	0	1	0
E:E:K125	L:L:D49	12.44	3	Yes	Yes	9	0	1	0
E:E:M192	L:L:D49	5.54	3	Yes	Yes	9	0	1	0
E:E:H102	L:L:N50	12.75	3	Yes	Yes	9	0	1	0
E:E:P103	L:L:N50	6.52	3	No	Yes	9	0	1	0
E:E:K125	L:L:N50	5.6	3	Yes	Yes	9	0	1	0
E:E:E127	L:L:N50	6.57	3	No	Yes	9	0	1	0
E:E:E127	L:L:S53	7.19	3	No	No	9	0	1	0
L:L:K58	R:R:N114	4.2	0	Yes	No	0	9	0	1
L:L:K58	R:R:H140	7.86	0	Yes	No	0	8	0	1
L:L:K58	R:R:D162	4.15	0	Yes	No	0	9	0	1
E:E:L104	L:L:F61	4.87	3	No	Yes	9	0	1	0
E:E:H102	L:L:L63	6.43	3	Yes	Yes	9	0	1	0
E:E:Y116	L:L:R65	13.38	0	Yes	No	9	0	1	0
E:E:I98	L:L:M68	7.29	3	No	No	8	0	1	0
E:E:V195	L:L:M68	3.04	3	Yes	No	9	0	1	0
E:E:A201	L:L:M68	3.22	0	No	No	9	0	1	0
E:E:N196	L:L:R69	3.62	0	No	No	9	0	1	0
E:E:H102	L:L:Q70	3.71	3	Yes	No	9	0	1	0
L:L:H76	R:R:G90	3.18	0	No	No	0	9	0	1
L:L:S77	R:R:R135	3.95	0	No	Yes	0	9	0	1
L:L:R86	R:R:D137	10.72	1	Yes	Yes	0	9	0	1
L:L:R86	R:R:A138	4.15	1	Yes	No	0	9	0	1
L:L:R86	R:R:D161	10.72	1	Yes	Yes	0	9	0	1
L:L:P88	R:R:L186	3.28	1	No	No	0	9	0	1
L:L:P88	R:R:N210	11.4	1	No	Yes	0	9	0	1
E:E:L104	L:L:M90	2.83	3	No	No	9	0	1	0
E:E:N110	L:L:R92	3.62	0	No	No	9	0	1	0
E:E:E112	L:L:R97	13.96	0	No	No	9	0	1	0
L:L:F105	R:R:W159	14.03	1	Yes	Yes	0	9	0	1
L:L:F105	R:R:A181	8.32	1	Yes	No	0	9	0	1
L:L:F105	R:R:T183	3.89	1	Yes	Yes	0	9	0	1
L:L:F105	R:R:V205	3.93	1	Yes	Yes	0	9	0	1
L:L:S106	R:R:H207	5.58	0	No	Yes	0	9	0	1
L:L:F109	R:R:H157	5.66	1	Yes	Yes	0	9	0	1
L:L:F109	R:R:Q180	3.51	1	Yes	Yes	0	9	0	1
L:L:F109	R:R:V204	6.55	1	Yes	Yes	0	9	0	1
L:L:F109	R:R:V205	5.24	1	Yes	Yes	0	9	0	1
L:L:T111	R:R:H157	6.85	0	No	Yes	0	9	0	1
L:L:R121	R:R:V204	2.62	0	No	Yes	0	9	0	1
L:L:R121	R:R:N226	8.44	0	No	No	0	8	0	1
L:L:R123	R:R:K251	4.95	0	Yes	Yes	0	9	0	1
E:E:I98	E:E:V123	3.07	3	No	No	8	9	1	2
E:E:I98	E:E:V195	4.61	3	No	Yes	8	9	1	1
E:E:V99	E:E:Y116	2.52	0	No	Yes	7	9	2	1
E:E:Q100	E:E:V195	4.3	0	No	Yes	7	9	2	1
E:E:M101	E:E:Y116	7.18	0	No	Yes	9	9	2	1
E:E:H102	E:E:P103	10.68	3	Yes	No	9	9	1	1
E:E:H102	E:E:L104	6.43	3	Yes	No	9	9	1	1
E:E:N109	E:E:N110	9.54	0	No	No	8	9	2	1
E:E:E113	E:E:N110	7.89	54	No	No	9	9	2	1
E:E:D111	E:E:E112	6.5	0	No	No	9	9	2	1
E:E:E113	E:E:R149	11.63	54	No	No	9	9	2	2
E:E:E117	E:E:Y116	4.49	0	No	Yes	9	9	2	1
E:E:R149	E:E:Y116	3.09	54	No	Yes	9	9	2	1
E:E:D157	E:E:K125	5.53	3	Yes	Yes	9	9	2	1
E:E:K125	E:E:M192	2.88	3	Yes	Yes	9	9	1	1
E:E:D157	E:E:M192	4.16	3	Yes	Yes	9	9	2	1
E:E:M192	E:E:V195	3.04	3	Yes	Yes	9	9	1	1
E:E:K197	E:E:N196	13.99	0	No	No	9	9	2	1
R:R:G90	R:R:N114	5.09	0	No	No	9	9	1	1
R:R:Q113	R:R:T111	7.09	1	Yes	No	9	9	2	2
R:R:R135	R:R:T111	9.06	1	Yes	No	9	9	1	2
R:R:Q113	R:R:R135	3.5	1	Yes	Yes	9	9	2	1
R:R:D137	R:R:Q113	3.92	1	Yes	Yes	9	9	1	2
R:R:A138	R:R:N114	4.69	1	No	No	9	9	1	1
R:R:H140	R:R:Q116	6.18	0	No	No	8	6	1	2
R:R:H157	R:R:S133	5.58	0	Yes	No	9	9	1	2
R:R:D137	R:R:R135	4.76	1	Yes	Yes	9	9	1	1
R:R:R135	R:R:W159	17.99	1	Yes	Yes	9	9	1	1
R:R:A138	R:R:D137	3.09	1	No	Yes	9	9	1	1
R:R:D137	R:R:D161	7.98	1	Yes	Yes	9	9	1	1
R:R:H157	R:R:R156	5.64	0	Yes	Yes	9	9	1	2
R:R:Q180	R:R:R156	7.01	1	Yes	Yes	9	9	1	2
R:R:H157	R:R:W159	3.17	0	Yes	Yes	9	9	1	1
R:R:A181	R:R:H157	2.93	0	No	Yes	9	9	1	1
R:R:D161	R:R:W159	4.47	1	Yes	Yes	9	9	1	1
R:R:T183	R:R:W159	3.64	1	Yes	Yes	9	9	1	1
R:R:D161	R:R:T183	7.23	1	Yes	Yes	9	9	1	1
R:R:A185	R:R:D161	4.63	0	No	Yes	9	9	2	1
R:R:D162	R:R:L186	8.14	0	No	No	9	9	1	1
R:R:Q180	R:R:V204	2.87	1	Yes	Yes	9	9	1	1
R:R:H207	R:R:T183	5.48	1	Yes	Yes	9	9	1	1
R:R:A185	R:R:H209	5.85	0	No	Yes	9	9	2	2
R:R:L186	R:R:N210	8.24	1	No	Yes	9	9	1	1
R:R:V204	R:R:V205	4.81	1	Yes	Yes	9	9	1	1
R:R:E228	R:R:V204	5.7	0	No	Yes	9	9	2	1
R:R:H207	R:R:V205	4.15	1	Yes	Yes	9	9	1	1
R:R:T229	R:R:V205	7.93	1	Yes	Yes	9	9	2	1
R:R:H207	R:R:H209	4.78	1	Yes	Yes	9	9	1	2
R:R:H207	R:R:T229	2.74	1	Yes	Yes	9	9	1	2
R:R:D231	R:R:H207	15.13	1	Yes	Yes	9	9	2	1
R:R:H209	R:R:N210	7.65	1	Yes	Yes	9	9	2	1
R:R:D231	R:R:H209	2.52	1	Yes	Yes	9	9	2	2
R:R:N210	R:R:Y234	11.63	1	Yes	No	9	6	1	2
R:R:E228	R:R:K251	10.8	0	No	Yes	9	9	2	1
R:R:D231	R:R:T229	4.34	1	Yes	Yes	9	9	2	2
R:R:E252	R:R:T229	4.23	0	No	Yes	9	9	2	2
R:R:E252	R:R:K251	6.75	0	No	Yes	9	9	2	1
R:R:K251	R:R:R275	3.71	0	Yes	No	9	5	1	2
E:E:G105	L:L:L63	1.71	0	No	Yes	9	0	1	0
E:E:A201	E:E:I194	1.62	0	No	No	9	9	1	2
R:R:Q180	R:R:S202	1.44	1	Yes	No	9	8	1	2
E:E:D114	E:E:L115	1.36	0	No	No	9	8	1	2
E:E:L131	E:E:Q128	1.33	0	No	No	9	9	1	2
E:E:L131	L:L:R54	1.21	0	No	No	9	0	1	0
E:E:D114	L:L:R65	1.19	0	No	No	9	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
71.43	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-Cholesterol-ZNRF3
68.18	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3
66.67	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3
54.55	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
5.88	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.88	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
5.88	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.88	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.88	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
5.88	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
5.88	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.88	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.88	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.88	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
5.88	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
5.88	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
5.88	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
5.88	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.88	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.88	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.88	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.88	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
5.88	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
5.88	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
5.88	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
5.88	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
5.88	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.88	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.88	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.88	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.88	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.88	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.88	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
5.88	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
5.88	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.88	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.88	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.88	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.88	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.88	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
5.88	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
5.88	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
5.88	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.88	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.88	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.88	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.88	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.88	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.88	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
5.88	Single	7XW7	K1-70	7XW7-TSH-K1-70
5.88	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.88	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.88	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.88	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.88	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.88	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.88	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.88	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.88	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.88	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.88	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.88	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.88	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
5.88	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.88	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.88	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.88	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.88	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
5.88	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
5.88	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.88	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.88	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
5.88	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
5.88	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.88	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
5.88	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
5.88	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
5.88	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
5.88	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
5.88	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
5.88	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.88	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.88	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.88	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.88	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.88	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.88	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
5.88	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
5.88	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
5.88	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
5.88	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
5.88	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
5.88	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
5.88	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
5.88	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
5.88	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
5.88	Single	8WG9	(2S)-2-amino-4-phosphonobutanoic acid	8WG9-mGlu4; mGlu2-(2S)-2-amino-4-phosphonobutanoic acid
5.88	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
5.88	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
5.88	Single	8WGC	LY379268	8WGC-mGlu4; mGlu2-LY379268
5.88	Single	8WGD	WAG/WA6	8WGD-mGlu4; mGlu2-WAG/WA6
5.88	Single	8WGD	WAG/WA6	8WGD-mGlu4; mGlu2-WAG/WA6
5.88	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.88	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.88	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8WVX	Norrin	8WVX-LGR4-Norrin
5.88	Single	8WVY	Norrin	8WVY-LGR4-Norrin
5.88	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
5.88	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
5.88	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
5.88	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
5.88	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
5.88	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
5.88	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
5.88	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
5.88	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.88	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.88	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.88	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.88	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.88	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.88	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.88	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.88	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.88	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
5.88	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.88	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.88	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.88	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
5.88	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
5.88	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
5.88	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
5.88	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
5.56	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.56	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.26	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
5.26	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
5.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
5.00	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
5.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
5.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
4.76	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
4.76	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
4.76	Single	8HS2	Fab046	8HS2-GPR20-Fab046
4.76	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
4.76	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
4.55	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
4.55	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/β1/γ2
4.55	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
4.35	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
4.35	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
4.35	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
4.35	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
4.35	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
4.35	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
4.17	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
4.17	Single	6LI0	C17	6LI0-GPR52-C17
4.17	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
4.17	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
4.17	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
4.17	Single	9B9Y	7DY	9B9Y-CB₁-7DY
4.00	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
4.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
4.00	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
4.00	Single	5U09	Taranabant	5U09-CB₁-Taranabant
4.00	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
4.00	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
4.00	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
4.00	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
4.00	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
4.00	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
4.00	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
4.00	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
4.00	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
4.00	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
4.00	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
4.00	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
4.00	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
4.00	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
4.00	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
4.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.00	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
4.00	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
4.00	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
3.85	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
3.85	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
3.85	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
3.85	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
3.85	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
3.85	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
3.85	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
3.85	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
3.85	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
3.85	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
3.85	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
3.85	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
3.70	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
3.70	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
3.70	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
3.70	Single	6D27	CAY10471	6D27-DP₂-CAY10471
3.70	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
3.70	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
3.70	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
3.70	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
3.70	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
3.70	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
3.70	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
3.70	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
3.70	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
3.70	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
3.70	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
3.70	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
3.70	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
3.70	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
3.70	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
3.70	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
3.70	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
3.70	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
3.57	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
3.57	Single	5C1M	BU72	5C1M-μ-BU72
3.57	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
3.57	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
3.57	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
3.57	Single	7C4S	S1P	7C4S-S1P₃-S1P
3.57	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
3.57	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
3.57	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.57	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
3.57	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
3.57	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
3.57	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
3.57	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.57	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.57	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
3.57	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
3.45	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
3.45	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
3.45	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
3.45	Single	5V56	TC114	5V56-SMO-TC114
3.45	Single	5V57	TC114	5V57-SMO-TC114
3.45	Single	6OS1	TRV026	6OS1-AT₁-TRV026
3.45	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
3.45	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
3.45	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
3.45	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
3.45	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
3.45	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
3.45	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
3.45	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
3.45	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
3.45	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
3.45	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
3.45	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
3.45	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
3.45	Single	8E0G	BU72	8E0G-μ-BU72
3.45	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.45	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
3.45	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
3.45	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
3.45	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
3.45	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
3.45	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
3.45	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
3.45	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
3.45	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
3.45	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
3.45	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
3.45	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
3.45	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
3.45	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
3.45	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.45	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
3.45	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
3.45	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
3.33	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
3.33	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
3.33	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
3.33	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
3.33	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
3.33	Single	6OS2	TRV026	6OS2-AT₁-TRV026
3.33	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
3.33	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
3.33	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
3.33	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
3.33	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
3.33	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.33	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
3.33	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
3.33	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
3.33	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
3.33	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.33	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
3.33	Single	8XQJ	JN241	8XQJ-Apelin-JN241
3.33	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
3.33	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
3.33	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
3.33	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
3.33	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
3.33	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
3.33	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
3.33	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
3.33	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
3.33	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.33	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
3.33	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
3.33	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
3.33	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
3.33	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
3.33	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
3.33	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
3.33	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
3.33	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
3.33	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.33	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
3.33	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
3.33	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
3.23	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
3.23	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
3.23	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
3.23	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.23	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
3.23	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
3.23	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
3.23	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
3.23	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
3.23	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
3.23	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
3.23	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
3.23	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
3.23	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
3.23	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
3.23	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
3.23	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
3.23	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
3.23	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
3.23	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
3.23	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
3.23	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
3.23	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
3.23	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
3.23	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
3.12	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
3.12	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
3.12	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
3.12	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
3.12	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
3.12	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
3.12	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
3.12	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
3.12	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
3.12	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
3.12	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
3.12	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.12	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
3.12	Single	8XQJ	JN241	8XQJ-Apelin-JN241
3.12	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
3.12	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
3.12	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
3.12	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
3.12	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
3.12	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
3.12	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
3.03	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
3.03	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
3.03	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
3.03	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
3.03	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
3.03	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
3.03	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
3.03	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
3.03	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
3.03	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
3.03	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
3.03	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
3.03	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.03	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
3.03	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
3.03	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
3.03	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
3.03	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
3.03	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
3.03	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
3.03	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
3.03	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
3.03	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
3.03	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
3.03	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
3.03	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.03	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.03	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
2.94	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
2.94	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
2.94	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
2.94	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
2.94	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
2.94	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
2.94	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
2.94	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
2.94	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
2.94	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
2.94	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
2.94	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
2.94	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
2.94	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
2.94	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
2.94	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
2.94	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
2.94	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
2.94	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
2.94	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
2.94	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
2.86	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
2.86	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
2.86	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
2.86	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
2.86	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
2.86	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
2.86	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
2.86	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
2.86	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
2.86	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
2.86	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
2.86	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
2.86	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
2.86	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
2.86	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
2.86	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
2.86	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.86	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.86	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
2.86	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
2.86	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
2.86	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
2.86	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
2.86	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
2.86	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
2.78	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
2.78	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
2.78	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
2.78	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
2.78	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.78	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.78	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
2.78	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
2.78	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
2.78	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
2.78	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
2.78	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
2.78	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
2.78	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
2.78	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
2.78	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
2.78	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
2.78	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.78	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.78	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
2.78	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
2.78	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
2.78	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.78	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
2.78	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
2.78	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
2.78	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
2.78	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
2.78	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.78	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
2.78	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
2.78	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
2.70	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
2.70	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
2.70	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
2.70	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
2.70	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
2.70	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
2.70	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
2.70	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.70	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
2.70	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
2.70	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
2.70	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.70	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
2.70	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.70	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
2.70	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
2.70	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
2.70	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
2.70	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
2.70	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
2.70	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
2.70	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
2.70	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
2.70	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
2.70	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
2.70	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
2.70	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
2.70	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
2.70	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
2.70	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
2.70	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
2.70	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
2.70	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
2.63	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
2.63	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
2.63	Single	6FJ3	PTH	6FJ3-PTH1-PTH
2.63	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
2.63	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
2.63	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
2.63	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
2.63	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
2.63	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
2.63	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
2.63	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
2.63	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
2.63	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
2.63	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
2.63	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
2.63	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
2.63	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
2.63	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
2.63	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
2.63	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
2.63	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
2.63	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
2.63	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
2.63	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
2.56	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
2.56	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
2.56	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
2.56	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
2.56	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
2.56	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
2.56	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
2.56	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
2.56	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
2.56	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
2.56	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
2.56	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
2.56	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.56	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
2.56	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
2.56	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
2.56	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
2.56	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
2.56	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
2.56	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.56	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.56	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
2.56	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
2.50	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
2.50	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
2.50	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
2.50	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
2.50	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
2.50	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
2.50	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
2.50	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
2.50	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
2.50	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
2.50	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
2.50	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
2.50	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
2.50	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
2.50	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
2.50	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
2.50	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
2.50	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
2.50	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
2.50	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
2.50	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
2.50	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
2.50	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
2.44	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
2.44	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
2.44	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
2.44	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
2.44	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
2.44	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
2.44	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
2.44	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
2.44	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
2.44	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
2.38	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
2.38	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
2.38	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
2.38	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
2.38	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
2.38	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
2.38	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
2.38	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
2.38	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
2.38	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
2.38	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
2.33	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
2.33	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
2.33	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.33	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
2.33	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
2.33	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
2.33	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
2.27	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
2.27	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.27	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
2.27	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
2.27	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
2.27	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
2.27	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
2.27	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
2.22	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
2.17	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.17	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.13	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
2.08	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
2.04	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
1.92	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
E:E:F226	T:T:F226	21.43	0	No	Yes	9	9	2	1
E:E:V227	X:X:?1	4.46	0	No	Yes	9	0	2	1
E:E:V229	W:W:?1	2.97	0	No	Yes	9	0	1	0
E:E:S230	T:T:F226	2.64	5	No	Yes	9	9	1	1
E:E:S230	W:W:?1	2.99	5	No	Yes	9	0	1	0
E:E:S230	X:X:?1	13.48	5	No	Yes	9	0	1	1
E:E:L234	X:X:?1	6.9	0	No	Yes	9	0	2	1
E:E:I240	E:E:L236	2.85	5	No	No	9	9	2	2
E:E:L236	R:R:W751	6.83	5	No	Yes	9	8	2	1
E:E:I240	E:E:L237	7.14	5	No	No	9	9	2	1
E:E:K241	E:E:L237	8.46	0	No	No	9	9	2	1
E:E:L237	W:W:?1	4.14	0	No	Yes	9	0	1	0
E:E:I240	R:R:W751	8.22	5	No	Yes	9	8	2	1
R:R:K747	R:R:W751	9.28	0	No	Yes	7	8	2	1
R:R:F804	R:R:W751	8.02	5	No	Yes	9	8	1	1
R:R:W751	W:W:?1	6.81	5	Yes	Yes	8	0	1	0
R:R:F804	R:R:L800	10.96	5	No	No	9	9	1	2
R:R:F804	W:W:?1	24.29	5	No	Yes	9	0	1	0
S:S:F804	S:S:W751	8.02	5	No	Yes	9	8	2	2
S:S:W751	X:X:?1	12.49	5	Yes	Yes	8	0	2	1
S:S:F804	X:X:?1	31.58	5	No	Yes	9	0	2	1
T:T:F226	T:T:S230	7.93	5	Yes	No	9	9	1	1
T:T:F226	W:W:?1	6.07	5	Yes	Yes	9	0	1	0
T:T:S230	W:W:?1	2.99	5	No	Yes	9	0	1	0
T:T:C233	X:X:?1	9.5	0	No	Yes	8	0	2	1
T:T:L234	W:W:?1	5.52	0	No	Yes	9	0	1	0
T:T:K241	T:T:L237	4.23	0	No	No	9	9	2	1
T:T:L237	W:W:?1	4.14	5	No	Yes	9	0	1	0
T:T:L237	X:X:?1	4.14	5	No	Yes	9	0	1	1
W:W:?1	X:X:?1	30.28	5	Yes	Yes	0	0	0	1
T:T:V229	X:X:?1	1.49	0	No	Yes	9	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
66.67	Single	8Y69	Cholesterol	8Y69-LGR4-R-spondin-2-Cholesterol-ZNRF3
15.38	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
15.38	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
14.29	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
14.29	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
14.29	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
13.33	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
12.50	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
10.53	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
10.00	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
10.00	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
10.00	Single	8ZPM	Cholesterol	8ZPM-CXCR4-AMD070-Cholesterol
8.33	Single	7EB2	rac-BHFF	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
8.33	Single	8PKM	t7m	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
7.14	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
6.67	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
6.67	Single	8PJK	t7m	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
6.67	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
6.25	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
6.25	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
5.88	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
5.88	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
5.88	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.56	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/β1/γ2
5.26	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
5.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
5.00	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
4.76	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
4.55	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
4.35	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
4.17	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2

PDB Summary
PDB	8Y69
Class	A
SubFamily	Orphan
Type	Orphan
SubType	LGR4
Species	Homo Sapiens
Ligand	R-spondin-2
Other Ligand(s)	Cholesterol
Protein Partners	ZNRF3
PDB Resolution	3.38
Date	2024-12-04
D.O.I.	To be published

Net Summary
I_min	2.51
Number of Linked Nodes	1939
Number of Links	2410
Number of Hubs	401
Number of Links mediated by Hubs	1413
Number of Communities	89
Number of Nodes involved in Communities	582
Number of Links involved in Communities	787

Path Summary
Number Of Nodes in MetaPath	1106
Number Of Links MetaPath	1105
Number of Shortest Paths	-2035775492
Length Of Smallest Path	3
Average Path Length	128
Length of Longest Path	103
Minimum Path Strength	1.27
Average Path Strength	8.16375
Maximum Path Strength	30.93
Minimum Path Correlation	0.72
Average Path Correlation	1
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	123.415
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	106.959
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• multicellular organismal process • tissue remodeling • bone remodeling • developmental process • epithelium development • cell population proliferation • tube development • morphogenesis of an epithelium • tissue development • renal system development • epithelial cell proliferation involved in renal tubule morphogenesis • tissue morphogenesis • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • anatomical structure development • renal tubule development • cellular process • epithelial tube morphogenesis • epithelial cell proliferation • renal tubule morphogenesis • system development • cellular developmental process • ossification • cell differentiation • osteoblast differentiation • cellular response to stimulus • positive regulation of response to biotic stimulus • regulation of cellular process • pattern recognition receptor signaling pathway • response to stimulus • toll-like receptor signaling pathway • negative regulation of biological process • regulation of signal transduction • response to biotic stimulus • cell communication • immune response-activating signaling pathway • positive regulation of immune response • regulation of immune system process • signal transduction • positive regulation of immune system process • innate immune response-activating signaling pathway • regulation of biological process • immune response • response to other organism • regulation of innate immune response • response to external stimulus • regulation of response to stimulus • defense response to other organism • regulation of pattern recognition receptor signaling pathway • positive regulation of defense response • activation of innate immune response • regulation of immune response • regulation of toll-like receptor signaling pathway • activation of immune response • regulation of defense response • regulation of response to biotic stimulus • biological process involved in interspecies interaction between organisms • regulation of response to external stimulus • signaling • negative regulation of signaling • positive regulation of biological process • negative regulation of cell communication • positive regulation of response to stimulus • positive regulation of response to external stimulus • immune response-regulating signaling pathway • regulation of response to stress • response to stress • innate immune response • negative regulation of cellular process • response to external biotic stimulus • regulation of signaling • positive regulation of innate immune response • defense response • negative regulation of response to stimulus • biological regulation • defense response to symbiont • negative regulation of signal transduction • negative regulation of toll-like receptor signaling pathway • negative regulation of immune system process • immune system process • regulation of cell communication • spermatogenesis • sexual reproduction • reproductive process • multicellular organismal reproductive process • developmental process involved in reproduction • male gamete generation • gamete generation • bone mineralization • animal organ development • biomineral tissue development • mesonephric epithelium development • kidney epithelium development • branching morphogenesis of an epithelial tube • nephron tubule morphogenesis • regulation of kidney development • regulation of branching involved in ureteric bud morphogenesis • positive regulation of developmental process • animal organ morphogenesis • nephron development • regulation of morphogenesis of a branching structure • regulation of animal organ morphogenesis • positive regulation of multicellular organismal process • mesonephric tubule development • regulation of developmental process • nephron morphogenesis • nephron epithelium morphogenesis • nephron tubule development • ureteric bud morphogenesis • positive regulation of morphogenesis of an epithelium • branching involved in ureteric bud morphogenesis • regulation of morphogenesis of an epithelium • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • nephron epithelium development • ureteric bud development • mesonephros development • kidney morphogenesis • morphogenesis of a branching structure • positive regulation of branching involved in ureteric bud morphogenesis • mesonephric tubule morphogenesis • kidney development • morphogenesis of a branching epithelium • digestive system development • digestive tract development • epidermis development • molting cycle process • hair cycle • skin development • skin epidermis development • hair follicle development • molting cycle • hair cycle process • genitalia development • reproductive system development • sex differentiation • male sex differentiation • male genitalia development • reproductive structure development • multicellular organismal-level homeostasis • homeostatic process • homeostasis of number of cells • intestinal stem cell homeostasis • regulation of biosynthetic process • rhythmic process • circadian regulation of gene expression • circadian rhythm • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • regulation of metabolic process • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cytokine production • regulation of cytokine production • negative regulation of macromolecule metabolic process • negative regulation of metabolic process • negative regulation of cytokine production • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of multicellular organismal process • metanephric tubule morphogenesis • metanephric epithelium development • metanephros development • metanephros morphogenesis • metanephric nephron tubule morphogenesis • metanephric nephron development • metanephric nephron epithelium development • metanephric nephron tubule development • metanephric nephron morphogenesis • metanephric tubule development • cell surface receptor signaling pathway • Wnt signaling pathway • positive regulation of cell communication • positive regulation of signal transduction • regulation of canonical Wnt signaling pathway • canonical Wnt signaling pathway • positive regulation of Wnt signaling pathway • positive regulation of cellular process • positive regulation of canonical Wnt signaling pathway • regulation of Wnt signaling pathway • positive regulation of signaling • negative regulation of cold-induced thermogenesis • adaptive thermogenesis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • metanephric glomerulus development • glomerulus development • cell periphery • cellular anatomical structure • plasma membrane • membrane • aminoacyltransferase activity • ubiquitin-like protein transferase activity • catalytic activity, acting on a protein • acyltransferase activity • transferase activity • catalytic activity • ubiquitin-protein transferase activity • ubiquitin-like protein ligase activity • ubiquitin protein ligase activity • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • frizzled binding • cation binding • ion binding • metal ion binding • small molecule binding • catabolic process • proteolysis involved in protein catabolic process • primary metabolic process • protein catabolic process • macromolecule catabolic process • modification-dependent macromolecule catabolic process • modification-dependent protein catabolic process • proteolysis • ubiquitin-dependent protein catabolic process • protein metabolic process • limb development • appendage development • stem cell proliferation • regulation of Wnt signaling pathway, planar cell polarity pathway • Wnt signaling pathway, planar cell polarity pathway • regulation of non-canonical Wnt signaling pathway • non-canonical Wnt signaling pathway • receptor catabolic process • negative regulation of Wnt signaling pathway • receptor metabolic process • Wnt receptor catabolic process • negative regulation of canonical Wnt signaling pathway • protein ubiquitination • macromolecule modification • post-translational protein modification • protein modification process • protein modification by small protein conjugation • protein modification by small protein conjugation or removal • negative regulation of non-canonical Wnt signaling pathway • BMP receptor binding • receptor serine/threonine kinase binding • transmembrane receptor protein serine/threonine kinase binding • heparin binding • glycosaminoglycan binding • carbohydrate derivative binding • sulfur compound binding • regulation of odontogenesis of dentin-containing tooth • negative regulation of developmental process • regulation of odontogenesis • odontogenesis of dentin-containing tooth • odontogenesis • negative regulation of odontogenesis • negative regulation of odontogenesis of dentin-containing tooth • negative regulation of animal organ morphogenesis • lung growth • developmental growth • growth • respiratory tube development • organ growth • lung development • respiratory system development • trachea cartilage morphogenesis • connective tissue development • trachea cartilage development • trachea morphogenesis • skeletal system development • trachea development • cartilage morphogenesis • cartilage development • embryonic forelimb morphogenesis • embryonic limb morphogenesis • embryonic morphogenesis • embryonic appendage morphogenesis • embryo development • forelimb morphogenesis • appendage morphogenesis • limb morphogenesis • lung morphogenesis • epithelial tube branching involved in lung morphogenesis • embryonic hindlimb morphogenesis • hindlimb morphogenesis • dopaminergic neuron differentiation • nervous system development • generation of neurons • neurogenesis • neuron differentiation • cell surface • extracellular region • extracellular space
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	CLR
PDB Residues	W:W:?1 X:X:?1
Environment Details	Open EMBL-EBI Page
Code	CLR
Name	Cholesterol
Synonyms	(3β,14β,17α)-cholest-5-en-3-ol Cholesterol Cholest-5-en-3beta-ol Cholesterin
Identifier
Formula	C27 H46 O
Molecular Weight	386.654
SMILES
PubChem	5997
Formal Charge	0
Total Atoms	74
Total Chiral Atoms	8
Total Bonds	77
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BXB1
Sequence	>8Y69_Chain_R C S C D G D R R V D C S G K G L T A V P E G L S A F T Q A L D I S M N N I T Q L P E D A F N F P F L E E L Q L A G N D L S F I H P K A L S G L K E L K V L T L Q N N Q L K T V P S E A I R G L S A L Q S L R L D A N H I T S V P E D S F E G L V Q L R H L W L D D N S L T E V P V H P L S N L P T L Q A L T L A L N K I S S I P D F A F T N L S S L V V L H L H N N K I R S L S Q H C F D G L D N L E T L D L N Y N N L G E F P Q A I K A L P S L K E L G F H S N S I S V I P D G A F D G N P L L R T I H L Y D N P L S F V G N S A F H N L S D L H S L V I R G A S M V Q Q F P N L T G T V H L E S L T L T G T K I S S I P N N L C Q E Q K M L R T L D L S Y N N I R D L P S F N G C H A L E E I S L Q R N Q I Y Q I K E G T F Q G L I S L R I L D L S R N L I H E I H S R A F A T L G P I T N L D V S F N E L T S F P T E G L N G L N Q L K L V G N F K L K E A L A A K D F V N L R S L S V P Y A Y Q C C A F W G C I I I H C T P S T G A F K P C E Y L L G S W M I R L T V W F I F L V A L F F N L L V I L T T F L P S S K L F I G L I S V S N L F M G I Y T G I L T F L D A V S W G R F A E F G I W W E T G S G C K V A G F L A V F S S E S A I F L L M L A T V E R S L S A K D N H L K Q F R V A A L L A F L G A T V A G C F P L F H R G E Y S A S P L C L P F P T G E T P S L G F T V T L V L L N S L A F L L M A V I Y T K L Y C N L E E N S Q S S M I K H V A W L I F T N C I F F C P V A F F S F A P L I T A I S I S P E I M K S V T L I F F P L P A C L N P V L Y V F F N P K F K E D W K L L K R R V T A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q9BXB1
Sequence	>8Y69_Chain_S C S C D G D R R V D C S G K G L T A V P E G L S A F T Q A L D I S M N N I T Q L P E D A F N F P F L E E L Q L A G N D L S F I H P K A L S G L K E L K V L T L Q N N Q L K T V P S E A I R G L S A L Q S L R L D A N H I T S V P E D S F E G L V Q L R H L W L D D N S L T E V P V H P L S N L P T L Q A L T L A L N K I S S I P D F A F T N L S S L V V L H L H N N K I R S L S Q H C F D G L D N L E T L D L N Y N N L G E F P Q A I K A L P S L K E L G F H S N S I S V I P D G A F D G N P L L R T I H L Y D N P L S F V G N S A F H N L S D L H S L V I R G A S M V Q Q F P N L T G T V H L E S L T L T G T K I S S I P N N L C Q E Q K M L R T L D L S Y N N I R D L P S F N G C H A L E E I S L Q R N Q I Y Q I K E G T F Q G L I S L R I L D L S R N L I H E I H S R A F A T L G P I T N L D V S F N E L T S F P T E G L N G L N Q L K L V G N F K L K E A L A A K D F V N L R S L S V P Y A Y Q C C A F W G C I I I H C T P S T G A F K P C E Y L L G S W M I R L T V W F I F L V A L F F N L L V I L T T F A T S L P S S K L F I G L I S V S N L F M G I Y T G I L T F L D A V S W G R F A E F G I W W E T G S G C K V A G F L A V F S S E S A I F L L M L A T V E R S L S A K D N H L K Q F R V A A L L A F L G A T V A G C F P L F H R G E Y S A S P L C L P F P T G E T P S L G F T V T L V L L N S L A F L L M A V I Y T K L Y C N L E E N S Q S S M I K H V A W L I F T N C I F F C P V A F F S F A P L I T A I S I S P E I M K S V T L I F F P L P A C L N P V L Y V F F N P K F K E D W K L L K R R V T A C A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	T
Protein	ZNRF3
UniProt	Q9ULT6
Sequence	>8Y69_Chain_T K E T A F V E V V L F E T T Y T T G L T G R F S R A G A T L S A E G E I V Q M H P L G L C N N N D E E D L Y E Y G W V G V V K L E Q P E L D P K P C L T V L G K A K R A V Q R G A T A V I F D V S E N P E A I D Q L N Q G S E D P L K R P V V Y V K G A D A I K L M N I V N K Q K V A R A R I Q H R P P R Q E Y F D M G I F L A F F V V V S L V C L I L L V K I K L K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8XUM	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	-	2.9	2025-01-15	To be published
	8XT9	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.1	2025-01-15	To be published
	8Y69	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	Cholesterol	ZNRF3	3.38	2024-12-04	To be published
	8XFT	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.24	2024-12-04	To be published
	8XFS	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.2	2024-12-04	To be published
	8XFP	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.21	2024-12-04	To be published
	8WVY	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.29	2024-10-30	To be published
	8WVW	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.53	2024-10-30	To be published
	8WVV	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.35	2024-10-30	To be published
	8WVU	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-1	-	RNF43	3.61	2024-10-30	To be published
	8WVX	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.32	2024-10-30	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8Y69.zip

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