psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:D1	L:L:P100	9.66	No	No	0	0	0
2	L:L:Q27	L:L:V2	4.3	No	No	1	0	0
3	L:L:Q95	L:L:V2	2.87	Yes	No	1	0	0
4	L:L:H98	L:L:V2	4.15	No	No	1	0	0
5	L:L:S26	L:L:V3	3.23	No	No	0	0	0
6	L:L:C23	L:L:M4	3.24	Yes	Yes	1	0	0
7	L:L:M4	L:L:S25	3.07	Yes	No	0	0	0
8	L:L:L38	L:L:M4	2.83	No	Yes	0	0	0
9	L:L:M4	L:L:Q95	4.08	Yes	Yes	1	0	0
10	L:L:M4	L:L:T102	3.01	Yes	No	1	0	0
11	L:L:I21	L:L:Q6	2.74	No	Yes	1	0	0
12	L:L:C23	L:L:Q6	4.58	Yes	Yes	1	0	0
13	L:L:Q6	L:L:W40	2.19	Yes	Yes	1	0	0
14	L:L:C93	L:L:Q6	4.58	No	Yes	1	0	0
15	L:L:G106	L:L:Q6	3.29	Yes	Yes	1	0	0
16	L:L:Q6	L:L:T107	5.67	Yes	No	1	0	0
17	L:L:L11	L:L:P8	3.28	No	No	0	0	0
18	L:L:P12	L:L:S10	1.78	No	No	0	0	0
19	L:L:E110	L:L:S10	4.31	Yes	No	0	0	0
20	L:L:K112	L:L:P12	6.69	No	No	0	0	0
21	L:L:V13	L:L:V83	6.41	No	No	0	0	0
22	L:L:Q17	L:L:T14	4.25	No	No	0	0	0
23	L:L:K112	L:L:T14	6.01	No	No	0	0	0
24	L:L:I111	L:L:L15	2.85	No	No	0	0	0
25	L:L:P18	L:L:Q17	3.16	No	No	0	0	0
26	L:L:I21	L:L:W40	4.7	No	Yes	1	0	0
27	L:L:I21	L:L:T107	12.16	No	No	1	0	0
28	L:L:S22	L:L:T77	6.4	No	No	0	0	0
29	L:L:C23	L:L:W40	6.53	Yes	Yes	1	0	0
30	L:L:C23	L:L:C93	7.28	Yes	No	1	0	0
31	L:L:D75	L:L:R24	8.34	No	No	0	0	0
32	L:L:L29	L:L:S25	6.01	No	No	0	0	0
33	L:L:S25	L:L:T74	4.8	No	No	0	0	0
34	L:L:Q27	L:L:S26	2.89	No	No	0	0	0
35	L:L:H98	L:L:Q27	2.47	No	No	1	0	0
36	L:L:S28	L:L:V30	6.46	No	No	0	0	0
37	L:L:F76	L:L:L29	2.44	No	No	0	0	0
38	L:L:L29	L:L:Q95	6.65	No	Yes	0	0	0
39	L:L:T32	L:L:Y31	2.5	No	No	0	0	0
40	L:L:D33	L:L:Y31	6.9	No	No	0	0	0
41	L:L:Y31	M:M:Y109	2.98	No	No	0	0	0
42	L:L:D33	L:L:Y37	3.45	No	Yes	0	0	0
43	L:L:D33	R:R:E32	5.2	No	No	0	0	4
44	L:L:N35	L:L:Y37	5.81	No	Yes	1	0	0
45	L:L:K55	L:L:N35	5.6	Yes	No	1	0	0
46	L:L:T36	L:L:V56	3.17	No	No	0	0	0
47	L:L:K55	L:L:Y37	4.78	Yes	Yes	1	0	0
48	L:L:T97	L:L:Y37	3.75	No	Yes	0	0	0
49	L:L:Y37	M:M:H110	16.33	Yes	No	1	0	0
50	L:L:L38	L:L:W40	3.42	No	Yes	0	0	0
51	L:L:F76	L:L:L38	10.96	No	No	0	0	0
52	L:L:F41	L:L:N39	4.83	Yes	No	1	0	0
53	L:L:N39	L:L:R51	3.62	No	Yes	1	0	0
54	L:L:M94	L:L:N39	8.41	Yes	No	1	0	0
55	L:L:I53	L:L:W40	8.22	Yes	Yes	1	0	0
56	L:L:L78	L:L:W40	18.22	No	Yes	1	0	0
57	L:L:C93	L:L:W40	14.37	No	Yes	1	0	0
58	L:L:F41	L:L:R51	5.34	Yes	Yes	1	0	0
59	L:L:F41	L:L:M94	6.22	Yes	Yes	1	0	0
60	L:L:F103	L:L:F41	5.36	Yes	Yes	1	0	0
61	L:L:F41	M:M:W116	4.01	Yes	Yes	1	0	0
62	L:L:Q42	L:L:R44	5.84	Yes	No	0	0	0
63	L:L:Q42	L:L:R50	3.5	Yes	No	1	0	0
64	L:L:L52	L:L:Q42	7.99	Yes	Yes	1	0	0
65	L:L:Q42	L:L:Y91	12.4	Yes	Yes	1	0	0
66	L:L:P49	L:L:Q43	11.05	Yes	No	1	0	0
67	L:L:Q43	L:L:Y92	5.64	No	Yes	1	0	0
68	L:L:Q43	M:M:Q39	11.52	No	Yes	1	0	0
69	L:L:P45	L:L:R44	4.32	No	No	0	0	0
70	L:L:Q47	L:L:R44	2.34	No	No	0	0	0
71	L:L:G89	L:L:P45	2.03	No	No	0	0	0
72	L:L:P49	L:L:S48	3.56	Yes	No	1	0	0
73	L:L:S48	M:M:Y95	2.54	No	Yes	1	0	0
74	L:L:P49	M:M:Y95	5.56	Yes	Yes	1	0	0
75	L:L:P49	M:M:W116	10.81	Yes	Yes	1	0	0
76	L:L:L52	L:L:R50	3.64	Yes	No	1	0	0
77	L:L:R50	L:L:V63	6.54	No	Yes	1	0	0
78	L:L:R51	L:L:Y54	14.4	Yes	Yes	1	0	0
79	L:L:D60	L:L:R51	2.38	No	Yes	1	0	0
80	L:L:R51	M:M:G112	3	Yes	No	1	0	0
81	L:L:R51	M:M:D114	4.76	Yes	No	0	0	0
82	L:L:R51	R:R:D181	8.34	Yes	No	1	0	2
83	L:L:L52	L:L:V63	2.98	Yes	Yes	1	0	0
84	L:L:F67	L:L:L52	7.31	Yes	Yes	1	0	0
85	L:L:L52	L:L:Y91	2.34	Yes	Yes	1	0	0
86	L:L:I53	L:L:R59	3.76	Yes	No	0	0	0
87	L:L:G69	L:L:I53	1.76	No	Yes	0	0	0
88	L:L:I53	L:L:L78	4.28	Yes	No	1	0	0
89	L:L:K55	L:L:Y54	2.39	Yes	Yes	1	0	0
90	L:L:N58	L:L:Y54	8.14	No	Yes	1	0	0
91	L:L:D60	L:L:Y54	2.3	No	Yes	1	0	0
92	L:L:Y54	R:R:D182	2.3	Yes	No	1	0	6
93	L:L:K55	L:L:N58	2.8	Yes	No	1	0	0
94	L:L:K55	R:R:D182	8.3	Yes	No	1	0	6
95	L:L:F76	L:L:V56	3.93	No	No	0	0	0
96	L:L:R59	L:L:V63	6.54	No	Yes	0	0	0
97	L:L:D65	L:L:R59	5.96	No	No	0	0	0
98	L:L:D60	L:L:V63	5.84	No	Yes	1	0	0
99	L:L:P64	L:L:V63	5.3	No	Yes	1	0	0
100	L:L:F67	L:L:V63	2.62	Yes	Yes	1	0	0
101	L:L:P64	L:L:R66	8.65	No	Yes	1	0	0
102	L:L:F67	L:L:P64	5.78	Yes	No	1	0	0
103	L:L:F67	L:L:R66	3.21	Yes	Yes	1	0	0
104	L:L:R66	L:L:S81	2.64	Yes	No	0	0	0
105	L:L:R66	L:L:R82	4.26	Yes	No	1	0	0
106	L:L:E84	L:L:R66	18.61	No	Yes	1	0	0
107	L:L:D87	L:L:R66	10.72	Yes	Yes	1	0	0
108	L:L:F67	L:L:I80	2.51	Yes	Yes	1	0	0
109	L:L:D87	L:L:F67	8.36	Yes	Yes	1	0	0
110	L:L:F67	L:L:Y91	4.13	Yes	Yes	1	0	0
111	L:L:G69	L:L:S68	1.86	No	No	0	0	0
112	L:L:K79	L:L:S68	3.06	No	No	0	0	0
113	L:L:G69	L:L:S70	3.71	No	No	0	0	0
114	L:L:G71	L:L:S70	1.86	No	No	0	0	0
115	L:L:K79	L:L:S70	4.59	No	No	0	0	0
116	L:L:G71	L:L:S72	1.86	No	No	0	0	0
117	L:L:G73	L:L:S72	3.71	No	No	0	0	0
118	L:L:K79	L:L:T77	3	No	No	0	0	0
119	L:L:I80	L:L:L78	2.85	Yes	No	1	0	0
120	L:L:I80	L:L:V83	3.07	Yes	No	1	0	0
121	L:L:D87	L:L:I80	4.2	Yes	Yes	1	0	0
122	L:L:E84	L:L:R82	5.82	No	No	1	0	0
123	L:L:D87	L:L:V83	4.38	Yes	No	1	0	0
124	L:L:D87	L:L:Y91	2.3	Yes	Yes	1	0	0
125	L:L:F90	L:L:Y92	9.28	No	Yes	0	0	0
126	L:L:F90	L:L:K108	8.69	No	No	0	0	0
127	L:L:V109	L:L:Y91	3.79	No	Yes	0	0	0
128	L:L:G106	L:L:Y92	4.35	Yes	Yes	1	0	0
129	L:L:Y92	M:M:Q39	2.25	Yes	Yes	1	0	0
130	L:L:Y92	M:M:I45	3.63	Yes	No	1	0	0
131	L:L:L101	L:L:M94	7.07	Yes	Yes	1	0	0
132	L:L:F103	L:L:M94	12.44	Yes	Yes	1	0	0
133	L:L:M94	M:M:M113	5.78	Yes	Yes	1	0	0
134	L:L:Q95	L:L:T97	2.83	Yes	No	0	0	0
135	L:L:Q95	L:L:T102	5.67	Yes	No	1	0	0
136	L:L:L101	L:L:N96	4.12	Yes	No	1	0	0
137	L:L:N96	M:M:H99	7.65	No	Yes	1	0	0
138	L:L:H98	L:L:T97	8.21	No	No	0	0	0
139	L:L:W99	M:M:W47	4.69	Yes	Yes	0	0	0
140	L:L:W99	M:M:W50	4.69	Yes	Yes	1	0	0
141	L:L:W99	M:M:N59	11.3	Yes	No	1	0	0
142	L:L:W99	M:M:Y109	10.61	Yes	No	1	0	0
143	L:L:W99	R:R:F29	4.01	Yes	Yes	1	0	4
144	L:L:P100	M:M:W47	8.11	No	Yes	0	0	0
145	L:L:F103	L:L:L101	3.65	Yes	Yes	1	0	0
146	L:L:L101	M:M:W47	6.83	Yes	Yes	0	0	0
147	L:L:L101	M:M:H99	3.86	Yes	Yes	1	0	0
148	L:L:L101	M:M:M113	2.83	Yes	Yes	1	0	0
149	L:L:F103	M:M:I45	11.3	Yes	No	1	0	0
150	L:L:G104	L:L:G105	2.11	No	No	0	0	0
151	L:L:G105	L:L:G106	2.11	No	Yes	0	0	0
152	L:L:G106	L:L:T107	1.82	Yes	No	1	0	0
153	L:L:E110	L:L:K108	4.05	Yes	No	0	0	0
154	L:L:E170	L:L:K108	8.1	No	No	0	0	0
155	L:L:E110	L:L:Q171	3.82	Yes	No	7	0	0
156	L:L:E110	L:L:Y178	5.61	Yes	Yes	7	0	0
157	L:L:I111	L:L:Q171	5.49	No	No	0	0	0
158	L:L:K112	L:L:Y145	4.78	No	No	0	0	0
159	L:L:R113	L:L:T114	3.88	Yes	No	0	0	0
160	L:L:R113	L:L:Y145	5.14	Yes	No	0	0	0
161	L:L:D175	L:L:R113	2.38	Yes	Yes	16	0	0
162	L:L:R113	L:L:S176	5.27	Yes	No	0	0	0
163	L:L:R113	L:L:T177	6.47	Yes	Yes	16	0	0
164	L:L:P146	L:L:V115	1.77	Yes	No	0	0	0
165	L:L:Q204	L:L:V115	5.73	No	No	7	0	0
166	L:L:G205	L:L:V115	1.84	No	No	7	0	0
167	L:L:A117	L:L:P118	1.87	No	Yes	0	0	0
168	L:L:F144	L:L:P118	4.33	Yes	Yes	7	0	0
169	L:L:H203	L:L:P118	13.73	Yes	Yes	7	0	0
170	L:L:L206	L:L:P118	8.21	No	Yes	7	0	0
171	L:L:F121	L:L:S119	3.96	Yes	No	0	0	0
172	L:L:V120	L:L:V201	4.81	No	Yes	7	0	0
173	L:L:V120	L:L:V210	4.81	No	No	7	0	0
174	L:L:F121	L:L:F123	2.14	Yes	Yes	0	0	0
175	L:L:F121	L:L:L140	6.09	Yes	No	0	0	0
176	L:L:F121	M:M:A150	2.77	Yes	No	0	0	0
177	L:L:C139	L:L:I122	3.27	Yes	Yes	7	0	0
178	L:L:C199	L:L:I122	3.27	Yes	Yes	7	0	0
179	L:L:I122	L:L:K212	4.36	Yes	No	0	0	0
180	L:L:F214	L:L:I122	3.77	Yes	Yes	0	0	0
181	L:L:F123	L:L:V138	3.93	Yes	No	0	0	0
182	L:L:F123	M:M:L137	13.4	Yes	No	0	0	0
183	L:L:F123	M:M:P139	2.89	Yes	Yes	0	0	0
184	L:L:F123	M:M:V194	2.62	Yes	No	0	0	0
185	L:L:P124	L:L:P125	1.95	Yes	No	0	0	0
186	L:L:F214	L:L:P124	5.78	Yes	Yes	0	0	0
187	L:L:C219	L:L:P124	1.88	No	Yes	19	0	0
188	L:L:P124	M:M:C140	3.77	Yes	No	19	0	0
189	L:L:P125	L:L:V137	3.53	No	Yes	0	0	0
190	L:L:P125	L:L:Y191	5.56	No	Yes	0	0	0
191	L:L:D127	L:L:S126	5.89	No	No	14	0	0
192	L:L:E128	L:L:S126	10.06	Yes	No	14	0	0
193	L:L:Q129	L:L:S126	5.78	No	No	14	0	0
194	L:L:D127	L:L:E128	5.2	No	Yes	14	0	0
195	L:L:D127	L:L:K131	9.68	No	No	0	0	0
196	L:L:E128	L:L:Q129	14.02	Yes	No	14	0	0
197	L:L:E128	M:M:F135	10.49	Yes	Yes	14	0	0
198	L:L:E128	M:M:P136	4.72	Yes	No	0	0	0
199	L:L:Q129	M:M:F135	17.57	No	Yes	14	0	0
200	L:L:K188	L:L:L130	4.23	No	No	0	0	0
201	L:L:L130	L:L:Y191	2.34	No	Yes	0	0	0
202	L:L:G133	L:L:T134	1.82	No	No	0	0	0
203	L:L:G133	L:L:K188	3.49	No	No	0	0	0
204	L:L:T134	M:M:K156	4.5	No	No	0	0	0
205	L:L:A135	L:L:Y191	4	No	Yes	0	0	0
206	L:L:S136	L:L:T185	3.2	No	No	0	0	0
207	L:L:V137	L:L:W153	4.9	Yes	Yes	7	0	0
208	L:L:L184	L:L:V137	4.47	Yes	Yes	7	0	0
209	L:L:F214	L:L:V137	2.62	Yes	Yes	0	0	0
210	L:L:T183	L:L:V138	3.17	No	No	0	0	0
211	L:L:C139	L:L:V151	1.71	Yes	Yes	7	0	0
212	L:L:C139	L:L:W153	5.22	Yes	Yes	7	0	0
213	L:L:C139	L:L:S182	1.72	Yes	No	7	0	0
214	L:L:C139	L:L:C199	7.28	Yes	Yes	7	0	0
215	L:L:C139	L:L:V201	1.71	Yes	Yes	7	0	0
216	L:L:L140	M:M:F179	2.44	No	Yes	0	0	0
217	L:L:F144	L:L:L141	2.44	Yes	No	7	0	0
218	L:L:L141	L:L:V151	4.47	No	Yes	7	0	0
219	L:L:L141	L:L:V201	4.47	No	Yes	7	0	0
220	L:L:N142	L:L:N143	4.09	No	No	0	0	0
221	L:L:N142	M:M:H177	3.83	No	No	0	0	0
222	L:L:N143	L:L:T177	10.24	No	Yes	0	0	0
223	L:L:A149	L:L:F144	2.77	No	Yes	0	0	0
224	L:L:F144	L:L:Y178	4.13	Yes	Yes	7	0	0
225	L:L:F144	L:L:L180	2.44	Yes	Yes	7	0	0
226	L:L:F144	L:L:H203	2.26	Yes	Yes	7	0	0
227	L:L:P146	L:L:Y145	12.52	Yes	No	0	0	0
228	L:L:E148	L:L:P146	3.14	No	Yes	0	0	0
229	L:L:H203	L:L:P146	4.58	Yes	Yes	0	0	0
230	L:L:R147	L:L:V168	13.08	No	No	7	0	0
231	L:L:R147	L:L:Y178	5.14	No	Yes	7	0	0
232	L:L:L180	L:L:R147	2.43	Yes	No	7	0	0
233	L:L:K150	L:L:Q152	2.71	No	No	0	0	0
234	L:L:K150	L:L:T202	7.51	No	No	0	0	0
235	L:L:S182	L:L:V151	3.23	No	Yes	7	0	0
236	L:L:C199	L:L:V151	1.71	Yes	Yes	7	0	0
237	L:L:V151	L:L:V201	6.41	Yes	Yes	7	0	0
238	L:L:L159	L:L:Q152	9.32	No	No	0	0	0
239	L:L:S164	L:L:W153	2.47	No	Yes	0	0	0
240	L:L:S182	L:L:W153	9.88	No	Yes	7	0	0
241	L:L:L184	L:L:W153	19.36	Yes	Yes	7	0	0
242	L:L:C199	L:L:W153	5.22	Yes	Yes	7	0	0
243	L:L:K154	L:L:L159	4.23	No	No	0	0	0
244	L:L:E200	L:L:K154	4.05	No	No	0	0	0
245	L:L:Q160	L:L:V155	10.03	No	No	0	0	0
246	L:L:H194	L:L:V155	8.3	Yes	No	12	0	0
247	L:L:V155	L:L:Y197	8.83	No	Yes	12	0	0
248	L:L:D156	L:L:H194	13.87	No	Yes	0	0	0
249	L:L:D156	L:L:V196	4.38	No	No	0	0	0
250	L:L:G162	L:L:S161	3.71	No	No	0	0	0
251	L:L:L184	L:L:N163	4.12	Yes	No	7	0	0
252	L:L:L186	L:L:N163	2.75	No	No	7	0	0
253	L:L:Q165	L:L:T183	2.83	No	No	0	0	0
254	L:L:E166	L:L:L180	5.3	No	Yes	0	0	0
255	L:L:S167	M:M:V182	3.23	No	No	0	0	0
256	L:L:L180	L:L:V168	2.98	Yes	No	7	0	0
257	L:L:S179	L:L:T169	4.8	No	No	20	0	0
258	L:L:T169	M:M:F179	3.89	No	Yes	20	0	0
259	L:L:T169	M:M:P180	1.75	No	No	0	0	0
260	L:L:Q171	L:L:Y178	15.78	No	Yes	7	0	0
261	L:L:D172	L:L:D175	2.66	No	Yes	16	0	0
262	L:L:D172	L:L:T177	4.34	No	Yes	16	0	0
263	L:L:D175	L:L:K174	2.77	Yes	No	0	0	0
264	L:L:D175	L:L:T177	2.89	Yes	Yes	16	0	0
265	L:L:S179	M:M:F179	6.61	No	Yes	20	0	0
266	L:L:S181	M:M:F179	6.61	No	Yes	0	0	0
267	L:L:L184	L:L:L186	4.15	Yes	No	7	0	0
268	L:L:D190	L:L:L186	5.43	No	No	0	0	0
269	L:L:A189	L:L:S187	1.71	No	No	0	0	0
270	L:L:D190	L:L:S187	4.42	No	No	0	0	0
271	L:L:E192	L:L:Y191	2.24	No	Yes	12	0	0
272	L:L:Y191	L:L:Y197	15.89	Yes	Yes	12	0	0
273	L:L:R216	L:L:Y191	5.14	Yes	Yes	12	0	0
274	L:L:E192	L:L:R216	5.82	No	Yes	12	0	0
275	L:L:H194	L:L:K193	13.1	Yes	No	0	0	0
276	L:L:H194	L:L:Y197	3.27	Yes	Yes	12	0	0
277	L:L:K195	L:L:N215	5.6	No	No	0	0	0
278	L:L:K195	L:L:R216	7.43	No	Yes	0	0	0
279	L:L:S213	L:L:V196	3.23	No	No	0	0	0
280	L:L:N215	L:L:V196	2.96	No	No	0	0	0
281	L:L:F214	L:L:Y197	9.28	Yes	Yes	0	0	0
282	L:L:R216	L:L:Y197	5.14	Yes	Yes	12	0	0
283	L:L:A198	L:L:S213	3.42	No	No	0	0	0
284	L:L:C199	L:L:V201	1.71	Yes	Yes	7	0	0
285	L:L:E200	L:L:T211	9.88	No	No	0	0	0
286	L:L:V201	L:L:V210	3.21	Yes	No	7	0	0
287	L:L:G205	L:L:H203	4.77	No	Yes	7	0	0
288	L:L:H203	L:L:L206	3.86	Yes	No	7	0	0
289	L:L:G205	L:L:Q204	3.29	No	No	7	0	0
290	L:L:L206	L:L:V210	2.98	No	No	7	0	0
291	L:L:P209	L:L:S208	3.56	No	No	0	0	0
292	L:L:C219	M:M:C140	7.28	No	No	19	0	0
293	M:M:Q1	M:M:V2	2.87	No	No	0	0	0
294	M:M:Q1	M:M:Q3	3.84	No	No	0	0	0
295	M:M:G26	M:M:V2	1.84	No	No	0	0	0
296	M:M:V2	M:M:Y27	3.79	No	Yes	0	0	0
297	M:M:C22	M:M:L4	4.76	Yes	Yes	1	0	0
298	M:M:A24	M:M:L4	3.15	No	Yes	1	0	0
299	M:M:L4	M:M:Y27	3.52	Yes	Yes	1	0	0
300	M:M:L4	M:M:V115	7.45	Yes	No	0	0	0
301	M:M:G117	M:M:L4	1.71	No	Yes	0	0	0
302	M:M:C22	M:M:Q6	3.05	Yes	Yes	1	0	0
303	M:M:Q6	M:M:W36	2.19	Yes	Yes	1	0	0
304	M:M:C96	M:M:Q6	6.1	No	Yes	1	0	0
305	M:M:G119	M:M:Q6	4.93	No	Yes	0	0	0
306	M:M:Q6	M:M:T120	7.09	Yes	No	0	0	0
307	M:M:G8	M:M:S7	1.86	No	No	0	0	0
308	M:M:S21	M:M:S7	4.89	No	No	0	0	0
309	M:M:E10	M:M:K12	6.75	No	No	1	0	0
310	M:M:E10	M:M:V18	5.7	No	Yes	1	0	0
311	M:M:T123	M:M:V11	3.17	No	No	0	0	0
312	M:M:P160	M:M:V11	3.53	Yes	No	0	0	0
313	M:M:K12	M:M:V18	6.07	No	Yes	1	0	0
314	M:M:K13	M:M:P14	3.35	No	No	0	0	0
315	M:M:P14	M:M:V124	3.53	No	No	0	0	0
316	M:M:P14	M:M:S126	3.56	No	No	0	0	0
317	M:M:D82	M:M:S17	5.89	No	No	0	0	0
318	M:M:R84	M:M:S17	2.64	No	No	0	0	0
319	M:M:L83	M:M:V18	2.98	Yes	Yes	1	0	0
320	M:M:L86	M:M:V18	4.47	Yes	Yes	1	0	0
321	M:M:K19	M:M:Y80	9.55	No	No	0	0	0
322	M:M:D82	M:M:K19	12.44	No	No	0	0	0
323	M:M:V20	M:M:W36	7.36	No	Yes	0	0	0
324	M:M:C22	M:M:W36	2.61	Yes	Yes	1	0	0
325	M:M:C22	M:M:C96	7.28	Yes	No	1	0	0
326	M:M:K23	M:M:T78	6.01	No	Yes	0	0	0
327	M:M:A24	M:M:Y27	4	No	Yes	1	0	0
328	M:M:A24	M:M:F29	2.77	No	Yes	1	0	0
329	M:M:G26	M:M:S25	3.71	No	No	0	0	0
330	M:M:F29	M:M:Y27	4.13	Yes	Yes	1	0	0
331	M:M:Y27	M:M:Y32	1.99	Yes	Yes	1	0	0
332	M:M:R98	M:M:Y27	7.2	Yes	Yes	1	0	0
333	M:M:F29	M:M:I34	3.77	Yes	No	1	0	0
334	M:M:F29	M:M:T53	7.78	Yes	Yes	1	0	0
335	M:M:F29	M:M:S77	3.96	Yes	No	0	0	0
336	M:M:R74	M:M:T30	2.59	No	No	0	0	0
337	M:M:S31	M:M:Y32	6.36	Yes	Yes	1	0	0
338	M:M:S31	R:R:S178	3.26	Yes	Yes	1	0	1
339	M:M:S31	R:R:F189	3.96	Yes	Yes	1	0	3
340	M:M:R98	M:M:Y32	19.55	Yes	Yes	1	0	0
341	M:M:I101	M:M:Y32	3.63	Yes	Yes	1	0	0
342	M:M:Y32	R:R:S178	3.82	Yes	Yes	1	0	1
343	M:M:Y32	R:R:A180	2.67	Yes	No	0	0	1
344	M:M:G33	M:M:T53	1.82	No	Yes	0	0	0
345	M:M:I34	M:M:W36	2.35	No	Yes	1	0	0
346	M:M:I34	M:M:T53	3.04	No	Yes	1	0	0
347	M:M:S35	M:M:W47	4.94	No	Yes	0	0	0
348	M:M:H99	M:M:S35	4.18	Yes	No	0	0	0
349	M:M:M70	M:M:W36	5.82	Yes	Yes	1	0	0
350	M:M:M81	M:M:W36	19.78	Yes	Yes	1	0	0
351	M:M:C96	M:M:W36	10.45	No	Yes	1	0	0
352	M:M:V37	M:M:W116	2.45	No	Yes	0	0	0
353	M:M:E46	M:M:R38	16.28	No	Yes	1	0	0
354	M:M:M48	M:M:R38	7.44	No	Yes	1	0	0
355	M:M:K63	M:M:R38	3.71	No	Yes	1	0	0
356	M:M:R38	M:M:Y94	7.2	Yes	Yes	1	0	0
357	M:M:I45	M:M:Q39	9.61	No	Yes	1	0	0
358	M:M:Q39	M:M:Y95	4.51	Yes	Yes	1	0	0
359	M:M:A40	M:M:P41	1.87	No	No	0	0	0
360	M:M:A40	M:M:Q43	3.03	No	No	0	0	0
361	M:M:A40	M:M:A92	1.79	No	No	0	0	0
362	M:M:G44	M:M:Q43	4.93	No	No	0	0	0
363	M:M:E46	M:M:Q43	5.1	No	No	0	0	0
364	M:M:E46	M:M:K63	4.05	No	No	1	0	0
365	M:M:G49	M:M:W47	7.04	No	Yes	0	0	0
366	M:M:A61	M:M:W47	2.59	No	Yes	0	0	0
367	M:M:M48	M:M:Y94	4.79	No	Yes	1	0	0
368	M:M:G49	M:M:M70	1.75	No	Yes	0	0	0
369	M:M:S52	M:M:W50	3.71	Yes	Yes	1	0	0
370	M:M:H99	M:M:W50	9.52	Yes	Yes	1	0	0
371	M:M:W50	M:M:Y107	2.89	Yes	Yes	1	0	0
372	M:M:W50	R:R:P27	5.4	Yes	Yes	1	0	5
373	M:M:W50	R:R:F29	7.02	Yes	Yes	1	0	4
374	M:M:I51	M:M:R58	2.51	No	No	0	0	0
375	M:M:I51	M:M:M70	2.92	No	Yes	0	0	0
376	M:M:I51	M:M:T72	6.08	No	No	0	0	0
377	M:M:S52	M:M:Y54	2.54	Yes	No	1	0	0
378	M:M:N55	M:M:S52	2.98	Yes	Yes	1	0	0
379	M:M:G56	M:M:S52	1.86	No	Yes	0	0	0
380	M:M:S52	M:M:Y107	3.82	Yes	Yes	1	0	0
381	M:M:T53	M:M:T72	3.14	Yes	No	0	0	0
382	M:M:N55	M:M:Y54	6.98	Yes	No	1	0	0
383	M:M:Y54	R:R:D193	6.9	No	No	1	0	1
384	M:M:N55	M:M:N57	10.9	Yes	No	0	0	0
385	M:M:N55	R:R:D193	14.81	Yes	No	1	0	1
386	M:M:N57	M:M:Y107	3.49	No	Yes	0	0	0
387	M:M:R58	M:M:Y60	13.38	No	Yes	0	0	0
388	M:M:R58	R:R:M24	7.44	No	No	0	0	2
389	M:M:N59	R:R:E26	3.94	No	No	1	0	2
390	M:M:N59	R:R:P27	8.15	No	Yes	1	0	5
391	M:M:Q65	M:M:Y60	4.51	No	Yes	0	0	0
392	M:M:V68	M:M:Y60	6.31	Yes	Yes	0	0	0
393	M:M:M70	M:M:Y60	11.97	Yes	Yes	0	0	0
394	M:M:Q62	M:M:Q65	3.84	No	No	0	0	0
395	M:M:R67	M:M:V64	2.62	Yes	No	0	0	0
396	M:M:V64	M:M:V68	6.41	No	Yes	0	0	0
397	M:M:L83	M:M:R67	3.64	Yes	Yes	0	0	0
398	M:M:R67	M:M:S85	5.27	Yes	No	0	0	0
399	M:M:R67	M:M:R87	10.66	Yes	No	0	0	0
400	M:M:D90	M:M:R67	4.76	No	Yes	0	0	0
401	M:M:M81	M:M:V68	3.04	Yes	Yes	0	0	0
402	M:M:L83	M:M:V68	4.47	Yes	Yes	0	0	0
403	M:M:D82	M:M:T69	4.34	No	No	0	0	0
404	M:M:R84	M:M:T69	3.88	No	No	0	0	0
405	M:M:M70	M:M:M81	4.33	Yes	Yes	1	0	0
406	M:M:T71	M:M:Y80	2.5	No	No	0	0	0
407	M:M:D73	M:M:S75	2.94	No	No	0	0	0
408	M:M:D73	M:M:T76	11.56	No	No	0	0	0
409	M:M:T76	M:M:T78	4.71	No	Yes	0	0	0
410	M:M:T78	M:M:Y80	8.74	Yes	No	0	0	0
411	M:M:M81	M:M:Y94	3.59	Yes	Yes	1	0	0
412	M:M:L83	M:M:L86	2.77	Yes	Yes	1	0	0
413	M:M:L83	M:M:Y94	3.52	Yes	Yes	1	0	0
414	M:M:D90	M:M:L86	8.14	No	Yes	0	0	0
415	M:M:L86	M:M:V124	4.47	Yes	No	0	0	0
416	M:M:D90	M:M:Y94	3.45	No	Yes	0	0	0
417	M:M:T123	M:M:T91	7.85	No	No	0	0	0
418	M:M:V93	M:M:Y95	7.57	No	Yes	0	0	0
419	M:M:T121	M:M:V93	3.17	No	No	0	0	0
420	M:M:V122	M:M:Y94	6.31	No	Yes	0	0	0
421	M:M:W116	M:M:Y95	7.72	Yes	Yes	1	0	0
422	M:M:G119	M:M:Y95	4.35	No	Yes	0	0	0
423	M:M:A97	M:M:M113	3.22	No	Yes	1	0	0
424	M:M:A97	M:M:W116	7.78	No	Yes	1	0	0
425	M:M:D114	M:M:R98	2.38	No	Yes	0	0	0
426	M:M:R98	M:M:V115	2.62	Yes	No	0	0	0
427	M:M:H99	M:M:M113	6.57	Yes	Yes	1	0	0
428	M:M:I101	M:M:Y108	3.63	Yes	Yes	1	0	0
429	M:M:I101	M:M:Y111	4.84	Yes	Yes	1	0	0
430	M:M:I101	R:R:I185	4.42	Yes	Yes	1	0	3
431	M:M:G103	M:M:T102	1.82	No	No	0	0	0
432	M:M:T102	M:M:Y107	4.99	No	Yes	0	0	0
433	M:M:G103	R:R:F189	3.01	No	Yes	0	0	3
434	M:M:A104	R:R:D187	4.63	No	Yes	0	0	3
435	M:M:A104	R:R:Y190	2.67	No	Yes	0	0	4
436	M:M:R105	R:R:R30	2.13	No	No	0	0	5
437	M:M:R105	R:R:D187	3.57	No	Yes	0	0	3
438	M:M:N106	M:M:Y108	13.96	No	Yes	0	0	0
439	M:M:N106	R:R:I185	4.25	No	Yes	0	0	3
440	M:M:N106	R:R:D187	6.73	No	Yes	0	0	3
441	M:M:Y107	R:R:F29	4.13	Yes	Yes	1	0	4
442	M:M:H110	M:M:Y108	7.62	No	Yes	1	0	0
443	M:M:Y108	M:M:Y111	1.99	Yes	Yes	1	0	0
444	M:M:Y108	R:R:R30	3.09	Yes	No	0	0	5
445	M:M:Y108	R:R:E32	3.37	Yes	No	0	0	4
446	M:M:Y109	R:R:F29	20.63	No	Yes	1	0	4
447	M:M:H110	M:M:Y111	17.42	No	Yes	1	0	0
448	M:M:Y111	R:R:A180	5.34	Yes	No	0	0	1
449	M:M:Y111	R:R:D181	6.9	Yes	No	1	0	2
450	M:M:Y111	R:R:R183	4.12	Yes	Yes	0	0	3
451	M:M:G112	R:R:D181	3.35	No	No	1	0	2
452	M:M:M113	M:M:W116	6.98	Yes	Yes	1	0	0
453	M:M:A127	M:M:S125	1.71	No	No	0	0	0
454	M:M:F159	M:M:S125	6.61	No	No	0	0	0
455	M:M:S128	M:M:T129	3.2	No	Yes	0	0	0
456	M:M:K130	M:M:S128	4.59	No	No	0	0	0
457	M:M:P160	M:M:T129	3.5	Yes	Yes	9	0	0
458	M:M:P215	M:M:T129	3.5	Yes	Yes	9	0	0
459	M:M:S216	M:M:T129	4.8	No	Yes	0	0	0
460	M:M:G131	M:M:K130	1.74	No	No	0	0	0
461	M:M:K130	M:M:L188	2.82	No	Yes	0	0	0
462	M:M:G131	M:M:P132	4.06	No	Yes	0	0	0
463	M:M:P132	M:M:V155	1.77	Yes	No	9	0	0
464	M:M:P132	M:M:Y158	2.78	Yes	Yes	9	0	0
465	M:M:H213	M:M:P132	13.73	Yes	Yes	9	0	0
466	M:M:P132	M:M:T218	3.5	Yes	No	9	0	0
467	M:M:F135	M:M:S133	9.25	Yes	No	0	0	0
468	M:M:C153	M:M:V134	3.42	Yes	Yes	9	0	0
469	M:M:V134	M:M:V155	4.81	Yes	No	9	0	0
470	M:M:V134	M:M:V211	4.81	Yes	No	9	0	0
471	M:M:V134	M:M:V220	6.41	Yes	No	9	0	0
472	M:M:K222	M:M:V134	3.04	No	Yes	9	0	0
473	M:M:F135	M:M:L154	2.44	Yes	No	0	0	0
474	M:M:K222	M:M:P136	5.02	No	No	0	0	0
475	M:M:P136	M:M:V224	5.3	No	No	0	0	0
476	M:M:G152	M:M:L137	1.71	No	No	0	0	0
477	M:M:A138	M:M:P139	1.87	No	Yes	0	0	0
478	M:M:L151	M:M:P139	3.28	Yes	Yes	0	0	0
479	M:M:P139	M:M:S226	1.78	Yes	No	0	0	0
480	M:M:P198	M:M:T148	1.75	No	No	0	0	0
481	M:M:A149	M:M:S199	1.71	No	No	0	0	0
482	M:M:A150	M:M:T196	5.03	No	No	0	0	0
483	M:M:G152	M:M:L151	1.71	No	Yes	0	0	0
484	M:M:L151	M:M:Y207	4.69	Yes	Yes	0	0	0
485	M:M:L151	M:M:V224	7.45	Yes	No	0	0	0
486	M:M:G152	M:M:W167	2.81	No	Yes	0	0	0
487	M:M:C153	M:M:W167	3.92	Yes	Yes	9	0	0
488	M:M:C153	M:M:C209	7.28	Yes	No	9	0	0
489	M:M:C153	M:M:V224	1.71	Yes	No	0	0	0
490	M:M:L154	M:M:S192	4.5	No	No	0	0	0
491	M:M:V155	M:M:Y158	5.05	No	Yes	9	0	0
492	M:M:K156	M:M:Q184	9.49	No	No	0	0	0
493	M:M:D157	M:M:L188	6.79	No	Yes	0	0	0
494	M:M:V163	M:M:Y158	7.57	No	Yes	9	0	0
495	M:M:Y158	M:M:Y189	8.94	Yes	No	0	0	0
496	M:M:L191	M:M:Y158	4.69	No	Yes	0	0	0
497	M:M:H213	M:M:Y158	2.18	Yes	Yes	9	0	0
498	M:M:F159	M:M:P160	17.34	No	Yes	0	0	0
499	M:M:F159	M:M:L188	4.87	No	Yes	0	0	0
500	M:M:H213	M:M:P160	3.05	Yes	Yes	9	0	0
501	M:M:P160	M:M:P215	5.84	Yes	Yes	9	0	0
502	M:M:E161	M:M:P162	4.72	No	No	0	0	0
503	M:M:E161	M:M:Y189	4.49	No	No	0	0	0
504	M:M:H213	M:M:V163	5.54	Yes	No	9	0	0
505	M:M:D212	M:M:T164	4.34	No	No	0	0	0
506	M:M:S193	M:M:V165	4.85	No	No	0	0	0
507	M:M:C209	M:M:V165	3.42	No	No	0	0	0
508	M:M:V165	M:M:V211	4.81	No	No	0	0	0
509	M:M:G170	M:M:S166	1.86	No	No	0	0	0
510	M:M:V195	M:M:W167	13.48	No	Yes	9	0	0
511	M:M:W167	M:M:Y207	2.89	Yes	Yes	0	0	0
512	M:M:C209	M:M:W167	7.84	No	Yes	9	0	0
513	M:M:N168	M:M:Y207	2.33	No	Yes	0	0	0
514	M:M:N168	M:M:T208	7.31	No	No	0	0	0
515	M:M:L172	M:M:S174	3	Yes	No	0	0	0
516	M:M:V176	M:M:V195	3.21	No	No	9	0	0
517	M:M:S193	M:M:T178	7.99	No	No	0	0	0
518	M:M:A181	M:M:L191	3.15	No	No	0	0	0
519	M:M:L183	M:M:Y189	3.52	No	No	0	0	0
520	M:M:Q184	M:M:S190	8.66	No	No	0	0	0
521	M:M:G187	M:M:S186	1.86	No	No	0	0	0
522	M:M:G187	M:M:L188	1.71	No	Yes	0	0	0
523	M:M:P198	M:M:V197	5.3	No	No	0	0	0
524	M:M:V197	M:M:Y207	10.09	No	Yes	0	0	0
525	M:M:L202	M:M:S199	6.01	No	No	0	0	0
526	M:M:S201	M:M:T204	6.4	No	No	0	0	0
527	M:M:G203	M:M:L202	1.71	No	No	0	0	0
528	M:M:K205	M:M:T204	4.5	No	No	0	0	0
529	M:M:K205	M:M:Y207	4.78	No	Yes	0	0	0
530	M:M:R223	M:M:T206	3.88	No	No	21	0	0
531	M:M:E225	M:M:T206	2.82	No	No	21	0	0
532	M:M:D221	M:M:N210	14.81	No	No	0	0	0
533	M:M:V211	M:M:V220	3.21	No	No	9	0	0
534	M:M:D212	M:M:K219	2.77	No	No	0	0	0
535	M:M:H213	M:M:P215	13.73	Yes	Yes	9	0	0
536	M:M:H213	M:M:S216	4.18	Yes	No	0	0	0
537	M:M:H213	M:M:T218	2.74	Yes	No	9	0	0
538	M:M:D221	M:M:K219	6.91	No	No	0	0	0
539	M:M:K222	M:M:V220	3.04	No	No	9	0	0
540	M:M:E225	M:M:R223	8.14	No	No	21	0	0
541	R:R:E26	R:R:K25	2.7	No	No	0	2	4
542	R:R:E26	R:R:P27	3.14	No	Yes	1	2	5
543	R:R:F29	R:R:P27	5.78	Yes	Yes	1	4	5
544	R:R:C274	R:R:C28	5.46	No	No	0	5	9
545	R:R:C28	R:R:E277	4.56	No	No	0	9	2
546	R:R:H281	R:R:R30	12.41	No	No	0	4	5
547	R:R:E31	R:R:N278	7.89	No	No	0	5	3
548	R:R:E31	R:R:K282	2.7	No	No	0	5	2
549	R:R:E32	R:R:N37	2.63	No	No	0	4	3
550	R:R:N33	R:R:N35	4.09	No	No	0	6	3
551	R:R:F36	R:R:N33	3.62	No	No	0	4	6
552	R:R:K282	R:R:N33	2.8	No	No	0	2	6
553	R:R:I39	R:R:N35	2.83	No	No	0	5	3
554	R:R:F36	R:R:S285	2.64	No	No	0	4	5
555	R:R:F36	R:R:I286	7.54	No	No	0	4	6
556	R:R:F40	R:R:I39	6.28	No	No	0	5	5
557	R:R:P42	R:R:V99	3.53	No	No	0	5	4
558	R:R:I44	R:R:I48	2.94	No	No	0	5	7
559	R:R:A95	R:R:Y45	2.67	No	No	0	7	7
560	R:R:F292	R:R:Y45	7.22	Yes	No	0	7	7
561	R:R:I48	R:R:L91	2.85	No	No	0	7	8
562	R:R:F293	R:R:I48	15.07	No	No	0	5	7
563	R:R:F49	R:R:L50	2.44	Yes	No	0	6	5
564	R:R:F49	R:R:I53	2.51	Yes	No	0	6	5
565	R:R:F49	R:R:V88	2.62	Yes	No	0	6	6
566	R:R:F49	R:R:L91	3.65	Yes	No	0	6	8
567	R:R:F49	R:R:P92	7.22	Yes	No	0	6	9
568	R:R:G52	R:R:T51	1.82	No	No	5	8	5
569	R:R:C296	R:R:T51	5.07	No	No	5	7	5
570	R:R:G52	R:R:V88	1.84	No	No	0	8	6
571	R:R:C296	R:R:G52	1.96	No	No	5	7	8
572	R:R:G55	R:R:V54	1.84	No	No	0	8	4
573	R:R:D84	R:R:N56	9.42	Yes	No	0	9	9
574	R:R:N56	R:R:P299	6.52	No	No	0	9	9
575	R:R:F304	R:R:L58	2.44	No	No	0	6	5
576	R:R:S81	R:R:V59	6.46	No	No	0	9	8
577	R:R:P299	R:R:V59	1.77	No	No	0	9	8
578	R:R:F304	R:R:V59	2.62	No	No	0	6	8
579	R:R:I60	R:R:S81	4.64	No	No	0	7	9
580	R:R:L61	R:R:Y65	3.52	No	No	0	4	5
581	R:R:F309	R:R:V62	7.87	Yes	No	0	8	7
582	R:R:A313	R:R:V62	3.39	No	No	0	5	7
583	R:R:G64	R:R:M63	1.75	No	Yes	0	2	6
584	R:R:D74	R:R:M63	5.54	Yes	Yes	17	8	6
585	R:R:M63	R:R:R77	4.96	Yes	No	17	6	8
586	R:R:F309	R:R:M63	2.49	Yes	Yes	17	8	6
587	R:R:D74	R:R:Q66	6.53	Yes	No	0	8	4
588	R:R:Q66	R:R:S312	4.33	No	No	0	4	6
589	B:B:D312	R:R:K67	5.53	No	No	0	5	6
590	B:B:F335	R:R:K67	4.96	No	No	0	4	6
591	R:R:K75	R:R:R70	2.48	No	No	3	6	6
592	R:R:R70	W:W:?1	4.88	No	Yes	3	6	0
593	R:R:D74	R:R:S71	5.89	Yes	No	0	8	7
594	A:A:D350	R:R:S71	5.89	No	No	0	4	7
595	R:R:D133	R:R:M72	2.77	No	No	3	8	6
596	R:R:M72	R:R:R148	8.69	No	Yes	3	6	6
597	R:R:K149	R:R:M72	2.88	No	No	0	6	6
598	R:R:D74	R:R:R77	4.76	Yes	No	17	8	8
599	R:R:E153	R:R:K75	14.85	No	No	0	7	6
600	R:R:K75	W:W:?1	4.25	No	Yes	3	6	0
601	R:R:F129	R:R:Y76	3.09	Yes	Yes	3	5	7
602	R:R:I130	R:R:Y76	4.84	Yes	Yes	3	8	7
603	R:R:D133	R:R:Y76	5.75	No	Yes	3	8	7
604	R:R:A152	R:R:Y76	5.34	No	Yes	0	3	7
605	R:R:V156	R:R:Y76	5.05	Yes	Yes	3	5	7
606	R:R:F309	R:R:R77	6.41	Yes	No	17	8	8
607	R:R:L78	W:W:?1	9.73	No	Yes	0	5	0
608	R:R:H79	R:R:I126	2.65	Yes	Yes	0	9	7
609	R:R:H79	R:R:V156	4.15	Yes	Yes	3	9	5
610	R:R:H79	R:R:W161	6.35	Yes	Yes	3	9	9
611	R:R:H79	W:W:?1	18.07	Yes	Yes	3	9	0
612	R:R:D84	R:R:L80	5.43	Yes	Yes	5	9	9
613	R:R:I126	R:R:L80	5.71	Yes	Yes	0	7	9
614	R:R:L127	R:R:L80	2.77	No	Yes	0	8	9
615	R:R:L80	R:R:N298	6.87	Yes	No	5	9	9
616	R:R:V82	W:W:?1	5.98	No	Yes	0	5	0
617	R:R:A83	R:R:S122	3.42	No	No	0	8	7
618	R:R:A83	R:R:S123	1.71	No	No	0	8	9
619	R:R:D84	R:R:S123	4.42	Yes	No	5	9	9
620	R:R:D84	R:R:H294	2.52	Yes	Yes	5	9	9
621	R:R:C295	R:R:D84	3.11	Yes	Yes	5	9	9
622	R:R:D84	R:R:N298	6.73	Yes	No	5	9	9
623	R:R:F87	R:R:Y116	4.13	Yes	No	5	7	6
624	R:R:F87	R:R:S119	9.25	Yes	No	0	7	8
625	R:R:F87	R:R:L120	2.44	Yes	Yes	5	7	7
626	R:R:F292	R:R:F87	7.5	Yes	Yes	5	7	7
627	R:R:F87	R:R:H294	9.05	Yes	Yes	5	7	9
628	R:R:C295	R:R:V88	3.42	Yes	No	0	9	6
629	R:R:T90	R:R:W94	6.06	No	Yes	0	6	7
630	R:R:I115	R:R:T90	3.04	No	No	0	5	6
631	R:R:F292	R:R:L91	2.44	Yes	No	0	7	8
632	R:R:F104	R:R:F93	8.57	Yes	No	0	7	6
633	R:R:F93	R:R:V112	5.24	No	No	0	6	5
634	R:R:D97	R:R:W94	2.23	No	Yes	0	5	7
635	R:R:V112	R:R:W94	4.9	No	Yes	0	5	7
636	R:R:H113	R:R:W94	6.35	Yes	Yes	0	6	7
637	R:R:F104	R:R:V96	3.93	Yes	No	0	7	5
638	R:R:D97	R:R:W102	4.47	No	Yes	0	5	9
639	R:R:D97	R:R:R183	2.38	No	Yes	0	5	3
640	R:R:A100	R:R:N101	3.13	No	No	22	5	4
641	R:R:A100	R:R:Y103	2.67	No	No	22	5	3
642	R:R:N101	R:R:Y103	18.61	No	No	22	4	3
643	R:R:N101	R:R:R183	6.03	No	Yes	0	4	3
644	R:R:F104	R:R:W102	16.04	Yes	Yes	0	7	9
645	R:R:C109	R:R:W102	3.92	No	Yes	5	9	9
646	R:R:V112	R:R:W102	2.45	No	Yes	0	5	9
647	R:R:V177	R:R:W102	2.45	Yes	Yes	5	4	9
648	R:R:C186	R:R:W102	16.98	No	Yes	5	9	9
649	R:R:F104	R:R:L108	4.87	Yes	No	0	7	5
650	R:R:N106	R:R:N176	4.09	No	No	0	3	4
651	R:R:N106	R:R:V177	5.91	No	Yes	0	3	4
652	R:R:C109	R:R:V177	3.42	No	Yes	5	9	4
653	R:R:C109	R:R:C186	7.28	No	No	5	9	9
654	R:R:D171	R:R:H113	10.08	No	Yes	5	4	6
655	R:R:C186	R:R:H113	2.95	No	Yes	5	9	6
656	R:R:H113	R:R:R188	5.64	Yes	Yes	5	6	5
657	R:R:T168	R:R:V114	3.17	No	No	0	6	5
658	R:R:F172	R:R:V114	7.87	No	No	0	4	5
659	R:R:L120	R:R:Y116	3.52	Yes	No	5	7	6
660	R:R:F292	R:R:Y116	3.09	Yes	No	5	7	6
661	R:R:T117	R:R:Y121	2.5	No	Yes	0	5	7
662	R:R:T117	R:R:T168	3.14	No	No	0	5	6
663	R:R:D171	R:R:T117	8.67	No	No	0	4	5
664	R:R:H203	R:R:L120	3.86	Yes	Yes	5	4	7
665	R:R:L120	R:R:W252	3.42	Yes	Yes	5	7	9
666	R:R:L167	R:R:Y121	2.34	No	Yes	5	5	7
667	R:R:Q202	R:R:Y121	6.76	Yes	Yes	5	3	7
668	R:R:H203	R:R:Y121	7.62	Yes	Yes	5	4	7
669	R:R:V206	R:R:Y121	5.05	No	Yes	5	4	7
670	R:R:S122	R:R:W161	7.41	No	Yes	0	7	9
671	R:R:H294	R:R:S123	4.18	Yes	No	5	9	9
672	R:R:P211	R:R:V124	3.53	Yes	No	0	9	7
673	R:R:F248	R:R:V124	2.62	Yes	No	0	9	7
674	R:R:I126	R:R:I130	2.94	Yes	Yes	0	7	8
675	R:R:I126	R:R:V160	4.61	Yes	No	0	7	7
676	R:R:F248	R:R:L127	2.44	Yes	No	0	9	8
677	R:R:L127	R:R:Y302	4.69	No	Yes	0	8	9
678	R:R:A128	R:R:P211	1.87	No	Yes	0	7	9
679	R:R:A128	R:R:V214	3.39	No	No	0	7	6
680	R:R:F129	R:R:V156	3.93	Yes	Yes	3	5	5
681	R:R:F129	R:R:G159	3.01	Yes	No	0	5	3
682	R:R:F129	R:R:V160	2.62	Yes	No	0	5	7
683	R:R:I130	R:R:R134	6.26	Yes	Yes	3	8	9
684	R:R:I130	R:R:Y302	4.84	Yes	Yes	3	8	9
685	R:R:C218	R:R:S131	5.16	Yes	No	0	6	9
686	R:R:D133	R:R:R148	14.29	No	Yes	3	8	6
687	R:R:R134	R:R:Y219	7.2	Yes	Yes	0	9	8
688	R:R:R134	R:R:Y302	6.17	Yes	Yes	3	9	9
689	A:A:C351	R:R:R134	2.79	No	Yes	0	4	9
690	A:A:L353	R:R:R134	7.29	Yes	Yes	3	7	9
691	R:R:L136	R:R:Y135	2.34	Yes	Yes	0	5	8
692	R:R:V139	R:R:Y135	8.83	No	Yes	23	7	8
693	R:R:H140	R:R:Y135	7.62	No	Yes	23	6	8
694	R:R:C218	R:R:Y135	4.03	Yes	Yes	0	6	8
695	R:R:I221	R:R:Y135	6.04	No	Yes	0	4	8
696	R:R:L136	R:R:S144	3	Yes	No	0	5	5
697	R:R:L136	R:R:R148	3.64	Yes	Yes	0	5	6
698	R:R:A137	R:R:R148	6.91	No	Yes	0	8	6
699	A:A:C351	R:R:A137	1.81	No	No	0	4	8
700	R:R:I138	R:R:I222	2.94	No	No	0	8	8
701	A:A:L348	R:R:I138	4.28	Yes	No	0	9	8
702	R:R:H140	R:R:V139	6.92	No	No	23	6	7
703	R:R:K225	R:R:V139	4.55	No	No	0	4	7
704	R:R:H140	R:R:S144	2.79	No	No	0	6	5
705	R:R:N143	R:R:T142	4.39	No	No	0	5	5
706	A:A:T340	R:R:T142	3.14	No	No	0	6	5
707	A:A:R32	R:R:Q145	2.34	No	No	0	4	5
708	R:R:P147	R:R:R146	5.76	No	No	0	4	5
709	R:R:L150	R:R:R146	2.43	No	No	0	4	5
710	R:R:E153	R:R:K149	2.7	No	No	0	7	6
711	A:A:E28	R:R:K149	4.05	No	No	0	4	6
712	R:R:L151	R:R:V155	4.47	No	No	0	4	2
713	R:R:V156	R:R:Y157	7.57	Yes	No	0	5	7
714	R:R:Y157	W:W:?1	9.42	No	Yes	0	7	0
715	R:R:G159	R:R:V158	3.68	No	No	0	3	4
716	R:R:G159	R:R:P163	4.06	No	No	0	3	4
717	R:R:V160	R:R:W161	8.58	No	Yes	0	7	9
718	R:R:W161	W:W:?1	9.15	Yes	Yes	3	9	0
719	R:R:I162	R:R:P163	3.39	No	No	0	4	4
720	R:R:I162	R:R:L166	2.85	No	No	0	4	4
721	R:R:L165	W:W:?1	4.17	No	Yes	0	3	0
722	R:R:L167	R:R:Q202	7.99	No	Yes	5	5	3
723	R:R:I169	R:R:P170	3.39	No	No	0	3	8
724	R:R:I169	R:R:I173	2.94	No	No	0	3	3
725	R:R:F174	R:R:P170	2.89	Yes	No	5	4	8
726	R:R:F199	R:R:P170	10.11	Yes	No	5	5	8
727	R:R:D171	R:R:R188	11.91	No	Yes	5	4	5
728	R:R:F174	R:R:I173	12.56	Yes	No	0	4	3
729	R:R:F174	R:R:Y190	9.28	Yes	Yes	5	4	4
730	R:R:F174	R:R:P191	2.89	Yes	No	0	4	5
731	R:R:F174	R:R:F199	3.22	Yes	Yes	5	4	5
732	R:R:F189	R:R:N176	3.62	Yes	No	0	3	4
733	R:R:I185	R:R:S178	3.1	Yes	Yes	1	3	1
734	R:R:F189	R:R:S178	6.61	Yes	Yes	1	3	1
735	R:R:E179	R:R:Y184	16.83	No	No	0	2	5
736	R:R:I185	R:R:R183	2.51	Yes	Yes	0	3	3
737	R:R:F189	R:R:I185	3.77	Yes	Yes	1	3	3
738	R:R:D187	R:R:R188	2.38	Yes	Yes	0	3	5
739	R:R:R188	R:R:Y190	13.38	Yes	Yes	5	5	4
740	R:R:F199	R:R:R188	2.14	Yes	Yes	5	5	5
741	R:R:W195	R:R:Y190	3.86	Yes	Yes	5	5	4
742	R:R:V196	R:R:Y190	6.31	No	Yes	0	4	4
743	R:R:F199	R:R:Y190	12.38	Yes	Yes	5	5	4
744	R:R:P191	R:R:W195	4.05	No	Yes	0	5	5
745	R:R:L194	R:R:N192	6.87	No	No	0	2	1
746	R:R:N192	R:R:W195	5.65	No	Yes	0	1	5
747	R:R:L194	R:R:V198	2.98	No	No	0	2	3
748	R:R:F199	R:R:W195	3.01	Yes	Yes	5	5	5
749	R:R:Q200	R:R:V196	2.87	Yes	No	0	5	4
750	R:R:L266	R:R:V196	2.98	No	No	0	3	4
751	R:R:L266	R:R:V197	2.98	No	No	0	3	3
752	R:R:L267	R:R:V197	4.47	No	No	0	1	3
753	R:R:F199	R:R:Q202	2.34	Yes	Yes	5	5	3
754	R:R:I259	R:R:Q200	6.86	No	Yes	0	5	5
755	R:R:D262	R:R:Q200	3.92	Yes	Yes	0	5	5
756	R:R:Q200	R:R:S263	8.66	Yes	No	0	5	5
757	R:R:F201	R:R:S263	5.28	No	No	0	4	5
758	R:R:Q202	R:R:V206	2.87	Yes	No	5	3	4
759	R:R:H203	R:R:Y255	4.36	Yes	Yes	5	4	7
760	R:R:H203	R:R:Y256	9.8	Yes	Yes	5	4	8
761	R:R:I204	R:R:Y256	4.84	No	Yes	0	5	8
762	R:R:I209	R:R:M205	4.37	No	No	0	4	4
763	R:R:G207	R:R:Y256	2.9	No	Yes	0	5	8
764	R:R:F249	R:R:L208	2.44	Yes	No	0	4	8
765	R:R:L208	R:R:Y256	9.38	No	Yes	0	8	8
766	R:R:L210	R:R:P211	3.28	No	Yes	0	6	9
767	R:R:F249	R:R:G212	3.01	Yes	No	0	4	6
768	R:R:C218	R:R:V214	1.71	Yes	No	0	6	6
769	R:R:I215	R:R:Y219	2.42	No	Yes	0	7	8
770	R:R:F248	R:R:I215	7.54	Yes	No	0	9	7
771	R:R:C220	R:R:L216	3.17	No	No	0	3	4
772	R:R:F249	R:R:L216	3.65	Yes	No	0	4	4
773	R:R:C218	R:R:S217	1.72	Yes	No	0	6	3
774	R:R:I222	R:R:Y219	2.42	No	Yes	0	8	8
775	R:R:L244	R:R:Y219	4.69	No	Yes	0	7	8
776	R:R:I245	R:R:Y219	7.25	No	Yes	0	7	8
777	R:R:I222	R:R:L226	2.85	No	Yes	0	8	8
778	R:R:I223	R:R:L238	2.85	No	No	0	4	5
779	R:R:I223	R:R:T241	4.56	No	No	0	4	7
780	R:R:I223	R:R:V242	3.07	No	No	0	4	4
781	R:R:K234	R:R:L226	5.64	Yes	Yes	3	7	8
782	A:A:L348	R:R:L226	4.15	Yes	Yes	3	9	8
783	R:R:H228	R:R:S227	4.18	No	No	0	5	4
784	R:R:G231	R:R:S229	1.86	No	No	0	4	5
785	R:R:K234	R:R:S229	12.24	Yes	No	0	7	5
786	R:R:K230	R:R:R235	2.48	No	No	0	5	5
787	A:A:D315	R:R:H232	2.52	No	No	0	3	4
788	A:A:K345	R:R:Q233	4.07	Yes	No	0	5	5
789	A:A:F354	R:R:Q233	10.54	Yes	No	0	5	5
790	A:A:D341	R:R:K234	5.53	No	Yes	3	8	7
791	A:A:K345	R:R:K234	4.31	Yes	Yes	3	5	7
792	R:R:K239	R:R:R235	2.48	No	No	0	6	5
793	A:A:F354	R:R:K236	7.44	Yes	No	0	5	8
794	A:A:L353	R:R:T241	4.42	Yes	No	0	7	7
795	R:R:L244	R:R:L301	5.54	No	Yes	3	7	7
796	R:R:L244	R:R:Y302	2.34	No	Yes	3	7	9
797	R:R:F248	R:R:F249	9.65	Yes	Yes	0	9	4
798	R:R:F248	R:R:W252	3.01	Yes	Yes	0	9	9
799	R:R:W252	R:R:Y255	2.89	Yes	Yes	5	9	7
800	R:R:W252	R:R:Y256	7.72	Yes	Yes	5	9	8
801	R:R:A291	R:R:W252	2.59	No	Yes	5	8	9
802	R:R:H294	R:R:W252	11.64	Yes	Yes	5	9	9
803	R:R:I257	R:R:L253	2.85	No	No	0	6	5
804	R:R:P254	R:R:T287	3.5	No	Yes	0	9	6
805	R:R:Y255	R:R:Y256	4.96	Yes	Yes	5	7	8
806	R:R:I259	R:R:Y255	10.88	No	Yes	0	5	7
807	R:R:T287	R:R:Y255	2.5	Yes	Yes	0	6	7
808	R:R:E288	R:R:Y255	5.61	No	Yes	0	5	7
809	R:R:A291	R:R:Y255	2.67	No	Yes	5	8	7
810	R:R:I257	R:R:W283	2.35	No	No	0	6	6
811	R:R:G258	R:R:I261	3.53	No	No	0	4	5
812	R:R:G258	R:R:I284	3.53	No	No	0	4	4
813	R:R:I261	R:R:V280	3.07	No	No	0	5	5
814	R:R:I261	R:R:W283	3.52	No	No	0	5	6
815	R:R:D262	R:R:L266	4.07	Yes	No	0	5	3
816	R:R:D262	R:R:H281	10.08	Yes	No	0	5	4
817	R:R:D262	R:R:I284	4.2	Yes	No	0	5	4
818	R:R:F264	R:R:I269	8.79	No	No	0	4	1
819	R:R:F264	R:R:I270	3.77	No	No	0	4	5
820	R:R:E277	R:R:I265	6.83	No	No	0	2	3
821	R:R:F276	R:R:I270	2.51	No	No	0	1	5
822	R:R:F276	R:R:Q272	4.68	No	No	0	1	2
823	R:R:E275	R:R:T279	2.82	No	No	0	3	2
824	R:R:E277	R:R:H281	4.92	No	No	0	2	4
825	R:R:I284	R:R:V280	3.07	No	No	0	4	5
826	R:R:T287	R:R:W283	4.85	Yes	No	0	6	6
827	R:R:E288	R:R:F292	7	No	Yes	0	5	7
828	R:R:C295	R:R:H294	2.95	Yes	Yes	5	9	9
829	R:R:C295	R:R:C296	1.82	Yes	No	5	9	7
830	R:R:L301	R:R:Y302	2.34	Yes	Yes	3	7	9
831	R:R:A303	R:R:F309	6.93	No	Yes	0	7	8
832	R:R:F304	R:R:F309	6.43	No	Yes	0	6	8
833	R:R:H315	R:R:T311	2.74	No	No	0	4	4
834	A:A:D9	A:A:S6	7.36	No	No	0	4	7
835	A:A:S16	B:B:N88	5.96	No	No	0	7	7
836	A:A:M18	A:A:N22	4.21	No	No	0	4	4
837	A:A:I19	B:B:K89	2.91	No	Yes	0	9	9
838	A:A:D20	B:B:K89	8.3	No	Yes	0	6	9
839	A:A:L23	B:B:K78	4.23	No	Yes	0	6	8
840	A:A:L23	B:B:K89	2.82	No	Yes	0	6	9
841	A:A:D26	B:B:K78	5.53	No	Yes	0	5	8
842	A:A:A30	A:A:G27	1.95	No	No	0	3	5
843	A:A:G27	B:B:L55	1.71	No	No	0	5	6
844	A:A:E33	A:A:H195	12.31	No	No	0	6	4
845	A:A:E33	A:A:K197	5.4	No	No	0	6	6
846	A:A:L194	A:A:V34	4.47	No	Yes	3	4	5
847	A:A:F196	A:A:V34	5.24	Yes	Yes	3	7	5
848	A:A:T219	A:A:V34	4.76	No	Yes	0	7	5
849	A:A:V339	A:A:V34	3.21	No	Yes	3	8	5
850	A:A:F199	A:A:K35	7.44	Yes	No	2	5	9
851	A:A:K35	B:B:W99	4.64	No	Yes	2	9	9
852	A:A:L36	A:A:M198	2.83	No	Yes	0	7	7
853	A:A:L37	A:A:V201	2.98	No	Yes	2	9	9
854	A:A:F215	A:A:L37	7.31	Yes	No	2	9	9
855	A:A:I221	A:A:L37	2.85	No	No	2	8	9
856	A:A:I49	A:A:L38	4.28	Yes	No	3	7	8
857	A:A:L38	A:A:M198	9.9	No	Yes	3	8	7
858	A:A:I222	A:A:L38	5.71	No	No	3	7	8
859	A:A:G40	A:A:L39	1.71	No	No	0	9	9
860	A:A:F223	A:A:L39	2.44	Yes	No	0	9	9
861	A:A:I253	A:A:L39	4.28	No	No	0	8	9
862	A:A:G40	A:A:G45	2.11	No	No	0	9	9
863	A:A:A41	A:A:G42	1.95	No	No	0	7	8
864	A:A:A41	A:A:S246	3.42	No	No	0	7	9
865	A:A:A41	A:A:L249	4.73	No	No	0	7	9
866	A:A:G42	A:A:R242	3	No	No	0	8	9
867	A:A:K46	A:A:S44	13.77	No	No	18	9	9
868	A:A:S44	A:A:T202	3.2	No	No	18	9	9
869	A:A:C224	A:A:G45	3.92	No	No	0	7	9
870	A:A:D200	A:A:K46	6.91	No	No	18	9	9
871	A:A:K46	A:A:T202	4.5	No	No	18	9	9
872	A:A:C47	A:A:T48	5.07	No	No	0	9	9
873	A:A:K51	A:A:T48	3	No	No	0	9	9
874	A:A:N269	A:A:T48	8.77	No	No	0	9	9
875	A:A:I49	A:A:Q52	2.74	Yes	No	0	7	9
876	A:A:I49	A:A:M198	2.92	Yes	Yes	3	7	7
877	A:A:C224	A:A:I49	3.27	No	Yes	0	7	7
878	A:A:Q52	A:A:V332	2.87	No	No	0	9	7
879	A:A:F189	A:A:M53	2.49	Yes	No	0	9	8
880	A:A:G183	A:A:T182	3.64	No	No	2	9	7
881	A:A:T182	B:B:N119	5.85	No	Yes	2	7	9
882	A:A:T182	B:B:I120	3.04	No	Yes	0	7	6
883	A:A:A203	A:A:G183	1.95	No	No	0	9	9
884	A:A:G183	B:B:N119	3.39	No	Yes	2	9	9
885	A:A:F199	A:A:I184	2.51	Yes	Yes	2	5	9
886	A:A:I184	A:A:V201	3.07	Yes	Yes	2	9	9
887	A:A:F215	A:A:I184	2.51	Yes	Yes	2	9	9
888	A:A:I184	B:B:W99	3.52	Yes	Yes	2	9	9
889	A:A:E186	A:A:H188	2.46	No	No	0	9	3
890	A:A:E186	A:A:F199	8.16	No	Yes	2	9	5
891	A:A:E186	B:B:W99	4.36	No	Yes	2	9	9
892	A:A:H188	A:A:H195	4.78	No	No	0	3	4
893	A:A:H188	A:A:K197	13.1	No	No	0	3	6
894	A:A:F189	A:A:F191	2.14	Yes	Yes	3	9	5
895	A:A:F189	A:A:F196	9.65	Yes	Yes	3	9	7
896	A:A:F189	A:A:M198	4.98	Yes	Yes	3	9	7
897	A:A:F189	A:A:V332	2.62	Yes	No	3	9	7
898	A:A:H195	A:A:T190	5.48	No	No	0	4	3
899	A:A:F191	A:A:K192	9.93	Yes	No	3	5	4
900	A:A:F191	A:A:V332	3.93	Yes	No	3	5	7
901	A:A:F191	A:A:Q333	2.34	Yes	No	0	5	5
902	A:A:F191	A:A:F336	5.36	Yes	Yes	3	5	8
903	A:A:F336	A:A:K192	4.96	Yes	No	3	8	4
904	A:A:F196	A:A:L194	8.53	Yes	No	3	7	4
905	A:A:F336	A:A:L194	3.65	Yes	No	3	8	4
906	A:A:F196	A:A:F336	2.14	Yes	Yes	3	7	8
907	A:A:F196	A:A:V339	3.93	Yes	No	3	7	8
908	A:A:F199	A:A:K197	3.72	Yes	No	0	5	6
909	A:A:F199	A:A:F215	4.29	Yes	Yes	2	5	9
910	A:A:F199	B:B:W99	14.03	Yes	Yes	2	5	9
911	A:A:D200	A:A:T202	11.56	No	No	18	9	9
912	A:A:V201	A:A:W211	7.36	Yes	Yes	2	9	9
913	A:A:F215	A:A:V201	3.93	Yes	Yes	2	9	9
914	A:A:Q204	A:A:W211	3.29	Yes	Yes	2	9	9
915	A:A:Q204	B:B:L117	5.32	Yes	Yes	2	9	9
916	A:A:Q204	B:B:N119	3.96	Yes	Yes	2	9	9
917	A:A:Q204	B:B:Y145	4.51	Yes	Yes	2	9	8
918	A:A:S206	B:B:G144	1.86	No	No	0	8	8
919	A:A:S206	B:B:Y145	5.09	No	Yes	0	8	8
920	A:A:E207	A:A:K209	10.8	No	No	0	9	8
921	A:A:E207	B:B:D186	2.6	No	Yes	2	9	9
922	A:A:E207	B:B:C204	3.04	No	Yes	2	9	7
923	A:A:R208	A:A:W211	2	Yes	Yes	2	9	9
924	A:A:I212	A:A:R208	3.76	Yes	Yes	2	8	9
925	A:A:L249	A:A:R208	2.43	No	Yes	0	9	9
926	A:A:R208	A:A:S252	2.64	Yes	No	0	9	7
927	A:A:I253	A:A:R208	3.76	No	Yes	0	8	9
928	A:A:K209	B:B:D228	2.77	No	No	0	8	9
929	A:A:K210	B:B:Y145	3.58	Yes	Yes	2	9	8
930	A:A:K210	B:B:M188	10.08	Yes	No	2	9	8
931	A:A:K210	B:B:D228	11.06	Yes	No	0	9	9
932	A:A:K210	B:B:N230	2.8	Yes	No	2	9	9
933	A:A:I212	A:A:W211	3.52	Yes	Yes	2	8	9
934	A:A:F215	A:A:W211	4.01	Yes	Yes	2	9	9
935	A:A:W211	B:B:L117	2.28	Yes	Yes	2	9	9
936	A:A:W211	B:B:Y145	1.93	Yes	Yes	2	9	8
937	A:A:I212	A:A:W258	2.35	Yes	Yes	2	8	5
938	A:A:F259	A:A:I212	3.77	Yes	Yes	2	9	8
939	A:A:H213	A:A:W258	7.41	No	Yes	2	8	5
940	A:A:H213	B:B:Y59	7.62	No	Yes	2	8	8
941	A:A:H213	B:B:W332	5.29	No	Yes	2	8	9
942	A:A:C214	B:B:Y59	5.38	No	Yes	2	7	8
943	A:A:C214	B:B:Q75	4.58	No	No	2	7	9
944	A:A:F215	A:A:V218	2.62	Yes	No	0	9	9
945	A:A:F215	B:B:W99	4.01	Yes	Yes	2	9	9
946	A:A:F215	B:B:L117	2.44	Yes	Yes	2	9	9
947	A:A:E216	A:A:W258	6.54	No	Yes	0	7	5
948	A:A:E216	B:B:K57	6.75	No	No	0	7	9
949	A:A:F259	A:A:I221	6.28	Yes	No	2	9	8
950	A:A:I221	A:A:T262	4.56	No	No	2	8	7
951	A:A:I222	A:A:I265	2.94	No	Yes	3	7	8
952	A:A:F267	A:A:I222	2.51	Yes	No	3	9	7
953	A:A:F223	A:A:V225	2.62	Yes	No	0	9	7
954	A:A:F223	A:A:L249	6.09	Yes	No	0	9	9
955	A:A:F223	A:A:F250	9.65	Yes	Yes	4	9	9
956	A:A:F223	A:A:L266	3.65	Yes	Yes	4	9	9
957	A:A:L268	A:A:V225	4.47	Yes	No	0	8	7
958	A:A:F307	A:A:V225	5.24	Yes	No	0	8	7
959	A:A:L227	A:A:L268	5.54	Yes	Yes	4	7	8
960	A:A:F274	A:A:L227	3.65	Yes	Yes	4	9	7
961	A:A:I303	A:A:L227	4.28	Yes	Yes	4	7	7
962	A:A:F323	A:A:L227	2.44	Yes	Yes	4	4	7
963	A:A:K270	A:A:S228	4.59	No	No	0	9	9
964	A:A:L273	A:A:S228	3	No	No	0	6	9
965	A:A:D229	A:A:L232	4.07	No	Yes	4	8	8
966	A:A:D229	A:A:R242	17.87	No	No	4	8	9
967	A:A:D231	A:A:Y230	6.9	No	Yes	4	9	8
968	A:A:F274	A:A:Y230	5.16	Yes	Yes	4	9	8
969	A:A:K277	A:A:Y230	4.78	No	Yes	4	9	8
970	A:A:I278	A:A:Y230	3.63	No	Yes	4	6	8
971	A:A:L283	A:A:Y230	5.86	No	Yes	0	7	8
972	A:A:C286	A:A:Y230	2.69	Yes	Yes	4	6	8
973	A:A:D231	A:A:L232	6.79	No	Yes	4	9	8
974	A:A:D231	A:A:K277	13.83	No	No	4	9	9
975	A:A:L232	A:A:R242	6.07	Yes	No	4	8	9
976	A:A:K277	A:A:L232	4.23	No	Yes	4	9	8
977	A:A:E236	A:A:L234	7.95	No	No	0	9	8
978	A:A:D237	A:A:L234	5.43	No	No	0	8	8
979	A:A:H244	A:A:N241	8.93	No	No	4	4	9
980	A:A:C286	A:A:N241	3.15	Yes	No	4	6	9
981	A:A:M243	A:A:Y287	2.39	No	Yes	4	8	7
982	A:A:I303	A:A:M243	5.83	Yes	No	4	7	8
983	A:A:F307	A:A:M243	2.49	Yes	No	4	8	8
984	A:A:C286	A:A:H244	5.9	Yes	No	4	6	4
985	A:A:M247	A:A:Y287	3.59	No	Yes	0	6	7
986	A:A:F307	A:A:M247	4.98	Yes	No	0	8	6
987	A:A:C254	A:A:F250	2.79	Yes	Yes	4	5	9
988	A:A:F250	A:A:I264	3.77	Yes	No	4	9	6
989	A:A:F250	A:A:L266	2.44	Yes	Yes	4	9	9
990	A:A:F250	A:A:F307	7.5	Yes	Yes	4	9	8
991	A:A:F250	A:A:I319	5.02	Yes	No	0	9	5
992	A:A:D251	A:A:N255	5.39	No	No	0	5	8
993	A:A:D251	A:A:L310	10.86	No	No	0	5	4
994	A:A:C254	A:A:N255	3.15	Yes	No	0	5	8
995	A:A:C254	A:A:I264	3.27	Yes	No	4	5	6
996	A:A:C254	A:A:N311	6.3	Yes	No	4	5	8
997	A:A:C254	A:A:K317	4.85	Yes	No	4	5	7
998	A:A:K312	A:A:N255	11.19	No	No	0	5	8
999	A:A:K257	A:A:N256	2.8	No	No	2	4	8
1000	A:A:N256	A:A:W258	6.78	No	Yes	2	8	5
1001	A:A:F259	A:A:N256	3.62	Yes	No	2	9	8
1002	A:A:K257	A:A:W258	11.6	No	Yes	2	4	5
1003	A:A:F259	A:A:W258	3.01	Yes	Yes	2	9	5
1004	A:A:W258	B:B:R314	3	Yes	Yes	2	5	8
1005	A:A:W258	B:B:W332	2.81	Yes	Yes	2	5	9
1006	A:A:F259	A:A:T262	5.19	Yes	No	2	9	7
1007	A:A:R313	A:A:T260	5.17	Yes	No	0	4	3
1008	A:A:D261	A:A:T316	4.34	No	No	0	4	3
1009	A:A:S263	A:A:Y320	3.82	No	Yes	3	7	7
1010	A:A:S263	A:A:V342	3.23	No	No	3	7	7
1011	A:A:F267	A:A:I265	3.77	Yes	Yes	3	9	8
1012	A:A:F334	A:A:I265	2.51	Yes	Yes	3	3	8
1013	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
1014	A:A:L266	A:A:L268	2.77	Yes	Yes	4	9	8
1015	A:A:F307	A:A:L266	2.44	Yes	Yes	4	8	9
1016	A:A:L266	A:A:T321	4.42	Yes	Yes	4	9	5
1017	A:A:F267	A:A:H322	3.39	Yes	No	3	9	9
1018	A:A:F267	A:A:T324	3.89	Yes	No	3	9	9
1019	A:A:F267	A:A:N331	3.62	Yes	No	3	9	8
1020	A:A:F267	A:A:F334	2.14	Yes	Yes	3	9	3
1021	A:A:F267	A:A:V335	3.93	Yes	No	0	9	8
1022	A:A:L268	A:A:T321	2.95	Yes	Yes	4	8	5
1023	A:A:F323	A:A:L268	6.09	Yes	Yes	4	4	8
1024	A:A:K270	A:A:N269	2.8	No	No	0	9	9
1025	A:A:N269	A:A:T324	8.77	No	No	0	9	9
1026	A:A:D272	A:A:K271	4.15	No	No	0	9	5
1027	A:A:K271	A:A:Y296	4.78	No	Yes	0	5	4
1028	A:A:F274	A:A:I278	7.54	Yes	No	4	9	6
1029	A:A:F274	A:A:Y296	4.13	Yes	Yes	4	9	4
1030	A:A:A299	A:A:F274	2.77	No	Yes	0	7	9
1031	A:A:F274	A:A:I303	2.51	Yes	Yes	4	9	7
1032	A:A:E275	A:A:Y296	6.73	No	Yes	0	5	4
1033	A:A:E276	A:A:K280	2.7	No	No	0	5	1
1034	A:A:I278	A:A:N294	7.08	No	No	0	6	3
1035	A:A:P282	A:A:S281	3.56	No	No	0	5	7
1036	A:A:L283	A:A:Y287	7.03	No	Yes	0	7	7
1037	A:A:L283	A:A:Y290	5.86	No	Yes	0	7	7
1038	A:A:C286	A:A:Y287	9.41	Yes	Yes	4	6	7
1039	A:A:E289	A:A:Y287	5.61	No	Yes	4	6	7
1040	A:A:Y287	A:A:Y302	5.96	Yes	Yes	4	7	6
1041	A:A:I303	A:A:Y287	7.25	Yes	Yes	4	7	7
1042	A:A:E289	A:A:P288	6.29	No	No	0	6	5
1043	A:A:E289	A:A:Y302	3.37	No	Yes	4	6	6
1044	A:A:G292	A:A:Y290	4.35	No	Yes	4	7	7
1045	A:A:E298	A:A:Y290	12.35	Yes	Yes	4	4	7
1046	A:A:Y290	A:A:Y302	10.92	Yes	Yes	4	7	6
1047	A:A:E298	A:A:G292	4.91	Yes	No	4	4	7
1048	A:A:S293	A:A:T295	7.99	No	No	4	3	5
1049	A:A:E298	A:A:S293	7.19	Yes	No	4	4	3
1050	A:A:E298	A:A:T295	5.64	Yes	No	4	4	5
1051	A:A:A300	A:A:Y296	4	No	Yes	4	5	4
1052	A:A:F323	A:A:Y296	3.09	Yes	Yes	4	4	4
1053	A:A:A300	A:A:F323	2.77	No	Yes	4	5	4
1054	A:A:Q306	A:A:Y302	2.25	No	Yes	0	5	6
1055	A:A:F307	A:A:I303	2.51	Yes	Yes	4	8	7
1056	A:A:E308	A:A:Q304	7.65	No	No	4	3	5
1057	A:A:Q304	A:A:T321	17.01	No	Yes	4	5	5
1058	A:A:F323	A:A:Q304	4.68	Yes	No	4	4	5
1059	A:A:E308	A:A:T321	5.64	No	Yes	4	3	5
1060	A:A:K317	A:A:N311	5.6	No	No	4	7	8
1061	A:A:I319	A:A:N311	5.66	No	No	0	5	8
1062	A:A:R313	A:A:T316	2.59	Yes	No	0	4	3
1063	A:A:E318	A:A:Y320	12.35	No	Yes	3	4	7
1064	A:A:E318	A:A:K345	4.05	No	Yes	3	4	5
1065	A:A:F334	A:A:Y320	3.09	Yes	Yes	3	3	7
1066	A:A:A338	A:A:Y320	4	No	Yes	0	6	7
1067	A:A:D341	A:A:Y320	5.75	No	Yes	3	8	7
1068	A:A:V342	A:A:Y320	2.52	No	Yes	3	7	7
1069	A:A:K345	A:A:Y320	2.39	Yes	Yes	3	5	7
1070	A:A:F334	A:A:H322	15.84	Yes	No	3	3	9
1071	A:A:N331	A:A:T324	2.92	No	No	3	8	9
1072	A:A:C325	A:A:T327	5.07	No	No	24	7	8
1073	A:A:C325	A:A:K330	11.32	No	No	24	7	4
1074	A:A:T327	A:A:T329	3.14	No	No	0	8	9
1075	A:A:K330	A:A:T327	3	No	No	24	4	8
1076	A:A:D337	A:A:Q333	5.22	No	No	0	4	5
1077	A:A:D337	A:A:F336	2.39	No	Yes	0	4	8
1078	A:A:F336	A:A:T340	5.19	Yes	No	0	8	6
1079	A:A:I343	A:A:V339	3.07	No	No	0	7	8
1080	A:A:D341	A:A:K345	5.53	No	Yes	3	8	5
1081	A:A:N346	A:A:V342	4.43	No	No	0	4	7
1082	A:A:L348	A:A:L353	2.77	Yes	Yes	3	9	7
1083	A:A:F354	A:A:L348	2.44	Yes	Yes	0	5	9
1084	A:A:F354	A:A:K349	4.96	Yes	No	0	5	5
1085	B:B:L7	G:G:A12	3.15	No	No	0	8	5
1086	B:B:L7	G:G:R13	2.43	No	No	15	8	6
1087	B:B:L7	G:G:V16	2.98	No	Yes	15	8	7
1088	B:B:Q9	B:B:R8	2.34	No	No	0	3	3
1089	B:B:E12	B:B:R8	17.45	No	No	0	4	3
1090	B:B:E10	G:G:V16	4.28	No	Yes	15	8	7
1091	B:B:E10	G:G:K20	6.75	No	No	15	8	6
1092	B:B:L14	G:G:L19	8.3	No	No	0	8	9
1093	B:B:L14	G:G:K20	4.23	No	No	0	8	6
1094	B:B:K15	G:G:L19	5.64	No	No	0	6	9
1095	B:B:N16	B:B:R19	10.85	No	No	0	1	4
1096	B:B:I18	B:B:R22	5.01	Yes	No	0	7	6
1097	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
1098	B:B:I18	G:G:R27	3.76	Yes	Yes	0	7	8
1099	B:B:K23	B:B:R19	8.66	No	No	0	2	4
1100	B:B:A21	G:G:R27	2.77	No	Yes	0	4	8
1101	B:B:D258	B:B:R22	8.34	Yes	No	0	7	6
1102	B:B:Q259	B:B:R22	4.67	No	No	0	6	6
1103	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
1104	B:B:D27	G:G:K29	4.15	No	No	0	8	4
1105	B:B:D27	G:G:S31	2.94	No	No	0	8	9
1106	B:B:A28	B:B:Q32	3.03	No	No	0	4	1
1107	B:B:Q32	B:B:T29	11.34	No	No	0	1	3
1108	B:B:L30	B:B:T34	5.9	Yes	Yes	0	5	5
1109	B:B:L261	B:B:L30	5.54	No	Yes	0	5	5
1110	B:B:L30	B:B:M262	7.07	Yes	No	0	5	4
1111	B:B:L30	G:G:A34	3.15	Yes	No	0	5	6
1112	B:B:I33	G:G:A34	3.25	No	No	0	3	6
1113	B:B:I37	B:B:T34	3.04	Yes	Yes	0	2	5
1114	B:B:I37	B:B:R283	2.51	Yes	Yes	10	2	9
1115	B:B:I37	B:B:L300	2.85	Yes	No	10	2	6
1116	B:B:I37	B:B:K301	5.82	Yes	Yes	0	2	5
1117	B:B:D38	B:B:P39	3.22	No	No	0	1	1
1118	B:B:K301	B:B:P39	6.69	Yes	No	0	5	1
1119	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
1120	B:B:R283	B:B:V40	6.54	Yes	Yes	10	9	3
1121	B:B:D298	B:B:V40	4.38	No	Yes	10	9	3
1122	B:B:V40	G:G:L51	2.98	Yes	Yes	10	3	6
1123	B:B:I43	B:B:M45	2.92	No	No	0	3	4
1124	B:B:L308	B:B:M45	4.24	No	No	0	7	4
1125	B:B:M45	B:B:V327	3.04	No	Yes	0	4	6
1126	B:B:K337	B:B:T47	4.5	Yes	No	11	6	3
1127	B:B:T47	B:B:W339	2.43	No	Yes	11	3	9
1128	B:B:N340	B:B:R48	2.41	No	No	6	9	7
1129	B:B:R48	G:G:F61	4.28	No	Yes	6	7	8
1130	B:B:I338	B:B:R49	2.51	Yes	No	6	5	7
1131	B:B:R49	G:G:F61	6.41	No	Yes	6	7	8
1132	B:B:R52	B:B:T50	5.17	No	No	0	7	3
1133	B:B:K337	B:B:T50	6.01	Yes	No	0	6	3
1134	B:B:L51	B:B:L70	2.77	Yes	Yes	6	9	5
1135	B:B:L51	B:B:W82	13.67	Yes	Yes	6	9	9
1136	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
1137	B:B:L336	B:B:L51	5.54	Yes	Yes	6	7	9
1138	B:B:I338	B:B:L51	2.85	Yes	Yes	6	5	9
1139	B:B:F335	B:B:R52	3.21	No	No	0	4	7
1140	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
1141	B:B:H54	B:B:I58	7.95	Yes	No	0	9	9
1142	B:B:H54	B:B:S72	9.76	Yes	No	6	9	9
1143	B:B:H54	B:B:S74	12.55	Yes	No	6	9	9
1144	B:B:D76	B:B:H54	6.3	Yes	Yes	6	9	9
1145	B:B:H54	B:B:I80	6.63	Yes	Yes	6	9	8
1146	B:B:H54	B:B:W82	3.17	Yes	Yes	6	9	9
1147	B:B:K57	B:B:Y59	3.58	No	Yes	2	9	8
1148	B:B:K57	B:B:W332	19.73	No	Yes	2	9	9
1149	B:B:Q75	B:B:Y59	11.27	No	Yes	2	9	8
1150	B:B:W332	B:B:Y59	5.79	Yes	Yes	2	9	8
1151	B:B:A60	B:B:C103	3.61	No	No	0	7	8
1152	B:B:M61	B:B:W63	4.65	No	Yes	6	6	7
1153	B:B:C317	B:B:M61	6.48	No	No	0	7	6
1154	B:B:A328	B:B:M61	3.22	No	No	6	5	6
1155	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
1156	B:B:H62	B:B:R150	11.28	No	Yes	0	6	6
1157	B:B:L70	B:B:W63	9.11	Yes	Yes	6	5	7
1158	B:B:S84	B:B:W63	7.41	Yes	Yes	6	5	7
1159	B:B:G319	B:B:W63	2.81	No	Yes	6	5	7
1160	B:B:T321	B:B:W63	9.7	Yes	Yes	6	7	7
1161	B:B:A328	B:B:W63	3.89	No	Yes	6	5	7
1162	B:B:G64	B:B:Y105	2.9	No	Yes	0	5	6
1163	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1164	B:B:D322	B:B:T65	2.89	No	No	0	1	1
1165	B:B:D66	B:B:R68	3.57	No	Yes	6	8	5
1166	B:B:D66	B:B:L69	2.71	No	Yes	6	8	5
1167	B:B:S67	B:B:T321	4.8	No	Yes	6	5	7
1168	B:B:D323	B:B:S67	10.31	No	No	6	7	5
1169	B:B:L69	B:B:R68	2.43	Yes	Yes	6	5	5
1170	B:B:D83	B:B:R68	15.48	No	Yes	6	8	5
1171	B:B:R68	B:B:Y85	16.46	Yes	No	6	5	4
1172	B:B:I81	B:B:L69	2.85	Yes	Yes	0	7	5
1173	B:B:D83	B:B:L69	5.43	No	Yes	6	8	5
1174	B:B:L69	B:B:Y105	3.52	Yes	Yes	0	5	6
1175	B:B:L70	B:B:W82	6.83	Yes	Yes	6	5	9
1176	B:B:L70	B:B:S84	3	Yes	Yes	6	5	5
1177	B:B:L79	B:B:V71	4.47	No	Yes	0	7	8
1178	B:B:I81	B:B:V71	4.61	Yes	Yes	0	7	8
1179	B:B:C103	B:B:V71	1.71	No	Yes	0	8	8
1180	B:B:V71	B:B:Y105	3.79	Yes	Yes	0	8	6
1181	B:B:S72	B:B:W82	6.18	No	Yes	6	9	9
1182	B:B:L336	B:B:S72	3	Yes	No	6	7	9
1183	B:B:A73	B:B:C103	3.61	No	No	0	9	8
1184	B:B:D76	B:B:S74	10.31	Yes	No	6	9	9
1185	B:B:Q75	B:B:W99	4.38	No	Yes	2	9	9
1186	B:B:D76	B:B:K78	8.3	Yes	Yes	0	9	8
1187	B:B:G77	B:B:L95	1.71	No	Yes	0	8	8
1188	B:B:G77	B:B:S98	1.86	No	No	0	8	8
1189	B:B:K78	B:B:P94	3.35	Yes	No	0	8	5
1190	B:B:I93	B:B:L79	2.85	Yes	No	0	7	7
1191	B:B:L79	B:B:L95	2.77	No	Yes	0	7	8
1192	B:B:I80	B:B:W82	12.92	Yes	Yes	6	8	9
1193	B:B:I80	B:B:K89	2.91	Yes	Yes	6	8	9
1194	B:B:H91	B:B:I81	5.3	Yes	Yes	0	5	7
1195	B:B:I81	B:B:I93	2.94	Yes	Yes	0	7	7
1196	B:B:K89	B:B:W82	10.44	Yes	Yes	6	9	9
1197	B:B:L336	B:B:W82	3.42	Yes	Yes	6	7	9
1198	B:B:D83	B:B:T86	4.34	No	No	0	8	6
1199	B:B:I338	B:B:S84	3.1	Yes	Yes	6	5	5
1200	B:B:S84	G:G:F61	2.64	Yes	Yes	6	5	8
1201	B:B:Y85	G:G:P60	9.74	No	Yes	6	4	9
1202	B:B:Y85	G:G:F61	5.16	No	Yes	6	4	8
1203	B:B:N88	B:B:T86	11.7	No	No	0	7	6
1204	B:B:H91	B:B:V90	6.92	Yes	No	0	5	5
1205	B:B:H91	B:B:L126	6.43	Yes	No	0	5	5
1206	B:B:H91	B:B:V133	4.15	Yes	No	0	5	4
1207	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
1208	B:B:I93	B:B:Y124	4.84	Yes	Yes	13	7	6
1209	B:B:I93	B:B:V133	10.75	Yes	No	13	7	4
1210	B:B:L95	B:B:V100	2.98	Yes	No	13	8	9
1211	B:B:C114	B:B:L95	4.76	No	Yes	13	8	8
1212	B:B:L95	B:B:Y124	4.69	Yes	Yes	13	8	6
1213	B:B:E138	B:B:R96	2.33	No	No	0	6	6
1214	B:B:D118	B:B:S97	8.83	No	No	0	9	8
1215	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
1216	B:B:L117	B:B:W99	4.56	Yes	Yes	2	9	9
1217	B:B:C114	B:B:V100	3.42	No	No	13	8	9
1218	B:B:G116	B:B:M101	1.75	No	No	0	9	9
1219	B:B:L117	B:B:M101	4.24	Yes	No	2	9	9
1220	B:B:M101	B:B:Y145	3.59	No	Yes	2	9	8
1221	B:B:G115	B:B:T102	1.82	Yes	No	0	9	8
1222	B:B:C148	B:B:T102	3.38	Yes	No	0	6	8
1223	B:B:C149	B:B:T102	3.38	Yes	No	0	8	8
1224	B:B:A104	B:B:A113	1.79	No	Yes	2	7	9
1225	B:B:A104	B:B:C149	1.81	No	Yes	2	7	8
1226	B:B:A104	B:B:F151	2.77	No	Yes	2	7	9
1227	B:B:G109	B:B:Y105	4.35	No	Yes	0	5	6
1228	B:B:V112	B:B:Y105	3.79	No	Yes	0	8	6
1229	B:B:L126	B:B:Y105	3.52	No	Yes	0	5	6
1230	B:B:A106	B:B:P107	1.87	No	No	2	6	6
1231	B:B:A106	B:B:F151	8.32	No	Yes	2	6	9
1232	B:B:F151	B:B:P107	2.89	Yes	No	2	9	6
1233	B:B:N110	B:B:S108	4.47	No	No	0	4	6
1234	B:B:D154	B:B:S108	8.83	No	No	0	6	6
1235	B:B:N110	B:B:Y111	3.49	No	Yes	0	4	4
1236	B:B:K127	B:B:N110	2.8	No	No	0	4	4
1237	B:B:I123	B:B:Y111	4.84	No	Yes	2	6	4
1238	B:B:N125	B:B:Y111	11.63	No	Yes	0	4	4
1239	B:B:S136	B:B:Y111	3.82	No	Yes	0	4	4
1240	B:B:F151	B:B:Y111	2.06	Yes	Yes	2	9	4
1241	B:B:D154	B:B:Y111	6.9	No	Yes	0	6	4
1242	B:B:V112	B:B:Y124	3.79	No	Yes	0	8	6
1243	B:B:A113	B:B:C121	1.81	Yes	No	2	9	8
1244	B:B:A113	B:B:C149	1.81	Yes	Yes	2	9	8
1245	B:B:A113	B:B:F151	2.77	Yes	Yes	2	9	9
1246	B:B:C114	B:B:G115	3.92	No	Yes	0	8	9
1247	B:B:G115	B:B:G116	2.11	Yes	No	0	9	9
1248	B:B:G115	B:B:L146	1.71	Yes	Yes	0	9	7
1249	B:B:L117	B:B:Y145	2.34	Yes	Yes	2	9	8
1250	B:B:D118	B:B:I120	4.2	No	Yes	0	9	6
1251	B:B:G144	B:B:N119	3.39	No	Yes	0	8	9
1252	B:B:E138	B:B:I120	2.73	No	Yes	0	6	6
1253	B:B:A140	B:B:I120	3.25	No	Yes	0	5	6
1254	B:B:C121	B:B:L146	3.17	No	Yes	2	8	7
1255	B:B:C121	B:B:C149	1.82	No	Yes	2	8	8
1256	B:B:S122	B:B:Y124	5.09	No	Yes	0	8	6
1257	B:B:E138	B:B:S122	2.87	No	No	0	6	8
1258	B:B:I123	B:B:L139	4.28	No	No	0	6	9
1259	B:B:F151	B:B:I123	2.51	Yes	No	2	9	6
1260	B:B:V133	B:B:Y124	3.79	No	Yes	13	4	6
1261	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
1262	B:B:N125	B:B:T128	5.85	No	Yes	0	4	3
1263	B:B:E130	B:B:T128	11.29	Yes	Yes	25	3	3
1264	B:B:G131	B:B:T128	1.82	No	Yes	0	4	3
1265	B:B:R134	B:B:T128	6.47	No	Yes	25	3	3
1266	B:B:E130	B:B:N132	9.2	Yes	No	0	3	3
1267	B:B:E130	B:B:R134	2.33	Yes	No	25	3	3
1268	B:B:L139	B:B:R137	2.43	No	No	0	9	5
1269	B:B:L139	B:B:W169	17.08	No	Yes	0	9	8
1270	B:B:A140	B:B:G141	1.95	No	No	0	5	5
1271	B:B:H142	B:B:L146	2.57	Yes	Yes	2	9	7
1272	B:B:H142	B:B:T159	5.48	Yes	Yes	2	9	9
1273	B:B:H142	B:B:S161	16.74	Yes	Yes	2	9	9
1274	B:B:D163	B:B:H142	6.3	Yes	Yes	2	9	9
1275	B:B:H142	B:B:T165	2.74	Yes	No	2	9	7
1276	B:B:H142	B:B:W169	4.23	Yes	Yes	2	9	8
1277	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
1278	B:B:G162	B:B:Y145	4.35	No	Yes	2	9	8
1279	B:B:D186	B:B:Y145	5.75	Yes	Yes	2	9	8
1280	B:B:L146	B:B:T159	5.9	Yes	Yes	2	7	9
1281	B:B:L146	B:B:S161	6.01	Yes	Yes	2	7	9
1282	B:B:S147	B:B:S160	3.26	No	Yes	0	9	6
1283	B:B:C148	B:B:R150	5.57	Yes	Yes	8	6	6
1284	B:B:C148	B:B:S160	1.72	Yes	Yes	8	6	6
1285	B:B:C148	B:B:L190	3.17	Yes	Yes	8	6	5
1286	B:B:C149	B:B:T159	3.38	Yes	Yes	2	8	9
1287	B:B:L190	B:B:R150	2.43	Yes	Yes	8	5	6
1288	B:B:L192	B:B:R150	2.43	No	Yes	0	5	6
1289	B:B:F151	B:B:I157	5.02	Yes	No	0	9	7
1290	B:B:L152	B:B:Q156	2.66	No	No	0	3	5
1291	B:B:L152	B:B:L192	4.15	No	No	0	3	5
1292	B:B:L152	B:B:T196	2.95	No	No	0	3	1
1293	B:B:D153	B:B:Q156	6.53	No	No	0	5	5
1294	B:B:D170	B:B:N155	6.73	No	No	0	9	3
1295	B:B:E172	B:B:N155	7.89	No	No	0	6	3
1296	B:B:I157	B:B:W169	2.35	No	Yes	0	7	8
1297	B:B:I157	B:B:I171	2.94	No	No	0	7	6
1298	B:B:L190	B:B:V158	2.98	Yes	No	8	5	5
1299	B:B:F199	B:B:V158	3.93	Yes	No	8	9	5
1300	B:B:T159	B:B:W169	9.7	Yes	Yes	2	9	8
1301	B:B:C166	B:B:S160	3.44	Yes	Yes	8	8	6
1302	B:B:S160	B:B:V187	4.85	Yes	Yes	8	6	9
1303	B:B:L190	B:B:S160	4.5	Yes	Yes	8	5	6
1304	B:B:G162	B:B:S161	1.86	No	Yes	2	9	9
1305	B:B:D163	B:B:S161	4.42	Yes	Yes	2	9	9
1306	B:B:D186	B:B:G162	5.03	Yes	No	2	9	9
1307	B:B:D163	B:B:T165	14.45	Yes	No	2	9	7
1308	B:B:G185	B:B:T164	1.82	No	No	0	5	6
1309	B:B:C166	B:B:F180	2.79	Yes	Yes	8	8	7
1310	B:B:C166	B:B:V187	5.12	Yes	Yes	8	8	9
1311	B:B:C166	B:B:S201	3.44	Yes	Yes	8	8	9
1312	B:B:A167	B:B:Q176	4.55	No	No	0	4	4
1313	B:B:Q176	B:B:W169	9.86	No	Yes	0	4	8
1314	B:B:D170	B:B:T173	2.89	No	No	0	9	5
1315	B:B:Q175	B:B:T173	11.34	No	No	0	4	5
1316	B:B:Q176	B:B:T179	2.83	No	No	0	4	4
1317	B:B:T177	B:B:T178	3.14	No	No	0	4	4
1318	B:B:F180	B:B:T178	3.89	Yes	No	8	7	4
1319	B:B:G216	B:B:T178	1.82	No	No	8	4	4
1320	B:B:F180	B:B:F199	7.5	Yes	Yes	8	7	9
1321	B:B:F180	B:B:W211	12.03	Yes	Yes	8	7	8
1322	B:B:F180	B:B:G216	3.01	Yes	No	8	7	4
1323	B:B:G182	B:B:T181	3.64	No	Yes	0	6	2
1324	B:B:T181	G:G:K14	4.5	Yes	No	0	2	4
1325	B:B:H183	B:B:V187	5.54	Yes	Yes	8	9	9
1326	B:B:H183	B:B:S201	2.79	Yes	Yes	8	9	9
1327	B:B:A203	B:B:H183	8.78	No	Yes	8	8	9
1328	B:B:D205	B:B:H183	5.04	Yes	Yes	8	9	9
1329	B:B:H183	B:B:S207	2.79	Yes	No	8	9	5
1330	B:B:H183	B:B:K209	11.79	Yes	Yes	8	9	6
1331	B:B:H183	B:B:W211	2.12	Yes	Yes	8	9	8
1332	B:B:G185	B:B:T184	1.82	No	No	0	5	3
1333	B:B:D205	B:B:T184	7.23	Yes	No	0	9	3
1334	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
1335	B:B:C204	B:B:D186	6.22	Yes	Yes	2	7	9
1336	B:B:S201	B:B:V187	3.23	Yes	Yes	8	9	9
1337	B:B:C204	B:B:M188	3.24	Yes	No	2	7	8
1338	B:B:M188	B:B:N230	2.8	No	No	2	8	9
1339	B:B:G202	B:B:S189	1.86	No	No	0	6	7
1340	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
1341	B:B:F199	B:B:L190	6.09	Yes	Yes	8	9	5
1342	B:B:C233	B:B:S191	3.44	No	No	0	3	8
1343	B:B:F234	B:B:S191	3.96	Yes	No	0	5	8
1344	B:B:F199	B:B:L192	2.44	Yes	No	0	9	5
1345	B:B:A193	B:B:P194	1.87	No	No	2	4	4
1346	B:B:A193	B:B:D195	4.63	No	No	0	4	5
1347	B:B:A193	B:B:F234	4.16	No	Yes	2	4	5
1348	B:B:F234	B:B:P194	2.89	Yes	No	2	5	4
1349	B:B:G238	B:B:P194	4.06	No	No	0	7	4
1350	B:B:D195	B:B:R197	7.15	No	No	0	5	5
1351	B:B:R197	B:B:R214	12.79	No	No	0	5	9
1352	B:B:L198	B:B:L210	5.54	No	Yes	0	3	5
1353	B:B:D212	B:B:L198	5.43	No	No	0	9	3
1354	B:B:F199	B:B:W211	12.03	Yes	Yes	8	9	8
1355	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
1356	B:B:L210	B:B:V200	4.47	Yes	Yes	0	5	6
1357	B:B:I232	B:B:V200	4.61	Yes	Yes	2	8	6
1358	B:B:F234	B:B:V200	7.87	Yes	Yes	2	5	6
1359	B:B:F241	B:B:V200	5.24	Yes	Yes	2	6	6
1360	B:B:S201	B:B:W211	4.94	Yes	Yes	8	9	8
1361	B:B:A208	B:B:G202	1.95	No	No	0	6	6
1362	B:B:G202	B:B:I229	3.53	No	No	0	6	7
1363	B:B:A203	B:B:D205	3.09	No	Yes	8	8	9
1364	B:B:C204	B:B:D228	6.22	Yes	No	0	7	9
1365	B:B:D205	B:B:S207	10.31	Yes	No	8	9	5
1366	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
1367	B:B:K209	B:B:W211	5.8	Yes	Yes	8	6	8
1368	B:B:C218	B:B:K209	4.85	Yes	Yes	8	5	6
1369	B:B:K209	B:B:T221	10.51	Yes	No	0	6	7
1370	B:B:L210	B:B:Q220	2.66	Yes	Yes	0	5	7
1371	B:B:L210	B:B:L255	5.54	Yes	No	0	5	6
1372	B:B:C218	B:B:W211	3.92	Yes	Yes	8	5	8
1373	B:B:D212	B:B:E215	19.49	No	No	0	9	3
1374	B:B:R214	B:B:V213	2.62	No	No	0	9	4
1375	B:B:E215	B:B:R219	4.65	No	No	0	3	5
1376	B:B:M217	G:G:Q18	4.08	No	No	0	3	9
1377	B:B:M217	G:G:M21	2.89	No	No	0	3	1
1378	B:B:C218	G:G:Q18	4.58	Yes	No	8	5	9
1379	B:B:C218	G:G:E22	4.56	Yes	No	8	5	9
1380	B:B:F222	B:B:Q220	7.03	Yes	Yes	2	8	7
1381	B:B:D258	B:B:Q220	11.75	Yes	Yes	2	7	7
1382	B:B:Q220	G:G:I25	2.74	Yes	No	0	7	2
1383	B:B:T221	G:G:E22	5.64	No	No	0	7	9
1384	B:B:F222	B:B:F241	6.43	Yes	Yes	2	8	6
1385	B:B:F222	B:B:F253	7.5	Yes	Yes	2	8	6
1386	B:B:F222	B:B:L255	2.44	Yes	No	2	8	6
1387	B:B:D258	B:B:F222	5.97	Yes	Yes	2	7	8
1388	B:B:G224	B:B:T223	1.82	No	No	0	6	2
1389	B:B:H225	B:B:I229	7.95	Yes	No	2	9	7
1390	B:B:H225	B:B:T243	6.85	Yes	Yes	2	9	8
1391	B:B:H225	B:B:S245	12.55	Yes	No	2	9	9
1392	B:B:D247	B:B:H225	2.52	Yes	Yes	2	9	9
1393	B:B:H225	B:B:T249	2.74	Yes	Yes	2	9	6
1394	B:B:H225	B:B:R251	18.05	Yes	Yes	2	9	8
1395	B:B:E226	B:B:S227	5.75	No	No	2	3	6
1396	B:B:D247	B:B:E226	9.09	Yes	No	2	9	3
1397	B:B:D247	B:B:S227	4.42	Yes	No	2	9	6
1398	B:B:I229	B:B:T243	3.04	No	Yes	2	7	8
1399	B:B:D246	B:B:N230	5.39	No	No	0	9	9
1400	B:B:A231	B:B:V276	3.39	No	No	0	5	6
1401	B:B:F241	B:B:I232	7.54	Yes	Yes	2	6	8
1402	B:B:I232	B:B:T243	4.56	Yes	Yes	2	8	8
1403	B:B:F235	B:B:P236	10.11	Yes	Yes	2	6	7
1404	B:B:F235	B:B:N237	6.04	Yes	No	2	6	5
1405	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
1406	B:B:F235	B:B:F278	8.57	Yes	Yes	2	6	7
1407	B:B:F235	B:B:G282	6.02	Yes	No	2	6	9
1408	B:B:F235	G:G:L37	3.65	Yes	No	0	6	7
1409	B:B:F235	G:G:Y40	2.06	Yes	Yes	2	6	6
1410	B:B:F278	B:B:P236	2.89	Yes	Yes	2	7	7
1411	B:B:G282	B:B:P236	4.06	No	Yes	2	9	7
1412	B:B:P236	G:G:Y40	4.17	Yes	Yes	2	7	6
1413	B:B:N237	B:B:N239	6.81	No	No	0	5	2
1414	B:B:N237	G:G:Y40	13.96	No	Yes	2	5	6
1415	B:B:N239	B:B:R256	4.82	No	No	0	2	9
1416	B:B:F241	B:B:T243	2.59	Yes	Yes	2	6	8
1417	B:B:F241	B:B:F253	7.5	Yes	Yes	2	6	6
1418	B:B:F241	B:B:L255	2.44	Yes	No	2	6	6
1419	B:B:A242	B:B:F278	2.77	No	Yes	2	4	7
1420	B:B:A242	B:B:L285	3.15	No	Yes	2	4	6
1421	B:B:G244	B:B:T243	1.82	Yes	Yes	2	5	8
1422	B:B:F253	B:B:T243	5.19	Yes	Yes	2	6	8
1423	B:B:C250	B:B:G244	1.96	Yes	Yes	2	8	5
1424	B:B:G244	B:B:I273	3.53	Yes	Yes	2	5	6
1425	B:B:G244	B:B:V276	1.84	Yes	No	2	5	6
1426	B:B:D247	B:B:S245	7.36	Yes	No	2	9	9
1427	B:B:D247	B:B:T249	7.23	Yes	Yes	2	9	6
1428	B:B:R251	B:B:T249	6.47	Yes	Yes	2	8	6
1429	B:B:C250	B:B:Y264	2.69	Yes	Yes	2	8	5
1430	B:B:C250	B:B:I273	3.27	Yes	Yes	2	8	6
1431	B:B:C250	B:B:V276	1.71	Yes	No	2	8	6
1432	B:B:F253	B:B:R251	2.14	Yes	Yes	2	6	8
1433	B:B:E260	B:B:R251	13.96	No	Yes	2	6	8
1434	B:B:R251	B:B:T263	9.06	Yes	No	2	8	1
1435	B:B:L252	B:B:Y264	4.69	No	Yes	0	7	5
1436	B:B:E260	B:B:F253	2.33	No	Yes	2	6	6
1437	B:B:A257	B:B:D254	4.63	No	No	26	7	9
1438	B:B:D254	G:G:A33	6.18	No	No	26	9	7
1439	B:B:R256	G:G:I28	7.52	No	No	0	9	4
1440	B:B:R256	G:G:D36	5.96	No	No	0	9	5
1441	B:B:A257	G:G:A33	1.79	No	No	26	7	7
1442	B:B:D258	G:G:R27	5.96	Yes	Yes	0	7	8
1443	B:B:Q259	G:G:V30	2.87	No	No	0	6	8
1444	B:B:E260	B:B:T263	5.64	No	No	2	6	1
1445	B:B:L261	G:G:V30	2.98	No	No	0	5	8
1446	B:B:M262	B:B:Y264	7.18	No	Yes	2	4	5
1447	B:B:A302	B:B:M262	3.22	No	No	2	2	4
1448	B:B:L285	B:B:Y264	3.52	Yes	Yes	2	6	5
1449	B:B:W297	B:B:Y264	6.75	Yes	Yes	2	8	5
1450	B:B:A302	B:B:Y264	2.67	No	Yes	2	2	5
1451	B:B:H266	B:B:N268	2.55	No	No	0	4	4
1452	B:B:H266	B:B:I269	2.65	No	Yes	0	4	4
1453	B:B:H266	B:B:R304	6.77	No	No	0	4	5
1454	B:B:I269	B:B:Y289	7.25	Yes	Yes	2	4	7
1455	B:B:I269	B:B:W297	2.35	Yes	Yes	2	4	8
1456	B:B:C271	B:B:Y289	2.69	No	Yes	2	5	7
1457	B:B:C271	B:B:D290	6.22	No	Yes	2	5	6
1458	B:B:C271	B:B:D291	6.22	No	No	2	5	8
1459	B:B:G272	B:B:I273	1.76	No	Yes	0	4	6
1460	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
1461	B:B:I273	B:B:Y289	9.67	Yes	Yes	2	6	7
1462	B:B:G288	B:B:T274	1.82	Yes	No	0	7	8
1463	B:B:D290	B:B:T274	4.34	Yes	No	2	6	8
1464	B:B:R314	B:B:T274	2.59	Yes	No	2	8	8
1465	B:B:G288	B:B:S275	1.86	Yes	No	0	7	8
1466	B:B:L318	B:B:S275	3	Yes	No	0	6	8
1467	B:B:L318	B:B:S277	3	Yes	No	6	6	5
1468	B:B:G319	B:B:S277	1.86	No	No	6	5	5
1469	B:B:S277	B:B:V320	3.23	No	No	0	5	7
1470	B:B:F278	B:B:L285	7.31	Yes	Yes	2	7	6
1471	B:B:S279	G:G:D48	7.36	No	Yes	10	9	9
1472	B:B:S279	G:G:L50	4.5	No	No	10	9	9
1473	B:B:G324	B:B:K280	3.49	No	No	0	9	1
1474	B:B:K280	G:G:E47	2.7	No	No	0	1	3
1475	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
1476	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
1477	B:B:D298	B:B:R283	13.1	No	Yes	10	9	9
1478	B:B:L300	B:B:R283	9.72	No	Yes	10	6	9
1479	B:B:R283	G:G:L51	7.29	Yes	Yes	10	9	6
1480	B:B:L284	B:B:V296	5.96	No	No	0	5	5
1481	B:B:L284	G:G:L51	4.15	No	Yes	0	5	6
1482	B:B:L285	B:B:W297	2.28	Yes	Yes	2	6	8
1483	B:B:L286	B:B:V296	4.47	No	No	0	7	5
1484	B:B:L286	B:B:L318	2.77	No	Yes	0	7	6
1485	B:B:A287	B:B:G288	1.95	No	Yes	0	6	7
1486	B:B:A287	B:B:W297	2.59	No	Yes	0	6	8
1487	B:B:G288	B:B:V315	1.84	Yes	No	0	7	7
1488	B:B:D291	B:B:Y289	3.45	No	Yes	2	8	7
1489	B:B:N295	B:B:Y289	9.3	Yes	Yes	2	6	7
1490	B:B:W297	B:B:Y289	5.79	Yes	Yes	2	8	7
1491	B:B:D290	B:B:R314	17.87	Yes	Yes	2	6	8
1492	B:B:D291	B:B:N293	8.08	No	No	0	8	5
1493	B:B:F292	B:B:N313	3.62	No	No	0	4	7
1494	B:B:A309	B:B:N293	3.13	No	No	0	3	5
1495	B:B:C294	B:B:L308	4.76	No	No	0	5	7
1496	B:B:N295	B:B:W297	4.52	Yes	Yes	2	6	8
1497	B:B:N295	B:B:R304	7.23	Yes	No	0	6	5
1498	B:B:N295	B:B:V307	5.91	Yes	No	0	6	3
1499	B:B:G306	B:B:V296	1.84	No	No	0	4	5
1500	B:B:D298	B:B:K301	4.15	No	Yes	0	9	5
1501	B:B:L300	G:G:C41	6.35	No	No	0	6	7
1502	B:B:L308	B:B:W339	17.08	No	Yes	0	7	9
1503	B:B:G310	B:B:K337	1.74	No	Yes	0	5	6
1504	B:B:H311	B:B:V315	4.15	Yes	No	11	9	7
1505	B:B:H311	B:B:T329	5.48	Yes	No	0	9	8
1506	B:B:H311	B:B:S331	16.74	Yes	No	11	9	9
1507	B:B:D333	B:B:H311	7.56	Yes	Yes	11	9	9
1508	B:B:H311	B:B:K337	5.24	Yes	Yes	11	9	6
1509	B:B:D312	B:B:D333	3.99	No	Yes	0	5	9
1510	B:B:N313	B:B:W332	4.52	No	Yes	0	7	9
1511	B:B:R314	B:B:W332	12	Yes	Yes	2	8	9
1512	B:B:S331	B:B:V315	3.23	No	No	11	9	7
1513	B:B:S316	B:B:W332	6.18	No	Yes	0	9	9
1514	B:B:C317	B:B:G330	1.96	No	No	0	7	5
1515	B:B:G319	B:B:L318	1.71	No	Yes	6	5	6
1516	B:B:L318	B:B:V327	2.98	Yes	Yes	0	6	6
1517	B:B:L318	B:B:T329	2.95	Yes	No	0	6	8
1518	B:B:V320	B:B:V327	3.21	No	Yes	0	7	6
1519	B:B:D323	B:B:T321	7.23	No	Yes	6	7	7
1520	B:B:G324	B:B:T321	1.82	No	Yes	0	9	7
1521	B:B:A326	B:B:T321	3.36	No	Yes	0	7	7
1522	B:B:D323	B:B:M325	8.32	No	No	0	7	5
1523	B:B:G324	G:G:P49	2.03	No	Yes	0	9	7
1524	B:B:M325	G:G:P49	5.03	No	Yes	0	5	7
1525	B:B:M325	G:G:P60	5.03	No	Yes	0	5	9
1526	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
1527	B:B:V327	B:B:W339	3.68	Yes	Yes	0	6	9
1528	B:B:T329	B:B:W339	8.49	No	Yes	0	8	9
1529	B:B:G330	B:B:L336	3.42	No	Yes	0	5	7
1530	B:B:D333	B:B:S331	8.83	Yes	No	11	9	9
1531	B:B:D333	B:B:F335	7.17	Yes	No	0	9	4
1532	B:B:K337	B:B:W339	5.8	Yes	Yes	11	6	9
1533	B:B:I338	G:G:F61	3.77	Yes	Yes	6	5	8
1534	B:B:N340	G:G:N59	5.45	No	No	0	9	9
1535	B:B:N340	G:G:F61	3.62	No	Yes	6	9	8
1536	G:G:R13	G:G:V16	2.62	No	Yes	15	6	7
1537	G:G:E17	G:G:R13	24.42	No	No	0	6	6
1538	G:G:K20	G:G:V16	4.55	No	Yes	15	6	7
1539	G:G:E22	G:G:Q18	10.19	No	No	8	9	9
1540	G:G:I25	G:G:R27	2.51	No	Yes	0	2	8
1541	G:G:I28	G:G:K32	4.36	No	No	0	4	5
1542	G:G:E42	G:G:M38	4.06	No	No	0	1	4
1543	G:G:H44	G:G:Y40	8.71	No	Yes	0	6	6
1544	G:G:A43	G:G:H44	2.93	No	No	0	4	6
1545	G:G:D48	G:G:P49	3.22	Yes	Yes	0	9	7
1546	G:G:D48	G:G:L50	2.71	Yes	No	10	9	9
1547	G:G:D48	G:G:L51	10.86	Yes	Yes	10	9	6
1548	G:G:P49	G:G:V54	3.53	Yes	No	0	7	6
1549	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1550	G:G:P55	G:G:V54	5.3	No	No	0	5	6
1551	G:G:E58	G:G:S57	5.75	No	No	0	5	6
1552	G:G:N59	G:G:P60	4.89	No	Yes	0	9	9
1553	G:G:F61	G:G:P60	2.89	Yes	Yes	6	8	9
1554	L:L:A19	L:L:V13	1.7	No	No	0	0	0
1555	L:L:G34	L:L:N35	1.7	No	No	0	0	0
1556	R:R:A100	R:R:V99	1.7	No	No	0	5	4
1557	B:B:A11	G:G:V16	1.7	No	Yes	0	5	7
1558	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
1559	L:L:A198	L:L:T211	1.68	No	No	0	0	0
1560	M:M:A9	M:M:T121	1.68	No	No	0	0	0
1561	M:M:A79	M:M:T72	1.68	No	No	0	0	0
1562	A:A:D26	A:A:G27	1.68	No	No	0	5	5
1563	M:M:K214	M:M:P215	1.67	No	Yes	0	0	0
1564	L:L:L11	L:L:P12	1.64	No	No	0	0	0
1565	L:L:G16	L:L:Q17	1.64	No	No	0	0	0
1566	R:R:L41	R:R:P42	1.64	No	No	0	6	5
1567	R:R:L125	R:R:P211	1.64	No	Yes	0	5	9
1568	R:R:L136	R:R:P147	1.64	Yes	No	0	5	4
1569	A:A:E216	A:A:G217	1.64	No	No	0	7	5
1570	B:B:G174	B:B:Q175	1.64	No	No	0	4	4
1571	L:L:S167	L:L:S181	1.63	No	No	0	0	0
1572	M:M:S200	M:M:S201	1.63	No	No	0	0	0
1573	A:A:N294	A:A:P282	1.63	No	No	0	3	5
1574	M:M:S7	M:M:V20	1.62	No	No	0	0	0
1575	M:M:S190	M:M:V182	1.62	No	No	0	0	0
1576	R:R:A289	R:R:I44	1.62	No	No	0	4	5
1577	A:A:I343	R:R:A141	1.62	No	No	0	7	8
1578	A:A:I344	R:R:A141	1.62	No	No	0	6	8
1579	A:A:A220	A:A:I265	1.62	No	Yes	0	8	8
1580	A:A:C325	A:A:K271	1.62	No	No	0	7	5
1581	B:B:A92	B:B:I80	1.62	No	Yes	0	6	8
1582	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
1583	G:G:A33	G:G:I28	1.62	No	No	0	7	4
1584	M:M:A16	M:M:K12	1.61	No	No	0	0	0
1585	A:A:K349	R:R:A307	1.61	No	No	0	5	5
1586	M:M:S21	M:M:T78	1.6	No	Yes	0	0	0
1587	M:M:S31	M:M:T28	1.6	Yes	No	0	0	0
1588	R:R:S71	R:R:T73	1.6	No	No	0	7	7
1589	B:B:S31	B:B:T34	1.6	No	Yes	0	1	5
1590	B:B:S207	B:B:T223	1.6	No	No	0	5	2
1591	B:B:S265	B:B:T249	1.6	No	Yes	0	2	6
1592	B:B:S265	B:B:T263	1.6	No	No	0	2	1
1593	L:L:T36	L:L:V30	1.59	No	No	0	0	0
1594	R:R:T168	R:R:V118	1.59	No	No	0	6	5
1595	R:R:C218	R:R:L132	1.59	Yes	No	0	6	6
1596	A:A:T187	A:A:V185	1.59	No	No	0	6	5
1597	R:R:A111	R:R:L108	1.58	No	No	0	4	5
1598	R:R:A237	R:R:L226	1.58	No	Yes	3	7	8
1599	A:A:L348	R:R:A237	1.58	Yes	No	3	9	7
1600	A:A:L353	R:R:A237	1.58	Yes	No	3	7	7
1601	R:R:A247	R:R:L301	1.58	No	Yes	0	6	7
1602	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
1603	L:L:T183	L:L:T185	1.57	No	No	0	0	0
1604	L:L:E200	L:L:P209	1.57	No	No	0	0	0
1605	M:M:T28	M:M:T30	1.57	No	No	0	0	0
1606	R:R:C274	R:R:N278	1.57	No	No	0	5	3
1607	B:B:T165	B:B:T181	1.57	No	Yes	0	7	2
1608	B:B:T179	B:B:T181	1.57	No	Yes	0	4	2
1609	M:M:A171	M:M:N168	1.56	No	No	0	0	0
1610	R:R:A98	R:R:N37	1.56	No	No	0	5	3
1611	A:A:N347	R:R:A137	1.56	No	No	0	8	8
1612	A:A:N347	R:R:A141	1.56	No	No	0	8	8
1613	R:R:I204	R:R:S260	1.55	No	No	0	5	5
1614	R:R:I221	R:R:S224	1.55	No	No	0	4	4
1615	R:R:I53	R:R:V54	1.54	No	No	0	5	4
1616	R:R:I213	R:R:V214	1.54	No	No	0	3	6
1617	A:A:A226	A:A:D229	1.54	No	No	0	8	8
1618	B:B:A28	B:B:D27	1.54	No	No	0	4	8
1619	B:B:A56	B:B:D76	1.54	No	Yes	0	7	9
1620	L:L:A158	L:L:Q160	1.52	No	No	0	0	0
1621	M:M:K23	M:M:V5	1.52	No	No	0	0	0
1622	R:R:I44	R:R:T43	1.52	No	No	0	5	4
1623	R:R:I47	R:R:T51	1.52	No	No	0	4	5
1624	R:R:K154	R:R:V155	1.52	No	No	0	3	2
1625	B:B:A26	B:B:Q259	1.52	No	No	0	3	6
1626	A:A:F354	R:R:G306	1.51	Yes	No	0	5	8
1627	A:A:A7	A:A:E8	1.51	No	No	0	1	5
1628	A:A:M198	A:A:T187	1.51	Yes	No	0	7	6
1629	A:A:F354	A:A:G352	1.51	Yes	No	0	5	8
1630	B:B:T34	G:G:M38	1.51	Yes	No	0	5	4
1631	R:R:L86	R:R:S119	1.5	No	No	0	7	8
1632	M:M:N210	M:M:S169	1.49	No	No	0	0	0
1633	M:M:L172	M:M:V176	1.49	Yes	No	9	0	0
1634	M:M:L172	M:M:V195	1.49	Yes	No	9	0	0
1635	M:M:L172	M:M:V197	1.49	Yes	No	0	0	0
1636	R:R:L150	R:R:V155	1.49	No	No	0	4	2
1637	R:R:L246	R:R:V242	1.49	No	No	0	5	4
1638	B:B:L168	B:B:V158	1.49	No	No	0	6	5
1639	A:A:V13	B:B:N88	1.48	No	No	0	3	7
1640	L:L:D75	L:L:S22	1.47	No	No	0	0	0
1641	R:R:C251	R:R:H294	1.47	No	Yes	0	8	9
1642	R:R:I265	R:R:I270	1.47	No	No	0	3	5
1643	R:R:L290	R:R:T287	1.47	No	Yes	0	7	6
1644	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
1645	R:R:A175	R:R:H113	1.46	No	Yes	0	4	6
1646	A:A:I19	A:A:M18	1.46	No	No	0	9	4
1647	A:A:D200	A:A:V185	1.46	No	No	0	9	5
1648	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1649	R:R:I39	R:R:K38	1.45	No	No	0	5	4
1650	A:A:D328	A:A:T329	1.45	No	No	0	9	9
1651	B:B:D170	B:B:T177	1.45	No	No	0	9	4
1652	R:R:I53	R:R:L85	1.43	No	No	0	5	7
1653	R:R:I60	R:R:L85	1.43	No	No	0	7	7
1654	R:R:I243	R:R:L301	1.43	No	Yes	0	5	7
1655	A:A:E238	A:A:V233	1.43	No	No	0	4	5
1656	B:B:I18	G:G:L19	1.43	Yes	No	0	7	9
1657	G:G:E58	G:G:V54	1.43	No	No	0	5	6
1658	R:R:G105	R:R:W102	1.41	No	Yes	0	8	9
1659	R:R:L210	R:R:M205	1.41	No	No	0	6	4
1660	A:A:K279	A:A:N294	1.4	No	No	0	2	3
1661	A:A:D237	A:A:M240	1.39	No	No	0	8	6
1662	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
1663	B:B:A299	B:B:F278	1.39	No	Yes	0	5	7
1664	L:L:A116	L:L:R113	1.38	No	Yes	0	0	0
1665	R:R:L301	R:R:L305	1.38	Yes	No	0	7	6
1666	A:A:D350	R:R:K308	1.38	No	No	0	4	6
1667	A:A:D26	A:A:K29	1.38	No	No	0	5	1
1668	A:A:D315	A:A:K314	1.38	No	No	0	3	3
1669	B:B:A11	B:B:R8	1.38	No	No	0	5	3
1670	B:B:D303	B:B:K301	1.38	No	Yes	0	2	5
1671	B:B:N35	B:B:N36	1.36	No	No	0	1	1
1672	A:A:E43	A:A:K270	1.35	No	No	0	9	9
1673	R:R:A164	R:R:Y121	1.33	No	Yes	0	7	7
1674	L:L:E218	L:L:N215	1.31	No	No	0	0	0
1675	R:R:H232	R:R:K236	1.31	No	No	0	4	8
1676	R:R:E275	R:R:N278	1.31	No	No	0	3	3
1677	A:A:H244	A:A:M240	1.31	No	No	0	4	6
1678	A:A:D309	A:A:Q306	1.31	No	No	0	4	5
1679	A:A:D237	A:A:E239	1.3	No	No	0	8	4
1680	M:M:R223	M:M:T208	1.29	No	No	0	0	0
1681	R:R:V177	R:R:Y184	1.26	Yes	No	0	4	5
1682	A:A:M18	A:A:R21	1.24	No	No	0	4	4
1683	A:A:K312	A:A:R313	1.24	No	Yes	0	5	4
1684	A:A:K317	A:A:R313	1.24	No	Yes	0	7	4
1685	R:R:F107	R:R:L108	1.22	No	No	0	1	5
1686	A:A:I285	A:A:Y230	1.21	No	Yes	0	3	8
1687	A:A:E28	A:A:R24	1.16	No	No	0	4	3
1688	B:B:E130	B:B:R129	1.16	Yes	No	0	3	3
1689	A:A:R15	B:B:H91	1.13	No	Yes	0	5	5
1690	A:A:E297	A:A:Y296	1.12	No	Yes	0	4	4
1691	B:B:R46	B:B:W339	1	No	Yes	0	5	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:M4	3.246	5	1	0
2	L:L:Q6	3.84167	6	1	0
3	L:L:C23	5.4075	4	1	0
4	L:L:Y37	6.824	5	1	0
5	L:L:W40	8.23571	7	1	0
6	L:L:F41	5.152	5	1	0
7	L:L:Q42	7.4325	4	1	0
8	L:L:P49	7.745	4	1	0
9	L:L:R51	5.97714	7	1	0
10	L:L:L52	4.852	5	1	0
11	L:L:I53	4.505	4	1	0
12	L:L:Y54	5.906	5	1	0
13	L:L:K55	4.774	5	1	0
14	L:L:V63	4.97	6	1	0
15	L:L:R66	8.015	6	1	0
16	L:L:F67	4.84571	7	1	0
17	L:L:I80	3.1575	4	1	0
18	L:L:D87	5.992	5	1	0
19	L:L:Y91	4.992	5	1	0
20	L:L:Y92	5.03	5	1	0
21	L:L:M94	7.984	5	1	0
22	L:L:Q95	4.42	5	1	0
23	L:L:W99	7.06	5	1	0
24	L:L:L101	4.72667	6	1	0
25	L:L:F103	8.1875	4	1	0
26	L:L:G106	2.8925	4	1	0
27	L:L:E110	4.4475	4	7	0
28	L:L:R113	4.08667	6	16	0
29	L:L:P118	7.035	4	7	0
30	L:L:F121	3.74	4	0	0
31	L:L:I122	3.6675	4	7	0
32	L:L:F123	4.996	5	0	0
33	L:L:P124	3.345	4	19	0
34	L:L:E128	8.898	5	14	0
35	L:L:V137	3.88	4	7	0
36	L:L:C139	3.485	6	7	0
37	L:L:F144	3.06167	6	7	0
38	L:L:P146	5.5025	4	0	0
39	L:L:V151	3.506	5	7	0
40	L:L:W153	7.84167	6	7	0
41	L:L:D175	2.675	4	16	0
42	L:L:T177	5.985	4	16	0
43	L:L:Y178	7.665	4	7	0
44	L:L:L180	3.2875	4	7	0
45	L:L:L184	8.025	4	7	0
46	L:L:Y191	5.86167	6	12	0
47	L:L:H194	9.635	4	12	0
48	L:L:Y197	8.482	5	12	0
49	L:L:C199	3.838	5	7	0
50	L:L:V201	3.72	6	7	0
51	L:L:H203	5.84	5	7	0
52	L:L:F214	5.3625	4	0	0
53	L:L:R216	5.8825	4	12	0
54	M:M:L4	4.118	5	1	0
55	M:M:Q6	4.672	5	1	0
56	M:M:V18	4.805	4	1	0
57	M:M:C22	4.425	4	1	0
58	M:M:Y27	4.105	6	1	0
59	M:M:F29	4.482	5	1	0
60	M:M:S31	3.795	4	1	0
61	M:M:Y32	6.33667	6	1	0
62	M:M:W36	7.22286	7	1	0
63	M:M:R38	8.6575	4	1	0
64	M:M:Q39	6.9725	4	1	0
65	M:M:W47	5.7	6	0	0
66	M:M:W50	5.53833	6	1	0
67	M:M:S52	2.982	5	1	0
68	M:M:T53	3.945	4	1	0
69	M:M:N55	8.9175	4	1	0
70	M:M:Y60	9.0425	4	0	0
71	M:M:R67	5.39	5	0	0
72	M:M:V68	5.0575	4	0	0
73	M:M:M70	5.358	5	1	0
74	M:M:T78	5.265	4	0	0
75	M:M:M81	7.685	4	1	0
76	M:M:L83	3.476	5	1	0
77	M:M:L86	4.9625	4	1	0
78	M:M:Y94	4.81	6	1	0
79	M:M:Y95	5.375	6	1	0
80	M:M:R98	7.9375	4	1	0
81	M:M:H99	6.356	5	1	0
82	M:M:I101	4.13	4	1	0
83	M:M:Y107	3.864	5	1	0
84	M:M:Y108	5.61	6	1	0
85	M:M:Y111	6.76833	6	1	0
86	M:M:M113	5.076	5	1	0
87	M:M:W116	6.625	6	1	0
88	M:M:T129	3.75	4	9	0
89	M:M:P132	5.168	5	9	0
90	M:M:V134	4.498	5	9	0
91	M:M:F135	9.9375	4	14	0
92	M:M:P139	2.455	4	0	0
93	M:M:L151	4.2825	4	0	0
94	M:M:C153	4.0825	4	9	0
95	M:M:Y158	5.20167	6	9	0
96	M:M:P160	6.652	5	9	0
97	M:M:W167	6.188	5	9	0
98	M:M:L172	1.8675	4	9	0
99	M:M:F179	4.8875	4	20	0
100	M:M:L188	4.0475	4	0	0
101	M:M:Y207	4.956	5	0	0
102	M:M:H213	6.45	7	9	0
103	M:M:P215	6.185	4	9	0
104	R:R:P27	5.6175	4	1	5
105	R:R:F29	8.314	5	1	4
106	R:R:F49	3.688	5	0	6
107	R:R:M63	3.685	4	17	6
108	R:R:D74	5.68	4	17	8
109	R:R:Y76	4.814	5	3	7
110	R:R:H79	7.805	4	3	9
111	R:R:L80	5.195	4	5	9
112	R:R:D84	5.27167	6	5	9
113	R:R:F87	6.474	5	5	7
114	R:R:W94	4.885	4	0	7
115	R:R:W102	6.81714	7	5	9
116	R:R:F104	8.3525	4	0	7
117	R:R:H113	5.296	5	5	6
118	R:R:L120	3.31	4	5	7
119	R:R:Y121	4.26667	6	5	7
120	R:R:I126	3.9775	4	0	7
121	R:R:F129	3.1625	4	3	5
122	R:R:I130	4.72	4	3	8
123	R:R:R134	5.942	5	3	9
124	R:R:Y135	5.772	5	23	8
125	R:R:L136	2.655	4	0	5
126	R:R:R148	8.3825	4	3	6
127	R:R:V156	5.175	4	3	5
128	R:R:W161	7.8725	4	3	9
129	R:R:F174	6.168	5	5	4
130	R:R:V177	3.26	4	5	4
131	R:R:S178	4.1975	4	1	1
132	R:R:R183	3.76	4	0	3
133	R:R:I185	3.61	5	1	3
134	R:R:D187	4.3275	4	0	3
135	R:R:R188	7.09	5	5	5
136	R:R:F189	4.194	5	1	3
137	R:R:Y190	7.98	6	5	4
138	R:R:W195	4.1425	4	5	5
139	R:R:F199	5.53333	6	5	5
140	R:R:Q200	5.5775	4	0	5
141	R:R:Q202	4.99	4	5	3
142	R:R:H203	6.41	4	5	4
143	R:R:P211	2.58	4	0	9
144	R:R:C218	2.842	5	0	6
145	R:R:Y219	4.796	5	0	8
146	R:R:L226	3.555	4	3	8
147	R:R:K234	6.93	4	3	7
148	R:R:F248	5.052	5	0	9
149	R:R:F249	4.6875	4	0	4
150	R:R:W252	5.21167	6	5	9
151	R:R:Y255	4.83857	7	5	7
152	R:R:Y256	6.6	6	5	8
153	R:R:D262	5.5675	4	0	5
154	R:R:T287	3.08	4	0	6
155	R:R:F292	5.45	5	5	7
156	R:R:H294	5.30167	6	5	9
157	R:R:C295	2.825	4	5	9
158	R:R:L301	2.454	5	3	7
159	R:R:Y302	4.076	5	3	9
160	R:R:F309	6.026	5	17	8
161	A:A:V34	4.42	4	3	5
162	A:A:I49	3.3025	4	3	7
163	A:A:I184	2.9025	4	2	9
164	A:A:F189	4.376	5	3	9
165	A:A:F191	4.74	5	3	5
166	A:A:F196	5.898	5	3	7
167	A:A:M198	4.428	5	3	7
168	A:A:F199	6.69167	6	2	5
169	A:A:V201	4.335	4	2	9
170	A:A:Q204	4.27	4	2	9
171	A:A:R208	2.918	5	2	9
172	A:A:K210	6.88	4	2	9
173	A:A:W211	3.48429	7	2	9
174	A:A:I212	3.35	4	2	8
175	A:A:F215	3.89	8	2	9
176	A:A:F223	4.89	5	4	9
177	A:A:L227	3.9775	4	4	7
178	A:A:Y230	4.31857	7	4	8
179	A:A:L232	5.29	4	4	8
180	A:A:F250	5.195	6	4	9
181	A:A:C254	4.072	5	4	5
182	A:A:W258	5.4375	8	2	5
183	A:A:F259	4.374	5	2	9
184	A:A:I265	2.818	5	3	8
185	A:A:L266	3.144	5	4	9
186	A:A:F267	3.32143	7	3	9
187	A:A:L268	4.364	5	4	8
188	A:A:F274	4.29333	6	4	9
189	A:A:C286	5.2875	4	4	6
190	A:A:Y287	5.89143	7	4	7
191	A:A:Y290	8.37	4	4	7
192	A:A:Y296	3.975	6	4	4
193	A:A:E298	7.5225	4	4	4
194	A:A:Y302	5.625	4	4	6
195	A:A:I303	4.476	5	4	7
196	A:A:F307	4.19333	6	4	8
197	A:A:R313	2.56	4	0	4
198	A:A:Y320	4.84571	7	3	7
199	A:A:T321	7.505	4	4	5
200	A:A:F323	3.814	5	4	4
201	A:A:F334	5.895	4	3	3
202	A:A:F336	3.94833	6	3	8
203	A:A:K345	4.07	5	3	5
204	A:A:L348	3.044	5	3	9
205	A:A:L353	4.015	4	3	7
206	A:A:F354	4.73333	6	0	5
207	B:B:I18	3.3625	4	0	7
208	B:B:L30	5.415	4	0	5
209	B:B:T34	3.0125	4	0	5
210	B:B:I37	3.555	4	10	2
211	B:B:V40	3.488	5	10	3
212	B:B:L51	5.85	5	6	9
213	B:B:H54	6.82143	7	6	9
214	B:B:Y59	6.728	5	2	8
215	B:B:W63	6.26167	6	6	7
216	B:B:R68	9.485	4	6	5
217	B:B:L69	3.388	5	6	5
218	B:B:L70	5.4275	4	6	5
219	B:B:V71	3.645	4	0	8
220	B:B:D76	6.6125	4	6	9
221	B:B:K78	5.3525	4	0	8
222	B:B:I80	6.02	4	6	8
223	B:B:I81	3.925	4	0	7
224	B:B:W82	8.09	7	6	9
225	B:B:S84	4.0375	4	6	5
226	B:B:K89	4.85333	6	6	9
227	B:B:H91	4.786	5	0	5
228	B:B:I93	4.954	5	13	7
229	B:B:L95	3.382	5	13	8
230	B:B:W99	5.71	8	2	9
231	B:B:Y105	3.59143	7	0	6
232	B:B:Y111	5.45667	6	2	4
233	B:B:A113	2.045	4	2	9
234	B:B:G115	2.39	4	0	9
235	B:B:L117	3.53	6	2	9
236	B:B:N119	4.1475	4	2	9
237	B:B:I120	3.305	4	0	6
238	B:B:Y124	4.54167	6	13	6
239	B:B:T128	6.3575	4	25	3
240	B:B:E130	5.995	4	25	3
241	B:B:H142	6.34333	6	2	9
242	B:B:Y145	3.8925	8	2	8
243	B:B:L146	3.872	5	2	7
244	B:B:C148	3.46	4	8	6
245	B:B:C149	2.44	5	2	8
246	B:B:R150	5.4275	4	8	6
247	B:B:F151	3.76286	7	2	9
248	B:B:T159	6.115	4	2	9
249	B:B:S160	3.554	5	8	6
250	B:B:S161	7.2575	4	2	9
251	B:B:D163	7.7375	4	2	9
252	B:B:C166	3.6975	4	8	8
253	B:B:W169	8.644	5	2	8
254	B:B:F180	5.844	5	8	7
255	B:B:T181	2.82	4	0	2
256	B:B:H183	5.55	7	8	9
257	B:B:D186	4.9	4	2	9
258	B:B:V187	4.685	4	8	9
259	B:B:L190	3.834	5	8	5
260	B:B:F199	5.76833	6	8	9
261	B:B:V200	5.5475	4	2	6
262	B:B:S201	3.6	4	8	9
263	B:B:C204	4.136	5	2	7
264	B:B:D205	6.4175	4	8	9
265	B:B:K209	8.2375	4	8	6
266	B:B:L210	4.5525	4	0	5
267	B:B:W211	6.80667	6	8	8
268	B:B:C218	4.4775	4	8	5
269	B:B:Q220	6.045	4	2	7
270	B:B:F222	5.874	5	2	8
271	B:B:H225	7.44571	7	2	9
272	B:B:I232	5.3375	4	2	8
273	B:B:F234	4.72	4	2	5
274	B:B:F235	5.60286	7	2	6
275	B:B:P236	5.3075	4	2	7
276	B:B:F241	4.93	7	2	6
277	B:B:T243	4.00833	6	2	8
278	B:B:G244	2.2875	4	2	5
279	B:B:D247	6.124	5	2	9
280	B:B:T249	4.51	4	2	6
281	B:B:C250	2.4075	4	2	8
282	B:B:R251	9.936	5	2	8
283	B:B:F253	4.932	5	2	6
284	B:B:D258	8.005	4	2	7
285	B:B:Y264	4.58333	6	2	5
286	B:B:I269	3.4675	4	2	4
287	B:B:I273	4.5575	4	2	6
288	B:B:F278	4.586	5	2	7
289	B:B:R283	7.832	5	10	9
290	B:B:L285	4.065	4	2	6
291	B:B:G288	1.8675	4	0	7
292	B:B:Y289	6.35833	6	2	7
293	B:B:D290	7.945	4	2	6
294	B:B:N295	6.74	4	2	6
295	B:B:W297	4.04667	6	2	8
296	B:B:K301	4.51	4	0	5
297	B:B:H311	7.834	5	11	9
298	B:B:R314	8.865	4	2	8
299	B:B:L318	2.735	6	6	6
300	B:B:T321	5.382	5	6	7
301	B:B:V327	3.2275	4	0	6
302	B:B:W332	8.04571	7	2	9
303	B:B:D333	6.8875	4	11	9
304	B:B:L336	3.845	4	6	7
305	B:B:K337	4.658	5	11	6
306	B:B:I338	3.0575	4	6	5
307	B:B:W339	6.41333	6	11	9
308	G:G:V16	3.226	5	15	7
309	G:G:R27	3.836	5	0	8
310	G:G:Y40	7.225	4	2	6
311	G:G:D48	6.205	6	10	9
312	G:G:P49	3.4525	4	0	7
313	G:G:L51	4.72167	6	10	6
314	G:G:P60	5.6375	4	6	9
315	G:G:F61	4.11625	8	6	8
316	W:W:?1	8.20625	8	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:Y92	M:M:I45	91.6297	3.63	Yes	No	1	0	0
2	L:L:F103	M:M:I45	91.721	11.3	Yes	No	1	0	0
3	L:L:F90	L:L:Y92	93.8172	9.28	No	Yes	0	0	0
4	L:L:F90	L:L:K108	93.7757	8.69	No	No	0	0	0
5	L:L:E110	L:L:K108	93.6927	4.05	Yes	No	0	0	0
6	L:L:F41	L:L:R51	92.5355	5.34	Yes	Yes	1	0	0
7	L:L:F103	L:L:F41	91.3794	5.36	Yes	Yes	1	0	0
8	L:L:R51	R:R:D181	95.3078	8.34	Yes	No	1	0	2
9	L:L:E110	L:L:Y178	92.3874	5.61	Yes	Yes	7	0	0
10	L:L:F144	L:L:Y178	92.1789	4.13	Yes	Yes	7	0	0
11	L:L:F144	L:L:L141	91.633	2.44	Yes	No	7	0	0
12	L:L:L141	L:L:V151	50.5983	4.47	No	Yes	7	0	0
13	L:L:C139	L:L:V151	20.4201	1.71	Yes	Yes	7	0	0
14	L:L:C139	L:L:I122	21.4554	3.27	Yes	Yes	7	0	0
15	L:L:F214	L:L:I122	42.4923	3.77	Yes	Yes	0	0	0
16	L:L:F214	L:L:Y197	41.6537	9.28	Yes	Yes	0	0	0
17	L:L:Y191	L:L:Y197	36.6228	15.89	Yes	Yes	12	0	0
18	L:L:L130	L:L:Y191	80.9704	2.34	No	Yes	0	0	0
19	L:L:K188	L:L:L130	80.4979	4.23	No	No	0	0	0
20	L:L:G133	L:L:K188	80.0254	3.49	No	No	0	0	0
21	L:L:G133	L:L:T134	79.5529	1.82	No	No	0	0	0
22	L:L:T134	M:M:K156	79.0804	4.5	No	No	0	0	0
23	M:M:K156	M:M:Q184	78.6078	9.49	No	No	0	0	0
24	M:M:Q184	M:M:S190	78.1352	8.66	No	No	0	0	0
25	M:M:S190	M:M:V182	77.6627	1.62	No	No	0	0	0
26	L:L:S167	M:M:V182	77.1901	3.23	No	No	0	0	0
27	L:L:S167	L:L:S181	76.7175	1.63	No	No	0	0	0
28	L:L:S181	M:M:F179	76.2449	6.61	No	Yes	0	0	0
29	L:L:L140	M:M:F179	74.3544	2.44	No	Yes	0	0	0
30	L:L:F121	L:L:L140	73.8817	6.09	Yes	No	0	0	0
31	L:L:L141	L:L:V201	40.9927	4.47	No	Yes	7	0	0
32	L:L:C139	L:L:V201	20.4897	1.71	Yes	Yes	7	0	0
33	L:L:C199	L:L:V151	20.4201	1.71	Yes	Yes	7	0	0
34	L:L:C199	L:L:I122	21.4553	3.27	Yes	Yes	7	0	0
35	L:L:C199	L:L:V201	20.4896	1.71	Yes	Yes	7	0	0
36	L:L:C139	L:L:W153	19.3518	5.22	Yes	Yes	7	0	0
37	L:L:V137	L:L:W153	46.2633	4.9	Yes	Yes	7	0	0
38	L:L:P125	L:L:V137	46.0076	3.53	No	Yes	0	0	0
39	L:L:P125	L:L:Y191	45.7489	5.56	No	Yes	0	0	0
40	L:L:C199	L:L:W153	19.3518	5.22	Yes	Yes	7	0	0
41	L:L:F121	L:L:F123	71.9909	2.14	Yes	Yes	0	0	0
42	L:L:F123	M:M:L137	29.3673	13.4	Yes	No	0	0	0
43	L:L:F123	M:M:P139	39.3143	2.89	Yes	Yes	0	0	0
44	M:M:L151	M:M:P139	37.8951	3.28	Yes	Yes	0	0	0
45	M:M:L151	M:M:V224	29.8438	7.45	Yes	No	0	0	0
46	M:M:G152	M:M:L137	28.8942	1.71	No	No	0	0	0
47	M:M:G152	M:M:W167	28.421	2.81	No	Yes	0	0	0
48	M:M:C153	M:M:W167	23.69	3.92	Yes	Yes	9	0	0
49	M:M:C153	M:M:V134	46.4276	3.42	Yes	Yes	9	0	0
50	M:M:V134	M:M:V155	43.5896	4.81	Yes	No	9	0	0
51	M:M:P132	M:M:V155	21.7949	1.77	Yes	No	9	0	0
52	M:M:H213	M:M:P132	13.2666	13.73	Yes	Yes	9	0	0
53	M:M:H213	M:M:P160	15.1626	3.05	Yes	Yes	9	0	0
54	M:M:C153	M:M:V224	23.6855	1.71	Yes	No	0	0	0
55	M:M:V155	M:M:Y158	20.8473	5.05	No	Yes	9	0	0
56	M:M:H213	M:M:Y158	13.2674	2.18	Yes	Yes	9	0	0
57	M:M:Y111	R:R:D181	95.3956	6.9	Yes	No	1	0	2
58	M:M:Y108	R:R:R30	100	3.09	Yes	No	0	0	5
59	R:R:H281	R:R:R30	100	12.41	No	No	0	4	5
60	R:R:D262	R:R:H281	100	10.08	Yes	No	0	5	4
61	R:R:D262	R:R:Q200	100	3.92	Yes	Yes	0	5	5
62	R:R:I259	R:R:Q200	100	6.86	No	Yes	0	5	5
63	R:R:I259	R:R:Y255	100	10.88	No	Yes	0	5	7
64	R:R:W252	R:R:Y255	100	2.89	Yes	Yes	5	9	7
65	B:B:G288	B:B:T274	17.0052	1.82	Yes	No	0	7	8
66	B:B:R314	B:B:T274	17.0603	2.59	Yes	No	2	8	8
67	A:A:W258	B:B:R314	40.3495	3	Yes	Yes	2	5	8
68	A:A:I212	A:A:W258	41.9568	2.35	Yes	Yes	2	8	5
69	A:A:I212	A:A:R208	42.2091	3.76	Yes	Yes	2	8	9
70	A:A:I253	A:A:R208	92.6507	3.76	No	Yes	0	8	9
71	A:A:I253	A:A:L39	92.7457	4.28	No	No	0	8	9
72	A:A:G40	A:A:L39	100	1.71	No	No	0	9	9
73	A:A:G40	A:A:G45	100	2.11	No	No	0	9	9
74	A:A:C224	A:A:G45	100	3.92	No	No	0	7	9
75	A:A:C224	A:A:I49	100	3.27	No	Yes	0	7	7
76	A:A:I49	A:A:L38	100	4.28	Yes	No	3	7	8
77	A:A:I222	A:A:L38	100	5.71	No	No	3	7	8
78	A:A:I222	A:A:I265	84.799	2.94	No	Yes	3	7	8
79	A:A:F334	A:A:I265	42.4689	2.51	Yes	Yes	3	3	8
80	A:A:F334	A:A:Y320	85.3868	3.09	Yes	Yes	3	3	7
81	A:A:D341	A:A:Y320	63.7375	5.75	No	Yes	3	8	7
82	A:A:D341	R:R:K234	63.7325	5.53	No	Yes	3	8	7
83	R:R:K234	R:R:L226	100	5.64	Yes	Yes	3	7	8
84	R:R:I222	R:R:L226	100	2.85	No	Yes	0	8	8
85	R:R:I222	R:R:Y219	100	2.42	No	Yes	0	8	8
86	R:R:I215	R:R:Y219	100	2.42	No	Yes	0	7	8
87	R:R:F248	R:R:I215	100	7.54	Yes	No	0	9	7
88	R:R:F248	R:R:W252	100	3.01	Yes	Yes	0	9	9
89	A:A:F267	A:A:I222	42.4967	2.51	Yes	No	3	9	7
90	A:A:F267	A:A:F334	42.8564	2.14	Yes	Yes	3	9	3
91	A:A:A338	A:A:I265	42.469	3.25	No	Yes	0	6	8
92	A:A:A338	A:A:Y320	42.4997	4	No	Yes	0	6	7
93	A:A:K345	A:A:Y320	64.1847	2.39	Yes	Yes	3	5	7
94	A:A:K345	R:R:K234	63.7676	4.31	Yes	Yes	3	5	7
95	R:R:H203	R:R:Y121	14.1321	7.62	Yes	Yes	5	4	7
96	B:B:L79	B:B:L95	12.1873	2.77	No	Yes	0	7	8
97	B:B:G77	B:B:L95	23.2508	1.71	No	Yes	0	8	8
98	B:B:G77	B:B:S98	23.4506	1.86	No	No	0	8	8
99	B:B:S98	B:B:W99	23.6514	6.18	No	Yes	0	8	9
100	A:A:F215	B:B:W99	12.6038	4.01	Yes	Yes	2	9	9
101	A:A:F215	A:A:W211	14.3289	4.01	Yes	Yes	2	9	9
102	A:A:R208	A:A:W211	52.1822	2	Yes	Yes	2	9	9
103	B:B:L95	B:B:Y124	10.7724	4.69	Yes	Yes	13	8	6
104	B:B:L117	B:B:W99	12.6346	4.56	Yes	Yes	2	9	9
105	A:A:W211	B:B:L117	17.5524	2.28	Yes	Yes	2	9	9
106	A:A:F223	A:A:L39	34.6329	2.44	Yes	No	0	9	9
107	A:A:W211	B:B:Y145	18.7306	1.93	Yes	Yes	2	9	8
108	A:A:F223	A:A:V225	12.0745	2.62	Yes	No	0	9	7
109	A:A:F223	A:A:F250	10.939	9.65	Yes	Yes	4	9	9
110	A:A:F223	A:A:L266	12.3874	3.65	Yes	Yes	4	9	9
111	A:A:F307	A:A:I303	11.5473	2.51	Yes	Yes	4	8	7
112	B:B:G244	B:B:T243	14.1729	1.82	Yes	Yes	2	5	8
113	B:B:G244	B:B:I273	14.3944	3.53	Yes	Yes	2	5	6
114	B:B:G272	B:B:I273	16.9814	1.76	No	Yes	0	4	6
115	B:B:D290	B:B:G272	17.0827	3.35	Yes	No	0	6	4
116	B:B:D290	B:B:R314	23.2531	17.87	Yes	Yes	2	6	8
117	M:M:Y108	M:M:Y111	95.1932	1.99	Yes	Yes	1	0	0

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:D33	R:R:E32	5.2	0	No	No	0	4	0	1
L:L:R51	R:R:D181	8.34	1	Yes	No	0	2	0	1
L:L:Y54	R:R:D182	2.3	1	Yes	No	0	6	0	1
L:L:K55	R:R:D182	8.3	1	Yes	No	0	6	0	1
L:L:W99	R:R:F29	4.01	1	Yes	Yes	0	4	0	1
M:M:S31	R:R:S178	3.26	1	Yes	Yes	0	1	0	1
M:M:S31	R:R:F189	3.96	1	Yes	Yes	0	3	0	1
M:M:Y32	R:R:S178	3.82	1	Yes	Yes	0	1	0	1
M:M:Y32	R:R:A180	2.67	1	Yes	No	0	1	0	1
M:M:W50	R:R:P27	5.4	1	Yes	Yes	0	5	0	1
M:M:W50	R:R:F29	7.02	1	Yes	Yes	0	4	0	1
M:M:Y54	R:R:D193	6.9	1	No	No	0	1	0	1
M:M:N55	R:R:D193	14.81	1	Yes	No	0	1	0	1
M:M:R58	R:R:M24	7.44	0	No	No	0	2	0	1
M:M:N59	R:R:E26	3.94	1	No	No	0	2	0	1
M:M:N59	R:R:P27	8.15	1	No	Yes	0	5	0	1
M:M:I101	R:R:I185	4.42	1	Yes	Yes	0	3	0	1
M:M:G103	R:R:F189	3.01	0	No	Yes	0	3	0	1
M:M:A104	R:R:D187	4.63	0	No	Yes	0	3	0	1
M:M:A104	R:R:Y190	2.67	0	No	Yes	0	4	0	1
M:M:R105	R:R:R30	2.13	0	No	No	0	5	0	1
M:M:R105	R:R:D187	3.57	0	No	Yes	0	3	0	1
M:M:N106	R:R:I185	4.25	0	No	Yes	0	3	0	1
M:M:N106	R:R:D187	6.73	0	No	Yes	0	3	0	1
M:M:Y107	R:R:F29	4.13	1	Yes	Yes	0	4	0	1
M:M:Y108	R:R:R30	3.09	1	Yes	No	0	5	0	1
M:M:Y108	R:R:E32	3.37	1	Yes	No	0	4	0	1
M:M:Y109	R:R:F29	20.63	1	No	Yes	0	4	0	1
M:M:Y111	R:R:A180	5.34	1	Yes	No	0	1	0	1
M:M:Y111	R:R:D181	6.9	1	Yes	No	0	2	0	1
M:M:Y111	R:R:R183	4.12	1	Yes	Yes	0	3	0	1
M:M:G112	R:R:D181	3.35	1	No	No	0	2	0	1
R:R:E26	R:R:K25	2.7	1	No	No	2	4	1	2
R:R:E26	R:R:P27	3.14	1	No	Yes	2	5	1	1
R:R:F29	R:R:P27	5.78	1	Yes	Yes	4	5	1	1
R:R:H281	R:R:R30	12.41	0	No	No	4	5	2	1
R:R:E32	R:R:N37	2.63	0	No	No	4	3	1	2
R:R:D97	R:R:R183	2.38	0	No	Yes	5	3	2	1
R:R:N101	R:R:R183	6.03	22	No	Yes	4	3	2	1
R:R:F174	R:R:Y190	9.28	5	Yes	Yes	4	4	2	1
R:R:F174	R:R:F199	3.22	5	Yes	Yes	4	5	2	2
R:R:F189	R:R:N176	3.62	1	Yes	No	3	4	1	2
R:R:I185	R:R:S178	3.1	1	Yes	Yes	3	1	1	1
R:R:F189	R:R:S178	6.61	1	Yes	Yes	3	1	1	1
R:R:I185	R:R:R183	2.51	1	Yes	Yes	3	3	1	1
R:R:F189	R:R:I185	3.77	1	Yes	Yes	3	3	1	1
R:R:D187	R:R:R188	2.38	0	Yes	Yes	3	5	1	2
R:R:R188	R:R:Y190	13.38	5	Yes	Yes	5	4	2	1
R:R:F199	R:R:R188	2.14	5	Yes	Yes	5	5	2	2
R:R:W195	R:R:Y190	3.86	5	Yes	Yes	5	4	2	1
R:R:V196	R:R:Y190	6.31	0	No	Yes	4	4	2	1
R:R:F199	R:R:Y190	12.38	5	Yes	Yes	5	4	2	1
R:R:F199	R:R:W195	3.01	5	Yes	Yes	5	5	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
55.56	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
30.77	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
27.78	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
27.78	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
26.67	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
26.67	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
25.00	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
25.00	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
25.00	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
25.00	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
25.00	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
25.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
25.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
25.00	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
23.53	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
23.08	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
23.08	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
23.08	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
23.08	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
23.08	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
23.08	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
22.73	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
22.22	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
22.22	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
22.22	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
22.22	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
21.43	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
21.43	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
21.43	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
21.43	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
21.43	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
21.43	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
21.05	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
21.05	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
20.83	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
20.00	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
20.00	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
20.00	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
20.00	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
20.00	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
20.00	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
20.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
20.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
20.00	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
19.05	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
19.05	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
18.75	Single	5V56	TC114	5V56-SMO-TC114
18.75	Single	5V57	TC114	5V57-SMO-TC114
18.75	Single	6OS1	TRV026	6OS1-AT₁-TRV026
18.75	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
18.75	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
18.75	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
18.75	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
18.75	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
18.18	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
18.18	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
18.18	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
18.18	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
18.18	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
18.18	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
18.18	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
18.18	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
18.18	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
18.18	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
18.18	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
18.18	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
17.86	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
17.65	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
17.65	Single	6OS2	TRV026	6OS2-AT₁-TRV026
17.65	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
17.65	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
17.65	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.65	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
17.65	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
17.65	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
17.65	Consensus	dp_off	Orthosteric Ligand	dp2_off
17.65	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
17.65	Consensus	nts_on	Orthosteric Ligand	nts1_on
17.65	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
17.39	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
17.39	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
16.67	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
16.67	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
16.67	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
16.67	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
16.67	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
16.67	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
16.67	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
16.67	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
16.67	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
16.67	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
16.67	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
16.67	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
16.67	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
16.67	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
16.67	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
16.67	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
16.67	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
16.67	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
16.67	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
16.67	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
16.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
16.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
16.67	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
16.67	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
16.67	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
16.67	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
16.67	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
16.67	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
16.67	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
16.67	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
16.67	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
16.67	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
16.67	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
16.67	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
16.67	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
16.67	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
16.67	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
16.67	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
16.67	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
16.67	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
16.67	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
16.67	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
16.67	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	7FII	hCG	7FII-LH-hCG-6fuf
16.67	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
16.67	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
16.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
16.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
16.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
16.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
16.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
16.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
16.67	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
16.67	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
16.67	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
16.67	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
16.67	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
16.67	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
16.67	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
16.67	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
16.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
16.67	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
16.67	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
16.67	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
16.67	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
16.67	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
16.67	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
16.67	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
16.67	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
16.67	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
16.67	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
16.67	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
16.67	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
16.67	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
16.67	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
16.67	Single	7XW7	K1-70	7XW7-TSH-K1-70
16.67	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
16.67	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
16.67	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
16.67	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
16.67	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
16.67	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
16.67	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
16.67	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
16.67	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
16.67	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
16.67	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
16.67	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
16.67	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
16.67	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
16.67	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
16.67	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
16.67	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
16.67	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
16.67	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
16.67	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
16.67	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
16.67	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
16.67	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
16.67	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
16.67	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
16.67	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
16.67	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
16.67	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
16.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
16.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
16.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
16.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
16.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
16.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
16.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
16.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
16.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
16.67	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
16.67	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
16.67	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
16.67	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
16.67	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
16.67	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
16.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
16.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
16.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
16.67	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
16.67	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
16.67	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
16.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
16.67	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
16.67	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
16.67	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
16.67	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
16.67	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
16.67	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
16.67	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
16.67	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
16.67	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
16.67	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
16.67	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
16.67	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
16.67	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
16.67	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
16.67	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
16.67	Consensus	go_protein	Orthosteric Ligand	go_chemokine
16.67	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
16.67	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
16.67	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
16.67	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
16.67	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
16.67	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
16.67	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
16.67	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
16.67	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
16.67	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
16.67	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
16.67	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
16.67	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
16.67	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
16.67	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
16.67	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
16.67	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
16.67	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
16.67	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
16.67	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
16.67	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
16.67	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
16.00	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
15.79	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
15.79	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.79	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
15.79	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.79	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.38	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
15.38	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
15.38	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
15.38	Single	5U09	Taranabant	5U09-CB₁-Taranabant
15.38	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
15.38	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
15.38	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
15.38	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
15.38	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
15.38	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
15.38	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
15.38	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
15.38	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
15.38	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
15.38	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
15.38	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
15.38	Consensus	class-f_off	Orthosteric Ligand	smo_off
15.38	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
15.38	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
15.38	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
15.38	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
15.38	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
15.00	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
15.00	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
15.00	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
15.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
15.00	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
15.00	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
14.29	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
14.29	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
14.29	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
14.29	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
14.29	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
14.29	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
14.29	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
14.29	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
14.29	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
14.29	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
14.29	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
14.29	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
14.29	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
14.29	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
14.29	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
14.29	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
14.29	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
14.29	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
14.29	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
14.29	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
14.29	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
14.29	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
14.29	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
14.29	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
14.29	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
14.29	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
14.29	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
14.29	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
14.29	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
14.29	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
14.29	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
14.29	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
14.29	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
14.29	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
14.29	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
14.29	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
14.29	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
14.29	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
14.29	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
14.29	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
14.29	Consensus	hcar_on	Orthosteric Ligand	hca_on
14.29	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
13.64	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
13.64	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
13.64	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
13.64	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
13.64	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
13.64	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
13.64	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
13.64	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
13.64	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
13.64	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.64	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.64	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
13.33	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
13.33	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
13.33	Single	6D27	CAY10471	6D27-DP₂-CAY10471
13.33	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
13.33	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
13.33	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
13.33	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
13.33	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
13.33	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
13.33	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.33	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.33	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
13.33	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
13.33	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
13.33	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
13.33	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
13.33	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
13.33	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
13.33	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
13.33	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
13.33	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
13.33	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
13.33	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
13.33	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
13.33	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
13.04	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
13.04	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
13.04	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
13.04	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
13.04	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
13.04	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
13.04	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
13.04	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
13.04	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
12.50	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
12.50	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
12.50	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
12.50	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
12.50	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
12.50	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
12.50	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.50	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
12.50	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
12.50	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
12.50	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
12.50	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
12.50	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
12.50	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
12.50	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
12.50	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
12.50	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
12.50	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
12.50	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
12.50	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.50	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
12.50	Single	8HS2	Fab046	8HS2-GPR20-Fab046
12.50	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
12.50	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
12.50	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
12.50	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
12.50	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
12.50	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
12.50	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
12.00	Single	6FJ3	PTH	6FJ3-PTH1-PTH
12.00	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
12.00	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
12.00	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
12.00	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
12.00	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
11.76	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
11.76	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
11.76	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
11.76	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
11.76	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
11.76	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
11.76	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
11.76	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
11.76	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
11.76	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.76	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
11.76	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
11.76	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.76	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
11.76	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
11.76	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
11.76	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
11.76	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
11.76	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
11.76	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
11.76	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
11.76	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
11.76	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
11.76	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
11.76	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
11.76	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
11.76	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
11.54	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
11.54	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
11.54	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
11.54	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
11.54	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
11.54	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
11.11	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
11.11	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
11.11	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
11.11	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
11.11	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
11.11	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
11.11	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
11.11	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
11.11	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.11	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
11.11	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
11.11	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
11.11	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
11.11	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
11.11	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
11.11	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.11	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
11.11	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
11.11	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
11.11	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.11	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.11	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
11.11	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
11.11	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
11.11	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
11.11	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
11.11	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
11.11	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
11.11	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
11.11	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
11.11	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
11.11	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
11.11	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.11	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
11.11	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
11.11	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
11.11	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
11.11	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
11.11	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
11.11	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
11.11	Consensus	gi_class-f	Other Ligand	gi_frizzled
11.11	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.11	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
11.11	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
11.11	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.11	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
11.11	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
11.11	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
10.71	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
10.71	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
10.71	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
10.71	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
10.71	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
10.53	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
10.53	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
10.53	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
10.53	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
10.53	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
10.53	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
10.53	Single	7EZC	UKA	7EZC-A_2A-UKA
10.53	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
10.53	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
10.53	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
10.53	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
10.53	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
10.53	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
10.53	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
10.53	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.53	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
10.53	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
10.53	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
10.53	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.53	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
10.53	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.53	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
10.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
10.00	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
10.00	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
10.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
10.00	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
10.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
10.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
10.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
10.00	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
10.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
10.00	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
10.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
10.00	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
10.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
10.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
10.00	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
10.00	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
10.00	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
10.00	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
10.00	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
10.00	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
10.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
10.00	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
10.00	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
10.00	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
9.68	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
9.68	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
9.68	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
9.68	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
9.52	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
9.52	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
9.52	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
9.52	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
9.52	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.52	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
9.52	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
9.52	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
9.52	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
9.52	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
9.52	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
9.52	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
9.52	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
9.52	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
9.52	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
9.52	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
9.52	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
9.52	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
9.38	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
9.38	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
9.09	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
9.09	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
9.09	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
9.09	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
9.09	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
9.09	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
9.09	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
9.09	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
9.09	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
9.09	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
9.09	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
9.09	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
9.09	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
9.09	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
9.09	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
9.09	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
9.09	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
8.70	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
8.70	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
8.70	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
8.70	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
8.70	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.70	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
8.70	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
8.70	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
8.70	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
8.70	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
8.70	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
8.33	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
8.33	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
8.33	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
8.33	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
8.33	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
8.33	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
8.33	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
8.33	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
8.33	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
8.33	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
8.33	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
8.33	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
8.33	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
8.33	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
8.33	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
8.33	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
8.33	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.33	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
8.33	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
8.33	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
8.33	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
8.33	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
8.33	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.33	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
8.33	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
8.33	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
8.33	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
8.33	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
8.33	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
8.33	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
8.33	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
8.33	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
8.33	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.33	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
8.33	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
8.00	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
8.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
8.00	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
8.00	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
8.00	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
8.00	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
8.00	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
8.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
8.00	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
8.00	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
8.00	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.00	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
8.00	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.00	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.00	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
7.69	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
7.69	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
7.69	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
7.69	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
7.69	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
7.69	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
7.69	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
7.69	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
7.69	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
7.69	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
7.69	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
7.69	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
7.69	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
7.69	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
7.69	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
7.69	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
7.69	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
7.69	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
7.69	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
7.69	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
7.69	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.69	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
7.69	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
7.69	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
7.69	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
7.69	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
7.69	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
7.69	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
7.69	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
7.69	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
7.69	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
7.69	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
7.69	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
7.69	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
7.69	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
7.69	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
7.69	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
7.41	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
7.41	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
7.41	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
7.41	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
7.41	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.41	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
7.41	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
7.41	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
7.41	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
7.41	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
7.41	Consensus	go_class-b1	Orthosteric Ligand	go_crf
7.41	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
7.41	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
7.14	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
7.14	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
7.14	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
7.14	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
7.14	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
7.14	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
7.14	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
7.14	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
7.14	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
7.14	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
7.14	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
7.14	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
7.14	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
7.14	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
7.14	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
7.14	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
7.14	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
7.14	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
7.14	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
7.14	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
7.14	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
7.14	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
7.14	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
7.14	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
7.14	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
7.14	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
7.14	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
7.14	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
7.14	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
7.14	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
7.14	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
7.14	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
7.14	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
7.14	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
7.14	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
7.14	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
7.14	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
7.14	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
7.14	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
7.14	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
7.14	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
7.14	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
7.14	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
7.14	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
7.14	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
7.14	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
7.14	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
7.14	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
7.14	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
7.14	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
7.14	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
6.90	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
6.90	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
6.90	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
6.90	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
6.90	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
6.67	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
6.67	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
6.67	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
6.67	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
6.67	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
6.67	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
6.67	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
6.67	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
6.67	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
6.67	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
6.67	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
6.67	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
6.67	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
6.67	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
6.67	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
6.67	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
6.67	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
6.67	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
6.67	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
6.67	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
6.67	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
6.67	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
6.67	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
6.67	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
6.67	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
6.67	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
6.67	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
6.67	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
6.67	Single	7T32	ZM241385	7T32-A_2A-ZM241385
6.67	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
6.67	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
6.67	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
6.67	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
6.67	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
6.67	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
6.67	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
6.67	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
6.67	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
6.67	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
6.67	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
6.67	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
6.67	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
6.67	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
6.67	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
6.67	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
6.67	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
6.67	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
6.67	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
6.67	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
6.67	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
6.67	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
6.67	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
6.67	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
6.67	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
6.67	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
6.67	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
6.67	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
6.67	Consensus	sensory_off	Orthosteric Ligand	opsin_off
6.45	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
6.45	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
6.45	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
6.45	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
6.45	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
6.45	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
6.25	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
6.25	Single	3EML	ZM241385	3EML-A_2A-ZM241385
6.25	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
6.25	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
6.25	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
6.25	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
6.25	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
6.25	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
6.25	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
6.25	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
6.25	Single	5UEN	DU172	5UEN-A₁-DU172
6.25	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
6.25	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
6.25	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
6.25	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
6.25	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
6.25	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
6.25	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
6.25	Single	6IIV	Daltroban	6IIV-TP-Daltroban
6.25	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
6.25	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
6.25	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
6.25	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
6.25	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
6.25	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
6.25	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
6.25	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
6.25	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
6.25	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.25	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
6.25	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
6.25	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
6.25	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
6.25	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
6.25	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
6.25	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
6.25	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
6.25	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
6.25	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
6.25	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
6.25	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
6.25	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
6.25	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
6.25	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
6.25	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
6.25	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
6.25	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
6.25	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
6.25	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
6.25	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
6.25	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
6.25	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
6.25	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
6.25	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
6.25	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
6.25	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
6.25	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
6.25	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
6.25	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
6.25	Consensus	a2_off	Orthosteric Ligand	a2a_off
6.25	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
6.25	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
6.25	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
6.25	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
6.25	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
6.25	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
6.25	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
6.25	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
6.25	Consensus	tar_on	Orthosteric Ligand	ta1_on
6.25	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
6.06	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
6.06	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
5.88	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
5.88	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
5.88	Single	5C1M	BU72	5C1M-μ-BU72
5.88	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
5.88	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
5.88	Single	5N2S	PSB36	5N2S-A₁-PSB36
5.88	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
5.88	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
5.88	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
5.88	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
5.88	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
5.88	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
5.88	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
5.88	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
5.88	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
5.88	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
5.88	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
5.88	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
5.88	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
5.88	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
5.88	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.88	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
5.88	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
5.88	Single	7C4S	S1P	7C4S-S1P₃-S1P
5.88	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
5.88	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
5.88	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
5.88	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
5.88	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
5.88	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
5.88	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
5.88	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
5.88	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
5.88	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
5.88	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
5.88	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
5.88	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
5.88	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
5.88	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
5.88	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
5.88	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
5.88	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
5.88	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
5.88	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
5.88	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
5.88	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
5.88	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
5.88	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
5.88	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
5.88	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
5.88	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
5.88	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
5.88	Consensus	ep_off	Orthosteric Ligand	ep4_off
5.88	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
5.88	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
5.71	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
5.71	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
5.71	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
5.56	Single	2YDV	NECA	2YDV-A_2A-NECA
5.56	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
5.56	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
5.56	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
5.56	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
5.56	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
5.56	Single	5G53	NECA	5G53-A_2A-NECA-Gs
5.56	Single	5XR8	AM841	5XR8-CB₁-AM841
5.56	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.56	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
5.56	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
5.56	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
5.56	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.56	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
5.56	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
5.56	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
5.56	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
5.56	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
5.56	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
5.56	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
5.56	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
5.56	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
5.56	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
5.56	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
5.56	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
5.56	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.56	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
5.56	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
5.56	Single	7W41	PD176252	7W41-BB₂-PD176252
5.56	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
5.56	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
5.56	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.56	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
5.56	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
5.56	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
5.56	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.56	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
5.56	Single	8E0G	BU72	8E0G-μ-BU72
5.56	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
5.56	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
5.56	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.56	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
5.56	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
5.56	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
5.56	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
5.56	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
5.56	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
5.56	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
5.56	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
5.56	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
5.56	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
5.56	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
5.56	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
5.56	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
5.56	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
5.56	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
5.56	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
5.56	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
5.56	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
5.56	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
5.56	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
5.56	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
5.56	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
5.56	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
5.56	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
5.56	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
5.56	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.56	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
5.56	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
5.56	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
5.56	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.56	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
5.56	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
5.56	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
5.56	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
5.41	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
5.41	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
5.26	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
5.26	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
5.26	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
5.26	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
5.26	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
5.26	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
5.26	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
5.26	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
5.26	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
5.26	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
5.26	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
5.26	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
5.26	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
5.26	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.26	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.26	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
5.26	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
5.26	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
5.26	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
5.26	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
5.26	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
5.26	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
5.26	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
5.26	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
5.26	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
5.26	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.26	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
5.26	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
5.26	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
5.26	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
5.26	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
5.26	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
5.26	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
5.26	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
5.26	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
5.26	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.26	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
5.26	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
5.26	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
5.26	Consensus	blt_off	Orthosteric Ligand	blt1_off
5.26	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
5.26	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
5.26	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
5.26	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
5.26	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
5.26	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
5.26	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
5.26	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
5.26	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
5.26	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
5.26	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
5.26	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
5.26	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
5.26	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
5.26	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
5.26	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
5.00	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
5.00	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
5.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
5.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
5.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
5.00	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
5.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
5.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
5.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
5.00	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
5.00	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
5.00	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
5.00	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
5.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
5.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
5.00	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
5.00	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
5.00	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
5.00	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
5.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
5.00	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
5.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
5.00	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
5.00	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
5.00	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
5.00	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.00	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
5.00	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
5.00	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
5.00	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
5.00	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
5.00	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
5.00	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
5.00	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
5.00	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
5.00	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
5.00	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.00	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
5.00	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.00	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.00	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
5.00	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
4.76	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
4.76	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
4.76	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
4.76	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
4.76	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
4.76	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
4.76	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.76	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
4.76	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.76	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
4.76	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
4.76	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
4.76	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
4.76	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
4.76	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
4.76	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
4.76	Consensus	class-d_off	Orthosteric Ligand	ste2_off
4.76	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
4.76	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
4.76	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
4.76	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
4.76	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
4.76	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
4.76	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
4.76	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
4.76	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
4.55	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
4.55	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
4.55	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
4.55	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
4.55	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
4.55	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
4.55	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
4.55	Single	7QA8	Peptide	7QA8-STE2-Peptide
4.55	Single	7QA8	Peptide	7QA8-STE2-Peptide
4.55	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
4.55	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.55	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
4.55	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
4.55	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
4.55	Consensus	class-d_off	Orthosteric Ligand	ste2_off
4.55	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
4.55	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
4.55	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
4.35	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
4.35	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
4.35	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.35	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.35	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
4.35	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
4.35	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.35	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
4.35	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
4.35	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
4.35	Consensus	sst_off	Orthosteric Ligand	sst2_off
4.17	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
4.17	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
4.17	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
4.17	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
4.17	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
4.17	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
4.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
4.00	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
4.00	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
3.85	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
3.85	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
3.85	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
3.85	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
3.85	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.85	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
3.70	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
3.70	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
3.70	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
3.70	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
3.70	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
3.70	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.70	Consensus	class-d_on	Orthosteric Ligand	ste2_on
3.70	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
3.70	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
3.70	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
3.57	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
3.57	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
3.57	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
3.57	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
3.57	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
3.57	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
3.57	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
3.57	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
3.57	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
3.45	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
3.45	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
3.45	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
3.45	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
3.45	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
3.33	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
3.33	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
3.33	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
3.33	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
3.33	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
3.33	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
3.33	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
3.12	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
3.12	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
3.03	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
3.03	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
2.86	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.63	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
2.50	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:K75	R:R:R70	2.48	3	No	No	6	6	1	1
R:R:R70	W:W:?1	4.88	3	No	Yes	6	0	1	0
R:R:E153	R:R:K75	14.85	0	No	No	7	6	2	1
R:R:K75	W:W:?1	4.25	3	No	Yes	6	0	1	0
R:R:L78	W:W:?1	9.73	0	No	Yes	5	0	1	0
R:R:H79	R:R:I126	2.65	3	Yes	Yes	9	7	1	2
R:R:H79	R:R:V156	4.15	3	Yes	Yes	9	5	1	2
R:R:H79	R:R:W161	6.35	3	Yes	Yes	9	9	1	1
R:R:H79	W:W:?1	18.07	3	Yes	Yes	9	0	1	0
R:R:V82	W:W:?1	5.98	0	No	Yes	5	0	1	0
R:R:S122	R:R:W161	7.41	0	No	Yes	7	9	2	1
R:R:I126	R:R:V160	4.61	0	Yes	No	7	7	2	2
R:R:V156	R:R:Y157	7.57	3	Yes	No	5	7	2	1
R:R:Y157	W:W:?1	9.42	0	No	Yes	7	0	1	0
R:R:V160	R:R:W161	8.58	0	No	Yes	7	9	2	1
R:R:W161	W:W:?1	9.15	3	Yes	Yes	9	0	1	0
R:R:L165	W:W:?1	4.17	0	No	Yes	3	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
87.50	Single	8U4O	Cholesterol	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
75.00	Single	8U4P	Cholesterol	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
62.50	Single	8U4N	Cholesterol	8U4N-CXCR4-Cholesterol-Gi1/&β;1/&γ;2
50.00	Single	8U4R	Cholesterol	8U4R-CXCR4-REGN7663-Fab-Cholesterol
40.00	Single	6KQI	ORG27569	6KQI-CB₁-PubMed 104895-ORG27569
40.00	Consensus	cb1_off_allo	Other Ligand	6KQI-CB₁-PubMed 104895-ORG27569
27.27	Single	8T3O	2Y5	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.27	Consensus	ffa4_on_allo	Other Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.75	Consensus	adgrf1_on_allo	Other Ligand	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2 8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
14.29	Single	5NDZ	AZ3451; Na	5NDZ-PAR2-AZ3451; Na
13.33	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
13.33	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/&β;1/&γ;2
11.11	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2
10.53	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/&β;1/&γ;2
6.67	Single	7FEE	ZCZ011	7FEE-CB₁-PubMed 104895-ZCZ011
5.88	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/&β;1/&γ;2
5.88	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.56	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2

PDB Summary
PDB	8U4Q
Class	A
SubFamily	Protein
Type	Chemokine
SubType	CXCR4
Species	Homo sapiens
Ligand	REGN7663-Fab
Other Ligand(s)	Cholesterol
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3.36
Date	2024-03-13
D.O.I.	10.1101/2024.02.09.579708

Net Summary
I_min	1.71
Number of Linked Nodes	1260
Number of Links	1691
Number of Hubs	316
Number of Links mediated by Hubs	1145
Number of Communities	26
Number of Nodes involved in Communities	487
Number of Links involved in Communities	762

Path Summary
Number Of Nodes in MetaPath	118
Number Of Links MetaPath	117
Number of Shortest Paths	24576005
Length Of Smallest Path	3
Average Path Length	75.2244
Length of Longest Path	92
Minimum Path Strength	1.24
Average Path Strength	7.75348
Maximum Path Strength	16.875
Minimum Path Correlation	0.7
Average Path Correlation	1
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.73973
Average % Of Corr. Nodes	58.1675
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	67.9915
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	CLR
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	CLR
Name	Cholesterol
Synonyms	Cholest-5-en-3beta-ol Cholesterin (3β,14β,17α)-cholest-5-en-3-ol Cholesterol
Identifier	(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Formula	C27 H46 O
Molecular Weight	386.654
SMILES	CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
PubChem	5997
Formal Charge	0
Total Atoms	74
Total Chiral Atoms	8
Total Bonds	77
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P61073
Sequence	>8U4Q_Chain_R M K E P C F R E E N A N F N K I F L P T I Y S I I F L T G I V G N G L V I L V M G Y Q K K L R S M T D K Y R L H L S V A D L L F V I T L P F W A V D A V A N W Y F G N F L C K A V H V I Y T V S L Y S S V L I L A F I S L D R Y L A I V H A T N S Q R P R K L L A E K V V Y V G V W I P A L L L T I P D F I F A N V S E A D D R Y I C D R F Y P N D L W V V V F Q F Q H I M V G L I L P G I V I L S C Y C I I I S K L S H S K G H Q K R K A L K T T V I L I L A F F A C W L P Y Y I G I S I D S F I L L E I I K Q G C E F E N T V H K W I S I T E A L A F F H C C L N P I L Y A F L G A K F K T S A Q H A L T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8U4Q_Chain_A S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K C T I V K Q M T G I V E T H F T F K D L H F K M F D V T A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E D E E M N R M H A S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8U4Q_Chain_B Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8U4Q_Chain_G A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	3ODU	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	2.5	2010-10-27	10.1126/science.1194396
	3OE0	A	Protein	Chemokine	CXCR4	Homo sapiens	-	CVX15	-	2.9	2010-10-27	10.1126/science.1194396
	3OE6	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.2	2010-10-27	10.1126/science.1194396
	3OE8	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
	3OE9	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
	4RWS	A	Protein	Chemokine	CXCR4	Homo sapiens	vMIP-II	-	-	3.1	2015-02-11	10.1126/science.1261064
	8U4N	A	Protein	Chemokine	CXCR4	Homo sapiens	-	Cholesterol	Gi1/&β;1/&γ;2	2.72	2024-03-13	10.1101/2024.02.09.579708
	8U4O	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	Cholesterol	Gi1/&β;1/&γ;2	3.29	2024-03-13	10.1101/2024.02.09.579708
	8U4P	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	Cholesterol	Gi1/&β;1/&γ;2	3.15	2024-03-13	10.1101/2024.02.09.579708
	8U4Q	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	Cholesterol	Gi1/&β;1/&γ;2	3.36	2024-03-13	10.1101/2024.02.09.579708
	8U4R	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	Cholesterol	-	3.1	2024-03-13	10.1101/2024.02.09.579708
	3ODU (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	2.5	2010-10-27	10.1126/science.1194396
	3OE8 (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
	3OE9 (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396

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Download 8U4Q.zip

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