psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:E14	A:A:K10	12.15	No	No	0	3	3
2	A:A:K17	A:A:V13	6.07	No	No	0	4	3
3	A:A:V13	B:B:N88	7.39	No	Yes	0	3	7
4	A:A:E14	A:A:K17	6.75	No	No	0	3	4
5	A:A:S16	B:B:N88	8.94	No	Yes	0	7	7
6	A:A:S16	B:B:K89	3.06	No	Yes	0	7	9
7	A:A:I19	B:B:K89	7.27	No	Yes	0	9	9
8	A:A:D20	A:A:R24	10.72	No	No	0	6	3
9	A:A:D20	B:B:K89	8.3	No	Yes	0	6	9
10	A:A:R21	A:A:R24	7.46	No	No	0	4	3
11	A:A:E25	A:A:N22	7.89	No	No	0	4	4
12	A:A:L23	B:B:K78	5.64	No	No	0	6	8
13	A:A:L23	B:B:I80	4.28	No	Yes	0	6	8
14	A:A:L23	B:B:A92	3.15	No	No	0	6	6
15	A:A:D26	B:B:K78	8.3	No	No	0	5	8
16	A:A:E28	R:R:K149	5.4	No	No	0	4	6
17	A:A:R32	R:R:Q145	4.67	No	No	0	4	5
18	A:A:R32	R:R:R146	14.93	No	No	0	4	5
19	A:A:E33	A:A:H195	13.54	No	No	0	6	4
20	A:A:E33	A:A:K197	4.05	No	No	0	6	6
21	A:A:L36	A:A:V34	2.98	No	Yes	9	7	5
22	A:A:L194	A:A:V34	4.47	Yes	Yes	9	4	5
23	A:A:F196	A:A:V34	9.18	Yes	Yes	9	7	5
24	A:A:T219	A:A:V34	6.35	No	Yes	0	7	5
25	A:A:V339	A:A:V34	8.02	No	Yes	9	8	5
26	A:A:F199	A:A:K35	9.93	Yes	No	0	5	9
27	A:A:K35	A:A:V218	3.04	No	No	0	9	9
28	A:A:F196	A:A:L36	6.09	Yes	No	9	7	7
29	A:A:L36	A:A:M198	4.24	No	Yes	0	7	7
30	A:A:L37	A:A:L39	5.54	Yes	No	0	9	9
31	A:A:L37	A:A:V201	2.98	Yes	No	0	9	9
32	A:A:F215	A:A:L37	14.61	Yes	Yes	0	9	9
33	A:A:L37	A:A:V218	2.98	Yes	No	0	9	9
34	A:A:I49	A:A:L38	4.28	No	No	17	7	8
35	A:A:L38	A:A:M198	12.72	No	Yes	0	8	7
36	A:A:I222	A:A:L38	5.71	Yes	No	17	7	8
37	A:A:A41	A:A:S246	3.42	No	No	0	7	9
38	A:A:A41	A:A:L249	3.15	No	No	0	7	9
39	A:A:E43	A:A:G45	4.91	Yes	No	0	9	9
40	A:A:C47	A:A:E43	4.56	No	Yes	0	9	9
41	A:A:C224	A:A:E43	4.56	No	Yes	0	7	9
42	A:A:K46	A:A:S44	6.12	No	No	18	9	9
43	A:A:S44	A:A:T202	3.2	No	Yes	18	9	9
44	A:A:K46	A:A:T202	4.5	No	Yes	18	9	9
45	A:A:C47	A:A:T48	5.07	No	No	0	9	9
46	A:A:C47	A:A:N269	6.3	No	No	0	9	9
47	A:A:I222	A:A:I49	4.42	Yes	No	17	7	7
48	A:A:C224	A:A:I49	3.27	No	No	0	7	7
49	A:A:N331	A:A:Q52	5.28	No	No	0	8	9
50	A:A:F189	A:A:M53	6.22	Yes	No	0	9	8
51	A:A:T182	B:B:N119	4.39	No	No	0	7	9
52	A:A:G183	B:B:N119	5.09	No	No	0	9	9
53	A:A:F199	A:A:I184	5.02	Yes	No	1	5	9
54	A:A:I184	A:A:V201	3.07	No	No	0	9	9
55	A:A:I184	B:B:W99	7.05	No	Yes	1	9	9
56	A:A:E186	A:A:F199	5.83	No	Yes	1	9	5
57	A:A:E186	B:B:W99	6.54	No	Yes	1	9	9
58	A:A:H188	A:A:H195	5.97	No	No	0	3	4
59	A:A:H188	A:A:K197	10.48	No	No	0	3	6
60	A:A:F189	A:A:F196	16.08	Yes	Yes	0	9	7
61	A:A:F189	A:A:M198	7.46	Yes	Yes	0	9	7
62	A:A:F189	A:A:V332	3.93	Yes	No	0	9	7
63	A:A:H195	A:A:T190	9.58	No	No	0	4	3
64	A:A:F191	A:A:K192	13.65	Yes	No	9	5	4
65	A:A:F191	A:A:V332	10.49	Yes	No	0	5	7
66	A:A:F191	A:A:Q333	7.03	Yes	Yes	9	5	5
67	A:A:F191	A:A:F336	8.57	Yes	Yes	9	5	8
68	A:A:K192	A:A:Q333	5.42	No	Yes	9	4	5
69	A:A:F336	A:A:K192	7.44	Yes	No	9	8	4
70	A:A:F196	A:A:L194	7.31	Yes	Yes	9	7	4
71	A:A:F336	A:A:L194	6.09	Yes	Yes	9	8	4
72	A:A:L194	R:R:T142	5.9	Yes	No	0	4	5
73	A:A:F196	A:A:F336	3.22	Yes	Yes	9	7	8
74	A:A:F196	A:A:V339	3.93	Yes	No	9	7	8
75	A:A:F199	A:A:F215	5.36	Yes	Yes	1	5	9
76	A:A:F199	B:B:W99	14.03	Yes	Yes	1	5	9
77	A:A:D200	A:A:T202	13.01	No	Yes	0	9	9
78	A:A:V201	A:A:W211	7.36	No	Yes	0	9	9
79	A:A:Q204	A:A:S206	4.33	Yes	Yes	1	9	8
80	A:A:Q204	A:A:W211	9.86	Yes	Yes	1	9	9
81	A:A:Q204	B:B:L117	3.99	Yes	Yes	1	9	9
82	A:A:Q204	B:B:Y145	7.89	Yes	Yes	1	9	8
83	A:A:S206	A:A:W211	3.71	Yes	Yes	1	8	9
84	A:A:S206	B:B:Y145	7.63	Yes	Yes	1	8	8
85	A:A:S206	B:B:D186	5.89	Yes	Yes	1	8	9
86	A:A:E207	A:A:K209	6.75	No	No	0	9	8
87	A:A:R208	A:A:W211	4	Yes	Yes	1	9	9
88	A:A:I212	A:A:R208	6.26	Yes	Yes	1	8	9
89	A:A:L249	A:A:R208	3.64	No	Yes	0	9	9
90	A:A:I253	A:A:R208	3.76	No	Yes	0	8	9
91	A:A:K209	A:A:K210	4.31	No	Yes	1	8	9
92	A:A:K209	B:B:D228	4.15	No	Yes	1	8	9
93	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
94	A:A:K210	B:B:M188	11.52	Yes	No	1	9	8
95	A:A:K210	B:B:C204	4.85	Yes	Yes	1	9	7
96	A:A:K210	B:B:D228	8.3	Yes	Yes	1	9	9
97	A:A:K210	B:B:N230	5.6	Yes	No	1	9	9
98	A:A:K210	B:B:D246	5.53	Yes	Yes	1	9	9
99	A:A:I212	A:A:W211	3.52	Yes	Yes	1	8	9
100	A:A:F215	A:A:W211	4.01	Yes	Yes	1	9	9
101	A:A:W211	B:B:L117	3.42	Yes	Yes	1	9	9
102	A:A:W211	B:B:Y145	5.79	Yes	Yes	1	9	8
103	A:A:I212	A:A:N256	4.25	Yes	No	1	8	8
104	A:A:F259	A:A:I212	5.02	Yes	Yes	1	9	8
105	A:A:C214	A:A:H213	2.95	Yes	Yes	1	7	8
106	A:A:H213	A:A:W258	12.7	Yes	Yes	1	8	5
107	A:A:H213	B:B:Y59	8.71	Yes	Yes	1	8	8
108	A:A:H213	B:B:W332	7.41	Yes	Yes	1	8	9
109	A:A:C214	B:B:Y59	5.38	Yes	Yes	1	7	8
110	A:A:C214	B:B:Q75	3.05	Yes	No	1	7	9
111	A:A:C214	B:B:L117	3.17	Yes	Yes	1	7	9
112	A:A:F215	B:B:W99	9.02	Yes	Yes	1	9	9
113	A:A:E216	A:A:W258	9.81	No	Yes	0	7	5
114	A:A:E216	B:B:K57	6.75	No	No	0	7	9
115	A:A:A220	A:A:I265	3.25	No	Yes	0	8	8
116	A:A:F259	A:A:I221	8.79	Yes	No	1	9	8
117	A:A:I221	A:A:T262	3.04	No	No	1	8	7
118	A:A:I221	A:A:I264	2.94	No	No	0	8	6
119	A:A:I222	A:A:I265	4.42	Yes	Yes	0	7	8
120	A:A:I222	A:A:V335	3.07	Yes	No	0	7	8
121	A:A:F223	A:A:L249	7.31	No	No	0	9	9
122	A:A:F223	A:A:F250	13.93	No	Yes	0	9	9
123	A:A:F223	A:A:I253	6.28	No	No	0	9	8
124	A:A:C224	A:A:N269	6.3	No	No	0	7	9
125	A:A:M243	A:A:V225	3.04	Yes	Yes	3	8	7
126	A:A:S246	A:A:V225	4.85	No	Yes	3	9	7
127	A:A:L268	A:A:V225	2.98	Yes	Yes	0	8	7
128	A:A:F307	A:A:V225	11.8	Yes	Yes	3	8	7
129	A:A:A226	A:A:D229	6.18	No	No	0	8	8
130	A:A:A226	A:A:K270	4.82	No	Yes	0	8	9
131	A:A:L227	A:A:L268	11.07	No	Yes	0	7	8
132	A:A:F274	A:A:L227	7.31	Yes	No	0	9	7
133	A:A:I303	A:A:L227	4.28	No	No	0	7	7
134	A:A:K270	A:A:S228	6.12	Yes	No	3	9	9
135	A:A:L273	A:A:S228	9.01	Yes	No	3	6	9
136	A:A:K277	A:A:S228	3.06	No	No	3	9	9
137	A:A:D229	A:A:R242	10.72	No	No	0	8	9
138	A:A:D231	A:A:Y230	9.2	Yes	Yes	3	9	8
139	A:A:F274	A:A:Y230	5.16	Yes	Yes	3	9	8
140	A:A:K277	A:A:Y230	7.17	No	Yes	3	9	8
141	A:A:I278	A:A:Y230	7.25	No	Yes	3	6	8
142	A:A:L283	A:A:Y230	5.86	Yes	Yes	3	7	8
143	A:A:D231	A:A:L232	4.07	Yes	No	0	9	8
144	A:A:D231	A:A:K277	12.44	Yes	No	3	9	9
145	A:A:D231	A:A:S281	2.94	Yes	No	0	9	7
146	A:A:D231	A:A:I285	4.2	Yes	No	0	9	3
147	A:A:L232	A:A:R242	9.72	No	No	0	8	9
148	A:A:E236	A:A:L234	3.98	No	No	0	9	8
149	A:A:L234	A:A:M240	4.24	No	Yes	0	8	6
150	A:A:D237	A:A:M240	4.16	No	Yes	0	8	6
151	A:A:M243	A:A:N241	4.21	Yes	No	3	8	9
152	A:A:H244	A:A:N241	16.58	Yes	No	3	4	9
153	A:A:C286	A:A:N241	6.3	Yes	No	3	6	9
154	A:A:C286	A:A:M243	3.24	Yes	Yes	3	6	8
155	A:A:F307	A:A:M243	3.73	Yes	Yes	3	8	8
156	A:A:H244	A:A:M247	3.94	Yes	No	0	4	6
157	A:A:C286	A:A:H244	8.85	Yes	Yes	3	6	4
158	A:A:F307	A:A:S246	3.96	Yes	No	3	8	9
159	A:A:M247	A:A:Y287	8.38	No	Yes	0	6	7
160	A:A:F307	A:A:M247	8.71	Yes	No	0	8	6
161	A:A:F250	A:A:I264	3.77	Yes	No	0	9	6
162	A:A:F250	A:A:F307	10.72	Yes	Yes	0	9	8
163	A:A:F250	A:A:L310	4.87	Yes	No	0	9	4
164	A:A:F250	A:A:I319	5.02	Yes	No	0	9	5
165	A:A:D251	A:A:N255	8.08	No	No	13	5	8
166	A:A:D251	A:A:L310	13.57	No	No	0	5	4
167	A:A:D251	A:A:K312	4.15	No	No	13	5	5
168	A:A:C254	A:A:N255	4.72	No	No	13	5	8
169	A:A:C254	A:A:N311	4.72	No	Yes	13	5	8
170	A:A:C254	A:A:K317	6.47	No	Yes	13	5	7
171	A:A:K312	A:A:N255	11.19	No	No	13	5	8
172	A:A:N256	A:A:W258	10.17	No	Yes	1	8	5
173	A:A:F259	A:A:N256	4.83	Yes	No	1	9	8
174	A:A:K257	A:A:W258	15.08	No	Yes	0	4	5
175	A:A:W258	B:B:R314	5	Yes	No	1	5	8
176	A:A:W258	B:B:W332	3.75	Yes	Yes	1	5	9
177	A:A:F259	A:A:T262	5.19	Yes	No	1	9	7
178	A:A:D261	A:A:T260	4.34	No	No	0	4	3
179	A:A:R313	A:A:T260	11.64	No	No	0	4	3
180	A:A:S263	A:A:Y320	5.09	No	Yes	14	7	7
181	A:A:S263	A:A:V342	3.23	No	No	14	7	7
182	A:A:I264	A:A:K317	5.82	No	Yes	0	6	7
183	A:A:F267	A:A:I265	3.77	Yes	Yes	0	9	8
184	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
185	A:A:F307	A:A:L266	3.65	Yes	No	0	8	9
186	A:A:L266	A:A:T321	10.32	No	Yes	0	9	5
187	A:A:F267	A:A:H322	5.66	Yes	Yes	19	9	9
188	A:A:F267	A:A:T324	6.49	Yes	No	0	9	9
189	A:A:F267	A:A:F334	3.22	Yes	No	19	9	3
190	A:A:F267	A:A:V335	3.93	Yes	No	0	9	8
191	A:A:L268	A:A:T321	2.95	Yes	Yes	0	8	5
192	A:A:F323	A:A:L268	7.31	No	Yes	0	4	8
193	A:A:N269	A:A:T324	7.31	No	No	0	9	9
194	A:A:K270	A:A:L273	4.23	Yes	Yes	3	9	6
195	A:A:K271	A:A:Y296	7.17	No	Yes	0	5	4
196	A:A:F274	A:A:I278	5.02	Yes	No	3	9	6
197	A:A:F274	A:A:Y296	4.13	Yes	Yes	0	9	4
198	A:A:E275	A:A:K279	5.4	No	No	0	5	2
199	A:A:E275	A:A:Y296	13.47	No	Yes	0	5	4
200	A:A:K279	A:A:K280	4.31	No	No	0	2	1
201	A:A:P282	A:A:S281	3.56	No	No	0	5	7
202	A:A:P282	A:A:T284	5.25	No	No	0	5	4
203	A:A:L283	A:A:Y287	7.03	Yes	Yes	3	7	7
204	A:A:L283	A:A:Y290	9.38	Yes	Yes	3	7	7
205	A:A:I303	A:A:L283	4.28	No	Yes	3	7	7
206	A:A:C286	A:A:Y287	14.79	Yes	Yes	3	6	7
207	A:A:E289	A:A:Y287	5.61	No	Yes	3	6	7
208	A:A:Y287	A:A:Y302	13.9	Yes	Yes	3	7	6
209	A:A:I303	A:A:Y287	7.25	No	Yes	3	7	7
210	A:A:Q306	A:A:Y287	11.27	No	Yes	3	5	7
211	A:A:E289	A:A:P288	6.29	No	No	0	6	5
212	A:A:E289	A:A:Y302	7.86	No	Yes	3	6	6
213	A:A:G292	A:A:Y290	7.24	No	Yes	3	7	7
214	A:A:E298	A:A:Y290	5.61	No	Yes	3	4	7
215	A:A:A299	A:A:Y290	4	No	Yes	0	7	7
216	A:A:Y290	A:A:Y302	18.86	Yes	Yes	3	7	6
217	A:A:E298	A:A:G292	4.91	No	No	3	4	7
218	A:A:S293	A:A:T295	4.8	No	No	0	3	5
219	A:A:E298	A:A:S293	7.19	No	No	0	4	3
220	A:A:E297	A:A:Y296	4.49	No	Yes	0	4	4
221	A:A:A300	A:A:Y296	5.34	No	Yes	0	5	4
222	A:A:F323	A:A:Y296	4.13	No	Yes	0	4	4
223	A:A:Q306	A:A:Y302	18.04	No	Yes	3	5	6
224	A:A:E308	A:A:Q304	10.19	No	No	20	3	5
225	A:A:Q304	A:A:T321	17.01	No	Yes	20	5	5
226	A:A:F323	A:A:Q304	4.68	No	No	0	4	5
227	A:A:E308	A:A:T321	7.06	No	Yes	20	3	5
228	A:A:K314	A:A:N311	5.6	No	Yes	0	3	8
229	A:A:K317	A:A:N311	6.99	Yes	Yes	13	7	8
230	A:A:I319	A:A:N311	5.66	No	Yes	0	5	8
231	A:A:R313	A:A:T316	3.88	No	No	0	4	3
232	A:A:K317	A:A:R313	3.71	Yes	No	0	7	4
233	A:A:D315	R:R:H232	5.04	No	No	0	3	4
234	A:A:E318	A:A:Y320	17.96	No	Yes	14	4	7
235	A:A:E318	A:A:K345	8.1	No	Yes	14	4	5
236	A:A:A338	A:A:Y320	8.01	No	Yes	0	6	7
237	A:A:D341	A:A:Y320	9.2	No	Yes	14	8	7
238	A:A:V342	A:A:Y320	5.05	No	Yes	14	7	7
239	A:A:K345	A:A:Y320	3.58	Yes	Yes	14	5	7
240	A:A:H322	A:A:K330	5.24	Yes	No	0	9	4
241	A:A:H322	A:A:N331	7.65	Yes	No	0	9	8
242	A:A:F334	A:A:H322	22.63	No	Yes	19	3	9
243	A:A:N331	A:A:T324	5.85	No	No	0	8	9
244	A:A:C325	A:A:K330	6.47	No	No	0	7	4
245	A:A:T327	A:A:T329	3.14	No	No	0	8	9
246	A:A:F336	A:A:Q333	4.68	Yes	Yes	9	8	5
247	A:A:D337	A:A:Q333	9.14	No	Yes	9	4	5
248	A:A:D337	A:A:F336	3.58	No	Yes	9	4	8
249	A:A:F336	A:A:T340	7.78	Yes	No	0	8	6
250	A:A:I343	A:A:V339	3.07	Yes	No	0	7	8
251	A:A:D341	A:A:K345	5.53	No	Yes	14	8	5
252	A:A:D341	R:R:K234	6.91	No	No	0	8	7
253	A:A:N346	A:A:V342	4.43	No	No	0	4	7
254	A:A:I343	A:A:N347	4.25	Yes	No	0	7	8
255	A:A:I343	R:R:T142	3.04	Yes	No	0	7	5
256	A:A:K345	R:R:Q233	4.07	Yes	No	0	5	5
257	A:A:N347	R:R:A137	4.69	No	No	0	8	8
258	A:A:L348	A:A:L353	4.15	No	No	0	9	7
259	A:A:L348	R:R:I138	5.71	No	No	0	9	8
260	A:A:L348	R:R:A237	4.73	No	No	0	9	7
261	A:A:F354	A:A:K349	4.96	Yes	No	0	5	5
262	A:A:D350	R:R:K308	5.53	No	No	0	4	6
263	A:A:C351	R:R:R134	4.18	No	Yes	0	4	9
264	A:A:L353	R:R:R134	9.72	No	Yes	0	7	9
265	A:A:L353	R:R:T241	5.9	No	Yes	0	7	7
266	A:A:F354	R:R:Q233	16.4	Yes	No	0	5	5
267	A:A:F354	R:R:K236	8.69	Yes	No	0	5	8
268	B:B:L7	G:G:A12	4.73	No	No	0	8	5
269	B:B:L7	G:G:V16	2.98	No	Yes	0	8	7
270	B:B:E12	B:B:R8	24.42	No	No	0	4	3
271	B:B:E10	G:G:V16	7.13	No	Yes	0	8	7
272	B:B:L14	G:G:L19	5.54	No	No	0	8	9
273	B:B:L14	G:G:K20	5.64	No	No	0	8	6
274	B:B:N16	B:B:R19	9.64	No	No	0	1	4
275	B:B:Q17	G:G:A23	3.03	No	No	0	4	8
276	B:B:I18	B:B:R22	3.76	No	No	0	7	6
277	B:B:I18	G:G:A23	3.25	No	No	0	7	8
278	B:B:I18	G:G:R27	5.01	No	Yes	0	7	8
279	B:B:A21	G:G:R27	5.53	No	Yes	0	4	8
280	B:B:D258	B:B:R22	14.29	No	No	0	7	6
281	B:B:Q259	B:B:R22	9.35	No	No	0	6	6
282	B:B:A26	B:B:K23	3.21	No	No	0	3	2
283	B:B:A26	B:B:Q259	3.03	No	No	0	3	6
284	B:B:D27	G:G:S31	4.42	No	No	0	8	9
285	B:B:Q32	B:B:T29	11.34	No	No	0	1	3
286	B:B:L261	B:B:L30	5.54	No	No	0	5	5
287	B:B:L30	B:B:M262	7.07	No	Yes	0	5	4
288	B:B:L30	G:G:A34	4.73	No	No	0	5	6
289	B:B:I33	G:G:A34	3.25	No	No	0	3	6
290	B:B:I37	B:B:T34	3.04	Yes	No	8	2	5
291	B:B:K301	B:B:T34	4.5	Yes	No	8	5	5
292	B:B:T34	G:G:M38	3.01	No	No	8	5	4
293	B:B:I37	B:B:R283	5.01	Yes	Yes	8	2	9
294	B:B:I37	B:B:L300	4.28	Yes	No	8	2	6
295	B:B:I37	B:B:K301	4.36	Yes	Yes	8	2	5
296	B:B:I37	G:G:M38	4.37	Yes	No	8	2	4
297	B:B:I37	G:G:E42	4.1	Yes	No	8	2	1
298	B:B:K301	B:B:P39	11.71	Yes	No	0	5	1
299	B:B:I43	B:B:V40	3.07	No	Yes	0	3	3
300	B:B:R283	B:B:V40	9.15	Yes	Yes	8	9	3
301	B:B:D298	B:B:V40	7.3	No	Yes	8	9	3
302	B:B:V40	G:G:L51	2.98	Yes	Yes	8	3	6
303	B:B:Q44	B:B:R42	4.67	No	No	0	4	2
304	B:B:G306	B:B:R42	3	No	No	0	4	2
305	B:B:I43	B:B:L284	5.71	No	Yes	0	3	5
306	B:B:A305	B:B:I43	3.25	No	No	0	4	3
307	B:B:L308	B:B:M45	5.65	Yes	No	0	7	4
308	B:B:M45	G:G:L50	7.07	No	No	0	4	9
309	B:B:R46	B:B:R48	6.4	No	Yes	0	5	7
310	B:B:K337	B:B:T47	9.01	Yes	No	7	6	3
311	B:B:T47	B:B:W339	3.64	No	Yes	7	3	9
312	B:B:N340	B:B:R48	4.82	No	Yes	4	9	7
313	B:B:R48	G:G:N59	3.62	Yes	Yes	4	7	9
314	B:B:R48	G:G:F61	3.21	Yes	Yes	4	7	8
315	B:B:R49	B:B:T87	5.17	No	No	0	7	5
316	B:B:I338	B:B:R49	5.01	Yes	No	4	5	7
317	B:B:R49	G:G:F61	6.41	No	Yes	4	7	8
318	B:B:R52	B:B:T50	11.64	No	No	7	7	3
319	B:B:K337	B:B:T50	7.51	Yes	No	7	6	3
320	B:B:T50	R:R:K67	3	No	No	7	3	6
321	B:B:L51	B:B:L70	4.15	Yes	Yes	4	9	5
322	B:B:L51	B:B:W82	14.81	Yes	Yes	4	9	9
323	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
324	B:B:L336	B:B:L51	8.3	No	Yes	4	7	9
325	B:B:F335	B:B:R52	6.41	Yes	No	7	4	7
326	B:B:R52	R:R:K67	4.95	No	No	7	7	6
327	B:B:H54	B:B:I58	9.28	Yes	No	4	9	9
328	B:B:H54	B:B:S72	9.76	Yes	No	4	9	9
329	B:B:H54	B:B:S74	12.55	Yes	No	4	9	9
330	B:B:D76	B:B:H54	5.04	Yes	Yes	4	9	9
331	B:B:H54	B:B:I80	13.26	Yes	Yes	4	9	8
332	B:B:H54	B:B:W82	3.17	Yes	Yes	4	9	9
333	B:B:A56	B:B:D76	3.09	No	Yes	0	7	9
334	B:B:K57	B:B:Y59	7.17	No	Yes	1	9	8
335	B:B:K57	B:B:W332	24.37	No	Yes	1	9	9
336	B:B:I58	B:B:S74	3.1	No	No	4	9	9
337	B:B:Q75	B:B:Y59	16.91	No	Yes	1	9	8
338	B:B:W332	B:B:Y59	6.75	Yes	Yes	1	9	8
339	B:B:M61	B:B:W63	4.65	No	Yes	0	6	7
340	B:B:C317	B:B:M61	4.86	No	No	0	7	6
341	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
342	B:B:H62	B:B:R150	19.18	No	No	0	6	6
343	B:B:L70	B:B:W63	7.97	Yes	Yes	4	5	7
344	B:B:S84	B:B:W63	6.18	Yes	Yes	4	5	7
345	B:B:T321	B:B:W63	12.13	No	Yes	4	7	7
346	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
347	B:B:I338	B:B:W63	4.7	Yes	Yes	4	5	7
348	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
349	B:B:D322	B:B:T65	4.34	No	No	0	1	1
350	B:B:D66	B:B:R68	3.57	No	No	0	8	5
351	B:B:D66	B:B:L69	5.43	No	No	0	8	5
352	B:B:S67	B:B:T321	7.99	No	No	4	5	7
353	B:B:D323	B:B:S67	10.31	No	No	4	7	5
354	B:B:D83	B:B:R68	15.48	No	No	0	8	5
355	B:B:R68	B:B:Y85	23.66	No	No	0	5	4
356	B:B:D83	B:B:L69	4.07	No	No	0	8	5
357	B:B:L70	B:B:W82	5.69	Yes	Yes	4	5	9
358	B:B:L70	B:B:S84	3	Yes	Yes	4	5	5
359	B:B:L79	B:B:V71	4.47	Yes	Yes	10	7	8
360	B:B:I81	B:B:V71	4.61	Yes	Yes	10	7	8
361	B:B:C103	B:B:V71	3.42	No	Yes	0	8	8
362	B:B:V71	B:B:Y105	3.79	Yes	Yes	10	8	6
363	B:B:V112	B:B:V71	4.81	Yes	Yes	10	8	8
364	B:B:S72	B:B:W82	7.41	No	Yes	4	9	9
365	B:B:L336	B:B:S72	6.01	No	No	4	7	9
366	B:B:A73	B:B:V100	3.39	No	No	0	9	9
367	B:B:A73	B:B:C103	3.61	No	No	0	9	8
368	B:B:D76	B:B:S74	8.83	Yes	No	4	9	9
369	B:B:Q75	B:B:W99	4.38	No	Yes	1	9	9
370	B:B:D76	B:B:K78	8.3	Yes	No	0	9	8
371	B:B:I93	B:B:L79	4.28	Yes	Yes	0	7	7
372	B:B:L79	B:B:L95	6.92	Yes	No	0	7	8
373	B:B:L79	B:B:V112	2.98	Yes	Yes	10	7	8
374	B:B:I80	B:B:W82	16.44	Yes	Yes	4	8	9
375	B:B:I80	B:B:K89	4.36	Yes	Yes	4	8	9
376	B:B:I81	B:B:V90	3.07	Yes	No	10	7	5
377	B:B:H91	B:B:I81	9.28	No	Yes	10	5	7
378	B:B:I81	B:B:I93	2.94	Yes	Yes	0	7	7
379	B:B:K89	B:B:W82	11.6	Yes	Yes	4	9	9
380	B:B:L336	B:B:W82	3.42	No	Yes	4	7	9
381	B:B:D83	B:B:T86	7.23	No	No	0	8	6
382	B:B:I338	B:B:S84	3.1	Yes	Yes	4	5	5
383	B:B:S84	G:G:F61	5.28	Yes	Yes	4	5	8
384	B:B:Y85	G:G:P60	13.91	No	No	0	4	9
385	B:B:Y85	G:G:F61	7.22	No	Yes	0	4	8
386	B:B:N88	B:B:T86	8.77	Yes	No	0	7	6
387	B:B:H91	B:B:V90	6.92	No	No	10	5	5
388	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
389	B:B:I93	B:B:Y124	7.25	Yes	Yes	0	7	6
390	B:B:I93	B:B:V133	10.75	Yes	No	0	7	4
391	B:B:C114	B:B:L95	6.35	No	No	0	8	8
392	B:B:L95	B:B:Y124	5.86	No	Yes	0	8	6
393	B:B:R134	B:B:R96	5.33	No	No	0	3	6
394	B:B:R96	B:B:V135	6.54	No	No	0	6	4
395	B:B:S97	B:B:W99	4.94	No	Yes	0	8	9
396	B:B:D118	B:B:S97	8.83	No	No	0	9	8
397	B:B:S98	B:B:W99	7.41	No	Yes	0	8	9
398	B:B:L117	B:B:W99	5.69	Yes	Yes	1	9	9
399	B:B:C114	B:B:V100	5.12	No	No	0	8	9
400	B:B:G116	B:B:M101	3.49	No	No	0	9	9
401	B:B:M101	B:B:Y145	9.58	No	Yes	0	9	8
402	B:B:C148	B:B:T102	3.38	No	No	0	6	8
403	B:B:C149	B:B:T102	3.38	Yes	No	0	8	8
404	B:B:G109	B:B:Y105	7.24	No	Yes	0	5	6
405	B:B:V112	B:B:Y105	3.79	Yes	Yes	10	8	6
406	B:B:L126	B:B:Y105	4.69	No	Yes	10	5	6
407	B:B:A106	B:B:F151	8.32	No	Yes	0	6	9
408	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
409	B:B:N110	B:B:S108	10.43	Yes	No	1	4	6
410	B:B:D154	B:B:S108	10.31	No	No	1	6	6
411	B:B:N110	B:B:Y111	5.81	Yes	Yes	1	4	4
412	B:B:K127	B:B:N110	6.99	No	Yes	0	4	4
413	B:B:D154	B:B:N110	8.08	No	Yes	1	6	4
414	B:B:I123	B:B:Y111	3.63	Yes	Yes	1	6	4
415	B:B:N125	B:B:Y111	12.79	No	Yes	0	4	4
416	B:B:S136	B:B:Y111	5.09	No	Yes	1	4	4
417	B:B:D154	B:B:Y111	9.2	No	Yes	1	6	4
418	B:B:V112	B:B:Y124	3.79	Yes	Yes	0	8	6
419	B:B:L126	B:B:V112	7.45	No	Yes	10	5	8
420	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
421	B:B:C114	B:B:G115	3.92	No	No	0	8	9
422	B:B:D118	B:B:I120	4.2	No	No	0	9	6
423	B:B:G144	B:B:N119	3.39	No	No	0	8	9
424	B:B:E138	B:B:I120	4.1	No	No	0	6	6
425	B:B:C121	B:B:L139	4.76	Yes	Yes	0	8	9
426	B:B:C121	B:B:L146	3.17	Yes	No	1	8	7
427	B:B:C121	B:B:C149	3.64	Yes	Yes	1	8	8
428	B:B:C121	B:B:T159	3.38	Yes	Yes	1	8	9
429	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
430	B:B:E138	B:B:S122	7.19	No	No	0	6	8
431	B:B:I123	B:B:S136	4.64	Yes	No	1	6	4
432	B:B:I123	B:B:L139	4.28	Yes	Yes	0	6	9
433	B:B:I123	B:B:I171	4.42	Yes	No	1	6	6
434	B:B:V135	B:B:Y124	7.57	No	Yes	0	4	6
435	B:B:N125	B:B:T128	4.39	No	No	0	4	3
436	B:B:N132	B:B:T128	5.85	No	No	0	3	3
437	B:B:E130	B:B:N132	5.26	No	No	0	3	3
438	B:B:E138	B:B:V135	4.28	No	No	0	6	4
439	B:B:G174	B:B:R137	3	No	No	0	4	5
440	B:B:L139	B:B:W169	18.22	Yes	Yes	0	9	8
441	B:B:H142	B:B:T159	6.85	Yes	Yes	1	9	9
442	B:B:H142	B:B:S161	13.95	Yes	No	1	9	9
443	B:B:D163	B:B:H142	7.56	Yes	Yes	1	9	9
444	B:B:A167	B:B:H142	2.93	No	Yes	1	4	9
445	B:B:H142	B:B:W169	6.35	Yes	Yes	1	9	8
446	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
447	B:B:D163	B:B:G144	3.35	Yes	No	0	9	8
448	B:B:S147	B:B:Y145	3.82	No	Yes	0	9	8
449	B:B:G162	B:B:Y145	8.69	No	Yes	1	9	8
450	B:B:D186	B:B:Y145	9.2	Yes	Yes	1	9	8
451	B:B:M188	B:B:Y145	8.38	No	Yes	1	8	8
452	B:B:C149	B:B:L146	3.17	Yes	No	1	8	7
453	B:B:L146	B:B:T159	5.9	No	Yes	1	7	9
454	B:B:S147	B:B:S160	4.89	No	Yes	0	9	6
455	B:B:C148	B:B:S160	3.44	No	Yes	5	6	6
456	B:B:C148	B:B:L190	3.17	No	Yes	5	6	5
457	B:B:C149	B:B:I157	3.27	Yes	Yes	1	8	7
458	B:B:C149	B:B:T159	3.38	Yes	Yes	1	8	9
459	B:B:F151	B:B:I157	7.54	Yes	Yes	1	9	7
460	B:B:F151	B:B:I171	3.77	Yes	No	1	9	6
461	B:B:L152	B:B:Q156	3.99	No	No	0	3	5
462	B:B:L152	B:B:V158	2.98	No	Yes	5	3	5
463	B:B:L152	B:B:L192	5.54	No	No	5	3	5
464	B:B:D153	B:B:Q156	9.14	No	No	0	5	5
465	B:B:D170	B:B:N155	8.08	No	No	21	9	3
466	B:B:E172	B:B:N155	6.57	No	No	21	6	3
467	B:B:L168	B:B:Q156	5.32	Yes	No	0	6	5
468	B:B:I157	B:B:W169	3.52	Yes	Yes	1	7	8
469	B:B:I157	B:B:I171	5.89	Yes	No	1	7	6
470	B:B:L190	B:B:V158	4.47	Yes	Yes	5	5	5
471	B:B:L192	B:B:V158	4.47	No	Yes	5	5	5
472	B:B:F199	B:B:V158	5.24	Yes	Yes	5	9	5
473	B:B:T159	B:B:W169	9.7	Yes	Yes	1	9	8
474	B:B:S160	B:B:V187	6.46	Yes	Yes	5	6	9
475	B:B:L190	B:B:S160	6.01	Yes	Yes	5	5	6
476	B:B:G162	B:B:S161	3.71	No	No	1	9	9
477	B:B:D163	B:B:S161	10.31	Yes	No	1	9	9
478	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
479	B:B:D163	B:B:T165	10.12	Yes	No	0	9	7
480	B:B:T165	B:B:T181	3.14	No	No	0	7	2
481	B:B:C166	B:B:V187	5.12	No	Yes	5	8	9
482	B:B:C166	B:B:F199	4.19	No	Yes	5	8	9
483	B:B:C166	B:B:S201	3.44	No	Yes	5	8	9
484	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
485	B:B:A167	B:B:Q176	6.06	No	Yes	1	4	4
486	B:B:L168	B:B:T177	4.42	Yes	No	5	6	4
487	B:B:L168	B:B:T178	4.42	Yes	No	5	6	4
488	B:B:L168	B:B:V213	2.98	Yes	No	0	6	4
489	B:B:Q176	B:B:W169	14.24	Yes	Yes	1	4	8
490	B:B:D170	B:B:E172	3.9	No	No	21	9	6
491	B:B:D170	B:B:T173	7.23	No	No	0	9	5
492	B:B:Q176	B:B:T179	8.5	Yes	No	0	4	4
493	B:B:T177	B:B:T178	3.14	No	No	5	4	4
494	B:B:F180	B:B:T178	7.78	Yes	No	5	7	4
495	B:B:F180	B:B:F199	12.86	Yes	Yes	5	7	9
496	B:B:F180	B:B:W211	15.03	Yes	Yes	5	7	8
497	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
498	B:B:H183	B:B:V187	6.92	Yes	Yes	5	9	9
499	B:B:H183	B:B:S201	6.97	Yes	Yes	5	9	9
500	B:B:A203	B:B:H183	8.78	No	Yes	5	8	9
501	B:B:D205	B:B:H183	6.3	Yes	Yes	5	9	9
502	B:B:H183	B:B:K209	15.72	Yes	Yes	5	9	6
503	B:B:H183	B:B:W211	3.17	Yes	Yes	5	9	8
504	B:B:D205	B:B:T184	5.78	Yes	No	0	9	3
505	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
506	B:B:S201	B:B:V187	3.23	Yes	Yes	5	9	9
507	B:B:A203	B:B:V187	3.39	No	Yes	5	8	9
508	B:B:C204	B:B:M188	3.24	Yes	No	1	7	8
509	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
510	B:B:F199	B:B:L190	6.09	Yes	Yes	5	9	5
511	B:B:C233	B:B:S191	3.44	No	No	0	3	8
512	B:B:F234	B:B:S191	6.61	No	No	0	5	8
513	B:B:F199	B:B:L192	3.65	Yes	No	5	9	5
514	B:B:A193	B:B:D195	3.09	No	No	0	4	5
515	B:B:A193	B:B:F234	4.16	No	No	0	4	5
516	B:B:G238	B:B:P194	4.06	No	No	0	7	4
517	B:B:D195	B:B:R197	8.34	No	No	0	5	5
518	B:B:R197	B:B:R214	21.32	No	No	0	5	9
519	B:B:L198	B:B:L210	4.15	No	Yes	0	3	5
520	B:B:D212	B:B:L198	5.43	No	No	0	9	3
521	B:B:F199	B:B:W211	12.03	Yes	Yes	5	9	8
522	B:B:L210	B:B:V200	2.98	Yes	Yes	0	5	6
523	B:B:I232	B:B:V200	7.68	Yes	Yes	6	8	6
524	B:B:F234	B:B:V200	10.49	No	Yes	0	5	6
525	B:B:F241	B:B:V200	7.87	Yes	Yes	6	6	6
526	B:B:S201	B:B:W211	7.41	Yes	Yes	5	9	8
527	B:B:G202	B:B:I229	5.29	No	No	0	6	7
528	B:B:A203	B:B:D205	3.09	No	Yes	5	8	9
529	B:B:C204	B:B:D228	12.45	Yes	Yes	1	7	9
530	B:B:D205	B:B:S207	5.89	Yes	No	0	9	5
531	B:B:S207	B:B:T223	3.2	No	No	0	5	2
532	B:B:K209	B:B:W211	8.12	Yes	Yes	5	6	8
533	B:B:C218	B:B:K209	6.47	No	Yes	5	5	6
534	B:B:K209	B:B:T221	12.01	Yes	No	0	6	7
535	B:B:L210	B:B:R219	4.86	Yes	No	0	5	5
536	B:B:L210	B:B:Q220	6.65	Yes	Yes	0	5	7
537	B:B:L210	B:B:L255	5.54	Yes	No	0	5	6
538	B:B:C218	B:B:W211	7.84	No	Yes	5	5	8
539	B:B:D212	B:B:E215	9.09	No	No	0	9	3
540	B:B:D212	B:B:R219	9.53	No	No	0	9	5
541	B:B:E215	B:B:M217	6.77	No	No	0	3	3
542	B:B:M217	B:B:R219	4.96	No	No	0	3	5
543	B:B:C218	G:G:Q18	6.1	No	No	0	5	9
544	B:B:F222	B:B:Q220	7.03	No	Yes	0	8	7
545	B:B:D258	B:B:Q220	11.75	No	Yes	0	7	7
546	B:B:Q220	G:G:I25	4.12	Yes	No	0	7	2
547	B:B:T221	G:G:E22	8.47	No	No	0	7	9
548	B:B:F222	B:B:F241	12.86	No	Yes	6	8	6
549	B:B:F222	B:B:F253	10.72	No	Yes	6	8	6
550	B:B:H225	B:B:I229	7.95	Yes	No	6	9	7
551	B:B:H225	B:B:T243	8.21	Yes	Yes	6	9	8
552	B:B:H225	B:B:S245	12.55	Yes	No	6	9	9
553	B:B:D247	B:B:H225	7.56	Yes	Yes	6	9	9
554	B:B:H225	B:B:T249	4.11	Yes	Yes	6	9	6
555	B:B:H225	B:B:R251	11.28	Yes	Yes	6	9	8
556	B:B:D247	B:B:E226	10.39	Yes	No	0	9	3
557	B:B:E226	B:B:R251	4.65	No	Yes	0	3	8
558	B:B:D246	B:B:S227	5.89	Yes	No	0	9	6
559	B:B:D247	B:B:S227	2.94	Yes	No	0	9	6
560	B:B:D228	B:B:D246	5.32	Yes	Yes	1	9	9
561	B:B:I229	B:B:T243	6.08	No	Yes	6	7	8
562	B:B:D246	B:B:N230	13.46	Yes	No	1	9	9
563	B:B:A231	B:B:V276	5.09	No	No	0	5	6
564	B:B:F241	B:B:I232	5.02	Yes	Yes	6	6	8
565	B:B:I232	B:B:T243	4.56	Yes	Yes	6	8	8
566	B:B:F235	B:B:P236	11.56	Yes	Yes	15	6	7
567	B:B:F235	B:B:N237	6.04	Yes	No	15	6	5
568	B:B:F235	B:B:F278	9.65	Yes	Yes	15	6	7
569	B:B:F235	B:B:G282	4.52	Yes	No	15	6	9
570	B:B:F235	G:G:L37	10.96	Yes	No	0	6	7
571	B:B:F235	G:G:Y40	4.13	Yes	Yes	15	6	6
572	B:B:F235	G:G:C41	4.19	Yes	No	0	6	7
573	B:B:F278	B:B:P236	4.33	Yes	Yes	15	7	7
574	B:B:G282	B:B:P236	4.06	No	Yes	15	9	7
575	B:B:P236	G:G:Y40	6.95	Yes	Yes	15	7	6
576	B:B:N237	B:B:N239	8.17	No	No	0	5	2
577	B:B:N237	G:G:Y40	10.47	No	Yes	15	5	6
578	B:B:N239	B:B:R256	14.46	No	No	0	2	9
579	B:B:F241	B:B:F253	11.79	Yes	Yes	6	6	6
580	B:B:A242	B:B:L285	3.15	No	No	0	4	6
581	B:B:F253	B:B:T243	7.78	Yes	Yes	6	6	8
582	B:B:G244	B:B:I273	5.29	No	No	0	5	6
583	B:B:D247	B:B:S245	10.31	Yes	No	6	9	9
584	B:B:D247	B:B:T249	11.56	Yes	Yes	6	9	6
585	B:B:A248	B:B:I269	3.25	No	No	0	5	4
586	B:B:T249	B:B:T263	3.14	Yes	Yes	6	6	1
587	B:B:S265	B:B:T249	4.8	No	Yes	6	2	6
588	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
589	B:B:C250	B:B:I273	6.55	No	No	0	8	6
590	B:B:E260	B:B:R251	22.1	No	Yes	6	6	8
591	B:B:R251	B:B:T263	12.94	Yes	Yes	6	8	1
592	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
593	B:B:E260	B:B:F253	5.83	No	Yes	6	6	6
594	B:B:A257	B:B:D254	4.63	No	No	0	7	9
595	B:B:D254	G:G:A33	6.18	No	No	0	9	7
596	B:B:R256	G:G:I28	7.52	No	No	0	9	4
597	B:B:R256	G:G:D36	7.15	No	No	0	9	5
598	B:B:D258	G:G:R27	16.68	No	Yes	0	7	8
599	B:B:Q259	G:G:V30	4.3	No	No	0	6	8
600	B:B:E260	B:B:T263	5.64	No	Yes	6	6	1
601	B:B:M262	B:B:Y264	10.78	Yes	Yes	0	4	5
602	B:B:A302	B:B:M262	3.22	No	Yes	0	2	4
603	B:B:S265	B:B:T263	3.2	No	Yes	6	2	1
604	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
605	B:B:W297	B:B:Y264	6.75	Yes	Yes	0	8	5
606	B:B:H266	B:B:N268	3.83	No	No	0	4	4
607	B:B:H266	B:B:R304	3.39	No	No	0	4	5
608	B:B:I269	B:B:Y289	6.04	No	Yes	0	4	7
609	B:B:C271	B:B:D290	6.22	No	No	0	5	6
610	B:B:C271	B:B:D291	4.67	No	No	0	5	8
611	B:B:D290	B:B:G272	3.35	No	No	0	6	4
612	B:B:I273	B:B:Y289	12.09	No	Yes	0	6	7
613	B:B:S275	B:B:T274	4.8	No	No	0	8	8
614	B:B:L318	B:B:S275	6.01	Yes	No	0	6	8
615	B:B:S277	B:B:V320	4.85	No	No	0	5	7
616	B:B:F278	B:B:G282	4.52	Yes	No	15	7	9
617	B:B:F278	B:B:L285	10.96	Yes	No	0	7	6
618	B:B:L284	B:B:S279	6.01	Yes	No	0	5	9
619	B:B:S279	G:G:D48	7.36	No	Yes	0	9	9
620	B:B:S279	G:G:L50	3	No	No	0	9	9
621	B:B:G324	B:B:K280	3.49	No	No	0	9	1
622	B:B:K280	G:G:D48	4.15	No	Yes	0	1	9
623	B:B:S281	G:G:D48	10.31	No	Yes	8	9	9
624	B:B:S281	G:G:L51	3	No	Yes	8	9	6
625	B:B:D298	B:B:R283	14.29	No	Yes	8	9	9
626	B:B:L300	B:B:R283	12.15	No	Yes	8	6	9
627	B:B:R283	G:G:L51	7.29	Yes	Yes	8	9	6
628	B:B:L284	B:B:V296	5.96	Yes	Yes	0	5	5
629	B:B:L284	G:G:L51	4.15	Yes	Yes	0	5	6
630	B:B:L286	B:B:V296	4.47	No	Yes	0	7	5
631	B:B:L286	B:B:L318	4.15	No	Yes	7	7	6
632	B:B:L286	B:B:V327	2.98	No	Yes	7	7	6
633	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
634	B:B:G288	B:B:V315	3.68	No	No	0	7	7
635	B:B:D291	B:B:Y289	8.05	No	Yes	0	8	7
636	B:B:N295	B:B:Y289	8.14	Yes	Yes	16	6	7
637	B:B:W297	B:B:Y289	7.72	Yes	Yes	16	8	7
638	B:B:D290	B:B:R314	23.82	No	No	0	6	8
639	B:B:D291	B:B:N293	5.39	No	No	0	8	5
640	B:B:A309	B:B:N293	6.25	No	No	0	3	5
641	B:B:C294	B:B:L308	9.52	No	Yes	0	5	7
642	B:B:C294	B:B:L318	3.17	No	Yes	0	5	6
643	B:B:N295	B:B:W297	4.52	Yes	Yes	16	6	8
644	B:B:N295	B:B:R304	8.44	Yes	No	16	6	5
645	B:B:N295	B:B:V307	5.91	Yes	No	0	6	3
646	B:B:G306	B:B:V296	3.68	No	Yes	0	4	5
647	B:B:L308	B:B:V296	4.47	Yes	Yes	0	7	5
648	B:B:R304	B:B:W297	11	No	Yes	16	5	8
649	B:B:D298	B:B:K301	8.3	No	Yes	8	9	5
650	B:B:L300	G:G:C41	7.94	No	No	0	6	7
651	B:B:L308	B:B:W339	17.08	Yes	Yes	0	7	9
652	B:B:H311	B:B:V315	5.54	Yes	No	0	9	7
653	B:B:H311	B:B:T329	8.21	Yes	No	0	9	8
654	B:B:G330	B:B:H311	3.18	No	Yes	0	5	9
655	B:B:H311	B:B:S331	16.74	Yes	No	7	9	9
656	B:B:D333	B:B:H311	10.08	Yes	Yes	7	9	9
657	B:B:H311	B:B:K337	11.79	Yes	Yes	7	9	6
658	B:B:D312	B:B:D333	3.99	No	Yes	0	5	9
659	B:B:D312	R:R:H315	8.82	No	No	0	5	4
660	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
661	B:B:R314	B:B:W332	22.99	No	Yes	1	8	9
662	B:B:C317	B:B:S316	3.44	No	No	0	7	9
663	B:B:S316	B:B:W332	6.18	No	Yes	0	9	9
664	B:B:L318	B:B:V327	2.98	Yes	Yes	7	6	6
665	B:B:L318	B:B:T329	2.95	Yes	No	0	6	8
666	B:B:V320	B:B:V327	3.21	No	Yes	0	7	6
667	B:B:D323	B:B:T321	8.67	No	No	4	7	7
668	B:B:D323	B:B:M325	9.7	No	No	0	7	5
669	B:B:G324	G:G:P49	4.06	No	No	0	9	7
670	B:B:M325	G:G:P49	6.71	No	No	0	5	7
671	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
672	B:B:V327	B:B:W339	3.68	Yes	Yes	7	6	9
673	B:B:T329	B:B:W339	9.7	No	Yes	0	8	9
674	B:B:D333	B:B:S331	8.83	Yes	No	7	9	9
675	B:B:D333	B:B:F335	10.75	Yes	Yes	7	9	4
676	B:B:F335	B:B:S334	6.61	Yes	No	0	4	4
677	B:B:F335	R:R:K67	6.2	Yes	No	7	4	6
678	B:B:K337	B:B:W339	6.96	Yes	Yes	7	6	9
679	B:B:I338	G:G:F61	6.28	Yes	Yes	4	5	8
680	B:B:N340	G:G:N59	10.9	No	Yes	4	9	9
681	B:B:N340	G:G:F61	4.83	No	Yes	4	9	8
682	G:G:E17	G:G:R13	27.91	No	No	0	6	6
683	G:G:E17	G:G:K14	8.1	No	No	0	6	4
684	G:G:E22	G:G:Q18	3.82	No	No	0	9	9
685	G:G:A23	G:G:K20	3.21	No	No	0	8	6
686	G:G:K20	G:G:N24	12.59	No	No	0	6	1
687	G:G:I25	G:G:R27	12.53	No	Yes	0	2	8
688	G:G:A33	G:G:I28	3.25	No	No	0	7	4
689	G:G:D36	G:G:K32	9.68	No	No	0	5	5
690	G:G:E42	G:G:M38	6.77	No	No	8	1	4
691	G:G:H44	G:G:Y40	17.42	No	Yes	0	6	6
692	G:G:A43	G:G:H44	2.93	No	No	0	4	6
693	G:G:E47	G:G:H44	6.15	No	No	0	3	6
694	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
695	G:G:D48	G:G:L51	9.5	Yes	Yes	8	9	6
696	G:G:P55	G:G:V54	3.53	No	No	0	5	6
697	G:G:N59	G:G:V54	2.96	Yes	No	0	9	6
698	G:G:N59	G:G:P60	4.89	Yes	No	0	9	9
699	R:R:F36	R:R:F40	4.29	No	Yes	0	4	5
700	R:R:F36	R:R:K282	9.93	No	No	0	4	2
701	R:R:L41	R:R:N37	5.49	Yes	No	0	6	3
702	R:R:I39	R:R:T43	3.04	No	No	0	5	4
703	R:R:F40	R:R:I44	16.33	Yes	No	0	5	5
704	R:R:F40	R:R:I286	5.02	Yes	No	0	5	6
705	R:R:L41	R:R:P42	3.28	Yes	No	0	6	5
706	R:R:L41	R:R:Y45	5.86	Yes	Yes	0	6	7
707	R:R:A98	R:R:P42	3.74	No	No	0	5	5
708	R:R:P42	R:R:V99	3.53	No	No	0	5	4
709	R:R:E288	R:R:Y45	4.49	No	Yes	2	5	7
710	R:R:F292	R:R:Y45	10.32	Yes	Yes	2	7	7
711	R:R:F293	R:R:I48	12.56	No	No	22	5	7
712	R:R:C296	R:R:I48	6.55	No	No	22	7	7
713	R:R:F49	R:R:V88	3.93	No	Yes	0	6	6
714	R:R:F49	R:R:P92	8.67	No	No	0	6	9
715	R:R:C296	R:R:T51	3.38	No	No	0	7	5
716	R:R:G52	R:R:V88	3.68	No	Yes	0	8	6
717	R:R:I53	R:R:V88	3.07	No	Yes	0	5	6
718	R:R:G55	R:R:V54	3.68	No	No	0	8	4
719	R:R:L58	R:R:V54	2.98	No	No	0	5	4
720	R:R:G55	R:R:P299	4.06	No	No	0	8	9
721	R:R:F304	R:R:G55	3.01	Yes	No	0	6	8
722	R:R:N56	R:R:S81	2.98	No	No	0	9	9
723	R:R:D84	R:R:N56	12.12	Yes	No	0	9	9
724	R:R:N56	R:R:P299	13.03	No	No	0	9	9
725	R:R:F304	R:R:L58	3.65	Yes	No	0	6	5
726	R:R:S81	R:R:V59	8.08	No	No	0	9	8
727	R:R:A303	R:R:V59	5.09	No	No	11	7	8
728	R:R:F309	R:R:V59	5.24	Yes	No	11	8	8
729	R:R:I60	R:R:S81	4.64	No	No	0	7	9
730	R:R:F309	R:R:V62	7.87	Yes	No	0	8	7
731	R:R:S312	R:R:V62	3.23	No	No	0	6	7
732	R:R:A313	R:R:V62	3.39	No	No	0	5	7
733	R:R:M63	R:R:R70	6.2	No	Yes	11	6	6
734	R:R:D74	R:R:M63	8.32	Yes	No	11	8	6
735	R:R:M63	R:R:R77	6.2	No	Yes	11	6	8
736	R:R:K68	R:R:Q66	5.42	No	Yes	0	6	4
737	R:R:Q66	R:R:R70	3.5	Yes	Yes	11	4	6
738	R:R:D74	R:R:Q66	6.53	Yes	Yes	11	8	4
739	R:R:Q66	R:R:S312	4.33	Yes	No	0	4	6
740	R:R:D74	R:R:R70	3.57	Yes	Yes	11	8	6
741	R:R:L78	R:R:R70	6.07	No	Yes	0	5	6
742	R:R:S71	R:R:T73	4.8	No	No	0	7	7
743	R:R:D74	R:R:S71	8.83	Yes	No	0	8	7
744	R:R:K75	R:R:M72	4.32	No	No	0	6	6
745	R:R:M72	R:R:R148	4.96	No	Yes	0	6	6
746	R:R:D74	R:R:R77	3.57	Yes	Yes	11	8	8
747	R:R:E153	R:R:K75	8.1	No	No	0	7	6
748	R:R:F129	R:R:Y76	8.25	Yes	Yes	2	5	7
749	R:R:I130	R:R:Y76	6.04	Yes	Yes	2	8	7
750	R:R:D133	R:R:Y76	10.34	No	Yes	0	8	7
751	R:R:L151	R:R:Y76	3.52	Yes	Yes	2	4	7
752	R:R:A152	R:R:Y76	4	No	Yes	0	3	7
753	R:R:V156	R:R:Y76	3.79	Yes	Yes	2	5	7
754	R:R:A303	R:R:R77	4.15	No	Yes	11	7	8
755	R:R:F309	R:R:R77	9.62	Yes	Yes	11	8	8
756	R:R:L78	W:W:?1	13.9	No	Yes	0	5	0
757	R:R:H79	R:R:I126	3.98	Yes	Yes	0	9	7
758	R:R:H79	R:R:V156	9.69	Yes	Yes	2	9	5
759	R:R:H79	R:R:Y157	7.62	Yes	No	2	9	7
760	R:R:H79	R:R:W161	7.41	Yes	Yes	2	9	9
761	R:R:H79	W:W:?1	20.65	Yes	Yes	2	9	0
762	R:R:D84	R:R:L80	4.07	Yes	Yes	2	9	9
763	R:R:I126	R:R:L80	5.71	Yes	Yes	0	7	9
764	R:R:L127	R:R:L80	5.54	No	Yes	2	8	9
765	R:R:L80	R:R:N298	8.24	Yes	Yes	2	9	9
766	R:R:L80	R:R:Y302	3.52	Yes	Yes	2	9	9
767	R:R:V82	W:W:?1	4.49	No	Yes	0	5	0
768	R:R:A83	R:R:S122	3.42	No	No	0	8	7
769	R:R:D84	R:R:S123	4.42	Yes	No	0	9	9
770	R:R:C295	R:R:D84	4.67	Yes	Yes	2	9	9
771	R:R:D84	R:R:N298	8.08	Yes	Yes	2	9	9
772	R:R:F87	R:R:L91	4.87	Yes	No	0	7	8
773	R:R:F87	R:R:Y116	6.19	Yes	Yes	2	7	6
774	R:R:F87	R:R:S119	9.25	Yes	No	0	7	8
775	R:R:F87	R:R:L120	4.87	Yes	Yes	2	7	7
776	R:R:F292	R:R:F87	13.93	Yes	Yes	2	7	7
777	R:R:F87	R:R:H294	6.79	Yes	Yes	2	7	9
778	R:R:C295	R:R:F87	6.98	Yes	Yes	2	9	7
779	R:R:C295	R:R:V88	3.42	Yes	Yes	0	9	6
780	R:R:T90	R:R:W94	6.06	No	No	2	6	7
781	R:R:I115	R:R:T90	3.04	No	No	0	5	6
782	R:R:T90	R:R:Y116	4.99	No	Yes	2	6	6
783	R:R:F93	R:R:W102	8.02	Yes	Yes	12	6	9
784	R:R:F104	R:R:F93	5.36	Yes	Yes	12	7	6
785	R:R:F93	R:R:L108	8.53	Yes	Yes	12	6	5
786	R:R:F93	R:R:V112	11.8	Yes	No	12	6	5
787	R:R:H113	R:R:W94	9.52	Yes	No	0	6	7
788	R:R:W94	R:R:Y116	5.79	No	Yes	2	7	6
789	R:R:F104	R:R:V96	6.55	Yes	No	0	7	5
790	R:R:D97	R:R:N101	5.39	No	No	0	5	4
791	R:R:D97	R:R:W102	3.35	No	Yes	0	5	9
792	R:R:N101	R:R:R183	13.26	No	No	0	4	3
793	R:R:I185	R:R:N101	5.66	No	No	0	3	4
794	R:R:F104	R:R:W102	20.04	Yes	Yes	12	7	9
795	R:R:L108	R:R:W102	4.56	Yes	Yes	12	5	9
796	R:R:C109	R:R:W102	9.14	No	Yes	12	9	9
797	R:R:C186	R:R:W102	14.37	No	Yes	12	9	9
798	R:R:F104	R:R:Y103	4.13	Yes	No	0	7	3
799	R:R:F104	R:R:L108	6.09	Yes	Yes	12	7	5
800	R:R:K110	R:R:N106	5.6	No	No	23	7	3
801	R:R:N106	R:R:N176	5.45	No	No	23	3	4
802	R:R:N106	R:R:V177	7.39	No	No	0	3	4
803	R:R:L108	R:R:V112	2.98	Yes	No	12	5	5
804	R:R:C109	R:R:H113	2.95	No	Yes	0	9	6
805	R:R:C109	R:R:C186	7.28	No	No	12	9	9
806	R:R:A175	R:R:K110	3.21	No	No	0	4	7
807	R:R:K110	R:R:N176	5.6	No	No	23	7	4
808	R:R:D171	R:R:H113	10.08	Yes	Yes	0	4	6
809	R:R:A175	R:R:H113	4.39	No	Yes	0	4	6
810	R:R:T168	R:R:V114	7.93	Yes	No	0	6	5
811	R:R:D171	R:R:V114	4.38	Yes	No	0	4	5
812	R:R:F172	R:R:V114	11.8	No	No	0	4	5
813	R:R:L120	R:R:Y116	4.69	Yes	Yes	2	7	6
814	R:R:F292	R:R:Y116	4.13	Yes	Yes	2	7	6
815	R:R:T117	R:R:T168	3.14	No	Yes	0	5	6
816	R:R:D171	R:R:T117	5.78	Yes	No	0	4	5
817	R:R:T168	R:R:V118	4.76	Yes	No	0	6	5
818	R:R:L120	R:R:Y121	4.69	Yes	Yes	2	7	7
819	R:R:H203	R:R:L120	3.86	Yes	Yes	2	4	7
820	R:R:L120	R:R:W252	4.56	Yes	Yes	0	7	9
821	R:R:L167	R:R:Y121	9.38	No	Yes	2	5	7
822	R:R:Q202	R:R:Y121	3.38	No	Yes	2	3	7
823	R:R:H203	R:R:Y121	8.71	Yes	Yes	2	4	7
824	R:R:V206	R:R:Y121	10.09	No	Yes	2	4	7
825	R:R:S122	R:R:W161	8.65	No	Yes	0	7	9
826	R:R:H294	R:R:S123	5.58	Yes	No	0	9	9
827	R:R:P211	R:R:V124	5.3	Yes	No	0	9	7
828	R:R:V124	R:R:W252	3.68	No	Yes	0	7	9
829	R:R:L125	R:R:V160	4.47	No	Yes	0	5	7
830	R:R:L125	R:R:P211	3.28	No	Yes	0	5	9
831	R:R:I126	R:R:I130	2.94	Yes	Yes	0	7	8
832	R:R:I126	R:R:V160	4.61	Yes	Yes	0	7	7
833	R:R:L127	R:R:N298	6.87	No	Yes	2	8	9
834	R:R:L127	R:R:Y302	10.55	No	Yes	2	8	9
835	R:R:A128	R:R:V214	3.39	No	No	0	7	6
836	R:R:F129	R:R:L151	3.65	Yes	Yes	2	5	4
837	R:R:F129	R:R:V155	5.24	Yes	No	2	5	2
838	R:R:F129	R:R:V156	3.93	Yes	Yes	2	5	5
839	R:R:F129	R:R:V160	6.55	Yes	Yes	2	5	7
840	R:R:I130	R:R:R134	6.26	Yes	Yes	2	8	9
841	R:R:I130	R:R:Y302	6.04	Yes	Yes	2	8	9
842	R:R:I215	R:R:S131	7.74	No	No	0	7	9
843	R:R:C218	R:R:S131	5.16	No	No	0	6	9
844	R:R:S131	R:R:Y219	13.99	No	Yes	0	9	8
845	R:R:L132	R:R:L151	5.54	No	Yes	0	6	4
846	R:R:D133	R:R:R148	14.29	No	Yes	0	8	6
847	R:R:R134	R:R:Y219	10.29	Yes	Yes	2	9	8
848	R:R:L244	R:R:R134	3.64	Yes	Yes	2	7	9
849	R:R:R134	R:R:Y302	7.2	Yes	Yes	2	9	9
850	R:R:V139	R:R:Y135	12.62	No	Yes	24	7	8
851	R:R:H140	R:R:Y135	7.62	No	Yes	24	6	8
852	R:R:C218	R:R:Y135	4.03	No	Yes	0	6	8
853	R:R:I221	R:R:Y135	6.04	No	Yes	0	4	8
854	R:R:L136	R:R:S144	4.5	No	No	0	5	5
855	R:R:L136	R:R:R148	4.86	No	Yes	0	5	6
856	R:R:A137	R:R:R148	6.91	No	Yes	0	8	6
857	R:R:I138	R:R:I222	2.94	No	No	0	8	8
858	R:R:H140	R:R:V139	11.07	No	No	24	6	7
859	R:R:K225	R:R:V139	4.55	No	No	0	4	7
860	R:R:H140	R:R:N143	3.83	No	No	0	6	5
861	R:R:L151	R:R:V155	4.47	Yes	No	2	4	2
862	R:R:A152	R:R:E153	3.02	No	No	0	3	7
863	R:R:V156	R:R:Y157	6.31	Yes	No	2	5	7
864	R:R:V156	R:R:V160	3.21	Yes	Yes	2	5	7
865	R:R:Y157	W:W:?1	9.42	No	Yes	2	7	0
866	R:R:G159	R:R:P163	4.06	No	No	0	3	4
867	R:R:V160	R:R:W161	7.36	Yes	Yes	2	7	9
868	R:R:W161	W:W:?1	19.44	Yes	Yes	2	9	0
869	R:R:I162	R:R:P163	3.39	No	No	0	4	4
870	R:R:L165	R:R:T168	2.95	No	Yes	0	3	6
871	R:R:L167	R:R:Q202	3.99	No	No	2	5	3
872	R:R:L167	R:R:V206	4.47	No	No	2	5	4
873	R:R:I169	R:R:P170	3.39	No	No	0	3	8
874	R:R:F199	R:R:P170	5.78	Yes	No	0	5	8
875	R:R:D171	R:R:R188	5.96	Yes	No	0	4	5
876	R:R:F174	R:R:I173	8.79	Yes	No	0	4	3
877	R:R:F174	R:R:Y190	8.25	Yes	Yes	2	4	4
878	R:R:F174	R:R:P191	4.33	Yes	Yes	2	4	5
879	R:R:F174	R:R:W195	7.02	Yes	Yes	2	4	5
880	R:R:C186	R:R:V177	6.83	No	No	0	9	4
881	R:R:F189	R:R:S178	6.61	No	No	0	3	1
882	R:R:D181	R:R:D182	6.65	No	No	0	2	6
883	R:R:D187	R:R:F189	14.33	No	No	0	3	3
884	R:R:R188	R:R:Y190	14.4	No	Yes	2	5	4
885	R:R:F199	R:R:R188	4.28	Yes	No	2	5	5
886	R:R:P191	R:R:Y190	4.17	Yes	Yes	2	5	4
887	R:R:V196	R:R:Y190	6.31	No	Yes	0	4	4
888	R:R:F199	R:R:Y190	11.35	Yes	Yes	2	5	4
889	R:R:N192	R:R:P191	3.26	No	Yes	2	1	5
890	R:R:P191	R:R:W195	8.11	Yes	Yes	2	5	5
891	R:R:L194	R:R:N192	4.12	No	No	0	2	1
892	R:R:N192	R:R:W195	6.78	No	Yes	2	1	5
893	R:R:F199	R:R:W195	7.02	Yes	Yes	2	5	5
894	R:R:L266	R:R:V196	2.98	No	No	0	3	4
895	R:R:F201	R:R:V197	3.93	No	No	0	4	3
896	R:R:L266	R:R:V197	2.98	No	No	0	3	3
897	R:R:L267	R:R:V197	8.94	No	No	0	1	3
898	R:R:F199	R:R:Q202	3.51	Yes	No	2	5	3
899	R:R:I259	R:R:Q200	5.49	No	No	0	5	5
900	R:R:D262	R:R:Q200	6.53	No	No	0	5	5
901	R:R:Q200	R:R:S263	10.11	No	No	0	5	5
902	R:R:F201	R:R:S263	6.61	No	No	0	4	5
903	R:R:H203	R:R:Y255	3.27	Yes	Yes	2	4	7
904	R:R:H203	R:R:Y256	13.07	Yes	Yes	2	4	8
905	R:R:I204	R:R:Y256	3.63	Yes	Yes	0	5	8
906	R:R:I204	R:R:I259	5.89	Yes	No	0	5	5
907	R:R:I204	R:R:S260	4.64	Yes	No	0	5	5
908	R:R:I209	R:R:M205	4.37	No	No	0	4	4
909	R:R:G207	R:R:V206	3.68	No	No	0	5	4
910	R:R:L208	R:R:Y256	12.89	No	Yes	0	8	8
911	R:R:I209	R:R:I213	2.94	No	No	0	4	3
912	R:R:L210	R:R:P211	3.28	No	Yes	0	6	9
913	R:R:F248	R:R:G212	3.01	Yes	No	25	9	6
914	R:R:F249	R:R:G212	3.01	No	No	25	4	6
915	R:R:F248	R:R:I215	7.54	Yes	No	0	9	7
916	R:R:C220	R:R:L216	3.17	No	No	0	3	4
917	R:R:F249	R:R:L216	10.96	No	No	0	4	4
918	R:R:T241	R:R:Y219	6.24	Yes	Yes	0	7	8
919	R:R:L244	R:R:Y219	4.69	Yes	Yes	2	7	8
920	R:R:I245	R:R:Y219	6.04	No	Yes	0	7	8
921	R:R:Y219	R:R:Y302	2.98	Yes	Yes	2	8	9
922	R:R:I222	R:R:T241	3.04	No	Yes	0	8	7
923	R:R:I223	R:R:T241	6.08	No	Yes	0	4	7
924	R:R:I223	R:R:V242	3.07	No	No	0	4	4
925	R:R:K225	R:R:S224	4.59	No	No	0	4	4
926	R:R:H228	R:R:S229	5.58	No	No	0	5	5
927	R:R:K234	R:R:S229	12.24	No	No	0	7	5
928	R:R:H232	R:R:R235	3.39	No	No	0	4	5
929	R:R:H232	R:R:K236	15.72	No	No	0	4	8
930	R:R:K236	R:R:K239	4.31	No	No	0	8	6
931	R:R:L246	R:R:V242	2.98	No	No	0	5	4
932	R:R:L244	R:R:L301	4.15	Yes	Yes	0	7	7
933	R:R:L244	R:R:Y302	5.86	Yes	Yes	2	7	9
934	R:R:F248	R:R:F249	10.72	Yes	No	25	9	4
935	R:R:F248	R:R:W252	7.02	Yes	Yes	0	9	9
936	R:R:C251	R:R:W252	3.92	No	Yes	0	8	9
937	R:R:W252	R:R:Y256	9.65	Yes	Yes	0	9	8
938	R:R:A291	R:R:W252	5.19	No	Yes	0	8	9
939	R:R:H294	R:R:W252	15.87	Yes	Yes	0	9	9
940	R:R:P254	R:R:T287	5.25	No	No	0	9	6
941	R:R:Y255	R:R:Y256	5.96	Yes	Yes	2	7	8
942	R:R:I259	R:R:Y255	10.88	No	Yes	0	5	7
943	R:R:T287	R:R:Y255	3.75	No	Yes	0	6	7
944	R:R:E288	R:R:Y255	11.22	No	Yes	2	5	7
945	R:R:A291	R:R:Y255	4	No	Yes	0	8	7
946	R:R:G258	R:R:I284	3.53	No	No	0	4	4
947	R:R:I261	R:R:V280	6.14	No	No	0	5	5
948	R:R:D262	R:R:H281	8.82	No	No	0	5	4
949	R:R:D262	R:R:I284	4.2	No	No	0	5	4
950	R:R:F264	R:R:I269	5.02	No	No	0	4	1
951	R:R:I265	R:R:I270	2.94	No	No	0	3	5
952	R:R:E277	R:R:I265	5.47	No	No	0	2	3
953	R:R:I265	R:R:V280	4.61	No	No	0	3	5
954	R:R:E268	R:R:K271	5.4	No	No	0	2	3
955	R:R:F276	R:R:I270	3.77	Yes	No	0	1	5
956	R:R:F276	R:R:Q272	8.2	Yes	No	0	1	2
957	R:R:F276	R:R:V280	3.93	Yes	No	0	1	5
958	R:R:K282	R:R:S285	3.06	No	No	0	2	5
959	R:R:T287	R:R:W283	10.92	No	No	0	6	6
960	R:R:E288	R:R:F292	10.49	No	Yes	2	5	7
961	R:R:C296	R:R:F293	4.19	No	No	22	7	5
962	R:R:C295	R:R:H294	7.37	Yes	Yes	2	9	9
963	R:R:N298	R:R:Y302	3.49	Yes	Yes	2	9	9
964	R:R:A303	R:R:F309	8.32	No	Yes	11	7	8
965	R:R:F304	R:R:F309	5.36	Yes	Yes	0	6	8
966	R:R:H315	R:R:T311	5.48	No	No	0	4	4
967	A:A:I19	A:A:M18	2.92	No	No	0	9	4
968	R:R:K149	R:R:M72	2.88	No	No	0	6	6
969	R:R:I48	R:R:L91	2.85	No	No	0	7	8
970	R:R:I169	R:R:L166	2.85	No	No	0	3	4
971	R:R:I222	R:R:L226	2.85	No	No	0	8	8
972	R:R:I223	R:R:L238	2.85	No	No	0	4	5
973	B:B:Q175	B:B:T173	2.83	No	No	0	4	5
974	B:B:K15	G:G:L19	2.82	No	No	0	6	9
975	R:R:K154	R:R:L150	2.82	No	No	0	3	4
976	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
977	B:B:G310	B:B:W339	2.81	No	Yes	0	5	9
978	B:B:D27	G:G:K29	2.77	No	No	0	8	4
979	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
980	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
981	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
982	B:B:A299	B:B:F278	2.77	No	Yes	0	5	7
983	R:R:L208	R:R:L253	2.77	No	No	0	8	5
984	R:R:L297	R:R:L301	2.77	No	Yes	0	6	7
985	R:R:D193	R:R:L266	2.71	No	No	0	1	3
986	A:A:E43	A:A:K270	2.7	Yes	Yes	0	9	9
987	R:R:A95	R:R:Y45	2.67	No	Yes	0	7	7
988	R:R:A289	R:R:Y45	2.67	No	Yes	0	4	7
989	A:A:E276	A:A:L273	2.65	No	Yes	0	5	6
990	A:A:R208	A:A:S252	2.64	Yes	No	0	9	7
991	G:G:R13	G:G:V16	2.62	No	Yes	0	6	7
992	R:R:F276	R:R:T279	2.59	Yes	No	0	1	2
993	R:R:F304	R:R:I300	2.51	Yes	No	0	6	6
994	A:A:K29	A:A:R32	2.48	No	No	0	1	4
995	A:A:F199	A:A:K197	2.48	Yes	No	0	5	6
996	R:R:F40	R:R:L41	2.44	Yes	Yes	0	5	6
997	B:B:F292	B:B:N313	2.42	No	No	0	4	7
998	B:B:Q9	B:B:R8	2.34	No	No	0	3	3
999	B:B:E130	B:B:R129	2.33	No	No	0	3	3
1000	A:A:R15	B:B:H91	2.26	No	No	0	5	5
1001	R:R:E179	R:R:Y184	2.24	No	No	0	2	5
1002	A:A:G40	A:A:G45	2.11	No	No	0	9	9
1003	R:R:R183	R:R:Y184	2.06	No	No	0	3	5
1004	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
1005	A:A:A30	A:A:G27	1.95	No	No	0	3	5
1006	A:A:A41	A:A:G42	1.95	No	No	0	7	8
1007	A:A:A203	A:A:G183	1.95	No	No	0	9	9
1008	B:B:A140	B:B:G141	1.95	No	No	0	5	5
1009	B:B:A231	B:B:G244	1.95	No	No	0	5	5
1010	B:B:A193	B:B:P194	1.87	No	No	0	4	4
1011	R:R:A128	R:R:P211	1.87	No	Yes	0	7	9
1012	B:B:G77	B:B:S98	1.86	No	No	0	8	8
1013	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
1014	R:R:G159	R:R:V158	1.84	No	No	0	3	4
1015	B:B:G131	B:B:T128	1.82	No	No	0	4	3
1016	B:B:G185	B:B:T164	1.82	No	No	0	5	6
1017	B:B:G174	B:B:T173	1.82	No	No	0	4	5
1018	B:B:G182	B:B:T181	1.82	No	No	0	6	2
1019	B:B:G224	B:B:T223	1.82	No	No	0	6	2
1020	B:B:A60	B:B:C103	1.81	No	No	0	7	8
1021	R:R:G57	R:R:I60	1.76	No	No	0	3	7
1022	R:R:G258	R:R:I261	1.76	No	No	0	4	5
1023	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1024	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1025	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
1026	R:R:C218	R:R:S217	1.72	No	No	0	6	3
1027	A:A:G27	B:B:L55	1.71	No	No	0	5	6
1028	B:B:A28	G:G:S31	1.71	No	No	0	4	9
1029	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
1030	B:B:A11	G:G:V16	1.7	No	Yes	0	5	7
1031	R:R:A100	R:R:V99	1.7	No	No	0	5	4
1032	A:A:C325	A:A:T327	1.69	No	No	0	7	8
1033	A:A:A203	A:A:T202	1.68	No	Yes	0	9	9
1034	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
1035	R:R:L290	R:R:P254	1.64	No	No	0	7	9
1036	R:R:G273	R:R:Q272	1.64	No	No	0	5	2
1037	A:A:N294	A:A:P282	1.63	No	No	0	3	5
1038	A:A:I343	R:R:A141	1.62	Yes	No	0	7	8
1039	A:A:I344	R:R:A141	1.62	No	No	0	6	8
1040	B:B:A28	B:B:I33	1.62	No	No	0	4	3
1041	R:R:A180	R:R:I185	1.62	No	No	0	1	3
1042	A:A:A245	A:A:M240	1.61	No	Yes	0	9	6
1043	A:A:K349	R:R:A307	1.61	No	No	0	5	5
1044	B:B:D38	B:B:P39	1.61	No	No	0	1	1
1045	B:B:S31	B:B:T29	1.6	No	No	0	1	3
1046	A:A:T187	A:A:V50	1.59	No	No	0	6	6
1047	A:A:T187	A:A:V185	1.59	No	No	0	6	5
1048	B:B:A11	G:G:L19	1.58	No	No	0	5	9
1049	R:R:A111	R:R:L108	1.58	No	Yes	0	4	5
1050	R:R:A247	R:R:L301	1.58	No	Yes	0	6	7
1051	R:R:C274	R:R:N278	1.57	No	No	0	5	3
1052	A:A:A12	B:B:N88	1.56	No	Yes	0	4	7
1053	B:B:M262	B:B:S31	1.53	Yes	No	0	4	1
1054	R:R:I47	R:R:T51	1.52	No	No	0	4	5
1055	R:R:C274	R:R:E277	1.52	No	No	0	5	2
1056	A:A:A11	A:A:E8	1.51	No	No	0	4	5
1057	A:A:M198	A:A:T187	1.51	Yes	No	0	7	6
1058	A:A:A235	A:A:E236	1.51	No	No	0	4	9
1059	A:A:F354	A:A:G352	1.51	Yes	No	0	5	8
1060	A:A:F354	R:R:G306	1.51	Yes	No	0	5	8
1061	R:R:F104	R:R:G105	1.51	Yes	No	0	7	8
1062	R:R:F129	R:R:G159	1.51	Yes	No	0	5	3
1063	A:A:K51	A:A:T48	1.5	No	No	0	9	9
1064	G:G:K46	G:G:T52	1.5	No	No	0	1	4
1065	R:R:G64	R:R:R70	1.5	No	Yes	0	2	6
1066	R:R:L86	R:R:S119	1.5	No	No	0	7	8
1067	R:R:L238	R:R:S227	1.5	No	No	0	5	4
1068	R:R:K239	R:R:T240	1.5	No	No	0	6	7
1069	A:A:D9	A:A:S6	1.47	No	No	0	4	7
1070	R:R:I204	R:R:I209	1.47	Yes	No	0	5	4
1071	R:R:I257	R:R:I261	1.47	No	No	0	6	5
1072	R:R:I269	R:R:I270	1.47	No	No	0	1	5
1073	A:A:D9	A:A:V13	1.46	No	No	0	4	3
1074	A:A:D328	A:A:T327	1.45	No	No	0	9	8
1075	R:R:K308	R:R:K68	1.44	No	No	0	6	6
1076	R:R:P147	R:R:R146	1.44	No	No	0	4	5
1077	A:A:E238	A:A:V233	1.43	No	No	0	4	5
1078	R:R:I53	R:R:L85	1.43	No	No	0	5	7
1079	R:R:I89	R:R:L86	1.43	No	No	0	4	7
1080	R:R:I243	R:R:L301	1.43	No	Yes	0	5	7
1081	R:R:I300	R:R:L305	1.43	No	No	0	6	6
1082	G:G:D26	G:G:I25	1.4	No	No	0	1	2
1083	B:B:C25	G:G:R27	1.39	No	Yes	0	3	8
1084	A:A:D309	A:A:K314	1.38	No	No	0	4	3
1085	B:B:A11	B:B:R8	1.38	No	No	0	5	3
1086	B:B:D303	B:B:K301	1.38	No	Yes	0	2	5
1087	A:A:D272	A:A:L273	1.36	No	Yes	0	9	6
1088	B:B:D76	B:B:L55	1.36	Yes	No	0	9	6
1089	A:A:E33	A:A:K29	1.35	No	No	0	6	1
1090	A:A:D193	R:R:N143	1.35	No	No	0	3	5
1091	R:R:E153	R:R:K154	1.35	No	No	0	7	3
1092	R:R:A316	R:R:Y65	1.33	No	No	0	5	5
1093	R:R:A164	R:R:Y121	1.33	No	Yes	0	7	7
1094	A:A:H244	A:A:M240	1.31	Yes	Yes	0	4	6
1095	R:R:F199	R:R:V198	1.31	Yes	No	0	5	3
1096	A:A:D26	A:A:E25	1.3	No	No	0	5	4
1097	A:A:D237	A:A:E239	1.3	No	No	0	8	4
1098	B:B:Q13	B:B:Q9	1.28	No	No	0	1	3
1099	R:R:D187	R:R:H113	1.26	No	Yes	0	3	6
1100	R:R:F49	R:R:L50	1.22	No	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:V34	6.2	5	9	5
2	A:A:L37	6.5275	4	0	9
3	A:A:E43	4.1825	4	0	9
4	A:A:F189	8.4225	4	0	9
5	A:A:F191	9.935	4	9	5
6	A:A:L194	5.9425	4	9	4
7	A:A:F196	7.635	6	9	7
8	A:A:M198	6.4825	4	0	7
9	A:A:F199	7.10833	6	1	5
10	A:A:T202	5.5975	4	18	9
11	A:A:Q204	6.5175	4	1	9
12	A:A:S206	5.39	4	1	8
13	A:A:R208	4.06	5	1	9
14	A:A:K210	6.24143	7	1	9
15	A:A:W211	5.20875	8	1	9
16	A:A:I212	4.7625	4	1	8
17	A:A:H213	7.9425	4	1	8
18	A:A:C214	3.6375	4	1	7
19	A:A:F215	8.25	4	1	9
20	A:A:I222	4.405	4	17	7
21	A:A:V225	5.6675	4	3	7
22	A:A:Y230	6.928	5	3	8
23	A:A:D231	6.57	5	3	9
24	A:A:M240	2.83	4	0	6
25	A:A:M243	3.555	4	3	8
26	A:A:H244	7.67	4	3	4
27	A:A:F250	7.662	5	0	9
28	A:A:W258	9.41833	6	1	5
29	A:A:F259	5.9575	4	1	9
30	A:A:I265	3.6725	4	0	8
31	A:A:F267	4.614	5	19	9
32	A:A:L268	6.0775	4	0	8
33	A:A:K270	4.4675	4	3	9
34	A:A:L273	4.3125	4	3	6
35	A:A:F274	5.405	4	3	9
36	A:A:L283	6.6375	4	3	7
37	A:A:C286	8.295	4	3	6
38	A:A:Y287	9.74714	7	3	7
39	A:A:Y290	9.018	5	3	7
40	A:A:Y296	6.455	6	0	4
41	A:A:Y302	14.665	4	3	6
42	A:A:F307	7.095	6	3	8
43	A:A:N311	5.7425	4	13	8
44	A:A:K317	5.7475	4	13	7
45	A:A:Y320	8.14833	6	14	7
46	A:A:T321	9.335	4	20	5
47	A:A:H322	10.295	4	19	9
48	A:A:Q333	6.5675	4	9	5
49	A:A:F336	5.90857	7	9	8
50	A:A:I343	2.995	4	0	7
51	A:A:K345	5.32	4	14	5
52	A:A:F354	6.614	5	0	5
53	B:B:I37	4.19333	6	8	2
54	B:B:V40	4.868	5	8	3
55	B:B:R48	4.5125	4	4	7
56	B:B:L51	7.92	4	4	9
57	B:B:H54	8.84333	6	4	9
58	B:B:Y59	8.984	5	1	8
59	B:B:W63	6.04714	7	4	7
60	B:B:L70	5.2025	4	4	5
61	B:B:V71	4.22	5	10	8
62	B:B:D76	5.324	5	4	9
63	B:B:L79	4.6625	4	10	7
64	B:B:I80	9.585	4	4	8
65	B:B:I81	4.975	4	10	7
66	B:B:W82	8.93429	7	4	9
67	B:B:S84	4.39	4	4	5
68	B:B:N88	6.665	4	0	7
69	B:B:K89	6.055	6	4	9
70	B:B:I93	5.722	5	0	7
71	B:B:W99	7.3825	8	1	9
72	B:B:Y105	4.52167	6	10	6
73	B:B:N110	7.8275	4	1	4
74	B:B:Y111	7.304	5	1	4
75	B:B:V112	4.564	5	10	8
76	B:B:L117	4.0675	4	1	9
77	B:B:C121	3.7375	4	1	8
78	B:B:I123	4.2425	4	1	6
79	B:B:Y124	6.166	5	0	6
80	B:B:L139	7.2425	4	0	9
81	B:B:H142	7.528	5	1	9
82	B:B:Y145	7.17333	9	1	8
83	B:B:C149	3.368	5	1	8
84	B:B:F151	5.14833	6	1	9
85	B:B:I157	5.055	4	1	7
86	B:B:V158	4.29	4	5	5
87	B:B:T159	5.842	5	1	9
88	B:B:S160	5.2	4	5	6
89	B:B:D163	7.424	5	1	9
90	B:B:L168	4.285	4	5	6
91	B:B:W169	9.53667	6	1	8
92	B:B:Q176	7.61	4	1	4
93	B:B:F180	9.67	4	5	7
94	B:B:H183	7.97667	6	5	9
95	B:B:D186	5.8075	4	1	9
96	B:B:V187	5.024	5	5	9
97	B:B:L190	4.935	4	5	5
98	B:B:F199	7.34333	6	5	9
99	B:B:V200	7.255	4	6	6
100	B:B:S201	5.2625	4	5	9
101	B:B:C204	5.122	5	1	7
102	B:B:D205	5.265	4	5	9
103	B:B:K209	10.58	4	5	6
104	B:B:L210	4.836	5	0	5
105	B:B:W211	8.93333	6	5	8
106	B:B:Q220	7.3875	4	0	7
107	B:B:H225	8.61	6	6	9
108	B:B:D228	7.555	4	1	9
109	B:B:I232	5.8625	4	6	8
110	B:B:F235	6.7275	8	15	6
111	B:B:P236	6.725	4	15	7
112	B:B:F241	8.062	5	6	6
113	B:B:T243	6.6575	4	6	8
114	B:B:D246	7.55	4	1	9
115	B:B:D247	8.552	5	6	9
116	B:B:T249	5.9025	4	6	6
117	B:B:R251	12.7425	4	6	8
118	B:B:F253	9.03	4	6	6
119	B:B:M262	5.65	4	0	4
120	B:B:T263	6.23	4	6	1
121	B:B:Y264	6.422	5	0	5
122	B:B:F278	6.446	5	15	7
123	B:B:R283	9.578	5	8	9
124	B:B:L284	5.4575	4	0	5
125	B:B:Y289	7.89667	6	16	7
126	B:B:N295	6.7525	4	16	6
127	B:B:V296	4.645	4	0	5
128	B:B:W297	7.4975	4	16	8
129	B:B:K301	6.05	5	8	5
130	B:B:L308	9.18	4	0	7
131	B:B:H311	9.25667	6	7	9
132	B:B:L318	3.852	5	7	6
133	B:B:V327	3.2125	4	7	6
134	B:B:W332	11.0143	7	1	9
135	B:B:D333	8.4125	4	7	9
136	B:B:F335	7.4925	4	7	4
137	B:B:K337	8.8175	4	7	6
138	B:B:I338	4.7725	4	4	5
139	B:B:W339	7.31167	6	7	9
140	G:G:V16	3.6075	4	0	7
141	G:G:R27	8.228	5	0	8
142	G:G:Y40	9.7425	4	15	6
143	G:G:D48	7.23	5	8	9
144	G:G:L51	5.384	5	8	6
145	G:G:N59	5.5925	4	4	9
146	G:G:F61	5.34143	7	4	8
147	R:R:F40	7.02	4	0	5
148	R:R:L41	4.2675	4	0	6
149	R:R:Y45	5.202	5	2	7
150	R:R:Q66	4.945	4	11	4
151	R:R:R70	4.168	5	11	6
152	R:R:D74	6.164	5	11	8
153	R:R:Y76	5.99	6	2	7
154	R:R:R77	5.885	4	11	8
155	R:R:H79	9.87	5	2	9
156	R:R:L80	5.416	5	2	9
157	R:R:D84	6.672	5	2	9
158	R:R:F87	7.55429	7	2	7
159	R:R:V88	3.525	4	0	6
160	R:R:F93	8.4275	4	12	6
161	R:R:W102	9.91333	6	12	9
162	R:R:F104	7.28	6	12	7
163	R:R:L108	4.748	5	12	5
164	R:R:H113	5.64	5	0	6
165	R:R:Y116	5.158	5	2	6
166	R:R:L120	4.534	5	2	7
167	R:R:Y121	6.26333	6	2	7
168	R:R:I126	4.31	4	0	7
169	R:R:F129	4.855	6	2	5
170	R:R:I130	5.32	4	2	8
171	R:R:R134	6.88167	6	2	9
172	R:R:Y135	7.5775	4	24	8
173	R:R:R148	7.755	4	0	6
174	R:R:L151	4.295	4	2	4
175	R:R:V156	5.386	5	2	5
176	R:R:V160	5.24	5	2	7
177	R:R:W161	10.715	4	2	9
178	R:R:T168	4.695	4	0	6
179	R:R:D171	6.55	4	0	4
180	R:R:F174	7.0975	4	2	4
181	R:R:Y190	8.896	5	2	4
182	R:R:P191	4.9675	4	2	5
183	R:R:W195	7.2325	4	2	5
184	R:R:F199	5.54167	6	2	5
185	R:R:H203	7.2275	4	2	4
186	R:R:I204	3.9075	4	0	5
187	R:R:P211	3.4325	4	0	9
188	R:R:Y219	7.37167	6	2	8
189	R:R:T241	5.315	4	0	7
190	R:R:L244	4.585	4	2	7
191	R:R:F248	7.0725	4	25	9
192	R:R:W252	7.12714	7	0	9
193	R:R:Y255	6.51333	6	2	7
194	R:R:Y256	9.04	5	2	8
195	R:R:F276	4.6225	4	0	1
196	R:R:F292	9.7175	4	2	7
197	R:R:H294	8.9025	4	2	9
198	R:R:C295	5.61	4	2	9
199	R:R:N298	6.67	4	2	9
200	R:R:L301	2.4825	4	0	7
201	R:R:Y302	5.66286	7	2	9
202	R:R:F304	3.6325	4	0	6
203	R:R:F309	7.282	5	11	8
204	W:W:?1	13.58	5	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:M61	B:B:W63	20.8905	4.65	No	Yes	0	6	7
2	B:B:C317	B:B:M61	20.9588	4.86	No	No	0	7	6
3	B:B:C317	B:B:S316	21.0275	3.44	No	No	0	7	9
4	B:B:S316	B:B:W332	21.0965	6.18	No	Yes	0	9	9
5	A:A:W258	B:B:W332	15.4111	3.75	Yes	Yes	1	5	9
6	A:A:N256	A:A:W258	19.7002	10.17	No	Yes	1	8	5
7	A:A:F259	A:A:N256	17.8553	4.83	Yes	No	1	9	8
8	A:A:F259	A:A:I221	18.0273	8.79	Yes	No	1	9	8
9	A:A:I221	A:A:I264	18.1078	2.94	No	No	0	8	6
10	A:A:F250	A:A:I264	18.2732	3.77	Yes	No	0	9	6
11	A:A:F250	A:A:F307	58.5077	10.72	Yes	Yes	0	9	8
12	A:A:F307	A:A:M247	78.2851	8.71	Yes	No	0	8	6
13	A:A:M247	A:A:Y287	78.4333	8.38	No	Yes	0	6	7
14	A:A:L283	A:A:Y287	78.8109	7.03	Yes	Yes	3	7	7
15	A:A:L283	A:A:Y230	79.0142	5.86	Yes	Yes	3	7	8
16	A:A:K277	A:A:Y230	99.2308	7.17	No	Yes	3	9	8
17	A:A:K277	A:A:S228	99.5602	3.06	No	No	3	9	9
18	A:A:K270	A:A:S228	99.4502	6.12	Yes	No	3	9	9
19	A:A:E43	A:A:K270	99.7396	2.7	Yes	Yes	0	9	9
20	A:A:C224	A:A:E43	99.0706	4.56	No	Yes	0	7	9
21	A:A:C224	A:A:I49	98.6836	3.27	No	No	0	7	7
22	A:A:I49	A:A:L38	97.6297	4.28	No	No	17	7	8
23	A:A:L38	A:A:M198	100	12.72	No	Yes	0	8	7
24	A:A:L36	A:A:M198	66.4754	4.24	No	Yes	0	7	7
25	A:A:L36	A:A:V34	33.1513	2.98	No	Yes	9	7	5
26	A:A:V339	A:A:V34	33.0188	8.02	No	Yes	9	8	5
27	A:A:I343	A:A:V339	99.0229	3.07	Yes	No	0	7	8
28	A:A:I343	A:A:N347	98.8187	4.25	Yes	No	0	7	8
29	A:A:N347	R:R:A137	98.7114	4.69	No	No	0	8	8
30	R:R:A137	R:R:R148	98.6041	6.91	No	Yes	0	8	6
31	A:A:F196	A:A:L36	33.3133	6.09	Yes	No	9	7	7
32	A:A:F196	A:A:V339	66.1111	3.93	Yes	No	9	7	8
33	A:A:F189	A:A:M198	33.5413	7.46	Yes	Yes	0	9	7
34	A:A:F189	A:A:F196	33.343	16.08	Yes	Yes	0	9	7
35	A:A:F215	B:B:W99	12.9387	9.02	Yes	Yes	1	9	9
36	A:A:W211	B:B:L117	16.3936	3.42	Yes	Yes	1	9	9
37	A:A:A41	A:A:L249	39.7687	3.15	No	No	0	7	9
38	A:A:L249	A:A:R208	59.6006	3.64	No	Yes	0	9	9
39	A:A:A41	A:A:S246	39.9267	3.42	No	No	0	7	9
40	B:B:G162	B:B:Y145	13.7974	8.69	No	Yes	1	9	8
41	B:B:G162	B:B:S161	13.5819	3.71	No	No	1	9	9
42	A:A:W211	B:B:Y145	52.2426	5.79	Yes	Yes	1	9	8
43	A:A:K210	B:B:Y145	28.4205	3.58	Yes	Yes	1	9	8
44	A:A:I253	A:A:R208	19.9262	3.76	No	Yes	0	8	9
45	A:A:K210	B:B:D246	26.6647	5.53	Yes	Yes	1	9	9
46	A:A:F223	A:A:L249	19.9598	7.31	No	No	0	9	9
47	A:A:F223	A:A:I253	19.9594	6.28	No	No	0	9	8
48	A:A:S246	A:A:V225	19.9888	4.85	No	Yes	3	9	7
49	A:A:L268	A:A:V225	20.0886	2.98	Yes	Yes	0	8	7
50	A:A:L227	A:A:L268	20.0448	11.07	No	Yes	0	7	8
51	A:A:F274	A:A:L227	20.0636	7.31	Yes	No	0	9	7
52	R:R:D133	R:R:R148	97.4715	14.29	No	Yes	0	8	6
53	R:R:D133	R:R:Y76	97.364	10.34	No	Yes	0	8	7
54	R:R:I130	R:R:Y76	55.8333	6.04	Yes	Yes	2	8	7
55	R:R:V156	R:R:Y76	23.2067	3.79	Yes	Yes	2	5	7
56	R:R:I130	R:R:Y302	34.7256	6.04	Yes	Yes	2	8	9
57	B:B:D246	B:B:S227	26.4637	5.89	Yes	No	0	9	6
58	B:B:D247	B:B:S227	26.2435	2.94	Yes	No	0	9	6
59	B:B:D247	B:B:H225	24.2443	7.56	Yes	Yes	6	9	9
60	B:B:H225	B:B:T243	23.1391	8.21	Yes	Yes	6	9	8
61	B:B:F253	B:B:T243	17.5799	7.78	Yes	Yes	6	6	8
62	B:B:F222	B:B:F253	16.9228	10.72	No	Yes	6	8	6
63	B:B:F222	B:B:Q220	16.7071	7.03	No	Yes	0	8	7
64	B:B:D258	B:B:Q220	10.935	11.75	No	Yes	0	7	7
65	B:B:I18	G:G:A23	12.7245	3.25	No	No	0	7	8
66	G:G:A23	G:G:K20	11.3857	3.21	No	No	0	8	6
67	B:B:L14	G:G:K20	10.0468	5.64	No	No	0	8	6
68	B:B:T321	B:B:W63	14.7479	12.13	No	Yes	4	7	7
69	B:B:D323	B:B:T321	14.6017	8.67	No	No	4	7	7
70	B:B:D323	B:B:M325	14.5352	9.7	No	No	0	7	5
71	B:B:M325	G:G:P49	14.4647	6.71	No	No	0	5	7
72	G:G:D48	G:G:P49	14.2492	4.83	Yes	No	0	9	7
73	B:B:S97	B:B:W99	24.6257	4.94	No	Yes	0	8	9
74	B:B:D118	B:B:S97	24.2296	8.83	No	No	0	9	8
75	B:B:D118	B:B:I120	23.8335	4.2	No	No	0	9	6
76	B:B:E138	B:B:I120	23.4373	4.1	No	No	0	6	6
77	B:B:E138	B:B:S122	11.1233	7.19	No	No	0	6	8
78	B:B:S122	B:B:Y124	10.7266	6.36	No	Yes	0	8	6
79	B:B:E138	B:B:V135	11.9179	4.28	No	No	0	6	4
80	B:B:V135	B:B:Y124	10.7275	7.57	No	Yes	0	4	6
81	B:B:H142	B:B:S161	10.2343	13.95	Yes	No	1	9	9
82	B:B:S147	B:B:Y145	11.1393	3.82	No	Yes	0	9	8
83	B:B:S147	B:B:S160	10.9177	4.89	No	Yes	0	9	6
84	R:R:I126	R:R:I130	15.4346	2.94	Yes	Yes	0	7	8
85	R:R:I126	R:R:L80	15.3559	5.71	Yes	Yes	0	7	9
86	R:R:D84	R:R:L80	30.4442	4.07	Yes	Yes	2	9	9
87	R:R:C295	R:R:D84	39.1854	4.67	Yes	Yes	2	9	9
88	R:R:C295	R:R:F87	35.8086	6.98	Yes	Yes	2	9	7
89	R:R:L80	R:R:Y302	15.3487	3.52	Yes	Yes	2	9	9
90	R:R:N298	R:R:Y302	15.3349	3.49	Yes	Yes	2	9	9
91	R:R:D84	R:R:N298	15.2266	8.08	Yes	Yes	2	9	9
92	R:R:F129	R:R:Y76	17.8368	8.25	Yes	Yes	2	5	7
93	R:R:F129	R:R:V160	17.1412	6.55	Yes	Yes	2	5	7
94	R:R:V156	R:R:V160	17.1061	3.21	Yes	Yes	2	5	7
95	R:R:F87	R:R:Y116	15.8685	6.19	Yes	Yes	2	7	6
96	R:R:L125	R:R:V160	33.3118	4.47	No	Yes	0	5	7
97	R:R:L125	R:R:P211	33.0701	3.28	No	Yes	0	5	9
98	R:R:P211	R:R:V124	32.109	5.3	Yes	No	0	9	7
99	R:R:V124	R:R:W252	31.8706	3.68	No	Yes	0	7	9
100	R:R:W94	R:R:Y116	14.8668	5.79	No	Yes	2	7	6
101	R:R:H113	R:R:W94	14.4982	9.52	Yes	No	0	6	7
102	R:R:L120	R:R:Y121	15.364	4.69	Yes	Yes	2	7	7
103	R:R:W252	R:R:Y256	16.837	9.65	Yes	Yes	0	9	8
104	R:R:Q202	R:R:Y121	12.3123	3.38	No	Yes	2	3	7
105	R:R:F199	R:R:Q202	11.7001	3.51	Yes	No	2	5	3
106	R:R:I259	R:R:Q200	19.4137	5.49	No	No	0	5	5
107	R:R:I259	R:R:Y255	13.4786	10.88	No	Yes	0	5	7
108	R:R:D262	R:R:Q200	15.6937	6.53	No	No	0	5	5
109	R:R:D262	R:R:I284	14.1997	4.2	No	No	0	5	4
110	R:R:G258	R:R:I284	13.4527	3.53	No	No	0	4	4
111	R:R:G258	R:R:I261	12.7056	1.76	No	No	0	4	5
112	R:R:I261	R:R:V280	11.2114	6.14	No	No	0	5	5
113	A:A:F274	A:A:Y230	20.5297	5.16	Yes	Yes	3	9	8
114	A:A:R208	A:A:W211	78.8445	4	Yes	Yes	1	9	9
115	A:A:F215	A:A:W211	16.5737	4.01	Yes	Yes	1	9	9
116	A:A:F307	A:A:S246	20.0172	3.96	Yes	No	3	8	9
117	A:A:F223	A:A:F250	39.9377	13.93	No	Yes	0	9	9
118	B:B:L117	B:B:W99	13.2255	5.69	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L78	R:R:R70	6.07	0	No	Yes	5	6	1	2
R:R:L78	W:W:?1	13.9	0	No	Yes	5	0	1	0
R:R:H79	R:R:I126	3.98	2	Yes	Yes	9	7	1	2
R:R:H79	R:R:V156	9.69	2	Yes	Yes	9	5	1	2
R:R:H79	R:R:Y157	7.62	2	Yes	No	9	7	1	1
R:R:H79	R:R:W161	7.41	2	Yes	Yes	9	9	1	1
R:R:H79	W:W:?1	20.65	2	Yes	Yes	9	0	1	0
R:R:V82	W:W:?1	4.49	0	No	Yes	5	0	1	0
R:R:S122	R:R:W161	8.65	0	No	Yes	7	9	2	1
R:R:I126	R:R:V160	4.61	0	Yes	Yes	7	7	2	2
R:R:V156	R:R:Y157	6.31	2	Yes	No	5	7	2	1
R:R:V156	R:R:V160	3.21	2	Yes	Yes	5	7	2	2
R:R:Y157	W:W:?1	9.42	2	No	Yes	7	0	1	0
R:R:V160	R:R:W161	7.36	2	Yes	Yes	7	9	2	1
R:R:W161	W:W:?1	19.44	2	Yes	Yes	9	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
71.43	Single	8U4O	Cholesterol	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
62.50	Single	8U4Q	Cholesterol	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
57.14	Single	8U4P	Cholesterol	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
50.00	Single	8U4R	Cholesterol	8U4R-CXCR4-REGN7663-Fab-Cholesterol
37.50	Single	8T3O	2Y5	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	ffa4_on_allo	Other Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	adgrf1_on_allo	Other Ligand	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2 8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
22.22	Single	6KQI	ORG27569	6KQI-CB₁-PubMed 104895-ORG27569
22.22	Consensus	cb1_off_allo	Other Ligand	6KQI-CB₁-PubMed 104895-ORG27569
8.33	Single	5NDZ	AZ3451; Na	5NDZ-PAR2-AZ3451; Na
7.69	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
7.69	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/&β;1/&γ;2
7.14	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/&β;1/&γ;2
6.25	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2
5.88	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/&β;1/&γ;2

PDB Summary
PDB	8U4N
Class	A
SubFamily	Protein
Type	Chemokine
SubType	CXCR4
Species	Homo sapiens
Ligand	-
Other Ligand(s)	Cholesterol
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	2.72
Date	2024-03-13
D.O.I.	10.1101/2024.02.09.579708

Net Summary
I_min	2.93
Number of Linked Nodes	851
Number of Links	1100
Number of Hubs	204
Number of Links mediated by Hubs	721
Number of Communities	25
Number of Nodes involved in Communities	283
Number of Links involved in Communities	438

Path Summary
Number Of Nodes in MetaPath	119
Number Of Links MetaPath	118
Number of Shortest Paths	6528754
Length Of Smallest Path	3
Average Path Length	42.5563
Length of Longest Path	68
Minimum Path Strength	1.46
Average Path Strength	6.24166
Maximum Path Strength	23.7267
Minimum Path Correlation	0.7
Average Path Correlation	0.993666
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.72414
Average % Of Corr. Nodes	29.2764
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	54.9292
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	CLR
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	CLR
Name	Cholesterol
Synonyms	Cholest-5-en-3beta-ol Cholesterin (3β,14β,17α)-cholest-5-en-3-ol Cholesterol
Identifier	(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Formula	C27 H46 O
Molecular Weight	386.654
SMILES	CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
PubChem	5997
Formal Charge	0
Total Atoms	74
Total Chiral Atoms	8
Total Bonds	77
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8U4N_Chain_A S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K C T I V K Q M T G I V E T H F T F K D L H F K M F D V T A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E D E E M N R M H A S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8U4N_Chain_B Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8U4N_Chain_G A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P61073
Sequence	>8U4N_Chain_R F N K I F L P T I Y S I I F L T G I V G N G L V I L V M G Y Q K K L R S M T D K Y R L H L S V A D L L F V I T L P F W A V D A V A N W Y F G N F L C K A V H V I Y T V S L Y S S V L I L A F I S L D R Y L A I V H A T N S Q R P R K L L A E K V V Y V G V W I P A L L L T I P D F I F A N V S E A D D R Y I C D R F Y P N D L W V V V F Q F Q H I M V G L I L P G I V I L S C Y C I I I S K L S H S K G H Q K R K A L K T T V I L I L A F F A C W L P Y Y I G I S I D S F I L L E I I K Q G C E F E N T V H K W I S I T E A L A F F H C C L N P I L Y A F L G A K F K T S A Q H A L T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	3ODU	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	2.5	2010-10-27	10.1126/science.1194396
	3OE0	A	Protein	Chemokine	CXCR4	Homo sapiens	-	CVX15	-	2.9	2010-10-27	10.1126/science.1194396
	3OE6	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.2	2010-10-27	10.1126/science.1194396
	3OE8	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
	3OE9	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
	4RWS	A	Protein	Chemokine	CXCR4	Homo sapiens	vMIP-II	-	-	3.1	2015-02-11	10.1126/science.1261064
	8U4N	A	Protein	Chemokine	CXCR4	Homo sapiens	-	Cholesterol	Gi1/&β;1/&γ;2	2.72	2024-03-13	10.1101/2024.02.09.579708
	8U4O	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	Cholesterol	Gi1/&β;1/&γ;2	3.29	2024-03-13	10.1101/2024.02.09.579708
	8U4P	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	Cholesterol	Gi1/&β;1/&γ;2	3.15	2024-03-13	10.1101/2024.02.09.579708
	8U4Q	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	Cholesterol	Gi1/&β;1/&γ;2	3.36	2024-03-13	10.1101/2024.02.09.579708
	8U4R	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	Cholesterol	-	3.1	2024-03-13	10.1101/2024.02.09.579708
	3ODU (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	2.5	2010-10-27	10.1126/science.1194396
	3OE8 (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
	3OE9 (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8U4N.zip

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