psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:K22	L:L:P23	3.35	Yes	Yes	1	9	9
2	L:L:K22	L:L:L26	9.87	Yes	Yes	1	9	9
3	L:L:K22	R:R:W94	11.6	Yes	Yes	1	9	7
4	L:L:K22	R:R:H113	5.24	Yes	Yes	0	9	6
5	L:L:K22	R:R:D187	8.3	Yes	No	0	9	3
6	L:L:L26	L:L:P23	6.57	Yes	Yes	1	9	9
7	L:L:P23	R:R:W94	12.16	Yes	Yes	1	9	7
8	L:L:P23	R:R:Y116	11.13	Yes	Yes	1	9	6
9	L:L:P23	R:R:E288	6.29	Yes	Yes	1	9	5
10	L:L:P23	R:R:F292	5.78	Yes	Yes	1	9	7
11	L:L:V24	R:R:Y255	3.79	No	Yes	1	7	7
12	L:L:V24	R:R:I259	4.61	No	No	1	7	5
13	L:L:V24	R:R:E288	4.28	No	Yes	1	7	5
14	L:L:S25	R:R:S285	4.89	No	No	0	9	5
15	L:L:S25	R:R:E288	4.31	No	Yes	0	9	5
16	L:L:L26	R:R:W94	3.42	Yes	Yes	1	9	7
17	L:L:T52	L:L:Y28	8.74	Yes	No	4	8	8
18	L:L:P53	L:L:Y28	15.3	Yes	No	4	7	8
19	L:L:Q58	L:L:Y28	3.38	Yes	No	4	9	8
20	L:L:R29	R:R:R30	3.2	No	No	0	9	5
21	L:L:R29	R:R:D262	5.96	No	No	0	9	5
22	L:L:R29	R:R:L266	6.07	No	No	0	9	3
23	L:L:C30	L:L:C55	7.28	No	No	4	9	9
24	L:L:C30	L:L:Q58	4.58	No	Yes	4	9	9
25	L:L:P31	L:L:Q58	9.47	No	Yes	0	7	9
26	L:L:P31	R:R:F29	4.33	No	No	0	7	4
27	L:L:C32	L:L:C71	7.28	No	No	3	9	9
28	L:L:F34	L:L:R33	5.34	No	No	0	6	9
29	L:L:E36	L:L:F34	3.5	No	No	0	6	6
30	L:L:F34	R:R:E268	10.49	No	No	0	6	2
31	L:L:F35	L:L:P74	4.33	Yes	No	3	6	8
32	L:L:E36	L:L:V70	4.28	No	No	0	6	9
33	L:L:H38	L:L:V39	6.92	No	Yes	0	5	7
34	L:L:H38	L:L:N66	3.83	No	No	0	5	5
35	L:L:H38	L:L:V70	9.69	No	No	0	5	9
36	L:L:N43	L:L:V39	14.78	Yes	Yes	5	5	7
37	L:L:L63	L:L:V39	7.45	Yes	Yes	5	9	7
38	L:L:R41	L:L:W78	9	No	Yes	0	6	8
39	L:L:R41	L:L:Y82	11.32	No	No	0	6	8
40	L:L:L63	L:L:N43	8.24	Yes	Yes	5	9	5
41	L:L:K64	L:L:N43	4.2	No	Yes	0	8	5
42	L:L:N43	L:L:N65	17.71	Yes	No	0	5	4
43	L:L:L47	L:L:V44	4.47	No	No	5	9	7
44	L:L:A61	L:L:V44	3.39	No	No	5	9	7
45	L:L:K45	L:L:R62	6.19	No	Yes	0	7	6
46	L:L:K45	L:L:N67	4.2	No	No	0	7	6
47	L:L:H46	L:L:K48	20.96	No	Yes	6	8	7
48	L:L:H46	L:L:R62	3.39	No	Yes	6	8	6
49	L:L:A61	L:L:L47	6.3	No	No	5	9	9
50	L:L:K48	L:L:V60	6.07	Yes	Yes	6	7	8
51	L:L:K48	L:L:R62	8.66	Yes	Yes	6	7	6
52	L:L:K48	L:L:Q69	5.42	Yes	Yes	6	7	9
53	L:L:L50	L:L:Q58	11.98	No	Yes	0	5	9
54	L:L:L50	L:L:V60	8.94	No	Yes	0	5	8
55	L:L:P53	L:L:T52	3.5	Yes	Yes	4	7	8
56	L:L:C55	L:L:T52	8.45	No	Yes	4	9	8
57	L:L:Q58	L:L:T52	11.34	Yes	Yes	4	9	8
58	L:L:P53	R:R:S178	3.56	Yes	No	0	7	1
59	L:L:P53	R:R:I185	8.47	Yes	No	0	7	3
60	L:L:N54	R:R:F189	12.08	No	No	0	8	3
61	L:L:C55	L:L:Q58	6.1	No	Yes	4	9	9
62	L:L:Q69	L:L:V60	15.76	Yes	Yes	6	9	8
63	L:L:V60	R:R:P27	3.53	Yes	No	6	8	5
64	L:L:A61	L:L:I72	3.25	No	No	0	9	6
65	L:L:Q69	L:L:R62	7.01	Yes	Yes	6	9	6
66	L:L:L63	L:L:N66	9.61	Yes	No	0	9	5
67	L:L:L63	L:L:V70	5.96	Yes	No	0	9	9
68	L:L:N65	L:L:N66	16.35	No	No	0	4	5
69	L:L:N67	L:L:R68	10.85	No	No	0	6	8
70	L:L:R68	R:R:E26	3.49	No	No	0	8	2
71	L:L:Q69	R:R:P27	7.9	Yes	No	6	9	5
72	L:L:D73	L:L:P74	12.88	No	No	3	8	8
73	L:L:D73	L:L:K75	4.15	No	No	3	8	5
74	L:L:D73	L:L:L76	9.5	No	Yes	3	8	6
75	L:L:K75	L:L:P74	5.02	No	No	3	5	8
76	L:L:L76	L:L:W78	10.25	Yes	Yes	3	6	8
77	L:L:I79	L:L:L76	4.28	Yes	Yes	3	8	6
78	L:L:K77	L:L:W78	6.96	No	Yes	0	8	8
79	L:L:E81	L:L:K77	8.1	No	No	0	7	8
80	L:L:I79	L:L:W78	5.87	Yes	Yes	3	8	8
81	L:L:I79	L:L:Y82	3.63	Yes	No	0	8	8
82	L:L:L83	L:L:Y82	9.38	No	No	0	7	8
83	R:R:E26	R:R:K25	9.45	No	No	0	2	4
84	R:R:F29	R:R:P27	8.67	No	No	0	4	5
85	R:R:C274	R:R:C28	7.28	No	No	0	5	9
86	R:R:C28	R:R:E277	6.08	No	No	0	9	2
87	R:R:H281	R:R:R30	15.8	Yes	No	0	4	5
88	R:R:N278	R:R:N33	4.09	No	No	0	3	6
89	R:R:H281	R:R:N33	12.75	Yes	No	0	4	6
90	R:R:K282	R:R:N33	8.39	No	No	0	2	6
91	R:R:K38	R:R:N35	6.99	No	No	0	4	3
92	R:R:F36	R:R:F40	9.65	No	Yes	0	4	5
93	R:R:F36	R:R:K282	3.72	No	No	0	4	2
94	R:R:F36	R:R:I286	5.02	No	No	0	4	6
95	R:R:L41	R:R:N37	4.12	Yes	No	0	6	3
96	R:R:H281	R:R:N37	3.83	Yes	No	9	4	3
97	R:R:N37	R:R:S285	5.96	No	No	9	3	5
98	R:R:I39	R:R:K38	4.36	No	No	0	5	4
99	R:R:F40	R:R:L41	3.65	Yes	Yes	0	5	6
100	R:R:F40	R:R:I44	3.77	Yes	No	0	5	5
101	R:R:L41	R:R:Y45	7.03	Yes	No	0	6	7
102	R:R:F292	R:R:Y45	6.19	Yes	No	0	7	7
103	R:R:F293	R:R:I48	13.82	No	No	0	5	7
104	R:R:C296	R:R:I48	3.27	No	No	0	7	7
105	R:R:F49	R:R:P92	7.22	No	No	0	6	9
106	R:R:C296	R:R:T51	5.07	No	No	0	7	5
107	R:R:I53	R:R:L85	4.28	No	No	0	5	7
108	R:R:G55	R:R:V54	3.68	No	No	0	8	4
109	R:R:G55	R:R:P299	4.06	No	No	0	8	9
110	R:R:D84	R:R:N56	9.42	No	Yes	0	9	9
111	R:R:N56	R:R:P299	4.89	Yes	No	0	9	9
112	R:R:S81	R:R:V59	6.46	No	No	0	9	8
113	R:R:A303	R:R:V59	3.39	No	No	7	7	8
114	R:R:F309	R:R:V59	3.93	Yes	No	7	8	8
115	R:R:I60	R:R:S81	4.64	No	No	0	7	9
116	R:R:F309	R:R:V62	9.18	Yes	No	0	8	7
117	R:R:A313	R:R:V62	3.39	No	No	0	5	7
118	R:R:D74	R:R:M63	6.93	No	Yes	7	8	6
119	R:R:M63	R:R:R77	4.96	Yes	Yes	7	6	8
120	R:R:K68	R:R:Q66	5.42	No	No	0	6	4
121	R:R:Q66	R:R:S312	8.66	No	No	0	4	6
122	R:R:L78	R:R:R70	6.07	No	No	0	5	6
123	R:R:D74	R:R:S71	7.36	No	No	0	8	7
124	R:R:D133	R:R:M72	5.54	No	Yes	10	8	6
125	R:R:M72	R:R:R148	6.2	Yes	Yes	10	6	6
126	R:R:A152	R:R:M72	4.83	No	Yes	0	3	6
127	R:R:R77	R:R:T73	5.17	Yes	No	0	8	7
128	R:R:D74	R:R:R77	10.72	No	Yes	7	8	8
129	R:R:E153	R:R:K75	10.8	No	No	0	7	6
130	R:R:F129	R:R:Y76	5.16	Yes	Yes	0	5	7
131	R:R:I130	R:R:Y76	6.04	No	Yes	0	8	7
132	R:R:D133	R:R:Y76	13.79	No	Yes	0	8	7
133	R:R:A152	R:R:Y76	4	No	Yes	0	3	7
134	R:R:F309	R:R:R77	5.34	Yes	Yes	7	8	8
135	R:R:H79	R:R:V156	4.15	No	No	11	9	5
136	R:R:H79	R:R:Y157	4.36	No	No	11	9	7
137	R:R:H79	R:R:W161	7.41	No	No	0	9	9
138	R:R:I126	R:R:L80	4.28	No	No	0	7	9
139	R:R:L80	R:R:N298	8.24	No	No	0	9	9
140	R:R:L80	R:R:Y302	3.52	No	Yes	0	9	9
141	R:R:A83	R:R:S122	3.42	No	No	0	8	7
142	R:R:C295	R:R:D84	6.22	No	No	0	9	9
143	R:R:D84	R:R:N298	6.73	No	No	0	9	9
144	R:R:L86	R:R:N119	9.61	No	No	0	7	8
145	R:R:F87	R:R:Y116	6.19	Yes	Yes	1	7	6
146	R:R:F87	R:R:L120	3.65	Yes	No	1	7	7
147	R:R:F292	R:R:F87	6.43	Yes	Yes	1	7	7
148	R:R:F87	R:R:H294	4.53	Yes	No	0	7	9
149	R:R:C295	R:R:F87	4.19	No	Yes	0	9	7
150	R:R:C295	R:R:V88	3.42	No	No	0	9	6
151	R:R:T90	R:R:W94	6.06	No	Yes	0	6	7
152	R:R:F104	R:R:F93	10.72	Yes	No	0	7	6
153	R:R:V112	R:R:W94	4.9	No	Yes	0	5	7
154	R:R:W94	R:R:Y116	9.65	Yes	Yes	1	7	6
155	R:R:F104	R:R:V96	6.55	Yes	No	0	7	5
156	R:R:D97	R:R:W102	3.35	No	Yes	0	5	9
157	R:R:D97	R:R:R183	8.34	No	No	0	5	3
158	R:R:A100	R:R:Y103	4	No	No	0	5	3
159	R:R:N101	R:R:Y103	15.12	No	No	0	4	3
160	R:R:F104	R:R:W102	18.04	Yes	Yes	0	7	9
161	R:R:C109	R:R:W102	7.84	Yes	Yes	8	9	9
162	R:R:C186	R:R:W102	11.75	No	Yes	8	9	9
163	R:R:F104	R:R:L108	6.09	Yes	No	0	7	5
164	R:R:N106	R:R:N176	4.09	No	No	0	3	4
165	R:R:N106	R:R:V177	7.39	No	No	0	3	4
166	R:R:C109	R:R:H113	4.42	Yes	Yes	0	9	6
167	R:R:C109	R:R:V177	3.42	Yes	No	8	9	4
168	R:R:C109	R:R:C186	7.28	Yes	No	8	9	9
169	R:R:D171	R:R:H113	7.56	Yes	Yes	0	4	6
170	R:R:A175	R:R:H113	5.85	No	Yes	0	4	6
171	R:R:T168	R:R:V114	4.76	No	No	0	6	5
172	R:R:F172	R:R:V114	6.55	No	No	0	4	5
173	R:R:I115	R:R:N119	4.25	No	No	0	5	8
174	R:R:L120	R:R:Y116	3.52	No	Yes	1	7	6
175	R:R:F292	R:R:Y116	6.19	Yes	Yes	1	7	6
176	R:R:D171	R:R:T117	7.23	Yes	No	0	4	5
177	R:R:L167	R:R:Y121	5.86	No	Yes	1	5	7
178	R:R:Q202	R:R:Y121	4.51	No	Yes	1	3	7
179	R:R:H203	R:R:Y121	8.71	No	Yes	1	4	7
180	R:R:V206	R:R:Y121	6.31	No	Yes	0	4	7
181	R:R:S122	R:R:W161	9.88	No	No	0	7	9
182	R:R:S123	R:R:V124	3.23	No	No	0	9	7
183	R:R:H294	R:R:S123	5.58	No	No	0	9	9
184	R:R:P211	R:R:V124	3.53	No	No	0	9	7
185	R:R:V124	R:R:W252	3.68	No	Yes	0	7	9
186	R:R:L125	R:R:V160	4.47	No	Yes	0	5	7
187	R:R:I126	R:R:V160	4.61	No	Yes	0	7	7
188	R:R:L127	R:R:Y302	8.21	No	Yes	0	8	9
189	R:R:A128	R:R:I215	3.25	No	No	0	7	7
190	R:R:F129	R:R:V160	3.93	Yes	Yes	0	5	7
191	R:R:I130	R:R:R134	5.01	No	No	2	8	9
192	R:R:I130	R:R:Y302	4.84	No	Yes	2	8	9
193	R:R:I215	R:R:S131	9.29	No	No	2	7	9
194	R:R:C218	R:R:S131	6.89	No	No	0	6	9
195	R:R:S131	R:R:Y219	12.72	No	Yes	2	9	8
196	R:R:D133	R:R:R148	15.48	No	Yes	10	8	6
197	R:R:L244	R:R:R134	3.64	Yes	No	2	7	9
198	R:R:R134	R:R:Y302	5.14	No	Yes	2	9	9
199	R:R:V139	R:R:Y135	11.36	No	Yes	12	7	8
200	R:R:H140	R:R:Y135	5.44	No	Yes	12	6	8
201	R:R:C218	R:R:Y135	5.38	No	Yes	0	6	8
202	R:R:I221	R:R:Y135	9.67	No	Yes	0	4	8
203	R:R:L136	R:R:R148	3.64	No	Yes	0	5	6
204	R:R:A137	R:R:R148	6.91	No	Yes	0	8	6
205	R:R:I138	R:R:I222	5.89	No	No	0	8	8
206	R:R:H140	R:R:V139	4.15	No	No	12	6	7
207	R:R:K225	R:R:V139	6.07	No	No	0	4	7
208	R:R:H140	R:R:N143	5.1	No	No	0	6	5
209	R:R:N143	R:R:T142	5.85	No	No	0	5	5
210	R:R:R148	R:R:S144	5.27	Yes	No	0	6	5
211	R:R:E153	R:R:K149	4.05	No	No	0	7	6
212	R:R:L150	R:R:V155	4.47	No	No	0	4	2
213	R:R:L151	R:R:V155	4.47	No	No	0	4	2
214	R:R:V156	R:R:Y157	3.79	No	No	11	5	7
215	R:R:V156	R:R:V160	3.21	No	Yes	0	5	7
216	R:R:G159	R:R:P163	4.06	No	No	0	3	4
217	R:R:V160	R:R:W161	7.36	Yes	No	0	7	9
218	R:R:I162	R:R:P163	5.08	No	No	0	4	4
219	R:R:L167	R:R:Q202	7.99	No	No	1	5	3
220	R:R:D171	R:R:T168	5.78	Yes	No	0	4	6
221	R:R:I169	R:R:P170	3.39	No	No	0	3	8
222	R:R:P170	R:R:R188	7.21	No	No	0	8	5
223	R:R:F199	R:R:P170	8.67	Yes	No	0	5	8
224	R:R:D171	R:R:R188	10.72	Yes	No	0	4	5
225	R:R:F174	R:R:I173	12.56	No	No	0	4	3
226	R:R:F174	R:R:Y190	8.25	No	Yes	1	4	4
227	R:R:F174	R:R:W195	5.01	No	Yes	1	4	5
228	R:R:C186	R:R:V177	3.42	No	No	8	9	4
229	R:R:F189	R:R:S178	9.25	No	No	0	3	1
230	R:R:D181	R:R:D182	10.65	No	No	0	2	6
231	R:R:I185	R:R:R183	3.76	No	No	0	3	3
232	R:R:D187	R:R:F189	4.78	No	No	0	3	3
233	R:R:R188	R:R:Y190	13.38	No	Yes	0	5	4
234	R:R:P191	R:R:Y190	4.17	No	Yes	1	5	4
235	R:R:W195	R:R:Y190	3.86	Yes	Yes	1	5	4
236	R:R:V196	R:R:Y190	6.31	No	Yes	0	4	4
237	R:R:F199	R:R:Y190	12.38	Yes	Yes	1	5	4
238	R:R:N192	R:R:P191	8.15	Yes	No	1	1	5
239	R:R:P191	R:R:W195	14.86	No	Yes	1	5	5
240	R:R:N192	R:R:W195	7.91	Yes	Yes	1	1	5
241	R:R:F199	R:R:W195	5.01	Yes	Yes	1	5	5
242	R:R:S263	R:R:V197	4.85	No	No	0	5	3
243	R:R:L266	R:R:V197	4.47	No	No	0	3	3
244	R:R:L267	R:R:V197	11.92	No	No	0	1	3
245	R:R:F199	R:R:Q202	5.86	Yes	No	1	5	3
246	R:R:D262	R:R:Q200	5.22	No	No	0	5	5
247	R:R:Q200	R:R:S263	5.78	No	No	0	5	5
248	R:R:F201	R:R:S263	9.25	No	No	0	4	5
249	R:R:H203	R:R:Y255	4.36	No	Yes	1	4	7
250	R:R:H203	R:R:Y256	10.89	No	Yes	1	4	8
251	R:R:I209	R:R:M205	4.37	No	No	0	4	4
252	R:R:L210	R:R:M205	4.24	No	No	0	6	4
253	R:R:G207	R:R:Y256	4.35	No	Yes	0	5	8
254	R:R:L208	R:R:Y256	9.38	No	Yes	0	8	8
255	R:R:I215	R:R:Y219	6.04	No	Yes	2	7	8
256	R:R:I245	R:R:L216	4.28	No	No	0	7	4
257	R:R:F249	R:R:L216	8.53	No	No	0	4	4
258	R:R:T241	R:R:Y219	4.99	No	Yes	0	7	8
259	R:R:L244	R:R:Y219	7.03	Yes	Yes	2	7	8
260	R:R:I245	R:R:Y219	8.46	No	Yes	0	7	8
261	R:R:I223	R:R:L238	5.71	No	No	0	4	5
262	R:R:I223	R:R:T241	6.08	No	No	0	4	7
263	R:R:K234	R:R:L226	4.23	No	No	0	7	8
264	R:R:H228	R:R:S227	12.55	No	No	0	5	4
265	R:R:K234	R:R:S229	12.24	No	No	0	7	5
266	R:R:L244	R:R:L301	4.15	Yes	Yes	2	7	7
267	R:R:L244	R:R:Y302	7.03	Yes	Yes	2	7	9
268	R:R:F248	R:R:F249	9.65	No	No	13	9	4
269	R:R:F248	R:R:W252	7.02	No	Yes	0	9	9
270	R:R:W252	R:R:Y256	8.68	Yes	Yes	0	9	8
271	R:R:H294	R:R:W252	12.7	No	Yes	0	9	9
272	R:R:P254	R:R:T287	5.25	No	No	0	9	6
273	R:R:Y255	R:R:Y256	8.94	Yes	Yes	1	7	8
274	R:R:I259	R:R:Y255	9.67	No	Yes	1	5	7
275	R:R:T287	R:R:Y255	3.75	No	Yes	0	6	7
276	R:R:E288	R:R:Y255	16.83	Yes	Yes	1	5	7
277	R:R:D262	R:R:I284	4.2	No	No	0	5	4
278	R:R:I265	R:R:I270	4.42	No	No	0	3	5
279	R:R:F276	R:R:I265	3.77	No	No	0	1	3
280	R:R:F276	R:R:Q272	7.03	No	No	0	1	2
281	R:R:C274	R:R:N278	4.72	No	No	0	5	3
282	R:R:F276	R:R:V280	5.24	No	No	0	1	5
283	R:R:H281	R:R:S285	6.97	Yes	No	9	4	5
284	R:R:T287	R:R:W283	12.13	No	No	0	6	6
285	R:R:E288	R:R:F292	12.83	Yes	Yes	1	5	7
286	R:R:L297	R:R:L301	4.15	No	Yes	2	6	7
287	R:R:A303	R:R:F309	8.32	No	Yes	7	7	8
288	R:R:F304	R:R:F309	6.43	No	Yes	0	6	8
289	R:R:C220	R:R:L216	3.17	No	No	0	3	4
290	L:L:A42	L:L:N43	3.13	No	Yes	0	5	5
291	R:R:I261	R:R:V280	3.07	No	No	0	5	5
292	R:R:I284	R:R:V280	3.07	No	No	0	4	5
293	R:R:K67	R:R:S319	3.06	No	No	0	6	3
294	R:R:K38	R:R:V99	3.04	No	No	0	4	4
295	R:R:I115	R:R:T90	3.04	No	No	0	5	6
296	R:R:F129	R:R:G159	3.01	Yes	No	0	5	3
297	L:L:L76	L:L:S37	3	Yes	No	0	6	6
298	R:R:G231	R:R:R235	3	No	No	0	4	5
299	R:R:N56	R:R:S81	2.98	Yes	No	0	9	9
300	R:R:L86	R:R:V82	2.98	No	No	0	7	5
301	R:R:L91	R:R:V88	2.98	No	No	0	8	6
302	R:R:L165	R:R:V118	2.98	No	No	0	3	5
303	R:R:L246	R:R:V242	2.98	No	No	0	5	4
304	R:R:N119	R:R:V118	2.96	No	No	0	8	5
305	L:L:S27	R:R:D187	2.94	No	No	0	6	3
306	L:L:I49	L:L:I59	2.94	No	No	0	9	9
307	L:L:I59	L:L:I72	2.94	No	No	0	9	6
308	R:R:I44	R:R:I48	2.94	No	No	0	5	7
309	R:R:I204	R:R:I259	2.94	No	No	0	5	5
310	R:R:K149	R:R:M72	2.88	No	Yes	0	6	6
311	L:L:K45	L:L:K64	2.87	No	No	0	7	8
312	R:R:I222	R:R:L226	2.85	No	No	0	8	8
313	R:R:L78	R:R:M63	2.83	No	Yes	0	5	6
314	R:R:K154	R:R:L150	2.82	No	No	0	3	4
315	R:R:G258	R:R:W283	2.81	No	No	0	4	6
316	L:L:C32	L:L:F35	2.79	No	Yes	3	9	6
317	L:L:C71	L:L:F35	2.79	No	Yes	3	9	6
318	R:R:A289	R:R:F40	2.77	No	Yes	0	4	5
319	R:R:L132	R:R:L151	2.77	No	No	0	6	4
320	R:R:L208	R:R:L253	2.77	No	No	0	8	5
321	R:R:L85	R:R:N56	2.75	No	Yes	0	7	9
322	L:L:I79	L:L:Q80	2.74	Yes	No	0	8	8
323	R:R:E32	R:R:K282	2.7	No	No	0	4	2
324	R:R:A95	R:R:Y45	2.67	No	No	0	7	7
325	R:R:R235	R:R:S229	2.64	No	No	0	5	5
326	R:R:F49	R:R:V88	2.62	No	No	0	6	6
327	R:R:H232	R:R:K236	2.62	No	No	0	4	8
328	R:R:A291	R:R:W252	2.59	No	Yes	0	8	9
329	R:R:V320	R:R:Y65	2.52	No	No	0	4	5
330	L:L:F35	L:L:I59	2.51	Yes	No	0	6	9
331	R:R:F264	R:R:I270	2.51	No	No	0	4	5
332	R:R:F107	R:R:L108	2.44	No	No	0	1	5
333	R:R:F129	R:R:L151	2.44	Yes	No	0	5	4
334	R:R:L238	R:R:R235	2.43	No	No	0	5	5
335	R:R:N101	R:R:R183	2.41	No	No	0	4	3
336	R:R:N101	R:R:Y184	2.33	No	No	0	4	5
337	R:R:C296	R:R:G52	1.96	No	No	0	7	8
338	R:R:G159	R:R:V158	1.84	No	No	0	3	4
339	R:R:P147	R:R:S144	1.78	No	No	0	4	5
340	R:R:G258	R:R:I257	1.76	No	No	0	4	6
341	R:R:G64	R:R:M63	1.75	No	Yes	0	2	6
342	R:R:G231	R:R:K230	1.74	No	No	0	4	5
343	R:R:G55	R:R:L58	1.71	No	No	0	8	5
344	R:R:A164	R:R:S122	1.71	No	No	0	7	7
345	R:R:C218	R:R:V214	1.71	No	No	0	6	6
346	R:R:L41	R:R:P42	1.64	Yes	No	0	6	5
347	R:R:L210	R:R:P211	1.64	No	No	0	6	9
348	R:R:G273	R:R:Q272	1.64	No	No	0	5	2
349	R:R:S312	R:R:V62	1.62	No	No	0	6	7
350	R:R:A180	R:R:I185	1.62	No	No	0	1	3
351	L:L:V39	L:L:V44	1.6	Yes	No	5	7	7
352	R:R:G231	R:R:H232	1.59	No	No	0	4	4
353	R:R:C251	R:R:L297	1.59	No	No	0	8	6
354	L:L:L26	R:R:A98	1.58	Yes	No	0	9	5
355	R:R:A98	R:R:L41	1.58	No	Yes	0	5	6
356	R:R:A237	R:R:L226	1.58	No	No	0	7	8
357	R:R:A247	R:R:L297	1.58	No	No	2	6	6
358	R:R:A247	R:R:L301	1.58	No	Yes	2	6	7
359	R:R:I204	R:R:S260	1.55	No	No	0	5	5
360	R:R:I213	R:R:S217	1.55	No	No	0	3	3
361	R:R:I221	R:R:S224	1.55	No	No	0	4	4
362	R:R:I261	R:R:S260	1.55	No	No	0	5	5
363	R:R:I223	R:R:V242	1.54	No	No	0	4	4
364	R:R:I47	R:R:T43	1.52	No	No	0	4	4
365	R:R:I47	R:R:T51	1.52	No	No	0	4	5
366	R:R:I89	R:R:T90	1.52	No	No	0	4	6
367	R:R:F248	R:R:G212	1.51	No	No	13	9	6
368	R:R:F249	R:R:G212	1.51	No	No	13	4	6
369	R:R:K239	R:R:T240	1.5	No	No	0	6	7
370	R:R:L317	R:R:V320	1.49	No	No	0	5	4
371	R:R:I209	R:R:I213	1.47	No	No	0	4	3
372	R:R:I269	R:R:I270	1.47	No	No	0	1	5
373	R:R:I243	R:R:K239	1.45	No	No	0	5	6
374	R:R:P147	R:R:R146	1.44	No	No	0	4	5
375	R:R:I162	R:R:L166	1.43	No	No	0	4	4
376	R:R:I243	R:R:L301	1.43	No	Yes	0	5	7
377	L:L:I49	L:L:N51	1.42	No	No	0	9	7
378	R:R:G105	R:R:W102	1.41	No	Yes	0	8	9
379	R:R:E275	R:R:T279	1.41	No	No	0	3	2
380	R:R:K110	R:R:N176	1.4	No	No	0	7	4
381	R:R:L194	R:R:N192	1.37	No	Yes	0	2	1
382	R:R:D193	R:R:N192	1.35	No	Yes	0	1	1
383	R:R:F304	R:R:I300	1.26	No	No	0	6	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:K22	7.672	5	1	9
2	L:L:P23	7.54667	6	1	9
3	L:L:L26	5.36	4	1	9
4	L:L:F35	3.105	4	3	6
5	L:L:V39	7.6875	4	5	7
6	L:L:N43	9.612	5	5	5
7	L:L:K48	10.2775	4	6	7
8	L:L:T52	8.0075	4	4	8
9	L:L:P53	7.7075	4	4	7
10	L:L:Q58	7.80833	6	4	9
11	L:L:V60	8.575	4	6	8
12	L:L:R62	6.3125	4	6	6
13	L:L:L63	7.815	4	5	9
14	L:L:Q69	9.0225	4	6	9
15	L:L:L76	6.7575	4	3	6
16	L:L:W78	8.02	4	3	8
17	L:L:I79	4.13	4	3	8
18	R:R:F40	4.96	4	0	5
19	R:R:L41	3.604	5	0	6
20	R:R:N56	5.01	4	0	9
21	R:R:M63	4.1175	4	7	6
22	R:R:M72	4.8625	4	10	6
23	R:R:Y76	7.2475	4	0	7
24	R:R:R77	6.5475	4	7	8
25	R:R:F87	4.998	5	1	7
26	R:R:W94	7.965	6	1	7
27	R:R:W102	8.478	5	8	9
28	R:R:F104	10.35	4	0	7
29	R:R:C109	5.74	4	8	9
30	R:R:H113	5.7675	4	0	6
31	R:R:Y116	7.336	5	1	6
32	R:R:Y121	6.3475	4	1	7
33	R:R:F129	3.635	4	0	5
34	R:R:Y135	7.9625	4	12	8
35	R:R:R148	7.5	5	10	6
36	R:R:V160	4.716	5	0	7
37	R:R:D171	7.8225	4	0	4
38	R:R:Y190	8.05833	6	1	4
39	R:R:N192	4.695	4	1	1
40	R:R:W195	7.33	5	1	5
41	R:R:F199	7.98	4	1	5
42	R:R:Y219	7.848	5	2	8
43	R:R:L244	5.4625	4	2	7
44	R:R:W252	6.934	5	0	9
45	R:R:Y255	7.89	6	1	7
46	R:R:Y256	8.448	5	1	8
47	R:R:H281	9.8375	4	9	4
48	R:R:E288	8.908	5	1	5
49	R:R:F292	7.484	5	1	7
50	R:R:L301	2.8275	4	2	7
51	R:R:Y302	5.748	5	2	9
52	R:R:F309	6.64	5	7	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:K22	L:L:P23	75.1763	3.35	Yes	Yes	1	9	9
2	L:L:P23	R:R:Y116	29.1129	11.13	Yes	Yes	1	9	6
3	L:L:K22	R:R:W94	30.3978	11.6	Yes	Yes	1	9	7
4	R:R:W94	R:R:Y116	30.1252	9.65	Yes	Yes	1	7	6
5	L:L:P23	R:R:E288	18.198	6.29	Yes	Yes	1	9	5
6	L:L:P23	R:R:F292	29.2374	5.78	Yes	Yes	1	9	7
7	R:R:E288	R:R:Y255	15.2096	16.83	Yes	Yes	1	5	7
8	L:L:K22	R:R:D187	100	8.3	Yes	No	0	9	3
9	R:R:D187	R:R:F189	99.297	4.78	No	No	0	3	3
10	R:R:F189	R:R:S178	98.5913	9.25	No	No	0	3	1
11	L:L:P53	R:R:S178	98.2467	3.56	Yes	No	0	7	1
12	L:L:P53	L:L:T52	50.6847	3.5	Yes	Yes	4	7	8
13	L:L:P53	L:L:Y28	49.6662	15.3	Yes	No	4	7	8
14	L:L:Q58	L:L:Y28	49.2233	3.38	Yes	No	4	9	8
15	L:L:Q58	L:L:T52	49.2282	11.34	Yes	Yes	4	9	8
16	L:L:F35	L:L:I59	33.0222	2.51	Yes	No	0	6	9
17	L:L:I59	L:L:I72	39.1851	2.94	No	No	0	9	6
18	L:L:A61	L:L:I72	41.2373	3.25	No	No	0	9	6
19	L:L:A61	L:L:V44	43.2736	3.39	No	No	5	9	7
20	L:L:V39	L:L:V44	47.3842	1.6	Yes	No	5	7	7
21	L:L:N43	L:L:V39	51.2492	14.78	Yes	Yes	5	5	7
22	L:L:K64	L:L:N43	73.6388	4.2	No	Yes	0	8	5
23	L:L:K45	L:L:K64	75.6634	2.87	No	No	0	7	8
24	L:L:K45	L:L:R62	85.7653	6.19	No	Yes	0	7	6
25	L:L:K48	L:L:R62	43.8326	8.66	Yes	Yes	6	7	6
26	L:L:K48	L:L:V60	45.8496	6.07	Yes	Yes	6	7	8
27	L:L:L50	L:L:V60	92.5993	8.94	No	Yes	0	5	8
28	L:L:L50	L:L:Q58	93.5583	11.98	No	Yes	0	5	9
29	L:L:Q69	L:L:R62	43.9212	7.01	Yes	Yes	6	9	6
30	L:L:Q69	L:L:V60	44.8221	15.76	Yes	Yes	6	9	8
31	L:L:L63	L:L:V70	10.2438	5.96	Yes	No	0	9	9
32	L:L:L63	L:L:N43	14.2534	8.24	Yes	Yes	5	9	5
33	L:L:F35	L:L:P74	26.9029	4.33	Yes	No	3	6	8
34	L:L:D73	L:L:P74	22.7715	12.88	No	No	3	8	8
35	L:L:D73	L:L:L76	20.7152	9.5	No	Yes	3	8	6
36	R:R:F87	R:R:Y116	58.5406	6.19	Yes	Yes	1	7	6
37	R:R:C295	R:R:F87	68.2184	4.19	No	Yes	0	9	7
38	R:R:F292	R:R:F87	35.976	6.43	Yes	Yes	1	7	7
39	R:R:C295	R:R:D84	65.4715	6.22	No	No	0	9	9
40	R:R:D84	R:R:N56	18.5896	9.42	No	Yes	0	9	9
41	R:R:N56	R:R:S81	13.8576	2.98	Yes	No	0	9	9
42	R:R:S81	R:R:V59	12.4911	6.46	No	No	0	9	8
43	R:R:F309	R:R:V59	11.1087	3.93	Yes	No	7	8	8
44	R:R:D84	R:R:N298	49.5375	6.73	No	No	0	9	9
45	R:R:L80	R:R:N298	48.9493	8.24	No	No	0	9	9
46	R:R:L80	R:R:Y302	34.4773	3.52	No	Yes	0	9	9
47	R:R:I130	R:R:Y302	12.8191	4.84	No	Yes	2	8	9
48	R:R:I130	R:R:Y76	13.3345	6.04	No	Yes	0	8	7
49	R:R:I126	R:R:L80	14.598	4.28	No	No	0	7	9
50	R:R:I126	R:R:V160	13.9434	4.61	No	Yes	0	7	7
51	R:R:F87	R:R:H294	29.5723	4.53	Yes	No	0	7	9
52	L:L:K22	R:R:H113	18.9819	5.24	Yes	Yes	0	9	6
53	R:R:H294	R:R:W252	24.5387	12.7	No	Yes	0	9	9
54	R:R:W252	R:R:Y256	11.1066	8.68	Yes	Yes	0	9	8
55	R:R:F248	R:R:W252	27.4848	7.02	No	Yes	0	9	9
56	R:R:F248	R:R:F249	26.0394	9.65	No	No	13	9	4
57	R:R:F249	R:R:L216	25.4388	8.53	No	No	0	4	4
58	R:R:I245	R:R:L216	24.1609	4.28	No	No	0	7	4
59	R:R:I245	R:R:Y219	23.5195	8.46	No	Yes	0	7	8
60	R:R:L244	R:R:Y302	22.2353	7.03	Yes	Yes	2	7	9
61	R:R:L244	R:R:Y219	19.0822	7.03	Yes	Yes	2	7	8
62	R:R:S131	R:R:Y219	14.7723	12.72	No	Yes	2	9	8
63	R:R:C218	R:R:S131	13.4501	6.89	No	No	0	6	9
64	R:R:C218	R:R:Y135	10.771	5.38	No	Yes	0	6	8
65	R:R:T241	R:R:Y219	21.4541	4.99	No	Yes	0	7	8
66	R:R:I223	R:R:T241	20.1236	6.08	No	No	0	4	7
67	R:R:I223	R:R:L238	16.1236	5.71	No	No	0	4	5
68	R:R:L238	R:R:R235	14.7875	2.43	No	No	0	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:K22	R:R:W94	11.6	1	Yes	Yes	9	7	0	1
L:L:K22	R:R:H113	5.24	1	Yes	Yes	9	6	0	1
L:L:K22	R:R:D187	8.3	1	Yes	No	9	3	0	1
L:L:P23	R:R:W94	12.16	1	Yes	Yes	9	7	0	1
L:L:P23	R:R:Y116	11.13	1	Yes	Yes	9	6	0	1
L:L:P23	R:R:E288	6.29	1	Yes	Yes	9	5	0	1
L:L:P23	R:R:F292	5.78	1	Yes	Yes	9	7	0	1
L:L:V24	R:R:Y255	3.79	1	No	Yes	7	7	0	1
L:L:V24	R:R:I259	4.61	1	No	No	7	5	0	1
L:L:V24	R:R:E288	4.28	1	No	Yes	7	5	0	1
L:L:S25	R:R:S285	4.89	0	No	No	9	5	0	1
L:L:S25	R:R:E288	4.31	0	No	Yes	9	5	0	1
L:L:L26	R:R:W94	3.42	1	Yes	Yes	9	7	0	1
L:L:R29	R:R:R30	3.2	0	No	No	9	5	0	1
L:L:R29	R:R:D262	5.96	0	No	No	9	5	0	1
L:L:R29	R:R:L266	6.07	0	No	No	9	3	0	1
L:L:P31	R:R:F29	4.33	0	No	No	7	4	0	1
L:L:F34	R:R:E268	10.49	0	No	No	6	2	0	1
L:L:P53	R:R:S178	3.56	4	Yes	No	7	1	0	1
L:L:P53	R:R:I185	8.47	4	Yes	No	7	3	0	1
L:L:N54	R:R:F189	12.08	0	No	No	8	3	0	1
L:L:V60	R:R:P27	3.53	6	Yes	No	8	5	0	1
L:L:R68	R:R:E26	3.49	0	No	No	8	2	0	1
L:L:Q69	R:R:P27	7.9	6	Yes	No	9	5	0	1
R:R:E26	R:R:K25	9.45	0	No	No	2	4	1	2
R:R:F29	R:R:P27	8.67	0	No	No	4	5	1	1
R:R:H281	R:R:R30	15.8	9	Yes	No	4	5	2	1
R:R:L41	R:R:N37	4.12	0	Yes	No	6	3	2	2
R:R:H281	R:R:N37	3.83	9	Yes	No	4	3	2	2
R:R:N37	R:R:S285	5.96	9	No	No	3	5	2	1
R:R:L41	R:R:Y45	7.03	0	Yes	No	6	7	2	2
R:R:F292	R:R:Y45	6.19	1	Yes	No	7	7	1	2
R:R:F87	R:R:Y116	6.19	1	Yes	Yes	7	6	2	1
R:R:F87	R:R:L120	3.65	1	Yes	No	7	7	2	2
R:R:F292	R:R:F87	6.43	1	Yes	Yes	7	7	1	2
R:R:T90	R:R:W94	6.06	0	No	Yes	6	7	2	1
R:R:V112	R:R:W94	4.9	0	No	Yes	5	7	2	1
R:R:W94	R:R:Y116	9.65	1	Yes	Yes	7	6	1	1
R:R:C109	R:R:H113	4.42	8	Yes	Yes	9	6	2	1
R:R:D171	R:R:H113	7.56	0	Yes	Yes	4	6	2	1
R:R:A175	R:R:H113	5.85	0	No	Yes	4	6	2	1
R:R:L120	R:R:Y116	3.52	1	No	Yes	7	6	2	1
R:R:F292	R:R:Y116	6.19	1	Yes	Yes	7	6	1	1
R:R:F189	R:R:S178	9.25	0	No	No	3	1	1	1
R:R:I185	R:R:R183	3.76	0	No	No	3	3	1	2
R:R:D187	R:R:F189	4.78	0	No	No	3	3	1	1
R:R:L266	R:R:V197	4.47	0	No	No	3	3	1	2
R:R:D262	R:R:Q200	5.22	0	No	No	5	5	1	2
R:R:H203	R:R:Y255	4.36	1	No	Yes	4	7	2	1
R:R:H203	R:R:Y256	10.89	1	No	Yes	4	8	2	2
R:R:Y255	R:R:Y256	8.94	1	Yes	Yes	7	8	1	2
R:R:I259	R:R:Y255	9.67	1	No	Yes	5	7	1	1
R:R:T287	R:R:Y255	3.75	0	No	Yes	6	7	2	1
R:R:E288	R:R:Y255	16.83	1	Yes	Yes	5	7	1	1
R:R:D262	R:R:I284	4.2	0	No	No	5	4	1	2
R:R:H281	R:R:S285	6.97	9	Yes	No	4	5	2	1
R:R:E288	R:R:F292	12.83	1	Yes	Yes	5	7	1	1
L:L:S27	R:R:D187	2.94	0	No	No	6	3	0	1
R:R:I204	R:R:I259	2.94	0	No	No	5	5	2	1
R:R:A180	R:R:I185	1.62	0	No	No	1	3	2	1
L:L:L26	R:R:A98	1.58	1	Yes	No	9	5	0	1
R:R:A98	R:R:L41	1.58	0	No	Yes	5	6	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8K3Z_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.2
Number of Linked Nodes	329
Number of Links	383
Number of Hubs	52
Number of Links mediated by Hubs	186
Number of Communities	13
Number of Nodes involved in Communities	85
Number of Links involved in Communities	114

Path Summary
Number Of Nodes in MetaPath	69
Number Of Links MetaPath	68
Number of Shortest Paths	212314
Length Of Smallest Path	3
Average Path Length	23.1747
Length of Longest Path	45
Minimum Path Strength	1.36
Average Path Strength	6.66711
Maximum Path Strength	17.03
Minimum Path Correlation	0.71
Average Path Correlation	0.946268
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.63158
Average % Of Corr. Nodes	41.9738
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.26
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • multicellular organismal process • system process • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating G protein-coupled receptor signaling pathway • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • sperm principal piece • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • molecular function activator activity • signaling receptor regulator activity • growth factor activity • receptor ligand activity • signaling receptor activator activity • cytokine receptor binding • chemokine receptor binding • chemokine activity • cytokine activity • CXCR chemokine receptor binding • cell adhesion molecule binding • integrin binding • cellular component biogenesis • cellular component assembly • protein-containing complex organization • protein-containing complex assembly • integrin activation • response to mechanical stimulus • response to abiotic stimulus • response to external stimulus • response to ultrasound • chemokine (C-X-C motif) ligand 12 signaling pathway • developmental process • head development • forebrain development • animal organ development • brain development • nervous system development • multicellular organism development • telencephalon cell migration • central nervous system development • forebrain cell migration • anatomical structure development • telencephalon development • system development • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • calcium ion homeostasis • cellular homeostasis • chemical homeostasis • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • defense response • response to stress • regulation of actin filament-based process • regulation of cellular component size • actin filament-based process • actin polymerization or depolymerization • regulation of actin filament organization • actin cytoskeleton organization • regulation of actin polymerization or depolymerization • actin filament organization • regulation of actin filament length • regulation of actin cytoskeleton organization • regulation of supramolecular fiber organization • supramolecular fiber organization • regulation of anatomical structure size • chemotaxis • taxis • locomotion • detection of external stimulus • nervous system process • sensory perception of temperature stimulus • sensory perception of pain • detection of temperature stimulus involved in sensory perception • response to temperature stimulus • detection of abiotic stimulus • detection of stimulus • sensory perception • detection of temperature stimulus • detection of stimulus involved in sensory perception • detection of temperature stimulus involved in sensory perception of pain • cell chemotaxis • positive regulation of monocyte chemotaxis • positive regulation of locomotion • regulation of cell motility • regulation of response to external stimulus • positive regulation of chemotaxis • positive regulation of cell migration • regulation of monocyte chemotaxis • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of cell motility • regulation of cell migration • myeloid leukocyte migration • positive regulation of mononuclear cell migration • regulation of immune system process • regulation of mononuclear cell migration • positive regulation of immune system process • regulation of leukocyte chemotaxis • regulation of leukocyte migration • positive regulation of leukocyte migration • positive regulation of leukocyte chemotaxis • regulation of chemotaxis • monocyte chemotaxis • regulation of response to stimulus • regulation of locomotion • leukocyte chemotaxis • regulation of calcium ion import • regulation of calcium ion transport • positive regulation of calcium ion transport • positive regulation of calcium ion import • regulation of monoatomic ion transport • calcium ion transport • metal ion transport • positive regulation of transport • positive regulation of monoatomic ion transport • monoatomic ion transport • calcium ion import • monoatomic cation transport • regulation of metal ion transport • regulation of lymphocyte migration • positive regulation of lymphocyte migration • positive regulation of T cell migration • regulation of T cell migration • cell adhesion • response to decreased oxygen levels • response to hypoxia • response to oxygen levels • negative regulation of intracellular signal transduction • regulation of cellular response to stress • regulation of signal transduction • regulation of intrinsic apoptotic signaling pathway in response to DNA damage • regulation of programmed cell death • regulation of intrinsic apoptotic signaling pathway • intracellular signal transduction • cellular response to stress • regulation of intracellular signal transduction • negative regulation of apoptotic signaling pathway • regulation of response to stress • intrinsic apoptotic signaling pathway in response to DNA damage • intrinsic apoptotic signaling pathway • negative regulation of response to stimulus • negative regulation of programmed cell death • regulation of apoptotic process • cell death • negative regulation of signal transduction • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage • apoptotic signaling pathway • negative regulation of intrinsic apoptotic signaling pathway • negative regulation of apoptotic process • DNA damage response • apoptotic process • programmed cell death • regulation of apoptotic signaling pathway • adult locomotory behavior • behavior • adult behavior • locomotory behavior • detection of mechanical stimulus involved in sensory perception of pain • detection of mechanical stimulus involved in sensory perception • sensory perception of mechanical stimulus • detection of mechanical stimulus • positive chemotaxis • positive regulation of positive chemotaxis • induction of positive chemotaxis • regulation of positive chemotaxis • immune response • axon extension • positive regulation of nervous system development • regulation of growth • axonogenesis • developmental growth • cell projection organization • regulation of cell differentiation • regulation of neurogenesis • neuron projection development • regulation of cell development • positive regulation of axon extension involved in axon guidance • positive regulation of developmental process • cell projection morphogenesis • neuron differentiation • neuron projection morphogenesis • cell differentiation • positive regulation of cell projection organization • positive regulation of developmental growth • regulation of cell projection organization • positive regulation of cell development • developmental growth involved in morphogenesis • generation of neurons • regulation of neuron projection development • positive regulation of cellular component organization • cellular developmental process • regulation of developmental process • plasma membrane bounded cell projection morphogenesis • cell development • cell growth • cell morphogenesis • regulation of axon extension • regulation of nervous system development • neurogenesis • regulation of axon extension involved in axon guidance • regulation of extent of cell growth • positive regulation of cell differentiation • regulation of axonogenesis • positive regulation of neurogenesis • axon extension involved in axon guidance • positive regulation of axon extension • positive regulation of axonogenesis • regulation of anatomical structure morphogenesis • regulation of cell size • neuron projection extension • regulation of multicellular organismal development • regulation of developmental growth • plasma membrane bounded cell projection organization • developmental cell growth • growth • axon guidance • positive regulation of cell growth • axon development • regulation of cell growth • cell morphogenesis involved in neuron differentiation • anatomical structure morphogenesis • positive regulation of growth • neuron projection guidance • neuron development • regulation of plasma membrane bounded cell projection organization • CXCL12-activated CXCR4 signaling pathway • C-X-C chemokine receptor CXCR4 signaling pathway • negative regulation of locomotion • regulation of leukocyte adhesion to vascular endothelial cell • leukocyte cell-cell adhesion • negative regulation of cell adhesion • leukocyte tethering or rolling • negative regulation of leukocyte tethering or rolling • cell-cell adhesion • negative regulation of cellular extravasation • cellular extravasation • regulation of cell-cell adhesion • negative regulation of cell migration • regulation of cell adhesion • negative regulation of leukocyte adhesion to vascular endothelial cell • regulation of leukocyte tethering or rolling • negative regulation of leukocyte migration • negative regulation of leukocyte cell-cell adhesion • negative regulation of immune system process • leukocyte adhesion to vascular endothelial cell • negative regulation of cell-cell adhesion • regulation of leukocyte cell-cell adhesion • negative regulation of cell motility • regulation of cellular extravasation • monoamine transport • regulation of catecholamine secretion • organic hydroxy compound transport • positive regulation of secretion by cell • dopamine transport • positive regulation of amine transport • catecholamine transport • positive regulation of secretion • positive regulation of catecholamine secretion • dopamine secretion • positive regulation of dopamine secretion • catecholamine secretion • amine transport • regulation of amine transport • regulation of dopamine secretion • vasculature development • regulation of vasculature development • circulatory system development • positive regulation of vasculature development • regulation of leukocyte apoptotic process • dendritic cell apoptotic process • negative regulation of dendritic cell apoptotic process • leukocyte apoptotic process • negative regulation of leukocyte apoptotic process • regulation of dendritic cell apoptotic process • positive regulation of cell adhesion • positive regulation of neuron differentiation • regulation of neuron differentiation • biological process involved in interspecies interaction between organisms • response to other organism • response to external biotic stimulus • response to virus • response to biotic stimulus • neuron migration • animal organ regeneration • regeneration • positive regulation of cell population proliferation • endothelial cell proliferation • positive regulation of epithelial cell proliferation • regulation of endothelial cell proliferation • regulation of cell population proliferation • positive regulation of endothelial cell proliferation • regulation of epithelial cell proliferation • epithelial cell proliferation • circulatory system process • blood circulation • cell surface • external side of plasma membrane • extracellular matrix • external encapsulating structure • molecular transducer activity • coreceptor activity • signaling receptor activity • cytoskeletal protein binding • myosin light chain binding • myosin binding • C-C chemokine binding • chemokine binding • cytokine binding • G protein-coupled chemoattractant receptor activity • C-X-C motif chemokine 12 receptor activity • C-X-C chemokine receptor activity • chemokine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • cytokine receptor activity • immune receptor activity • ubiquitin protein ligase binding • ubiquitin-like protein ligase binding • enzyme binding • virus receptor activity • exogenous protein binding • C-C chemokine receptor activity • ubiquitin binding • ubiquitin-like protein binding • actin binding • membrane organization • myelination • myelin maintenance • axon ensheathment • ensheathment of neurons • plasma membrane organization • endomembrane system organization • dendritic cell chemotaxis • dendritic cell migration • positive regulation of cytosolic calcium ion concentration • calcium-mediated signaling • intracellular signaling cassette • positive regulation of cell communication • positive regulation of signal transduction • positive regulation of macrophage migration inhibitory factor signaling pathway • positive regulation of response to cytokine stimulus • macrophage migration inhibitory factor signaling pathway • regulation of macrophage migration inhibitory factor signaling pathway • regulation of cytokine-mediated signaling pathway • regulation of response to cytokine stimulus • positive regulation of cytokine-mediated signaling pathway • positive regulation of signaling • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • inflammatory response • regulation of gliogenesis • positive regulation of gliogenesis • gliogenesis • positive regulation of oligodendrocyte differentiation • regulation of glial cell differentiation • positive regulation of glial cell differentiation • oligodendrocyte differentiation • glial cell differentiation • regulation of oligodendrocyte differentiation • cell leading edge • anchoring junction • cytoplasmic vesicle • intracellular vesicle • early endosome • endosome • late endosome
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • Interleukin 8-like chemokines • G protein-coupled receptor-like
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • Interleukin 8-like chemokines • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	CXCL12
UniProt	P48061
Sequence	>8K3Z_nogp_Chain_L K P V S L S Y R C P C R F F E S H V A R A N V K H L K I L N T P N C A L Q I V A R L K N N N R Q V C I D P K L K W I Q E Y L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P61073
Sequence	>8K3Z_nogp_Chain_R K E P C F R E E N A N F N K I F L P T I Y S I I F L T G I V G N G L V I L V M G Y Q K K L R S M T D K Y R L H L S V A D L L F V I T L P F W A V D A V A N W Y F G N F L C K A V H V I Y T V N L Y S S V L I L A F I S L D R Y L A I V H A T N S Q R P R K L L A E K V V Y V G V W I P A L L L T I P D F I F A N V S E A D D R Y I C D R F Y P N D L W V V V F Q F Q H I M V G L I L P G I V I L S C Y C I I I S K L S H S K G H Q K R K A L K T T V I L I L A F F A C W L P Y Y I G I S I D S F I L L E I I K Q G C E F E N T V H K W I S I T E A L A F F H C C L N P I L Y A F L G A K F K T S A Q H A L T S V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	3ODU	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	2.5	2010-10-27	doi.org/10.1126/science.1194396
	3OE0	A	Protein	Chemokine	CXCR4	Homo sapiens	CVX15	-	-	2.9	2010-10-27	doi.org/10.1126/science.1194396
	3OE6	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.2	2010-10-27	doi.org/10.1126/science.1194396
	3OE8	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.1	2010-10-27	doi.org/10.1126/science.1194396
	3OE9	A	Protein	Chemokine	CXCR4	Homo sapiens	IT1t	-	-	3.1	2010-10-27	doi.org/10.1126/science.1194396
	4RWS	A	Protein	Chemokine	CXCR4	Homo sapiens	vMIP-II	-	-	3.1	2015-02-11	doi.org/10.1126/science.1261064
	8K3Z	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	Gi1/β1/γ1	2.81	2024-07-17	doi.org/10.1016/j.celrep.2024.114578
	8K3Z (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-		2.81	2024-07-17	doi.org/10.1016/j.celrep.2024.114578
	8ZPL	A	Protein	Chemokine	CXCR4	Homo sapiens	HF51116	-	-	3.01	2025-02-26	doi.org/10.1073/pnas.2425795122
	8ZPM	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD070	-	-	3.2	2025-02-26	doi.org/10.1073/pnas.2425795122
	8ZPN	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-	-	3.31	2025-02-26	doi.org/10.1073/pnas.2425795122
	8YU7	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	-	3.01	2025-03-05	doi.org/10.1016/j.celrep.2025.115255
	9MDU	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	-	2.9	2025-09-10	To be published
	9ME1	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	-	3.37	2025-09-10	To be published
	9MEJ	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120	-	-	3.99	2025-09-10	To be published
	9MEN	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120 (V3 loop)	-	-	3.57	2025-09-10	To be published
	9MET	A	Protein	Chemokine	CXCR4	Homo sapiens	Gp120; CD4	-	-	5.65	2025-09-10	To be published
	9MEU	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	-	3.46	2025-09-10	To be published
	8U4N	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-	Gi1/β1/γ2	2.72	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4N (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	-		2.72	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4O	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-	Gi1/β1/γ2	3.29	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4O (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	-		3.29	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4P	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-	Gi1/β1/γ2	3.15	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4P (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	-		3.15	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4Q	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	Gi1/β1/γ2	3.36	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4Q (No Gprot)	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-		3.36	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4R	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.1	2024-03-13	doi.org/10.1101/2024.02.09.579708
	8U4S	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.35	2024-03-13	doi.org/10.1038/s41594-024-01397-1
	8U4T	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	-	-	3.38	2024-03-13	doi.org/10.1038/s41594-024-01397-1

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8K3Z_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.